Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" ACKR1 "CCBP1, CD234, DARC, Dfy, FY, GPD" ENSG00000213088 "Atypical chemokine receptor 1 (Duffy blood group)" Q16570 1 159203307-159206500 "Blood group antigen proteins, CD markers, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood group antigen, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 310.2" "Group enriched" "Detected in many" 10 "Adipocytes: 571.8;Endothelial cells: 840.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 5.8;Brain cancer: 1.7;Leukemia: 1.5;Neuroblastoma: 2.2;skin cancer: 2.2" "Breast - Endothelial cells, Colon - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016421, HPA017672" Enhanced NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA016421: AB_1849219, HPA017672: AB_1849221" "unprognostic (8.74e-3)" "prognostic favorable (2.52e-5)" "unprognostic (9.73e-2)" "unprognostic (1.91e-1)" "unprognostic (2.34e-3)" "unprognostic (3.84e-3)" "prognostic favorable (1.48e-4)" "unprognostic (7.80e-2)" "unprognostic (2.22e-1)" "unprognostic (3.46e-2)" "unprognostic (1.65e-3)" "unprognostic (1.81e-1)" "unprognostic (3.82e-3)" "unprognostic (5.17e-3)" "unprognostic (2.40e-1)" "prognostic unfavorable (9.76e-4)" "unprognostic (2.30e-2)" ACKR2 "CCBP2, CCR10, CCR9, CMKBR9, D6" ENSG00000144648 "Atypical chemokine receptor 2" O00590 3 42804752-42887974 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 9.1;placenta: 15.4" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 33.3;Extravillous trophoblasts: 117.3;Lymphatic endothelial cells: 37.3;Syncytiotrophoblasts: 78.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.8;NK-cell: 1.0" "Group enriched" "Detected in many" 7 "granulocytes: 3.8;NK-cells: 1.0" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 5 "amygdala: 2.2;basal ganglia: 7.9;cerebral cortex: 4.9;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "HPA013819, HPA073493" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Liver - Plasma proteins" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Extravillous trophoblasts - Unknown function" 7 "Vesicles, Cytosol" Nucleoplasm "HPA013819: AB_1846126, HPA073493: AB_2686610" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (1.90e-2)" "unprognostic (8.15e-2)" "unprognostic (7.51e-2)" "unprognostic (1.54e-2)" "unprognostic (1.21e-3)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "unprognostic (6.20e-2)" "unprognostic (8.47e-2)" "unprognostic (8.45e-2)" "unprognostic (1.13e-4)" "unprognostic (5.13e-3)" "unprognostic (3.22e-1)" "unprognostic (5.58e-3)" "unprognostic (6.09e-2)" ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 167.3;Lymphatic endothelial cells: 152.7;monocytes: 47.5;Smooth muscle cells: 61.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cancer enhanced" "Detected in many" "Kidney cancer: 106.8" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 7: Adipose tissue - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 53: Fibroblasts - ECM organization" 3 "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" ACKR4 "CCBP2, CCR11, CCRL1, CCX-CKR, PPR1, VSHK1" ENSG00000129048 "Atypical chemokine receptor 4" Q9NPB9 3 132597270-132618967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 15.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 17.0;Ciliated cells: 12.9;Exocrine glandular cells: 9.5;Fibroblasts: 17.8;Gastric mucus-secreting cells: 8.3;Proximal enterocytes: 20.0" "Cancer enhanced" "Detected in many" "stomach cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lymphoma: 4.4" "Thyroid - Fibroblasts" "Group enriched" "Detected in some" 7 "cerebellum: 4.7;pons and medulla: 1.5" "Low region specificity" "Detected in all" HPA054926 Approved Vesicles,Mitochondria NA NA "Cluster 45: Intestine - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Vesicles, Mitochondria" "HPA054926: " "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (2.62e-2)" "unprognostic (8.27e-2)" "unprognostic (5.17e-2)" "unprognostic (4.55e-3)" "unprognostic (8.93e-2)" "unprognostic (2.26e-1)" "unprognostic (4.85e-2)" "unprognostic (4.20e-3)" "unprognostic (1.03e-3)" "unprognostic (2.69e-3)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.18e-1)" "unprognostic (1.22e-1)" ADCYAP1R1 "PAC1, PAC1R, PACAPR" ENSG00000078549 "ADCYAP receptor type I" P41586 7 31052308-31111474 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 79.0;fallopian tube: 29.2" "Group enriched" "Detected in some" 4 "Astrocytes: 54.2;Inhibitory neurons: 43.7" "Cancer enriched" "Detected in some" 11 "glioma: 45.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Neuroblastoma: 36.1" "Pancreas - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030739, HPA049877" Enhanced Enhanced Vesicles NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 8: Neurons - Neuronal signaling" Vesicles "HPA030739: AB_2732461, HPA049877: AB_2680928" "unprognostic (5.43e-2)" "unprognostic (1.16e-1)" "unprognostic (2.16e-2)" "prognostic favorable (5.78e-4)" "unprognostic (2.17e-1)" "unprognostic (8.36e-2)" "unprognostic (4.93e-2)" "unprognostic (5.75e-2)" "unprognostic (3.50e-2)" "unprognostic (3.88e-1)" "unprognostic (1.58e-1)" "unprognostic (6.67e-3)" "unprognostic (6.43e-4)" "unprognostic (1.09e-3)" "unprognostic (9.55e-2)" "unprognostic (3.85e-2)" "unprognostic (2.75e-4)" ADGRA1 "GPR123, KIAA1828" ENSG00000197177 "Adhesion G protein-coupled receptor A1" Q86SQ6 10 133087924-133131675 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 26.9" "Group enriched" "Detected in some" 8 "Excitatory neurons: 24.4;Horizontal cells: 23.9;Inhibitory neurons: 23.6;Oligodendrocyte precursor cells: 27.4" "Cancer enriched" "Detected in single" 13 "glioma: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 6.5" "Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042773 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "HPA042773: AB_10794764" "unprognostic (8.31e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (1.54e-1)" "unprognostic (1.09e-2)" "unprognostic (7.51e-3)" "unprognostic (2.48e-2)" "unprognostic (3.33e-1)" "unprognostic (1.66e-1)" ADGRA2 "DKFZp434C211, DKFZp434J0911, FLJ14390, GPR124, KIAA1531, TEM5" ENSG00000020181 "Adhesion G protein-coupled receptor A2" Q96PE1 8 37784191-37844896 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 29.4;Endometrial stromal cells: 45.0;Fibroblasts: 39.6;Leydig cells: 52.3;Lymphatic endothelial cells: 58.2;Muller glia cells: 26.3;Peritubular cells: 40.6;Smooth muscle cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 29.9" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblast_1, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008984, HPA012393" Uncertain Supported "Vesicles,Plasma membrane" NA NA 270000 "Cluster 62: Connective tissue - ECM organization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "Plasma membrane" Vesicles "HPA008984: , HPA012393: AB_1849256" "unprognostic (1.63e-1)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (6.34e-2)" "unprognostic (1.38e-1)" "unprognostic (3.75e-2)" "unprognostic (1.15e-2)" "unprognostic (1.20e-2)" "unprognostic (3.55e-2)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.18e-7)" "unprognostic (2.65e-2)" "unprognostic (4.90e-2)" "unprognostic (6.12e-2)" "unprognostic (4.60e-3)" ADGRA3 "FLJ38547, GPR125, PGR21" ENSG00000152990 "Adhesion G protein-coupled receptor A3" Q8IWK6 4 22345071-22516066 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.5" "Cell type enhanced" "Detected in many" "Astrocytes: 210.2;Hepatocytes: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008904 Uncertain "Intracellular and membrane" Receptor NA NA 280000 "Cluster 69: Liver - Oxidoreductase activity" "Cluster 39: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 47: Astrocytes - Unknown function" "HPA008904: AB_1849258" "unprognostic (3.70e-1)" "unprognostic (9.01e-2)" "unprognostic (5.32e-3)" "unprognostic (8.27e-3)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (8.15e-2)" "unprognostic (1.81e-2)" "unprognostic (1.02e-1)" "unprognostic (3.91e-2)" "unprognostic (8.77e-2)" "unprognostic (1.88e-1)" "unprognostic (1.78e-3)" "unprognostic (1.76e-1)" "unprognostic (1.13e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-3)" ADGRB1 BAI1 ENSG00000181790 "Adhesion G protein-coupled receptor B1" O14514 8 142449430-142545009 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity, Myogenesis, Neurogenesis, Phagocytosis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 46.9" "Cell type enhanced" "Detected in some" "Astrocytes: 55.7;Bipolar cells: 24.0;Excitatory neurons: 45.9;Horizontal cells: 46.6;Inhibitory neurons: 36.4;Oligodendrocyte precursor cells: 66.5" "Cancer enriched" "Detected in many" 5 "glioma: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Secreted in brain" Receptor NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 70: DU4475 - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 2 "unprognostic (9.57e-4)" "unprognostic (1.28e-1)" "unprognostic (3.87e-3)" "unprognostic (8.50e-3)" "unprognostic (9.98e-2)" "unprognostic (5.87e-2)" "unprognostic (3.39e-1)" "unprognostic (2.14e-2)" "unprognostic (2.76e-1)" "unprognostic (2.55e-1)" "unprognostic (6.48e-2)" "unprognostic (3.43e-1)" "unprognostic (7.30e-11)" "unprognostic (6.27e-2)" "unprognostic (7.42e-2)" "unprognostic (4.52e-3)" "unprognostic (3.29e-2)" ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 77.5" "Cell type enhanced" "Detected in many" "Astrocytes: 19.8;Bipolar cells: 12.8;Excitatory neurons: 53.9;Horizontal cells: 27.7;Inhibitory neurons: 13.2;Oligodendrocyte precursor cells: 19.3" "Cancer enriched" "Detected in many" 4 "glioma: 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069175 Supported "Plasma membrane" NA NA 32000 "Cluster 61: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA069175: " "prognostic favorable (6.46e-4)" "unprognostic (1.74e-1)" "unprognostic (7.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (8.17e-4)" "prognostic unfavorable (4.02e-5)" "unprognostic (2.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-3)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (1.75e-3)" "unprognostic (7.98e-2)" ADGRB3 "BAI3, KIAA0550" ENSG00000135298 "Adhesion G protein-coupled receptor B3" O60242 6 68635282-69390571 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 29.2;pituitary gland: 23.1" "Group enriched" "Detected in many" 10 "Astrocytes: 1702.7;Excitatory neurons: 3716.2;Inhibitory neurons: 2624.2;Oligodendrocyte precursor cells: 1910.7;Oligodendrocytes: 1127.0" "Cancer enriched" "Detected in single" 10 "glioma: 3.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 12.1" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Lung - Fibroblast_1, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 8600 "Cluster 22: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 34: Neurons - Neuronal signaling" 3 "unprognostic (1.71e-1)" "unprognostic (9.01e-2)" "unprognostic (2.69e-1)" "unprognostic (3.72e-3)" "unprognostic (3.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (5.08e-5)" "unprognostic (4.93e-2)" "unprognostic (1.32e-1)" "unprognostic (1.55e-3)" "unprognostic (2.43e-1)" "unprognostic (1.01e-1)" "unprognostic (8.16e-3)" ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 60.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 28.1;Cardiomyocytes: 34.0;Endometrial stromal cells: 45.9;Fibroblasts: 31.6;Mesothelial cells: 75.6;Microglial cells: 24.2;Sertoli cells: 32.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.9" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Nuclear speckles,Plasma membrane" NA NA 1400000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 1 "Plasma membrane" "Nucleoplasm, Nuclear speckles" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" ADGRE1 "EMR1, TM7LN3" ENSG00000174837 "Adhesion G protein-coupled receptor E1" Q14246 19 6887566-6940459 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.7;lymphoid tissue: 14.4" "Group enriched" "Detected in some" 5 "Kupffer cells: 32.4;monocytes: 87.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 166.6;eosinophil: 325.5" "Group enriched" "Detected in many" 18 "granulocytes: 325.5;monocytes: 105.3" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 13.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA052809 Uncertain NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 29: Monocytes - Innate immune response" "HPA052809: AB_2681959" "unprognostic (2.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.32e-1)" "unprognostic (7.88e-2)" "unprognostic (1.02e-1)" "unprognostic (6.93e-5)" "unprognostic (6.77e-2)" "unprognostic (1.18e-1)" "unprognostic (5.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.37e-7)" "unprognostic (6.69e-2)" "unprognostic (3.33e-4)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" ADGRE2 "CD312, EMR2" ENSG00000127507 "Adhesion G protein-coupled receptor E2" Q9UHX3 19 14732392-14778560 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Cell adhesion, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.8" "Cell type enhanced" "Detected in many" "granulocytes: 72.9;Kupffer cells: 72.1;Macrophages: 72.3;monocytes: 238.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 70.2;eosinophil: 74.8;intermediate monocyte: 46.9;neutrophil: 55.8;non-classical monocyte: 90.2" "Group enriched" "Detected in many" 9 "granulocytes: 74.8;monocytes: 90.2" "Cancer enhanced" "Detected in many" "Leukemia: 7.7" "Lung - Neutrophil_2" "Low region specificity" "Detected in many" HPA055200 Uncertain Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" 18 Vesicles Cytosol "HPA055200: " "unprognostic (2.46e-2)" "unprognostic (3.58e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (9.10e-2)" "unprognostic (3.58e-2)" "unprognostic (2.77e-2)" "unprognostic (3.88e-2)" "unprognostic (4.28e-1)" "unprognostic (1.22e-1)" "unprognostic (2.32e-1)" "unprognostic (2.70e-2)" "prognostic unfavorable (4.35e-6)" "unprognostic (1.46e-1)" "unprognostic (2.45e-3)" "unprognostic (2.50e-1)" "unprognostic (1.01e-1)" ADGRE3 EMR3 ENSG00000131355 "Adhesion G protein-coupled receptor E3" Q9BY15 19 14619117-14690027 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.1;lymphoid tissue: 5.9" "Cell type enhanced" "Detected in some" "Macrophages: 7.7;Microglial cells: 3.6;monocytes: 21.0;Mucus glandular cells: 3.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.1" "Group enriched" "Detected in many" 7 "basophil: 282.8;eosinophil: 510.3;neutrophil: 491.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 510.3" "Cancer enriched" "Detected in single" 7 "Leukemia: 1.0" "Adipose visceral - Neutrophils, Stomach - Neutrophils" "Not detected" "Not detected" HPA015638 Uncertain "Secreted to blood" Receptor NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "HPA015638: AB_1848039" "unprognostic (2.11e-4)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (5.63e-2)" "unprognostic (4.53e-2)" "unprognostic (1.14e-1)" "unprognostic (8.07e-2)" "unprognostic (9.61e-2)" "unprognostic (9.11e-4)" "unprognostic (4.68e-2)" "unprognostic (2.41e-1)" "unprognostic (1.13e-1)" "unprognostic (7.06e-3)" "unprognostic (1.51e-1)" "unprognostic (1.20e-1)" "unprognostic (6.67e-2)" ADGRE5 "CD97, TM7LN1" ENSG00000123146 "Adhesion G protein-coupled receptor E5" P48960 19 14380501-14408725 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 209.5" "Cell type enhanced" "Detected in many" "dendritic cells: 152.0;monocytes: 445.8;NK-cells: 300.7;T-cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013707 Enhanced Approved Cytosol "Secreted to blood" Receptor NA Yes 10000000 2400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" Cytosol "HPA013707: AB_1846345" "unprognostic (3.16e-1)" "unprognostic (1.80e-1)" "unprognostic (5.10e-2)" "unprognostic (2.30e-1)" "unprognostic (2.85e-2)" "unprognostic (7.24e-2)" "prognostic unfavorable (3.73e-5)" "unprognostic (7.51e-2)" "unprognostic (6.06e-3)" "unprognostic (3.14e-2)" "unprognostic (1.08e-3)" "unprognostic (2.37e-1)" "prognostic unfavorable (1.87e-6)" "unprognostic (2.08e-2)" "unprognostic (4.14e-2)" "unprognostic (2.44e-2)" "unprognostic (6.41e-2)" ADGRF1 "GPR110, hGPCR36, PGR19" ENSG00000153292 "Adhesion G protein-coupled receptor F1" Q5T601 6 46997708-47042350 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 17.0;kidney: 19.7;urinary bladder: 41.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 62.2;Ciliated cells: 66.8;Club cells: 124.5;Collecting duct cells: 101.1;Glandular and luminal cells: 55.9;Ionocytes: 157.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 62.2" "Lung - Alveolar cells type 2, Pancreas - Ductal cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA038438 Approved "Secreted - unknown location" Receptor NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "HPA038438: AB_10672645" "unprognostic (4.83e-4)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (6.71e-3)" "unprognostic (1.95e-3)" "unprognostic (3.02e-3)" "unprognostic (7.76e-2)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (4.20e-2)" "unprognostic (3.64e-3)" "unprognostic (1.99e-1)" "prognostic favorable (1.35e-5)" "unprognostic (7.41e-2)" "unprognostic (8.39e-2)" "unprognostic (1.76e-1)" "unprognostic (1.08e-2)" ADGRF3 "GPR113, hGPCR37, PGR23" ENSG00000173567 "Adhesion G protein-coupled receptor F3" Q8IZF5 2 26308173-26346817 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "pancreas: 1.0" "Cell type enhanced" "Detected in some" "Astrocytes: 10.8;Early spermatids: 6.1;Late spermatids: 29.8;Microglial cells: 5.4;Oligodendrocytes: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Ascending Loop of Henle cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA044500 Uncertain Approved "Golgi apparatus,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 11: Late spermatids - Unknown function" "Golgi apparatus" Cytosol "HPA044500: AB_10794290" "unprognostic (9.58e-3)" "unprognostic (2.13e-2)" "unprognostic (4.07e-1)" "unprognostic (1.36e-1)" "unprognostic (6.39e-2)" "unprognostic (6.68e-4)" "unprognostic (8.98e-3)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.59e-1)" "unprognostic (9.66e-4)" "unprognostic (2.29e-1)" "unprognostic (8.09e-2)" "unprognostic (3.53e-2)" "unprognostic (2.58e-1)" "unprognostic (4.08e-2)" "unprognostic (8.70e-5)" ADGRF4 "FLJ38076, GPR115, PGR18" ENSG00000153294 "Adhesion G protein-coupled receptor F4" Q8IZF3 6 47685864-47722021 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 17.8;skin 1: 37.7" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.6;Distal enterocytes: 8.3;Extravillous trophoblasts: 17.3;Squamous epithelial cells: 16.5;Suprabasal keratinocytes: 32.1;Syncytiotrophoblasts: 9.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 8.2" "Region enriched" "Detected in single" 5 "hypothalamus: 4.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.7" "Prostate - Urothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "spinal cord: 2.0" "HPA007131, HPA007158" Enhanced Uncertain Mitochondria NA NA "Cluster 13: Skin - Cornification" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Non-specific - Mixed function" Mitochondria "HPA007131: AB_2667756, HPA007158: AB_1849254" "unprognostic (1.40e-2)" "unprognostic (7.06e-3)" "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (3.79e-2)" "unprognostic (3.77e-2)" "unprognostic (2.04e-3)" "unprognostic (2.64e-1)" "unprognostic (3.47e-1)" "prognostic unfavorable (5.52e-4)" "unprognostic (2.86e-1)" "unprognostic (1.66e-8)" "unprognostic (1.62e-3)" "unprognostic (2.01e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-1)" ADGRF5 "DKFZp564O1923, GPR116, KIAA0758" ENSG00000069122 "Adhesion G protein-coupled receptor F5" Q8IZF2 6 46852522-46954943 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 102.7" "Cell type enhanced" "Detected in many" "Adipocytes: 393.9;Alveolar cells type 1: 205.3;Alveolar cells type 2: 303.0;Endothelial cells: 214.3;Microglial cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 11.7;pancreatic cancer: 6.7;Sarcoma: 6.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA 55000000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "unprognostic (8.45e-2)" "unprognostic (3.00e-3)" "unprognostic (1.13e-1)" "unprognostic (3.26e-1)" "unprognostic (6.51e-2)" "unprognostic (1.89e-2)" "unprognostic (5.76e-2)" "unprognostic (9.00e-3)" "unprognostic (7.80e-2)" "unprognostic (3.32e-1)" "unprognostic (1.42e-1)" "unprognostic (4.56e-2)" "prognostic favorable (8.84e-5)" "unprognostic (1.43e-2)" "unprognostic (5.91e-2)" "unprognostic (2.82e-2)" "unprognostic (3.78e-2)" ADGRG1 "GPR56, TM7LN4, TM7XN1" ENSG00000205336 "Adhesion G protein-coupled receptor G1" Q9Y653 16 57610652-57665580 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, G-protein coupled receptor, Heparin-binding, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 209.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 220.3;Melanocytes: 140.9;NK-cells: 180.6;Syncytiotrophoblasts: 178.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 160.5" "Lineage enriched" "Detected in many" 5 "T-cells: 160.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046065 Uncertain "Secreted to blood" Receptor NA NA 32000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: NK-cells - Adaptive immune response" "HPA046065: AB_2679521" "unprognostic (4.91e-3)" "unprognostic (1.70e-1)" "unprognostic (2.69e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-3)" "prognostic unfavorable (2.53e-4)" "unprognostic (4.87e-2)" "unprognostic (8.35e-2)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (1.52e-1)" "unprognostic (1.36e-2)" "prognostic favorable (5.52e-7)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (3.33e-1)" "unprognostic (1.98e-1)" ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1198.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 10.6;Mucus glandular cells: 11.4;Oligodendrocyte precursor cells: 9.4;Prostatic glandular cells: 14.5;Secretory cells: 21.7;Serous glandular cells: 29.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 16.6" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 75: Serous glandular cells - Salivary secretion" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" ADGRG3 "GPR97, Pb99, PGR26" ENSG00000182885 "Adhesion G protein-coupled receptor G3" Q86Y34 16 57668277-57689378 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 145.6" "Cell type enriched" "Detected in some" 5 "Lymphatic endothelial cells: 41.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 5 "cerebral cortex: 22.7" "Immune cell enhanced" "Detected in some" "eosinophil: 142.5;neutrophil: 170.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 170.3" "Group enriched" "Detected in some" 9 "Leukemia: 2.4;lymphoma: 3.1" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" HPA040469 Uncertain NA NA 1200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 6: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 74: Neutrophils - Degranulation" 9 "HPA040469: AB_10794032" "unprognostic (4.41e-3)" "unprognostic (3.49e-2)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" "unprognostic (8.84e-2)" "unprognostic (1.64e-2)" "unprognostic (1.50e-4)" "unprognostic (5.25e-3)" "unprognostic (1.22e-2)" "unprognostic (2.22e-1)" "unprognostic (1.93e-1)" "unprognostic (1.53e-1)" "unprognostic (2.67e-3)" "unprognostic (4.75e-2)" "unprognostic (3.77e-1)" "unprognostic (1.00e-1)" "unprognostic (2.90e-1)" ADGRG4 "GPR112, PGR17, RP1-299I16" ENSG00000156920 "Adhesion G protein-coupled receptor G4" Q8IZF6 X 136300963-136416890 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 1.0;intestine: 2.4;retina: 1.1" "Group enriched" "Detected in some" 5 "Enteroendocrine cells: 61.8;Paneth cells: 44.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035324 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA035324: AB_10671512" "unprognostic (3.40e-3)" "unprognostic (7.68e-5)" "unprognostic (7.61e-2)" ADGRG5 "GPR114, PGR27" ENSG00000159618 "Adhesion G protein-coupled receptor G5" Q8IZF4 16 57542643-57591681 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 3.8;lymphoid tissue: 10.2" "Cell type enhanced" "Detected in some" "B-cells: 6.2;dendritic cells: 30.0;Microglial cells: 10.7;NK-cells: 27.1;Plasma cells: 16.9;T-cells: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 126.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 11.0;lymphoma: 6.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Heart muscle - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA007133 Enhanced Approved "Nucleoplasm,Nuclear membrane,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "Nuclear membrane, Vesicles" Nucleoplasm "HPA007133: AB_1849253" "unprognostic (6.11e-3)" "prognostic favorable (4.25e-4)" "unprognostic (2.70e-1)" "unprognostic (2.27e-2)" "unprognostic (6.14e-2)" "unprognostic (1.14e-2)" "unprognostic (6.43e-2)" "unprognostic (1.42e-2)" "unprognostic (8.09e-4)" "unprognostic (3.80e-3)" "unprognostic (3.02e-3)" "unprognostic (1.91e-1)" "unprognostic (4.37e-3)" "unprognostic (7.69e-3)" "unprognostic (4.52e-1)" "unprognostic (1.62e-3)" "unprognostic (6.32e-3)" ADGRG6 "FLJ14937, GPR126" ENSG00000112414 "Adhesion G protein-coupled receptor G6" Q86SQ4 6 142301854-142446266 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 69.7;placenta: 45.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 110.5;Suprabasal keratinocytes: 40.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA017346 Approved NA NA 110000000 "Cluster 11: Liver - Plasma proteins" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Hepatocytes - Metabolism" "HPA017346: AB_1849260" "unprognostic (1.04e-2)" "unprognostic (2.72e-2)" "unprognostic (7.37e-2)" "unprognostic (3.00e-2)" "unprognostic (8.64e-4)" "unprognostic (1.67e-1)" "unprognostic (2.98e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.78e-5)" "unprognostic (4.46e-1)" "unprognostic (6.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.97e-2)" "unprognostic (4.59e-2)" ADGRG7 "FLJ14454, GPR128" ENSG00000144820 "Adhesion G protein-coupled receptor G7" Q96K78 3 100609601-100695479 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "intestine: 41.7;liver: 24.0" "Cell type enhanced" "Detected in some" "Hepatocytes: 22.4;Intestinal goblet cells: 9.5;Paneth cells: 20.1;Proximal enterocytes: 34.0" "Cancer enhanced" "Detected in some" "stomach cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.8;Brain cancer: 1.3" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA056451 Approved "Plasma membrane" NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 3 "Plasma membrane" "HPA056451: " "unprognostic (1.65e-1)" "unprognostic (1.10e-1)" "unprognostic (2.79e-1)" "unprognostic (8.46e-3)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (9.37e-3)" "unprognostic (2.84e-5)" "unprognostic (1.17e-1)" "unprognostic (2.16e-1)" "unprognostic (6.77e-2)" ADGRL1 "CIRL1, KIAA0821, LEC2, LPHN1" ENSG00000072071 "Adhesion G protein-coupled receptor L1" O94910 19 14147743-14206187 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.2;Excitatory neurons: 51.0;Horizontal cells: 54.1;Inhibitory neurons: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037974 Uncertain NA NA 180000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 65: Cerebellum - Nervous system development" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 1 "HPA037974: AB_10675623" "unprognostic (5.52e-2)" "unprognostic (3.89e-1)" "unprognostic (1.04e-1)" "unprognostic (5.52e-3)" "unprognostic (6.29e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" "unprognostic (5.39e-2)" "unprognostic (2.73e-1)" "unprognostic (5.68e-2)" "prognostic favorable (1.14e-4)" "unprognostic (2.09e-1)" "prognostic favorable (4.45e-4)" "unprognostic (7.65e-3)" "unprognostic (1.32e-1)" "unprognostic (3.06e-2)" "unprognostic (2.18e-1)" ADGRL2 "CIRL2, KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81993932 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 9 "Excitatory neurons: 873.5;Inhibitory neurons: 619.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Endothelial cells, Prostate - Fibroblasts, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" ADGRL3 "KIAA0768, LEC3, LPHN3" ENSG00000150471 "Adhesion G protein-coupled receptor L3" Q9HAR2 4 61200326-62078335 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.1" "Group enriched" "Detected in many" 11 "Astrocytes: 553.9;Excitatory neurons: 672.7;Inhibitory neurons: 706.4;Oligodendrocyte precursor cells: 1220.7;Oligodendrocytes: 551.2" "Cancer enriched" "Detected in some" 9 "glioma: 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 8.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Breast - Smooth muscle cells, Colon - Enteric glia cells, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skin - Outer root sheath cells, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015027, HPA015762, CAB022698" Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 1 "CAB022698: , HPA015027: AB_1853243, HPA015762: AB_1853245" "unprognostic (2.88e-2)" "unprognostic (1.12e-1)" "unprognostic (6.43e-4)" "unprognostic (1.79e-2)" "unprognostic (1.88e-1)" "unprognostic (7.56e-2)" "unprognostic (8.70e-2)" "unprognostic (5.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.28e-1)" "unprognostic (6.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.62e-5)" "unprognostic (1.03e-2)" "unprognostic (1.44e-1)" "unprognostic (9.85e-3)" "unprognostic (4.23e-3)" ADGRL4 "ELTD1, ETL" ENSG00000162618 "Adhesion G protein-coupled receptor L4" Q9HBW9 1 78889764-79282124 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.8" "Group enriched" "Detected in many" 6 "Adipocytes: 559.4;Endothelial cells: 298.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 12.2;thyroid cancer: 15.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA025229 Supported NA NA 3800000 "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA025229: AB_10602493" "unprognostic (2.67e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.32e-2)" "unprognostic (8.11e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "unprognostic (2.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.52e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (5.32e-3)" "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (3.85e-3)" ADGRV1 "DKFZp761P0710, FEB4, GPR98, KIAA0686, MASS1, USH2C, VLGR1" ENSG00000164199 "Adhesion G protein-coupled receptor V1" Q8WXG9 5 90529344-91164437 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Hydrolase, Receptor, Transducer" "Deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "adrenal gland: 516.2" "Cell type enriched" "Detected in many" 11 "Astrocytes: 2093.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 26.4" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067503 Approved Approved "Lipid droplets" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 47: Astrocytes - Unknown function" 1 "Lipid droplets" "HPA067503: AB_2685856" "unprognostic (1.29e-1)" "unprognostic (3.02e-1)" "unprognostic (3.69e-2)" "unprognostic (1.38e-1)" "unprognostic (4.01e-2)" "unprognostic (2.61e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-3)" "unprognostic (1.48e-2)" "unprognostic (1.87e-1)" "unprognostic (3.95e-3)" "unprognostic (7.50e-3)" "unprognostic (9.73e-7)" "unprognostic (1.87e-2)" "unprognostic (5.24e-2)" "unprognostic (3.48e-2)" "unprognostic (7.14e-2)" ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.2;testis: 20.9" "Cell type enhanced" "Detected in some" "Ductal cells: 12.9;Excitatory neurons: 17.5;Muller glia cells: 40.9;Oligodendrocyte precursor cells: 33.0;Oligodendrocytes: 29.3" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 51.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Podocytes, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 10: Muller glia cells - Visual perception" 5 "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" ADORA2A "ADORA2, RDC8" ENSG00000128271 "Adenosine A2a receptor" P29274 22 24417879-24442357 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 40.1;brain: 111.0;lymphoid tissue: 52.7" "Cell type enhanced" "Detected in some" "B-cells: 6.1;Gastric mucus-secreting cells: 1.8;Plasma cells: 9.1;T-cells: 3.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "basal ganglia: 200.5" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 45.6;Myeloma: 39.1" "Kidney - Endothelial cells" "Region enriched" "Detected in many" 9 "basal ganglia: 399.9" "Region enriched" "Detected in many" 50 "basal ganglia: 187.1" "CAB001943, HPA065566, HPA075997" Enhanced Supported NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 7: T-cells - T-cell receptor" 8 "CAB001943: , HPA065566: , HPA075997: AB_2732298" "unprognostic (7.30e-2)" "unprognostic (2.42e-2)" "unprognostic (3.30e-2)" "unprognostic (2.04e-1)" "unprognostic (7.44e-2)" "unprognostic (1.88e-3)" "unprognostic (9.85e-2)" "unprognostic (3.63e-1)" "unprognostic (2.88e-2)" "unprognostic (4.57e-3)" "unprognostic (2.15e-3)" "unprognostic (1.87e-3)" "unprognostic (6.81e-4)" "unprognostic (1.50e-1)" "unprognostic (9.78e-3)" "unprognostic (1.30e-1)" "unprognostic (7.10e-3)" ADORA2B ENSG00000170425 "Adenosine A2b receptor" P29275 17 15945130-15975746 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 16.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.2;Basal respiratory cells: 69.1;Basal squamous epithelial cells: 31.2;Langerhans cells: 31.5;Suprabasal keratinocytes: 36.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 17.3;myeloid DC: 10.5" "Group enriched" "Detected in many" 113 "dendritic cells: 10.5;granulocytes: 17.3;monocytes: 5.9" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA073747 Uncertain Cytosol NA Yes "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Squamous epithelial cells - Keratinization" 1 Cytosol "HPA073747: " "unprognostic (6.04e-3)" "unprognostic (1.22e-1)" "unprognostic (8.14e-2)" "unprognostic (1.32e-2)" "unprognostic (4.68e-1)" "unprognostic (7.88e-3)" "unprognostic (2.64e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "unprognostic (1.38e-1)" "unprognostic (1.66e-9)" "unprognostic (2.07e-1)" "unprognostic (3.49e-1)" "unprognostic (1.50e-2)" "unprognostic (2.84e-1)" ADORA3 "A3AR, AD026" ENSG00000282608 "Adenosine A3 receptor" P0DMS8 1 111499429-111503633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7" "Cell type enhanced" "Detected in some" "granulocytes: 13.8;Hofbauer cells: 16.7;Kupffer cells: 62.2;Late spermatids: 17.7;Macrophages: 31.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 40 "eosinophil: 602.8" "Lineage enriched" "Detected in many" 40 "granulocytes: 602.8" "Cancer enriched" "Detected in single" 6 "Leukemia: 1.9" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" ADRA1A "ADRA1C, ADRA1L1" ENSG00000120907 "Adrenoceptor alpha 1A" P35348 8 26748150-26867278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 21.0;liver: 58.3" "Cell type enhanced" "Detected in some" "Astrocytes: 100.0;Early spermatids: 34.5;Inhibitory neurons: 117.6;Late spermatids: 38.2;Oligodendrocyte precursor cells: 107.1" "Cancer enhanced" "Detected in some" "liver cancer: 0.9;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Bone cancer: 4.1" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029678, HPA029679, HPA076693" Approved Supported Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 83: Liver - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 3 Cytosol "Nucleoplasm, Vesicles" "HPA029678: AB_10602108, HPA029679: AB_2673143, HPA076693: " "unprognostic (1.27e-1)" "unprognostic (1.68e-2)" "unprognostic (1.99e-1)" "unprognostic (3.57e-1)" "unprognostic (5.04e-4)" "unprognostic (1.97e-1)" "unprognostic (9.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.58e-2)" "unprognostic (7.47e-2)" "unprognostic (1.71e-2)" "unprognostic (6.06e-3)" "unprognostic (7.41e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159973012 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 8.9;liver: 11.2;lymphoid tissue: 11.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 40.1;Hepatocytes: 13.5;Horizontal cells: 8.2;Inhibitory neurons: 31.2;Mesothelial cells: 12.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" NA NA "Cluster 69: Liver - Oxidoreductase activity" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane" "HPA074416: AB_2686688" "unprognostic (4.93e-3)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.00e-5)" "prognostic unfavorable (6.98e-4)" "unprognostic (4.08e-3)" "unprognostic (1.67e-3)" "unprognostic (1.68e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.28e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.40e-6)" "unprognostic (5.24e-4)" "unprognostic (2.54e-1)" "prognostic favorable (3.19e-5)" "unprognostic (1.59e-2)" ADRA1D "ADRA1, ADRA1A, ADRA1R" ENSG00000171873 "Adrenoceptor alpha 1D" P25100 20 4220630-4249287 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.8;cervix: 7.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.0;Inhibitory neurons: 2.3;Sertoli cells: 8.2;Smooth muscle cells: 6.8" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 27.8" "Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA038789 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Smooth muscle cells - Signal transduction" 7 "HPA038789: AB_10673475" "unprognostic (5.37e-2)" "unprognostic (4.65e-1)" "unprognostic (8.73e-2)" "unprognostic (7.75e-11)" "unprognostic (7.83e-3)" "unprognostic (1.54e-2)" "unprognostic (7.62e-2)" "unprognostic (7.82e-4)" "unprognostic (4.41e-3)" "unprognostic (8.37e-2)" "unprognostic (6.09e-2)" "unprognostic (7.24e-3)" "unprognostic (7.71e-7)" "unprognostic (5.21e-3)" "unprognostic (2.76e-1)" "unprognostic (6.01e-3)" "unprognostic (3.32e-5)" ADRA2A "ADRA2, ADRA2R, ADRAR" ENSG00000150594 "Adrenoceptor alpha 2A" P08913 10 111077029-111080907 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 48.9;cervix: 45.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 66.8;Glandular and luminal cells: 31.5;Paneth cells: 128.1;Smooth muscle cells: 84.9" "Cancer enhanced" "Detected in all" "pancreatic cancer: 17.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 11.9" "Adipose visceral - Adipocytes (Visceral), Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "unprognostic (3.87e-2)" "unprognostic (1.63e-2)" "unprognostic (1.38e-1)" "prognostic favorable (8.06e-4)" "unprognostic (1.36e-2)" "unprognostic (1.04e-1)" "unprognostic (4.78e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-1)" "unprognostic (4.64e-3)" "unprognostic (5.86e-2)" "unprognostic (5.63e-2)" "unprognostic (3.08e-6)" "unprognostic (1.45e-1)" "unprognostic (3.70e-2)" "unprognostic (1.35e-2)" "unprognostic (1.89e-3)" ADRA2B "ADRA2L1, ADRA2RL1, ADRARL1" ENSG00000274286 "Adrenoceptor alpha 2B" P18089 2 96112876-96116571 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 6.7;Ionocytes: 12.9;Langerhans cells: 12.0;Sertoli cells: 8.2;Smooth muscle cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Endothelial cells" "Group enriched" "Detected in some" 6 "basal ganglia: 2.5;cerebellum: 1.0;thalamus: 3.2" "Low region specificity" "Detected in many" "HPA066029, HPA074948" Approved Supported Vesicles,Cytosol NA NA "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" 1 Vesicles Cytosol "HPA066029: AB_2685599, HPA074948: " "unprognostic (6.16e-2)" "unprognostic (1.31e-2)" "unprognostic (1.76e-2)" "unprognostic (4.93e-4)" "unprognostic (1.84e-2)" "unprognostic (5.24e-2)" "unprognostic (6.80e-5)" "unprognostic (4.85e-2)" "unprognostic (1.69e-1)" "unprognostic (3.16e-2)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (2.21e-1)" "unprognostic (4.43e-2)" "unprognostic (3.39e-1)" "unprognostic (1.36e-1)" "unprognostic (6.55e-2)" ADRA2C "ADRA2L2, ADRA2RL2, ADRARL2" ENSG00000184160 "Adrenoceptor alpha 2C" P18825 4 3766348-3768526 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 82.1;endometrium 1: 55.7" "Cell type enhanced" "Detected in many" "Adipocytes: 24.5;Endometrial stromal cells: 133.1;Fibroblasts: 15.7;Secretory cells: 33.6;Smooth muscle cells: 26.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 22.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 18.1" "Thyroid - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "basal ganglia: 45.2" HPA057688 Uncertain NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 33: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 9: Endometrial stromal cells - Transcription" 10 "HPA057688: AB_2683503" "unprognostic (1.44e-2)" "unprognostic (2.21e-3)" "unprognostic (1.23e-1)" "unprognostic (2.02e-2)" "unprognostic (4.70e-2)" "unprognostic (1.11e-1)" "unprognostic (7.12e-2)" "unprognostic (6.69e-2)" "unprognostic (1.88e-1)" "unprognostic (3.71e-1)" "unprognostic (3.24e-2)" "unprognostic (9.08e-3)" "unprognostic (1.01e-2)" "unprognostic (6.00e-2)" "unprognostic (2.63e-1)" "unprognostic (1.72e-1)" "unprognostic (6.48e-2)" ADRB1 ADRB1R ENSG00000043591 "Adrenoceptor beta 1" P08588 10 114043866-114046904 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 22.9;lung: 12.7;placenta: 28.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 24.6;Cardiomyocytes: 74.7;Cytotrophoblasts: 79.8;Sertoli cells: 24.5;Syncytiotrophoblasts: 34.7" "Cancer enriched" "Detected in many" 10 "prostate cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bone cancer: 7.9" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067972 Enhanced NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 24: Cytotrophoblasts - Mitochondria" 4 "HPA067972: AB_2685936" "unprognostic (1.45e-3)" "unprognostic (1.18e-3)" "unprognostic (1.44e-1)" "unprognostic (4.92e-2)" "unprognostic (3.22e-1)" "unprognostic (8.88e-2)" "unprognostic (9.28e-2)" "unprognostic (3.52e-2)" "unprognostic (1.51e-1)" "unprognostic (1.96e-2)" "unprognostic (2.77e-4)" "unprognostic (1.33e-1)" "unprognostic (7.80e-3)" "unprognostic (1.53e-1)" "unprognostic (1.85e-1)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 191.0;Basal keratinocytes: 282.8;Basal respiratory cells: 137.6;Basal squamous epithelial cells: 174.8;granulocytes: 187.1;Squamous epithelial cells: 272.6;Suprabasal keratinocytes: 166.8" "Cancer enhanced" "Detected in many" "prostate cancer: 9.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 50.9" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075322 Uncertain Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" 18 Cytosol "HPA075322: " "unprognostic (2.28e-2)" "unprognostic (1.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (9.35e-3)" "unprognostic (5.54e-2)" "unprognostic (2.34e-1)" "unprognostic (9.85e-2)" "unprognostic (3.17e-2)" "unprognostic (2.23e-1)" "prognostic favorable (3.15e-9)" "unprognostic (1.55e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (7.65e-2)" ADRB3 ENSG00000188778 "Adrenoceptor beta 3" P13945 8 37962990-37966599 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 3.9;ovary: 11.3;urinary bladder: 4.5" "Cell type enriched" "Detected in some" 8 "Ovarian stromal cells: 14.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 169 "Bone cancer: 17.7" "Breast - Adipocytes (Breast), Prostate - Fibroblasts" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA061969 Uncertain NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 50: Connective tissue cells - ECM organization" "HPA061969: AB_2732674" "unprognostic (1.70e-1)" "unprognostic (2.24e-1)" "unprognostic (6.64e-3)" "unprognostic (5.41e-1)" "unprognostic (1.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-2)" "unprognostic (2.29e-8)" "unprognostic (1.10e-3)" "unprognostic (2.81e-2)" "unprognostic (5.37e-2)" "unprognostic (6.06e-3)" AGTR1 "AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R" ENSG00000144891 "Angiotensin II receptor type 1" P30556 3 148697784-148743008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 93.7;placenta: 137.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 44.5;Hepatocytes: 28.4;Leydig cells: 139.1;Sertoli cells: 51.7;Smooth muscle cells: 57.7" "Group enriched" "Detected in many" 8 "breast cancer: 9.6;liver cancer: 9.8;prostate cancer: 6.8;renal cancer: 2.8" "Region enriched" "Detected in many" 4 "midbrain: 17.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 9.3;Rhabdoid: 6.8" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003596 Enhanced Uncertain Vesicles NA NA "Cluster 11: Liver - Plasma proteins" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" 5 Vesicles "HPA003596: AB_1845163" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (8.78e-2)" "unprognostic (2.48e-4)" "unprognostic (5.28e-3)" "unprognostic (1.55e-1)" "unprognostic (3.46e-1)" "unprognostic (1.28e-2)" "unprognostic (3.26e-2)" "unprognostic (3.08e-2)" "unprognostic (9.25e-3)" "unprognostic (4.11e-2)" "unprognostic (4.79e-2)" "unprognostic (3.21e-3)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (5.41e-3)" AGTR2 "AT2, MRX88" ENSG00000180772 "Angiotensin II receptor type 2" P50052 X 116170744-116174974 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "endometrium 1: 8.5;lung: 8.6;smooth muscle: 12.7" "Cell type enriched" "Detected in some" 6 "Alveolar cells type 2: 14.6" "Group enriched" "Detected in some" 12 "endometrial cancer: 3.0;lung cancer: 1.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Sarcoma: 1.6" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 9 "cerebellum: 2.6" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 72: Alveolar cells - Lung function" 1 "unprognostic (2.13e-1)" "unprognostic (1.71e-1)" "unprognostic (3.22e-2)" "unprognostic (4.37e-2)" APLNR "AGTRL1, APJ, APJR, FLJ90771" ENSG00000134817 "Apelin receptor" P35414 11 57233577-57237250 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Gastrulation, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 78.6;lymphoid tissue: 105.0;placenta: 89.7" "Group enriched" "Detected in some" 8 "Adipocytes: 67.1;Endothelial cells: 42.4" "Cancer enhanced" "Detected in all" "glioma: 50.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 24.1" "Skin - Fibroblast_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" CAB025842 Approved NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "CAB025842: " "unprognostic (5.06e-2)" "unprognostic (3.56e-1)" "unprognostic (2.70e-2)" "unprognostic (1.00e-1)" "unprognostic (2.79e-1)" "unprognostic (6.68e-3)" "unprognostic (1.32e-2)" "unprognostic (2.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (4.72e-1)" "unprognostic (1.77e-3)" "unprognostic (3.27e-2)" "unprognostic (8.13e-2)" "unprognostic (1.13e-1)" "unprognostic (7.13e-3)" AVPR1A AVPR1 ENSG00000166148 "Arginine vasopressin receptor 1A" P37288 12 63142759-63151201 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 54.9" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 22.5;Hepatocytes: 49.2;Sertoli cells: 27.2;Smooth muscle cells: 121.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.8;Neuroblastoma: 1.1" "Breast - Endothelial cells, Liver - Hepatocytes" "Group enriched" "Detected in some" 5 "basal ganglia: 7.0;hypothalamus: 3.8" "Low region specificity" "Detected in all" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "unprognostic (1.49e-1)" "unprognostic (2.82e-1)" "unprognostic (9.90e-3)" "unprognostic (2.90e-1)" "unprognostic (1.59e-1)" "unprognostic (1.43e-3)" "unprognostic (3.79e-2)" "unprognostic (2.60e-1)" "unprognostic (3.58e-6)" "unprognostic (1.45e-1)" "unprognostic (7.29e-2)" "unprognostic (1.55e-1)" "unprognostic (1.38e-3)" "unprognostic (4.65e-3)" "unprognostic (1.25e-1)" "unprognostic (4.77e-2)" "unprognostic (4.66e-4)" AVPR1B "AVPR3, V1bR, VPR3" ENSG00000198049 "Arginine vasopressin receptor 1B" P47901 1 206106936-206117699 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "pituitary gland: 6.6" "Group enriched" "Detected in some" 21 "Enteroendocrine cells: 10.6;Glandular and luminal cells: 2.7" "Cancer enhanced" "Detected in some" "renal cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA075404 Enhanced NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 20: Enteroendocrine cells - Hormone signaling" "HPA075404: AB_2732291" "unprognostic (4.87e-2)" "unprognostic (1.44e-1)" "unprognostic (4.82e-1)" "unprognostic (2.82e-1)" "unprognostic (2.87e-1)" "unprognostic (1.08e-2)" "unprognostic (3.33e-1)" "unprognostic (2.96e-2)" "unprognostic (6.23e-2)" "unprognostic (7.65e-2)" "unprognostic (1.86e-1)" "unprognostic (6.66e-3)" AVPR2 "DIR, DIR3, V2R" ENSG00000126895 "Arginine vasopressin receptor 2" P30518 X 153902531-153907166 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes insipidus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.6;kidney: 10.7" "Group enriched" "Detected in some" 7 "Adipocytes: 46.0;Collecting duct cells: 40.8;Endothelial cells: 17.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 5 "cerebellum: 9.3" "Group enriched" "Detected in some" 28 "intermediate monocyte: 3.5;non-classical monocyte: 3.2" "Lineage enriched" "Detected in single" 30 "monocytes: 3.5" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 5.3" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Prostate - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 29 "cerebellum: 10.5" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 70: DU4475 - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 2 "unprognostic (3.05e-2)" "unprognostic (5.62e-2)" "unprognostic (1.99e-4)" "unprognostic (2.50e-4)" "unprognostic (2.76e-1)" "unprognostic (7.10e-6)" "unprognostic (3.80e-3)" "unprognostic (1.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.56e-2)" "unprognostic (4.21e-2)" "unprognostic (1.91e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-2)" "unprognostic (1.87e-1)" "unprognostic (4.38e-1)" "unprognostic (9.83e-2)" BDKRB1 "B1BKR, BKR1, bradyb1" ENSG00000100739 "Bradykinin receptor B1" P46663 14 96256210-96268967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 22.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 36.0;Basal squamous epithelial cells: 29.9;Mesothelial cells: 25.2;Squamous epithelial cells: 20.4;Suprabasal keratinocytes: 23.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in single" HPA002935 Approved NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA002935: AB_1078274" "unprognostic (6.15e-2)" "unprognostic (2.78e-2)" "unprognostic (9.40e-2)" "unprognostic (3.06e-3)" "unprognostic (6.76e-2)" "unprognostic (1.11e-2)" "unprognostic (3.31e-2)" "unprognostic (2.34e-3)" "unprognostic (2.23e-2)" "unprognostic (2.96e-2)" "unprognostic (4.80e-3)" "unprognostic (2.36e-1)" "unprognostic (9.96e-6)" "unprognostic (2.33e-1)" "unprognostic (8.82e-2)" "unprognostic (2.33e-3)" "unprognostic (4.66e-2)" BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 39.6" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 16.0;Endothelial cells: 16.7;Fibroblasts: 17.0;Ionocytes: 16.2;Langerhans cells: 19.0;Squamous epithelial cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 18.2" "Kidney - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" BRS3 "BB3, BB3R, BBR3" ENSG00000102239 "Bombesin receptor subtype 3" P32247 X 136487947-136493780 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "epididymis: 25.1" "Cell type enhanced" "Detected in some" "Pancreatic endocrine cells: 5.1;Spermatogonia: 1.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Region enriched" "Detected in some" 4 "hypothalamus: 6.1" "Region enhanced" "Detected in single" "basal ganglia: 2.4" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 45: Non-specific - Mixed function" "unprognostic (1.49e-1)" "unprognostic (1.31e-1)" "unprognostic (2.07e-1)" "unprognostic (1.79e-2)" "unprognostic (3.73e-6)" "unprognostic (1.59e-1)" "unprognostic (1.86e-1)" "unprognostic (5.59e-2)" C3AR1 "AZ3B, C3AR" ENSG00000171860 "Complement C3a receptor 1" Q16581 12 8056844-8066359 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 39.0" "Group enriched" "Detected in many" 5 "granulocytes: 59.3;Hofbauer cells: 171.3;Kupffer cells: 155.4;Macrophages: 151.8;monocytes: 176.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 902.8;eosinophil: 452.5;intermediate monocyte: 274.2;non-classical monocyte: 373.1" "Group enriched" "Detected in many" 20 "granulocytes: 902.8;monocytes: 373.1" "Cancer enhanced" "Detected in some" "Leukemia: 5.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" CAB009405 Enhanced NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" "CAB009405: AB_2066739" "unprognostic (1.11e-2)" "unprognostic (5.67e-2)" "unprognostic (5.06e-2)" "unprognostic (4.14e-2)" "unprognostic (6.60e-2)" "unprognostic (1.50e-1)" "unprognostic (4.81e-2)" "unprognostic (2.78e-1)" "unprognostic (6.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-2)" "unprognostic (8.22e-2)" "unprognostic (4.96e-2)" "unprognostic (9.24e-3)" "unprognostic (2.09e-2)" "unprognostic (8.16e-2)" C5AR1 "C5A, C5AR, C5R1, CD88" ENSG00000197405 "Complement C5a receptor 1" P21730 19 47290023-47322066 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 124.0;lymphoid tissue: 82.5" "Cell type enriched" "Detected in many" 7 "monocytes: 3492.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 393.7" "Group enriched" "Detected in many" 42 "granulocytes: 393.7;monocytes: 116.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Breast - Macrophages, Colon - Neutrophils, Heart muscle - Macrophages, Kidney - Macrophages" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "CAB002720, HPA014520, HPA048012" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 29: Monocytes - Innate immune response" "Golgi apparatus" Vesicles "CAB002720: , HPA014520: AB_1846337, HPA048012: " "unprognostic (5.95e-2)" "prognostic favorable (4.71e-4)" "unprognostic (1.70e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-2)" "unprognostic (1.11e-1)" "unprognostic (1.80e-2)" "unprognostic (4.41e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (9.55e-4)" "unprognostic (2.02e-1)" "unprognostic (9.56e-2)" "prognostic unfavorable (1.16e-4)" "unprognostic (1.96e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (1.82e-2)" "unprognostic (6.54e-2)" C5AR2 "C5L2, GPR77" ENSG00000134830 "Complement C5a receptor 2" Q9P296 19 47332175-47347329 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 13.8" "Cell type enriched" "Detected in many" 5 "monocytes: 266.2" "Cancer enhanced" "Detected in many" "breast cancer: 3.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 17.8;eosinophil: 11.9;neutrophil: 33.1" "Lineage enriched" "Detected in many" 7 "granulocytes: 33.1" "Cancer enhanced" "Detected in some" "breast cancer: 5.6;Leukemia: 3.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA016629 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Monocytes - Innate immune response" 1 "HPA016629: AB_1849312" "unprognostic (5.00e-2)" "unprognostic (2.31e-2)" "unprognostic (4.33e-2)" "unprognostic (2.00e-6)" "unprognostic (2.88e-1)" "unprognostic (1.13e-2)" "unprognostic (1.02e-2)" "unprognostic (2.13e-1)" "unprognostic (2.25e-2)" "unprognostic (1.28e-1)" "unprognostic (1.39e-2)" "unprognostic (6.05e-2)" "unprognostic (3.73e-5)" "unprognostic (1.16e-2)" "unprognostic (7.42e-2)" "unprognostic (1.34e-1)" "unprognostic (6.88e-3)" CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 68.3;lung: 74.4" "Cell type enhanced" "Detected in many" "Adipocytes: 131.7;Endometrial stromal cells: 98.4;Endothelial cells: 262.9;Lymphatic endothelial cells: 297.8;Oligodendrocyte precursor cells: 275.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 12.7;Sarcoma: 23.1" "Colon - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 3 "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" CASR "FHH, GPRC2A, HHC, HHC1, NSHPT" ENSG00000036828 "Calcium sensing receptor" P41180 3 122183668-122291629 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 29 "parathyroid gland: 633.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 47.7;Distal tubular cells: 6.1;Ductal cells: 5.3;Enteroendocrine cells: 11.8;Pancreatic endocrine cells: 17.0" "Cancer enriched" "Detected in some" 7 "pancreatic cancer: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "thyroid cancer: 7.0" "Kidney - Ascending Loop of Henle cells, Stomach - Gastric enteroendocrine cells, Thyroid - Parafollicular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA039686, HPA050335" Enhanced NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "HPA039686: AB_10673536, HPA050335: AB_2681092" "unprognostic (1.97e-2)" "unprognostic (7.40e-2)" "unprognostic (8.20e-4)" "unprognostic (3.15e-1)" "unprognostic (8.55e-4)" "unprognostic (1.58e-1)" "unprognostic (7.32e-2)" "unprognostic (7.67e-2)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (1.91e-5)" "unprognostic (2.72e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-2)" CCKAR ENSG00000163394 "Cholecystokinin A receptor" P32238 4 26481396-26490484 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "gallbladder: 28.2;stomach 1: 16.1" "Cell type enhanced" "Detected in single" "Gastric mucus-secreting cells: 1.8" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Group enriched" "Detected in many" 5 "hypothalamus: 11.0;midbrain: 14.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 4.3;liver cancer: 2.0;Neuroblastoma: 7.5" "Stomach - Chief cells" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Region enhanced" "Detected in many" "midbrain: 16.5" HPA073900 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 46: Gastric mucus-secreting cells - Digestion" "Plasma membrane, Cytosol" Nucleoplasm "HPA073900: " "unprognostic (7.48e-2)" "unprognostic (3.70e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-2)" "unprognostic (3.36e-1)" "unprognostic (3.79e-1)" CCKBR ENSG00000110148 "Cholecystokinin B receptor" P32239 11 6259806-6272127 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 31 "brain: 20.8;pancreas: 26.2;stomach 1: 40.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 14.1;Gastric mucus-secreting cells: 15.3;Granulosa cells: 17.1;Inhibitory neurons: 3.9" "Cancer enriched" "Detected in some" 8 "testis cancer: 9.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Rhabdoid: 2.5;testis cancer: 9.7" "Stomach - Parietal cells" "Low region specificity" "Detected in many" HPA079548 Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 53: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 Vesicles "Plasma membrane" "HPA079548: " "unprognostic (2.82e-1)" "unprognostic (4.62e-2)" "unprognostic (1.79e-3)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (6.34e-4)" "unprognostic (8.01e-2)" "unprognostic (3.01e-2)" "unprognostic (9.00e-2)" "unprognostic (3.30e-2)" "unprognostic (2.06e-1)" "unprognostic (2.92e-1)" "unprognostic (1.30e-2)" CCR1 "CD191, CKR-1, CMKBR1, MIP1aR, SCYAR1" ENSG00000163823 "C-C motif chemokine receptor 1" P32246 3 46201711-46208313 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 41.4" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 95.7;Hofbauer cells: 120.2;Kupffer cells: 154.3;Macrophages: 88.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 7 "Myeloma: 57.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 58: Macrophages - Innate immune response" 5 "unprognostic (3.95e-1)" "unprognostic (2.17e-1)" "unprognostic (1.20e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-1)" "unprognostic (6.66e-2)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (4.91e-3)" "unprognostic (2.20e-3)" "unprognostic (1.09e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (1.08e-1)" "unprognostic (5.52e-3)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" CCR10 GPR2 ENSG00000184451 "C-C motif chemokine receptor 10" P46092 17 42678889-42683917 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.7" "Cell type enriched" "Detected in many" 6 "Plasma cells: 99.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "plasmacytoid DC: 24.7;T-reg: 72.6" "Group enriched" "Detected in many" 8 "dendritic cells: 24.7;T-cells: 72.6" "Cancer enriched" "Detected in many" 4 "Myeloma: 42.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB011684, HPA048007, HPA069188" Uncertain Supported "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 66: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" 2 "Endoplasmic reticulum" "CAB011684: AB_731502, HPA048007: AB_2680232, HPA069188: AB_2686100" "unprognostic (3.25e-2)" "unprognostic (2.71e-2)" "unprognostic (5.70e-2)" "unprognostic (2.41e-2)" "unprognostic (5.25e-2)" "unprognostic (2.23e-3)" "unprognostic (5.18e-4)" "unprognostic (1.15e-1)" "unprognostic (9.55e-2)" "unprognostic (1.56e-1)" "unprognostic (1.21e-3)" "unprognostic (1.01e-2)" "unprognostic (2.32e-11)" "unprognostic (2.84e-2)" "unprognostic (1.53e-1)" "unprognostic (1.88e-2)" "unprognostic (1.87e-1)" CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353864-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.8" "Group enriched" "Detected in some" 4 "dendritic cells: 60.6;Kupffer cells: 47.0;Langerhans cells: 16.5;Macrophages: 21.7;Plasma cells: 31.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 557.4" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Myeloma: 29.9" "Breast - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 29: Monocytes - Innate immune response" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" CCR3 "CC-CKR-3, CD193, CKR3, CMKBR3" ENSG00000183625 "C-C motif chemokine receptor 3" P51677 3 46130890-46266706 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.5;skeletal muscle: 1.7" "Cell type enriched" "Detected in some" 8 "Oocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "basophil: 3400.3;eosinophil: 2516.4" "Lineage enriched" "Detected in many" 109 "granulocytes: 3400.3" "Cancer enriched" "Detected in single" 4 "Myeloma: 3.2" "Not detected" "Not detected" "CAB003795, HPA069514" Uncertain Approved "Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Small intestine - Absorption" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 74: Neutrophils - Degranulation" "Plasma membrane" "CAB003795: AB_562259, HPA069514: " "unprognostic (1.56e-2)" "unprognostic (6.65e-3)" "unprognostic (1.01e-1)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (3.25e-3)" "unprognostic (3.11e-7)" "unprognostic (4.36e-2)" "unprognostic (3.35e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (3.94e-2)" "unprognostic (3.17e-6)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (2.41e-1)" "unprognostic (9.81e-2)" CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 12.6;urinary bladder: 5.2" "Cell type enriched" "Detected in some" 5 "T-cells: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.8" "Lineage enriched" "Detected in many" 41 "T-cells: 60.8" "Cancer enriched" "Detected in some" 4 "lymphoma: 18.7" "Adipose subcutaneous - T-cells, Breast - T-cells, Skin - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 1 "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" CCR5 "CC-CKR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22" ENSG00000160791 "C-C motif chemokine receptor 5" P51681 3 46370946-46376206 "CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Diabetes mellitus, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.0" "Cell type enhanced" "Detected in some" "Kupffer cells: 7.3;Langerhans cells: 40.9;Macrophages: 14.3;T-cells: 13.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 40.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "lymphoma: 1.5;Myeloma: 1.2" "Lung - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells" "Low region specificity" "Detected in all" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Monocytes - Innate immune response" 6 "unprognostic (4.32e-3)" "unprognostic (1.94e-3)" "unprognostic (1.89e-3)" "prognostic favorable (7.42e-5)" "unprognostic (1.80e-2)" "prognostic favorable (9.33e-5)" "unprognostic (3.38e-3)" "unprognostic (9.90e-3)" "unprognostic (7.65e-2)" "unprognostic (6.22e-2)" "unprognostic (1.36e-1)" "unprognostic (5.34e-2)" "unprognostic (1.14e-3)" "unprognostic (8.34e-2)" "unprognostic (4.69e-2)" "unprognostic (3.14e-2)" "unprognostic (2.42e-2)" CCR6 "BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22" ENSG00000112486 "C-C motif chemokine receptor 6" P51684 6 167111807-167139141 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 32.9" "Group enriched" "Detected in some" 6 "B-cells: 15.7;T-cells: 13.7" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "MAIT T-cell: 70.3;memory B-cell: 64.1;memory CD4 T-cell: 27.4;naive B-cell: 73.4;T-reg: 52.1" "Group enriched" "Detected in many" 5 "B-cells: 73.4;T-cells: 70.3" "Cancer enhanced" "Detected in some" "liver cancer: 5.2" "Adipose subcutaneous - T-cells, Prostate - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 7 "basal ganglia: 1.8" "Not detected" "Not detected" "CAB006820, HPA014488" Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 7: T-cells - T-cell receptor" "CAB006820: , HPA014488: AB_1846639" "unprognostic (1.12e-2)" "unprognostic (2.92e-2)" "unprognostic (2.07e-3)" "unprognostic (2.08e-1)" "unprognostic (8.43e-2)" "unprognostic (2.05e-4)" "unprognostic (2.39e-1)" "unprognostic (4.98e-3)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (4.19e-2)" "unprognostic (4.26e-2)" "unprognostic (2.68e-4)" "unprognostic (3.74e-2)" "unprognostic (7.96e-2)" "unprognostic (2.26e-1)" "unprognostic (1.77e-1)" CCR7 "BLR2, CD197, CDw197, CMKBR7, EBI1" ENSG00000126353 "C-C motif chemokine receptor 7" P32248 17 40553769-40565472 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;lymphoid tissue: 82.0" "Cell type enhanced" "Detected in some" "B-cells: 167.8;Cytotrophoblasts: 150.8;Langerhans cells: 549.3;Syncytiotrophoblasts: 515.0;T-cells: 89.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "naive CD4 T-cell: 4611.8" "Lineage enriched" "Detected in all" 4 "T-cells: 4611.8" "Cancer enriched" "Detected in some" 7 "lymphoma: 140.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB003796, HPA031383, HPA074467" Enhanced Enhanced Mitochondria NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 11: White matter - Signal transduction" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 14: Langerhans cells - Innate immune response" Mitochondria "CAB003796: AB_562261, HPA031383: AB_2673854, HPA074467: AB_2686693" "prognostic favorable (3.84e-4)" "prognostic favorable (8.03e-6)" "unprognostic (2.26e-3)" "unprognostic (1.32e-3)" "unprognostic (2.35e-3)" "prognostic favorable (7.61e-7)" "unprognostic (2.71e-4)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "unprognostic (4.68e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-1)" "unprognostic (1.08e-3)" "unprognostic (3.12e-1)" "prognostic unfavorable (7.72e-4)" "unprognostic (1.02e-1)" "unprognostic (7.95e-2)" CCR8 "CDw198, CKR-L1, CMKBR8, CMKBRL2, CY6, GPR-CY6, TER1" ENSG00000179934 "C-C motif chemokine receptor 8" P51685 3 39329709-39333680 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 7.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 6 "T-reg: 25.8" "Lineage enriched" "Detected in single" 32 "T-cells: 25.8" "Group enriched" "Detected in some" 8 "Leukemia: 2.9;lymphoma: 4.4;testis cancer: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA042383 Enhanced NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 71: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA042383: AB_2732497" "unprognostic (2.16e-1)" "unprognostic (2.12e-2)" "unprognostic (2.91e-2)" "unprognostic (1.04e-1)" "unprognostic (2.38e-2)" "unprognostic (7.63e-4)" "unprognostic (3.31e-1)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (3.37e-2)" "unprognostic (7.40e-2)" "unprognostic (2.99e-1)" "unprognostic (4.65e-8)" "unprognostic (7.96e-2)" "unprognostic (2.24e-2)" "unprognostic (2.56e-1)" "unprognostic (4.14e-1)" CCR9 "CDw199, GPR-9-6, GPR28" ENSG00000173585 "C-C motif chemokine receptor 9" P51686 3 45884425-45903174 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "lymphoid tissue: 126.5" "Group enriched" "Detected in some" 5 "B-cells: 1.2;T-cells: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "memory B-cell: 24.3;naive B-cell: 15.7;T-reg: 8.2" "Group enriched" "Detected in many" 43 "B-cells: 24.3;T-cells: 8.2" "Cancer enriched" "Detected in single" 8 "Leukemia: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB006839, HPA066879" Uncertain Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 71: Thymus - Adaptive immune response" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "Plasma membrane" "Endoplasmic reticulum" "CAB006839: , HPA066879: " "unprognostic (3.08e-3)" "unprognostic (3.37e-1)" "unprognostic (5.56e-2)" "unprognostic (1.78e-1)" "unprognostic (8.65e-3)" "unprognostic (7.88e-3)" "unprognostic (4.54e-1)" "unprognostic (2.94e-2)" "unprognostic (3.00e-1)" "unprognostic (1.77e-1)" "unprognostic (8.06e-2)" "unprognostic (1.16e-1)" "unprognostic (2.59e-2)" "unprognostic (1.88e-1)" "unprognostic (4.34e-1)" "unprognostic (2.27e-1)" "unprognostic (7.20e-3)" CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 36.3;Hofbauer cells: 49.8;Langerhans cells: 44.8;Macrophages: 61.6;monocytes: 179.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043238 Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Small intestine - Absorption" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" "HPA043238: AB_10794924" "unprognostic (3.94e-1)" "unprognostic (7.02e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.64e-1)" "unprognostic (2.67e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.62e-1)" "unprognostic (4.10e-2)" "unprognostic (4.17e-2)" "unprognostic (9.73e-2)" "unprognostic (1.98e-2)" "unprognostic (5.17e-2)" "unprognostic (1.78e-1)" "unprognostic (3.04e-2)" "unprognostic (2.57e-1)" "prognostic favorable (9.67e-5)" CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 30.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 29.1;Basal respiratory cells: 28.6;Ciliated cells: 56.5;Club cells: 31.1;Glandular and luminal cells: 35.4;Ionocytes: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA 280000 "Cluster 34: B-cells - Unknown function" "Cluster 13: Skin - Cornification" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Respiratory epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" CELSR2 "ADGRC2, CDHF10, EGFL2, Flamingo1, KIAA0279, MEGF3" ENSG00000143126 "Cadherin EGF LAG seven-pass G-type receptor 2" Q9HCU4 1 109249539-109275751 "G-protein coupled receptors, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.2;skin 1: 24.1" "Cell type enhanced" "Detected in many" "Horizontal cells: 50.4;Oligodendrocytes: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013952 Uncertain Approved Cytosol NA NA 1300000 "Cluster 80: Non-specific - Endocytosis" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Squamous epithelial cells - Keratinization" Cytosol "HPA013952: AB_1846518" "unprognostic (4.46e-3)" "unprognostic (1.07e-2)" "unprognostic (3.00e-2)" "unprognostic (4.71e-2)" "unprognostic (2.19e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-2)" "unprognostic (2.98e-1)" "unprognostic (1.33e-1)" "unprognostic (1.59e-2)" "unprognostic (1.47e-2)" "unprognostic (1.51e-1)" "unprognostic (1.94e-2)" "unprognostic (1.39e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-2)" CELSR3 "ADGRC3, CDHF11, EGFL1, FMI1, HFMI1, MEGF2" ENSG00000008300 "Cadherin EGF LAG seven-pass G-type receptor 3" Q9NYQ7 3 48636463-48662886 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.7;pituitary gland: 7.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 14.1;Cone photoreceptor cells: 22.1;Excitatory neurons: 9.8;Horizontal cells: 20.8;Inhibitory neurons: 10.3;Rod photoreceptor cells: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062866 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA062866: AB_2684886" "unprognostic (7.80e-2)" "unprognostic (3.80e-2)" "unprognostic (4.89e-1)" "unprognostic (9.12e-4)" "unprognostic (1.51e-1)" "unprognostic (1.59e-6)" "unprognostic (3.61e-6)" "unprognostic (1.86e-1)" "unprognostic (1.46e-3)" "unprognostic (5.07e-2)" "unprognostic (2.13e-3)" "unprognostic (2.87e-3)" "unprognostic (3.26e-3)" "unprognostic (9.53e-2)" "unprognostic (1.42e-1)" "unprognostic (3.86e-2)" "unprognostic (1.73e-1)" CHRM1 ENSG00000168539 "Cholinergic receptor muscarinic 1" P11229 11 62908679-62921807 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "brain: 44.0;prostate: 28.7;salivary gland: 28.0" "Cell type enriched" "Detected in some" 5 "Prostatic glandular cells: 48.9" "Cancer enriched" "Detected in some" 16 "prostate cancer: 27.9" "Group enriched" "Detected in many" 5 "amygdala: 42.4;basal ganglia: 59.5;cerebral cortex: 69.7;hippocampal formation: 63.2;white matter: 36.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "breast cancer: 3.4;Neuroblastoma: 8.7;prostate cancer: 2.5" "Breast - Breast glandular cells (progenitors), Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in many" HPA014101 Enhanced Supported NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 40: Prostatic glandular cells - Transcription" "HPA014101: AB_1854210" "unprognostic (3.19e-2)" "unprognostic (2.14e-1)" "unprognostic (2.25e-1)" "unprognostic (1.31e-2)" "unprognostic (7.94e-2)" "unprognostic (2.29e-1)" "unprognostic (1.16e-2)" "unprognostic (2.89e-2)" "unprognostic (1.91e-1)" "unprognostic (2.76e-1)" "unprognostic (2.08e-1)" "unprognostic (8.57e-4)" "unprognostic (4.88e-1)" "unprognostic (6.43e-2)" "unprognostic (1.75e-1)" CHRM2 ENSG00000181072 "Cholinergic receptor muscarinic 2" P08172 7 136868652-137020255 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 34.9;intestine: 20.5" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 71.7;Excitatory neurons: 47.5;Inhibitory neurons: 113.6" "Cancer enhanced" "Detected in single" "stomach cancer: 0.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 11.0" "Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB022338, HPA029795" Approved NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Neurons - Neuronal signaling" "CAB022338: , HPA029795: AB_10601357" "unprognostic (3.51e-2)" "unprognostic (3.73e-4)" "unprognostic (5.77e-2)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (4.00e-1)" "unprognostic (2.69e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-1)" "unprognostic (1.35e-3)" CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.0" "Group enriched" "Detected in many" 4 "Excitatory neurons: 776.4;Inhibitory neurons: 594.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 8.4" "Heart muscle - Smooth muscle cells, Skin - Eccrine sweat gland cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" 1 "Plasma membrane" "HPA024106: AB_1854211, HPA048036: AB_2680238" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46383789-46391776 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.0;intestine: 5.9;lymphoid tissue: 14.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "basal ganglia: 44.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 22.1" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 77: Plasma cells - Protein processing" 2 "Golgi apparatus" Nucleoplasm "CAB022444: , HPA072083: " "unprognostic (7.11e-2)" "unprognostic (3.79e-1)" "unprognostic (5.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.63e-3)" "unprognostic (1.38e-1)" "unprognostic (6.02e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (2.96e-3)" "unprognostic (4.08e-3)" "unprognostic (5.02e-2)" "unprognostic (3.83e-2)" "unprognostic (3.64e-1)" "unprognostic (1.71e-1)" "unprognostic (3.56e-1)" "unprognostic (5.08e-2)" CHRM5 ENSG00000184984 "Cholinergic receptor muscarinic 5" P08912 15 33968497-34067458 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 8.7" "Cell type enriched" "Detected in some" 7 "Oligodendrocytes: 166.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in many" "hypothalamus: 13.2" "Low region specificity" "Detected in many" HPA013172 Uncertain NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 51: Oligodendrocytes - Unknown function" 1 "HPA013172: AB_1854212" "unprognostic (8.19e-2)" "unprognostic (2.13e-1)" "unprognostic (7.67e-2)" "unprognostic (4.32e-1)" "unprognostic (3.05e-3)" "unprognostic (2.77e-1)" "unprognostic (2.49e-2)" "unprognostic (2.79e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-2)" "unprognostic (4.61e-4)" "unprognostic (7.95e-2)" "unprognostic (1.33e-6)" "unprognostic (1.42e-1)" "unprognostic (4.53e-2)" "unprognostic (1.38e-1)" "unprognostic (9.07e-2)" CMKLR1 RVER1 ENSG00000174600 "Chemerin chemokine-like receptor 1" Q99788 12 108288044-108339317 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33.4" "Cell type enhanced" "Detected in some" "dendritic cells: 18.6;Hofbauer cells: 28.9;Kupffer cells: 51.1;Macrophages: 29.6;Microglial cells: 37.6;NK-cells: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 14.6;plasmacytoid DC: 18.2" "Group enriched" "Detected in many" 22 "dendritic cells: 18.2;monocytes: 14.6;T-cells: 7.1" "Low cancer specificity" "Detected in some" "Breast - Macrophages, Heart muscle - Fibroblasts, Liver - Kupffer cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047865 Uncertain NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 70: DU4475 - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA047865: AB_2680191" "unprognostic (1.78e-1)" "unprognostic (2.61e-2)" "unprognostic (8.83e-3)" "unprognostic (7.39e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-3)" "unprognostic (1.69e-1)" "unprognostic (2.94e-2)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (1.06e-1)" "unprognostic (8.72e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (5.19e-2)" "unprognostic (1.14e-1)" CMKLR2 GPR1 ENSG00000183671 "Chemerin chemokine-like receptor 2" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 32.4" "Cell type enhanced" "Detected in some" "Extravillous trophoblasts: 14.8;Granulosa cells: 6.3;Lymphatic endothelial cells: 26.1;Oocytes: 4.4;Ovarian stromal cells: 4.3" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Region enriched" "Detected in many" 12 "choroid plexus: 35.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Colon - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166347 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 22.3;pituitary gland: 20.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 22.0;Excitatory neurons: 43.1;Inhibitory neurons: 192.1;Sertoli cells: 49.0;Smooth muscle cells: 22.1" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 9.9;lymphoma: 15.1;thyroid cancer: 4.0" "Breast - Adipocytes (Breast), Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 69: Neurons - Neuronal signaling" 2 "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" CNR2 CB2 ENSG00000188822 "Cannabinoid receptor 2" P34972 1 23870515-23913362 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 3.3;lymphoid tissue: 8.6" "Cell type enriched" "Detected in some" 4 "B-cells: 35.2" "Cancer enriched" "Detected in single" 6 "testis cancer: 2.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "basophil: 49.2;eosinophil: 35.1;memory B-cell: 29.6;naive B-cell: 27.9;NK-cell: 19.4" "Group enriched" "Detected in many" 9 "B-cells: 29.6;granulocytes: 49.2;NK-cells: 19.4" "Group enriched" "Detected in some" 14 "Leukemia: 3.1;lymphoma: 6.3" "Lung - B-cells" "Not detected" "Not detected" "Not detected" "Not detected" CAB009719 Uncertain NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 22 "CAB009719: AB_2082784" "unprognostic (9.45e-4)" "unprognostic (5.40e-3)" "unprognostic (8.50e-3)" "unprognostic (8.19e-3)" "unprognostic (3.55e-3)" "unprognostic (9.34e-6)" "unprognostic (5.58e-3)" "unprognostic (6.96e-3)" "unprognostic (1.74e-1)" "unprognostic (7.87e-2)" "unprognostic (1.53e-1)" "unprognostic (4.93e-2)" "unprognostic (1.04e-3)" "unprognostic (3.67e-1)" "unprognostic (1.80e-1)" "unprognostic (3.75e-2)" "unprognostic (4.91e-2)" CRHR1 "CRF-R, CRF1, CRHR" ENSG00000120088 "Corticotropin releasing hormone receptor 1" P34998 17 45784277-45835828 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 19.5;pituitary gland: 19.8" "Cell type enriched" "Detected in single" 10 "Bipolar cells: 1.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025251 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" 1 "CAB025251: " "unprognostic (4.59e-2)" "unprognostic (1.43e-2)" "unprognostic (2.59e-7)" "unprognostic (1.76e-1)" "unprognostic (2.71e-1)" "unprognostic (3.94e-2)" "unprognostic (2.48e-1)" "unprognostic (4.55e-4)" "unprognostic (1.65e-2)" "unprognostic (2.21e-1)" "unprognostic (3.33e-4)" "unprognostic (2.07e-5)" "unprognostic (3.26e-1)" "unprognostic (1.49e-1)" "unprognostic (1.59e-1)" CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 21.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 8.0;Horizontal cells: 11.3;Inhibitory neurons: 4.7" "Not detected" "Not detected" "Region enhanced" "Detected in all" "choroid plexus: 48.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 5.5" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" Receptor NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" CX3CR1 "CCRL1, CMKBRL1, CMKDR1, GPR13, V28" ENSG00000168329 "C-X3-C motif chemokine receptor 1" P49238 3 39263495-39281735 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.3" "Cell type enhanced" "Detected in some" "Langerhans cells: 37.8;Macrophages: 46.2;Microglial cells: 169.1;NK-cells: 184.9" "Cancer enriched" "Detected in many" 4 "glioma: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 451.3" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 6 "Myeloma: 16.7" "Heart muscle - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032478, HPA046587" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane" "CAB032478: AB_638830, HPA046587: AB_2679708" "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.65e-1)" "unprognostic (2.42e-2)" "unprognostic (6.52e-2)" "unprognostic (3.01e-3)" "unprognostic (2.64e-1)" "unprognostic (1.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.57e-3)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (8.59e-2)" "unprognostic (7.71e-3)" "unprognostic (1.12e-1)" CXCR1 "CD181, CDw128a, CKR-1, CMKAR1, IL8RA" ENSG00000163464 "C-X-C motif chemokine receptor 1" P25024 2 218162841-218166962 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 12.7;lymphoid tissue: 39.5" "Group enriched" "Detected in some" 5 "NK-cells: 9.8;Serous glandular cells: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 14 "neutrophil: 1477.6" "Lineage enriched" "Detected in many" 62 "granulocytes: 1477.6" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" HPA031991 Uncertain NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 3 "HPA031991: AB_2674103" "unprognostic (2.80e-1)" "unprognostic (2.91e-2)" "unprognostic (3.53e-2)" "unprognostic (5.74e-2)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (2.14e-2)" "unprognostic (3.36e-2)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" "unprognostic (8.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.88e-1)" "unprognostic (5.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.4;lymphoid tissue: 42.2" "Cell type enhanced" "Detected in some" "NK-cells: 30.8;Serous glandular cells: 19.4;Squamous epithelial cells: 13.6;Suprabasal keratinocytes: 16.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3297.5" "Lineage enriched" "Detected in many" 109 "granulocytes: 3297.5" "Cancer enriched" "Detected in single" 9 "Leukemia: 6.9" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophil_2, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 11 "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" CXCR3 "CD183, CKR-L2, CMKAR3, GPR9, IP10-R, MigR" ENSG00000186810 "C-X-C motif chemokine receptor 3" P49682 X 71615916-71618511 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;intestine: 6.2;lymphoid tissue: 15.9" "Cell type enriched" "Detected in some" 8 "dendritic cells: 379.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 307.2" "Group enriched" "Detected in many" 5 "dendritic cells: 307.2;NK-cells: 199.6;T-cells: 124.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 3.3;lymphoma: 9.3;Myeloma: 3.7" "Adipose subcutaneous - T-cells, Colon - T-cells, Liver - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA045942 Enhanced NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" 3 "HPA045942: AB_2679507" "unprognostic (4.84e-3)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "prognostic favorable (3.44e-6)" "unprognostic (3.93e-2)" "prognostic favorable (3.35e-4)" "unprognostic (1.01e-2)" "unprognostic (5.24e-2)" "prognostic favorable (2.90e-4)" "unprognostic (6.32e-2)" "unprognostic (1.34e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.67e-6)" "unprognostic (4.67e-2)" "unprognostic (2.18e-1)" "unprognostic (2.91e-2)" "unprognostic (5.76e-2)" CXCR4 "CD184, D2S201E, fusin, HM89, HSY3RR, LESTR, NPY3R, NPYR, NPYY3R" ENSG00000121966 "C-X-C motif chemokine receptor 4" P61073 2 136114349-136119177 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 1229.2;lymphoid tissue: 543.2" "Cell type enhanced" "Detected in many" "B-cells: 1653.4;dendritic cells: 2147.0;monocytes: 2202.0;NK-cells: 1186.4;Schwann cells: 984.9;T-cells: 1749.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 190.2;lymphoma: 270.2;Myeloma: 151.1" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Skin - T-cells, Testis - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 8 "unprognostic (1.19e-1)" "unprognostic (1.46e-2)" "unprognostic (2.69e-1)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.12e-2)" "unprognostic (4.99e-2)" "unprognostic (9.25e-2)" "unprognostic (6.06e-2)" "prognostic favorable (2.05e-4)" "unprognostic (1.23e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.41e-7)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.57e-1)" "unprognostic (3.47e-2)" "unprognostic (9.33e-2)" CXCR5 "BLR1, CD185, MDR15" ENSG00000160683 "C-X-C motif chemokine receptor 5" P32302 11 118883892-118897787 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "B-cell activation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.3;intestine: 9.9;lymphoid tissue: 30.6" "Cell type enriched" "Detected in some" 14 "B-cells: 82.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "memory B-cell: 67.9;naive B-cell: 92.5" "Lineage enriched" "Detected in many" 8 "B-cells: 92.5" "Cancer enriched" "Detected in some" 12 "lymphoma: 36.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026149, HPA042432" Enhanced NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 73: B-cells - B-cell function" 1 "CAB026149: , HPA042432: AB_2677995" "unprognostic (8.51e-2)" "unprognostic (1.52e-2)" "unprognostic (1.68e-1)" "unprognostic (1.19e-1)" "unprognostic (4.02e-5)" "unprognostic (2.08e-2)" "unprognostic (3.23e-3)" "unprognostic (1.19e-2)" "unprognostic (3.66e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-5)" "unprognostic (4.21e-1)" "unprognostic (2.03e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" CXCR6 "BONZO, CD186, STRL33, TYMSTR" ENSG00000172215 "C-X-C motif chemokine receptor 6" O00574 3 45940933-45948351 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 16.6" "Group enriched" "Detected in some" 7 "Extravillous trophoblasts: 87.5;T-cells: 64.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 446.5" "Lineage enriched" "Detected in many" 5 "T-cells: 446.5" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.1" "Kidney - T-cells, Lung - T-cells, Pancreas - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "unprognostic (2.05e-3)" "prognostic favorable (4.92e-4)" "unprognostic (1.77e-3)" "prognostic favorable (6.74e-6)" "unprognostic (6.67e-2)" "prognostic favorable (2.16e-4)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (1.93e-2)" "unprognostic (3.65e-4)" "unprognostic (8.57e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (2.42e-5)" "unprognostic (2.25e-2)" "unprognostic (4.42e-2)" "unprognostic (3.46e-2)" "unprognostic (1.57e-2)" CYSLTR1 "CysLT(1), CysLT1, CYSLT1R" ENSG00000173198 "Cysteinyl leukotriene receptor 1" Q9Y271 X 78271468-78327691 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.3" "Cell type enhanced" "Detected in many" "Adipocytes: 27.2;B-cells: 61.7;dendritic cells: 68.2;granulocytes: 42.7;Hofbauer cells: 35.9;Kupffer cells: 28.7;Macrophages: 32.0;monocytes: 35.3;Plasma cells: 41.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 85.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 7.9;lymphoma: 3.5;Myeloma: 7.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA010546 Approved NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 73: B-cells - B-cell function" 1 "HPA010546: AB_1078268" "unprognostic (9.48e-2)" "unprognostic (6.01e-5)" "unprognostic (4.72e-3)" "unprognostic (3.04e-1)" "unprognostic (6.30e-2)" "unprognostic (2.80e-3)" "unprognostic (2.52e-1)" "unprognostic (8.19e-2)" "unprognostic (1.19e-1)" "unprognostic (2.53e-2)" "unprognostic (4.55e-1)" "unprognostic (2.43e-1)" "unprognostic (4.41e-4)" "unprognostic (5.82e-2)" "unprognostic (3.56e-2)" "unprognostic (9.87e-2)" "unprognostic (8.94e-2)" CYSLTR2 "CysLT(2), CYSLT2R" ENSG00000152207 "Cysteinyl leukotriene receptor 2" Q9NS75 13 48653711-48711226 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 22.2;seminal vesicle: 15.3" "Cell type enriched" "Detected in some" 4 "monocytes: 103.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.6;thyroid cancer: 7.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "eosinophil: 89.7" "Lineage enriched" "Detected in many" 14 "granulocytes: 89.7" "Cancer enhanced" "Detected in some" "Leukemia: 3.6;lymphoma: 3.1;Neuroblastoma: 2.9" HPA046528 Approved NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 7: Adipose tissue - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 29: Monocytes - Innate immune response" 4 "HPA046528: AB_2679687" "unprognostic (9.83e-3)" "unprognostic (2.72e-3)" "unprognostic (1.05e-2)" "unprognostic (6.81e-2)" "unprognostic (2.94e-2)" "unprognostic (3.11e-2)" "unprognostic (1.11e-1)" "unprognostic (7.41e-3)" "unprognostic (8.33e-2)" "unprognostic (1.83e-1)" "unprognostic (5.44e-2)" "unprognostic (5.93e-2)" "unprognostic (1.88e-3)" "unprognostic (3.79e-2)" "unprognostic (4.44e-2)" "unprognostic (2.35e-2)" "unprognostic (1.18e-2)" DRD1 ENSG00000184845 "Dopamine receptor D1" P21728 5 175440036-175444182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "brain: 25.9;retina: 8.2" "Group enriched" "Detected in some" 15 "Bipolar cells: 31.3;Horizontal cells: 42.2" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in many" 4 "basal ganglia: 46.6;cerebral cortex: 12.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.1;Bone cancer: 1.6" "Region enriched" "Detected in many" 9 "basal ganglia: 164.5" "Region enriched" "Detected in many" 13 "basal ganglia: 119.1" "HPA013393, HPA017304" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 4 "Plasma membrane" Cytosol "HPA013393: AB_1847833, HPA017304: " "unprognostic (2.74e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.15e-6)" "unprognostic (6.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (8.60e-4)" "unprognostic (5.86e-2)" "unprognostic (5.43e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" DRD2 ENSG00000149295 "Dopamine receptor D2" P14416 11 113409605-113475691 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 65.2;pituitary gland: 58.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 7.3;Horizontal cells: 15.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 163.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.6" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 10 "basal ganglia: 205.4" "Region enriched" "Detected in many" 4 "basal ganglia: 192.0" "HPA015139, HPA015691" Supported Supported NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 4 "HPA015139: , HPA015691: AB_1847834" "unprognostic (8.49e-2)" "unprognostic (2.11e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-4)" "unprognostic (2.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.97e-2)" "unprognostic (5.89e-2)" "unprognostic (4.40e-2)" "unprognostic (8.33e-4)" "unprognostic (1.10e-1)" "unprognostic (6.65e-3)" "unprognostic (2.29e-1)" "unprognostic (1.71e-1)" "unprognostic (4.82e-2)" "unprognostic (8.49e-3)" DRD3 ENSG00000151577 "Dopamine receptor D3" P35462 3 114127580-114199407 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 3.2" "Cell type enriched" "Detected in some" 6 "Late spermatids: 24.0" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Region enriched" "Detected in some" 5 "basal ganglia: 7.4" "Region enriched" "Detected in all" 9 "basal ganglia: 26.2" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Late spermatids - Spermatogenesis" "unprognostic (2.32e-1)" DRD4 ENSG00000069696 "Dopamine receptor D4" P21917 11 637269-640706 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 150.1;Cone photoreceptor cells: 171.6;dendritic cells: 41.2;Rod photoreceptor cells: 169.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062682 Uncertain "Plasma membrane,Centrosome" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 66: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 25: Bipolar cells - Visual perception" 6 "Plasma membrane" Centrosome "HPA062682: " "unprognostic (8.83e-2)" "unprognostic (2.99e-2)" "unprognostic (4.98e-4)" "unprognostic (3.81e-2)" "unprognostic (7.52e-2)" "unprognostic (7.89e-3)" "unprognostic (3.14e-2)" "unprognostic (2.96e-1)" "unprognostic (8.45e-2)" "unprognostic (5.07e-2)" "unprognostic (3.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.05e-4)" "unprognostic (1.26e-2)" "unprognostic (8.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-1)" DRD5 "DRD1B, DRD1L2" ENSG00000169676 "Dopamine receptor D5" P21918 4 9781634-9784009 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Dystonia, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.6;lymphoid tissue: 1.3;stomach 1: 4.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.1;Horizontal cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "thalamus: 9.1" HPA048930 Supported NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 65: Neurons - Synaptic function" 1 "HPA048930: AB_2680562" "unprognostic (2.03e-2)" "unprognostic (2.63e-1)" "unprognostic (9.73e-2)" "unprognostic (4.27e-2)" "unprognostic (4.44e-3)" "unprognostic (1.98e-2)" "unprognostic (1.32e-4)" "unprognostic (5.09e-4)" "unprognostic (6.51e-2)" "unprognostic (1.46e-1)" "unprognostic (7.36e-3)" EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 110.0" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 116.1;Leydig cells: 43.2;Ovarian stromal cells: 51.5;Peritubular cells: 66.9;Smooth muscle cells: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Smooth muscle cells, Liver - Hepatic stellate cells, Thyroid - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 48: Smooth muscle cells - Signal transduction" 2 "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 123.5" "Cell type enhanced" "Detected in many" "Adipocytes: 108.5;Astrocytes: 119.8;Endothelial cells: 74.1;Leydig cells: 82.0;Lymphatic endothelial cells: 93.3;Melanocytes: 173.5;Muller glia cells: 102.3;Sertoli cells: 103.3;Smooth muscle cells: 78.6" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 12 "Myeloma: 84.2;skin cancer: 130.7" "Liver - Hepatic stellate cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 54: Lymphatic endothelial cells - Lymph vessel development" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" F2R "CF2R, PAR-1, PAR1, TR" ENSG00000181104 "Coagulation factor II thrombin receptor" P25116 5 76716126-76735770 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 67.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 46.3;Endothelial cells: 52.1;Fibroblasts: 62.0;Lymphatic endothelial cells: 46.9;Mucus glandular cells: 41.6;NK-cells: 90.1;Smooth muscle cells: 41.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 25.5" "Group enriched" "Detected in many" 14 "NK-cells: 7.0;T-cells: 25.5" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008973, CAB012962" Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 47: Spleen - Immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 "CAB008973: , CAB012962: AB_2533198" "unprognostic (3.03e-1)" "unprognostic (7.76e-2)" "unprognostic (5.55e-2)" "unprognostic (7.76e-2)" "unprognostic (7.14e-2)" "unprognostic (3.46e-1)" "unprognostic (2.51e-1)" "unprognostic (3.75e-2)" "unprognostic (5.37e-2)" "unprognostic (1.36e-1)" "unprognostic (1.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (2.21e-7)" "unprognostic (2.72e-3)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (6.74e-3)" F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 57.4;stomach 1: 42.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 74.3;Distal enterocytes: 85.0;Gastric mucus-secreting cells: 74.3;Glandular and luminal cells: 66.8;Intestinal goblet cells: 51.9;Proximal enterocytes: 56.1;Suprabasal keratinocytes: 97.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 18.1" "Immune cell enhanced" "Detected in many" "neutrophil: 42.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.2" "Cancer enhanced" "Detected in many" "Bile duct cancer: 184.1" "Colon - Colon enterocytes, Heart muscle - Fibroblasts, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Glandular & Luminal cells - Unknown function" 7 "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" F2RL2 PAR3 ENSG00000164220 "Coagulation factor II thrombin receptor like 2" O00254 5 76615482-76623413 "G-protein coupled receptors, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 6.6" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 2.2;Fibroblasts: 4.2;NK-cells: 1.8;Pancreatic endocrine cells: 1.7;Rod photoreceptor cells: 4.6;Schwann cells: 7.4;Smooth muscle cells: 2.4" "Cancer enhanced" "Detected in many" "breast cancer: 9.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 10.3" "Lineage enriched" "Detected in many" 9 "granulocytes: 10.3" "Cancer enhanced" "Detected in many" "Rhabdoid: 36.3" "Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 26: Schwann cells & Melanocytes - Mixed function" 1 "unprognostic (1.35e-3)" "unprognostic (5.71e-3)" "prognostic favorable (4.69e-4)" "unprognostic (6.71e-2)" "unprognostic (4.16e-3)" "unprognostic (3.56e-2)" "unprognostic (9.71e-2)" "unprognostic (8.49e-2)" "unprognostic (3.78e-2)" "unprognostic (1.43e-1)" "unprognostic (1.14e-1)" "unprognostic (3.20e-1)" "unprognostic (2.24e-8)" "unprognostic (7.64e-2)" "unprognostic (8.98e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" F2RL3 PAR4 ENSG00000127533 "F2R like thrombin or trypsin receptor 3" Q96RI0 19 16888999-16892606 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 18.4;lung: 32.4;thyroid gland: 18.6" "Cell type enhanced" "Detected in some" "Adipocytes: 105.5;Endothelial cells: 24.6;Lymphatic endothelial cells: 28.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 10.6" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031401, HPA042340" Supported "Plasma membrane" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 7: Adipose tissue - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" "Plasma membrane" "HPA031401: , HPA042340: " "unprognostic (6.17e-2)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (3.83e-1)" "unprognostic (3.27e-1)" "unprognostic (8.31e-3)" "unprognostic (2.97e-1)" "unprognostic (3.28e-2)" "unprognostic (6.52e-2)" "unprognostic (2.60e-1)" "unprognostic (6.30e-2)" "unprognostic (3.00e-3)" "prognostic favorable (6.25e-4)" "unprognostic (2.37e-2)" "unprognostic (1.43e-1)" "unprognostic (3.53e-1)" "unprognostic (2.11e-2)" FFAR1 "FFA1R, GPR40" ENSG00000126266 "Free fatty acid receptor 1" O14842 19 35347902-35353864 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 3.0;brain: 2.3;ovary: 2.4;pancreas: 2.4" "Group enriched" "Detected in some" 4 "Enteroendocrine cells: 5.9;Granulosa cells: 4.6;Pancreatic endocrine cells: 6.8" "Cancer enriched" "Detected in single" 13 "pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Cancer enhanced" "Detected in single" "lymphoma: 1.3" "Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" HPA048933 Supported "Plasma membrane" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Plasma membrane" "HPA048933: " "unprognostic (9.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" "unprognostic (4.46e-2)" "unprognostic (6.19e-2)" "unprognostic (9.56e-3)" FFAR2 "FFA2R, GPR43" ENSG00000126262 "Free fatty acid receptor 2" O15552 19 35443907-35451767 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.0;lymphoid tissue: 21.7" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 33.1;Hofbauer cells: 21.7;Intestinal goblet cells: 15.8;Macrophages: 14.7;monocytes: 77.8" "Cancer enhanced" "Detected in many" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "eosinophil: 85.0;neutrophil: 249.8" "Lineage enriched" "Detected in many" 38 "granulocytes: 249.8" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.9;prostate cancer: 2.8" "Breast - Endothelial cells, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Stomach - Neutrophils, Thyroid - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA023985 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 74: Neutrophils - Degranulation" 93 "HPA023985: AB_1849302" "unprognostic (7.75e-3)" "unprognostic (5.65e-2)" "unprognostic (4.33e-3)" "unprognostic (1.68e-1)" "unprognostic (2.18e-1)" "unprognostic (2.55e-2)" "unprognostic (6.16e-2)" "unprognostic (2.04e-1)" "unprognostic (1.92e-2)" "unprognostic (9.04e-2)" "unprognostic (2.30e-2)" "unprognostic (4.60e-2)" "unprognostic (5.17e-4)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (9.42e-2)" "unprognostic (1.03e-2)" FFAR3 "FFA3R, GPR41" ENSG00000185897 "Free fatty acid receptor 3" O14843 19 35358460-35360489 "G-protein coupled receptors, Predicted membrane proteins" "Immunity, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 3.9;lymphoid tissue: 2.4" "Group enriched" "Detected in some" 6 "Gastric mucus-secreting cells: 15.3;granulocytes: 11.2;Macrophages: 7.5;monocytes: 28.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "eosinophil: 2.5;neutrophil: 2.8" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.8" "Not detected" "Not detected" "Breast - Endothelial cells" HPA044681 Uncertain NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 57: Lung - Lung function" "Cluster 11: White matter - Signal transduction" "Cluster 50: Lymphoma - Unknown function" "Cluster 29: Monocytes - Innate immune response" 12 "HPA044681: AB_2679043" "unprognostic (1.15e-1)" "unprognostic (5.16e-3)" "unprognostic (1.45e-1)" "unprognostic (3.08e-2)" "unprognostic (1.03e-3)" "unprognostic (2.21e-2)" "unprognostic (4.46e-2)" "unprognostic (1.34e-1)" "unprognostic (1.92e-4)" "unprognostic (3.80e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-3)" "unprognostic (2.18e-2)" "unprognostic (3.41e-1)" "unprognostic (3.22e-2)" FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adipose tissue: 3.9;intestine: 11.0;lung: 3.4;pituitary gland: 10.7" "Cell type enhanced" "Detected in some" "Early spermatids: 30.4;Intestinal goblet cells: 81.8;Late spermatids: 19.1;Pancreatic endocrine cells: 22.1;Paneth cells: 12.9" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Colon enterocytes, Testis - Late spermatids, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Intestinal goblet cells - Mucin production" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" FPR1 "FMLP, FPR" ENSG00000171051 "Formyl peptide receptor 1" P21462 19 51745172-51804115 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 187.7;lymphoid tissue: 158.7" "Cell type enhanced" "Detected in many" "Hofbauer cells: 206.7;Kupffer cells: 284.1;Macrophages: 169.6;monocytes: 857.7" "Cancer enhanced" "Detected in all" "glioma: 23.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 4198.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 4198.3" "Low cancer specificity" "Detected in some" "Breast - Macrophages, Colon - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophil_2, Prostate - Macrophages, Skeletal muscle - Neutrophils, Skin - Macrophages" "Not detected" "Not detected" "HPA046550, HPA061744" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Neutrophils - Degranulation" 2 "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA046550: AB_2679694, HPA061744: AB_2684600" "unprognostic (5.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (5.48e-3)" "unprognostic (4.59e-2)" "unprognostic (8.34e-2)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.03e-2)" "unprognostic (4.52e-3)" "unprognostic (1.54e-2)" "unprognostic (1.70e-3)" FPR2 "ALX, ALXR, FMLP-R-II, FMLPX, FPR2A, FPRH2, FPRL1, HM63, LXA4R" ENSG00000171049 "Formyl peptide receptor 2" P25090 19 51752026-51770531 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.6" "Cell type enriched" "Detected in some" 18 "monocytes: 793.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "neutrophil: 1191.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 1191.9" "Group enriched" "Detected in some" 4 "Bladder cancer: 2.8;Leukemia: 2.6;liver cancer: 2.1" "Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophil_2, Skeletal muscle - Neutrophils, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Neutrophils" "Not detected" "Not detected" HPA029154 Approved NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 74: Neutrophils - Degranulation" 5 "HPA029154: AB_10602133" "unprognostic (3.11e-1)" "unprognostic (5.20e-2)" "unprognostic (1.71e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (5.04e-2)" "unprognostic (3.90e-4)" "unprognostic (3.41e-5)" "unprognostic (1.08e-2)" "unprognostic (4.69e-2)" "unprognostic (5.10e-2)" "unprognostic (1.90e-1)" FPR3 "FMLPY, FPRH1, FPRL2, RMLP-R-I" ENSG00000187474 "Formyl peptide receptor 3" P25089 19 51795157-51826190 "G-protein coupled receptors, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 63.3;Kupffer cells: 91.7;Langerhans cells: 297.8;Macrophages: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 20 "classical monocyte: 2.3;intermediate monocyte: 6.7;myeloid DC: 2.4" "Group enriched" "Detected in many" 46 "dendritic cells: 2.4;monocytes: 6.7" "Cancer enriched" "Detected in some" 5 "Gastric cancer: 6.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Liver - Plasma proteins" "Cluster 12: Non-specific - Vasculature" "Cluster 32: Non-specific - Cell proliferation" "Cluster 58: Macrophages - Innate immune response" "unprognostic (3.77e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (1.84e-1)" "unprognostic (8.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-2)" "unprognostic (7.14e-2)" "unprognostic (3.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (1.96e-1)" "unprognostic (4.28e-2)" FSHR "FSHRO, LGR1, ODG1" ENSG00000170820 "Follicle stimulating hormone receptor" P23945 2 48962157-49154527 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "ovary: 2.7;testis: 2.2" "Cell type enhanced" "Detected in some" "Early spermatids: 1.8;Excitatory neurons: 9.7;Granulosa cells: 5.2;Late spermatids: 8.1;Oligodendrocyte precursor cells: 2.8;Sertoli cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" 1 "unprognostic (5.94e-2)" "unprognostic (4.06e-3)" "unprognostic (5.78e-2)" FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Peritubular cells: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Fibroblast_1, Skin - Eccrine sweat gland cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 51: Thyroid gland - Unknown function" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Macrophages - Innate immune response" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" FZD10 CD350 ENSG00000111432 "Frizzled class receptor 10" Q9ULW2 12 130162459-130165740 "CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 16.3;skin 1: 9.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 8.1;Basal squamous epithelial cells: 15.1;Lymphatic endothelial cells: 6.4;Smooth muscle cells: 7.5;Squamous epithelial cells: 27.6;Suprabasal keratinocytes: 13.2" "Cancer enhanced" "Detected in many" "endometrial cancer: 13.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 3.3;Esophageal cancer: 3.1" "Adipose subcutaneous - Smooth muscle cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "thalamus: 7.0" "Low region specificity" "Detected in many" "HPA014484, HPA014485" Uncertain Enhanced Nucleoplasm NA NA "Cluster 27: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Squamous epithelial cells - Keratinization" 6 Nucleoplasm "HPA014484: AB_1849132, HPA014485: AB_1849134" "unprognostic (2.41e-3)" "unprognostic (3.29e-1)" "unprognostic (4.74e-2)" "prognostic favorable (5.05e-7)" "unprognostic (2.81e-2)" "unprognostic (4.63e-2)" "unprognostic (8.62e-3)" "unprognostic (6.33e-2)" "unprognostic (5.41e-2)" "unprognostic (3.77e-2)" "unprognostic (2.70e-1)" "unprognostic (2.24e-3)" "unprognostic (2.66e-9)" "unprognostic (2.18e-1)" "unprognostic (3.07e-1)" "unprognostic (1.49e-2)" "unprognostic (1.07e-1)" FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 20.0;Leydig cells: 40.8;Peritubular cells: 35.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 21.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Low cancer specificity" "Detected in all" "Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Ciliated cells - Cilium organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 50: Connective tissue cells - ECM organization" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: AB_2683497" "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" FZD3 ENSG00000104290 "Frizzled class receptor 3" Q9NPG1 8 28494205-28574267 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 14.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 150.7;Rod photoreceptor cells: 91.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 5 "dendritic cells: 9.3;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB024995, HPA042320" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 39: Retina & Testis - Cilium" "Cluster 17: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" Vesicles Nucleoplasm "CAB024995: , HPA042320: AB_2677948" "unprognostic (1.21e-1)" "unprognostic (1.73e-1)" "prognostic favorable (1.17e-4)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (2.57e-4)" "unprognostic (1.69e-2)" "unprognostic (4.26e-4)" "unprognostic (2.11e-1)" "prognostic favorable (3.71e-4)" "unprognostic (2.86e-2)" "unprognostic (1.68e-2)" "unprognostic (1.09e-2)" "unprognostic (1.38e-1)" "unprognostic (4.44e-2)" "unprognostic (3.77e-2)" "unprognostic (6.09e-3)" FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 115.9" "Cell type enhanced" "Detected in many" "Adipocytes: 82.2;Basal prostatic cells: 29.7;Collecting duct cells: 27.2;Endothelial cells: 61.4;Fibroblasts: 32.6;Skeletal myocytes: 28.3;Smooth muscle cells: 27.3" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 4 "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" FZD5 "C2orf31, DKFZP434E2135, HFZ5" ENSG00000163251 "Frizzled class receptor 5" Q13467 2 207762598-207769906 "G-protein coupled receptors, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 22.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.8;Alveolar cells type 2: 61.9;Distal enterocytes: 99.0;Hepatocytes: 48.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA052361 Approved NA NA "Cluster 37: Liver & Intestine - Lipid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Intestinal goblet cells - Mucin production" 2 "HPA052361: AB_2681799" "unprognostic (4.97e-2)" "unprognostic (6.94e-2)" "unprognostic (2.20e-1)" "unprognostic (2.56e-1)" "unprognostic (1.53e-1)" "unprognostic (2.82e-1)" "unprognostic (4.80e-3)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (1.48e-3)" "unprognostic (1.29e-1)" "unprognostic (8.00e-2)" "unprognostic (7.72e-2)" "unprognostic (2.51e-1)" "unprognostic (9.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.15e-3)" FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 95.4;Glandular and luminal cells: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" FZD7 FzE3 ENSG00000155760 "Frizzled class receptor 7" O75084 2 202033855-202038441 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast glandular cells: 28.0;Breast myoepithelial cells: 29.1;Cardiomyocytes: 23.4;Mucus glandular cells: 28.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 60.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059979, HPA069165, HPA076183" Approved Supported Vesicles NA NA "Cluster 66: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Fibroblasts - ECM organization" 18 Vesicles "HPA059979: , HPA069165: AB_2686096, HPA076183: " "unprognostic (3.44e-2)" "unprognostic (6.89e-2)" "unprognostic (9.30e-3)" "unprognostic (2.44e-3)" "unprognostic (4.92e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.71e-5)" "unprognostic (1.40e-1)" "unprognostic (4.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.87e-3)" "unprognostic (8.16e-3)" "unprognostic (1.43e-1)" "unprognostic (4.16e-2)" "unprognostic (2.05e-3)" FZD8 ENSG00000177283 "Frizzled class receptor 8" Q9H461 10 35638247-35642296 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.9;Muller glia cells: 24.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 85.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA045025, HPA071142" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Alveolar cells - Lung function" 1 "Endoplasmic reticulum" "HPA045025: AB_10795888, HPA071142: AB_2686349" "unprognostic (1.20e-1)" "unprognostic (4.42e-3)" "unprognostic (1.85e-2)" "unprognostic (1.97e-1)" "unprognostic (2.21e-2)" "unprognostic (2.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.08e-3)" "unprognostic (1.11e-1)" "unprognostic (1.53e-1)" "prognostic favorable (8.21e-4)" "unprognostic (4.92e-2)" "unprognostic (2.25e-1)" "unprognostic (4.85e-2)" "unprognostic (1.68e-1)" "unprognostic (7.34e-3)" "unprognostic (1.19e-1)" FZD9 "CD349, FZD3" ENSG00000188763 "Frizzled class receptor 9" O00144 7 73433778-73436120 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.2;skeletal muscle: 6.8;testis: 4.5" "Cell type enhanced" "Detected in some" "Early spermatids: 4.2;Late spermatids: 13.7;Muller glia cells: 5.4;Oligodendrocyte precursor cells: 14.1" "Cancer enriched" "Detected in many" 5 "melanoma: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Late spermatids - Unknown function" "unprognostic (9.60e-2)" "unprognostic (4.03e-2)" "unprognostic (3.16e-2)" "unprognostic (9.15e-3)" "unprognostic (1.10e-1)" "unprognostic (6.91e-2)" "unprognostic (2.29e-2)" "unprognostic (2.26e-1)" "unprognostic (2.04e-1)" "unprognostic (7.17e-3)" "unprognostic (1.20e-1)" "unprognostic (7.24e-2)" "unprognostic (5.90e-5)" "unprognostic (8.99e-2)" "unprognostic (4.57e-2)" "unprognostic (1.22e-1)" "unprognostic (5.21e-2)" GABBR1 "GPRC3A, hGB1a" ENSG00000204681 "Gamma-aminobutyric acid type B receptor subunit 1" Q9UBS5 6 29555629-29633976 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 228.8" "Cell type enhanced" "Detected in many" "Astrocytes: 142.7;Excitatory neurons: 56.7;Horizontal cells: 56.0;Inhibitory neurons: 65.2;Oligodendrocyte precursor cells: 67.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050483, HPA058459" Uncertain Approved Centrosome "Intracellular and membrane" Receptor NA NA "Cluster 64: Neuronal - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Astrocytes - Unknown function" 4 Centrosome "HPA050483: AB_2681140, HPA058459: " "unprognostic (1.01e-1)" "unprognostic (2.07e-3)" "unprognostic (3.22e-3)" "unprognostic (2.93e-3)" "unprognostic (3.37e-1)" "unprognostic (2.65e-1)" "unprognostic (7.95e-4)" "unprognostic (5.44e-2)" "unprognostic (4.24e-2)" "unprognostic (1.14e-1)" "prognostic favorable (2.54e-5)" "unprognostic (1.23e-3)" "prognostic unfavorable (3.77e-10)" "unprognostic (3.82e-2)" "unprognostic (2.26e-1)" "unprognostic (3.87e-2)" "unprognostic (2.55e-2)" GABBR2 "GABABR2, GPR51, GPRC3B, HG20" ENSG00000136928 "Gamma-aminobutyric acid type B receptor subunit 2" O75899 9 98288109-98708935 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 62.9" "Group enriched" "Detected in some" 5 "Excitatory neurons: 373.5;Inhibitory neurons: 377.6" "Group enriched" "Detected in many" 10 "glioma: 7.2;thyroid cancer: 11.6;urothelial cancer: 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 8.9" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013820, HPA031684, CAB079065" Enhanced Approved NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 65: Neurons - Synaptic function" 2 "CAB079065: , HPA013820: AB_1849364, HPA031684: AB_2673993" "unprognostic (2.00e-1)" "unprognostic (7.56e-2)" "unprognostic (3.75e-1)" "unprognostic (3.09e-5)" "unprognostic (2.52e-1)" "unprognostic (1.16e-1)" "unprognostic (2.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.66e-1)" "unprognostic (4.43e-2)" "unprognostic (1.43e-2)" "unprognostic (2.06e-1)" "unprognostic (1.76e-2)" "unprognostic (3.52e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-2)" "unprognostic (3.45e-2)" GALR1 "GALNR, GALNR1" ENSG00000166573 "Galanin receptor 1" P47211 18 77249848-77277900 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;pituitary gland: 1.4" "Group enriched" "Detected in some" 4 "Early spermatids: 76.2;Oligodendrocyte precursor cells: 40.1" "Cancer enriched" "Detected in single" 6 "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 1.4" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in some" "hypothalamus: 5.2" "Low region specificity" "Detected in all" HPA074584 Supported "Plasma membrane" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 66: Non-specific - Mitochondria" "Cluster 18: Early spermatids - Unknown function" "Plasma membrane" "HPA074584: " "unprognostic (1.65e-1)" "unprognostic (1.56e-2)" "unprognostic (2.85e-1)" "unprognostic (3.00e-1)" "unprognostic (2.11e-1)" "unprognostic (2.77e-3)" "unprognostic (1.31e-2)" "unprognostic (5.34e-3)" "unprognostic (7.33e-3)" "unprognostic (9.49e-2)" "unprognostic (2.18e-1)" GALR2 GALNR2 ENSG00000182687 "Galanin receptor 2" O43603 17 76074781-76077537 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 7.4" "Cell type enhanced" "Detected in some" "dendritic cells: 6.1;granulocytes: 3.7;Macrophages: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 3.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA044513 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Dendritic cells - Antigen presentation" "HPA044513: AB_10962510" "unprognostic (1.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.16e-1)" "unprognostic (1.37e-2)" "unprognostic (2.62e-2)" "unprognostic (3.54e-1)" "unprognostic (3.49e-2)" "unprognostic (3.43e-1)" "unprognostic (7.62e-2)" "unprognostic (1.39e-1)" "unprognostic (9.32e-5)" "unprognostic (2.31e-1)" "unprognostic (2.11e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-1)" "unprognostic (4.04e-2)" "unprognostic (8.14e-2)" GALR3 ENSG00000128310 "Galanin receptor 3" O60755 22 37823382-37825485 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Glandular and luminal cells: 1.3;Late spermatids: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 70: DU4475 - Unknown function" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "unprognostic (4.45e-2)" "unprognostic (1.45e-2)" "unprognostic (4.60e-3)" "unprognostic (7.07e-2)" "unprognostic (7.63e-2)" "unprognostic (8.17e-2)" "unprognostic (4.18e-2)" "unprognostic (2.16e-2)" "unprognostic (3.74e-2)" "unprognostic (1.49e-1)" "unprognostic (2.07e-1)" "unprognostic (1.66e-2)" "unprognostic (7.37e-2)" "unprognostic (8.35e-2)" "unprognostic (4.45e-2)" GCGR GGR ENSG00000215644 "Glucagon receptor" P47871 17 81804132-81814008 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "kidney: 48.6;liver: 165.5" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 56.2" "Cancer enriched" "Detected in many" 4 "liver cancer: 10.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071228 Uncertain "Golgi apparatus" NA NA "Cluster 1: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 62: Hepatocytes - Metabolism" "Golgi apparatus" "HPA071228: AB_2686368" "unprognostic (3.28e-4)" "unprognostic (9.30e-2)" "unprognostic (2.20e-1)" "unprognostic (1.53e-4)" "unprognostic (1.11e-1)" "unprognostic (2.30e-3)" "unprognostic (4.38e-2)" "unprognostic (1.79e-3)" "unprognostic (2.18e-1)" "unprognostic (2.77e-1)" "unprognostic (3.09e-1)" "unprognostic (2.61e-1)" "unprognostic (6.42e-2)" "unprognostic (5.99e-3)" "unprognostic (1.71e-1)" "unprognostic (1.17e-3)" "unprognostic (8.36e-3)" GHRHR ENSG00000106128 "Growth hormone releasing hormone receptor" Q02643 7 30938669-30993254 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 351 "pituitary gland: 206.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Spermatocytes: 1.6;Spermatogonia: 2.6" "Cancer enhanced" "Detected in single" "liver cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "prostate cancer: 2.1" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Intracellular and membrane" Receptor NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 67: Spermatogonia - Spermatogenesis" "unprognostic (8.32e-2)" "unprognostic (1.45e-1)" "unprognostic (9.30e-2)" "unprognostic (1.39e-1)" "unprognostic (7.23e-2)" "unprognostic (4.15e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (1.43e-2)" "unprognostic (1.47e-1)" "unprognostic (5.87e-3)" GHSR ENSG00000121853 "Growth hormone secretagogue receptor" Q92847 3 172443291-172448456 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "pituitary gland: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 4 "hypothalamus: 32.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 3.3" "Low region specificity" "Detected in all" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 77: Plasma cells - Protein processing" "unprognostic (1.27e-1)" "unprognostic (3.31e-2)" GIPR ENSG00000010310 "Gastric inhibitory polypeptide receptor" P48546 19 45668221-45683722 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 22.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 30.8;Enteroendocrine cells: 17.7;Gastric mucus-secreting cells: 34.2;Rod photoreceptor cells: 18.5" "Cancer enriched" "Detected in many" 5 "pancreatic cancer: 4.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB022710, HPA068054" Uncertain Uncertain Vesicles NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 Vesicles "CAB022710: , HPA068054: " "unprognostic (2.40e-2)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.31e-2)" "unprognostic (2.65e-1)" "unprognostic (3.70e-4)" "unprognostic (1.82e-2)" "unprognostic (2.94e-2)" "unprognostic (1.42e-1)" "unprognostic (1.72e-2)" "unprognostic (4.85e-3)" "unprognostic (2.78e-1)" "unprognostic (1.72e-2)" "unprognostic (1.19e-1)" "unprognostic (1.37e-1)" "unprognostic (3.37e-2)" "unprognostic (2.59e-2)" GLP1R GLP-1R ENSG00000112164 "Glucagon like peptide 1 receptor" P43220 6 39048781-39091303 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2.6;pancreas: 6.8;salivary gland: 2.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 1.0;Cardiomyocytes: 5.2;Exocrine glandular cells: 1.7;Inhibitory neurons: 1.2;Melanocytes: 1.7;Pancreatic endocrine cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.9" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells" "Region enriched" "Detected in many" 4 "basal ganglia: 20.7" "Low region specificity" "Detected in some" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 68: Cardiomyocytes - Muscle contraction" 10 "unprognostic (4.06e-3)" "unprognostic (5.38e-6)" "unprognostic (1.80e-2)" "unprognostic (4.16e-2)" "unprognostic (4.98e-2)" "unprognostic (3.55e-1)" "unprognostic (2.11e-1)" "unprognostic (1.38e-1)" "unprognostic (9.76e-2)" "unprognostic (3.29e-1)" "unprognostic (1.73e-1)" "unprognostic (8.60e-3)" "unprognostic (2.47e-1)" "unprognostic (1.15e-2)" "unprognostic (1.42e-2)" GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 11.8;intestine: 13.0;urinary bladder: 11.4" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 26.6" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 17.9;liver cancer: 9.1;Rhabdoid: 8.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Liver - Hepatic stellate cells, Lung - Fibroblast_2, Pancreas - Fibroblasts" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 66: Photoreceptor cells - Visual perception" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" GNRHR "GRHR, LHRHR" ENSG00000109163 "Gonadotropin releasing hormone receptor" P30968 4 67737118-67754388 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "pituitary gland: 5.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.1;Granulosa cells: 6.3;Inhibitory neurons: 1.2;Suprabasal keratinocytes: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA013424 Enhanced NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 24: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Suprabasal keratinocytes - Cornification" "HPA013424: AB_2668840" "unprognostic (2.77e-1)" "unprognostic (1.58e-1)" "unprognostic (4.05e-1)" "unprognostic (1.78e-1)" "unprognostic (4.65e-1)" "unprognostic (8.75e-3)" "unprognostic (3.09e-2)" "unprognostic (1.34e-1)" "unprognostic (1.90e-1)" "unprognostic (1.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.63e-1)" "unprognostic (9.03e-2)" "unprognostic (3.23e-2)" "unprognostic (9.67e-2)" "unprognostic (1.22e-3)" "unprognostic (3.99e-2)" GPBAR1 "BG37, GPCR, GPCR19, GPR131, M-BAR, MGC40597, TGR5" ENSG00000179921 "G protein-coupled bile acid receptor 1" Q8TDU6 2 218259496-218263861 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.9;breast: 17.3;gallbladder: 16.7" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 21.4;Enteroendocrine cells: 28.5;Hofbauer cells: 34.1;Kupffer cells: 34.5;Macrophages: 16.6;monocytes: 40.1" "Cancer enhanced" "Detected in many" "pancreatic cancer: 3.5" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 4 "classical monocyte: 288.5;intermediate monocyte: 712.6;non-classical monocyte: 698.6" "Lineage enriched" "Detected in many" 5 "monocytes: 712.6" "Group enriched" "Detected in some" 5 "lymphoma: 2.0;Neuroblastoma: 2.2;Rhabdoid: 5.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA062890 Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 29: Monocytes - Innate immune response" "HPA062890: AB_2684896" "unprognostic (8.47e-2)" "unprognostic (3.72e-3)" "unprognostic (1.88e-2)" "unprognostic (9.49e-2)" "unprognostic (1.44e-2)" "unprognostic (4.66e-2)" "unprognostic (2.54e-1)" "unprognostic (2.63e-1)" "unprognostic (8.76e-3)" "unprognostic (4.32e-2)" "unprognostic (4.64e-2)" "unprognostic (1.55e-1)" "unprognostic (7.40e-7)" "unprognostic (4.18e-2)" "unprognostic (4.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" GPER1 "CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR" ENSG00000164850 "G protein-coupled estrogen receptor 1" Q99527 7 1082208-1093815 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Apoptosis, Cell cycle, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 38.4" "Cell type enhanced" "Detected in many" "Adipocytes: 8.5;Distal enterocytes: 10.3;Hepatocytes: 22.9;Kupffer cells: 17.8;Muller glia cells: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.9;intermediate monocyte: 2.7;myeloid DC: 5.8" "Group enriched" "Detected in many" 23 "dendritic cells: 5.8;monocytes: 2.9" "Cancer enhanced" "Detected in many" "lymphoma: 11.1" "Liver - Hepatocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016718, HPA027052" Approved Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 43: Non-specific - Mitochondrial translation" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" Nucleoli "Nucleoplasm, Vesicles, Cytosol" "HPA016718: , HPA027052: AB_10612112" "unprognostic (4.74e-2)" "unprognostic (1.32e-1)" "unprognostic (3.09e-2)" "prognostic favorable (1.17e-4)" "unprognostic (2.17e-1)" "unprognostic (6.17e-2)" "unprognostic (3.45e-1)" "unprognostic (6.38e-2)" "unprognostic (2.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (2.49e-1)" "unprognostic (2.37e-2)" "unprognostic (1.79e-2)" "unprognostic (1.58e-1)" "unprognostic (7.26e-2)" "unprognostic (7.78e-2)" GPR101 ENSG00000165370 "G protein-coupled receptor 101" Q96P66 X 137023929-137033995 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "brain: 5.1" "Cell type enriched" "Detected in single" 4 "Plasma cells: 2.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "basal ganglia: 26.4;hypothalamus: 30.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 38.3" "Low region specificity" "Detected in many" HPA001084 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 77: Plasma cells - Protein processing" 16 "HPA001084: AB_1078920" GPR119 "GPCR2, hGPCR2" ENSG00000147262 "G protein-coupled receptor 119" Q8TDV5 X 130379449-130385674 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "pancreas: 1.9" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "pancreatic cancer: 2.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 1.8" "Pancreas - Alpha cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "prognostic favorable (6.93e-4)" GPR12 "GPCR21, PPP1R84" ENSG00000132975 "G protein-coupled receptor 12" P47775 13 26755200-26760786 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.1;retina: 8.1;skin 1: 5.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.2;Hofbauer cells: 14.7;Horizontal cells: 22.7;Inhibitory neurons: 15.1;Salivary duct cells: 8.3;Secretory cells: 6.6" "Group enriched" "Detected in some" 7 "breast cancer: 0.5;glioma: 0.8;ovarian cancer: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.2;Rhabdoid: 2.4" "Breast - Breast glandular cells (progenitors), Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050972 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA050972: AB_2681295" "unprognostic (2.37e-2)" "unprognostic (9.64e-3)" "unprognostic (3.75e-1)" "unprognostic (3.30e-1)" "unprognostic (1.40e-2)" "unprognostic (4.65e-2)" "unprognostic (1.42e-1)" "unprognostic (7.35e-2)" "unprognostic (5.53e-2)" "unprognostic (3.83e-2)" "unprognostic (2.40e-1)" GPR132 G2A ENSG00000183484 "G protein-coupled receptor 132" Q9UNW8 14 105049395-105065445 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Stress response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;lymphoid tissue: 7.6" "Cell type enhanced" "Detected in some" "B-cells: 18.7;Langerhans cells: 60.0;Macrophages: 36.3;monocytes: 119.0;NK-cells: 18.7;T-cells: 22.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 13.7;Myeloma: 7.9" "Adipose visceral - Macrophages, Prostate - T-cells, Skeletal muscle - Macrophages" "HPA029694, HPA029695" Supported NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Monocytes - Innate immune response" "HPA029694: AB_10600213, HPA029695: AB_10601984" "unprognostic (2.71e-3)" "prognostic favorable (3.21e-4)" "unprognostic (1.68e-2)" "unprognostic (1.07e-3)" "unprognostic (1.16e-1)" "prognostic favorable (6.44e-4)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (3.35e-2)" "unprognostic (8.54e-2)" "unprognostic (1.10e-1)" "unprognostic (4.18e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (6.71e-2)" "unprognostic (4.60e-2)" "unprognostic (1.23e-3)" "unprognostic (2.72e-1)" GPR135 "HUMNPIIY20, PAFR" ENSG00000181619 "G protein-coupled receptor 135" Q8IZ08 14 59429022-59465380 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 8 "Early spermatids: 143.5;Late spermatids: 221.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA045337 Uncertain NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 63: Late spermatids - Spermatogenesis" "HPA045337: AB_10960528" "unprognostic (1.55e-1)" "unprognostic (3.00e-1)" "unprognostic (6.09e-3)" "unprognostic (1.14e-1)" "unprognostic (4.20e-2)" "unprognostic (8.47e-2)" "unprognostic (3.22e-1)" "unprognostic (3.91e-2)" "unprognostic (4.64e-2)" "unprognostic (1.09e-1)" "unprognostic (2.47e-2)" "unprognostic (1.55e-1)" "unprognostic (2.75e-5)" "unprognostic (1.33e-2)" "unprognostic (1.90e-1)" "unprognostic (2.71e-2)" "unprognostic (2.68e-3)" GPR139 PGR3 ENSG00000180269 "G protein-coupled receptor 139" Q6DWJ6 16 20028239-20073890 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA046596 Uncertain NA NA "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" "HPA046596: AB_2679713" "unprognostic (2.94e-1)" GPR141 PGR13 ENSG00000187037 "G protein-coupled receptor 141" Q7Z602 7 37683766-37833788 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 25.6" "Cell type enhanced" "Detected in some" "granulocytes: 14.4;Langerhans cells: 8.9;Macrophages: 5.2;NK-cells: 13.7;Oligodendrocytes: 13.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 11.1;eosinophil: 8.0;gdT-cell: 4.4;memory CD8 T-cell: 4.3;myeloid DC: 5.9;naive CD8 T-cell: 2.9;neutrophil: 10.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 4.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 49: HMC-1 - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" 8 "unprognostic (4.91e-2)" "unprognostic (3.44e-1)" "unprognostic (3.26e-4)" "unprognostic (4.70e-3)" "unprognostic (8.67e-2)" "unprognostic (2.00e-2)" "unprognostic (3.01e-1)" "unprognostic (2.51e-2)" "unprognostic (7.93e-3)" "unprognostic (1.44e-1)" "unprognostic (1.51e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-3)" "unprognostic (1.39e-2)" "unprognostic (4.14e-2)" "unprognostic (1.79e-1)" "unprognostic (1.60e-1)" GPR142 PGR2 ENSG00000257008 "G protein-coupled receptor 142" Q7Z601 17 74367458-74372600 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "stomach 1: 1.7" "Cell type enriched" "Detected in single" 6 "Enteroendocrine cells: 1.1" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA031392 Uncertain Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "Plasma membrane, Cytosol" "Cell Junctions" "HPA031392: AB_10601935" "unprognostic (6.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (4.16e-2)" "unprognostic (4.85e-7)" "unprognostic (3.95e-2)" "unprognostic (7.72e-4)" "unprognostic (1.93e-1)" "unprognostic (1.68e-3)" GPR143 OA1 ENSG00000101850 "G protein-coupled receptor 143" P51810 X 9725346-9786297 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 24.0" "Cell type enriched" "Detected in many" 4 "Melanocytes: 190.7" "Cancer enriched" "Detected in all" 9 "melanoma: 84.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.1" "Lineage enriched" "Detected in single" 19 "granulocytes: 3.1" "Cancer enriched" "Detected in many" 5 "skin cancer: 74.2" "Adipose visceral - Mesothelial cells, Skin - Melanocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA003648 Enhanced NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 24: Cytotrophoblasts - Mitochondria" 2 "HPA003648: AB_2667028" "unprognostic (4.60e-2)" "prognostic favorable (8.73e-4)" "unprognostic (7.43e-3)" "unprognostic (5.41e-2)" "unprognostic (4.62e-3)" "unprognostic (2.00e-2)" "unprognostic (3.05e-1)" "unprognostic (2.64e-3)" "unprognostic (3.78e-1)" "unprognostic (5.89e-2)" "unprognostic (8.18e-2)" "unprognostic (8.40e-2)" "prognostic favorable (2.45e-5)" "unprognostic (2.75e-1)" "unprognostic (2.07e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" GPR146 PGR8 ENSG00000164849 "G protein-coupled receptor 146" Q96CH1 7 1044546-1059261 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "adipose tissue: 46.4" "Cell type enhanced" "Detected in many" "Adipocytes: 96.3;Endothelial cells: 55.1;Extravillous trophoblasts: 292.4;Lymphatic endothelial cells: 51.2;Syncytiotrophoblasts: 89.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 95.4;naive CD4 T-cell: 25.6" "Group enriched" "Detected in many" 4 "granulocytes: 95.4;T-cells: 25.6" "Low cancer specificity" "Detected in many" "Prostate - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 4: Extravillous trophoblasts - Unknown function" "unprognostic (3.39e-2)" "unprognostic (7.83e-2)" "unprognostic (6.27e-4)" "unprognostic (5.51e-3)" "unprognostic (1.78e-1)" "unprognostic (2.33e-1)" "unprognostic (2.30e-1)" "unprognostic (2.69e-1)" "unprognostic (2.99e-2)" "unprognostic (3.48e-3)" "unprognostic (2.51e-2)" "unprognostic (1.70e-1)" "unprognostic (1.14e-1)" "unprognostic (3.27e-3)" "unprognostic (1.41e-1)" "unprognostic (4.19e-2)" "unprognostic (1.03e-2)" GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pancreas - Alpha cells, Pancreas - Beta cells" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Plasma membrane" "HPA046655: , HPA060527: AB_2684307" "unprognostic (7.16e-4)" "unprognostic (3.38e-1)" GPR149 "IEDA, PGR10, R35" ENSG00000174948 "G protein-coupled receptor 149" Q86SP6 3 154334943-154430190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;seminal vesicle: 1.4" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 46.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "prostate cancer: 1.0" "Region enhanced" "Detected in many" "basal ganglia: 15.0" "Low region specificity" "Detected in many" HPA018020 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA018020: AB_1849334" GPR15 ENSG00000154165 "G protein-coupled receptor 15" P49685 3 98531978-98534681 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 30.3" "Group enriched" "Detected in some" 13 "B-cells: 8.7;Plasma cells: 33.8;T-cells: 22.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6 "memory B-cell: 3.6;memory CD4 T-cell: 10.8;memory CD8 T-cell: 5.1;T-reg: 12.2" "Group enriched" "Detected in many" 26 "B-cells: 3.6;T-cells: 12.2" "Cancer enhanced" "Detected in many" "lymphoma: 31.6" "Adipose visceral - T-cells, Breast - Plasma cells, Thyroid - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA013775 Approved NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 45: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 77: Plasma cells - Protein processing" "HPA013775: AB_1849264" "unprognostic (8.03e-2)" "unprognostic (1.04e-2)" "unprognostic (3.72e-3)" "unprognostic (5.66e-2)" "unprognostic (9.48e-3)" "unprognostic (5.60e-5)" "unprognostic (5.17e-1)" "unprognostic (6.77e-3)" "unprognostic (3.96e-1)" "unprognostic (3.03e-2)" "unprognostic (2.82e-1)" "unprognostic (2.83e-1)" "unprognostic (4.04e-3)" "unprognostic (4.23e-3)" "unprognostic (1.89e-1)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" GPR150 PGR11 ENSG00000178015 "G protein-coupled receptor 150" Q8NGU9 5 95620087-95622142 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.5;pancreas: 6.7" "Cell type enhanced" "Detected in some" "Early spermatids: 5.4;Extravillous trophoblasts: 5.9;Hofbauer cells: 2.9;Oocytes: 2.9;Sertoli cells: 2.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Macrophages, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in some" HPA026635 Uncertain NA NA "Cluster 32: Endocrine & Neural - Unknown function" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Pancreatic exocrine cells - Proteolysis" "HPA026635: AB_1849266" "unprognostic (3.03e-2)" "unprognostic (6.88e-3)" "unprognostic (1.01e-1)" "unprognostic (1.01e-2)" "unprognostic (5.95e-2)" "unprognostic (5.34e-4)" "unprognostic (1.98e-2)" "unprognostic (6.36e-2)" "unprognostic (3.13e-1)" "unprognostic (1.17e-2)" "unprognostic (1.94e-3)" "unprognostic (1.88e-2)" "unprognostic (1.76e-1)" "unprognostic (3.23e-2)" "unprognostic (4.42e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" GPR151 "GALR4, PGR7" ENSG00000173250 "G protein-coupled receptor 151" Q8TDV0 5 146513144-146516190 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4 "Cone photoreceptor cells: 3.4" "Not detected" "Not detected" "Region enriched" "Detected in single" 22 "midbrain: 17.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 19 "thalamus: 30.6" "Region enriched" "Detected in single" 9 "thalamus: 6.1" HPA065728 Supported NA NA "Cluster 46: Brainstem - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 66: Photoreceptor cells - Visual perception" 35 "HPA065728: " "unprognostic (2.09e-1)" "unprognostic (2.30e-1)" "unprognostic (1.14e-1)" "unprognostic (1.32e-2)" GPR152 PGR5 ENSG00000175514 "G protein-coupled receptor 152" Q8TDT2 11 67451301-67452729 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035078 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" 163 "HPA035078: AB_10670286" "unprognostic (3.81e-2)" "unprognostic (1.69e-1)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (3.76e-3)" GPR153 PGR1 ENSG00000158292 "G protein-coupled receptor 153" Q6NV75 1 6247353-6261098 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.3;Horizontal cells: 46.6;Intestinal goblet cells: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 36.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007159 Approved NA NA "Cluster 13: Skin - Cornification" "Cluster 38: Sub-cortical - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA007159: AB_1849268" "unprognostic (1.02e-2)" "unprognostic (2.40e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (3.07e-4)" "unprognostic (5.74e-3)" "unprognostic (3.33e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (3.75e-4)" "unprognostic (8.54e-2)" "unprognostic (1.02e-2)" "unprognostic (1.31e-1)" "unprognostic (1.51e-2)" "unprognostic (1.53e-3)" "unprognostic (2.00e-1)" "unprognostic (2.93e-1)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" GPR156 "GABABL, PGR28" ENSG00000175697 "G protein-coupled receptor 156" Q8NFN8 3 120164645-120285222 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.6" "Group enriched" "Detected in some" 4 "Astrocytes: 14.2;Early spermatids: 8.1;Late spermatids: 19.6;Oligodendrocyte precursor cells: 12.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA028642, HPA028644" Uncertain Supported "Plasma membrane" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 39: Astrocytes - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 36: Late spermatids - Unknown function" "Plasma membrane" "HPA028642: AB_10599711, HPA028644: AB_10600441" "unprognostic (2.85e-3)" "unprognostic (1.02e-1)" "unprognostic (3.53e-3)" "unprognostic (2.02e-3)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.62e-4)" "unprognostic (2.03e-1)" "unprognostic (4.54e-4)" "unprognostic (5.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (4.03e-5)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (4.91e-3)" "unprognostic (6.71e-2)" GPR157 FLJ12132 ENSG00000180758 "G protein-coupled receptor 157" Q5UAW9 1 9100305-9129102 "G-protein coupled receptors, Predicted membrane proteins" Differentiation "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 57.4" "Group enriched" "Detected in many" 4 "Langerhans cells: 315.3;Schwann cells: 117.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 23.9" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028697, HPA054948" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Dendritic cells - Antigen presentation" Cytosol "Plasma membrane" "HPA028697: AB_10601810, HPA054948: " "unprognostic (2.83e-3)" "unprognostic (1.13e-2)" "unprognostic (5.91e-2)" "unprognostic (5.42e-2)" "unprognostic (2.13e-4)" "unprognostic (7.11e-2)" "unprognostic (7.52e-3)" "unprognostic (3.60e-2)" "unprognostic (9.20e-2)" "unprognostic (1.26e-1)" "unprognostic (9.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.02e-2)" "unprognostic (1.70e-2)" "unprognostic (1.21e-1)" "unprognostic (4.30e-2)" "unprognostic (3.04e-3)" GPR158 KIAA1136 ENSG00000151025 "G protein-coupled receptor 158" Q5T848 10 25174802-25602229 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.5;retina: 4.3" "Cell type enhanced" "Detected in some" "Excitatory neurons: 354.8;Horizontal cells: 65.5;Inhibitory neurons: 288.6;Oligodendrocyte precursor cells: 393.8;Oligodendrocytes: 94.6" "Cancer enhanced" "Detected in many" "glioma: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 10.9" "Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013185 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 65: Neurons - Synaptic function" "HPA013185: AB_2113957" "unprognostic (4.43e-2)" "unprognostic (3.14e-2)" "unprognostic (7.42e-2)" "unprognostic (2.66e-5)" "unprognostic (5.67e-2)" "unprognostic (9.37e-2)" "unprognostic (4.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.22e-1)" "unprognostic (4.37e-2)" "unprognostic (8.09e-3)" "unprognostic (1.72e-1)" "unprognostic (2.60e-6)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (1.21e-3)" "unprognostic (3.90e-1)" GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8;parathyroid gland: 209.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 183.5;Paneth cells: 131.8;Proximal enterocytes: 348.1;Proximal tubular cells: 138.5;Undifferentiated cells: 183.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Vascular Endothelial cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 22: Proximal enterocytes - Digestion" 2 "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" GPR161 RE2 ENSG00000143147 "G protein-coupled receptor 161" Q8N6U8 1 168079542-168137667 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 40.1;smooth muscle: 26.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 18.3;Horizontal cells: 44.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA015576, HPA072047" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 62: Connective tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 9: Endometrial stromal cells - Transcription" 4 Nucleoplasm Nucleoli "HPA015576: AB_1849283, HPA072047: AB_2686484" "unprognostic (1.45e-1)" "unprognostic (3.78e-2)" "unprognostic (2.68e-2)" "unprognostic (1.58e-3)" "unprognostic (1.87e-1)" "unprognostic (6.84e-2)" "unprognostic (3.24e-3)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.04e-2)" "unprognostic (5.45e-2)" "unprognostic (1.31e-2)" "unprognostic (5.57e-6)" "unprognostic (3.93e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-2)" "unprognostic (6.34e-2)" GPR162 "A-2, GRCA" ENSG00000250510 "G protein-coupled receptor 162" Q16538 12 6821624-6829972 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 147.1;choroid plexus: 75.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 70.3;Ciliated cells: 50.4;Excitatory neurons: 35.5;Horizontal cells: 71.8;Inhibitory neurons: 31.5;Muller glia cells: 46.1" "Cancer enriched" "Detected in many" 6 "glioma: 16.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 17.5" "Group enriched" "Detected in many" 6 "granulocytes: 17.5;monocytes: 6.9" "Cancer enhanced" "Detected in many" "Rhabdoid: 18.0" "Heart muscle - Fibroblasts, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055135 Enhanced Approved "Centriolar satellite" "Intracellular and membrane" Receptor NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 42: Ciliated cells - Cilium assembly" 2 "Centriolar satellite" "HPA055135: AB_2682710" "unprognostic (4.76e-2)" "unprognostic (8.00e-2)" "unprognostic (8.24e-3)" "unprognostic (1.31e-2)" "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.78e-2)" "unprognostic (2.25e-2)" "unprognostic (5.83e-3)" "unprognostic (1.18e-1)" "prognostic favorable (4.29e-5)" "unprognostic (3.82e-3)" "prognostic unfavorable (1.37e-6)" "unprognostic (3.10e-3)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (3.64e-2)" GPR17 ENSG00000144230 "G protein-coupled receptor 17" Q13304 2 127645864-127652639 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.6;intestine: 23.0" "Cell type enriched" "Detected in some" 10 "Oligodendrocyte precursor cells: 54.7" "Cancer enriched" "Detected in some" 32 "glioma: 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "naive B-cell: 1.9" "Lineage enriched" "Detected in single" 19 "B-cells: 1.9" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029766 Enhanced Supported Approved Vesicles NA NA "Cluster 64: Neuronal - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 76: Oligodendrocyte precursor - Unknown function" Vesicles "HPA029766: AB_10612114" "unprognostic (8.10e-2)" "unprognostic (1.73e-1)" "unprognostic (2.61e-1)" "unprognostic (1.42e-2)" "unprognostic (1.54e-1)" "unprognostic (5.19e-2)" "unprognostic (2.77e-5)" "unprognostic (8.40e-3)" "unprognostic (2.92e-1)" "unprognostic (3.25e-2)" "unprognostic (1.61e-3)" "unprognostic (6.60e-2)" "unprognostic (2.11e-3)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" GPR171 H963 ENSG00000174946 "G protein-coupled receptor 171" O14626 3 151197832-151203216 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.5;lymphoid tissue: 20.7" "Cell type enriched" "Detected in some" 4 "T-cells: 125.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 110.6" "Lineage enriched" "Detected in many" 15 "T-cells: 110.6" "Group enriched" "Detected in some" 39 "Leukemia: 2.3;lymphoma: 6.0;Myeloma: 4.1" "Kidney - T-cells, Liver - T-cells, Prostate - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA067323 Supported NA NA "Cluster 27: T-cells - Unknown function" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA067323: " "unprognostic (6.82e-6)" "unprognostic (4.90e-3)" "unprognostic (7.10e-2)" "unprognostic (6.85e-4)" "unprognostic (2.80e-3)" "unprognostic (1.04e-3)" "unprognostic (4.19e-4)" "unprognostic (6.09e-2)" "unprognostic (4.93e-3)" "unprognostic (1.01e-3)" "unprognostic (8.84e-2)" "unprognostic (1.08e-1)" "unprognostic (4.72e-6)" "unprognostic (1.31e-1)" "unprognostic (4.17e-2)" "unprognostic (4.58e-2)" "unprognostic (1.02e-2)" GPR173 SREB3 ENSG00000184194 "G protein-coupled receptor 173" Q9NS66 X 53048789-53080615 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.2;pituitary gland: 17.9" "Cell type enhanced" "Detected in some" "Astrocytes: 41.2;Excitatory neurons: 19.0;Inhibitory neurons: 13.5;Oligodendrocyte precursor cells: 46.2;Oligodendrocytes: 39.4" "Cancer enhanced" "Detected in many" "glioma: 8.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 31.5" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003905 Approved "Plasma membrane,Cytosol" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 76: Oligodendrocyte precursor - Unknown function" "Plasma membrane, Cytosol" "HPA003905: AB_1078922" "unprognostic (2.68e-1)" "unprognostic (2.33e-1)" "unprognostic (4.95e-3)" "prognostic unfavorable (2.88e-6)" "unprognostic (3.87e-2)" "unprognostic (8.58e-2)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (1.92e-1)" "unprognostic (1.70e-2)" "prognostic favorable (2.33e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (1.08e-4)" "unprognostic (2.83e-1)" "unprognostic (3.92e-2)" "unprognostic (6.95e-2)" GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.5" "Group enriched" "Detected in some" 5 "B-cells: 33.8;NK-cells: 36.7;T-cells: 76.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 11.2;lymphoma: 3.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Pancreas - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041025, HPA058306" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 6: Non-specific - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 7: T-cells - T-cell receptor" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" GPR176 Gm1012 ENSG00000166073 "G protein-coupled receptor 176" Q14439 15 39799008-39920266 "G-protein coupled receptors, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.6" "Cell type enhanced" "Detected in many" "Early spermatids: 26.5;Excitatory neurons: 30.9;Inhibitory neurons: 54.5;Oligodendrocyte precursor cells: 38.2;Pancreatic endocrine cells: 18.7;Sertoli cells: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039943, HPA039979" Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 8: Neurons - Neuronal signaling" "HPA039943: AB_10697711, HPA039979: AB_2676782" "unprognostic (4.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.99e-1)" "unprognostic (1.11e-1)" "unprognostic (4.24e-1)" "unprognostic (1.04e-2)" "unprognostic (2.75e-2)" "unprognostic (1.38e-3)" "unprognostic (9.32e-2)" "unprognostic (3.23e-2)" "unprognostic (2.74e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (9.38e-7)" "prognostic unfavorable (6.84e-5)" "unprognostic (2.23e-1)" "unprognostic (1.95e-1)" "unprognostic (3.26e-2)" GPR18 ENSG00000125245 "G protein-coupled receptor 18" Q14330 13 99254732-99261744 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 9.6;lymphoid tissue: 38.0;testis: 12.7" "Group enriched" "Detected in some" 4 "Early spermatids: 94.1;Late spermatids: 239.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 65.5;NK-cells: 53.1;T-cells: 42.0" "Group enriched" "Detected in some" 17 "Leukemia: 6.7;lymphoma: 26.6" "Adipose visceral - T-cells, Breast - T-cells, Kidney - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA013873 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 11: Late spermatids - Unknown function" "HPA013873: AB_1849285" "unprognostic (3.87e-6)" "unprognostic (1.31e-3)" "unprognostic (3.22e-2)" "unprognostic (1.31e-6)" "unprognostic (2.89e-1)" "unprognostic (7.55e-4)" "unprognostic (4.27e-5)" "unprognostic (3.45e-3)" "unprognostic (2.31e-3)" "unprognostic (5.43e-2)" "unprognostic (9.70e-2)" "unprognostic (4.03e-1)" "unprognostic (3.20e-6)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (6.92e-3)" GPR182 "ADMR, AM-R, G10D, hrhAMR" ENSG00000166856 "G protein-coupled receptor 182" O15218 12 56994492-56998447 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 16.6;testis: 5.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 194.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Sinusoid Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027037 Enhanced NA NA "Cluster 47: Spleen - Immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA027037: AB_1844622" "unprognostic (6.13e-2)" "unprognostic (6.23e-2)" "unprognostic (3.56e-2)" "unprognostic (5.88e-2)" "unprognostic (2.60e-2)" "unprognostic (3.30e-1)" "unprognostic (2.10e-4)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (4.94e-1)" "unprognostic (1.67e-2)" "unprognostic (8.13e-2)" "unprognostic (5.62e-3)" "unprognostic (9.31e-2)" "unprognostic (2.88e-2)" "unprognostic (1.42e-1)" "unprognostic (4.34e-3)" GPR183 EBI2 ENSG00000169508 "G protein-coupled receptor 183" P32249 13 99294539-99307399 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 111.2;lymphoid tissue: 82.2" "Cell type enhanced" "Detected in many" "dendritic cells: 4011.2;Langerhans cells: 3287.6;Macrophages: 936.4;monocytes: 866.8;Schwann cells: 952.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1054.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 14.9;lymphoma: 23.7;thyroid cancer: 22.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Thyroid - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB033690, HPA075590" Approved NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "CAB033690: AB_2114269, HPA075590: " "unprognostic (3.28e-3)" "prognostic favorable (9.77e-4)" "unprognostic (6.03e-2)" "unprognostic (4.61e-3)" "unprognostic (3.45e-1)" "unprognostic (7.11e-2)" "unprognostic (1.71e-1)" "unprognostic (6.29e-2)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (5.75e-2)" "unprognostic (2.33e-1)" "unprognostic (4.50e-3)" "unprognostic (4.49e-3)" "unprognostic (1.97e-3)" "unprognostic (9.31e-3)" "unprognostic (9.86e-3)" GPR19 ENSG00000183150 "G protein-coupled receptor 19" Q15760 12 12660890-12696207 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.8;pituitary gland: 7.6;testis: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 7.4;Early spermatids: 5.8;Excitatory neurons: 14.7;Inhibitory neurons: 14.9;Oligodendrocyte precursor cells: 14.6;Oligodendrocytes: 5.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.4" "Group enriched" "Detected in many" 15 "granulocytes: 2.9;T-cells: 6.4" "Cancer enhanced" "Detected in all" "testis cancer: 26.3" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013955 Uncertain NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA013955: AB_1849287" "unprognostic (1.92e-1)" "unprognostic (3.38e-2)" "unprognostic (1.72e-1)" "unprognostic (8.62e-5)" "unprognostic (1.60e-1)" "unprognostic (3.21e-1)" "unprognostic (8.25e-4)" "unprognostic (1.37e-1)" "unprognostic (1.73e-1)" "unprognostic (6.90e-2)" "unprognostic (1.45e-1)" "unprognostic (1.70e-2)" "unprognostic (2.67e-12)" "unprognostic (5.19e-2)" "unprognostic (1.38e-1)" "unprognostic (7.60e-2)" "unprognostic (1.60e-1)" GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356470-141367286 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 13 "Sertoli cells: 27.2;Smooth muscle cells: 22.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 18 "intermediate monocyte: 2.6;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 22 "monocytes: 4.3" "Low cancer specificity" "Detected in single" "Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Testis - Endothelial cells, Thyroid - Smooth muscle cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.1" HPA071337 Supported "Plasma membrane,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Smooth muscle cells - Signal transduction" "Plasma membrane" Cytosol "HPA071337: " "unprognostic (4.47e-2)" "unprognostic (2.64e-3)" "unprognostic (5.18e-2)" "unprognostic (2.00e-2)" "unprognostic (7.47e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (7.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.23e-2)" "unprognostic (4.07e-1)" GPR21 ENSG00000188394 "G protein-coupled receptor 21" Q99679 9 123033667-123035665 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.6" "Cell type enhanced" "Detected in single" "Smooth muscle cells: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA041651 Uncertain NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA041651: AB_10794673" "unprognostic (9.22e-3)" "unprognostic (1.46e-1)" GPR22 ENSG00000172209 "G protein-coupled receptor 22" Q99680 7 107470018-107475684 "G-protein coupled receptors, Predicted membrane proteins" "Cilium biogenesis/degradation" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 7.0;heart muscle: 7.9" "Group enriched" "Detected in some" 5 "Cardiomyocytes: 83.0;Excitatory neurons: 48.3;Inhibitory neurons: 49.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "Neuroblastoma: 1.9" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 79.0" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 68: Cardiomyocytes - Muscle contraction" "unprognostic (4.23e-2)" "unprognostic (1.25e-2)" "unprognostic (1.19e-1)" "unprognostic (5.52e-2)" "unprognostic (7.73e-2)" "unprognostic (1.00e-1)" "unprognostic (4.27e-3)" "unprognostic (1.62e-1)" "unprognostic (8.76e-3)" "unprognostic (5.48e-2)" "unprognostic (1.25e-1)" "unprognostic (5.85e-4)" "unprognostic (1.55e-1)" "unprognostic (7.53e-3)" "unprognostic (2.27e-3)" "unprognostic (2.04e-1)" GPR25 ENSG00000170128 "G protein-coupled receptor 25" O00155 1 200872981-200874178 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 4 "stomach 1: 1.9" "Group enriched" "Detected in some" 4 "Plasma cells: 9.9;T-cells: 6.3" "Cancer enhanced" "Detected in some" "stomach cancer: 1.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "memory CD4 T-cell: 27.6;T-reg: 44.3" "Group enriched" "Detected in many" 57 "B-cells: 14.5;T-cells: 44.3" "Cancer enhanced" "Detected in single" "lymphoma: 2.7" "Lung - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 47: Spleen - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" 27 "unprognostic (2.80e-3)" "unprognostic (1.73e-2)" "unprognostic (1.06e-1)" "unprognostic (1.25e-4)" "unprognostic (2.21e-3)" "unprognostic (4.49e-5)" "unprognostic (1.94e-1)" "unprognostic (1.47e-1)" "unprognostic (1.61e-1)" "unprognostic (1.23e-2)" "unprognostic (1.04e-1)" "unprognostic (9.03e-2)" "unprognostic (1.29e-6)" "unprognostic (1.48e-2)" "unprognostic (3.71e-2)" "unprognostic (2.42e-2)" "unprognostic (3.22e-6)" GPR26 ENSG00000154478 "G protein-coupled receptor 26" Q8NDV2 10 123666355-123697399 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "brain: 2.8" "Group enriched" "Detected in some" 6 "Excitatory neurons: 11.0;Horizontal cells: 8.2" "Cancer enriched" "Detected in single" 13 "breast cancer: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebral cortex: 81.5" HPA062736 Enhanced NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Neurons - Neuronal signaling" "HPA062736: AB_2684855" "unprognostic (4.15e-2)" "unprognostic (5.75e-2)" "unprognostic (3.42e-1)" "unprognostic (2.12e-1)" "unprognostic (9.09e-2)" "unprognostic (9.98e-2)" "unprognostic (2.12e-2)" "unprognostic (1.16e-2)" "unprognostic (1.12e-1)" GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71753855-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 8.7;Collecting duct cells: 9.7;Cone photoreceptor cells: 8.5;Glandular and luminal cells: 8.8;Granulosa cells: 15.8;Secretory cells: 9.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 2.8;neutrophil: 7.3" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.3" "Low cancer specificity" "Detected in many" "Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Neutrophils - Degranulation" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favorable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" GPR3 ACCA ENSG00000181773 "G protein-coupled receptor 3" P46089 1 27392622-27395814 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 5.2" "Cell type enhanced" "Detected in some" "Adipocytes: 5.4;Excitatory neurons: 2.5;Inhibitory neurons: 4.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Liver - Vascular Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" CAB006254 Uncertain NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "CAB006254: AB_425462" "unprognostic (4.42e-2)" "unprognostic (2.22e-1)" "unprognostic (4.05e-2)" "unprognostic (1.55e-2)" "unprognostic (1.38e-2)" "unprognostic (1.27e-1)" "unprognostic (7.30e-3)" "unprognostic (6.87e-2)" "unprognostic (2.97e-1)" "unprognostic (1.09e-1)" "unprognostic (5.94e-2)" "unprognostic (1.97e-1)" "unprognostic (1.46e-1)" "unprognostic (8.17e-2)" "unprognostic (2.07e-2)" "unprognostic (6.54e-2)" "unprognostic (1.03e-2)" GPR31 "12-HETER, HETER1" ENSG00000120436 "G protein-coupled receptor 31" O00270 6 167155247-167157980 "G-protein coupled receptors, Predicted membrane proteins" "Lipid metabolism" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.4" "Cell type enriched" "Detected in single" 5 "Schwann cells: 4.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA014014, HPA027108" Uncertain NA NA "Cluster 70: Lymphoid tissue - Immune response" "Cluster 28: Dendritic cells - Antigen presentation" "HPA014014: AB_1849292, HPA027108: AB_10601474" "unprognostic (9.92e-2)" "unprognostic (1.52e-1)" "unprognostic (1.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.42e-3)" "unprognostic (2.20e-3)" "unprognostic (5.95e-3)" "unprognostic (4.03e-2)" "unprognostic (3.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (8.10e-4)" "unprognostic (2.45e-1)" "unprognostic (6.01e-2)" GPR32 RVDR1 ENSG00000142511 "G protein-coupled receptor 32" O75388 19 50770464-50771732 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 32 "parathyroid gland: 56.2" "Group enriched" "Detected in some" 29 "Extravillous trophoblasts: 6.3;Syncytiotrophoblasts: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 30 "testis cancer: 2.9" "Not detected" "Not detected" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "unprognostic (4.77e-1)" GPR33 ENSG00000214943 "G protein-coupled receptor 33" Q49SQ1 14 31482875-31488039 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.6" "Lineage enhanced" "Detected in single" "dendritic cells: 2.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 55: Lymphoma - Immune response" "unprognostic (1.20e-1)" "unprognostic (8.10e-3)" "unprognostic (6.53e-4)" "unprognostic (9.13e-2)" "unprognostic (2.55e-1)" "unprognostic (2.10e-1)" GPR34 ENSG00000171659 "G protein-coupled receptor 34" Q9UPC5 X 41688973-41697275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 41.3" "Cell type enhanced" "Detected in some" "granulocytes: 52.3;Hofbauer cells: 220.5;Kupffer cells: 135.2;Macrophages: 126.6;Microglial cells: 51.9" "Cancer enhanced" "Detected in all" "glioma: 26.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "basophil: 326.2;eosinophil: 113.2" "Lineage enriched" "Detected in many" 24 "granulocytes: 326.2" "Cancer enhanced" "Detected in single" "lymphoma: 1.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010668, CAB025490" Uncertain Approved Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" Cytosol "CAB025490: , HPA010668: AB_1849294" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.44e-2)" "unprognostic (1.20e-1)" "unprognostic (3.74e-2)" "unprognostic (5.83e-3)" "unprognostic (5.13e-2)" "unprognostic (1.59e-2)" "unprognostic (9.81e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (3.96e-1)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (1.88e-3)" "unprognostic (3.18e-2)" GPR35 ENSG00000178623 "G protein-coupled receptor 35" Q9HC97 2 240605430-240633159 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 45.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 74.8;Intestinal goblet cells: 27.5;Langerhans cells: 42.6;monocytes: 55.1;Paneth cells: 31.5;Proximal enterocytes: 90.4" "Group enriched" "Detected in many" 4 "colorectal cancer: 20.7;pancreatic cancer: 6.9;stomach cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "classical monocyte: 31.0;eosinophil: 32.6;intermediate monocyte: 44.7;myeloid DC: 27.6;non-classical monocyte: 12.3" "Group enriched" "Detected in many" 16 "dendritic cells: 27.6;granulocytes: 32.6;monocytes: 44.7" "Cancer enhanced" "Detected in many" "Bile duct cancer: 32.8;colorectal cancer: 59.8;Gastric cancer: 38.3" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 5: Enterocytes - Absorption" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.53e-1)" "unprognostic (5.99e-2)" "unprognostic (3.94e-3)" "unprognostic (2.71e-2)" "prognostic unfavorable (5.86e-4)" "unprognostic (2.01e-1)" "unprognostic (2.07e-1)" "unprognostic (7.98e-2)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.59e-5)" "unprognostic (7.03e-3)" "unprognostic (1.30e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-3)" GPR37 "EDNRBL, hET(B)R-LP, PAELR" ENSG00000170775 "G protein-coupled receptor 37" O15354 7 124743885-124765792 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 109.1;retina: 37.9" "Group enriched" "Detected in many" 7 "Muller glia cells: 595.5;Oligodendrocytes: 302.4" "Group enriched" "Detected in many" 4 "glioma: 19.2;liver cancer: 5.7;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042903, HPA068009" Approved Approved "Nuclear membrane,Cytosol" No No 900000 "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 10: Muller glia cells - Visual perception" 17 "Nuclear membrane, Cytosol" "HPA042903: AB_2678219, HPA068009: AB_2685940" "unprognostic (2.47e-1)" "unprognostic (2.57e-1)" "unprognostic (2.46e-1)" "unprognostic (3.30e-2)" "unprognostic (7.29e-2)" "unprognostic (1.06e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (6.00e-5)" "unprognostic (6.19e-2)" "prognostic favorable (7.26e-4)" "unprognostic (6.54e-2)" "unprognostic (2.58e-1)" "unprognostic (3.16e-2)" "unprognostic (6.12e-3)" "unprognostic (2.10e-1)" "unprognostic (1.88e-1)" "unprognostic (1.71e-4)" GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122886-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 53.4" "Cell type enhanced" "Detected in some" "Astrocytes: 87.0;Muller glia cells: 55.9;Oligodendrocyte precursor cells: 83.5;Oligodendrocytes: 19.0;Schwann cells: 24.5" "Cancer enriched" "Detected in some" 57 "glioma: 36.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061629, HPA064454" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 76: Oligodendrocyte precursor - Unknown function" 49 "Nucleoplasm, Cell Junctions" "Vesicles, Plasma membrane" "HPA061629: , HPA064454: AB_2685268" "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-3)" "unprognostic (4.52e-1)" "unprognostic (8.20e-2)" "unprognostic (2.26e-4)" "unprognostic (5.83e-2)" "unprognostic (3.46e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.86e-3)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (3.49e-1)" GPR39 ENSG00000183840 "G protein-coupled receptor 39" O43194 2 132416805-132646582 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.4;Astrocytes: 11.5;Early spermatids: 19.7;Late spermatids: 19.6;Oligodendrocyte precursor cells: 17.5;Oocytes: 22.1;Spermatocytes: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA022111 Approved NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 45: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 70: Spermatocytes & Spermatids - Spermatid development" 1 "HPA022111: AB_1849298" "unprognostic (4.06e-2)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (1.50e-2)" "unprognostic (5.19e-2)" "unprognostic (1.85e-1)" "unprognostic (8.54e-3)" "unprognostic (3.81e-2)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "prognostic unfavorable (7.50e-4)" "unprognostic (2.28e-1)" "unprognostic (1.64e-1)" "unprognostic (3.72e-1)" "unprognostic (4.69e-2)" "unprognostic (1.25e-1)" "unprognostic (6.58e-3)" GPR4 ENSG00000177464 "G protein-coupled receptor 4" P46093 19 45589764-45602212 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 39.3" "Group enriched" "Detected in some" 6 "Adipocytes: 25.8;Endothelial cells: 33.1;Smooth muscle cells: 16.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ovarian cancer: 1.8;prostate cancer: 2.2;Rhabdoid: 3.3;Sarcoma: 4.3;thyroid cancer: 4.1" "Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014278 Uncertain NA NA "Cluster 7: Adipose tissue - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA014278: AB_1849300" "unprognostic (2.49e-2)" "unprognostic (6.62e-3)" "unprognostic (1.33e-2)" "unprognostic (2.93e-2)" "unprognostic (2.70e-1)" "unprognostic (1.31e-1)" "unprognostic (4.95e-2)" "prognostic unfavorable (9.19e-4)" "unprognostic (1.29e-1)" "unprognostic (6.23e-2)" "unprognostic (1.70e-1)" "unprognostic (4.66e-2)" "prognostic unfavorable (2.07e-5)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" "unprognostic (9.18e-2)" "unprognostic (2.49e-3)" GPR42 "FFAR3L, GPR41L, GPR42P" ENSG00000126251 "G protein-coupled receptor 42" O15529 19 35371068-35372962 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "granulocytes: 7.0;monocytes: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044681 Uncertain NA NA "Cluster 30: Granulocytes - Unknown function" 88 "HPA044681: AB_2679043" "unprognostic (1.73e-3)" "unprognostic (1.31e-4)" GPR45 "PSP24, PSP24A" ENSG00000135973 "G protein-coupled receptor 45" Q9Y5Y3 2 105241743-105243467 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.1" "Group enriched" "Detected in some" 24 "Early spermatids: 3.5;Late spermatids: 7.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Kidney cancer: 2.0" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA055940 Uncertain NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Late spermatids - Unknown function" "HPA055940: AB_2682977" "unprognostic (3.80e-3)" "unprognostic (5.92e-2)" "unprognostic (2.19e-3)" "unprognostic (4.71e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (6.87e-2)" "unprognostic (2.21e-1)" "unprognostic (1.13e-1)" "unprognostic (3.96e-1)" "unprognostic (1.61e-3)" "unprognostic (1.11e-2)" "unprognostic (3.13e-4)" "unprognostic (2.25e-1)" "unprognostic (2.76e-1)" "unprognostic (1.39e-1)" "unprognostic (3.99e-2)" GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176584-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "pituitary gland: 16.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 23.7" "Group enriched" "Detected in many" 4 "hypothalamus: 14.4;white matter: 5.0" "Region enriched" "Detected in single" 12 "hypothalamus: 6.6" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" 3 "Plasma membrane" Nucleoplasm "HPA049862: AB_2680920, HPA054678: AB_2682570" "unprognostic (8.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.15e-1)" GPR52 ENSG00000203737 "G protein-coupled receptor 52" Q9Y2T5 1 174447964-174449545 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "brain: 5.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 1.7;Horizontal cells: 1.9;Rod photoreceptor cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 6 "basal ganglia: 103.8" "Region enhanced" "Detected in all" "basal ganglia: 42.0" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (1.93e-1)" "unprognostic (1.15e-1)" "unprognostic (8.60e-2)" "unprognostic (2.61e-2)" "unprognostic (3.65e-1)" "unprognostic (2.27e-1)" "unprognostic (4.49e-1)" GPR55 ENSG00000135898 "G protein-coupled receptor 55" Q9Y2T6 2 230907318-230961066 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5;lymphoid tissue: 4.3;testis: 4.5" "Cell type enhanced" "Detected in some" "B-cells: 1.8;dendritic cells: 2.2;Excitatory neurons: 2.2;Intestinal goblet cells: 2.5;Langerhans cells: 4.1;Plasma cells: 2.1;T-cells: 6.0" "Low cancer specificity" "Detected in single" "Region enriched" "Detected in some" 4 "basal ganglia: 9.6" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.9;lymphoma: 4.7" "Prostate - T-cells, Skin - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 7: T-cells - T-cell receptor" "unprognostic (9.88e-4)" "unprognostic (2.60e-2)" "unprognostic (2.27e-1)" "unprognostic (4.24e-3)" "unprognostic (5.93e-2)" "unprognostic (1.12e-4)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.08e-1)" "unprognostic (2.34e-1)" "unprognostic (4.37e-2)" "unprognostic (3.18e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (1.13e-1)" "unprognostic (2.42e-2)" "unprognostic (4.26e-1)" GPR6 ENSG00000146360 "G protein-coupled receptor 6" P46095 6 109978256-109980720 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 30.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 54.5;hypothalamus: 14.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 11 "basal ganglia: 91.1" "Region enriched" "Detected in many" 4 "basal ganglia: 39.1" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 20: Enteroendocrine cells - Hormone signaling" "unprognostic (1.14e-2)" "unprognostic (1.59e-2)" "unprognostic (7.10e-3)" GPR61 BALGR ENSG00000156097 "G protein-coupled receptor 61" Q9BZJ8 1 109539872-109548406 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;pituitary gland: 2.6;retina: 2.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.0;Cone photoreceptor cells: 3.4;Excitatory neurons: 7.9;Horizontal cells: 8.8;Inhibitory neurons: 6.7;Schwann cells: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA007326, HPA026088" Supported NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" 16 "HPA007326: AB_1849308, HPA026088: AB_10602323" "unprognostic (1.70e-1)" "unprognostic (1.61e-1)" "unprognostic (1.91e-1)" "unprognostic (2.01e-1)" "unprognostic (4.40e-2)" "unprognostic (1.70e-2)" "unprognostic (7.51e-2)" "unprognostic (3.63e-3)" "unprognostic (2.94e-2)" "unprognostic (4.50e-2)" "unprognostic (1.46e-4)" "unprognostic (3.27e-1)" "unprognostic (4.08e-4)" "unprognostic (1.33e-1)" "unprognostic (1.07e-1)" "unprognostic (6.72e-2)" "unprognostic (3.85e-2)" GPR62 ENSG00000180929 "G protein-coupled receptor 62" Q9BZJ7 3 51955381-51957499 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 21.9" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 17.4" "Cancer enhanced" "Detected in single" "glioma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 1: Neuronal - Visual perception" "Cluster 51: Oligodendrocytes - Unknown function" "unprognostic (9.56e-3)" "unprognostic (3.32e-3)" "unprognostic (2.21e-1)" "unprognostic (6.38e-2)" "unprognostic (7.98e-2)" "unprognostic (1.66e-2)" "unprognostic (9.02e-2)" "unprognostic (6.49e-2)" "unprognostic (2.03e-2)" "unprognostic (6.17e-2)" "unprognostic (3.05e-2)" "unprognostic (1.26e-1)" "unprognostic (1.82e-5)" "unprognostic (3.64e-2)" "unprognostic (2.45e-1)" "unprognostic (1.16e-2)" "unprognostic (1.77e-2)" GPR63 "PSP24(beta), PSP24B" ENSG00000112218 "G protein-coupled receptor 63" Q9BZJ6 6 96794125-96837477 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early spermatids: 33.5;Excitatory neurons: 44.6;Inhibitory neurons: 19.3;Late spermatids: 30.3;Spermatocytes: 23.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 10.0" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039103 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 65: Neurons - Synaptic function" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039103: AB_10672841" "unprognostic (8.22e-2)" "unprognostic (2.77e-1)" "unprognostic (1.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.33e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (3.39e-1)" "unprognostic (2.53e-2)" "unprognostic (7.29e-3)" "unprognostic (3.00e-1)" "unprognostic (2.03e-3)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-2)" GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005135-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.5;lymphoid tissue: 9.4" "Cell type enhanced" "Detected in many" "dendritic cells: 341.9;granulocytes: 495.1;NK-cells: 379.4;T-cells: 187.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 3.6;lymphoma: 7.1" "Skeletal muscle - Macrophages, Testis - Early spermatids, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 19: NK-cells - Adaptive immune response" Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (8.56e-2)" "unprognostic (8.65e-3)" "unprognostic (1.98e-3)" "unprognostic (3.59e-3)" "unprognostic (3.10e-1)" "unprognostic (3.55e-3)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (4.99e-4)" "unprognostic (3.79e-1)" "unprognostic (4.46e-3)" "unprognostic (9.03e-2)" "unprognostic (3.80e-1)" GPR68 OGR1 ENSG00000119714 "G protein-coupled receptor 68" Q15743 14 91232532-91253925 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Amelogenesis imperfecta, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 11.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 8.5;Hofbauer cells: 15.6;Langerhans cells: 33.5;NK-cells: 10.2;T-cells: 14.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 22.9" "Group enriched" "Detected in many" 9 "NK-cells: 20.2;T-cells: 22.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 19: NK-cells - Adaptive immune response" "unprognostic (3.44e-1)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "prognostic favorable (3.06e-5)" "unprognostic (3.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.10e-2)" "unprognostic (1.58e-1)" "unprognostic (6.84e-2)" "unprognostic (9.63e-2)" "unprognostic (9.42e-2)" "unprognostic (3.73e-1)" "unprognostic (8.31e-9)" "unprognostic (1.70e-2)" "unprognostic (3.19e-2)" "unprognostic (9.44e-2)" "unprognostic (2.78e-3)" GPR75 WI-31133 ENSG00000119737 "G protein-coupled receptor 75" O95800 2 53852912-53859967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1;retina: 7.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 1.7;Gastric mucus-secreting cells: 1.2;Glandular and luminal cells: 1.4;Mucus glandular cells: 2.2;Salivary duct cells: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 37: Glandular & Luminal cells - Unknown function" "unprognostic (1.88e-1)" "unprognostic (2.39e-2)" "unprognostic (2.77e-1)" "unprognostic (4.44e-2)" "unprognostic (5.96e-2)" "unprognostic (5.27e-3)" "unprognostic (8.31e-3)" "unprognostic (2.59e-3)" "unprognostic (4.71e-2)" "unprognostic (2.20e-1)" "unprognostic (3.07e-4)" "unprognostic (1.10e-1)" "unprognostic (3.97e-3)" "unprognostic (8.23e-2)" "unprognostic (1.94e-1)" "unprognostic (3.38e-1)" "unprognostic (5.75e-2)" GPR78 ENSG00000155269 "G protein-coupled receptor 78" Q96P69 4 8558725-8619761 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "esophagus: 1.4;placenta: 2.9" "Cell type enriched" "Detected in some" 4 "Extravillous trophoblasts: 20.6" "Cancer enhanced" "Detected in single" "urothelial cancer: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bladder cancer: 5.1;testis cancer: 2.6" HPA013209 Uncertain NA NA "Cluster 58: Placenta - Pregnancy" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "HPA013209: AB_10601657" "unprognostic (6.41e-2)" "unprognostic (1.77e-2)" "unprognostic (1.17e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-2)" "unprognostic (3.70e-2)" "unprognostic (3.82e-4)" "unprognostic (6.46e-3)" "unprognostic (1.20e-1)" "unprognostic (3.80e-2)" "unprognostic (2.29e-1)" "unprognostic (4.88e-15)" "unprognostic (5.55e-3)" "unprognostic (3.93e-2)" "unprognostic (9.90e-3)" "unprognostic (8.15e-2)" GPR82 ENSG00000171657 "G protein-coupled receptor 82" Q96P67 X 41724181-41730130 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 2.6;lymphoid tissue: 6.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 15.3;Horizontal cells: 15.1;Kupffer cells: 31.8;Macrophages: 15.6;Rod photoreceptor cells: 16.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "eosinophil: 40.1;NK-cell: 10.8" "Group enriched" "Detected in many" 10 "granulocytes: 40.1;NK-cells: 10.8" "Not detected" "Not detected" "Liver - Kupffer cells, Pancreas - Macrophages, Prostate - Macrophages, Thyroid - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035914 Approved NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 58: Macrophages - Innate immune response" "HPA035914: AB_10670671" "unprognostic (5.62e-3)" "unprognostic (1.81e-2)" "unprognostic (4.65e-2)" "unprognostic (3.88e-3)" "unprognostic (1.15e-2)" "unprognostic (3.28e-2)" "unprognostic (4.62e-4)" "unprognostic (1.41e-3)" "unprognostic (2.12e-2)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (3.01e-1)" "unprognostic (7.45e-2)" "unprognostic (2.37e-2)" "unprognostic (2.26e-1)" "unprognostic (8.00e-3)" "unprognostic (1.18e-1)" GPR83 GPR72 ENSG00000123901 "G protein-coupled receptor 83" Q9NYM4 11 94377316-94401419 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 5 "brain: 15.4" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.1;Early spermatids: 1.0;Excitatory neurons: 2.5;Inhibitory neurons: 4.2" "Cancer enhanced" "Detected in some" "thyroid cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Thyroid - Thyroid glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 67.5" "Low region specificity" "Detected in many" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (6.74e-2)" "unprognostic (7.78e-3)" "unprognostic (8.58e-2)" "unprognostic (2.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.88e-1)" "unprognostic (6.36e-3)" "unprognostic (6.89e-2)" "unprognostic (6.03e-2)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "unprognostic (6.17e-2)" "unprognostic (1.47e-12)" "unprognostic (3.16e-1)" "unprognostic (1.64e-1)" "unprognostic (1.33e-2)" "unprognostic (8.28e-3)" GPR84 EX33 ENSG00000139572 "G protein-coupled receptor 84" Q9NQS5 12 54362445-54364487 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.5;urinary bladder: 15.2" "Group enriched" "Detected in some" 6 "Hofbauer cells: 28.2;Langerhans cells: 21.7;Macrophages: 32.1;monocytes: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 23 "basophil: 9.1;classical monocyte: 9.9;myeloid DC: 14.8;neutrophil: 6.0" "Group enriched" "Detected in many" 62 "dendritic cells: 14.8;granulocytes: 9.1;monocytes: 9.9" "Group enriched" "Detected in some" 6 "Leukemia: 3.9;lymphoma: 7.6" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in many" HPA027603 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Monocytes - Innate immune response" "HPA027603: AB_10612115" "unprognostic (5.40e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (2.36e-2)" "unprognostic (4.54e-2)" "unprognostic (6.16e-3)" "unprognostic (7.43e-2)" "unprognostic (9.29e-2)" "unprognostic (1.37e-1)" "unprognostic (2.34e-2)" "unprognostic (2.92e-1)" "unprognostic (1.36e-9)" "unprognostic (1.27e-1)" "unprognostic (4.42e-2)" "unprognostic (1.40e-1)" "unprognostic (9.44e-2)" GPR85 SREB2 ENSG00000164604 "G protein-coupled receptor 85" P60893 7 113078331-113087778 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 20.4;retina: 11.7;skeletal muscle: 30.6" "Group enriched" "Detected in many" 4 "Bipolar cells: 79.6;Early spermatids: 313.7;Horizontal cells: 86.9" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 7.9" "Liver - Kupffer cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 2: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Early spermatids - Unknown function" "unprognostic (3.80e-2)" "unprognostic (1.93e-2)" "unprognostic (6.98e-3)" "unprognostic (3.92e-2)" "unprognostic (2.68e-2)" "unprognostic (2.41e-2)" "unprognostic (9.90e-2)" "unprognostic (1.94e-1)" "unprognostic (6.09e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (1.34e-5)" "unprognostic (5.89e-3)" "unprognostic (9.99e-2)" "unprognostic (1.69e-1)" "unprognostic (1.23e-2)" GPR87 GPR95 ENSG00000138271 "G protein-coupled receptor 87" Q9BY21 3 151294086-151316820 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.9;skin 1: 31.8;vagina: 23.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 49.1;Basal respiratory cells: 141.2;Basal squamous epithelial cells: 48.5;Cytotrophoblasts: 57.4;Ionocytes: 60.0;Squamous epithelial cells: 50.7;Suprabasal keratinocytes: 64.2;Syncytiotrophoblasts: 217.7" "Group enriched" "Detected in many" 6 "cervical cancer: 44.1;head and neck cancer: 40.1;lung cancer: 22.0;urothelial cancer: 23.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.8;head and neck cancer: 95.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA066313 Approved "Nucleoplasm,Lipid droplets,Mitochondria" No No "Cluster 27: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 35: Respiratory epithelial cells - Unknown function" "Lipid droplets, Mitochondria" Nucleoplasm "HPA066313: AB_2685656" "unprognostic (5.81e-2)" "unprognostic (2.12e-1)" "unprognostic (4.07e-3)" "unprognostic (8.60e-2)" "unprognostic (1.28e-2)" "unprognostic (4.61e-3)" "unprognostic (3.28e-2)" "unprognostic (1.27e-1)" "prognostic unfavorable (4.62e-6)" "unprognostic (8.64e-2)" "unprognostic (1.50e-3)" "unprognostic (3.66e-4)" "unprognostic (8.73e-2)" "unprognostic (3.80e-2)" "unprognostic (2.17e-1)" GPR88 ENSG00000181656 "G protein-coupled receptor 88" Q9GZN0 1 100538139-100542021 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 78.8" "Cell type enriched" "Detected in some" 8 "Horizontal cells: 15.1" "Cancer enriched" "Detected in some" 9 "liver cancer: 12.0" "Region enriched" "Detected in all" 9 "basal ganglia: 200.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 10 "basal ganglia: 719.1" "Region enriched" "Detected in many" 42 "basal ganglia: 358.6" HPA007488 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA007488: AB_2667844" "unprognostic (1.65e-1)" "unprognostic (1.50e-1)" "unprognostic (8.30e-2)" "unprognostic (8.37e-3)" "unprognostic (5.41e-1)" "unprognostic (5.63e-2)" "unprognostic (1.82e-1)" "unprognostic (1.28e-1)" "unprognostic (1.03e-2)" "unprognostic (7.76e-2)" "unprognostic (8.23e-3)" "unprognostic (2.45e-1)" "unprognostic (3.93e-4)" "unprognostic (1.85e-2)" "unprognostic (5.56e-2)" "unprognostic (4.41e-1)" "unprognostic (1.35e-2)" GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 195.6;urinary bladder: 125.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1849.7;Alveolar cells type 2: 586.6;Club cells: 431.6;Distal enterocytes: 306.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 3.6" "Lineage enriched" "Detected in single" 13 "granulocytes: 3.6" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 57: Lung - Lung function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 72: Alveolar cells - Lung function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" GPRC5B RAIG-2 ENSG00000167191 "G protein-coupled receptor class C group 5 member B" Q9NZH0 16 19856691-19886167 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 225.6" "Cell type enhanced" "Detected in many" "Early spermatids: 103.5;Late spermatids: 279.1;Lymphatic endothelial cells: 89.2;Oligodendrocytes: 159.1;Sertoli cells: 89.8" "Cancer enhanced" "Detected in all" "glioma: 52.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 2.8" "Lineage enhanced" "Detected in single" "T-cells: 2.8" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Pancreas - Ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015247 Enhanced Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Late spermatids - Unknown function" Vesicles "Nucleoplasm, Nucleoli" "HPA015247: AB_1849323" "unprognostic (1.26e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.60e-3)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (3.97e-2)" "unprognostic (5.70e-2)" "unprognostic (1.42e-1)" "unprognostic (2.26e-2)" "unprognostic (2.76e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.30e-4)" "unprognostic (4.73e-2)" "unprognostic (1.06e-1)" "unprognostic (4.42e-3)" "unprognostic (6.78e-3)" GPRC5C RAIG-3 ENSG00000170412 "G protein-coupled receptor class C group 5 member C" Q9NQ84 17 74424851-74451653 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 188.1;stomach 1: 224.0" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 139.7;Hepatocytes: 171.7;Ionocytes: 146.5;Paneth cells: 183.3;Secretory cells: 157.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 7.9" "Group enriched" "Detected in many" 9 "dendritic cells: 7.9;monocytes: 3.8" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Thyroid - Thyroid glandular cells" "Region enriched" "Detected in all" 9 "cerebellum: 42.5" "Low region specificity" "Detected in all" HPA029776 Enhanced Uncertain "Nucleoplasm,Centriolar satellite,Cytosol" NA Yes 15000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 68: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Glandular & Luminal cells - Unknown function" "Centriolar satellite" "Nucleoplasm, Cytosol" "HPA029776: AB_10602324" "unprognostic (1.48e-1)" "unprognostic (3.35e-1)" "unprognostic (6.01e-2)" "unprognostic (2.37e-3)" "unprognostic (1.80e-2)" "unprognostic (1.09e-2)" "unprognostic (4.40e-2)" "unprognostic (1.57e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (9.61e-3)" "unprognostic (1.05e-1)" "prognostic favorable (1.58e-5)" "unprognostic (7.58e-2)" "unprognostic (3.70e-2)" "unprognostic (2.75e-2)" "unprognostic (1.54e-3)" GPRC5D ENSG00000111291 "G protein-coupled receptor class C group 5 member D" Q9NZD1 12 12940575-12952170 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "skin 1: 28.0" "Group enriched" "Detected in some" 4 "Early spermatids: 6.1;Gastric mucus-secreting cells: 4.1;Late spermatids: 6.5;Plasma cells: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 10 "memory B-cell: 14.7;naive B-cell: 4.9" "Lineage enriched" "Detected in single" 15 "B-cells: 14.7" "Cancer enriched" "Detected in many" 20 "Myeloma: 60.8" "Breast - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA071909 Approved NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 13: Skin - Cornification" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 61: Plasma cells - Immunoglobulins & histones" 24 "HPA071909: AB_2686470" "unprognostic (4.27e-2)" "unprognostic (8.58e-2)" "unprognostic (4.68e-2)" "unprognostic (2.02e-1)" "unprognostic (4.34e-2)" "prognostic favorable (5.09e-4)" "unprognostic (3.00e-5)" "unprognostic (4.06e-2)" "unprognostic (3.06e-2)" "unprognostic (5.53e-2)" "unprognostic (7.01e-2)" "unprognostic (2.27e-2)" "unprognostic (8.33e-3)" "unprognostic (9.54e-2)" "unprognostic (1.83e-1)" "unprognostic (1.11e-2)" "unprognostic (6.63e-2)" GPRC6A bA86F4.3 ENSG00000173612 "G protein-coupled receptor class C group 6 member A" Q5T6X5 6 116792085-116829083 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "Salivary duct cells: 21.4" "Cancer enriched" "Detected in single" 11 "renal cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Intercalated cells" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 20: Myeloma - Immune response" "Cluster 75: Serous glandular cells - Salivary secretion" "unprognostic (9.16e-2)" "unprognostic (2.48e-1)" "unprognostic (4.38e-3)" GRM1 "GPRC1A, mGlu1, MGLUR1, PPP1R85" ENSG00000152822 "Glutamate metabotropic receptor 1" Q13255 6 146027646-146437601 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 17.0;retina: 5.4" "Group enriched" "Detected in some" 6 "Excitatory neurons: 208.5;Inhibitory neurons: 132.7;Rod photoreceptor cells: 125.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015701 Approved Supported Approved Vesicles NA NA "Cluster 28: Neuronal - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 34: Neurons - Neuronal signaling" 1 Vesicles "HPA015701: AB_1853917" "unprognostic (1.04e-2)" "unprognostic (7.33e-2)" "unprognostic (3.73e-3)" "unprognostic (9.77e-3)" "unprognostic (6.75e-2)" "unprognostic (2.13e-1)" "unprognostic (1.09e-1)" "unprognostic (5.78e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (9.48e-3)" "unprognostic (7.92e-2)" "unprognostic (1.84e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (8.33e-3)" "unprognostic (9.76e-2)" GRM2 "GPRC1B, mGlu2, MGLUR2" ENSG00000164082 "Glutamate metabotropic receptor 2" Q14416 3 51707068-51718613 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 3.4;Excitatory neurons: 15.6;Horizontal cells: 7.6;Rod photoreceptor cells: 3.5;Spermatocytes: 3.2" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Bone cancer: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027868, HPA065166" Approved Supported NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 20 "HPA027868: , HPA065166: AB_2685425" "unprognostic (1.01e-1)" "unprognostic (8.61e-4)" "unprognostic (7.66e-2)" "unprognostic (7.29e-3)" "unprognostic (1.98e-1)" "unprognostic (3.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.27e-1)" "unprognostic (1.39e-2)" "unprognostic (2.05e-1)" "unprognostic (4.45e-1)" "unprognostic (1.74e-1)" "unprognostic (1.37e-2)" "unprognostic (1.35e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-2)" "unprognostic (1.19e-2)" GRM3 "GPRC1C, mGlu3, MGLUR3" ENSG00000198822 "Glutamate metabotropic receptor 3" Q14832 7 86643909-86864879 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "brain: 50.4" "Group enriched" "Detected in some" 19 "Astrocytes: 389.5;Excitatory neurons: 262.7;Oligodendrocytes: 957.1" "Cancer enriched" "Detected in single" 7 "glioma: 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 51: Oligodendrocytes - Unknown function" "unprognostic (2.05e-1)" "unprognostic (3.78e-2)" "unprognostic (1.90e-1)" "unprognostic (2.70e-3)" "unprognostic (3.16e-1)" "unprognostic (1.07e-3)" "unprognostic (6.99e-3)" "unprognostic (2.98e-1)" "unprognostic (2.71e-1)" "unprognostic (9.13e-3)" "unprognostic (1.88e-3)" "unprognostic (2.04e-1)" "unprognostic (3.91e-3)" "unprognostic (4.00e-2)" "unprognostic (9.34e-2)" "unprognostic (1.72e-3)" "unprognostic (1.12e-2)" GRM4 "GPRC1D, mGlu4, MGLUR4" ENSG00000124493 "Glutamate metabotropic receptor 4" Q14833 6 34018643-34155622 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 331 "brain: 276.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 9.1;Horizontal cells: 19.5;Inhibitory neurons: 10.4;Late spermatids: 3.5;Spermatogonia: 4.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.7" "Region enriched" "Detected in all" 7 "cerebellum: 171.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 1.3" "Pancreas - Alpha cells, Pancreas - Beta cells" "Region enhanced" "Detected in all" "cerebellum: 79.1" "Region enriched" "Detected in all" 5 "cerebellum: 178.6" CAB022096 Enhanced NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" "CAB022096: " "unprognostic (1.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.03e-1)" "unprognostic (7.00e-2)" "unprognostic (4.03e-2)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (3.56e-1)" "unprognostic (9.45e-2)" "unprognostic (2.08e-2)" "unprognostic (6.21e-3)" "unprognostic (2.44e-1)" "unprognostic (2.15e-11)" "unprognostic (5.32e-2)" "unprognostic (9.16e-2)" "unprognostic (6.57e-2)" "unprognostic (3.07e-1)" GRM5 "GPRC1E, mGlu5, MGLUR5, PPP1R86" ENSG00000168959 "Glutamate metabotropic receptor 5" P41594 11 88504576-89065982 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 14.4" "Group enriched" "Detected in some" 26 "Excitatory neurons: 872.0;Inhibitory neurons: 927.5;Oligodendrocyte precursor cells: 976.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Gallbladder cancer: 2.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Intracellular and membrane" Receptor NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 65: Neurons - Synaptic function" "unprognostic (1.94e-1)" "unprognostic (9.62e-2)" "unprognostic (9.57e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-1)" "unprognostic (7.16e-2)" "unprognostic (8.15e-4)" "unprognostic (3.43e-2)" GRM6 "CSNB1B, GPRC1F, mGlu6, MGLUR6" ENSG00000113262 "Glutamate metabotropic receptor 6" O15303 5 178977587-178996206 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Receptor, Transducer" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "retina: 41.3" "Cell type enriched" "Detected in some" 35 "Bipolar cells: 482.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Brain cancer: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014511 Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 25: Bipolar cells - Visual perception" "HPA014511: AB_2669025" "unprognostic (1.85e-1)" "unprognostic (1.54e-1)" "unprognostic (8.41e-2)" "unprognostic (1.27e-1)" "unprognostic (4.16e-1)" "unprognostic (2.25e-3)" "unprognostic (7.72e-2)" "unprognostic (2.32e-2)" "unprognostic (2.12e-3)" "unprognostic (6.27e-2)" "unprognostic (3.34e-4)" "unprognostic (2.58e-1)" "unprognostic (3.36e-4)" "unprognostic (1.23e-1)" "unprognostic (6.45e-2)" "unprognostic (7.59e-3)" "unprognostic (1.97e-1)" GRM7 "GLUR7, GPRC1G, mGlu7, MGLUR7, PPP1R87" ENSG00000196277 "Glutamate metabotropic receptor 7" Q14831 3 6770001-7741533 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Cardiomyopathy, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.5;parathyroid gland: 4.1" "Group enriched" "Detected in some" 15 "Excitatory neurons: 748.5;Inhibitory neurons: 568.5;Oligodendrocyte precursor cells: 1115.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015964 Uncertain Cytosol NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 34: Neurons - Neuronal signaling" Cytosol "HPA015964: " "unprognostic (2.04e-2)" "unprognostic (7.03e-3)" "unprognostic (1.43e-1)" "unprognostic (9.37e-2)" "unprognostic (8.48e-3)" "unprognostic (2.58e-1)" "unprognostic (7.30e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-1)" "unprognostic (1.78e-1)" "unprognostic (1.46e-2)" "unprognostic (2.54e-1)" "unprognostic (6.84e-6)" "unprognostic (1.45e-1)" "unprognostic (2.82e-2)" "unprognostic (5.43e-2)" "unprognostic (2.59e-2)" GRM8 "GLUR8, GPRC1H, mGlu8, MGLUR8" ENSG00000179603 "Glutamate metabotropic receptor 8" O00222 7 126438598-127253093 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "choroid plexus: 21.0" "Cell type enhanced" "Detected in some" "Early spermatids: 49.4;Excitatory neurons: 100.9;Inhibitory neurons: 128.7;Late spermatids: 76.3;Oligodendrocyte precursor cells: 30.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7" "Region enriched" "Detected in all" 4 "choroid plexus: 103.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 6.5" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051481 Uncertain NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 69: Neurons - Neuronal signaling" "HPA051481: AB_2681499" "unprognostic (4.57e-3)" "unprognostic (5.10e-4)" "unprognostic (1.21e-1)" "unprognostic (2.09e-2)" "unprognostic (1.83e-1)" "unprognostic (5.54e-2)" "unprognostic (2.06e-4)" "unprognostic (1.79e-1)" "unprognostic (8.90e-2)" "unprognostic (1.31e-2)" "unprognostic (1.68e-1)" "unprognostic (1.69e-1)" "unprognostic (3.12e-2)" "unprognostic (1.69e-1)" "unprognostic (1.10e-1)" "unprognostic (1.32e-2)" "unprognostic (1.12e-2)" GRPR "BB2, BB2R, BRS2" ENSG00000126010 "Gastrin releasing peptide receptor" P30550 X 16123565-16153518 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "pancreas: 19.6" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 6.0;Oocytes: 7.4" "Cancer enriched" "Detected in some" 4 "breast cancer: 6.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 12.1;Rhabdoid: 7.9" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in all" HPA069604 Supported "Plasma membrane" NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 65: Neurons - Synaptic function" "Plasma membrane" "HPA069604: AB_2686158" "unprognostic (3.32e-2)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (2.87e-1)" "unprognostic (9.17e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (5.59e-2)" "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-1)" "unprognostic (2.86e-2)" HCAR1 "FKSG80, GPR104, GPR81, HCA1, LACR1, TA-GPCR" ENSG00000196917 "Hydroxycarboxylic acid receptor 1" Q9BXC0 12 122726076-122730844 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 11.1;parathyroid gland: 39.0" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 24.6;Breast glandular cells: 7.5;Breast myoepithelial cells: 4.6;Early spermatids: 8.3;Extravillous trophoblasts: 4.2;Late spermatids: 7.0" "Cancer enhanced" "Detected in many" "breast cancer: 7.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 16.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" NA NA "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Basal prostatic cells - Lipid metabolism" "prognostic unfavorable (3.61e-5)" "unprognostic (8.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-2)" "unprognostic (3.80e-4)" "unprognostic (5.43e-4)" "unprognostic (1.41e-1)" "unprognostic (7.74e-2)" "unprognostic (2.22e-1)" "unprognostic (6.85e-3)" "unprognostic (1.26e-1)" "unprognostic (2.66e-3)" "unprognostic (2.14e-2)" "unprognostic (2.51e-1)" "unprognostic (2.38e-1)" "unprognostic (1.87e-2)" HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 39.7;skin 1: 29.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 55.7;Basal prostatic cells: 154.4;Basal respiratory cells: 46.7;Basal squamous epithelial cells: 98.6;Langerhans cells: 141.4;Suprabasal keratinocytes: 65.7" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 12.1" "Immune cell enriched" "Detected in many" 5 "neutrophil: 177.3" "Lineage enriched" "Detected in many" 7 "granulocytes: 177.3" "Cancer enhanced" "Detected in some" "Bladder cancer: 21.1;Esophageal cancer: 21.1;head and neck cancer: 40.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - NK-cells (Lung), Skin - Keratinocyte (other), Testis - Late spermatids" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 74: Neutrophils - Degranulation" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.1;esophagus: 16.3;lymphoid tissue: 19.2;skin 1: 16.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 78.8;Basal prostatic cells: 190.1;Basal respiratory cells: 53.3;Basal squamous epithelial cells: 138.3;Langerhans cells: 71.4;monocytes: 57.9;Squamous epithelial cells: 45.4;Suprabasal keratinocytes: 87.0" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in some" 5 "cerebral cortex: 10.1" "Group enriched" "Detected in many" 6 "basophil: 58.8;neutrophil: 177.8;non-classical monocyte: 84.6" "Group enriched" "Detected in many" 50 "granulocytes: 177.8;monocytes: 84.6" "Cancer enhanced" "Detected in some" "Bladder cancer: 7.3;Gallbladder cancer: 6.8;head and neck cancer: 10.4" "Adipose visceral - Adipocytes (Visceral), Lung - NK-cells (Lung), Prostate - Urothelial cells, Skin - Keratinocyte (other)" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" HCRTR1 "ORXR1, OX1R, OXR1" ENSG00000121764 "Hypocretin receptor 1" O43613 1 31617686-31632518 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "adrenal gland: 1.1" "Cell type enriched" "Detected in single" 4 "Late spermatids: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA014018 Approved NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 63: Late spermatids - Spermatogenesis" 1 "HPA014018: AB_1854810" "unprognostic (2.96e-2)" "unprognostic (2.34e-2)" "unprognostic (7.86e-3)" "unprognostic (3.72e-3)" "unprognostic (2.42e-1)" "unprognostic (3.45e-3)" "unprognostic (2.54e-5)" "unprognostic (3.58e-2)" "unprognostic (4.17e-2)" "unprognostic (1.19e-1)" "unprognostic (2.28e-1)" "unprognostic (2.93e-1)" "unprognostic (3.77e-3)" "unprognostic (2.16e-2)" "unprognostic (1.02e-1)" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" HCRTR2 "ORXR2, OX2R, OXR2" ENSG00000137252 "Hypocretin receptor 2" O43614 6 55106460-55282617 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.3;Inhibitory neurons: 17.6;Peritubular cells: 4.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054516 Enhanced NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 65: Neurons - Synaptic function" 1 "HPA054516: AB_2682513" "unprognostic (4.86e-1)" "unprognostic (2.69e-2)" "unprognostic (1.86e-2)" "unprognostic (2.32e-1)" "unprognostic (7.45e-2)" "unprognostic (7.39e-2)" HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 31.6;Excitatory neurons: 33.5;Glandular and luminal cells: 39.2;Granulosa cells: 43.7;Secretory cells: 62.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Kupffer cells, Thyroid - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 37: Glandular & Luminal cells - Unknown function" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" HRH2 ENSG00000113749 "Histamine receptor H2" P25021 5 175658030-175710756 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.9;heart muscle: 25.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.9;Excitatory neurons: 60.1;Hofbauer cells: 28.8;Kupffer cells: 38.0;Macrophages: 43.7;Oocytes: 23.5;Smooth muscle cells: 34.0" "Group enriched" "Detected in many" 5 "melanoma: 2.9;renal cancer: 4.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 106.4;neutrophil: 141.7" "Group enriched" "Detected in many" 5 "granulocytes: 141.7;monocytes: 40.9" "Cancer enhanced" "Detected in some" "Leukemia: 7.1;Myeloma: 3.5;skin cancer: 3.7" "Liver - Neutrophils, Lung - Neutrophil_2, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA013770 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA013770: AB_1851086" "unprognostic (8.56e-3)" "unprognostic (1.62e-1)" "unprognostic (6.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" "unprognostic (9.93e-2)" "unprognostic (5.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-1)" "unprognostic (3.71e-3)" "unprognostic (2.01e-2)" "unprognostic (1.97e-2)" "unprognostic (1.97e-3)" "unprognostic (1.77e-2)" HRH3 GPCR97 ENSG00000101180 "Histamine receptor H3" Q9Y5N1 20 62214960-62220278 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "brain: 54.1" "Group enriched" "Detected in some" 4 "Horizontal cells: 15.7;Inhibitory neurons: 22.7" "Cancer enhanced" "Detected in single" "glioma: 0.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "lung cancer: 5.0;Neuroblastoma: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (1.56e-1)" "unprognostic (3.22e-1)" "unprognostic (4.15e-2)" "unprognostic (1.79e-1)" "unprognostic (2.77e-2)" "unprognostic (1.62e-2)" "unprognostic (7.30e-2)" "unprognostic (3.17e-4)" "unprognostic (2.40e-1)" "unprognostic (3.66e-3)" "unprognostic (3.30e-1)" "unprognostic (3.59e-2)" HRH4 "AXOR35, GPCR105, GPRv53, H4R, HH4R" ENSG00000134489 "Histamine receptor H4" Q9H3N8 18 24460637-24479961 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "granulocytes: 5.1;Langerhans cells: 1.1;Melanocytes: 1.7;Spermatocytes: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 123 "basophil: 212.9;eosinophil: 61.3" "Lineage enriched" "Detected in many" 191 "granulocytes: 212.9" "Not detected" "Not detected" "Skin - Mast cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA035009 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 48: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Granulocytes - Unknown function" "HPA035009: AB_10671507" "unprognostic (1.88e-1)" "unprognostic (2.62e-1)" "unprognostic (4.68e-2)" "unprognostic (9.83e-6)" "unprognostic (1.31e-2)" "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (8.96e-2)" "unprognostic (2.20e-1)" "unprognostic (3.30e-1)" "unprognostic (7.25e-2)" "unprognostic (2.91e-1)" "unprognostic (6.65e-7)" "unprognostic (1.89e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-4)" "unprognostic (7.70e-2)" HTR1A "5-HT1A, ADRB2RL1, ADRBRL1" ENSG00000178394 "5-hydroxytryptamine receptor 1A" P08908 5 63957874-63962507 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 2.0;ovary: 1.4" "Group enriched" "Detected in some" 6 "Leydig cells: 6.4;Ovarian stromal cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Rhabdoid: 8.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA018073 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 6: Ovarian stromal cells - Transcription" 2 "HPA018073: AB_1856704" "unprognostic (1.81e-1)" HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9;placenta: 6.4;stomach 1: 4.9" "Cell type enhanced" "Detected in some" "Horizontal cells: 1.9;Smooth muscle cells: 1.2" "Group enriched" "Detected in some" 4 "pancreatic cancer: 0.7;stomach cancer: 0.8;testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Adrenocortical cancer: 8.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Lung - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Late spermatids" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 12.0" HPA028808 Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Smooth muscle cells - Muscle contraction" 2 "Plasma membrane" "Endoplasmic reticulum" "HPA028808: AB_2672782" "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" HTR1D "5-HT1D, HT1DA, HTRL, RDC4" ENSG00000179546 "5-hydroxytryptamine receptor 1D" P28221 1 23191895-23217502 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 7.0;intestine: 8.3" "Group enriched" "Detected in some" 5 "Cholangiocytes: 5.7;Proximal enterocytes: 7.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "midbrain: 25.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 10.6" "Colon - Colon enteroendocrine cells, Pancreas - Ductal cells, Testis - Late spermatids" NA NA "Cluster 25: Small intestine - Absorption" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 22: Proximal enterocytes - Digestion" "unprognostic (1.73e-2)" "unprognostic (8.69e-3)" "unprognostic (8.86e-3)" "unprognostic (2.03e-1)" "unprognostic (2.65e-2)" "unprognostic (5.97e-4)" "prognostic unfavorable (1.86e-4)" "unprognostic (3.87e-3)" "unprognostic (8.88e-2)" "unprognostic (4.00e-2)" "prognostic unfavorable (5.30e-4)" "unprognostic (3.17e-2)" "unprognostic (3.28e-6)" "unprognostic (9.14e-2)" "unprognostic (2.27e-1)" "unprognostic (2.45e-1)" "unprognostic (8.02e-3)" HTR1E 5-HT1E ENSG00000168830 "5-hydroxytryptamine receptor 1E" P28566 6 86937528-87016679 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.3;ovary: 4.1" "Group enriched" "Detected in some" 18 "Excitatory neurons: 121.1;Inhibitory neurons: 99.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 2.3" "Colon - Colon enteroendocrine cells, Stomach - Chief cells" "Low region specificity" "Detected in many" HPA004931 Approved NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" 2 "HPA004931: AB_1856706" "unprognostic (2.25e-2)" "unprognostic (1.32e-1)" "unprognostic (6.29e-2)" "unprognostic (4.52e-2)" "unprognostic (1.25e-1)" HTR1F "5-HT1F, HTR1EL" ENSG00000179097 "5-hydroxytryptamine receptor 1F" P30939 3 87792706-87993839 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.7;retina: 3.5" "Group enriched" "Detected in some" 6 "Excitatory neurons: 224.7;Inhibitory neurons: 75.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.4;Leukemia: 1.3;thyroid cancer: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005555 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Neurons - Neuronal signaling" "HPA005555: AB_1856708" "unprognostic (1.66e-1)" "unprognostic (2.62e-1)" "unprognostic (2.58e-1)" "unprognostic (9.03e-2)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (4.78e-1)" "unprognostic (1.58e-1)" "unprognostic (2.77e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (9.80e-2)" "unprognostic (2.67e-6)" "unprognostic (1.25e-4)" "unprognostic (1.55e-2)" "unprognostic (3.33e-2)" "unprognostic (3.31e-2)" HTR2A "5-HT2A, HTR2" ENSG00000102468 "5-hydroxytryptamine receptor 2A" P28223 13 46831546-46897076 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Behavior, Host-virus interaction" "G-protein coupled receptor, Host cell receptor for virus entry, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 18.8" "Cell type enriched" "Detected in some" 8 "Excitatory neurons: 79.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bile duct cancer: 2.6" "Prostate - Fibroblasts, Thyroid - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014011 Enhanced NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 2 "HPA014011: AB_1856709" "unprognostic (8.01e-2)" "unprognostic (2.71e-2)" "unprognostic (9.49e-2)" "unprognostic (7.40e-2)" "unprognostic (2.78e-1)" "unprognostic (1.99e-1)" "unprognostic (2.70e-2)" "unprognostic (4.31e-2)" "unprognostic (5.27e-2)" "unprognostic (3.97e-2)" "unprognostic (2.61e-1)" "unprognostic (2.90e-1)" "unprognostic (9.94e-5)" "unprognostic (4.78e-3)" "unprognostic (2.54e-1)" "unprognostic (2.91e-2)" "unprognostic (8.28e-2)" HTR2B "5-HT(2B), 5-HT2B" ENSG00000135914 "5-hydroxytryptamine receptor 2B" P41595 2 231108230-231125042 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 16.8;cervix: 20.7;endometrium 1: 18.2;smooth muscle: 16.2" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 16.5;Microglial cells: 4.5;Peritubular cells: 4.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 1.9;T-reg: 1.0" "Group enriched" "Detected in many" 15 "granulocytes: 1.9;T-cells: 1.0" "Group enriched" "Detected in some" 7 "Rhabdoid: 18.6;skin cancer: 13.6" "Kidney - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA012867, HPA063658" Enhanced Supported Nucleoplasm NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: Endometrial stromal cells - Transcription" 2 Nucleoplasm "HPA012867: AB_1856710, HPA063658: AB_2685079" "unprognostic (1.86e-1)" "unprognostic (3.55e-2)" "unprognostic (1.20e-3)" "unprognostic (1.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.53e-2)" "unprognostic (1.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.15e-4)" "unprognostic (3.59e-1)" "unprognostic (2.17e-2)" "unprognostic (1.42e-3)" "unprognostic (7.44e-4)" "unprognostic (1.81e-1)" "unprognostic (1.17e-1)" "unprognostic (1.14e-2)" HTR2C "5-HT2C, 5HTR2C, HTR1C" ENSG00000147246 "5-hydroxytryptamine receptor 2C" P28335 X 114584078-114910061 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 146 "brain: 28.1;choroid plexus: 107.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 22.9;Inhibitory neurons: 52.3;Oligodendrocyte precursor cells: 9.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.9" "Region enriched" "Detected in all" 12 "choroid plexus: 620.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.5;Myeloma: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 69: Neurons - Neuronal signaling" 12 "unprognostic (2.14e-1)" "unprognostic (6.09e-3)" "unprognostic (9.54e-2)" "unprognostic (3.47e-2)" "unprognostic (2.89e-2)" "unprognostic (3.42e-2)" "unprognostic (9.22e-4)" "unprognostic (1.37e-1)" "unprognostic (6.84e-2)" HTR4 5-HT4 ENSG00000164270 "5-hydroxytryptamine receptor 4" Q13639 5 148446042-148677235 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 2.9;heart muscle: 4.4;intestine: 8.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 40.6;Inhibitory neurons: 42.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Rhabdoid: 2.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040591 Enhanced NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 8: Neurons - Neuronal signaling" 2 "HPA040591: AB_2677028" "unprognostic (1.12e-1)" "unprognostic (4.60e-2)" "unprognostic (7.74e-2)" "unprognostic (2.37e-1)" "unprognostic (5.02e-2)" "unprognostic (3.77e-2)" "unprognostic (4.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (3.40e-2)" "unprognostic (2.25e-1)" "unprognostic (4.49e-2)" "unprognostic (8.83e-5)" HTR5A 5-HT5A ENSG00000157219 "5-hydroxytryptamine receptor 5A" P47898 7 155070324-155087392 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 19 "brain: 15.2" "Cell type enhanced" "Detected in some" "Early spermatids: 10.8;Excitatory neurons: 7.3;Inhibitory neurons: 9.6;Late spermatids: 12.2;Sertoli cells: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid - Parafollicular cells" "Low region specificity" "Detected in all" CAB017467 Approved NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 11: Neuronal - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" "CAB017467: AB_2122566" "unprognostic (1.62e-2)" "unprognostic (1.15e-1)" HTR6 "5-HT6, 5-HT6R" ENSG00000158748 "5-hydroxytryptamine receptor 6" P50406 1 19664875-19680966 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 3.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 1.6;Spermatogonia: 1.1" "Cancer enhanced" "Detected in single" "renal cancer: 0.6" "Region enhanced" "Detected in many" "basal ganglia: 22.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.0;Rhabdoid: 3.2" "Low region specificity" "Detected in many" HPA068165 Uncertain NA NA "Cluster 11: T-cells - Unknown function" "Cluster 33: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Neurons - Neuronal signaling" 3 "HPA068165: " "unprognostic (2.34e-2)" "unprognostic (1.84e-1)" "unprognostic (7.19e-3)" "unprognostic (3.84e-5)" "unprognostic (1.38e-4)" "unprognostic (2.69e-2)" "unprognostic (1.36e-1)" "unprognostic (2.80e-2)" "unprognostic (1.03e-1)" "unprognostic (5.33e-3)" "unprognostic (8.63e-2)" "unprognostic (5.47e-4)" "unprognostic (1.28e-1)" "unprognostic (2.49e-1)" "unprognostic (6.13e-3)" "unprognostic (2.02e-1)" HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "parathyroid gland: 12.7;testis: 8.5" "Cell type enhanced" "Detected in some" "Early spermatids: 9.2;Excitatory neurons: 5.7;Inhibitory neurons: 23.4;Macrophages: 3.6;Spermatocytes: 10.9" "Group enriched" "Detected in some" 5 "cervical cancer: 0.9;head and neck cancer: 3.3;lung cancer: 0.9;urothelial cancer: 1.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA073617" Approved Supported Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 24: Parathyroid gland - Vesicular transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 8: Neurons - Neuronal signaling" 1 "Plasma membrane" "Nuclear speckles, Cytosol" "CAB022708: , HPA073617: AB_2732228" "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (4.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (1.71e-2)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (4.58e-3)" "unprognostic (3.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921005 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.6;pancreas: 1.3;pituitary gland: 1.1" "Cell type enriched" "Detected in some" 11 "Extravillous trophoblasts: 52.4" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 13.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 4: Extravillous trophoblasts - Unknown function" 1 "Plasma membrane" Vesicles "HPA007156: , HPA071913: AB_2686471" "unprognostic (1.54e-1)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.15e-1)" "unprognostic (8.46e-3)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "prognostic unfavorable (3.33e-6)" "unprognostic (1.87e-1)" "unprognostic (8.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" LGR4 GPR48 ENSG00000205213 "Leucine rich repeat containing G protein-coupled receptor 4" Q9BXB1 11 27365961-27472790 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Differentiation, Immunity, Innate immunity, Spermatogenesis, Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 193.8;Glandular and luminal cells: 134.5;Syncytiotrophoblasts: 120.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Skin - Outer root sheath cells, Testis - Sertoli cells, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030267, HPA054350" Uncertain Approved "Centriolar satellite" NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Centriolar satellite" "HPA030267: AB_10610004, HPA054350: " "unprognostic (5.27e-3)" "unprognostic (5.18e-2)" "unprognostic (4.64e-3)" "unprognostic (1.59e-1)" "unprognostic (4.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "unprognostic (2.00e-2)" "unprognostic (4.63e-2)" "unprognostic (5.84e-3)" "unprognostic (2.10e-1)" "prognostic favorable (2.00e-7)" "unprognostic (5.01e-1)" "unprognostic (3.59e-1)" "unprognostic (3.54e-2)" "unprognostic (1.76e-1)" LGR5 "FEX, GPR49, GPR67, HG38" ENSG00000139292 "Leucine rich repeat containing G protein-coupled receptor 5" O75473 12 71439798-71586310 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 16.3;placenta: 18.4;skeletal muscle: 21.5" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 51.9;Glandular and luminal cells: 73.9;Oligodendrocyte precursor cells: 42.4;Oligodendrocytes: 97.7;Syncytiotrophoblasts: 25.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 26.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 28.1" "Breast - Fibroblasts" "Region enriched" "Detected in many" 8 "olfactory bulb: 34.1" "Low region specificity" "Detected in many" HPA012530 Approved Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 14: Skeletal muscle - Muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 37: Glandular & Luminal cells - Unknown function" 1 "Golgi apparatus" Nucleoplasm "HPA012530: AB_1849329" "unprognostic (5.19e-2)" "unprognostic (3.79e-1)" "unprognostic (3.30e-1)" "unprognostic (1.02e-2)" "unprognostic (1.59e-1)" "unprognostic (2.49e-3)" "unprognostic (1.52e-1)" "prognostic favorable (5.09e-4)" "unprognostic (1.46e-1)" "unprognostic (2.60e-1)" "unprognostic (3.71e-1)" "unprognostic (8.10e-2)" "unprognostic (2.01e-5)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (2.28e-2)" "unprognostic (6.25e-3)" LGR6 FLJ14471 ENSG00000133067 "Leucine rich repeat containing G protein-coupled receptor 6" Q9HBX8 1 202193799-202319781 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 17.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 5.6;Basal squamous epithelial cells: 10.4;Breast myoepithelial cells: 8.2;Cardiomyocytes: 9.3;NK-cells: 10.0;Secretory cells: 11.0;Smooth muscle cells: 6.3;Spermatocytes: 5.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "gdT-cell: 15.5;memory CD8 T-cell: 9.1;naive CD8 T-cell: 4.8" "Lineage enriched" "Detected in single" 37 "T-cells: 15.5" "Cancer enhanced" "Detected in many" "Bile duct cancer: 6.9;colorectal cancer: 8.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids" "Region enriched" "Detected in many" 9 "olfactory bulb: 24.4" "Low region specificity" "Detected in many" HPA008556 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 44: Testis - Spermatogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA008556: " "unprognostic (4.72e-3)" "unprognostic (5.29e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (1.08e-1)" "unprognostic (5.13e-2)" "unprognostic (9.23e-2)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (4.01e-2)" "unprognostic (7.89e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-3)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (7.83e-2)" LHCGR "HHG, LCGR, LGR2, LHR, ULG5" ENSG00000138039 "Luteinizing hormone/choriogonadotropin receptor" P22888 2 48686774-48755730 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.1;testis: 2.1" "Cell type enhanced" "Detected in some" "Leydig cells: 1.0;Microglial cells: 6.3;Oligodendrocyte precursor cells: 1.9;Proximal tubular cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009814, HPA073668" Uncertain Supported "Plasma membrane,Centriolar satellite" NA NA "Cluster 74: Spermatids - Flagellum assembly" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 6: Ovarian stromal cells - Transcription" "Plasma membrane" "Centriolar satellite" "CAB009814: AB_2135467, HPA073668: " "unprognostic (8.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.14e-2)" "unprognostic (2.97e-2)" "unprognostic (2.24e-2)" "unprognostic (5.22e-2)" LPAR1 "edg-2, EDG2, Gpcr26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038470 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 232.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 583.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 8.7;eosinophil: 18.4" "Group enriched" "Detected in many" 6 "granulocytes: 18.4;monocytes: 8.7" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 68.7" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 51: Oligodendrocytes - Unknown function" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" LPAR2 "EDG-4, EDG4, LPA2" ENSG00000064547 "Lysophosphatidic acid receptor 2" Q9HBW0 19 19623655-19628930 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 35.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA019616 Approved NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" 2 "HPA019616: AB_1847988" "unprognostic (1.60e-2)" "unprognostic (1.83e-3)" "unprognostic (6.39e-2)" "unprognostic (1.19e-2)" "unprognostic (1.05e-1)" "unprognostic (2.29e-3)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (2.32e-1)" "unprognostic (1.05e-3)" "unprognostic (8.07e-2)" "unprognostic (6.03e-2)" "prognostic unfavorable (1.61e-7)" "prognostic favorable (1.43e-4)" "unprognostic (2.40e-1)" "unprognostic (5.87e-2)" "unprognostic (2.29e-2)" LPAR3 "Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3" ENSG00000171517 "Lysophosphatidic acid receptor 3" Q9UBY5 1 84811602-84893206 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 39.1;Ciliated cells: 27.0;Glandular and luminal cells: 50.5;Prostatic glandular cells: 58.8;Secretory cells: 21.1;Sertoli cells: 29.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 21.4" "Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA013421 Supported "Plasma membrane" NA NA "Cluster 8: Ciliated cells - Cilium organization" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Glandular & Luminal cells - Unknown function" 46 "Plasma membrane" "HPA013421: AB_1847990" "unprognostic (2.85e-2)" "unprognostic (1.67e-1)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (2.72e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "prognostic favorable (4.31e-5)" "unprognostic (1.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.13e-4)" "unprognostic (4.11e-2)" "unprognostic (1.19e-1)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78758714 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 9.6;Fibroblasts: 4.3;Leydig cells: 19.9;Mucus glandular cells: 11.6;Ovarian stromal cells: 4.2" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 7.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 7.8" "Cancer enhanced" "Detected in some" "Bone cancer: 2.0;testis cancer: 2.5" "Thyroid - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Neuronal - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 6: Ovarian stromal cells - Transcription" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" LPAR5 "GPR92, GPR93, KPG_010, LPA5" ENSG00000184574 "Lysophosphatidic acid receptor 5" Q9H1C0 12 6618835-6635960 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 20.3" "Cell type enhanced" "Detected in many" "B-cells: 25.0;Distal enterocytes: 23.3;Hofbauer cells: 34.1;Microglial cells: 32.2;Paneth cells: 23.5;Suprabasal keratinocytes: 20.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 18.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 84.1;T-cells: 66.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Liver - Kupffer cells, Skeletal muscle - Macrophages, Skin - Keratinocyte (other)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA013170 Approved NA NA "Cluster 24: Non-specific - Transcription" "Cluster 29: Squamous epithelium - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: B-cells - B-cell function" "HPA013170: AB_1849314" "unprognostic (1.94e-1)" "unprognostic (6.43e-2)" "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (1.37e-1)" "unprognostic (5.95e-2)" "unprognostic (3.45e-1)" "unprognostic (1.41e-2)" "unprognostic (3.62e-3)" "unprognostic (2.07e-1)" "unprognostic (6.27e-2)" "unprognostic (7.99e-3)" "unprognostic (5.43e-1)" "prognostic favorable (6.56e-5)" "unprognostic (7.43e-2)" LPAR6 "P2RY5, P2Y5" ENSG00000139679 "Lysophosphatidic acid receptor 6" P43657 13 48389567-48444704 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 284.3;Basal squamous epithelial cells: 246.4;Early spermatids: 265.5;Langerhans cells: 907.0;Late spermatids: 359.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028934 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Dendritic cells - Antigen presentation" 4 "HPA028934: AB_2672833" "unprognostic (1.19e-1)" "unprognostic (4.10e-1)" "unprognostic (8.82e-2)" "unprognostic (9.30e-3)" "unprognostic (2.31e-1)" "unprognostic (5.57e-2)" "unprognostic (7.40e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.07e-2)" "unprognostic (8.00e-2)" "unprognostic (2.63e-1)" "unprognostic (2.46e-1)" "prognostic unfavorable (3.60e-4)" "unprognostic (6.54e-2)" "unprognostic (3.81e-2)" "unprognostic (2.09e-2)" "unprognostic (1.94e-2)" LTB4R "BLTR, CMKRL1, GPR16, LTB4R1, P2RY7, P2Y7" ENSG00000213903 "Leukotriene B4 receptor" Q15722 14 24311450-24318036 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.2;skin 1: 106.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 61.8;Kupffer cells: 44.5;Suprabasal keratinocytes: 94.9" "Cancer enhanced" "Detected in all" "head and neck cancer: 18.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 100.8" "Group enriched" "Detected in many" 6 "granulocytes: 100.8;monocytes: 38.5" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" HPA003873 Approved NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 12: Squamous epithelial cells - Keratinization" "HPA003873: AB_1078288" "unprognostic (4.07e-2)" "unprognostic (7.67e-2)" "unprognostic (3.67e-3)" "unprognostic (2.40e-3)" "unprognostic (4.90e-2)" "unprognostic (9.00e-3)" "unprognostic (1.15e-2)" "unprognostic (8.63e-2)" "unprognostic (3.68e-1)" "unprognostic (2.06e-1)" "prognostic favorable (1.85e-4)" "unprognostic (7.25e-2)" "prognostic unfavorable (3.44e-15)" "unprognostic (2.88e-1)" "unprognostic (2.97e-1)" "unprognostic (6.59e-2)" "unprognostic (7.45e-2)" LTB4R2 "BLT2, BLTR2, JULF2, NOP9" ENSG00000213906 "Leukotriene B4 receptor 2" Q9NPC1 14 24305734-24312053 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 36.6;skin 1: 44.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 15.6;Basal squamous epithelial cells: 15.7;Squamous epithelial cells: 16.0;Suprabasal keratinocytes: 25.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB022689, HPA029680, HPA072921" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 12: Squamous epithelial cells - Keratinization" "Plasma membrane" Nucleoplasm "CAB022689: , HPA029680: AB_10603013, HPA072921: AB_2686557" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (9.53e-2)" "unprognostic (8.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-1)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.48e-3)" "unprognostic (7.18e-2)" "unprognostic (7.05e-11)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" "unprognostic (1.19e-1)" MAS1 ENSG00000130368 "MAS1 proto-oncogene, G protein-coupled receptor" P04201 6 159890988-159917447 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.1" "Cell type enhanced" "Detected in some" "B-cells: 1.9;Cone photoreceptor cells: 1.7;Langerhans cells: 2.1;Melanocytes: 1.7" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hippocampal formation: 23.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Smooth muscle cells" "Group enriched" "Detected in many" 22 "amygdala: 38.5;basal ganglia: 26.6;cerebral cortex: 32.4;hippocampal formation: 64.6;white matter: 18.1" "Group enriched" "Detected in some" 7 "amygdala: 7.9;cerebral cortex: 12.8;hippocampal formation: 25.7" HPA079325 Uncertain NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 53: Fibroblasts - ECM organization" "HPA079325: " "unprognostic (3.31e-1)" "unprognostic (2.25e-3)" "unprognostic (2.91e-1)" "unprognostic (2.22e-3)" "unprognostic (8.15e-3)" "unprognostic (7.05e-2)" "unprognostic (1.88e-1)" "unprognostic (5.53e-2)" "unprognostic (6.52e-2)" "unprognostic (1.48e-5)" "unprognostic (1.69e-1)" "unprognostic (7.67e-2)" "unprognostic (6.28e-1)" MAS1L "dJ994E9.2, MAS-L, MRG" ENSG00000204687 "MAS1 proto-oncogene like, G protein-coupled receptor" P35410 6 29486697-29487956 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 3.0;epididymis: 1.8" "Cell type enriched" "Detected in single" 18 "granulocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells" HPA017983 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 47: Leukemia - Hemostasis" "Cluster 30: Granulocytes - Unknown function" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017983: AB_1849332" "unprognostic (3.66e-2)" "unprognostic (2.51e-1)" "unprognostic (2.30e-2)" "unprognostic (5.22e-2)" "unprognostic (1.65e-1)" MC1R MSH-R ENSG00000258839 "Melanocortin 1 receptor" Q01726 16 89912119-89920973 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 27.1;testis: 28.2" "Cell type enhanced" "Detected in many" "Horizontal cells: 8.8;Melanocytes: 20.6;Spermatocytes: 10.3" "Cancer enriched" "Detected in many" 5 "melanoma: 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 49.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 78: Testis - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 31: Spermatocytes - Spermatogenesis" 1 "unprognostic (3.90e-2)" "unprognostic (9.05e-2)" "unprognostic (5.39e-7)" "unprognostic (5.00e-2)" "unprognostic (1.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.00e-2)" "unprognostic (1.73e-1)" "unprognostic (1.55e-2)" "unprognostic (8.26e-2)" "prognostic favorable (7.88e-4)" "unprognostic (1.02e-2)" "unprognostic (5.20e-3)" "unprognostic (4.25e-2)" "unprognostic (5.17e-2)" "unprognostic (2.58e-2)" "unprognostic (1.16e-2)" MC2R ACTHR ENSG00000185231 "Melanocortin 2 receptor" Q01718 18 13882044-13915707 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 32 "adrenal gland: 56.1" "Cell type enhanced" "Detected in single" "Late spermatids: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA079148 Enhanced NA NA "Cluster 26: Adrenal gland - Steroid metabolism" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 63: Late spermatids - Spermatogenesis" 2 "HPA079148: " "unprognostic (2.09e-1)" "unprognostic (3.63e-2)" "unprognostic (1.85e-2)" MC3R MC3 ENSG00000124089 "Melanocortin 3 receptor" P41968 20 56248732-56249815 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in many" 10 "hypothalamus: 31.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "basal ganglia: 4.8;hypothalamus: 4.5;thalamus: 1.3" "Group enriched" "Detected in some" 5 "basal ganglia: 4.2;hypothalamus: 2.8;thalamus: 3.3" HPA074739 Uncertain NA NA "Cluster 60: Choroid plexus - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 21: Early spermatids - Spermatogenesis" "HPA074739: " MC4R ENSG00000166603 "Melanocortin 4 receptor" P32245 18 60371062-60372775 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 3.4;fallopian tube: 2.9;retina: 3.8" "Group enriched" "Detected in some" 5 "Bipolar cells: 7.0;Cone photoreceptor cells: 5.1" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Plasma cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.5" HPA016719 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 25: Bipolar cells - Visual perception" "HPA016719: AB_1853617" "unprognostic (2.29e-1)" "unprognostic (5.31e-3)" "unprognostic (5.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (3.33e-1)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-2)" "unprognostic (2.30e-1)" "unprognostic (2.59e-1)" MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.6;lymphoid tissue: 1.0" "Group enriched" "Detected in some" 4 "Late spermatids: 6.5;Squamous epithelial cells: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Sebaceous gland cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 11: Late spermatids - Unknown function" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" MCHR1 "GPR24, MCH1R, SLC1" ENSG00000128285 "Melanin concentrating hormone receptor 1" Q99705 22 40679273-40682812 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.8;ovary: 10.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 3.6;Inhibitory neurons: 4.2;Leydig cells: 3.4;Melanocytes: 10.3;Microglial cells: 2.7;Ovarian stromal cells: 6.7;Pancreatic endocrine cells: 3.4" "Group enriched" "Detected in some" 7 "glioma: 4.9;liver cancer: 1.5;melanoma: 3.1;renal cancer: 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Rhabdoid: 27.6" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 33.3" NA NA "Cluster 64: Neuronal - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" "unprognostic (3.37e-2)" "unprognostic (1.37e-2)" "unprognostic (2.45e-3)" "unprognostic (2.68e-1)" "unprognostic (2.84e-3)" "unprognostic (4.92e-3)" "unprognostic (4.51e-3)" "unprognostic (1.19e-2)" "unprognostic (1.58e-2)" "unprognostic (9.35e-4)" "unprognostic (3.05e-1)" "unprognostic (2.26e-1)" "prognostic unfavorable (1.49e-6)" "unprognostic (3.07e-2)" "unprognostic (5.40e-2)" "unprognostic (2.42e-1)" "unprognostic (3.91e-2)" MCHR2 "GPR145, MCH2, MCH2R, SLT" ENSG00000152034 "Melanin concentrating hormone receptor 2" Q969V1 6 99918519-99994247 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 5.1;testis: 1.5" "Cell type enriched" "Detected in some" 29 "Excitatory neurons: 42.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" NA NA "Cluster 5: Brain & Testis - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (5.76e-2)" MLNR GPR38 ENSG00000102539 "Motilin receptor" O43193 13 49220338-49222377 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;thyroid gland: 1.6" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070324 Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA070324: " "unprognostic (9.75e-2)" "unprognostic (2.13e-2)" "unprognostic (2.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.03e-2)" "unprognostic (7.80e-2)" "unprognostic (1.54e-2)" "unprognostic (7.79e-2)" "unprognostic (1.88e-2)" "unprognostic (3.74e-1)" "unprognostic (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.38e-1)" MRGPRD mrgD ENSG00000172938 "MAS related GPR family member D" Q8TDS7 11 68980021-68980986 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031346 Uncertain NA NA "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "HPA031346: AB_10602710" "unprognostic (1.92e-1)" "unprognostic (7.14e-2)" "unprognostic (1.72e-1)" MRGPRE "GPR167, mrgE" ENSG00000184350 "MAS related GPR family member E" Q86SM8 11 3225030-3232417 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Erythroid cells: 1.1;Horizontal cells: 2.5" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 0.9" "Region enhanced" "Detected in many" "pons: 58.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046556 Uncertain NA NA "Cluster 49: Hindbrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "HPA046556: AB_10961404" "unprognostic (1.18e-1)" "unprognostic (7.52e-4)" "unprognostic (1.04e-1)" "unprognostic (9.09e-2)" "unprognostic (6.65e-2)" "unprognostic (1.77e-2)" "unprognostic (1.27e-1)" "unprognostic (1.83e-1)" "unprognostic (2.22e-2)" "unprognostic (1.19e-1)" MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 165.4;intestine: 153.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 30.0;Leydig cells: 66.2;Mesothelial cells: 31.1;Ovarian stromal cells: 29.9;Peritubular cells: 97.6;Smooth muscle cells: 96.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 21.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 7.4" "Breast - Smooth muscle cells, Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid - Smooth muscle cells" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in many" "spinal cord: 6.4" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" MRGPRG "GPR169, mrgG" ENSG00000182170 "MAS related GPR family member G" Q86SM5 11 3217944-3218813 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "breast cancer: 2.1" "Not detected" "Not detected" HPA058909 Uncertain NA NA "Cluster 70: DU4475 - Unknown function" "HPA058909: AB_2683852" MRGPRX1 MRGX1 ENSG00000170255 "MAS related GPR family member X1" Q96LB2 11 18933499-18939414 "G-protein coupled receptors, Predicted membrane proteins" "Acute phase" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 15 "Rhabdoid: 39.4" NA NA "Cluster 3: Rhabdoid - Membrane components" MRGPRX2 MRGX2 ENSG00000183695 "MAS related GPR family member X2" Q96LB1 11 19054455-19060717 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skin 1: 1.0" "Group enriched" "Detected in some" 5 "granulocytes: 6.7;Melanocytes: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Mast cells, Colon - Mast cells, Skin - Mast cells" HPA055220 Approved NA NA "Cluster 13: Skin - Cornification" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Granulocytes - Unknown function" "HPA055220: AB_2682743" "unprognostic (1.56e-2)" "unprognostic (1.79e-1)" MRGPRX3 MRGX3 ENSG00000179826 "MAS related GPR family member X3" Q96LB0 11 18120955-18138488 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "salivary gland: 2.6" "Cell type enriched" "Detected in some" 18 "Basal respiratory cells: 48.1" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.3;melanoma: 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 11.9" NA NA "Cluster 38: Salivary gland - Salivary secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Respiratory epithelial cells - Unknown function" 1 "unprognostic (1.54e-3)" "unprognostic (5.07e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (7.65e-2)" "unprognostic (1.74e-1)" "unprognostic (4.75e-2)" "unprognostic (2.09e-1)" MRGPRX4 MRGX4 ENSG00000179817 "MAS related GPR family member X4" Q96LA9 11 18172837-18174280 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "melanoma: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "skin cancer: 2.7" NA NA "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Respiratory epithelial cells - Unknown function" "unprognostic (2.10e-2)" MTNR1A MEL-1A-R ENSG00000168412 "Melatonin receptor 1A" P48039 4 186526792-186555567 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "kidney: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.2" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 56: Proximal tubular cells - Amino acid metabolism" 7 "unprognostic (7.99e-2)" "unprognostic (2.27e-1)" "unprognostic (2.16e-1)" "unprognostic (3.67e-1)" "unprognostic (2.14e-1)" "unprognostic (9.88e-2)" "unprognostic (9.20e-2)" "unprognostic (8.81e-2)" MTNR1B ENSG00000134640 "Melatonin receptor 1B" P49286 11 92969651-92985066 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "placenta: 1.0" "Cell type enhanced" "Detected in single" "Granulosa cells: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 3.8;testis cancer: 1.2" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA074024 Supported NA NA "Cluster 34: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 27: Syncytiotrophoblasts - Pregnancy" 4 "HPA074024: " "unprognostic (3.61e-1)" "unprognostic (1.43e-1)" NMBR "BB1, BB1R, BRS1" ENSG00000135577 "Neuromedin B receptor" P28336 6 142058330-142147122 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Astrocytes: 3.1;Early spermatids: 8.9;Excitatory neurons: 2.3;Inhibitory neurons: 4.3;Oligodendrocyte precursor cells: 1.9;Oligodendrocytes: 2.4;Spermatocytes: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026665 Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "Cluster 69: Neurons - Neuronal signaling" "Plasma membrane, Cytosol" "HPA026665: AB_1854527" "unprognostic (6.24e-2)" "unprognostic (3.05e-1)" "unprognostic (2.77e-2)" "unprognostic (7.88e-2)" "unprognostic (3.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.63e-2)" "unprognostic (1.54e-1)" "unprognostic (3.95e-1)" "unprognostic (7.94e-3)" "unprognostic (3.44e-1)" "unprognostic (2.11e-1)" "unprognostic (8.45e-2)" NMUR1 "FM-3, GPC-R, GPR66, NMU1R" ENSG00000171596 "Neuromedin U receptor 1" Q9HB89 2 231523187-231530445 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "retina: 7.9" "Cell type enhanced" "Detected in some" "NK-cells: 32.1;Peritubular cells: 7.6;Rod photoreceptor cells: 17.5;T-cells: 6.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 18.0;MAIT T-cell: 4.5;memory CD8 T-cell: 8.7;naive CD8 T-cell: 5.1;NK-cell: 10.9" "Group enriched" "Detected in many" 23 "NK-cells: 10.9;T-cells: 18.0" "Cancer enhanced" "Detected in single" "Leukemia: 1.7" "Stomach - Fibroblasts, Thyroid - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA027895 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 39: Retina & Testis - Cilium" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA027895: AB_10602713" "unprognostic (1.11e-2)" "unprognostic (1.14e-2)" "unprognostic (6.74e-3)" "unprognostic (9.44e-3)" "unprognostic (2.67e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (3.13e-2)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" "unprognostic (1.22e-2)" "unprognostic (2.07e-1)" "unprognostic (4.08e-4)" "unprognostic (3.76e-3)" "unprognostic (2.26e-1)" "unprognostic (2.61e-1)" "unprognostic (5.25e-2)" NMUR2 NMU2R ENSG00000132911 "Neuromedin U receptor 2" Q9GZQ4 5 152391546-152433368 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "stomach 1: 1.0;testis: 1.5" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 3.5;Oligodendrocytes: 7.9;Sertoli cells: 2.7" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;stomach cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.5;pancreatic cancer: 8.1" "Testis - Sertoli cells" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" "HPA027800, HPA045836" Enhanced Supported "Plasma membrane" NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Oligodendrocytes - Unknown function" 3 "Plasma membrane" "HPA027800: , HPA045836: AB_10968856" "unprognostic (1.82e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-1)" "unprognostic (9.29e-2)" "unprognostic (5.87e-2)" "unprognostic (6.44e-3)" "unprognostic (3.13e-1)" "unprognostic (6.47e-2)" "unprognostic (5.63e-2)" "unprognostic (8.20e-3)" "unprognostic (8.90e-5)" "unprognostic (1.48e-2)" "unprognostic (9.24e-2)" "unprognostic (9.56e-2)" "unprognostic (2.29e-1)" NPBWR1 GPR7 ENSG00000288611 "Neuropeptides B and W receptor 1" P48145 8 52939182-52943734 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;liver: 2.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.9;Hepatocytes: 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 11.0" NA NA "Cluster 14: Neurons - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 62: Hepatocytes - Metabolism" 1 NPBWR2 GPR8 ENSG00000125522 "Neuropeptides B and W receptor 2" P48146 20 64103802-64107565 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "cerebral cortex: 5.8;white matter: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in single" "olfactory bulb: 1.1" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 73: B-cells - B-cell function" 15 "unprognostic (1.44e-1)" NPFFR1 "GPR147, NPFF1R1, OT7T022" ENSG00000148734 "Neuropeptide FF receptor 1" Q9GZQ6 10 70247329-70284004 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.8;retina: 3.0" "Cell type enhanced" "Detected in some" "Astrocytes: 6.2;Granulosa cells: 3.5;Muller glia cells: 8.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Testis - Sertoli cells" "Group enriched" "Detected in many" 5 "basal ganglia: 15.7;hypothalamus: 6.3" "Low region specificity" "Detected in some" HPA037521 Uncertain NA NA "Cluster 28: Neuronal - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 10: Muller glia cells - Visual perception" 2 "HPA037521: AB_2675520" "unprognostic (1.73e-3)" "unprognostic (7.29e-4)" "unprognostic (2.12e-1)" "unprognostic (3.50e-2)" "unprognostic (2.07e-1)" "unprognostic (8.66e-3)" "unprognostic (1.37e-1)" "unprognostic (1.48e-1)" "unprognostic (4.14e-2)" "unprognostic (3.51e-1)" "unprognostic (9.62e-2)" "unprognostic (6.78e-2)" "unprognostic (5.84e-5)" "unprognostic (1.37e-1)" "unprognostic (3.93e-2)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" NPFFR2 "GPR74, NPFF2, NPGPR" ENSG00000056291 "Neuropeptide FF receptor 2" Q9Y5X5 4 72031902-72148305 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.0;seminal vesicle: 3.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 21.8;Cytotrophoblasts: 6.8;Excitatory neurons: 13.9;Extravillous trophoblasts: 13.7;Oocytes: 8.8;Syncytiotrophoblasts: 10.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 14.7" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.3" "Low region specificity" "Detected in all" HPA026825 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 71: Thymus - Adaptive immune response" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Breast glandular cells - Lactation" "Plasma membrane" "Actin filaments" "HPA026825: AB_10603123" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (6.07e-2)" "unprognostic (4.68e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.51e-1)" "unprognostic (2.40e-5)" "unprognostic (5.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" NPSR1 "GPR154, GPRA, PGR14" ENSG00000187258 "Neuropeptide S receptor 1" Q6W5P4 7 34658218-34878332 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 3.0;Excitatory neurons: 3.6;Inhibitory neurons: 2.1;Late spermatids: 3.8" "Group enriched" "Detected in some" 5 "colorectal cancer: 2.3;pancreatic cancer: 2.0;stomach cancer: 2.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Bile duct cancer: 5.5;colorectal cancer: 7.6;Gastric cancer: 9.9;pancreatic cancer: 2.7" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (3.56e-1)" "unprognostic (9.34e-2)" "unprognostic (7.55e-2)" "unprognostic (1.80e-1)" "unprognostic (2.00e-2)" "unprognostic (9.35e-2)" "unprognostic (6.34e-3)" "unprognostic (2.85e-1)" "unprognostic (1.36e-2)" "unprognostic (2.08e-2)" NPY1R NPYR ENSG00000164128 "Neuropeptide Y receptor Y1" P25929 4 163323962-163344832 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 116.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 38.4;Fibroblasts: 25.1;Inhibitory neurons: 18.0;Paneth cells: 21.5;Smooth muscle cells: 36.4" "Cancer enriched" "Detected in many" 13 "breast cancer: 65.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 8 "Bone cancer: 57.1;breast cancer: 33.5" "Kidney - Fibroblasts, Skeletal muscle - Smooth muscle cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 47: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "prognostic favorable (7.68e-5)" "unprognostic (9.14e-3)" "unprognostic (1.55e-1)" "unprognostic (5.09e-2)" "unprognostic (2.60e-1)" "unprognostic (9.29e-2)" "unprognostic (5.28e-3)" "unprognostic (2.26e-1)" "unprognostic (4.14e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (5.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.92e-3)" "unprognostic (5.48e-2)" "unprognostic (1.74e-1)" "unprognostic (2.21e-1)" NPY2R ENSG00000185149 "Neuropeptide Y receptor Y2" P49146 4 155208636-155217078 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;breast: 1.5" "Cell type enhanced" "Detected in some" "Breast glandular cells: 3.2;Excitatory neurons: 6.5;Granulosa cells: 7.5;Leydig cells: 21.3;Oligodendrocytes: 12.8" "Cancer enhanced" "Detected in single" "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 14 "Neuroblastoma: 4.5" "Colon - Colon enteroendocrine cells" "Group enriched" "Detected in many" 5 "amygdala: 12.9;basal ganglia: 12.3;hippocampal formation: 46.8;hypothalamus: 23.7" "Region enriched" "Detected in all" 5 "hippocampal formation: 19.3" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 51: Oligodendrocytes - Unknown function" "unprognostic (7.14e-2)" "unprognostic (4.36e-3)" "unprognostic (7.08e-2)" "unprognostic (5.50e-2)" "unprognostic (9.35e-2)" NPY4R "PP1, PPYR1, Y4" ENSG00000204174 "Neuropeptide Y receptor Y4" P50391 10 46461099-46465958 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 5.8;skin 1: 2.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Bile duct cancer: 10.5" "Prostate - Prostate glandular cells" HPA027863 Approved NA NA "Cluster 45: Intestine - Digestion" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "HPA027863: AB_10602819" "unprognostic (2.26e-6)" "unprognostic (2.94e-1)" "unprognostic (8.17e-2)" "unprognostic (1.20e-1)" "unprognostic (1.30e-1)" "unprognostic (1.77e-3)" "unprognostic (1.98e-1)" "unprognostic (2.64e-3)" "unprognostic (6.58e-2)" "unprognostic (9.79e-2)" NPY5R NPYR5 ENSG00000164129 "Neuropeptide Y receptor Y5" Q15761 4 163343892-163351934 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.9;lymphoid tissue: 8.6" "Cell type enhanced" "Detected in some" "Excitatory neurons: 4.5;Fibroblasts: 1.2;Inhibitory neurons: 3.3;Paneth cells: 1.2;Smooth muscle cells: 2.8;Spermatocytes: 2.5" "Cancer enhanced" "Detected in single" "breast cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 6.8" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 47: Spleen - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 69: Neurons - Neuronal signaling" "unprognostic (4.63e-6)" "unprognostic (3.00e-1)" "unprognostic (2.79e-1)" "unprognostic (2.13e-1)" "unprognostic (1.24e-1)" "unprognostic (3.74e-2)" "unprognostic (3.94e-2)" "unprognostic (5.40e-2)" "unprognostic (4.30e-2)" "unprognostic (3.99e-2)" "unprognostic (1.76e-1)" "unprognostic (3.94e-1)" NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708836-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 10.8" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.3;Excitatory neurons: 1.5;Inhibitory neurons: 1.2;Kupffer cells: 3.4;Undifferentiated cells: 1.6" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.9" "Region enriched" "Detected in many" 6 "midbrain: 25.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.8;Gastric cancer: 13.5;pancreatic cancer: 19.5" "Kidney - Ascending Loop of Henle cells, Lung - Neutrophil_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA050299 Supported "Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Bipolar cells - Visual perception" 1 "Plasma membrane" "HPA050299: " "unprognostic (4.14e-2)" "unprognostic (2.02e-2)" "unprognostic (2.75e-2)" "unprognostic (8.87e-4)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.17e-2)" "unprognostic (2.80e-3)" "unprognostic (7.16e-2)" "unprognostic (3.10e-3)" "unprognostic (3.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" NTSR2 NTR2 ENSG00000169006 "Neurotensin receptor 2" O95665 2 11658178-11670195 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 50 "brain: 111.2" "Cell type enriched" "Detected in some" 15 "Astrocytes: 31.0" "Cancer enriched" "Detected in single" 15 "glioma: 6.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 47: Astrocytes - Unknown function" "unprognostic (5.40e-2)" "unprognostic (2.30e-2)" "unprognostic (2.36e-2)" "unprognostic (5.32e-2)" "unprognostic (2.23e-1)" "unprognostic (1.80e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-1)" "unprognostic (1.64e-1)" OPN1LW "CBBM, CBP, COD5, RCP" ENSG00000102076 "Opsin 1, long wave sensitive" P04000 X 154144243-154159032 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 2483 "retina: 248.2" "Cell type enriched" "Detected in some" 25 "Cone photoreceptor cells: 1954.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 76: Retina - Visual perception" "Cluster 66: Photoreceptor cells - Visual perception" 1 "unprognostic (6.05e-2)" OPN1MW "CBBM, CBD, COD5, GCP, OPN1MW1" ENSG00000268221 "Opsin 1, medium wave sensitive" P04001 X 154182596-154196861 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 94 "retina: 13.1" "Cell type enriched" "Detected in some" 51 "Cone photoreceptor cells: 108.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 76: Retina - Visual perception" "Cluster 72: Neuronal - Signal transduction" "Cluster 66: Photoreceptor cells - Visual perception" OPN1SW "BCP, BOP, CBT" ENSG00000128617 "Opsin 1, short wave sensitive" P03999 7 128772485-128775794 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 84 "retina: 39.7" "Cell type enriched" "Detected in some" 20 "Cone photoreceptor cells: 85.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Endothelial cells, Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA013562, HPA014083" Enhanced Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 76: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 66: Photoreceptor cells - Visual perception" "Nucleoplasm, Cytosol" "Cytokinetic bridge" "HPA013562: AB_2668850, HPA014083: AB_2668938" "unprognostic (2.88e-1)" "unprognostic (5.17e-2)" "unprognostic (2.22e-2)" "unprognostic (1.33e-2)" "unprognostic (2.55e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (8.50e-5)" "unprognostic (1.13e-1)" "unprognostic (1.27e-1)" "unprognostic (6.33e-2)" "unprognostic (3.79e-1)" "unprognostic (6.05e-2)" "prognostic unfavorable (2.26e-8)" "prognostic unfavorable (5.98e-8)" "unprognostic (2.53e-1)" "unprognostic (8.99e-2)" "prognostic unfavorable (9.33e-4)" OPN3 "ECPN, encephalopsin, ERO, NMO-1, PPP1R116" ENSG00000054277 "Opsin 3" Q9H1Y3 1 241590102-241677376 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 18.1" "Cell type enhanced" "Detected in many" "dendritic cells: 210.0;Early spermatids: 161.5;Extravillous trophoblasts: 280.4;Langerhans cells: 251.8;Late spermatids: 106.7;Syncytiotrophoblasts: 155.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 10.0" "Lineage enriched" "Detected in many" 5 "dendritic cells: 10.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "CAB013682, HPA064443" Uncertain Approved Nucleoplasm NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 11: Liver - Plasma proteins" "Cluster 53: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Dendritic cells - Antigen presentation" 1 Nucleoplasm "CAB013682: , HPA064443: AB_2685267" "unprognostic (2.41e-2)" "prognostic unfavorable (3.17e-5)" "unprognostic (1.75e-2)" "unprognostic (1.93e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (7.12e-2)" "unprognostic (5.10e-3)" "unprognostic (1.24e-2)" "unprognostic (2.39e-1)" "unprognostic (4.96e-1)" "unprognostic (2.66e-2)" "unprognostic (3.44e-1)" "unprognostic (9.13e-2)" "unprognostic (9.15e-3)" "unprognostic (2.61e-2)" "unprognostic (7.12e-2)" "unprognostic (9.44e-3)" OPN4 "melanopsin, MOP" ENSG00000122375 "Opsin 4" Q9UHM6 10 86654518-86666460 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Biological rhythms, Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.9;brain: 2.8;skeletal muscle: 2.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.7;Horizontal cells: 1.3;Inhibitory neurons: 1.8;Smooth muscle cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA039147 Approved NA NA "Cluster 54: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 1 "HPA039147: AB_10673304" "unprognostic (3.67e-3)" "unprognostic (1.40e-2)" "unprognostic (3.02e-2)" "unprognostic (1.62e-1)" "unprognostic (7.03e-3)" "unprognostic (2.89e-2)" "unprognostic (3.26e-1)" "unprognostic (9.54e-2)" "unprognostic (5.68e-2)" "unprognostic (8.88e-3)" "unprognostic (1.93e-6)" "unprognostic (4.10e-2)" "unprognostic (5.58e-2)" "unprognostic (6.76e-2)" OPN5 "dJ402H5.1, neuropsin, TMEM13" ENSG00000124818 "Opsin 5" Q6U736 6 47781982-47832780 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 2.5" "Group enriched" "Detected in some" 12 "Early spermatids: 31.3;Late spermatids: 25.6;Spermatocytes: 10.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA026084 Supported NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 66: Non-specific - Mitochondria" "Cluster 36: Late spermatids - Unknown function" "HPA026084: AB_2671807" "unprognostic (1.95e-1)" "unprognostic (6.18e-2)" "unprognostic (4.84e-1)" "unprognostic (1.07e-1)" OPRD1 ENSG00000116329 "Opioid receptor delta 1" P41143 1 28812170-28871267 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 11.4;Inhibitory neurons: 15.2" "Cancer enhanced" "Detected in single" "melanoma: 1.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 7.1;skin cancer: 4.4" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pancreas - Beta cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070831 Approved NA NA "Cluster 33: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 8: Neurons - Neuronal signaling" 7 "HPA070831: AB_2732167" "unprognostic (1.44e-1)" "unprognostic (4.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.89e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-3)" "unprognostic (6.28e-3)" "unprognostic (5.92e-2)" "unprognostic (1.82e-2)" "unprognostic (5.95e-3)" "unprognostic (4.28e-3)" "unprognostic (2.98e-1)" "unprognostic (1.52e-7)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (2.18e-3)" OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;prostate: 1.6;skeletal muscle: 1.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 6.4;Extravillous trophoblasts: 9.2;Glandular and luminal cells: 8.6;Inhibitory neurons: 9.7;Leydig cells: 5.1;Prostatic glandular cells: 18.3" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.1;prostate cancer: 3.8" "Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Glandular & Luminal cells - Unknown function" 3 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: AB_2732770" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" OPRL1 "KOR-3, NOCIR, NOPr, OOR, ORL1, PNOCR" ENSG00000125510 "Opioid related nociceptin receptor 1" P41146 20 64080082-64100643 "G-protein coupled receptors, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.8;lymphoid tissue: 4.4;testis: 6.5" "Cell type enhanced" "Detected in some" "Early spermatids: 12.2;Excitatory neurons: 6.0;Late spermatids: 31.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 3.9;eosinophil: 5.8;intermediate monocyte: 5.5;myeloid DC: 4.7;neutrophil: 4.9;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 11 "dendritic cells: 4.7;granulocytes: 5.8;monocytes: 12.5" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 5: Brain & Testis - Signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 36: Late spermatids - Unknown function" 1 "unprognostic (9.03e-3)" "unprognostic (4.78e-2)" "unprognostic (4.35e-3)" "unprognostic (3.74e-1)" "unprognostic (4.13e-2)" "unprognostic (9.63e-2)" "unprognostic (2.13e-4)" "unprognostic (1.53e-1)" "unprognostic (1.67e-1)" "unprognostic (2.91e-1)" "unprognostic (2.66e-4)" "unprognostic (1.47e-1)" "unprognostic (1.12e-4)" "unprognostic (1.99e-2)" "unprognostic (4.17e-2)" "unprognostic (1.93e-1)" "unprognostic (4.01e-3)" OPRM1 "MOP, MOR1" ENSG00000112038 "Opioid receptor mu 1" P35372 6 154010496-154246867 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;testis: 2.8" "Cell type enhanced" "Detected in some" "Early spermatids: 36.1;Excitatory neurons: 39.8;Inhibitory neurons: 22.4;Late spermatids: 34.8;Microglial cells: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in single" 7 "Neuroblastoma: 4.3" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014509, HPA067435" Enhanced Supported NA NA "Cluster 78: Testis - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 34: Neurons - Neuronal signaling" 13 "HPA014509: AB_1854801, HPA067435: " "unprognostic (7.34e-2)" "unprognostic (6.91e-2)" OXER1 "GPCR, GPR170, TG1019" ENSG00000162881 "Oxoeicosanoid receptor 1" Q8TDS5 2 42762499-42764135 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 55.0" "Cell type enhanced" "Detected in some" "Hepatocytes: 6.4;Melanocytes: 5.2;Paneth cells: 5.2;Proximal enterocytes: 13.9" "Cancer enhanced" "Detected in all" "liver cancer: 12.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 73.5;eosinophil: 158.2" "Lineage enriched" "Detected in many" 81 "granulocytes: 158.2" "Cancer enhanced" "Detected in some" "liver cancer: 2.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts" HPA051433 Approved NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 83: Liver - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 22: Proximal enterocytes - Digestion" 29 "HPA051433: AB_2681485" "unprognostic (6.77e-2)" "unprognostic (4.20e-2)" "unprognostic (3.13e-2)" "unprognostic (1.07e-1)" "unprognostic (4.09e-3)" "unprognostic (4.45e-3)" "unprognostic (7.80e-2)" "unprognostic (4.40e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (3.42e-3)" "unprognostic (5.39e-2)" "unprognostic (1.82e-3)" "unprognostic (5.83e-2)" "unprognostic (1.66e-1)" "unprognostic (4.89e-2)" "unprognostic (5.46e-2)" OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985713-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.9;Rhabdoid: 5.3" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Pancreas - Beta cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 4: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" OXTR OTR ENSG00000180914 "Oxytocin receptor" P30559 3 8750381-8769628 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "breast: 52.4" "Cell type enriched" "Detected in many" 6 "Breast myoepithelial cells: 158.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 73: Breast - Lactation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Neurons - Neuronal signaling" "unprognostic (1.18e-1)" "unprognostic (7.94e-2)" "unprognostic (4.76e-2)" "unprognostic (1.29e-2)" "unprognostic (2.02e-2)" "unprognostic (2.02e-1)" "unprognostic (1.46e-2)" "unprognostic (2.56e-3)" "unprognostic (2.12e-1)" "unprognostic (3.42e-1)" "unprognostic (2.76e-1)" "unprognostic (3.80e-2)" "unprognostic (4.24e-4)" "unprognostic (8.25e-2)" "unprognostic (4.60e-2)" "unprognostic (2.71e-1)" "unprognostic (1.84e-1)" P2RY1 "P2Y1, SARCC" ENSG00000169860 "Purinergic receptor P2Y1" P47900 3 152835131-152841439 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 24.6" "Cell type enhanced" "Detected in many" "monocytes: 91.9;Prostatic glandular cells: 61.5;Squamous epithelial cells: 45.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 6.0;non-classical monocyte: 2.7" "Group enriched" "Detected in many" 9 "granulocytes: 6.0;monocytes: 2.7" "Cancer enhanced" "Detected in many" "cervical cancer: 9.6;Gallbladder cancer: 11.3" "Adipose subcutaneous - Macrophages, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015577 Enhanced NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 75: Epithelium - Extracellular exosomes" "Cluster 33: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 57: Platelets - Hemostasis" 1 "HPA015577: AB_1854882" "unprognostic (3.30e-1)" "unprognostic (4.52e-2)" "unprognostic (2.68e-2)" "unprognostic (4.76e-2)" "unprognostic (9.70e-2)" "unprognostic (1.40e-3)" "unprognostic (3.32e-2)" "unprognostic (2.53e-1)" "unprognostic (5.14e-1)" "unprognostic (2.58e-1)" "unprognostic (4.68e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (2.04e-7)" "unprognostic (1.36e-1)" "unprognostic (8.98e-2)" "unprognostic (7.33e-2)" "unprognostic (3.20e-2)" P2RY10 P2Y10 ENSG00000078589 "P2Y receptor family member 10" O00398 X 78945332-78963727 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 26.8" "Cell type enhanced" "Detected in some" "B-cells: 110.4;Langerhans cells: 73.3;NK-cells: 27.0;Plasma cells: 37.8;Schwann cells: 37.7;T-cells: 89.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 256.9" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Leukemia: 4.9;lymphoma: 14.7;Myeloma: 17.4" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Thyroid - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA036757, HPA065766" Enhanced NA NA "Cluster 32: Basophils - Transcription" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 55: Lymphoma - Immune response" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA036757: AB_10696786, HPA065766: AB_2685556" "unprognostic (3.02e-3)" "unprognostic (1.47e-3)" "unprognostic (1.50e-6)" "unprognostic (6.62e-3)" "unprognostic (1.19e-1)" "unprognostic (1.13e-4)" "unprognostic (3.33e-2)" "unprognostic (8.30e-2)" "unprognostic (1.13e-2)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (8.66e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (2.23e-1)" "unprognostic (6.54e-2)" "unprognostic (3.85e-2)" "unprognostic (3.99e-2)" P2RY11 P2Y11 ENSG00000244165 "Purinergic receptor P2Y11" Q96G91 19 10111693-10115372 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 33.1;NK-cells: 13.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.9" "Group enriched" "Detected in many" 5 "NK-cells: 13.9;T-cells: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014232 Approved NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 19: NK-cells - Adaptive immune response" "HPA014232: AB_1854883" "unprognostic (1.13e-1)" "unprognostic (3.12e-2)" "unprognostic (2.76e-3)" "unprognostic (2.61e-3)" "unprognostic (1.82e-1)" "unprognostic (2.79e-2)" "unprognostic (2.34e-1)" "unprognostic (5.56e-2)" "unprognostic (2.23e-1)" "unprognostic (1.93e-1)" "unprognostic (2.04e-3)" "unprognostic (2.22e-2)" "unprognostic (4.32e-3)" "unprognostic (1.76e-2)" "unprognostic (3.78e-2)" "unprognostic (1.58e-1)" "prognostic favorable (1.77e-4)" P2RY12 "HORK3, P2Y12, SP1999" ENSG00000169313 "Purinergic receptor P2Y12" Q9H244 3 151336843-151384753 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 43.4" "Cell type enriched" "Detected in some" 12 "Microglial cells: 402.6" "Cancer enriched" "Detected in many" 14 "glioma: 17.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 8.3" "Group enriched" "Detected in many" 11 "dendritic cells: 3.2;monocytes: 8.3" "Cancer enhanced" "Detected in single" "head and neck cancer: 3.0" "Pancreas - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013796, HPA014518" Enhanced NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 33: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 65: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA013796: AB_1854884, HPA014518: AB_2669027" "unprognostic (2.39e-2)" "unprognostic (1.60e-3)" "unprognostic (5.93e-2)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" "unprognostic (2.52e-2)" "unprognostic (8.09e-2)" "unprognostic (1.72e-3)" "unprognostic (6.46e-2)" "unprognostic (8.64e-4)" "unprognostic (4.84e-2)" "unprognostic (5.96e-2)" "unprognostic (2.03e-1)" "unprognostic (8.92e-2)" "unprognostic (1.65e-1)" "unprognostic (3.52e-2)" "unprognostic (4.04e-1)" P2RY13 "FKSG77, GPR86, GPR94, P2Y13" ENSG00000181631 "Purinergic receptor P2Y13" Q9BPV8 3 151326312-151329549 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.8;lymphoid tissue: 35.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 23.8;Kupffer cells: 95.4;Macrophages: 56.3;Microglial cells: 63.5;monocytes: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 583.2" "Group enriched" "Detected in many" 6 "granulocytes: 583.2;monocytes: 186.3" "Not detected" "Not detected" "Kidney - Macrophages, Liver - Kupffer cells, Stomach - Macrophages, Testis - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049047 Enhanced NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 1 "HPA049047: AB_2680611" "unprognostic (1.09e-3)" "unprognostic (7.51e-4)" "unprognostic (1.68e-2)" "unprognostic (2.37e-3)" "unprognostic (3.95e-2)" "unprognostic (8.66e-3)" "unprognostic (7.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.84e-3)" "unprognostic (1.83e-1)" "unprognostic (4.97e-2)" "unprognostic (1.17e-1)" "unprognostic (4.05e-1)" "unprognostic (4.46e-1)" "unprognostic (5.95e-2)" "unprognostic (2.21e-3)" "unprognostic (3.78e-1)" P2RY14 "GPR105, KIAA0001" ENSG00000174944 "Purinergic receptor P2Y14" Q15391 3 151212117-151278542 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 30.6" "Cell type enhanced" "Detected in some" "dendritic cells: 205.0;Endometrial stromal cells: 46.1;Excitatory neurons: 39.9;granulocytes: 44.3;Langerhans cells: 71.3;Schwann cells: 43.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 57.6" "Group enriched" "Detected in many" 9 "eosinophil: 230.9;plasmacytoid DC: 98.2" "Group enriched" "Detected in many" 9 "dendritic cells: 98.2;granulocytes: 230.9" "Cancer enhanced" "Detected in some" "Leukemia: 1.6;Rhabdoid: 2.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022646 Uncertain NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 58: Placenta - Pregnancy" "Cluster 23: Choroid plexus - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 28: Dendritic cells - Antigen presentation" "CAB022646: " "unprognostic (9.78e-2)" "unprognostic (7.47e-4)" "unprognostic (3.89e-2)" "unprognostic (4.52e-4)" "unprognostic (1.69e-2)" "unprognostic (2.57e-5)" "unprognostic (2.68e-2)" "unprognostic (1.55e-2)" "unprognostic (2.65e-1)" "unprognostic (1.64e-3)" "unprognostic (6.30e-2)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.72e-5)" "unprognostic (3.79e-2)" "unprognostic (6.89e-2)" "unprognostic (1.58e-1)" "unprognostic (2.58e-2)" P2RY2 P2U ENSG00000175591 "Purinergic receptor P2Y2" P41231 11 73218281-73242427 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 28.9;skeletal muscle: 48.4;tongue: 29.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.3;Proximal enterocytes: 15.0;Squamous epithelial cells: 15.4;Suprabasal keratinocytes: 13.7;Syncytiotrophoblasts: 14.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 57.7" "Group enriched" "Detected in many" 12 "granulocytes: 57.7;monocytes: 20.2" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" CAB022642 Uncertain Uncertain Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Monocytes - Innate immune response" 1 Cytosol "CAB022642: " "unprognostic (1.24e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-2)" "unprognostic (7.97e-3)" "unprognostic (6.50e-4)" "unprognostic (2.04e-2)" "unprognostic (4.66e-3)" "unprognostic (8.93e-2)" "unprognostic (2.87e-1)" "unprognostic (4.17e-2)" "prognostic unfavorable (2.19e-5)" "unprognostic (9.69e-2)" "unprognostic (4.92e-4)" "unprognostic (1.34e-1)" "unprognostic (2.82e-1)" "unprognostic (1.05e-1)" "unprognostic (8.57e-3)" P2RY4 "NRU, P2P, P2Y4, UNR" ENSG00000186912 "Pyrimidinergic receptor P2Y4" P51582 X 70258166-70260204 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 2.1" "Cell type enriched" "Detected in single" 8 "Intestinal goblet cells: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB022644 Uncertain NA NA "Cluster 45: Intestine - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 16: Intestinal goblet cells - Mucin production" 1 "CAB022644: " "unprognostic (4.59e-2)" "unprognostic (4.23e-1)" "unprognostic (7.10e-2)" "unprognostic (1.69e-1)" "unprognostic (9.53e-4)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (6.77e-2)" "unprognostic (2.43e-1)" "unprognostic (2.09e-1)" "unprognostic (8.89e-3)" "unprognostic (2.90e-2)" "unprognostic (3.72e-2)" "unprognostic (3.61e-2)" "unprognostic (1.50e-2)" "unprognostic (3.89e-1)" P2RY6 P2Y6 ENSG00000171631 "Pyrimidinergic receptor P2Y6" Q15077 11 73264498-73305103 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 31.7" "Group enriched" "Detected in many" 12 "Cytotrophoblasts: 163.4;dendritic cells: 509.0;Syncytiotrophoblasts: 371.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "myeloid DC: 27.2;plasmacytoid DC: 87.6" "Lineage enriched" "Detected in many" 19 "dendritic cells: 87.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074751 Enhanced NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Dendritic cells - Antigen presentation" 15 "HPA074751: " "unprognostic (2.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.04e-2)" "unprognostic (5.54e-3)" "unprognostic (4.18e-3)" "unprognostic (1.94e-2)" "unprognostic (3.93e-3)" "unprognostic (4.00e-3)" "unprognostic (1.86e-4)" "unprognostic (3.08e-1)" "unprognostic (1.25e-2)" "unprognostic (2.18e-1)" "prognostic unfavorable (2.50e-7)" "unprognostic (1.48e-2)" "unprognostic (1.38e-3)" "unprognostic (7.67e-2)" "unprognostic (1.05e-1)" P2RY8 P2Y8 ENSG00000182162 "P2Y receptor family member 8" Q86VZ1 X 1462581-1537185 "Cancer-related genes, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 30.8;lymphoid tissue: 39.1" "Cell type enhanced" "Detected in some" "B-cells: 41.6;NK-cells: 71.0;Plasma cells: 33.7;T-cells: 42.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 20 "Leukemia: 63.3;lymphoma: 94.3;Myeloma: 49.0" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - T-cells" "Low region specificity" "Detected in many" HPA003631 Enhanced NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 19: NK-cells - Adaptive immune response" "HPA003631: AB_1079543" "unprognostic (4.32e-2)" "unprognostic (3.22e-5)" "unprognostic (6.31e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "prognostic favorable (7.80e-5)" "prognostic favorable (1.73e-4)" "unprognostic (5.27e-3)" "unprognostic (5.76e-3)" "unprognostic (5.52e-3)" "prognostic favorable (6.54e-4)" "unprognostic (4.29e-2)" "unprognostic (8.45e-3)" "unprognostic (2.90e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-1)" "unprognostic (2.80e-1)" PRLHR "GPR10, PrRPR" ENSG00000119973 "Prolactin releasing hormone receptor" P49683 10 118589997-118595648 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 5.0;pituitary gland: 6.8;smooth muscle: 3.3" "Group enriched" "Detected in some" 4 "Horizontal cells: 2.5;Inhibitory neurons: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 1.5;prostate cancer: 1.4" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" HPA039361 Enhanced NA NA "Cluster 64: Neuronal - Transcription" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA039361: AB_10673527" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (1.22e-1)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (9.09e-2)" PROKR1 "GPR73, GPR73a, PKR1, ZAQ" ENSG00000169618 "Prokineticin receptor 1" Q8TCW9 2 68643579-68658251 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 1.6;adrenal gland: 1.1;epididymis: 3.5" "Cell type enhanced" "Detected in single" "Adipocytes: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 3.4;Neuroblastoma: 1.2" "Colon - Colon enteroendocrine cells" "Region enhanced" "Detected in many" "spinal cord: 9.0" HPA029396 Uncertain NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" "HPA029396: AB_10610285" "unprognostic (5.46e-2)" "unprognostic (1.60e-2)" "unprognostic (8.75e-2)" "unprognostic (4.99e-4)" "unprognostic (1.18e-1)" "unprognostic (2.55e-3)" "unprognostic (1.07e-1)" "unprognostic (2.91e-2)" "unprognostic (1.85e-1)" "unprognostic (4.52e-2)" "unprognostic (1.89e-1)" "unprognostic (9.72e-2)" "unprognostic (8.96e-7)" "unprognostic (4.07e-2)" "unprognostic (2.53e-1)" "unprognostic (4.19e-1)" "unprognostic (7.22e-2)" PROKR2 "dJ680N4.3, GPR73b, GPR73L1, GPRg2, KAL3, PKR2" ENSG00000101292 "Prokineticin receptor 2" Q8NFJ6 20 5299218-5316954 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 1.9;Cone photoreceptor cells: 1.7;Early spermatids: 2.2;Granulosa cells: 2.8;Horizontal cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 17.0" "Low region specificity" "Detected in all" HPA047281 Uncertain NA NA "Cluster 17: Neuronal - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 18: Early spermatids - Unknown function" 5 "HPA047281: AB_10960057" "unprognostic (1.36e-1)" "unprognostic (1.69e-1)" PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 40.6;lymphoid tissue: 29.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 36.4;granulocytes: 74.7;Hofbauer cells: 76.0;Ionocytes: 32.0;Kupffer cells: 83.2;Langerhans cells: 86.2;Macrophages: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.9;eosinophil: 908.6;neutrophil: 749.9" "Group enriched" "Detected in many" 5 "granulocytes: 908.6;monocytes: 256.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 22.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Macrophages - Innate immune response" 2 "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" PTGDR "DP, DP1, PTGDR1" ENSG00000168229 "Prostaglandin D2 receptor" Q13258 14 52267698-52276724 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Mast cell degranulation" "G-protein coupled receptor, Receptor, Transducer" "Asthma, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 7.6;lymphoid tissue: 6.1" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 16.2;NK-cells: 116.8;T-cells: 29.2;Undifferentiated cells: 30.6" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "gdT-cell: 68.2;MAIT T-cell: 33.5;memory CD8 T-cell: 40.9;naive CD8 T-cell: 22.6;NK-cell: 90.5" "Group enriched" "Detected in many" 33 "NK-cells: 90.5;T-cells: 68.2" "Cancer enhanced" "Detected in single" "Leukemia: 1.7" "Adipose visceral - T-cells, Kidney - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Stomach - Fibroblasts, Thyroid - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA046586, HPA049668" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 17: Choroid plexus - Cilium" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: NK-cells - Adaptive immune response" "Plasma membrane, Cytosol" "HPA046586: , HPA049668: " "unprognostic (9.32e-3)" "unprognostic (3.31e-2)" "unprognostic (1.00e-2)" "unprognostic (2.04e-3)" "unprognostic (4.80e-2)" "unprognostic (2.70e-2)" "unprognostic (3.11e-3)" "unprognostic (5.00e-2)" "unprognostic (9.38e-3)" "unprognostic (4.94e-2)" "unprognostic (1.81e-2)" "unprognostic (1.54e-1)" "unprognostic (5.60e-8)" "unprognostic (1.14e-2)" "unprognostic (2.32e-1)" "unprognostic (4.02e-2)" "unprognostic (5.89e-2)" PTGDR2 "CD294, CRTH2, DP2, GPR44" ENSG00000183134 "Prostaglandin D2 receptor 2" Q9Y5Y4 11 60850933-60855950 "CD markers, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 8.0;skeletal muscle: 7.1;stomach 1: 9.0" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.7;granulocytes: 3.3;Intestinal goblet cells: 2.3;Langerhans cells: 2.7;Microglial cells: 1.8;monocytes: 7.6;Muller glia cells: 2.3;Smooth muscle cells: 3.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "basophil: 178.8;eosinophil: 234.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 234.5" "Cancer enriched" "Detected in single" 6 "Leukemia: 3.4" "Liver - Hepatocytes, Pancreas - Alpha cells, Pancreas - Beta cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA014259 Uncertain NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 23: Non-specific - Cellular respiration" "Cluster 47: Endothelial cells - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA014259: AB_1849304" "unprognostic (9.77e-2)" "unprognostic (1.35e-3)" "unprognostic (5.45e-3)" "unprognostic (1.69e-1)" "unprognostic (1.90e-1)" "unprognostic (1.85e-3)" "unprognostic (1.70e-1)" "unprognostic (2.30e-4)" "unprognostic (2.61e-1)" "unprognostic (7.92e-2)" "unprognostic (8.68e-3)" "unprognostic (1.52e-1)" "unprognostic (1.32e-2)" "unprognostic (1.52e-1)" "unprognostic (3.31e-1)" "unprognostic (1.49e-1)" "unprognostic (4.99e-2)" PTGER1 EP1 ENSG00000160951 "Prostaglandin E receptor 1" P34995 19 14472466-14475354 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 30.1" "Cell type enriched" "Detected in some" 16 "Collecting duct cells: 83.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.6" "Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" "unprognostic (3.44e-2)" "unprognostic (3.31e-1)" "unprognostic (2.68e-1)" "unprognostic (3.50e-4)" "unprognostic (8.69e-2)" "unprognostic (5.58e-2)" "unprognostic (2.39e-2)" "unprognostic (3.19e-2)" "unprognostic (2.05e-1)" "unprognostic (3.53e-2)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (7.74e-8)" "unprognostic (1.19e-1)" "unprognostic (4.41e-2)" "unprognostic (4.27e-3)" "unprognostic (4.88e-2)" PTGER2 EP2 ENSG00000125384 "Prostaglandin E receptor 2" P43116 14 52314305-52328598 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 37.9" "Cell type enhanced" "Detected in many" "Kupffer cells: 30.2;Macrophages: 35.1;monocytes: 108.6;NK-cells: 110.6;T-cells: 64.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 6.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 77: Bone marrow - Cell proliferation" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 19: NK-cells - Adaptive immune response" "unprognostic (1.48e-1)" "unprognostic (2.48e-2)" "unprognostic (1.36e-2)" "unprognostic (4.04e-3)" "unprognostic (1.55e-2)" "unprognostic (3.24e-1)" "unprognostic (3.11e-3)" "unprognostic (1.79e-1)" "unprognostic (2.42e-1)" "unprognostic (1.20e-3)" "unprognostic (1.18e-1)" "unprognostic (1.83e-1)" "prognostic unfavorable (4.16e-4)" "unprognostic (8.48e-3)" "unprognostic (5.26e-3)" "unprognostic (6.71e-2)" "unprognostic (5.74e-2)" PTGER3 "EP3, lnc003875" ENSG00000050628 "Prostaglandin E receptor 3" P43115 1 70852353-71047816 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 52.2;endometrium 1: 90.7;kidney: 77.9;smooth muscle: 65.5" "Group enriched" "Detected in many" 5 "Distal tubular cells: 156.7;Langerhans cells: 93.2;Mesothelial cells: 50.2" "Group enriched" "Detected in some" 7 "breast cancer: 4.1;renal cancer: 9.4" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 62 "basophil: 40.2" "Lineage enriched" "Detected in single" 62 "granulocytes: 40.2" "Cancer enriched" "Detected in some" 6 "Bone cancer: 47.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010689 Uncertain NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 51: Thyroid gland - Unknown function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 28: Dendritic cells - Antigen presentation" "HPA010689: AB_1855883" "unprognostic (1.53e-3)" "unprognostic (3.48e-1)" "unprognostic (1.11e-1)" "unprognostic (3.86e-3)" "unprognostic (1.47e-1)" "unprognostic (3.37e-2)" "unprognostic (4.80e-2)" "unprognostic (2.01e-2)" "unprognostic (1.24e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (3.50e-4)" "unprognostic (8.83e-3)" "unprognostic (1.86e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-4)" PTGER4 EP4 ENSG00000171522 "Prostaglandin E receptor 4" P35408 5 40679915-40693735 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.8;pancreas: 52.5" "Cell type enhanced" "Detected in many" "Langerhans cells: 144.6;monocytes: 379.9;NK-cells: 165.9;T-cells: 243.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA011226, HPA012756" Approved NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 40: Non-specific - Transcription" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 78: NK-cells & T-cells - Immune system & Transcription" "HPA011226: AB_1855885, HPA012756: AB_1855884" "unprognostic (1.79e-2)" "unprognostic (6.53e-3)" "unprognostic (9.43e-3)" "unprognostic (6.77e-3)" "unprognostic (1.44e-1)" "unprognostic (7.16e-2)" "unprognostic (7.28e-3)" "unprognostic (1.86e-2)" "unprognostic (2.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.02e-1)" "unprognostic (2.76e-1)" "unprognostic (3.61e-2)" "unprognostic (2.17e-1)" "unprognostic (2.48e-2)" "unprognostic (1.44e-1)" "prognostic favorable (2.48e-4)" PTGFR FP ENSG00000122420 "Prostaglandin F receptor" P43088 1 78303884-78540701 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 19.3" "Cell type enhanced" "Detected in some" "Club cells: 21.9;Collecting duct cells: 11.7;Fibroblasts: 27.5;Inhibitory neurons: 9.9;Late spermatids: 10.9;Microglial cells: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 6.9;prostate cancer: 6.4" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 29: Forebrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 53: Fibroblasts - ECM organization" "unprognostic (4.14e-2)" "unprognostic (1.35e-2)" "unprognostic (5.89e-3)" "unprognostic (6.03e-2)" "unprognostic (5.63e-2)" "unprognostic (1.45e-3)" "unprognostic (7.61e-2)" "unprognostic (2.25e-1)" "unprognostic (9.90e-2)" "unprognostic (8.46e-4)" "unprognostic (2.21e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-4)" "unprognostic (3.21e-4)" "unprognostic (8.48e-2)" "unprognostic (2.16e-2)" "unprognostic (1.21e-3)" PTGIR IP ENSG00000160013 "Prostaglandin I2 receptor" P43119 19 46620468-46625089 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 53.8" "Cell type enriched" "Detected in some" 6 "Langerhans cells: 239.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 10 "classical monocyte: 28.3;intermediate monocyte: 65.3;myeloid DC: 20.9;non-classical monocyte: 38.9" "Group enriched" "Detected in many" 11 "dendritic cells: 20.9;monocytes: 65.3" "Cancer enhanced" "Detected in some" "Leukemia: 6.4;Neuroblastoma: 7.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 7: Adipose tissue - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 14: Langerhans cells - Innate immune response" "unprognostic (3.79e-1)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (2.39e-1)" "unprognostic (1.03e-1)" "unprognostic (3.49e-3)" "unprognostic (4.22e-2)" "unprognostic (6.09e-2)" "unprognostic (2.12e-1)" "unprognostic (7.45e-2)" "unprognostic (4.47e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (2.09e-8)" "unprognostic (1.66e-2)" "prognostic unfavorable (1.74e-4)" "unprognostic (1.16e-1)" "unprognostic (5.66e-2)" PTH1R "PTHR, PTHR1" ENSG00000160801 "Parathyroid hormone 1 receptor" Q03431 3 46877721-46903799 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "kidney: 570.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 33.1;Distal tubular cells: 49.2;Extravillous trophoblasts: 72.7;Late spermatids: 31.5;Proximal tubular cells: 214.6;Sertoli cells: 57.1" "Group enriched" "Detected in many" 4 "renal cancer: 18.8;testis cancer: 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 4.8" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075879 Enhanced NA NA "Cluster 52: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Proximal tubular cells - Transmembrane transport" 9 "HPA075879: " "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (2.24e-5)" "unprognostic (7.46e-2)" "unprognostic (3.46e-1)" "unprognostic (5.02e-2)" "unprognostic (3.84e-3)" "unprognostic (5.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (7.51e-2)" "unprognostic (8.44e-2)" "prognostic favorable (6.79e-6)" "unprognostic (4.22e-3)" "unprognostic (1.50e-1)" "unprognostic (1.35e-4)" "unprognostic (6.62e-3)" PTH2R PTHR2 ENSG00000144407 "Parathyroid hormone 2 receptor" P49190 2 208359714-208854503 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 15.9" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 11.9;Excitatory neurons: 15.4;Proximal tubular cells: 14.6;Rod photoreceptor cells: 24.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA010655 Approved NA NA "Cluster 76: Retina - Visual perception" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 47: Leukemia - Hemostasis" "Cluster 34: Neurons - Neuronal signaling" 2 "HPA010655: AB_2668333" "unprognostic (4.76e-3)" "unprognostic (1.39e-3)" "unprognostic (1.64e-1)" "unprognostic (5.78e-2)" "unprognostic (3.77e-1)" "unprognostic (8.28e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (3.45e-2)" "unprognostic (2.14e-2)" "unprognostic (1.70e-1)" "unprognostic (1.09e-3)" "unprognostic (2.54e-3)" "unprognostic (6.87e-2)" "unprognostic (1.30e-2)" "unprognostic (1.37e-2)" QRFPR GPR103 ENSG00000186867 "Pyroglutamylated RFamide peptide receptor" Q96P65 4 121328642-121381059 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;heart muscle: 1.4;kidney: 1.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 7.2;Early spermatids: 2.4;Endothelial cells: 2.1;Excitatory neurons: 5.6;Inhibitory neurons: 10.5;Microglial cells: 2.7" "Cancer enriched" "Detected in some" 6 "renal cancer: 5.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Bone cancer: 3.8;Kidney cancer: 4.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA050236 Approved NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Neurons - Neuronal signaling" 1 "HPA050236: " "unprognostic (1.24e-2)" "unprognostic (2.30e-1)" "unprognostic (1.93e-2)" "unprognostic (3.21e-1)" "unprognostic (2.77e-1)" "unprognostic (3.21e-4)" "unprognostic (2.71e-1)" "unprognostic (5.77e-3)" "unprognostic (5.37e-2)" "unprognostic (6.33e-2)" "unprognostic (2.12e-1)" "prognostic favorable (3.09e-4)" "unprognostic (3.09e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" RGR RP44 ENSG00000148604 "Retinal G protein coupled receptor" P47804 10 84230666-84259960 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "retina: 134.8" "Cell type enriched" "Detected in some" 39 "Muller glia cells: 1357.4" "Cancer enriched" "Detected in single" 4 "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "midbrain: 25.5;olfactory bulb: 55.9;thalamus: 29.6" HPA059149 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 39: Retina & Testis - Cilium" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Muller glia cells - Visual perception" 1 Vesicles "Plasma membrane, Cytosol" "HPA059149: " "unprognostic (9.28e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (9.53e-2)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-1)" RHO "CSNBAD1, OPN2, RP4" ENSG00000163914 Rhodopsin P08100 3 129528639-129535344 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8215 "retina: 3936.5" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 3749.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in some" 4 "hippocampal formation: 9.7" "Region enhanced" "Detected in some" "cerebral cortex: 1.0;hippocampal formation: 1.5" "HPA013440, CAB022486, CAB034887, CAB034888" Enhanced NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 66: Photoreceptor cells - Visual perception" 2 "CAB022486: , CAB034887: AB_785511, CAB034888: AB_785512, HPA013440: AB_2668844" "unprognostic (4.32e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-1)" "unprognostic (1.83e-1)" "unprognostic (2.87e-1)" "unprognostic (1.94e-1)" "unprognostic (9.19e-11)" "unprognostic (4.24e-2)" "unprognostic (1.84e-1)" "unprognostic (2.91e-1)" RRH peropsin ENSG00000180245 "Retinal pigment epithelium-derived rhodopsin homolog" O14718 4 109827972-109849123 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 95 "retina: 73.3" "Cell type enriched" "Detected in some" 19 "Muller glia cells: 198.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" NA NA "Cluster 76: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 10: Muller glia cells - Visual perception" 1 "unprognostic (1.59e-1)" "unprognostic (2.47e-2)" "unprognostic (4.94e-2)" "unprognostic (1.96e-2)" "unprognostic (1.48e-1)" "unprognostic (5.25e-2)" "unprognostic (7.56e-2)" "unprognostic (8.47e-2)" "unprognostic (2.33e-1)" "unprognostic (1.86e-2)" "unprognostic (2.03e-2)" "unprognostic (1.62e-3)" "unprognostic (4.65e-1)" "unprognostic (4.38e-3)" "unprognostic (1.22e-1)" "unprognostic (2.27e-1)" "unprognostic (3.18e-2)" RXFP1 "LGR7, RXFPR1" ENSG00000171509 "Relaxin family peptide receptor 1" Q9HBX9 4 158315311-158653372 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.7;endometrium 1: 6.0" "Group enriched" "Detected in some" 6 "Excitatory neurons: 161.9;Glandular and luminal cells: 162.0" "Cancer enriched" "Detected in single" 9 "endometrial cancer: 3.9" "Group enriched" "Detected in many" 5 "basal ganglia: 12.0;cerebral cortex: 14.4;hypothalamus: 5.2;white matter: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "liver cancer: 6.6;ovarian cancer: 23.1;Uterine cancer: 13.5" "Kidney - Podocytes" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "cerebral cortex: 14.4;hippocampal formation: 9.3" HPA027067 Approved NA NA "Cluster 61: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Neurons - Neuronal signaling" "HPA027067: AB_10602127" "unprognostic (3.07e-3)" "unprognostic (3.02e-3)" "unprognostic (1.05e-1)" "unprognostic (2.53e-3)" "unprognostic (2.97e-2)" "unprognostic (4.15e-3)" "unprognostic (6.13e-2)" "unprognostic (6.18e-3)" "unprognostic (3.01e-1)" "unprognostic (5.14e-6)" "unprognostic (8.21e-2)" "unprognostic (1.34e-1)" "unprognostic (8.33e-4)" "unprognostic (3.24e-1)" "unprognostic (1.76e-1)" "unprognostic (1.31e-1)" "unprognostic (6.22e-3)" RXFP2 "GPR106, GREAT, INSL3R, LGR8, RXFPR2" ENSG00000133105 "Relaxin family peptide receptor 2" Q8WXD0 13 31739526-31803389 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 16 "Early spermatids: 11.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 10 "classical monocyte: 1.7" "Lineage enriched" "Detected in single" 18 "monocytes: 1.7" "Cancer enhanced" "Detected in single" "Sarcoma: 1.0" "Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 10 "basal ganglia: 3.8" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 33: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 18: Early spermatids - Unknown function" "unprognostic (1.77e-2)" RXFP3 "GPCR135, RLN3R1, RXFPR3, SALPR" ENSG00000182631 "Relaxin family peptide receptor 3" Q9NSD7 5 33936386-33938918 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA027833 Uncertain NA NA "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "HPA027833: AB_1849247" "unprognostic (1.93e-2)" "unprognostic (3.66e-1)" "unprognostic (2.89e-1)" "unprognostic (2.86e-1)" "unprognostic (9.68e-2)" "unprognostic (1.72e-1)" "unprognostic (8.67e-3)" RXFP4 "GPCR142, GPR100, RLN3R2, RXFPR4" ENSG00000173080 "Relaxin family peptide/INSL5 receptor 4" Q8TDU9 1 155941638-155943087 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "intestine: 1.7" "Cell type enriched" "Detected in some" 8 "Enteroendocrine cells: 51.1" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" NA NA "Cluster 45: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 "unprognostic (4.90e-2)" "unprognostic (2.17e-1)" "unprognostic (3.64e-2)" "unprognostic (1.84e-3)" "unprognostic (2.19e-1)" "unprognostic (5.94e-2)" "unprognostic (3.17e-2)" "unprognostic (4.73e-2)" "unprognostic (2.87e-1)" "unprognostic (8.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.19e-1)" "unprognostic (3.08e-3)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-1)" "unprognostic (3.86e-2)" S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 257.8;Endothelial cells: 150.8;Lymphatic endothelial cells: 76.8;NK-cells: 57.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1252.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Adipose tissue - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 41: Adipocytes & Endothelial cells - Mixed function" 1 Vesicles "CAB010104: AB_2238920, HPA075568: AB_2686758" "unprognostic (1.41e-1)" "unprognostic (9.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.61e-1)" "unprognostic (9.78e-2)" "unprognostic (4.49e-3)" "unprognostic (1.34e-3)" "unprognostic (1.99e-1)" "unprognostic (1.36e-1)" "unprognostic (9.12e-2)" "unprognostic (2.34e-2)" "unprognostic (2.23e-1)" "unprognostic (5.82e-3)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "prognostic unfavorable (8.78e-4)" S1PR2 "AGR16, DFNB68, EDG5, Gpcr13, H218" ENSG00000267534 "Sphingosine-1-phosphate receptor 2" O95136 19 10221433-10231331 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 89.4;Early spermatids: 71.9;Late spermatids: 198.9;Syncytiotrophoblasts: 61.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 44.9" "Group enriched" "Detected in many" 8 "granulocytes: 44.9;T-cells: 12.4" "Cancer enhanced" "Detected in many" "lymphoma: 30.8" "Breast - Fibroblasts, Prostate - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA014255, HPA014307" Approved Uncertain "Nuclear speckles,Golgi apparatus" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 62: Connective tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Cytotrophoblasts - Mitochondria" "Golgi apparatus" "Nuclear speckles" "HPA014255: , HPA014307: AB_1847989" "unprognostic (5.38e-3)" "unprognostic (1.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" "unprognostic (1.05e-3)" "unprognostic (8.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.84e-1)" "unprognostic (1.70e-1)" "unprognostic (7.40e-3)" "unprognostic (1.47e-2)" "prognostic unfavorable (4.36e-10)" "unprognostic (4.91e-2)" "unprognostic (4.56e-2)" "unprognostic (3.11e-1)" "unprognostic (8.09e-2)" S1PR3 "bA791O21.3, C9orf108, C9orf47, EDG-3, EDG3, FLJ37523" ENSG00000213694 "Sphingosine-1-phosphate receptor 3" Q99500 9 88990863-89005155 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 66.0;Fibroblasts: 28.1;Sertoli cells: 40.8;Smooth muscle cells: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "classical monocyte: 7.0" "Lineage enriched" "Detected in single" 18 "monocytes: 7.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 41: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 48: Smooth muscle cells - Signal transduction" 3 "prognostic favorable (5.91e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.91e-3)" "unprognostic (2.02e-1)" "unprognostic (4.41e-2)" "unprognostic (2.77e-2)" "unprognostic (5.22e-2)" "unprognostic (1.94e-2)" "unprognostic (3.15e-1)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (7.91e-6)" "unprognostic (4.43e-2)" "unprognostic (1.48e-2)" "unprognostic (3.93e-2)" "unprognostic (1.37e-1)" S1PR4 EDG6 ENSG00000125910 "Sphingosine-1-phosphate receptor 4" O95977 19 3172346-3180332 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 59.7" "Cell type enhanced" "Detected in many" "B-cells: 63.9;dendritic cells: 39.9;Hofbauer cells: 37.3;monocytes: 62.9;NK-cells: 117.6;T-cells: 73.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 45.8;lymphoma: 35.0;Myeloma: 24.7" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Prostate - T-cells, Stomach - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060601, HPA067232" Supported Mitochondria NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 81: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: NK-cells - Adaptive immune response" 1 Mitochondria "HPA060601: AB_2797261, HPA067232: AB_2797271" "prognostic favorable (3.13e-4)" "prognostic favorable (1.33e-4)" "unprognostic (2.58e-2)" "prognostic favorable (2.22e-4)" "unprognostic (2.98e-2)" "prognostic favorable (1.45e-6)" "unprognostic (1.27e-2)" "unprognostic (8.73e-2)" "unprognostic (1.21e-3)" "unprognostic (6.64e-3)" "unprognostic (3.59e-1)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (2.97e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (6.15e-3)" S1PR5 "Edg-8, EDG8" ENSG00000180739 "Sphingosine-1-phosphate receptor 5" Q9H228 19 10512742-10517931 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.6;brain: 33.3;skin 1: 14.1" "Cell type enriched" "Detected in some" 6 "NK-cells: 170.4" "Group enriched" "Detected in many" 5 "cervical cancer: 11.7;head and neck cancer: 8.0;lung cancer: 3.7;urothelial cancer: 6.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 300.0;MAIT T-cell: 185.0;memory CD8 T-cell: 144.8;naive CD8 T-cell: 109.2" "Lineage enriched" "Detected in many" 7 "T-cells: 300.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Liver - NK-cells (Liver), Lung - NK-cells (Lung), Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029683 Enhanced NA NA "Cluster 1: T-cells - Unknown function" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 19: NK-cells - Adaptive immune response" 2 "HPA029683: AB_10603237" "unprognostic (9.07e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-2)" "unprognostic (5.55e-4)" "unprognostic (4.21e-1)" "unprognostic (4.85e-2)" "unprognostic (9.30e-2)" "unprognostic (1.55e-1)" "unprognostic (3.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.81e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.71e-7)" "unprognostic (2.46e-2)" "unprognostic (2.90e-2)" "unprognostic (1.19e-1)" "unprognostic (1.52e-1)" SCTR ENSG00000080293 "Secretin receptor" P47872 2 119439843-119525301 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 25.8;pancreas: 66.0" "Group enriched" "Detected in some" 5 "Alveolar cells type 2: 29.6;Ductal cells: 96.2;Exocrine glandular cells: 95.2;Pancreatic endocrine cells: 28.9" "Cancer enhanced" "Detected in many" "pancreatic cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA007269 Uncertain NA NA "Cluster 15: Pancreas - Proteolysis" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Non-specific - Mixed function" "HPA007269: AB_1856640" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (4.99e-2)" "unprognostic (5.82e-2)" "unprognostic (1.71e-1)" "unprognostic (4.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (1.68e-2)" "unprognostic (9.08e-2)" "unprognostic (7.35e-2)" "unprognostic (2.38e-2)" "unprognostic (6.11e-3)" "unprognostic (1.65e-3)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (4.38e-2)" SMO "FZD11, SMOH" ENSG00000128602 "Smoothened, frizzled class receptor" Q99835 7 129188633-129213545 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 26.0;Leydig cells: 19.9;Muller glia cells: 13.7;Peritubular cells: 21.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Lung - Fibroblast_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011446 Approved NA NA "Cluster 53: Non-specific - Glycosylation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 6: Ovarian stromal cells - Transcription" 1 "CAB011446: " "unprognostic (2.48e-2)" "unprognostic (2.69e-2)" "unprognostic (7.09e-2)" "unprognostic (1.10e-1)" "unprognostic (8.16e-2)" "unprognostic (2.02e-1)" "unprognostic (3.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.38e-3)" "unprognostic (1.59e-1)" "unprognostic (1.17e-2)" "unprognostic (8.74e-3)" "unprognostic (1.62e-1)" "unprognostic (5.15e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-1)" "unprognostic (2.61e-2)" SSTR1 ENSG00000139874 "Somatostatin receptor 1" P30872 14 38207904-38213067 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2;intestine: 13.4;stomach 1: 21.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 9.0;Enteroendocrine cells: 25.1;Gastric mucus-secreting cells: 18.3;Oligodendrocyte precursor cells: 22.6;Paneth cells: 11.1;Proximal enterocytes: 10.9" "Cancer enhanced" "Detected in many" "prostate cancer: 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pancreas - Alpha cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003207, HPA031506" Approved Uncertain Vesicles NA NA "Cluster 25: Small intestine - Absorption" "Cluster 24: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 20: Enteroendocrine cells - Hormone signaling" 1 Vesicles "HPA003207: , HPA031506: AB_2673913" "unprognostic (1.40e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-1)" "unprognostic (2.50e-3)" "unprognostic (4.34e-2)" "unprognostic (9.90e-2)" "unprognostic (3.66e-3)" "unprognostic (1.91e-1)" "unprognostic (6.16e-3)" "unprognostic (3.20e-2)" "unprognostic (1.72e-2)" "unprognostic (9.19e-2)" "prognostic favorable (4.28e-4)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" "unprognostic (3.28e-2)" SSTR2 ENSG00000180616 "Somatostatin receptor 2" P30874 17 73165010-73176633 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 37.4;Enteroendocrine cells: 46.9;Horizontal cells: 76.2;Mucus glandular cells: 26.7;Smooth muscle cells: 43.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.2" "Cancer enhanced" "Detected in some" "Neuroblastoma: 18.2" "Breast - Endothelial cells, Pancreas - Alpha cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA007264 Uncertain Supported Cytosol NA NA "Cluster 22: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 48: Smooth muscle cells - Signal transduction" 3 Cytosol "HPA007264: AB_1080053" "unprognostic (2.13e-3)" "unprognostic (2.61e-3)" "unprognostic (7.43e-2)" "unprognostic (9.37e-3)" "unprognostic (6.25e-2)" "unprognostic (1.52e-1)" "unprognostic (2.29e-3)" "unprognostic (7.46e-2)" "unprognostic (2.96e-1)" "unprognostic (6.55e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.07e-1)" "prognostic unfavorable (9.04e-7)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (3.71e-3)" "unprognostic (2.95e-2)" SSTR3 ENSG00000278195 "Somatostatin receptor 3" P32745 22 37204237-37212477 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;lymphoid tissue: 10.8;testis: 7.6" "Group enriched" "Detected in some" 4 "Granulosa cells: 9.5;Sertoli cells: 10.9" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.1" "Lineage enriched" "Detected in single" 10 "T-cells: 1.1" "Cancer enriched" "Detected in some" 5 "Myeloma: 23.4" "Adipose visceral - Mesothelial cells, Breast - Plasma cells, Kidney - Podocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB022647 Approved NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 9: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 7: T-cells - T-cell receptor" 3 "CAB022647: " "unprognostic (1.63e-2)" "unprognostic (5.58e-3)" "unprognostic (1.32e-2)" "unprognostic (3.18e-2)" "unprognostic (7.03e-2)" "unprognostic (6.26e-5)" "unprognostic (1.11e-1)" "unprognostic (1.72e-2)" "unprognostic (1.90e-2)" "unprognostic (8.95e-2)" "unprognostic (3.88e-3)" "unprognostic (2.93e-1)" "unprognostic (1.51e-7)" "unprognostic (1.55e-1)" "unprognostic (1.24e-2)" "unprognostic (5.61e-3)" "unprognostic (1.06e-2)" SSTR4 ENSG00000132671 "Somatostatin receptor 4" P31391 20 23035312-23039237 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" HPA064252 Uncertain NA NA "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" 1 "HPA064252: AB_2685227" SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1072747-1081454 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 2.4;heart muscle: 6.7;kidney: 2.8;pituitary gland: 7.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 5.6" "Heart muscle - Cardiomyocytes, Pancreas - Beta cells" "Group enriched" "Detected in some" 5 "basal ganglia: 4.1;hypothalamus: 2.3" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" NA NA "Cluster 30: Heart muscle - Heart development" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 2: Mucus-secreting cells - Unknown function" 3 "Plasma membrane" "HPA066503: AB_2685679" "unprognostic (2.16e-2)" "unprognostic (7.31e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (9.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.09e-2)" SUCNR1 GPR91 ENSG00000198829 "Succinate receptor 1" Q9BXA5 3 151873643-151884619 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "kidney: 38.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 9.2;Hofbauer cells: 18.4;Kupffer cells: 18.8;Langerhans cells: 9.7;Macrophages: 13.0;monocytes: 9.8;Proximal tubular cells: 35.0;Smooth muscle cells: 8.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 11.9;Rhabdoid: 14.1" "Breast - Endothelial cells, Thyroid - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" CAB022745 Uncertain NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Kidney - Transmembrane transport" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Proximal tubular cells - Transmembrane transport" 2 "CAB022745: " "unprognostic (1.54e-1)" "unprognostic (2.65e-2)" "unprognostic (3.45e-2)" "unprognostic (6.94e-2)" "unprognostic (1.58e-1)" "unprognostic (6.01e-2)" "unprognostic (3.17e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.04e-1)" "unprognostic (8.92e-2)" "unprognostic (2.59e-1)" "unprognostic (1.34e-3)" "unprognostic (2.14e-1)" "unprognostic (4.14e-2)" "unprognostic (7.49e-2)" "unprognostic (1.58e-1)" TAAR1 "TA1, TAR1, TRAR1" ENSG00000146399 "Trace amine associated receptor 1" Q96RJ0 6 132643312-132659182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "stomach 1: 4.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "cervical cancer: 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 2.1" "Not detected" "Not detected" HPA055614 Approved NA NA "Cluster 48: Stomach - Proteolysis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Ciliated cells - Cilium assembly" "HPA055614: AB_2682862" "unprognostic (2.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" "unprognostic (2.68e-2)" TAAR2 GPR58 ENSG00000146378 "Trace amine associated receptor 2" Q9P1P5 6 132617022-132624275 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 2.0;Late spermatids: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Late spermatids - Unknown function" TAAR5 PNR ENSG00000135569 "Trace amine associated receptor 5" O14804 6 132588592-132589741 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA051703 Uncertain NA NA "Cluster 68: Cardiomyocytes - Muscle contraction" "HPA051703: AB_2681580" TAAR6 "TA4, TRAR4" ENSG00000146383 "Trace amine associated receptor 6" Q96RI8 6 132570322-132571359 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Neuronal - Sensory perception" "unprognostic (1.70e-1)" TAAR8 "GPR102, TA5, TAR5, TRAR5" ENSG00000146385 "Trace amine associated receptor 8" Q969N4 6 132552672-132553756 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 11: Neuronal - Sensory perception" TAAR9 "TA3, TAR3, TRAR3" ENSG00000237110 "Trace amine associated receptor 9" Q96RI9 6 132538277-132539336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 15: Kidney cancer - Membrane components" 1 TACR1 "NK1R, NKIR, SPR, TAC1R" ENSG00000115353 "Tachykinin receptor 1" P25103 2 75046463-75199520 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 6.0" "Cell type enriched" "Detected in some" 4 "Inhibitory neurons: 79.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 23 "basophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Group enriched" "Detected in some" 4 "Brain cancer: 2.9;ovarian cancer: 1.2" "Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA074573 Enhanced NA NA "Cluster 62: Connective tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Neurons - Synaptic function" 2 "HPA074573: AB_2686701" "unprognostic (5.74e-4)" "unprognostic (2.41e-3)" "unprognostic (1.46e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (8.62e-3)" "unprognostic (1.10e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-1)" "unprognostic (2.14e-3)" "unprognostic (1.63e-2)" "unprognostic (5.91e-4)" "unprognostic (1.03e-2)" "unprognostic (2.75e-1)" "unprognostic (1.06e-1)" "unprognostic (2.76e-2)" TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 176.9" "Cell type enhanced" "Detected in some" "Kupffer cells: 1.9;Leydig cells: 2.4;Ovarian stromal cells: 2.8;Serous glandular cells: 2.4;Sertoli cells: 2.7;Smooth muscle cells: 2.2" "Cancer enriched" "Detected in many" 4 "stomach cancer: 6.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Approved "Plasma membrane" NA NA "Cluster 45: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 32: Smooth muscle cells - Muscle contraction" "Plasma membrane" "HPA076573: AB_2732313" "unprognostic (2.83e-1)" "unprognostic (1.58e-3)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (4.22e-1)" "unprognostic (2.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.96e-2)" "unprognostic (3.72e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (9.88e-4)" "unprognostic (5.59e-3)" "unprognostic (4.31e-3)" "unprognostic (1.25e-3)" "unprognostic (1.32e-1)" TACR3 "NK3R, NKR, TAC3R" ENSG00000169836 "Tachykinin receptor 3" P29371 4 103586031-103719985 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 1.3;retina: 2.6;urinary bladder: 1.8" "Group enriched" "Detected in some" 8 "Bipolar cells: 11.5;Excitatory neurons: 6.5;Extravillous trophoblasts: 5.4;Oligodendrocytes: 9.8;Oocytes: 6.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "pons: 18.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 21 "Sarcoma: 2.9" "Kidney - Podocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA009418 Uncertain NA NA "Cluster 76: Retina - Visual perception" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 2: Skeletal myocytes - Muscle contraction" "HPA009418: AB_1857727" "unprognostic (3.81e-2)" "unprognostic (2.92e-1)" "unprognostic (2.29e-1)" "unprognostic (3.50e-1)" "unprognostic (3.21e-1)" "unprognostic (5.52e-1)" "unprognostic (3.80e-1)" "unprognostic (3.42e-2)" "unprognostic (1.72e-2)" TAS1R1 "GPR70, T1R1, TR1" ENSG00000173662 "Taste 1 receptor member 1" Q7RTX1 1 6555307-6579755 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 5 "testis: 4.2" "Cell type enhanced" "Detected in some" "Early spermatids: 4.9;Late spermatids: 17.2;Schwann cells: 4.0;Spermatogonia: 2.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Myeloma: 1.7" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA034579, HPA034580" Approved NA NA "Cluster 44: Testis - Spermatogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 63: Late spermatids - Spermatogenesis" "HPA034579: AB_2674232, HPA034580: AB_10671504" "unprognostic (2.03e-2)" "unprognostic (9.29e-3)" "unprognostic (5.60e-4)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (4.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.53e-4)" "unprognostic (3.89e-2)" "unprognostic (3.15e-1)" "unprognostic (3.26e-2)" "unprognostic (3.17e-1)" "unprognostic (5.45e-3)" "unprognostic (1.67e-1)" "unprognostic (8.26e-2)" "unprognostic (8.28e-2)" "unprognostic (6.22e-2)" TAS1R2 "GPR71, T1R2, TR2" ENSG00000179002 "Taste 1 receptor member 2" Q8TE23 1 18839599-18859660 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAS1R3 T1R3 ENSG00000169962 "Taste 1 receptor member 3" Q7RTX0 1 1331280-1335314 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 11.9;lymphoid tissue: 3.6;salivary gland: 7.7" "Cell type enhanced" "Detected in some" "B-cells: 1.7;Plasma cells: 7.0;Serous glandular cells: 3.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "memory B-cell: 1.6" "Lineage enriched" "Detected in single" 17 "B-cells: 1.6" "Cancer enhanced" "Detected in some" "Myeloma: 7.0" "Breast - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA053439 Uncertain Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Plasma cells - Protein processing" "Plasma membrane" "Golgi apparatus" "HPA053439: AB_2682150" "unprognostic (1.35e-2)" "unprognostic (1.45e-1)" "unprognostic (6.85e-2)" "unprognostic (9.22e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-3)" "unprognostic (4.32e-2)" "unprognostic (2.05e-1)" "unprognostic (6.95e-2)" "unprognostic (4.22e-1)" "unprognostic (8.44e-3)" "unprognostic (7.59e-3)" "unprognostic (8.37e-2)" "unprognostic (1.18e-1)" "unprognostic (2.35e-1)" "unprognostic (1.11e-3)" "unprognostic (1.04e-1)" TAS2R1 "T2R1, TRB7" ENSG00000169777 "Taste 2 receptor member 1" Q9NYW7 5 9627347-9712378 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 7.3" "Group enriched" "Detected in some" 20 "Early spermatids: 26.2;Late spermatids: 75.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA051879 Uncertain NA NA "Cluster 20: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 11: Late spermatids - Unknown function" "HPA051879: AB_2681649" "unprognostic (2.19e-1)" TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825219-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "Astrocytes: 5.9;Excitatory neurons: 13.9;Inhibitory neurons: 13.8;Microglial cells: 4.5;Oligodendrocyte precursor cells: 13.2;Oligodendrocytes: 10.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Neurons - Synaptic function" 4 "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (1.28e-1)" "unprognostic (3.89e-4)" "unprognostic (1.77e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.82e-3)" "unprognostic (3.86e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-5)" "unprognostic (5.41e-2)" "unprognostic (3.18e-2)" "unprognostic (2.87e-2)" "unprognostic (2.56e-3)" TAS2R13 "T2R13, TRB3" ENSG00000212128 "Taste 2 receptor member 13" Q9NYV9 12 10907926-10909562 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Horizontal cells: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "unprognostic (2.78e-1)" "unprognostic (3.66e-2)" "unprognostic (1.77e-1)" "unprognostic (5.48e-2)" "unprognostic (1.52e-3)" "unprognostic (6.66e-3)" "unprognostic (4.50e-2)" "unprognostic (8.80e-2)" TAS2R14 "T2R14, TRB1" ENSG00000212127 "Taste 2 receptor member 14" Q9NYV8 12 10937408-11171573 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 5.4;Distal tubular cells: 6.1;Horizontal cells: 6.9;Rod photoreceptor cells: 7.2;Skeletal myocytes: 6.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 66: Photoreceptor cells - Visual perception" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (4.26e-2)" "unprognostic (1.41e-1)" "unprognostic (6.16e-2)" "unprognostic (4.55e-2)" "unprognostic (1.46e-2)" "unprognostic (1.78e-1)" "unprognostic (9.85e-3)" "unprognostic (1.18e-1)" "unprognostic (1.12e-3)" "unprognostic (1.93e-2)" "unprognostic (1.22e-4)" "unprognostic (2.45e-2)" "unprognostic (1.07e-1)" "unprognostic (9.29e-3)" "unprognostic (4.71e-3)" TAS2R16 T2R16 ENSG00000128519 "Taste 2 receptor member 16" Q9NYV7 7 122994704-122995700 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAS2R19 "T2R19, T2R23, TAS2R23, TAS2R48" ENSG00000212124 "Taste 2 receptor member 19" P59542 12 11021619-11022620 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in single" "Prostatic glandular cells: 1.2" "Cancer enhanced" "Detected in single" "testis cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 40: Prostatic glandular cells - Transcription" 6 "unprognostic (1.90e-2)" "unprognostic (9.54e-2)" "unprognostic (1.83e-1)" "unprognostic (5.18e-3)" "unprognostic (1.84e-1)" "unprognostic (2.56e-1)" "unprognostic (1.50e-2)" "unprognostic (5.73e-2)" "unprognostic (2.35e-1)" "unprognostic (8.76e-2)" "unprognostic (8.26e-2)" "unprognostic (1.94e-2)" "unprognostic (1.57e-8)" "unprognostic (9.08e-2)" "unprognostic (1.58e-1)" "unprognostic (7.96e-2)" "unprognostic (4.32e-1)" TAS2R20 "T2R20, T2R56, TAS2R49" ENSG00000255837 "Taste 2 receptor member 20" P59543 12 10995961-10998304 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 49: Non-specific - Transcription" "unprognostic (4.62e-2)" "unprognostic (2.96e-1)" "unprognostic (1.12e-3)" "unprognostic (2.16e-4)" "unprognostic (2.92e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (6.98e-2)" "unprognostic (5.14e-4)" "unprognostic (6.23e-3)" "unprognostic (1.27e-9)" "unprognostic (2.68e-1)" "unprognostic (3.35e-2)" "unprognostic (1.28e-2)" "unprognostic (6.44e-3)" TAS2R3 T2R3 ENSG00000127362 "Taste 2 receptor member 3" Q9NYW6 7 141764097-141765197 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "unprognostic (4.11e-2)" "unprognostic (2.27e-1)" "unprognostic (4.40e-2)" "unprognostic (7.38e-2)" "unprognostic (4.04e-1)" "unprognostic (1.51e-2)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" TAS2R30 "T2R30, TAS2R47" ENSG00000256188 "Taste 2 receptor member 30" P59541 12 11132958-11134644 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 1.7;monocytes: 1.7;Rod photoreceptor cells: 2.0;Skeletal myocytes: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Non-specific - Transcription" "unprognostic (7.19e-3)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (3.17e-1)" "unprognostic (1.71e-1)" "unprognostic (4.02e-1)" "unprognostic (7.01e-6)" "unprognostic (4.48e-2)" "unprognostic (1.26e-1)" "unprognostic (1.11e-1)" "unprognostic (4.14e-1)" TAS2R31 "T2R31, T2R53, TAS2R44" ENSG00000256436 "Taste 2 receptor member 31" P59538 12 11030387-11031407 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.2;Endothelial cells: 1.5;Horizontal cells: 1.3;Prostatic glandular cells: 1.0;Rod photoreceptor cells: 1.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Non-specific - Transcription" "unprognostic (2.23e-2)" "unprognostic (3.80e-1)" "unprognostic (2.85e-2)" "unprognostic (4.70e-3)" "unprognostic (2.16e-1)" "unprognostic (9.07e-2)" "unprognostic (3.33e-1)" "unprognostic (2.77e-1)" "unprognostic (2.77e-1)" "unprognostic (1.60e-2)" "unprognostic (2.72e-2)" "unprognostic (4.32e-2)" "unprognostic (7.54e-4)" "unprognostic (2.99e-2)" "unprognostic (1.87e-1)" "unprognostic (6.53e-3)" "unprognostic (1.83e-1)" TAS2R38 "PTC, T2R61" ENSG00000257138 "Taste 2 receptor member 38" P59533 7 141972631-141973773 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 2.0;lung cancer: 1.1" "Not detected" "Not detected" "HPA043862, HPA054366" Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "HPA043862: AB_2678703, HPA054366: AB_2682464" "unprognostic (5.18e-3)" "unprognostic (6.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.58e-1)" "unprognostic (1.25e-1)" "unprognostic (8.36e-2)" "unprognostic (5.86e-2)" "unprognostic (8.05e-2)" TAS2R39 ENSG00000236398 "Taste 2 receptor member 39" P59534 7 143183419-143184435 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA060680 Uncertain NA NA "Cluster 30: White matter - Myelination" "Cluster 48: Smooth muscle cells - Signal transduction" "HPA060680: AB_2684341" TAS2R4 T2R4 ENSG00000127364 "Taste 2 receptor member 4" Q9NYW5 7 141776674-141781691 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 5.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 7.7;Horizontal cells: 8.2;Prostatic glandular cells: 6.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 65: Cerebellum - Nervous system development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 55: Non-specific - Transcription" "unprognostic (6.15e-3)" "unprognostic (5.80e-2)" "unprognostic (1.57e-1)" "unprognostic (1.39e-2)" "unprognostic (2.25e-1)" "unprognostic (1.55e-3)" "unprognostic (1.00e-2)" "unprognostic (3.86e-2)" "unprognostic (7.95e-3)" "unprognostic (2.06e-1)" "unprognostic (3.76e-3)" "unprognostic (6.15e-3)" "unprognostic (1.04e-5)" "unprognostic (5.58e-2)" "unprognostic (1.35e-1)" "unprognostic (9.87e-2)" "unprognostic (1.18e-1)" TAS2R40 GPR60 ENSG00000221937 "Taste 2 receptor member 40" P59535 7 143222037-143223079 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.8" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.8" "Not detected" "Not detected" "Adipose visceral - Neutrophils" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 30: White matter - Myelination" TAS2R41 T2R59 ENSG00000221855 "Taste 2 receptor member 41" P59536 7 143477873-143478796 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057063 Uncertain NA NA "Cluster 16: Intestinal goblet cells - Mucin production" 1 "HPA057063: AB_2683324" TAS2R42 "hT2R55, T2R24, T2R55, TAS2R55" ENSG00000186136 "Taste 2 receptor member 42" Q7RTR8 12 11185993-11186937 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA036149 Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "HPA036149: AB_10672080" "unprognostic (2.45e-2)" "unprognostic (4.17e-2)" TAS2R43 T2R52 ENSG00000255374 "Taste 2 receptor member 43" P59537 12 11091287-11092313 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 60: Prostate cancer - Unknown function" "Cluster 74: Neutrophils - Degranulation" "unprognostic (5.69e-3)" "unprognostic (1.48e-1)" "unprognostic (2.19e-1)" "unprognostic (1.48e-2)" "unprognostic (2.67e-1)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (7.48e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-1)" "unprognostic (3.49e-1)" "unprognostic (1.59e-1)" TAS2R46 T2R54 ENSG00000226761 "Taste 2 receptor member 46" P59540 12 11061365-11062294 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Bipolar cells: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 30: White matter - Myelination" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" "unprognostic (9.02e-2)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (7.73e-4)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" TAS2R5 T2R5 ENSG00000127366 "Taste 2 receptor member 5" Q9NYW4 7 141790217-141791367 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA053742 Approved "Nucleoplasm,Nucleoli,Cytoplasmic bodies" NA NA "Cluster 66: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 76: Oligodendrocyte precursor - Unknown function" 6 "Nucleoplasm, Nucleoli" "Cytoplasmic bodies" "HPA053742: " "unprognostic (5.48e-3)" "unprognostic (3.90e-3)" "unprognostic (6.07e-2)" "unprognostic (8.00e-3)" "unprognostic (7.56e-2)" "unprognostic (4.87e-2)" "unprognostic (1.90e-1)" "unprognostic (1.71e-1)" "unprognostic (2.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.13e-5)" "unprognostic (1.13e-2)" "unprognostic (8.29e-7)" "unprognostic (1.29e-1)" "unprognostic (3.28e-1)" "unprognostic (6.92e-2)" "unprognostic (1.39e-2)" TAS2R50 T2R51 ENSG00000212126 "Taste 2 receptor member 50" P59544 12 10985913-10986912 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 49: Non-specific - Transcription" "unprognostic (6.55e-2)" "unprognostic (4.25e-1)" "unprognostic (1.14e-1)" "unprognostic (1.78e-1)" "unprognostic (2.53e-2)" "unprognostic (2.94e-1)" "unprognostic (2.24e-1)" "unprognostic (1.73e-1)" TAS2R60 T2R60 ENSG00000185899 "Taste 2 receptor member 60" P59551 7 143443453-143444409 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA030416 Uncertain NA NA "Cluster 24: Non-specific - Unknown function" "Cluster 58: Macrophages - Innate immune response" "HPA030416: AB_10603344" "unprognostic (1.78e-2)" "unprognostic (7.98e-2)" TAS2R7 "T2R7, TRB4" ENSG00000121377 "Taste 2 receptor member 7" Q9NYW3 12 10801532-10802627 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA TAS2R8 "T2R8, TRB5" ENSG00000121314 "Taste 2 receptor member 8" Q9NYW2 12 10806051-10807286 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 65: Neurons - Synaptic function" TAS2R9 "T2R9, TRB6" ENSG00000121381 "Taste 2 receptor member 9" Q9NYW1 12 10809094-10810168 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 73: B-cells - B-cell function" TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594507-3606875 "Disease related genes, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 10.4;Endothelial cells: 8.6;Fibroblasts: 4.8;Lymphatic endothelial cells: 13.2;Schwann cells: 7.3;Smooth muscle cells: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077366 Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 47: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 57: Platelets - Hemostasis" 1 "Plasma membrane" "Nuclear speckles" "HPA077366: AB_2686836" "unprognostic (1.59e-1)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (8.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.52e-2)" "unprognostic (2.17e-3)" "unprognostic (8.41e-2)" "unprognostic (6.25e-2)" "prognostic favorable (7.17e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (4.32e-2)" "unprognostic (9.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.02e-1)" TRHR ENSG00000174417 "Thyrotropin releasing hormone receptor" P34981 8 109086585-109121565 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA055162 Approved NA NA "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 65: Neurons - Synaptic function" 13 "HPA055162: AB_2732592" "unprognostic (1.92e-2)" "unprognostic (8.58e-2)" "unprognostic (1.17e-1)" TSHR LGR3 ENSG00000165409 "Thyroid stimulating hormone receptor" P16473 14 80954989-81146306 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Congenital hypothyroidism, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "thyroid gland: 265.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 6.7;Inhibitory neurons: 11.8;Langerhans cells: 7.2;Microglial cells: 6.3;Oligodendrocytes: 8.8;Plasma cells: 14.3" "Cancer enriched" "Detected in some" 116 "thyroid cancer: 100.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "naive B-cell: 1.7;T-reg: 6.9" "Group enriched" "Detected in many" 5 "B-cells: 1.7;T-cells: 6.9" "Cancer enhanced" "Detected in some" "Myeloma: 10.0" "Testis - Late spermatids, Thyroid - Thyroid glandular cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "hypothalamus: 1.8" CAB000473 Approved "Intracellular and membrane" Receptor NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 51: Thyroid gland - Unknown function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 61: Plasma cells - Immunoglobulins & histones" 4 "CAB000473: AB_2303782" "unprognostic (3.36e-3)" "unprognostic (1.31e-3)" "unprognostic (1.02e-2)" "unprognostic (4.17e-6)" "unprognostic (3.01e-3)" "unprognostic (1.85e-3)" "unprognostic (1.83e-1)" "unprognostic (2.66e-2)" "unprognostic (3.39e-2)" "unprognostic (2.60e-2)" "unprognostic (1.70e-1)" "unprognostic (7.11e-3)" "unprognostic (5.08e-7)" "unprognostic (1.32e-1)" "unprognostic (7.40e-2)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" UTS2R GPR14 ENSG00000181408 "Urotensin 2 receptor" Q9UKP6 17 82371765-82377458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "stomach cancer: 0.7;testis cancer: 2.2;thyroid cancer: 1.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 2.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.0" "Cancer enhanced" "Detected in many" "Myeloma: 22.0" "Heart muscle - Cardiomyocytes" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 21: Testis - Unknown function" "Cluster 48: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Plasma cells - Humoral immune response" "unprognostic (1.55e-3)" "unprognostic (1.17e-1)" "unprognostic (1.38e-1)" "unprognostic (3.92e-1)" "unprognostic (1.46e-2)" "unprognostic (8.26e-2)" "unprognostic (2.30e-2)" "unprognostic (3.98e-1)" "unprognostic (6.38e-2)" "unprognostic (4.44e-2)" "unprognostic (8.73e-2)" "unprognostic (1.81e-1)" "unprognostic (1.32e-1)" "unprognostic (7.84e-2)" VIPR1 "HVR1, RDC1, VPAC1, VPAC1R" ENSG00000114812 "Vasoactive intestinal peptide receptor 1" P32241 3 42489299-42537573 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 128.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 39.6;Distal enterocytes: 54.6;Intestinal goblet cells: 52.2;Paneth cells: 89.4;Proximal enterocytes: 45.2" "Cancer enhanced" "Detected in many" "prostate cancer: 10.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 22 "dendritic cells: 2.1;monocytes: 1.8;T-cells: 2.7" "Cancer enhanced" "Detected in many" "pancreatic cancer: 22.7" "Colon - Colon enterocytes, Prostate - Prostate glandular cells" "Group enriched" "Detected in many" 4 "amygdala: 6.4;basal ganglia: 4.5;cerebral cortex: 9.6;hippocampal formation: 7.7;white matter: 2.5" "Low region specificity" "Detected in all" HPA026777 Approved NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 45: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 16: Intestinal goblet cells - Mucin production" "HPA026777: AB_10604003" "unprognostic (9.02e-2)" "unprognostic (9.34e-3)" "unprognostic (3.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (8.89e-4)" "unprognostic (4.00e-3)" "unprognostic (1.03e-1)" "unprognostic (2.95e-2)" "unprognostic (1.28e-2)" "unprognostic (2.72e-1)" "unprognostic (1.82e-3)" "unprognostic (7.70e-2)" "unprognostic (1.69e-1)" "unprognostic (1.03e-2)" "unprognostic (1.05e-2)" VIPR2 "VPAC2, VPAC2R" ENSG00000106018 "Vasoactive intestinal peptide receptor 2" P41587 7 159028175-159144867 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "dendritic cells: 65.6;Mesothelial cells: 96.5;Muller glia cells: 32.2;Oligodendrocyte precursor cells: 46.7;Rod photoreceptor cells: 43.1" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "plasmacytoid DC: 12.3" "Lineage enriched" "Detected in single" 17 "dendritic cells: 12.3" "Cancer enhanced" "Detected in some" "Leukemia: 5.2;Rhabdoid: 3.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Region enhanced" "Detected in many" "olfactory bulb: 27.0" "Low region specificity" "Detected in many" HPA062707 Approved Approved "Focal adhesion sites" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Connective tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 28: Dendritic cells - Antigen presentation" "Focal adhesion sites" "HPA062707: AB_2684842" "unprognostic (3.65e-2)" "unprognostic (2.13e-2)" "unprognostic (4.26e-2)" "unprognostic (2.04e-2)" "unprognostic (6.31e-2)" "unprognostic (4.10e-2)" "unprognostic (1.03e-1)" "unprognostic (8.58e-2)" "unprognostic (2.32e-2)" "unprognostic (1.02e-1)" "unprognostic (9.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" VN1R1 "V1RL1, VNR19I1, ZVNH1, ZVNR1" ENSG00000178201 "Vomeronasal 1 receptor 1" Q9GZP7 19 57454790-57457140 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 6.9;retina: 8.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.6;Cone photoreceptor cells: 1.7;dendritic cells: 1.8;Horizontal cells: 4.4;Oligodendrocyte precursor cells: 2.4;Rod photoreceptor cells: 2.5;Skeletal myocytes: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" HPA062209 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 28: Neuronal - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 71: Horizontal & Bipolar cells - Neuronal signaling" Vesicles Nucleoplasm "HPA062209: " "unprognostic (7.11e-2)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (1.51e-2)" "unprognostic (5.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.84e-2)" "unprognostic (1.65e-3)" "unprognostic (1.21e-2)" "unprognostic (5.41e-2)" "unprognostic (5.68e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-2)" "unprognostic (4.59e-5)" VN1R2 V1RL2 ENSG00000196131 "Vomeronasal 1 receptor 2" Q8NFZ6 19 53258292-53261837 "G-protein coupled receptors, Predicted membrane proteins" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "Early spermatids: 13.3;Late spermatids: 11.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044551 Uncertain NA NA "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Non-specific - Sensory perception" "Cluster 11: Late spermatids - Unknown function" "HPA044551: AB_2678982" "unprognostic (9.54e-2)" "unprognostic (3.17e-1)" "unprognostic (1.06e-1)" VN1R4 V1RL4 ENSG00000228567 "Vomeronasal 1 receptor 4" Q7Z5H5 19 53266676-53267723 "G-protein coupled receptors, Predicted membrane proteins" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027018 Uncertain NA NA "Cluster 10: Ciliated cells - Ion channel activity" "HPA027018: AB_10603142" XCR1 "CCXCR1, GPR5" ENSG00000173578 "X-C motif chemokine receptor 1" P46094 3 46016990-46085825 "G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 8.5" "Cell type enriched" "Detected in some" 4 "Schwann cells: 32.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 24 "myeloid DC: 2.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA013169 Uncertain NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Lymphoid tissue - Cytokine signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Dendritic cells - Antigen presentation" 1 "HPA013169: AB_1846211" "unprognostic (3.49e-3)" "unprognostic (4.23e-3)" "unprognostic (1.15e-2)" "unprognostic (5.91e-3)" "unprognostic (7.91e-2)" "unprognostic (8.53e-6)" "unprognostic (3.89e-6)" "unprognostic (9.27e-3)" "unprognostic (4.41e-3)" "unprognostic (3.40e-3)" "unprognostic (2.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.87e-1)" "unprognostic (5.98e-2)" "unprognostic (1.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.80e-1)"