Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nCPM" "RNA single cell type group specificity" "RNA single cell type group distribution" "RNA single cell type group specificity score" "RNA single cell type group specific nCPM" "RNA single nuclei brain specificity" "RNA single nuclei brain distribution" "RNA single nuclei brain specificity score" "RNA single nuclei brain specific nCPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific pTPM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA tissue cell type enrichment" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" "Protein cell type specificity" "Protein cell type distribution" "Protein cell type specificity score" "Protein cell type specific Intensity" "Protein tissue specificity" "Protein tissue distribution" "Protein tissue specificity score" "Protein tissue specific Intensity" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "Secretome function" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Brain expression cluster" "Cell line expression cluster" "Single cell expression cluster" Interactions "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Cancer prognostics - Bladder Urothelial Carcinoma (TCGA)" "Cancer prognostics - Breast Invasive Carcinoma (TCGA)" "Cancer prognostics - Breast Invasive Carcinoma (validation)" "Cancer prognostics - Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA)" "Cancer prognostics - Colon Adenocarcinoma (TCGA)" "Cancer prognostics - Colon Adenocarcinoma (validation)" "Cancer prognostics - Glioblastoma Multiforme (TCGA)" "Cancer prognostics - Glioblastoma Multiforme (validation)" "Cancer prognostics - Head and Neck Squamous Cell Carcinoma (TCGA)" "Cancer prognostics - Kidney Chromophobe (TCGA)" "Cancer prognostics - Kidney Renal Clear Cell Carcinoma (TCGA)" "Cancer prognostics - Kidney Renal Clear Cell Carcinoma (validation)" "Cancer prognostics - Kidney Renal Papillary Cell Carcinoma (TCGA)" "Cancer prognostics - Liver Hepatocellular Carcinoma (TCGA)" "Cancer prognostics - Liver Hepatocellular Carcinoma (validation)" "Cancer prognostics - Lung Adenocarcinoma (TCGA)" "Cancer prognostics - Lung Adenocarcinoma (validation)" "Cancer prognostics - Lung Squamous Cell Carcinoma (TCGA)" "Cancer prognostics - Lung Squamous Cell Carcinoma (validation)" "Cancer prognostics - Ovary Serous Cystadenocarcinoma (TCGA)" "Cancer prognostics - Ovary Serous Cystadenocarcinoma (validation)" "Cancer prognostics - Pancreatic Adenocarcinoma (TCGA)" "Cancer prognostics - Pancreatic Adenocarcinoma (validation)" "Cancer prognostics - Prostate Adenocarcinoma (TCGA)" "Cancer prognostics - Rectum Adenocarcinoma (TCGA)" "Cancer prognostics - Rectum Adenocarcinoma (validation)" "Cancer prognostics - Skin Cutaneous Melanoma (TCGA)" "Cancer prognostics - Stomach Adenocarcinoma (TCGA)" "Cancer prognostics - Testicular Germ Cell Tumor (TCGA)" "Cancer prognostics - Thyroid Carcinoma (TCGA)" "Cancer prognostics - Uterine Corpus Endometrial Carcinoma (TCGA)" A4GALT "A14GALT, Gb3S, P(k), P1" ENSG00000128274 "Alpha 1,4-galactosyltransferase (P blood group)" Q9NPC4 22 42692121-42721298 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 11.5;Endometrial secretory cells: 13.6;Loop of henle epithelial cells: 17.7;Ocular epithelial cells: 14.3;Papillary tip epithelial cells: 47.1;Podocytes: 20.9;Proximal tubule cells: 58.5;Renal collecting duct intercalated cells: 21.8;Renal collecting duct principal cells: 10.5;Renal connecting tubule cells: 33.9;Respiratory secretory cells: 10.7" "Cell type enhanced" "Detected in many" "Ductal cells: 33.9;Renal nephron cells: 58.5" "Group enriched" "Detected in some" 13 "endothelial cell: 38.0;fibroblast: 52.5;pericyte: 67.6;vascular associated smooth muscle cell: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 104 "blood vessel: 15615.6;salivary gland: 5281.5" HPA001141 Uncertain Mitochondria NA NA 16000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 Mitochondria "HPA001141: " "unprognostic (6.58e-2)" "unprognostic (4.79e-2)" "unprognostic (4.77e-3)" "unprognostic (6.53e-2)" "unprognostic (8.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.59e-1)" "unprognostic (8.73e-2)" "unprognostic (8.49e-2)" "unprognostic (3.75e-3)" "potential prognostic favorable (2.49e-4)" "unprognostic (4.49e-3)" "unprognostic (2.83e-3)" "unprognostic (1.10e-1)" "unprognostic (2.66e-2)" "unprognostic (4.41e-3)" "unprognostic (2.37e-3)" "unprognostic (1.51e-2)" "unprognostic (4.80e-2)" "unprognostic (1.61e-1)" "unprognostic (1.50e-1)" "unprognostic (7.74e-3)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (2.32e-2)" "unprognostic (3.70e-2)" "unprognostic (1.36e-2)" "unprognostic (2.91e-1)" "unprognostic (2.16e-2)" "unprognostic (7.05e-2)" "unprognostic (1.63e-2)" "unprognostic (1.57e-2)" AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 62.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Breast lactating cells: 41.1;Early primary spermatocytes: 40.7;Extravillous trophoblasts: 113.0;Hepatocytes: 42.1;Prostatic glandular cells: 27.6" "Cell type enhanced" "Detected in many" "Trophoblast cells: 113.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 48.9" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Hepatocytes: 45208791.0" "Tissue enriched" "Detected in some" "liver: 865652.1" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "Plasma membrane" Vesicles "HPA037502: " "unprognostic (1.25e-1)" "unprognostic (2.12e-1)" "unprognostic (3.05e-1)" "unprognostic (2.15e-1)" "unprognostic (1.08e-2)" "unprognostic (3.09e-2)" "unprognostic (9.04e-2)" "unprognostic (1.27e-2)" "unprognostic (1.40e-1)" "unprognostic (2.72e-1)" "unprognostic (2.09e-2)" "unprognostic (7.29e-2)" "unprognostic (3.90e-3)" "unprognostic (1.43e-1)" "unprognostic (2.59e-2)" "unprognostic (1.47e-1)" "unprognostic (5.98e-2)" "unprognostic (1.22e-1)" "unprognostic (1.80e-1)" "unprognostic (6.90e-2)" "unprognostic (3.54e-1)" "unprognostic (1.98e-2)" "unprognostic (4.74e-3)" "unprognostic (2.58e-1)" "unprognostic (3.01e-3)" "unprognostic (2.20e-1)" "unprognostic (1.61e-1)" "unprognostic (3.87e-2)" "unprognostic (1.42e-1)" "unprognostic (5.27e-3)" "unprognostic (1.15e-1)" AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 83.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 20821429.6;Microglia and Neuropil: 28775099.0" "Tissue enriched" "Detected in many" "cerebral cortex: 80716658.0" "HPA017931, HPA020289" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" No No "Cluster 11: T-cells - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 28 "Plasma membrane" "Vesicles, Cytosol" "HPA017931: , HPA020289: " "unprognostic (1.64e-1)" "unprognostic (2.95e-3)" "unprognostic (1.48e-1)" "unprognostic (2.32e-1)" "unprognostic (2.02e-1)" "unprognostic (2.48e-3)" "unprognostic (1.07e-1)" "unprognostic (1.15e-1)" "unprognostic (4.66e-2)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (6.46e-3)" "unprognostic (7.86e-2)" "unprognostic (5.57e-2)" "unprognostic (2.42e-2)" "unprognostic (8.05e-2)" "unprognostic (2.48e-1)" "unprognostic (1.53e-2)" "unprognostic (2.27e-1)" "unprognostic (9.91e-2)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.43e-3)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (1.14e-1)" "unprognostic (6.14e-3)" "unprognostic (1.30e-2)" "unprognostic (5.20e-1)" "unprognostic (9.10e-2)" "unprognostic (1.11e-1)" "unprognostic (8.85e-3)" "unprognostic (6.12e-2)" AAMP ENSG00000127837 "Angio associated migratory cell protein" Q13685 2 218264129-218270178 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 190.5;Syncytiotrophoblasts: 240.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in many" "skin: 7889332.1" "CAB017717, HPA031868" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Cytosol" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 15: Non-specific - Protein processing" 23 Microtubules "Plasma membrane, Cytokinetic bridge, Primary cilium, Primary cilium tip, Cytosol" "CAB017717: , HPA031868: " "unprognostic (9.46e-2)" "unprognostic (7.23e-2)" "unprognostic (1.01e-1)" "unprognostic (4.68e-1)" "unprognostic (4.95e-2)" "unprognostic (1.07e-1)" "unprognostic (3.88e-3)" "unprognostic (6.15e-2)" "unprognostic (3.67e-2)" "unprognostic (1.25e-3)" "potential prognostic favorable (1.15e-7)" "unprognostic (5.58e-3)" "potential prognostic unfavorable (7.10e-4)" "validated prognostic unfavorable (4.27e-7)" "validated prognostic unfavorable (9.15e-8)" "unprognostic (8.83e-3)" "unprognostic (1.26e-1)" "unprognostic (8.16e-2)" "unprognostic (1.12e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" "unprognostic (9.14e-2)" "unprognostic (1.69e-1)" "unprognostic (5.30e-1)" "unprognostic (9.79e-2)" "unprognostic (2.08e-1)" "unprognostic (8.84e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (3.53e-2)" AARS1 "AARS, AlaRS, CMT2N" ENSG00000090861 "Alanyl-tRNA synthetase 1" P49588 16 70251983-70289707 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Epilepsy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB034261, HPA040870, HPA044223" Supported Supported Cytosol NA NA 930000 "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 65: Non-specific - Cell growth & division" 5 Cytosol "CAB034261: , HPA040870: , HPA044223: " "unprognostic (2.04e-3)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (3.62e-2)" "unprognostic (2.46e-1)" "unprognostic (6.65e-3)" "unprognostic (1.10e-1)" "unprognostic (3.71e-2)" "unprognostic (2.16e-2)" "unprognostic (2.48e-1)" "potential prognostic favorable (9.29e-6)" "unprognostic (9.49e-2)" "unprognostic (1.20e-1)" "unprognostic (9.40e-3)" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (7.71e-2)" "unprognostic (1.49e-1)" "unprognostic (1.57e-1)" "unprognostic (3.64e-1)" "unprognostic (1.63e-1)" "unprognostic (7.35e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (6.24e-2)" "unprognostic (4.67e-2)" "unprognostic (4.11e-2)" AASS "LKRSDH, LORSDH" ENSG00000008311 "Aminoadipate-semialdehyde synthase" Q9UDR5 7 122064583-122144308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 251.3;Hepatocytes: 392.2;Ovarian stromal cells: 272.8;Schwann cells: 296.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 392.2" "Cell type enhanced" "Detected in all" "Bergmann glia: 263.2;committed oligodendrocyte precursor: 267.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 34.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 186940877.8" "Tissue enriched" "Detected in many" "liver: 202640255.5" "HPA020637, HPA020728, HPA020734" Enhanced Approved Nucleoplasm,Vesicles,Mitochondria Yes No 20000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 1 Mitochondria "Nucleoplasm, Vesicles" "HPA020637: , HPA020728: , HPA020734: " "unprognostic (7.78e-2)" "unprognostic (4.81e-2)" "unprognostic (3.83e-2)" "unprognostic (3.25e-3)" "unprognostic (4.35e-2)" "unprognostic (7.18e-3)" "unprognostic (1.98e-2)" "unprognostic (8.49e-2)" "unprognostic (1.31e-1)" "unprognostic (2.73e-1)" "unprognostic (6.70e-2)" "potential prognostic favorable (9.30e-5)" "unprognostic (4.69e-2)" "potential prognostic favorable (7.41e-4)" "unprognostic (2.37e-3)" "unprognostic (1.25e-1)" "unprognostic (5.41e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (7.28e-4)" "unprognostic (2.27e-1)" "unprognostic (1.75e-1)" "unprognostic (3.23e-1)" "unprognostic (7.42e-3)" "unprognostic (2.04e-1)" "unprognostic (8.03e-2)" "unprognostic (1.62e-1)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (7.41e-2)" "unprognostic (6.34e-2)" "unprognostic (1.04e-1)" ABAT "GABA-T, GABAT" ENSG00000183044 "4-aminobutyrate aminotransferase" P80404 16 8674596-8784575 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Neurotransmitter degradation" "Aminotransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 128.7;kidney: 124.5;liver: 323.2;pancreas: 130.4" "Cell type enhanced" "Detected in many" "Corticotrophs: 152.3;Ependymal cells: 173.2;Hepatocytes: 350.3;Retinal amacrine cells: 154.6;Somatotrophs: 227.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 350.3;Pituitary endocrine cells: 227.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 88.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Exocrine glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 950686661.8;Pancreas epithelial cells: 1242415636.3;Pancreatic islets: 961558257.8;Proximal tubules: 899525487.9" "Group enriched" "Detected in many" "liver: 381503238.6;pancreas: 568582083.0" "HPA041528, HPA041690" Enhanced Supported Supported Mitochondria No No 2600000 "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 6 Mitochondria "HPA041528: , HPA041690: " "unprognostic (5.62e-2)" "unprognostic (1.01e-1)" "unprognostic (2.16e-2)" "unprognostic (1.67e-1)" "unprognostic (1.18e-1)" "unprognostic (5.31e-3)" "unprognostic (3.90e-1)" "unprognostic (1.09e-1)" "unprognostic (3.66e-1)" "unprognostic (3.07e-1)" "potential prognostic favorable (5.11e-8)" "unprognostic (4.54e-2)" "potential prognostic favorable (2.14e-5)" "potential prognostic favorable (5.42e-4)" "unprognostic (2.22e-3)" "potential prognostic favorable (6.68e-5)" "unprognostic (7.12e-3)" "unprognostic (1.97e-1)" "unprognostic (8.41e-2)" "unprognostic (1.58e-1)" "unprognostic (7.24e-2)" "unprognostic (2.97e-2)" "unprognostic (2.55e-1)" "unprognostic (1.83e-1)" "unprognostic (3.98e-2)" "unprognostic (2.52e-1)" "unprognostic (4.48e-1)" "unprognostic (5.41e-2)" "unprognostic (7.31e-2)" "unprognostic (2.78e-1)" "unprognostic (3.88e-2)" ABCA1 "ABC1, HDLDT1, TGD" ENSG00000165029 "ATP binding cassette subfamily A member 1" O95477 9 104781006-104928155 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Translocase "Atherosclerosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 432.4;Adrenal cortex cells: 862.8;Kupffer cells: 1038.2;Macrophages: 728.9;Mast cells: 577.9;monocytes: 680.4;Neutrophils: 1571.1;Smooth muscle cells: 486.4" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 862.8;Mononuclear phagocytes: 1038.2;Neutrophils: 1571.1" "Cell type enhanced" "Detected in all" "astrocyte: 485.5;fibroblast: 338.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "eosinophil: 13.1;neutrophil: 10.7" "Lineage enriched" "Detected in many" 8 "granulocytes: 13.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cell types: 3454019.6;Macrophages: 3865953.6" "Tissue enriched" "Detected in many" "blood vessel: 11228010.0" "CAB069889, HPA075201" Approved Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 "Plasma membrane" "Golgi apparatus" "CAB069889: , HPA075201: " "unprognostic (1.04e-2)" "unprognostic (2.61e-2)" "unprognostic (9.75e-2)" "unprognostic (2.19e-1)" "unprognostic (2.28e-1)" "unprognostic (8.23e-2)" "unprognostic (7.72e-2)" "unprognostic (8.66e-2)" "unprognostic (2.61e-1)" "unprognostic (1.87e-2)" "potential prognostic favorable (4.66e-4)" "unprognostic (6.71e-3)" "unprognostic (9.94e-3)" "unprognostic (7.19e-2)" "unprognostic (1.03e-1)" "unprognostic (2.68e-1)" "unprognostic (8.55e-3)" "unprognostic (1.50e-1)" "unprognostic (1.65e-1)" "unprognostic (4.09e-3)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (3.06e-1)" "unprognostic (5.37e-2)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.36e-2)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (7.46e-4)" "unprognostic (5.47e-2)" "unprognostic (2.50e-1)" "unprognostic (1.14e-1)" ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, p-170, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 96.1;intestine: 66.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 747.9;Colonocytes: 256.0;Enterocytes: 630.7;Hematopoietic stem cells: 640.0;Innate lymphoid cells: 147.7;NK-cells: 216.6;Thymocytes: 162.6;Vascular endothelial cells: 507.4" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 747.9;Endothelial cells: 507.4;Enterocytes: 630.7;Stem cells: 640.0" "Cell type enriched" "Detected in many" 23 "endothelial cell: 4738.8" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 35.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 26.0;liver cancer: 17.4" "Adrenal gland - Adrenal cortex cells, Prostate - Endothelial cells, Spleen - NK-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 76568885.3" "Tissue enhanced" "Detected in many" "intestine: 3491920.0" "CAB001716, HPA002199, HPA074614" Enhanced Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 70: DU4475 - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 10 "Plasma membrane" "CAB001716: , HPA002199: , HPA074614: " "unprognostic (5.03e-2)" "unprognostic (1.00e-1)" "unprognostic (8.89e-2)" "unprognostic (7.32e-3)" "unprognostic (8.80e-3)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.30e-8)" "unprognostic (9.76e-3)" "unprognostic (1.75e-1)" "unprognostic (1.06e-2)" "unprognostic (7.36e-2)" "unprognostic (2.74e-2)" "unprognostic (7.12e-2)" "unprognostic (3.61e-3)" "unprognostic (1.10e-1)" "unprognostic (3.54e-1)" "unprognostic (2.71e-2)" "unprognostic (1.33e-2)" "unprognostic (1.21e-1)" "unprognostic (8.59e-2)" "unprognostic (1.90e-1)" ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 16.8;Bergmann glia: 11.0;Brain excitatory neurons: 15.5;Brain inhibitory neurons: 18.9;Choroid plexus epithelial cells: 9.2;Ependymal cells: 12.7;Oligodendrocyte progenitor cells: 12.3;Oligodendrocytes: 8.7;Other brain neurons: 21.2" "Group enriched" "Detected in some" 11 "Ciliated cells: 12.7;Glial cells: 16.8;Neuronal cells: 21.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "skeletal muscle: 131095135.9" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol,Mid piece,Principal piece" "Intracellular and membrane" Transport NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol, Mid piece, Principal piece" "HPA046723: , HPA058011: " "unprognostic (4.36e-2)" "unprognostic (8.72e-3)" "unprognostic (1.88e-1)" "unprognostic (3.59e-2)" "unprognostic (4.22e-1)" "unprognostic (5.58e-3)" "unprognostic (5.85e-2)" "potential prognostic favorable (8.68e-4)" "unprognostic (2.17e-1)" "unprognostic (6.76e-2)" "potential prognostic favorable (1.37e-7)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (5.98e-4)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.65e-3)" "unprognostic (7.42e-2)" "unprognostic (2.09e-1)" "unprognostic (1.93e-2)" "unprognostic (3.19e-1)" "unprognostic (2.12e-2)" "unprognostic (6.36e-3)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (1.16e-1)" "unprognostic (7.91e-2)" "unprognostic (4.57e-1)" "unprognostic (9.85e-2)" "unprognostic (2.88e-1)" "unprognostic (9.88e-3)" "unprognostic (5.17e-2)" ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 58.1;liver: 49.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 816.2;Cholangiocytes: 415.9;Colonocytes: 358.2;Epididymal basal cells: 280.8;Foveolar cells: 490.2;Hepatocytes: 419.5;Pancreatic duct cells: 319.1;Papillary tip epithelial cells: 262.4;Platelets: 720.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 816.2;Gastric glandular cells: 490.2;Platelets: 720.9" "Group enriched" "Detected in many" 4 "astrocyte: 7.7;central nervous system macrophage: 15.2;deep-layer intratelencephalic: 12.3;ependymal cell: 11.5;leukocyte: 17.0;midbrain-derived inhibitory: 5.1;thalamic excitatory: 16.8;upper-layer intratelencephalic: 4.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Hepatocytes: 1957607.5;Keratinocytes: 1239271.7;Proximal tubules: 858873.8;T-cells: 1231682.6" "Tissue enhanced" "Detected in many" "kidney: 3615141.0;Stomach: 5693042.7" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane,Basal body" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" "Plasma membrane" "Basal body" "CAB037136: , HPA048483: " "unprognostic (1.23e-2)" "unprognostic (3.14e-3)" "unprognostic (1.03e-1)" "unprognostic (8.03e-2)" "unprognostic (5.45e-2)" "unprognostic (8.98e-2)" "unprognostic (5.60e-3)" "unprognostic (1.16e-2)" "unprognostic (1.86e-3)" "potential prognostic favorable (6.36e-4)" "unprognostic (5.22e-2)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.75e-1)" "unprognostic (1.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.48e-2)" "unprognostic (1.69e-1)" "unprognostic (8.19e-3)" "unprognostic (2.14e-1)" "unprognostic (1.05e-3)" "unprognostic (3.53e-1)" "unprognostic (3.24e-1)" "unprognostic (1.78e-1)" "unprognostic (2.13e-1)" "unprognostic (1.89e-2)" "unprognostic (1.37e-1)" "unprognostic (2.42e-1)" "unprognostic (6.76e-2)" ABCC8 "ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, TNDM2" ENSG00000006071 "ATP binding cassette subfamily C member 8" Q09428 11 17392498-17476894 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Receptor "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 22.2;pancreas: 13.3;pituitary gland: 23.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Astrocytes: 40.8;Brain excitatory neurons: 60.7;Brain inhibitory neurons: 36.6;Corticotrophs: 66.2;Endometrial stromal cells: 50.7;Gonadotrophs: 89.8;Neuroendocrine cells: 61.5;Oligodendrocyte progenitor cells: 65.8;Pancreatic islet cells: 264.2;Retinal bipolar cells: 75.3;Somatotrophs: 70.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 191.5;Neuronal cells: 75.3;Pancreatic islet cells: 264.2;Pituitary endocrine cells: 89.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Pancreatic Adenocarcinoma (TCGA): 23.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 9 "thyroid cancer: 3.4" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Pancreatic islets: 16431930.3" "Tissue enriched" "Detected in some" "lymphoid tissue: 2434927.0" "CAB011451, HPA042318" Approved Approved "Nucleoli,Golgi apparatus,Cytosol,Principal piece" No NA "Cluster 70: Non-specific - Protein processing" "Cluster 24: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Nucleoli, Golgi apparatus" "Cytosol, Principal piece" "CAB011451: , HPA042318: " "unprognostic (2.97e-1)" "unprognostic (2.51e-2)" "unprognostic (3.41e-2)" "unprognostic (1.26e-2)" "unprognostic (1.79e-2)" "unprognostic (1.41e-2)" "unprognostic (1.62e-2)" "unprognostic (4.12e-2)" ABCE1 "OABP, RLI, RLI1, RNASEL1, RNASELI, RNS4I" ENSG00000164163 "ATP binding cassette subfamily E member 1" P61221 4 145098288-145129524 "Essential proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Translation regulation" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "CAB012476, HPA036846" Approved Enhanced Cytosol No No 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 75 Cytosol "CAB012476: , HPA036846: " "unprognostic (2.48e-1)" "unprognostic (2.26e-2)" "unprognostic (1.67e-1)" "unprognostic (2.69e-2)" "unprognostic (7.75e-3)" "unprognostic (7.16e-2)" "unprognostic (1.29e-1)" "unprognostic (7.70e-2)" "unprognostic (1.37e-2)" "unprognostic (1.27e-2)" "potential prognostic favorable (2.93e-5)" "unprognostic (7.08e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (3.74e-2)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (3.25e-1)" "unprognostic (1.33e-1)" "unprognostic (2.78e-2)" "unprognostic (4.44e-2)" "unprognostic (1.08e-3)" "unprognostic (1.89e-2)" "unprognostic (1.43e-2)" "unprognostic (3.17e-3)" "unprognostic (5.55e-2)" "unprognostic (9.38e-2)" "unprognostic (2.04e-1)" "unprognostic (3.84e-1)" "potential prognostic unfavorable (6.34e-4)" "unprognostic (1.19e-1)" ABHD10 FLJ11342 ENSG00000144827 "Abhydrolase domain containing 10, depalmitoylase" Q9NUJ1 3 111979010-111993368 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 74.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 150228561.3" "Tissue enhanced" "Detected in all" "kidney: 42755763.6" "HPA036991, HPA036992, HPA066081" Supported Approved Mitochondria No No 63000 "Cluster 32: Basophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 25 Mitochondria "HPA036991: , HPA036992: , HPA066081: " "unprognostic (1.65e-2)" "unprognostic (1.47e-1)" "unprognostic (5.19e-3)" "unprognostic (4.01e-1)" "unprognostic (4.93e-2)" "unprognostic (1.13e-1)" "unprognostic (5.74e-2)" "unprognostic (6.27e-2)" "unprognostic (1.17e-2)" "unprognostic (7.31e-2)" "potential prognostic favorable (1.05e-6)" "unprognostic (2.41e-1)" "unprognostic (1.05e-3)" "unprognostic (2.36e-2)" "unprognostic (1.30e-1)" "unprognostic (3.86e-2)" "unprognostic (1.34e-1)" "unprognostic (7.44e-2)" "unprognostic (1.67e-1)" "unprognostic (3.41e-1)" "unprognostic (3.24e-3)" "unprognostic (3.29e-1)" "unprognostic (7.62e-3)" "unprognostic (1.60e-1)" "unprognostic (1.39e-1)" "unprognostic (3.31e-1)" "unprognostic (1.31e-1)" "unprognostic (2.66e-2)" "unprognostic (3.03e-1)" "unprognostic (8.16e-3)" "unprognostic (2.20e-2)" ABHD14A "DKFZP564O243, DORZ1" ENSG00000248487 "Abhydrolase domain containing 14A" Q9BUJ0 3 51971426-51981196 "Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "Cardiomyocytes: 579.2" "Cell type enriched" "Detected in many" 9 "Myocytes: 579.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1195503.4;Glomeruli: 495921.7" "Not detected" "Not detected" "HPA038153, HPA056913" Approved Supported Vesicles NA NA 100000 "Cluster 11: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 15 Vesicles "HPA038153: , HPA056913: " "unprognostic (3.13e-3)" "unprognostic (5.39e-3)" "unprognostic (7.94e-3)" "unprognostic (5.99e-2)" "unprognostic (9.14e-2)" "unprognostic (1.37e-1)" "unprognostic (1.08e-1)" "unprognostic (9.65e-2)" "unprognostic (1.05e-1)" "unprognostic (4.58e-2)" "unprognostic (1.04e-1)" "unprognostic (4.04e-1)" "potential prognostic favorable (1.70e-7)" "unprognostic (3.79e-2)" "unprognostic (2.43e-2)" "unprognostic (1.04e-2)" "unprognostic (3.26e-1)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (9.09e-2)" "unprognostic (2.26e-1)" "unprognostic (1.54e-3)" "unprognostic (3.92e-2)" "unprognostic (2.18e-1)" "unprognostic (7.95e-2)" "unprognostic (1.11e-1)" "unprognostic (2.65e-1)" "unprognostic (6.55e-2)" "unprognostic (3.67e-1)" "unprognostic (6.10e-2)" "unprognostic (7.30e-2)" ABHD14A-ACY1 ENSG00000114786 "ABHD14A-ACY1 readthrough" 3 51974706-51989183 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 4.6;Enterocytes: 9.4;Epicardial cells: 4.5;Hepatic stellate cells: 6.5;Retinal amacrine cells: 5.0;Retinal bipolar cells: 4.4;Retinal horizontal cells: 8.0;Rod photoreceptor cells: 7.2" "Cell type enhanced" "Detected in many" "Enterocytes: 9.4;Neuronal cells: 8.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA036174, HPA036175, HPA038153, HPA071834" Approved Supported Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 35: Non-specific - DNA binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" Vesicles "HPA036174: , HPA036175: , HPA038153: , HPA071834: " "unprognostic (3.41e-2)" "unprognostic (4.19e-1)" "unprognostic (4.77e-2)" "unprognostic (8.32e-2)" "unprognostic (4.22e-1)" "unprognostic (2.94e-1)" ABHD18 "C4orf29, FLJ21106" ENSG00000164074 "Abhydrolase domain containing 18" Q0P651 4 127965306-128039953 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 735415.5" "Tissue enriched" "Detected in single" 28 "heart muscle: 2807.3" "HPA050168, HPA051676" Approved Approved "Nuclear membrane" "Intracellular and membrane" "No annotated function" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 55: Myocytes - Oxidative muscle function" 4 "Nuclear membrane" "HPA050168: , HPA051676: " "unprognostic (3.19e-2)" "unprognostic (9.55e-2)" "unprognostic (3.43e-2)" "unprognostic (8.83e-2)" "unprognostic (1.39e-1)" "unprognostic (6.64e-2)" "unprognostic (1.91e-1)" "unprognostic (1.53e-1)" "unprognostic (1.68e-3)" "unprognostic (5.37e-3)" "potential prognostic favorable (7.17e-4)" "unprognostic (3.01e-2)" "unprognostic (9.39e-2)" "unprognostic (1.93e-2)" "unprognostic (7.22e-2)" "unprognostic (1.16e-2)" "unprognostic (5.90e-2)" "unprognostic (1.38e-1)" "unprognostic (2.81e-1)" "unprognostic (4.59e-2)" "unprognostic (2.47e-2)" "unprognostic (6.10e-3)" "potential prognostic favorable (5.22e-5)" "unprognostic (2.61e-1)" "unprognostic (9.02e-2)" "unprognostic (2.91e-2)" "unprognostic (1.72e-1)" "unprognostic (1.65e-2)" "unprognostic (2.26e-1)" ABHD2 LABH2 ENSG00000140526 "Abhydrolase domain containing 2, acylglycerol lipase" P08910 15 89087459-89202355 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 128.7" "Cell type enhanced" "Detected in many" "Foveolar cells: 670.3;Hepatocytes: 691.6;Late spermatids: 805.5;Neutrophils: 907.5;Oligodendrocyte progenitor cells: 642.0" "Cell type enhanced" "Detected in all" "Neutrophils: 907.5" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 620.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 70.0;neutrophil: 52.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1208 "Hepatocytes: 90598.7;Pancreas epithelial cells: 150980.4" "Group enriched" "Detected in some" 7903 "liver: 1211241.9;pancreas: 369344.0" HPA005999 Approved Approved "Nucleoplasm,Cytosol,Connecting piece,Flagellar centriole" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Cytosol, Flagellar centriole" "Nucleoplasm, Connecting piece" "HPA005999: " "unprognostic (1.20e-1)" "unprognostic (1.27e-1)" "unprognostic (2.72e-1)" "unprognostic (5.46e-2)" "unprognostic (4.66e-2)" "unprognostic (7.51e-3)" "unprognostic (9.35e-2)" "unprognostic (1.69e-2)" "unprognostic (5.28e-2)" "unprognostic (3.15e-2)" "validated prognostic favorable (1.47e-6)" "validated prognostic favorable (3.89e-4)" "unprognostic (3.05e-2)" "unprognostic (1.64e-1)" "unprognostic (2.72e-2)" "unprognostic (4.34e-2)" "unprognostic (2.58e-1)" "unprognostic (5.96e-2)" "unprognostic (5.43e-2)" "unprognostic (3.77e-3)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.23e-3)" "unprognostic (1.12e-1)" "unprognostic (5.67e-2)" "unprognostic (1.85e-1)" "unprognostic (3.26e-1)" "unprognostic (3.00e-1)" "unprognostic (1.82e-1)" "unprognostic (4.45e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-1)" ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 61.7" "Cell type enhanced" "Detected in many" "Colonocytes: 425.4;Endometrial luminal cells: 513.7;Epididymal clear cells: 518.5;Esophageal apical cells: 462.3;Myonuclei: 655.4;Neutrophils: 487.7;Pancreatic duct cells: 464.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 431681.5;Large ducts: 252774.6;Macrophages: 179470.2;Neutrophils: 145651.0;T-cells: 194817.1" "Group enriched" "Detected in some" "liver: 77720.5;lymphoid tissue: 124681.2" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 24: Neutrophils - Innate immunity signal integration" 6 "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: " "unprognostic (1.90e-1)" "unprognostic (1.49e-1)" "unprognostic (2.02e-1)" "unprognostic (6.95e-2)" "unprognostic (2.36e-2)" "unprognostic (1.26e-2)" "unprognostic (6.97e-2)" "unprognostic (1.82e-1)" "unprognostic (8.59e-3)" "unprognostic (4.94e-2)" "unprognostic (2.27e-2)" "unprognostic (4.94e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (1.27e-3)" "unprognostic (2.17e-1)" "unprognostic (2.10e-1)" "unprognostic (1.30e-1)" "unprognostic (3.32e-2)" "unprognostic (9.29e-2)" "unprognostic (2.24e-1)" "unprognostic (2.63e-1)" "unprognostic (9.31e-2)" "unprognostic (7.27e-2)" "unprognostic (6.80e-3)" "unprognostic (1.26e-1)" "unprognostic (1.94e-1)" "unprognostic (8.11e-2)" "potential prognostic unfavorable (4.96e-4)" ABHD5 "CGI-58, NCIE2" ENSG00000011198 "Abhydrolase domain containing 5, lysophosphatidic acid acyltransferase" Q8WTS1 3 43690108-43734371 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Cataract, Deafness, Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 763.3;Neutrophil progenitors: 1162.9;Neutrophils: 2098.3;Syncytiotrophoblasts: 685.1" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 763.3;Neutrophils: 2098.3;Trophoblast cells: 685.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 68.2;neutrophil: 42.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 68.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 1511850.1;Neutrophils: 2027351.3" "Tissue enhanced" "Detected in many" "skeletal muscle: 1719464.4" "CAB020685, HPA035851, HPA035852" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 58: Skin - Keratinization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 20 "Vesicles, Cytosol" Nucleoplasm "CAB020685: , HPA035851: , HPA035852: " "unprognostic (3.68e-3)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (3.41e-1)" "unprognostic (1.16e-2)" "unprognostic (1.47e-1)" "unprognostic (2.86e-2)" "unprognostic (9.16e-3)" "unprognostic (1.10e-1)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (2.68e-1)" "unprognostic (2.17e-3)" "unprognostic (4.52e-2)" "unprognostic (1.35e-1)" "unprognostic (4.19e-2)" "unprognostic (1.89e-1)" "unprognostic (2.11e-1)" "unprognostic (5.55e-2)" "unprognostic (3.13e-3)" "unprognostic (1.41e-1)" "unprognostic (2.93e-2)" "unprognostic (1.10e-1)" "unprognostic (1.73e-2)" "unprognostic (1.99e-1)" "unprognostic (2.80e-1)" "unprognostic (7.49e-2)" "unprognostic (5.88e-2)" "unprognostic (2.14e-1)" "unprognostic (1.92e-2)" "unprognostic (1.43e-1)" ABHD6 ENSG00000163686 "Abhydrolase domain containing 6, acylglycerol lipase" Q9BV23 3 58237532-58295693 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7" "Cell type enhanced" "Detected in many" "Corticotrophs: 152.0;Enterocytes: 136.7;Hepatocytes: 93.1;Lactotrophs: 85.3;Oligodendrocytes: 117.7;Proximal tubule cells: 158.7" "Cell type enhanced" "Detected in many" "Enterocytes: 136.7;Pituitary endocrine cells: 152.0;Renal nephron cells: 158.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bone cancer: 53.5" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 14928327.8" "Tissue enhanced" "Detected in many" "lung: 19708326.6" "HPA017283, HPA073225" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 88: Proximal tubular cells - Transmembrane transport" 6 Vesicles Nucleoplasm "HPA017283: , HPA073225: " "unprognostic (9.31e-3)" "unprognostic (1.16e-1)" "unprognostic (2.25e-2)" "unprognostic (1.78e-1)" "unprognostic (2.25e-3)" "unprognostic (3.46e-2)" "unprognostic (2.22e-2)" "potential prognostic favorable (2.16e-5)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "validated prognostic favorable (1.72e-8)" "validated prognostic favorable (4.84e-6)" "potential prognostic favorable (3.08e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "unprognostic (4.72e-3)" "unprognostic (2.72e-3)" "unprognostic (2.30e-1)" "unprognostic (1.86e-1)" "unprognostic (3.44e-3)" "unprognostic (7.03e-2)" "unprognostic (3.74e-3)" "unprognostic (1.66e-2)" "unprognostic (1.09e-1)" "unprognostic (4.80e-2)" "unprognostic (1.37e-1)" "unprognostic (7.26e-2)" "unprognostic (5.29e-2)" "unprognostic (2.24e-2)" "unprognostic (3.70e-1)" "unprognostic (1.30e-1)" ABITRAM "C9orf6, CG-8, FAM206A, FLJ20457, Simiate" ENSG00000119328 "Actin binding transcription modulator" Q9NX38 9 108934400-108950744 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 127.4;Respiratory ciliated cells: 63.0" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 127.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 81 "Granulosa cells: 8077.0" "Not detected" "Not detected" "HPA035917, HPA035918" Uncertain Approved "Nucleoplasm,Kinetochore,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Cytosol" Yes No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 9 "Nucleoplasm, Cytosol" "Kinetochore, Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip" "HPA035917: , HPA035918: " "unprognostic (1.39e-1)" "unprognostic (1.27e-2)" "unprognostic (6.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.58e-2)" "unprognostic (3.17e-1)" "unprognostic (3.29e-3)" "unprognostic (4.38e-3)" "unprognostic (1.11e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (2.88e-1)" "unprognostic (6.05e-2)" "potential prognostic unfavorable (2.46e-4)" "unprognostic (2.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (1.64e-1)" "unprognostic (2.08e-1)" "unprognostic (1.24e-1)" "unprognostic (5.72e-2)" "unprognostic (8.41e-2)" "unprognostic (6.50e-2)" "unprognostic (7.74e-2)" "unprognostic (2.31e-2)" "unprognostic (3.55e-1)" "unprognostic (9.01e-2)" "unprognostic (2.90e-1)" "unprognostic (5.73e-2)" "unprognostic (1.50e-2)" ABL1 "ABL, c-ABL, JTK7, p150" ENSG00000097007 "ABL proto-oncogene 1, non-receptor tyrosine kinase" P00519 9 130713043-130887675 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Autophagy, Cell adhesion, DNA damage, DNA repair, Endocytosis" "DNA-binding, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 1600002.7;Macrophages: 750407.5" "Tissue enriched" "Detected in many" "salivary gland: 1222526.6" "CAB002686, HPA027251, HPA027280, HPA028409" Supported Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 162 Nucleoplasm "Nuclear bodies" "CAB002686: , HPA027251: , HPA027280: , HPA028409: " "unprognostic (1.53e-1)" "unprognostic (2.66e-2)" "unprognostic (4.09e-1)" "unprognostic (1.27e-2)" "unprognostic (1.56e-1)" "unprognostic (1.40e-2)" "unprognostic (6.41e-2)" "unprognostic (3.49e-2)" "unprognostic (2.96e-1)" "unprognostic (2.22e-1)" "potential prognostic favorable (2.76e-4)" "unprognostic (7.92e-3)" "unprognostic (4.17e-1)" "unprognostic (7.37e-3)" "unprognostic (5.27e-2)" "unprognostic (2.14e-2)" "unprognostic (7.30e-2)" "unprognostic (1.14e-2)" "unprognostic (3.64e-3)" "unprognostic (1.42e-2)" "unprognostic (2.99e-3)" "unprognostic (9.06e-2)" "unprognostic (3.81e-1)" "unprognostic (1.44e-1)" "unprognostic (2.60e-2)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (7.66e-2)" "unprognostic (3.38e-1)" "unprognostic (9.73e-2)" "unprognostic (3.41e-2)" ABRAXAS2 "ABRO1, Em:AC068896.4, FAM175B, KIAA0157" ENSG00000165660 "Abraxas 2, BRISC complex subunit" Q15018 10 124801819-124836667 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA037591, HPA037592, HPA074089" Approved Supported "Primary cilium transition zone,Basal body,Cytosol" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 29 Cytosol "Primary cilium transition zone, Basal body" "HPA037591: , HPA037592: , HPA074089: " "unprognostic (1.92e-1)" "unprognostic (1.18e-1)" "unprognostic (5.49e-2)" "unprognostic (1.52e-1)" "unprognostic (3.59e-2)" "unprognostic (4.94e-1)" "potential prognostic favorable (4.69e-4)" "unprognostic (2.54e-1)" "unprognostic (2.74e-3)" "potential prognostic favorable (7.55e-7)" "unprognostic (1.61e-2)" "unprognostic (1.45e-1)" "unprognostic (2.75e-2)" "unprognostic (1.43e-1)" "unprognostic (5.23e-2)" "unprognostic (7.49e-2)" "unprognostic (4.46e-1)" "unprognostic (7.61e-2)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "unprognostic (2.95e-1)" "unprognostic (1.35e-3)" "unprognostic (1.54e-1)" "unprognostic (1.80e-1)" "unprognostic (2.39e-1)" "unprognostic (2.13e-1)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (3.57e-1)" ABTB2 "ABTB2A, BTBD22, DKFZP586C1619" ENSG00000166016 "Ankyrin repeat and BTB domain containing 2" Q8N961 11 34150987-34358010 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.6" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 375.8;Endometrial glandular cells: 435.1;Renal collecting duct principal cells: 1082.9;Renal connecting tubule cells: 1049.1;Syncytiotrophoblasts: 504.1;Urothelial cells: 432.4" "Cell type enhanced" "Detected in many" "Ductal cells: 1082.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 243.0;committed oligodendrocyte precursor: 494.3;oligodendrocyte: 299.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 26.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "eosinophil: 5.0;plasmacytoid DC: 1.6" "Group enriched" "Detected in many" 14 "dendritic cells: 1.6;granulocytes: 5.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 809161.3;Distal tubules: 1165317.9;Large ducts: 1622631.2" "Not detected" "Not detected" "HPA020065, HPA030699" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 5 Nucleoplasm Vesicles "HPA020065: , HPA030699: " "unprognostic (2.89e-2)" "unprognostic (1.09e-1)" "unprognostic (3.11e-1)" "unprognostic (1.90e-3)" "unprognostic (2.50e-1)" "unprognostic (1.51e-3)" "unprognostic (2.06e-1)" "unprognostic (4.19e-1)" "unprognostic (1.00e-1)" "unprognostic (1.31e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (2.14e-1)" "unprognostic (1.67e-1)" "unprognostic (4.82e-2)" "unprognostic (2.11e-3)" "unprognostic (1.74e-3)" "unprognostic (1.72e-1)" "unprognostic (8.77e-2)" "unprognostic (3.67e-2)" "unprognostic (1.54e-1)" "unprognostic (4.15e-3)" "unprognostic (9.10e-2)" "unprognostic (3.54e-1)" "unprognostic (6.86e-2)" "unprognostic (8.49e-2)" "unprognostic (2.27e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (8.47e-2)" "unprognostic (2.89e-1)" ACAA2 DSAEC ENSG00000167315 "Acetyl-CoA acyltransferase 2" P42765 18 49782164-49813953 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 945.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 248.6;Colonocytes: 297.7;Enteric transient amplifying cells: 170.3;Enterocytes: 199.2;Hepatocytes: 854.3;Late spermatids: 265.7" "Cell type enhanced" "Detected in all" "Enterocytes: 297.7;Hepatocytes: 854.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 1772071826.8;Proximal tubules: 1359891728.0" "Group enriched" "Detected in all" "heart muscle: 399562124.5;kidney: 372703412.3;liver: 1071219273.9" HPA042303 Approved Supported "Mitochondria,Basal body,Cytosol" NA NA 5100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 36 Mitochondria "Basal body, Cytosol" "HPA042303: " "unprognostic (2.83e-1)" "unprognostic (1.82e-1)" "unprognostic (8.20e-2)" "unprognostic (4.08e-2)" "unprognostic (2.75e-2)" "unprognostic (5.45e-3)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "validated prognostic favorable (7.17e-11)" "validated prognostic favorable (1.98e-4)" "potential prognostic favorable (4.06e-5)" "unprognostic (3.29e-2)" "unprognostic (3.30e-2)" "unprognostic (7.73e-2)" "unprognostic (2.87e-1)" "unprognostic (9.18e-2)" "unprognostic (9.88e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (9.03e-2)" "unprognostic (2.17e-1)" "unprognostic (1.41e-1)" "unprognostic (4.10e-2)" "unprognostic (1.67e-1)" "unprognostic (2.20e-1)" "unprognostic (1.73e-1)" "unprognostic (2.50e-1)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (6.52e-4)" ACAD9 "MGC14452, NPD002" ENSG00000177646 "Acyl-CoA dehydrogenase family member 9" Q9H845 3 128879596-128924003 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in all" "skin: 235802717.5" "HPA037716, HPA046720" Supported Enhanced Mitochondria No No 8900 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 51: Secretory epithelial cells - Mixed function" 60 Mitochondria "HPA037716: , HPA046720: " "unprognostic (1.07e-1)" "unprognostic (4.12e-2)" "unprognostic (2.16e-1)" "unprognostic (3.37e-1)" "unprognostic (3.85e-3)" "unprognostic (8.34e-2)" "unprognostic (5.75e-2)" "unprognostic (4.34e-2)" "unprognostic (2.36e-1)" "unprognostic (9.18e-2)" "potential prognostic favorable (8.34e-7)" "unprognostic (7.70e-2)" "unprognostic (1.65e-2)" "unprognostic (4.65e-3)" "unprognostic (1.88e-2)" "unprognostic (1.25e-2)" "unprognostic (2.76e-1)" "unprognostic (4.51e-1)" "unprognostic (1.38e-1)" "unprognostic (5.58e-2)" "unprognostic (3.39e-1)" "unprognostic (4.91e-3)" "unprognostic (3.05e-3)" "unprognostic (1.22e-1)" "unprognostic (1.98e-1)" "unprognostic (4.60e-2)" "unprognostic (4.90e-2)" "unprognostic (1.76e-2)" "unprognostic (2.00e-1)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" ACADM "ACAD1, MCAD, MCADH" ENSG00000117054 "Acyl-CoA dehydrogenase medium chain" P11310 1 75724431-75787575 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 343.6;skeletal muscle: 357.2;tongue: 445.9" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 740.0;Hepatocytes: 338.0;Parietal cells: 316.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 740.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells, Stomach - Parietal cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 474371028.0;Proximal tubules: 586759865.9" "Tissue enhanced" "Detected in all" "heart muscle: 401018888.9" "HPA006198, HPA026542" Enhanced Supported "Mitochondria,Perinuclear theca,Calyx,Principal piece" NA NA 480000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 84: Apical squamous epithelium - Cornification" 12 Mitochondria "Perinuclear theca, Calyx, Principal piece" "HPA006198: , HPA026542: " "unprognostic (6.45e-2)" "unprognostic (6.04e-2)" "unprognostic (2.18e-1)" "unprognostic (1.44e-1)" "unprognostic (7.57e-3)" "unprognostic (2.73e-3)" "unprognostic (8.00e-2)" "unprognostic (2.55e-1)" "unprognostic (2.07e-2)" "unprognostic (2.75e-2)" "validated prognostic favorable (4.28e-13)" "validated prognostic favorable (1.48e-4)" "unprognostic (1.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.51e-2)" "unprognostic (1.10e-1)" "unprognostic (3.13e-2)" "unprognostic (7.77e-2)" "unprognostic (1.14e-1)" "unprognostic (3.22e-2)" "unprognostic (7.49e-2)" "unprognostic (2.40e-1)" "unprognostic (1.35e-2)" "unprognostic (2.68e-1)" "unprognostic (7.10e-3)" "unprognostic (1.03e-1)" "unprognostic (1.13e-1)" "unprognostic (1.10e-1)" "unprognostic (4.55e-2)" "unprognostic (1.80e-1)" "unprognostic (2.72e-2)" ACADS "ACAD3, SCAD" ENSG00000122971 "Acyl-CoA dehydrogenase short chain" P16219 12 120725774-120740008 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 253.5;skeletal muscle: 160.6" "Cell type enhanced" "Detected in many" "Colonocytes: 276.5;Cytotrophoblasts: 100.9;Enteric stem cells: 141.8;Enteric transient amplifying cells: 204.0;Enterocytes: 385.9;Hepatocytes: 241.3;Paneth cells: 112.2" "Cell type enhanced" "Detected in many" "Enterocytes: 385.9;Hepatocytes: 241.3;Proliferating cells: 204.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 135.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 305921834.7" "Tissue enhanced" "Detected in all" "liver: 187112414.7" "HPA004799, CAB019284, HPA022271" Enhanced Supported "Nucleoplasm,Centrosome,Mitochondria,Mid piece,Principal piece,End piece" NA NA 14000 "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Mitochondria "Nucleoplasm, Centrosome, Mid piece, Principal piece, End piece" "CAB019284: , HPA004799: , HPA022271: " "unprognostic (3.88e-1)" "unprognostic (1.25e-1)" "unprognostic (1.17e-1)" "unprognostic (1.09e-2)" "unprognostic (1.28e-2)" "unprognostic (2.31e-1)" "validated prognostic unfavorable (1.52e-4)" "validated prognostic unfavorable (5.91e-5)" "unprognostic (1.18e-2)" "unprognostic (2.61e-1)" "potential prognostic favorable (5.62e-5)" "unprognostic (4.05e-2)" "potential prognostic favorable (1.44e-4)" "potential prognostic favorable (6.09e-4)" "unprognostic (1.31e-1)" "unprognostic (5.03e-3)" "unprognostic (7.39e-2)" "unprognostic (7.12e-2)" "unprognostic (1.73e-1)" "unprognostic (7.49e-2)" "unprognostic (3.05e-1)" "unprognostic (1.17e-1)" "unprognostic (1.24e-3)" "unprognostic (4.68e-1)" "unprognostic (4.56e-2)" "unprognostic (3.42e-2)" "unprognostic (6.56e-2)" "unprognostic (4.18e-3)" "unprognostic (1.61e-1)" "unprognostic (6.54e-2)" "potential prognostic favorable (4.58e-5)" ACADSB "ACAD7, SBCAD" ENSG00000196177 "Acyl-CoA dehydrogenase short/branched chain" P45954 10 123008979-123058290 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 336.7" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 655.8" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 655.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 44.3" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 714879749.1;Proximal tubules: 383813128.3" "Tissue enriched" "Detected in all" "liver: 292954924.4" "HPA041458, HPA063555" Enhanced Supported Mitochondria NA NA 50000 "Cluster 39: T-cells - T-cell receptor" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 Mitochondria "HPA041458: , HPA063555: " "unprognostic (9.00e-2)" "unprognostic (5.74e-2)" "unprognostic (4.01e-2)" "unprognostic (6.07e-2)" "potential prognostic favorable (5.02e-4)" "unprognostic (1.23e-2)" "unprognostic (2.14e-1)" "unprognostic (5.44e-2)" "unprognostic (2.93e-2)" "unprognostic (1.04e-1)" "validated prognostic favorable (4.41e-11)" "validated prognostic favorable (9.15e-5)" "unprognostic (3.96e-2)" "unprognostic (3.85e-2)" "unprognostic (5.06e-2)" "unprognostic (2.34e-3)" "unprognostic (8.67e-2)" "unprognostic (1.33e-1)" "unprognostic (4.84e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (9.66e-5)" "unprognostic (2.75e-2)" "unprognostic (3.12e-2)" "unprognostic (7.86e-2)" "unprognostic (1.12e-2)" "unprognostic (2.29e-1)" "unprognostic (1.15e-1)" "unprognostic (2.06e-1)" "unprognostic (1.25e-1)" "unprognostic (4.52e-3)" "unprognostic (1.20e-1)" ACADVL "ACAD6, LCACD, VLCAD" ENSG00000072778 "Acyl-CoA dehydrogenase very long chain" P49748 17 7217125-7225266 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 798.8;Cytotrophoblasts: 557.4;Esophageal apical cells: 784.3;Syncytiotrophoblasts: 828.1" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 784.3;Myocytes: 798.8;Trophoblast cells: 828.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1643473487.4" "Tissue enhanced" "Detected in all" "heart muscle: 681100626.8" "HPA019006, HPA020595" Enhanced Supported Nucleoplasm,Nucleoli,Mitochondria NA NA 69000 "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 42: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 Mitochondria "Nucleoplasm, Nucleoli" "HPA019006: , HPA020595: " "unprognostic (8.19e-2)" "unprognostic (1.63e-1)" "unprognostic (7.29e-2)" "unprognostic (1.87e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-2)" "unprognostic (1.27e-2)" "unprognostic (1.56e-1)" "unprognostic (3.28e-1)" "potential prognostic favorable (7.42e-8)" "unprognostic (1.67e-2)" "unprognostic (9.27e-3)" "unprognostic (4.77e-3)" "potential prognostic favorable (6.89e-4)" "unprognostic (1.01e-1)" "unprognostic (8.89e-3)" "unprognostic (2.44e-1)" "unprognostic (1.83e-1)" "unprognostic (1.60e-1)" "unprognostic (4.16e-2)" "unprognostic (4.09e-2)" "unprognostic (1.85e-3)" "unprognostic (1.32e-1)" "unprognostic (1.48e-1)" "unprognostic (6.82e-2)" "unprognostic (2.14e-1)" "unprognostic (1.68e-2)" "unprognostic (1.43e-1)" "unprognostic (6.88e-2)" "unprognostic (1.71e-1)" ACAT1 "ACAT, THIL" ENSG00000075239 "Acetyl-CoA acetyltransferase 1" P24752 11 108116695-108147603 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 580.7;liver: 905.7" "Cell type enhanced" "Detected in many" "Early spermatids: 444.2;Hepatocytes: 804.5;Late primary spermatocytes: 403.6;Parietal cells: 484.4" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 484.4;Hepatocytes: 804.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 542.4" "Region enriched" "Detected in all" 4 "choroid plexus: 124.0" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubules: 1887354087.6" "Low tissue specificity" "Detected in all" "HPA004428, HPA007569" Enhanced Enhanced Mitochondria NA NA 730000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 15 Mitochondria "HPA004428: , HPA007569: " "unprognostic (9.86e-2)" "unprognostic (2.31e-2)" "unprognostic (3.32e-1)" "unprognostic (1.01e-1)" "unprognostic (8.32e-2)" "unprognostic (2.05e-2)" "unprognostic (4.08e-1)" "unprognostic (3.01e-2)" "unprognostic (4.54e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.55e-11)" "unprognostic (9.23e-3)" "potential prognostic favorable (3.02e-5)" "potential prognostic favorable (4.27e-4)" "unprognostic (1.04e-3)" "unprognostic (5.77e-3)" "unprognostic (3.21e-1)" "unprognostic (1.73e-1)" "unprognostic (2.84e-1)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (3.18e-2)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (2.91e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-2)" "unprognostic (1.67e-1)" "unprognostic (2.78e-1)" "unprognostic (4.64e-2)" "unprognostic (6.88e-2)" ACAT2 ENSG00000120437 "Acetyl-CoA acetyltransferase 2" Q9BWD1 6 159762045-159779112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 216.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 213.9;Breast lactating cells: 235.5;Early spermatids: 247.6;Esophageal apical cells: 197.6;Esophageal basal cells: 184.4;Esophageal suprabasal cells: 223.5;Late spermatids: 190.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 87053865.2" "Group enriched" "Detected in all" "cerebral cortex: 74519134.9;liver: 248922512.6" "CAB021106, HPA025736, HPA025765, HPA025811" Enhanced Approved Nucleoplasm,Cytosol NA NA 2500000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 3 Cytosol Nucleoplasm "CAB021106: , HPA025736: , HPA025765: , HPA025811: " "unprognostic (5.58e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (2.34e-5)" "unprognostic (1.95e-2)" "unprognostic (1.50e-2)" "unprognostic (1.54e-1)" "unprognostic (7.76e-2)" "unprognostic (1.59e-1)" "unprognostic (3.50e-1)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (3.83e-2)" "unprognostic (9.94e-2)" "unprognostic (9.83e-2)" "unprognostic (1.06e-1)" "unprognostic (3.24e-3)" "unprognostic (2.28e-3)" "unprognostic (1.31e-1)" "unprognostic (6.50e-2)" "unprognostic (3.35e-3)" "unprognostic (1.77e-1)" "unprognostic (3.07e-1)" "unprognostic (6.19e-2)" "unprognostic (5.95e-2)" "unprognostic (2.47e-1)" "unprognostic (9.42e-2)" "unprognostic (1.38e-1)" "unprognostic (8.72e-2)" "unprognostic (2.20e-1)" "unprognostic (4.77e-2)" "unprognostic (4.69e-3)" "unprognostic (4.39e-2)" ACBD4 FLJ13322 ENSG00000181513 "Acyl-CoA binding domain containing 4" Q8NC06 17 45132600-45144181 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 90.7" "Cell type enhanced" "Detected in many" "Enterocytes: 62.3;Proximal tubule cells: 39.6" "Cell type enhanced" "Detected in many" "Enterocytes: 62.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1199 "Hepatocytes: 147426.8;Proximal tubules: 92405.9" "Tissue enriched" "Detected in single" 3285 "liver: 328458.2" HPA051772 Approved Approved Nucleoplasm,Vesicles Yes No "Cluster 24: Non-specific - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 1: Enterocytes - Absorption and Digestion" 7 "Nucleoplasm, Vesicles" "HPA051772: " "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (5.37e-1)" "unprognostic (1.76e-1)" "unprognostic (3.66e-2)" "unprognostic (3.88e-2)" "unprognostic (1.21e-3)" "unprognostic (2.85e-1)" "unprognostic (5.05e-2)" "unprognostic (6.60e-2)" "potential prognostic favorable (2.59e-6)" "unprognostic (3.35e-3)" "potential prognostic favorable (3.97e-4)" "unprognostic (2.00e-3)" "unprognostic (2.67e-3)" "unprognostic (6.95e-2)" "unprognostic (7.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.45e-1)" "unprognostic (2.11e-2)" "unprognostic (7.58e-3)" "unprognostic (5.10e-3)" "unprognostic (3.26e-2)" "unprognostic (3.29e-1)" "unprognostic (2.97e-2)" "unprognostic (3.61e-1)" "unprognostic (4.21e-1)" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (1.97e-1)" "unprognostic (3.42e-2)" ACCSL ENSG00000205126 "1-aminocyclopropane-1-carboxylate synthase homolog (inactive) like" Q4AC99 11 44047981-44059977 "Predicted intracellular proteins" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Melanocytes: 10.3;Platelets: 5.7" "Group enriched" "Detected in some" 5 "Pigment cells: 10.3;Platelets: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 109470 "heart muscle: 10946986.6" HPA065042 Approved Cytosol NA NA "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" Cytosol "HPA065042: " ACLY "ACL, ATPCL, CLATP" ENSG00000131473 "ATP citrate lyase" P53396 17 41866917-41930542 "Cancer-related genes, Citric acid cycle related proteins, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism" Transferase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islet cells: 201.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Prostate - Prostate glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB007783, HPA022434, HPA022953, HPA022959, HPA028758" Enhanced Supported "Nucleoplasm,Primary cilium transition zone,Basal body,Cytosol,Principal piece" No No 4000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 39 Cytosol "Nucleoplasm, Primary cilium transition zone, Basal body, Principal piece" "CAB007783: , HPA022434: , HPA022953: , HPA022959: , HPA028758: " "unprognostic (1.22e-1)" "unprognostic (3.18e-2)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (1.55e-1)" "unprognostic (1.06e-1)" "unprognostic (2.26e-1)" "unprognostic (2.47e-1)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (4.59e-5)" "potential prognostic favorable (1.58e-6)" "unprognostic (1.50e-3)" "unprognostic (1.02e-1)" "unprognostic (1.90e-3)" "unprognostic (6.07e-3)" "unprognostic (5.74e-3)" "unprognostic (2.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.26e-1)" "unprognostic (4.50e-3)" "unprognostic (1.30e-1)" "unprognostic (3.87e-2)" "unprognostic (1.96e-1)" "unprognostic (2.16e-2)" "unprognostic (4.99e-2)" "unprognostic (1.31e-2)" "unprognostic (8.45e-2)" "unprognostic (1.16e-1)" "unprognostic (4.67e-1)" "unprognostic (1.89e-2)" "unprognostic (1.45e-1)" ACMSD ENSG00000153086 "Aminocarboxymuconate semialdehyde decarboxylase" Q8TDX5 2 134838616-134902034 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "kidney: 131.6;liver: 151.9" "Group enriched" "Detected in many" 4 "Hepatocytes: 315.2;Proximal tubule cells: 388.4" "Group enriched" "Detected in many" 4 "Hepatocytes: 315.2;Renal nephron cells: 388.4" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 23 "Kidney Renal Clear Cell Carcinoma (TCGA): 69.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 73.1;Liver Hepatocellular Carcinoma (TCGA): 60.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.6" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Glomeruli: 2655024.5;Hepatocytes: 1910431.2;Proximal tubules: 3665576.3" "Group enriched" "Detected in some" "kidney: 3327252.7;liver: 5934990.6" "HPA010533, HPA011179" Enhanced Approved Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 Cytosol "HPA010533: , HPA011179: " "unprognostic (1.44e-1)" "unprognostic (3.14e-1)" "unprognostic (2.06e-2)" "validated prognostic favorable (1.35e-8)" "validated prognostic favorable (3.64e-4)" "unprognostic (5.46e-3)" "unprognostic (8.71e-3)" "unprognostic (3.86e-2)" "unprognostic (5.77e-2)" "unprognostic (1.89e-1)" "unprognostic (1.76e-2)" "unprognostic (3.04e-1)" "unprognostic (8.85e-2)" ACOD1 "CAD, IRG1" ENSG00000102794 "Aconitate decarboxylase 1" A6NK06 13 76948511-76958638 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.3" "Cell type enriched" "Detected in some" 18 "monocytes: 54.9" "Cell type enriched" "Detected in some" 23 "Mononuclear phagocytes: 54.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 390 "T-cells: 38952.7" "Tissue enhanced" "Detected in many" "skin: 177416.7" "HPA040143, HPA058816" Uncertain Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 66: Lymphoid tissue - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Mitochondria Nucleoplasm "HPA040143: , HPA058816: " ACOT7 "ACH1, ACT, BACH, CTE-II, hBACH, LACH1, MGC1126" ENSG00000097021 "Acyl-CoA thioesterase 7" O00154 1 6264269-6393767 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 140.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 144.9;Enterocytes: 172.1;Goblet cells: 159.1;Late spermatids: 213.7;Mast cells: 161.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 213.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "NK-cell: 40.3;plasmacytoid DC: 35.8" "Group enriched" "Detected in many" 5 "dendritic cells: 35.8;NK-cells: 40.3" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Lactotropes, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 111713523.9;Microglia and Neuropil: 103913642.3;Neurons: 89231144.1" "Tissue enriched" "Detected in all" "cerebral cortex: 231681867.8" "HPA025735, HPA025762" Enhanced Supported Cytosol No No 62000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 70: Intestinal goblet cells - Mucin production" 13 Cytosol "HPA025735: , HPA025762: " "unprognostic (7.15e-2)" "unprognostic (3.96e-2)" "unprognostic (1.71e-2)" "unprognostic (4.31e-2)" "unprognostic (2.07e-2)" "unprognostic (1.27e-1)" "unprognostic (5.05e-3)" "unprognostic (7.41e-2)" "unprognostic (6.46e-2)" "unprognostic (3.29e-3)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.08e-2)" "validated prognostic unfavorable (8.35e-5)" "validated prognostic unfavorable (3.56e-6)" "potential prognostic unfavorable (1.17e-5)" "unprognostic (5.52e-2)" "unprognostic (4.90e-2)" "unprognostic (4.28e-2)" "unprognostic (1.40e-1)" "unprognostic (1.63e-1)" "unprognostic (5.89e-2)" "unprognostic (5.07e-2)" "unprognostic (1.31e-2)" "unprognostic (1.23e-1)" "unprognostic (3.49e-2)" "unprognostic (5.67e-2)" "unprognostic (1.28e-2)" "unprognostic (2.27e-1)" "unprognostic (7.50e-2)" "unprognostic (8.48e-2)" ACOX3 ENSG00000087008 "Acyl-CoA oxidase 3, pristanoyl" O15254 4 8366282-8440723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 101.4;Esophageal apical cells: 154.4;Syncytiotrophoblasts: 151.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 154.4;Trophoblast cells: 151.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "Stomach: 82960929.5" "HPA035840, HPA035841" Uncertain Approved Peroxisomes NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 Peroxisomes "HPA035840: , HPA035841: " "unprognostic (1.83e-1)" "unprognostic (2.56e-2)" "unprognostic (2.74e-1)" "unprognostic (2.40e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (3.21e-3)" "unprognostic (5.19e-2)" "unprognostic (2.78e-3)" "potential prognostic favorable (8.40e-4)" "unprognostic (5.07e-2)" "unprognostic (3.85e-3)" "unprognostic (2.33e-1)" "potential prognostic favorable (2.51e-4)" "unprognostic (1.78e-1)" "unprognostic (6.81e-2)" "unprognostic (8.52e-2)" "unprognostic (2.04e-2)" "unprognostic (9.11e-3)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (1.84e-2)" "unprognostic (1.90e-1)" "unprognostic (7.99e-2)" "unprognostic (6.22e-2)" "unprognostic (1.26e-1)" "unprognostic (2.76e-2)" "unprognostic (5.45e-2)" "unprognostic (2.45e-1)" "unprognostic (1.38e-1)" "unprognostic (1.95e-1)" "unprognostic (8.09e-2)" "unprognostic (2.34e-1)" ACRV1 "D11S4365, SP-10, SPACA2" ENSG00000134940 "Acrosomal vesicle protein 1" P26436 11 125671522-125680874 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 110.6" "Group enriched" "Detected in some" 66 "Early spermatids: 1056.1;Late primary spermatocytes: 445.8;Late spermatids: 332.2" "Cell type enriched" "Detected in some" 115 "Spermatogenic cell types: 1056.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038718, HPA038719" Enhanced Supported Acrosome "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Acrosome "HPA038718: , HPA038719: " "unprognostic (2.67e-1)" "unprognostic (5.02e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (4.10e-1)" ACSBG2 "BGR, DKFZp434K1635, PRTD-NY3" ENSG00000130377 "Acyl-CoA synthetase bubblegum family member 2" Q5FVE4 19 6135247-6193094 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 274 "testis: 120.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3180.8" "Cell type enriched" "Detected in many" 47 "Spermatogenic cell types: 3180.8" "Cell type enriched" "Detected in many" 4 "Bergmann glia: 41.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043421, HPA051013" Enhanced Supported Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Cytosol "HPA043421: , HPA051013: " ACSL5 "ACS2, ACS5, FACL5" ENSG00000197142 "Acyl-CoA synthetase long chain family member 5" Q9ULC5 10 112374116-112428379 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 211.6;intestine: 405.8;liver: 159.5" "Cell type enhanced" "Detected in many" "Colonocytes: 206.7;Endometrial ciliated cells: 185.0;Endometrial glandular cells: 606.6;Endometrial luminal cells: 265.4;Enterocytes: 943.9;Epididymal principal cells: 280.1;Urothelial cells: 449.6" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 449.6;Enterocytes: 943.9;Glandular cells: 606.6" "Cell type enhanced" "Detected in all" "endothelial cell: 116.0;leukocyte: 49.9" "Cancer enhanced" "Detected in all" "Rectum Adenocarcinoma (TCGA): 159.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 97.2;colorectal cancer: 99.3" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 36439037.1;Hepatocytes: 77940581.3" "Group enriched" "Detected in many" "intestine: 167857492.6;liver: 156414197.2" "HPA007162, CAB035986, CAB062546" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 51: Secretory epithelial cells - Mixed function" 9 Mitochondria Nucleoplasm "CAB035986: , CAB062546: , HPA007162: " "unprognostic (3.12e-3)" "unprognostic (1.46e-2)" "unprognostic (6.23e-2)" "unprognostic (8.94e-2)" "unprognostic (3.45e-1)" "unprognostic (8.33e-3)" "unprognostic (1.32e-1)" "unprognostic (6.12e-2)" "unprognostic (2.07e-2)" "unprognostic (8.68e-2)" "unprognostic (4.45e-3)" "unprognostic (1.91e-2)" "unprognostic (2.64e-1)" "unprognostic (8.36e-2)" "unprognostic (1.78e-1)" "unprognostic (3.83e-2)" "unprognostic (2.96e-1)" "unprognostic (1.73e-2)" "unprognostic (3.11e-2)" "unprognostic (4.15e-2)" "unprognostic (6.14e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.65e-2)" "unprognostic (7.27e-2)" "unprognostic (1.09e-2)" "unprognostic (2.33e-1)" "unprognostic (9.64e-2)" "unprognostic (1.37e-1)" "unprognostic (6.90e-2)" "unprognostic (1.37e-2)" "unprognostic (4.99e-2)" ACSS2 "ACAS2, AceCS, ACS, ACSA, dJ1161H23.1" ENSG00000131069 "Acyl-CoA synthetase short chain family member 2" Q9NR19 20 34872146-34927962 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Transcription, Transcription regulation" "Activator, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 109.9" "Cell type enhanced" "Detected in many" "Adipocytes: 425.7;Breast lactating cells: 357.2;Cardiomyocytes: 521.6;Colonocytes: 244.1;Goblet cells: 263.3;Myonuclei: 359.2" "Cell type enhanced" "Detected in all" "Adipocytes: 425.7;Myocytes: 521.6;Secretory cells: 357.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 34.5" "Group enriched" "Detected in many" 5 "dendritic cells: 22.6;granulocytes: 34.5;monocytes: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 39813888.6" "Tissue enhanced" "Detected in all" "liver: 30169987.8" "HPA004141, HPA004183, HPA070826" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 58000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 89: Adipocytes - Lipid metabolism" Nucleoplasm "Vesicles, Plasma membrane, Cytosol" "HPA004141: , HPA004183: , HPA070826: " "unprognostic (1.74e-3)" "unprognostic (1.77e-1)" "unprognostic (2.90e-3)" "unprognostic (9.24e-3)" "unprognostic (2.80e-2)" "unprognostic (2.44e-1)" "unprognostic (3.43e-2)" "unprognostic (3.02e-2)" "unprognostic (1.08e-1)" "unprognostic (2.49e-2)" "potential prognostic favorable (3.14e-6)" "unprognostic (7.73e-3)" "unprognostic (9.49e-3)" "unprognostic (9.16e-2)" "unprognostic (2.18e-2)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (8.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.22e-1)" "unprognostic (3.49e-1)" "unprognostic (1.84e-1)" "unprognostic (1.07e-1)" "unprognostic (3.62e-2)" "unprognostic (2.61e-2)" "unprognostic (5.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-1)" "unprognostic (3.16e-1)" "unprognostic (7.47e-3)" "unprognostic (2.05e-1)" ACSS3 FLJ21963 ENSG00000111058 "Acyl-CoA synthetase short chain family member 3" Q9H6R3 12 80936414-81261210 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.4" "Cell type enhanced" "Detected in many" "Adipocytes: 467.9;Adrenal cortex cells: 204.9;Astrocytes: 266.2;Bergmann glia: 212.0;Cardiomyocytes: 303.7;Ependymal cells: 244.9;Myonuclei: 270.3;Pituitary stem cells: 239.1" "Cell type enhanced" "Detected in many" "Adipocytes: 467.9" "Group enriched" "Detected in many" 6 "astrocyte: 268.8;Bergmann glia: 226.0;choroid plexus epithelial cell: 143.4;ependymal cell: 259.9;fibroblast: 278.4;pericyte: 312.5;vascular associated smooth muscle cell: 99.4" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 51.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 7.1;neutrophil: 2.2" "Lineage enriched" "Detected in single" 71 "granulocytes: 7.1" "Cancer enhanced" "Detected in many" "liver cancer: 10.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 49394391.1;Distal tubules: 100662681.2;Glomeruli: 27915098.6;Hepatocytes: 109545408.1;Proximal tubules: 110132870.8" "Tissue enhanced" "Detected in many" "liver: 37863887.0" "HPA039353, HPA047956, HPA061517" Approved Supported Mitochondria NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 2 Mitochondria "HPA039353: , HPA047956: , HPA061517: " "unprognostic (1.09e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (6.83e-3)" "unprognostic (2.81e-2)" "potential prognostic unfavorable (4.61e-6)" "unprognostic (3.00e-3)" "validated prognostic favorable (3.37e-10)" "validated prognostic favorable (2.87e-6)" "unprognostic (1.70e-3)" "unprognostic (2.05e-1)" "unprognostic (2.23e-1)" "unprognostic (1.81e-3)" "unprognostic (1.15e-1)" "unprognostic (4.10e-3)" "unprognostic (2.50e-3)" "unprognostic (1.02e-2)" "unprognostic (1.80e-2)" "unprognostic (3.39e-2)" "unprognostic (7.22e-2)" "unprognostic (6.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.23e-1)" "unprognostic (1.55e-1)" "unprognostic (1.17e-3)" "unprognostic (1.65e-1)" "unprognostic (1.36e-1)" "unprognostic (3.48e-2)" ACTL6B "ACTL6, BAF53B, SMARCN2" ENSG00000077080 "Actin like 6B" O94805 7 100643097-100656448 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 51.2;pituitary gland: 14.6" "Group enriched" "Detected in some" 4 "Adrenal medulla cells: 31.9;Brain excitatory neurons: 39.0;Brain inhibitory neurons: 36.2;Cone photoreceptor cells: 18.6;Corticotrophs: 29.5;Gonadotrophs: 37.7;Lactotrophs: 23.9;Other brain neurons: 26.2;Pancreatic islet cells: 17.5;Retinal amacrine cells: 40.4;Retinal bipolar cells: 21.5;Retinal ganglion cells: 42.5;Retinal horizontal cells: 34.1;Somatotrophs: 22.6;Thyrotrophs: 15.4" "Group enriched" "Detected in some" 5 "Adrenal endocrine cells: 31.9;Neuronal cells: 42.5;Pancreatic islet cells: 17.5;Pituitary endocrine cells: 37.7" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 9.4;Pancreatic Adenocarcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 7.5;Neuroblastoma: 27.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 9415047.8" "Tissue enriched" "Detected in single" 32681 "cerebral cortex: 3268108.5" HPA045126 Uncertain Approved "Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 28 "Nucleoli rim" "Mitotic chromosome" "HPA045126: " "unprognostic (5.10e-2)" "unprognostic (3.08e-3)" "unprognostic (3.21e-3)" ACTL7A ENSG00000187003 "Actin like 7A" Q9Y615 9 108862266-108863756 "Predicted intracellular proteins" "Differentiation, Fertilization, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1180 "testis: 218.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 7542.9" "Cell type enriched" "Detected in some" 994 "Spermatogenic cell types: 7542.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 63 "Oocytes: 6305.0" "Tissue enriched" "Detected in single" 1007 "skeletal muscle: 100742.9" HPA021624 Enhanced Supported "Perinuclear theca" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "Perinuclear theca" "HPA021624: " ACTL8 CT57 ENSG00000117148 "Actin like 8" Q9H568 1 17755333-17827063 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 6.8" "Cell type enriched" "Detected in some" 5 "Oocytes: 497.3" "Cell type enriched" "Detected in some" 5 "Oocytes: 497.3" "Cell type enhanced" "Detected in some" "fibroblast: 1.1;mammillary body: 1.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 27.0" "Testis - Spermatogonia" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 13589 "Oocytes: 1358912.5" "Not detected" "Not detected" HPA027176 Approved Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 39: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" 2 Cytosol "HPA027176: " "unprognostic (2.50e-3)" "unprognostic (2.52e-3)" "unprognostic (4.05e-2)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (1.00e-4)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (2.14e-2)" "unprognostic (4.74e-2)" "unprognostic (1.69e-1)" "unprognostic (1.97e-1)" "unprognostic (9.25e-2)" "unprognostic (1.86e-1)" "unprognostic (7.86e-2)" "unprognostic (9.43e-3)" ACTR10 "ACTR11, Arp10, Arp11, HARP11" ENSG00000131966 "Actin related protein 10" Q9NZ32 14 58200080-58235636 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 8 "Bile duct cancer: 55.7" "Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 5369743.2" HPA000699 Approved "Vesicles,Plasma membrane,Focal adhesion sites,Perinuclear theca,Connecting piece,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 38 "Vesicles, Plasma membrane" "Focal adhesion sites, Perinuclear theca, Connecting piece, Flagellar centriole, Mid piece, Principal piece" "HPA000699: " "unprognostic (1.94e-1)" "unprognostic (4.14e-1)" "unprognostic (4.39e-3)" "unprognostic (8.62e-3)" "unprognostic (1.58e-2)" "unprognostic (6.15e-2)" "unprognostic (1.51e-1)" "unprognostic (1.43e-1)" "unprognostic (6.34e-2)" "unprognostic (7.15e-2)" "unprognostic (1.06e-2)" "unprognostic (1.12e-1)" "unprognostic (2.23e-2)" "unprognostic (1.60e-3)" "unprognostic (8.08e-2)" "unprognostic (2.94e-2)" "unprognostic (8.92e-2)" "unprognostic (3.90e-3)" "unprognostic (3.12e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (9.28e-4)" "potential prognostic favorable (1.87e-4)" "unprognostic (4.44e-2)" "unprognostic (1.25e-1)" "unprognostic (9.21e-3)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (1.22e-1)" "unprognostic (1.19e-1)" "unprognostic (2.51e-1)" "unprognostic (1.09e-1)" ACTR1A "ARP1, Arp1A" ENSG00000138107 "Actin related protein 1A" P61163 10 102461881-102502712 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 183.2;Syncytiotrophoblasts: 157.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB037193, HPA047443" Approved Uncertain "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes NA 650000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 93 Microtubules "Cytokinetic bridge, Primary cilium, Cytosol" "CAB037193: , HPA047443: " "unprognostic (1.48e-1)" "unprognostic (3.32e-3)" "unprognostic (4.39e-1)" "unprognostic (1.07e-1)" "unprognostic (4.87e-2)" "unprognostic (8.24e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (4.11e-8)" "unprognostic (5.85e-2)" "unprognostic (2.31e-1)" "unprognostic (4.27e-3)" "unprognostic (1.57e-1)" "potential prognostic favorable (4.79e-4)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (1.80e-1)" "unprognostic (2.12e-2)" "unprognostic (2.32e-1)" "unprognostic (5.11e-2)" "unprognostic (1.64e-2)" "unprognostic (5.00e-2)" "unprognostic (4.40e-3)" "unprognostic (6.08e-2)" "unprognostic (1.93e-1)" "unprognostic (1.82e-1)" "unprognostic (1.73e-1)" "unprognostic (1.97e-1)" "unprognostic (4.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.68e-1)" "unprognostic (4.78e-2)" "unprognostic (1.36e-1)" ACTR1B "Arp1B, CTRN2" ENSG00000115073 "Actin related protein 1B" P42025 2 97655939-97664044 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA047443 Uncertain "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes NA 240000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 50 Microtubules "Cytokinetic bridge, Primary cilium, Cytosol" "HPA047443: " "unprognostic (8.58e-3)" "unprognostic (3.83e-3)" "unprognostic (1.60e-1)" "unprognostic (1.56e-1)" "unprognostic (8.45e-2)" "unprognostic (8.09e-2)" "unprognostic (3.05e-3)" "unprognostic (1.76e-2)" "unprognostic (1.69e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (2.93e-5)" "unprognostic (4.09e-2)" "unprognostic (1.09e-2)" "unprognostic (4.83e-3)" "unprognostic (1.61e-3)" "unprognostic (1.98e-2)" "unprognostic (9.76e-2)" "unprognostic (2.24e-1)" "unprognostic (7.64e-2)" "unprognostic (4.38e-1)" "unprognostic (2.13e-1)" "unprognostic (1.94e-1)" "unprognostic (1.79e-2)" "unprognostic (3.01e-1)" "unprognostic (9.24e-2)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (1.99e-1)" "unprognostic (3.68e-2)" "unprognostic (7.94e-2)" "unprognostic (3.78e-1)" ACTR6 "ARP6, FLJ13433" ENSG00000075089 "Actin related protein 6" Q9GZN1 12 100199122-100241865 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 136.5;Late primary spermatocytes: 180.3;Syncytiotrophoblasts: 134.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 180.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Capillaries: 3572556.4" "Tissue enriched" "Detected in some" "lymphoid tissue: 247466.5" "HPA038587, HPA038588" Uncertain Approved "Plasma membrane,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 24 "Plasma membrane, Cytosol" "HPA038587: , HPA038588: " "unprognostic (2.99e-1)" "unprognostic (3.69e-3)" "unprognostic (5.45e-2)" "unprognostic (1.01e-1)" "unprognostic (9.26e-2)" "unprognostic (2.48e-1)" "unprognostic (2.60e-1)" "unprognostic (2.62e-1)" "unprognostic (3.63e-3)" "potential prognostic unfavorable (1.33e-4)" "validated prognostic favorable (2.53e-6)" "validated prognostic favorable (9.92e-4)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (4.51e-10)" "unprognostic (1.06e-3)" "unprognostic (2.05e-2)" "unprognostic (2.52e-1)" "unprognostic (9.46e-2)" "unprognostic (2.49e-1)" "unprognostic (4.90e-2)" "unprognostic (2.95e-3)" "unprognostic (2.24e-2)" "unprognostic (2.32e-2)" "unprognostic (5.57e-1)" "unprognostic (4.76e-2)" "unprognostic (3.54e-1)" "unprognostic (2.91e-1)" "unprognostic (1.14e-1)" "unprognostic (2.01e-1)" "unprognostic (9.22e-2)" "unprognostic (7.65e-2)" ACTRT3 ARPM1 ENSG00000184378 "Actin related protein T3" Q9BYD9 3 169766921-169769561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "testis: 54.1" "Group enriched" "Detected in many" 5 "Early spermatids: 1180.4;Late primary spermatocytes: 533.9" "Cell type enriched" "Detected in many" 74 "Spermatogenic cell types: 1180.4" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 6406 "fallopian tube: 640606.6" "HPA035817, HPA035818" Approved Approved Nucleoplasm,Centrosome,Cytosol,Acrosome NA NA "Cluster 67: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 2 Nucleoplasm "Centrosome, Cytosol, Acrosome" "HPA035817: , HPA035818: " "unprognostic (1.47e-2)" "unprognostic (1.57e-1)" "unprognostic (4.99e-2)" "unprognostic (3.48e-1)" "unprognostic (1.01e-1)" "unprognostic (2.50e-1)" "unprognostic (1.31e-1)" "unprognostic (5.70e-3)" "unprognostic (6.91e-3)" "unprognostic (9.70e-2)" "unprognostic (3.80e-1)" "unprognostic (3.64e-3)" "unprognostic (1.26e-1)" "unprognostic (4.67e-2)" "unprognostic (9.98e-3)" "unprognostic (6.61e-2)" "unprognostic (1.16e-2)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (4.53e-3)" "unprognostic (5.73e-2)" "unprognostic (1.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (9.16e-4)" "unprognostic (1.33e-2)" ACVR1B "ActRIB, ACVRLK4, ALK4, SKR2" ENSG00000135503 "Activin A receptor type 1B" P36896 12 51951699-51997078 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 186.3;Neutrophils: 160.8;Renal connecting tubule cells: 182.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 425371.0;Microglia and Neuropil: 496978.0" "Not detected" "Not detected" "CAB026126, HPA063761" Approved Approved "Vesicles,Primary cilium,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 16 Cytosol "Vesicles, Primary cilium" "CAB026126: , HPA063761: " "unprognostic (4.44e-1)" "unprognostic (3.54e-2)" "unprognostic (1.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.77e-2)" "unprognostic (2.03e-2)" "unprognostic (3.42e-1)" "unprognostic (6.70e-3)" "unprognostic (1.82e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-2)" "unprognostic (4.91e-3)" "unprognostic (1.30e-1)" "unprognostic (1.17e-3)" "unprognostic (4.44e-2)" "unprognostic (4.47e-2)" "unprognostic (1.63e-1)" "unprognostic (1.02e-1)" "unprognostic (2.60e-2)" "unprognostic (2.65e-1)" "unprognostic (5.59e-1)" "unprognostic (1.37e-1)" "unprognostic (1.47e-3)" "unprognostic (9.58e-2)" "unprognostic (9.62e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (1.08e-2)" "unprognostic (7.34e-2)" "unprognostic (2.51e-1)" ACYP1 ENSG00000119640 "Acylphosphatase 1" P07311 14 75053237-75069483 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 140.5;Epididymal efferent duct ciliated cells: 138.1;Fallopian tube ciliated cells: 147.3;Late primary spermatocytes: 134.9;Respiratory ciliated cells: 126.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Cell type enhanced" "Detected in all" "Fallopian tube cells: 10019184.3" "Low tissue specificity" "Detected in all" HPA034944 Approved Approved Nucleoplasm,Cytosol NA NA 100000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" Cytosol Nucleoplasm "HPA034944: " "unprognostic (2.07e-1)" "unprognostic (1.78e-3)" "unprognostic (1.84e-1)" "potential prognostic favorable (3.86e-4)" "unprognostic (8.30e-3)" "unprognostic (2.51e-1)" "unprognostic (2.98e-1)" "unprognostic (1.09e-2)" "unprognostic (2.92e-1)" "unprognostic (1.28e-3)" "unprognostic (2.19e-1)" "unprognostic (2.24e-2)" "unprognostic (9.35e-2)" "potential prognostic unfavorable (1.32e-7)" "unprognostic (2.78e-2)" "unprognostic (6.25e-2)" "unprognostic (2.32e-1)" "unprognostic (3.54e-2)" "unprognostic (9.22e-2)" "unprognostic (8.37e-2)" "unprognostic (1.72e-1)" "unprognostic (7.78e-3)" "unprognostic (9.51e-3)" "unprognostic (5.26e-2)" "unprognostic (5.56e-2)" "unprognostic (1.65e-1)" "unprognostic (2.47e-1)" "unprognostic (1.98e-2)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (3.51e-1)" ADA ADA1 ENSG00000196839 "Adenosine deaminase" P00813 20 44584896-44652252 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 454.0;lymphoid tissue: 228.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 439.1;Extravillous trophoblasts: 213.3;Fibro-adipogenic progenitors: 109.6;monocytes: 87.1;Oocytes: 110.5;Parietal cells: 212.1;pDCs: 88.2" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 212.1;Myocytes: 439.1;Trophoblast cells: 213.3" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 9.8;leukocyte: 24.5;oligodendrocyte: 12.4;pericyte: 12.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 163.0;NK-cell: 90.4;non-classical monocyte: 351.2;plasmacytoid DC: 211.2" "Group enriched" "Detected in all" 4 "dendritic cells: 211.2;monocytes: 351.2;NK-cells: 90.4" "Cancer enhanced" "Detected in all" "Leukemia: 168.9" "Kidney - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 8983059.6" "Tissue enriched" "Detected in all" "intestine: 410509839.0" "HPA001399, CAB004307, HPA023884, CAB080432" Enhanced Supported "Plasma membrane,Cytosol" No No 210000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 77: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "Plasma membrane" Cytosol "CAB004307: , CAB080432: , HPA001399: , HPA023884: " "unprognostic (2.37e-2)" "unprognostic (1.78e-1)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (1.42e-1)" "unprognostic (1.95e-2)" "unprognostic (7.39e-2)" "unprognostic (1.70e-2)" "unprognostic (1.50e-2)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (1.73e-5)" "unprognostic (3.05e-2)" "potential prognostic unfavorable (5.82e-5)" "potential prognostic unfavorable (1.35e-6)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (6.28e-6)" "unprognostic (1.13e-2)" "unprognostic (2.01e-2)" "unprognostic (1.29e-1)" "unprognostic (1.90e-1)" "unprognostic (6.99e-2)" "unprognostic (3.57e-3)" "unprognostic (1.22e-3)" "unprognostic (7.92e-2)" "unprognostic (2.84e-1)" "unprognostic (4.38e-2)" "unprognostic (3.72e-2)" "unprognostic (1.30e-1)" "unprognostic (1.90e-1)" "unprognostic (2.48e-2)" "unprognostic (1.41e-3)" ADAL ENSG00000168803 "Adenosine deaminase like" Q6DHV7 15 43330672-43354569 "Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 153.2;Undifferentiated spermatogonia: 79.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 153.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 855276.9" "Tissue enhanced" "Detected in many" "fallopian tube: 1288720.4" "HPA039879, HPA048175, HPA058795" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Nucleoplasm "Nuclear speckles, Vesicles" "HPA039879: , HPA048175: , HPA058795: " "unprognostic (2.74e-2)" "unprognostic (1.72e-1)" "unprognostic (8.60e-2)" "unprognostic (3.65e-2)" "unprognostic (9.59e-2)" "unprognostic (1.96e-2)" "unprognostic (4.93e-2)" "unprognostic (7.09e-2)" "unprognostic (9.32e-2)" "unprognostic (1.70e-2)" "potential prognostic favorable (1.22e-5)" "unprognostic (4.39e-2)" "unprognostic (3.15e-3)" "unprognostic (1.23e-1)" "unprognostic (8.28e-2)" "unprognostic (7.86e-2)" "unprognostic (1.35e-1)" "unprognostic (4.62e-2)" "unprognostic (3.72e-3)" "unprognostic (1.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.16e-1)" "unprognostic (3.74e-3)" "unprognostic (3.99e-2)" "unprognostic (2.24e-2)" "unprognostic (4.57e-1)" "unprognostic (5.65e-2)" "unprognostic (3.96e-2)" "unprognostic (1.18e-1)" "unprognostic (5.10e-2)" "unprognostic (2.52e-1)" ADAM17 "CD156B, cSVP, TACE" ENSG00000151694 "ADAM metallopeptidase domain 17" P78536 2 9488486-9556732 "CD markers, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "monocytes: 418.7;Neutrophils: 898.2" "Cell type enhanced" "Detected in all" "Neutrophils: 898.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 3605391.2" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2373389.0" "HPA010738, HPA051575" Approved Approved Cytosol NA NA 470000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 23 Cytosol "HPA010738: , HPA051575: " "unprognostic (4.40e-3)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "unprognostic (3.29e-2)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (7.15e-2)" "unprognostic (5.00e-2)" "unprognostic (8.72e-3)" "unprognostic (2.47e-1)" "potential prognostic favorable (2.98e-5)" "unprognostic (5.49e-2)" "unprognostic (4.94e-2)" "potential prognostic unfavorable (6.27e-4)" "unprognostic (2.49e-2)" "unprognostic (4.73e-2)" "unprognostic (2.51e-2)" "unprognostic (1.95e-1)" "unprognostic (1.76e-1)" "unprognostic (1.88e-1)" "unprognostic (2.79e-2)" "unprognostic (4.49e-3)" "potential prognostic unfavorable (5.32e-7)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (2.51e-1)" "unprognostic (9.03e-2)" "unprognostic (3.03e-1)" "unprognostic (1.25e-1)" "unprognostic (2.31e-2)" "unprognostic (1.75e-2)" ADAM23 MDC3 ENSG00000114948 "ADAM metallopeptidase domain 23" O75077 2 206443532-206621127 "Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.5;parathyroid gland: 77.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 344.4;Brain inhibitory neurons: 435.1;Cardiomyocytes: 167.4;Oligodendrocyte progenitor cells: 173.2;Other brain neurons: 245.7;Retinal amacrine cells: 171.4;Retinal bipolar cells: 294.6;Retinal ganglion cells: 502.2;Schwann cells: 198.2;Thymic myoid cells: 172.7;Thyrotrophs: 126.8" "Cell type enhanced" "Detected in many" "Glial cells: 198.2;Myocytes: 167.4;Neuronal cells: 502.2;Stromal cells: 172.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 58.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "memory CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 16 "T-cells: 2.1" "Cancer enhanced" "Detected in many" "Myeloma: 47.8" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Fibroblasts_2, Pituitary gland - Thyrotropes, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 18784884.5;Microglia and Neuropil: 19390310.1;Neurons: 5842467.4" "Tissue enriched" "Detected in single" 352881 "cerebral cortex: 35288102.4" "HPA012130, CAB033276" Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in brain" "Cell adhesion" NA NA 25000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Nucleoplasm, Plasma membrane" "CAB033276: , HPA012130: " "unprognostic (5.31e-2)" "unprognostic (7.03e-2)" "unprognostic (1.88e-1)" "unprognostic (1.69e-1)" "unprognostic (5.20e-2)" "unprognostic (2.96e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-2)" "unprognostic (1.37e-2)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (1.46e-5)" "unprognostic (6.02e-2)" "unprognostic (1.52e-1)" "unprognostic (4.70e-2)" "unprognostic (1.12e-1)" "unprognostic (1.19e-2)" "unprognostic (1.49e-2)" "unprognostic (5.37e-2)" "unprognostic (1.88e-1)" "unprognostic (3.01e-1)" "unprognostic (1.13e-2)" "unprognostic (7.77e-2)" "unprognostic (8.27e-3)" "unprognostic (3.72e-2)" "unprognostic (1.35e-1)" ADAMTS13 "C9orf8, DKFZp434C2322, FLJ42993, MGC118899, MGC118900, TTP, vWF-CP, VWFCP" ENSG00000160323 "ADAM metallopeptidase with thrombospondin type 1 motif 13" Q76LX8 9 133414358-133459402 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 62.5" "Cell type enhanced" "Detected in some" "Astrocytes: 19.6;Bergmann glia: 12.0;Brain excitatory neurons: 12.2;Brain inhibitory neurons: 13.5;Distal convoluted tubule cells: 9.3;Early spermatids: 7.4;Ependymal cells: 14.2;Hepatic stellate cells: 6.5;Loop of henle epithelial cells: 9.0;Oligodendrocyte progenitor cells: 5.8;Oligodendrocytes: 8.4;Other brain neurons: 9.4;Papillary tip epithelial cells: 6.7;Podocytes: 6.5;Proximal tubule cells: 10.7;Renal collecting duct intercalated cells: 6.8;Renal collecting duct principal cells: 10.1;Renal connecting tubule cells: 10.4" "Cell type enhanced" "Detected in some" "Ciliated cells: 14.2;Ductal cells: 10.4;Glial cells: 19.6;Neuronal cells: 13.5;Renal nephron cells: 10.7;Spermatogenic cell types: 7.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 53 "Collecting ducts: 5340.5" "Not detected" "Not detected" "HPA042014, HPA042844, HPA052077" Approved Uncertain Vesicles "Secreted to blood" "Blood coagulation" NA NA 1300000000 160000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 1 Vesicles "HPA042014: , HPA042844: , HPA052077: " "unprognostic (1.60e-1)" "unprognostic (5.66e-2)" "unprognostic (9.63e-2)" "unprognostic (2.89e-1)" "unprognostic (2.36e-1)" "unprognostic (1.81e-1)" "potential prognostic favorable (7.15e-4)" "unprognostic (2.38e-2)" "unprognostic (1.20e-1)" "unprognostic (5.01e-2)" "unprognostic (2.03e-1)" "unprognostic (5.43e-2)" "unprognostic (1.37e-1)" "unprognostic (3.55e-1)" "unprognostic (6.25e-3)" "unprognostic (1.81e-1)" "unprognostic (6.16e-2)" "potential prognostic favorable (2.39e-4)" "unprognostic (2.75e-2)" "unprognostic (1.19e-1)" "unprognostic (5.03e-2)" "unprognostic (1.44e-1)" "unprognostic (1.73e-1)" "unprognostic (1.75e-1)" "unprognostic (3.04e-2)" "unprognostic (8.37e-2)" ADAMTS18 ADAMTS21 ENSG00000140873 "ADAM metallopeptidase with thrombospondin type 1 motif 18" Q8TE60 16 77247813-77435034 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 13.8;placenta: 19.4" "Cell type enhanced" "Detected in many" "Bergmann glia: 58.7;Brain excitatory neurons: 84.7;Medullary thymic epithelial cells: 86.4;Müller glia: 163.6;Oligodendrocytes: 107.4;Pituicytes/FSCs: 47.7;Pituitary stem cells: 134.3;Renal collecting duct intercalated cells: 62.7;Retinal amacrine cells: 72.4;Rod photoreceptor cells: 56.5;Salivary acinar cells: 65.2;Thyrotrophs: 96.6;Tuft cells: 126.8" "Cell type enhanced" "Detected in many" "Glial cells: 163.6;Neuronal cells: 84.7;Pituitary endocrine cells: 96.6;Secretory gland support: 126.8;Stem cells: 134.3" "Cell type enhanced" "Detected in many" "oligodendrocyte: 164.1;upper rhombic lip: 304.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "liver cancer: 2.6;testis cancer: 9.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells" "Region enriched" "Detected in single" 5 "cerebellum: 3.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA044326 Uncertain Approved "Midbody,Mitotic spindle" "Secreted to extracellular matrix" Enzyme Yes NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Midbody, Mitotic spindle" "HPA044326: " "unprognostic (1.43e-1)" "unprognostic (2.24e-1)" "unprognostic (4.82e-2)" "unprognostic (6.05e-2)" "unprognostic (1.03e-1)" ADAMTS19 ENSG00000145808 "ADAM metallopeptidase with thrombospondin type 1 motif 19" 5 129460281-129738683 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 9.5;endometrium 1: 9.2;smooth muscle: 5.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 393.6;Brain excitatory neurons: 103.7;Brain inhibitory neurons: 221.9;Cytotrophoblasts: 256.0;Endometrial stromal cells: 139.4;Myonuclei: 171.4;Podocytes: 1207.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 393.6;Neuronal cells: 221.9;Renal nephron cells: 1207.1;Trophoblast cells: 256.0" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 404.3" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.6;Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 7.7" "Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Prostate - Fibroblasts" "Region enriched" "Detected in single" 5 "olfactory bulb: 2.6" "Low region specificity" "Detected in all" "HPA056171, HPA058438" Uncertain Approved Vesicles,Midbody "Secreted to extracellular matrix" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" "Vesicles, Midbody" "HPA056171: , HPA058438: " "unprognostic (3.26e-1)" "unprognostic (1.05e-3)" "unprognostic (7.99e-2)" "unprognostic (7.63e-2)" ADAMTS20 GON-1 ENSG00000173157 "ADAM metallopeptidase with thrombospondin type 1 motif 20" P59510 12 43353866-43552203 "Cancer-related genes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 50.3;Retinal bipolar cells: 84.7;Thymic myoid cells: 27.2" "Group enriched" "Detected in some" 4 "Neuronal cells: 84.7;Stromal cells: 27.2;Trophoblast cells: 50.3" "Group enriched" "Detected in many" 6 "committed oligodendrocyte precursor: 52.2;lower rhombic lip: 192.9" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "medulla oblongata: 3.6;pons: 6.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 9.4" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027608, HPA027609" Uncertain Approved "Golgi apparatus,Microtubules,Mitotic spindle,Primary cilium,Basal body,Cytosol" "Secreted to extracellular matrix" Enzyme Yes NA "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Golgi apparatus, Primary cilium" "Microtubules, Mitotic spindle, Basal body, Cytosol" "HPA027608: , HPA027609: " "potential prognostic favorable (1.94e-4)" "unprognostic (8.43e-2)" ADAMTS9 KIAA1312 ENSG00000163638 "ADAM metallopeptidase with thrombospondin type 1 motif 9" Q9P2N4 3 64515654-64688000 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "ER-Golgi transport, Protein transport, Transport" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 39.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 373.3;Endometrial stromal cells: 775.2;Epicardial cells: 891.5;Lymphatic endothelial cells: 525.3;Mesothelial cells: 619.0;Pericytes: 751.9;Podocytes: 1242.5;Vascular endothelial cells: 1365.5;Vascular smooth muscle cells: 774.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 891.5;Endothelial cells: 1365.5;Mural cells: 774.0;Renal nephron cells: 1242.5;Stromal cells: 775.2" "Cell type enhanced" "Detected in many" "astrocyte: 283.4;vascular associated smooth muscle cell: 140.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 45.5;testis cancer: 37.3" "Breast - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 54 "Glomeruli: 5407.8" "Not detected" "Not detected" "HPA028567, HPA028577, HPA028601" Approved Supported "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" Transport No NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Endoplasmic reticulum" Vesicles "HPA028567: , HPA028577: , HPA028601: " "unprognostic (5.51e-2)" "unprognostic (3.97e-1)" "unprognostic (5.10e-2)" "unprognostic (8.00e-2)" "unprognostic (1.39e-1)" "unprognostic (1.19e-2)" "unprognostic (4.10e-1)" "unprognostic (1.53e-1)" "unprognostic (3.48e-2)" "unprognostic (1.16e-1)" "unprognostic (2.31e-3)" "unprognostic (1.56e-3)" "unprognostic (4.07e-2)" "unprognostic (3.87e-3)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (2.28e-2)" "unprognostic (1.34e-2)" "unprognostic (6.40e-2)" "unprognostic (1.99e-1)" "unprognostic (6.47e-2)" "unprognostic (9.33e-2)" "unprognostic (1.41e-2)" "unprognostic (5.01e-1)" "unprognostic (1.21e-1)" "unprognostic (2.21e-1)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (9.64e-2)" "unprognostic (7.02e-3)" "unprognostic (1.05e-1)" ADAR "ADAR1, DRADA, G1P1, IFI4" ENSG00000160710 "Adenosine deaminase RNA specific" P55265 1 154581695-154628013 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, mRNA processing, RNA-mediated gene silencing" "DNA-binding, Hydrolase, RNA-binding" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 335.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 127138246.1" "Low tissue specificity" "Detected in all" "HPA003890, HPA051519, CAB056157" Enhanced Enhanced Nucleoplasm,Nucleoli No No 2400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 68 Nucleoli Nucleoplasm "CAB056157: , HPA003890: , HPA051519: " "unprognostic (3.47e-2)" "unprognostic (4.39e-2)" "unprognostic (2.98e-3)" "unprognostic (6.46e-3)" "unprognostic (7.32e-2)" "unprognostic (2.19e-1)" "unprognostic (1.52e-1)" "unprognostic (8.87e-2)" "unprognostic (8.67e-2)" "unprognostic (3.36e-2)" "potential prognostic favorable (5.50e-7)" "unprognostic (4.62e-2)" "unprognostic (3.11e-2)" "unprognostic (7.54e-2)" "unprognostic (1.09e-1)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (1.30e-1)" "unprognostic (1.28e-1)" "unprognostic (2.02e-1)" "unprognostic (8.28e-2)" "unprognostic (1.04e-2)" "unprognostic (2.52e-1)" "unprognostic (7.20e-2)" "unprognostic (1.55e-1)" "unprognostic (1.99e-1)" "unprognostic (4.23e-1)" "unprognostic (2.36e-1)" "unprognostic (2.74e-1)" "unprognostic (3.76e-2)" "unprognostic (2.19e-1)" ADAT3 TAD3 ENSG00000213638 "Adenosine deaminase tRNA specific 3" 19 1905399-1913447 "Human disease related genes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 13.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA058899 Uncertain Approved Nucleoplasm No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm "HPA058899: " "unprognostic (2.70e-1)" "unprognostic (2.48e-1)" "unprognostic (4.55e-2)" "unprognostic (1.94e-1)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (2.39e-1)" "potential prognostic favorable (7.44e-4)" "unprognostic (9.04e-2)" "unprognostic (1.30e-1)" "unprognostic (5.63e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (1.43e-5)" "unprognostic (2.87e-2)" "unprognostic (1.95e-1)" "unprognostic (5.39e-2)" "unprognostic (2.43e-1)" "unprognostic (3.69e-3)" "unprognostic (3.56e-2)" "unprognostic (1.10e-1)" "unprognostic (4.60e-2)" "unprognostic (1.06e-2)" "unprognostic (1.21e-2)" "unprognostic (2.56e-1)" "potential prognostic favorable (2.20e-4)" "unprognostic (1.41e-1)" "unprognostic (2.44e-2)" "unprognostic (4.76e-2)" ADCY3 AC3 ENSG00000138031 "Adenylate cyclase 3" O60266 2 24819169-24920237 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis, Olfaction, Sensory transduction" "Calmodulin-binding, Lyase" Obesity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 277.4;Decidual stromal cells: 122.6;Endometrial stromal cells: 107.0;Leydig cells: 110.9;Pericytes: 335.0;Retinal ganglion cells: 158.4;Somatotrophs: 144.7;Vascular smooth muscle cells: 248.2" "Cell type enhanced" "Detected in many" "Mural cells: 335.0;Secretory cells: 277.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Skin - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 114082.2;Fallopian tube cells: 108978.6;Microglia and Neuropil: 199516.7" "Tissue enriched" "Detected in single" 584 "cerebral cortex: 58395.1" "CAB010223, HPA068616" Approved Uncertain "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 75: Ovary - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 110: Mural cells - ECM organization" 14 "Nucleoplasm, Primary cilium" "Nucleoli, Golgi apparatus, Plasma membrane, Primary cilium transition zone, Basal body" "CAB010223: , HPA068616: " "unprognostic (8.72e-3)" "unprognostic (1.13e-1)" "unprognostic (1.99e-1)" "unprognostic (4.97e-2)" "unprognostic (1.49e-1)" "unprognostic (2.50e-2)" "unprognostic (7.79e-3)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (3.37e-2)" "unprognostic (3.38e-2)" "unprognostic (4.86e-2)" "unprognostic (1.91e-3)" "unprognostic (1.50e-1)" "unprognostic (2.53e-1)" "unprognostic (7.56e-2)" "unprognostic (2.49e-2)" "unprognostic (2.64e-3)" "unprognostic (3.36e-2)" "unprognostic (1.78e-1)" "unprognostic (6.48e-3)" "unprognostic (1.42e-2)" "unprognostic (4.03e-1)" "unprognostic (2.09e-1)" "unprognostic (3.85e-2)" "potential prognostic favorable (6.24e-4)" "unprognostic (4.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (3.45e-2)" "unprognostic (1.13e-2)" ADCY5 AC5 ENSG00000173175 "Adenylate cyclase 5" O95622 3 123282296-123449090 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.2;heart muscle: 99.3" "Cell type enhanced" "Detected in many" "Adipocytes: 247.0;Brain inhibitory neurons: 248.8;Cardiomyocytes: 313.3;Gonadotrophs: 174.6;Lactotrophs: 137.2;Loop of henle epithelial cells: 140.6;Oligodendrocytes: 127.2;Peritubular myoid cells: 288.5;Somatotrophs: 135.3;Thyrotrophs: 222.5;Vascular smooth muscle cells: 180.3" "Cell type enhanced" "Detected in many" "Adipocytes: 247.0;Myocytes: 313.3;Neuronal cells: 248.8;Pituitary endocrine cells: 222.5;Stromal cells: 288.5" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 336.9;medium spiny neuron: 668.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 8.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Region enriched" "Detected in all" 5 "basal ganglia: 388.1" "Region enriched" "Detected in all" 6 "basal ganglia: 206.2" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 4923998.7;Capillaries: 7261970.2;Cardiomyocytes: 7911271.5" "Tissue enhanced" "Detected in many" "blood vessel: 7143101.4" "HPA017730, HPA077682" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Vesicles, Plasma membrane" "Nucleoplasm, Nuclear bodies, Primary cilium" "HPA017730: , HPA077682: " "unprognostic (1.08e-2)" "unprognostic (6.13e-2)" "unprognostic (1.66e-2)" "potential prognostic favorable (3.19e-4)" "unprognostic (5.94e-2)" "unprognostic (2.67e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.09e-2)" "unprognostic (2.83e-1)" "potential prognostic favorable (4.14e-10)" "unprognostic (3.47e-3)" "unprognostic (1.76e-2)" "unprognostic (3.00e-1)" "unprognostic (9.27e-3)" "unprognostic (1.01e-2)" "unprognostic (5.22e-2)" "unprognostic (3.31e-2)" "unprognostic (1.26e-2)" "unprognostic (1.35e-1)" "unprognostic (4.58e-1)" "unprognostic (2.31e-2)" "unprognostic (1.54e-1)" "unprognostic (3.99e-2)" "unprognostic (5.62e-2)" "unprognostic (1.15e-1)" "unprognostic (1.28e-2)" "unprognostic (8.51e-2)" "unprognostic (2.33e-1)" ADCY9 AC9 ENSG00000162104 "Adenylate cyclase 9" O60503 16 3953387-4116442 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "cAMP biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 48.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 294.6;Choroid plexus epithelial cells: 791.3;Myonuclei: 588.6;Oocytes: 350.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 791.3;Myocytes: 588.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1510151.6;Proximal tubules: 1695512.6" "Tissue enriched" "Detected in some" "cerebral cortex: 3224123.8" "HPA041328, HPA044225" Approved Approved "Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 7 "Plasma membrane, Cytosol" "Primary cilium, Basal body" "HPA041328: , HPA044225: " "unprognostic (4.22e-2)" "unprognostic (1.72e-1)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (3.18e-1)" "unprognostic (1.68e-3)" "unprognostic (7.40e-2)" "unprognostic (2.14e-2)" "unprognostic (2.28e-2)" "unprognostic (2.35e-2)" "potential prognostic favorable (3.63e-11)" "unprognostic (1.36e-2)" "unprognostic (1.01e-2)" "unprognostic (3.92e-1)" "unprognostic (2.47e-1)" "unprognostic (2.43e-3)" "unprognostic (7.95e-3)" "unprognostic (9.43e-2)" "unprognostic (1.28e-1)" "unprognostic (6.35e-3)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (1.78e-1)" "unprognostic (4.51e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.61e-1)" "unprognostic (9.43e-2)" "unprognostic (2.74e-1)" "unprognostic (3.81e-1)" "unprognostic (5.00e-3)" ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843844-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 498.9;Rod photoreceptor cells: 990.1" "Cell type enhanced" "Detected in all" "Neuronal cells: 990.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 169571265.4;Microglia and Neuropil: 152189166.2" "Tissue enriched" "Detected in all" "cerebral cortex: 272875759.5" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 720000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 79: Photoreceptor cells - Phototransduction" 17 "Plasma membrane" Nucleoplasm "CAB009794: , HPA035873: , HPA035874: " "unprognostic (7.79e-3)" "unprognostic (6.30e-2)" "unprognostic (7.88e-2)" "unprognostic (2.84e-3)" "unprognostic (1.40e-1)" "unprognostic (2.27e-1)" "unprognostic (7.26e-2)" "unprognostic (1.14e-3)" "unprognostic (7.65e-2)" "unprognostic (6.98e-2)" "validated prognostic favorable (4.82e-8)" "validated prognostic favorable (4.23e-6)" "unprognostic (6.24e-3)" "unprognostic (3.21e-3)" "unprognostic (8.48e-3)" "unprognostic (1.96e-1)" "unprognostic (9.69e-3)" "unprognostic (4.36e-3)" "unprognostic (3.47e-2)" "unprognostic (1.30e-1)" "unprognostic (6.23e-2)" "unprognostic (1.48e-1)" "unprognostic (8.19e-2)" "unprognostic (1.19e-1)" "unprognostic (7.96e-2)" "unprognostic (8.29e-2)" "unprognostic (2.63e-1)" "unprognostic (4.41e-2)" "unprognostic (1.49e-1)" "unprognostic (1.58e-1)" "unprognostic (9.48e-2)" ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 304 "liver: 2559.5" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 243.2" "Cell type enriched" "Detected in some" 17 "Hepatocytes: 243.2" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 229 "Liver Hepatocellular Carcinoma (TCGA): 407.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Adipocytes (Breast), Liver - Hepatocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland)" "Group enriched" "Detected in some" "Collecting ducts: 121842106.4;Hepatocytes: 93035541.5" "Tissue enhanced" "Detected in many" "liver: 164432749.7" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA 32000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 93: Hepatocytes - Bile production & excretion" "Plasma membrane, Cytosol" "Nucleoplasm, Primary cilium, Primary cilium transition zone, Basal body" "CAB009562: , HPA047814: , HPA060902: " "potential prognostic favorable (1.95e-4)" "unprognostic (2.75e-3)" "unprognostic (1.50e-3)" "unprognostic (3.22e-2)" ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1408.8;liver: 5476.4" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 5446.8" "Cell type enriched" "Detected in many" 5 "Hepatocytes: 5446.8" "Group enriched" "Detected in some" 39 "fibroblast: 44.1;pericyte: 47.6;vascular associated smooth muscle cell: 15.1" "Cancer enriched" "Detected in many" 27 "Liver Hepatocellular Carcinoma (TCGA): 832.6" "Region enhanced" "Detected in many" "choroid plexus: 24.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Spleen - Fibroblasts_2, Testis - Endothelial cells" "Cell type enriched" "Detected in many" "Hepatocytes: 3851244173.0" "Tissue enriched" "Detected in all" "liver: 4942934337.1" "HPA047814, HPA060902" Supported Approved "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA 41000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 "Plasma membrane, Cytosol" "Nucleoplasm, Primary cilium, Primary cilium transition zone, Basal body" "HPA047814: , HPA060902: " "unprognostic (1.36e-2)" "unprognostic (5.62e-2)" "potential prognostic favorable (9.38e-5)" "unprognostic (4.06e-2)" "unprognostic (1.40e-1)" "unprognostic (1.17e-1)" "unprognostic (9.45e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (1.19e-4)" "validated prognostic favorable (6.15e-4)" "validated prognostic favorable (6.43e-4)" "potential prognostic favorable (2.37e-4)" "unprognostic (2.02e-2)" "unprognostic (8.00e-3)" "unprognostic (8.33e-2)" "unprognostic (9.62e-3)" "unprognostic (9.31e-2)" "unprognostic (2.70e-2)" "unprognostic (3.20e-1)" "unprognostic (2.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.86e-1)" "unprognostic (7.62e-2)" "unprognostic (1.95e-3)" "unprognostic (4.10e-1)" "unprognostic (1.36e-1)" "unprognostic (3.91e-3)" ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 562.7;liver: 1927.2;stomach 1: 538.9" "Cell type enhanced" "Detected in some" "Colonocytes: 55.7;Conjunctival goblet cells: 340.8;Enteric stem cells: 116.6;Enteric transient amplifying cells: 182.6;Foveolar cells: 86.5;Gastric chief cells: 52.4;Hepatocytes: 196.9;Mucous neck cells: 98.3;Paneth cells: 116.0;Respiratory basal cells: 60.8;Respiratory deuterosomal cells: 58.1;Respiratory secretory cells: 131.6" "Cell type enhanced" "Detected in many" "Goblet cells: 340.8;Hepatocytes: 196.9;Proliferating cells: 182.6;Secretory cells: 131.6;Secretory gland support: 116.0;Stem cells: 116.6" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 461.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 53.7" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells" "Cell type enriched" "Detected in many" "Hepatocytes: 361253136.7" "Tissue enriched" "Detected in many" "liver: 535322293.2" "HPA047814, HPA060902" Supported Approved "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA 19000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 11 "Plasma membrane, Cytosol" "Nucleoplasm, Primary cilium, Primary cilium transition zone, Basal body" "HPA047814: , HPA060902: " "unprognostic (6.19e-2)" "unprognostic (1.26e-1)" "unprognostic (4.94e-2)" "unprognostic (6.65e-2)" "unprognostic (4.46e-3)" "unprognostic (1.12e-1)" "unprognostic (5.87e-2)" "unprognostic (8.09e-2)" "unprognostic (1.68e-1)" "unprognostic (1.40e-3)" "validated prognostic favorable (3.38e-4)" "validated prognostic favorable (5.73e-9)" "unprognostic (1.07e-2)" "unprognostic (1.08e-2)" "unprognostic (1.17e-2)" "unprognostic (8.99e-2)" "unprognostic (1.74e-1)" "unprognostic (2.19e-2)" "unprognostic (2.61e-1)" "unprognostic (1.59e-1)" "unprognostic (1.82e-1)" "unprognostic (9.15e-2)" "unprognostic (1.95e-1)" "unprognostic (2.53e-1)" ADH4 ADH-2 ENSG00000198099 "Alcohol dehydrogenase 4 (class II), pi polypeptide" P08319 4 99123657-99157792 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "liver: 4815.9" "Cell type enriched" "Detected in many" 21 "Hepatocytes: 1345.1" "Cell type enriched" "Detected in many" 21 "Hepatocytes: 1345.1" "Cell type enhanced" "Detected in some" "ependymal cell: 5.8" "Cancer enriched" "Detected in some" 30 "Liver Hepatocellular Carcinoma (TCGA): 353.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.8" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Hepatocytes: 1735566372.6" "Tissue enriched" "Detected in many" "liver: 1659068834.2" HPA020525 Enhanced Uncertain Nucleoplasm,Cytosol NA NA 14000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" "Nucleoplasm, Cytosol" "HPA020525: " "unprognostic (4.38e-2)" "unprognostic (3.25e-1)" "potential prognostic unfavorable (4.88e-5)" "potential prognostic favorable (1.89e-6)" "unprognostic (1.20e-3)" "unprognostic (6.14e-2)" "unprognostic (6.74e-2)" "unprognostic (3.64e-2)" "unprognostic (3.93e-3)" ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151202-74709963 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.2" "Cell type enhanced" "Detected in all" "Sertoli cells: 1311.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 37118448.4" "Tissue enriched" "Detected in all" "liver: 127497312.9" "CAB032876, HPA038391, HPA038409, HPA075222" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 510000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 87: B-cells - Adaptive immunity: Humoral response" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032876: , HPA038391: , HPA038409: , HPA075222: " "unprognostic (2.53e-1)" "validated prognostic unfavorable (8.76e-5)" "validated prognostic unfavorable (4.44e-5)" "unprognostic (2.54e-1)" "unprognostic (1.58e-1)" "unprognostic (3.95e-2)" "unprognostic (6.25e-3)" "potential prognostic favorable (5.63e-5)" "potential prognostic unfavorable (9.09e-5)" "unprognostic (1.21e-1)" "potential prognostic favorable (5.93e-6)" "unprognostic (6.80e-2)" "unprognostic (1.46e-1)" "unprognostic (1.11e-3)" "unprognostic (2.50e-2)" "unprognostic (8.38e-2)" "unprognostic (6.47e-2)" "unprognostic (1.02e-1)" "unprognostic (5.95e-2)" "unprognostic (3.33e-1)" "unprognostic (9.44e-2)" "unprognostic (3.62e-3)" "unprognostic (4.00e-3)" "unprognostic (5.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.80e-1)" "unprognostic (1.48e-1)" "unprognostic (3.79e-1)" "unprognostic (5.19e-2)" "unprognostic (2.58e-2)" "unprognostic (8.55e-2)" ADNP "ADNP1, KIAA0784" ENSG00000101126 "Activity dependent neuroprotector homeobox" Q9H2P0 20 50888916-50931437 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Autism spectrum disorder, Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 35637755.6" "Low tissue specificity" "Detected in many" "HPA006371, HPA050560" Supported Approved "Nucleoplasm,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 42 "Nucleoplasm, Centrosome" "Primary cilium, Primary cilium tip, Basal body" "HPA006371: , HPA050560: " "unprognostic (4.39e-2)" "unprognostic (1.02e-2)" "unprognostic (3.69e-1)" "unprognostic (1.46e-1)" "unprognostic (6.66e-2)" "unprognostic (8.20e-2)" "unprognostic (2.09e-1)" "unprognostic (6.61e-2)" "unprognostic (5.74e-2)" "unprognostic (1.33e-2)" "unprognostic (4.06e-3)" "unprognostic (3.19e-2)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (6.69e-5)" "unprognostic (1.38e-2)" "unprognostic (4.36e-1)" "unprognostic (2.92e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-2)" "unprognostic (2.06e-2)" "unprognostic (1.92e-2)" "unprognostic (7.35e-2)" "unprognostic (1.73e-2)" "unprognostic (2.88e-2)" "unprognostic (7.76e-3)" "unprognostic (1.32e-2)" "unprognostic (7.29e-2)" "unprognostic (2.67e-1)" "unprognostic (3.46e-1)" "unprognostic (1.23e-2)" "unprognostic (3.45e-1)" ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.6;testis: 20.2" "Cell type enhanced" "Detected in many" "Adipocytes: 20.5;Astrocytes: 30.3;Brain excitatory neurons: 21.9;Breast secretory cells: 19.9;Müller glia: 60.9;Oligodendrocyte progenitor cells: 54.5;Oligodendrocytes: 55.1;Pancreatic duct cells: 30.8;Podocytes: 138.9;Retinal amacrine cells: 19.7;Sertoli cells: 28.8" "Cell type enhanced" "Detected in many" "Ductal cells: 30.8;Glial cells: 60.9;Renal nephron cells: 138.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 66.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 51.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Podocytes, Prostate - Fibroblasts, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044383, CAB080543" Approved Supported "Plasma membrane,Primary cilium" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 57: Podocytes - Glomerular filtration" 9 "Plasma membrane" "Primary cilium" "CAB080543: , HPA044383: " "unprognostic (1.90e-2)" "unprognostic (7.77e-3)" "unprognostic (6.77e-2)" "unprognostic (6.62e-2)" "unprognostic (1.57e-1)" "unprognostic (6.55e-2)" "unprognostic (5.86e-2)" "unprognostic (1.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.03e-1)" "unprognostic (5.16e-3)" "unprognostic (8.88e-2)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (3.10e-2)" "unprognostic (2.84e-1)" "unprognostic (5.65e-3)" "unprognostic (1.94e-3)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (8.47e-2)" "unprognostic (1.06e-3)" "unprognostic (5.04e-2)" "unprognostic (3.75e-2)" "unprognostic (9.22e-2)" "unprognostic (1.41e-1)" "unprognostic (1.31e-1)" "unprognostic (1.20e-1)" "unprognostic (3.51e-2)" "unprognostic (9.36e-2)" "unprognostic (2.44e-2)" "unprognostic (2.23e-2)" ADRB2 "ADRB2R, ADRBR, B2AR, BAR" ENSG00000169252 "Adrenoceptor beta 2" P07550 5 148826611-148828623 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 32.4;skin 1: 36.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 175.2;Basal keratinocytes: 326.3;Breast lactating cells: 230.8;Conjunctival goblet cells: 70.9;Mast cells: 138.8;Ocular epithelial cells: 152.7;Suprabasal keratinocytes: 184.6" "Cell type enhanced" "Detected in many" "Alveolar cells: 175.2;Barrier epithelial cells: 152.7;Basal cells: 326.3;Secretory cells: 230.8;Suprabasal cells: 184.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 63.3;leukocyte: 27.5" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 22.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "head and neck cancer: 50.9" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA075322 Supported "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 88 "Plasma membrane" "Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "HPA075322: " "unprognostic (4.34e-2)" "unprognostic (4.20e-2)" "unprognostic (1.49e-1)" "unprognostic (5.93e-2)" "unprognostic (1.66e-2)" "unprognostic (2.46e-1)" "unprognostic (1.31e-2)" "unprognostic (2.35e-1)" "unprognostic (5.14e-3)" "potential prognostic favorable (6.64e-7)" "unprognostic (3.59e-2)" "unprognostic (1.34e-3)" "unprognostic (1.11e-2)" "potential prognostic favorable (8.63e-4)" "unprognostic (4.60e-3)" "unprognostic (1.35e-1)" "unprognostic (4.01e-2)" "unprognostic (1.19e-1)" "unprognostic (2.08e-2)" "unprognostic (7.70e-3)" "unprognostic (2.20e-1)" "unprognostic (2.45e-2)" "unprognostic (1.48e-1)" "unprognostic (3.00e-2)" "unprognostic (5.62e-2)" "unprognostic (1.16e-1)" ADSL ENSG00000239900 "Adenylosuccinate lyase" P30566 22 40346461-40390463 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" Lyase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 323.5;tongue: 226.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 25.0;Enteric stem cells: 30.9;Enteric transient amplifying cells: 33.7;Oocytes: 41.4;Paneth cells: 30.9" "Cell type enhanced" "Detected in many" "Oocytes: 41.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Oocytes: 224728943.9;Skeletal myofibers: 174964705.0" "Low tissue specificity" "Detected in all" "HPA000525, CAB019285" Enhanced Enhanced Cytosol NA NA 320000 "Cluster 33: Non-specific - ATP binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 66: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein processing" 6 Cytosol "CAB019285: , HPA000525: " "unprognostic (7.10e-3)" "unprognostic (8.33e-2)" "unprognostic (2.40e-1)" "unprognostic (1.81e-1)" "unprognostic (2.47e-2)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (9.73e-2)" "unprognostic (3.10e-3)" "unprognostic (6.22e-3)" "potential prognostic favorable (3.05e-6)" "unprognostic (4.62e-3)" "unprognostic (1.41e-1)" "validated prognostic unfavorable (9.44e-7)" "validated prognostic unfavorable (9.84e-8)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (7.34e-2)" "unprognostic (1.23e-2)" "unprognostic (1.44e-1)" "unprognostic (2.55e-2)" "unprognostic (2.92e-2)" "unprognostic (1.18e-1)" "unprognostic (2.72e-1)" "unprognostic (1.68e-3)" "unprognostic (8.41e-2)" "unprognostic (4.91e-1)" "unprognostic (5.00e-2)" "unprognostic (3.74e-1)" "unprognostic (1.47e-1)" "unprognostic (2.17e-1)" ADSS2 ADSS ENSG00000035687 "Adenylosuccinate synthase 2" P30520 1 244408494-244451909 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 215.1;Neutrophil progenitors: 726.7" "Cell type enhanced" "Detected in all" "Neutrophils: 726.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 72206948.6" HPA024400 Supported Approved "Plasma membrane,Cytosol" NA NA 500000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Cytosol "Plasma membrane" "HPA024400: " "unprognostic (1.08e-1)" "unprognostic (2.33e-2)" "unprognostic (1.35e-1)" "unprognostic (1.11e-2)" "unprognostic (2.15e-1)" "unprognostic (1.19e-1)" "unprognostic (4.94e-2)" "unprognostic (1.22e-1)" "unprognostic (7.72e-2)" "potential prognostic favorable (6.04e-4)" "unprognostic (2.35e-1)" "unprognostic (2.24e-2)" "unprognostic (1.97e-2)" "unprognostic (5.96e-3)" "unprognostic (9.89e-3)" "unprognostic (1.35e-2)" "unprognostic (3.18e-1)" "unprognostic (1.45e-2)" "unprognostic (4.83e-2)" "unprognostic (4.41e-3)" "unprognostic (4.01e-2)" "unprognostic (1.05e-1)" "unprognostic (3.20e-2)" "unprognostic (1.29e-1)" "unprognostic (1.59e-1)" "unprognostic (1.99e-1)" "unprognostic (2.88e-1)" "unprognostic (1.78e-1)" "unprognostic (3.92e-1)" AFAP1L2 "Em:AC005383.4, FLJ14564, KIAA1914, XB130" ENSG00000169129 "Actin filament associated protein 1 like 2" Q8N4X5 10 114294824-114404756 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.8;parathyroid gland: 64.6;thyroid gland: 77.0" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 213.7;Podocytes: 126.7;Renal collecting duct principal cells: 135.6;Renal connecting tubule cells: 112.9;Schwann cells: 130.9;Tuft cells: 265.1" "Cell type enhanced" "Detected in many" "Ductal cells: 135.6;Glial cells: 213.7;Renal nephron cells: 126.7;Secretory gland support: 265.1" "Group enriched" "Detected in many" 6 "committed oligodendrocyte precursor: 171.8;endothelial cell: 254.2;oligodendrocyte precursor cell: 253.0;pericyte: 117.4;vascular associated smooth muscle cell: 104.9" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 82.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.6;T-cells: 1.8" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Skin - Outer root sheath cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 102.6" "Group enriched" "Detected in many" "Collecting ducts: 35812878.6;Glomeruli: 10405873.2" "Tissue enriched" "Detected in many" "lymphoid tissue: 7501440.9" HPA037843 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 33: Thyroid gland - Tissue development" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Cytosol "Plasma membrane" "HPA037843: " "unprognostic (1.63e-2)" "unprognostic (9.10e-3)" "unprognostic (3.96e-2)" "unprognostic (2.77e-2)" "unprognostic (8.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.18e-2)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" "unprognostic (4.30e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (3.81e-3)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (2.28e-1)" "unprognostic (1.54e-1)" "unprognostic (9.87e-2)" "unprognostic (3.04e-2)" "unprognostic (5.34e-3)" "unprognostic (1.19e-3)" "unprognostic (9.70e-3)" "unprognostic (2.03e-3)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (6.38e-2)" "unprognostic (2.32e-1)" "unprognostic (7.44e-2)" "unprognostic (5.60e-2)" "unprognostic (2.17e-1)" "unprognostic (4.84e-2)" "unprognostic (6.82e-2)" "unprognostic (1.73e-1)" "unprognostic (5.43e-2)" AFF1 "AF-4, AF4, FEL, MLLT2, PBM1" ENSG00000172493 "ALF transcription elongation factor 1" P51825 4 86935002-87141039 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 1283.5;Renal collecting duct principal cells: 1628.5;Syncytiotrophoblasts: 1153.9" "Cell type enhanced" "Detected in all" "Ductal cells: 1628.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 8042644.7" "Not detected" "Not detected" HPA069947 Approved Nucleoplasm,Mitochondria No No "Cluster 7: Non-specific - Innate immune response" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 18 "Nucleoplasm, Mitochondria" "HPA069947: " "unprognostic (1.63e-2)" "unprognostic (1.01e-1)" "unprognostic (1.60e-1)" "unprognostic (7.40e-3)" "unprognostic (6.36e-2)" "unprognostic (1.82e-1)" "unprognostic (8.73e-2)" "unprognostic (2.39e-1)" "unprognostic (2.31e-2)" "potential prognostic unfavorable (4.05e-4)" "validated prognostic favorable (4.81e-6)" "validated prognostic favorable (5.19e-4)" "unprognostic (6.38e-2)" "unprognostic (6.53e-2)" "unprognostic (6.29e-2)" "unprognostic (3.43e-1)" "unprognostic (2.33e-2)" "unprognostic (1.71e-2)" "unprognostic (3.74e-2)" "unprognostic (4.13e-2)" "unprognostic (4.91e-2)" "unprognostic (8.86e-2)" "unprognostic (3.09e-3)" "unprognostic (3.12e-2)" "unprognostic (1.32e-3)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" "unprognostic (5.27e-2)" AFF4 "AF5Q31, MCEF" ENSG00000072364 "ALF transcription elongation factor 4" Q9UHB7 5 132875395-132963634 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1359221.0" "Tissue enriched" "Detected in single" 1301 "lymphoid tissue: 130108.1" "HPA023690, HPA029634, HPA076229" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 39 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "HPA023690: , HPA029634: , HPA076229: " "unprognostic (9.93e-3)" "unprognostic (1.99e-2)" "unprognostic (7.60e-2)" "unprognostic (3.58e-2)" "unprognostic (3.41e-2)" "unprognostic (4.22e-2)" "unprognostic (2.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (7.35e-5)" "potential prognostic favorable (6.29e-9)" "unprognostic (2.23e-3)" "unprognostic (2.80e-1)" "unprognostic (1.22e-1)" "unprognostic (2.02e-3)" "unprognostic (2.40e-1)" "unprognostic (1.30e-1)" "unprognostic (8.96e-2)" "unprognostic (9.30e-2)" "unprognostic (2.94e-2)" "unprognostic (2.99e-3)" "unprognostic (1.95e-2)" "unprognostic (1.22e-3)" "unprognostic (1.40e-1)" "unprognostic (8.63e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "unprognostic (3.71e-2)" "unprognostic (1.53e-1)" "unprognostic (8.55e-3)" "unprognostic (1.22e-1)" AFG3L2 "SCA28, SPAX5" ENSG00000141385 "AFG3 like matrix AAA peptidase subunit 2" Q9Y4W6 18 12328944-12377227 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 96.6;tongue: 92.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 435197383.0" "Group enriched" "Detected in all" "cerebral cortex: 71046975.6;heart muscle: 244362904.6" "HPA004479, HPA004480" Enhanced Enhanced "Mitochondria,Perinuclear theca,Calyx,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 24 Mitochondria "Perinuclear theca, Calyx, Connecting piece, Mid piece, Principal piece" "HPA004479: , HPA004480: " "unprognostic (8.39e-2)" "unprognostic (1.75e-1)" "unprognostic (2.47e-1)" "unprognostic (1.11e-1)" "unprognostic (3.24e-2)" "unprognostic (4.43e-1)" "unprognostic (2.50e-1)" "unprognostic (1.89e-2)" "unprognostic (4.04e-3)" "unprognostic (6.81e-3)" "validated prognostic favorable (2.24e-11)" "validated prognostic favorable (5.25e-6)" "unprognostic (1.24e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (6.75e-6)" "unprognostic (5.12e-2)" "unprognostic (5.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.01e-2)" "unprognostic (1.57e-1)" "unprognostic (2.61e-1)" "unprognostic (2.81e-2)" "unprognostic (1.22e-1)" "unprognostic (7.18e-2)" "unprognostic (2.36e-2)" "unprognostic (2.12e-2)" "unprognostic (4.42e-2)" "unprognostic (2.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.03e-3)" "unprognostic (3.97e-2)" AFP "FETA, HPAFP" ENSG00000081051 "Alpha fetoprotein" P02771 4 73431138-73456174 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "liver: 3.4" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 141.2" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 141.2" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.1" "Group enriched" "Detected in some" 16 "Liver Hepatocellular Carcinoma (TCGA): 235.4;Testicular Germ Cell Tumor (TCGA): 87.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "liver cancer: 642.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11321 "Alveolar cell types: 1612618.8;Smooth muscle cells: 651508.2" "Not detected" "Not detected" "HPA010607, HPA023600, CAB024283, CAB025339, CAB080122" Approved Approved "Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 3010000 3000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 6 "Golgi apparatus" "CAB024283: , CAB025339: , CAB080122: , HPA010607: , HPA023600: " "unprognostic (4.04e-1)" "unprognostic (1.27e-1)" "unprognostic (2.13e-1)" "unprognostic (4.96e-2)" "unprognostic (6.73e-3)" "unprognostic (6.89e-2)" AGAP2 CENTG1 ENSG00000135439 "ArfGAP with GTPase domain, ankyrin repeat and PH domain 2" Q99490 12 57723761-57742157 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 181.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 41.0;Brain inhibitory neurons: 35.4;Hematopoietic stem cells: 24.3;Neutrophil progenitors: 39.9;Neutrophils: 56.5;NK-cells: 21.5;Other brain neurons: 14.4;Pericytes: 29.6;Retinal amacrine cells: 18.2;T-cells: 20.9" "Cell type enhanced" "Detected in many" "Mural cells: 29.6;Neuronal cells: 41.0;Neutrophils: 56.5;Stem cells: 24.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 74.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 19.8" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 21092222.7;Microglia and Neuropil: 27983085.7" "Group enriched" "Detected in some" "bone marrow: 15062385.6;cerebral cortex: 31053534.9;lymphoid tissue: 20617198.4" "HPA023474, HPA075831" Enhanced Supported "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Nucleoplasm, Cytosol" "Midbody ring" "HPA023474: , HPA075831: " "unprognostic (1.25e-1)" "unprognostic (1.35e-3)" "potential prognostic favorable (8.17e-5)" "unprognostic (2.64e-2)" "unprognostic (1.60e-2)" "unprognostic (3.58e-2)" "unprognostic (5.04e-1)" "unprognostic (1.45e-3)" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.84e-1)" "unprognostic (7.27e-2)" "unprognostic (2.00e-2)" "unprognostic (2.99e-3)" "unprognostic (5.24e-2)" "unprognostic (2.68e-1)" "unprognostic (7.85e-3)" "unprognostic (1.23e-1)" "unprognostic (3.10e-1)" "unprognostic (2.75e-1)" "unprognostic (4.24e-2)" "unprognostic (4.77e-2)" "unprognostic (2.40e-2)" "unprognostic (2.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.71e-2)" "unprognostic (2.26e-1)" AGBL2 "CCP2, FLJ23598" ENSG00000165923 "AGBL carboxypeptidase 2" Q5U5Z8 11 47659591-47715389 "Enzymes, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 5.1;testis: 11.4" "Cell type enriched" "Detected in some" 4 "Ependymal cells: 116.6" "Cell type enriched" "Detected in some" 6 "Ciliated cells: 116.6" "Cell type enriched" "Detected in many" 4 "ependymal cell: 120.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 164082 "Keratinocytes: 16408236.7" "Not detected" "Not detected" HPA007718 Uncertain Supported "Nucleoli,Basal body,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Nucleoli, Basal body, Cytosol, Flagellar centriole" "Mid piece, Principal piece, End piece" "HPA007718: " "unprognostic (3.83e-2)" "unprognostic (1.58e-2)" "unprognostic (2.70e-2)" "unprognostic (6.19e-3)" "unprognostic (6.26e-3)" "unprognostic (7.38e-2)" "unprognostic (1.22e-1)" AGBL5 "CCP5, FLJ21839" ENSG00000084693 "AGBL carboxypeptidase 5" Q8NDL9 2 27042364-27070622 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "parathyroid gland: 46.9;testis: 180.4" "Group enriched" "Detected in many" 5 "Early spermatids: 283.7;Late primary spermatocytes: 405.4;Late spermatids: 555.2" "Cell type enriched" "Detected in many" 9 "Spermatogenic cell types: 555.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 268 "Fallopian tube cells: 25658.3;Macrophages: 27893.5" "Not detected" "Not detected" HPA030981 Uncertain Approved "Microtubules,Cytokinetic bridge,Primary cilium,Centriolar satellite,Basal body" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Cytokinetic bridge, Primary cilium" "Microtubules, Centriolar satellite, Basal body" "HPA030981: " "unprognostic (1.24e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" "unprognostic (1.95e-2)" "unprognostic (2.67e-2)" "unprognostic (1.27e-1)" "unprognostic (2.62e-1)" "unprognostic (7.46e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (2.04e-3)" "unprognostic (1.85e-1)" "unprognostic (8.77e-3)" "validated prognostic unfavorable (1.13e-5)" "validated prognostic unfavorable (2.43e-6)" "unprognostic (2.24e-1)" "unprognostic (3.75e-1)" "unprognostic (4.54e-2)" "unprognostic (2.37e-1)" "unprognostic (2.72e-1)" "unprognostic (4.22e-1)" "unprognostic (2.39e-1)" "unprognostic (1.18e-1)" "unprognostic (2.46e-1)" "unprognostic (4.54e-3)" "unprognostic (5.69e-2)" "unprognostic (1.24e-1)" "unprognostic (2.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.94e-2)" "unprognostic (6.95e-2)" AGFG2 "HRBL, RABR" ENSG00000106351 "ArfGAP with FG repeats 2" O95081 7 100539203-100568220 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "salivary gland: 272.4" "Cell type enhanced" "Detected in many" "Epicardial cells: 106.9;Esophageal apical cells: 195.8;Lacrimal acinar cells: 130.4;Salivary acinar cells: 175.1" "Cell type enhanced" "Detected in all" "Acinar cells: 175.1;Apical squamous epithelial cells: 195.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 3600960.4" "Tissue enhanced" "Detected in many" "salivary gland: 2916858.0" "HPA019689, HPA020129, HPA073562" Enhanced Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 82: Salivary gland - Secretion" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" Cytosol "HPA019689: , HPA020129: , HPA073562: " "unprognostic (6.16e-2)" "unprognostic (9.97e-2)" "unprognostic (7.31e-2)" "unprognostic (2.26e-1)" "unprognostic (8.05e-2)" "unprognostic (3.84e-2)" "unprognostic (6.09e-2)" "unprognostic (5.82e-2)" "unprognostic (2.32e-2)" "unprognostic (3.48e-2)" "potential prognostic favorable (5.66e-8)" "unprognostic (4.75e-2)" "unprognostic (4.74e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-1)" "unprognostic (8.38e-2)" "unprognostic (2.63e-1)" "unprognostic (1.37e-1)" "unprognostic (5.70e-2)" "unprognostic (5.64e-2)" "unprognostic (6.10e-2)" "unprognostic (6.05e-3)" "unprognostic (1.72e-1)" "unprognostic (1.55e-1)" "unprognostic (1.56e-1)" "unprognostic (2.35e-1)" "unprognostic (9.51e-2)" "unprognostic (3.28e-1)" "unprognostic (1.27e-1)" "unprognostic (2.47e-1)" "unprognostic (1.71e-1)" AGR2 "AG2, HAG-2, PDIA17, XAG-2" ENSG00000106541 "Anterior gradient 2, protein disulphide isomerase family member" O95994 7 16791811-16833433 "Predicted intracellular proteins" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 600.4;intestine: 1148.3;stomach 1: 1323.9" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 5149.5;Endometrial secretory cells: 2331.3;Enteric stem cells: 1534.2;Enteric transient amplifying cells: 1667.4;Fallopian tube ciliated cells: 2564.8;Foveolar cells: 3724.5;Gastric chief cells: 2238.7;Gastric progenitor cells: 5670.1;Goblet cells: 6674.9;Mucous neck cells: 2518.9;Respiratory deuterosomal cells: 2354.2;Respiratory secretory cells: 3712.2;Submucosal glandular cells: 2000.8" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 3724.5;Goblet cells: 6674.9;Proliferating cells: 5670.1;Secretory cells: 3712.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 605.6;Gastric cancer: 837.5" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 87617888.2;Fallopian tube cells: 207683639.2" "Group enriched" "Detected in many" "intestine: 1691119184.2;salivary gland: 423984305.9" HPA007912 Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" 296 "Endoplasmic reticulum" "HPA007912: " "potential prognostic favorable (8.86e-4)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (3.68e-1)" "unprognostic (1.60e-1)" "unprognostic (9.65e-3)" "unprognostic (3.21e-3)" "potential prognostic unfavorable (4.17e-5)" "unprognostic (1.76e-2)" "unprognostic (5.19e-2)" "potential prognostic unfavorable (3.91e-5)" "unprognostic (4.70e-3)" "unprognostic (5.97e-3)" "unprognostic (4.14e-2)" "unprognostic (4.61e-1)" "unprognostic (4.01e-1)" "unprognostic (7.94e-3)" "unprognostic (6.57e-2)" "unprognostic (2.51e-1)" "unprognostic (3.88e-3)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (1.82e-2)" "unprognostic (5.40e-2)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (3.00e-1)" AGTPBP1 "CCP1, KIAA1035, Nna1" ENSG00000135049 "ATP/GTP binding carboxypeptidase 1" Q9UPW5 9 85546539-85742029 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 56.8;retina: 43.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 676.9;Endometrial ciliated cells: 494.8;Monocyte progenitors: 524.3;monocytes: 517.7;Neutrophil progenitors: 1490.7;Neutrophils: 3053.4;Oligodendrocytes: 545.2" "Cell type enriched" "Detected in all" 4 "Neutrophils: 3053.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 1180805.6;Microglia and Neuropil: 963147.4;Neurons: 1541321.6" "Tissue enhanced" "Detected in some" "cerebral cortex: 655084.5;lymphoid tissue: 636895.8" "HPA057208, HPA071094" Approved Supported "Nucleoplasm,Plasma membrane,Primary cilium,Centriolar satellite,Basal body" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 3 Nucleoplasm "Plasma membrane, Primary cilium, Centriolar satellite, Basal body" "HPA057208: , HPA071094: " "unprognostic (1.34e-2)" "unprognostic (3.22e-1)" "unprognostic (2.07e-2)" "unprognostic (3.72e-1)" "unprognostic (1.69e-1)" "unprognostic (9.35e-3)" "unprognostic (1.12e-1)" "unprognostic (1.73e-2)" "unprognostic (4.73e-2)" "unprognostic (1.98e-1)" "potential prognostic favorable (1.23e-4)" "unprognostic (1.00e-2)" "unprognostic (6.08e-2)" "unprognostic (1.87e-2)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (4.97e-2)" "unprognostic (1.08e-1)" "unprognostic (2.94e-3)" "unprognostic (2.77e-2)" "unprognostic (1.76e-2)" "unprognostic (4.83e-2)" "unprognostic (6.56e-2)" "unprognostic (4.10e-2)" "unprognostic (1.67e-3)" "unprognostic (1.75e-2)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.30e-1)" AHCTF1 ELYS ENSG00000153207 "AT-hook containing transcription factor 1" Q8WYP5 1 246839098-246931948 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, mRNA transport, Protein transport, Translocation, Transport" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 616.1" "Cell type enhanced" "Detected in all" "Neutrophils: 616.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 3.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "bone marrow: 3495817.0;intestine: 9710664.3" HPA031658 Uncertain Supported "Nucleoplasm,Nuclear membrane,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 24 "Nucleoplasm, Nuclear membrane, Nuclear bodies" "HPA031658: " "unprognostic (1.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.65e-1)" "unprognostic (9.39e-2)" "unprognostic (1.18e-1)" "unprognostic (3.68e-2)" "unprognostic (6.04e-2)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-2)" "potential prognostic favorable (3.96e-4)" "unprognostic (6.72e-2)" "unprognostic (4.44e-3)" "unprognostic (2.96e-2)" "unprognostic (7.09e-2)" "unprognostic (1.58e-2)" "unprognostic (8.57e-3)" "unprognostic (1.00e-1)" "unprognostic (2.78e-1)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (6.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.49e-1)" "unprognostic (7.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" "unprognostic (3.10e-1)" "unprognostic (2.71e-2)" "unprognostic (7.19e-3)" AHCYL2 "ADOHCYASE3, IRBIT2, KIAA0828, long-IRBIT" ENSG00000158467 "Adenosylhomocysteinase like 2" Q96HN2 7 129225030-129430211 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 258.9;intestine: 166.5" "Cell type enhanced" "Detected in many" "Astrocytes: 700.0;Choroid plexus epithelial cells: 2725.8;Pituicytes/FSCs: 1134.1;Pituitary stem cells: 834.2;Renal collecting duct intercalated cells: 822.2;Retinal pigment epithelial cells: 848.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 2725.8;Glial cells: 1134.1" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 2527.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 10 "choroid plexus: 1038.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 4313667.9" "Tissue enhanced" "Detected in many" "cerebral cortex: 8897844.5" HPA053128 Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA 91000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 12 Cytosol "Nucleoplasm, Vesicles" "HPA053128: " "unprognostic (1.26e-1)" "unprognostic (2.29e-1)" "unprognostic (3.31e-1)" "unprognostic (3.10e-1)" "unprognostic (3.46e-2)" "unprognostic (5.08e-3)" "unprognostic (1.53e-2)" "unprognostic (1.35e-1)" "potential prognostic favorable (9.63e-4)" "unprognostic (7.25e-2)" "validated prognostic favorable (3.57e-4)" "validated prognostic favorable (5.64e-4)" "unprognostic (1.89e-2)" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (1.09e-2)" "unprognostic (9.33e-2)" "unprognostic (2.79e-2)" "unprognostic (2.54e-1)" "unprognostic (1.08e-1)" "unprognostic (8.63e-2)" "unprognostic (2.55e-1)" "unprognostic (5.50e-3)" "unprognostic (1.16e-2)" "unprognostic (7.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.13e-1)" "potential prognostic favorable (8.67e-4)" "unprognostic (4.27e-1)" "unprognostic (5.53e-2)" "unprognostic (5.13e-3)" AHI1 "FLJ20069, JBTS3, ORF1" ENSG00000135541 "Abelson helper integration site 1" Q8N157 6 135283407-135498434 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation" "Developmental protein" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 25.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1511.2;Corticotrophs: 1111.8;Gonadotrophs: 1277.8;Lactotrophs: 2085.0;Rod photoreceptor cells: 2047.6;Somatotrophs: 1928.7;Thyrotrophs: 2329.2" "Cell type enhanced" "Detected in all" "Neuronal cells: 2047.6;Pituitary endocrine cells: 2329.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 9079 "Fallopian tube cells: 907939.0" "Tissue enriched" "Detected in single" 11915 "lymphoid tissue: 1191456.3" "HPA031698, HPA046684" Approved Supported "Primary cilium,Centrosome" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 10 Centrosome "Primary cilium" "HPA031698: , HPA046684: " "unprognostic (4.98e-2)" "unprognostic (2.00e-3)" "unprognostic (3.49e-1)" "unprognostic (6.10e-3)" "unprognostic (7.27e-2)" "unprognostic (6.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.53e-1)" "unprognostic (1.94e-2)" "unprognostic (8.92e-3)" "unprognostic (4.52e-3)" "unprognostic (2.58e-2)" "unprognostic (1.54e-1)" "unprognostic (8.50e-2)" "unprognostic (2.53e-2)" "unprognostic (2.10e-1)" "unprognostic (2.72e-2)" "unprognostic (3.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.21e-2)" "unprognostic (1.71e-1)" "unprognostic (3.18e-3)" "unprognostic (1.92e-1)" "unprognostic (1.71e-3)" "unprognostic (5.82e-3)" "unprognostic (8.71e-2)" "unprognostic (2.54e-2)" "unprognostic (1.57e-1)" "unprognostic (1.41e-1)" "unprognostic (7.77e-2)" AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 294.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 146.7;Esophageal apical cells: 425.7;Esophageal basal cells: 108.3;Esophageal suprabasal cells: 298.7;Ocular epithelial cells: 114.6;Salivary duct cells: 122.6;Smooth muscle cells: 134.8;Suprabasal keratinocytes: 254.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 425.7;Suprabasal cells: 298.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Smooth muscle cells, Skin - Keratinocyte (granular), Spleen - Smooth muscle cells" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 16.4;midbrain: 15.1;pons: 18.8;spinal cord: 56.8;thalamus: 21.4" "Cell type enriched" "Detected in many" "Keratinocytes: 449936998.0" "Tissue enhanced" "Detected in all" "lymphoid tissue: 211201627.3" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 400000 "Cluster 58: Skin - Keratinization" "Cluster 45: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 3 Cytosol "Plasma membrane" "HPA000878: , HPA002940: , HPA004145: , HPA020111: " "unprognostic (3.01e-2)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (7.60e-2)" "unprognostic (6.54e-3)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (1.10e-2)" "unprognostic (4.88e-2)" "unprognostic (3.45e-1)" "unprognostic (5.12e-2)" "unprognostic (8.28e-2)" "unprognostic (1.76e-1)" "unprognostic (7.65e-2)" "unprognostic (8.66e-3)" "potential prognostic unfavorable (1.13e-8)" "unprognostic (4.82e-2)" "unprognostic (2.08e-1)" "unprognostic (1.48e-2)" "unprognostic (1.21e-2)" "unprognostic (5.76e-3)" "potential prognostic unfavorable (6.60e-5)" "unprognostic (8.33e-3)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (4.27e-3)" "unprognostic (3.07e-1)" "unprognostic (8.62e-3)" "unprognostic (1.39e-1)" "unprognostic (1.39e-1)" "unprognostic (3.54e-2)" AIDA "C1orf80, FLJ12806" ENSG00000186063 "Axin interactor, dorsalization associated" Q96BJ3 1 222668013-222713210 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 67.8" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" HPA027935 Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 9 "Microtubules, Primary cilium" "Cytokinetic bridge, Basal body" "HPA027935: " "unprognostic (8.68e-3)" "unprognostic (1.61e-1)" "unprognostic (1.28e-1)" "unprognostic (1.47e-2)" "unprognostic (1.00e-1)" "unprognostic (1.54e-2)" "unprognostic (1.02e-1)" "unprognostic (5.13e-2)" "unprognostic (1.36e-2)" "unprognostic (2.09e-1)" "potential prognostic favorable (7.46e-5)" "unprognostic (7.30e-2)" "potential prognostic unfavorable (1.62e-5)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (1.05e-2)" "unprognostic (3.48e-2)" "unprognostic (1.63e-1)" "unprognostic (2.85e-2)" "unprognostic (6.24e-2)" "unprognostic (7.86e-3)" "unprognostic (1.81e-2)" "unprognostic (9.33e-2)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "unprognostic (1.94e-1)" "unprognostic (4.76e-2)" "unprognostic (8.39e-2)" "unprognostic (2.64e-1)" "unprognostic (1.27e-2)" "unprognostic (3.80e-2)" AIFM2 "AMID, FLJ14497, FSP1, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 191.6;Esophageal apical cells: 170.5;Late spermatids: 87.9" "Cell type enhanced" "Detected in many" "Adipocytes: 191.6;Apical squamous epithelial cells: 170.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" 7 Vesicles "Plasma membrane, Cytosol" "HPA028961: , HPA042309: , HPA075576: " "unprognostic (3.96e-1)" "unprognostic (4.07e-1)" "unprognostic (1.80e-1)" "unprognostic (3.62e-2)" "unprognostic (6.15e-2)" "unprognostic (4.43e-2)" "unprognostic (6.32e-3)" "unprognostic (2.89e-2)" "unprognostic (4.83e-2)" "unprognostic (3.30e-2)" "unprognostic (5.74e-2)" "unprognostic (1.11e-1)" "unprognostic (1.00e-2)" "potential prognostic unfavorable (9.87e-4)" "unprognostic (1.88e-1)" "unprognostic (6.32e-2)" "unprognostic (7.77e-2)" "unprognostic (1.31e-1)" "unprognostic (2.02e-1)" "unprognostic (9.57e-2)" "unprognostic (8.29e-2)" "unprognostic (1.55e-1)" "unprognostic (5.88e-2)" "unprognostic (1.34e-1)" "unprognostic (9.45e-2)" "unprognostic (3.27e-3)" "unprognostic (2.05e-1)" "unprognostic (1.11e-2)" "unprognostic (2.90e-1)" "unprognostic (1.00e-2)" "unprognostic (1.28e-2)" AIG1 "AIG-1, dJ95L4.1, FLJ10485" ENSG00000146416 "Androgen induced 1" Q9NVV5 6 143060496-143341058 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 220.0" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 527.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Distal tubules: 307234.9;Glomeruli: 440618.2;Hepatocytes: 236403.4;Proximal tubules: 631587.0" "Tissue enriched" "Detected in single" 192 "liver: 19213.4" HPA060766 Approved Uncertain "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 3 "Golgi apparatus" "HPA060766: " "unprognostic (6.92e-2)" "unprognostic (1.08e-3)" "unprognostic (8.96e-3)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (3.36e-2)" "unprognostic (2.79e-1)" "unprognostic (1.12e-3)" "unprognostic (6.49e-3)" "potential prognostic unfavorable (1.89e-7)" "potential prognostic unfavorable (9.38e-4)" "potential prognostic favorable (1.84e-8)" "unprognostic (3.95e-3)" "unprognostic (6.16e-2)" "unprognostic (5.24e-2)" "unprognostic (1.95e-2)" "unprognostic (1.17e-2)" "unprognostic (3.96e-2)" "unprognostic (1.14e-1)" "unprognostic (4.75e-2)" "unprognostic (1.86e-3)" "unprognostic (2.44e-2)" "unprognostic (1.12e-1)" "unprognostic (4.30e-3)" "unprognostic (3.02e-2)" "unprognostic (3.54e-2)" "unprognostic (4.84e-3)" "unprognostic (3.49e-2)" "unprognostic (3.47e-2)" "unprognostic (4.64e-2)" "unprognostic (2.79e-1)" "unprognostic (9.21e-2)" AK1 ENSG00000106992 "Adenylate kinase 1" P00568 9 127866486-127877675 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 522.7;skeletal muscle: 1262.8;tongue: 730.8" "Cell type enhanced" "Detected in many" "Colonocytes: 106.0;Ependymal cells: 324.9;Epididymal efferent duct ciliated cells: 1136.1;Fallopian tube ciliated cells: 197.7" "Cell type enriched" "Detected in many" 10 "Ciliated cells: 1136.1" "Cell type enriched" "Detected in all" 6 "ependymal cell: 580.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Cardiomyocytes: 624170068.0;Skeletal myofibers: 2276457325.7" "Group enriched" "Detected in all" "heart muscle: 930249157.2;skeletal muscle: 1650807628.7" "HPA006456, CAB009893" Enhanced Approved Cytosol,Annulus NA NA 10000000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 34: Ciliated cells - Cilia assembly & function" 5 Cytosol Annulus "CAB009893: , HPA006456: " "potential prognostic unfavorable (3.54e-4)" "unprognostic (4.48e-2)" "unprognostic (1.72e-1)" "unprognostic (1.18e-1)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (1.32e-1)" "unprognostic (5.69e-2)" "unprognostic (2.17e-1)" "unprognostic (4.59e-2)" "unprognostic (1.01e-2)" "unprognostic (7.64e-2)" "potential prognostic favorable (1.83e-8)" "unprognostic (6.32e-3)" "unprognostic (9.58e-2)" "unprognostic (1.18e-2)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (1.13e-1)" "unprognostic (3.25e-3)" "unprognostic (2.02e-2)" "unprognostic (1.09e-2)" "unprognostic (1.00e-1)" "unprognostic (1.14e-1)" "unprognostic (1.28e-1)" "unprognostic (5.16e-3)" "unprognostic (1.66e-1)" "unprognostic (4.36e-3)" "unprognostic (1.14e-1)" "unprognostic (2.37e-2)" "unprognostic (1.11e-1)" AK3 "AK3L1, AK6, AKL3L1" ENSG00000147853 "Adenylate kinase 3" Q9UIJ7 9 4709556-4742043 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Ligase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.6" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 411.6;Hepatocytes: 392.2;Parietal cells: 590.5;Syncytiotrophoblasts: 420.5" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 590.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "heart muscle: 250897249.2" HPA063324 Enhanced Supported Mitochondria NA NA 130000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 97: Non-specific - Cellular respiration" 12 Mitochondria "HPA063324: " "potential prognostic favorable (2.17e-4)" "unprognostic (7.18e-3)" "unprognostic (5.18e-2)" "unprognostic (6.18e-2)" "unprognostic (2.13e-1)" "unprognostic (3.71e-1)" "unprognostic (9.49e-2)" "unprognostic (1.01e-1)" "unprognostic (3.69e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (5.21e-7)" "unprognostic (3.76e-3)" "potential prognostic favorable (8.91e-4)" "unprognostic (3.51e-2)" "unprognostic (2.86e-2)" "unprognostic (1.24e-1)" "unprognostic (2.13e-1)" "unprognostic (9.16e-2)" "unprognostic (8.85e-2)" "unprognostic (4.22e-1)" "unprognostic (3.24e-2)" "unprognostic (8.28e-2)" "unprognostic (3.94e-2)" "unprognostic (2.41e-1)" "unprognostic (1.34e-2)" "unprognostic (2.40e-1)" "unprognostic (7.80e-2)" "unprognostic (1.08e-2)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" AK6 CINAP ENSG00000085231 "Adenylate kinase 6" Q9Y3D8 5 69350984-69370013 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 8 "Early spermatids: 158.5;Late spermatids: 379.8" "Cell type enriched" "Detected in many" 17 "Spermatogenic cell types: 379.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" "salivary gland: 7090819.6;Stomach: 23886986.4" "CAB005361, HPA070217" Supported Supported "Nuclear speckles,Centrosome" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 "Nuclear speckles" Centrosome "CAB005361: , HPA070217: " "unprognostic (2.05e-1)" "unprognostic (6.11e-2)" "unprognostic (4.95e-2)" "unprognostic (2.16e-1)" "unprognostic (3.15e-3)" "unprognostic (1.65e-1)" "unprognostic (7.87e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (5.33e-2)" "unprognostic (4.80e-2)" "unprognostic (7.16e-2)" "unprognostic (1.07e-2)" "unprognostic (2.39e-3)" "unprognostic (1.34e-1)" "unprognostic (9.20e-2)" "unprognostic (1.79e-1)" "unprognostic (9.97e-2)" "unprognostic (4.27e-3)" "unprognostic (4.97e-3)" "unprognostic (3.30e-2)" "unprognostic (1.50e-2)" "unprognostic (9.02e-2)" "unprognostic (3.62e-2)" "unprognostic (9.84e-2)" "unprognostic (1.00e-1)" "unprognostic (1.55e-1)" "unprognostic (7.01e-2)" "unprognostic (2.18e-1)" AK9 "AKD1, AKD2, C6orf199, C6orf224, dJ70A9.1, FLJ25791, FLJ42177, MGC26954" ENSG00000155085 "Adenylate kinase 9" Q5TCS8 6 109492855-109691217 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 212.1;Early primary spermatocytes: 252.9;Endometrial ciliated cells: 207.6;Ependymal cells: 354.1;Fallopian tube ciliated cells: 209.9;Respiratory ciliated cells: 519.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 519.8;Spermatogenic cell types: 252.9" "Cell type enhanced" "Detected in all" "ependymal cell: 370.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 273589 "Fallopian tube cells: 27358930.0" "Tissue enhanced" "Detected in all" "heart muscle: 73148969.1;Stomach: 93904454.8" "HPA030804, HPA030805, HPA031779, HPA031781, HPA036324, HPA036711" Enhanced Enhanced "Nucleoplasm,Nuclear membrane,Cytosol,Calyx" NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Nuclear membrane" "Cytosol, Calyx" "HPA030804: , HPA030805: , HPA031779: , HPA031781: , HPA036324: , HPA036711: " "unprognostic (7.67e-2)" "unprognostic (1.98e-3)" "unprognostic (1.17e-2)" "unprognostic (5.49e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (5.50e-1)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" "unprognostic (4.37e-2)" "unprognostic (8.65e-3)" "unprognostic (5.23e-3)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (9.62e-5)" "unprognostic (1.24e-2)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (3.86e-1)" "unprognostic (3.18e-1)" "potential prognostic favorable (4.39e-4)" "unprognostic (1.28e-3)" "unprognostic (2.01e-1)" "unprognostic (5.17e-3)" "unprognostic (2.74e-2)" "unprognostic (1.87e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (1.91e-1)" "unprognostic (1.62e-1)" AKAP10 "D-AKAP2, MGC9414, PRKA10" ENSG00000108599 "A-kinase anchoring protein 10" O43572 17 19904302-19978343 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 252.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 78.1" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "Stomach: 7116566.4" HPA028901 Approved Supported "Plasma membrane,Cytosol" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "Plasma membrane, Cytosol" "HPA028901: " "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (2.21e-1)" "unprognostic (2.67e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (3.28e-1)" "unprognostic (7.66e-2)" "unprognostic (1.60e-2)" "unprognostic (9.84e-3)" "potential prognostic favorable (1.29e-4)" "unprognostic (9.12e-3)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (1.79e-1)" "unprognostic (2.33e-1)" "unprognostic (1.74e-1)" "unprognostic (1.68e-1)" "unprognostic (1.82e-2)" "unprognostic (6.92e-2)" "unprognostic (2.21e-3)" "unprognostic (8.95e-2)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (9.04e-2)" "unprognostic (1.13e-1)" "unprognostic (5.74e-3)" "unprognostic (2.85e-2)" "unprognostic (7.07e-2)" "unprognostic (1.43e-1)" "unprognostic (7.06e-2)" "unprognostic (2.99e-1)" AKAP12 "AKAP250, SSeCKS" ENSG00000131016 "A-kinase anchoring protein 12" Q02952 6 151239967-151358559 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 750.0;Lymphatic endothelial cells: 1618.9;Melanocytes: 615.6;Müller glia: 1424.2;Ovarian stromal cells: 912.6;Pericytes: 619.1;Retinal ganglion cells: 571.7;Schwann cells: 958.6;Sertoli cells: 794.3;Smooth muscle cells: 885.7;Vascular endothelial cells: 657.5;Vascular smooth muscle cells: 684.3" "Cell type enhanced" "Detected in many" "Endothelial cells: 1618.9;Glial cells: 1424.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 70.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 236 "basophil: 37.3" "Lineage enriched" "Detected in single" 236 "granulocytes: 37.3" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 78219199.5;Microglia and Neuropil: 73843973.1;Oocytes: 56251868.7" "Tissue enhanced" "Detected in all" "ovary: 881233434.0" "HPA006344, CAB026379, HPA056230" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3700000 "Cluster 46: Basophils - Proteolysis" "Cluster 47: Testis - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 29 "Plasma membrane, Cytosol" "CAB026379: , HPA006344: , HPA056230: " "unprognostic (2.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.87e-3)" "unprognostic (2.09e-2)" "unprognostic (1.93e-2)" "unprognostic (4.09e-2)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-2)" "potential prognostic favorable (1.30e-6)" "unprognostic (1.10e-3)" "unprognostic (6.30e-2)" "unprognostic (8.48e-2)" "unprognostic (9.48e-3)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (2.54e-1)" "unprognostic (8.35e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (2.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.33e-2)" "unprognostic (5.75e-2)" "unprognostic (2.03e-1)" "unprognostic (2.14e-2)" "unprognostic (1.43e-1)" "unprognostic (4.18e-3)" "unprognostic (5.22e-1)" "unprognostic (3.54e-3)" "unprognostic (1.58e-1)" AKAP5 "AKAP75, AKAP79" ENSG00000179841 "A-kinase anchoring protein 5" P24588 14 64465499-64474503 "Plasma proteins, Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 17.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 15.9;Brain inhibitory neurons: 29.0;Cardiomyocytes: 28.2;Goblet cells: 35.9;Mast cells: 38.7;NK-cells: 30.0;Retinal ganglion cells: 15.5" "Cell type enhanced" "Detected in many" "Goblet cells: 35.9;Mast cells: 38.7;Myocytes: 28.2;Neuronal cells: 29.0;NK-cells: 30.0" "Cell type enhanced" "Detected in all" "medium spiny neuron: 66.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 2.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 2.9" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Group enriched" "Detected in all" 5 "amygdala: 27.6;basal ganglia: 79.0;cerebral cortex: 29.4;hippocampal formation: 30.8" "Group enriched" "Detected in all" 5 "amygdala: 32.3;basal ganglia: 105.6;cerebral cortex: 59.0;hippocampal formation: 57.6" "Group enriched" "Detected in some" 23633 "Astrocytes and Neuropil: 1265016.8;Microglia and Neuropil: 2156479.6;Neurons: 3668329.0" "Tissue enriched" "Detected in single" 58332 "cerebral cortex: 5833196.2" "CAB004308, HPA053891, HPA070486" Enhanced Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 20 "Golgi apparatus" "Plasma membrane, Cytosol" "CAB004308: , HPA053891: , HPA070486: " "unprognostic (4.53e-2)" "unprognostic (1.63e-1)" "unprognostic (1.56e-1)" "unprognostic (4.29e-1)" "unprognostic (1.56e-2)" "potential prognostic favorable (9.13e-4)" "unprognostic (1.87e-1)" "potential prognostic favorable (4.75e-5)" "unprognostic (1.11e-1)" "unprognostic (1.28e-1)" "unprognostic (3.01e-2)" "unprognostic (8.01e-2)" "unprognostic (1.94e-1)" "unprognostic (1.81e-1)" "unprognostic (9.00e-2)" "unprognostic (4.60e-3)" "unprognostic (1.61e-3)" "unprognostic (8.62e-3)" "unprognostic (1.63e-1)" "unprognostic (2.55e-1)" AKIRIN2 "C6orf166, dJ486L4.2, FLJ10342" ENSG00000135334 "Akirin 2" Q53H80 6 87674860-87702233 "Essential proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity, Protein transport, Transcription, Transcription regulation, Transport" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 530.7;Neutrophils: 509.5;Platelets: 701.0;Syncytiotrophoblasts: 267.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 530.7;Neutrophils: 509.5;Platelets: 701.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA064239 Supported Nucleoplasm No Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 32 Nucleoplasm "HPA064239: " "unprognostic (2.09e-1)" "unprognostic (2.05e-2)" "unprognostic (7.15e-2)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (2.36e-1)" "unprognostic (8.76e-3)" "unprognostic (1.36e-2)" "unprognostic (6.94e-2)" "unprognostic (5.83e-3)" "unprognostic (7.05e-2)" "unprognostic (1.05e-1)" "unprognostic (1.69e-1)" "unprognostic (6.55e-2)" "unprognostic (4.02e-2)" "unprognostic (4.39e-2)" "unprognostic (1.89e-1)" "unprognostic (5.03e-2)" "unprognostic (2.17e-1)" "unprognostic (4.74e-2)" "unprognostic (1.65e-3)" "unprognostic (1.31e-1)" "unprognostic (2.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "unprognostic (1.75e-1)" "unprognostic (5.11e-2)" "unprognostic (1.09e-2)" "unprognostic (1.01e-1)" AKNAD1 "C1orf62, MGC26989" ENSG00000162641 "AKNA domain containing 1" Q5T1N1 1 108815898-108963484 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.6" "Cell type enhanced" "Detected in many" "Astrocytes: 37.1;Bergmann glia: 62.2;Brain excitatory neurons: 27.5;Brain inhibitory neurons: 33.1;Choroid plexus epithelial cells: 27.0;Early spermatids: 225.0;Ependymal cells: 35.5;Late primary spermatocytes: 70.7;Late spermatids: 35.9;Oligodendrocyte progenitor cells: 52.3;Oligodendrocytes: 50.2" "Group enriched" "Detected in many" 4 "Glial cells: 62.2;Spermatogenic cell types: 225.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Bladder Urothelial Carcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030270, HPA030271, HPA030272" Uncertain Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 11: Neuronal - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Cytosol "Microtubules, Cytokinetic bridge" "HPA030270: , HPA030271: , HPA030272: " "unprognostic (1.18e-1)" "potential prognostic favorable (8.81e-4)" AKR1B1 "ALDR1, AR" ENSG00000085662 "Aldo-keto reductase family 1 member B" P15121 7 134442356-134459284 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "adrenal gland: 3016.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 909.6;Cytotrophoblasts: 1274.3;Extravillous trophoblasts: 1456.7;Hofbauer cells: 477.1;Migrating cytotrophoblasts: 1520.7;Oocytes: 686.2;Syncytiotrophoblasts: 2450.6" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 909.6;Oocytes: 686.2;Trophoblast cells: 2450.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 1445.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Oocytes: 522327534.1;Skeletal myofibers: 381413088.1" "Tissue enhanced" "Detected in all" "skeletal muscle: 283939045.7" "HPA026425, CAB027391, CAB047353, HPA052751" Enhanced Supported Nucleoplasm,Cytosol No No 1600000 "Cluster 39: T-cells - T-cell receptor" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Cytosol Nucleoplasm "CAB027391: , CAB047353: , HPA026425: , HPA052751: " "unprognostic (3.13e-3)" "unprognostic (9.62e-2)" "unprognostic (1.23e-1)" "unprognostic (2.93e-2)" "unprognostic (8.67e-2)" "unprognostic (2.05e-1)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (1.61e-3)" "unprognostic (2.98e-2)" "unprognostic (6.42e-2)" "unprognostic (2.21e-1)" "unprognostic (2.48e-2)" "unprognostic (1.32e-1)" "unprognostic (2.73e-1)" "unprognostic (2.18e-1)" "unprognostic (1.71e-2)" "unprognostic (1.06e-1)" "unprognostic (2.17e-1)" "unprognostic (1.70e-1)" "unprognostic (3.17e-2)" "unprognostic (3.89e-1)" "unprognostic (6.93e-2)" "unprognostic (2.53e-1)" "unprognostic (5.75e-2)" "unprognostic (2.89e-2)" "potential prognostic unfavorable (6.55e-6)" "unprognostic (2.72e-1)" "unprognostic (2.90e-2)" "unprognostic (1.25e-2)" AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 211.0;intestine: 577.8;stomach 1: 408.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 226.2;Cholangiocytes: 145.7;Colonocytes: 167.6;Enterocytes: 304.0;Esophageal apical cells: 141.7;Esophageal basal cells: 569.2;Esophageal suprabasal cells: 880.0;Foveolar cells: 853.4;Suprabasal keratinocytes: 496.9" "Group enriched" "Detected in many" 4 "Basal cells: 569.2;Enterocytes: 304.0;Gastric glandular cells: 853.4;Suprabasal cells: 880.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 484.3;Lung Squamous Cell Carcinoma (TCGA): 382.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Gallbladder cancer: 2714.5" "Colon - Colon enterocytes, Pituitary gland - Thyrotropes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Oocytes: 4078458.7" "Tissue enriched" "Detected in some" "intestine: 249251282.8" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" Enzyme NA NA 250000 "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 13 Cytosol "Plasma membrane" "CAB070163: , HPA020280: , HPA073633: " "unprognostic (5.66e-1)" "unprognostic (6.98e-3)" "unprognostic (2.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.27e-2)" "unprognostic (2.45e-1)" "unprognostic (1.80e-1)" "unprognostic (2.72e-1)" "validated prognostic unfavorable (5.83e-8)" "validated prognostic unfavorable (5.94e-4)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (1.67e-3)" "unprognostic (1.36e-1)" "unprognostic (2.15e-2)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (3.97e-2)" "unprognostic (2.39e-1)" "unprognostic (3.43e-3)" "unprognostic (4.07e-3)" "unprognostic (9.07e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (2.36e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-3)" "unprognostic (1.24e-1)" AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 156.9" "Cell type enhanced" "Detected in some" "Adipocytes: 3.0;Early spermatids: 3.3;Esophageal apical cells: 4.8;Esophageal suprabasal cells: 3.8;Granulosa cells: 3.2;Late spermatids: 5.9;Myonuclei: 2.6;Myosatellite cells: 8.0;Parietal cells: 3.5;Suprabasal keratinocytes: 6.3;Syncytiotrophoblasts: 26.8;Thymic myoid cells: 5.4" "Cell type enhanced" "Detected in some" "Stem cells: 8.0;Suprabasal cells: 6.3;Trophoblast cells: 26.8" "Cell type enhanced" "Detected in single" "committed oligodendrocyte precursor: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 7.3" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 10363 "intestine: 1036330.0" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 55: Breast - Lactation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 Cytosol "Plasma membrane" "HPA020280: , HPA073633: " "unprognostic (6.11e-3)" "unprognostic (1.97e-2)" "unprognostic (5.12e-1)" "unprognostic (1.39e-3)" "unprognostic (9.75e-3)" "unprognostic (3.52e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (1.57e-5)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (2.19e-1)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (8.94e-4)" "unprognostic (1.22e-1)" "unprognostic (1.09e-1)" "unprognostic (2.71e-1)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (1.24e-1)" "unprognostic (2.58e-1)" "unprognostic (1.57e-1)" "unprognostic (2.70e-1)" AKR1C1 "DD1, DDH, DDH1, HAKRC, MBAB" ENSG00000187134 "Aldo-keto reductase family 1 member C1" Q04828 10 4963253-4983283 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 581.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 195.1;Cholangiocytes: 337.7;Conjunctival goblet cells: 571.8;Esophageal basal cells: 191.7;Fibroblasts: 185.5;Foveolar cells: 323.8;Hepatocytes: 794.7;Ocular epithelial cells: 260.1;Respiratory secretory cells: 379.7;Suprabasal keratinocytes: 184.6;Urothelial cells: 343.8" "Cell type enhanced" "Detected in many" "Goblet cells: 571.8;Hepatocytes: 794.7;Secretory cells: 379.7" "Cell type enhanced" "Detected in many" "fibroblast: 81.0" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 650.3;Lung Squamous Cell Carcinoma (TCGA): 1045.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Esophageal cancer: 532.2;Gallbladder cancer: 872.6;liver cancer: 767.2" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells" "Cell type enriched" "Detected in single" 3406 "Hepatocytes: 340616.2" "Not detected" "Not detected" "CAB047303, HPA068265" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 3400000 "Cluster 41: Basophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 10 "Endoplasmic reticulum, Cytosol" "CAB047303: , HPA068265: " "unprognostic (2.01e-1)" "unprognostic (1.99e-2)" "unprognostic (3.00e-2)" "unprognostic (1.84e-2)" "unprognostic (1.27e-1)" "unprognostic (3.08e-2)" "unprognostic (4.03e-2)" "potential prognostic favorable (2.55e-4)" "unprognostic (9.85e-2)" "unprognostic (7.71e-2)" "potential prognostic favorable (3.12e-8)" "unprognostic (9.43e-2)" "unprognostic (4.26e-1)" "validated prognostic unfavorable (1.48e-4)" "validated prognostic unfavorable (3.42e-6)" "unprognostic (1.69e-1)" "unprognostic (3.75e-3)" "unprognostic (8.63e-2)" "unprognostic (5.59e-2)" "unprognostic (3.82e-2)" "unprognostic (8.97e-2)" "unprognostic (1.83e-1)" "unprognostic (1.22e-1)" "unprognostic (8.63e-3)" "unprognostic (1.40e-1)" "unprognostic (2.83e-1)" "unprognostic (1.77e-1)" "unprognostic (7.76e-2)" "unprognostic (2.12e-1)" "unprognostic (1.78e-2)" "unprognostic (3.07e-2)" AKR1C2 "BABP, DD, DD2, DDH2, HAKRD, MCDR2, TDD" ENSG00000151632 "Aldo-keto reductase family 1 member C2" P52895 10 4987775-5018031 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 316.8;liver: 448.7" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 715.5;Esophageal basal cells: 173.7;Foveolar cells: 332.8;Hepatocytes: 561.7;Ocular epithelial cells: 300.8;Prostatic hillock cells: 277.0;Respiratory secretory cells: 259.3;Salivary duct cells: 704.0;Suprabasal keratinocytes: 178.5;Urothelial cells: 919.4" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 919.4;Ductal cells: 704.0;Goblet cells: 715.5;Hepatocytes: 561.7" "Cell type enriched" "Detected in many" 8 "fibroblast: 183.3" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 964.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder cancer: 359.3;Esophageal cancer: 1222.9;Gallbladder cancer: 1184.3;liver cancer: 557.1;lung cancer: 433.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Gastric mucous cells, Testis - Peritubular cells" "Cell type enriched" "Detected in many" "Hepatocytes: 175244587.9" "Tissue enhanced" "Detected in many" "liver: 190935173.3" "CAB047304, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 3300000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 13 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB047304: , HPA068265: " "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (7.61e-2)" "unprognostic (9.47e-3)" "unprognostic (2.40e-2)" "unprognostic (4.82e-2)" "unprognostic (3.08e-1)" "unprognostic (5.99e-2)" "unprognostic (1.75e-2)" "unprognostic (2.86e-1)" "potential prognostic favorable (7.86e-6)" "unprognostic (1.17e-1)" "unprognostic (3.16e-2)" "unprognostic (7.97e-3)" "unprognostic (1.20e-1)" "unprognostic (7.17e-2)" "unprognostic (5.92e-2)" "unprognostic (3.34e-1)" "unprognostic (3.86e-1)" "unprognostic (1.46e-1)" "unprognostic (8.34e-2)" "unprognostic (3.96e-2)" "unprognostic (9.16e-3)" "unprognostic (3.91e-2)" "unprognostic (5.11e-2)" "unprognostic (1.71e-1)" "unprognostic (9.13e-2)" "unprognostic (1.34e-2)" "unprognostic (4.27e-2)" "unprognostic (1.58e-3)" "unprognostic (6.35e-3)" AKR1C3 "DDX, HAKRB, HSD17B5, KIAA0119, PGFS" ENSG00000196139 "Aldo-keto reductase family 1 member C3" P42330 10 5035354-5107686 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 415.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 290.7;Enteric transient amplifying cells: 265.8;Enterocytes: 515.0;Foveolar cells: 432.1;Hematopoietic stem cells: 200.4;Hepatocytes: 414.0;Urothelial cells: 388.5" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 388.5;Enterocytes: 515.0;Gastric glandular cells: 432.1;Hepatocytes: 414.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 603.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 244.9;gdT-cell: 102.8" "Group enriched" "Detected in many" 4 "granulocytes: 244.9;T-cells: 102.8" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1748.7" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells" "Group enriched" "Detected in many" "Glomeruli: 77698740.5;Hepatocytes: 155732840.6;Proximal tubules: 180219902.5" "Tissue enhanced" "Detected in all" "liver: 258071781.0" "CAB010874, HPA068265" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 2700000 "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 68: Foveolar cells - Mucosal defense" 10 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "CAB010874: , HPA068265: " "unprognostic (2.23e-1)" "unprognostic (1.52e-2)" "unprognostic (1.25e-1)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (7.08e-2)" "potential prognostic favorable (1.50e-4)" "unprognostic (1.86e-3)" "unprognostic (3.73e-1)" "potential prognostic favorable (8.42e-5)" "unprognostic (6.47e-2)" "potential prognostic unfavorable (3.70e-4)" "validated prognostic unfavorable (5.07e-6)" "validated prognostic unfavorable (2.51e-7)" "unprognostic (3.93e-2)" "unprognostic (2.97e-2)" "unprognostic (4.07e-2)" "unprognostic (1.51e-1)" "unprognostic (6.61e-2)" "unprognostic (1.21e-1)" "unprognostic (6.33e-2)" "unprognostic (2.69e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-1)" "unprognostic (3.97e-2)" "unprognostic (1.75e-1)" "unprognostic (3.68e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (3.50e-2)" AKR1C4 "3-alpha-HSD, C11, CDR, CHDR, DD4, HAKRA, MGC22581" ENSG00000198610 "Aldo-keto reductase family 1 member C4" P17516 10 5195462-5218949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "liver: 670.3" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 807.8" "Cell type enriched" "Detected in some" 27 "Hepatocytes: 807.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 87 "Liver Hepatocellular Carcinoma (TCGA): 254.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 4.1;colorectal cancer: 3.6;Gastric cancer: 1.8;liver cancer: 6.8" "Liver - Hepatocytes, Testis - Early spermatids" "Cell type enriched" "Detected in some" "Hepatocytes: 267166740.7" "Tissue enriched" "Detected in some" "liver: 130334228.7" "HPA044720, HPA068265" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Endoplasmic reticulum,Cytosol" NA NA 2500000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 7: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 4 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Endoplasmic reticulum" "HPA044720: , HPA068265: " "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (2.52e-5)" "unprognostic (4.54e-2)" "unprognostic (3.87e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-2)" "unprognostic (3.65e-2)" "unprognostic (5.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" AKR1D1 SRD5B1 ENSG00000122787 "Aldo-keto reductase family 1 member D1" P51857 7 138002324-138118305 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Oxidoreductase "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 82 "liver: 398.8" "Group enriched" "Detected in some" 4 "Early spermatids: 157.1;Hepatocytes: 306.0;Late spermatids: 374.7" "Group enriched" "Detected in many" 23 "Hepatocytes: 306.0;Spermatogenic cell types: 374.7" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in single" 53 "Liver Hepatocellular Carcinoma (TCGA): 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "liver cancer: 2.4" "Liver - Hepatocytes, Minor Salivary Gland - Plasma cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 165754207.1;Proximal tubules: 51184949.9" "Group enriched" "Detected in some" "liver: 48768077.0;Stomach: 67339478.8" HPA057002 Enhanced Approved Nucleoplasm,Cytosol No NA 130000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 5 Nucleoplasm Cytosol "HPA057002: " "potential prognostic favorable (8.12e-4)" "unprognostic (2.27e-3)" AKT1 "AKT, PKB, PRKBA, RAC, RAC-alpha" ENSG00000142208 "AKT serine/threonine kinase 1" P31749 14 104769349-104795751 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" "Apoptosis, Carbohydrate metabolism, Glucose metabolism, Glycogen biosynthesis, Glycogen metabolism, Neurogenesis, Sugar transport, Translation regulation, Transport" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 152.8" "Cell type enhanced" "Detected in many" "Secretory cells: 152.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 24.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "intestine: 5341759.1" "HPA002891, CAB003765, CAB080436" Supported Approved "Nucleoplasm,Microtubules,Primary cilium,Basal body,Perinuclear theca,Calyx,Principal piece,End piece" NA NA 7600 "Cluster 45: Eosinophils - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 43: Hindbrain - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 4: Breast lactating luminal cells - Lactation" 399 "Nucleoplasm, Microtubules, Principal piece, End piece" "Primary cilium, Basal body, Perinuclear theca, Calyx" "CAB003765: , CAB080436: , HPA002891: " "unprognostic (1.20e-1)" "unprognostic (1.22e-1)" "unprognostic (6.07e-2)" "unprognostic (3.52e-2)" "unprognostic (5.14e-2)" "unprognostic (2.32e-2)" "unprognostic (2.25e-1)" "unprognostic (6.34e-2)" "unprognostic (1.25e-2)" "unprognostic (2.91e-2)" "potential prognostic favorable (1.15e-4)" "unprognostic (1.19e-3)" "unprognostic (1.77e-3)" "potential prognostic unfavorable (7.84e-5)" "unprognostic (8.90e-2)" "unprognostic (2.68e-1)" "unprognostic (2.54e-1)" "unprognostic (6.96e-2)" "unprognostic (1.43e-1)" "unprognostic (2.84e-2)" "unprognostic (1.04e-1)" "unprognostic (9.22e-2)" "unprognostic (1.75e-1)" "unprognostic (1.38e-1)" "unprognostic (6.70e-2)" "unprognostic (3.27e-1)" "unprognostic (1.95e-2)" "unprognostic (1.23e-1)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (1.10e-1)" ALAS1 "ALAS, ALAS-H, ALAS3" ENSG00000023330 "5'-aminolevulinate synthase 1" P13196 3 52198086-52214327 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Heme biosynthesis" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 697.4;liver: 513.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 534.3;Esophageal apical cells: 140.4;Hepatocytes: 282.3;Syncytiotrophoblasts: 420.3;Urothelial cells: 168.3" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 534.3;Hepatocytes: 282.3;Trophoblast cells: 420.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 234.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 234.4" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 734834.6;Pancreas epithelial cells: 373667.0;Pancreatic islets: 1159165.5" "Tissue enriched" "Detected in some" "liver: 1831136.1" "CAB017498, HPA035860" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 76: Non-specific - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 18: Adrenal cortex cells - Steroidogensis" 44 Mitochondria Nucleoplasm "CAB017498: , HPA035860: " "potential prognostic favorable (3.69e-4)" "unprognostic (2.07e-1)" "unprognostic (4.36e-1)" "unprognostic (5.86e-2)" "unprognostic (9.93e-3)" "unprognostic (2.01e-1)" "unprognostic (1.23e-1)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.57e-2)" "unprognostic (1.76e-3)" "unprognostic (5.40e-2)" "unprognostic (8.32e-3)" "potential prognostic favorable (6.05e-5)" "unprognostic (1.34e-2)" "unprognostic (8.95e-2)" "unprognostic (5.16e-2)" "unprognostic (9.99e-2)" "unprognostic (9.54e-2)" "unprognostic (9.05e-3)" "unprognostic (1.51e-1)" "unprognostic (3.54e-2)" "unprognostic (8.88e-2)" "unprognostic (1.20e-1)" "unprognostic (1.26e-1)" "unprognostic (5.75e-2)" "unprognostic (1.55e-1)" "unprognostic (9.16e-2)" "unprognostic (3.08e-2)" "unprognostic (2.41e-1)" "unprognostic (9.73e-2)" ALDH18A1 "GSAS, P5CS, PYCS, SPG9" ENSG00000059573 "Aldehyde dehydrogenase 18 family member A1" P54886 10 95605941-95656711 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" "Kinase, Multifunctional enzyme, Oxidoreductase, Transferase" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 113.1" "Cell type enhanced" "Detected in many" "Salivary acinar cells: 153.5" "Cell type enhanced" "Detected in many" "Acinar cells: 153.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Pancreas epithelial cells: 249804164.7;Pancreatic islets: 152024337.2" "Group enriched" "Detected in many" "intestine: 63890118.3;pancreas: 137885626.3;salivary gland: 144886299.4" "HPA008333, HPA012604" Approved Enhanced Mitochondria NA NA 70000 "Cluster 24: Non-specific - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 25 Mitochondria "HPA008333: , HPA012604: " "unprognostic (7.54e-2)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (2.14e-1)" "unprognostic (1.02e-1)" "unprognostic (1.36e-1)" "unprognostic (5.49e-2)" "unprognostic (2.23e-2)" "potential prognostic favorable (4.32e-4)" "unprognostic (5.93e-2)" "unprognostic (7.26e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (8.73e-4)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (4.91e-4)" "unprognostic (8.93e-3)" "unprognostic (4.22e-2)" "potential prognostic unfavorable (8.95e-4)" "unprognostic (2.82e-2)" "unprognostic (4.17e-2)" "unprognostic (3.09e-1)" "unprognostic (3.48e-2)" "unprognostic (4.67e-2)" "unprognostic (5.74e-3)" "unprognostic (1.83e-1)" "unprognostic (1.52e-1)" "unprognostic (9.56e-2)" "unprognostic (3.79e-2)" "unprognostic (2.09e-3)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (1.88e-2)" ALDH1A1 "ALDH1, PUMB1, RALDH1" ENSG00000165092 "Aldehyde dehydrogenase 1 family member A1" P00352 9 72900671-73080442 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 1403.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 1199.3;Conjunctival goblet cells: 654.4;Hepatocytes: 876.5;Pancreatic islet cells: 684.9;Parietal cells: 2970.1;Respiratory ciliated cells: 714.3;Respiratory deuterosomal cells: 906.0;Respiratory secretory cells: 1138.0" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 2970.1;Glial cells: 1199.3" "Group enriched" "Detected in many" 5 "astrocyte: 398.2;Bergmann glia: 1353.3" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 745.7;Liver Hepatocellular Carcinoma (TCGA): 682.5" "Region enhanced" "Detected in all" "midbrain: 738.6" "Immune cell enriched" "Detected in many" 6 "classical monocyte: 87.5" "Lineage enriched" "Detected in many" 33 "monocytes: 87.5" "Cancer enhanced" "Detected in many" "liver cancer: 1023.3;Rhabdoid: 959.5;Sarcoma: 855.7" "Breast - Fibroblasts, Liver - Hepatocytes, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_2, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "midbrain: 494.1" "Cell type enhanced" "Detected in all" "Hepatocytes: 1621512379.1;Pancreas epithelial cells: 1253230164.5;Pancreatic islets: 1846472738.2" "Group enriched" "Detected in all" "intestine: 841554557.2;liver: 2178298988.1;pancreas: 2066952885.5" "HPA002123, CAB020690" Enhanced Approved Enhanced Cytosol NA NA 50000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 17 Cytosol "CAB020690: , HPA002123: " "unprognostic (6.73e-2)" "unprognostic (3.35e-2)" "unprognostic (4.78e-1)" "potential prognostic favorable (2.97e-4)" "unprognostic (2.09e-1)" "unprognostic (2.41e-1)" "unprognostic (1.99e-2)" "unprognostic (1.55e-1)" "unprognostic (1.47e-1)" "unprognostic (7.90e-2)" "potential prognostic favorable (4.89e-7)" "unprognostic (2.12e-1)" "unprognostic (5.02e-2)" "unprognostic (3.97e-2)" "unprognostic (9.15e-3)" "unprognostic (5.48e-2)" "unprognostic (2.19e-2)" "unprognostic (3.54e-3)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" "unprognostic (1.22e-1)" "unprognostic (3.22e-2)" "unprognostic (1.55e-2)" "unprognostic (4.32e-1)" "unprognostic (3.81e-2)" "unprognostic (1.43e-2)" "unprognostic (3.11e-2)" "unprognostic (1.95e-1)" "unprognostic (2.36e-1)" "unprognostic (1.19e-2)" "unprognostic (2.25e-1)" ALDH1A3 "ALDH6, RALDH3" ENSG00000184254 "Aldehyde dehydrogenase 1 family member A3" P47895 15 100877714-100916626 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 126.3;urinary bladder: 116.7" "Cell type enhanced" "Detected in many" "Breast lactating cells: 208.9;Breast secretory cells: 204.5;Decidual stromal cells: 204.0;Endometrial stromal cells: 231.1;Epicardial cells: 334.3;Lacrimal acinar cells: 469.2;Leydig cells: 263.5;Mesothelial cells: 219.2;Ocular epithelial cells: 381.7;Prostatic glandular cells: 215.7;Retinal pigment epithelial cells: 315.5;Salivary acinar cells: 408.7;Salivary basal cells: 273.3;Salivary duct cells: 670.9;Salivary ionocytes: 226.5;Urothelial cells: 467.8" "Cell type enhanced" "Detected in many" "Acinar cells: 469.2;Barrier epithelial cells: 467.8;Ductal cells: 670.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 27.0;fibroblast: 24.1;oligodendrocyte precursor cell: 37.8" "Group enriched" "Detected in all" 6 "Prostate Adenocarcinoma (TCGA): 310.1;Skin Cutaneous Melanoma (TCGA): 78.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "pancreatic cancer: 420.2" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "olfactory bulb: 6.0;spinal cord: 20.7" "Cell type enriched" "Detected in many" "Large ducts: 7470271.2" "Low tissue specificity" "Detected in many" "HPA046271, HPA064749" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 2 Nucleoplasm Cytosol "HPA046271: , HPA064749: " "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (2.55e-1)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "unprognostic (9.30e-3)" "unprognostic (1.37e-1)" "unprognostic (8.38e-2)" "unprognostic (2.84e-3)" "unprognostic (2.39e-1)" "unprognostic (1.83e-3)" "unprognostic (1.32e-1)" "unprognostic (1.61e-3)" "unprognostic (1.12e-1)" "unprognostic (1.42e-3)" "unprognostic (6.41e-2)" "unprognostic (1.55e-3)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (3.94e-5)" "unprognostic (8.92e-2)" "unprognostic (9.34e-2)" "unprognostic (2.54e-1)" "unprognostic (9.11e-2)" "unprognostic (1.10e-2)" "unprognostic (2.63e-1)" "unprognostic (2.38e-2)" "unprognostic (9.95e-2)" "unprognostic (2.04e-1)" "unprognostic (2.90e-1)" ALDH1B1 "ALDH5, ALDHX" ENSG00000137124 "Aldehyde dehydrogenase 1 family member B1" P30837 9 38392702-38398661 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 138.0;liver: 161.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 93.1;Enteric stem cells: 139.6;Enteric transient amplifying cells: 51.5;Extravillous trophoblasts: 61.1;Hepatic stellate cells: 45.2;Hepatocytes: 156.0;Paneth cells: 123.8;Smooth muscle cells: 184.0" "Cell type enhanced" "Detected in many" "Ductal cells: 93.1;Hepatocytes: 156.0;Secretory gland support: 123.8;Smooth muscle cells: 184.0;Stem cells: 139.6" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 7.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 163145412.6;Proximal tubules: 247749679.4;Smooth muscle cells: 160911799.0" "Tissue enhanced" "Detected in all" "liver: 106345810.1" "HPA021037, HPA077080" Enhanced Supported Mitochondria NA NA 320000 "Cluster 33: Non-specific - ATP binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 45: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 62: Smooth muscle cells - Muscle contraction" 19 Mitochondria "HPA021037: , HPA077080: " "unprognostic (3.51e-2)" "unprognostic (2.55e-1)" "unprognostic (1.77e-1)" "unprognostic (4.37e-3)" "unprognostic (2.13e-2)" "unprognostic (1.72e-1)" "unprognostic (4.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-3)" "unprognostic (1.56e-1)" "potential prognostic favorable (4.96e-5)" "unprognostic (6.57e-3)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (2.67e-3)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (6.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.09e-3)" "unprognostic (6.23e-2)" "unprognostic (3.43e-1)" "unprognostic (2.87e-3)" "unprognostic (3.76e-1)" "unprognostic (2.37e-1)" "unprognostic (7.16e-2)" "unprognostic (5.16e-2)" "unprognostic (3.88e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (2.64e-6)" "unprognostic (8.27e-3)" ALDH1L1 "10-fTHF, FDH, FTHFD" ENSG00000144908 "Aldehyde dehydrogenase 1 family member L1" O75891 3 126103562-126197994 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 345.7" "Cell type enhanced" "Detected in many" "Adipocytes: 183.8;Astrocytes: 167.1;Bergmann glia: 262.8;Breast lactating cells: 199.5;Hepatocytes: 1030.6;Lacrimal acinar cells: 176.6;Proximal tubule cells: 316.1;Salivary acinar cells: 180.8" "Cell type enhanced" "Detected in many" "Glial cells: 262.8;Hepatocytes: 1030.6;Renal nephron cells: 316.1" "Group enriched" "Detected in many" 5 "astrocyte: 192.7;Bergmann glia: 281.3" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 224.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 16.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 283678929.3;Hepatocytes: 1111111536.2;Proximal tubules: 454836041.1" "Tissue enriched" "Detected in all" "liver: 1770350854.5" "HPA036900, HPA050139" Enhanced Supported Supported Cytosol No No 4500000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 93: Hepatocytes - Bile production & excretion" 5 Cytosol "HPA036900: , HPA050139: " "unprognostic (3.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.45e-3)" "unprognostic (2.50e-1)" "unprognostic (7.67e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (4.33e-3)" "unprognostic (1.12e-1)" "unprognostic (4.06e-1)" "potential prognostic favorable (2.78e-7)" "unprognostic (3.44e-3)" "unprognostic (2.60e-2)" "unprognostic (1.08e-1)" "unprognostic (3.01e-2)" "unprognostic (3.86e-1)" "unprognostic (3.78e-1)" "unprognostic (5.09e-2)" "unprognostic (4.64e-2)" "unprognostic (8.55e-2)" "unprognostic (1.25e-2)" "unprognostic (1.90e-3)" "unprognostic (1.01e-1)" "unprognostic (9.81e-2)" "unprognostic (1.90e-1)" "unprognostic (1.64e-3)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (1.76e-1)" ALDH1L2 "FLJ38508, mtFDH" ENSG00000136010 "Aldehyde dehydrogenase 1 family member L2" Q3SY69 12 105019784-105107643 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "pancreas: 38.3;salivary gland: 12.2" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 70.1;Gonadotrophs: 64.8;Pancreatic acinar cells: 107.4;Pituitary stem cells: 61.8;Plasma cells: 74.7;Retinal ganglion cells: 46.4;Salivary acinar cells: 43.1" "Cell type enhanced" "Detected in many" "Acinar cells: 107.4;Fibro-adipogenic progenitors: 70.1;Plasma cells: 74.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 39.5" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 575364097.7;Pancreas epithelial cells: 548253034.9" "Tissue enriched" "Detected in all" "liver: 926386744.3" "HPA039481, HPA059282" Approved Supported Mitochondria No No "Cluster 8: Pancreas - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 44: Plasma cells - Antibody production & secretion" 4 Mitochondria "HPA039481: , HPA059282: " "unprognostic (1.58e-3)" "unprognostic (2.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.66e-1)" "unprognostic (1.82e-1)" "unprognostic (1.51e-1)" "unprognostic (9.10e-2)" "unprognostic (5.31e-2)" "unprognostic (7.96e-2)" "unprognostic (1.37e-3)" "unprognostic (4.56e-2)" "unprognostic (1.80e-1)" "unprognostic (4.26e-2)" "unprognostic (4.98e-2)" "unprognostic (2.59e-1)" "unprognostic (1.02e-1)" "unprognostic (1.43e-3)" "unprognostic (1.18e-1)" "unprognostic (1.75e-1)" "unprognostic (6.91e-3)" "unprognostic (4.13e-2)" "unprognostic (2.56e-1)" "unprognostic (1.45e-2)" "unprognostic (1.38e-1)" "unprognostic (9.37e-2)" ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 504.2;salivary gland: 117.1;stomach 1: 212.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 427.0;Conjunctival goblet cells: 1071.8;Esophageal apical cells: 1402.6;Esophageal basal cells: 645.5;Esophageal suprabasal cells: 1716.4;Ocular epithelial cells: 2180.5;Respiratory basal cells: 441.1;Respiratory secretory cells: 387.4;Suprabasal keratinocytes: 751.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 1402.6;Barrier epithelial cells: 2180.5;Basal cells: 645.5;Goblet cells: 1071.8;Suprabasal cells: 1716.4" "Group enriched" "Detected in some" 15 "choroid plexus epithelial cell: 10.1;ependymal cell: 18.6" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 220.0;Lung Squamous Cell Carcinoma (TCGA): 332.4" "Region enriched" "Detected in many" 8 "choroid plexus: 35.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Gallbladder cancer: 3329.2" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Keratinocytes: 82254106.0" "Tissue enhanced" "Detected in many" "skin: 17185634.9" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 70000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 27 "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: , HPA051150: , HPA063783: " "unprognostic (3.66e-2)" "potential prognostic favorable (5.12e-5)" "unprognostic (4.35e-2)" "unprognostic (1.86e-2)" "unprognostic (4.51e-2)" "unprognostic (1.12e-1)" "unprognostic (6.93e-3)" "potential prognostic favorable (8.42e-5)" "unprognostic (8.26e-3)" "unprognostic (1.94e-1)" "unprognostic (1.67e-3)" "unprognostic (2.90e-1)" "unprognostic (1.75e-1)" "unprognostic (2.74e-1)" "unprognostic (2.01e-3)" "unprognostic (5.16e-2)" "unprognostic (2.76e-1)" "unprognostic (3.34e-2)" "unprognostic (7.25e-2)" "unprognostic (3.08e-3)" "unprognostic (6.54e-3)" "unprognostic (5.69e-2)" "unprognostic (1.96e-1)" "unprognostic (1.02e-3)" "unprognostic (1.24e-1)" "unprognostic (8.37e-2)" "unprognostic (3.13e-2)" "unprognostic (1.06e-1)" ALDH3A2 "ALDH10, FALDH, SLS" ENSG00000072210 "Aldehyde dehydrogenase 3 family member A2" P51648 17 19648136-19685760 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 269.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 277.6;Alveolar cells type 1: 297.2;Esophageal apical cells: 341.0;Esophageal basal cells: 250.4;Esophageal suprabasal cells: 252.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Keratinocyte (other), Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172766362.3;Proximal tubules: 150993221.5" "Tissue enhanced" "Detected in all" "liver: 148994703.0" "HPA014769, CAB020692" Enhanced Approved "Endoplasmic reticulum,Cytosol" NA NA 67000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 26: Keratinocytes - Keratinization" 21 "Endoplasmic reticulum, Cytosol" "CAB020692: , HPA014769: " "unprognostic (1.40e-1)" "unprognostic (4.91e-2)" "unprognostic (1.57e-2)" "unprognostic (2.64e-1)" "unprognostic (2.03e-2)" "unprognostic (8.42e-2)" "unprognostic (3.76e-1)" "unprognostic (8.54e-2)" "unprognostic (1.79e-1)" "unprognostic (1.24e-2)" "validated prognostic favorable (1.15e-10)" "validated prognostic favorable (4.77e-4)" "unprognostic (2.44e-3)" "unprognostic (1.86e-1)" "unprognostic (2.67e-2)" "unprognostic (8.65e-2)" "unprognostic (8.34e-2)" "unprognostic (1.73e-1)" "unprognostic (1.31e-1)" "unprognostic (2.13e-2)" "unprognostic (1.55e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (5.95e-2)" "unprognostic (1.81e-1)" "unprognostic (4.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.61e-3)" "unprognostic (2.02e-1)" "unprognostic (1.69e-1)" "potential prognostic favorable (2.59e-4)" ALDH4A1 "ALDH4, P5CDh" ENSG00000159423 "Aldehyde dehydrogenase 4 family member A1" P30038 1 18871430-18902724 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Proline metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 204.2;liver: 438.6" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 448.7" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 448.7" "Cell type enhanced" "Detected in all" "astrocyte: 37.6;choroid plexus epithelial cell: 46.6" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 140.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubules: 2553989929.6" "Group enriched" "Detected in all" "kidney: 437575308.2;liver: 857693272.6" "CAB004645, HPA006401, HPA072759" Enhanced Supported Mitochondria NA NA 82000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 70: DU4475 - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 18 Mitochondria "CAB004645: , HPA006401: , HPA072759: " "unprognostic (5.65e-3)" "unprognostic (6.15e-2)" "unprognostic (5.95e-3)" "unprognostic (3.01e-2)" "unprognostic (1.49e-2)" "unprognostic (1.37e-1)" "unprognostic (2.80e-1)" "unprognostic (8.91e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (1.29e-5)" "unprognostic (5.17e-2)" "potential prognostic favorable (1.39e-4)" "unprognostic (3.18e-2)" "unprognostic (3.08e-3)" "unprognostic (2.05e-2)" "unprognostic (2.51e-1)" "unprognostic (1.92e-1)" "unprognostic (1.36e-1)" "unprognostic (5.06e-2)" "unprognostic (1.17e-1)" "unprognostic (1.60e-1)" "unprognostic (2.59e-2)" "unprognostic (1.95e-1)" "unprognostic (2.38e-1)" "unprognostic (6.06e-2)" "unprognostic (2.21e-1)" "unprognostic (1.33e-1)" "unprognostic (4.59e-1)" "unprognostic (2.54e-3)" "unprognostic (4.90e-2)" ALDH5A1 "SSADH, SSDH" ENSG00000112294 "Aldehyde dehydrogenase 5 family member A1" P51649 6 24494867-24537207 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 92.3" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 62.9;Hepatocytes: 116.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 116.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "lymphoma: 51.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 193906621.2" "Group enriched" "Detected in all" "cerebral cortex: 145903310.2;liver: 161241726.3" "HPA029715, HPA029716" Enhanced Supported Mitochondria NA NA 87000 "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 6 Mitochondria "HPA029715: , HPA029716: " "unprognostic (9.37e-3)" "unprognostic (3.47e-1)" "unprognostic (2.70e-1)" "unprognostic (6.38e-2)" "unprognostic (2.05e-1)" "unprognostic (1.39e-2)" "unprognostic (4.97e-1)" "unprognostic (1.83e-1)" "unprognostic (1.59e-1)" "unprognostic (1.76e-1)" "validated prognostic favorable (1.00e-6)" "validated prognostic favorable (9.16e-5)" "unprognostic (1.23e-1)" "potential prognostic favorable (5.56e-4)" "unprognostic (2.15e-3)" "unprognostic (5.06e-2)" "unprognostic (2.11e-2)" "unprognostic (4.56e-2)" "unprognostic (8.86e-3)" "unprognostic (1.68e-3)" "unprognostic (1.37e-1)" "unprognostic (1.23e-2)" "unprognostic (3.56e-2)" "unprognostic (2.08e-1)" "unprognostic (1.54e-2)" "unprognostic (2.56e-1)" "unprognostic (2.89e-2)" "unprognostic (1.59e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-1)" "unprognostic (2.60e-1)" ALDH6A1 MMSDH ENSG00000119711 "Aldehyde dehydrogenase 6 family member A1" Q02252 14 74056847-74084492 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "kidney: 353.5;liver: 342.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 630.8;Parietal cells: 213.9;Proximal tubule cells: 141.5;Retinal pigment epithelial cells: 162.0" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 213.9;Hepatocytes: 630.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 43.2" "Lineage enriched" "Detected in all" 4 "granulocytes: 43.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_2, Stomach - Parietal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubules: 3092894915.3" "Tissue enhanced" "Detected in all" "liver: 787681983.6" "HPA029072, HPA029073, HPA029074, HPA029075" Enhanced Enhanced Mitochondria No No 44000 "Cluster 41: Basophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 1 Mitochondria "HPA029072: , HPA029073: , HPA029074: , HPA029075: " "unprognostic (6.72e-2)" "unprognostic (1.61e-1)" "unprognostic (4.28e-1)" "unprognostic (6.76e-2)" "unprognostic (3.53e-2)" "unprognostic (1.04e-1)" "unprognostic (3.76e-2)" "unprognostic (2.16e-1)" "unprognostic (3.37e-1)" "unprognostic (1.06e-1)" "validated prognostic favorable (6.38e-11)" "validated prognostic favorable (1.97e-4)" "potential prognostic favorable (2.45e-4)" "unprognostic (3.74e-3)" "unprognostic (9.27e-2)" "unprognostic (1.57e-3)" "unprognostic (1.66e-1)" "unprognostic (2.59e-1)" "unprognostic (3.11e-1)" "unprognostic (2.30e-1)" "unprognostic (3.38e-3)" "unprognostic (4.12e-1)" "unprognostic (5.36e-2)" "unprognostic (1.39e-1)" "unprognostic (1.90e-2)" "unprognostic (2.82e-3)" "unprognostic (5.65e-2)" "unprognostic (4.75e-2)" "unprognostic (1.65e-1)" "unprognostic (1.21e-3)" "unprognostic (1.83e-2)" ALDH7A1 "ATQ1, EPD, PDE" ENSG00000164904 "Aldehyde dehydrogenase 7 family member A1" P49419 5 126531200-126595362 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 151.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 792.4;Migrating cytotrophoblasts: 388.0;Ovarian stromal cells: 327.3;Syncytiotrophoblasts: 258.9" "Cell type enhanced" "Detected in all" "Trophoblast cells: 792.4" "Cell type enhanced" "Detected in all" "astrocyte: 240.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.3" "Lineage enriched" "Detected in many" 5 "dendritic cells: 6.3" "Cancer enhanced" "Detected in all" "Rhabdoid: 301.3" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubules: 1292737222.5" "Tissue enhanced" "Detected in all" "liver: 413888163.8" "HPA023296, HPA053675" Enhanced Supported Mitochondria,Cytosol Yes No 750000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Mitochondria Cytosol "HPA023296: , HPA053675: " "unprognostic (1.60e-2)" "unprognostic (7.77e-2)" "unprognostic (7.23e-2)" "unprognostic (4.49e-2)" "unprognostic (2.17e-2)" "unprognostic (8.81e-3)" "unprognostic (1.05e-1)" "unprognostic (8.18e-3)" "unprognostic (1.28e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (2.87e-12)" "unprognostic (1.68e-2)" "unprognostic (6.78e-2)" "unprognostic (1.53e-3)" "unprognostic (1.05e-3)" "unprognostic (1.19e-1)" "unprognostic (7.19e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (1.96e-2)" "unprognostic (3.61e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (6.45e-4)" "unprognostic (1.32e-1)" "unprognostic (4.04e-1)" "unprognostic (5.85e-3)" "unprognostic (8.06e-2)" "unprognostic (3.74e-1)" "unprognostic (2.28e-1)" "unprognostic (3.72e-2)" "unprognostic (1.63e-2)" "unprognostic (6.32e-2)" ALDH9A1 "ALDH4, ALDH7, ALDH9, E3" ENSG00000143149 "Aldehyde dehydrogenase 9 family member A1" P49189 1 165662216-165698562 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 298.0;Esophageal apical cells: 786.4;Esophageal suprabasal cells: 428.5;Müller glia: 273.5;Retinal pigment epithelial cells: 225.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 786.4;Suprabasal cells: 428.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA006077, HPA010873" Approved Approved Cytosol "Intracellular and membrane" Enzyme NA NA 3200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 85: Squamous epithelial cells - Keratinization" 4 Cytosol "HPA006077: , HPA010873: " "unprognostic (1.97e-1)" "unprognostic (2.46e-1)" "unprognostic (7.64e-2)" "unprognostic (2.17e-1)" "unprognostic (1.52e-1)" "unprognostic (1.43e-2)" "unprognostic (5.95e-2)" "unprognostic (2.79e-3)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (5.31e-4)" "potential prognostic favorable (2.64e-7)" "unprognostic (1.18e-2)" "unprognostic (1.07e-1)" "unprognostic (4.88e-2)" "unprognostic (1.67e-3)" "unprognostic (1.10e-1)" "unprognostic (9.90e-2)" "unprognostic (2.32e-1)" "unprognostic (1.06e-1)" "unprognostic (8.35e-2)" "unprognostic (1.77e-1)" "validated prognostic favorable (8.54e-4)" "validated prognostic favorable (4.40e-4)" "unprognostic (6.85e-2)" "unprognostic (3.19e-1)" "unprognostic (2.40e-2)" "unprognostic (8.03e-2)" "unprognostic (3.08e-1)" "unprognostic (1.35e-2)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" ALDOA ENSG00000149925 "Aldolase, fructose-bisphosphate A" P04075 16 30064164-30070457 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes, Disease variant, Glycogen storage disease, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 25093.7;tongue: 8554.2" "Cell type enhanced" "Detected in many" "Astrocytes: 79.9;Bergmann glia: 100.2;Brain excitatory neurons: 129.7;Brain inhibitory neurons: 120.9;Choroid plexus epithelial cells: 52.6;Ependymal cells: 83.8;Microglia: 42.5;Oligodendrocyte progenitor cells: 51.4;Oligodendrocytes: 83.6;Other brain neurons: 204.3" "Group enriched" "Detected in many" 7 "Ciliated cells: 83.8;Glial cells: 100.2;Neuronal cells: 204.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Skeletal myofibers: 7032092911.5" "Group enriched" "Detected in all" "cerebral cortex: 3237968566.0;heart muscle: 3344452925.7;skeletal muscle: 11421921844.1" "HPA004177, CAB006252" Supported Approved Cytosol NA NA 310000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 40 Cytosol "CAB006252: , HPA004177: " "unprognostic (3.48e-3)" "unprognostic (2.04e-2)" "unprognostic (3.71e-2)" "unprognostic (1.30e-2)" "unprognostic (9.58e-2)" "unprognostic (6.58e-2)" "unprognostic (4.23e-3)" "unprognostic (1.08e-1)" "unprognostic (5.89e-3)" "unprognostic (5.50e-2)" "potential prognostic favorable (4.52e-4)" "unprognostic (4.66e-2)" "unprognostic (3.20e-1)" "validated prognostic unfavorable (4.48e-6)" "validated prognostic unfavorable (7.80e-6)" "validated prognostic unfavorable (1.56e-6)" "validated prognostic unfavorable (7.09e-4)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (8.15e-2)" "unprognostic (1.38e-1)" "unprognostic (1.77e-3)" "unprognostic (4.30e-1)" "unprognostic (5.49e-2)" "unprognostic (1.39e-1)" "unprognostic (9.27e-2)" "unprognostic (1.98e-1)" "unprognostic (2.32e-1)" "unprognostic (7.76e-2)" "unprognostic (2.76e-2)" "unprognostic (1.02e-2)" ALDOC ENSG00000109107 "Aldolase, fructose-bisphosphate C" P09972 17 28573115-28576948 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 1156.4;retina: 1098.1" "Group enriched" "Detected in some" 4 "Astrocytes: 106.1;Bergmann glia: 87.7;Brain excitatory neurons: 33.9;Brain inhibitory neurons: 38.7;Oligodendrocyte progenitor cells: 46.2;Other brain neurons: 45.4" "Group enriched" "Detected in some" 6 "Glial cells: 106.1;Neuronal cells: 45.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 421.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 475303107.9;Microglia and Neuropil: 378144316.8" "Group enriched" "Detected in all" "cerebral cortex: 1791367502.1;heart muscle: 646761005.3" "HPA003282, CAB020828, HPA067442" Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" Yes No 56000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 8 "Nucleoplasm, Nucleoli fibrillar center" "Vesicles, Cytosol" "CAB020828: , HPA003282: , HPA067442: " "unprognostic (1.09e-1)" "unprognostic (1.00e-1)" "unprognostic (1.43e-1)" "unprognostic (4.88e-3)" "unprognostic (6.11e-2)" "unprognostic (2.05e-1)" "unprognostic (2.18e-1)" "potential prognostic favorable (2.98e-4)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (2.13e-3)" "unprognostic (3.70e-3)" "unprognostic (2.26e-2)" "unprognostic (2.85e-3)" "unprognostic (1.01e-1)" "unprognostic (5.82e-2)" "unprognostic (4.02e-2)" "unprognostic (7.39e-2)" "unprognostic (1.56e-2)" "unprognostic (5.37e-2)" "unprognostic (1.92e-3)" "unprognostic (1.09e-1)" "unprognostic (3.32e-1)" "unprognostic (3.88e-1)" "unprognostic (7.09e-3)" "unprognostic (5.11e-1)" "unprognostic (2.64e-1)" "unprognostic (1.33e-1)" "unprognostic (5.57e-2)" "unprognostic (2.73e-1)" "unprognostic (4.58e-2)" "unprognostic (1.23e-2)" ALG10 "ALG10A, DIE2, FLJ14751" ENSG00000139133 "ALG10 alpha-1,2-glucosyltransferase" Q5BKT4 12 34022468-34029694 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 14.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Group enriched" "Detected in some" 16376 "B-cells: 1315252.0;Fallopian tube cells: 1123411.3;Granulosa cells: 869141.6;Neutrophils: 3439275.5;Pancreas epithelial cells: 1441156.7" "Tissue enriched" "Detected in single" 2435 "lymphoid tissue: 243534.3" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 9 "Endoplasmic reticulum" "HPA043329: , HPA063387: " "unprognostic (1.14e-1)" "unprognostic (6.06e-3)" "unprognostic (1.09e-1)" "unprognostic (2.37e-1)" "unprognostic (1.31e-2)" "unprognostic (3.15e-1)" "unprognostic (5.50e-1)" "unprognostic (4.93e-1)" "unprognostic (1.94e-1)" "unprognostic (3.71e-2)" "potential prognostic favorable (1.70e-6)" "unprognostic (1.05e-1)" "unprognostic (3.99e-1)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (6.46e-2)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (7.03e-2)" "unprognostic (2.27e-2)" "unprognostic (1.36e-2)" "unprognostic (6.51e-2)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (6.97e-2)" "potential prognostic favorable (1.88e-5)" "unprognostic (9.16e-2)" "unprognostic (7.39e-2)" "unprognostic (4.49e-2)" "unprognostic (1.22e-1)" "unprognostic (2.85e-1)" "unprognostic (2.16e-1)" ALG10B KCR1 ENSG00000175548 "ALG10 alpha-1,2-glucosyltransferase B" Q5I7T1 12 38316762-38329721 "Enzymes, Essential proteins, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Cell type enriched" "Detected in single" 321878 "Neurons: 32187820.0" "Not detected" "Not detected" "HPA043329, HPA063387" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 "Endoplasmic reticulum" "HPA043329: , HPA063387: " "unprognostic (4.98e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-1)" "unprognostic (1.07e-2)" "unprognostic (2.13e-2)" "unprognostic (5.45e-2)" "unprognostic (3.85e-1)" "unprognostic (2.54e-1)" "unprognostic (1.93e-1)" "unprognostic (1.48e-2)" "potential prognostic favorable (6.77e-4)" "unprognostic (9.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.62e-3)" "unprognostic (3.50e-2)" "unprognostic (8.18e-2)" "unprognostic (1.21e-3)" "unprognostic (4.17e-2)" "unprognostic (9.89e-2)" "unprognostic (1.26e-1)" "unprognostic (8.89e-2)" "unprognostic (1.39e-2)" "unprognostic (1.41e-2)" "unprognostic (6.21e-2)" "unprognostic (1.42e-3)" "unprognostic (1.45e-2)" "unprognostic (6.48e-2)" "unprognostic (6.75e-2)" "unprognostic (1.40e-1)" "unprognostic (6.42e-2)" "unprognostic (8.95e-2)" ALG13 "CDG1S, CXorf45, FLJ23018, GLT28D1, MDS031, TDRD13, YGL047W" ENSG00000101901 "ALG13 UDP-N-acetylglucosaminyltransferase subunit" Q9NP73 X 111665811-111760649 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Glycosyltransferase, Hydrolase, Multifunctional enzyme, Protease, Thiol protease, Transferase" "Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 342.5;Somatotrophs: 356.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 3181518.6" "Tissue enhanced" "Detected in many" "Stomach: 9251041.5" "HPA002853, HPA005498" Approved Approved Vesicles,Cytosol NA NA 26000000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 36: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 7 Vesicles Cytosol "HPA002853: , HPA005498: " "unprognostic (5.80e-2)" "unprognostic (9.52e-3)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (6.88e-2)" "unprognostic (6.13e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (1.49e-3)" "potential prognostic favorable (1.39e-4)" "unprognostic (2.14e-2)" "unprognostic (1.48e-1)" "unprognostic (1.69e-1)" "unprognostic (3.42e-2)" "unprognostic (1.09e-1)" "unprognostic (2.99e-2)" "unprognostic (1.83e-2)" "unprognostic (2.56e-1)" "unprognostic (4.75e-3)" "unprognostic (8.20e-2)" "unprognostic (2.30e-1)" "unprognostic (2.70e-2)" "unprognostic (5.39e-2)" "unprognostic (9.56e-3)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (5.62e-2)" "unprognostic (1.09e-1)" "unprognostic (2.43e-1)" "unprognostic (1.93e-1)" ALG5 bA421P11.2 ENSG00000120697 "ALG5 dolichyl-phosphate beta-glucosyltransferase" Q9Y673 13 36949738-37000763 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 237.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 71038380.3" "Tissue enhanced" "Detected in many" "Stomach: 21056786.2" HPA007989 Approved Approved Cytosol No No "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" Cytosol "HPA007989: " "unprognostic (2.07e-2)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (6.22e-2)" "unprognostic (2.62e-2)" "unprognostic (2.47e-1)" "unprognostic (9.45e-2)" "unprognostic (3.30e-3)" "potential prognostic unfavorable (3.49e-5)" "unprognostic (2.82e-1)" "potential prognostic favorable (2.56e-10)" "unprognostic (6.98e-3)" "unprognostic (1.13e-2)" "unprognostic (1.96e-2)" "unprognostic (2.74e-2)" "unprognostic (1.60e-2)" "unprognostic (4.26e-1)" "unprognostic (1.61e-1)" "unprognostic (1.27e-1)" "unprognostic (5.94e-2)" "unprognostic (1.76e-2)" "unprognostic (8.17e-2)" "unprognostic (2.35e-2)" "unprognostic (2.20e-1)" "unprognostic (4.81e-2)" "unprognostic (4.68e-2)" "unprognostic (2.09e-2)" "unprognostic (1.80e-1)" "unprognostic (1.67e-1)" "unprognostic (1.63e-2)" "unprognostic (1.82e-2)" ALPL "HOPS, TNALP, TNAP, TNSALP" ENSG00000162551 "Alkaline phosphatase, biomineralization associated" P05186 1 21509397-21578410 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Biomineralization Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 57.7" "Group enriched" "Detected in many" 5 "Alveolar cells type 2: 811.1;Neutrophils: 1574.3" "Group enriched" "Detected in many" 7 "Alveolar cells: 811.1;Neutrophils: 1574.3" "Cell type enriched" "Detected in many" 7 "endothelial cell: 166.4" "Cancer enriched" "Detected in all" 4 "Testicular Germ Cell Tumor (TCGA): 292.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 90 "neutrophil: 381.2" "Lineage enriched" "Detected in many" 139 "granulocytes: 381.2" "Cancer enhanced" "Detected in many" "Bone cancer: 75.0;testis cancer: 44.3" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Macrophages, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 2763560.9" "Low tissue specificity" "Detected in all" "HPA007105, HPA008765, CAB020829" Enhanced Approved Cytosol "Intracellular and membrane" Enzyme NA NA 9400000 "Cluster 4: Neutrophils - Degranulation" "Cluster 5: Spleen - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Cytosol "CAB020829: , HPA007105: , HPA008765: " "unprognostic (7.68e-2)" "unprognostic (4.91e-2)" "unprognostic (1.50e-1)" "unprognostic (1.14e-2)" "unprognostic (9.58e-2)" "unprognostic (5.72e-2)" "unprognostic (1.37e-3)" "unprognostic (2.75e-1)" "unprognostic (2.21e-2)" "unprognostic (2.40e-3)" "validated prognostic favorable (3.12e-4)" "validated prognostic favorable (5.51e-5)" "unprognostic (1.29e-1)" "unprognostic (5.58e-3)" "potential prognostic favorable (1.20e-4)" "unprognostic (4.70e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (2.22e-4)" "unprognostic (7.24e-2)" "unprognostic (5.17e-2)" "unprognostic (2.43e-2)" "unprognostic (1.03e-2)" "unprognostic (2.30e-1)" "unprognostic (2.40e-1)" "unprognostic (9.49e-2)" "unprognostic (1.28e-1)" "unprognostic (9.06e-2)" "unprognostic (1.42e-2)" "unprognostic (1.72e-1)" "unprognostic (6.75e-3)" "unprognostic (4.14e-2)" AMBP "EDC1, HCP, HI30, IATIL, ITI, ITIL, ITILC, UTI" ENSG00000106927 "Alpha-1-microglobulin/bikunin precursor" P02760 9 114060127-114078328 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Host-virus interaction" "Oxidoreductase, Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 68 "liver: 10227.4" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 12897.0" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 12897.0" "Cell type enriched" "Detected in some" 7 "ependymal cell: 10.4" "Cancer enriched" "Detected in many" 107 "Liver Hepatocellular Carcinoma (TCGA): 5486.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "liver cancer: 556.5" "Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 197262467.3" "Tissue enhanced" "Detected in all" "blood vessel: 243720262.4" "HPA001497, CAB069436, HPA075585" Approved Approved "Golgi apparatus,Vesicles,Cytosol" "Secreted to blood" Enzyme NA NA 3300000000 29000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 Vesicles "Golgi apparatus, Cytosol" "CAB069436: , HPA001497: , HPA075585: " "unprognostic (3.63e-3)" "unprognostic (8.63e-2)" "unprognostic (8.75e-3)" "unprognostic (2.74e-1)" "unprognostic (4.05e-2)" "unprognostic (3.78e-3)" "unprognostic (1.56e-1)" "unprognostic (2.52e-3)" "unprognostic (6.70e-3)" "unprognostic (2.61e-2)" "unprognostic (1.08e-2)" "unprognostic (3.21e-1)" "unprognostic (3.34e-2)" "unprognostic (8.16e-3)" "unprognostic (1.81e-1)" "unprognostic (2.85e-2)" "unprognostic (2.78e-1)" "unprognostic (4.70e-1)" "unprognostic (1.25e-3)" "unprognostic (5.63e-2)" "unprognostic (4.35e-1)" AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943331-95968720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 58.4;skeletal muscle: 25.4" "Group enriched" "Detected in many" 13 "Adrenal cortex cells: 85.4;Hepatocytes: 186.3" "Group enriched" "Detected in many" 13 "Adrenal endocrine cells: 85.4;Hepatocytes: 186.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 185.6;Testicular Germ Cell Tumor (TCGA): 319.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Esophageal cancer: 59.8;head and neck cancer: 65.1" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Hepatocytes: 38916883.8" "Tissue enriched" "Detected in some" "liver: 31964359.7" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 1800000 "Cluster 45: Eosinophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 3 Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: , HPA040149: " "unprognostic (8.45e-2)" "unprognostic (9.44e-2)" "unprognostic (2.03e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (2.13e-1)" "unprognostic (2.04e-1)" "unprognostic (3.00e-2)" "unprognostic (2.21e-1)" "unprognostic (8.33e-3)" "unprognostic (9.77e-2)" "unprognostic (1.49e-3)" "unprognostic (1.27e-1)" "unprognostic (7.93e-2)" "unprognostic (3.63e-3)" "unprognostic (4.19e-2)" "unprognostic (2.66e-1)" "unprognostic (2.70e-2)" "unprognostic (4.99e-2)" "unprognostic (6.26e-2)" "unprognostic (9.47e-2)" "potential prognostic favorable (8.03e-4)" "unprognostic (2.70e-3)" "unprognostic (4.03e-2)" "unprognostic (2.82e-3)" "potential prognostic favorable (1.11e-4)" "unprognostic (3.55e-1)" "unprognostic (4.07e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (2.70e-1)" AMDHD2 CGI-14 ENSG00000162066 "Amidohydrolase domain containing 2" Q9Y303 16 2520357-2531422 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 52.0;Enterocytes: 54.9;Hofbauer cells: 223.4;Kupffer cells: 69.7;Late primary spermatocytes: 129.2" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 223.4;Spermatogenic cell types: 129.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 9877395.6;Proximal tubules: 12574663.5" "Low tissue specificity" "Detected in many" "HPA041184, HPA041321" Enhanced Approved Nucleoli,Cytosol No No 65000 "Cluster 29: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Nucleoli, Cytosol" "HPA041184: , HPA041321: " "unprognostic (1.73e-1)" "unprognostic (1.73e-2)" "unprognostic (1.55e-1)" "unprognostic (5.44e-3)" "unprognostic (2.06e-3)" "unprognostic (5.70e-2)" "unprognostic (1.78e-2)" "unprognostic (1.78e-1)" "unprognostic (4.96e-2)" "unprognostic (1.91e-1)" "unprognostic (1.24e-3)" "unprognostic (2.80e-1)" "unprognostic (3.83e-3)" "unprognostic (2.91e-3)" "unprognostic (5.61e-2)" "unprognostic (1.06e-1)" "unprognostic (2.24e-1)" "unprognostic (1.18e-1)" "unprognostic (5.83e-2)" "unprognostic (1.26e-1)" "unprognostic (2.71e-1)" "unprognostic (3.99e-3)" "unprognostic (7.06e-3)" "unprognostic (2.13e-1)" "unprognostic (6.88e-2)" "unprognostic (6.64e-2)" "unprognostic (1.19e-1)" "unprognostic (3.04e-2)" "unprognostic (9.90e-3)" "unprognostic (4.04e-2)" "unprognostic (1.59e-1)" AMHR2 "MISR2, MISRII" ENSG00000135409 "Anti-Mullerian hormone receptor type 2" Q16671 12 53423855-53431672 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, Pseudohermaphroditism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 38.9;ovary: 32.4" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 52.5;Granulosa cells: 142.7;Mast cells: 20.5;Megakaryocyte-Erythroid progenitors: 9.7;Ovarian stromal cells: 26.9;Sertoli cells: 25.3" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 52.5;Reproductive supporting cells: 142.7;Stromal cells: 26.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.2" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Leukemia: 5.0;liver cancer: 4.7" "Adipose subcutaneous - Mast cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Colon - Mast cells, Liver - Sinusoid Endothelial cells, Pancreas - Exocrine glandular cells, Skin - Mast cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in some" 10 "hippocampal formation: 13.5" "Group enriched" "Detected in some" 4241 "Granulosa cells: 666130.8;Oocytes: 182091.7" "Not detected" "Not detected" "HPA060228, HPA069636" Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 21 Vesicles "Nucleoplasm, Cytosol" "HPA060228: , HPA069636: " "unprognostic (4.03e-2)" "unprognostic (3.07e-1)" AMPD2 SPG63 ENSG00000116337 "Adenosine monophosphate deaminase 2" Q01433 1 109616104-109632051 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 68.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 95.7;monocytes: 63.4;Neutrophils: 79.6" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 95.7;Neutrophils: 79.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 19.4;eosinophil: 19.3;intermediate monocyte: 40.7;myeloid DC: 18.9;neutrophil: 61.2;non-classical monocyte: 44.8" "Group enriched" "Detected in all" 5 "dendritic cells: 18.9;granulocytes: 61.2;monocytes: 44.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA027137, HPA045760" Approved Approved Cytosol NA NA 160000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 8 Cytosol "HPA027137: , HPA045760: " "unprognostic (2.88e-2)" "unprognostic (1.59e-2)" "unprognostic (4.52e-2)" "unprognostic (2.03e-1)" "unprognostic (4.83e-3)" "unprognostic (1.16e-2)" "unprognostic (1.21e-1)" "unprognostic (2.65e-3)" "unprognostic (3.98e-3)" "unprognostic (3.83e-2)" "unprognostic (8.77e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-1)" "unprognostic (7.72e-3)" "unprognostic (2.61e-1)" "unprognostic (4.96e-2)" "unprognostic (1.50e-2)" "unprognostic (1.97e-1)" "unprognostic (6.10e-2)" "unprognostic (6.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (9.13e-2)" "unprognostic (1.24e-1)" "unprognostic (3.81e-1)" "unprognostic (5.90e-2)" "unprognostic (3.91e-1)" "unprognostic (8.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" "unprognostic (1.70e-1)" AMPD3 ENSG00000133805 "Adenosine monophosphate deaminase 3" Q01432 11 10308313-10507579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 56.8;skeletal muscle: 61.1" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 181.7;Gonadotrophs: 203.2;Neutrophil progenitors: 228.6;Neutrophils: 186.9;Ocular epithelial cells: 149.4;Thymic myoid cells: 161.8;Thyrotrophs: 151.1" "Cell type enhanced" "Detected in many" "Neutrophils: 228.6;Pituitary endocrine cells: 203.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 119.2;committed oligodendrocyte precursor: 95.8;oligodendrocyte: 129.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 10891694.0;Macrophages: 10416894.3;Neutrophils: 17252370.0" "Group enriched" "Detected in many" "bone marrow: 15794129.1;lymphoid tissue: 14553921.3" "HPA038662, HPA047408" Uncertain Approved "Nuclear membrane,Nucleoli" NA NA 51000 "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 "Nuclear membrane" Nucleoli "HPA038662: , HPA047408: " "unprognostic (1.83e-1)" "unprognostic (6.73e-2)" "unprognostic (1.13e-2)" "unprognostic (9.78e-2)" "unprognostic (8.33e-3)" "unprognostic (2.33e-1)" "unprognostic (1.32e-2)" "unprognostic (1.93e-1)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (7.98e-4)" "unprognostic (1.78e-1)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (3.73e-3)" "unprognostic (1.83e-1)" "unprognostic (1.27e-1)" "unprognostic (4.50e-2)" "unprognostic (2.80e-2)" "unprognostic (2.82e-3)" "unprognostic (1.38e-1)" "unprognostic (8.13e-2)" "unprognostic (3.97e-2)" "unprognostic (1.77e-2)" "unprognostic (3.76e-1)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (2.25e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-2)" "unprognostic (2.47e-1)" "unprognostic (5.97e-2)" ANAPC11 "APC11, Apc11p, HSPC214, MGC882" ENSG00000141552 "Anaphase promoting complex subunit 11" Q9NYG5 17 81890790-81900991 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 766.4;Extravillous trophoblasts: 655.6;Late primary spermatocytes: 854.1;Late spermatids: 1837.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1837.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021989, HPA027838" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 30 Nucleoplasm Nucleoli "HPA021989: , HPA027838: " "unprognostic (1.54e-1)" "unprognostic (6.29e-2)" "unprognostic (5.96e-2)" "unprognostic (9.72e-3)" "unprognostic (6.73e-2)" "unprognostic (4.17e-2)" "unprognostic (7.63e-2)" "unprognostic (2.46e-1)" "unprognostic (8.56e-2)" "unprognostic (1.17e-2)" "unprognostic (5.01e-2)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (9.71e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (2.98e-9)" "unprognostic (4.79e-2)" "unprognostic (3.34e-2)" "unprognostic (5.29e-2)" "unprognostic (1.75e-1)" "unprognostic (8.77e-3)" "unprognostic (8.13e-2)" "unprognostic (1.41e-1)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (4.28e-1)" "unprognostic (1.44e-2)" "unprognostic (8.15e-2)" "unprognostic (9.24e-2)" "unprognostic (1.28e-1)" "unprognostic (1.02e-1)" "unprognostic (1.83e-1)" ANAPC2 "APC2, KIAA1406" ENSG00000176248 "Anaphase promoting complex subunit 2" Q9UJX6 9 137174784-137188560 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 39.3;Late primary spermatocytes: 57.1;Late spermatids: 85.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 85.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "bone marrow: 2359575.2;cerebral cortex: 759532.5;lymphoid tissue: 721869.1" "CAB018692, HPA066539" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 91 Nucleoplasm Mitochondria "CAB018692: , HPA066539: " "unprognostic (2.15e-1)" "unprognostic (1.72e-2)" "unprognostic (9.02e-2)" "potential prognostic favorable (3.48e-4)" "unprognostic (7.15e-2)" "unprognostic (3.94e-2)" "unprognostic (2.82e-1)" "unprognostic (1.35e-3)" "unprognostic (2.10e-2)" "unprognostic (1.25e-1)" "potential prognostic favorable (7.32e-7)" "unprognostic (1.50e-2)" "potential prognostic favorable (4.04e-4)" "unprognostic (2.78e-1)" "unprognostic (1.77e-1)" "unprognostic (8.78e-2)" "unprognostic (2.67e-1)" "unprognostic (6.57e-2)" "unprognostic (9.69e-2)" "unprognostic (2.06e-1)" "unprognostic (3.03e-2)" "potential prognostic favorable (1.23e-4)" "unprognostic (7.17e-2)" "unprognostic (1.73e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (3.07e-4)" "unprognostic (8.55e-2)" "unprognostic (1.04e-2)" "unprognostic (4.12e-2)" "unprognostic (6.17e-3)" "unprognostic (1.23e-2)" ANAPC7 APC7 ENSG00000196510 "Anaphase promoting complex subunit 7" Q9UJX3 12 110372900-110403730 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 87.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 824579.0" "CAB009567, HPA070008" Approved Supported "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 56 "Microtubules, Cytokinetic bridge, Mitotic spindle" "Nucleoplasm, Vesicles" "CAB009567: , HPA070008: " "unprognostic (1.91e-1)" "unprognostic (8.81e-3)" "unprognostic (2.11e-1)" "unprognostic (1.75e-1)" "unprognostic (7.60e-3)" "unprognostic (6.91e-2)" "unprognostic (2.82e-1)" "unprognostic (4.25e-3)" "unprognostic (3.00e-1)" "unprognostic (1.52e-3)" "potential prognostic favorable (6.27e-4)" "unprognostic (1.45e-1)" "unprognostic (6.89e-2)" "potential prognostic unfavorable (1.30e-7)" "unprognostic (1.02e-3)" "unprognostic (1.26e-3)" "unprognostic (1.97e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-3)" "unprognostic (1.69e-1)" "unprognostic (3.93e-1)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (3.55e-2)" "unprognostic (3.53e-1)" "unprognostic (1.47e-1)" "unprognostic (2.08e-1)" "unprognostic (1.95e-1)" "unprognostic (5.56e-2)" "unprognostic (1.21e-1)" "unprognostic (7.38e-3)" ANG "RAA1, RNASE5" ENSG00000214274 Angiogenin P03950 14 20684177-20698971 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Angiogenesis, Differentiation, Stress response" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Protein synthesis inhibitor" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 50 "liver: 2816.4" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 28.6" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 28.6" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 16 "Liver Hepatocellular Carcinoma (TCGA): 832.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 24.6;myeloid DC: 14.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 9301799.2;Smooth muscle cells: 13648080.2" "Tissue enriched" "Detected in many" "blood vessel: 36948837.1" HPA055896 Approved "Nucleoli,Nucleoli rim,Mitotic chromosome,Actin filaments" "Secreted to blood" "Developmental protein" Yes No 308000000 290000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 8 "Nucleoli, Nucleoli rim, Mitotic chromosome" "Actin filaments" "HPA055896: " "unprognostic (1.19e-1)" "unprognostic (3.18e-1)" "unprognostic (3.94e-2)" "unprognostic (2.67e-2)" "unprognostic (1.24e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (1.03e-2)" "unprognostic (6.63e-2)" "unprognostic (3.33e-2)" "validated prognostic favorable (3.36e-5)" "validated prognostic favorable (1.49e-5)" "unprognostic (3.77e-2)" "validated prognostic favorable (6.44e-5)" "validated prognostic favorable (5.12e-4)" "unprognostic (7.07e-2)" "unprognostic (2.40e-1)" "unprognostic (4.10e-2)" "unprognostic (1.98e-1)" "unprognostic (9.17e-2)" "unprognostic (1.14e-1)" "unprognostic (2.95e-1)" "unprognostic (1.50e-2)" "unprognostic (3.32e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (5.52e-7)" "unprognostic (4.00e-2)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "unprognostic (8.43e-2)" "unprognostic (5.96e-2)" ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 118.1;skeletal muscle: 120.2" "Cell type enhanced" "Detected in many" "Astrocytes: 1654.3;Bergmann glia: 6456.2;Brain excitatory neurons: 1399.6;Brain inhibitory neurons: 1228.1;Ependymal cells: 1554.5;Myonuclei: 1069.4;Oligodendrocytes: 1582.7;Other brain neurons: 1483.3;Retinal ganglion cells: 2151.6;Retinal horizontal cells: 2652.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 1554.5;Glial cells: 6456.2;Neuronal cells: 2652.5" "Cell type enhanced" "Detected in all" "Bergmann glia: 6675.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 51.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 43.8;Rhabdoid: 31.6" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 423361422.4;Microglia and Neuropil: 520244937.1;Neurons: 144516326.2" "Tissue enriched" "Detected in many" "cerebral cortex: 871796207.5" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane,Acrosome" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 40 "Plasma membrane, Acrosome" "CAB015178: , HPA008007: , HPA035970: " "unprognostic (8.16e-2)" "unprognostic (1.58e-1)" "unprognostic (1.54e-3)" "potential prognostic favorable (7.08e-5)" "unprognostic (7.10e-2)" "unprognostic (3.36e-2)" "unprognostic (1.63e-1)" "unprognostic (1.97e-1)" "unprognostic (3.34e-1)" "unprognostic (3.43e-1)" "unprognostic (1.17e-1)" "unprognostic (9.71e-2)" "unprognostic (4.03e-3)" "unprognostic (1.78e-1)" "unprognostic (1.22e-3)" "unprognostic (6.01e-2)" "potential prognostic unfavorable (3.78e-4)" "unprognostic (2.16e-1)" "unprognostic (6.28e-2)" "unprognostic (1.64e-1)" "unprognostic (1.46e-3)" "unprognostic (2.10e-1)" "unprognostic (4.04e-2)" "unprognostic (5.85e-2)" "unprognostic (3.74e-2)" "unprognostic (5.89e-2)" "unprognostic (3.48e-3)" "unprognostic (1.75e-1)" "unprognostic (1.23e-3)" "unprognostic (3.31e-2)" ANKRD11 "ANCO-1, ANCO1, LZ16, T13" ENSG00000167522 "Ankyrin repeat domain containing 11" Q6UB99 16 89267630-89490561 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1162.3" "Cell type enhanced" "Detected in all" "Neutrophils: 1162.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 3862804.7" "Tissue enriched" "Detected in some" "bone marrow: 16549292.1" "CAB019288, HPA041593, HPA049470" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 19 Nucleoplasm Cytosol "CAB019288: , HPA041593: , HPA049470: " "unprognostic (2.87e-1)" "unprognostic (1.61e-1)" "unprognostic (3.23e-2)" "unprognostic (1.61e-1)" "unprognostic (3.84e-2)" "unprognostic (6.86e-2)" "unprognostic (3.24e-1)" "unprognostic (8.47e-2)" "unprognostic (6.48e-2)" "unprognostic (2.31e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (3.66e-6)" "unprognostic (1.75e-1)" "unprognostic (2.60e-3)" "unprognostic (8.97e-3)" "unprognostic (6.10e-2)" "unprognostic (1.55e-2)" "unprognostic (1.76e-1)" "unprognostic (2.87e-1)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (4.17e-5)" "unprognostic (9.33e-3)" "unprognostic (1.45e-1)" "unprognostic (4.75e-2)" "unprognostic (6.00e-2)" "unprognostic (4.88e-1)" "unprognostic (4.03e-2)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" ANKRD13A "ANKRD13, NY-REN-25" ENSG00000076513 "Ankyrin repeat domain 13A" Q8IZ07 12 109999186-110039763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 258.2;Neutrophil progenitors: 229.4;Neutrophils: 571.7" "Cell type enhanced" "Detected in many" "Neutrophils: 571.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 10640159.6" "Tissue enhanced" "Detected in many" "lymphoid tissue: 130030946.3" "HPA039488, HPA043218" Enhanced Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Primary cilium transition zone" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 41 "Plasma membrane" "Vesicles, Primary cilium, Primary cilium tip, Primary cilium transition zone" "HPA039488: , HPA043218: " "unprognostic (1.48e-1)" "unprognostic (9.99e-3)" "unprognostic (8.13e-2)" "unprognostic (1.11e-1)" "unprognostic (5.70e-2)" "unprognostic (3.02e-1)" "unprognostic (1.89e-1)" "unprognostic (1.49e-3)" "unprognostic (6.64e-3)" "potential prognostic unfavorable (6.22e-4)" "potential prognostic favorable (4.43e-8)" "unprognostic (3.40e-2)" "unprognostic (2.03e-2)" "unprognostic (2.43e-1)" "unprognostic (9.95e-2)" "unprognostic (8.33e-3)" "unprognostic (7.25e-2)" "unprognostic (1.35e-3)" "unprognostic (2.85e-1)" "unprognostic (6.02e-3)" "unprognostic (1.47e-2)" "unprognostic (5.75e-2)" "unprognostic (1.71e-1)" "unprognostic (3.76e-2)" "unprognostic (1.24e-1)" "unprognostic (4.99e-2)" "unprognostic (3.30e-1)" "unprognostic (1.99e-1)" "unprognostic (4.98e-1)" "unprognostic (1.99e-1)" "unprognostic (1.88e-3)" ANKRD17 "FLJ22206, GTAR, KIAA0697, MASK2, NY-BR-16" ENSG00000132466 "Ankyrin repeat domain 17" O75179 4 73073376-73258798 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA045024, HPA063731" Approved Supported "Nucleoplasm,Nuclear membrane" No No "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 27 Nucleoplasm "Nuclear membrane" "HPA045024: , HPA063731: " "unprognostic (1.23e-1)" "unprognostic (5.19e-2)" "unprognostic (4.79e-1)" "unprognostic (1.73e-3)" "unprognostic (5.29e-2)" "unprognostic (1.89e-1)" "unprognostic (2.56e-2)" "unprognostic (8.83e-2)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (1.69e-4)" "validated prognostic favorable (1.29e-5)" "validated prognostic favorable (8.03e-4)" "unprognostic (3.33e-1)" "unprognostic (2.51e-3)" "unprognostic (1.18e-1)" "unprognostic (4.24e-2)" "unprognostic (7.03e-2)" "unprognostic (5.14e-2)" "unprognostic (8.36e-2)" "unprognostic (1.10e-1)" "unprognostic (2.92e-1)" "unprognostic (2.01e-2)" "unprognostic (2.41e-2)" "unprognostic (8.49e-2)" "unprognostic (6.50e-2)" "unprognostic (2.22e-2)" "unprognostic (9.49e-2)" "unprognostic (1.34e-1)" "unprognostic (2.12e-1)" "unprognostic (1.98e-2)" "unprognostic (2.43e-1)" ANKRD20A1 "ANKRD20A, DKFZp434A171" ENSG00000260691 "Ankyrin repeat domain 20 family member A1" Q5TYW2 9 67832765-67920552 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 3.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 13.8;Early primary spermatocytes: 24.6;Oligodendrocyte progenitor cells: 11.8;Undifferentiated spermatogonia: 62.4" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 62.4" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043239, HPA046346, HPA046695, HPA047112, HPA047167, HPA047766, HPA049923, HPA051288, HPA051753, HPA054389" Uncertain Approved Nucleoplasm NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Nucleoplasm "HPA043239: , HPA046346: , HPA046695: , HPA047112: , HPA047167: , HPA047766: , HPA049923: , HPA051288: , HPA051753: , HPA054389: " ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 58.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 38.7;Endometrial ciliated cells: 91.9;Esophageal apical cells: 113.4;Esophageal suprabasal cells: 68.6;Fibroblasts: 36.9;Lacrimal acinar cells: 35.3;Müller glia: 33.9;Peritubular myoid cells: 40.6;Respiratory secretory cells: 40.5;Suprabasal keratinocytes: 44.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 113.4;Ciliated cells: 91.9;Suprabasal cells: 68.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Leukemia: 1.3" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatocytes, Pancreas - Fibroblasts, Skin - Keratinocyte (other), Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Keratinocytes: 23055848.0" "Not detected" "Not detected" HPA035453 Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 108: Fibroblasts - ECM organization" 3 "Plasma membrane" "Nucleoplasm, Vesicles, Primary cilium, Primary cilium transition zone, Basal body" "HPA035453: " "unprognostic (1.72e-2)" "unprognostic (2.03e-2)" "potential prognostic favorable (5.60e-4)" "unprognostic (1.10e-2)" "unprognostic (3.11e-2)" "unprognostic (5.06e-2)" "unprognostic (6.53e-3)" "unprognostic (1.31e-1)" "unprognostic (3.46e-2)" "unprognostic (3.79e-1)" "unprognostic (2.81e-1)" "unprognostic (4.20e-2)" "unprognostic (1.12e-2)" "unprognostic (1.81e-1)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (1.35e-2)" "unprognostic (2.37e-1)" "unprognostic (7.56e-2)" ANKRD36 UNQ2430 ENSG00000135976 "Ankyrin repeat domain 36" A6QL64 2 97113153-97264521 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 18.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 354.7;Brain inhibitory neurons: 393.7;Oligodendrocytes: 258.0" "Cell type enhanced" "Detected in all" "Neuronal cells: 393.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 264 "heart muscle: 26385.3" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 37: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 6 "Nucleoplasm, Cytosol" "HPA051757: , HPA057661: " "unprognostic (3.16e-2)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (4.09e-5)" "unprognostic (9.27e-2)" "unprognostic (7.46e-2)" "unprognostic (2.74e-2)" "unprognostic (1.04e-2)" "unprognostic (1.95e-2)" "unprognostic (2.19e-1)" "unprognostic (2.80e-1)" "unprognostic (5.19e-2)" "unprognostic (9.65e-2)" "unprognostic (9.07e-3)" "unprognostic (3.08e-2)" "unprognostic (9.65e-2)" "unprognostic (2.00e-1)" "unprognostic (1.31e-1)" "unprognostic (8.75e-2)" "potential prognostic unfavorable (7.37e-4)" "unprognostic (8.86e-3)" "unprognostic (4.21e-3)" "unprognostic (4.13e-2)" "unprognostic (1.64e-1)" "unprognostic (9.99e-3)" ANKRD36B "FLJ21281, KIAA1641" ENSG00000196912 "Ankyrin repeat domain 36B" Q8N2N9 2 97492663-97589877 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 115.1;Sertoli cells: 198.2;Thyrotrophs: 128.7" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 198.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 114 "lymphoid tissue: 11395.4" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 1 "Nucleoplasm, Cytosol" "HPA051757: , HPA057661: " "unprognostic (3.10e-2)" "unprognostic (4.84e-3)" "unprognostic (2.28e-1)" "unprognostic (3.72e-3)" "unprognostic (2.72e-1)" "unprognostic (3.50e-2)" "unprognostic (3.86e-1)" "unprognostic (1.57e-2)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (4.43e-4)" "unprognostic (7.31e-2)" "unprognostic (3.82e-1)" "unprognostic (1.20e-1)" "unprognostic (9.58e-2)" "unprognostic (2.70e-1)" "unprognostic (4.20e-2)" "unprognostic (1.02e-1)" "unprognostic (1.40e-2)" "unprognostic (4.43e-2)" "unprognostic (1.14e-3)" "unprognostic (2.31e-1)" "unprognostic (3.47e-2)" "potential prognostic favorable (6.35e-5)" "unprognostic (1.30e-1)" "unprognostic (2.13e-2)" "unprognostic (7.67e-2)" "unprognostic (1.48e-1)" ANKRD36C DKFZp667P0924 ENSG00000174501 "Ankyrin repeat domain 36C" Q5JPF3 2 95836919-95991831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.9;salivary gland: 14.6" "Cell type enhanced" "Detected in many" "Foveolar cells: 1110.4;Salivary acinar cells: 1052.2;Sertoli cells: 1194.0" "Cell type enhanced" "Detected in many" "Acinar cells: 1052.2;Gastric glandular cells: 1110.4;Reproductive supporting cells: 1194.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Cell type enriched" "Detected in some" "Microglia and Neuropil: 82824.9" "Not detected" "Not detected" "HPA051757, HPA057661" Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Nucleoplasm, Cytosol" "HPA051757: , HPA057661: " "unprognostic (1.37e-1)" "unprognostic (1.47e-2)" "unprognostic (2.10e-2)" "unprognostic (1.57e-1)" "unprognostic (1.18e-1)" "unprognostic (1.35e-2)" "potential prognostic favorable (5.31e-4)" "unprognostic (4.90e-2)" "unprognostic (3.73e-1)" "unprognostic (5.48e-2)" "unprognostic (2.43e-2)" "unprognostic (1.66e-1)" "unprognostic (3.62e-1)" "unprognostic (5.09e-2)" "unprognostic (5.18e-2)" "unprognostic (8.47e-3)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (2.58e-3)" "unprognostic (3.90e-3)" "unprognostic (1.19e-1)" "unprognostic (2.62e-1)" ANKRD42 "FLJ37874, PPP1R79, SARP" ENSG00000137494 "Ankyrin repeat domain 42" Q8N9B4 11 83193712-83260694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.8" "Cell type enhanced" "Detected in many" "Early spermatids: 164.9;Endometrial ciliated cells: 117.3;Ependymal cells: 95.5;Fallopian tube ciliated cells: 108.2;Late primary spermatocytes: 159.0;Respiratory ciliated cells: 107.3" "Cell type enhanced" "Detected in all" "Ciliated cells: 117.3;Spermatogenic cell types: 164.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 87358 "Fallopian tube cells: 8735764.0" "Tissue enriched" "Detected in single" 57488 "fallopian tube: 5748787.1" HPA039917 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039917: " "unprognostic (1.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "unprognostic (2.12e-1)" "unprognostic (2.48e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (2.69e-1)" "unprognostic (1.29e-3)" "potential prognostic favorable (2.64e-4)" "unprognostic (4.88e-2)" "unprognostic (2.79e-3)" "unprognostic (6.40e-2)" "unprognostic (2.29e-3)" "unprognostic (1.76e-1)" "unprognostic (1.37e-3)" "unprognostic (5.21e-2)" "unprognostic (1.57e-1)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (1.53e-1)" "unprognostic (5.25e-2)" "unprognostic (1.52e-2)" "unprognostic (1.66e-2)" "unprognostic (9.39e-2)" "unprognostic (1.34e-2)" "unprognostic (6.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.26e-1)" "unprognostic (4.38e-2)" ANKRD54 LIAR ENSG00000100124 "Ankyrin repeat domain 54" Q6NXT1 22 37830855-37849327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 75.3;Epididymal efferent duct ciliated cells: 95.7;Fallopian tube ciliated cells: 77.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 95.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 136019 "lung: 10671292.4;lymphoid tissue: 9841639.2;ovary: 20292823.9" HPA071287 Approved Approved Nucleoplasm,Microtubules,Midbody Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 107: Ciliated cells - Cilia assembly & function" 23 "Microtubules, Midbody" Nucleoplasm "HPA071287: " "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (9.37e-3)" "unprognostic (1.69e-1)" "unprognostic (2.19e-3)" "unprognostic (5.26e-2)" "unprognostic (1.19e-2)" "unprognostic (1.35e-1)" "unprognostic (4.15e-2)" "unprognostic (3.76e-2)" "unprognostic (3.35e-1)" "unprognostic (9.98e-3)" "unprognostic (7.29e-3)" "unprognostic (9.38e-3)" "unprognostic (7.63e-2)" "unprognostic (1.50e-1)" "unprognostic (2.48e-1)" "unprognostic (7.23e-2)" "unprognostic (7.36e-2)" "unprognostic (4.20e-2)" "unprognostic (3.26e-2)" "unprognostic (3.28e-2)" "unprognostic (1.18e-2)" "unprognostic (4.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.27e-1)" "unprognostic (2.97e-1)" "unprognostic (2.17e-1)" "unprognostic (1.56e-2)" "unprognostic (2.57e-2)" "unprognostic (1.15e-1)" ANKRD61 ENSG00000157999 "Ankyrin repeat domain 61" A6NGH8 7 6031376-6036552 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "bone marrow: 5.7;testis: 5.6" "Group enriched" "Detected in some" 4 "Early spermatids: 65.7;Late primary spermatocytes: 41.9;Late spermatids: 34.2" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 65.7" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029511, HPA050732" Uncertain Enhanced Nucleoplasm NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoplasm "HPA029511: , HPA050732: " "unprognostic (4.30e-2)" "unprognostic (2.98e-2)" "unprognostic (1.65e-2)" "unprognostic (2.30e-1)" "unprognostic (3.65e-1)" ANKRD65 ENSG00000235098 "Ankyrin repeat domain 65" E5RJM6 1 1418420-1421769 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 83.5;Fallopian secretory cells: 43.4;Fallopian tube ciliated cells: 135.0;Prostatic hillock cells: 45.3;Respiratory ciliated cells: 60.2;Smooth muscle cells: 41.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 135.0;Secretory gland support: 83.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 89.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "myeloid DC: 3.5;plasmacytoid DC: 7.9" "Lineage enriched" "Detected in single" 23 "dendritic cells: 7.9" "Cancer enhanced" "Detected in many" "Bladder cancer: 21.1;head and neck cancer: 18.1" "Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Fallopian tube cells: 12028777.1" "Tissue enriched" "Detected in single" 11646 "fallopian tube: 1164571.7" HPA065720 Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" "Nucleoplasm, Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Primary cilium tip" "HPA065720: " "unprognostic (3.48e-2)" "unprognostic (4.88e-2)" "unprognostic (4.82e-2)" "unprognostic (2.99e-2)" "unprognostic (3.66e-1)" "unprognostic (2.20e-1)" "unprognostic (3.55e-2)" "unprognostic (1.52e-2)" "potential prognostic favorable (3.05e-4)" "unprognostic (2.43e-2)" "unprognostic (5.48e-3)" "unprognostic (2.57e-2)" "unprognostic (1.85e-1)" "potential prognostic favorable (1.52e-5)" "unprognostic (1.90e-1)" "unprognostic (8.68e-2)" "unprognostic (1.96e-1)" "unprognostic (4.24e-2)" "unprognostic (1.55e-1)" "unprognostic (1.22e-1)" "unprognostic (8.13e-2)" "unprognostic (4.30e-2)" "unprognostic (2.63e-3)" "unprognostic (6.13e-2)" "unprognostic (1.91e-2)" "unprognostic (1.73e-2)" "unprognostic (2.49e-2)" "unprognostic (1.70e-1)" "unprognostic (9.57e-2)" ANKRD7 TSA806 ENSG00000106013 "Ankyrin repeat domain 7" Q92527 7 118214669-118496171 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 426 "testis: 803.6" "Group enriched" "Detected in many" 4 "Early spermatids: 2845.4;Late primary spermatocytes: 7264.6" "Cell type enriched" "Detected in many" 41 "Spermatogenic cell types: 7264.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043489, HPA052941" Enhanced Nucleoplasm NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoplasm "HPA043489: , HPA052941: " "unprognostic (5.43e-3)" "unprognostic (1.07e-3)" "unprognostic (8.20e-2)" "unprognostic (6.51e-2)" "unprognostic (9.29e-2)" ANKS3 "FLJ32345, FLJ32767, KIAA1977" ENSG00000168096 "Ankyrin repeat and sterile alpha motif domain containing 3" Q6ZW76 16 4696510-4734378 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 726019.4;Distal tubules: 502083.2" "Tissue enriched" "Detected in single" 5718 "Stomach: 571787.1" "HPA041409, HPA041482" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 9 Nucleoplasm Cytosol "HPA041409: , HPA041482: " "unprognostic (3.77e-2)" "unprognostic (3.89e-3)" "unprognostic (1.96e-1)" "unprognostic (1.31e-2)" "unprognostic (3.56e-2)" "unprognostic (1.36e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (8.63e-4)" "unprognostic (1.34e-3)" "unprognostic (2.18e-1)" "unprognostic (1.85e-2)" "unprognostic (1.27e-1)" "unprognostic (6.00e-2)" "potential prognostic unfavorable (4.45e-5)" "unprognostic (5.16e-2)" "unprognostic (2.74e-1)" "unprognostic (4.44e-1)" "unprognostic (2.76e-2)" "unprognostic (1.36e-1)" "unprognostic (2.12e-2)" "unprognostic (3.33e-2)" "unprognostic (3.80e-1)" "unprognostic (2.79e-2)" "unprognostic (3.02e-2)" "unprognostic (1.09e-1)" "unprognostic (8.03e-2)" "unprognostic (1.39e-1)" "unprognostic (2.70e-1)" "unprognostic (1.54e-1)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" ANLN "ANILLIN, scra, Scraps" ENSG00000011426 "Anillin, actin binding protein" Q9NQW6 7 36389821-36453791 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 163.3" "Cell type enhanced" "Detected in many" "Early spermatids: 185.0;Erythrocyte progenitors: 91.7;Gastric progenitor cells: 74.3;Late primary spermatocytes: 95.5;Monocyte progenitors: 259.4;Neutrophil progenitors: 134.9;Oligodendrocytes: 484.2" "Cell type enhanced" "Detected in many" "Glial cells: 484.2;Mononuclear phagocytes: 259.4;Neutrophils: 134.9;Spermatogenic cell types: 185.0" "Cell type enriched" "Detected in all" 6 "oligodendrocyte: 798.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 71651868.6;Microglia and Neuropil: 23522805.1" "Group enriched" "Detected in some" "cerebral cortex: 24593177.7;lung: 7809659.2" "HPA005680, CAB033902, HPA050556, CAB062547, CAB068175" Enhanced Supported Nucleoplasm,Midbody Yes Yes "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 571 Nucleoplasm Midbody "CAB033902: , CAB062547: , CAB068175: , HPA005680: , HPA050556: " "unprognostic (1.17e-2)" "unprognostic (1.82e-2)" "unprognostic (2.26e-1)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (1.98e-1)" "unprognostic (1.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (6.88e-4)" "validated prognostic unfavorable (1.38e-4)" "validated prognostic unfavorable (2.73e-6)" "potential prognostic unfavorable (2.05e-10)" "validated prognostic unfavorable (6.50e-6)" "validated prognostic unfavorable (8.72e-10)" "validated prognostic unfavorable (4.21e-7)" "validated prognostic unfavorable (1.34e-4)" "unprognostic (1.34e-1)" "unprognostic (8.27e-2)" "unprognostic (3.07e-1)" "unprognostic (2.48e-1)" "validated prognostic unfavorable (5.53e-6)" "validated prognostic unfavorable (1.76e-5)" "unprognostic (2.05e-2)" "unprognostic (2.00e-1)" "unprognostic (1.98e-2)" "unprognostic (3.06e-2)" "unprognostic (1.40e-2)" "unprognostic (2.71e-1)" "unprognostic (6.10e-2)" "unprognostic (4.69e-2)" ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 715.2;Neutrophils: 371.8" "Cell type enhanced" "Detected in all" "Neutrophils: 715.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Large ducts: 5633948.8;Neutrophils: 16994942.3" "Tissue enhanced" "Detected in many" "intestine: 3920353.0" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 1 "Plasma membrane" "Vesicles, Primary cilium" "HPA016624: , HPA051569: " "unprognostic (2.10e-3)" "unprognostic (2.67e-3)" "unprognostic (1.23e-1)" "unprognostic (1.83e-2)" "unprognostic (5.86e-3)" "unprognostic (2.63e-1)" "unprognostic (1.00e-1)" "unprognostic (3.09e-1)" "unprognostic (1.56e-1)" "unprognostic (5.56e-2)" "unprognostic (4.39e-3)" "unprognostic (5.60e-2)" "potential prognostic favorable (1.31e-4)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (2.63e-1)" "unprognostic (2.51e-2)" "unprognostic (1.62e-2)" "unprognostic (7.20e-2)" "unprognostic (1.61e-1)" "unprognostic (6.24e-2)" "unprognostic (1.69e-2)" "unprognostic (8.38e-2)" "unprognostic (1.03e-1)" "unprognostic (2.13e-1)" "unprognostic (2.65e-1)" "unprognostic (1.60e-1)" "unprognostic (2.33e-2)" "unprognostic (4.87e-2)" "unprognostic (2.38e-1)" "unprognostic (1.26e-2)" "unprognostic (1.97e-2)" ANO3 "C11orf25, DYT23, GENX-3947, TMEM16C" ENSG00000134343 "Anoctamin 3" Q9BYT9 11 26188842-26663289 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 20 "brain: 58.4;epididymis: 54.2" "Cell type enhanced" "Detected in many" "Adipocytes: 199.1;Brain excitatory neurons: 165.4;Brain inhibitory neurons: 405.4;Cone photoreceptor cells: 70.4;Epididymal principal cells: 202.3;Gonadotrophs: 61.3;Hepatic stellate cells: 284.0;Oligodendrocyte progenitor cells: 65.3;Pericytes: 96.4" "Cell type enhanced" "Detected in many" "Adipocytes: 199.1;Neuronal cells: 405.4;Reproductive supporting cells: 202.3;Stellate cells: 284.0" "Cell type enhanced" "Detected in many" "medium spiny neuron: 1104.8" "Cancer enhanced" "Detected in single" "Kidney Renal Clear Cell Carcinoma (TCGA): 1.2" "Region enriched" "Detected in all" 5 "basal ganglia: 129.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Rhabdoid: 8.3" "Testis - Early spermatids" "Region enhanced" "Detected in all" "basal ganglia: 158.9" "Region enriched" "Detected in all" 7 "basal ganglia: 211.0" "Group enriched" "Detected in some" 409 "Astrocytes and Neuropil: 49490.7;Microglia and Neuropil: 37014.7;T-cells: 36139.8" "Tissue enriched" "Detected in single" 1549 "cerebral cortex: 154900.0" "HPA041629, CAB080586" Uncertain Supported "Microtubules,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 22: Epididymis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Microtubules, Primary cilium, Cytosol" "Mitotic spindle, Basal body" "CAB080586: , HPA041629: " "unprognostic (3.04e-2)" "validated prognostic favorable (9.03e-8)" "validated prognostic favorable (4.02e-6)" ANO9 "PIG5, TMEM16J, TP53I5" ENSG00000185101 "Anoctamin 9" A1A5B4 11 417933-442011 "Predicted membrane proteins, Transporters" "Lipid metabolism, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 32.2;skin 1: 26.3" "Cell type enhanced" "Detected in many" "Colonocytes: 82.2;Enteric stem cells: 49.2;Enteric transient amplifying cells: 52.5;Enterocytes: 109.8;Epididymal principal cells: 34.6;Goblet cells: 77.1;Paneth cells: 65.7;Proximal tubule cells: 34.2" "Cell type enhanced" "Detected in many" "Enterocytes: 109.8;Goblet cells: 77.1;Secretory gland support: 65.7" "Cell type enriched" "Detected in single" 19 "leukocyte: 19.2" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 26.2;Rectum Adenocarcinoma (TCGA): 25.4" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 48 "B-cells: 2.1;NK-cells: 4.1;T-cells: 8.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 16.4" "Adipose subcutaneous - T-cells, Adrenal gland - T-cells, Liver - T-cells, Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "B-cells: 1703952.3;Keratinocytes: 1546663.2;Macrophages: 3301771.3;T-cells: 1797990.8" "Group enriched" "Detected in some" 34038 "intestine: 4060736.9;lymphoid tissue: 2746773.4" "HPA039948, HPA040112" Approved Uncertain "Golgi apparatus" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 2 "Golgi apparatus" "HPA039948: , HPA040112: " "unprognostic (1.31e-3)" "unprognostic (3.25e-1)" "unprognostic (7.83e-2)" "unprognostic (5.61e-2)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (1.42e-1)" "unprognostic (3.71e-1)" "potential prognostic favorable (1.64e-4)" "unprognostic (2.75e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (2.76e-2)" "unprognostic (3.35e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (1.41e-3)" "unprognostic (1.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.16e-3)" "unprognostic (1.18e-1)" "unprognostic (2.46e-3)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (1.55e-2)" "unprognostic (9.72e-2)" "unprognostic (3.21e-2)" "unprognostic (1.85e-2)" ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7699.2" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 89658.7" "Cell type enriched" "Detected in all" 4 "Apical squamous epithelial cells: 89658.7" "Group enriched" "Detected in many" 13 "endothelial cell: 140.6;ependymal cell: 259.6;fibroblast: 148.8;leukocyte: 226.5;vascular associated smooth muscle cell: 74.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2824.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Neutrophils: 2186165616.1" "Low tissue specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693, CAB080415" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA Yes 17600000 24000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 35 "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: , CAB035987: , CAB058693: , CAB080415: , HPA011271: , HPA011272: " "unprognostic (2.41e-3)" "unprognostic (9.20e-3)" "unprognostic (1.75e-1)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (6.39e-2)" "unprognostic (2.17e-2)" "unprognostic (5.11e-3)" "unprognostic (8.49e-2)" "unprognostic (4.02e-2)" "unprognostic (2.83e-2)" "unprognostic (2.00e-1)" "unprognostic (2.07e-1)" "unprognostic (2.02e-2)" "unprognostic (1.28e-1)" "unprognostic (1.11e-2)" "unprognostic (3.05e-2)" "unprognostic (1.69e-1)" "unprognostic (1.17e-1)" "unprognostic (4.63e-2)" "unprognostic (1.64e-1)" "unprognostic (1.86e-3)" "unprognostic (3.66e-3)" "unprognostic (3.30e-1)" "unprognostic (1.30e-1)" "unprognostic (4.76e-3)" "unprognostic (1.51e-1)" "unprognostic (3.59e-2)" "unprognostic (4.87e-2)" "potential prognostic favorable (8.16e-4)" "unprognostic (2.84e-2)" ANXA2R "AXIIR, C5orf39" ENSG00000177721 "Annexin A2 receptor" Q3ZCQ2 5 43039233-43043170 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.7;lymphoid tissue: 24.4" "Cell type enhanced" "Detected in some" "NK-cells: 1.0;Podocytes: 1.3;T-cells: 1.1" "Cell type enhanced" "Detected in some" "NK-cells: 1.0;Renal nephron cells: 1.3;T-cells: 1.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "gdT-cell: 54.1;MAIT T-cell: 63.6;memory B-cell: 34.5;memory CD4 T-cell: 56.3;memory CD8 T-cell: 59.9;naive B-cell: 33.0;naive CD4 T-cell: 96.6;naive CD8 T-cell: 72.3;NK-cell: 24.9;T-reg: 66.7" "Group enriched" "Detected in all" 6 "B-cells: 34.5;NK-cells: 24.9;T-cells: 96.6" "Cancer enriched" "Detected in many" 4 "Leukemia: 25.9" "Colon - Endothelial cells, Liver - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA051482 Uncertain Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 105: Non-specific - Mixed function" 1 Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA051482: " "unprognostic (1.44e-1)" "unprognostic (8.66e-3)" "unprognostic (1.57e-1)" "unprognostic (6.91e-2)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (6.94e-3)" "unprognostic (1.77e-2)" "unprognostic (7.21e-3)" "unprognostic (5.25e-2)" "unprognostic (3.12e-2)" "unprognostic (1.48e-1)" "unprognostic (2.01e-2)" "unprognostic (5.74e-3)" "unprognostic (6.18e-2)" "unprognostic (4.32e-2)" "unprognostic (2.81e-1)" "unprognostic (7.35e-2)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.66e-2)" "unprognostic (6.19e-3)" "unprognostic (3.84e-1)" "unprognostic (7.74e-2)" "unprognostic (3.38e-2)" "unprognostic (9.21e-2)" "unprognostic (2.11e-1)" "unprognostic (4.75e-2)" "unprognostic (9.80e-2)" "unprognostic (2.13e-2)" ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 319.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 816.7;Breast myoepithelial cells: 341.9;Esophageal apical cells: 750.9;Megakaryocytes: 463.6;Migrating cytotrophoblasts: 329.8;Neutrophil progenitors: 1295.8;Neutrophils: 784.3;Pancreatic duct cells: 370.7;Salivary duct cells: 301.8" "Cell type enhanced" "Detected in many" "Alveolar cells: 816.7;Apical squamous epithelial cells: 750.9;Neutrophils: 1295.8" "Cell type enriched" "Detected in many" 5 "endothelial cell: 341.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 328 "neutrophil: 208.7" "Lineage enriched" "Detected in single" 328 "granulocytes: 208.7" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neutrophils: 1463854758.3" "Low tissue specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 5000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" "Plasma membrane" "HPA013398: , HPA013431: " "unprognostic (3.22e-1)" "unprognostic (4.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.71e-2)" "unprognostic (2.26e-3)" "unprognostic (1.44e-1)" "unprognostic (3.50e-1)" "unprognostic (7.04e-3)" "unprognostic (4.83e-3)" "unprognostic (7.43e-2)" "unprognostic (1.32e-3)" "unprognostic (2.68e-2)" "unprognostic (8.09e-2)" "unprognostic (1.59e-2)" "unprognostic (1.01e-3)" "unprognostic (2.32e-1)" "unprognostic (4.47e-1)" "unprognostic (3.11e-2)" "unprognostic (2.14e-3)" "unprognostic (5.09e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (4.35e-2)" "unprognostic (2.65e-1)" "unprognostic (7.54e-3)" "unprognostic (5.99e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-1)" "unprognostic (2.24e-1)" "unprognostic (6.40e-2)" "unprognostic (2.71e-2)" ANXA5 "ANX5, CPB-I, ENX2, PAP-I, RPRGL3, VAC-alph" ENSG00000164111 "Annexin A5" P08758 4 121667946-121696995 "Disease related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Blood coagulation, Hemostasis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1348.3;Extravillous trophoblasts: 1407.8;Migrating cytotrophoblasts: 1188.4;monocytes: 891.1;Pancreatic duct cells: 1031.2;Syncytiotrophoblasts: 1283.6" "Cell type enhanced" "Detected in all" "Trophoblast cells: 1407.8" "Cell type enhanced" "Detected in many" "fibroblast: 163.7;pericyte: 160.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islets: 1348640721.2" "Low tissue specificity" "Detected in all" "CAB003677, HPA035330" Approved Approved "Nuclear membrane" NA NA 5400000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 21: Non-specific - Metabolism" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 19 "Nuclear membrane" "CAB003677: , HPA035330: " "unprognostic (2.14e-1)" "unprognostic (1.58e-1)" "unprognostic (5.57e-2)" "unprognostic (3.12e-2)" "unprognostic (1.76e-1)" "unprognostic (2.99e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (1.91e-5)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (1.91e-3)" "potential prognostic favorable (6.92e-4)" "unprognostic (1.58e-1)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (8.95e-2)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (6.23e-4)" "potential prognostic unfavorable (7.48e-4)" "unprognostic (1.10e-2)" "unprognostic (2.97e-1)" "unprognostic (6.88e-2)" "unprognostic (9.71e-3)" "unprognostic (1.55e-1)" "unprognostic (9.47e-2)" "unprognostic (1.09e-1)" "unprognostic (4.07e-2)" "unprognostic (1.67e-1)" "unprognostic (1.56e-3)" "unprognostic (1.29e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" ANXA6 ANX6 ENSG00000197043 "Annexin A6" P08133 5 151100706-151157815 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.1;Hepatic stellate cells: 309.8;Peritubular myoid cells: 216.4;Rod photoreceptor cells: 275.8;Syncytiotrophoblasts: 277.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA002462, CAB005077, HPA009650, HPA009977" Enhanced Approved "Basal body,Cytosol" NA NA 1600000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 Cytosol "Basal body" "CAB005077: , HPA002462: , HPA009650: , HPA009977: " "unprognostic (1.27e-1)" "unprognostic (3.35e-1)" "unprognostic (1.84e-2)" "unprognostic (6.13e-2)" "unprognostic (6.87e-2)" "unprognostic (5.30e-2)" "unprognostic (1.78e-1)" "unprognostic (1.10e-1)" "unprognostic (4.78e-2)" "unprognostic (1.46e-1)" "unprognostic (1.69e-2)" "unprognostic (2.61e-1)" "unprognostic (4.98e-3)" "unprognostic (1.42e-1)" "unprognostic (7.79e-3)" "unprognostic (5.10e-2)" "unprognostic (1.55e-1)" "unprognostic (1.04e-2)" "unprognostic (2.22e-1)" "unprognostic (3.70e-3)" "unprognostic (1.99e-2)" "potential prognostic favorable (8.80e-4)" "unprognostic (8.95e-2)" "unprognostic (3.09e-2)" "unprognostic (8.52e-2)" "unprognostic (2.04e-2)" "unprognostic (2.48e-1)" "unprognostic (6.69e-2)" "unprognostic (3.40e-1)" "unprognostic (1.59e-3)" "unprognostic (2.58e-2)" AP1G1 "ADTG, CLAPG1" ENSG00000166747 "Adaptor related protein complex 1 subunit gamma 1" O43747 16 71729000-71809201 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 726.5" "Cell type enhanced" "Detected in all" "Neutrophils: 726.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB009049, HPA041224, HPA070312" Approved Enhanced "Golgi apparatus,Vesicles,Cytosol" NA NA 130000 "Cluster 28: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 "Golgi apparatus, Vesicles" Cytosol "CAB009049: , HPA041224: , HPA070312: " "unprognostic (4.28e-1)" "unprognostic (8.46e-2)" "unprognostic (2.25e-1)" "unprognostic (3.67e-2)" "unprognostic (1.20e-1)" "unprognostic (1.23e-2)" "unprognostic (1.69e-1)" "unprognostic (8.89e-2)" "unprognostic (3.30e-1)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.32e-8)" "unprognostic (1.20e-2)" "unprognostic (3.54e-3)" "unprognostic (3.19e-2)" "unprognostic (1.11e-1)" "unprognostic (2.43e-1)" "unprognostic (2.08e-2)" "unprognostic (1.65e-3)" "unprognostic (3.81e-2)" "unprognostic (5.62e-2)" "unprognostic (5.03e-2)" "unprognostic (3.01e-3)" "potential prognostic unfavorable (4.16e-5)" "unprognostic (5.39e-2)" "unprognostic (5.12e-3)" "unprognostic (1.76e-1)" "unprognostic (5.00e-2)" "unprognostic (2.78e-1)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (3.84e-1)" AP3D1 ADTD ENSG00000065000 "Adaptor related protein complex 3 subunit delta 1" O14617 19 2100988-2164468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Albinism, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 44388595.0" HPA074408 Approved Cytosol No No 19000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 19 Cytosol "HPA074408: " "unprognostic (7.39e-2)" "unprognostic (6.02e-3)" "unprognostic (2.48e-2)" "unprognostic (1.03e-1)" "unprognostic (1.62e-2)" "unprognostic (1.59e-1)" "unprognostic (2.90e-1)" "unprognostic (2.49e-1)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (1.78e-4)" "potential prognostic favorable (8.34e-5)" "unprognostic (2.90e-1)" "unprognostic (8.11e-3)" "potential prognostic unfavorable (5.45e-4)" "unprognostic (4.89e-3)" "unprognostic (1.83e-1)" "unprognostic (2.92e-3)" "unprognostic (5.04e-2)" "unprognostic (2.50e-1)" "unprognostic (5.38e-2)" "unprognostic (5.78e-2)" "unprognostic (1.42e-2)" "unprognostic (8.71e-2)" "unprognostic (1.03e-1)" "unprognostic (2.59e-1)" "unprognostic (3.06e-3)" "unprognostic (3.84e-2)" "unprognostic (4.20e-2)" "unprognostic (2.80e-2)" "unprognostic (8.44e-2)" "unprognostic (1.90e-3)" AP4B1 "BETA-4, SPG47" ENSG00000134262 "Adaptor related protein complex 4 subunit beta 1" Q9Y6B7 1 113894194-113905201 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Esophageal apical cells: 39.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1207229.8" "Tissue enriched" "Detected in some" "bone marrow: 427437.0" "HPA028162, HPA028652" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 84: Apical squamous epithelium - Cornification" 16 Vesicles "HPA028162: , HPA028652: " "unprognostic (3.13e-1)" "unprognostic (2.31e-1)" "unprognostic (8.12e-2)" "unprognostic (1.01e-1)" "unprognostic (1.93e-1)" "unprognostic (6.20e-2)" "unprognostic (1.42e-1)" "unprognostic (9.83e-3)" "unprognostic (3.15e-1)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (9.11e-2)" "potential prognostic unfavorable (1.14e-7)" "unprognostic (1.80e-1)" "unprognostic (7.75e-2)" "unprognostic (2.09e-2)" "unprognostic (2.36e-1)" "unprognostic (7.22e-2)" "unprognostic (4.53e-2)" "unprognostic (2.76e-1)" "unprognostic (1.36e-1)" "unprognostic (3.51e-1)" "unprognostic (1.61e-1)" "unprognostic (6.29e-3)" "unprognostic (2.66e-1)" "unprognostic (5.10e-1)" "unprognostic (1.72e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-1)" "unprognostic (6.22e-2)" AP5B1 "AP-5, DKFZp761E198, PP1030" ENSG00000254470 "Adaptor related protein complex 5 subunit beta 1" Q2VPB7 11 65773898-65780976 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 41.5" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 57.7;Neutrophil progenitors: 82.5;Neutrophils: 188.6;Syncytiotrophoblasts: 49.1;Urothelial cells: 50.0" "Cell type enhanced" "Detected in many" "Neutrophils: 188.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "neutrophil: 25.0" "Lineage enriched" "Detected in many" 14 "granulocytes: 25.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 2121672.1" "Group enriched" "Detected in many" "bone marrow: 419275.1;intestine: 741953.8;lymphoid tissue: 309582.7" "HPA065739, HPA067880" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 11 "Nucleoplasm, Vesicles" "Golgi apparatus" "HPA065739: , HPA067880: " "unprognostic (3.47e-3)" "unprognostic (1.33e-1)" "unprognostic (6.74e-2)" "unprognostic (2.05e-1)" "unprognostic (2.60e-1)" "unprognostic (1.32e-2)" "unprognostic (2.19e-1)" "unprognostic (2.52e-2)" "unprognostic (9.89e-2)" "potential prognostic favorable (9.95e-6)" "unprognostic (2.40e-1)" "unprognostic (1.22e-2)" "unprognostic (5.53e-3)" "unprognostic (1.35e-3)" "unprognostic (5.97e-2)" "unprognostic (1.33e-1)" "unprognostic (8.39e-3)" "unprognostic (7.49e-3)" "unprognostic (2.87e-2)" "unprognostic (1.85e-1)" "unprognostic (3.77e-2)" "unprognostic (1.64e-1)" "unprognostic (4.33e-2)" "unprognostic (1.38e-1)" "unprognostic (5.06e-1)" "unprognostic (8.26e-2)" "unprognostic (2.62e-2)" "unprognostic (3.68e-2)" "unprognostic (2.13e-1)" AP5S1 "C20orf29, FLJ11168" ENSG00000125843 "Adaptor related protein complex 5 subunit sigma 1" Q9NUS5 20 3820524-3828838 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 28.7;Platelets: 53.6" "Cell type enhanced" "Detected in many" "Platelets: 53.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 1134776.0" "Tissue enriched" "Detected in some" "intestine: 3986268.7" "CAB034200, HPA043533, HPA048244" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 33: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 10 "Nucleoplasm, Cytosol" "CAB034200: , HPA043533: , HPA048244: " "unprognostic (1.22e-2)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (4.64e-2)" "unprognostic (2.99e-2)" "unprognostic (1.50e-1)" "unprognostic (2.54e-2)" "unprognostic (3.27e-2)" "unprognostic (1.73e-1)" "unprognostic (4.06e-2)" "unprognostic (1.84e-3)" "unprognostic (7.96e-2)" "potential prognostic favorable (6.87e-4)" "unprognostic (1.13e-2)" "unprognostic (1.95e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (1.76e-5)" "unprognostic (3.21e-1)" "unprognostic (9.60e-3)" "unprognostic (2.38e-1)" "unprognostic (1.52e-2)" "unprognostic (1.11e-1)" "unprognostic (2.97e-2)" "unprognostic (1.08e-1)" "unprognostic (4.58e-2)" "unprognostic (3.55e-1)" "unprognostic (4.31e-1)" "unprognostic (2.57e-1)" "unprognostic (3.52e-2)" "unprognostic (8.72e-2)" APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "Adipocytes: 600.2;Kupffer cells: 435.6;Macrophages: 333.6;Microglia: 2215.0;Monocyte progenitors: 346.9;monocytes: 439.8;Neutrophil progenitors: 864.7;Neutrophils: 2909.8;NK-cells: 353.3;pDCs: 368.0;T-cells: 420.4" "Group enriched" "Detected in many" 4 "Glial cells: 2215.0;Neutrophils: 2909.8" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 2560.2" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 42.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 183.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Kidney cancer: 43.1;Leukemia: 69.3;lymphoma: 96.1;Myeloma: 25.7" "Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Testis - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 13514019.6;Macrophages: 11903308.8;Neutrophils: 5855351.0;T-cells: 18890585.7" "Group enriched" "Detected in many" "bone marrow: 11589871.7;intestine: 5642369.1;lymphoid tissue: 17890364.0;ovary: 4571960.0" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "Plasma membrane, Cytosol" "HPA017009: , HPA063903: " "unprognostic (3.10e-1)" "unprognostic (2.32e-2)" "unprognostic (1.06e-1)" "unprognostic (6.05e-2)" "unprognostic (5.30e-2)" "unprognostic (2.66e-1)" "unprognostic (2.73e-1)" "unprognostic (2.02e-1)" "unprognostic (2.92e-2)" "unprognostic (1.47e-1)" "potential prognostic favorable (1.72e-4)" "unprognostic (2.75e-1)" "potential prognostic favorable (9.92e-6)" "unprognostic (1.16e-2)" "unprognostic (1.46e-3)" "unprognostic (5.95e-2)" "unprognostic (3.45e-2)" "unprognostic (6.95e-2)" "unprognostic (3.60e-1)" "unprognostic (2.55e-1)" "unprognostic (5.32e-1)" "unprognostic (3.27e-2)" "unprognostic (6.56e-2)" "unprognostic (1.17e-1)" "unprognostic (2.96e-2)" "unprognostic (2.47e-1)" "unprognostic (7.70e-3)" "unprognostic (7.37e-3)" "unprognostic (7.36e-3)" "unprognostic (1.97e-1)" "unprognostic (2.40e-1)" APBB2 "FE65L, FE65L1, MGC35575" ENSG00000163697 "Amyloid beta precursor protein binding family B member 2" Q92870 4 40810027-41216714 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 752.3;Alveolar cells type 1: 926.5;Distal convoluted tubule cells: 1637.7;Oligodendrocyte progenitor cells: 971.6;Oligodendrocytes: 1046.9;Podocytes: 1784.0" "Cell type enhanced" "Detected in many" "Renal nephron cells: 1784.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 16 "naive B-cell: 5.5" "Lineage enriched" "Detected in single" 24 "B-cells: 5.5" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 1848513.9;Pancreatic islets: 611835.1;Smooth muscle cells: 2212187.3" "Group enriched" "Detected in many" "cerebral cortex: 336465.5;fallopian tube: 436252.7;lymphoid tissue: 669364.0" HPA023542 Approved Approved Mitochondria No No "Cluster 34: B-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 57: Podocytes - Glomerular filtration" 10 Mitochondria "HPA023542: " "unprognostic (1.42e-1)" "unprognostic (2.24e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (1.92e-6)" "unprognostic (1.81e-1)" "unprognostic (1.01e-1)" "unprognostic (6.78e-2)" "unprognostic (1.43e-2)" "unprognostic (1.26e-1)" "unprognostic (2.37e-2)" "potential prognostic favorable (1.12e-4)" "unprognostic (2.32e-3)" "unprognostic (2.29e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (1.39e-4)" "unprognostic (9.99e-2)" "unprognostic (3.15e-2)" "unprognostic (1.17e-2)" "unprognostic (1.14e-1)" "validated prognostic unfavorable (4.46e-4)" "validated prognostic unfavorable (5.87e-5)" "unprognostic (7.16e-2)" "unprognostic (2.23e-3)" "unprognostic (1.31e-1)" "unprognostic (9.02e-3)" "unprognostic (1.01e-1)" "unprognostic (2.57e-1)" "unprognostic (2.73e-2)" "unprognostic (1.88e-1)" "unprognostic (1.31e-3)" "unprognostic (2.49e-2)" APC2 APCL ENSG00000115266 "APC regulator of WNT signaling pathway 2" O95996 19 1446302-1473244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Disease variant, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 48.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 85.1;Astrocytes: 176.9;Bergmann glia: 105.1;Brain excitatory neurons: 44.0;Brain inhibitory neurons: 47.8;Ependymal cells: 47.5;Müller glia: 57.7;Oligodendrocyte progenitor cells: 58.4;Oligodendrocytes: 40.9;Other brain neurons: 40.1;Retinal amacrine cells: 94.8;Retinal bipolar cells: 52.6;Retinal horizontal cells: 46.1" "Group enriched" "Detected in many" 4 "Adrenal endocrine cells: 85.1;Ciliated cells: 47.5;Glial cells: 176.9;Neuronal cells: 94.8" "Cell type enhanced" "Detected in all" "astrocyte: 210.8" "Cancer enriched" "Detected in some" 28 "Glioblastoma Multiforme (TCGA): 37.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Neuroblastoma: 34.0;Rhabdoid: 10.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Astrocytes and Neuropil: 7093686.9" "Tissue enriched" "Detected in some" "salivary gland: 5856880.0" HPA078002 Supported "Cytokinetic bridge,Midbody,Primary cilium,Cytosol" Yes No "Cluster 10: Brain - Synaptic signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 6 "Cytokinetic bridge" "Midbody, Primary cilium, Cytosol" "HPA078002: " "unprognostic (4.72e-1)" "unprognostic (1.14e-1)" "unprognostic (1.22e-2)" APCDD1L FLJ90166 ENSG00000198768 "APC down-regulated 1 like" Q8NCL9 20 58459101-58515399 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "blood vessel: 5.3;salivary gland: 18.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Breast secretory cells: 34.2;Cardiomyocytes: 15.0;Corticotrophs: 44.7;Fibro-adipogenic progenitors: 20.6;Lacrimal acinar cells: 100.5;Pancreatic islet cells: 14.6;Renal collecting duct principal cells: 15.1;Renal connecting tubule cells: 72.5" "Cell type enhanced" "Detected in many" "Acinar cells: 100.5;Ductal cells: 72.5;Pituitary endocrine cells: 44.7;Secretory cells: 34.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 6.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 44.8" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Group enriched" "Detected in some" 2780 "Collecting ducts: 310289.9;Pancreatic islets: 245639.8" "Not detected" "Not detected" HPA067015 Uncertain Uncertain Mitochondria No No "Cluster 82: Salivary gland - Secretion" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 3 Mitochondria "HPA067015: " "unprognostic (8.93e-2)" "unprognostic (1.66e-1)" "unprognostic (2.89e-1)" "unprognostic (1.30e-2)" "potential prognostic unfavorable (9.71e-5)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (5.30e-6)" "unprognostic (7.15e-3)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (2.97e-2)" "validated prognostic unfavorable (6.10e-4)" "validated prognostic unfavorable (8.07e-4)" "unprognostic (2.88e-2)" APEH "D3F15S2, D3S48E, DNF15S2" ENSG00000164062 "Acylaminoacyl-peptide hydrolase" P13798 3 49674014-49683971 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 99.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA029700, HPA029701, HPA029702, HPA029703" Enhanced Enhanced Cytosol No No 7900000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 6 Cytosol "HPA029700: , HPA029701: , HPA029702: , HPA029703: " "unprognostic (5.23e-3)" "unprognostic (2.04e-1)" "unprognostic (9.18e-2)" "unprognostic (5.55e-2)" "unprognostic (4.67e-2)" "unprognostic (7.22e-3)" "unprognostic (3.03e-1)" "unprognostic (8.32e-2)" "unprognostic (9.71e-2)" "potential prognostic unfavorable (6.21e-5)" "potential prognostic favorable (1.44e-6)" "unprognostic (1.44e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.67e-1)" "unprognostic (7.13e-2)" "unprognostic (4.32e-1)" "unprognostic (1.10e-2)" "unprognostic (5.32e-2)" "unprognostic (2.89e-2)" "unprognostic (1.41e-1)" "unprognostic (1.60e-2)" "unprognostic (6.60e-2)" "unprognostic (4.37e-2)" "unprognostic (1.03e-1)" "unprognostic (3.48e-2)" "unprognostic (3.25e-1)" "unprognostic (5.04e-2)" "unprognostic (2.27e-2)" "unprognostic (1.91e-1)" "unprognostic (6.50e-2)" "unprognostic (2.69e-2)" APEX1 "APE, APE-1, APEN, APEX, APX, HAP1, REF-1, REF1" ENSG00000100823 "Apurinic/apyrimidinic endodeoxyribonuclease 1" P27695 14 20455191-20457772 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Activator, DNA-binding, Endonuclease, Exonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA000956, HPA002564, CAB004294, CAB047307" Supported Supported Nucleoplasm,Centrosome Yes No 220000 "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 78 Nucleoplasm Centrosome "CAB004294: , CAB047307: , HPA000956: , HPA002564: " "unprognostic (2.12e-1)" "unprognostic (3.10e-2)" "unprognostic (1.35e-2)" "unprognostic (1.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.79e-1)" "unprognostic (4.56e-2)" "unprognostic (7.15e-2)" "unprognostic (4.33e-3)" "unprognostic (2.10e-3)" "potential prognostic favorable (8.71e-6)" "unprognostic (4.93e-3)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (1.41e-5)" "validated prognostic unfavorable (8.78e-6)" "unprognostic (2.20e-2)" "unprognostic (2.05e-3)" "unprognostic (1.03e-2)" "unprognostic (1.65e-1)" "unprognostic (5.89e-2)" "unprognostic (1.61e-1)" "unprognostic (4.33e-3)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (2.58e-2)" "unprognostic (1.74e-1)" "unprognostic (2.46e-2)" "unprognostic (5.83e-2)" "unprognostic (2.89e-2)" "unprognostic (3.35e-2)" "potential prognostic favorable (4.23e-4)" APOB ENSG00000084674 "Apolipoprotein B" P04114 2 21001429-21044073 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Heparin-binding "Atherosclerosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 143 "intestine: 286.7;liver: 1114.1" "Group enriched" "Detected in some" 7 "Enterocytes: 1716.3;Hepatocytes: 3326.2" "Group enriched" "Detected in many" 7 "Enterocytes: 1716.3;Hepatocytes: 3326.2" "Cell type enriched" "Detected in some" 11 "fibroblast: 14.7" "Cancer enriched" "Detected in some" 80 "Liver Hepatocellular Carcinoma (TCGA): 362.3" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "liver cancer: 178.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in all" "Alveolar cell types: 345778716.5" "Tissue enhanced" "Detected in all" "lung: 933560498.9" "CAB016070, HPA049793, CAB080297, CAB080298, CAB080299" Supported Supported Vesicles,Cytosol "Secreted to blood" Apolipoprotein NA NA 1490000000000 250000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 39 "Vesicles, Cytosol" "CAB016070: , CAB080297: , CAB080298: , CAB080299: , HPA049793: " "unprognostic (1.15e-1)" "unprognostic (9.11e-3)" "unprognostic (6.55e-2)" "unprognostic (1.24e-2)" "unprognostic (1.04e-1)" "unprognostic (3.64e-1)" "unprognostic (2.18e-1)" "unprognostic (1.05e-2)" "unprognostic (2.98e-1)" APOBEC3F "ARP8, BK150C2.4.MRNA, KA6" ENSG00000128394 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3F" Q8IUX4 22 39040604-39055972 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 8.7;leukocyte: 18.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 11549121.3;Granulosa cells: 12185769.1;T-cells: 10254021.3" "Low tissue specificity" "Detected in many" HPA073637 Uncertain Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 26 "Nucleoplasm, Cytosol" "HPA073637: " "unprognostic (1.05e-1)" "unprognostic (1.77e-2)" "unprognostic (4.31e-1)" "unprognostic (7.80e-2)" "unprognostic (1.46e-1)" "unprognostic (4.99e-2)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (4.23e-7)" "unprognostic (1.22e-1)" "unprognostic (2.68e-3)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (5.97e-2)" "unprognostic (6.91e-3)" "unprognostic (2.70e-2)" "unprognostic (1.07e-1)" "unprognostic (7.70e-3)" "unprognostic (1.80e-1)" "unprognostic (4.43e-2)" "unprognostic (4.79e-3)" "unprognostic (8.83e-2)" "unprognostic (3.65e-1)" "unprognostic (4.88e-2)" "unprognostic (5.93e-3)" "unprognostic (1.84e-1)" "unprognostic (1.87e-1)" "unprognostic (8.08e-2)" "unprognostic (5.87e-2)" "unprognostic (7.79e-2)" "unprognostic (4.62e-2)" "unprognostic (4.36e-2)" "unprognostic (1.35e-1)" APOBEC3G "bK150C2.7, CEM15, dJ494G10.1, FLJ12740, MDS019" ENSG00000239713 "Apolipoprotein B mRNA editing enzyme catalytic subunit 3G" Q9HC16 22 39077067-39087743 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 43.0" "Cell type enhanced" "Detected in many" "B-cells: 40.0;Early spermatids: 49.6;Hofbauer cells: 39.8;Innate lymphoid cells: 45.7;Megakaryocytes: 43.3;NK-cells: 166.4;Plasma cells: 81.9;Sertoli cells: 60.8;T-cells: 103.7" "Cell type enhanced" "Detected in many" "NK-cells: 166.4;Plasma cells: 81.9;T-cells: 103.7" "Cell type enriched" "Detected in some" 4 "leukocyte: 72.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bile duct cancer: 57.4" "Breast - T-cells, Lung - T-cells, Testis - Sertoli cells, Thyroid gland - T-cells" "Cell type enhanced" "Detected in many" "T-cells: 6754450.0" "Tissue enriched" "Detected in some" "lymphoid tissue: 7678384.9" "HPA001812, HPA073637" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "Nucleoplasm, Cytosol" "HPA001812: , HPA073637: " "unprognostic (1.82e-1)" "potential prognostic favorable (3.19e-4)" "unprognostic (1.84e-1)" "potential prognostic favorable (3.36e-4)" "unprognostic (6.11e-2)" "unprognostic (3.27e-1)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.35e-1)" "unprognostic (5.80e-2)" "unprognostic (1.59e-2)" "unprognostic (1.14e-1)" "unprognostic (6.49e-3)" "unprognostic (2.89e-1)" "unprognostic (1.03e-2)" "unprognostic (1.26e-1)" "unprognostic (2.62e-1)" "unprognostic (3.18e-1)" "unprognostic (1.10e-1)" "unprognostic (5.43e-2)" "unprognostic (1.82e-1)" "unprognostic (4.46e-3)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.41e-1)" "unprognostic (6.50e-2)" "unprognostic (1.30e-1)" "unprognostic (4.95e-1)" "unprognostic (1.30e-1)" "unprognostic (1.22e-2)" "unprognostic (1.12e-1)" "unprognostic (4.12e-2)" APOBR "APOB100R, APOB48R" ENSG00000184730 "Apolipoprotein B receptor" Q0VD83 16 28494643-28498964 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor Atherosclerosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 32.7;intestine: 24.9;lung: 11.1;lymphoid tissue: 35.2" "Cell type enhanced" "Detected in some" "cDC: 32.5;Colonocytes: 111.2;Goblet cells: 55.4;Hofbauer cells: 33.9;Macrophages: 29.7;Monocyte progenitors: 44.6;monocytes: 54.3;Neutrophil progenitors: 54.6;Neutrophils: 261.5;NK-cells: 32.3;Tuft cells: 46.1" "Cell type enhanced" "Detected in many" "Enterocytes: 111.2;Neutrophils: 261.5" "Group enriched" "Detected in some" 24 "central nervous system macrophage: 10.5;leukocyte: 26.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in some" 7 "Leukemia: 27.3" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Skin - Langerhans cells, Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cell types: 7021031.5;Keratinocytes: 3721839.9;Macrophages: 3505804.0" "Group enriched" "Detected in many" "bone marrow: 36085534.0;lung: 12954406.0;lymphoid tissue: 24032817.9;skin: 47213295.3" "HPA041667, HPA042093, HPA079642" Enhanced Supported "Plasma membrane,Centrosome" NA NA 270000 "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Plasma membrane" Centrosome "HPA041667: , HPA042093: , HPA079642: " "unprognostic (2.65e-2)" "unprognostic (3.50e-1)" "unprognostic (4.47e-2)" "unprognostic (4.42e-2)" "unprognostic (4.53e-3)" "unprognostic (1.28e-1)" "unprognostic (1.97e-3)" "unprognostic (9.85e-3)" "unprognostic (9.86e-2)" "unprognostic (2.51e-2)" "unprognostic (3.76e-1)" "unprognostic (3.87e-3)" "unprognostic (1.13e-1)" "unprognostic (2.09e-2)" "unprognostic (1.51e-2)" "unprognostic (4.92e-2)" "unprognostic (3.63e-1)" "unprognostic (8.86e-2)" "unprognostic (2.51e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-2)" "unprognostic (2.59e-2)" "unprognostic (9.50e-2)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (3.84e-4)" "unprognostic (3.05e-3)" "unprognostic (1.01e-1)" "unprognostic (6.64e-3)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" APOH "B2G1, BG" ENSG00000091583 "Apolipoprotein H" P02749 17 66212033-66256525 "Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Heparin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 564 "liver: 16781.5" "Cell type enriched" "Detected in some" 55 "Hepatocytes: 9195.7" "Cell type enriched" "Detected in many" 55 "Hepatocytes: 9195.7" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 211 "Liver Hepatocellular Carcinoma (TCGA): 4417.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 46 "liver cancer: 154.3" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Alveolar cell types: 97317170.7;Collecting ducts: 44548816.4" "Low tissue specificity" "Detected in all" "HPA001654, HPA003732, CAB022214" Enhanced Supported "Golgi apparatus" "Secreted to blood" Apolipoprotein NA NA 247000000000 58000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 9 "Golgi apparatus" "CAB022214: , HPA001654: , HPA003732: " "unprognostic (5.73e-2)" "unprognostic (1.48e-2)" "unprognostic (1.61e-3)" "unprognostic (2.24e-3)" "unprognostic (2.95e-2)" "potential prognostic favorable (5.45e-7)" "unprognostic (5.16e-3)" "unprognostic (8.40e-2)" "unprognostic (1.83e-1)" "unprognostic (4.58e-3)" "unprognostic (7.44e-3)" "unprognostic (1.84e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (1.06e-2)" "unprognostic (6.63e-3)" "unprognostic (4.33e-2)" "unprognostic (1.06e-1)" APOL4 APOLIV ENSG00000100336 "Apolipoprotein L4" Q9BPW4 22 36189124-36204840 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 18.3;Endometrial glandular cells: 26.8;Endometrial luminal cells: 104.2;Fallopian tube ciliated cells: 48.2;Prostatic club cells: 18.6;Prostatic glandular cells: 29.5;Prostatic hillock cells: 19.1;Somatotrophs: 21.9;Urothelial cells: 16.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 48.2;Luminal cells: 104.2" "Cell type enhanced" "Detected in some" "endothelial cell: 2.4;fibroblast: 5.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Leukemia: 15.5;lymphoma: 4.5" "Minor Salivary Gland - Macrophages, Testis - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049797, HPA055435" Uncertain Supported Vesicles "Secreted to blood" Apolipoprotein NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 13: Lung - Secretion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Vesicles "HPA049797: , HPA055435: " "unprognostic (1.01e-2)" "unprognostic (6.58e-2)" "unprognostic (1.06e-1)" "unprognostic (4.83e-2)" "unprognostic (6.26e-2)" "unprognostic (6.68e-3)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (2.13e-1)" "unprognostic (4.97e-2)" "unprognostic (6.53e-3)" "unprognostic (8.73e-2)" "unprognostic (8.86e-2)" "unprognostic (3.53e-1)" "unprognostic (2.61e-1)" "unprognostic (9.49e-2)" "unprognostic (3.13e-1)" "unprognostic (2.24e-1)" "unprognostic (1.96e-2)" "unprognostic (2.85e-2)" "unprognostic (8.87e-3)" "unprognostic (4.91e-2)" "unprognostic (1.17e-1)" "unprognostic (4.50e-2)" "unprognostic (2.90e-1)" "unprognostic (6.63e-2)" "unprognostic (4.70e-2)" "unprognostic (1.71e-1)" "unprognostic (6.86e-2)" "unprognostic (4.27e-1)" APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 116.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 117.8;Choroid plexus epithelial cells: 137.7;Lymphatic endothelial cells: 254.4;Monocyte progenitors: 171.7;Müller glia: 240.5;Pericytes: 300.8;Retinal pigment epithelial cells: 238.7;Vascular endothelial cells: 308.5;Vascular smooth muscle cells: 367.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 308.5;Glial cells: 240.5;Mural cells: 367.7;Pigment cells: 238.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 166.9;endothelial cell: 270.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 88.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 9 "skin cancer: 43.6" "Breast - Endothelial cells, Prostate - Endothelial cells" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052462, HPA058882" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" "Nucleoplasm, Plasma membrane" "HPA052462: , HPA058882: " "unprognostic (5.17e-3)" "unprognostic (3.19e-1)" "unprognostic (1.54e-2)" "unprognostic (2.03e-2)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "unprognostic (1.51e-1)" "unprognostic (2.09e-1)" "unprognostic (2.57e-2)" "unprognostic (1.65e-1)" "validated prognostic favorable (2.12e-11)" "validated prognostic favorable (2.52e-5)" "unprognostic (4.42e-3)" "unprognostic (2.43e-2)" "unprognostic (7.68e-3)" "unprognostic (7.85e-2)" "unprognostic (2.55e-2)" "unprognostic (1.25e-1)" "unprognostic (2.61e-1)" "unprognostic (6.55e-3)" "unprognostic (2.69e-3)" "unprognostic (5.51e-2)" "unprognostic (2.25e-1)" "unprognostic (4.48e-2)" "unprognostic (2.04e-2)" "unprognostic (1.41e-3)" "unprognostic (3.28e-1)" "unprognostic (6.88e-3)" "unprognostic (1.23e-1)" "unprognostic (2.18e-2)" "unprognostic (1.28e-2)" APRT ENSG00000198931 "Adenine phosphoribosyltransferase" P07741 16 88809339-88811937 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 848.3;Esophageal suprabasal cells: 1171.5" "Cell type enhanced" "Detected in all" "Suprabasal cells: 1171.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA026681 Approved Approved Nucleoplasm,Cytosol NA NA 1200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 6 "Nucleoplasm, Cytosol" "HPA026681: " "unprognostic (9.60e-2)" "unprognostic (3.06e-2)" "unprognostic (6.73e-2)" "unprognostic (3.13e-1)" "unprognostic (1.03e-2)" "unprognostic (1.08e-1)" "unprognostic (3.25e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-2)" "unprognostic (6.07e-2)" "unprognostic (3.91e-3)" "unprognostic (1.62e-2)" "potential prognostic favorable (9.42e-4)" "validated prognostic unfavorable (6.93e-4)" "validated prognostic unfavorable (1.54e-4)" "unprognostic (2.82e-2)" "unprognostic (7.24e-3)" "unprognostic (9.80e-2)" "unprognostic (2.32e-1)" "unprognostic (3.04e-1)" "unprognostic (4.91e-1)" "unprognostic (9.14e-3)" "unprognostic (1.47e-1)" "unprognostic (4.82e-2)" "unprognostic (9.87e-2)" "unprognostic (1.83e-1)" "unprognostic (3.94e-1)" "unprognostic (2.49e-2)" "unprognostic (1.62e-1)" "unprognostic (2.46e-1)" "unprognostic (1.44e-2)" APTX "AOA, AOA1, AXA1, EAOH, EOAHA, FLJ20157" ENSG00000137074 Aprataxin Q7Z2E3 9 32886601-33025130 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Hydrolase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1228907.8" "Tissue enhanced" "Detected in many" "bone marrow: 268403.0;lung: 288882.4" HPA064930 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 "Nucleoplasm, Nucleoli" "HPA064930: " "unprognostic (4.93e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (4.78e-4)" "unprognostic (1.60e-1)" "unprognostic (2.18e-1)" "unprognostic (3.10e-1)" "unprognostic (2.38e-1)" "unprognostic (9.85e-3)" "unprognostic (3.01e-2)" "unprognostic (5.43e-2)" "validated prognostic favorable (1.39e-7)" "validated prognostic favorable (9.97e-4)" "unprognostic (2.60e-3)" "unprognostic (5.81e-2)" "unprognostic (9.46e-2)" "unprognostic (1.35e-1)" "unprognostic (3.57e-2)" "unprognostic (2.10e-2)" "unprognostic (9.86e-3)" "unprognostic (3.74e-2)" "unprognostic (2.23e-1)" "unprognostic (9.74e-3)" "unprognostic (1.32e-2)" "unprognostic (3.19e-1)" "unprognostic (5.56e-2)" "unprognostic (2.92e-1)" "unprognostic (2.85e-2)" "unprognostic (9.03e-2)" "unprognostic (2.13e-1)" "unprognostic (1.50e-1)" "unprognostic (8.45e-3)" AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1457.5;skin 1: 554.4;urinary bladder: 642.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1612.8;Esophageal apical cells: 4827.1;Esophageal basal cells: 3864.2;Esophageal suprabasal cells: 7328.2;Ocular epithelial cells: 1729.1;Prostatic hillock cells: 1115.0;Respiratory basal cells: 1096.3;Respiratory secretory cells: 1045.1;Suprabasal keratinocytes: 2386.4;Urothelial cells: 1101.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 4827.1;Basal cells: 3864.2;Suprabasal cells: 7328.2" "Group enriched" "Detected in some" 4 "hippocampal dentate gyrus: 6.8;leukocyte: 21.1;lower rhombic lip: 16.7" "Group enriched" "Detected in all" 5 "Bladder Urothelial Carcinoma (TCGA): 524.5;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 859.9;Head and Neck Squamous Cell Carcinoma (TCGA): 631.6;Lung Adenocarcinoma (TCGA): 432.7;Lung Squamous Cell Carcinoma (TCGA): 216.3" "Region enhanced" "Detected in all" "pons: 47.2" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 182.0;T-reg: 205.9" "Lineage enriched" "Detected in many" 18 "T-cells: 205.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 403.6" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1682 "Collecting ducts: 168162.7" "Not detected" "Not detected" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 23 "Plasma membrane" "HPA014924: " "unprognostic (1.80e-3)" "unprognostic (7.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.02e-3)" "unprognostic (4.94e-2)" "unprognostic (3.32e-2)" "unprognostic (5.08e-3)" "unprognostic (1.60e-1)" "unprognostic (1.49e-2)" "unprognostic (1.88e-1)" "unprognostic (4.49e-3)" "unprognostic (3.47e-3)" "unprognostic (1.28e-1)" "unprognostic (8.21e-2)" "unprognostic (2.75e-1)" "unprognostic (4.24e-3)" "unprognostic (2.18e-2)" "unprognostic (7.24e-3)" "unprognostic (2.74e-1)" "unprognostic (1.42e-1)" "unprognostic (3.46e-2)" "unprognostic (1.60e-2)" "unprognostic (1.59e-1)" "unprognostic (1.23e-1)" "unprognostic (7.32e-2)" "unprognostic (2.92e-3)" "unprognostic (2.70e-1)" "unprognostic (2.77e-2)" "unprognostic (2.59e-1)" "unprognostic (4.26e-2)" "unprognostic (7.73e-2)" AQP4 "AQP-4, hAQP4, MIWC" ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 354.4;lung: 108.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 568.4;Alveolar cells type 2: 318.0;Astrocytes: 742.9;Bergmann glia: 125.9;Ependymal cells: 261.0;Müller glia: 226.5;Parietal cells: 123.8;Transitional alveolar cells: 392.4" "Group enriched" "Detected in many" 4 "Alveolar cells: 568.4;Ciliated cells: 261.0;Glial cells: 742.9" "Cell type enhanced" "Detected in many" "astrocyte: 951.4;Bergmann glia: 217.4;ependymal cell: 376.8" "Cancer enriched" "Detected in some" 16 "Glioblastoma Multiforme (TCGA): 397.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Brain cancer: 2.5;Rhabdoid: 1.7" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Astrocytes and Neuropil: 55326466.3" "Tissue enriched" "Detected in some" "cerebral cortex: 82884547.2" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 4 "Plasma membrane" "Cell Junctions" "CAB005079: , CAB058689: , HPA014784: " "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (3.94e-7)" "unprognostic (1.34e-3)" "unprognostic (7.21e-3)" "unprognostic (8.03e-2)" "unprognostic (4.87e-3)" "unprognostic (3.68e-1)" "unprognostic (9.85e-2)" AQR "fSAP164, IBP160, KIAA0560" ENSG00000021776 "Aquarius intron-binding spliceosomal factor" O60306 15 34851782-34969742 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "intestine: 5715570.8;lymphoid tissue: 9270019.1;pancreas: 18329964.8" "HPA040624, HPA055647" Enhanced Nucleoplasm No No "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 85 Nucleoplasm "HPA040624: , HPA055647: " "unprognostic (7.05e-2)" "unprognostic (6.74e-3)" "unprognostic (1.76e-1)" "unprognostic (2.19e-1)" "unprognostic (7.75e-2)" "unprognostic (5.35e-2)" "unprognostic (2.93e-2)" "unprognostic (1.45e-2)" "unprognostic (1.37e-1)" "unprognostic (2.52e-1)" "validated prognostic favorable (2.22e-7)" "validated prognostic favorable (1.82e-5)" "unprognostic (1.84e-2)" "unprognostic (2.78e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" "unprognostic (4.78e-1)" "unprognostic (3.22e-2)" "unprognostic (4.32e-2)" "unprognostic (4.16e-2)" "unprognostic (7.56e-2)" "unprognostic (2.52e-1)" "unprognostic (6.74e-3)" "unprognostic (7.31e-2)" "unprognostic (5.39e-2)" "unprognostic (3.67e-1)" "unprognostic (2.40e-1)" "unprognostic (3.44e-2)" "unprognostic (1.81e-1)" "unprognostic (6.68e-2)" "unprognostic (6.90e-2)" AREG "AR, AREGB, SDGF" ENSG00000109321 Amphiregulin P15514 4 74445136-74455005 "Cancer-related genes, Human disease related genes, Predicted membrane proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 122.6;placenta: 308.9;urinary bladder: 135.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 3209.8;Breast hormone-responsive cells: 1337.5;cDC: 1501.6;Esophageal apical cells: 1903.7;Hematopoietic stem cells: 1321.3;Innate lymphoid cells: 3588.5;Mast cells: 5140.6;monocytes: 1830.5;NK-cells: 1412.3;Ocular epithelial cells: 2320.0;Thymocytes: 1815.0;Urothelial cells: 1489.4" "Cell type enhanced" "Detected in many" "Basal cells: 3209.8;Innate lymphoid cells: 3588.5;Mast cells: 5140.6" "Cell type enriched" "Detected in some" 17 "leukocyte: 41.6" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 166.5" "Region enhanced" "Detected in some" "choroid plexus: 3.2" "Group enriched" "Detected in some" 11 "basophil: 11.0;eosinophil: 11.8;NK-cell: 3.8" "Group enriched" "Detected in many" 10 "granulocytes: 11.8;NK-cells: 3.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 543.3" "Colon - Neutrophils, Testis - Early spermatids" "Region enriched" "Detected in single" 4 "olfactory bulb: 1.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008720, CAB023519" Approved Approved Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 Mitochondria "CAB023519: , HPA008720: " "unprognostic (8.37e-2)" "unprognostic (3.90e-2)" "unprognostic (1.08e-1)" "unprognostic (1.13e-1)" "unprognostic (5.19e-2)" "unprognostic (1.94e-3)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (6.34e-5)" "unprognostic (1.31e-3)" "unprognostic (3.98e-2)" "unprognostic (3.01e-3)" "unprognostic (2.72e-1)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (8.29e-5)" "unprognostic (3.73e-3)" "unprognostic (5.12e-2)" "unprognostic (1.29e-1)" "validated prognostic unfavorable (6.75e-4)" "validated prognostic unfavorable (4.30e-4)" "unprognostic (3.09e-2)" "unprognostic (2.52e-1)" "potential prognostic favorable (2.36e-4)" "unprognostic (4.21e-1)" "unprognostic (6.66e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-1)" ARFGAP1 "ARF1GAP, bA261N11.3, FLJ10767" ENSG00000101199 "ADP ribosylation factor GTPase activating protein 1" Q8N6T3 20 63272785-63289790 "Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Somatotrophs: 90.7" "Cell type enhanced" "Detected in many" "Pituitary endocrine cells: 90.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 7142086.0;Microglia and Neuropil: 9358968.4" "Tissue enhanced" "Detected in many" "cerebral cortex: 73557826.0;intestine: 81612948.4" "HPA051019, HPA056273" Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Primary cilium,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 16 "Golgi apparatus" "Nuclear membrane, Vesicles, Primary cilium, Cytosol" "HPA051019: , HPA056273: " "unprognostic (5.44e-2)" "unprognostic (5.30e-3)" "unprognostic (1.03e-1)" "unprognostic (8.51e-3)" "unprognostic (3.62e-1)" "unprognostic (1.87e-1)" "unprognostic (3.91e-1)" "unprognostic (6.00e-3)" "unprognostic (1.73e-2)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (1.96e-5)" "unprognostic (1.94e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.38e-6)" "unprognostic (3.49e-2)" "unprognostic (3.64e-1)" "unprognostic (1.05e-2)" "unprognostic (6.76e-2)" "unprognostic (1.50e-2)" "unprognostic (2.11e-1)" "unprognostic (3.74e-2)" "potential prognostic favorable (6.99e-4)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (1.63e-2)" "unprognostic (1.49e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (1.34e-1)" "unprognostic (9.17e-2)" "unprognostic (1.67e-1)" "unprognostic (1.31e-2)" "unprognostic (1.33e-1)" ARFRP1 "ARL18, ARP, Arp1" ENSG00000101246 "ADP ribosylation factor related protein 1" Q13795 20 63698642-63708025 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Pancreas epithelial cells: 1215361.9;Pancreatic islets: 3138981.2" "Group enriched" "Detected in some" "intestine: 65839.9;salivary gland: 53821.3" "HPA047028, HPA050634" Approved Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 4 "Golgi apparatus" "HPA047028: , HPA050634: " "unprognostic (4.16e-2)" "unprognostic (1.85e-1)" "unprognostic (1.99e-2)" "unprognostic (1.92e-1)" "unprognostic (2.18e-1)" "unprognostic (1.10e-1)" "unprognostic (1.98e-3)" "unprognostic (6.60e-2)" "unprognostic (9.05e-2)" "unprognostic (8.08e-2)" "unprognostic (7.22e-3)" "unprognostic (5.43e-2)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (7.31e-5)" "unprognostic (9.83e-2)" "unprognostic (1.66e-2)" "unprognostic (1.17e-1)" "unprognostic (1.71e-2)" "unprognostic (1.12e-1)" "unprognostic (1.34e-2)" "unprognostic (1.23e-1)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (9.14e-4)" "unprognostic (2.50e-2)" "unprognostic (9.08e-2)" "unprognostic (5.78e-2)" "unprognostic (1.34e-1)" "unprognostic (2.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" ARGLU1 FLJ10154 ENSG00000134884 "Arginine and glutamate rich 1" Q9NWB6 13 106541673-106568137 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA034962, HPA056792" Supported Enhanced Nucleoplasm,Mitochondria,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 35 Nucleoplasm "Mitochondria, Cytosol" "HPA034962: , HPA056792: " "unprognostic (3.12e-2)" "unprognostic (3.64e-1)" "unprognostic (2.40e-1)" "unprognostic (3.12e-3)" "unprognostic (1.55e-2)" "unprognostic (1.92e-1)" "unprognostic (1.26e-2)" "unprognostic (6.25e-3)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (7.72e-2)" "unprognostic (1.37e-2)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (3.20e-1)" "unprognostic (3.38e-1)" "unprognostic (2.92e-1)" "unprognostic (4.17e-3)" "unprognostic (3.97e-2)" "unprognostic (2.14e-1)" "unprognostic (3.55e-1)" "potential prognostic favorable (6.88e-4)" "unprognostic (5.45e-2)" "unprognostic (1.31e-1)" "unprognostic (3.22e-2)" "unprognostic (2.95e-2)" "unprognostic (4.00e-2)" "unprognostic (7.67e-2)" "unprognostic (3.81e-2)" "unprognostic (3.55e-2)" "unprognostic (6.50e-2)" ARHGAP1 "CDC42GAP, p50rhoGAP, RhoGAP" ENSG00000175220 "Rho GTPase activating protein 1" Q07960 11 46677080-46700619 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 147.2" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "oligodendrocyte: 147.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA004689, HPA008285" Approved Approved Supported "Vesicles,Primary cilium,Cytosol" NA NA 3900000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 110: Mural cells - ECM organization" 29 Cytosol "Vesicles, Primary cilium" "HPA004689: , HPA008285: " "unprognostic (8.69e-3)" "unprognostic (1.51e-1)" "unprognostic (1.59e-1)" "unprognostic (5.56e-2)" "unprognostic (1.35e-2)" "unprognostic (1.77e-3)" "unprognostic (6.97e-3)" "unprognostic (7.01e-2)" "unprognostic (1.93e-1)" "unprognostic (4.41e-2)" "unprognostic (3.28e-2)" "unprognostic (2.57e-1)" "unprognostic (9.01e-3)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (1.10e-1)" "unprognostic (1.21e-2)" "potential prognostic unfavorable (5.47e-7)" "unprognostic (2.26e-2)" "unprognostic (5.06e-2)" "unprognostic (2.57e-2)" "unprognostic (7.64e-2)" "unprognostic (7.06e-2)" "unprognostic (4.33e-1)" "unprognostic (3.01e-1)" "unprognostic (5.99e-2)" "unprognostic (8.47e-2)" "unprognostic (2.18e-2)" "unprognostic (1.05e-2)" "unprognostic (3.01e-1)" "unprognostic (8.58e-2)" "unprognostic (7.68e-2)" ARHGAP11A KIAA0013 ENSG00000198826 "Rho GTPase activating protein 11A" Q6P4F7 15 32615144-32639941 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.5;lymphoid tissue: 24.2" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 3.4;Megakaryocyte progenitors: 3.1;Microglia: 2.1;Monocyte progenitors: 4.7;Neutrophil progenitors: 1.9;Oligodendrocytes: 1.3;Papillary tip epithelial cells: 2.0;Renal collecting duct principal cells: 1.4;Renal connecting tubule cells: 1.0" "Cell type enhanced" "Detected in some" "Erythrocytes: 3.4;Glial cells: 2.1;Megakaryocytes: 3.1;Mononuclear phagocytes: 4.7;Renal nephron cells: 2.0" "Cell type enhanced" "Detected in many" "leukocyte: 6.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Macrophages, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 84 "Granulosa cells: 8424.7" "Not detected" "Not detected" "HPA040830, HPA066481" Enhanced Approved Nucleoli,Cytosol No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 9 Cytosol Nucleoli "HPA040830: , HPA066481: " "unprognostic (4.83e-2)" "unprognostic (1.48e-1)" "unprognostic (3.77e-2)" "unprognostic (4.01e-1)" "unprognostic (6.27e-2)" "unprognostic (4.11e-1)" "unprognostic (2.11e-1)" "unprognostic (1.56e-2)" "unprognostic (1.40e-1)" "unprognostic (4.43e-3)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (2.28e-5)" "unprognostic (3.96e-3)" "potential prognostic unfavorable (1.58e-5)" "potential prognostic unfavorable (3.56e-5)" "unprognostic (1.98e-3)" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "unprognostic (1.25e-1)" "unprognostic (7.12e-2)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (4.73e-3)" "unprognostic (5.09e-2)" "unprognostic (8.58e-3)" "unprognostic (4.70e-2)" "unprognostic (1.68e-1)" "unprognostic (1.60e-1)" "unprognostic (6.13e-2)" "unprognostic (1.48e-2)" "unprognostic (1.57e-2)" ARHGAP19 "FLJ00194, MGC14258" ENSG00000213390 "Rho GTPase activating protein 19" Q14CB8 10 97222173-97292673 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.4;Early primary spermatocytes: 2.1;Early spermatids: 3.0;Erythrocyte progenitors: 3.6;Erythrocytes: 3.0;Late primary spermatocytes: 1.3;Late spermatids: 2.8;Monocyte progenitors: 2.8;Neutrophil progenitors: 1.5;Oocytes: 4.6;Platelets: 1.4;Schwann cells: 1.7" "Cell type enhanced" "Detected in some" "Erythrocytes: 3.6;Mononuclear phagocytes: 2.8;Oocytes: 4.6;Spermatogenic cell types: 3.0" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Pancreas - Endothelial cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035777, HPA043231" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 10 "Plasma membrane" "HPA035777: , HPA043231: " "unprognostic (1.68e-2)" "unprognostic (4.45e-1)" "unprognostic (5.90e-2)" "unprognostic (1.85e-1)" "unprognostic (3.81e-1)" "unprognostic (3.41e-2)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-2)" "potential prognostic favorable (1.60e-5)" "unprognostic (2.70e-3)" "unprognostic (1.40e-1)" "unprognostic (1.45e-1)" "unprognostic (2.40e-1)" "unprognostic (7.72e-3)" "unprognostic (3.08e-1)" "unprognostic (2.95e-2)" "unprognostic (2.24e-2)" "unprognostic (3.43e-2)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" "unprognostic (1.32e-2)" "unprognostic (3.12e-1)" "unprognostic (7.96e-2)" "unprognostic (1.83e-1)" "unprognostic (1.69e-1)" "unprognostic (3.10e-2)" ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 307.8;Loop of henle epithelial cells: 487.9;Lymphatic endothelial cells: 589.9;Podocytes: 400.6;Renal connecting tubule cells: 414.5;Vascular endothelial cells: 544.4" "Cell type enhanced" "Detected in all" "Endothelial cells: 589.9;Renal nephron cells: 487.9" "Cell type enhanced" "Detected in many" "endothelial cell: 847.4;fibroblast: 1091.2;pericyte: 1467.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 665074.0;Collecting ducts: 519960.1;Glomeruli: 605719.4" "Tissue enriched" "Detected in many" "kidney: 3112343.2" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: " "unprognostic (7.13e-2)" "unprognostic (7.40e-2)" "unprognostic (2.31e-1)" "unprognostic (1.74e-3)" "unprognostic (1.87e-1)" "unprognostic (6.49e-2)" "unprognostic (1.58e-2)" "unprognostic (9.07e-3)" "unprognostic (2.56e-2)" "unprognostic (4.56e-3)" "potential prognostic favorable (7.80e-5)" "unprognostic (6.95e-3)" "unprognostic (2.58e-2)" "unprognostic (5.51e-2)" "unprognostic (3.59e-2)" "unprognostic (2.51e-1)" "unprognostic (2.59e-2)" "unprognostic (1.15e-1)" "unprognostic (3.18e-1)" "unprognostic (6.73e-3)" "unprognostic (1.24e-1)" "unprognostic (2.65e-3)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (3.74e-1)" "unprognostic (1.80e-1)" "unprognostic (4.16e-1)" "unprognostic (1.44e-1)" "unprognostic (8.58e-3)" "unprognostic (2.97e-1)" "unprognostic (1.45e-1)" "unprognostic (5.04e-3)" ARHGAP32 "GC-GAP, GRIT, KIAA0712, MGC1892, RICS" ENSG00000134909 "Rho GTPase activating protein 32" A7KAX9 11 128965060-129279324 "Cancer-related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Müller glia: 707.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 8966847.1" "Group enriched" "Detected in many" "cerebral cortex: 7890810.4;skeletal muscle: 8207642.0" "HPA038382, HPA038389, HPA061505" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 51 "Golgi apparatus" "Nucleoplasm, Nucleoli fibrillar center, Cytosol" "HPA038382: , HPA038389: , HPA061505: " "unprognostic (1.04e-2)" "unprognostic (3.28e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (3.69e-1)" "unprognostic (1.73e-1)" "unprognostic (4.01e-2)" "unprognostic (2.44e-3)" "unprognostic (6.08e-2)" "unprognostic (8.94e-2)" "potential prognostic favorable (5.22e-7)" "unprognostic (4.28e-3)" "unprognostic (1.26e-1)" "unprognostic (1.20e-1)" "unprognostic (7.69e-3)" "unprognostic (5.22e-2)" "unprognostic (1.58e-2)" "unprognostic (1.47e-1)" "unprognostic (3.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (6.60e-3)" "unprognostic (1.85e-1)" "unprognostic (2.43e-3)" "unprognostic (7.17e-2)" "unprognostic (4.59e-2)" "unprognostic (6.00e-2)" "unprognostic (2.75e-1)" "unprognostic (9.67e-3)" "unprognostic (2.17e-1)" ARHGAP36 FLJ30058 ENSG00000147256 "Rho GTPase activating protein 36" Q6ZRI8 X 131058346-131089885 "Predicted intracellular proteins" "GTPase activation" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "adrenal gland: 99.5;brain: 77.0;pituitary gland: 166.5" "Group enriched" "Detected in some" 18 "Adrenal medulla cells: 138.3;Lactotrophs: 150.5;Other brain neurons: 38.0;Somatotrophs: 41.7;Thymic myoid cells: 68.0;Thyrotrophs: 106.1" "Group enriched" "Detected in some" 20 "Adrenal endocrine cells: 138.3;Neuronal cells: 38.0;Pituitary endocrine cells: 150.5;Stromal cells: 68.0" "Cell type enhanced" "Detected in some" "amygdala excitatory: 8.3;splatter: 9.9" "Cancer enriched" "Detected in some" 18 "Thyroid Carcinoma (TCGA): 113.7" "Region enhanced" "Detected in all" "hypothalamus: 284.2;pons: 310.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Neuroblastoma: 37.1" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes, Testis - Spermatogonia" "Region enhanced" "Detected in many" "hypothalamus: 89.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002064, HPA076209" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" Yes NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 Nucleoplasm "Vesicles, Plasma membrane" "HPA002064: , HPA076209: " "unprognostic (1.16e-2)" "unprognostic (1.76e-1)" "unprognostic (5.02e-2)" "potential prognostic favorable (5.40e-4)" "unprognostic (2.38e-1)" ARHGAP4 "C1, KIAA0131, p115, RhoGAP4, SrGAP4" ENSG00000089820 "Rho GTPase activating protein 4" P98171 X 153907367-153934999 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.5;lymphoid tissue: 114.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;B-cells: 39.2;cDC: 28.7;Hematopoietic stem cells: 32.5;Hofbauer cells: 28.3;Kupffer cells: 27.7;Macrophages: 34.0;Microglia: 30.2;Monocyte progenitors: 28.6;Neutrophil progenitors: 54.3;Neutrophils: 60.7;NK-cells: 28.1;pDCs: 35.5;T-cells: 27.7;Thymocytes: 43.2;Tuft cells: 92.2" "Cell type enhanced" "Detected in many" "Neutrophils: 60.7;Secretory gland support: 92.2" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 38.5;choroid plexus epithelial cell: 20.8;leukocyte: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 90.9;Myeloma: 97.2" "Skeletal muscle - Macrophages, Thyroid gland - T-cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 17210189.9;Macrophages: 57364274.4;T-cells: 25949797.7" "Tissue enhanced" "Detected in many" "bone marrow: 20841316.6;lymphoid tissue: 31192582.4" "HPA000301, HPA001012, HPA001083" Enhanced Supported Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 Cytosol "HPA000301: , HPA001012: , HPA001083: " "unprognostic (2.68e-1)" "unprognostic (1.88e-2)" "unprognostic (2.19e-1)" "unprognostic (7.73e-2)" "potential prognostic unfavorable (1.34e-4)" "unprognostic (3.85e-2)" "unprognostic (7.51e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (2.41e-5)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (1.75e-4)" "unprognostic (2.79e-2)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (1.51e-1)" "unprognostic (4.32e-2)" "unprognostic (5.50e-2)" "unprognostic (2.74e-1)" "unprognostic (3.14e-1)" "unprognostic (2.30e-1)" "unprognostic (2.62e-1)" "unprognostic (2.05e-2)" "unprognostic (1.44e-2)" "unprognostic (2.88e-1)" "unprognostic (7.39e-2)" "unprognostic (1.27e-1)" "unprognostic (5.38e-2)" "unprognostic (2.74e-2)" "unprognostic (5.44e-2)" "unprognostic (1.35e-1)" "unprognostic (1.99e-1)" ARHGAP40 "C20orf95, dJ1100H13.4" ENSG00000124143 "Rho GTPase activating protein 40" Q5TG30 20 38601809-38651035 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in many" 4 "breast: 28.5;epididymis: 33.6;esophagus: 25.1;skin 1: 42.4" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 38.0;Early spermatids: 20.9;Ependymal cells: 10.9;Epididymal principal cells: 15.7;Esophageal apical cells: 116.2;Late spermatids: 10.7;Papillary tip epithelial cells: 12.6;Prostatic glandular cells: 17.1;Urothelial cells: 16.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 116.2;Luminal cells: 38.0" "Cell type enhanced" "Detected in some" "ependymal cell: 11.7;medium spiny neuron: 3.6" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 14.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.8" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 576 "Skeletal myofibers: 57571.4" "Not detected" "Not detected" "HPA042636, HPA042840" Uncertain Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" No NA "Cluster 58: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA042636: , HPA042840: " "unprognostic (1.76e-1)" "unprognostic (2.19e-2)" "unprognostic (7.59e-2)" "unprognostic (2.14e-1)" "unprognostic (1.70e-1)" "unprognostic (1.18e-3)" "unprognostic (7.84e-2)" "unprognostic (3.05e-3)" "unprognostic (7.01e-2)" "unprognostic (1.18e-2)" "unprognostic (1.21e-2)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (1.72e-6)" "unprognostic (6.05e-2)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (2.46e-1)" "unprognostic (1.01e-2)" ARHGAP6 rhoGAPX-1 ENSG00000047648 "Rho GTPase activating protein 6" O43182 X 11117651-11665920 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 2375.4;Loop of henle epithelial cells: 984.8;Mesothelial cells: 737.6;Pericytes: 544.2;Platelets: 543.3;Prostatic glandular cells: 1520.0;Proximal tubule cells: 789.2;Renal collecting duct intercalated cells: 519.9;Renal collecting duct principal cells: 571.2;Renal connecting tubule cells: 876.1" "Cell type enhanced" "Detected in many" "Glandular cells: 1520.0;Renal nephron cells: 2375.4" "Cell type enhanced" "Detected in all" "pericyte: 708.4;vascular associated smooth muscle cell: 592.5" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 32.2;Prostate Adenocarcinoma (TCGA): 32.6;Thyroid Carcinoma (TCGA): 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "prostate cancer: 22.1" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Collecting ducts: 3490225.6;Distal tubules: 2849023.6;Oocytes: 2079953.0;Smooth muscle cells: 4020864.7;T-cells: 1495356.3" "Tissue enhanced" "Detected in many" "intestine: 2776809.5" "HPA001798, HPA002715, HPA036779, HPA064390" Enhanced Supported "Mitotic spindle,Cytosol" Yes NA 190000 "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" Cytosol "Mitotic spindle" "HPA001798: , HPA002715: , HPA036779: , HPA064390: " "unprognostic (5.69e-2)" "unprognostic (9.96e-2)" "unprognostic (1.59e-1)" "unprognostic (5.04e-2)" "unprognostic (6.14e-2)" "unprognostic (7.09e-3)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "validated prognostic favorable (7.27e-10)" "validated prognostic favorable (8.86e-4)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (6.74e-2)" "unprognostic (6.13e-2)" "unprognostic (6.22e-2)" "unprognostic (5.27e-3)" "unprognostic (1.95e-2)" "unprognostic (2.83e-1)" "unprognostic (1.62e-1)" "unprognostic (1.72e-1)" "unprognostic (4.73e-3)" "unprognostic (1.38e-2)" "unprognostic (9.74e-2)" "unprognostic (2.82e-2)" ARHGDIB "GDIA2, GDID4, Ly-GDI, RAP1GN1, RhoGDI2" ENSG00000111348 "Rho GDP dissociation inhibitor beta" P52566 12 14942031-14961728 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 1491.2;lymphoid tissue: 1001.9" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1010.2;Hofbauer cells: 1168.4;Kupffer cells: 775.9;Mast cells: 850.9;Megakaryocyte progenitors: 604.4;Megakaryocytes: 1335.2;Monocyte progenitors: 708.7;monocytes: 625.7;Neutrophil progenitors: 912.1;Neutrophils: 1322.1;NK-cells: 536.7;Platelets: 1664.1;T-cells: 718.7" "Cell type enhanced" "Detected in many" "Megakaryocytes: 1335.2;Mononuclear phagocytes: 1168.4;Neutrophils: 1322.1;Platelets: 1664.1;Trophoblast cells: 1010.2" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 129.1;leukocyte: 206.7;pericyte: 87.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 1348.1;lymphoma: 998.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 73253099.1;Macrophages: 61862356.0;T-cells: 90438586.8" "Group enriched" "Detected in all" "bone marrow: 742357737.9;lymphoid tissue: 356046247.0" "CAB018584, HPA051235" Enhanced Supported Cytosol NA NA 41000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 9 Cytosol "CAB018584: , HPA051235: " "unprognostic (4.53e-3)" "unprognostic (4.47e-3)" "unprognostic (1.72e-2)" "unprognostic (1.44e-1)" "unprognostic (7.78e-2)" "unprognostic (2.78e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (5.83e-3)" "unprognostic (1.59e-1)" "unprognostic (5.56e-2)" "unprognostic (2.90e-2)" "unprognostic (4.93e-2)" "unprognostic (2.46e-1)" "unprognostic (1.36e-1)" "unprognostic (4.61e-2)" "unprognostic (3.92e-3)" "unprognostic (2.25e-1)" "unprognostic (1.11e-1)" "unprognostic (1.59e-1)" "unprognostic (6.15e-2)" "unprognostic (8.79e-3)" "unprognostic (7.40e-2)" "unprognostic (7.80e-2)" "unprognostic (1.69e-2)" "unprognostic (1.47e-1)" "unprognostic (2.47e-1)" "unprognostic (9.30e-2)" "unprognostic (3.31e-3)" "unprognostic (2.13e-1)" "unprognostic (3.85e-1)" ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 44.7;breast: 40.8" "Group enriched" "Detected in some" 4 "Lymphatic endothelial cells: 23.2;Vascular endothelial cells: 74.5" "Cell type enriched" "Detected in some" 6 "Endothelial cells: 74.5" "Cell type enriched" "Detected in some" 8 "endothelial cell: 56.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "Sarcoma: 1.3" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Alveolar cell types: 728867.4;Capillaries: 824205.3;Glomeruli: 811302.6;Pancreatic islets: 580005.0;Proximal tubules: 544178.4" "Tissue enriched" "Detected in some" "intestine: 331275.5" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Plasma membrane" "HPA044443: , HPA063495: " "unprognostic (1.44e-1)" "unprognostic (2.19e-1)" "unprognostic (3.16e-2)" "unprognostic (6.77e-3)" "unprognostic (6.74e-2)" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (7.48e-2)" "unprognostic (3.18e-3)" "unprognostic (2.93e-2)" "validated prognostic favorable (3.14e-7)" "validated prognostic favorable (1.72e-4)" "unprognostic (9.51e-3)" "unprognostic (7.04e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (3.45e-2)" "unprognostic (6.21e-2)" "unprognostic (1.49e-2)" "unprognostic (1.45e-1)" "unprognostic (2.76e-1)" "unprognostic (1.20e-1)" "unprognostic (1.89e-2)" "unprognostic (4.36e-2)" "unprognostic (2.85e-2)" "unprognostic (1.97e-2)" "unprognostic (2.68e-1)" "unprognostic (2.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.72e-1)" "unprognostic (3.31e-1)" "unprognostic (5.76e-2)" ARHGEF19 "FLJ33962, WGEF" ENSG00000142632 "Rho guanine nucleotide exchange factor 19" Q8IW93 1 16197854-16212652 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 26.8" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 23.4;Paneth cells: 27.1" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in some" "endothelial cell: 7.2;leukocyte: 5.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Keratinocytes: 105349.4" "Tissue enriched" "Detected in single" 12628 "bone marrow: 1262826.6" HPA068108 Approved "Nuclear bodies" No No "Cluster 33: Non-specific - ATP binding" "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 1 "Nuclear bodies" "HPA068108: " "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (3.32e-1)" "unprognostic (5.17e-2)" "unprognostic (3.72e-1)" "unprognostic (1.84e-2)" "unprognostic (4.92e-2)" "unprognostic (2.98e-3)" "unprognostic (2.34e-3)" "unprognostic (2.70e-2)" "unprognostic (2.74e-2)" "unprognostic (9.07e-2)" "unprognostic (1.67e-2)" "unprognostic (5.27e-2)" "unprognostic (9.30e-2)" "unprognostic (3.62e-2)" "unprognostic (7.04e-2)" "unprognostic (1.70e-1)" "unprognostic (4.33e-2)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (9.80e-3)" "unprognostic (1.88e-1)" "unprognostic (5.49e-2)" "unprognostic (2.17e-1)" "unprognostic (7.04e-2)" "unprognostic (2.60e-3)" ARHGEF6 "alpha-PIX, alphaPIX, Cool-2, Cool2, KIAA0006, MRX46" ENSG00000129675 "Rac/Cdc42 guanine nucleotide exchange factor 6" Q15052 X 136665547-136780932 "Cancer-related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 205.5;Astrocytes: 114.3;Hematopoietic stem cells: 148.0;Mast cells: 249.4;Microglia: 250.7;Monocyte progenitors: 115.7;Myonuclei: 183.8;Neutrophil progenitors: 197.2;Thymocytes: 112.6" "Cell type enhanced" "Detected in many" "Adipocytes: 205.5;Glial cells: 250.7;Mast cells: 249.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 311.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 52.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 97.4;lymphoma: 38.7" "Colon - Enteric glia cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 22532603.9;T-cells: 18190770.4" "Low tissue specificity" "Detected in many" "HPA003578, HPA071036" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 38 "Plasma membrane, Cytosol" "HPA003578: , HPA071036: " "unprognostic (5.40e-3)" "unprognostic (1.02e-1)" "unprognostic (1.48e-1)" "unprognostic (3.61e-2)" "unprognostic (5.31e-2)" "unprognostic (4.80e-2)" "unprognostic (1.40e-2)" "unprognostic (8.73e-2)" "unprognostic (2.55e-3)" "unprognostic (6.01e-3)" "unprognostic (4.23e-2)" "unprognostic (2.37e-1)" "unprognostic (2.59e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-2)" "potential prognostic favorable (5.10e-5)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (2.68e-1)" "unprognostic (1.94e-1)" "unprognostic (2.27e-1)" "unprognostic (1.65e-1)" "unprognostic (2.15e-1)" "unprognostic (3.82e-2)" "unprognostic (1.88e-1)" "unprognostic (3.23e-2)" "unprognostic (4.51e-3)" "unprognostic (2.38e-1)" "unprognostic (3.10e-2)" ARL13A ARL13 ENSG00000174225 "ADP ribosylation factor like GTPase 13A" Q5H913 X 100969708-100990831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 4.8" "Group enriched" "Detected in some" 7 "Early spermatids: 72.6;Late primary spermatocytes: 37.5;Late spermatids: 88.9" "Cell type enriched" "Detected in some" 9 "Spermatogenic cell types: 88.9" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA037377, HPA037378" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol,Acrosome,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Non-specific - mRNA processing" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Plasma membrane, Actin filaments, Connecting piece, Mid piece" "Cytosol, Acrosome, Principal piece" "HPA037377: , HPA037378: " "unprognostic (3.82e-1)" "unprognostic (5.50e-2)" ARL13B "ARL2L1, DKFZp761H079, JBTS8" ENSG00000169379 "ADP ribosylation factor like GTPase 13B" Q3SXY8 3 93980139-94055678 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 16.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 317.4;Cone photoreceptor cells: 240.1;Rod photoreceptor cells: 611.1" "Cell type enhanced" "Detected in all" "Ciliated cells: 317.4;Neuronal cells: 611.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 331.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 1096749.8" "Tissue enriched" "Detected in single" 352 "fallopian tube: 35221.4" HPA048926 Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium transition zone,Basal body,Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 8: Immune cells - Immune response" "Cluster 3: Rhabdoid - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 127 "Microtubules, Primary cilium, Primary cilium transition zone" "Cytokinetic bridge, Basal body, Acrosome, Equatorial segment, Mid piece, Principal piece, End piece" "HPA048926: " "unprognostic (8.35e-2)" "unprognostic (1.37e-1)" "unprognostic (3.58e-1)" "unprognostic (1.37e-1)" "unprognostic (3.34e-1)" "unprognostic (3.48e-1)" "unprognostic (1.76e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (6.28e-4)" "potential prognostic favorable (5.08e-5)" "unprognostic (2.21e-1)" "unprognostic (3.00e-2)" "unprognostic (5.47e-2)" "unprognostic (1.68e-1)" "unprognostic (1.82e-1)" "unprognostic (3.26e-1)" "unprognostic (4.20e-2)" "unprognostic (6.73e-2)" "unprognostic (8.04e-3)" "unprognostic (4.45e-3)" "unprognostic (3.90e-3)" "unprognostic (6.68e-2)" "unprognostic (3.49e-1)" "unprognostic (1.42e-2)" "unprognostic (1.35e-1)" "unprognostic (7.18e-2)" "unprognostic (1.01e-1)" "unprognostic (4.44e-2)" "unprognostic (4.58e-2)" ARL15 "ARFRP2, FLJ20051" ENSG00000185305 "ADP ribosylation factor like GTPase 15" Q9NXU5 5 53883942-54310582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1518.6;Renal collecting duct intercalated cells: 2219.9;Renal connecting tubule cells: 3279.9;Sertoli cells: 2305.2;Vascular endothelial cells: 1393.6" "Cell type enhanced" "Detected in all" "Ductal cells: 3279.9;Reproductive supporting cells: 2305.2" "Cell type enhanced" "Detected in all" "endothelial cell: 3123.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Skin - Outer root sheath cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 4357622.6" "Tissue enhanced" "Detected in many" "bone marrow: 4377884.8;cerebral cortex: 5133052.4" HPA044604 Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 28: Neutrophils - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 17 "Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Basal body" "HPA044604: " "unprognostic (6.37e-2)" "unprognostic (3.63e-1)" "unprognostic (1.80e-2)" "unprognostic (2.46e-3)" "unprognostic (1.84e-2)" "unprognostic (4.34e-2)" "unprognostic (3.02e-1)" "unprognostic (5.04e-2)" "unprognostic (1.09e-1)" "unprognostic (5.71e-2)" "potential prognostic favorable (2.64e-10)" "unprognostic (2.76e-3)" "unprognostic (3.15e-1)" "unprognostic (3.04e-2)" "unprognostic (9.33e-2)" "unprognostic (4.74e-1)" "unprognostic (5.52e-1)" "unprognostic (5.24e-2)" "unprognostic (1.24e-1)" "unprognostic (8.89e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.53e-3)" "unprognostic (2.54e-1)" "unprognostic (3.21e-1)" "unprognostic (1.05e-1)" "unprognostic (2.15e-1)" "unprognostic (5.48e-3)" "unprognostic (1.54e-1)" "unprognostic (2.18e-1)" "unprognostic (7.00e-3)" "unprognostic (5.09e-2)" ARL16 ENSG00000214087 "ADP ribosylation factor like GTPase 16" 17 81681187-81683797 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043711 Uncertain Approved "Primary cilium,Basal body" NA NA "Cluster 32: Basophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" "Primary cilium, Basal body" "HPA043711: " "unprognostic (2.82e-2)" "unprognostic (1.02e-1)" "unprognostic (3.47e-1)" "unprognostic (1.12e-1)" "unprognostic (4.60e-1)" "unprognostic (4.67e-2)" "unprognostic (1.41e-1)" "unprognostic (8.40e-2)" "unprognostic (9.61e-2)" "unprognostic (1.50e-3)" "potential prognostic favorable (3.34e-4)" "unprognostic (5.72e-3)" "unprognostic (8.78e-3)" "unprognostic (1.80e-3)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (2.08e-1)" "unprognostic (3.95e-2)" "unprognostic (7.95e-2)" "unprognostic (1.39e-1)" "unprognostic (6.07e-3)" "unprognostic (1.75e-1)" "unprognostic (3.29e-3)" "unprognostic (9.67e-3)" "unprognostic (4.59e-1)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (9.58e-6)" "unprognostic (9.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.90e-1)" "unprognostic (1.43e-1)" ARL2 ARFL2 ENSG00000213465 "ADP ribosylation factor like GTPase 2" P36404 11 65014160-65022184 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 77.4;Late spermatids: 290.5" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 290.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 9773247.8" HPA044610 Supported Approved "Nucleoplasm,Nucleoli,Mitochondria,Basal body,Equatorial segment,Flagellar centriole,Mid piece" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 35 "Nucleoplasm, Basal body, Flagellar centriole" "Nucleoli, Mitochondria, Equatorial segment, Mid piece" "HPA044610: " "unprognostic (6.74e-2)" "unprognostic (6.35e-2)" "unprognostic (1.70e-1)" "unprognostic (2.08e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-1)" "unprognostic (2.14e-1)" "unprognostic (2.97e-1)" "unprognostic (3.08e-2)" "unprognostic (3.09e-1)" "unprognostic (3.77e-1)" "unprognostic (3.86e-1)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (8.61e-4)" "unprognostic (1.10e-2)" "unprognostic (9.31e-2)" "unprognostic (9.42e-2)" "unprognostic (1.82e-1)" "unprognostic (1.55e-1)" "unprognostic (5.47e-2)" "unprognostic (1.18e-1)" "unprognostic (3.20e-2)" "unprognostic (2.70e-2)" "potential prognostic favorable (6.83e-4)" "unprognostic (2.66e-1)" "unprognostic (2.81e-1)" "unprognostic (9.61e-2)" "unprognostic (3.41e-1)" "unprognostic (2.75e-1)" "unprognostic (2.11e-1)" "unprognostic (5.57e-2)" ARL2BP "BART, BART1, RP66" ENSG00000102931 "ADP ribosylation factor like GTPase 2 binding protein" Q9Y2Y0 16 57245259-57253635 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 318.4;Esophageal apical cells: 216.1;Late spermatids: 811.4" "Group enriched" "Detected in all" 4 "Apical squamous epithelial cells: 216.1;Spermatogenic cell types: 811.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 3799021.3" "Low tissue specificity" "Detected in many" "HPA043066, HPA048440" Approved Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 18 "Nucleoplasm, Cytosol" "Centrosome, Basal body" "HPA043066: , HPA048440: " "unprognostic (1.45e-2)" "unprognostic (1.29e-2)" "unprognostic (2.41e-1)" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (7.67e-3)" "unprognostic (5.16e-2)" "unprognostic (1.83e-1)" "unprognostic (2.62e-3)" "unprognostic (2.09e-1)" "potential prognostic favorable (1.78e-5)" "unprognostic (1.41e-1)" "unprognostic (3.92e-1)" "unprognostic (1.38e-2)" "unprognostic (6.70e-2)" "unprognostic (2.62e-3)" "unprognostic (1.88e-2)" "unprognostic (2.05e-2)" "unprognostic (1.20e-1)" "unprognostic (3.18e-1)" "unprognostic (1.27e-2)" "unprognostic (3.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.36e-2)" "unprognostic (1.12e-1)" "unprognostic (2.75e-2)" "unprognostic (5.44e-2)" "unprognostic (4.55e-3)" "unprognostic (2.62e-1)" "unprognostic (7.61e-3)" "unprognostic (3.20e-1)" ARL3 ARFL3 ENSG00000138175 "ADP ribosylation factor like GTPase 3" P36405 10 102673731-102714397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 89.3" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 280.4;Fallopian tube ciliated cells: 402.8;Respiratory ciliated cells: 306.0;Rod photoreceptor cells: 382.2" "Cell type enhanced" "Detected in all" "Ciliated cells: 402.8;Neuronal cells: 382.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA036292, HPA063596" Approved Supported "Nucleoplasm,Primary cilium,Centrosome,Basal body" NA NA 14000 "Cluster 4: Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 79: Photoreceptor cells - Phototransduction" 42 "Nucleoplasm, Centrosome, Basal body" "Primary cilium" "HPA036292: , HPA063596: " "unprognostic (2.20e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-2)" "potential prognostic favorable (9.09e-4)" "unprognostic (6.81e-2)" "unprognostic (1.65e-1)" "unprognostic (1.15e-1)" "unprognostic (6.12e-3)" "unprognostic (3.86e-2)" "unprognostic (2.85e-1)" "potential prognostic favorable (3.95e-6)" "unprognostic (2.17e-2)" "unprognostic (1.18e-3)" "unprognostic (4.66e-3)" "unprognostic (2.31e-2)" "unprognostic (1.44e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-2)" "unprognostic (4.90e-2)" "unprognostic (2.32e-1)" "unprognostic (1.14e-2)" "unprognostic (1.26e-1)" "unprognostic (5.20e-3)" "unprognostic (5.43e-2)" "unprognostic (1.77e-1)" "unprognostic (3.12e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-2)" "unprognostic (1.34e-2)" "unprognostic (9.14e-2)" "unprognostic (4.12e-2)" ARL6 "BBS3, RP55" ENSG00000113966 "ADP ribosylation factor like GTPase 6" Q9H0F7 3 97764521-97801229 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 134.6;Ependymal cells: 104.4;Respiratory ciliated cells: 136.1;Rod photoreceptor cells: 230.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 136.1;Neuronal cells: 230.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 17.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 3338453.2;Microglia and Neuropil: 2933285.8" "Group enriched" "Detected in many" "cerebral cortex: 1002275.8;fallopian tube: 1593331.0" HPA019361 Approved Approved "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "Microtubules, Primary cilium" "Nucleoplasm, Primary cilium tip, Cytosol" "HPA019361: " "unprognostic (2.51e-1)" "unprognostic (8.75e-3)" "unprognostic (1.97e-2)" "unprognostic (2.82e-2)" "unprognostic (2.75e-1)" "unprognostic (7.61e-2)" "unprognostic (1.82e-1)" "unprognostic (1.36e-1)" "unprognostic (1.78e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (1.48e-7)" "unprognostic (3.69e-2)" "unprognostic (7.74e-3)" "unprognostic (9.35e-2)" "unprognostic (7.17e-2)" "unprognostic (1.28e-1)" "unprognostic (5.95e-2)" "unprognostic (2.61e-1)" "unprognostic (4.96e-2)" "unprognostic (2.46e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (2.34e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (1.76e-1)" "unprognostic (3.41e-2)" "unprognostic (1.73e-1)" "unprognostic (3.25e-2)" "unprognostic (5.04e-2)" ARMCX1 "ALEX1, GASP7" ENSG00000126947 "Armadillo repeat containing X-linked 1" Q9P291 X 101550547-101554700 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 69.4;Melanocytes: 59.8;Ovarian stromal cells: 68.3;Schwann cells: 53.4;Smooth muscle cells: 78.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 7.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Sarcoma: 28.9" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "heart muscle: 2854113.3" "HPA000268, HPA005685, CAB020695" Supported Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 94: Gonadal somatic cells - Mixed function" 6 Mitochondria "Nucleoplasm, Cytosol" "CAB020695: , HPA000268: , HPA005685: " "unprognostic (2.20e-1)" "unprognostic (2.15e-1)" "unprognostic (1.21e-1)" "unprognostic (4.73e-3)" "unprognostic (9.96e-3)" "unprognostic (2.33e-2)" "unprognostic (1.92e-1)" "unprognostic (6.63e-3)" "unprognostic (1.59e-1)" "unprognostic (6.38e-2)" "potential prognostic favorable (2.43e-5)" "unprognostic (8.89e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (2.89e-4)" "unprognostic (4.59e-2)" "unprognostic (6.14e-2)" "unprognostic (4.19e-2)" "unprognostic (2.55e-1)" "unprognostic (7.34e-2)" "unprognostic (7.94e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (9.62e-4)" "unprognostic (1.19e-1)" "unprognostic (2.83e-1)" "unprognostic (9.39e-2)" "unprognostic (2.00e-3)" "unprognostic (2.37e-2)" "unprognostic (3.39e-3)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.26e-2)" ARMCX2 "ALEX2, GASP9, KIAA0512" ENSG00000184867 "Armadillo repeat containing X-linked 2" Q7L311 X 101655281-101659850 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 146.2" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 65.1;Epididymal clear cells: 73.5;Epididymal efferent duct absorptive cells: 54.9;Epididymal principal cells: 144.6;Somatotrophs: 57.1" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 144.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 93.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 83.2" "Adrenal gland - Adrenal cortex cells, Liver - Vascular endothelial cells, Pituitary gland - Somatotropes, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 4674093.1;Smooth muscle cells: 5074831.0" "Tissue enhanced" "Detected in many" "heart muscle: 1422947.8" HPA005761 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 34: B-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" Mitochondria Nucleoplasm "HPA005761: " "unprognostic (6.94e-3)" "unprognostic (9.30e-2)" "unprognostic (2.49e-1)" "unprognostic (3.47e-2)" "unprognostic (2.23e-2)" "unprognostic (2.81e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (1.93e-1)" "unprognostic (1.10e-2)" "potential prognostic favorable (9.43e-4)" "unprognostic (4.09e-1)" "unprognostic (3.87e-3)" "unprognostic (2.38e-2)" "unprognostic (1.31e-2)" "unprognostic (1.24e-1)" "unprognostic (8.23e-3)" "unprognostic (4.68e-2)" "unprognostic (2.78e-1)" "unprognostic (3.49e-1)" "unprognostic (3.49e-1)" "potential prognostic favorable (5.97e-5)" "unprognostic (1.15e-1)" "unprognostic (3.74e-2)" "unprognostic (8.26e-2)" "unprognostic (2.24e-1)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (1.58e-2)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" ARMS2 "ARMD8, LOC387715" ENSG00000254636 "Age-related maculopathy susceptibility 2" P0C7Q2 10 122454653-122457352 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 1.3;testis: 2.7" "Cell type enriched" "Detected in some" 4 "Late spermatids: 103.3" "Cell type enriched" "Detected in some" 9 "Spermatogenic cell types: 103.3" "Cell type enhanced" "Detected in some" "LAMP5-LHX6 and Chandelier: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA067225 Enhanced Approved "Principal piece,End piece" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "End piece" "Principal piece" "HPA067225: " ARPP19 "ARPP-16, ARPP-19, ARPP16, ENSAL" ENSG00000128989 "CAMP regulated phosphoprotein 19" P56211 15 52547045-52569883 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 481.4" "Cell type enriched" "Detected in all" 6 "Late spermatids: 5539.0" "Cell type enriched" "Detected in all" 25 "Spermatogenic cell types: 5539.0" "Cell type enhanced" "Detected in all" "medium spiny neuron: 368.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Skeletal myofibers: 26169653.8" "Tissue enhanced" "Detected in many" "cerebral cortex: 41390189.2" HPA056851 Approved Approved "Nucleoli,Vesicles,Basal body,Cytosol" NA NA 380000 "Cluster 45: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 "Vesicles, Basal body" "Nucleoli, Cytosol" "HPA056851: " "unprognostic (3.88e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-1)" "unprognostic (8.37e-2)" "unprognostic (1.78e-1)" "unprognostic (4.93e-2)" "unprognostic (2.48e-1)" "unprognostic (1.45e-1)" "unprognostic (2.31e-1)" "unprognostic (6.41e-3)" "potential prognostic favorable (1.96e-8)" "unprognostic (2.32e-3)" "unprognostic (4.70e-1)" "unprognostic (7.41e-2)" "unprognostic (5.91e-3)" "unprognostic (5.49e-2)" "unprognostic (9.08e-2)" "unprognostic (2.92e-1)" "unprognostic (4.46e-2)" "unprognostic (9.76e-2)" "unprognostic (5.69e-2)" "unprognostic (7.72e-2)" "unprognostic (1.24e-1)" "unprognostic (2.89e-2)" "unprognostic (4.71e-2)" "unprognostic (6.29e-2)" "unprognostic (8.86e-2)" "unprognostic (1.77e-1)" "unprognostic (1.70e-1)" "unprognostic (2.04e-1)" "unprognostic (1.75e-2)" ARSI "FLJ16069, SPG66" ENSG00000183876 "Arylsulfatase family member I" Q5FYB1 5 150296343-150339307 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.5;Hepatic stellate cells: 25.8;Mast cells: 34.5;Melanocytes: 29.4;Oligodendrocytes: 17.5;pDCs: 25.1;Proximal tubule cells: 34.7;Suprabasal keratinocytes: 11.9" "Cell type enhanced" "Detected in many" "dendritic cells: 25.1;Mast cells: 34.5;Pigment cells: 29.4;Renal nephron cells: 34.7;Stellate cells: 25.8" "Cell type enriched" "Detected in some" 5 "oligodendrocyte: 35.0" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 17.0;Skin Cutaneous Melanoma (TCGA): 17.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 33.8" "Colon - Enteric glia cells, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 1167 "Glomeruli: 116675.3" "Not detected" "Not detected" "HPA038386, HPA038398, HPA077833" Uncertain Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" Enzyme NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 1 "Golgi apparatus" Vesicles "HPA038386: , HPA038398: , HPA077833: " "unprognostic (6.05e-2)" "unprognostic (9.70e-3)" "unprognostic (1.37e-1)" "unprognostic (3.97e-2)" "unprognostic (7.95e-3)" "unprognostic (2.32e-1)" "unprognostic (8.53e-3)" "potential prognostic unfavorable (7.84e-4)" "unprognostic (6.36e-3)" "unprognostic (2.21e-2)" "unprognostic (1.33e-3)" "unprognostic (4.01e-2)" "unprognostic (1.77e-2)" "unprognostic (1.78e-3)" "unprognostic (1.34e-3)" "unprognostic (9.05e-3)" "unprognostic (8.26e-3)" "unprognostic (1.79e-2)" "unprognostic (6.89e-2)" "unprognostic (1.69e-2)" "unprognostic (1.14e-1)" "unprognostic (3.86e-1)" ARSJ FLJ23548 ENSG00000180801 "Arylsulfatase family member J" Q5FYB0 4 113900284-113979727 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 110.2;Endometrial stromal cells: 85.3;Medullary thymic epithelial cells: 79.2;Renal collecting duct intercalated cells: 165.8;Renal collecting duct principal cells: 84.4;Renal connecting tubule cells: 101.2;Salivary ionocytes: 130.6" "Cell type enhanced" "Detected in many" "Ductal cells: 165.8;Ionocytes: 130.6" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 107.0;upper rhombic lip: 139.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 16.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036481, HPA036482" Uncertain Enhanced "Actin filaments" "Secreted in other tissues" Enzyme NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Actin filaments" "HPA036481: , HPA036482: " "unprognostic (1.73e-3)" "unprognostic (1.25e-1)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (3.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.75e-2)" "potential prognostic unfavorable (1.15e-5)" "potential prognostic unfavorable (4.63e-4)" "unprognostic (1.14e-3)" "potential prognostic favorable (1.94e-4)" "unprognostic (8.37e-2)" "unprognostic (7.30e-2)" "unprognostic (2.69e-2)" "unprognostic (1.93e-1)" "unprognostic (1.01e-3)" "unprognostic (1.89e-1)" "unprognostic (1.67e-2)" "unprognostic (8.71e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (3.12e-2)" "unprognostic (1.24e-1)" "unprognostic (3.48e-1)" "unprognostic (2.09e-1)" "unprognostic (2.37e-1)" "unprognostic (5.07e-2)" "unprognostic (3.15e-1)" "unprognostic (1.80e-1)" ARSL "ARSE, CDPX, CDPX1" ENSG00000157399 "Arylsulfatase L" P51690 X 2934045-2968475 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 34.2;liver: 85.2;pancreas: 99.1" "Cell type enhanced" "Detected in many" "Cholangiocytes: 35.1;Colonocytes: 51.3;Enteric stem cells: 105.8;Enteric transient amplifying cells: 79.8;Enterocytes: 48.9;Epididymal clear cells: 38.8;Epididymal efferent duct absorptive cells: 110.3;Hepatocytes: 108.6;Pancreatic acinar cells: 79.6;Pancreatic duct cells: 70.2;Paneth cells: 77.3;Schwann cells: 33.6" "Cell type enhanced" "Detected in many" "Acinar cells: 79.6;Ductal cells: 110.3;Hepatocytes: 108.6;Proliferating cells: 79.8;Secretory gland support: 77.3;Stem cells: 105.8" "Cell type enhanced" "Detected in many" "fibroblast: 22.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 30.8;liver cancer: 33.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 21722812.8;Pancreas epithelial cells: 32034241.4;Pancreatic islets: 29422540.6;Proximal tubules: 12557217.5" "Group enriched" "Detected in some" "liver: 25690480.9;pancreas: 17369694.9" "HPA060518, HPA070651" Approved Supported "Golgi apparatus" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" "Golgi apparatus" "HPA060518: , HPA070651: " "unprognostic (3.76e-2)" "unprognostic (2.15e-1)" "unprognostic (1.02e-1)" "unprognostic (4.75e-3)" "unprognostic (1.11e-2)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (2.41e-5)" "unprognostic (1.10e-1)" "unprognostic (1.81e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (5.03e-2)" "unprognostic (2.25e-1)" "unprognostic (4.00e-1)" "unprognostic (7.45e-2)" "unprognostic (9.06e-2)" "unprognostic (2.46e-2)" "unprognostic (1.39e-1)" "unprognostic (1.74e-1)" "unprognostic (2.87e-1)" "unprognostic (1.42e-3)" "unprognostic (9.09e-2)" "unprognostic (7.56e-2)" "unprognostic (1.30e-2)" "unprognostic (8.45e-2)" "unprognostic (1.08e-1)" "unprognostic (5.85e-2)" ASF1A "CIA, DKFZP547E2110" ENSG00000111875 "Anti-silencing function 1A histone chaperone" Q9Y294 6 118894152-118909171 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 92.7;Oocytes: 345.4" "Cell type enhanced" "Detected in all" "Oocytes: 345.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 321750.4;Oocytes: 209826.2" "Tissue enhanced" "Detected in many" "intestine: 2300997.9" "HPA030502, HPA071495" Enhanced Nucleoplasm No No "Cluster 39: T-cells - T-cell receptor" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 130 Nucleoplasm "HPA030502: , HPA071495: " "unprognostic (9.51e-3)" "unprognostic (1.67e-2)" "unprognostic (2.87e-2)" "unprognostic (1.27e-1)" "unprognostic (3.36e-1)" "unprognostic (2.46e-3)" "unprognostic (2.74e-3)" "unprognostic (1.24e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (1.99e-4)" "potential prognostic favorable (2.22e-5)" "unprognostic (1.02e-2)" "unprognostic (2.61e-3)" "potential prognostic unfavorable (8.64e-8)" "unprognostic (3.86e-1)" "unprognostic (1.89e-1)" "unprognostic (3.23e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-2)" "unprognostic (1.32e-1)" "unprognostic (1.93e-2)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (2.35e-1)" "unprognostic (1.30e-2)" "unprognostic (1.58e-1)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (2.08e-1)" "unprognostic (2.23e-2)" "unprognostic (3.81e-1)" ASH2L "ASH2, ASH2L1, ASH2L2, Bre2" ENSG00000129691 "ASH2 like, histone lysine methyltransferase complex subunit" Q9UBL3 8 38105493-38144076 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 143.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 8479397.9" "Tissue enriched" "Detected in many" "intestine: 8633988.5" HPA042289 Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 84 Nucleoplasm "Plasma membrane" "HPA042289: " "unprognostic (1.27e-3)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (3.78e-2)" "unprognostic (1.62e-3)" "unprognostic (8.52e-2)" "unprognostic (2.75e-1)" "unprognostic (1.27e-3)" "unprognostic (7.33e-2)" "unprognostic (2.62e-3)" "potential prognostic favorable (1.81e-6)" "unprognostic (3.74e-3)" "unprognostic (1.29e-1)" "unprognostic (6.55e-2)" "unprognostic (1.72e-1)" "unprognostic (6.16e-2)" "unprognostic (1.37e-1)" "unprognostic (2.17e-3)" "unprognostic (1.78e-1)" "unprognostic (5.65e-2)" "unprognostic (2.37e-2)" "unprognostic (8.61e-2)" "unprognostic (2.70e-1)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (9.42e-2)" "unprognostic (4.76e-2)" "unprognostic (1.96e-1)" "unprognostic (4.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.97e-1)" ASNS ENSG00000070669 "Asparagine synthetase (glutamine-hydrolyzing)" P08243 7 97851677-97872542 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Asparagine biosynthesis" Ligase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 114.4" "Cell type enhanced" "Detected in some" "Astrocytes: 18.6;Bergmann glia: 16.0;Brain excitatory neurons: 59.7;Brain inhibitory neurons: 50.2;Choroid plexus epithelial cells: 13.1;Ependymal cells: 11.4;Loop of henle epithelial cells: 9.8;Microglia: 10.0;Oligodendrocyte progenitor cells: 31.0;Oligodendrocytes: 21.4;Other brain neurons: 46.1;Podocytes: 17.3;Renal connecting tubule cells: 11.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 13.1;Ductal cells: 11.9;Glial cells: 31.0;Neuronal cells: 59.7;Renal nephron cells: 17.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 6 "B-cells: 9.0;T-cells: 14.2" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Pancreas epithelial cells: 86804804.0;Pancreatic islets: 26226562.7" "Group enriched" "Detected in many" "pancreas: 41726294.4;Stomach: 60836298.6" "HPA004924, HPA029318, HPA064737" Approved Supported Cytosol No No 110000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 98: Neurons - Neurotransmission & signaling" 14 Cytosol "HPA004924: , HPA029318: , HPA064737: " "unprognostic (3.74e-1)" "unprognostic (3.27e-2)" "unprognostic (3.57e-2)" "unprognostic (2.88e-1)" "unprognostic (4.12e-2)" "unprognostic (4.68e-3)" "unprognostic (1.67e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (9.03e-5)" "unprognostic (2.45e-3)" "potential prognostic unfavorable (9.15e-8)" "unprognostic (9.14e-3)" "unprognostic (9.02e-2)" "potential prognostic unfavorable (8.91e-6)" "unprognostic (5.99e-2)" "unprognostic (7.18e-2)" "unprognostic (3.74e-3)" "unprognostic (4.73e-2)" "unprognostic (1.61e-2)" "unprognostic (9.70e-2)" "unprognostic (2.97e-2)" "unprognostic (1.45e-2)" "unprognostic (1.29e-1)" "unprognostic (6.65e-3)" "unprognostic (1.16e-2)" "unprognostic (5.07e-1)" "unprognostic (9.91e-2)" "unprognostic (7.01e-2)" "unprognostic (3.91e-1)" "unprognostic (1.44e-2)" "unprognostic (1.33e-1)" ASPH "BAH, CASQ2BP1, HAAH, JCTN" ENSG00000198363 "Aspartate beta-hydroxylase" Q12797 8 61500556-61714640 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Dioxygenase, Oxidoreductase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 362.0" "Cell type enhanced" "Detected in all" "Adipocytes: 1583.1;Neutrophil progenitors: 899.7;Neutrophils: 2305.7;Ocular epithelial cells: 1020.4" "Cell type enhanced" "Detected in all" "Adipocytes: 1583.1;Neutrophils: 2305.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 34.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA055161, HPA059303" Uncertain Enhanced "Endoplasmic reticulum" NA NA 850000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 24: Neutrophils - Innate immunity signal integration" 77 "Endoplasmic reticulum" "HPA055161: , HPA059303: " "unprognostic (2.94e-2)" "unprognostic (1.80e-2)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (9.40e-7)" "unprognostic (2.05e-1)" "unprognostic (2.56e-2)" "unprognostic (1.84e-1)" "unprognostic (4.53e-1)" "unprognostic (2.37e-2)" "unprognostic (5.99e-3)" "unprognostic (2.04e-2)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (5.81e-6)" "unprognostic (2.33e-2)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (3.07e-5)" "unprognostic (1.82e-1)" "unprognostic (7.08e-2)" "unprognostic (1.12e-1)" "unprognostic (9.13e-2)" "unprognostic (9.51e-3)" "potential prognostic unfavorable (4.57e-5)" "unprognostic (9.22e-3)" "unprognostic (1.67e-1)" "unprognostic (6.92e-2)" "unprognostic (3.04e-1)" "unprognostic (3.03e-2)" "unprognostic (3.03e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-3)" "unprognostic (1.16e-1)" ASRGL1 "ALP, ALP1, FLJ22316" ENSG00000162174 "Asparaginase and isoaspartyl peptidase 1" Q7L266 11 62337448-62393412 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 123.8;cervix: 114.4;testis: 93.5" "Cell type enhanced" "Detected in many" "Early spermatids: 337.0;Endometrial ciliated cells: 384.2;Endometrial glandular cells: 452.0;Endometrial luminal cells: 518.2;Epididymal efferent duct absorptive cells: 668.0;Fallopian secretory cells: 324.9;Fallopian tube ciliated cells: 478.2;Late primary spermatocytes: 1172.3;Late spermatids: 893.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 478.2;Ductal cells: 668.0;Glandular cells: 452.0;Luminal cells: 518.2;Spermatogenic cell types: 1172.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 232.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 279.2;eosinophil: 270.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 279.2" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 42899731.2" "Group enriched" "Detected in all" "cerebral cortex: 65704211.3;fallopian tube: 137765147.8;kidney: 126880231.2" "HPA029725, HPA055572, CAB070192" Enhanced Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Microtubules "Nucleoplasm, Cytokinetic bridge" "CAB070192: , HPA029725: , HPA055572: " "unprognostic (1.43e-2)" "unprognostic (1.08e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-2)" "unprognostic (1.82e-2)" "unprognostic (9.04e-2)" "unprognostic (1.65e-1)" "unprognostic (1.03e-3)" "unprognostic (5.53e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.11e-8)" "unprognostic (9.05e-3)" "potential prognostic favorable (4.71e-6)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (1.00e-3)" "unprognostic (2.12e-2)" "unprognostic (3.39e-1)" "unprognostic (2.35e-1)" "unprognostic (1.86e-2)" "unprognostic (9.16e-2)" "unprognostic (1.75e-1)" "unprognostic (4.31e-1)" "unprognostic (8.29e-3)" "unprognostic (3.61e-1)" "unprognostic (1.09e-1)" "unprognostic (8.18e-3)" "unprognostic (1.81e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (1.73e-1)" "unprognostic (1.78e-2)" ASS1 "ASS, CTLN1" ENSG00000130707 "Argininosuccinate synthase 1" P00966 9 130444961-130501274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 1200.9;liver: 1907.1" "Cell type enhanced" "Detected in many" "Colonocytes: 290.0;Cytotrophoblasts: 239.4;Enterocytes: 617.9;Epididymal principal cells: 269.1;Hepatocytes: 1156.7;Prostatic club cells: 336.6;Prostatic hillock cells: 398.8;Proximal tubule cells: 453.0;Urothelial cells: 407.9" "Cell type enhanced" "Detected in many" "Enterocytes: 617.9;Hepatocytes: 1156.7;Renal nephron cells: 453.0" "Cell type enhanced" "Detected in many" "fibroblast: 42.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 15 "plasmacytoid DC: 1.5" "Lineage enriched" "Detected in single" 15 "dendritic cells: 1.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Glomeruli: 1971649083.8;Hepatocytes: 1541966505.4;Proximal tubules: 2053049434.2" "Tissue enriched" "Detected in all" "liver: 1333875014.3" "HPA020896, HPA020934" Enhanced Supported Nucleoplasm,Cytosol No No 5500000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 40 Cytosol Nucleoplasm "HPA020896: , HPA020934: " "unprognostic (4.68e-2)" "unprognostic (2.61e-2)" "unprognostic (1.52e-2)" "unprognostic (2.52e-2)" "unprognostic (9.73e-2)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (1.01e-2)" "unprognostic (4.27e-3)" "unprognostic (3.34e-1)" "unprognostic (1.35e-3)" "unprognostic (2.77e-1)" "unprognostic (1.94e-1)" "unprognostic (7.62e-3)" "unprognostic (2.32e-2)" "unprognostic (9.92e-3)" "unprognostic (1.63e-1)" "unprognostic (2.26e-1)" "unprognostic (1.90e-1)" "unprognostic (5.63e-3)" "unprognostic (1.41e-1)" "unprognostic (3.86e-2)" "unprognostic (3.39e-3)" "unprognostic (1.49e-1)" "unprognostic (7.40e-3)" "unprognostic (1.53e-1)" "unprognostic (5.30e-2)" "unprognostic (2.38e-2)" "unprognostic (3.27e-2)" "unprognostic (5.83e-2)" "unprognostic (3.85e-2)" ASTN2 KIAA0634 ENSG00000148219 "Astrotactin 2" O75129 9 116423112-117415070 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 670.1;Astrocytes: 734.8;Ependymal cells: 909.5;Oligodendrocyte progenitor cells: 1333.0;Pituicytes/FSCs: 2079.4;Prostatic glandular cells: 1015.0;Retinal ganglion cells: 1193.6;Sertoli cells: 977.8" "Cell type enhanced" "Detected in all" "Ciliated cells: 909.5;Glandular cells: 1015.0;Glial cells: 2079.4;Neuronal cells: 1193.6;Reproductive supporting cells: 977.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 56.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 717325.2;Neurons: 516907.7" "Tissue enriched" "Detected in single" 9148 "cerebral cortex: 914798.2" HPA027035 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 39: T-cells - T-cell receptor" "Cluster 35: Non-specific - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Cytosol Nucleoplasm "HPA027035: " "unprognostic (9.67e-2)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (2.38e-1)" "unprognostic (1.73e-2)" "unprognostic (4.90e-2)" "unprognostic (3.45e-1)" "unprognostic (3.86e-3)" "unprognostic (1.26e-2)" "unprognostic (3.94e-1)" "validated prognostic favorable (9.13e-7)" "validated prognostic favorable (3.47e-7)" "potential prognostic favorable (2.86e-5)" "unprognostic (1.31e-1)" "unprognostic (4.50e-3)" "unprognostic (4.91e-2)" "unprognostic (3.83e-1)" "unprognostic (8.37e-2)" "unprognostic (2.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (3.40e-2)" "unprognostic (1.09e-1)" "unprognostic (3.26e-2)" "unprognostic (7.66e-3)" "unprognostic (3.03e-2)" "unprognostic (2.40e-1)" "unprognostic (1.55e-1)" "unprognostic (1.92e-2)" "unprognostic (4.58e-2)" ATAD2 "ANCCA, CT137, DKFZp667N1320, MGC29843, MGC5254, PRO2000" ENSG00000156802 "ATPase family AAA domain containing 2" Q6PL18 8 123319850-123416350 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.0;lymphoid tissue: 26.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 168.5;Erythrocyte progenitors: 342.2;Megakaryocyte progenitors: 229.1;Monocyte progenitors: 345.9;Neutrophil progenitors: 319.9" "Cell type enhanced" "Detected in many" "Erythrocytes: 342.2;Mononuclear phagocytes: 345.9;Neutrophils: 319.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 870030.5;Granulosa cells: 3413761.3;Neutrophils: 959153.4;T-cells: 863869.4" "Tissue enriched" "Detected in some" "bone marrow: 3148044.2" "HPA029424, CAB056158" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 17 Nucleoplasm "CAB056158: , HPA029424: " "unprognostic (2.11e-1)" "unprognostic (1.51e-1)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" "unprognostic (1.20e-2)" "unprognostic (4.27e-1)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (3.16e-2)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (1.04e-9)" "unprognostic (2.72e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (9.64e-3)" "unprognostic (6.30e-2)" "unprognostic (2.27e-1)" "unprognostic (2.03e-1)" "unprognostic (1.92e-2)" "unprognostic (2.99e-3)" "potential prognostic unfavorable (4.41e-4)" "unprognostic (1.53e-2)" "unprognostic (4.51e-2)" "unprognostic (1.45e-1)" "unprognostic (2.78e-2)" "unprognostic (6.43e-2)" "unprognostic (1.63e-1)" "unprognostic (8.91e-2)" "unprognostic (1.71e-2)" ATAD5 "C17orf41, ELG1, FLJ12735, FRAG1" ENSG00000176208 "ATPase family AAA domain containing 5" Q96QE3 17 30831966-30895869 "Essential proteins, Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 105.2;Epicardial cells: 129.6;Erythrocyte progenitors: 322.5;Megakaryocyte progenitors: 119.7;Monocyte progenitors: 155.8;Neutrophil progenitors: 97.8" "Cell type enhanced" "Detected in all" "Erythrocytes: 322.5;Mononuclear phagocytes: 155.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2088 "Granulosa cells: 208757.4" "Not detected" "Not detected" HPA066823 Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 12 Nucleoplasm "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA066823: " "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (5.94e-2)" "unprognostic (1.76e-2)" "unprognostic (1.64e-1)" "unprognostic (2.43e-1)" "unprognostic (3.66e-1)" "unprognostic (6.58e-3)" "unprognostic (1.12e-2)" "unprognostic (8.28e-2)" "unprognostic (1.30e-3)" "unprognostic (1.25e-2)" "unprognostic (4.42e-3)" "unprognostic (2.24e-1)" "unprognostic (8.15e-3)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (5.38e-4)" "unprognostic (1.78e-3)" "unprognostic (1.58e-2)" "unprognostic (4.25e-3)" "unprognostic (2.10e-2)" "unprognostic (3.38e-1)" "unprognostic (7.33e-3)" ATAT1 "C6orf134, Em:AB023049.7, FLJ13158, MEC17" ENSG00000137343 "Alpha tubulin acetyltransferase 1" Q5SQI0 6 30626842-30646823 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.4" "Cell type enhanced" "Detected in many" "Astrocytes: 24.1;Bergmann glia: 22.2;Brain inhibitory neurons: 15.7;Choroid plexus epithelial cells: 16.0;Distal convoluted tubule cells: 16.7;Early spermatids: 48.1;Ependymal cells: 25.9;Late primary spermatocytes: 17.7;Late spermatids: 42.0;Loop of henle epithelial cells: 17.6;Oligodendrocyte progenitor cells: 28.3;Oligodendrocytes: 22.2;Other brain neurons: 17.8;Papillary tip epithelial cells: 15.1;Proximal tubule cells: 19.7;Renal collecting duct intercalated cells: 16.6;Renal collecting duct principal cells: 16.2;Renal connecting tubule cells: 20.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 25.9;Ductal cells: 20.1;Glial cells: 28.3;Neuronal cells: 17.8;Renal nephron cells: 19.7;Spermatogenic cell types: 48.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 5302464.1;Microglia and Neuropil: 3900716.5" "Group enriched" "Detected in some" "cerebral cortex: 14351235.0;ovary: 9642505.3" "HPA046816, HPA050999" Approved Supported "Golgi apparatus,Cytosol" "Intracellular and membrane" Enzyme No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 4 Cytosol "Golgi apparatus" "HPA046816: , HPA050999: " "unprognostic (1.17e-1)" "unprognostic (6.37e-2)" "unprognostic (2.75e-1)" "unprognostic (5.12e-2)" "unprognostic (1.85e-1)" "unprognostic (1.82e-1)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (1.25e-2)" "unprognostic (3.19e-1)" "unprognostic (3.76e-2)" "unprognostic (2.11e-1)" "unprognostic (1.09e-2)" "unprognostic (3.89e-1)" "unprognostic (1.96e-1)" "unprognostic (2.43e-1)" "unprognostic (6.89e-3)" "unprognostic (1.15e-1)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" ATF1 TREB36 ENSG00000123268 "Activating transcription factor 1" P18846 12 50763710-50821162 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enhanced" "Detected in some" "ovary: 36303.3" "CAB016222, HPA055069, HPA055406" Supported Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 38: Non-specific - Transcription" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 9 Nucleoplasm "CAB016222: , HPA055069: , HPA055406: " "unprognostic (6.90e-2)" "unprognostic (1.03e-2)" "unprognostic (6.69e-2)" "unprognostic (6.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (9.66e-2)" "unprognostic (2.98e-1)" "unprognostic (2.24e-1)" "unprognostic (7.07e-2)" "potential prognostic favorable (8.34e-6)" "unprognostic (4.04e-2)" "unprognostic (9.13e-2)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (2.57e-2)" "unprognostic (4.58e-2)" "unprognostic (7.05e-2)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (1.76e-1)" "unprognostic (8.02e-2)" "unprognostic (2.20e-3)" "unprognostic (3.27e-2)" "unprognostic (1.31e-2)" "unprognostic (1.80e-2)" "unprognostic (9.65e-2)" "unprognostic (1.43e-1)" "unprognostic (6.41e-2)" "unprognostic (2.58e-1)" "unprognostic (9.35e-2)" "unprognostic (1.56e-1)" ATF3 ENSG00000162772 "Activating transcription factor 3" P18847 1 212565334-212620777 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 1394.6;Endometrial glandular cells: 1349.7;Endometrial luminal cells: 1837.3;Epididymal basal cells: 1805.0;Epididymal efferent duct absorptive cells: 1270.5;Fallopian secretory cells: 1313.3;Smooth muscle cells: 1236.3" "Cell type enhanced" "Detected in all" "Basal cells: 1805.0;Luminal cells: 1837.3" "Group enriched" "Detected in all" 6 "endothelial cell: 116.3;ependymal cell: 62.0;vascular associated smooth muscle cell: 213.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.5;non-classical monocyte: 6.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 13.2" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 292078 "intestine: 29207766.5" HPA001562 Approved Supported "Nucleoplasm,Nucleoli,Vesicles,Centrosome,Basal body" Yes Yes "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 52 "Nucleoplasm, Nucleoli, Basal body" "Vesicles, Centrosome" "HPA001562: " "unprognostic (6.77e-2)" "unprognostic (5.03e-2)" "unprognostic (3.92e-2)" "unprognostic (1.13e-1)" "unprognostic (2.61e-2)" "unprognostic (2.03e-1)" "unprognostic (9.19e-2)" "unprognostic (8.15e-2)" "unprognostic (9.02e-2)" "unprognostic (1.62e-1)" "unprognostic (1.26e-2)" "unprognostic (8.11e-3)" "unprognostic (2.23e-1)" "unprognostic (1.74e-1)" "unprognostic (5.19e-2)" "unprognostic (2.88e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (6.51e-3)" "unprognostic (1.31e-1)" "unprognostic (2.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.11e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (4.33e-5)" "unprognostic (2.30e-2)" "unprognostic (3.02e-2)" "unprognostic (1.65e-1)" "unprognostic (1.32e-2)" "unprognostic (2.80e-1)" ATF4 "CREB-2, TAXREB67, TXREB" ENSG00000128272 "Activating transcription factor 4" P18848 22 39519695-39522683 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 615.2;Esophageal apical cells: 599.5;Platelets: 502.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011596, HPA062987" Approved Supported Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 15: Non-specific - Protein processing" 77 Nucleoplasm "CAB011596: , HPA062987: " "unprognostic (1.15e-1)" "unprognostic (6.21e-2)" "unprognostic (2.44e-1)" "unprognostic (3.28e-2)" "unprognostic (4.40e-2)" "unprognostic (2.32e-2)" "unprognostic (3.91e-2)" "unprognostic (1.24e-1)" "unprognostic (7.17e-3)" "unprognostic (4.35e-2)" "unprognostic (4.05e-2)" "unprognostic (9.74e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (9.32e-3)" "unprognostic (2.30e-1)" "unprognostic (9.31e-2)" "unprognostic (1.64e-2)" "unprognostic (4.32e-2)" "unprognostic (2.01e-2)" "unprognostic (9.21e-2)" "unprognostic (3.05e-1)" "unprognostic (1.55e-1)" "unprognostic (2.53e-1)" "unprognostic (2.22e-2)" "unprognostic (3.01e-2)" "unprognostic (5.96e-2)" "unprognostic (5.87e-2)" "unprognostic (6.27e-2)" "unprognostic (6.06e-2)" "unprognostic (4.62e-1)" ATF6 ATF6A ENSG00000118217 "Activating transcription factor 6" P18850 1 161766298-161977574 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 903.8" "Cell type enhanced" "Detected in all" "Neutrophils: 903.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Pancreatic islets: 1857275.4" "Not detected" "Not detected" "HPA005935, HPA071169" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Endoplasmic reticulum,Golgi apparatus,Primary cilium,Primary cilium tip,Cytosol" NA NA 4800000 "Cluster 28: Neutrophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 19 "Nucleoplasm, Golgi apparatus" "Nucleoli, Nucleoli fibrillar center, Endoplasmic reticulum, Primary cilium, Primary cilium tip, Cytosol" "HPA005935: , HPA071169: " "unprognostic (9.93e-2)" "unprognostic (1.18e-2)" "unprognostic (6.50e-3)" "unprognostic (1.27e-3)" "unprognostic (1.46e-1)" "unprognostic (9.01e-2)" "unprognostic (2.34e-2)" "unprognostic (2.72e-1)" "unprognostic (3.52e-3)" "unprognostic (6.34e-3)" "potential prognostic favorable (9.62e-5)" "unprognostic (2.07e-1)" "unprognostic (3.43e-2)" "unprognostic (1.07e-1)" "unprognostic (1.17e-1)" "unprognostic (3.62e-2)" "unprognostic (7.31e-3)" "unprognostic (7.07e-2)" "unprognostic (4.65e-1)" "unprognostic (1.34e-1)" "unprognostic (3.12e-3)" "unprognostic (3.36e-2)" "unprognostic (4.01e-1)" "unprognostic (1.09e-1)" "unprognostic (8.06e-2)" "unprognostic (9.14e-3)" "unprognostic (9.17e-2)" "unprognostic (1.43e-1)" "unprognostic (1.91e-1)" "unprognostic (3.92e-3)" "unprognostic (1.87e-1)" ATG12 "APG12, APG12L" ENSG00000145782 "Autophagy related 12" O94817 5 115828200-115841837 "Predicted intracellular proteins, Transporters" "Autophagy, Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" "fallopian tube: 953431.8;lymphoid tissue: 821443.3" "CAB013272, HPA068989" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 42 "Nucleoplasm, Vesicles" "CAB013272: , HPA068989: " "unprognostic (8.64e-2)" "unprognostic (2.23e-3)" "unprognostic (2.96e-1)" "unprognostic (1.61e-1)" "unprognostic (6.95e-2)" "unprognostic (1.86e-2)" "unprognostic (1.57e-1)" "unprognostic (6.40e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (7.17e-4)" "unprognostic (1.27e-2)" "unprognostic (3.16e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (1.56e-5)" "unprognostic (1.62e-1)" "unprognostic (4.59e-3)" "unprognostic (3.89e-2)" "unprognostic (5.19e-2)" "unprognostic (1.54e-1)" "unprognostic (9.32e-2)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (7.56e-2)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.29e-1)" "unprognostic (6.46e-2)" "unprognostic (8.43e-3)" "unprognostic (2.34e-2)" "unprognostic (1.86e-1)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (1.81e-4)" "unprognostic (2.34e-1)" ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 213.6;Extravillous trophoblasts: 198.7;Migrating cytotrophoblasts: 238.8" "Cell type enhanced" "Detected in all" "Trophoblast cells: 238.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 4900000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 8 Cytosol "Plasma membrane" "CAB013462: , HPA021012: " "unprognostic (1.03e-1)" "unprognostic (2.48e-3)" "unprognostic (1.03e-2)" "unprognostic (2.29e-1)" "unprognostic (1.05e-1)" "unprognostic (1.68e-1)" "unprognostic (1.25e-1)" "unprognostic (3.71e-2)" "unprognostic (2.21e-2)" "unprognostic (1.45e-1)" "unprognostic (7.94e-3)" "unprognostic (1.53e-1)" "unprognostic (1.48e-3)" "validated prognostic unfavorable (1.07e-8)" "validated prognostic unfavorable (1.55e-8)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (2.74e-3)" "unprognostic (2.35e-1)" "unprognostic (3.67e-1)" "unprognostic (9.19e-2)" "unprognostic (7.04e-2)" "unprognostic (2.95e-3)" "unprognostic (1.32e-1)" "unprognostic (2.09e-3)" "unprognostic (6.19e-3)" "unprognostic (4.06e-2)" "unprognostic (2.84e-2)" "unprognostic (5.04e-2)" "unprognostic (3.82e-1)" "unprognostic (1.74e-2)" "unprognostic (2.80e-1)" ATM "ATA, ATC, ATD, ATDC, TEL1, TELO1" ENSG00000149311 "ATM serine/threonine kinase" Q13315 11 108223044-108369102 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 697.0;NK-cells: 485.7" "Cell type enhanced" "Detected in many" "Glial cells: 697.0" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 888.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 24905579.7;T-cells: 47695645.5" "Tissue enriched" "Detected in many" "lymphoid tissue: 24393148.1" "CAB000102, HPA067142, CAB080442" Supported Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 135 "Nucleoplasm, Vesicles" "Golgi apparatus" "CAB000102: , CAB080442: , HPA067142: " "unprognostic (2.69e-1)" "unprognostic (6.32e-2)" "unprognostic (1.94e-2)" "unprognostic (9.50e-2)" "unprognostic (1.70e-2)" "unprognostic (2.85e-1)" "unprognostic (1.03e-1)" "unprognostic (1.12e-2)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (8.17e-2)" "unprognostic (1.58e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-3)" "unprognostic (3.25e-1)" "unprognostic (1.53e-1)" "unprognostic (1.11e-2)" "unprognostic (1.86e-1)" "unprognostic (2.19e-1)" "unprognostic (2.65e-1)" "unprognostic (9.19e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (2.44e-2)" "potential prognostic favorable (7.18e-4)" "unprognostic (3.20e-3)" "unprognostic (4.43e-2)" "unprognostic (2.30e-1)" "unprognostic (3.00e-1)" "unprognostic (1.18e-1)" "unprognostic (1.31e-1)" ATMIN "ASCIZ, KIAA0431, ZNF822" ENSG00000166454 "ATM interactor" O43313 16 81035842-81047350 "Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 225.0;Late spermatids: 438.1" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 438.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054967, HPA066900" Approved Supported "Nuclear bodies" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 11 "Nuclear bodies" "HPA054967: , HPA066900: " "unprognostic (1.71e-2)" "unprognostic (5.63e-2)" "unprognostic (6.20e-2)" "unprognostic (9.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.27e-2)" "unprognostic (1.24e-1)" "unprognostic (1.27e-2)" "unprognostic (1.48e-2)" "unprognostic (2.43e-2)" "potential prognostic favorable (1.12e-5)" "unprognostic (5.95e-2)" "unprognostic (5.26e-2)" "unprognostic (1.66e-2)" "unprognostic (7.87e-2)" "unprognostic (6.49e-2)" "unprognostic (3.96e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (4.29e-2)" "unprognostic (7.49e-3)" "unprognostic (1.88e-1)" "unprognostic (2.78e-2)" "unprognostic (5.57e-2)" "unprognostic (4.10e-2)" "unprognostic (2.89e-3)" "unprognostic (1.20e-1)" "unprognostic (2.18e-1)" "unprognostic (4.14e-1)" "unprognostic (3.16e-1)" "unprognostic (2.09e-2)" ATOH7 "bHLHa13, Math5" ENSG00000179774 "Atonal bHLH transcription factor 7" Q8N100 10 68230595-68232113 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.0;kidney: 1.2;liver: 2.9" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 3.1;Brain inhibitory neurons: 1.2;Epididymal principal cells: 1.2;Granulosa cells: 1.6;Hepatocytes: 1.6;Other brain neurons: 1.2;Undifferentiated spermatogonia: 2.1" "Cell type enhanced" "Detected in some" "Hepatocytes: 1.6;Neuronal cells: 3.1;Reproductive supporting cells: 1.6;Spermatogenic cell types: 2.1" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 17.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.0" "Kidney - Proximal tubular cells" "Region enriched" "Detected in some" 9 "cerebellum: 28.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA027008 Uncertain Supported "Nucleoplasm,Cytosol,Flagellar centriole,Mid piece" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nucleoplasm, Flagellar centriole" "Cytosol, Mid piece" "HPA027008: " ATP11A "ATPIH, ATPIS, KIAA1021" ENSG00000068650 "ATPase phospholipid transporting 11A" P98196 13 112690038-112887168 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Deafness, Disease variant, Leukodystrophy, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 870.3;Alveolar cells type 2: 1064.8;Cone photoreceptor cells: 573.4;Endometrial glandular cells: 1767.9;Endometrial luminal cells: 1206.9;Neutrophils: 682.4;Somatotrophs: 1156.7;Transitional alveolar cells: 712.8" "Cell type enhanced" "Detected in all" "Alveolar cells: 1064.8;Glandular cells: 1767.9;Luminal cells: 1206.9;Pituitary endocrine cells: 1156.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 7725059.1;Neutrophils: 4688995.8;Proximal tubules: 4804622.9" "Tissue enhanced" "Detected in many" "lung: 3875129.1" "HPA035583, HPA035584" Approved Supported "Golgi apparatus,Vesicles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 35: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 51: Secretory epithelial cells - Mixed function" 8 Vesicles "Golgi apparatus" "HPA035583: , HPA035584: " "unprognostic (4.62e-2)" "unprognostic (3.28e-1)" "unprognostic (5.24e-2)" "unprognostic (2.06e-3)" "unprognostic (9.70e-2)" "unprognostic (6.96e-3)" "unprognostic (8.90e-2)" "unprognostic (3.61e-2)" "unprognostic (7.27e-2)" "unprognostic (2.41e-1)" "validated prognostic favorable (1.81e-10)" "validated prognostic favorable (1.22e-4)" "unprognostic (5.19e-2)" "unprognostic (4.39e-3)" "unprognostic (4.81e-3)" "unprognostic (3.11e-2)" "unprognostic (3.26e-1)" "potential prognostic unfavorable (8.46e-6)" "unprognostic (3.67e-1)" "unprognostic (1.30e-3)" "unprognostic (1.62e-1)" "unprognostic (1.80e-2)" "unprognostic (3.40e-3)" "unprognostic (4.41e-1)" "unprognostic (3.25e-1)" "unprognostic (3.30e-2)" "unprognostic (7.57e-3)" "unprognostic (4.35e-2)" "unprognostic (1.93e-1)" "unprognostic (1.49e-1)" "unprognostic (1.24e-1)" ATP2A2 "ATP2B, DAR, SERCA2" ENSG00000174437 "ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2" P16615 12 110280756-110351093 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "heart muscle: 941.9;skeletal muscle: 2675.7;tongue: 2586.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1387.6;Endometrial ciliated cells: 881.0;Myonuclei: 3843.3" "Cell type enriched" "Detected in all" 4 "Myocytes: 3843.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Cardiomyocytes: 928858561.1;Skeletal myofibers: 3019434630.4" "Group enriched" "Detected in all" "heart muscle: 418196704.3;skeletal muscle: 1581592681.4" HPA062605 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Primary cilium,Perinuclear theca,Mid piece,End piece" NA NA 2900000 "Cluster 33: Non-specific - ATP binding" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 48 "Nucleoplasm, Plasma membrane" "Primary cilium, Perinuclear theca, Mid piece, End piece" "HPA062605: " "unprognostic (2.11e-2)" "unprognostic (5.36e-2)" "unprognostic (4.68e-2)" "unprognostic (2.69e-3)" "unprognostic (2.12e-2)" "unprognostic (4.21e-1)" "unprognostic (4.64e-1)" "unprognostic (1.79e-1)" "unprognostic (4.40e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.94e-5)" "unprognostic (1.95e-3)" "unprognostic (1.64e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-2)" "unprognostic (2.30e-1)" "unprognostic (8.97e-2)" "unprognostic (2.72e-2)" "unprognostic (2.24e-1)" "unprognostic (4.04e-2)" "unprognostic (6.81e-3)" "unprognostic (3.32e-3)" "unprognostic (1.92e-1)" "unprognostic (2.88e-1)" "unprognostic (1.16e-1)" "unprognostic (9.84e-3)" "unprognostic (1.27e-1)" "unprognostic (1.97e-1)" "unprognostic (7.70e-2)" "unprognostic (6.33e-2)" "unprognostic (1.96e-1)" ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626832-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 164.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 486.4;Basal keratinocytes: 496.5;Smooth muscle cells: 476.1;Suprabasal keratinocytes: 691.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "testis cancer: 204.8" "Prostate - Smooth muscle cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 107847954.2;Microglia and Neuropil: 140635857.4" "Tissue enhanced" "Detected in all" "cerebral cortex: 200355169.9;skeletal muscle: 193761421.9" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane,Primary cilium,Mitochondria,Basal body" NA NA 58000 "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 26: Keratinocytes - Keratinization" 19 "Plasma membrane, Primary cilium" "Mitochondria, Basal body" "CAB016118: , HPA040431: " "unprognostic (3.94e-2)" "unprognostic (2.47e-1)" "unprognostic (1.57e-1)" "unprognostic (2.30e-2)" "unprognostic (3.38e-1)" "unprognostic (1.10e-1)" "unprognostic (1.31e-1)" "unprognostic (2.92e-1)" "unprognostic (1.35e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (2.76e-5)" "unprognostic (3.87e-2)" "unprognostic (4.62e-2)" "unprognostic (5.16e-2)" "unprognostic (1.95e-1)" "unprognostic (2.91e-1)" "unprognostic (6.45e-2)" "unprognostic (2.55e-2)" "unprognostic (3.33e-1)" "unprognostic (4.89e-2)" "unprognostic (3.97e-2)" "unprognostic (3.61e-2)" "unprognostic (1.38e-1)" "unprognostic (1.01e-1)" "unprognostic (7.18e-2)" "unprognostic (1.78e-2)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.94e-1)" "unprognostic (4.82e-2)" "unprognostic (1.37e-1)" ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.1;salivary gland: 19.1;skin 1: 24.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 411.4;Colonocytes: 152.0;Endometrial glandular cells: 248.4;Enteric stem cells: 211.5;Enteric transient amplifying cells: 193.8;Goblet cells: 228.0;Oligodendrocyte progenitor cells: 194.0;Paneth cells: 127.6;Prostatic glandular cells: 131.9;Respiratory basal cells: 157.9;Respiratory ciliated cells: 189.0;Respiratory deuterosomal cells: 213.5;Respiratory secretory cells: 209.7" "Cell type enhanced" "Detected in many" "Glandular cells: 248.4;Secretory cells: 411.4" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 170.4;oligodendrocyte precursor cell: 224.5" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 33.0;Rectum Adenocarcinoma (TCGA): 31.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Alveolar cell types: 69978.1" "Tissue enriched" "Detected in single" 905 "salivary gland: 90470.9" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 77: Intestine - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "Plasma membrane, Focal adhesion sites" "HPA052262: , HPA075812: " "unprognostic (5.22e-2)" "unprognostic (2.33e-2)" "unprognostic (1.94e-1)" "unprognostic (1.71e-1)" "unprognostic (1.76e-2)" "unprognostic (9.94e-2)" "unprognostic (2.13e-2)" "unprognostic (3.55e-1)" "unprognostic (3.05e-2)" "unprognostic (1.14e-1)" "unprognostic (2.47e-1)" "unprognostic (3.39e-3)" "unprognostic (4.37e-1)" "unprognostic (4.96e-2)" "unprognostic (5.58e-2)" "unprognostic (3.10e-2)" "unprognostic (6.33e-1)" "unprognostic (7.39e-2)" "unprognostic (2.44e-3)" "unprognostic (1.38e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-3)" "unprognostic (4.20e-2)" ATP5F1A "ATP5A, ATP5A1, ATP5AL2, ATPM, hATP1, OMR, ORM" ENSG00000152234 "ATP synthase F1 subunit alpha" P25705 18 46080248-46104334 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1644.4" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 909.5;Esophageal basal cells: 785.0;Esophageal suprabasal cells: 839.8;Migrating cytotrophoblasts: 803.6;Parietal cells: 912.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 10232616373.0" "Tissue enhanced" "Detected in all" "heart muscle: 5386567814.7" "CAB013067, HPA040622, HPA044202" Enhanced Supported "Mitochondria,End piece" NA NA 10000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 97: Non-specific - Cellular respiration" 101 Mitochondria "End piece" "CAB013067: , HPA040622: , HPA044202: " "unprognostic (6.94e-2)" "unprognostic (1.33e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (6.03e-4)" "unprognostic (2.61e-1)" "unprognostic (3.51e-2)" "potential prognostic favorable (7.64e-4)" "unprognostic (2.37e-1)" "unprognostic (2.50e-2)" "potential prognostic favorable (1.15e-9)" "unprognostic (2.70e-3)" "potential prognostic favorable (9.27e-6)" "unprognostic (3.87e-2)" "unprognostic (1.82e-1)" "unprognostic (2.07e-3)" "unprognostic (1.18e-1)" "unprognostic (1.42e-2)" "unprognostic (1.43e-1)" "unprognostic (1.78e-1)" "unprognostic (1.26e-2)" "unprognostic (1.11e-1)" "unprognostic (5.44e-2)" "unprognostic (7.21e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-1)" "unprognostic (5.19e-2)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" ATP5F1B "ATP5B, ATPSB" ENSG00000110955 "ATP synthase F1 subunit beta" P06576 12 56638175-56645984 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2427.2;tongue: 2993.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 974.9;Esophageal basal cells: 1127.5;Esophageal suprabasal cells: 1098.0;Parietal cells: 1278.2;Syncytiotrophoblasts: 1350.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 7258386192.5" "Tissue enriched" "Detected in all" "heart muscle: 7407252153.4" "HPA001520, HPA001528, CAB017527" Enhanced Enhanced Mitochondria NA NA 22000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 116 Mitochondria "CAB017527: , HPA001520: , HPA001528: " "unprognostic (5.81e-3)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (7.14e-2)" "unprognostic (2.12e-3)" "unprognostic (4.71e-2)" "unprognostic (3.79e-1)" "unprognostic (1.10e-1)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (6.64e-4)" "potential prognostic favorable (6.35e-8)" "unprognostic (4.50e-2)" "unprognostic (5.93e-3)" "unprognostic (4.63e-3)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (4.07e-3)" "unprognostic (1.82e-1)" "unprognostic (4.90e-1)" "unprognostic (2.95e-1)" "unprognostic (4.25e-2)" "unprognostic (5.38e-1)" "unprognostic (2.67e-2)" "unprognostic (3.85e-2)" "unprognostic (5.37e-2)" "unprognostic (4.05e-1)" "unprognostic (2.50e-2)" "unprognostic (1.09e-1)" "unprognostic (2.95e-1)" "unprognostic (7.78e-2)" "unprognostic (3.97e-2)" ATP5ME ATP5I ENSG00000169020 "ATP synthase membrane subunit e" P56385 4 672436-674330 "Metabolic proteins, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 1506.0;Enterocytes: 2035.5;Hepatocytes: 3036.6;Parietal cells: 4661.9" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 4661.9;Hepatocytes: 3036.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 52387250.5" "Tissue enhanced" "Detected in all" "heart muscle: 236789584.8" HPA035010 Enhanced Supported Mitochondria NA NA 140000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 22 Mitochondria "HPA035010: " "unprognostic (4.36e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (3.66e-4)" "unprognostic (2.78e-2)" "potential prognostic favorable (1.93e-4)" "unprognostic (2.13e-2)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (6.96e-5)" "unprognostic (3.86e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-2)" "unprognostic (7.60e-3)" "unprognostic (1.08e-1)" "unprognostic (4.04e-2)" "unprognostic (7.15e-2)" "unprognostic (9.93e-2)" "unprognostic (3.68e-2)" "unprognostic (5.41e-3)" "unprognostic (2.05e-2)" "unprognostic (4.55e-2)" "unprognostic (1.86e-1)" "unprognostic (7.72e-2)" "unprognostic (7.17e-2)" "unprognostic (8.80e-3)" "unprognostic (4.36e-2)" "unprognostic (3.17e-2)" "unprognostic (2.66e-1)" "unprognostic (1.46e-1)" "unprognostic (2.68e-1)" ATP5MG "ATP5JG, ATP5L" ENSG00000167283 "ATP synthase membrane subunit g" O75964 11 118401346-118433278 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 2796.8" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 2796.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 275490479.6;Distal tubules: 316883025.6" "Tissue enhanced" "Detected in all" "heart muscle: 87818982.4" HPA044629 Approved Supported "Mitochondria,Principal piece" NA NA 130000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "Principal piece" "HPA044629: " "unprognostic (2.45e-1)" "unprognostic (1.69e-1)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (5.26e-3)" "unprognostic (2.29e-1)" "unprognostic (2.17e-1)" "unprognostic (8.84e-2)" "unprognostic (2.33e-3)" "unprognostic (6.24e-3)" "unprognostic (1.84e-1)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (4.83e-5)" "unprognostic (9.52e-3)" "unprognostic (2.25e-1)" "unprognostic (8.58e-2)" "unprognostic (1.47e-1)" "unprognostic (4.68e-2)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.59e-1)" "unprognostic (5.23e-2)" "unprognostic (2.09e-1)" "unprognostic (7.65e-2)" "unprognostic (2.16e-3)" "unprognostic (6.94e-2)" "unprognostic (1.78e-1)" "unprognostic (1.32e-1)" "unprognostic (5.63e-2)" ATP5MGL "ATP5K2, ATP5L2, dJ222E13.5" ENSG00000249222 "ATP synthase membrane subunit g like" Q7Z4Y8 22 42639803-42640601 "Metabolic proteins, Predicted membrane proteins" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA044629 Uncertain Approved "Mitochondria,Principal piece" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" Mitochondria "Principal piece" "HPA044629: " "unprognostic (2.04e-3)" "unprognostic (1.18e-2)" "unprognostic (2.19e-3)" "unprognostic (6.80e-3)" ATP5PB ATP5F1 ENSG00000116459 "ATP synthase peripheral stalk-membrane subunit b" P24539 1 111448864-111462773 "Essential proteins, Metabolic proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 127.5;tongue: 122.9" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 586.0;Late primary spermatocytes: 583.9;Parietal cells: 899.9" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 899.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 989612171.5" "Tissue enhanced" "Detected in all" "heart muscle: 317753070.5" "HPA046067, HPA057347" Enhanced Supported Mitochondria NA NA 91000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 113 Mitochondria "HPA046067: , HPA057347: " "unprognostic (2.73e-1)" "unprognostic (5.29e-2)" "unprognostic (1.11e-2)" "unprognostic (3.19e-3)" "unprognostic (1.33e-1)" "unprognostic (1.74e-1)" "unprognostic (2.76e-1)" "unprognostic (5.02e-2)" "potential prognostic unfavorable (5.58e-4)" "validated prognostic favorable (3.65e-13)" "validated prognostic favorable (5.29e-5)" "unprognostic (2.22e-1)" "unprognostic (1.63e-1)" "unprognostic (1.22e-1)" "unprognostic (2.68e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.69e-1)" "unprognostic (2.26e-1)" "unprognostic (5.62e-2)" "unprognostic (4.89e-1)" "unprognostic (6.19e-2)" "unprognostic (1.95e-3)" "unprognostic (1.05e-1)" "unprognostic (1.17e-2)" "unprognostic (8.96e-2)" "unprognostic (8.26e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" ATP5PF "ATP5, ATP5A, ATP5J, ATPM, CF6" ENSG00000154723 "ATP synthase peripheral stalk subunit F6" P18859 21 25716503-25735673 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1487.1" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 1306.6;Hepatocytes: 1869.1;Parietal cells: 2635.9" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 2635.9;Hepatocytes: 1869.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 125063410.3" "Tissue enriched" "Detected in all" "heart muscle: 1322109925.0" HPA031069 Supported Supported "Mitochondria,Flagellar centriole,End piece" NA NA 240000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 97: Non-specific - Cellular respiration" 81 Mitochondria "Flagellar centriole, End piece" "HPA031069: " "unprognostic (1.31e-1)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (6.96e-3)" "unprognostic (1.39e-1)" "unprognostic (2.18e-1)" "unprognostic (1.35e-1)" "unprognostic (3.70e-2)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (2.41e-1)" "potential prognostic favorable (1.01e-6)" "unprognostic (1.43e-1)" "unprognostic (4.85e-2)" "unprognostic (2.40e-1)" "unprognostic (1.42e-3)" "unprognostic (8.45e-2)" "unprognostic (2.36e-1)" "unprognostic (1.09e-1)" "unprognostic (9.66e-2)" "unprognostic (3.75e-1)" "unprognostic (1.02e-1)" "unprognostic (2.46e-1)" "unprognostic (3.31e-1)" "unprognostic (3.18e-2)" "unprognostic (3.47e-2)" "unprognostic (1.51e-1)" "unprognostic (6.88e-2)" "unprognostic (1.77e-1)" "unprognostic (4.50e-1)" "unprognostic (2.04e-1)" ATP5PO "ATP5O, ATPO, OSCP" ENSG00000241837 "ATP synthase peripheral stalk subunit OSCP" P48047 21 33903453-33915814 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "ATP synthesis, Hydrogen ion transport, Ion transport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 1494.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 770.7;Esophageal basal cells: 774.3;Esophageal suprabasal cells: 989.4;Late primary spermatocytes: 769.1;Parietal cells: 1591.1" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 1591.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 936814381.0" "Tissue enhanced" "Detected in all" "heart muscle: 633474859.1" "CAB016209, HPA041394" Enhanced Approved Mitochondria NA NA 110000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 47: Leukemia - Hemostasis" "Cluster 97: Non-specific - Cellular respiration" 72 Mitochondria "CAB016209: , HPA041394: " "unprognostic (1.43e-1)" "unprognostic (4.15e-3)" "unprognostic (1.67e-2)" "unprognostic (1.44e-1)" "unprognostic (5.03e-2)" "unprognostic (1.04e-1)" "unprognostic (2.16e-1)" "unprognostic (3.06e-2)" "unprognostic (4.36e-2)" "potential prognostic favorable (1.51e-4)" "unprognostic (4.84e-2)" "potential prognostic favorable (3.73e-4)" "unprognostic (7.51e-2)" "unprognostic (4.75e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (3.56e-1)" "unprognostic (2.48e-1)" "unprognostic (4.67e-1)" "unprognostic (1.83e-1)" "unprognostic (8.47e-2)" "unprognostic (1.77e-1)" "unprognostic (9.20e-2)" "unprognostic (3.04e-2)" "unprognostic (5.03e-3)" "unprognostic (2.03e-2)" "unprognostic (9.92e-2)" "unprognostic (4.53e-2)" "unprognostic (2.14e-2)" ATP6V0A1 "a1, ATP6N1, ATP6N1A, Stv1, Vph1, VPP1" ENSG00000033627 "ATPase H+ transporting V0 subunit a1" Q93050 17 42458844-42522582 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 98.9" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 409.9" "Cell type enhanced" "Detected in all" "Neuronal cells: 409.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 294569541.7;Microglia and Neuropil: 517037843.3" "Tissue enriched" "Detected in all" "cerebral cortex: 414367543.0" HPA022144 Enhanced Approved "Nuclear speckles,Golgi apparatus,Vesicles,Cytosol" NA NA 6500 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 79: Photoreceptor cells - Phototransduction" 53 "Golgi apparatus, Vesicles" "Nuclear speckles, Cytosol" "HPA022144: " "unprognostic (1.06e-1)" "unprognostic (9.02e-3)" "unprognostic (2.36e-2)" "unprognostic (7.27e-3)" "unprognostic (5.14e-2)" "unprognostic (4.57e-2)" "unprognostic (1.52e-1)" "unprognostic (1.84e-2)" "unprognostic (8.46e-2)" "unprognostic (3.15e-2)" "potential prognostic favorable (9.79e-8)" "unprognostic (8.12e-3)" "unprognostic (1.91e-1)" "unprognostic (9.55e-2)" "unprognostic (1.80e-2)" "unprognostic (8.57e-2)" "unprognostic (8.14e-2)" "unprognostic (2.47e-2)" "unprognostic (1.08e-1)" "unprognostic (3.07e-2)" "unprognostic (6.82e-2)" "unprognostic (1.67e-3)" "unprognostic (5.98e-2)" "unprognostic (1.17e-1)" "unprognostic (3.52e-3)" "unprognostic (5.15e-3)" "unprognostic (3.08e-1)" "unprognostic (4.18e-1)" "unprognostic (2.04e-1)" "unprognostic (6.16e-2)" "unprognostic (8.55e-3)" ATP6V1A "ATP6A1, ATP6V1A1, VA68, Vma1, VPP2" ENSG00000114573 "ATPase H+ transporting V1 subunit A" P38606 3 113746770-113812056 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" Translocase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 758.7;Epididymal clear cells: 516.5;Late spermatids: 1351.5;Neutrophils: 680.2;Renal collecting duct intercalated cells: 463.0;Respiratory ionocytes: 612.2;Salivary ionocytes: 487.5" "Cell type enhanced" "Detected in all" "Ionocytes: 612.2;Neutrophils: 680.2;Spermatogenic cell types: 1351.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 228.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 78.5" "Group enriched" "Detected in all" 6 "dendritic cells: 36.2;granulocytes: 78.5;monocytes: 34.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in all" "cerebral cortex: 671279924.8" "CAB006910, HPA035084" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA 1000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 36: Brain & Liver - Signaling" "Cluster 24: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 62 "Vesicles, Cytosol" Nucleoplasm "CAB006910: , HPA035084: " "unprognostic (1.53e-1)" "unprognostic (8.63e-2)" "unprognostic (2.41e-3)" "unprognostic (2.31e-1)" "unprognostic (1.72e-2)" "unprognostic (1.49e-2)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.43e-3)" "potential prognostic favorable (3.52e-10)" "unprognostic (1.26e-1)" "unprognostic (7.06e-2)" "unprognostic (3.94e-2)" "unprognostic (2.67e-2)" "unprognostic (2.32e-1)" "unprognostic (1.60e-1)" "unprognostic (3.77e-2)" "unprognostic (1.17e-1)" "unprognostic (1.59e-1)" "unprognostic (4.48e-3)" "unprognostic (8.21e-3)" "unprognostic (1.70e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.77e-1)" "unprognostic (8.44e-2)" "unprognostic (3.35e-1)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.67e-1)" ATP6V1B1 "ATP6B1, RTA1B, VATB, Vma2, VPP3" ENSG00000116039 "ATPase H+ transporting V1 subunit B1" P15313 2 70935900-70965431 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 128.7;salivary gland: 131.8" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 65.0;Cytotrophoblasts: 42.2;Epididymal clear cells: 167.4;Fallopian secretory cells: 16.3;Migrating cytotrophoblasts: 24.1;Renal collecting duct intercalated cells: 28.1;Salivary basal cells: 19.1;Salivary duct cells: 87.7;Salivary ionocytes: 44.5" "Group enriched" "Detected in some" 4 "Ductal cells: 87.7;Goblet cells: 65.0;Ionocytes: 44.5;Reproductive supporting cells: 167.4;Trophoblast cells: 42.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 15 "Kidney Chromophobe (TCGA): 522.6;Ovary Serous Cystadenocarcinoma (TCGA): 171.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 14.7;ovarian cancer: 9.8" "Breast - Breast glandular cells (progenitors), Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" "Collecting ducts: 104326264.8;Distal tubules: 228924305.0;Large ducts: 140024513.7" "Group enriched" "Detected in some" "kidney: 3857335.6;salivary gland: 4795543.7" "CAB009523, HPA031847" Enhanced Approved "Nucleoplasm,Nuclear membrane" No NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 43 "Nucleoplasm, Nuclear membrane" "CAB009523: , HPA031847: " "unprognostic (8.00e-2)" "unprognostic (5.16e-2)" "unprognostic (1.62e-1)" "unprognostic (1.55e-1)" "unprognostic (2.26e-1)" "unprognostic (1.02e-1)" "unprognostic (2.77e-2)" "unprognostic (8.48e-2)" "unprognostic (6.98e-2)" "unprognostic (3.67e-2)" "unprognostic (1.59e-1)" "unprognostic (2.00e-1)" "unprognostic (1.90e-2)" "unprognostic (2.03e-2)" "unprognostic (1.39e-1)" "unprognostic (3.78e-1)" "unprognostic (1.18e-1)" "unprognostic (7.56e-3)" "unprognostic (1.58e-2)" "unprognostic (2.07e-1)" "unprognostic (2.76e-2)" "unprognostic (2.76e-2)" "unprognostic (1.62e-1)" "unprognostic (2.94e-1)" ATP6V1G1 "ATP6G, ATP6G1, ATP6GL, ATP6J, DKFZp547P234, Vma10" ENSG00000136888 "ATPase H+ transporting V1 subunit G1" O75348 9 114587706-114598915 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2351.5;Gastric chief cells: 1089.9;Parietal cells: 1295.9;Syncytiotrophoblasts: 1074.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 2351.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubules: 63011931.3" "Tissue enriched" "Detected in all" "kidney: 132504247.4" "CAB004615, HPA042898" Supported Approved Nucleoplasm,Nucleoli NA NA 100000 "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 61 Nucleoli Nucleoplasm "CAB004615: , HPA042898: " "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (8.97e-2)" "unprognostic (5.75e-2)" "unprognostic (1.75e-1)" "unprognostic (2.10e-2)" "unprognostic (2.95e-2)" "unprognostic (1.68e-1)" "unprognostic (1.39e-2)" "unprognostic (7.85e-2)" "potential prognostic favorable (6.20e-9)" "unprognostic (2.53e-2)" "unprognostic (8.46e-2)" "unprognostic (3.93e-2)" "unprognostic (3.77e-2)" "unprognostic (1.38e-1)" "unprognostic (1.72e-1)" "unprognostic (2.72e-1)" "unprognostic (7.14e-2)" "unprognostic (3.37e-1)" "unprognostic (1.34e-1)" "unprognostic (6.04e-2)" "unprognostic (9.14e-2)" "unprognostic (4.67e-2)" "unprognostic (1.97e-1)" "unprognostic (3.57e-1)" "unprognostic (3.43e-1)" "unprognostic (3.17e-1)" "unprognostic (2.78e-1)" "unprognostic (8.41e-2)" "unprognostic (1.20e-3)" ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 619.3" "Cell type enhanced" "Detected in all" "Glandular cells: 619.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia and Neuropil: 142874391.1" "Tissue enriched" "Detected in all" "cerebral cortex: 112342414.8" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 41 "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: , HPA023421: " "unprognostic (1.66e-1)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (1.29e-1)" "unprognostic (1.37e-1)" "unprognostic (3.61e-1)" "unprognostic (2.64e-2)" "unprognostic (6.97e-2)" "unprognostic (2.90e-2)" "unprognostic (5.49e-2)" "unprognostic (4.57e-2)" "potential prognostic favorable (6.52e-6)" "unprognostic (2.24e-1)" "unprognostic (6.67e-2)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (2.78e-2)" "unprognostic (1.67e-1)" "unprognostic (2.87e-1)" "unprognostic (1.05e-1)" "unprognostic (5.68e-3)" "unprognostic (8.45e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (6.94e-2)" "unprognostic (2.49e-1)" "unprognostic (2.96e-1)" "unprognostic (1.15e-1)" "unprognostic (1.92e-1)" "unprognostic (4.39e-2)" "unprognostic (4.00e-1)" "unprognostic (1.09e-1)" "unprognostic (2.28e-1)" ATP7B WND ENSG00000123191 "ATPase copper transporting beta" P35670 13 51930436-52012125 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 10.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.2;Conjunctival goblet cells: 148.5;Early spermatids: 100.8;Late spermatids: 140.7;Mesothelial cells: 63.2;Salivary duct cells: 81.1;Salivary ionocytes: 82.1" "Cell type enhanced" "Detected in many" "Goblet cells: 148.5;Spermatogenic cell types: 140.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Hepatocytes: 384880.7;Large ducts: 187625.7;Pancreas epithelial cells: 181377.3" "Tissue enriched" "Detected in single" 180 "liver: 18038.4" "HPA009137, HPA013187" Supported Supported "Golgi apparatus" NA NA "Cluster 21: Testis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 104: Brain endothelial cells - Blood brain barrier" 10 "Golgi apparatus" "HPA009137: , HPA013187: " "unprognostic (1.21e-2)" "unprognostic (1.21e-1)" "unprognostic (4.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.53e-2)" "unprognostic (2.97e-1)" "unprognostic (3.81e-2)" "unprognostic (1.76e-1)" "potential prognostic favorable (3.74e-10)" "unprognostic (1.62e-2)" "unprognostic (1.74e-1)" "unprognostic (3.16e-1)" "unprognostic (1.68e-2)" "unprognostic (2.26e-1)" "unprognostic (1.33e-3)" "unprognostic (8.77e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-1)" "unprognostic (2.04e-1)" "unprognostic (3.13e-1)" "unprognostic (3.34e-1)" "unprognostic (2.00e-1)" "unprognostic (3.88e-2)" "unprognostic (4.34e-1)" "unprognostic (6.90e-2)" "unprognostic (4.67e-2)" "unprognostic (4.74e-1)" "unprognostic (2.09e-2)" ATP8A1 ATPIA ENSG00000124406 "ATPase phospholipid transporting 8A1" Q9Y2Q0 4 42408373-42657121 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 37.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 487.7;Brain inhibitory neurons: 488.4;Myonuclei: 700.5;Neutrophil progenitors: 709.7;Oligodendrocytes: 1233.4;Prostatic glandular cells: 484.1;Transitional alveolar cells: 621.5" "Cell type enhanced" "Detected in many" "Glial cells: 1233.4;Myocytes: 700.5;Neutrophils: 709.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1793.6" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 13.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 17.2" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 102544834.4;Microglia and Neuropil: 103219239.8;Neutrophils: 75186379.5" "Tissue enriched" "Detected in many" "cerebral cortex: 102363759.7" HPA052935 Enhanced Approved Vesicles,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 5 Cytosol Vesicles "HPA052935: " "unprognostic (9.69e-2)" "unprognostic (5.09e-3)" "unprognostic (3.64e-2)" "unprognostic (1.65e-1)" "unprognostic (2.08e-1)" "unprognostic (2.42e-2)" "unprognostic (4.80e-2)" "potential prognostic favorable (1.17e-9)" "unprognostic (7.64e-3)" "unprognostic (1.44e-1)" "unprognostic (7.14e-2)" "potential prognostic favorable (1.65e-4)" "unprognostic (1.46e-1)" "unprognostic (2.74e-3)" "unprognostic (1.19e-1)" "unprognostic (4.06e-1)" "unprognostic (1.84e-1)" "unprognostic (6.05e-2)" "unprognostic (3.87e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (4.22e-1)" "unprognostic (1.08e-1)" "unprognostic (8.65e-2)" "unprognostic (4.21e-1)" "unprognostic (4.33e-2)" ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 17.8;pituitary gland: 13.6;retina: 13.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 814.7;Brain inhibitory neurons: 644.7;Cone photoreceptor cells: 467.8;Corticotrophs: 656.6;Gonadotrophs: 1438.7;Lactotrophs: 936.6;Other brain neurons: 711.3;Retinal ganglion cells: 969.6;Rod photoreceptor cells: 961.6;Somatotrophs: 918.3;Thyrotrophs: 1198.2" "Group enriched" "Detected in many" 5 "Neuronal cells: 969.6;Pituitary endocrine cells: 1438.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 5.2" "Colon - Colon enteroendocrine cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22618 "Astrocytes and Neuropil: 2265763.5;Microglia and Neuropil: 2769450.6;Neurons: 1750246.7" "Tissue enhanced" "Detected in some" "cerebral cortex: 5334552.2" "HPA039926, HPA040033" Enhanced Supported "Nucleoplasm,Plasma membrane,Acrosome,Mid piece,Annulus" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Plasma membrane" "Nucleoplasm, Acrosome, Mid piece, Annulus" "HPA039926: , HPA040033: " "unprognostic (3.12e-2)" "unprognostic (1.99e-1)" "unprognostic (4.28e-2)" "unprognostic (2.34e-1)" "unprognostic (1.50e-1)" "unprognostic (1.37e-1)" ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 71.4" "Cell type enhanced" "Detected in many" "Foveolar cells: 566.4;Prostatic club cells: 660.3;Prostatic hillock cells: 589.2;Urothelial cells: 1235.8" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 1235.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Collecting ducts: 6499795.6;Fallopian tube cells: 2486556.5;Large ducts: 5362467.0;Pancreas epithelial cells: 6080243.4;Pancreatic islets: 7220862.0" "Tissue enhanced" "Detected in many" "intestine: 26801490.7" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 17: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: , HPA018674: " "unprognostic (1.79e-1)" "unprognostic (9.13e-2)" "unprognostic (7.27e-2)" "unprognostic (4.08e-2)" "potential prognostic favorable (8.40e-4)" "unprognostic (1.06e-3)" "unprognostic (1.20e-1)" "unprognostic (1.94e-3)" "unprognostic (2.70e-1)" "unprognostic (2.81e-1)" "validated prognostic favorable (4.75e-4)" "validated prognostic favorable (7.06e-6)" "unprognostic (1.41e-1)" "unprognostic (1.90e-1)" "unprognostic (3.14e-3)" "unprognostic (3.44e-2)" "unprognostic (7.25e-2)" "unprognostic (1.71e-1)" "unprognostic (9.68e-2)" "unprognostic (1.66e-1)" "unprognostic (7.26e-2)" "unprognostic (6.87e-3)" "unprognostic (3.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.36e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-1)" "unprognostic (2.49e-1)" "unprognostic (3.57e-1)" "unprognostic (1.36e-1)" "unprognostic (8.64e-2)" ATPAF2 "ATP12, Atp12p, LP3663, MGC29736" ENSG00000171953 "ATP synthase mitochondrial F1 complex assembly factor 2" Q8N5M1 17 17977409-18039209 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 96.0" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 18767987.1" "Tissue enhanced" "Detected in many" "heart muscle: 5125355.2" "HPA023329, HPA059422" Supported Uncertain Cytosol No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 78 Cytosol "HPA023329: , HPA059422: " "unprognostic (1.09e-1)" "unprognostic (2.49e-2)" "unprognostic (2.66e-1)" "unprognostic (2.60e-1)" "unprognostic (5.82e-2)" "unprognostic (9.80e-2)" "unprognostic (3.37e-1)" "potential prognostic favorable (3.02e-7)" "unprognostic (1.09e-1)" "unprognostic (6.15e-3)" "potential prognostic favorable (8.71e-7)" "unprognostic (1.84e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (6.33e-2)" "unprognostic (1.30e-1)" "unprognostic (1.44e-2)" "unprognostic (3.08e-2)" "unprognostic (2.68e-1)" "unprognostic (4.57e-1)" "unprognostic (2.17e-1)" "unprognostic (1.08e-1)" "unprognostic (4.83e-3)" "unprognostic (2.67e-3)" "unprognostic (5.75e-3)" "unprognostic (3.45e-2)" "unprognostic (1.95e-1)" "unprognostic (6.31e-2)" "unprognostic (2.58e-1)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (1.61e-1)" ATPSCKMT "FAM173B, JS-2" ENSG00000150756 "ATP synthase c subunit lysine N-methyltransferase" Q6P4H8 5 10225507-10249897 "Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Large ducts: 49384.0" "Not detected" "Not detected" HPA074513 Approved Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 3 "Nucleoplasm, Vesicles" "HPA074513: " "unprognostic (6.21e-2)" "potential prognostic unfavorable (1.37e-5)" "unprognostic (4.34e-2)" "unprognostic (1.35e-2)" "unprognostic (1.17e-2)" "unprognostic (1.67e-2)" "unprognostic (2.96e-1)" "unprognostic (5.05e-2)" "unprognostic (4.05e-1)" "potential prognostic favorable (6.34e-5)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (2.87e-2)" "unprognostic (2.22e-1)" "unprognostic (3.72e-2)" "unprognostic (2.51e-1)" "unprognostic (3.69e-2)" "unprognostic (9.47e-2)" "unprognostic (4.50e-2)" "unprognostic (7.76e-2)" "unprognostic (3.41e-1)" "unprognostic (4.60e-2)" "unprognostic (1.40e-3)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (2.21e-1)" "unprognostic (3.98e-1)" "unprognostic (2.42e-2)" "unprognostic (2.17e-1)" ATR "FRP1, MEC1, SCKL, SCKL1" ENSG00000175054 "ATR serine/threonine kinase" Q13535 3 142449007-142578733 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA damage, DNA repair" "DNA-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 373.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 2223190.1;T-cells: 1409274.9" "Tissue enriched" "Detected in single" 115 "intestine: 11508.1" HPA054320 Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 18: Adrenal cortex cells - Steroidogensis" 53 Nucleoplasm "Golgi apparatus" "HPA054320: " "unprognostic (8.65e-2)" "unprognostic (1.19e-1)" "unprognostic (1.73e-1)" "unprognostic (1.91e-2)" "unprognostic (1.87e-1)" "unprognostic (1.31e-1)" "unprognostic (1.43e-1)" "unprognostic (8.26e-2)" "unprognostic (1.96e-2)" "potential prognostic favorable (2.47e-5)" "unprognostic (6.13e-2)" "unprognostic (5.99e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-1)" "unprognostic (1.98e-3)" "unprognostic (2.84e-1)" "unprognostic (3.14e-1)" "unprognostic (4.17e-2)" "potential prognostic unfavorable (4.00e-4)" "unprognostic (3.98e-2)" "unprognostic (3.02e-1)" "unprognostic (2.09e-2)" "unprognostic (1.10e-1)" "unprognostic (2.07e-1)" "unprognostic (1.24e-1)" "unprognostic (3.45e-1)" "unprognostic (1.24e-2)" "unprognostic (8.60e-2)" ATXN1 "ATX1, D6S504E, SCA1" ENSG00000124788 "Ataxin 1" P54253 6 16299112-16761491 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1684.8;Neutrophils: 2569.1" "Cell type enhanced" "Detected in all" "Neutrophils: 2569.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 22868790.4" "Tissue enriched" "Detected in some" "fallopian tube: 597123.9" "HPA008335, HPA070756" Approved Supported Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 28: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 401 Nucleoplasm "Nucleoli, Cytosol" "HPA008335: , HPA070756: " "unprognostic (3.81e-2)" "unprognostic (1.71e-1)" "unprognostic (1.29e-1)" "unprognostic (2.55e-2)" "unprognostic (2.12e-1)" "unprognostic (1.05e-1)" "unprognostic (2.76e-1)" "unprognostic (4.57e-2)" "unprognostic (5.49e-2)" "unprognostic (4.63e-2)" "validated prognostic favorable (1.78e-5)" "validated prognostic favorable (1.01e-4)" "unprognostic (1.84e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-1)" "unprognostic (7.92e-2)" "unprognostic (2.12e-2)" "unprognostic (5.53e-2)" "unprognostic (1.21e-1)" "unprognostic (3.45e-1)" "unprognostic (2.34e-1)" "unprognostic (9.54e-2)" "unprognostic (5.25e-2)" "unprognostic (1.15e-1)" "unprognostic (6.37e-2)" "unprognostic (3.34e-2)" "unprognostic (1.47e-1)" "unprognostic (9.65e-2)" "unprognostic (2.70e-1)" "unprognostic (1.25e-2)" "unprognostic (1.78e-1)" AURKA "AIK, ARK1, AurA, BTAK, PPP1R47, STK15, STK6, STK7" ENSG00000087586 "Aurora kinase A" O14965 20 56369389-56392337 "Cancer-related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.6;testis: 28.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 49.5;Erythrocyte progenitors: 61.8;Extravillous trophoblasts: 77.4;Late primary spermatocytes: 269.3;Migrating cytotrophoblasts: 57.4;Monocyte progenitors: 90.0;Oocytes: 354.6" "Cell type enhanced" "Detected in many" "Oocytes: 354.6;Spermatogenic cell types: 269.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 22170 "intestine: 2217027.3" "CAB001454, HPA002636" Enhanced Supported "Nucleoplasm,Mitotic spindle,Centrosome,Basal body,Cytosol" Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 147 "Mitotic spindle, Centrosome, Basal body" "Nucleoplasm, Cytosol" "CAB001454: , HPA002636: " "unprognostic (7.08e-3)" "unprognostic (2.22e-2)" "unprognostic (7.02e-2)" "unprognostic (1.67e-1)" "unprognostic (3.90e-2)" "unprognostic (1.16e-2)" "unprognostic (1.99e-1)" "unprognostic (3.96e-2)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (9.06e-7)" "validated prognostic unfavorable (2.02e-7)" "validated prognostic unfavorable (6.11e-6)" "potential prognostic unfavorable (1.01e-5)" "validated prognostic unfavorable (4.15e-5)" "validated prognostic unfavorable (1.47e-9)" "potential prognostic unfavorable (6.92e-5)" "unprognostic (8.87e-3)" "unprognostic (2.32e-2)" "unprognostic (1.22e-1)" "unprognostic (9.22e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (6.72e-3)" "unprognostic (4.75e-2)" "unprognostic (3.41e-2)" "unprognostic (6.65e-3)" "unprognostic (2.60e-2)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (5.78e-3)" "unprognostic (7.53e-2)" AURKB "Aik2, AIM-1, ARK2, AurB, IPL1, PPP1R48, STK12, STK5" ENSG00000178999 "Aurora kinase B" Q96GD4 17 8204733-8210600 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.6;lymphoid tissue: 55.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 46.7;Enteric transient amplifying cells: 60.0;Erythrocyte progenitors: 49.5;Esophageal basal cells: 59.6;Extravillous trophoblasts: 102.8;Gastric progenitor cells: 28.2;Hofbauer cells: 48.5;Megakaryocyte progenitors: 41.1;Migrating cytotrophoblasts: 77.2;Monocyte progenitors: 80.5;Neutrophil progenitors: 29.6" "Cell type enhanced" "Detected in many" "Basal cells: 59.6;Erythrocytes: 49.5;Mononuclear phagocytes: 80.5;Proliferating cells: 60.0;Trophoblast cells: 102.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 7.9" "Group enriched" "Detected in many" 6 "B-cells: 2.5;T-cells: 7.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Group enriched" "Detected in some" 5 "basal ganglia: 1.3;white matter: 4.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 685835.5" "Not detected" "Not detected" "CAB005862, HPA037708" Enhanced Supported Nucleoplasm,Kinetochore,Midbody Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 151 Nucleoplasm "Kinetochore, Midbody" "CAB005862: , HPA037708: " "unprognostic (1.96e-2)" "unprognostic (5.09e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-2)" "unprognostic (1.25e-1)" "unprognostic (5.70e-2)" "unprognostic (2.67e-1)" "unprognostic (8.70e-3)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (3.78e-6)" "validated prognostic unfavorable (3.24e-10)" "validated prognostic unfavorable (5.06e-4)" "potential prognostic unfavorable (2.76e-9)" "validated prognostic unfavorable (3.33e-5)" "validated prognostic unfavorable (1.20e-8)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (2.38e-3)" "unprognostic (2.47e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.75e-2)" "unprognostic (2.95e-3)" "unprognostic (8.10e-3)" "unprognostic (1.37e-3)" "unprognostic (1.15e-1)" "unprognostic (1.10e-1)" "unprognostic (1.30e-2)" "unprognostic (7.08e-2)" "unprognostic (1.80e-1)" "unprognostic (3.32e-2)" "unprognostic (1.22e-1)" AUTS2 "FBRSL2, KIAA0442" ENSG00000158321 "Activator of transcription and developmental regulator AUTS2" Q8WXX7 7 69598296-70793506 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Autism, Autism spectrum disorder, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 2209.8;Lactotrophs: 2233.2;Retinal amacrine cells: 2094.1;Retinal horizontal cells: 3439.8;Somatotrophs: 1998.2" "Cell type enhanced" "Detected in all" "Neuronal cells: 3439.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 8.0;naive B-cell: 9.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 782 "Neurons: 78174.3" "Group enriched" "Detected in some" "blood vessel: 316330.1;intestine: 230143.7;lymphoid tissue: 108033.5" HPA000390 Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 21 Nucleoplasm "Plasma membrane, Cell Junctions, Cytosol" "HPA000390: " "unprognostic (1.48e-1)" "unprognostic (2.57e-1)" "unprognostic (3.87e-1)" "unprognostic (1.68e-1)" "unprognostic (1.51e-1)" "unprognostic (5.48e-2)" "unprognostic (7.86e-2)" "unprognostic (8.92e-2)" "unprognostic (3.53e-2)" "unprognostic (3.52e-2)" "validated prognostic favorable (9.09e-9)" "validated prognostic favorable (8.25e-5)" "unprognostic (6.50e-3)" "unprognostic (5.43e-2)" "potential prognostic favorable (5.50e-4)" "unprognostic (1.09e-1)" "unprognostic (5.82e-2)" "unprognostic (1.01e-1)" "unprognostic (8.43e-2)" "unprognostic (7.63e-2)" "unprognostic (8.71e-2)" "unprognostic (1.68e-1)" "unprognostic (1.03e-2)" "unprognostic (3.23e-1)" "unprognostic (1.33e-2)" "unprognostic (4.51e-3)" "unprognostic (2.55e-2)" "unprognostic (2.55e-2)" "unprognostic (1.74e-1)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" AXDND1 "C1orf125, FLJ32940" ENSG00000162779 "Axonemal dynein light chain domain containing 1" Q5T1B0 1 179365720-179554735 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 14.7" "Cell type enhanced" "Detected in many" "Early spermatids: 242.0;Ependymal cells: 92.5;Foveolar cells: 62.4;Late primary spermatocytes: 246.0;Late spermatids: 425.1" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 425.1" "Cell type enriched" "Detected in many" 5 "ependymal cell: 90.1" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8687 "Distal tubules: 792641.7;Large ducts: 944783.7" "Not detected" "Not detected" HPA071114 Enhanced Approved "Primary cilium,Basal body,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 3: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Primary cilium, Cytosol" "Basal body" "HPA071114: " "unprognostic (2.41e-1)" "unprognostic (1.00e-2)" AXIN1 PPP1R49 ENSG00000103126 "Axin 1" O15169 16 287440-352723 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 91.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 44 "Glomeruli: 5093.6;Large ducts: 4092.6;Proximal tubules: 3939.0" "Tissue enriched" "Detected in single" 2332 "cerebral cortex: 233196.1" "CAB012987, HPA056522" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Primary cilium,Primary cilium tip,Primary cilium transition zone" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 93 "Nucleoplasm, Vesicles, Primary cilium" "Nucleoli, Primary cilium tip, Primary cilium transition zone" "CAB012987: , HPA056522: " "unprognostic (1.84e-1)" "unprognostic (7.52e-2)" "unprognostic (8.55e-2)" "unprognostic (2.54e-2)" "unprognostic (3.18e-1)" "unprognostic (3.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.88e-3)" "unprognostic (1.03e-1)" "unprognostic (3.25e-1)" "unprognostic (3.96e-1)" "unprognostic (1.67e-1)" "unprognostic (1.85e-1)" "validated prognostic unfavorable (1.43e-6)" "validated prognostic unfavorable (4.18e-4)" "unprognostic (8.18e-2)" "unprognostic (3.17e-2)" "unprognostic (3.47e-1)" "unprognostic (2.38e-3)" "unprognostic (9.14e-2)" "unprognostic (4.17e-1)" "unprognostic (2.23e-2)" "unprognostic (1.28e-1)" "unprognostic (1.17e-2)" "potential prognostic favorable (4.32e-4)" "unprognostic (8.32e-2)" "unprognostic (1.49e-1)" "unprognostic (3.22e-2)" "unprognostic (2.55e-1)" "unprognostic (2.58e-2)" "unprognostic (6.50e-2)" AZGP1 "ZA2G, ZAG" ENSG00000160862 "Alpha-2-glycoprotein 1, zinc-binding" P25311 7 99966720-99976042 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 2621.1;salivary gland: 3617.4" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 2494.0;Hepatocytes: 5184.7;Lacrimal acinar cells: 7814.6;Prostatic club cells: 1114.4;Prostatic glandular cells: 4092.7;Salivary acinar cells: 4571.1;Salivary duct cells: 949.0;Salivary myoepithelial cells: 1409.4" "Cell type enhanced" "Detected in many" "Acinar cells: 7814.6;Glandular cells: 4092.7;Hepatocytes: 5184.7;Luminal cells: 2494.0" "Group enriched" "Detected in some" 6 "Bergmann glia: 3.2;choroid plexus epithelial cell: 3.1;committed oligodendrocyte precursor: 5.1;oligodendrocyte: 11.4;oligodendrocyte precursor cell: 3.9" "Group enriched" "Detected in many" 10 "Breast Invasive Carcinoma (TCGA): 1562.4;Liver Hepatocellular Carcinoma (TCGA): 857.6;Prostate Adenocarcinoma (TCGA): 1716.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 226.3;prostate cancer: 78.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA012582, HPA012876, CAB016087, CAB032276" Enhanced Approved Nucleoplasm,Vesicles "Secreted to blood" "No annotated function" NA NA 55200000000 17000000000 "Cluster 70: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 31 Vesicles Nucleoplasm "CAB016087: , CAB032276: , HPA012582: , HPA012876: " "unprognostic (2.60e-3)" "unprognostic (1.70e-1)" "unprognostic (2.48e-1)" "unprognostic (1.49e-1)" "unprognostic (2.19e-1)" "unprognostic (1.01e-1)" "unprognostic (1.15e-2)" "unprognostic (3.67e-2)" "unprognostic (1.88e-2)" "unprognostic (2.28e-1)" "potential prognostic favorable (2.53e-4)" "unprognostic (3.62e-2)" "unprognostic (1.32e-2)" "unprognostic (1.39e-3)" "unprognostic (1.30e-2)" "unprognostic (4.84e-2)" "unprognostic (6.17e-3)" "unprognostic (7.89e-3)" "unprognostic (1.33e-1)" "unprognostic (1.85e-1)" "unprognostic (2.48e-1)" "unprognostic (2.78e-2)" "unprognostic (1.50e-1)" "unprognostic (2.71e-1)" "unprognostic (8.77e-2)" "unprognostic (1.79e-1)" "unprognostic (4.35e-2)" "unprognostic (2.14e-1)" "unprognostic (1.56e-1)" "unprognostic (6.31e-2)" AZU1 "AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC" ENSG00000172232 "Azurocidin 1" P20160 19 825097-832018 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Antibiotic, Antimicrobial, Heparin-binding, Serine protease homolog" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 46 "bone marrow: 1507.5" "Group enriched" "Detected in some" 65 "Monocyte progenitors: 423.6;Neutrophil progenitors: 473.3" "Group enriched" "Detected in some" 65 "Mononuclear phagocytes: 423.6;Neutrophils: 473.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "neutrophil: 3.3" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.3" "Cancer enriched" "Detected in single" 40 "Leukemia: 39.1" "Breast - Breast glandular cells, Liver - Erythroid cells, Lung - Neutrophils_1, Spleen - Neutrophils_1" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Neutrophils: 815182915.8" "Tissue enhanced" "Detected in all" "lung: 77998765.9" "HPA055851, HPA075964" Enhanced Enhanced Vesicles "Secreted to blood" Defense NA NA 13700000 7000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 7 Vesicles "HPA055851: , HPA075964: " "unprognostic (3.70e-2)" "unprognostic (4.95e-2)" "unprognostic (1.00e-1)" B3GNT5 "B3GN-T5, beta3Gn-T5" ENSG00000176597 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5" Q9BYG0 3 183253253-183298504 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 72.3" "Cell type enhanced" "Detected in many" "Colonocytes: 305.9;Esophageal apical cells: 652.4;Esophageal suprabasal cells: 342.1;Microglia: 316.1;Neutrophils: 584.1;Ocular epithelial cells: 442.4;Syncytiotrophoblasts: 320.7;Urothelial cells: 382.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 652.4;Neutrophils: 584.1" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 360.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 5.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 5.6" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Region enriched" "Detected in many" 4 "cerebellum: 14.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA017292 Uncertain Approved Nucleoli NA NA 13000 "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Nucleoli "HPA017292: " "unprognostic (2.42e-1)" "unprognostic (2.68e-1)" "unprognostic (2.26e-1)" "unprognostic (2.52e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (3.32e-5)" "unprognostic (3.12e-1)" "potential prognostic unfavorable (6.82e-5)" "unprognostic (1.82e-2)" "unprognostic (8.69e-3)" "unprognostic (8.50e-2)" "unprognostic (3.29e-1)" "unprognostic (8.98e-3)" "unprognostic (3.74e-3)" "unprognostic (1.34e-1)" "validated prognostic unfavorable (1.18e-4)" "validated prognostic unfavorable (5.98e-5)" "unprognostic (4.79e-2)" "unprognostic (1.99e-2)" "unprognostic (2.42e-1)" "unprognostic (3.42e-1)" "validated prognostic unfavorable (4.15e-4)" "validated prognostic unfavorable (2.55e-4)" "unprognostic (2.90e-1)" "unprognostic (1.53e-1)" "unprognostic (2.60e-2)" "unprognostic (2.26e-1)" "unprognostic (5.37e-2)" "unprognostic (1.79e-1)" "unprognostic (2.85e-2)" "unprognostic (1.04e-3)" B3GNTL1 B3GNT8 ENSG00000175711 "UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase like 1" Q67FW5 17 82942149-83051809 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 5.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 30.4;Epididymal principal cells: 27.4;Late spermatids: 28.3;Neutrophils: 42.4;Oocytes: 27.6" "Cell type enhanced" "Detected in many" "Neutrophils: 42.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 6.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Oocytes: 680406.4" "Not detected" "Not detected" "HPA023585, HPA024547" Supported Approved "Nucleoli,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Nucleoli, Nucleoli fibrillar center" Vesicles "HPA023585: , HPA024547: " "unprognostic (1.49e-1)" "unprognostic (7.61e-3)" "unprognostic (2.02e-2)" "unprognostic (5.51e-2)" "unprognostic (1.62e-1)" "unprognostic (3.21e-1)" "unprognostic (1.00e-1)" "unprognostic (1.64e-2)" "unprognostic (1.04e-2)" "unprognostic (2.36e-1)" "validated prognostic unfavorable (2.78e-7)" "validated prognostic unfavorable (3.63e-4)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.13e-7)" "unprognostic (1.39e-3)" "unprognostic (5.34e-2)" "unprognostic (1.46e-1)" "unprognostic (2.84e-1)" "unprognostic (3.11e-2)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (2.62e-1)" "unprognostic (1.41e-1)" "unprognostic (7.00e-2)" "unprognostic (2.54e-1)" "unprognostic (1.64e-1)" "unprognostic (1.53e-1)" "unprognostic (2.37e-2)" "unprognostic (3.51e-1)" "unprognostic (7.38e-2)" "unprognostic (2.06e-1)" B4GALNT3 "B4GalNac-T3, FLJ16224, FLJ40362" ENSG00000139044 "Beta-1,4-N-acetyl-galactosaminyltransferase 3" Q6L9W6 12 459939-563509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 22.4;stomach 1: 57.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 348.1;Colonocytes: 347.7;Endometrial glandular cells: 546.2;Foveolar cells: 977.2;Ocular epithelial cells: 562.0;Suprabasal keratinocytes: 493.8;Thyrotrophs: 349.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 562.0;Gastric glandular cells: 977.2;Glandular cells: 546.2;Suprabasal cells: 493.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Alveolar cell types: 896284.5;Collecting ducts: 1209684.9;Distal tubules: 2470395.2;Pancreatic islets: 1072197.5" "Not detected" "Not detected" HPA011404 Enhanced Supported "Golgi apparatus,Vesicles" NA NA "Cluster 17: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 1 "Golgi apparatus" Vesicles "HPA011404: " "unprognostic (7.42e-3)" "unprognostic (1.95e-1)" "unprognostic (6.25e-2)" "unprognostic (2.06e-1)" "unprognostic (1.22e-2)" "unprognostic (1.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-1)" "unprognostic (3.47e-1)" "unprognostic (1.04e-1)" "unprognostic (9.39e-2)" "unprognostic (8.52e-2)" "unprognostic (1.67e-1)" "unprognostic (7.90e-3)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (4.97e-1)" "unprognostic (3.29e-2)" "unprognostic (9.76e-2)" "unprognostic (9.87e-2)" "unprognostic (5.47e-2)" "unprognostic (1.02e-2)" "unprognostic (2.91e-1)" "unprognostic (3.08e-1)" "unprognostic (5.52e-2)" "unprognostic (3.03e-1)" "unprognostic (1.72e-1)" "unprognostic (2.28e-1)" B4GALT1 "beta4Gal-T1, GGTB2" ENSG00000086062 "Beta-1,4-galactosyltransferase 1" P15291 9 33104082-33167356 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 1650.3;Neutrophils: 1062.1" "Cell type enhanced" "Detected in all" "Neutrophils: 1062.1;Secretory cells: 1650.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 195.8;endothelial cell: 198.7;leukocyte: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 215.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 4569275.0" "Tissue enhanced" "Detected in all" "salivary gland: 6736828.6" "HPA010806, HPA010807" Enhanced Enhanced "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 22000000 "Cluster 30: Non-specific - DNA binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 "Golgi apparatus" "HPA010806: , HPA010807: " "unprognostic (2.40e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (3.79e-3)" "unprognostic (3.76e-2)" "potential prognostic unfavorable (7.32e-4)" "unprognostic (4.50e-3)" "unprognostic (1.32e-2)" "unprognostic (1.72e-1)" "unprognostic (2.04e-2)" "unprognostic (4.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.96e-1)" "unprognostic (3.97e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (1.29e-2)" "unprognostic (8.04e-2)" "unprognostic (1.25e-1)" "unprognostic (3.43e-1)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (1.93e-2)" "unprognostic (3.88e-1)" "unprognostic (2.24e-1)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (5.10e-2)" "unprognostic (3.99e-2)" "unprognostic (4.30e-2)" "unprognostic (6.20e-2)" B4GALT5 beta4GalT-V ENSG00000158470 "Beta-1,4-galactosyltransferase 5" O43286 20 49632945-49713878 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 673.6;Neutrophil progenitors: 1670.6;Neutrophils: 1511.7;Ocular epithelial cells: 681.8;Urothelial cells: 733.9" "Cell type enhanced" "Detected in all" "Neutrophils: 1670.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.6" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neutrophils: 3018389.0" "Tissue enriched" "Detected in some" "Stomach: 471539.4" HPA077777 Approved Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Vesicles "HPA077777: " "unprognostic (1.69e-2)" "unprognostic (8.62e-2)" "unprognostic (9.39e-2)" "unprognostic (3.05e-2)" "unprognostic (1.03e-1)" "unprognostic (3.08e-2)" "unprognostic (2.81e-1)" "unprognostic (1.21e-1)" "unprognostic (8.84e-2)" "unprognostic (3.94e-2)" "unprognostic (2.54e-3)" "unprognostic (1.09e-1)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (3.80e-3)" "unprognostic (9.96e-2)" "unprognostic (9.22e-3)" "unprognostic (1.83e-1)" "unprognostic (3.79e-1)" "unprognostic (1.53e-2)" "unprognostic (8.86e-3)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (3.41e-3)" "unprognostic (1.67e-1)" "unprognostic (7.61e-3)" "unprognostic (2.34e-2)" "unprognostic (2.53e-1)" "unprognostic (3.59e-2)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (1.83e-1)" B9D1 "B9, EPPB9, MKS9, MKSR-1" ENSG00000108641 "B9 domain containing 1" Q9UPM9 17 19334308-19378193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 212.9;Epicardial cells: 127.4;Epididymal efferent duct ciliated cells: 177.1;Epididymal principal cells: 132.8;Fallopian tube ciliated cells: 235.6;Late primary spermatocytes: 334.1;Late spermatids: 223.8;Respiratory ciliated cells: 256.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 256.9;Spermatogenic cell types: 334.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 3435700.2" "Tissue enriched" "Detected in some" "fallopian tube: 1361615.9" HPA022957 Approved Uncertain "Nucleoplasm,Vesicles,Basal body,Cytosol,Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 12 "Nucleoplasm, Acrosome, Equatorial segment, Mid piece" "Vesicles, Basal body, Cytosol, Principal piece, End piece" "HPA022957: " "unprognostic (8.06e-3)" "unprognostic (2.45e-1)" "unprognostic (5.70e-1)" "unprognostic (6.04e-3)" "unprognostic (2.35e-2)" "unprognostic (3.65e-1)" "unprognostic (8.88e-3)" "unprognostic (1.15e-1)" "unprognostic (2.23e-2)" "unprognostic (3.68e-2)" "unprognostic (2.01e-3)" "unprognostic (2.66e-1)" "potential prognostic favorable (2.13e-8)" "unprognostic (1.93e-3)" "unprognostic (7.68e-3)" "unprognostic (2.55e-1)" "unprognostic (2.72e-2)" "unprognostic (3.11e-1)" "unprognostic (1.03e-1)" "unprognostic (2.18e-1)" "unprognostic (5.95e-2)" "unprognostic (1.13e-2)" "unprognostic (7.75e-2)" "unprognostic (2.16e-1)" "unprognostic (3.65e-1)" "unprognostic (1.87e-1)" "unprognostic (2.64e-1)" "unprognostic (7.88e-2)" "unprognostic (9.89e-2)" "unprognostic (7.04e-2)" "unprognostic (6.16e-2)" B9D2 "MGC4093, MKS10, MKSR-2" ENSG00000123810 "B9 domain containing 2" Q9BPU9 19 41354417-41364165 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 64.0;Epididymal efferent duct ciliated cells: 52.5;Fallopian tube ciliated cells: 79.9;Late spermatids: 56.1;Respiratory ciliated cells: 95.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 95.9" "Cell type enhanced" "Detected in many" "ependymal cell: 9.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 128.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 16502 "Fallopian tube cells: 1650224.5" "Tissue enriched" "Detected in single" 2639 "fallopian tube: 263882.0" "HPA042229, HPA042618" Enhanced Uncertain "Nucleoli,Golgi apparatus,Vesicles,Centrosome,Basal body" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 27 "Nucleoli, Golgi apparatus" "Vesicles, Centrosome, Basal body" "HPA042229: , HPA042618: " "unprognostic (2.87e-1)" "unprognostic (1.96e-1)" "unprognostic (1.52e-2)" "potential prognostic favorable (1.95e-4)" "unprognostic (1.21e-1)" "unprognostic (5.46e-3)" "unprognostic (7.34e-2)" "unprognostic (1.08e-1)" "unprognostic (3.24e-3)" "unprognostic (4.29e-2)" "potential prognostic favorable (1.16e-5)" "unprognostic (1.45e-1)" "unprognostic (6.39e-2)" "unprognostic (5.47e-3)" "potential prognostic favorable (8.08e-4)" "unprognostic (2.55e-1)" "unprognostic (1.93e-1)" "unprognostic (2.18e-1)" "unprognostic (2.60e-1)" "unprognostic (1.75e-1)" "unprognostic (1.61e-2)" "unprognostic (2.78e-2)" "unprognostic (3.45e-2)" "unprognostic (3.33e-1)" "unprognostic (1.16e-1)" "unprognostic (4.24e-2)" "unprognostic (5.81e-3)" "unprognostic (1.08e-1)" "unprognostic (3.49e-1)" "unprognostic (1.44e-1)" "unprognostic (1.42e-1)" BAALC ENSG00000164929 "BAALC binder of MAP3K1 and KLF4" Q8WXS3 8 103140713-103230305 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 274.0" "Cell type enhanced" "Detected in many" "Astrocytes: 293.3;Bergmann glia: 407.4;Endometrial luminal cells: 93.8;Hematopoietic stem cells: 100.4;Lactotrophs: 117.3;Müller glia: 130.0;Oligodendrocyte progenitor cells: 234.4;Pituitary stem cells: 118.8;Somatotrophs: 86.0;Thymocytes: 227.0;Thyrotrophs: 92.6" "Cell type enhanced" "Detected in many" "Glial cells: 407.4;T-cells: 227.0" "Cell type enhanced" "Detected in all" "Bergmann glia: 413.3" "Cancer enriched" "Detected in many" 8 "Glioblastoma Multiforme (TCGA): 339.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 28 "NK-cell: 3.7" "Lineage enriched" "Detected in single" 28 "NK-cells: 3.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10208 "Astrocytes and Neuropil: 837005.6;Microglia and Neuropil: 1086292.7;Neurons: 1139062.0" "Tissue enriched" "Detected in single" 32022 "cerebral cortex: 3202150.0" "HPA027132, HPA068307" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 14: Non-specific - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 2 Cytosol Nucleoplasm "HPA027132: , HPA068307: " "unprognostic (2.68e-1)" "unprognostic (1.54e-1)" "unprognostic (2.28e-1)" "unprognostic (3.88e-3)" "unprognostic (3.40e-1)" "unprognostic (2.39e-2)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.38e-1)" "unprognostic (3.11e-2)" "unprognostic (1.89e-1)" "unprognostic (5.81e-1)" "unprognostic (1.10e-1)" "unprognostic (2.19e-2)" "unprognostic (8.23e-2)" "unprognostic (5.06e-2)" "unprognostic (2.56e-1)" "unprognostic (1.55e-1)" "unprognostic (1.68e-2)" "unprognostic (1.88e-2)" "unprognostic (7.21e-3)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (1.02e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.83e-1)" "unprognostic (2.90e-1)" "unprognostic (8.74e-2)" BABAM1 "C19orf62, FLJ20571, HSPC142, MERIT40, NBA1" ENSG00000105393 "BRISC and BRCA1 A complex member 1" Q9NWV8 19 17267376-17281249 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Ubl conjugation pathway" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 14.9;Bergmann glia: 20.0;Brain excitatory neurons: 27.9;Brain inhibitory neurons: 23.8;Choroid plexus epithelial cells: 10.5;Microglia: 20.2;Oligodendrocyte progenitor cells: 20.2;Oligodendrocytes: 22.2;Other brain neurons: 28.0;Parietal cells: 10.6" "Cell type enhanced" "Detected in many" "Glial cells: 22.2;Neuronal cells: 28.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 10069500.3" "Low tissue specificity" "Detected in all" "HPA054386, HPA068786, HPA077609" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 21 "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA054386: , HPA068786: , HPA077609: " "unprognostic (4.91e-2)" "unprognostic (1.47e-1)" "unprognostic (2.28e-1)" "unprognostic (1.44e-1)" "unprognostic (7.90e-2)" "unprognostic (5.23e-2)" "unprognostic (7.64e-2)" "unprognostic (2.12e-1)" "unprognostic (2.33e-2)" "unprognostic (1.74e-3)" "unprognostic (1.39e-1)" "unprognostic (2.53e-2)" "unprognostic (3.04e-3)" "unprognostic (1.71e-3)" "unprognostic (2.09e-1)" "unprognostic (2.28e-1)" "unprognostic (1.69e-2)" "unprognostic (1.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (1.96e-1)" "unprognostic (6.39e-2)" "unprognostic (4.79e-2)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (1.50e-1)" "unprognostic (2.87e-1)" "unprognostic (3.22e-2)" "unprognostic (1.19e-1)" BACH1 "BACH-1, BTBD24" ENSG00000156273 "BTB domain and CNC homolog 1" O14867 21 29194071-29630751 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.3" "Cell type enhanced" "Detected in all" "Late spermatids: 651.8;monocytes: 779.7;Neutrophils: 948.0;Podocytes: 816.6" "Cell type enhanced" "Detected in all" "Neutrophils: 948.0" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 670.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 151.1" "Group enriched" "Detected in all" 4 "granulocytes: 151.1;monocytes: 51.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 915425.7" "Group enriched" "Detected in some" 10471 "lung: 1671506.4;lymphoid tissue: 422654.9" HPA034949 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 69: Skin cancer - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 54 Nucleoplasm Cytosol "HPA034949: " "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.39e-1)" "unprognostic (1.84e-3)" "unprognostic (2.98e-1)" "unprognostic (1.73e-2)" "unprognostic (2.13e-1)" "unprognostic (2.22e-1)" "unprognostic (2.06e-1)" "unprognostic (4.87e-2)" "unprognostic (3.75e-2)" "unprognostic (3.12e-1)" "unprognostic (9.27e-3)" "unprognostic (2.26e-3)" "unprognostic (5.26e-3)" "unprognostic (3.91e-3)" "unprognostic (2.36e-3)" "unprognostic (1.80e-1)" "unprognostic (1.22e-1)" "unprognostic (6.18e-3)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (7.45e-4)" "unprognostic (7.55e-3)" "unprognostic (6.35e-2)" "unprognostic (2.37e-1)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" "unprognostic (5.60e-2)" "unprognostic (1.59e-1)" "unprognostic (7.53e-3)" "unprognostic (4.50e-2)" BAG2 ENSG00000112208 "BAG cochaperone 2" O95816 6 57172326-57189833 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 101.3;Decidual stromal cells: 154.4;Early spermatids: 129.0;Late primary spermatocytes: 276.1;Oocytes: 92.1;Smooth muscle cells: 203.3" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 203.3;Spermatogenic cell types: 276.1;Stromal cells: 154.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 29066274.4" "Tissue enhanced" "Detected in all" "intestine: 124103166.4" "HPA018862, HPA019918" Enhanced Approved "Centrosome,Basal body,Cytosol,Mid piece,Principal piece" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 160 Cytosol "Centrosome, Basal body, Mid piece, Principal piece" "HPA018862: , HPA019918: " "unprognostic (5.39e-3)" "unprognostic (3.37e-1)" "unprognostic (1.48e-1)" "unprognostic (9.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.36e-1)" "unprognostic (9.44e-2)" "unprognostic (8.47e-2)" "unprognostic (2.79e-2)" "unprognostic (2.44e-2)" "unprognostic (1.13e-3)" "unprognostic (5.85e-2)" "unprognostic (6.68e-3)" "validated prognostic unfavorable (3.75e-7)" "validated prognostic unfavorable (5.22e-6)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (5.35e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (5.59e-3)" "unprognostic (5.53e-2)" "unprognostic (7.53e-2)" "unprognostic (8.48e-2)" "unprognostic (2.68e-2)" "unprognostic (8.89e-3)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (3.28e-3)" "unprognostic (2.80e-1)" "potential prognostic unfavorable (1.93e-5)" "unprognostic (6.98e-2)" BAG3 ENSG00000151929 "BAG cochaperone 3" O95817 10 119651380-119677819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis Chaperone "Cardiomyopathy, Charcot-Marie-Tooth disease, Disease variant, Myofibrillar myopathy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 489.5" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 329.9;monocytes: 343.2;Pancreatic acinar cells: 323.9;Pancreatic duct cells: 591.8;Smooth muscle cells: 299.5;Thymic myoid cells: 316.8" "Cell type enhanced" "Detected in all" "Ductal cells: 591.8" "Cell type enhanced" "Detected in many" "astrocyte: 92.5;endothelial cell: 94.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 4.1" "Lineage enriched" "Detected in single" 6 "T-cells: 4.1" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Capillaries: 67785519.8;Cardiomyocytes: 98318553.5;Skeletal myofibers: 241032783.8;Smooth muscle cells: 80442475.8" "Tissue enhanced" "Detected in all" "skeletal muscle: 291377926.6" "HPA018493, HPA020586" Enhanced Supported "Nucleoplasm,Basal body,Cytosol" NA NA 200000 "Cluster 31: T-cells - T-cell receptor" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 75: Non-specific - Chaperones and protein folding" 216 Cytosol "Nucleoplasm, Basal body" "HPA018493: , HPA020586: " "unprognostic (6.29e-2)" "unprognostic (6.15e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (9.56e-2)" "unprognostic (4.02e-2)" "unprognostic (5.04e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (6.13e-8)" "unprognostic (4.04e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (4.63e-2)" "unprognostic (3.92e-3)" "potential prognostic unfavorable (5.92e-7)" "unprognostic (9.94e-2)" "unprognostic (8.98e-2)" "unprognostic (4.88e-3)" "unprognostic (5.68e-2)" "unprognostic (2.41e-3)" "unprognostic (6.78e-3)" "unprognostic (2.63e-1)" "unprognostic (2.60e-2)" "unprognostic (1.09e-1)" "unprognostic (7.91e-2)" "unprognostic (5.84e-2)" "unprognostic (5.15e-2)" "unprognostic (3.42e-2)" "unprognostic (3.09e-2)" BAG6 "BAT3, D6S52E, G3, Scythe" ENSG00000204463 "BAG cochaperone 6" P46379 6 31639028-31652705 "Predicted intracellular proteins" "Apoptosis, Differentiation, Immunity, Spermatogenesis, Transport" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 218.9;Late primary spermatocytes: 250.0;Late spermatids: 612.0" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 612.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB020704, HPA045116, HPA053291" Enhanced Supported Nucleoplasm,Vesicles,Cytosol "Intracellular and membrane" Transport NA NA 260000 "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 94 Nucleoplasm "Vesicles, Cytosol" "CAB020704: , HPA045116: , HPA053291: " "unprognostic (3.77e-1)" "unprognostic (9.53e-2)" "unprognostic (2.59e-1)" "unprognostic (2.18e-1)" "unprognostic (1.68e-1)" "unprognostic (5.18e-3)" "unprognostic (2.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-3)" "unprognostic (1.20e-1)" "unprognostic (4.27e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (6.64e-4)" "unprognostic (5.71e-2)" "unprognostic (7.55e-2)" "unprognostic (6.51e-2)" "unprognostic (5.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (7.65e-2)" "unprognostic (8.20e-3)" "unprognostic (1.28e-2)" "unprognostic (6.72e-2)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (3.41e-1)" "unprognostic (1.72e-1)" "unprognostic (1.26e-1)" "unprognostic (1.45e-1)" BAMBI NMA ENSG00000095739 "BMP and activin membrane bound inhibitor" Q13145 10 28677510-28682932 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 290.5;Breast myoepithelial cells: 106.8;Breast secretory cells: 185.0;Epididymal basal cells: 93.9;Epididymal efferent duct absorptive cells: 107.9;Granulosa cells: 83.5;Müller glia: 96.4;Platelets: 100.5" "Cell type enhanced" "Detected in many" "Luminal cells: 290.5;Secretory cells: 185.0" "Group enriched" "Detected in many" 6 "astrocyte: 25.7;committed oligodendrocyte precursor: 82.3;endothelial cell: 76.5;ependymal cell: 46.4;oligodendrocyte: 25.7;oligodendrocyte precursor cell: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 329.6" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010819, HPA010866" Approved Approved "Nucleoli fibrillar center,Vesicles,Lipid droplets" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 30: White matter - Myelination" "Cluster 32: Non-specific - Cell proliferation" "Cluster 108: Fibroblasts - ECM organization" 2 Vesicles "Nucleoli fibrillar center, Lipid droplets" "HPA010819: , HPA010866: " "unprognostic (2.92e-2)" "unprognostic (2.54e-3)" "unprognostic (2.82e-1)" "unprognostic (1.26e-1)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (7.95e-4)" "unprognostic (1.61e-1)" "unprognostic (7.22e-3)" "unprognostic (2.90e-1)" "unprognostic (1.65e-1)" "unprognostic (1.48e-3)" "unprognostic (1.28e-3)" "potential prognostic favorable (1.50e-4)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (8.07e-3)" "unprognostic (1.08e-2)" "unprognostic (1.29e-1)" "unprognostic (2.83e-1)" "unprognostic (3.22e-1)" "unprognostic (8.55e-2)" "unprognostic (2.53e-2)" "unprognostic (7.99e-3)" "unprognostic (1.61e-1)" "unprognostic (3.45e-2)" "unprognostic (5.25e-2)" "unprognostic (6.35e-2)" "unprognostic (5.03e-2)" "unprognostic (6.16e-2)" "unprognostic (3.45e-1)" "unprognostic (2.08e-2)" "unprognostic (8.20e-3)" BARD1 ENSG00000138376 "BRCA1 associated RING domain 1" Q99728 2 214725646-214809683 "Cancer-related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 148.4;Monocyte progenitors: 166.3;Neutrophil progenitors: 168.1;Suprabasal keratinocytes: 140.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 740 "Granulosa cells: 105060.4;Oocytes: 43035.2" "Not detected" "Not detected" "CAB034106, HPA035354, HPA044864" Enhanced Supported "Nucleoplasm,Nuclear speckles,Cytoplasmic bodies" No Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 102 "Nucleoplasm, Nuclear speckles" "Cytoplasmic bodies" "CAB034106: , HPA035354: , HPA044864: " "unprognostic (6.83e-3)" "unprognostic (2.35e-1)" "unprognostic (1.62e-1)" "unprognostic (2.37e-1)" "unprognostic (1.74e-2)" "unprognostic (4.37e-2)" "unprognostic (3.74e-2)" "unprognostic (9.99e-2)" "unprognostic (3.66e-3)" "unprognostic (3.26e-2)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (8.62e-2)" "unprognostic (1.93e-3)" "unprognostic (1.93e-3)" "potential prognostic favorable (9.55e-4)" "unprognostic (1.62e-1)" "unprognostic (9.38e-2)" "unprognostic (3.91e-1)" "unprognostic (1.09e-2)" "unprognostic (4.83e-2)" "unprognostic (3.60e-2)" "unprognostic (6.54e-2)" "unprognostic (3.86e-2)" "unprognostic (1.99e-2)" "unprognostic (2.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.63e-1)" "unprognostic (1.77e-2)" BBS1 FLJ23590 ENSG00000174483 "Bardet-Biedl syndrome 1" Q8NFJ9 11 66510606-66533613 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Olfaction, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Astrocytes: 35.8;Bergmann glia: 41.5;Brain excitatory neurons: 35.2;Brain inhibitory neurons: 37.7;Choroid plexus epithelial cells: 51.0;Ependymal cells: 65.3;Microglia: 20.7;Oligodendrocyte progenitor cells: 20.4;Oligodendrocytes: 18.4;Other brain neurons: 32.7" "Group enriched" "Detected in some" 23 "Ciliated cells: 65.3;Glial cells: 41.5;Neuronal cells: 37.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 10338983.6" "Tissue enhanced" "Detected in some" "fallopian tube: 559979.1" HPA058283 Uncertain Uncertain Midbody Yes NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 24: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 35 Midbody "HPA058283: " "unprognostic (9.17e-2)" "unprognostic (9.33e-2)" "unprognostic (4.09e-1)" "unprognostic (2.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.47e-1)" "unprognostic (9.38e-2)" "unprognostic (1.12e-1)" "unprognostic (7.85e-2)" "unprognostic (6.01e-2)" "potential prognostic favorable (7.01e-10)" "unprognostic (1.68e-3)" "potential prognostic favorable (7.69e-4)" "unprognostic (1.30e-1)" "unprognostic (3.50e-2)" "unprognostic (8.12e-2)" "unprognostic (3.86e-2)" "unprognostic (2.77e-2)" "unprognostic (1.60e-1)" "unprognostic (6.34e-2)" "unprognostic (1.81e-1)" "unprognostic (1.95e-1)" "unprognostic (5.10e-2)" "unprognostic (1.16e-1)" "unprognostic (8.54e-2)" "unprognostic (1.52e-1)" "unprognostic (3.25e-2)" "unprognostic (9.13e-2)" "unprognostic (2.05e-1)" "unprognostic (3.33e-1)" "unprognostic (7.71e-2)" BBS4 ENSG00000140463 "Bardet-Biedl syndrome 4" Q96RK4 15 72686179-72738475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 151.1;Early primary spermatocytes: 122.1;Rod photoreceptor cells: 142.5;Thyrotrophs: 130.1" "Cell type enhanced" "Detected in many" "Neuronal cells: 151.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 2960636.0;Pancreatic islets: 5277737.1" "Tissue enriched" "Detected in some" "fallopian tube: 26642.3" HPA039418 Approved Approved "Cytosol,Acrosome,Perinuclear theca,Flagellar centriole,Principal piece,Annulus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 36 "Cytosol, Flagellar centriole, Principal piece" "Acrosome, Perinuclear theca, Annulus" "HPA039418: " "unprognostic (1.31e-1)" "unprognostic (1.12e-1)" "unprognostic (7.74e-2)" "unprognostic (4.93e-2)" "unprognostic (4.00e-1)" "unprognostic (1.92e-1)" "unprognostic (3.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (2.14e-1)" "unprognostic (4.82e-3)" "unprognostic (1.70e-3)" "unprognostic (8.80e-3)" "unprognostic (1.68e-1)" "unprognostic (9.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.77e-1)" "unprognostic (9.58e-3)" "unprognostic (3.84e-1)" "unprognostic (9.81e-2)" "unprognostic (2.00e-3)" "unprognostic (6.99e-3)" "unprognostic (1.27e-1)" "unprognostic (2.10e-1)" "unprognostic (3.97e-1)" "unprognostic (7.46e-2)" "unprognostic (1.90e-1)" "unprognostic (1.44e-1)" "unprognostic (7.05e-2)" "unprognostic (1.84e-2)" BBS5 DKFZp762I194 ENSG00000163093 "Bardet-Biedl syndrome 5" Q8N3I7 2 169479480-169506655 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 31.9;Bergmann glia: 34.7;Brain excitatory neurons: 41.2;Brain inhibitory neurons: 41.7;Choroid plexus epithelial cells: 60.1;Early spermatids: 172.8;Ependymal cells: 129.1;Late primary spermatocytes: 248.6;Late spermatids: 33.0;Oligodendrocyte progenitor cells: 25.3;Oligodendrocytes: 26.8;Other brain neurons: 38.0" "Group enriched" "Detected in some" 4 "Ciliated cells: 129.1;Spermatogenic cell types: 248.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 1559253.0" "Tissue enriched" "Detected in single" 7521 "fallopian tube: 752141.3" HPA046125 Uncertain Supported "Primary cilium,Basal body,Cytosol,Acrosome,Perinuclear theca" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 26 "Basal body, Cytosol, Acrosome" "Primary cilium, Perinuclear theca" "HPA046125: " "unprognostic (2.45e-1)" "unprognostic (3.77e-3)" "unprognostic (2.56e-2)" "unprognostic (5.21e-2)" "unprognostic (8.30e-2)" "unprognostic (6.46e-3)" "unprognostic (4.50e-2)" "unprognostic (9.22e-2)" "unprognostic (2.73e-1)" "unprognostic (9.99e-2)" "unprognostic (1.75e-3)" "unprognostic (2.74e-2)" "unprognostic (1.22e-1)" "unprognostic (1.32e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (7.00e-2)" "unprognostic (2.95e-1)" "unprognostic (1.81e-1)" "unprognostic (1.20e-2)" "unprognostic (1.07e-1)" "unprognostic (1.55e-1)" "unprognostic (5.15e-3)" "unprognostic (7.54e-3)" "unprognostic (3.05e-1)" "unprognostic (5.90e-2)" "unprognostic (2.15e-3)" "unprognostic (1.77e-2)" "unprognostic (2.95e-1)" "unprognostic (2.21e-1)" "unprognostic (9.60e-2)" "unprognostic (6.11e-2)" BBS9 "B1, PTHB1" ENSG00000122507 "Bardet-Biedl syndrome 9" Q3SYG4 7 33109557-33877180 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Sensory transduction, Transport, Vision" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 908.0;Ependymal cells: 962.2;Lactotrophs: 1852.4;Respiratory ciliated cells: 858.3;Rod photoreceptor cells: 1440.7;Somatotrophs: 1336.9;Thyrotrophs: 1421.0" "Cell type enhanced" "Detected in all" "Ciliated cells: 962.2;Neuronal cells: 1440.7;Pituitary endocrine cells: 1852.4" "Cell type enhanced" "Detected in all" "endothelial cell: 1945.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 2395156.6" "Group enriched" "Detected in some" "cerebral cortex: 275998.8;fallopian tube: 511718.9" HPA021289 Uncertain Supported "Nucleoplasm,Vesicles,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol,Acrosome,Equatorial segment,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 67: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 18 "Primary cilium, Primary cilium tip, Primary cilium transition zone, Flagellar centriole, Mid piece, Principal piece" "Nucleoplasm, Vesicles, Cytosol, Acrosome, Equatorial segment" "HPA021289: " "unprognostic (2.10e-1)" "unprognostic (9.91e-3)" "unprognostic (2.04e-3)" "unprognostic (2.80e-1)" "unprognostic (1.72e-1)" "unprognostic (4.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.04e-2)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (8.80e-4)" "potential prognostic favorable (7.35e-5)" "unprognostic (2.63e-2)" "unprognostic (1.05e-2)" "unprognostic (2.71e-3)" "unprognostic (6.51e-2)" "unprognostic (7.25e-2)" "unprognostic (2.35e-2)" "unprognostic (1.59e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (5.02e-2)" "unprognostic (2.09e-1)" "unprognostic (1.42e-2)" "unprognostic (2.50e-2)" "unprognostic (2.18e-2)" "unprognostic (9.03e-3)" "unprognostic (4.71e-1)" "unprognostic (7.77e-2)" "unprognostic (2.42e-1)" "unprognostic (3.29e-1)" "unprognostic (3.10e-2)" BCAS1 "AIBC1, NABC1, PMES-2" ENSG00000064787 "Brain enriched myelin associated protein 1" O75363 20 53936777-54070594 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 201.8;choroid plexus: 83.2;stomach 1: 150.9" "Cell type enhanced" "Detected in many" "Foveolar cells: 1033.2;Goblet cells: 1262.8;Oligodendrocyte progenitor cells: 741.3;Oligodendrocytes: 1972.2;Prostatic club cells: 347.2;Prostatic glandular cells: 348.0;Prostatic hillock cells: 316.5;Urothelial cells: 324.9" "Group enriched" "Detected in many" 4 "Gastric glandular cells: 1033.2;Glial cells: 1972.2;Goblet cells: 1262.8" "Cell type enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 6115.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.7" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "breast cancer: 48.9" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 30877398.8;Microglia and Neuropil: 8321080.7" "Tissue enriched" "Detected in some" "cerebral cortex: 122921829.4" "CAB033558, HPA051816, HPA054745" Enhanced Approved Vesicles NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 3 Vesicles "CAB033558: , HPA051816: , HPA054745: " "potential prognostic favorable (2.20e-4)" "unprognostic (3.83e-2)" "unprognostic (2.96e-2)" "unprognostic (1.98e-1)" "unprognostic (4.80e-2)" "unprognostic (1.93e-1)" "unprognostic (9.59e-2)" "unprognostic (5.42e-2)" "unprognostic (5.63e-2)" "unprognostic (4.18e-3)" "unprognostic (2.65e-2)" "unprognostic (5.64e-2)" "unprognostic (1.38e-1)" "unprognostic (3.06e-1)" "unprognostic (1.23e-1)" "unprognostic (1.30e-2)" "unprognostic (1.57e-1)" "unprognostic (7.18e-2)" "unprognostic (1.48e-2)" "unprognostic (3.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.05e-2)" "unprognostic (3.31e-1)" "unprognostic (2.49e-1)" "unprognostic (8.70e-2)" BCCIP "BCCIPalpha, TOK-1" ENSG00000107949 "BRCA2 and CDKN1A interacting protein" Q9P287 10 125823546-125853695 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "skin: 9817497.4" HPA038011 Approved Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 31 Nucleoplasm Cytosol "HPA038011: " "unprognostic (2.11e-2)" "unprognostic (1.76e-2)" "unprognostic (4.11e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-3)" "unprognostic (1.84e-1)" "unprognostic (1.86e-1)" "unprognostic (1.59e-3)" "potential prognostic unfavorable (8.06e-4)" "potential prognostic unfavorable (5.07e-5)" "potential prognostic favorable (4.07e-4)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (5.65e-4)" "potential prognostic unfavorable (4.24e-5)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (4.66e-5)" "unprognostic (6.45e-2)" "unprognostic (2.94e-2)" "unprognostic (6.05e-2)" "unprognostic (5.19e-2)" "unprognostic (6.35e-3)" "unprognostic (8.63e-3)" "unprognostic (9.70e-3)" "unprognostic (2.03e-3)" "unprognostic (1.14e-1)" "unprognostic (1.13e-1)" "unprognostic (4.74e-2)" "unprognostic (1.00e-1)" "unprognostic (5.28e-2)" "unprognostic (3.63e-1)" "unprognostic (3.76e-2)" BCKDHB ENSG00000083123 "Branched chain keto acid dehydrogenase E1 subunit beta" P21953 6 80106647-80346270 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 73.2" "Cell type enhanced" "Detected in all" "Bergmann glia: 486.7;Pituitary stem cells: 429.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 1725028.1" "Tissue enhanced" "Detected in many" "ovary: 1385498.1" "HPA031580, HPA031956" Approved Supported Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 5 Mitochondria "Nucleoplasm, Nucleoli" "HPA031580: , HPA031956: " "potential prognostic favorable (7.56e-4)" "unprognostic (2.45e-1)" "unprognostic (2.22e-3)" "unprognostic (8.04e-2)" "unprognostic (5.99e-2)" "unprognostic (1.89e-2)" "unprognostic (1.86e-1)" "unprognostic (4.43e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (6.12e-4)" "potential prognostic favorable (7.45e-8)" "unprognostic (7.74e-3)" "unprognostic (3.61e-2)" "unprognostic (1.43e-2)" "unprognostic (4.88e-2)" "unprognostic (7.29e-2)" "unprognostic (3.50e-2)" "unprognostic (2.30e-1)" "unprognostic (3.08e-2)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (2.45e-1)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (2.29e-4)" "unprognostic (9.35e-2)" "unprognostic (1.46e-1)" "unprognostic (2.53e-2)" "unprognostic (1.43e-1)" "unprognostic (9.71e-3)" "unprognostic (1.83e-1)" BCL10 "c-E10, CARMEN, CIPER, CLAP, mE10" ENSG00000142867 "BCL10 immune signaling adaptor" O95999 1 85265776-85276632 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 214.1;Endometrial glandular cells: 197.8;Endometrial secretory cells: 214.2;Esophageal apical cells: 405.7;Fallopian secretory cells: 215.5;Ocular epithelial cells: 249.0;Suprabasal keratinocytes: 190.1;Urothelial cells: 223.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 405.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 2322156.4;T-cells: 1991125.9" "Tissue enhanced" "Detected in many" "skin: 1539998.2" "CAB001944, HPA017925, HPA018953" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 100: Stratified epithelial cells - Barrier functions" 38 Cytosol Nucleoplasm "CAB001944: , HPA017925: , HPA018953: " "unprognostic (3.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.96e-1)" "unprognostic (7.24e-3)" "potential prognostic favorable (4.80e-5)" "unprognostic (4.68e-3)" "unprognostic (3.84e-2)" "unprognostic (1.95e-2)" "unprognostic (2.27e-2)" "unprognostic (1.10e-2)" "validated prognostic favorable (1.52e-10)" "validated prognostic favorable (8.72e-4)" "unprognostic (6.24e-2)" "potential prognostic unfavorable (3.38e-5)" "unprognostic (2.86e-2)" "unprognostic (1.24e-1)" "unprognostic (1.12e-2)" "unprognostic (5.48e-2)" "unprognostic (2.43e-1)" "unprognostic (1.39e-1)" "unprognostic (2.78e-1)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (2.04e-1)" "unprognostic (4.64e-2)" "unprognostic (2.74e-1)" "unprognostic (7.99e-2)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (3.59e-2)" "unprognostic (4.23e-1)" BCL2L1 "Bcl-X, bcl-xL, bcl-xS, BCL2L, BCLX, PPP1R52" ENSG00000171552 "BCL2 like 1" Q07817 20 31664452-31723989 "Cancer-related genes, Essential proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Apoptosis, Endocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 389.3;Esophageal apical cells: 415.4;Platelets: 420.3" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 299.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 4737823.5" "Low tissue specificity" "Detected in all" "HPA035734, CAB072801" Approved Approved "Nucleoli fibrillar center,Mitochondria,Acrosome" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 83 Mitochondria "Nucleoli fibrillar center, Acrosome" "CAB072801: , HPA035734: " "unprognostic (1.35e-2)" "unprognostic (3.28e-1)" "unprognostic (2.94e-2)" "unprognostic (1.07e-2)" "unprognostic (2.66e-1)" "unprognostic (3.79e-2)" "unprognostic (1.60e-1)" "unprognostic (7.25e-3)" "unprognostic (1.85e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (4.09e-6)" "unprognostic (1.52e-2)" "unprognostic (2.58e-3)" "unprognostic (2.83e-2)" "unprognostic (6.21e-2)" "unprognostic (3.06e-3)" "unprognostic (4.37e-2)" "unprognostic (2.23e-2)" "unprognostic (9.20e-2)" "unprognostic (4.57e-2)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (6.21e-2)" "unprognostic (4.35e-2)" "unprognostic (6.13e-2)" "unprognostic (5.68e-3)" "unprognostic (1.38e-1)" "unprognostic (1.28e-1)" "unprognostic (1.58e-1)" "unprognostic (1.38e-2)" "unprognostic (2.29e-1)" BCL3 "BCL4, D19S37" ENSG00000069399 "BCL3 transcription coactivator" P20749 19 44747705-44760044 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.5" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 163.4;Breast secretory cells: 131.1;Neutrophils: 368.1" "Cell type enhanced" "Detected in many" "Neutrophils: 368.1" "Cell type enhanced" "Detected in many" "endothelial cell: 13.5;leukocyte: 9.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 5.5;neutrophil: 19.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 19.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4594 "B-cells: 449474.0;Macrophages: 459359.9;T-cells: 469390.6" "Tissue enriched" "Detected in some" 2 "lymphoid tissue: 29728980.6" "CAB002051, HPA047514" Approved Supported "Nucleoplasm,Vesicles,Midbody,Primary cilium,Basal body,Cytosol" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 25 Nucleoplasm "Vesicles, Midbody, Primary cilium, Basal body, Cytosol" "CAB002051: , HPA047514: " "unprognostic (1.01e-1)" "unprognostic (2.29e-3)" "unprognostic (1.66e-2)" "unprognostic (2.81e-1)" "unprognostic (4.12e-3)" "unprognostic (1.85e-1)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (2.47e-4)" "unprognostic (2.42e-2)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (2.13e-6)" "unprognostic (2.65e-2)" "unprognostic (5.10e-2)" "unprognostic (1.67e-3)" "unprognostic (2.57e-2)" "unprognostic (6.02e-2)" "unprognostic (4.67e-3)" "unprognostic (7.25e-2)" "unprognostic (1.57e-1)" "unprognostic (1.34e-2)" "unprognostic (6.66e-2)" "unprognostic (9.51e-2)" "unprognostic (5.90e-2)" "unprognostic (3.97e-1)" "unprognostic (7.91e-2)" "unprognostic (6.02e-2)" "unprognostic (1.14e-1)" "unprognostic (9.89e-2)" "unprognostic (4.15e-2)" "unprognostic (5.28e-3)" "unprognostic (6.86e-2)" BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Lymphatic endothelial cells: 28.9;Vascular endothelial cells: 39.9" "Cell type enriched" "Detected in some" 14 "Endothelial cells: 39.9" "Cell type enriched" "Detected in some" 23 "endothelial cell: 24.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 26.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3;ovarian cancer: 3.2" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 2 Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: , HPA075112: " "unprognostic (8.41e-2)" "unprognostic (1.63e-2)" "unprognostic (1.01e-2)" "unprognostic (6.91e-2)" "unprognostic (2.15e-3)" "unprognostic (1.12e-1)" "unprognostic (1.25e-1)" "unprognostic (5.68e-1)" "potential prognostic favorable (9.41e-4)" "unprognostic (2.82e-1)" "validated prognostic favorable (1.84e-5)" "validated prognostic favorable (3.36e-4)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (4.08e-2)" "unprognostic (4.82e-3)" "unprognostic (1.56e-1)" "unprognostic (1.60e-2)" "unprognostic (4.56e-2)" "unprognostic (1.32e-1)" "unprognostic (2.26e-1)" "unprognostic (2.69e-1)" "unprognostic (6.78e-2)" "unprognostic (9.11e-2)" "unprognostic (1.22e-1)" "unprognostic (1.60e-2)" "unprognostic (4.58e-1)" "unprognostic (5.12e-3)" "unprognostic (2.55e-2)" "unprognostic (2.81e-1)" "unprognostic (1.37e-2)" "unprognostic (2.11e-1)" BCL9 ENSG00000116128 "BCL9 transcription coactivator" O00512 1 147541501-147626216 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 90.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Fallopian tube cells: 1004111.8;Oocytes: 401007.4" "Tissue enriched" "Detected in some" "pancreas: 269748.5" HPA020274 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 16 "Nucleoplasm, Nuclear bodies" Cytosol "HPA020274: " "unprognostic (1.90e-3)" "unprognostic (7.47e-2)" "unprognostic (2.83e-2)" "unprognostic (2.27e-3)" "unprognostic (2.30e-1)" "unprognostic (1.50e-1)" "unprognostic (2.61e-1)" "unprognostic (6.73e-2)" "unprognostic (2.36e-1)" "unprognostic (2.60e-1)" "potential prognostic favorable (3.61e-4)" "unprognostic (5.00e-2)" "unprognostic (6.70e-3)" "unprognostic (1.39e-3)" "unprognostic (1.36e-1)" "unprognostic (1.06e-2)" "unprognostic (3.60e-2)" "unprognostic (1.01e-1)" "unprognostic (4.82e-2)" "unprognostic (3.69e-2)" "unprognostic (4.94e-2)" "unprognostic (2.79e-2)" "unprognostic (8.41e-2)" "unprognostic (1.48e-1)" "unprognostic (1.76e-2)" "unprognostic (2.13e-1)" "unprognostic (2.75e-2)" "unprognostic (2.52e-1)" "unprognostic (1.17e-1)" "unprognostic (8.54e-2)" "unprognostic (5.32e-2)" BCO1 "BCDO, BCDO1, BCMO, BCMO1, FLJ10730" ENSG00000135697 "Beta-carotene oxygenase 1" Q9HAY6 16 81238689-81291142 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 11.5;intestine: 13.7" "Cell type enriched" "Detected in many" 13 "Retinal pigment epithelial cells: 375.1" "Cell type enriched" "Detected in many" 13 "Pigment cells: 375.1" "Cell type enhanced" "Detected in many" "hippocampal CA4: 71.1" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 5.8" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Oocytes: 92028.6;Proximal tubules: 136557.5" "Tissue enriched" "Detected in single" 958 "intestine: 95822.7" HPA043811 Approved "Actin filaments,Centriolar satellite" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "Actin filaments, Centriolar satellite" "HPA043811: " "potential prognostic favorable (7.49e-4)" "unprognostic (1.01e-1)" "unprognostic (6.79e-2)" "unprognostic (8.16e-3)" "unprognostic (1.06e-1)" "unprognostic (2.12e-3)" "unprognostic (2.17e-1)" "unprognostic (6.37e-2)" "unprognostic (5.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.06e-2)" "unprognostic (7.24e-2)" "unprognostic (1.86e-1)" "unprognostic (2.12e-1)" "unprognostic (9.06e-2)" "unprognostic (1.43e-2)" BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 261.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "skin: 16326214.5" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 52 "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: , CAB018545: , HPA038337: " "unprognostic (2.63e-1)" "unprognostic (1.81e-2)" "unprognostic (3.54e-1)" "unprognostic (1.83e-1)" "unprognostic (1.52e-3)" "unprognostic (1.54e-1)" "unprognostic (4.45e-2)" "unprognostic (4.34e-3)" "unprognostic (2.67e-1)" "unprognostic (1.99e-2)" "validated prognostic favorable (5.86e-10)" "validated prognostic favorable (1.46e-4)" "unprognostic (2.28e-2)" "unprognostic (5.63e-2)" "unprognostic (1.62e-2)" "unprognostic (3.00e-1)" "unprognostic (2.55e-3)" "unprognostic (1.21e-1)" "unprognostic (3.05e-1)" "unprognostic (1.94e-2)" "unprognostic (2.02e-1)" "unprognostic (9.93e-3)" "unprognostic (7.16e-2)" "unprognostic (1.17e-1)" "unprognostic (7.89e-3)" "unprognostic (4.82e-2)" "unprognostic (3.17e-1)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (8.40e-2)" "unprognostic (2.17e-1)" BCS1L "BCS, BJS, h-BCS, Hs.6719" ENSG00000074582 "BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone" Q9Y276 2 218658764-218663443 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Chaperone, Hydrolase" "Deafness, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 48.0;Esophageal basal cells: 43.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 61446368.0" "Tissue enhanced" "Detected in many" "heart muscle: 24526224.3" "HPA037700, HPA037701" Supported Uncertain "Vesicles,Mid piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 12 Vesicles "Mid piece" "HPA037700: , HPA037701: " "unprognostic (2.86e-1)" "unprognostic (5.79e-2)" "unprognostic (2.54e-2)" "unprognostic (3.98e-1)" "unprognostic (4.75e-2)" "unprognostic (1.00e-1)" "unprognostic (1.48e-1)" "unprognostic (1.12e-3)" "unprognostic (2.35e-1)" "unprognostic (2.33e-1)" "unprognostic (1.02e-1)" "unprognostic (6.74e-2)" "unprognostic (1.08e-1)" "unprognostic (1.42e-3)" "unprognostic (5.72e-2)" "unprognostic (1.26e-3)" "unprognostic (4.11e-2)" "unprognostic (4.04e-1)" "unprognostic (2.76e-1)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (2.93e-2)" "unprognostic (6.83e-2)" "unprognostic (2.60e-2)" "unprognostic (3.03e-1)" "unprognostic (3.64e-3)" "unprognostic (9.30e-2)" "unprognostic (2.80e-2)" "unprognostic (2.02e-1)" "unprognostic (3.27e-1)" "unprognostic (3.73e-2)" BDH1 "BDH, SDR9C1" ENSG00000161267 "3-hydroxybutyrate dehydrogenase 1" Q02338 3 197509783-197573323 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Allosteric enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 302.0" "Cell type enhanced" "Detected in many" "Astrocytes: 47.1;Bergmann glia: 42.8;Brain excitatory neurons: 83.4;Brain inhibitory neurons: 81.1;Choroid plexus epithelial cells: 137.8;Distal convoluted tubule cells: 69.8;Ependymal cells: 41.8;Hepatocytes: 49.5;Loop of henle epithelial cells: 53.8;Oligodendrocyte progenitor cells: 62.4;Other brain neurons: 50.6;Papillary tip epithelial cells: 31.7;Proximal tubule cells: 32.4;Renal collecting duct intercalated cells: 35.4;Renal collecting duct principal cells: 30.9;Renal connecting tubule cells: 52.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 137.8;Ductal cells: 52.1;Glial cells: 62.4;Hepatocytes: 49.5;Neuronal cells: 83.4;Renal nephron cells: 69.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 91.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 202851884.8" "Tissue enhanced" "Detected in all" "liver: 101544787.3" "HPA030947, HPA058709" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 53: Liver - Plasma proteins" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 102: Non-specific - Mixed function" 6 Mitochondria Nucleoplasm "HPA030947: , HPA058709: " "unprognostic (4.97e-1)" "unprognostic (5.25e-3)" "unprognostic (2.18e-1)" "unprognostic (1.02e-2)" "unprognostic (1.71e-1)" "unprognostic (7.36e-3)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (1.41e-1)" "unprognostic (1.67e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "potential prognostic favorable (5.77e-4)" "potential prognostic favorable (1.77e-5)" "unprognostic (1.97e-3)" "unprognostic (2.17e-1)" "unprognostic (3.84e-1)" "unprognostic (2.07e-2)" "unprognostic (5.41e-2)" "unprognostic (3.97e-2)" "unprognostic (5.98e-2)" "unprognostic (1.97e-2)" "unprognostic (2.00e-2)" "unprognostic (7.07e-2)" "unprognostic (2.80e-2)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (1.43e-1)" "unprognostic (1.09e-1)" "unprognostic (1.74e-1)" "unprognostic (5.70e-2)" "unprognostic (1.48e-1)" BDH2 "DHRS6, FLJ13261, PRO20933, SDR15C1, UCPA-OR, UNQ6308" ENSG00000164039 "3-hydroxybutyrate dehydrogenase 2" Q9BUT1 4 103077592-103099870 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 145.9" "Cell type enhanced" "Detected in many" "Enterocytes: 77.5;Epididymal efferent duct absorptive cells: 77.9;Retinal pigment epithelial cells: 68.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 228521973.8;Proximal tubules: 333559750.2" "Tissue enhanced" "Detected in all" "kidney: 127331664.3" "HPA036028, HPA036029" Enhanced Supported Cytosol NA NA 16000 "Cluster 24: Non-specific - Transcription" "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 108: Fibroblasts - ECM organization" 1 Cytosol "HPA036028: , HPA036029: " "unprognostic (1.38e-1)" "unprognostic (3.11e-1)" "unprognostic (4.34e-2)" "unprognostic (8.87e-2)" "unprognostic (1.10e-1)" "unprognostic (4.94e-2)" "unprognostic (2.07e-1)" "unprognostic (2.19e-1)" "unprognostic (2.21e-1)" "unprognostic (2.90e-3)" "validated prognostic favorable (2.02e-14)" "validated prognostic favorable (6.26e-6)" "potential prognostic favorable (1.66e-6)" "unprognostic (1.39e-1)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.20e-2)" "unprognostic (3.12e-1)" "unprognostic (2.84e-1)" "unprognostic (2.08e-1)" "unprognostic (4.03e-1)" "unprognostic (3.04e-2)" "unprognostic (4.61e-2)" "unprognostic (2.11e-1)" "unprognostic (5.75e-2)" "unprognostic (4.03e-2)" "unprognostic (9.26e-2)" "unprognostic (4.22e-2)" "unprognostic (1.97e-2)" "unprognostic (2.78e-1)" "unprognostic (4.51e-3)" "unprognostic (5.91e-2)" BEND6 "bA203B9.1, C6orf65, FLJ30162" ENSG00000151917 "BEN domain containing 6" Q5SZJ8 6 56955107-57027346 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 44.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 133.6;Brain inhibitory neurons: 105.8;Oligodendrocyte progenitor cells: 68.9;Other brain neurons: 77.8;Retinal amacrine cells: 80.1;Retinal bipolar cells: 156.7;Retinal ganglion cells: 73.4;Retinal horizontal cells: 58.1" "Cell type enhanced" "Detected in many" "Glial cells: 68.9;Neuronal cells: 156.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 14.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 8.8" "Lineage enriched" "Detected in many" 6 "dendritic cells: 8.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031605, HPA052973" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Plasma membrane" "HPA031605: , HPA052973: " "unprognostic (1.77e-1)" "unprognostic (2.71e-1)" "unprognostic (2.30e-1)" "unprognostic (1.19e-1)" "unprognostic (4.02e-3)" "unprognostic (3.70e-1)" "unprognostic (3.60e-1)" "unprognostic (2.75e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (4.29e-5)" "unprognostic (2.65e-3)" "unprognostic (1.34e-1)" "validated prognostic unfavorable (7.60e-4)" "validated prognostic unfavorable (3.90e-4)" "unprognostic (9.23e-2)" "unprognostic (1.24e-1)" "unprognostic (1.41e-1)" "unprognostic (2.85e-2)" "unprognostic (1.61e-2)" "unprognostic (1.17e-1)" "unprognostic (3.75e-2)" "unprognostic (5.33e-2)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (9.60e-2)" "unprognostic (5.51e-2)" "unprognostic (3.38e-3)" BEND7 "C10orf30, FLJ40283" ENSG00000165626 "BEN domain containing 7" Q8N7W2 10 13438484-13529014 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 254.6;Epididymal efferent duct absorptive cells: 230.9;Late spermatids: 512.3;Pituitary stem cells: 229.5" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 512.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal tubules: 198826.1;Fallopian tube cells: 346505.8" "Tissue enriched" "Detected in some" "skeletal muscle: 286556.6" HPA037835 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles" Yes No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 8 "Nucleoplasm, Nucleoli fibrillar center" Vesicles "HPA037835: " "unprognostic (8.85e-2)" "unprognostic (8.39e-2)" "unprognostic (1.09e-2)" "unprognostic (1.85e-1)" "unprognostic (2.76e-1)" "unprognostic (1.84e-1)" "unprognostic (5.40e-2)" "potential prognostic favorable (1.04e-5)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (6.48e-2)" "potential prognostic favorable (1.13e-4)" "unprognostic (1.70e-2)" "unprognostic (1.18e-1)" "unprognostic (3.37e-3)" "unprognostic (3.10e-2)" "unprognostic (7.72e-2)" "unprognostic (9.44e-3)" "unprognostic (5.91e-3)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (2.07e-1)" "unprognostic (1.82e-1)" "unprognostic (4.93e-3)" "unprognostic (1.71e-1)" "potential prognostic favorable (3.94e-4)" "unprognostic (4.76e-2)" "unprognostic (6.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (5.21e-2)" "unprognostic (2.44e-2)" BEST2 "FLJ20132, VMD2L1" ENSG00000039987 "Bestrophin 2" Q8NFU1 19 12751702-12758458 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 42.7;skin 1: 16.9" "Cell type enriched" "Detected in some" 21 "Goblet cells: 145.5" "Cell type enriched" "Detected in some" 21 "Goblet cells: 145.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Colon - Colon enterocytes, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA046229 Approved Approved "Flagellar centriole,Principal piece,End piece" NA NA "Cluster 77: Intestine - Digestion" "Cluster 25: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 70: Intestinal goblet cells - Mucin production" 14 "Flagellar centriole, Principal piece, End piece" "HPA046229: " "unprognostic (2.46e-2)" "unprognostic (5.41e-3)" "unprognostic (1.27e-1)" "unprognostic (2.06e-3)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (8.29e-4)" "unprognostic (5.58e-2)" BET1L "GOLIM3, GS15" ENSG00000177951 "Bet1 golgi vesicular membrane trafficking protein like" Q9NYM9 11 167784-207399 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 232.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 232.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "Stomach: 2142235.8" HPA039819 Approved Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 15: Bone marrow - Innate immune response" "Cluster 11: White matter - Signal transduction" "Cluster 63: Non-specific - Protein processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 18 "Golgi apparatus" Nucleoplasm "HPA039819: " "unprognostic (7.90e-3)" "unprognostic (3.81e-2)" "unprognostic (8.16e-3)" "unprognostic (2.29e-2)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "validated prognostic unfavorable (5.86e-4)" "validated prognostic unfavorable (1.77e-4)" "unprognostic (3.23e-1)" "unprognostic (2.06e-2)" "potential prognostic favorable (3.23e-5)" "unprognostic (6.31e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (3.11e-2)" "unprognostic (1.46e-1)" "unprognostic (1.76e-2)" "unprognostic (6.57e-2)" "unprognostic (1.50e-1)" "unprognostic (5.04e-2)" "unprognostic (3.87e-3)" "unprognostic (8.31e-2)" "unprognostic (5.70e-2)" "unprognostic (2.18e-1)" "unprognostic (1.92e-1)" "unprognostic (6.25e-2)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.78e-1)" "unprognostic (9.65e-2)" "unprognostic (2.17e-1)" BEX1 ENSG00000133169 "Brain expressed X-linked 1" Q9HBH7 X 103062651-103064171 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 602.9;pituitary gland: 418.3" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 186.4;Granulosa cells: 733.1;Müller glia: 445.5;Neuroendocrine cells: 150.3;Other brain neurons: 257.0;Pancreatic duct cells: 198.9;Pancreatic islet cells: 533.2;Retinal bipolar cells: 183.0;Retinal horizontal cells: 240.4;Sertoli cells: 259.2" "Cell type enhanced" "Detected in many" "Glial cells: 445.5;Neuronal cells: 257.0;Pancreatic islet cells: 533.2;Reproductive supporting cells: 733.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 236.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 312.9" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045384, HPA078630" Approved Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 13 Cytosol "HPA045384: , HPA078630: " "unprognostic (2.51e-2)" "potential prognostic favorable (3.72e-4)" "unprognostic (3.47e-2)" "unprognostic (4.12e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-3)" "unprognostic (1.45e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (2.16e-5)" "unprognostic (9.22e-2)" "unprognostic (1.33e-2)" "unprognostic (1.93e-1)" "unprognostic (3.36e-2)" "unprognostic (2.00e-1)" "unprognostic (5.18e-3)" "unprognostic (1.98e-1)" "unprognostic (1.64e-1)" "unprognostic (1.55e-2)" "unprognostic (4.31e-1)" "potential prognostic favorable (7.06e-4)" "unprognostic (6.50e-2)" "unprognostic (2.52e-1)" "unprognostic (1.49e-1)" "unprognostic (2.08e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (3.81e-1)" BEX2 DJ79P11.1 ENSG00000133134 "Brain expressed X-linked 2" Q9BXY8 X 103309346-103311007 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 301.2;pituitary gland: 199.0" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 417.5;Epididymal efferent duct absorptive cells: 320.2;Epididymal principal cells: 239.1;Müller glia: 203.2;Pancreatic islet cells: 220.9" "Cell type enhanced" "Detected in many" "Basal cells: 417.5;Ductal cells: 320.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 135.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 52.9;NK-cells: 62.2;T-cells: 68.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045384, HPA078630" Uncertain Uncertain Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 22: Epididymis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 73 Cytosol "HPA045384: , HPA078630: " "unprognostic (1.34e-2)" "unprognostic (4.35e-2)" "unprognostic (9.87e-3)" "unprognostic (2.86e-1)" "unprognostic (7.71e-3)" "unprognostic (6.24e-2)" "unprognostic (1.47e-1)" "unprognostic (2.71e-1)" "unprognostic (1.97e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (2.98e-7)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.03e-7)" "unprognostic (1.85e-2)" "unprognostic (6.35e-2)" "unprognostic (4.21e-3)" "unprognostic (7.01e-2)" "unprognostic (2.22e-2)" "unprognostic (8.16e-2)" "unprognostic (1.11e-1)" "unprognostic (1.69e-1)" "unprognostic (7.12e-3)" "unprognostic (6.40e-3)" "unprognostic (7.00e-2)" "unprognostic (1.45e-1)" "unprognostic (3.83e-2)" "unprognostic (2.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.19e-2)" "unprognostic (2.74e-1)" "unprognostic (5.57e-2)" BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 21.1;Alveolar cells type 2: 16.8;Cardiomyocytes: 12.5;Transitional alveolar cells: 16.6;Undifferentiated spermatogonia: 29.2" "Cell type enhanced" "Detected in many" "Alveolar cells: 21.1;Spermatogenic cell types: 29.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 3.2;cerebral cortex: 4.0;hippocampal formation: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 1: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 33: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 81: Alveolar cells - Lung function" 7 "Plasma membrane, Cytosol" "HPA040748: , HPA042038: " "unprognostic (9.03e-3)" "potential prognostic unfavorable (9.99e-5)" "unprognostic (1.03e-1)" "unprognostic (8.38e-2)" "unprognostic (1.09e-1)" "unprognostic (4.68e-2)" "unprognostic (2.82e-1)" "unprognostic (8.15e-2)" "unprognostic (2.29e-1)" "unprognostic (1.71e-1)" "unprognostic (7.26e-2)" "unprognostic (1.71e-3)" "unprognostic (1.39e-1)" "unprognostic (4.74e-2)" "unprognostic (4.97e-2)" "unprognostic (2.26e-1)" "unprognostic (2.83e-1)" "unprognostic (3.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.42e-1)" "unprognostic (5.20e-3)" "unprognostic (2.58e-2)" "unprognostic (5.14e-2)" "unprognostic (5.44e-2)" "unprognostic (1.54e-2)" "unprognostic (3.81e-2)" BHMT BHMT1 ENSG00000145692 "Betaine--homocysteine S-methyltransferase" Q93088 5 79111809-79132288 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 80 "kidney: 727.4;liver: 1067.7" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 77.5;Hepatocytes: 934.5;Proximal tubule cells: 420.8;Urothelial cells: 178.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 178.9;Hepatocytes: 934.5;Renal nephron cells: 420.8" "Cell type enriched" "Detected in many" 19 "hippocampal CA4: 58.5" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 160.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 44.7;Liver Hepatocellular Carcinoma (TCGA): 167.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 4.2;Kidney cancer: 1.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "Glomeruli: 1549031330.4;Hepatocytes: 1194565106.8;Proximal tubules: 2235446082.8" "Tissue enriched" "Detected in many" "liver: 1976719311.2" "HPA038285, HPA058310" Enhanced Approved Cytosol No NA 15000000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 88: Proximal tubular cells - Transmembrane transport" Cytosol "HPA038285: , HPA058310: " "unprognostic (1.61e-1)" "unprognostic (2.06e-2)" "validated prognostic favorable (3.94e-8)" "validated prognostic favorable (2.11e-4)" "unprognostic (3.12e-2)" "potential prognostic favorable (8.19e-4)" "unprognostic (1.31e-3)" "unprognostic (9.17e-2)" "unprognostic (3.31e-1)" BICC1 ENSG00000122870 "BicC family RNA binding protein 1" Q9H694 10 58512872-58831435 "Disease related genes, Predicted intracellular proteins" "Developmental protein, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 26.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 1483.0;Distal convoluted tubule cells: 1678.4;Endometrial ciliated cells: 672.8;Fibro-adipogenic progenitors: 1299.2;Leydig cells: 770.2;Loop of henle epithelial cells: 1486.4;Mesothelial cells: 933.6;Myonuclei: 935.6;Pancreatic duct cells: 1492.1;Proximal tubule cells: 1981.2;Renal collecting duct principal cells: 1044.1;Renal connecting tubule cells: 2040.2" "Cell type enhanced" "Detected in many" "Ductal cells: 2040.2;Fibro-adipogenic progenitors: 1299.2;Renal nephron cells: 1981.2" "Cell type enriched" "Detected in all" 5 "fibroblast: 1315.7" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 33.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 64.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "basophil: 6.2" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 68.3" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 4925402.6" "Group enriched" "Detected in some" "fallopian tube: 94304.2;ovary: 191660.3;skeletal muscle: 59572.2" HPA070797 Approved Centrosome,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" Cytosol Centrosome "HPA070797: " "unprognostic (8.93e-2)" "unprognostic (1.73e-1)" "unprognostic (2.58e-1)" "unprognostic (6.92e-3)" "unprognostic (1.05e-1)" "unprognostic (2.07e-1)" "unprognostic (3.73e-3)" "unprognostic (1.49e-2)" "unprognostic (7.07e-2)" "unprognostic (9.56e-2)" "potential prognostic favorable (4.08e-5)" "unprognostic (9.46e-2)" "unprognostic (1.74e-1)" "unprognostic (2.96e-3)" "unprognostic (1.47e-1)" "unprognostic (1.18e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (5.94e-2)" "unprognostic (2.01e-3)" "unprognostic (5.20e-2)" "unprognostic (8.93e-2)" "unprognostic (1.45e-1)" "unprognostic (8.77e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-3)" "unprognostic (2.64e-2)" "unprognostic (4.64e-2)" "unprognostic (7.55e-2)" BICDL2 CCDC64B ENSG00000162069 "BICD family like cargo adaptor 2" A1A5D9 16 3027682-3036944 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 101.5;pancreas: 123.7" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1246.7" "Cell type enriched" "Detected in many" 4 "Apical squamous epithelial cells: 1246.7" "Cell type enhanced" "Detected in many" "lower rhombic lip: 16.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enhanced" "Detected in some" "basal ganglia: 3.7" "Cell type enriched" "Detected in some" "Keratinocytes: 4033067.3" "Not detected" "Not detected" HPA043251 Approved Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 60: Stomach - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Intermediate filaments, Actin filaments, Cytosol" "HPA043251: " "potential prognostic favorable (8.48e-4)" "unprognostic (1.30e-1)" "unprognostic (1.77e-1)" "unprognostic (1.13e-1)" "unprognostic (1.31e-1)" "unprognostic (1.59e-2)" "unprognostic (1.45e-3)" "unprognostic (2.99e-2)" "unprognostic (8.00e-2)" "unprognostic (9.92e-2)" "unprognostic (1.53e-1)" "unprognostic (5.92e-2)" "unprognostic (1.03e-1)" "unprognostic (3.40e-2)" "unprognostic (8.70e-2)" "unprognostic (1.20e-3)" "unprognostic (2.37e-1)" "unprognostic (1.90e-2)" "unprognostic (2.33e-1)" "unprognostic (1.36e-1)" "unprognostic (7.16e-2)" "unprognostic (1.55e-2)" "unprognostic (2.09e-1)" "unprognostic (2.85e-2)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "unprognostic (3.96e-2)" BIRC2 "API1, c-IAP1, cIAP1, hiap-2, MIHB, RNF48" ENSG00000110330 "Baculoviral IAP repeat containing 2" Q13490 11 102347211-102378670 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 242.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Adrenocortical cancer: 319.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 5639682.3;Oocytes: 4380040.1" "Group enriched" "Detected in some" "bone marrow: 1007252.7;salivary gland: 380653.2" "HPA005513, CAB020661" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 131 "Nucleoli fibrillar center, Cytosol" Nucleoplasm "CAB020661: , HPA005513: " "unprognostic (1.60e-1)" "unprognostic (7.44e-2)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (2.83e-1)" "unprognostic (5.18e-2)" "unprognostic (1.78e-1)" "unprognostic (1.96e-1)" "unprognostic (1.52e-1)" "unprognostic (4.57e-2)" "unprognostic (3.28e-3)" "unprognostic (9.14e-3)" "unprognostic (9.06e-2)" "unprognostic (6.81e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (3.78e-5)" "unprognostic (1.93e-2)" "unprognostic (3.50e-1)" "unprognostic (3.01e-2)" "unprognostic (4.83e-1)" "unprognostic (1.40e-1)" "unprognostic (1.79e-2)" "potential prognostic unfavorable (7.24e-5)" "unprognostic (2.91e-2)" "unprognostic (5.09e-3)" "unprognostic (2.93e-2)" "unprognostic (1.86e-2)" "unprognostic (8.57e-2)" "unprognostic (2.89e-1)" "unprognostic (3.09e-1)" "unprognostic (1.25e-2)" BIRC5 "API4, EPR-1, survivin" ENSG00000089685 "Baculoviral IAP repeat containing 5" O15392 17 78214186-78225636 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis, Transcription, Transcription regulation" "Protease inhibitor, Repressor, Thiol protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.8;lymphoid tissue: 38.1;testis: 18.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 83.9;Differentiating spermatogonia: 100.9;Early primary spermatocytes: 111.0;Early spermatids: 75.5;Enteric transient amplifying cells: 105.2;Erythrocyte progenitors: 154.8;Esophageal basal cells: 169.3;Extravillous trophoblasts: 178.1;Gastric progenitor cells: 115.4;Hofbauer cells: 76.9;Late primary spermatocytes: 284.0;Late spermatids: 95.3;Megakaryocyte progenitors: 121.8;Megakaryocytes: 92.7;Migrating cytotrophoblasts: 140.7;Monocyte progenitors: 135.3;Oocytes: 124.3" "Cell type enhanced" "Detected in many" "Basal cells: 169.3;Erythrocytes: 154.8;Megakaryocytes: 121.8;Mononuclear phagocytes: 135.3;Oocytes: 124.3;Spermatogenic cell types: 284.0;Trophoblast cells: 178.1" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 14.1" "Lineage enriched" "Detected in many" 6 "T-cells: 14.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 216 "bone marrow: 21611.4" "HPA002830, CAB004270" Enhanced Supported "Cytokinetic bridge" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 57 "Cytokinetic bridge" "CAB004270: , HPA002830: " "unprognostic (1.18e-2)" "unprognostic (3.64e-2)" "unprognostic (1.37e-1)" "unprognostic (2.55e-1)" "unprognostic (1.82e-2)" "unprognostic (7.15e-2)" "unprognostic (2.36e-1)" "unprognostic (1.03e-1)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (2.00e-5)" "validated prognostic unfavorable (3.12e-10)" "validated prognostic unfavorable (1.21e-7)" "potential prognostic unfavorable (6.21e-12)" "validated prognostic unfavorable (8.71e-6)" "validated prognostic unfavorable (4.42e-10)" "validated prognostic unfavorable (4.12e-5)" "validated prognostic unfavorable (2.52e-4)" "unprognostic (1.10e-1)" "unprognostic (9.49e-3)" "unprognostic (5.22e-2)" "unprognostic (1.04e-3)" "unprognostic (3.02e-3)" "unprognostic (2.80e-2)" "unprognostic (6.62e-2)" "unprognostic (1.35e-1)" "unprognostic (3.72e-3)" "unprognostic (5.51e-2)" "unprognostic (1.57e-2)" "unprognostic (1.74e-1)" "unprognostic (2.61e-2)" "unprognostic (2.84e-1)" BIRC6 BRUCE ENSG00000115760 "Baculoviral IAP repeat containing 6" Q9NR09 2 32357023-32619571 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 9.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 8925973.6" "HPA074409, HPA074738" Approved Supported "Golgi apparatus,Vesicles,Mitotic spindle" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 45 "Golgi apparatus, Vesicles" "Mitotic spindle" "HPA074409: , HPA074738: " "unprognostic (1.98e-1)" "unprognostic (6.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.23e-2)" "unprognostic (6.53e-2)" "unprognostic (2.28e-1)" "unprognostic (1.16e-2)" "unprognostic (5.56e-3)" "unprognostic (4.31e-2)" "unprognostic (3.19e-3)" "potential prognostic favorable (1.98e-6)" "unprognostic (6.24e-3)" "unprognostic (1.69e-1)" "unprognostic (2.77e-1)" "unprognostic (1.47e-1)" "unprognostic (2.22e-1)" "unprognostic (8.68e-3)" "unprognostic (2.77e-2)" "unprognostic (3.61e-1)" "unprognostic (1.79e-2)" "unprognostic (5.70e-2)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (6.11e-4)" "unprognostic (1.17e-1)" "unprognostic (7.54e-3)" "potential prognostic favorable (3.11e-4)" "unprognostic (1.55e-1)" "unprognostic (3.19e-1)" "unprognostic (3.08e-1)" "unprognostic (1.43e-2)" "unprognostic (1.03e-1)" BLCAP BC10 ENSG00000166619 "BLCAP apoptosis inducing factor" P62952 20 37492472-37527931 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 452.1" "Cell type enhanced" "Detected in all" "Adipocytes: 308.6;Late spermatids: 311.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA047390 Approved Nucleoli NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 14 Nucleoli "HPA047390: " "unprognostic (3.82e-2)" "unprognostic (3.78e-2)" "unprognostic (4.06e-1)" "unprognostic (2.68e-2)" "unprognostic (1.54e-3)" "unprognostic (6.50e-2)" "unprognostic (1.36e-1)" "unprognostic (3.48e-3)" "unprognostic (1.60e-3)" "unprognostic (2.08e-1)" "unprognostic (6.97e-3)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (3.59e-1)" "unprognostic (4.24e-1)" "unprognostic (8.13e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-1)" "unprognostic (1.36e-1)" "unprognostic (4.21e-3)" "unprognostic (4.72e-2)" "unprognostic (4.40e-2)" "unprognostic (7.63e-2)" "unprognostic (1.62e-1)" "unprognostic (3.36e-2)" "unprognostic (2.53e-2)" "unprognostic (2.38e-1)" "unprognostic (5.92e-2)" "unprognostic (2.00e-1)" "unprognostic (5.60e-2)" "unprognostic (3.94e-2)" BLK MGC10442 ENSG00000136573 "BLK proto-oncogene, Src family tyrosine kinase" P51451 8 11486894-11564599 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 19 "intestine: 40.2;lymphoid tissue: 49.9" "Cell type enriched" "Detected in some" 15 "B-cells: 165.6" "Cell type enriched" "Detected in some" 15 "B-cells: 165.6" "Cell type enriched" "Detected in some" 26 "leukocyte: 32.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "memory B-cell: 167.9;naive B-cell: 118.0" "Lineage enriched" "Detected in many" 5 "B-cells: 167.9" "Cancer enriched" "Detected in some" 4 "lymphoma: 64.1" "Lung - B-cells (Lung), Minor Salivary Gland - Plasma cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "B-cells: 5104417.6;T-cells: 1663162.0" "Tissue enriched" "Detected in some" "lymphoid tissue: 483801.1" "CAB005093, HPA069571" Approved Uncertain Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 42 Nucleoplasm "CAB005093: , HPA069571: " "unprognostic (6.08e-3)" "unprognostic (3.42e-1)" "unprognostic (1.66e-3)" "unprognostic (8.21e-2)" "unprognostic (1.15e-1)" "unprognostic (2.65e-2)" "unprognostic (4.65e-2)" BLMH BH ENSG00000108578 "Bleomycin hydrolase" Q13867 17 30248203-30292056 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 128.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Keratinocytes: 50817472.6" "Low tissue specificity" "Detected in all" "HPA039548, HPA064307" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 22000000 "Cluster 11: T-cells - Unknown function" "Cluster 9: Skin - Hair follicle development" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 29 "Nucleoplasm, Nuclear bodies, Cytosol" "HPA039548: , HPA064307: " "unprognostic (7.03e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (2.43e-4)" "unprognostic (1.54e-1)" "unprognostic (1.77e-3)" "unprognostic (3.58e-2)" "unprognostic (8.04e-2)" "unprognostic (1.88e-3)" "unprognostic (7.47e-2)" "unprognostic (3.98e-2)" "validated prognostic favorable (4.44e-6)" "validated prognostic favorable (2.28e-4)" "unprognostic (1.41e-1)" "validated prognostic unfavorable (7.17e-4)" "validated prognostic unfavorable (4.49e-4)" "unprognostic (3.73e-2)" "unprognostic (5.00e-1)" "unprognostic (3.00e-2)" "unprognostic (2.76e-3)" "unprognostic (1.48e-2)" "unprognostic (3.56e-1)" "unprognostic (4.19e-3)" "unprognostic (4.43e-2)" "unprognostic (1.42e-1)" "unprognostic (8.85e-2)" "unprognostic (3.22e-3)" "unprognostic (5.66e-3)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" "unprognostic (2.31e-1)" BLTP2 "BCOX, BCOX1, CT101, DKFZp686M0843, FMP27, Hob, KIAA0100, MGC111488" ENSG00000007202 "Bridge-like lipid transfer protein family member 2" Q14667 17 28614446-28645454 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "cerebral cortex: 127923.6;fallopian tube: 142441.4;lymphoid tissue: 123658.2;salivary gland: 41831.3" HPA042781 Uncertain Approved "Nuclear speckles,Cytosol" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 "Nuclear speckles, Cytosol" "HPA042781: " "unprognostic (1.67e-1)" "unprognostic (1.61e-1)" "unprognostic (1.92e-1)" "unprognostic (3.01e-2)" "unprognostic (5.45e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-1)" "unprognostic (1.81e-2)" "unprognostic (4.02e-2)" "unprognostic (1.57e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (1.30e-1)" "unprognostic (1.43e-3)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (3.50e-3)" "unprognostic (1.31e-1)" "unprognostic (3.39e-1)" "unprognostic (2.11e-2)" "unprognostic (7.89e-2)" "unprognostic (1.10e-3)" "unprognostic (2.17e-1)" "unprognostic (1.67e-2)" "unprognostic (8.62e-2)" "unprognostic (2.33e-1)" "unprognostic (1.81e-3)" "unprognostic (1.34e-2)" "unprognostic (1.77e-1)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (7.91e-2)" "unprognostic (2.61e-1)" BLTP3B "KIAA0701, SHIP164, UHRF1BP1L" ENSG00000111647 "Bridge-like lipid transfer protein family member 3B" A0JNW5 12 100028455-100142874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 481.9" "Cell type enhanced" "Detected in all" "Neutrophils: 481.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 2024175.6;Fallopian tube cells: 6315889.8;Macrophages: 2426118.5;Microglia and Neuropil: 4555884.7;Neurons: 6125068.0" "Tissue enhanced" "Detected in many" "kidney: 4672574.2" "HPA039671, HPA075150" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 32 Nucleoplasm "Vesicles, Cytosol" "HPA039671: , HPA075150: " "unprognostic (1.43e-1)" "unprognostic (3.90e-2)" "unprognostic (3.88e-1)" "unprognostic (7.69e-2)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (1.70e-1)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (6.12e-4)" "potential prognostic favorable (2.69e-6)" "unprognostic (2.51e-1)" "unprognostic (2.65e-1)" "unprognostic (1.25e-2)" "unprognostic (8.28e-2)" "unprognostic (6.69e-3)" "unprognostic (1.82e-2)" "unprognostic (7.34e-2)" "unprognostic (3.39e-1)" "unprognostic (3.16e-2)" "unprognostic (3.40e-3)" "unprognostic (7.64e-3)" "unprognostic (1.73e-2)" "unprognostic (1.19e-1)" "unprognostic (2.33e-1)" "unprognostic (3.19e-3)" "unprognostic (3.01e-1)" "unprognostic (8.63e-2)" "unprognostic (3.02e-1)" "unprognostic (7.64e-2)" "unprognostic (2.23e-1)" BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 588.8" "Cell type enhanced" "Detected in many" "Enterocytes: 925.2;Erythrocyte progenitors: 1710.2;Erythrocytes: 921.8;Esophageal apical cells: 3709.2;Hepatocytes: 861.7;Hofbauer cells: 2026.0;Kupffer cells: 873.2" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 3709.2;Erythrocytes: 1710.2;Mononuclear phagocytes: 2026.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 466.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.8;monocytes: 466.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 210000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 15: Bone marrow - Innate immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 84: Apical squamous epithelium - Cornification" 9 Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: , HPA041937: " "unprognostic (2.10e-2)" "unprognostic (6.71e-2)" "unprognostic (1.95e-1)" "potential prognostic favorable (3.06e-4)" "unprognostic (1.66e-1)" "unprognostic (2.95e-3)" "unprognostic (3.66e-3)" "unprognostic (1.81e-1)" "unprognostic (1.33e-1)" "unprognostic (2.59e-2)" "unprognostic (1.06e-3)" "unprognostic (5.50e-2)" "unprognostic (2.61e-2)" "unprognostic (2.36e-1)" "unprognostic (2.09e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (1.27e-1)" "unprognostic (3.31e-2)" "unprognostic (1.05e-1)" "unprognostic (5.15e-2)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (7.61e-5)" "unprognostic (8.66e-2)" "unprognostic (2.79e-1)" "unprognostic (5.16e-1)" "unprognostic (2.11e-1)" "unprognostic (2.99e-1)" "unprognostic (1.67e-1)" "unprognostic (8.85e-3)" "unprognostic (9.67e-3)" "unprognostic (5.01e-2)" BMAL2 "ARNTL2, bHLHe6, CLIF, MOP9, PASD9" ENSG00000029153 "Basic helix-loop-helix ARNT like 2" Q8WYA1 12 27332836-27425289 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 26.1;lymphoid tissue: 20.5" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 195.1;Esophageal apical cells: 717.0;Respiratory basal cells: 233.1;Respiratory deuterosomal cells: 193.8;Respiratory secretory cells: 120.5;Salivary basal cells: 125.7;Suprabasal keratinocytes: 142.8;Urothelial cells: 396.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 717.0;Barrier epithelial cells: 396.1;Basal cells: 233.1" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 205.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2016 "Neurons: 201619.0" "Not detected" "Not detected" HPA059074 Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 81: Squamous epithelium - Keratinization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 "Nucleoplasm, Nucleoli" "HPA059074: " "unprognostic (2.01e-1)" "unprognostic (1.86e-2)" "unprognostic (2.70e-1)" "unprognostic (2.31e-2)" "unprognostic (1.08e-1)" "unprognostic (3.71e-3)" "unprognostic (1.76e-1)" "unprognostic (9.19e-3)" "unprognostic (9.29e-2)" "unprognostic (6.98e-3)" "unprognostic (1.40e-3)" "unprognostic (1.04e-1)" "unprognostic (1.19e-1)" "unprognostic (1.20e-2)" "unprognostic (2.07e-2)" "validated prognostic unfavorable (2.55e-6)" "validated prognostic unfavorable (4.19e-4)" "unprognostic (6.22e-2)" "unprognostic (5.23e-2)" "unprognostic (1.42e-1)" "unprognostic (1.10e-2)" "validated prognostic unfavorable (7.29e-8)" "validated prognostic unfavorable (5.68e-6)" "unprognostic (1.82e-3)" "unprognostic (9.29e-2)" "unprognostic (1.79e-2)" "unprognostic (3.81e-2)" "unprognostic (2.68e-1)" "unprognostic (2.69e-1)" "unprognostic (1.17e-2)" BMP2 BMP2A ENSG00000125845 "Bone morphogenetic protein 2" P12643 20 6767686-6780246 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 193.1;Alveolar cells type 2: 170.1;Basal keratinocytes: 141.7;Colonocytes: 91.0;Epicardial cells: 81.9;Epididymal basal cells: 116.3;Lymphatic endothelial cells: 67.7;Pancreatic duct cells: 92.0;Pericytes: 62.3;Suprabasal keratinocytes: 73.2;Urothelial cells: 171.0" "Cell type enhanced" "Detected in many" "Alveolar cells: 193.1;Barrier epithelial cells: 171.0;Basal cells: 141.7" "Cell type enhanced" "Detected in many" "fibroblast: 41.7;oligodendrocyte precursor cell: 19.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 30.7" "Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 338 "intestine: 33793.8" "HPA049966, HPA058610, CAB078457" Approved "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" "Secreted to blood" Cytokine NA NA 24400 10000 "Cluster 13: Lung - Secretion" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 69: Urothelial cells - Basic cellular functions" 10 Vesicles "Nucleoplasm, Plasma membrane, Primary cilium, Primary cilium tip, Primary cilium transition zone, Basal body, Cytosol" "CAB078457: , HPA049966: , HPA058610: " "unprognostic (4.43e-2)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.47e-1)" "unprognostic (3.70e-2)" "unprognostic (4.88e-2)" "potential prognostic favorable (1.73e-4)" "unprognostic (1.25e-1)" "unprognostic (4.45e-3)" "potential prognostic favorable (1.77e-6)" "unprognostic (1.42e-1)" "unprognostic (1.90e-1)" "unprognostic (2.27e-3)" "unprognostic (8.00e-2)" "unprognostic (3.97e-2)" "unprognostic (5.29e-3)" "unprognostic (1.40e-3)" "unprognostic (1.29e-1)" "unprognostic (5.40e-3)" "unprognostic (3.94e-1)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (1.44e-2)" "unprognostic (7.84e-2)" "unprognostic (1.81e-1)" "unprognostic (5.56e-1)" "unprognostic (3.91e-3)" "unprognostic (7.07e-2)" BMP6 "VGR, VGR1" ENSG00000153162 "Bone morphogenetic protein 6" P22004 6 7726099-7881728 "Predicted secreted proteins" "Chondrogenesis, Differentiation, Osteogenesis" "Cytokine, Developmental protein, Growth factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 19.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 96.0;Hematopoietic stem cells: 125.7;Loop of henle epithelial cells: 110.3;Neutrophils: 156.4;Oocytes: 170.4;Pituitary stem cells: 363.7;Plasma cells: 349.3;Platelets: 343.8;Undifferentiated spermatogonia: 81.3;Vascular endothelial cells: 163.6" "Cell type enhanced" "Detected in many" "Plasma cells: 349.3;Platelets: 343.8;Stem cells: 363.7" "Group enriched" "Detected in many" 4 "endothelial cell: 361.6;fibroblast: 404.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 11 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "Myeloma: 42.2;Rhabdoid: 30.5" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Plasma cells, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002773, HPA062683" Approved Approved Mitochondria "Secreted to blood" Cytokine No No 4970000 57000 "Cluster 46: Basophils - Proteolysis" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 Mitochondria "CAB002773: , HPA062683: " "unprognostic (9.89e-2)" "unprognostic (1.75e-2)" "unprognostic (7.47e-2)" "unprognostic (1.67e-1)" "unprognostic (2.08e-1)" "unprognostic (2.40e-1)" "unprognostic (5.77e-3)" "unprognostic (1.07e-1)" "unprognostic (4.37e-1)" "potential prognostic favorable (7.51e-7)" "unprognostic (6.05e-3)" "unprognostic (1.45e-1)" "unprognostic (1.78e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (8.17e-5)" "unprognostic (5.47e-2)" "unprognostic (2.79e-1)" "unprognostic (4.42e-2)" "unprognostic (2.39e-2)" "unprognostic (4.83e-2)" "unprognostic (1.65e-1)" "unprognostic (2.57e-1)" "unprognostic (2.05e-1)" "unprognostic (2.23e-2)" "unprognostic (1.82e-2)" "unprognostic (6.07e-2)" "unprognostic (1.79e-1)" "unprognostic (1.89e-2)" BMS1 "BMS1L, KIAA0187" ENSG00000165733 "BMS1 ribosome biogenesis factor" Q14692 10 42782795-42834937 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" Hydrolase "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "bone marrow: 4950537.3;Stomach: 2008859.3" "HPA036589, HPA043081" Uncertain Enhanced "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 67 "Nucleoplasm, Nucleoli, Mitotic chromosome" "HPA036589: , HPA043081: " "unprognostic (2.76e-1)" "unprognostic (5.60e-3)" "unprognostic (8.31e-2)" "unprognostic (3.84e-1)" "unprognostic (2.22e-1)" "unprognostic (1.99e-1)" "unprognostic (4.44e-2)" "potential prognostic favorable (7.25e-6)" "unprognostic (2.32e-3)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (1.12e-2)" "unprognostic (5.97e-3)" "unprognostic (7.59e-2)" "potential prognostic unfavorable (1.32e-6)" "unprognostic (8.81e-3)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (7.50e-5)" "unprognostic (3.53e-2)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (3.92e-2)" "unprognostic (7.57e-3)" "unprognostic (2.15e-2)" "unprognostic (1.97e-2)" "unprognostic (1.87e-1)" "unprognostic (2.29e-1)" "unprognostic (6.97e-2)" "unprognostic (1.88e-1)" "unprognostic (2.85e-1)" "unprognostic (1.30e-1)" "unprognostic (7.82e-2)" BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "epididymis: 96.9" "Cell type enriched" "Detected in many" 4 "Tuft cells: 1037.5" "Cell type enriched" "Detected in many" 4 "Secretory gland support: 1037.5" "Cell type enriched" "Detected in many" 4 "endothelial cell: 41.4" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 5.2" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Group enriched" "Detected in some" 6 "cervical cancer: 2.6;lung cancer: 4.6;prostate cancer: 2.0;skin cancer: 1.7" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2, Stomach - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neutrophils: 3194223.3" "Group enriched" "Detected in some" 33 "intestine: 3244.9;lymphoid tissue: 3415.3" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 "Plasma membrane" Nucleoplasm "CAB032495: , HPA001048: " "unprognostic (1.96e-2)" "unprognostic (5.64e-2)" "unprognostic (3.20e-1)" "potential prognostic favorable (4.88e-9)" "unprognostic (1.66e-3)" "unprognostic (1.07e-2)" "unprognostic (2.35e-1)" "unprognostic (1.92e-1)" "unprognostic (2.24e-1)" "unprognostic (9.69e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-1)" "unprognostic (6.53e-2)" "unprognostic (2.23e-1)" "unprognostic (8.62e-2)" "unprognostic (1.75e-1)" BNC1 "BNC, HsT19447" ENSG00000169594 "Basonuclin 1" Q01954 15 83255884-83284664 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 14.2;esophagus: 12.0;testis: 23.6" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 118.7;Early spermatids: 42.0;Epicardial cells: 154.6;Epididymal basal cells: 54.3;Esophageal basal cells: 54.9;Late primary spermatocytes: 52.1;Late spermatids: 180.8;Mesothelial cells: 356.3;Ocular epithelial cells: 71.7;Suprabasal keratinocytes: 71.1" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 356.3;Basal cells: 118.7;Spermatogenic cell types: 180.8;Suprabasal cells: 71.1" "Cell type enhanced" "Detected in some" "pericyte: 1.9" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 19.1;Head and Neck Squamous Cell Carcinoma (TCGA): 37.9;Lung Squamous Cell Carcinoma (TCGA): 13.0;Testicular Germ Cell Tumor (TCGA): 15.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 29.8" "Adipose visceral - Mesothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1096 "Oocytes: 109585.6" "Not detected" "Not detected" "HPA063183, HPA077428" Enhanced Nucleoplasm NA NA "Cluster 39: Testis - Nuclear processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 2 Nucleoplasm "HPA063183: , HPA077428: " "unprognostic (3.74e-2)" "unprognostic (2.65e-1)" "unprognostic (1.58e-1)" "unprognostic (7.72e-2)" "unprognostic (1.93e-2)" "unprognostic (2.45e-1)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (4.01e-2)" "unprognostic (2.45e-1)" "unprognostic (4.19e-3)" BNIP3L "BNIP3a, Nix" ENSG00000104765 "BCL2 interacting protein 3 like" O60238 8 26383054-26505636 "Cancer-related genes, Predicted membrane proteins, Transporters" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 868.3;Erythrocytes: 671.1;Esophageal apical cells: 915.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 915.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 505604.9" "Tissue enhanced" "Detected in many" "cerebral cortex: 4324671.7" "HPA015652, CAB025371" Enhanced Supported "Nuclear speckles,Mitochondria" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 28 Mitochondria "Nuclear speckles" "CAB025371: , HPA015652: " "unprognostic (8.45e-2)" "unprognostic (8.10e-2)" "unprognostic (2.10e-1)" "unprognostic (2.56e-1)" "unprognostic (1.71e-1)" "unprognostic (2.53e-2)" "unprognostic (9.13e-3)" "unprognostic (6.29e-2)" "unprognostic (1.21e-1)" "unprognostic (1.91e-3)" "potential prognostic favorable (8.46e-8)" "unprognostic (1.19e-3)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (3.73e-2)" "unprognostic (1.84e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (2.55e-2)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (5.90e-4)" "unprognostic (1.23e-2)" "unprognostic (2.08e-2)" "unprognostic (2.01e-1)" "unprognostic (3.58e-1)" "unprognostic (2.19e-1)" "unprognostic (1.49e-1)" "unprognostic (7.27e-3)" "unprognostic (4.09e-1)" "unprognostic (2.98e-3)" "unprognostic (1.50e-1)" BOLA3 ENSG00000163170 "BolA family member 3" Q53S33 2 74135400-74147912 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 162.0" "Cell type enhanced" "Detected in all" "Enteric transient amplifying cells: 189.5;Esophageal basal cells: 210.6;Extravillous trophoblasts: 221.5;Parietal cells: 475.6" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 475.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9463 "Collecting ducts: 482193.0;Distal tubules: 1227110.0;Large ducts: 1619114.1;Proximal tubules: 456673.2" "Tissue enhanced" "Detected in many" "heart muscle: 14592176.8" "HPA046393, HPA053162" Uncertain Supported "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 97: Non-specific - Cellular respiration" 11 "Nuclear bodies, Mitochondria" Cytosol "HPA046393: , HPA053162: " "unprognostic (2.93e-2)" "unprognostic (4.03e-2)" "unprognostic (1.12e-1)" "unprognostic (5.52e-2)" "unprognostic (8.27e-2)" "unprognostic (3.94e-2)" "unprognostic (1.83e-2)" "unprognostic (7.66e-3)" "unprognostic (6.58e-3)" "unprognostic (2.72e-3)" "potential prognostic unfavorable (9.14e-5)" "unprognostic (2.82e-3)" "unprognostic (4.88e-2)" "validated prognostic unfavorable (3.56e-4)" "validated prognostic unfavorable (5.94e-10)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (4.27e-1)" "unprognostic (2.81e-2)" "unprognostic (6.29e-2)" "unprognostic (1.07e-2)" "unprognostic (1.55e-1)" "unprognostic (2.33e-2)" "unprognostic (2.24e-2)" "unprognostic (1.08e-1)" "unprognostic (3.37e-1)" "unprognostic (8.66e-2)" "unprognostic (1.63e-2)" "unprognostic (8.33e-2)" "unprognostic (3.89e-1)" "unprognostic (8.21e-2)" "unprognostic (1.82e-1)" BOP1 KIAA0124 ENSG00000261236 "BOP1 ribosomal biogenesis factor" Q14137 8 144262045-144291438 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 69.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 58.6;Esophageal basal cells: 71.9;Esophageal suprabasal cells: 51.9;Pancreatic acinar cells: 50.4;Undifferentiated spermatogonia: 58.0" "Cell type enhanced" "Detected in many" "Basal cells: 71.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "liver: 1999776.0" "HPA047869, HPA066764" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 7100 "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 39 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA047869: , HPA066764: " "unprognostic (1.97e-2)" "unprognostic (1.35e-1)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (1.92e-1)" "unprognostic (4.00e-2)" "unprognostic (1.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (4.96e-5)" "unprognostic (2.82e-2)" "unprognostic (8.17e-3)" "validated prognostic unfavorable (2.97e-5)" "validated prognostic unfavorable (1.06e-4)" "potential prognostic unfavorable (8.62e-4)" "unprognostic (4.65e-3)" "unprognostic (5.96e-2)" "unprognostic (4.13e-1)" "unprognostic (1.82e-2)" "unprognostic (3.14e-3)" "unprognostic (5.19e-2)" "unprognostic (4.22e-2)" "unprognostic (3.40e-2)" "unprognostic (1.97e-1)" "unprognostic (9.76e-2)" "unprognostic (3.23e-1)" "unprognostic (5.82e-2)" "unprognostic (6.10e-2)" BORCS5 "LOH12CR1, LOH1CR12" ENSG00000165714 "BLOC-1 related complex subunit 5" Q969J3 12 12357078-12471233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 57.5;Bergmann glia: 51.0;Brain excitatory neurons: 59.6;Brain inhibitory neurons: 67.9;Choroid plexus epithelial cells: 74.7;Distal convoluted tubule cells: 55.6;Ependymal cells: 54.5;Loop of henle epithelial cells: 39.3;Microglia: 56.3;Oligodendrocyte progenitor cells: 38.2;Oligodendrocytes: 144.1;Other brain neurons: 71.3;Papillary tip epithelial cells: 34.1;Podocytes: 73.0;Proximal tubule cells: 33.8;Renal collecting duct intercalated cells: 40.0;Renal collecting duct principal cells: 43.2;Renal connecting tubule cells: 40.2" "Group enriched" "Detected in many" 6 "Ciliated cells: 74.7;Ductal cells: 43.2;Glial cells: 144.1;Neuronal cells: 71.3;Renal nephron cells: 73.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 1445330.0" "Low tissue specificity" "Detected in all" "HPA039509, HPA043627" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 16 "Vesicles, Plasma membrane" "HPA039509: , HPA043627: " "unprognostic (2.06e-1)" "unprognostic (1.56e-1)" "unprognostic (2.05e-1)" "unprognostic (3.15e-2)" "unprognostic (8.18e-2)" "unprognostic (2.12e-1)" "unprognostic (2.11e-2)" "unprognostic (5.25e-2)" "unprognostic (3.35e-1)" "unprognostic (1.63e-3)" "unprognostic (2.21e-1)" "unprognostic (2.21e-1)" "unprognostic (7.31e-3)" "unprognostic (3.12e-3)" "unprognostic (8.98e-2)" "unprognostic (6.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.62e-1)" "unprognostic (2.18e-1)" "unprognostic (4.96e-2)" "unprognostic (1.70e-2)" "unprognostic (1.43e-1)" "unprognostic (2.06e-1)" "unprognostic (1.88e-2)" "unprognostic (9.50e-2)" "unprognostic (2.15e-1)" "unprognostic (2.84e-1)" "unprognostic (1.05e-2)" "unprognostic (2.23e-1)" BPHL "Bph-rp, MCNAA, VACVase" ENSG00000137274 "Biphenyl hydrolase like" Q86WA6 6 3118374-3153578 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 102.8;liver: 79.0" "Cell type enhanced" "Detected in many" "Adipocytes: 88.4;Enterocytes: 94.5;Hepatocytes: 96.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Proximal tubules: 237629094.7" "Group enriched" "Detected in all" "cerebral cortex: 11730946.0;heart muscle: 11605992.6;kidney: 22572653.0;liver: 44327982.3" "HPA036752, HPA036753" Enhanced Approved Mitochondria NA NA 7000 "Cluster 18: Non-specific - Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 89: Adipocytes - Lipid metabolism" Mitochondria "HPA036752: , HPA036753: " "unprognostic (1.37e-1)" "unprognostic (2.25e-2)" "unprognostic (4.82e-2)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (3.63e-2)" "unprognostic (2.54e-1)" "unprognostic (9.89e-3)" "unprognostic (1.33e-3)" "unprognostic (3.59e-1)" "validated prognostic favorable (5.10e-9)" "validated prognostic favorable (5.14e-4)" "potential prognostic favorable (2.43e-5)" "unprognostic (1.03e-1)" "unprognostic (3.92e-3)" "unprognostic (2.71e-1)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (1.02e-1)" "unprognostic (6.47e-3)" "unprognostic (1.35e-1)" "unprognostic (2.41e-1)" "unprognostic (1.34e-1)" "unprognostic (4.04e-2)" "unprognostic (8.57e-2)" "unprognostic (8.20e-2)" "unprognostic (3.87e-1)" "unprognostic (2.62e-2)" "unprognostic (5.22e-3)" "unprognostic (1.14e-2)" "unprognostic (1.85e-1)" BRAF "BRAF-1, BRAF1" ENSG00000157764 "B-Raf proto-oncogene, serine/threonine kinase" P15056 7 140719327-140924929 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 2034.3" "Cell type enhanced" "Detected in all" "Neutrophils: 2034.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 4463095.3;Microglia and Neuropil: 3953113.2" "Group enriched" "Detected in many" "bone marrow: 663710.3;cerebral cortex: 1522106.4;Stomach: 994163.0" "HPA001328, CAB004552, HPA071048, CAB080447, CAB080451, CAB080452, CAB080531" Supported Supported "Vesicles,Plasma membrane,Primary cilium,Centriolar satellite,Basal body,Cytosol,Mid piece,Principal piece,End piece" No No "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 174 "Vesicles, Cytosol" "Plasma membrane, Primary cilium, Centriolar satellite, Basal body, Mid piece, Principal piece, End piece" "CAB004552: , CAB080447: , CAB080451: , CAB080452: , CAB080531: , HPA001328: , HPA071048: " "potential prognostic favorable (4.52e-4)" "unprognostic (8.04e-3)" "unprognostic (2.25e-1)" "unprognostic (1.00e-1)" "unprognostic (6.81e-2)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "unprognostic (1.79e-2)" "unprognostic (2.07e-2)" "unprognostic (4.01e-2)" "validated prognostic favorable (1.04e-4)" "validated prognostic favorable (2.24e-4)" "unprognostic (1.26e-1)" "unprognostic (3.93e-2)" "unprognostic (1.48e-1)" "unprognostic (7.31e-2)" "unprognostic (7.33e-3)" "unprognostic (1.95e-1)" "unprognostic (1.82e-1)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (2.08e-1)" "unprognostic (2.47e-2)" "unprognostic (1.21e-1)" "unprognostic (8.43e-2)" "unprognostic (2.20e-3)" "unprognostic (5.50e-2)" "unprognostic (2.47e-1)" "unprognostic (1.41e-1)" "unprognostic (1.77e-2)" "unprognostic (6.27e-2)" BRAP "BRAP2, IMP, RNF52" ENSG00000089234 "BRCA1 associated protein" Q7Z569 12 111642146-111685956 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.5" "Cell type enhanced" "Detected in many" "Early spermatids: 278.6;Late primary spermatocytes: 390.6;Late spermatids: 600.3" "Cell type enriched" "Detected in all" 5 "Spermatogenic cell types: 600.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 1083859.3" "Low tissue specificity" "Detected in many" "HPA040357, HPA058820" Approved Supported "Nuclear membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 23 Cytosol "Nuclear membrane" "HPA040357: , HPA058820: " "unprognostic (5.63e-2)" "unprognostic (7.17e-2)" "unprognostic (5.13e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-1)" "unprognostic (3.47e-2)" "unprognostic (2.03e-1)" "unprognostic (6.43e-2)" "unprognostic (8.91e-2)" "unprognostic (1.16e-2)" "validated prognostic favorable (9.17e-6)" "validated prognostic favorable (6.55e-4)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (2.10e-7)" "unprognostic (7.10e-3)" "unprognostic (4.23e-2)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (5.08e-2)" "unprognostic (7.82e-3)" "unprognostic (2.74e-1)" "unprognostic (5.03e-2)" "unprognostic (9.29e-2)" "unprognostic (1.63e-1)" "unprognostic (1.13e-2)" "unprognostic (3.16e-2)" "unprognostic (1.55e-1)" "unprognostic (2.45e-1)" "unprognostic (5.11e-2)" "unprognostic (7.31e-2)" BRCA2 "BRCC2, FACD, FAD, FAD1, FANCD, FANCD1, XRCC11" ENSG00000139618 "BRCA2 DNA repair associated" P51587 13 32315086-32400268 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Fanconi anemia, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.2;lymphoid tissue: 4.2;testis: 2.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 107.6;Early primary spermatocytes: 183.5;Erythrocyte progenitors: 150.6;Megakaryocyte progenitors: 120.3;Monocyte progenitors: 186.9;Neutrophil progenitors: 106.8;pDCs: 94.2;Plasma cells: 68.6;Respiratory deuterosomal cells: 58.1;Undifferentiated spermatogonia: 59.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 150.6;Megakaryocytes: 120.3;Mononuclear phagocytes: 186.9;Spermatogenic cell types: 183.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.2;choroid plexus epithelial cell: 9.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 2305 "Granulosa cells: 230531.3" "Not detected" "Not detected" HPA026815 Uncertain Supported Nucleoplasm,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 83 Nucleoplasm Cytosol "HPA026815: " "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (2.26e-1)" "unprognostic (1.17e-1)" "unprognostic (3.07e-2)" "unprognostic (8.91e-2)" "unprognostic (1.16e-2)" "unprognostic (9.86e-3)" "unprognostic (3.43e-1)" "potential prognostic unfavorable (3.60e-6)" "unprognostic (1.88e-2)" "unprognostic (2.73e-3)" "unprognostic (2.73e-2)" BRF1 "BRF, GTF3B, hBRF, TAF3B2, TAF3C, TFIIIB90" ENSG00000185024 "BRF1 RNA polymerase III transcription initiation factor subunit" Q92994 14 105209286-105315589 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 424712.3" "Group enriched" "Detected in some" "cerebral cortex: 58347.5;intestine: 80865.7;lymphoid tissue: 140775.3" "HPA051918, HPA074990" Approved Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 19 "Nucleoplasm, Nuclear bodies" "HPA051918: , HPA074990: " "unprognostic (2.20e-1)" "unprognostic (3.53e-1)" "unprognostic (7.31e-2)" "unprognostic (7.59e-2)" "unprognostic (2.34e-1)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (2.35e-2)" "unprognostic (1.27e-1)" "unprognostic (1.34e-3)" "potential prognostic favorable (1.76e-6)" "unprognostic (4.99e-3)" "unprognostic (9.12e-2)" "potential prognostic unfavorable (4.55e-5)" "unprognostic (5.66e-2)" "unprognostic (5.02e-3)" "unprognostic (1.40e-1)" "unprognostic (4.25e-2)" "unprognostic (4.96e-2)" "unprognostic (1.80e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (1.98e-5)" "unprognostic (5.22e-2)" "unprognostic (5.06e-2)" "unprognostic (2.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (7.33e-2)" "unprognostic (1.36e-1)" "unprognostic (2.18e-2)" "unprognostic (1.38e-1)" BRIX1 "BRIX, BXDC2, FLJ11100" ENSG00000113460 "Biogenesis of ribosomes BRX1" Q8TDN6 5 34915677-34925996 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 156.7;Migrating cytotrophoblasts: 169.0;Oocytes: 543.4;Syncytiotrophoblasts: 164.6" "Cell type enhanced" "Detected in all" "Oocytes: 543.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "intestine: 32602183.2" HPA039614 Enhanced "Nucleoli,Mitotic chromosome" Yes No 11000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 90 "Nucleoli, Mitotic chromosome" "HPA039614: " "unprognostic (3.13e-1)" "potential prognostic unfavorable (6.98e-4)" "unprognostic (1.89e-3)" "unprognostic (1.52e-1)" "unprognostic (1.71e-1)" "unprognostic (6.15e-2)" "unprognostic (4.30e-1)" "unprognostic (3.53e-1)" "unprognostic (4.57e-2)" "unprognostic (7.37e-3)" "unprognostic (3.74e-2)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (8.03e-6)" "validated prognostic unfavorable (4.30e-9)" "validated prognostic unfavorable (1.11e-4)" "unprognostic (2.45e-3)" "unprognostic (2.52e-3)" "unprognostic (3.38e-2)" "unprognostic (8.15e-2)" "unprognostic (5.32e-2)" "unprognostic (2.36e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (3.70e-3)" "unprognostic (3.37e-2)" "unprognostic (1.93e-1)" "unprognostic (1.85e-1)" "unprognostic (1.15e-2)" "unprognostic (7.51e-2)" "unprognostic (2.16e-1)" "unprognostic (2.43e-1)" "unprognostic (9.31e-3)" BRPF3 KIAA1286 ENSG00000096070 "Bromodomain and PHD finger containing 3" Q9ULD4 6 36196744-36232790 "Plasma proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Macrophages: 3852706.5;Neurons: 1657075.9" "Tissue enriched" "Detected in single" 194 "lymphoid tissue: 19355.7" HPA022787 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 Nucleoplasm Mitochondria "HPA022787: " "unprognostic (7.72e-2)" "unprognostic (5.65e-2)" "unprognostic (1.57e-1)" "unprognostic (1.29e-2)" "unprognostic (2.51e-1)" "unprognostic (4.16e-2)" "unprognostic (3.67e-1)" "unprognostic (4.50e-2)" "unprognostic (2.41e-2)" "unprognostic (2.82e-1)" "validated prognostic favorable (4.96e-7)" "validated prognostic favorable (6.19e-4)" "unprognostic (5.04e-2)" "unprognostic (1.63e-1)" "unprognostic (8.39e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-2)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "unprognostic (4.84e-2)" "unprognostic (1.20e-1)" "unprognostic (2.90e-1)" "unprognostic (2.08e-2)" "unprognostic (1.76e-1)" "unprognostic (4.08e-2)" "unprognostic (9.46e-3)" "unprognostic (1.79e-2)" "unprognostic (2.45e-1)" "unprognostic (4.06e-1)" "unprognostic (1.48e-2)" "unprognostic (4.88e-2)" BRWD1 "C21orf107, DCAF19, FLJ11315, N143, WDR9" ENSG00000185658 "Bromodomain and WD repeat domain containing 1" Q9NSI6 21 39184176-39321559 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 3308260.6;Oocytes: 851383.3" "Tissue enriched" "Detected in single" 213 "heart muscle: 21333.9" "HPA027343, HPA030943, HPA030944, HPA030945, CAB034184" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 73: Brain - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 8 "Nucleoplasm, Cytosol" "Nucleoli, Vesicles, Plasma membrane, Mitotic spindle" "CAB034184: , HPA027343: , HPA030943: , HPA030944: , HPA030945: " "unprognostic (1.69e-2)" "unprognostic (9.35e-2)" "unprognostic (5.01e-2)" "unprognostic (3.03e-2)" "unprognostic (6.37e-2)" "unprognostic (1.28e-1)" "unprognostic (2.20e-1)" "unprognostic (8.97e-3)" "unprognostic (1.20e-2)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (6.41e-2)" "unprognostic (1.11e-2)" "unprognostic (3.63e-3)" "unprognostic (6.07e-2)" "unprognostic (2.47e-1)" "unprognostic (5.58e-2)" "unprognostic (1.59e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (6.06e-2)" "unprognostic (8.13e-2)" "unprognostic (2.36e-2)" "unprognostic (2.02e-1)" "unprognostic (7.24e-3)" "unprognostic (2.01e-1)" "unprognostic (3.94e-2)" "unprognostic (5.09e-2)" "unprognostic (7.05e-2)" "unprognostic (2.61e-2)" "unprognostic (2.21e-1)" BTBD16 "C10orf87, Em:AC061711.1, FLJ25359" ENSG00000138152 "BTB domain containing 16" Q32M84 10 122271296-122338159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 7.9;testis: 7.3;urinary bladder: 18.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 54.9;Early spermatids: 118.9;Late primary spermatocytes: 87.8;Late spermatids: 86.3;Papillary tip epithelial cells: 29.4;Urothelial cells: 255.7" "Cell type enhanced" "Detected in many" "Alveolar cells: 54.9;Barrier epithelial cells: 255.7;Spermatogenic cell types: 118.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 16.7" "Cancer enriched" "Detected in some" 8 "Bladder Urothelial Carcinoma (TCGA): 15.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 4.2;pancreatic cancer: 5.1" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 2155 "Astrocytes and Neuropil: 215455.1" "Not detected" "Not detected" "HPA040529, HPA057638" Uncertain Uncertain Nucleoli,Cytosol Yes NA "Cluster 47: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" Nucleoli Cytosol "HPA040529: , HPA057638: " "unprognostic (2.07e-1)" "unprognostic (4.37e-1)" "unprognostic (1.39e-1)" "unprognostic (3.35e-3)" "unprognostic (4.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.58e-2)" "unprognostic (1.13e-1)" "unprognostic (6.64e-2)" BUB1 "BUB1A, BUB1L, hBUB1" ENSG00000169679 "BUB1 mitotic checkpoint serine/threonine kinase" O43683 2 110637528-110678063 "Enzymes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 11.2;lymphoid tissue: 25.6;testis: 28.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 43.6;Early primary spermatocytes: 119.8;Erythrocyte progenitors: 108.0;Granulosa cells: 39.7;Late primary spermatocytes: 75.2;Megakaryocyte progenitors: 67.6;Monocyte progenitors: 109.1;Neutrophil progenitors: 36.7;Oocytes: 50.7;Plasma cells: 44.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 108.0;Megakaryocytes: 67.6;Mononuclear phagocytes: 109.1;Spermatogenic cell types: 119.8" "Cell type enhanced" "Detected in some" "leukocyte: 3.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.7" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 39247 "Granulosa cells: 3924661.8" "Not detected" "Not detected" HPA006123 Supported Nucleoplasm,Cytosol NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 37 Nucleoplasm Cytosol "HPA006123: " "unprognostic (2.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.37e-1)" "unprognostic (2.83e-2)" "unprognostic (1.32e-2)" "unprognostic (1.66e-1)" "unprognostic (2.69e-1)" "unprognostic (3.96e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (8.26e-5)" "validated prognostic unfavorable (2.38e-5)" "validated prognostic unfavorable (3.02e-4)" "potential prognostic unfavorable (1.62e-6)" "validated prognostic unfavorable (2.73e-5)" "validated prognostic unfavorable (5.06e-7)" "potential prognostic unfavorable (4.27e-5)" "unprognostic (3.43e-3)" "unprognostic (1.18e-1)" "unprognostic (3.82e-2)" "unprognostic (6.74e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (5.63e-5)" "unprognostic (1.17e-2)" "unprognostic (6.59e-2)" "unprognostic (1.88e-2)" "unprognostic (1.63e-1)" "unprognostic (1.62e-2)" "unprognostic (1.56e-2)" "unprognostic (3.78e-1)" "unprognostic (6.01e-2)" "unprognostic (1.92e-1)" BUB1B "Bub1A, BUBR1, MAD3L, SSK1" ENSG00000156970 "BUB1 mitotic checkpoint serine/threonine kinase B" O60566 15 40161023-40221123 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.8;lymphoid tissue: 33.2;testis: 20.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 40.1;Differentiating spermatogonia: 23.8;Early primary spermatocytes: 64.0;Erythrocyte progenitors: 71.3;Megakaryocyte progenitors: 39.4;Monocyte progenitors: 80.1;Neutrophil progenitors: 43.7;Plasma cells: 18.4;Retinal ganglion cells: 23.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 40.1;Erythrocytes: 71.3;Megakaryocytes: 39.4;Mononuclear phagocytes: 80.1;Neutrophils: 43.7;Spermatogenic cell types: 64.0" "Cell type enriched" "Detected in many" 10 "choroid plexus epithelial cell: 43.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in single" 17 "choroid plexus: 17.0" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 9372 "Granulosa cells: 1148090.7;Oocytes: 726238.2" "Tissue enriched" "Detected in single" 1999 "bone marrow: 199875.3" HPA008419 Supported "Basal body,Cytosol" Yes Yes "Cluster 14: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 74 Cytosol "Basal body" "HPA008419: " "potential prognostic unfavorable (1.00e-3)" "unprognostic (6.05e-2)" "unprognostic (3.03e-1)" "unprognostic (4.67e-1)" "unprognostic (1.54e-1)" "unprognostic (4.05e-1)" "unprognostic (1.89e-1)" "unprognostic (7.91e-3)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (3.70e-4)" "validated prognostic unfavorable (4.04e-8)" "validated prognostic unfavorable (1.26e-5)" "potential prognostic unfavorable (4.10e-11)" "validated prognostic unfavorable (6.64e-6)" "validated prognostic unfavorable (4.00e-8)" "validated prognostic unfavorable (1.88e-5)" "validated prognostic unfavorable (2.38e-4)" "unprognostic (7.44e-2)" "unprognostic (2.31e-2)" "unprognostic (9.29e-2)" "unprognostic (4.81e-2)" "potential prognostic unfavorable (5.41e-4)" "unprognostic (1.46e-2)" "unprognostic (6.03e-2)" "unprognostic (1.63e-2)" "unprognostic (8.86e-2)" "unprognostic (4.12e-2)" "unprognostic (6.13e-2)" "unprognostic (1.73e-1)" "unprognostic (2.33e-1)" "unprognostic (1.72e-2)" BUD13 "Cwc26, fSAP71, MGC13125" ENSG00000137656 "BUD13 homolog" Q9BRD0 11 116748170-116772987 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 62.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 23360 "intestine: 1261423.6;lymphoid tissue: 3410504.2" "HPA038340, HPA038341" Enhanced Enhanced Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 13 Nucleoplasm "HPA038340: , HPA038341: " "unprognostic (2.91e-2)" "unprognostic (1.68e-2)" "unprognostic (7.53e-2)" "unprognostic (1.28e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-2)" "unprognostic (5.59e-2)" "unprognostic (2.11e-3)" "unprognostic (1.43e-1)" "unprognostic (8.59e-3)" "potential prognostic favorable (1.11e-5)" "unprognostic (3.82e-3)" "unprognostic (2.34e-2)" "unprognostic (1.07e-3)" "unprognostic (2.87e-1)" "unprognostic (2.30e-1)" "unprognostic (9.94e-3)" "unprognostic (7.00e-2)" "unprognostic (2.00e-1)" "unprognostic (1.71e-1)" "unprognostic (3.15e-2)" "unprognostic (7.47e-2)" "unprognostic (4.13e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (1.49e-1)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (2.03e-1)" BUD23 "MERM1, MGC19709, MGC2022, MGC5140, PP3381, WBMT, WBSCR22" ENSG00000071462 "BUD23 rRNA methyltransferase and ribosome maturation factor" O43709 7 73683597-73698212 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 619.6;Early primary spermatocytes: 723.4;Undifferentiated spermatogonia: 475.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 723.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13120 "T-cells: 1312023.5" "Tissue enriched" "Detected in some" "fallopian tube: 11937662.1" HPA052185 Approved Supported Nucleoplasm,Nucleoli Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 19 "Nucleoplasm, Nucleoli" "HPA052185: " "unprognostic (8.46e-2)" "unprognostic (2.25e-1)" "unprognostic (3.41e-2)" "unprognostic (1.89e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (4.11e-5)" "unprognostic (2.77e-2)" "unprognostic (1.06e-2)" "unprognostic (5.78e-3)" "unprognostic (3.87e-2)" "unprognostic (1.05e-3)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (2.43e-5)" "unprognostic (1.02e-2)" "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" "unprognostic (3.89e-1)" "unprognostic (1.79e-1)" "unprognostic (2.42e-2)" "unprognostic (1.68e-1)" "unprognostic (3.29e-1)" "unprognostic (6.51e-2)" "unprognostic (2.76e-2)" "unprognostic (9.99e-2)" "unprognostic (2.65e-1)" "unprognostic (3.59e-2)" "unprognostic (1.64e-1)" "unprognostic (5.59e-2)" "unprognostic (6.93e-2)" BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 26.0;skeletal muscle: 41.0;tongue: 27.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 46.0;Early spermatids: 30.7;Late primary spermatocytes: 57.0;Late spermatids: 93.9;Myonuclei: 119.5;Myosatellite cells: 22.1;Pituicytes/FSCs: 25.8;Smooth muscle cells: 23.9" "Group enriched" "Detected in many" 4 "Myocytes: 119.5;Spermatogenic cell types: 93.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.0;oligodendrocyte: 23.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 16.5" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Stomach - Chief cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Capillaries: 1438251.9;Cardiomyocytes: 4113782.8" "Tissue enriched" "Detected in some" "heart muscle: 7699249.8" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 30: White matter - Myelination" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 2 "Plasma membrane, Cell Junctions" "HPA014788: , HPA018176: " "unprognostic (1.30e-1)" "unprognostic (2.02e-1)" "unprognostic (2.35e-1)" "unprognostic (3.16e-1)" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (4.26e-1)" "unprognostic (7.36e-2)" "unprognostic (1.80e-2)" "unprognostic (2.41e-1)" "unprognostic (2.61e-2)" "unprognostic (7.33e-3)" "unprognostic (3.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.37e-1)" "unprognostic (7.02e-2)" "unprognostic (4.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.76e-2)" "unprognostic (3.04e-1)" "unprognostic (2.24e-2)" BYSL Enp1 ENSG00000112578 "Bystin like" Q13895 6 41921499-41933046 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 32.9;Epicardial cells: 36.4;Esophageal basal cells: 42.0;Oocytes: 59.9" "Cell type enhanced" "Detected in all" "Oocytes: 59.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" "lymphoid tissue: 1777745.0;ovary: 832195.5;Stomach: 635942.9" "HPA031217, HPA031219" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 288 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA031217: , HPA031219: " "unprognostic (1.15e-2)" "unprognostic (2.50e-2)" "unprognostic (2.45e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (1.51e-1)" "unprognostic (1.64e-2)" "unprognostic (4.14e-3)" "unprognostic (7.54e-3)" "unprognostic (7.11e-2)" "unprognostic (6.79e-2)" "unprognostic (3.52e-1)" "potential prognostic unfavorable (6.44e-4)" "validated prognostic unfavorable (6.91e-4)" "validated prognostic unfavorable (1.23e-6)" "unprognostic (3.31e-3)" "unprognostic (9.86e-3)" "unprognostic (2.90e-1)" "unprognostic (7.35e-3)" "unprognostic (9.05e-2)" "unprognostic (2.04e-2)" "unprognostic (5.31e-2)" "unprognostic (5.30e-1)" "unprognostic (1.04e-1)" "unprognostic (9.34e-3)" "unprognostic (1.40e-1)" "unprognostic (3.28e-1)" "unprognostic (8.12e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (4.95e-2)" C10orf82 "Em:AC016825.4, MGC33547" ENSG00000165863 "Chromosome 10 open reading frame 82" Q8WW14 10 116663696-116670264 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 69.0" "Group enriched" "Detected in some" 8 "Early spermatids: 1246.2;Late spermatids: 2527.3" "Cell type enriched" "Detected in many" 49 "Spermatogenic cell types: 2527.3" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 7.1" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 2.0;Testicular Germ Cell Tumor (TCGA): 2.0" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 103 "basophil: 10.2" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043022 Uncertain Mitochondria Yes NA "Cluster 46: Basophils - Proteolysis" "Cluster 23: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Mitochondria "HPA043022: " "unprognostic (1.61e-1)" "unprognostic (4.08e-2)" "unprognostic (1.54e-1)" "unprognostic (1.28e-1)" "unprognostic (7.18e-2)" C11orf24 DM4E3 ENSG00000171067 "Chromosome 11 open reading frame 24" Q96F05 11 68261338-68272001 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 182.6;Goblet cells: 63.1;Hepatocytes: 140.7;Plasma cells: 74.6" "Cell type enhanced" "Detected in all" "Enterocytes: 182.6;Hepatocytes: 140.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012411, HPA012748" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 7 "Nucleoplasm, Golgi apparatus" Vesicles "HPA012411: , HPA012748: " "unprognostic (1.01e-1)" "potential prognostic unfavorable (7.04e-4)" "unprognostic (2.53e-1)" "unprognostic (3.12e-3)" "unprognostic (1.00e-1)" "unprognostic (4.00e-1)" "unprognostic (3.42e-2)" "unprognostic (8.92e-3)" "unprognostic (8.66e-3)" "unprognostic (5.59e-2)" "unprognostic (3.06e-2)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.18e-2)" "unprognostic (9.01e-2)" "unprognostic (4.45e-2)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (1.77e-3)" "unprognostic (4.57e-2)" "unprognostic (7.25e-2)" "unprognostic (2.18e-2)" "unprognostic (8.97e-3)" "unprognostic (2.72e-2)" "unprognostic (2.44e-1)" "unprognostic (8.02e-2)" "unprognostic (3.45e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (1.17e-1)" "unprognostic (2.04e-2)" "unprognostic (3.92e-2)" C11orf68 "BLES03, P5326" ENSG00000175573 "Chromosome 11 open reading frame 68" Q9H3H3 11 65916810-65919062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Neurons: 26289279.6" "Low tissue specificity" "Detected in all" HPA045938 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 "Nucleoplasm, Nucleoli" "Nucleoli rim" "HPA045938: " "unprognostic (1.20e-2)" "unprognostic (4.02e-2)" "unprognostic (4.95e-2)" "unprognostic (3.11e-2)" "unprognostic (3.56e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-1)" "unprognostic (8.58e-2)" "potential prognostic favorable (1.95e-5)" "unprognostic (5.07e-2)" "unprognostic (1.13e-2)" "unprognostic (4.28e-3)" "unprognostic (1.98e-1)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (9.93e-4)" "unprognostic (8.85e-2)" "unprognostic (2.10e-1)" "unprognostic (4.56e-2)" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (1.42e-3)" "unprognostic (4.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (1.38e-1)" "unprognostic (5.44e-2)" "unprognostic (1.28e-2)" C11orf96 AG2 ENSG00000187479 "Chromosome 11 open reading frame 96" 11 43942637-43943878 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "blood vessel: 1697.4" "Group enriched" "Detected in some" 4 "Pericytes: 15.2;Smooth muscle cells: 18.4;Vascular smooth muscle cells: 37.1" "Group enriched" "Detected in some" 4 "Mural cells: 37.1;Smooth muscle cells: 18.4" "Cell type enriched" "Detected in single" 16 "vascular associated smooth muscle cell: 10.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 48.9" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Colon - Neutrophils" "Low region specificity" "Detected in all" HPA038843 Uncertain Approved "Nucleoplasm,Focal adhesion sites,Cytosol" No NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" "Nucleoplasm, Cytosol" "Focal adhesion sites" "HPA038843: " "unprognostic (2.12e-1)" "unprognostic (2.00e-1)" "unprognostic (3.42e-2)" "unprognostic (3.44e-2)" "unprognostic (4.74e-2)" "unprognostic (4.61e-2)" "unprognostic (1.26e-2)" "unprognostic (2.35e-3)" "unprognostic (1.33e-1)" "unprognostic (2.10e-1)" "unprognostic (2.71e-3)" "unprognostic (5.78e-3)" "unprognostic (1.20e-2)" "potential prognostic favorable (6.20e-4)" "unprognostic (9.74e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (2.86e-1)" "unprognostic (6.31e-2)" "unprognostic (1.83e-1)" "unprognostic (7.70e-2)" "unprognostic (2.66e-1)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (2.68e-3)" "unprognostic (1.58e-2)" "unprognostic (2.08e-2)" "unprognostic (1.07e-1)" "unprognostic (1.74e-3)" "unprognostic (4.32e-2)" C12orf40 FLJ40126 ENSG00000180116 "Chromosome 12 open reading frame 40" Q86WS4 12 39626167-39908300 "Predicted intracellular proteins" Meiosis "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 8.2" "Cell type enhanced" "Detected in many" "Adipocytes: 55.6;Cardiomyocytes: 205.2;Early primary spermatocytes: 73.1;Epicardial cells: 81.9;Fibro-adipogenic progenitors: 69.5;Late primary spermatocytes: 71.9;Other brain neurons: 53.6;Retinal ganglion cells: 77.3;Retinal horizontal cells: 118.2" "Cell type enhanced" "Detected in many" "Myocytes: 205.2;Neuronal cells: 118.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 13 "Testicular Germ Cell Tumor (TCGA): 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 146 "Fallopian tube cells: 14541.7;Neurons: 14722.8" "Tissue enriched" "Detected in single" 24250 "salivary gland: 2424981.9" HPA039032 Approved "Golgi apparatus,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 4 "Golgi apparatus" Cytosol "HPA039032: " "unprognostic (3.55e-1)" C12orf54 MGC35033 ENSG00000177627 "Chromosome 12 open reading frame 54" Q6X4T0 12 48482498-48496524 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 79 "testis: 49.9" "Cell type enriched" "Detected in some" 6 "Late spermatids: 4342.9" "Cell type enriched" "Detected in many" 141 "Spermatogenic cell types: 4342.9" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.0;Head and Neck Squamous Cell Carcinoma (TCGA): 1.2;Lung Squamous Cell Carcinoma (TCGA): 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 2.2;Gallbladder cancer: 3.4;head and neck cancer: 1.9" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 4079 "intestine: 407855.5" "HPA039919, HPA073090" Supported "Intermediate filaments,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Intermediate filaments" Cytosol "HPA039919: , HPA073090: " "unprognostic (2.91e-1)" "unprognostic (1.38e-1)" "unprognostic (5.71e-2)" "unprognostic (1.37e-1)" C14orf39 SIX6OS1 ENSG00000179008 "Chromosome 14 open reading frame 39" Q8N1H7 14 60396469-60515543 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, DNA recombination, Meiosis, Spermatogenesis" "Developmental protein" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "pituitary gland: 4.5;salivary gland: 4.4;testis: 10.1" "Cell type enhanced" "Detected in many" "Adipocytes: 69.4;Adrenal medulla cells: 63.8;Corticotrophs: 118.8;Early primary spermatocytes: 247.8;Gonadotrophs: 103.2;Lactotrophs: 216.5;Müller glia: 66.2;Myonuclei: 188.3;Pituitary stem cells: 171.9;Somatotrophs: 132.2;Thyrotrophs: 202.6" "Cell type enhanced" "Detected in many" "Myocytes: 188.3;Pituitary endocrine cells: 216.5;Spermatogenic cell types: 247.8;Stem cells: 171.9" "Cell type enhanced" "Detected in many" "mammillary body: 46.6" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.1" "Group enriched" "Detected in some" 10 "choroid plexus: 1.9;hypothalamus: 6.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.0" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Cell type enriched" "Detected in single" 4190 "Oocytes: 419036.0" "Group enriched" "Detected in some" 597 "intestine: 117398.1;lung: 31579.8;lymphoid tissue: 30031.8" HPA059518 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 47: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "Nucleoplasm, Nucleoli" "HPA059518: " "unprognostic (1.05e-3)" "unprognostic (1.18e-1)" "unprognostic (3.77e-1)" C17orf100 LOC388327 ENSG00000256806 "Chromosome 17 open reading frame 100" A8MU93 17 6651762-6693202 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 16.5;Epididymal principal cells: 22.5;Late primary spermatocytes: 13.7;Late spermatids: 23.9" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 22.5;Spermatogenic cell types: 23.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2168 "Astrocytes and Neuropil: 230405.1;Microglia and Neuropil: 203235.7" "Tissue enriched" "Detected in single" 3515 "cerebral cortex: 351545.3" HPA046824 Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 22: Epididymis - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA046824: " "unprognostic (1.45e-2)" "unprognostic (6.39e-2)" "unprognostic (7.90e-2)" "unprognostic (3.23e-1)" "unprognostic (8.29e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.04e-2)" "unprognostic (3.93e-1)" "potential prognostic favorable (3.04e-5)" "unprognostic (2.20e-2)" "unprognostic (1.50e-2)" "unprognostic (4.71e-2)" "unprognostic (5.19e-2)" "unprognostic (2.62e-1)" "unprognostic (1.94e-1)" "unprognostic (2.35e-1)" "unprognostic (2.86e-3)" "unprognostic (5.25e-3)" "unprognostic (6.54e-2)" "unprognostic (2.44e-2)" "unprognostic (1.47e-1)" "unprognostic (4.82e-2)" "unprognostic (6.63e-2)" "unprognostic (9.83e-2)" "unprognostic (3.67e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (2.60e-1)" "unprognostic (2.22e-1)" C17orf50 ENSG00000270806 "Chromosome 17 open reading frame 50" Q8WW18 17 35760887-35765079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 84 "testis: 94.2" "Group enriched" "Detected in some" 80 "Early spermatids: 695.3;Late primary spermatocytes: 596.1;Late spermatids: 2113.5" "Cell type enriched" "Detected in some" 150 "Spermatogenic cell types: 2113.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 2.1" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043184, HPA063464" Supported Nucleoplasm Yes NA "Cluster 30: Non-specific - DNA binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 6 Nucleoplasm "HPA043184: , HPA063464: " C18orf25 "Ark2N, ARKL1, MGC12909, RNF111L1" ENSG00000152242 "Chromosome 18 open reading frame 25" Q96B23 18 46173553-46266992 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 250.0;Esophageal apical cells: 777.4;Neutrophil progenitors: 295.7;Neutrophils: 234.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 777.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "heart muscle: 23237150.0;lymphoid tissue: 6210714.2" "HPA051314, HPA051899" Approved Approved Nucleoplasm,Cytosol No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 22 Nucleoplasm Cytosol "HPA051314: , HPA051899: " "unprognostic (1.55e-3)" "unprognostic (4.66e-2)" "unprognostic (3.51e-1)" "unprognostic (5.41e-3)" "unprognostic (4.45e-2)" "unprognostic (1.42e-1)" "unprognostic (3.05e-1)" "unprognostic (8.87e-2)" "unprognostic (6.83e-2)" "unprognostic (3.57e-2)" "unprognostic (1.18e-3)" "unprognostic (1.35e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (9.48e-4)" "unprognostic (1.55e-2)" "unprognostic (1.92e-1)" "unprognostic (9.69e-2)" "unprognostic (8.83e-2)" "unprognostic (1.70e-3)" "unprognostic (2.52e-1)" "unprognostic (3.45e-1)" "unprognostic (3.54e-2)" "unprognostic (2.98e-3)" "unprognostic (2.69e-2)" "unprognostic (1.01e-2)" "unprognostic (6.16e-2)" "unprognostic (9.02e-2)" "unprognostic (2.56e-2)" "unprognostic (1.35e-1)" "unprognostic (1.28e-1)" "unprognostic (1.80e-1)" C19orf12 "DKFZP762D096, MGC10922, MPAN, NBIA4, SPG43" ENSG00000131943 "Chromosome 19 open reading frame 12" Q9NSK7 19 29698937-29715789 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 110.6;tongue: 98.1" "Cell type enhanced" "Detected in many" "Adipocytes: 133.0;Enterocytes: 160.2" "Cell type enhanced" "Detected in many" "Enterocytes: 160.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" HPA046930 Approved Supported Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 76: Non-specific - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" Cytosol "HPA046930: " "unprognostic (7.11e-2)" "unprognostic (1.47e-1)" "unprognostic (5.13e-2)" "unprognostic (2.87e-3)" "unprognostic (1.80e-1)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.41e-1)" "unprognostic (6.08e-2)" "unprognostic (7.50e-3)" "unprognostic (1.87e-3)" "unprognostic (9.14e-2)" "unprognostic (3.39e-1)" "unprognostic (2.91e-2)" "potential prognostic favorable (3.34e-5)" "unprognostic (1.36e-1)" "unprognostic (3.00e-1)" "unprognostic (3.86e-2)" "unprognostic (3.23e-1)" "unprognostic (4.33e-3)" "unprognostic (2.30e-2)" "unprognostic (1.17e-1)" "unprognostic (1.40e-2)" "unprognostic (1.03e-1)" "unprognostic (4.88e-2)" "unprognostic (4.06e-2)" "unprognostic (2.81e-1)" "unprognostic (9.03e-2)" "unprognostic (6.21e-2)" "unprognostic (1.70e-2)" "unprognostic (5.57e-2)" C19orf25 FLJ36666 ENSG00000119559 "Chromosome 19 open reading frame 25" Q9UFG5 19 1461143-1479219 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "heart muscle: 8716618.2" "HPA050270, HPA067491" Approved Approved "Intermediate filaments" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 65: Non-specific - Cell growth & division" 45 "Intermediate filaments" "HPA050270: , HPA067491: " "unprognostic (2.16e-2)" "unprognostic (1.04e-1)" "unprognostic (7.13e-2)" "unprognostic (1.74e-1)" "unprognostic (1.03e-1)" "unprognostic (3.82e-2)" "unprognostic (1.90e-1)" "unprognostic (6.94e-2)" "unprognostic (3.77e-3)" "unprognostic (1.54e-3)" "potential prognostic favorable (2.47e-6)" "unprognostic (2.15e-3)" "potential prognostic favorable (2.88e-4)" "unprognostic (1.60e-3)" "unprognostic (2.05e-1)" "unprognostic (3.45e-1)" "unprognostic (3.42e-2)" "unprognostic (1.52e-2)" "unprognostic (2.79e-1)" "unprognostic (4.61e-3)" "unprognostic (2.56e-1)" "unprognostic (2.47e-3)" "unprognostic (5.05e-2)" "unprognostic (2.85e-1)" "unprognostic (8.38e-2)" "unprognostic (7.36e-2)" "unprognostic (6.35e-2)" "unprognostic (1.02e-2)" "unprognostic (1.29e-1)" "unprognostic (4.39e-1)" "unprognostic (1.49e-2)" C19orf33 "H2RSP, IMUP, IMUP-1, IMUP-2" ENSG00000167644 "Chromosome 19 open reading frame 33" Q9GZP8 19 38304164-38305006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 689.2;skin 1: 440.6" "Cell type enhanced" "Detected in many" "Colonocytes: 2467.9;Enteric transient amplifying cells: 531.9;Enterocytes: 1591.9;Esophageal apical cells: 2363.4;Esophageal suprabasal cells: 878.3;Fallopian secretory cells: 537.1;Foveolar cells: 752.4;Goblet cells: 851.2" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 2363.4;Enterocytes: 2467.9" "Group enriched" "Detected in some" 15 "endothelial cell: 5.5;fibroblast: 5.1;vascular associated smooth muscle cell: 2.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 10 "myeloid DC: 22.3" "Lineage enriched" "Detected in many" 10 "dendritic cells: 22.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 3253 "fallopian tube: 325315.9" "HPA054406, HPA059696" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 170000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Nucleoplasm "Plasma membrane, Cytosol" "HPA054406: , HPA059696: " "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (3.76e-3)" "unprognostic (9.97e-2)" "unprognostic (6.00e-2)" "unprognostic (5.79e-3)" "unprognostic (5.84e-3)" "unprognostic (1.58e-2)" "unprognostic (1.13e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (2.22e-5)" "unprognostic (1.84e-1)" "unprognostic (2.06e-2)" "potential prognostic unfavorable (1.19e-6)" "unprognostic (1.21e-1)" "unprognostic (2.69e-2)" "unprognostic (1.26e-3)" "unprognostic (9.77e-3)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (2.55e-1)" "unprognostic (4.49e-2)" "unprognostic (1.93e-1)" "unprognostic (5.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" "unprognostic (3.27e-2)" "unprognostic (3.24e-2)" C19orf38 HIDE1 ENSG00000214212 "Chromosome 19 open reading frame 38" A8MVS5 19 10836575-10869790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 92.6" "Cell type enhanced" "Detected in many" "cDC: 36.0;Early primary spermatocytes: 38.0;Monocyte progenitors: 45.1;monocytes: 104.3;Neutrophil progenitors: 75.7;Neutrophils: 122.3" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 104.3;Neutrophils: 122.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 16.3;leukocyte: 7.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "classical monocyte: 282.7;eosinophil: 169.8;intermediate monocyte: 312.8;myeloid DC: 162.4;neutrophil: 231.0;non-classical monocyte: 394.4" "Group enriched" "Detected in all" 20 "dendritic cells: 162.4;granulocytes: 231.0;monocytes: 394.4" "Group enriched" "Detected in some" 5 "Leukemia: 12.4;lymphoma: 6.1;Myeloma: 5.7" "Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 9752 "Neutrophils: 975179.0" "Tissue enriched" "Detected in some" "lymphoid tissue: 892578.3" "HPA012150, HPA055027" Uncertain "Golgi apparatus,Plasma membrane,Cytosol" No NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Cytosol "Golgi apparatus, Plasma membrane" "HPA012150: , HPA055027: " "unprognostic (1.82e-1)" "unprognostic (4.32e-2)" "unprognostic (4.24e-2)" "potential prognostic favorable (6.29e-7)" "unprognostic (6.33e-2)" "unprognostic (2.43e-1)" "unprognostic (3.60e-1)" "unprognostic (8.12e-2)" "unprognostic (1.84e-2)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (4.71e-2)" "unprognostic (7.28e-2)" "unprognostic (2.57e-1)" "unprognostic (8.90e-2)" "unprognostic (4.07e-2)" "unprognostic (1.74e-1)" "unprognostic (4.57e-2)" "unprognostic (3.77e-1)" "unprognostic (3.08e-1)" "unprognostic (1.97e-1)" "unprognostic (2.72e-1)" "unprognostic (8.93e-2)" "unprognostic (3.11e-1)" "unprognostic (5.47e-3)" "unprognostic (4.27e-1)" "unprognostic (3.58e-3)" "unprognostic (2.38e-1)" "unprognostic (5.92e-2)" "unprognostic (1.14e-2)" "unprognostic (4.31e-2)" C19orf44 FLJ21742 ENSG00000105072 "Chromosome 19 open reading frame 44" Q9H6X5 19 16496394-16521352 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 59.6;Epicardial cells: 31.8;Late spermatids: 127.1" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 127.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1960 "Fallopian tube cells: 196040.7" "Not detected" "Not detected" "HPA041683, HPA049414" Uncertain Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Primary cilium,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Nucleoplasm "Nuclear bodies, Golgi apparatus, Primary cilium, Cytosol" "HPA041683: , HPA049414: " "unprognostic (2.76e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (6.11e-5)" "unprognostic (1.80e-1)" "unprognostic (3.53e-2)" "unprognostic (2.13e-1)" "unprognostic (2.49e-1)" "unprognostic (2.32e-1)" "unprognostic (9.14e-2)" "unprognostic (6.39e-2)" "unprognostic (7.40e-3)" "unprognostic (1.79e-3)" "unprognostic (2.85e-1)" "unprognostic (3.37e-2)" "unprognostic (1.84e-1)" "unprognostic (4.50e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (7.96e-3)" "unprognostic (2.50e-1)" "unprognostic (2.18e-1)" "unprognostic (2.67e-2)" "unprognostic (2.69e-2)" "unprognostic (2.49e-3)" "unprognostic (5.75e-2)" "unprognostic (1.52e-1)" "unprognostic (2.05e-2)" "unprognostic (1.04e-1)" "unprognostic (1.27e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-2)" C19orf53 "HSPC023, LYDG10" ENSG00000104979 "Chromosome 19 open reading frame 53" Q9UNZ5 19 13774456-13778773 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 681.5;Esophageal suprabasal cells: 652.1;Late spermatids: 1069.6" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1069.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 2333402.2;T-cells: 4670811.1" "Group enriched" "Detected in many" "kidney: 1274522.1;liver: 1008623.8;lymphoid tissue: 1241492.4" "HPA059928, HPA061291" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" "Nucleoplasm, Nucleoli" "HPA059928: , HPA061291: " "unprognostic (2.88e-2)" "unprognostic (5.43e-2)" "unprognostic (3.41e-1)" "unprognostic (3.24e-3)" "unprognostic (2.15e-1)" "unprognostic (4.53e-2)" "unprognostic (8.57e-2)" "unprognostic (8.05e-2)" "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (3.30e-5)" "unprognostic (2.33e-3)" "unprognostic (3.51e-1)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (5.96e-3)" "unprognostic (6.87e-3)" "unprognostic (2.50e-3)" "unprognostic (2.21e-3)" "unprognostic (6.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.03e-1)" "unprognostic (2.44e-1)" "unprognostic (2.80e-1)" "unprognostic (4.25e-2)" "unprognostic (3.99e-2)" "unprognostic (2.50e-1)" "unprognostic (2.59e-1)" "unprognostic (3.59e-1)" "unprognostic (9.66e-2)" "unprognostic (3.54e-2)" "unprognostic (1.86e-1)" C19orf54 FLJ41131 ENSG00000188493 "Chromosome 19 open reading frame 54" Q5BKX5 19 40740856-40751553 "Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 32.6;Cardiomyocytes: 80.4;Epicardial cells: 113.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 113.7;Myocytes: 80.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 3936304.7" "Tissue enhanced" "Detected in some" "bone marrow: 20098.9" "HPA059043, HPA059628" Approved Approved "Intermediate filaments,Centriolar satellite" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Intermediate filaments" "Centriolar satellite" "HPA059043: , HPA059628: " "unprognostic (1.42e-1)" "unprognostic (1.33e-1)" "unprognostic (3.24e-1)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (5.75e-2)" "unprognostic (3.03e-2)" "unprognostic (1.08e-1)" "unprognostic (1.07e-1)" "unprognostic (4.34e-2)" "unprognostic (1.57e-3)" "potential prognostic unfavorable (1.55e-5)" "unprognostic (1.27e-2)" "unprognostic (9.10e-3)" "unprognostic (1.80e-1)" "unprognostic (4.14e-3)" "unprognostic (3.77e-1)" "unprognostic (5.98e-2)" "unprognostic (4.83e-3)" "unprognostic (2.12e-1)" "unprognostic (8.28e-2)" "unprognostic (1.28e-1)" "unprognostic (4.43e-2)" "unprognostic (7.42e-2)" "unprognostic (2.28e-3)" "unprognostic (2.27e-1)" "unprognostic (1.02e-2)" "unprognostic (2.17e-1)" "unprognostic (2.88e-1)" "unprognostic (1.02e-3)" "unprognostic (2.41e-1)" C19orf73 FLJ10490 ENSG00000221916 "Chromosome 19 open reading frame 73" Q9NVV2 19 49118402-49119143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.1" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 22.7;Esophageal suprabasal cells: 8.7;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 22.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA062719 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 3 "Nucleoplasm, Cytosol" "HPA062719: " "unprognostic (5.11e-2)" "unprognostic (1.62e-1)" "unprognostic (1.28e-1)" "unprognostic (2.87e-3)" "unprognostic (3.22e-2)" "unprognostic (1.25e-1)" "unprognostic (2.44e-2)" "unprognostic (1.35e-1)" "unprognostic (2.37e-2)" "unprognostic (2.09e-1)" "unprognostic (6.32e-2)" "unprognostic (1.49e-2)" "unprognostic (1.50e-1)" "unprognostic (3.18e-1)" "unprognostic (3.28e-1)" "unprognostic (1.79e-2)" "unprognostic (2.25e-1)" "potential prognostic favorable (9.88e-4)" "unprognostic (1.60e-1)" "unprognostic (4.33e-2)" "unprognostic (1.30e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-1)" "unprognostic (1.74e-1)" "unprognostic (2.79e-1)" "unprognostic (1.86e-1)" C1orf109 FLJ20508 ENSG00000116922 "Chromosome 1 open reading frame 109" Q9NX04 1 37681570-37692249 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 41.1;Suprabasal keratinocytes: 44.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1228 "Granulosa cells: 122756.1" "Group enriched" "Detected in some" "intestine: 285534.1;kidney: 276208.5;liver: 766729.6" "HPA027110, HPA027127" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 26: Keratinocytes - Keratinization" 126 Cytosol "Nucleoplasm, Nucleoli" "HPA027110: , HPA027127: " "unprognostic (2.89e-1)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (3.21e-4)" "unprognostic (8.33e-3)" "unprognostic (9.22e-2)" "unprognostic (2.15e-1)" "unprognostic (1.09e-1)" "unprognostic (5.29e-2)" "unprognostic (6.45e-2)" "unprognostic (2.21e-1)" "potential prognostic favorable (4.00e-6)" "unprognostic (1.47e-2)" "unprognostic (1.94e-1)" "validated prognostic unfavorable (1.71e-4)" "validated prognostic unfavorable (7.76e-5)" "unprognostic (2.03e-1)" "unprognostic (3.31e-2)" "unprognostic (2.61e-1)" "unprognostic (5.21e-3)" "unprognostic (1.21e-1)" "unprognostic (1.09e-2)" "unprognostic (1.49e-1)" "unprognostic (8.42e-2)" "unprognostic (8.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.51e-1)" "unprognostic (2.10e-2)" "unprognostic (1.75e-1)" "unprognostic (2.15e-1)" "unprognostic (2.49e-2)" "unprognostic (6.30e-2)" C1orf116 "FLJ36507, MGC2742, MGC4309, SARG" ENSG00000182795 "Chromosome 1 open reading frame 116" Q9BW04 1 207018522-207032756 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.1;lung: 68.8;stomach 1: 55.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 244.4;Esophageal apical cells: 748.6;Esophageal suprabasal cells: 127.9;Foveolar cells: 126.2;Ocular epithelial cells: 379.8;Transitional alveolar cells: 137.1;Urothelial cells: 220.3" "Cell type enhanced" "Detected in many" "Alveolar cells: 244.4;Apical squamous epithelial cells: 748.6;Barrier epithelial cells: 379.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 118.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 57.3" "Colon - Colon enterocytes, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" "Alveolar cell types: 24137037.6;Keratinocytes: 15615670.1" "Group enriched" "Detected in many" "lung: 7913211.1;Stomach: 10363770.8" "HPA011888, HPA011889" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 62000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 4 "Plasma membrane, Cytosol" "HPA011888: , HPA011889: " "unprognostic (1.58e-2)" "unprognostic (2.54e-2)" "unprognostic (4.46e-2)" "unprognostic (1.19e-2)" "unprognostic (2.66e-1)" "potential prognostic unfavorable (1.93e-4)" "unprognostic (1.12e-1)" "unprognostic (2.60e-2)" "unprognostic (2.41e-3)" "unprognostic (2.02e-1)" "unprognostic (3.03e-1)" "unprognostic (6.38e-2)" "unprognostic (8.80e-3)" "unprognostic (7.19e-2)" "unprognostic (4.28e-2)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.02e-1)" "unprognostic (1.36e-1)" "unprognostic (7.84e-2)" "unprognostic (1.14e-1)" "unprognostic (1.72e-2)" "unprognostic (2.10e-1)" "unprognostic (2.49e-1)" "unprognostic (6.52e-2)" "unprognostic (1.19e-1)" C1orf159 FLJ20584 ENSG00000131591 "Chromosome 1 open reading frame 159" Q96HA4 1 1081818-1116361 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 22.4" "Cell type enhanced" "Detected in many" "Late spermatids: 228.0" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 228.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010019, HPA075399" Approved Approved "Nucleoli rim,Mitotic chromosome,Intermediate filaments" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nucleoli rim, Mitotic chromosome" "Intermediate filaments" "HPA010019: , HPA075399: " "unprognostic (4.71e-2)" "unprognostic (4.50e-3)" "unprognostic (2.19e-1)" "unprognostic (7.83e-2)" "unprognostic (8.06e-2)" "unprognostic (5.25e-3)" "unprognostic (7.58e-2)" "unprognostic (2.98e-2)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (5.74e-4)" "potential prognostic unfavorable (8.18e-5)" "unprognostic (1.01e-2)" "unprognostic (4.93e-1)" "potential prognostic unfavorable (1.59e-7)" "unprognostic (2.19e-2)" "unprognostic (2.78e-3)" "unprognostic (1.11e-1)" "unprognostic (5.97e-2)" "unprognostic (2.97e-1)" "unprognostic (6.72e-2)" "unprognostic (7.25e-3)" "unprognostic (6.42e-2)" "unprognostic (9.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.59e-1)" "unprognostic (3.74e-2)" "unprognostic (1.16e-1)" "unprognostic (2.97e-2)" "unprognostic (2.66e-2)" "unprognostic (5.85e-2)" "unprognostic (1.99e-1)" C1orf226 FLJ13137 ENSG00000239887 "Chromosome 1 open reading frame 226" A1L170 1 162378841-162386812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Bergmann glia: 26.7;Early spermatids: 29.1;Hepatocytes: 32.1;Late spermatids: 62.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 31.9;Hepatocytes: 32.1;Spermatogenic cell types: 62.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 24.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Glomeruli: 2165835.8;Large ducts: 945960.0" "Tissue enriched" "Detected in single" 189 "liver: 18944.4" "HPA052251, HPA074060" Approved Approved Nucleoplasm NA NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 Nucleoplasm "HPA052251: , HPA074060: " "unprognostic (1.37e-1)" "potential prognostic favorable (4.90e-4)" "unprognostic (3.82e-1)" "unprognostic (5.90e-2)" "unprognostic (7.60e-2)" "unprognostic (8.01e-3)" "unprognostic (1.13e-2)" "unprognostic (1.90e-1)" "unprognostic (6.24e-2)" "unprognostic (1.59e-2)" "potential prognostic favorable (2.00e-5)" "unprognostic (3.66e-3)" "unprognostic (1.34e-1)" "unprognostic (3.26e-1)" "unprognostic (1.05e-1)" "unprognostic (5.64e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (3.49e-4)" "unprognostic (1.42e-1)" "unprognostic (2.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.07e-2)" "unprognostic (8.06e-2)" "unprognostic (6.57e-3)" "unprognostic (3.85e-2)" "unprognostic (2.85e-2)" "unprognostic (2.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.02e-1)" "unprognostic (2.36e-1)" C1orf35 "MGC4174, MMTAG2" ENSG00000143793 "Chromosome 1 open reading frame 35" Q9BU76 1 228100726-228105411 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 2529775.9" "Group enriched" "Detected in many" "blood vessel: 1668701.3;intestine: 5257059.5;lymphoid tissue: 1683581.3;skin: 2847099.4" HPA046175 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 37: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 52 "Nuclear speckles, Plasma membrane" Cytosol "HPA046175: " "unprognostic (2.96e-2)" "unprognostic (6.95e-2)" "unprognostic (2.37e-1)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.90e-2)" "unprognostic (5.87e-2)" "unprognostic (2.94e-3)" "unprognostic (1.35e-1)" "unprognostic (3.91e-1)" "unprognostic (4.86e-2)" "unprognostic (6.80e-2)" "unprognostic (8.97e-3)" "unprognostic (3.40e-3)" "unprognostic (2.70e-2)" "unprognostic (1.31e-1)" "unprognostic (4.67e-2)" "unprognostic (9.47e-2)" "unprognostic (2.25e-2)" "potential prognostic favorable (4.95e-4)" "unprognostic (4.75e-2)" "unprognostic (9.66e-2)" "potential prognostic unfavorable (5.43e-4)" "unprognostic (3.82e-2)" "unprognostic (8.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.81e-2)" "unprognostic (9.53e-2)" "unprognostic (2.36e-2)" "unprognostic (1.65e-1)" "unprognostic (2.00e-1)" C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.4" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 4.4;Endometrial luminal cells: 9.8;Epididymal basal cells: 6.8;Epididymal clear cells: 4.1;Esophageal basal cells: 3.7;Esophageal suprabasal cells: 5.2;Oocytes: 4.6;Suprabasal keratinocytes: 3.7;Urothelial cells: 4.3" "Cell type enhanced" "Detected in many" "Basal cells: 6.8;Luminal cells: 9.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 58: Skin - Keratinization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 5 "Plasma membrane, Cytosol" "HPA028496: " "unprognostic (1.03e-1)" "unprognostic (1.59e-1)" "unprognostic (8.16e-2)" "potential prognostic unfavorable (9.77e-6)" "unprognostic (4.08e-2)" "unprognostic (1.38e-1)" "unprognostic (2.94e-1)" "unprognostic (1.31e-2)" "unprognostic (3.47e-1)" "potential prognostic favorable (6.17e-5)" "unprognostic (1.12e-3)" "unprognostic (5.44e-2)" "unprognostic (4.65e-2)" "unprognostic (3.52e-1)" "unprognostic (2.16e-1)" "unprognostic (1.31e-2)" "unprognostic (2.81e-1)" "unprognostic (1.43e-1)" "unprognostic (7.00e-2)" "unprognostic (3.57e-2)" "unprognostic (2.13e-1)" "unprognostic (2.86e-1)" "unprognostic (2.60e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (9.69e-2)" "unprognostic (1.57e-1)" "unprognostic (1.48e-1)" "unprognostic (2.79e-2)" "unprognostic (1.71e-1)" C1QTNF6 "CTRP6, ZACRP6" ENSG00000133466 "C1q and TNF related 6" Q9BXI9 22 37180166-37199385 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 29.8;placenta: 27.9" "Cell type enriched" "Detected in many" 10 "Extravillous trophoblasts: 598.7" "Cell type enriched" "Detected in many" 19 "Trophoblast cells: 598.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 599 "Granulosa cells: 59928.9" "Not detected" "Not detected" HPA002042 Enhanced Approved Nucleoplasm "Secreted to blood" "Complement pathway" No No 354000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 75: Ovary - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 3 Nucleoplasm "HPA002042: " "unprognostic (1.22e-1)" "unprognostic (8.88e-2)" "unprognostic (6.85e-2)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (7.42e-2)" "unprognostic (9.07e-2)" "unprognostic (7.82e-3)" "unprognostic (2.93e-2)" "unprognostic (3.01e-2)" "unprognostic (8.33e-2)" "potential prognostic unfavorable (4.16e-8)" "unprognostic (1.45e-2)" "unprognostic (5.95e-2)" "unprognostic (1.37e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (2.55e-9)" "unprognostic (2.23e-3)" "unprognostic (1.43e-1)" "unprognostic (3.89e-2)" "unprognostic (6.92e-2)" "unprognostic (6.21e-2)" "unprognostic (7.33e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (7.85e-2)" "unprognostic (1.43e-1)" "unprognostic (6.87e-2)" "unprognostic (6.67e-3)" "unprognostic (8.24e-3)" "unprognostic (9.72e-2)" "unprognostic (6.66e-3)" "unprognostic (5.88e-3)" C20orf173 dJ477O4.4 ENSG00000125975 "Chromosome 20 open reading frame 173" Q96LM9 20 35523186-35529652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 170 "testis: 33.6" "Group enriched" "Detected in some" 8 "Early spermatids: 503.9;Late spermatids: 148.5" "Cell type enriched" "Detected in single" 554 "Spermatogenic cell types: 503.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 16899 "Alveolar cell types: 1689854.3" "Tissue enriched" "Detected in single" 3744 "lung: 374390.3" HPA076859 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Nucleoplasm "Vesicles, Plasma membrane" "HPA076859: " C21orf58 ENSG00000160298 "Chromosome 21 open reading frame 58" P58505 21 46300181-46323875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 24.9;pituitary gland: 20.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 104.3;Endometrial ciliated cells: 157.9;Ependymal cells: 74.7;Epididymal efferent duct ciliated cells: 139.8;Erythrocyte progenitors: 115.2;Fallopian tube ciliated cells: 192.4;Platelets: 91.9;Respiratory ciliated cells: 231.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 231.0;Erythrocytes: 115.2;Spermatogenic cell types: 104.3" "Cell type enriched" "Detected in all" 4 "ependymal cell: 75.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 4.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 4.4" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5825 "Fallopian tube cells: 582522.8" "Tissue enriched" "Detected in single" 205 "fallopian tube: 20456.8" "HPA035110, HPA035111" Uncertain Approved "Nucleoplasm,Nuclear bodies,Primary cilium transition zone" NA Yes "Cluster 46: Basophils - Proteolysis" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 46: Brainstem - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 107: Ciliated cells - Cilia assembly & function" Nucleoplasm "Nuclear bodies, Primary cilium transition zone" "HPA035110: , HPA035111: " "unprognostic (1.34e-1)" "unprognostic (2.04e-1)" "unprognostic (6.34e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-2)" "unprognostic (4.48e-1)" "unprognostic (2.79e-2)" "unprognostic (3.45e-1)" "unprognostic (1.10e-3)" "unprognostic (1.02e-2)" "validated prognostic unfavorable (1.15e-6)" "validated prognostic unfavorable (4.32e-4)" "unprognostic (2.94e-1)" "unprognostic (5.54e-3)" "unprognostic (2.22e-3)" "unprognostic (1.34e-1)" "unprognostic (3.48e-2)" "unprognostic (1.63e-1)" "unprognostic (1.53e-2)" "unprognostic (2.24e-1)" "unprognostic (2.19e-2)" "unprognostic (2.21e-3)" "unprognostic (2.85e-1)" "unprognostic (1.36e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" "unprognostic (7.43e-2)" "unprognostic (1.94e-1)" "unprognostic (5.72e-2)" "unprognostic (1.82e-1)" "unprognostic (9.22e-2)" C2CD3 DKFZP586P0123 ENSG00000168014 "C2 domain containing 3 centriole elongation regulator" Q4AC94 11 74012718-74171210 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 122.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 21.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 3106569.4;Granulosa cells: 833880.3" "Tissue enriched" "Detected in some" "fallopian tube: 198164.5" "HPA038552, HPA038553, HPA040433" Approved Supported "Nucleoplasm,Centrosome,Basal body,Acrosome,Equatorial segment,Principal piece" NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 "Nucleoplasm, Centrosome, Basal body" "Acrosome, Equatorial segment, Principal piece" "HPA038552: , HPA038553: , HPA040433: " "unprognostic (9.70e-2)" "unprognostic (2.13e-1)" "unprognostic (1.14e-2)" "unprognostic (9.10e-2)" "unprognostic (6.85e-3)" "unprognostic (1.53e-1)" "unprognostic (1.57e-1)" "unprognostic (6.85e-2)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (3.75e-4)" "potential prognostic unfavorable (5.87e-6)" "unprognostic (2.28e-1)" "unprognostic (2.05e-1)" "unprognostic (3.81e-2)" "unprognostic (2.78e-2)" "unprognostic (2.43e-1)" "unprognostic (6.29e-2)" "unprognostic (3.04e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.34e-1)" "unprognostic (9.36e-3)" "unprognostic (5.44e-3)" "unprognostic (1.25e-2)" "unprognostic (1.24e-2)" "unprognostic (2.73e-3)" "unprognostic (1.99e-1)" "unprognostic (3.88e-2)" "unprognostic (2.65e-1)" "unprognostic (8.97e-2)" "unprognostic (1.31e-1)" C2CD4C "FAM148C, KIAA1957, NLF3" ENSG00000183186 "C2 calcium dependent domain containing 4C" Q8TF44 19 405445-409147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 27.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.2;Brain inhibitory neurons: 3.7;Fallopian secretory cells: 2.6;Lymphatic endothelial cells: 5.7;Medullary thymic epithelial cells: 2.4;Neuroendocrine cells: 4.3;Oligodendrocyte progenitor cells: 8.6;Other brain neurons: 17.7;Pituicytes/FSCs: 2.7;Rod photoreceptor cells: 4.0;Undifferentiated spermatogonia: 2.8;Vascular endothelial cells: 3.7" "Cell type enhanced" "Detected in some" "Endothelial cells: 5.7;Enteroendocrine cells: 4.3;Glial cells: 8.6;Neuronal cells: 17.7" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 19.8" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 11.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 6259636.9;Microglia and Neuropil: 8197580.2;Neurons: 6503078.4" "Tissue enriched" "Detected in single" 151836 "cerebral cortex: 15183633.4" HPA055915 Uncertain Approved "Vesicles,Microtubules,Primary cilium,Primary cilium tip,Basal body" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 1 "Vesicles, Primary cilium" "Microtubules, Primary cilium tip, Basal body" "HPA055915: " "unprognostic (1.91e-1)" "unprognostic (1.41e-3)" "unprognostic (6.91e-3)" "unprognostic (8.52e-2)" "potential prognostic favorable (3.92e-5)" "unprognostic (1.24e-1)" "unprognostic (1.46e-1)" "unprognostic (1.23e-1)" "unprognostic (6.01e-2)" "unprognostic (5.87e-2)" C2CD6 "ALS2CR11, FLJ25351" ENSG00000155754 "C2 calcium dependent domain containing 6" Q53TS8 2 201487421-201619178 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "testis: 37.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 104.2;Choroid plexus epithelial cells: 73.3;Early spermatids: 267.9;Late primary spermatocytes: 399.1;Late spermatids: 289.6;Rod photoreceptor cells: 78.2;Somatotrophs: 155.5;Thyrotrophs: 87.0" "Cell type enhanced" "Detected in many" "Myocytes: 104.2;Pituitary endocrine cells: 155.5;Spermatogenic cell types: 399.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 96.8" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Adrenocortical cancer: 7.8" "Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 137 "Neurons: 13742.2" "Tissue enriched" "Detected in many" "lymphoid tissue: 4756921.9" HPA045406 Approved "Acrosome,Equatorial segment,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 44 "Principal piece" "Acrosome, Equatorial segment" "HPA045406: " "unprognostic (4.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.67e-2)" "unprognostic (4.43e-2)" "unprognostic (3.75e-2)" C2orf16 DKFZp434G118 ENSG00000221843 "Chromosome 2 open reading frame 16" 2 27537386-27582722 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "testis: 10.1" "Cell type enriched" "Detected in some" 4 "Early spermatids: 476.0" "Cell type enriched" "Detected in some" 101 "Spermatogenic cell types: 476.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052136, HPA056962" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 79: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA052136: , HPA056962: " "unprognostic (9.42e-2)" "potential prognostic favorable (5.23e-4)" C2orf68 ENSG00000168887 "Chromosome 2 open reading frame 68" Q2NKX9 2 85605254-85612066 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "ovary: 1248732.5" HPA051143 Uncertain Approved "Nucleoplasm,Nuclear membrane,Nucleoli,Mitochondria" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 11 "Nucleoplasm, Nuclear membrane, Mitochondria" Nucleoli "HPA051143: " "unprognostic (1.40e-2)" "unprognostic (5.65e-2)" "unprognostic (9.18e-2)" "unprognostic (3.75e-1)" "unprognostic (2.31e-3)" "unprognostic (3.17e-1)" "unprognostic (2.34e-1)" "unprognostic (1.45e-3)" "unprognostic (1.28e-1)" "unprognostic (2.98e-1)" "unprognostic (1.45e-2)" "unprognostic (1.78e-1)" "unprognostic (3.60e-1)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (2.01e-3)" "unprognostic (2.28e-1)" "unprognostic (2.74e-1)" "unprognostic (9.90e-3)" "unprognostic (1.70e-2)" "unprognostic (3.44e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (1.85e-2)" "unprognostic (9.93e-2)" "unprognostic (6.72e-3)" "unprognostic (4.75e-2)" "unprognostic (6.22e-2)" "unprognostic (1.63e-1)" "unprognostic (1.20e-1)" "unprognostic (6.55e-2)" "unprognostic (1.81e-1)" C2orf76 "AIM29, LOC130355, MGC104437" ENSG00000186132 "Chromosome 2 open reading frame 76" Q3KRA6 2 119302225-119366834 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 175.0" "Cell type enhanced" "Detected in all" "Oocytes: 175.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 46 "Collecting ducts: 2504.4;Oocytes: 3107.4;Pancreas epithelial cells: 8212.0" "Tissue enhanced" "Detected in many" "Stomach: 2514395.1" "HPA044977, HPA055362" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" "Endoplasmic reticulum" "HPA044977: , HPA055362: " "unprognostic (1.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-1)" "unprognostic (1.65e-2)" "unprognostic (5.97e-2)" "unprognostic (4.30e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (5.73e-2)" "unprognostic (2.22e-1)" "unprognostic (1.26e-1)" "unprognostic (1.34e-3)" "unprognostic (3.80e-3)" "unprognostic (6.80e-2)" "unprognostic (4.81e-1)" "unprognostic (7.96e-3)" "unprognostic (6.57e-2)" "unprognostic (7.40e-2)" "unprognostic (1.13e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (6.34e-5)" "unprognostic (6.02e-2)" "unprognostic (2.02e-1)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (7.21e-4)" "unprognostic (6.13e-2)" "unprognostic (2.59e-2)" "unprognostic (4.08e-1)" "unprognostic (4.44e-1)" C3orf18 G20 ENSG00000088543 "Chromosome 3 open reading frame 18" Q9UK00 3 50558025-50571027 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.9" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 53.3;Early spermatids: 65.3;Late spermatids: 105.4" "Group enriched" "Detected in many" 5 "Myocytes: 53.3;Spermatogenic cell types: 105.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 35.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 2.2;NK-cells: 2.0;T-cells: 6.3" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Group enriched" "Detected in all" 4 "cerebellum: 28.2;olfactory bulb: 27.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA012105 Approved Approved Cytosol No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 11 Cytosol "HPA012105: " "unprognostic (3.86e-2)" "unprognostic (4.22e-2)" "potential prognostic favorable (7.46e-4)" "unprognostic (2.31e-2)" "unprognostic (1.50e-2)" "unprognostic (2.51e-2)" "unprognostic (5.68e-2)" "unprognostic (3.24e-2)" "unprognostic (3.83e-1)" "unprognostic (6.88e-2)" "unprognostic (2.41e-3)" "unprognostic (1.80e-1)" "potential prognostic favorable (3.59e-5)" "unprognostic (1.44e-1)" "unprognostic (3.79e-2)" "potential prognostic favorable (3.24e-4)" "unprognostic (1.64e-1)" "unprognostic (2.17e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (2.80e-2)" "unprognostic (2.82e-3)" "unprognostic (3.74e-1)" "unprognostic (6.12e-2)" "unprognostic (3.48e-2)" "unprognostic (2.30e-1)" "unprognostic (6.38e-2)" "unprognostic (1.47e-2)" "unprognostic (3.35e-1)" "unprognostic (3.32e-1)" "unprognostic (6.05e-2)" C4BPB C4BP ENSG00000123843 "Complement component 4 binding protein beta" P20851 1 207088860-207099993 "Human disease related genes, Plasma proteins, Predicted secreted proteins" "Complement pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 440.2" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 685.8" "Cell type enriched" "Detected in many" 9 "Hepatocytes: 685.8" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in many" 21 "Liver Hepatocellular Carcinoma (TCGA): 320.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bile duct cancer: 39.5" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Alveolar cell types: 14573920.8" "Low tissue specificity" "Detected in many" "HPA000925, HPA051620" Approved Uncertain "Golgi apparatus" "Secreted to blood" "Complement pathway" NA NA 265000000000 1900000000 "Cluster 30: Non-specific - DNA binding" "Cluster 53: Liver - Plasma proteins" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 "Golgi apparatus" "HPA000925: , HPA051620: " "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-1)" "unprognostic (1.85e-1)" "unprognostic (3.37e-1)" "unprognostic (1.48e-1)" "unprognostic (2.67e-3)" "unprognostic (1.32e-2)" "unprognostic (4.88e-3)" "unprognostic (7.85e-2)" "unprognostic (2.46e-2)" "unprognostic (2.60e-2)" "unprognostic (3.84e-2)" "unprognostic (2.96e-1)" "unprognostic (2.29e-2)" "unprognostic (2.92e-1)" "unprognostic (3.22e-1)" C4orf47 LOC441054 ENSG00000205129 "Chromosome 4 open reading frame 47" A7E2U8 4 185426249-185449826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 29.9;fallopian tube: 11.0;retina: 12.5;testis: 10.9" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 309.7;Cone photoreceptor cells: 138.7;Early spermatids: 194.1;Endometrial ciliated cells: 227.3;Ependymal cells: 545.8;Epididymal efferent duct ciliated cells: 526.3;Fallopian tube ciliated cells: 417.8;Late primary spermatocytes: 261.3;Oocytes: 170.4;Respiratory ciliated cells: 511.9;Rod photoreceptor cells: 226.8" "Group enriched" "Detected in many" 5 "Ciliated cells: 545.8;Neuronal cells: 226.8;Oocytes: 170.4;Spermatogenic cell types: 261.3" "Group enriched" "Detected in all" 5 "choroid plexus epithelial cell: 384.3;ependymal cell: 668.6" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.9" "Region enhanced" "Detected in all" "choroid plexus: 48.2" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13149 "Fallopian tube cells: 1314948.6" "Tissue enriched" "Detected in single" 96542 "fallopian tube: 9654197.0" HPA063485 Enhanced Approved "Principal piece,End piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Principal piece, End piece" "HPA063485: " "unprognostic (4.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.21e-2)" "unprognostic (1.49e-2)" "unprognostic (1.99e-2)" "unprognostic (5.42e-2)" "unprognostic (5.68e-2)" "unprognostic (4.52e-3)" "unprognostic (2.63e-1)" "unprognostic (4.08e-3)" "unprognostic (2.44e-1)" "unprognostic (2.48e-1)" "unprognostic (2.56e-1)" "unprognostic (1.01e-1)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (8.31e-2)" "unprognostic (1.96e-2)" "unprognostic (2.23e-1)" C5orf58 ENSG00000234511 "Chromosome 5 open reading frame 58" C9J3I9 5 170229104-170252575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 31 "testis: 201.0" "Group enriched" "Detected in some" 9 "Early primary spermatocytes: 1120.6;Late primary spermatocytes: 1046.9;Oocytes: 308.5" "Group enriched" "Detected in many" 36 "Oocytes: 308.5;Spermatogenic cell types: 1120.6" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.7;fibroblast: 2.7;leukocyte: 2.4" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 9.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 8.1" "Kidney - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - Macrophages, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA052795 Approved "Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 57: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" "Centriolar satellite" "Cytokinetic bridge, Cytosol" "HPA052795: " "unprognostic (1.17e-2)" "unprognostic (7.51e-2)" "unprognostic (5.59e-2)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.68e-1)" "unprognostic (9.90e-2)" "unprognostic (8.43e-3)" "unprognostic (3.13e-2)" "unprognostic (1.14e-2)" "unprognostic (2.26e-3)" "unprognostic (1.40e-1)" "unprognostic (1.35e-1)" C6orf52 ENSG00000137434 "Chromosome 6 open reading frame 52" Q5T4I8 6 10671418-10694797 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 13.1" "Cell type enriched" "Detected in many" 16 "Oocytes: 1243.4" "Cell type enriched" "Detected in many" 16 "Oocytes: 1243.4" "Cell type enhanced" "Detected in many" "ependymal cell: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 2.7;T-reg: 4.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.7;T-cells: 4.2" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4209 "Oocytes: 420856.4" "Not detected" "Not detected" HPA051142 Uncertain Approved "Nuclear speckles,Intermediate filaments" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 67: Testis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 23: Non-specific - Transcription" "Cluster 41: Oocytes - Oogenesis" "Nuclear speckles" "Intermediate filaments" "HPA051142: " "unprognostic (6.18e-2)" "unprognostic (1.23e-2)" "unprognostic (4.60e-2)" "unprognostic (4.29e-3)" "unprognostic (2.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.73e-1)" "unprognostic (2.52e-2)" "unprognostic (9.55e-2)" "unprognostic (1.64e-1)" "unprognostic (1.66e-2)" "unprognostic (4.39e-2)" "unprognostic (8.22e-3)" "unprognostic (1.15e-1)" "unprognostic (1.26e-1)" "unprognostic (8.86e-3)" "unprognostic (5.87e-2)" "unprognostic (1.74e-1)" C7orf33 ENSG00000170279 "Chromosome 7 open reading frame 33" Q8WU49 7 148590766-148615860 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 6 "retina: 1.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 49.7;Early spermatids: 7.5;Extravillous trophoblasts: 17.7;Late spermatids: 9.0;Migrating cytotrophoblasts: 6.1;Myonuclei: 3.7;Rod photoreceptor cells: 2.9" "Cell type enhanced" "Detected in some" "Neuronal cells: 49.7;Spermatogenic cell types: 9.0;Trophoblast cells: 17.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 6 "lymphoma: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA047587 Approved "Acrosome,Equatorial segment" NA NA "Cluster 42: Retina - Visual perception" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Acrosome, Equatorial segment" "HPA047587: " C7orf50 "MGC11257, YCR016W" ENSG00000146540 "Chromosome 7 open reading frame 50" Q9BRJ6 7 996986-1138260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 11805090.3" "Tissue enhanced" "Detected in many" "intestine: 8139200.3" HPA052281 Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 67: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 60 "Nucleoplasm, Nucleoli" "HPA052281: " "unprognostic (4.23e-2)" "unprognostic (2.56e-1)" "unprognostic (2.50e-1)" "unprognostic (1.44e-2)" "unprognostic (3.06e-2)" "unprognostic (1.76e-1)" "unprognostic (4.28e-3)" "unprognostic (2.60e-2)" "unprognostic (1.51e-3)" "unprognostic (7.65e-3)" "unprognostic (3.86e-2)" "unprognostic (2.15e-1)" "unprognostic (4.91e-3)" "validated prognostic unfavorable (5.40e-4)" "validated prognostic unfavorable (6.30e-4)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (2.25e-1)" "unprognostic (1.63e-1)" "unprognostic (6.47e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (4.96e-4)" "unprognostic (1.80e-2)" "unprognostic (8.94e-2)" "unprognostic (2.50e-1)" "unprognostic (7.44e-2)" "unprognostic (5.60e-2)" "unprognostic (1.99e-2)" "unprognostic (1.45e-1)" "unprognostic (2.24e-1)" "unprognostic (2.35e-2)" C7orf57 ENSG00000164746 "Chromosome 7 open reading frame 57" Q8NEG2 7 48035511-48061304 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.4;fallopian tube: 13.1" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 41.5;Endometrial ciliated cells: 80.2;Ependymal cells: 137.5;Epididymal efferent duct ciliated cells: 107.9;Esophageal apical cells: 30.2;Fallopian tube ciliated cells: 149.7;Late primary spermatocytes: 36.8;Respiratory ciliated cells: 225.2;Respiratory deuterosomal cells: 46.6" "Cell type enriched" "Detected in some" 6 "Ciliated cells: 225.2" "Cell type enriched" "Detected in many" 4 "ependymal cell: 162.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 6.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 42172 "Fallopian tube cells: 4217168.9" "Tissue enriched" "Detected in single" 16036 "fallopian tube: 1603551.0" HPA021286 Enhanced Approved "Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 107: Ciliated cells - Cilia assembly & function" Cytosol "Primary cilium, Primary cilium transition zone, Basal body" "HPA021286: " "unprognostic (1.18e-1)" "potential prognostic favorable (8.81e-4)" "unprognostic (1.37e-2)" "unprognostic (7.95e-3)" "unprognostic (6.28e-2)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (2.30e-4)" "unprognostic (7.60e-2)" "unprognostic (3.73e-2)" C8orf34 "vest-1, VEST1" ENSG00000165084 "Chromosome 8 open reading frame 34" Q49A92 8 68330955-68819023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 8.6;parathyroid gland: 6.9" "Cell type enhanced" "Detected in many" "Adipocytes: 210.7;Alveolar cells type 2: 306.1;Brain excitatory neurons: 271.6;Brain inhibitory neurons: 234.6;Endometrial ciliated cells: 450.0;Ependymal cells: 2521.4;Fallopian tube ciliated cells: 446.6;Respiratory ciliated cells: 961.8;Thyrotrophs: 227.3;Transitional alveolar cells: 374.0" "Cell type enriched" "Detected in many" 6 "Ciliated cells: 2521.4" "Cell type enhanced" "Detected in all" "ependymal cell: 2549.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 92 "cerebral cortex: 9152.2" "HPA044420, HPA053065" Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA044420: , HPA053065: " "unprognostic (3.66e-2)" "unprognostic (6.14e-2)" "unprognostic (2.44e-1)" "unprognostic (1.98e-1)" "unprognostic (1.72e-2)" "unprognostic (1.71e-1)" "unprognostic (1.63e-3)" "unprognostic (1.50e-1)" "unprognostic (9.46e-2)" "unprognostic (1.88e-2)" "unprognostic (3.91e-2)" "unprognostic (2.46e-2)" "unprognostic (1.73e-1)" "unprognostic (2.26e-1)" "unprognostic (1.48e-2)" C8orf58 FLJ34715 ENSG00000241852 "Chromosome 8 open reading frame 58" Q8NAV2 8 22599599-22604150 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 16.4;Cytotrophoblasts: 28.3;Decidual stromal cells: 18.8;Extravillous trophoblasts: 41.1;Migrating cytotrophoblasts: 43.9;Podocytes: 25.6;Syncytiotrophoblasts: 62.3" "Cell type enhanced" "Detected in many" "Renal nephron cells: 25.6;Trophoblast cells: 62.3" "Cell type enhanced" "Detected in many" "pericyte: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 615 "Glomeruli: 61523.9" "Not detected" "Not detected" "HPA024667, HPA028286" Uncertain Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Nuclear bodies" Nucleoplasm "HPA024667: , HPA028286: " "unprognostic (6.95e-3)" "unprognostic (2.01e-2)" "potential prognostic favorable (8.72e-4)" "unprognostic (7.23e-2)" "unprognostic (1.47e-2)" "unprognostic (1.29e-1)" "unprognostic (1.71e-2)" "unprognostic (2.81e-1)" "unprognostic (3.26e-1)" "unprognostic (3.43e-1)" "unprognostic (5.37e-2)" "unprognostic (1.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.01e-1)" "unprognostic (4.03e-2)" "unprognostic (2.16e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-1)" "unprognostic (4.00e-1)" "unprognostic (3.36e-2)" "unprognostic (6.01e-2)" "unprognostic (7.15e-2)" "unprognostic (4.88e-3)" "unprognostic (5.19e-2)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (2.57e-1)" "unprognostic (2.19e-1)" "unprognostic (1.62e-1)" "unprognostic (6.53e-2)" "unprognostic (2.36e-2)" C9orf153 bA507D14.1 ENSG00000187753 "Chromosome 9 open reading frame 153" Q5TBE3 9 86220265-86259657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 19.2" "Group enriched" "Detected in many" 12 "Early spermatids: 679.5;Late primary spermatocytes: 261.2;Late spermatids: 503.1" "Cell type enriched" "Detected in many" 17 "Spermatogenic cell types: 679.5" "Cell type enhanced" "Detected in all" "pericyte: 40.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.6" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA079466 Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Nuclear bodies, Plasma membrane" "Nucleoplasm, Vesicles" "HPA079466: " "unprognostic (4.28e-2)" "unprognostic (3.79e-2)" "unprognostic (4.01e-2)" "unprognostic (5.98e-2)" C9orf24 "bA573M23.4, CBE1, MGC32921, MGC33614, NYD-SP22, SMRP1" ENSG00000164972 "Chromosome 9 open reading frame 24" Q8NCR6 9 34379019-34397828 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 60.7;choroid plexus: 226.2;fallopian tube: 102.1;testis: 73.9" "Cell type enhanced" "Detected in many" "Early spermatids: 860.7;Endometrial ciliated cells: 889.5;Epididymal efferent duct ciliated cells: 1288.1;Fallopian tube ciliated cells: 2177.7;Late spermatids: 4568.5;Respiratory ciliated cells: 1668.5" "Group enriched" "Detected in many" 26 "Ciliated cells: 2177.7;Spermatogenic cell types: 4568.5" "Group enriched" "Detected in all" 6 "choroid plexus epithelial cell: 93.3;ependymal cell: 273.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 24.7;Uterine Corpus Endometrial Carcinoma (TCGA): 33.8" "Region enhanced" "Detected in all" "choroid plexus: 204.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4080 "Fallopian tube cells: 407974.9" "Tissue enriched" "Detected in single" 1078 "fallopian tube: 107778.7" HPA053008 Enhanced Supported "Nucleoplasm,Cytosol,Equatorial segment,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 24 "Nucleoplasm, Principal piece" "Cytosol, Equatorial segment" "HPA053008: " "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "potential prognostic favorable (1.38e-4)" "unprognostic (1.72e-1)" "unprognostic (8.25e-2)" "unprognostic (1.25e-2)" "unprognostic (1.02e-1)" "unprognostic (3.45e-2)" "unprognostic (9.64e-2)" "unprognostic (3.20e-1)" "unprognostic (6.29e-2)" "unprognostic (7.34e-2)" "unprognostic (1.28e-1)" "unprognostic (5.82e-2)" "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (2.16e-3)" "potential prognostic favorable (2.50e-4)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (6.41e-2)" "unprognostic (5.71e-2)" "unprognostic (2.36e-2)" "unprognostic (7.41e-2)" C9orf72 "DENND9, DENNL72, MGC23980" ENSG00000147894 "C9orf72-SMCR8 complex subunit" Q96LT7 9 27535640-27573866 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Guanine-nucleotide releasing factor" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 333.9;Kupffer cells: 297.2;monocytes: 528.2;Neutrophils: 1758.9" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 528.2;Neutrophils: 1758.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 7 "basophil: 24.3;classical monocyte: 32.0;intermediate monocyte: 44.8;myeloid DC: 25.2;neutrophil: 34.5;non-classical monocyte: 37.0" "Group enriched" "Detected in all" 8 "dendritic cells: 25.2;granulocytes: 34.5;monocytes: 44.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "Stomach: 1050594.4" HPA023873 Uncertain Supported "Vesicles,Midbody ring,Cytosol" "Intracellular and membrane" Other Yes NA "Cluster 40: Monocytes - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 25: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 42 "Vesicles, Cytosol" "Midbody ring" "HPA023873: " "unprognostic (1.87e-1)" "unprognostic (3.61e-2)" "unprognostic (2.32e-1)" "unprognostic (3.03e-1)" "unprognostic (3.13e-1)" "unprognostic (2.74e-2)" "unprognostic (6.19e-3)" "unprognostic (2.99e-2)" "unprognostic (8.69e-3)" "unprognostic (1.25e-1)" "unprognostic (3.27e-2)" "unprognostic (2.93e-2)" "unprognostic (1.10e-2)" "unprognostic (3.05e-1)" "unprognostic (7.83e-2)" "unprognostic (4.96e-2)" "unprognostic (3.11e-2)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "unprognostic (2.63e-1)" "unprognostic (2.90e-1)" "unprognostic (2.45e-2)" "unprognostic (1.31e-2)" "unprognostic (2.20e-1)" "unprognostic (2.71e-2)" "unprognostic (3.15e-2)" "unprognostic (2.12e-1)" "unprognostic (3.23e-2)" "unprognostic (3.24e-1)" "unprognostic (2.06e-2)" "unprognostic (1.90e-1)" C9orf78 "CSU2, HCA59, HSPC220" ENSG00000136819 "Chromosome 9 open reading frame 78" Q9NZ63 9 129827290-129835863 "Predicted intracellular proteins" "Chromosome partition, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal clear cells: 338.9;Erythrocytes: 275.1" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 338.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "T-cells: 3072212.1" "Tissue enhanced" "Detected in many" "lymphoid tissue: 3695341.1;ovary: 2528755.8" "HPA021216, HPA021232, HPA021242" Enhanced Enhanced Nucleoplasm No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Nucleoplasm "HPA021216: , HPA021232: , HPA021242: " "unprognostic (9.90e-2)" "unprognostic (1.14e-2)" "unprognostic (9.85e-2)" "unprognostic (1.29e-1)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (7.24e-2)" "unprognostic (4.79e-3)" "unprognostic (1.99e-1)" "unprognostic (9.04e-2)" "validated prognostic favorable (2.56e-4)" "validated prognostic favorable (9.57e-4)" "unprognostic (8.44e-3)" "unprognostic (6.78e-2)" "unprognostic (4.76e-2)" "unprognostic (9.34e-2)" "unprognostic (5.44e-2)" "unprognostic (1.41e-1)" "unprognostic (2.68e-2)" "unprognostic (2.16e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (1.43e-3)" "unprognostic (1.50e-1)" "unprognostic (3.29e-2)" "unprognostic (1.18e-1)" "unprognostic (5.61e-1)" "unprognostic (8.52e-3)" "unprognostic (1.51e-1)" "potential prognostic favorable (8.32e-4)" C9orf85 MGC61599 ENSG00000155621 "Chromosome 9 open reading frame 85" Q96MD7 9 71911510-71986054 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050767, HPA076627" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" "Golgi apparatus" "Nucleoplasm, Nucleoli" "HPA050767: , HPA076627: " "unprognostic (4.84e-2)" "unprognostic (3.31e-2)" "unprognostic (2.93e-3)" "unprognostic (4.30e-1)" "unprognostic (1.36e-1)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (5.72e-4)" "unprognostic (7.25e-2)" "unprognostic (4.49e-2)" "validated prognostic favorable (3.07e-4)" "validated prognostic favorable (4.95e-4)" "unprognostic (5.95e-2)" "potential prognostic unfavorable (1.75e-5)" "unprognostic (2.00e-2)" "unprognostic (1.77e-1)" "unprognostic (1.15e-1)" "unprognostic (8.31e-2)" "unprognostic (1.67e-1)" "unprognostic (2.57e-1)" "unprognostic (1.73e-1)" "unprognostic (3.76e-2)" "unprognostic (7.49e-2)" "unprognostic (2.42e-1)" "unprognostic (7.89e-3)" "unprognostic (1.55e-2)" "unprognostic (5.12e-2)" "unprognostic (8.54e-2)" "unprognostic (6.69e-2)" "unprognostic (2.46e-2)" "unprognostic (3.57e-1)" CA13 "CAXIII, FLJ37995, MGC59868" ENSG00000185015 "Carbonic anhydrase 13" Q8N1Q1 8 85220587-85284073 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.8" "Cell type enhanced" "Detected in many" "Enterocytes: 157.4" "Cell type enhanced" "Detected in all" "Enterocytes: 157.4" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 129.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Large ducts: 7028281.0" "Low tissue specificity" "Detected in many" "HPA024689, CAB025567" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles NA NA 170000 "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 Nucleoli "Nucleoplasm, Vesicles" "CAB025567: , HPA024689: " "unprognostic (1.40e-3)" "unprognostic (1.45e-2)" "unprognostic (5.14e-2)" "unprognostic (1.06e-2)" "unprognostic (7.52e-2)" "unprognostic (1.66e-3)" "unprognostic (6.00e-2)" "unprognostic (9.69e-2)" "unprognostic (6.65e-2)" "unprognostic (1.55e-2)" "unprognostic (6.77e-3)" "unprognostic (1.05e-1)" "unprognostic (1.70e-1)" "unprognostic (9.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.02e-2)" "unprognostic (6.94e-2)" "unprognostic (3.29e-1)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (1.06e-2)" "unprognostic (3.22e-1)" "unprognostic (2.53e-1)" "unprognostic (5.16e-2)" "unprognostic (7.39e-2)" "unprognostic (2.90e-1)" "unprognostic (8.08e-2)" "unprognostic (2.73e-2)" "unprognostic (1.36e-1)" "unprognostic (1.23e-1)" CA5B ENSG00000169239 "Carbonic anhydrase 5B" Q9Y2D0 X 15688830-15788411 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 3416429.0;T-cells: 5930814.3" "Low tissue specificity" "Detected in many" HPA012618 Uncertain Supported Mitochondria NA NA "Cluster 1: T-cells - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 1 Mitochondria "HPA012618: " "unprognostic (7.42e-2)" "unprognostic (1.71e-3)" "unprognostic (2.74e-1)" "unprognostic (6.20e-2)" "unprognostic (2.88e-1)" "unprognostic (2.58e-2)" "unprognostic (4.81e-3)" "potential prognostic unfavorable (6.88e-4)" "unprognostic (9.42e-3)" "unprognostic (3.81e-2)" "potential prognostic favorable (1.60e-7)" "unprognostic (1.24e-3)" "unprognostic (3.75e-2)" "unprognostic (1.32e-1)" "unprognostic (2.21e-2)" "unprognostic (1.99e-3)" "unprognostic (2.17e-1)" "unprognostic (1.50e-1)" "unprognostic (2.94e-2)" "unprognostic (1.27e-2)" "unprognostic (1.74e-1)" "unprognostic (5.88e-2)" "unprognostic (3.04e-1)" "unprognostic (5.21e-1)" "unprognostic (1.81e-1)" "unprognostic (3.91e-3)" "unprognostic (4.05e-1)" "unprognostic (2.73e-1)" "unprognostic (1.84e-1)" "unprognostic (3.23e-2)" "unprognostic (4.28e-2)" CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673928-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "stomach 1: 293.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 54.5;Early spermatids: 334.7;Foveolar cells: 82.8;Gastric chief cells: 287.2;Late primary spermatocytes: 43.3;Mucous neck cells: 80.2;Pancreatic duct cells: 35.2;Parietal cells: 107.8" "Group enriched" "Detected in many" 5 "Gastric glandular cells: 287.2;Spermatogenic cell types: 334.7" "Cell type enriched" "Detected in some" 11 "upper rhombic lip: 12.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 219.1" "Region enriched" "Detected in some" 9 "cerebellum: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 114.9" "Adipose visceral - Mesothelial cells, Liver - Cholangiocytes, Prostate - Smooth muscle cells, Testis - Late spermatids" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1153 "Keratinocytes: 115250.8" "Tissue enriched" "Detected in some" "Stomach: 282652562.9" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" NA NA "Cluster 60: Stomach - Digestion" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 14 "Plasma membrane" "CAB005100: , CAB017107: , HPA055207: " "unprognostic (2.26e-2)" "unprognostic (3.73e-2)" "unprognostic (4.90e-1)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (1.70e-1)" "unprognostic (1.22e-2)" "unprognostic (2.80e-3)" "unprognostic (2.67e-1)" "unprognostic (3.99e-2)" "potential prognostic favorable (5.22e-8)" "unprognostic (3.45e-2)" "unprognostic (1.28e-2)" "validated prognostic unfavorable (5.71e-6)" "validated prognostic unfavorable (7.41e-4)" "unprognostic (2.38e-3)" "potential prognostic unfavorable (4.33e-5)" "unprognostic (3.49e-1)" "unprognostic (1.64e-1)" "unprognostic (3.82e-1)" "unprognostic (2.79e-1)" "unprognostic (1.89e-3)" "unprognostic (5.25e-3)" "unprognostic (8.55e-2)" "unprognostic (1.34e-3)" "unprognostic (1.00e-1)" "unprognostic (6.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.29e-1)" CABLES1 "FLJ35924, HsT2563" ENSG00000134508 "Cdk5 and Abl enzyme substrate 1" Q8TDN4 18 23134564-23260470 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 53.3" "Cell type enhanced" "Detected in many" "Astrocytes: 533.9;Bergmann glia: 481.9;Endometrial glandular cells: 1282.4;Endometrial luminal cells: 366.7;Hofbauer cells: 242.9;Melanocytes: 355.7" "Cell type enhanced" "Detected in many" "Glandular cells: 1282.4;Glial cells: 533.9" "Cell type enhanced" "Detected in all" "astrocyte: 528.5;Bergmann glia: 442.8" "Cancer enriched" "Detected in all" 5 "Skin Cutaneous Melanoma (TCGA): 99.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Prostate - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 741760.2" "Tissue enhanced" "Detected in many" "kidney: 1366336.7" HPA073649 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Secretory epithelial cells - Mixed function" 4 "Nucleoplasm, Nuclear bodies" "HPA073649: " "unprognostic (3.20e-1)" "unprognostic (8.73e-2)" "unprognostic (1.63e-1)" "unprognostic (2.57e-1)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (1.73e-1)" "potential prognostic favorable (1.37e-6)" "unprognostic (1.03e-3)" "unprognostic (3.59e-2)" "validated prognostic favorable (6.02e-11)" "validated prognostic favorable (3.72e-5)" "unprognostic (5.09e-3)" "unprognostic (1.93e-3)" "unprognostic (2.57e-2)" "unprognostic (1.01e-2)" "unprognostic (6.24e-3)" "unprognostic (1.14e-1)" "unprognostic (1.15e-1)" "unprognostic (6.39e-2)" "unprognostic (2.95e-1)" "unprognostic (4.02e-2)" "unprognostic (1.95e-1)" "unprognostic (1.82e-2)" "unprognostic (2.95e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "unprognostic (1.92e-1)" "unprognostic (4.66e-2)" "unprognostic (7.82e-2)" "unprognostic (3.86e-2)" CACHD1 "KIAA1573, VWCD1" ENSG00000158966 "Cache domain containing 1" Q5VU97 1 64470129-64693058 "Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 436.6;Astrocytes: 546.1;Bergmann glia: 601.9;Choroid plexus epithelial cells: 602.9;Ependymal cells: 396.3;Medullary thymic epithelial cells: 350.4;Mesothelial cells: 336.2;Pituicytes/FSCs: 417.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 602.9;Glial cells: 601.9" "Cell type enhanced" "Detected in all" "astrocyte: 655.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 32.6" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 2116239.3;Granulosa cells: 2650391.1" "Tissue enhanced" "Detected in some" "cerebral cortex: 2667683.6" HPA017202 Uncertain Uncertain Nucleoplasm,Nucleoli NA NA 240000 "Cluster 65: Brain - Transcription" "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Nucleoplasm, Nucleoli" "HPA017202: " "unprognostic (9.25e-2)" "unprognostic (1.99e-2)" "unprognostic (1.83e-1)" "unprognostic (1.39e-1)" "unprognostic (5.37e-2)" "unprognostic (5.51e-3)" "unprognostic (3.79e-1)" "unprognostic (2.58e-2)" "unprognostic (1.67e-1)" "unprognostic (7.43e-2)" "potential prognostic favorable (1.49e-5)" "unprognostic (1.65e-2)" "unprognostic (1.49e-3)" "unprognostic (6.76e-2)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (4.19e-1)" "unprognostic (1.50e-1)" "unprognostic (1.90e-2)" "unprognostic (5.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.79e-1)" "unprognostic (9.81e-2)" "unprognostic (7.82e-2)" "unprognostic (1.17e-2)" "unprognostic (1.42e-1)" "unprognostic (3.51e-1)" "unprognostic (2.47e-2)" "unprognostic (2.03e-1)" "unprognostic (1.94e-1)" "unprognostic (1.43e-1)" CACNA1B "CACNL1A5, CACNN, Cav2.2" ENSG00000148408 "Calcium voltage-gated channel subunit alpha1 B" Q00975 9 137877782-138124624 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.4;pituitary gland: 6.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 319.1;Brain excitatory neurons: 493.2;Brain inhibitory neurons: 541.2;Early primary spermatocytes: 154.5;Gonadotrophs: 248.0;Lactotrophs: 262.2;Other brain neurons: 515.8;Retinal amacrine cells: 584.2;Retinal ganglion cells: 641.2;Somatotrophs: 459.6;Thyrotrophs: 438.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 319.1;Neuronal cells: 641.2;Pituitary endocrine cells: 459.6;Spermatogenic cell types: 154.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 102681 "Astrocytes and Neuropil: 9477343.1;Microglia and Neuropil: 16923947.8;Neurons: 4402991.5" "Tissue enriched" "Detected in single" 154748 "cerebral cortex: 15474839.3" HPA044347 Uncertain Approved "Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 3 "Cytosol, Acrosome, Equatorial segment" "HPA044347: " "unprognostic (4.29e-2)" "unprognostic (5.93e-3)" "unprognostic (1.08e-2)" "unprognostic (1.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.57e-1)" CACNA1C "CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS" ENSG00000151067 "Calcium voltage-gated channel subunit alpha1 C" Q13936 12 1970772-2697950 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Host-virus interaction, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Brugada syndrome, Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 25.0" "Cell type enhanced" "Detected in some" "Astrocytes: 180.2;Bergmann glia: 163.4;Brain excitatory neurons: 661.1;Brain inhibitory neurons: 711.5;Choroid plexus epithelial cells: 147.0;Oligodendrocyte progenitor cells: 284.3;Other brain neurons: 504.7;Pericytes: 220.8;Vascular smooth muscle cells: 464.1" "Cell type enhanced" "Detected in many" "Glial cells: 284.3;Mural cells: 464.1;Neuronal cells: 711.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.9" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Capillaries: 16658493.6;Cardiomyocytes: 12731246.0" "Tissue enriched" "Detected in some" "intestine: 2430111.7" "HPA039796, CAB079031" Enhanced Approved Approved "Nucleoplasm,Plasma membrane,Primary cilium" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 105: Non-specific - Mixed function" 27 "Nucleoplasm, Plasma membrane" "Primary cilium" "CAB079031: , HPA039796: " "unprognostic (3.73e-2)" "unprognostic (9.56e-2)" "unprognostic (7.20e-2)" "unprognostic (8.22e-2)" "unprognostic (1.22e-3)" "validated prognostic favorable (1.04e-4)" "validated prognostic favorable (4.50e-4)" "unprognostic (3.90e-1)" "unprognostic (2.10e-2)" "unprognostic (1.43e-2)" "unprognostic (2.39e-1)" "unprognostic (6.39e-2)" "unprognostic (8.77e-3)" "unprognostic (2.07e-2)" "unprognostic (1.10e-1)" CACNA1D "CACH3, CACN4, CACNL1A2, Cav1.3, CCHL1A2" ENSG00000157388 "Calcium voltage-gated channel subunit alpha1 D" Q01668 3 53328963-53813733 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Cancer-related genes, Deafness, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 859.0;Adrenal medulla cells: 574.4;Brain inhibitory neurons: 485.7;Corticotrophs: 671.0;Distal convoluted tubule cells: 583.3;Lactotrophs: 420.6;Microglia: 398.6;Pancreatic islet cells: 487.9;Retinal amacrine cells: 727.2;Retinal pigment epithelial cells: 716.2;Somatotrophs: 602.0;Thyrotrophs: 1007.0" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 859.0;Neuronal cells: 727.2;Pigment cells: 716.2;Pituitary endocrine cells: 1007.0;Renal nephron cells: 583.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "basophil: 3.7" "Lineage enriched" "Detected in single" 20 "granulocytes: 3.7" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Skeletal muscle - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 76 "Proximal tubules: 7610.1" "Not detected" "Not detected" HPA020215 Uncertain Approved "Nuclear membrane" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 22: Epididymis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" "Nuclear membrane" "HPA020215: " "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (2.50e-2)" "unprognostic (3.32e-2)" "unprognostic (8.32e-2)" "unprognostic (7.08e-3)" "unprognostic (2.66e-1)" "potential prognostic favorable (1.69e-8)" "unprognostic (3.49e-3)" "unprognostic (1.34e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-3)" "unprognostic (6.70e-2)" "unprognostic (7.68e-2)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (1.06e-2)" "unprognostic (1.29e-2)" "unprognostic (2.74e-1)" "unprognostic (5.70e-2)" CACNA1G "Cav3.1, NBR13" ENSG00000006283 "Calcium voltage-gated channel subunit alpha1 G" O43497 17 50560715-50627474 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 19.3;cervix: 8.2;retina: 8.0" "Group enriched" "Detected in some" 4 "Retinal amacrine cells: 132.3;Retinal bipolar cells: 187.8" "Cell type enriched" "Detected in many" 7 "Neuronal cells: 187.8" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 132.5;thalamic excitatory: 98.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.8;Testicular Germ Cell Tumor (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 6.8" "Lung - Fibroblasts_2, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13 "Microglia and Neuropil: 1328.6" "Tissue enriched" "Detected in single" 11606 "kidney: 1160617.7" HPA004714 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol,Acrosome,Equatorial segment,Perinuclear theca" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Acrosome, Equatorial segment, Perinuclear theca" "Nuclear bodies, Cytosol" "HPA004714: " "unprognostic (2.08e-1)" "unprognostic (2.02e-1)" "unprognostic (3.20e-2)" "unprognostic (2.05e-1)" "unprognostic (5.70e-2)" "unprognostic (4.51e-2)" CACNA1I Cav3.3 ENSG00000100346 "Calcium voltage-gated channel subunit alpha1 I" Q9P0X4 22 39570753-39689735 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;thyroid gland: 5.1" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 8.0;Brain excitatory neurons: 26.4;Brain inhibitory neurons: 23.8;Other brain neurons: 11.4;Retinal amacrine cells: 107.2;Retinal bipolar cells: 33.3;Thymic myoid cells: 8.2" "Cell type enriched" "Detected in some" 13 "Neuronal cells: 107.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 5 "Thyroid Carcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 2.8;Rhabdoid: 1.3" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7343 "Microglia and Neuropil: 1128461.5;Neurons: 340202.8" "Tissue enriched" "Detected in single" 8314 "cerebral cortex: 831378.9" HPA066992 Approved "Plasma membrane,Cell Junctions,Acrosome" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane" "Cell Junctions, Acrosome" "HPA066992: " "unprognostic (1.71e-1)" "unprognostic (1.64e-2)" CACNA1S "CACNL1A3, Cav1.1, HOKPP, hypoPP, MHS5" ENSG00000081248 "Calcium voltage-gated channel subunit alpha1 S" Q13698 1 201039512-201112451 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Ion channel, Voltage-gated channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 85 "skeletal muscle: 238.7;tongue: 180.4" "Cell type enriched" "Detected in some" 11 "Myonuclei: 437.2" "Cell type enriched" "Detected in some" 11 "Myocytes: 437.2" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 5.7" "Cancer enriched" "Detected in single" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 1.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.1" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 1.8" "Region enriched" "Detected in single" 5 "olfactory bulb: 3.8" "Cell type enriched" "Detected in single" 346211 "Skeletal myofibers: 34621050.2" "Tissue enriched" "Detected in single" 20049 "skeletal muscle: 2004892.1" "CAB009507, HPA048892, HPA056815" Enhanced Approved "Acrosome,Equatorial segment" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 "Acrosome, Equatorial segment" "CAB009507: , HPA048892: , HPA056815: " "unprognostic (1.22e-2)" CACNA2D2 "alpha2delta-2, KIAA0558" ENSG00000007402 "Calcium voltage-gated channel auxiliary subunit alpha2delta 2" Q9NY47 3 50362613-50504244 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 46.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 82.0;Alveolar cells type 2: 298.6;Brain inhibitory neurons: 51.6;Corticotrophs: 95.8;Oocytes: 110.5;Other brain neurons: 62.7;Pancreatic islet cells: 51.0;Retinal amacrine cells: 169.8;Transitional alveolar cells: 96.3;Tuft cells: 46.1" "Cell type enhanced" "Detected in many" "Alveolar cells: 298.6;Neuronal cells: 169.8;Oocytes: 110.5;Pituitary endocrine cells: 95.8" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 112.6" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 25.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 26.8;thyroid cancer: 13.2" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Kidney - Macrophages, Lung - Alveolar cells type 2, Pancreas - Alpha cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 24159660.4;Pancreatic islets: 39605634.6" "Tissue enhanced" "Detected in many" "cerebral cortex: 29483701.3" HPA034771 Enhanced Approved "Plasma membrane,Cytosol,Flagellar centriole,Mid piece" NA NA 1400000 "Cluster 11: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 81: Alveolar cells - Lung function" 1 Cytosol "Plasma membrane, Flagellar centriole, Mid piece" "HPA034771: " "unprognostic (3.86e-1)" "unprognostic (1.61e-1)" "unprognostic (1.02e-2)" "unprognostic (2.63e-2)" "unprognostic (1.05e-1)" "unprognostic (3.13e-2)" "unprognostic (2.66e-2)" "potential prognostic favorable (1.21e-4)" "unprognostic (2.36e-3)" "unprognostic (6.71e-3)" "unprognostic (1.45e-1)" "unprognostic (2.14e-1)" "unprognostic (2.16e-1)" "potential prognostic favorable (2.42e-4)" "unprognostic (2.83e-1)" "unprognostic (2.50e-1)" "unprognostic (2.19e-2)" "unprognostic (2.67e-2)" "unprognostic (2.18e-1)" "unprognostic (5.44e-2)" "unprognostic (2.64e-1)" "unprognostic (5.68e-3)" CACNA2D4 alpha2delta-4 ENSG00000151062 "Calcium voltage-gated channel auxiliary subunit alpha2delta 4" Q7Z3S7 12 1791963-1918666 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 39 "retina: 18.7" "Group enriched" "Detected in some" 7 "Early spermatids: 51.5;Late spermatids: 124.1" "Cell type enriched" "Detected in some" 10 "Spermatogenic cell types: 124.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 6.1;hippocampal dentate gyrus: 11.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 2.9;monocytes: 4.4;T-cells: 4.2" "Group enriched" "Detected in some" 4 "Leukemia: 7.5;lymphoma: 3.1;Sarcoma: 2.9" "Adrenal gland - Macrophages, Kidney - Fibroblasts, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Neurons: 265858.6;Smooth muscle cells: 146196.1" "Group enriched" "Detected in some" 18854 "intestine: 828284.6;pancreas: 2942608.0" HPA031952 Uncertain Approved "Mid piece,Principal piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 42: Retina - Visual perception" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Mid piece, Principal piece" "HPA031952: " "unprognostic (1.31e-1)" "unprognostic (2.12e-1)" "unprognostic (7.25e-2)" "unprognostic (1.48e-2)" "unprognostic (2.80e-1)" "unprognostic (1.19e-2)" CAD GATD4 ENSG00000084774 "Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase" P27708 2 27217369-27243943 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Allosteric enzyme, Hydrolase, Ligase, Multifunctional enzyme, Transferase" "Cancer-related genes, Congenital disorder of glycosylation, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 96306653.7" "Tissue enhanced" "Detected in many" "lymphoid tissue: 66877434.6" "CAB007781, HPA065158, HPA069341" Supported Supported Cytosol NA No 300000 "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 54 Cytosol "CAB007781: , HPA065158: , HPA069341: " "unprognostic (1.53e-1)" "unprognostic (2.23e-1)" "unprognostic (8.47e-3)" "unprognostic (3.03e-2)" "unprognostic (1.85e-2)" "unprognostic (2.53e-1)" "unprognostic (1.09e-1)" "unprognostic (3.80e-1)" "unprognostic (8.73e-2)" "unprognostic (3.91e-3)" "validated prognostic unfavorable (5.72e-9)" "validated prognostic unfavorable (3.48e-4)" "unprognostic (8.78e-2)" "validated prognostic unfavorable (1.51e-11)" "validated prognostic unfavorable (1.21e-4)" "unprognostic (6.04e-3)" "unprognostic (5.20e-3)" "unprognostic (3.38e-3)" "unprognostic (8.84e-2)" "unprognostic (7.33e-2)" "unprognostic (2.15e-3)" "unprognostic (2.64e-1)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (4.31e-1)" "unprognostic (2.14e-2)" "unprognostic (4.46e-1)" "unprognostic (2.53e-2)" "unprognostic (9.72e-2)" "unprognostic (1.32e-2)" "unprognostic (6.92e-2)" CALD1 "CDM, H-CAD, h-CD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 2360.2;Decidual stromal cells: 2069.1;Extravillous trophoblasts: 1516.8;Hepatic stellate cells: 4298.9;Leydig cells: 2586.7;Ovarian stromal cells: 1689.0;Pericytes: 2893.8;Peritubular myoid cells: 2468.1;Salivary myoepithelial cells: 1486.3;Smooth muscle cells: 4434.5;Vascular smooth muscle cells: 3489.9" "Cell type enhanced" "Detected in many" "Mural cells: 3489.9;Smooth muscle cells: 4434.5;Stellate cells: 4298.9" "Group enriched" "Detected in all" 5 "pericyte: 1943.5;vascular associated smooth muscle cell: 2377.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Smooth muscle cells: 1857316282.3" "Tissue enhanced" "Detected in all" "intestine: 1976809473.5" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 46000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 108 "Plasma membrane, Actin filaments" "CAB000006: , HPA008066: , HPA017330: " "unprognostic (3.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.72e-1)" "unprognostic (1.82e-2)" "unprognostic (2.38e-3)" "unprognostic (8.10e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (3.64e-4)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (2.70e-4)" "potential prognostic favorable (1.21e-6)" "unprognostic (3.57e-2)" "unprognostic (4.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.33e-1)" "unprognostic (4.32e-2)" "unprognostic (5.50e-2)" "unprognostic (1.58e-2)" "unprognostic (4.28e-2)" "unprognostic (2.44e-2)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (7.91e-2)" "unprognostic (2.62e-1)" "unprognostic (5.27e-2)" "unprognostic (3.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.50e-2)" "unprognostic (1.48e-3)" "unprognostic (1.33e-1)" "unprognostic (8.81e-2)" "unprognostic (5.10e-2)" CALML4 "MGC4809, NY-BR-20" ENSG00000129007 "Calmodulin like 4" Q96GE6 15 68190705-68206079 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 27.3;intestine: 36.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 6.6;Choroid plexus epithelial cells: 16.2;Colonocytes: 21.0;Endometrial ciliated cells: 13.5;Enteric transient amplifying cells: 8.9;Enterocytes: 18.0;Epididymal efferent duct absorptive cells: 11.5;Epididymal efferent duct ciliated cells: 15.1;Fallopian tube ciliated cells: 18.4;Kupffer cells: 11.3;Microglia: 9.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 18.4;Ductal cells: 11.5;Enterocytes: 21.0;Glial cells: 9.6;Mononuclear phagocytes: 11.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 33.5" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 4 "choroid plexus: 13.7" "Group enriched" "Detected in some" 40 "classical monocyte: 30.8;intermediate monocyte: 56.6;myeloid DC: 18.4;neutrophil: 18.1;non-classical monocyte: 66.4" "Group enriched" "Detected in many" 59 "dendritic cells: 18.4;granulocytes: 18.1;monocytes: 66.4" "Cancer enhanced" "Detected in all" "Myeloma: 61.4" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Glomeruli: 3038512.6;Hepatocytes: 2861552.3;Proximal tubules: 6164583.6" "Group enriched" "Detected in some" "intestine: 1642850.8;kidney: 4383186.4" HPA051109 Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA051109: " "unprognostic (1.13e-1)" "unprognostic (3.94e-2)" "unprognostic (4.38e-2)" "unprognostic (2.92e-1)" "unprognostic (3.11e-2)" "unprognostic (5.16e-2)" "unprognostic (3.84e-1)" "unprognostic (6.59e-3)" "unprognostic (7.17e-2)" "unprognostic (6.16e-2)" "potential prognostic favorable (5.96e-5)" "unprognostic (4.20e-2)" "unprognostic (4.44e-2)" "unprognostic (4.96e-2)" "unprognostic (2.05e-1)" "unprognostic (6.56e-2)" "unprognostic (1.77e-1)" "unprognostic (2.00e-2)" "unprognostic (1.07e-2)" "unprognostic (1.89e-1)" "unprognostic (1.28e-2)" "unprognostic (1.78e-2)" "unprognostic (3.20e-2)" "unprognostic (5.76e-3)" "unprognostic (1.26e-2)" "unprognostic (1.32e-2)" "unprognostic (2.66e-1)" "unprognostic (1.39e-3)" "unprognostic (2.00e-1)" "unprognostic (3.15e-1)" "unprognostic (1.29e-1)" CALN1 CABP8 ENSG00000183166 "Calneuron 1" Q9BXU9 7 71779491-72447151 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 52.6;lymphoid tissue: 23.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 353.0;Bergmann glia: 548.8;Brain excitatory neurons: 897.4;Brain inhibitory neurons: 453.1;Differentiating spermatogonia: 455.0;Hematopoietic stem cells: 1502.2;Other brain neurons: 259.2;Pituitary stem cells: 454.0;Retinal amacrine cells: 338.7;Thymocytes: 239.7;Undifferentiated spermatogonia: 644.1" "Cell type enhanced" "Detected in many" "Glial cells: 548.8;Neuronal cells: 897.4;Spermatogenic cell types: 644.1;Stem cells: 1502.2" "Cell type enhanced" "Detected in all" "upper rhombic lip: 1901.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 4.1;Leukemia: 2.4;Myeloma: 8.5;Neuroblastoma: 2.4" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036278, HPA036708" Approved Uncertain "Vesicles,Plasma membrane" No No "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 8 Vesicles "Plasma membrane" "HPA036278: , HPA036708: " "unprognostic (7.14e-2)" "unprognostic (5.64e-2)" "unprognostic (9.06e-2)" "unprognostic (1.37e-2)" "unprognostic (3.11e-2)" "unprognostic (1.05e-1)" CAMK1D CKLiK ENSG00000183049 "Calcium/calmodulin dependent protein kinase ID" Q8IU85 10 12349547-12835545 "Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response, Neurogenesis" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.2;retina: 53.6" "Group enriched" "Detected in all" 4 "Cone photoreceptor cells: 4045.0;Neutrophils: 6615.0;Rod photoreceptor cells: 2980.4" "Group enriched" "Detected in all" 6 "Neuronal cells: 4045.0;Neutrophils: 6615.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 64.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 64.4" "Low cancer specificity" "Detected in many" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 19678958.7;Microglia and Neuropil: 19816515.0" "Tissue enriched" "Detected in many" "cerebral cortex: 40864898.4" HPA007266 Approved Approved "Nucleoplasm,Basal body,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 "Nucleoplasm, Cytosol" "Basal body" "HPA007266: " "unprognostic (2.10e-3)" "unprognostic (5.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.88e-1)" "unprognostic (1.15e-1)" "unprognostic (4.98e-1)" "potential prognostic favorable (2.86e-4)" "unprognostic (3.63e-2)" "unprognostic (2.48e-3)" "potential prognostic favorable (3.94e-4)" "unprognostic (6.16e-3)" "unprognostic (1.62e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (4.96e-4)" "potential prognostic favorable (8.61e-6)" "unprognostic (2.43e-1)" "unprognostic (2.88e-1)" "potential prognostic favorable (3.46e-4)" "unprognostic (1.31e-2)" "unprognostic (3.17e-1)" "unprognostic (1.27e-1)" "unprognostic (3.97e-2)" "unprognostic (2.23e-1)" "unprognostic (4.44e-2)" "unprognostic (4.68e-2)" "unprognostic (3.96e-2)" "unprognostic (4.18e-2)" "unprognostic (1.93e-1)" "unprognostic (2.21e-2)" "unprognostic (6.28e-2)" CAMK1G "CLICKIII, dJ272L16.1, VWS1" ENSG00000008118 "Calcium/calmodulin dependent protein kinase IG" Q96NX5 1 209583714-209613939 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Allosteric enzyme, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 48.1;ovary: 25.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.6;Brain inhibitory neurons: 22.9;Endometrial glandular cells: 13.0;Endometrial luminal cells: 20.4;Endometrial secretory cells: 25.3;Epididymal basal cells: 14.2;Epididymal principal cells: 8.6;Other brain neurons: 14.4;Ovarian stromal cells: 12.6;Retinal ganglion cells: 7.7;Salivary basal cells: 39.1;Salivary myoepithelial cells: 7.8;Somatotrophs: 13.6" "Cell type enhanced" "Detected in many" "Basal cells: 39.1;Luminal cells: 20.4;Neuronal cells: 22.9;Secretory cells: 25.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 8.2;Sarcoma: 2.3;thyroid cancer: 2.3" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1187 "Astrocytes and Neuropil: 70714.1;Microglia and Neuropil: 178058.9;Neurons: 107281.3" "Tissue enriched" "Detected in single" 69680 "cerebral cortex: 6967951.4" HPA077157 Approved "Nucleoplasm,Primary cilium,Basal body,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 "Nucleoplasm, Cytosol" "Primary cilium, Basal body" "HPA077157: " "unprognostic (1.26e-1)" "unprognostic (4.77e-2)" "unprognostic (1.56e-1)" "unprognostic (4.22e-2)" "unprognostic (5.13e-2)" "unprognostic (6.32e-2)" "unprognostic (4.39e-2)" "unprognostic (1.74e-2)" "unprognostic (4.76e-3)" "unprognostic (4.65e-2)" CAMK2N1 CaMKIINalpha ENSG00000162545 "Calcium/calmodulin dependent protein kinase II inhibitor 1" Q7Z7J9 1 20482391-20486210 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 582.0" "Cell type enhanced" "Detected in many" "Colonocytes: 495.7;Epididymal clear cells: 528.7;Epididymal efferent duct absorptive cells: 300.0;Esophageal apical cells: 360.7;Goblet cells: 465.2;Ocular epithelial cells: 298.1;Oligodendrocytes: 288.0;Salivary duct cells: 470.4" "Cell type enhanced" "Detected in many" "Ductal cells: 470.4;Enterocytes: 495.7;Goblet cells: 465.2;Reproductive supporting cells: 528.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6;MAIT T-cell: 1.1" "Lineage enhanced" "Detected in single" "T-cells: 1.6" "Low cancer specificity" "Detected in many" "Heart muscle - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 13992 "cerebral cortex: 1399168.0" "HPA074969, HPA075200" Approved Approved "Primary cilium,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Cytosol "Primary cilium" "HPA074969: , HPA075200: " "potential prognostic favorable (1.42e-4)" "unprognostic (1.22e-1)" "unprognostic (1.34e-2)" "unprognostic (2.34e-3)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (1.41e-2)" "unprognostic (6.79e-2)" "potential prognostic unfavorable (5.68e-7)" "unprognostic (3.25e-1)" "validated prognostic favorable (2.92e-7)" "validated prognostic favorable (9.58e-6)" "unprognostic (6.53e-2)" "validated prognostic unfavorable (1.19e-4)" "validated prognostic unfavorable (6.25e-5)" "unprognostic (1.02e-3)" "unprognostic (1.15e-1)" "unprognostic (5.35e-3)" "unprognostic (3.55e-3)" "unprognostic (8.33e-2)" "unprognostic (4.69e-2)" "unprognostic (1.53e-2)" "unprognostic (2.52e-2)" "unprognostic (9.41e-2)" "unprognostic (1.98e-2)" "unprognostic (1.91e-1)" "unprognostic (3.43e-1)" "unprognostic (6.13e-2)" "unprognostic (1.63e-1)" "unprognostic (1.55e-2)" "unprognostic (1.02e-1)" CAMKK1 "CAMKKA, DKFZp761M0423, MGC34095" ENSG00000004660 "Calcium/calmodulin dependent protein kinase kinase 1" Q8N5S9 17 3860315-3894891 "Enzymes, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 64.6;Lactotrophs: 63.2;Neutrophils: 56.5;Retinal bipolar cells: 80.9;Retinal ganglion cells: 73.4;Sertoli cells: 91.0;Somatotrophs: 99.4" "Cell type enhanced" "Detected in many" "Neuronal cells: 80.9;Pituitary endocrine cells: 99.4;Reproductive supporting cells: 91.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 24367441.4;Microglia and Neuropil: 36337308.2;Neurons: 23248697.3" "Tissue enriched" "Detected in some" "cerebral cortex: 466755694.7" "CAB009111, HPA028062" Approved Approved Cytosol No No "Cluster 7: Non-specific - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 Cytosol "CAB009111: , HPA028062: " "unprognostic (1.33e-1)" "unprognostic (3.46e-3)" "unprognostic (6.88e-2)" "unprognostic (4.69e-1)" "unprognostic (9.12e-2)" "unprognostic (1.28e-2)" "unprognostic (3.25e-2)" "unprognostic (1.45e-1)" "unprognostic (6.64e-2)" "unprognostic (1.42e-1)" "unprognostic (6.31e-2)" "unprognostic (7.65e-2)" "unprognostic (1.34e-2)" "unprognostic (2.73e-3)" "potential prognostic favorable (5.83e-4)" "unprognostic (1.53e-1)" "unprognostic (2.18e-1)" "unprognostic (1.20e-1)" "unprognostic (4.43e-2)" "unprognostic (3.73e-2)" "potential prognostic favorable (2.26e-4)" "unprognostic (5.21e-2)" "unprognostic (7.40e-2)" "unprognostic (9.22e-3)" "unprognostic (1.07e-2)" "unprognostic (1.65e-1)" "unprognostic (9.18e-2)" "unprognostic (1.49e-1)" "unprognostic (1.36e-1)" "unprognostic (8.03e-2)" CAMKV "MGC8407, VACAMKL" ENSG00000164076 "CaM kinase like vesicle associated" Q8NCB2 3 49857988-49869935 "Enzymes, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "brain: 220.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 45.8;Brain inhibitory neurons: 84.9;Early spermatids: 7.4;Late spermatids: 15.4;Oligodendrocytes: 7.7;Other brain neurons: 36.4;Retinal amacrine cells: 42.1" "Cell type enriched" "Detected in some" 5 "Neuronal cells: 84.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 7.4;Testicular Germ Cell Tumor (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 23.5" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 820645 "Astrocytes and Neuropil: 74401044.0;Microglia and Neuropil: 108055718.2;Neurons: 63736831.3" "Tissue enriched" "Detected in single" 719117 "cerebral cortex: 71911658.1" "HPA007656, CAB034931" Enhanced Supported Approved "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 43 Nucleoplasm "Cytokinetic bridge" "CAB034931: , HPA007656: " "unprognostic (3.31e-1)" "potential prognostic favorable (9.55e-5)" "unprognostic (9.60e-2)" CAMSAP1 "DKFZp434F195, FLJ31228" ENSG00000130559 "Calmodulin regulated spectrin associated protein 1" Q5T5Y3 9 135808487-135907546 "Predicted intracellular proteins" "Disease variant, Intellectual disability, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 97.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 370.6;Epididymal basal cells: 183.9;Ocular epithelial cells: 230.7;Rod photoreceptor cells: 493.6" "Cell type enhanced" "Detected in all" "Neuronal cells: 493.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 4228971.6" "Tissue enhanced" "Detected in many" "cerebral cortex: 2157162.4" "HPA020527, HPA024161" Approved Supported "Mitotic spindle,Cytosol" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "Mitotic spindle, Cytosol" "HPA020527: , HPA024161: " "unprognostic (2.01e-1)" "unprognostic (1.92e-3)" "unprognostic (2.14e-2)" "unprognostic (1.63e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (3.95e-1)" "potential prognostic favorable (3.22e-4)" "unprognostic (4.17e-2)" "unprognostic (2.85e-2)" "potential prognostic favorable (5.10e-7)" "unprognostic (2.83e-3)" "unprognostic (1.06e-1)" "unprognostic (3.30e-3)" "unprognostic (1.82e-1)" "unprognostic (3.03e-1)" "unprognostic (5.65e-3)" "unprognostic (2.28e-1)" "unprognostic (8.46e-3)" "unprognostic (9.44e-2)" "unprognostic (4.82e-2)" "unprognostic (6.23e-2)" "unprognostic (5.18e-3)" "unprognostic (8.13e-2)" "unprognostic (3.17e-2)" "unprognostic (3.04e-3)" "unprognostic (3.12e-1)" "unprognostic (1.39e-1)" "unprognostic (5.75e-1)" "unprognostic (1.30e-2)" "unprognostic (2.11e-1)" CAMTA1 KIAA0833 ENSG00000171735 "Calmodulin binding transcription activator 1" Q9Y6Y1 1 6785454-7769706 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocytes: 1075.6;Retinal ganglion cells: 1035.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 35578 "Neurons: 3557824.0" "Tissue enriched" "Detected in single" 1136 "cerebral cortex: 113608.7" "HPA036342, HPA036343" Approved Approved "Nucleoli,Basal body,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 109: Neurons - Neuronal signaling" Cytosol "Nucleoli, Basal body" "HPA036342: , HPA036343: " "unprognostic (1.71e-1)" "unprognostic (1.51e-1)" "unprognostic (1.00e-1)" "unprognostic (2.60e-2)" "unprognostic (5.97e-2)" "unprognostic (1.20e-1)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.10e-4)" "unprognostic (4.97e-2)" "unprognostic (1.90e-1)" "unprognostic (1.83e-3)" "unprognostic (3.97e-2)" "unprognostic (7.22e-3)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (2.87e-3)" "unprognostic (3.68e-3)" "unprognostic (3.95e-1)" "unprognostic (1.74e-1)" "unprognostic (3.79e-2)" "unprognostic (2.55e-2)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (4.16e-2)" "unprognostic (1.35e-1)" "unprognostic (2.00e-1)" "unprognostic (1.92e-1)" "unprognostic (1.79e-1)" "unprognostic (3.32e-1)" "unprognostic (1.36e-1)" "unprognostic (3.37e-1)" "unprognostic (4.59e-2)" CAMTA2 KIAA0909 ENSG00000108509 "Calmodulin binding transcription activator 2" O94983 17 4967992-4987675 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 84.7" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 84.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14872 "Neurons: 1487201.7" "Tissue enriched" "Detected in single" 144 "cerebral cortex: 14435.5" "HPA027835, HPA051147" Supported "Nucleoplasm,Vesicles,Actin filaments,Mitochondria,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Nucleoplasm "Vesicles, Actin filaments, Mitochondria, Cytosol" "HPA027835: , HPA051147: " "unprognostic (9.47e-2)" "unprognostic (1.14e-1)" "unprognostic (1.22e-1)" "unprognostic (2.90e-2)" "unprognostic (2.23e-1)" "unprognostic (6.86e-2)" "unprognostic (1.22e-1)" "unprognostic (3.05e-1)" "unprognostic (7.70e-2)" "unprognostic (1.51e-2)" "validated prognostic favorable (1.10e-5)" "validated prognostic favorable (6.45e-5)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.11e-1)" "unprognostic (4.98e-3)" "unprognostic (4.11e-2)" "unprognostic (5.45e-2)" "unprognostic (2.19e-2)" "unprognostic (2.73e-1)" "unprognostic (9.24e-2)" "unprognostic (8.08e-3)" "potential prognostic favorable (3.11e-4)" "unprognostic (1.61e-2)" "unprognostic (2.40e-1)" "unprognostic (7.01e-2)" "unprognostic (1.47e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.41e-1)" "unprognostic (3.01e-2)" "unprognostic (3.98e-1)" CAND1 "DKFZp434M1414, KIAA0829, TIP120, TIP120A" ENSG00000111530 "Cullin associated and neddylation dissociated 1" Q86VP6 12 67269358-67319953 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Skin - Mitotic cells (Skin)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA055748, HPA062833, HPA069053" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No 5200000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 98 "Golgi apparatus, Cytosol" Nucleoplasm "HPA055748: , HPA062833: , HPA069053: " "unprognostic (1.15e-1)" "unprognostic (1.83e-2)" "unprognostic (3.31e-2)" "unprognostic (5.34e-2)" "unprognostic (6.46e-3)" "unprognostic (2.58e-1)" "unprognostic (3.32e-1)" "unprognostic (4.87e-3)" "unprognostic (1.74e-1)" "unprognostic (3.36e-3)" "potential prognostic favorable (5.34e-7)" "unprognostic (3.41e-2)" "unprognostic (1.90e-2)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (5.54e-6)" "unprognostic (1.80e-2)" "unprognostic (3.65e-2)" "unprognostic (4.18e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (2.45e-3)" "unprognostic (1.24e-1)" "unprognostic (6.10e-2)" "unprognostic (3.30e-2)" "unprognostic (2.74e-2)" "unprognostic (1.01e-1)" "unprognostic (2.11e-1)" "unprognostic (3.80e-1)" "unprognostic (2.25e-1)" "unprognostic (1.34e-1)" CAP1 CAP ENSG00000131236 "Cyclase associated actin cytoskeleton regulatory protein 1" Q01518 1 40040233-40072649 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 697.3;Late spermatids: 650.1;Megakaryocytes: 933.4;Neutrophil progenitors: 1261.9;Neutrophils: 1953.7;Platelets: 1016.9" "Cell type enhanced" "Detected in all" "Neutrophils: 1953.7;Platelets: 1016.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA030124 Approved Approved Cytosol NA NA 77000000 "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 26 Cytosol "HPA030124: " "unprognostic (2.97e-1)" "unprognostic (1.65e-1)" "unprognostic (3.83e-3)" "potential prognostic unfavorable (5.53e-5)" "unprognostic (2.81e-3)" "unprognostic (4.64e-1)" "unprognostic (1.06e-1)" "unprognostic (5.66e-1)" "unprognostic (5.03e-2)" "unprognostic (1.53e-3)" "potential prognostic favorable (3.69e-8)" "unprognostic (1.55e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (1.51e-7)" "unprognostic (2.16e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (2.94e-5)" "unprognostic (3.14e-2)" "unprognostic (9.86e-3)" "unprognostic (8.27e-3)" "unprognostic (1.57e-1)" "unprognostic (3.34e-2)" "unprognostic (5.80e-2)" "unprognostic (4.67e-1)" "unprognostic (2.43e-1)" "unprognostic (6.27e-2)" "unprognostic (4.05e-1)" "unprognostic (1.65e-1)" "unprognostic (3.78e-2)" CAPG "AFCP, MCP" ENSG00000042493 "Capping actin protein, gelsolin like" P40121 2 85394753-85418432 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 718.6;Esophageal basal cells: 355.0;Esophageal suprabasal cells: 617.5;Extravillous trophoblasts: 508.5;Hofbauer cells: 508.0;Mast cells: 521.0;Urothelial cells: 332.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 718.6;Mast cells: 521.0;Mononuclear phagocytes: 508.0;Suprabasal cells: 617.5;Trophoblast cells: 508.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 47.4;leukocyte: 19.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 1142.1;classical monocyte: 1141.1;eosinophil: 714.5;intermediate monocyte: 431.9;memory B-cell: 577.9;myeloid DC: 1364.5;naive B-cell: 520.3;NK-cell: 606.9;plasmacytoid DC: 961.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Lung - Macrophages, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA018843, HPA019080, HPA019092" Enhanced Supported "Nucleoplasm,Mitotic chromosome" Yes No 3400000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Nucleoplasm "Mitotic chromosome" "HPA018843: , HPA019080: , HPA019092: " "unprognostic (2.32e-1)" "unprognostic (1.72e-1)" "unprognostic (1.28e-1)" "unprognostic (2.12e-1)" "unprognostic (1.15e-1)" "unprognostic (1.85e-2)" "unprognostic (1.18e-2)" "unprognostic (1.49e-2)" "unprognostic (7.79e-2)" "unprognostic (2.98e-3)" "unprognostic (6.77e-2)" "unprognostic (1.11e-2)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (4.65e-5)" "unprognostic (4.60e-1)" "unprognostic (8.93e-2)" "unprognostic (4.04e-2)" "unprognostic (1.33e-1)" "unprognostic (1.20e-2)" "unprognostic (8.03e-2)" "unprognostic (1.58e-1)" "unprognostic (3.68e-3)" "unprognostic (2.21e-2)" "unprognostic (1.71e-1)" "unprognostic (5.20e-2)" "unprognostic (3.74e-1)" "unprognostic (4.02e-2)" "unprognostic (1.11e-1)" "unprognostic (5.05e-2)" "unprognostic (1.07e-2)" "unprognostic (2.65e-2)" CAPN11 ENSG00000137225 "Calpain 11" Q9UMQ6 6 44158811-44184401 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 28.4" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 31.0;Early primary spermatocytes: 10.7;Early spermatids: 21.6;Late primary spermatocytes: 117.4;Late spermatids: 11.3;Platelets: 9.8" "Group enriched" "Detected in many" 7 "Secretory gland support: 31.0;Spermatogenic cell types: 117.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Leukemia: 1.0;Rhabdoid: 4.0" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB018070, HPA030955" Enhanced Approved "Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Mid piece, Principal piece, End piece" "Acrosome, Equatorial segment" "CAB018070: , HPA030955: " "unprognostic (2.80e-1)" CAPN2 "CANPL2, CANPml, mCANP" ENSG00000162909 "Calpain 2" P17655 1 223701593-223776018 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 677.4;Esophageal apical cells: 740.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 740.8" "Cell type enhanced" "Detected in all" "astrocyte: 177.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Large ducts: 121539575.9" "Low tissue specificity" "Detected in all" HPA024470 Approved Approved Supported "Cytosol,Connecting piece,Mid piece,Principal piece" NA NA 2500000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 22 "Cytosol, Connecting piece, Mid piece" "Principal piece" "HPA024470: " "unprognostic (1.38e-1)" "unprognostic (2.67e-3)" "unprognostic (2.64e-2)" "unprognostic (1.73e-3)" "unprognostic (1.63e-1)" "unprognostic (6.13e-2)" "unprognostic (1.44e-1)" "unprognostic (4.16e-1)" "unprognostic (4.76e-2)" "unprognostic (3.20e-1)" "potential prognostic favorable (4.24e-6)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (4.07e-2)" "unprognostic (7.63e-2)" "unprognostic (5.51e-2)" "unprognostic (7.82e-3)" "unprognostic (3.16e-3)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (2.03e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (6.98e-4)" "unprognostic (5.95e-2)" "unprognostic (7.39e-2)" "unprognostic (3.44e-1)" "unprognostic (3.48e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (1.92e-1)" "unprognostic (2.11e-1)" "unprognostic (6.34e-2)" CAPN7 PalBH ENSG00000131375 "Calpain 7" Q9Y6W3 3 15206152-15252916 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA004745, HPA046617" Uncertain Approved Centrosome,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 55: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 79: Photoreceptor cells - Phototransduction" 12 Cytosol Centrosome "HPA004745: , HPA046617: " "unprognostic (2.16e-1)" "unprognostic (4.76e-2)" "unprognostic (6.85e-2)" "unprognostic (1.68e-1)" "potential prognostic favorable (3.97e-4)" "unprognostic (3.03e-1)" "unprognostic (1.29e-1)" "unprognostic (3.31e-2)" "unprognostic (3.90e-3)" "unprognostic (9.36e-2)" "potential prognostic favorable (7.12e-7)" "unprognostic (1.57e-3)" "unprognostic (1.11e-1)" "unprognostic (4.26e-2)" "unprognostic (1.57e-1)" "unprognostic (3.65e-1)" "unprognostic (2.35e-1)" "unprognostic (5.16e-2)" "unprognostic (3.32e-2)" "unprognostic (8.05e-2)" "unprognostic (1.48e-2)" "unprognostic (2.29e-1)" "unprognostic (1.71e-2)" "unprognostic (7.27e-2)" "unprognostic (1.10e-2)" "unprognostic (1.20e-3)" "unprognostic (2.19e-1)" "unprognostic (1.73e-1)" "unprognostic (1.99e-1)" "unprognostic (4.93e-2)" "unprognostic (1.48e-1)" CAPN8 nCL-2 ENSG00000203697 "Calpain 8" A6NHC0 1 223538007-223665723 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "stomach 1: 274.8" "Cell type enriched" "Detected in many" 5 "Foveolar cells: 1721.3" "Cell type enriched" "Detected in many" 5 "Gastric glandular cells: 1721.3" "Cell type enhanced" "Detected in many" "amygdala excitatory: 7.9;ependymal cell: 6.6" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 47.5;Pancreatic Adenocarcinoma (TCGA): 64.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 30.1;colorectal cancer: 26.4;Gastric cancer: 30.1" "Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA073939 Approved "Nucleoplasm,Nuclear membrane,Vesicles" No NA "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" "Nucleoplasm, Nuclear membrane, Vesicles" "HPA073939: " "unprognostic (9.41e-2)" "unprognostic (4.38e-2)" "unprognostic (1.19e-1)" "unprognostic (1.76e-2)" "unprognostic (2.15e-1)" "unprognostic (2.30e-1)" "unprognostic (2.23e-2)" "unprognostic (3.47e-1)" "unprognostic (1.51e-1)" "unprognostic (1.16e-1)" "unprognostic (3.00e-3)" "unprognostic (4.68e-1)" "unprognostic (7.28e-3)" "unprognostic (1.27e-1)" "unprognostic (1.24e-2)" "unprognostic (3.22e-2)" "unprognostic (3.03e-2)" "unprognostic (1.03e-1)" "unprognostic (1.32e-1)" "unprognostic (2.38e-1)" CAPNS2 "MGC12536, MGC14804" ENSG00000256812 "Calpain small subunit 2" Q96L46 16 55566684-55567687 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 82.6;skin 1: 99.0;vagina: 33.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 29.3;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 32.9;Head and Neck Squamous Cell Carcinoma (TCGA): 40.7;Lung Squamous Cell Carcinoma (TCGA): 30.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 3.8;intermediate monocyte: 1.0" "Group enriched" "Detected in many" 9 "granulocytes: 3.8;monocytes: 1.0" "Group enriched" "Detected in some" 5 "Bladder cancer: 6.3;Esophageal cancer: 18.9;Gallbladder cancer: 6.2;Gastric cancer: 4.9;head and neck cancer: 15.3" "Prostate - Urothelial cells" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 417442 "Keratinocytes: 41744239.2" "Group enriched" "Detected in many" "intestine: 2779779.4;lymphoid tissue: 6656699.0;skin: 9478370.6" "HPA059749, HPA076768" Enhanced Approved Cytosol NA NA 66000 "Cluster 19: Eosinophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" 18 Cytosol "HPA059749: , HPA076768: " "unprognostic (9.07e-2)" "unprognostic (2.68e-1)" "unprognostic (5.12e-3)" "unprognostic (5.02e-2)" "unprognostic (9.61e-2)" "unprognostic (5.19e-2)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.32e-1)" "unprognostic (1.86e-1)" "unprognostic (4.11e-2)" CAPRIN1 "caprin-1, GPIAP1, M11S1, RNG105" ENSG00000135387 "Cell cycle associated protein 1" Q14444 11 34051731-34102610 "Predicted intracellular proteins" Differentiation "Protein synthesis inhibitor, RNA-binding" "Autism, Autism spectrum disorder, Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 504.5;Late primary spermatocytes: 511.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 511.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA018126, HPA063617" Approved Supported "Centriolar satellite,Centrosome,Cytosol" NA NA 170000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 203 Cytosol "Centriolar satellite, Centrosome" "HPA018126: , HPA063617: " "unprognostic (4.86e-2)" "unprognostic (8.10e-2)" "unprognostic (5.30e-2)" "unprognostic (1.69e-2)" "unprognostic (1.71e-1)" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "unprognostic (3.75e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.70e-5)" "potential prognostic favorable (1.20e-7)" "unprognostic (3.38e-3)" "unprognostic (2.79e-1)" "unprognostic (8.14e-2)" "unprognostic (5.56e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (3.28e-2)" "unprognostic (1.43e-1)" "unprognostic (6.66e-2)" "unprognostic (5.41e-3)" "unprognostic (1.95e-3)" "unprognostic (2.87e-1)" "unprognostic (1.58e-1)" "unprognostic (1.91e-3)" "unprognostic (8.27e-2)" "unprognostic (3.52e-2)" "unprognostic (1.04e-1)" "unprognostic (1.26e-1)" "unprognostic (5.64e-2)" "unprognostic (1.33e-1)" CAPS "CAPS1, MGC126562" ENSG00000105519 Calcyphosine Q13938 19 5912339-5916211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 314.9" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 2807.6;Epididymal efferent duct ciliated cells: 3324.5;Fallopian tube ciliated cells: 4685.1;Respiratory ciliated cells: 3276.4" "Cell type enriched" "Detected in many" 9 "Ciliated cells: 4685.1" "Cell type enriched" "Detected in all" 23 "ependymal cell: 990.8" "Cancer enriched" "Detected in all" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 685.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "breast cancer: 76.6" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 716156286.4" "Tissue enriched" "Detected in all" "fallopian tube: 1083733842.6" HPA043520 Enhanced Supported "Plasma membrane,Cytosol" NA NA 27000 "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 Cytosol "Plasma membrane" "HPA043520: " "unprognostic (7.18e-3)" "unprognostic (2.13e-1)" "unprognostic (3.36e-1)" "unprognostic (1.30e-1)" "unprognostic (2.91e-2)" "unprognostic (2.52e-1)" "unprognostic (9.61e-2)" "unprognostic (4.38e-2)" "unprognostic (3.52e-3)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (1.41e-6)" "unprognostic (2.66e-2)" "unprognostic (3.92e-2)" "unprognostic (1.31e-1)" "unprognostic (1.57e-2)" "unprognostic (1.05e-3)" "unprognostic (9.57e-2)" "unprognostic (1.50e-1)" "unprognostic (3.32e-1)" "unprognostic (1.85e-1)" "unprognostic (1.90e-1)" "unprognostic (1.89e-1)" "unprognostic (3.28e-2)" "unprognostic (1.38e-1)" "unprognostic (7.09e-2)" "unprognostic (6.13e-3)" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (3.54e-2)" CAPS2 ENSG00000180881 "Calcyphosine 2" Q9BXY5 12 75275979-75390928 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 9.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 257.0;Ependymal cells: 351.0;Gonadotrophs: 250.8;Lactotrophs: 264.8;Respiratory ciliated cells: 207.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 351.0;Pituitary endocrine cells: 264.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 1167226.4" "Tissue enriched" "Detected in single" 31291 "fallopian tube: 3129104.7" "HPA039542, HPA040004" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles,Centrosome Yes No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" Nucleoli "Nucleoplasm, Vesicles, Centrosome" "HPA039542: , HPA040004: " "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.63e-2)" "unprognostic (4.87e-2)" "unprognostic (2.40e-2)" "unprognostic (1.70e-2)" "unprognostic (7.26e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-2)" "unprognostic (2.15e-1)" "unprognostic (4.45e-2)" CAPSL MGC26610 ENSG00000152611 "Calcyphosine like" Q8WWF8 5 35904288-35938779 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 86.0;fallopian tube: 104.2" "Cell type enhanced" "Detected in some" "Early spermatids: 149.7;Endometrial ciliated cells: 409.4;Ependymal cells: 148.5;Epididymal efferent duct ciliated cells: 536.4;Fallopian tube ciliated cells: 852.2;Late primary spermatocytes: 121.1;Late spermatids: 207.7;Respiratory ciliated cells: 771.5" "Cell type enriched" "Detected in many" 4 "Ciliated cells: 852.2" "Group enriched" "Detected in some" 9 "choroid plexus epithelial cell: 60.5;ependymal cell: 199.3" "Cancer enriched" "Detected in many" 5 "Uterine Corpus Endometrial Carcinoma (TCGA): 27.9" "Region enhanced" "Detected in all" "choroid plexus: 52.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 2.9;Leukemia: 2.2" "Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 91904 "Fallopian tube cells: 9190392.9" "Tissue enriched" "Detected in single" 125262 "fallopian tube: 12526232.7" "HPA046811, HPA058495" Enhanced Approved "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium" Yes No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 35: RS4;11 - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Nucleoplasm, Microtubules, Primary cilium" "Plasma membrane, Cytokinetic bridge" "HPA046811: , HPA058495: " "unprognostic (4.75e-2)" "unprognostic (2.34e-2)" "unprognostic (1.03e-1)" "unprognostic (2.81e-2)" "unprognostic (3.40e-3)" "unprognostic (1.94e-1)" "unprognostic (6.44e-2)" "unprognostic (3.66e-1)" "unprognostic (3.20e-1)" "unprognostic (5.03e-2)" "unprognostic (2.36e-2)" "unprognostic (8.26e-2)" "unprognostic (5.49e-3)" "unprognostic (1.72e-1)" "unprognostic (9.69e-3)" "unprognostic (2.27e-1)" CAPZB ENSG00000077549 "Capping actin protein of muscle Z-line subunit beta" P47756 1 19338775-19485539 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1378.0;Esophageal apical cells: 1195.9;Hofbauer cells: 1600.0;Late spermatids: 6076.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 6076.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 696.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA031531 Approved Approved Nucleoplasm,Vesicles,Cytosol No No 8500000 "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 905 "Nucleoplasm, Cytosol" Vesicles "HPA031531: " "unprognostic (7.13e-2)" "unprognostic (3.37e-1)" "unprognostic (2.42e-2)" "unprognostic (6.29e-2)" "unprognostic (1.97e-1)" "unprognostic (6.07e-2)" "unprognostic (1.00e-2)" "unprognostic (1.86e-2)" "unprognostic (1.08e-1)" "unprognostic (2.15e-2)" "unprognostic (3.68e-3)" "unprognostic (5.48e-2)" "unprognostic (6.65e-3)" "validated prognostic unfavorable (4.39e-5)" "validated prognostic unfavorable (6.46e-5)" "validated prognostic unfavorable (8.03e-4)" "validated prognostic unfavorable (4.17e-4)" "unprognostic (4.26e-2)" "unprognostic (1.66e-2)" "unprognostic (1.17e-2)" "unprognostic (2.03e-1)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (3.07e-1)" "unprognostic (1.12e-2)" "unprognostic (3.64e-2)" "unprognostic (1.34e-1)" "unprognostic (1.19e-1)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (8.85e-2)" CARF "ALS2CR8, FLJ21579, NYD-SP24" ENSG00000138380 "Calcium responsive transcription factor" Q8N187 2 202912214-202988263 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 109.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034557, HPA043191" Approved Approved "Nucleoli fibrillar center,Vesicles,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 5 Vesicles "Nucleoli fibrillar center, Cytosol" "HPA034557: , HPA043191: " "unprognostic (9.71e-2)" "unprognostic (3.64e-1)" "unprognostic (5.52e-3)" "unprognostic (5.66e-2)" "unprognostic (2.71e-2)" "unprognostic (1.73e-1)" "unprognostic (1.28e-1)" "unprognostic (2.83e-3)" "unprognostic (4.02e-1)" "unprognostic (4.10e-3)" "unprognostic (1.44e-3)" "potential prognostic favorable (9.77e-4)" "unprognostic (1.77e-1)" "unprognostic (3.10e-2)" "unprognostic (8.50e-2)" "unprognostic (5.48e-2)" "unprognostic (7.64e-2)" "unprognostic (2.99e-1)" "unprognostic (8.36e-2)" "unprognostic (8.66e-2)" "unprognostic (5.40e-3)" "unprognostic (2.03e-1)" "unprognostic (1.24e-2)" "unprognostic (2.02e-2)" "unprognostic (6.29e-2)" "unprognostic (2.25e-1)" "unprognostic (1.37e-1)" "unprognostic (3.36e-2)" "unprognostic (3.53e-1)" CARS1 CARS ENSG00000110619 "Cysteinyl-tRNA synthetase 1" P49589 11 3000922-3057613 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 91.6;Late primary spermatocytes: 101.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 101.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 75917903.9" "Low tissue specificity" "Detected in all" "HPA002383, HPA002384, CAB075734, CAB075735, CAB075736, CAB075737" Enhanced Enhanced Cytosol NA NA 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 102: Non-specific - Mixed function" 4 Cytosol "CAB075734: , CAB075735: , CAB075736: , CAB075737: , HPA002383: , HPA002384: " "unprognostic (2.78e-1)" "unprognostic (2.65e-2)" "unprognostic (9.26e-2)" "unprognostic (3.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.16e-3)" "unprognostic (4.88e-3)" "unprognostic (4.56e-2)" "potential prognostic unfavorable (9.81e-4)" "unprognostic (1.58e-1)" "unprognostic (1.62e-2)" "unprognostic (3.52e-2)" "unprognostic (5.10e-3)" "unprognostic (3.84e-3)" "unprognostic (1.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.26e-1)" "unprognostic (7.04e-2)" "unprognostic (1.03e-1)" "unprognostic (1.22e-2)" "unprognostic (2.31e-2)" "unprognostic (1.20e-1)" "unprognostic (8.11e-2)" "unprognostic (2.78e-1)" "unprognostic (6.48e-2)" "unprognostic (1.29e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (5.43e-5)" "unprognostic (1.94e-1)" CARS2 FLJ12118 ENSG00000134905 "Cysteinyl-tRNA synthetase 2, mitochondrial" Q9HA77 13 110641412-110713603 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 440.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 440.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA041776 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 "Nucleoplasm, Mitochondria" "HPA041776: " "unprognostic (4.13e-2)" "unprognostic (1.04e-1)" "unprognostic (2.46e-1)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.50e-1)" "unprognostic (9.70e-2)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (8.65e-2)" "potential prognostic favorable (3.39e-6)" "unprognostic (1.76e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" "unprognostic (6.65e-3)" "unprognostic (9.47e-2)" "unprognostic (2.08e-1)" "unprognostic (2.77e-1)" "unprognostic (1.90e-1)" "unprognostic (5.42e-2)" "unprognostic (1.33e-1)" "unprognostic (5.98e-2)" "unprognostic (3.74e-3)" "unprognostic (1.48e-1)" "unprognostic (7.24e-2)" "unprognostic (3.58e-2)" "unprognostic (1.30e-1)" "unprognostic (2.36e-1)" "unprognostic (4.83e-2)" CASD1 "C7orf12, FLJ21213, FLJ21879" ENSG00000127995 "CAS1 domain containing 1" Q96PB1 7 94509219-94557019 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 252.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 6700895.4" "Tissue enriched" "Detected in single" 79845 "salivary gland: 7984545.4" "HPA044404, HPA052908" Approved Approved Nucleoplasm Yes No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "HPA044404: , HPA052908: " "unprognostic (1.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.58e-1)" "unprognostic (2.72e-2)" "unprognostic (2.10e-1)" "unprognostic (2.63e-1)" "unprognostic (1.34e-1)" "unprognostic (2.28e-3)" "unprognostic (3.12e-1)" "unprognostic (2.69e-3)" "potential prognostic favorable (1.66e-5)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (6.89e-2)" "unprognostic (7.55e-3)" "unprognostic (3.75e-2)" "unprognostic (5.40e-2)" "unprognostic (3.06e-1)" "unprognostic (2.47e-1)" "unprognostic (3.83e-2)" "unprognostic (2.13e-2)" "unprognostic (6.99e-2)" "unprognostic (2.24e-2)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (2.61e-2)" "unprognostic (6.26e-2)" "unprognostic (1.56e-2)" "unprognostic (2.16e-1)" "unprognostic (1.22e-1)" "unprognostic (8.15e-2)" CASKIN1 "ANKS5A, KIAA1306" ENSG00000167971 "CASK interacting protein 1" Q8WXD9 16 2177180-2196605 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "brain: 57.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Astrocytes: 68.7;Bergmann glia: 46.2;Brain excitatory neurons: 34.1;Brain inhibitory neurons: 44.7;Epicardial cells: 34.1;Müller glia: 57.4;Oligodendrocyte progenitor cells: 43.7;Other brain neurons: 35.2;Retinal amacrine cells: 58.5;Retinal bipolar cells: 27.5;Retinal ganglion cells: 65.7;Retinal horizontal cells: 52.1" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 34.1;Glial cells: 68.7;Neuronal cells: 65.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 3.7;Prostate Adenocarcinoma (TCGA): 6.3;Uterine Corpus Endometrial Carcinoma (TCGA): 11.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.0" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 23474426.3;Microglia and Neuropil: 40415997.5;Neurons: 17250116.1" "Tissue enriched" "Detected in some" "cerebral cortex: 65586139.5" "HPA055990, HPA076882, CAB079050" Enhanced Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 2 Nucleoplasm "Nuclear bodies, Cytosol" "CAB079050: , HPA055990: , HPA076882: " "unprognostic (2.24e-1)" "unprognostic (2.00e-1)" "unprognostic (4.78e-2)" "unprognostic (1.53e-1)" "unprognostic (2.28e-1)" "unprognostic (5.11e-3)" "unprognostic (7.46e-2)" "unprognostic (3.09e-1)" "unprognostic (1.92e-1)" CASP7 "CMH-1, ICE-LAP3, MCH3" ENSG00000165806 "Caspase 7" P55210 10 113679162-113730907 "Cancer-related genes, Enzymes, Predicted intracellular proteins" Apoptosis "Allosteric enzyme, Hydrolase, Protease, RNA-binding, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 160.8;Enterocytes: 103.4;Foveolar cells: 134.8" "Cell type enhanced" "Detected in many" "Enterocytes: 160.8;Gastric glandular cells: 134.8" "Group enriched" "Detected in many" 6 "astrocyte: 25.6;Bergmann glia: 31.7;central nervous system macrophage: 13.1;choroid plexus epithelial cell: 15.4;endothelial cell: 25.6;ependymal cell: 25.0;fibroblast: 19.2;leukocyte: 28.8;pericyte: 19.5;vascular associated smooth muscle cell: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB025563, HPA069167" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" "Intracellular and membrane" Enzyme NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 31 "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane" "CAB025563: , HPA069167: " "unprognostic (1.45e-1)" "unprognostic (3.86e-3)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (6.86e-3)" "unprognostic (1.22e-1)" "unprognostic (3.47e-1)" "unprognostic (1.82e-2)" "unprognostic (2.77e-1)" "unprognostic (2.03e-2)" "potential prognostic favorable (3.20e-6)" "unprognostic (1.70e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (8.33e-4)" "unprognostic (1.29e-2)" "unprognostic (6.09e-2)" "unprognostic (3.59e-1)" "unprognostic (1.79e-1)" "unprognostic (1.22e-1)" "unprognostic (2.67e-1)" "unprognostic (4.43e-2)" "unprognostic (4.61e-2)" "unprognostic (3.47e-1)" "unprognostic (1.85e-2)" "unprognostic (1.65e-1)" "unprognostic (1.33e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-3)" "unprognostic (7.36e-2)" "unprognostic (2.24e-1)" "unprognostic (1.45e-1)" CASP8 "Casp-8, FLICE, MACH, MCH5" ENSG00000064012 "Caspase 8" Q14790 2 201233443-201361836 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Hydrolase, Protease, Thiol protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 381.6;Innate lymphoid cells: 190.3;Neutrophils: 238.4;NK-cells: 214.4;T-cells: 224.6;Thymocytes: 205.0" "Cell type enhanced" "Detected in many" "Myocytes: 381.6;Neutrophils: 238.4" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 49.1;leukocyte: 145.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "T-cells: 4769006.6" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2610447.4" "HPA001302, CAB002047, HPA005688" Approved Uncertain "Centriolar satellite,Mitochondria,Cytosol,Connecting piece,Mid piece,Principal piece" NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 83 "Mitochondria, Cytosol" "Centriolar satellite, Connecting piece, Mid piece, Principal piece" "CAB002047: , HPA001302: , HPA005688: " "potential prognostic favorable (5.84e-5)" "unprognostic (2.35e-1)" "unprognostic (7.58e-2)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (4.38e-2)" "unprognostic (3.82e-2)" "unprognostic (1.98e-1)" "unprognostic (4.35e-3)" "unprognostic (2.69e-2)" "unprognostic (5.33e-3)" "unprognostic (5.07e-2)" "unprognostic (2.88e-1)" "unprognostic (3.81e-2)" "unprognostic (1.72e-3)" "unprognostic (1.47e-1)" "unprognostic (3.44e-2)" "unprognostic (4.89e-3)" "unprognostic (3.88e-1)" "unprognostic (1.79e-1)" "unprognostic (1.26e-1)" "unprognostic (3.28e-1)" "unprognostic (4.43e-2)" "unprognostic (2.07e-2)" "unprognostic (2.71e-2)" "unprognostic (3.74e-2)" "unprognostic (2.13e-2)" "unprognostic (6.33e-3)" "unprognostic (1.04e-1)" "unprognostic (4.11e-1)" "unprognostic (4.44e-2)" "unprognostic (2.03e-1)" CASZ1 "castor, cst, FLJ20321, SRG, ZNF693" ENSG00000130940 "Castor zinc finger 1" Q86V15 1 10636604-10796650 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 46.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 892.2;Myonuclei: 333.0;Podocytes: 297.6;Prostatic glandular cells: 332.3;Rod photoreceptor cells: 1091.4" "Cell type enhanced" "Detected in many" "Neuronal cells: 1091.4" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 51.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Capillaries: 6446503.7;Cardiomyocytes: 5430523.3" "Tissue enriched" "Detected in single" 50 "intestine: 4999.4" "HPA028222, HPA029927" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 36: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 4 Nucleoplasm "Vesicles, Cytosol" "HPA028222: , HPA029927: " "unprognostic (9.95e-3)" "unprognostic (1.05e-1)" "unprognostic (2.96e-1)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" "unprognostic (4.89e-1)" "unprognostic (1.02e-1)" "unprognostic (4.60e-2)" "unprognostic (8.07e-2)" "unprognostic (1.68e-1)" "unprognostic (4.06e-2)" "unprognostic (1.22e-2)" "unprognostic (4.93e-2)" "potential prognostic unfavorable (1.47e-5)" "unprognostic (6.78e-2)" "potential prognostic favorable (8.08e-4)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (7.92e-2)" "unprognostic (4.05e-2)" "unprognostic (1.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.33e-1)" "unprognostic (1.85e-1)" "unprognostic (1.24e-1)" "unprognostic (3.14e-1)" "unprognostic (8.41e-2)" "unprognostic (7.53e-2)" "unprognostic (9.95e-2)" "unprognostic (8.81e-3)" "unprognostic (2.27e-1)" CATSPER1 CATSPER ENSG00000175294 "Cation channel sperm associated 1" Q8NEC5 11 66016752-66026479 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 16.5" "Cell type enhanced" "Detected in some" "Early spermatids: 42.9;Extravillous trophoblasts: 9.8;Late primary spermatocytes: 36.9;Mast cells: 47.1;Megakaryocytes: 12.4;monocytes: 18.2;NK-cells: 12.1;Platelets: 36.6" "Cell type enhanced" "Detected in some" "Mast cells: 47.1;Mononuclear phagocytes: 18.2;Platelets: 36.6;Spermatogenic cell types: 42.9" "Cell type enhanced" "Detected in some" "leukocyte: 1.1;vascular associated smooth muscle cell: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 16.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA044528 Supported "Principal piece" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 23: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 58: Mast cells - Allergic inflammatory responses" 97 "Principal piece" "HPA044528: " "unprognostic (3.46e-1)" "potential prognostic unfavorable (6.38e-5)" CATSPER2 ENSG00000166762 "Cation channel sperm associated 2" Q96P56 15 43628503-43668118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Differentiation, Ion transport, Spermatogenesis, Transport" "Calcium channel, Developmental protein, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 21.4;testis: 14.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 154.4;Cone photoreceptor cells: 196.7;Corticotrophs: 142.5;Rod photoreceptor cells: 306.3;Sertoli cells: 144.0" "Cell type enhanced" "Detected in many" "Neuronal cells: 306.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA042709 Uncertain "Vesicles,Plasma membrane,Primary cilium,Principal piece,End piece" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "End piece" "Vesicles, Plasma membrane, Primary cilium, Principal piece" "HPA042709: " "unprognostic (2.19e-2)" "unprognostic (4.12e-1)" "unprognostic (2.24e-2)" "unprognostic (2.48e-1)" "unprognostic (3.81e-2)" "unprognostic (2.28e-2)" "unprognostic (3.36e-2)" "unprognostic (2.20e-2)" "unprognostic (4.00e-2)" "unprognostic (3.28e-1)" "unprognostic (4.31e-2)" "unprognostic (3.56e-1)" "unprognostic (2.25e-2)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.24e-1)" "unprognostic (2.77e-1)" "unprognostic (3.08e-2)" "unprognostic (5.95e-3)" "unprognostic (3.89e-2)" "unprognostic (6.50e-3)" "unprognostic (5.75e-2)" "unprognostic (2.30e-3)" "unprognostic (5.09e-2)" "unprognostic (1.71e-1)" "unprognostic (1.05e-1)" "unprognostic (1.58e-2)" "unprognostic (2.30e-1)" CAV1 CAV ENSG00000105974 "Caveolin 1" Q03135 7 116524994-116561179 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Cancer-related genes, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1960.5;Basal keratinocytes: 1117.4;Breast myoepithelial cells: 641.5;Extravillous trophoblasts: 572.4;Hepatic stellate cells: 555.1;Lymphatic endothelial cells: 762.4;Melanocytes: 538.0;Pericytes: 555.3;Peritubular myoid cells: 495.1;Smooth muscle cells: 1110.3;Transitional alveolar cells: 880.9;Vascular endothelial cells: 942.6;Vascular smooth muscle cells: 827.9" "Cell type enhanced" "Detected in many" "Alveolar cells: 1960.5;Basal cells: 1117.4;Endothelial cells: 942.6;Smooth muscle cells: 1110.3" "Group enriched" "Detected in many" 12 "endothelial cell: 113.1;pericyte: 112.7;vascular associated smooth muscle cell: 329.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "basophil: 14.6;memory B-cell: 5.1" "Group enriched" "Detected in many" 57 "B-cells: 5.1;granulocytes: 14.6" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Alveolar cells type 1, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 169.0" "Group enriched" "Detected in many" "Alveolar cell types: 141958133.7;Capillaries: 147530289.6;Smooth muscle cells: 136765582.6" "Low tissue specificity" "Detected in all" "CAB003791, HPA049326, HPA059079" Enhanced Supported "Golgi apparatus,Perinuclear theca,Connecting piece,Principal piece" NA NA 4800 "Cluster 17: B-cells - Immunoglobulins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 39: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 126 "Golgi apparatus" "Perinuclear theca, Connecting piece, Principal piece" "CAB003791: , HPA049326: , HPA059079: " "unprognostic (8.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.41e-2)" "unprognostic (2.39e-3)" "unprognostic (1.47e-1)" "unprognostic (2.33e-1)" "unprognostic (3.53e-3)" "unprognostic (1.78e-2)" "unprognostic (2.08e-3)" "unprognostic (1.12e-1)" "unprognostic (5.46e-2)" "unprognostic (8.86e-3)" "unprognostic (4.64e-3)" "unprognostic (4.55e-2)" "unprognostic (2.41e-1)" "unprognostic (3.79e-2)" "unprognostic (3.35e-1)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (1.73e-3)" "unprognostic (1.62e-1)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (1.05e-2)" "unprognostic (6.78e-2)" "unprognostic (2.11e-1)" "unprognostic (3.02e-2)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (2.34e-1)" "unprognostic (9.18e-2)" "unprognostic (3.14e-1)" CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 154.8" "Group enriched" "Detected in many" 4 "Megakaryocytes: 1873.0;Platelets: 5719.2" "Group enriched" "Detected in many" 4 "Megakaryocytes: 1873.0;Platelets: 5719.2" "Group enriched" "Detected in some" 4 "endothelial cell: 237.5;fibroblast: 64.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 48.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 48.8;neutrophil: 24.3" "Lineage enriched" "Detected in many" 15 "granulocytes: 48.8" "Cancer enhanced" "Detected in many" "cervical cancer: 65.0" "Adrenal gland - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Liver - Sinusoid Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 302581388.0;Capillaries: 342155926.8;Cardiomyocytes: 107840060.7" "Tissue enhanced" "Detected in all" "lung: 308731213.6" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 110000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 47: Platelets - Hemostasis" 9 "Plasma membrane" Cytosol "HPA039325: , HPA062122: " "unprognostic (2.07e-2)" "unprognostic (8.24e-3)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (5.34e-2)" "unprognostic (9.46e-2)" "unprognostic (1.45e-1)" "unprognostic (5.41e-2)" "unprognostic (7.79e-3)" "potential prognostic favorable (4.16e-11)" "unprognostic (1.10e-3)" "unprognostic (1.09e-1)" "unprognostic (5.63e-2)" "unprognostic (7.23e-3)" "unprognostic (1.28e-1)" "unprognostic (9.33e-2)" "unprognostic (4.55e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-1)" "unprognostic (4.76e-2)" "unprognostic (3.06e-1)" "unprognostic (2.36e-1)" "unprognostic (2.51e-1)" "unprognostic (7.86e-3)" "unprognostic (9.38e-3)" "unprognostic (6.55e-3)" "unprognostic (8.69e-2)" "unprognostic (2.14e-1)" "unprognostic (6.66e-2)" CBLB "Cbl-b, RNF56" ENSG00000114423 "Cbl proto-oncogene B" Q13191 3 105655461-105869552 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1315.0;Extravillous trophoblasts: 962.4;Fibro-adipogenic progenitors: 902.5;NK-cells: 1303.7;Podocytes: 2392.1;T-cells: 1313.7;Thymic myoid cells: 1195.1" "Cell type enhanced" "Detected in all" "Renal nephron cells: 2392.1" "Cell type enhanced" "Detected in all" "leukocyte: 1170.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1178941.4;T-cells: 705273.8" "Tissue enriched" "Detected in some" "bone marrow: 12417940.3" "HPA018327, HPA019880" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 57 Cytosol Nucleoplasm "HPA018327: , HPA019880: " "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (2.68e-2)" "unprognostic (7.01e-3)" "unprognostic (3.02e-1)" "unprognostic (3.21e-2)" "unprognostic (3.31e-2)" "unprognostic (2.66e-2)" "unprognostic (4.34e-2)" "unprognostic (4.03e-3)" "unprognostic (4.16e-2)" "unprognostic (1.78e-2)" "unprognostic (9.55e-2)" "unprognostic (7.42e-2)" "unprognostic (3.97e-2)" "unprognostic (7.15e-2)" "unprognostic (2.89e-3)" "unprognostic (1.31e-1)" "unprognostic (5.22e-2)" "unprognostic (1.32e-1)" "unprognostic (2.53e-1)" "unprognostic (3.74e-1)" "unprognostic (1.45e-2)" "unprognostic (4.36e-2)" "unprognostic (5.93e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (1.88e-1)" "unprognostic (1.64e-1)" "unprognostic (3.15e-2)" "unprognostic (2.11e-1)" CBLN1 ENSG00000102924 "Cerebellin 1 precursor" P23435 16 49277917-49281838 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "brain: 425.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 64.0;Early spermatids: 86.4;Late primary spermatocytes: 153.3;Late spermatids: 522.6" "Cell type enriched" "Detected in some" 8 "Spermatogenic cell types: 522.6" "Cell type enriched" "Detected in many" 12 "upper rhombic lip: 168.6" "Group enriched" "Detected in many" 4 "Testicular Germ Cell Tumor (TCGA): 8.0;Thyroid Carcinoma (TCGA): 15.5" "Region enriched" "Detected in all" 4 "cerebellum: 239.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 12.2;Neuroblastoma: 18.5" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 9 "cerebellum: 613.4" "Region enriched" "Detected in all" 13 "cerebellum: 493.5" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "liver: 4835847.0" HPA056335 Approved "Cytosol,Perinuclear theca,Calyx,Flagellar centriole,Mid piece,Principal piece" "Secreted in brain" "No annotated function" NA NA 2100000 "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 1: Neuronal - Visual perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Cytosol, Flagellar centriole, Mid piece, Principal piece" "Perinuclear theca, Calyx" "HPA056335: " "unprognostic (1.30e-1)" "unprognostic (6.76e-3)" "unprognostic (1.01e-1)" "unprognostic (1.14e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.69e-6)" "unprognostic (2.48e-2)" "unprognostic (1.94e-1)" "unprognostic (1.06e-1)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (7.33e-3)" "unprognostic (1.01e-2)" "unprognostic (1.91e-3)" "unprognostic (4.64e-1)" CBLN2 ENSG00000141668 "Cerebellin 2 precursor" Q8IUK8 18 72536680-72638521 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 38.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 120.5;Brain inhibitory neurons: 7.4;Epicardial cells: 22.7;Mesothelial cells: 35.1;Neuroendocrine cells: 13.8;Other brain neurons: 7.8;Retinal amacrine cells: 18.0;Somatotrophs: 9.0" "Group enriched" "Detected in some" 5 "Barrier epithelial cells: 35.1;Neuronal cells: 120.5" "Cell type enhanced" "Detected in many" "deep-layer intratelencephalic: 310.4;hippocampal CA1-3: 530.6;upper-layer intratelencephalic: 623.5" "Cancer enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 10.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 36.9;Sarcoma: 13.5" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 2849 "Astrocytes and Neuropil: 380183.5;Microglia and Neuropil: 325023.3;Neurons: 149596.4" "Tissue enriched" "Detected in single" 4317 "cerebral cortex: 431663.5" HPA056335 Approved "Cytosol,Perinuclear theca,Calyx,Flagellar centriole,Mid piece,Principal piece" "Secreted in brain" "No annotated function" NA NA 1200000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Cytosol, Flagellar centriole, Mid piece, Principal piece" "Perinuclear theca, Calyx" "HPA056335: " "unprognostic (3.35e-2)" "unprognostic (6.84e-2)" "unprognostic (1.74e-1)" "unprognostic (1.98e-3)" "unprognostic (3.50e-3)" "unprognostic (9.90e-2)" "unprognostic (5.34e-1)" "unprognostic (9.51e-2)" "unprognostic (5.29e-2)" "potential prognostic unfavorable (6.45e-4)" CBLN3 ENSG00000139899 "Cerebellin 3 precursor" Q6UW01 14 24426545-24430954 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "brain: 365.9" "Cell type enriched" "Detected in some" 7 "Brain excitatory neurons: 80.9" "Cell type enriched" "Detected in many" 7 "Neuronal cells: 80.9" "Cell type enriched" "Detected in many" 18 "upper rhombic lip: 190.6" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 12 "cerebellum: 199.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.5" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Region enriched" "Detected in many" 25 "cerebellum: 429.9" "Region enriched" "Detected in many" 43 "cerebellum: 596.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA041266 Enhanced Supported Approved Nucleoplasm "Secreted in brain" "No annotated function" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "HPA041266: " "unprognostic (6.43e-2)" "unprognostic (1.57e-1)" "unprognostic (2.66e-1)" "unprognostic (7.56e-2)" "unprognostic (5.37e-2)" "unprognostic (4.31e-1)" "unprognostic (3.63e-3)" "unprognostic (1.04e-3)" "unprognostic (1.56e-2)" "unprognostic (4.25e-3)" "unprognostic (8.44e-2)" "unprognostic (2.64e-2)" "unprognostic (1.46e-1)" "unprognostic (3.46e-2)" "unprognostic (1.33e-3)" "unprognostic (1.86e-2)" "unprognostic (4.41e-2)" "unprognostic (1.27e-1)" "unprognostic (1.47e-1)" "unprognostic (2.72e-1)" "unprognostic (2.90e-3)" "unprognostic (4.77e-2)" "unprognostic (1.05e-1)" "unprognostic (2.17e-1)" "unprognostic (1.80e-1)" "unprognostic (2.71e-2)" "unprognostic (5.23e-2)" "unprognostic (2.43e-2)" "unprognostic (9.78e-2)" "unprognostic (2.89e-2)" "unprognostic (7.16e-2)" CBLN4 "CBLNL1, dJ885A10.1" ENSG00000054803 "Cerebellin 4 precursor" Q9NTU7 20 55997357-56005519 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 16.8;brain: 15.6;epididymis: 8.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 15.5;Brain inhibitory neurons: 21.8;Epididymal basal cells: 20.9;Fibro-adipogenic progenitors: 7.4;Leydig cells: 4.8;Other brain neurons: 29.2;Peritubular myoid cells: 44.4" "Group enriched" "Detected in some" 4 "Basal cells: 20.9;Neuronal cells: 29.2;Stromal cells: 44.4" "Cell type enhanced" "Detected in many" "CGE interneuron: 72.3;midbrain-derived inhibitory: 49.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Fibroblasts, Pituitary gland - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 646 "Astrocytes and Neuropil: 39748.4;Microglia and Neuropil: 53517.3;Neurons: 100627.4" "Tissue enriched" "Detected in single" 2375 "cerebral cortex: 237496.6" "HPA056335, HPA074497" Supported Approved "Cytosol,Perinuclear theca,Calyx,Flagellar centriole,Mid piece,Principal piece" "Secreted in brain" "No annotated function" NA NA 9200000 "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 98: Neurons - Neurotransmission & signaling" 60 "Cytosol, Flagellar centriole, Mid piece, Principal piece" "Perinuclear theca, Calyx" "HPA056335: , HPA074497: " "unprognostic (1.10e-1)" "unprognostic (1.41e-1)" "unprognostic (2.89e-2)" "unprognostic (9.06e-2)" "unprognostic (2.32e-2)" "unprognostic (7.39e-3)" "unprognostic (4.23e-1)" "unprognostic (4.60e-2)" CBR3 SDR21C2 ENSG00000159231 "Carbonyl reductase 3" O75828 21 36135079-36146562 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 64.8;salivary gland: 46.3" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 150.5;Esophageal apical cells: 285.6;Esophageal basal cells: 205.5;Esophageal suprabasal cells: 375.5;Salivary acinar cells: 153.6;Salivary ionocytes: 178.0;Submucosal glandular cells: 130.5;Suprabasal keratinocytes: 227.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 285.6;Suprabasal cells: 375.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 9 "B-cells: 24.1;NK-cells: 11.5;T-cells: 33.8" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 105.4" "Spleen - Fibroblasts_1" "Region enhanced" "Detected in all" "basal ganglia: 48.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "Keratinocytes: 94650939.0;Large ducts: 56108558.2;Proximal tubules: 78383678.0" "Low tissue specificity" "Detected in all" HPA018434 Uncertain Supported Nucleoplasm,Cytosol Yes NA 1200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 11 "Nucleoplasm, Cytosol" "HPA018434: " "unprognostic (6.27e-3)" "unprognostic (2.83e-3)" "unprognostic (1.12e-1)" "unprognostic (2.96e-2)" "unprognostic (4.66e-2)" "unprognostic (8.75e-2)" "unprognostic (1.92e-1)" "unprognostic (2.64e-1)" "unprognostic (4.65e-3)" "unprognostic (6.20e-2)" "unprognostic (2.87e-3)" "unprognostic (2.47e-1)" "unprognostic (7.26e-2)" "unprognostic (6.73e-2)" "unprognostic (2.34e-1)" "unprognostic (6.24e-2)" "unprognostic (3.54e-3)" "unprognostic (2.43e-2)" "unprognostic (2.24e-1)" "unprognostic (2.10e-1)" "unprognostic (3.28e-2)" "unprognostic (1.75e-1)" "unprognostic (7.00e-3)" "unprognostic (2.73e-1)" "unprognostic (1.59e-1)" "unprognostic (9.44e-2)" "unprognostic (9.93e-2)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "unprognostic (2.37e-2)" "unprognostic (3.14e-2)" CBY3 ENSG00000204659 "Chibby family member 3" A6NI87 5 179678560-179681034 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 12.3" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Bergmann glia: 2.4;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 3.0;Distal convoluted tubule cells: 1.2;Ependymal cells: 1.6;Loop of henle epithelial cells: 2.0;Microglia: 1.6;Oligodendrocyte progenitor cells: 1.9;Oligodendrocytes: 2.1;Other brain neurons: 2.8;Papillary tip epithelial cells: 3.1;Renal collecting duct intercalated cells: 1.1;Renal collecting duct principal cells: 3.1" "Group enriched" "Detected in some" 5 "Ciliated cells: 1.6;Ductal cells: 3.1;Glial cells: 2.4;Neuronal cells: 3.0;Renal nephron cells: 3.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA069037 Uncertain Approved Nucleoplasm NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "HPA069037: " CCDC102A MGC10992 ENSG00000135736 "Coiled-coil domain containing 102A" Q96A19 16 57512181-57536571 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 25.8;Peritubular myoid cells: 32.6;Respiratory ciliated cells: 25.1;Smooth muscle cells: 27.2" "Cell type enhanced" "Detected in many" "Stromal cells: 32.6" "Cell type enhanced" "Detected in some" "ependymal cell: 9.0;leukocyte: 8.8;pericyte: 8.8;vascular associated smooth muscle cell: 11.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 1662616.7;Smooth muscle cells: 2723935.8" "Tissue enhanced" "Detected in some" "lung: 481009.7" "HPA040598, HPA040958" Supported Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 Nucleoplasm "Nuclear bodies" "HPA040598: , HPA040958: " "unprognostic (1.61e-1)" "unprognostic (5.18e-2)" "unprognostic (2.65e-1)" "unprognostic (2.23e-2)" "unprognostic (5.58e-2)" "unprognostic (3.92e-2)" "unprognostic (1.56e-1)" "unprognostic (1.72e-1)" "unprognostic (3.20e-1)" "potential prognostic favorable (8.21e-4)" "unprognostic (1.44e-2)" "unprognostic (2.68e-1)" "unprognostic (4.00e-3)" "unprognostic (3.87e-1)" "unprognostic (1.25e-1)" "unprognostic (6.32e-2)" "unprognostic (2.23e-1)" "unprognostic (1.82e-3)" "unprognostic (3.49e-3)" "unprognostic (4.50e-2)" "unprognostic (2.24e-1)" "unprognostic (1.43e-1)" "unprognostic (7.59e-2)" "unprognostic (2.72e-2)" "unprognostic (6.17e-2)" "unprognostic (2.15e-2)" "unprognostic (2.12e-1)" "unprognostic (2.41e-1)" "unprognostic (1.70e-1)" "unprognostic (9.59e-2)" "unprognostic (3.06e-2)" CCDC106 HSU79303 ENSG00000173581 "Coiled-coil domain containing 106" Q9BWC9 19 55641062-55653161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 68.7" "Cell type enhanced" "Detected in many" "Oocytes: 50.7;Undifferentiated spermatogonia: 44.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 9.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 1413273.0" "Not detected" "Not detected" "HPA041925, HPA043219" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 23 Nucleoplasm Cytosol "HPA041925: , HPA043219: " "unprognostic (3.71e-2)" "unprognostic (1.10e-2)" "unprognostic (3.63e-1)" "unprognostic (3.83e-2)" "unprognostic (2.38e-1)" "unprognostic (3.10e-2)" "unprognostic (4.05e-2)" "unprognostic (2.28e-3)" "unprognostic (1.64e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (8.84e-9)" "unprognostic (7.90e-2)" "potential prognostic favorable (2.62e-5)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (1.22e-1)" "unprognostic (2.36e-1)" "unprognostic (3.64e-2)" "unprognostic (3.57e-2)" "unprognostic (1.85e-1)" "unprognostic (7.34e-2)" "potential prognostic favorable (1.08e-4)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-2)" "unprognostic (1.61e-2)" "unprognostic (9.24e-2)" "unprognostic (1.84e-1)" "unprognostic (3.62e-2)" "unprognostic (3.64e-2)" "unprognostic (8.38e-2)" CCDC120 JM11 ENSG00000147144 "Coiled-coil domain containing 120" Q96HB5 X 49053572-49069857 "Cancer-related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.6;skin 1: 28.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 114.9;Esophageal suprabasal cells: 53.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 114.9;Suprabasal cells: 53.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Keratinocytes: 24707.0;Microglia and Neuropil: 9542.8" "Tissue enriched" "Detected in single" 1647 "cerebral cortex: 164747.1" HPA000561 Uncertain Mitochondria NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 119 Mitochondria "HPA000561: " "unprognostic (6.80e-3)" "unprognostic (9.84e-3)" "unprognostic (1.56e-1)" "unprognostic (7.19e-3)" "unprognostic (1.38e-1)" "unprognostic (1.36e-1)" "unprognostic (1.68e-3)" "unprognostic (2.93e-3)" "unprognostic (1.16e-2)" "unprognostic (2.56e-1)" "unprognostic (2.22e-2)" "unprognostic (3.14e-1)" "unprognostic (7.88e-2)" "unprognostic (2.77e-3)" "unprognostic (7.57e-3)" "unprognostic (1.98e-1)" "unprognostic (3.21e-1)" "unprognostic (2.98e-1)" "unprognostic (1.13e-2)" "unprognostic (2.03e-1)" "unprognostic (2.18e-1)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.54e-1)" "unprognostic (1.17e-1)" "unprognostic (6.38e-3)" "unprognostic (2.45e-2)" "unprognostic (2.96e-2)" "unprognostic (1.60e-1)" "unprognostic (6.93e-2)" "unprognostic (2.41e-2)" CCDC126 FLJ23031 ENSG00000169193 "Coiled-coil domain containing 126" Q96EE4 7 23597382-23644708 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 32.5" "Group enriched" "Detected in many" 4 "Early spermatids: 783.0;Late primary spermatocytes: 254.4;Late spermatids: 762.3" "Cell type enriched" "Detected in all" 5 "Spermatogenic cell types: 783.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "basophil: 480.6" "Lineage enriched" "Detected in all" 23 "granulocytes: 480.6" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Large ducts: 247006.8;Pancreas epithelial cells: 433580.1" "Group enriched" "Detected in many" "bone marrow: 278356.8;liver: 158973.1;ovary: 76058.1" "HPA010969, HPA026883" Uncertain Approved "Golgi apparatus" "Secreted to blood" "No annotated function" NA NA 10000000 "Cluster 46: Basophils - Proteolysis" "Cluster 6: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "Golgi apparatus" "HPA010969: , HPA026883: " "unprognostic (1.09e-2)" "unprognostic (6.74e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (5.53e-2)" "unprognostic (1.92e-2)" "unprognostic (3.37e-2)" "unprognostic (6.88e-2)" "unprognostic (7.34e-2)" "unprognostic (6.97e-2)" "potential prognostic favorable (3.57e-5)" "unprognostic (3.10e-3)" "unprognostic (7.30e-2)" "unprognostic (9.22e-2)" "unprognostic (3.43e-2)" "unprognostic (3.29e-1)" "unprognostic (7.42e-2)" "unprognostic (1.07e-1)" "unprognostic (1.71e-1)" "unprognostic (3.59e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (5.08e-2)" "unprognostic (2.72e-1)" "unprognostic (2.91e-1)" "unprognostic (1.13e-1)" "unprognostic (3.50e-2)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (1.14e-1)" "unprognostic (3.55e-2)" "unprognostic (4.32e-1)" CCDC137 MGC16597 ENSG00000185298 "Coiled-coil domain containing 137" Q6PK04 17 81666737-81673904 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 107.6;Esophageal basal cells: 92.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 484982.0;Macrophages: 154839.0;Oocytes: 210866.0;T-cells: 618053.2" "Tissue enriched" "Detected in some" "lymphoid tissue: 69822.0" "HPA053914, HPA072411" Uncertain Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 68 Nucleoli "Nucleoplasm, Mitotic chromosome" "HPA053914: , HPA072411: " "unprognostic (7.29e-2)" "unprognostic (1.20e-2)" "unprognostic (1.01e-1)" "unprognostic (2.89e-1)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (1.47e-1)" "unprognostic (4.69e-1)" "unprognostic (2.08e-1)" "unprognostic (5.18e-2)" "validated prognostic unfavorable (2.80e-7)" "validated prognostic unfavorable (3.32e-4)" "unprognostic (1.95e-1)" "validated prognostic unfavorable (1.90e-9)" "validated prognostic unfavorable (4.55e-4)" "validated prognostic unfavorable (2.98e-4)" "validated prognostic unfavorable (1.79e-4)" "unprognostic (1.17e-1)" "unprognostic (1.45e-2)" "unprognostic (8.01e-2)" "unprognostic (6.56e-3)" "unprognostic (1.58e-1)" "unprognostic (6.69e-3)" "unprognostic (3.52e-2)" "unprognostic (6.19e-2)" "unprognostic (1.51e-1)" "unprognostic (5.56e-3)" "unprognostic (7.88e-2)" "unprognostic (2.85e-1)" "unprognostic (9.16e-2)" "unprognostic (1.88e-2)" CCDC14 "DKFZp434L1050, FLJ12892" ENSG00000175455 "Coiled-coil domain containing 14" Q49A88 3 123897305-123961408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Tuft cells: 403.5" "Cell type enhanced" "Detected in all" "Secretory gland support: 403.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 666 "Fallopian tube cells: 59633.1;Granulosa cells: 41209.7;Oocytes: 98822.6" "Not detected" "Not detected" "HPA035278, HPA035279" Uncertain Enhanced "Microtubules,Primary cilium,Centriolar satellite,Basal body" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 28: Astrocytes - Homeostasis & neuron support" 36 "Centriolar satellite" "Microtubules, Primary cilium, Basal body" "HPA035278: , HPA035279: " "unprognostic (5.08e-1)" "unprognostic (1.47e-1)" "unprognostic (1.36e-1)" "unprognostic (1.80e-2)" "unprognostic (1.10e-1)" "unprognostic (5.24e-2)" "unprognostic (8.13e-2)" "unprognostic (5.64e-2)" "unprognostic (1.95e-3)" "unprognostic (7.81e-3)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (2.80e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-3)" "unprognostic (1.24e-1)" "unprognostic (1.55e-1)" "unprognostic (3.64e-1)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (1.26e-1)" "unprognostic (1.31e-1)" "unprognostic (4.84e-2)" "unprognostic (2.15e-3)" "unprognostic (2.33e-3)" "potential prognostic favorable (3.62e-4)" "unprognostic (5.60e-2)" "unprognostic (4.20e-2)" "unprognostic (1.32e-2)" "unprognostic (3.09e-1)" "unprognostic (2.54e-1)" "unprognostic (3.26e-2)" CCDC148 MGC125588 ENSG00000153237 "Coiled-coil domain containing 148" Q8NFR7 2 158171073-158456753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 255.4;Distal convoluted tubule cells: 501.4;Ependymal cells: 255.7;Loop of henle epithelial cells: 388.9;Pituicytes/FSCs: 178.7;Pituitary stem cells: 168.5;Podocytes: 294.2;Respiratory ciliated cells: 281.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 281.2;Renal nephron cells: 501.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 239 "intestine: 23940.7" HPA042626 Uncertain Uncertain "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 5 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA042626: " "unprognostic (1.14e-1)" "unprognostic (9.22e-3)" "potential prognostic favorable (4.74e-4)" "unprognostic (6.51e-2)" "unprognostic (5.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.45e-1)" "unprognostic (2.09e-2)" CCDC15 FLJ13215 ENSG00000149548 "Coiled-coil domain containing 15" Q0P6D6 11 124954121-125041489 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 9.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 120.4;Early spermatids: 64.7;Erythrocyte progenitors: 70.0;Late primary spermatocytes: 74.1;Late spermatids: 62.4;Megakaryocyte progenitors: 38.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 70.0;Spermatogenic cell types: 120.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 199222.2" "Tissue enriched" "Detected in single" 725 "fallopian tube: 72502.0" "HPA040450, HPA041738" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" "Plasma membrane" Cytosol "HPA040450: , HPA041738: " "unprognostic (2.28e-1)" "unprognostic (5.71e-2)" "unprognostic (1.15e-1)" "unprognostic (2.50e-1)" "unprognostic (1.44e-1)" "unprognostic (2.50e-1)" "unprognostic (2.86e-3)" "potential prognostic favorable (4.56e-4)" "unprognostic (1.24e-2)" "unprognostic (4.67e-1)" "unprognostic (3.57e-3)" "unprognostic (5.06e-2)" "unprognostic (1.34e-1)" "unprognostic (8.46e-2)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.47e-2)" "unprognostic (4.69e-3)" "unprognostic (2.42e-2)" "unprognostic (3.54e-2)" "unprognostic (4.09e-2)" "unprognostic (2.54e-1)" CCDC169 "C13orf38, LOC728591, RP11-251J8.1" ENSG00000242715 "Coiled-coil domain containing 169" A6NNP5 13 36222008-36297840 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "testis: 55.6" "Group enriched" "Detected in some" 5 "Early spermatids: 700.4;Late spermatids: 2736.9" "Cell type enriched" "Detected in some" 107 "Spermatogenic cell types: 2736.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10287 "Fallopian tube cells: 1028711.3" "Not detected" "Not detected" HPA040527 Approved "Nucleoplasm,Nuclear speckles,Vesicles" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" Nucleoplasm "Nuclear speckles, Vesicles" "HPA040527: " "unprognostic (1.86e-1)" "unprognostic (3.64e-2)" "unprognostic (5.56e-2)" "unprognostic (2.30e-1)" "unprognostic (1.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.12e-1)" "unprognostic (2.83e-2)" "unprognostic (1.25e-1)" "unprognostic (1.69e-2)" "unprognostic (1.13e-1)" "unprognostic (1.41e-1)" CCDC171 "bA536D16.1, bA778P13.1, C9orf93, Em:AL513423.1, FLJ39267, FLJ46740" ENSG00000164989 "Coiled-coil domain containing 171" Q6TFL3 9 15553043-16061663 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 233.6;Hematopoietic stem cells: 329.0" "Cell type enhanced" "Detected in many" "Stem cells: 329.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Bone cancer: 8.2" "Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4917 "Hepatocytes: 491701.2" "Tissue enriched" "Detected in single" 533 "heart muscle: 53307.4" "HPA019803, HPA019806, HPA024133" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Nucleoplasm Nucleoli "HPA019803: , HPA019806: , HPA024133: " "unprognostic (7.02e-3)" "unprognostic (1.75e-2)" "unprognostic (1.39e-2)" "unprognostic (1.96e-1)" "unprognostic (2.12e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.78e-1)" "unprognostic (4.70e-2)" "unprognostic (4.30e-2)" "unprognostic (3.09e-1)" "unprognostic (1.17e-1)" "unprognostic (3.82e-2)" "unprognostic (1.35e-2)" "unprognostic (6.98e-2)" "unprognostic (1.31e-1)" "unprognostic (2.28e-2)" "unprognostic (1.54e-1)" CCDC181 "C1orf114, FLJ25846" ENSG00000117477 "Coiled-coil domain containing 181" Q5TID7 1 169394870-169460669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 30.6;retina: 37.0;testis: 24.6" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 121.8;Early spermatids: 264.1;Epididymal efferent duct ciliated cells: 121.3;Fallopian tube ciliated cells: 165.7;Late primary spermatocytes: 379.6;Respiratory ciliated cells: 173.0;Rod photoreceptor cells: 116.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 173.0;Neuronal cells: 116.5;Spermatogenic cell types: 379.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 1.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 1.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 6.8" "Adrenal gland - Adrenal medulla cells, Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 90546 "Fallopian tube cells: 9054578.3" "Tissue enriched" "Detected in single" 41541 "fallopian tube: 4154126.7" "HPA027189, HPA027275, HPA027281, HPA027312" Enhanced Approved "Nuclear speckles,Acrosome,Mid piece,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" "Nuclear speckles, Acrosome, Mid piece" "Principal piece" "HPA027189: , HPA027275: , HPA027281: , HPA027312: " "unprognostic (3.22e-2)" "unprognostic (8.22e-2)" "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "unprognostic (1.75e-3)" "unprognostic (4.97e-2)" "unprognostic (5.64e-2)" "unprognostic (1.39e-1)" "unprognostic (2.65e-1)" "unprognostic (7.06e-2)" "unprognostic (2.10e-1)" "unprognostic (8.16e-2)" "unprognostic (2.72e-2)" "unprognostic (3.04e-2)" "unprognostic (2.84e-2)" CCDC183 "bA216L13.7, KIAA1984, MGC15438" ENSG00000213213 "Coiled-coil domain containing 183" Q5T5S1 9 136796338-136807741 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 23.3" "Group enriched" "Detected in some" 13 "Early spermatids: 189.2;Late primary spermatocytes: 84.5;Late spermatids: 165.9" "Cell type enriched" "Detected in many" 17 "Spermatogenic cell types: 189.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 5 "dendritic cells: 1.4" "Low cancer specificity" "Detected in some" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" "Neutrophils: 1237145.9;T-cells: 435291.8" "Tissue enriched" "Detected in single" 4730 "fallopian tube: 473033.2" HPA043812 Uncertain Approved "Nucleoplasm,Primary cilium tip,Cytosol,Mid piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Nucleoplasm, Cytosol" "Primary cilium tip, Mid piece" "HPA043812: " "unprognostic (7.82e-3)" "unprognostic (2.18e-1)" "unprognostic (3.01e-3)" "unprognostic (1.02e-1)" "unprognostic (1.47e-1)" "unprognostic (8.04e-3)" "unprognostic (2.72e-1)" "unprognostic (2.26e-3)" CCDC184 "C12orf68, LOC387856" ENSG00000177875 "Coiled-coil domain containing 184" Q52MB2 12 48183644-48185926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.1;Decidual stromal cells: 52.0;Early spermatids: 69.6;Granulosa cells: 41.4;Late primary spermatocytes: 37.6;Late spermatids: 16.8;Other brain neurons: 13.6;Pancreatic islet cells: 15.3;Respiratory ciliated cells: 18.0" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 41.4;Spermatogenic cell types: 69.6;Stromal cells: 52.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 2.4;Neuroblastoma: 6.4;Rhabdoid: 8.0;Sarcoma: 2.3" "Colon - Colon enteroendocrine cells, Liver - Vascular endothelial cells, Spleen - Fibroblasts_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 146072.0" "Tissue enriched" "Detected in single" 172 "cerebral cortex: 17157.0" "HPA039947, HPA041715" Uncertain Approved Mitochondria,Cytosol No No "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 9 "Mitochondria, Cytosol" "HPA039947: , HPA041715: " "unprognostic (2.11e-1)" "unprognostic (1.88e-3)" "unprognostic (2.01e-2)" "unprognostic (1.88e-3)" "unprognostic (2.02e-3)" "unprognostic (1.16e-2)" "unprognostic (1.57e-1)" "unprognostic (1.01e-1)" "unprognostic (8.00e-3)" "unprognostic (3.88e-1)" "unprognostic (1.50e-3)" "unprognostic (6.51e-2)" "unprognostic (2.53e-1)" CCDC24 MGC45441 ENSG00000159214 "Coiled-coil domain containing 24" Q8N4L8 1 43991359-43996528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 84.3;Late primary spermatocytes: 78.7;Respiratory ciliated cells: 96.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 96.9;Spermatogenic cell types: 78.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 1.0;intermediate monocyte: 2.2;memory B-cell: 3.5;naive B-cell: 2.3;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 5 "B-cells: 3.5;granulocytes: 1.0;monocytes: 2.2" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035424, HPA061710" Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 30 "Plasma membrane" "Nucleoli, Cytosol" "HPA035424: , HPA061710: " "unprognostic (1.10e-1)" "potential prognostic favorable (9.32e-4)" "unprognostic (1.87e-1)" "unprognostic (4.40e-2)" "unprognostic (1.87e-1)" "unprognostic (1.02e-2)" "unprognostic (1.51e-3)" "unprognostic (6.96e-2)" "unprognostic (1.04e-1)" "unprognostic (1.57e-1)" "unprognostic (3.02e-2)" "unprognostic (3.28e-2)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (2.22e-1)" "unprognostic (4.40e-2)" "unprognostic (1.53e-1)" "unprognostic (4.55e-2)" "unprognostic (3.01e-1)" "unprognostic (2.50e-1)" "unprognostic (5.77e-2)" "unprognostic (1.18e-2)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "unprognostic (2.05e-2)" "unprognostic (4.87e-2)" "unprognostic (2.30e-1)" "unprognostic (3.34e-2)" "unprognostic (2.41e-1)" "unprognostic (5.58e-2)" "unprognostic (1.34e-1)" CCDC32 "C15orf57, MGC20481" ENSG00000128891 "Coiled-coil domain containing 32" Q9BV29 15 40528683-40565054 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Ciliopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 426031.4" "Tissue enhanced" "Detected in many" "lymphoid tissue: 253265.5" "HPA041360, HPA041688" Uncertain Approved "Plasma membrane,Microtubules,Primary cilium,Centrosome,Basal body" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 "Plasma membrane" "Microtubules, Primary cilium, Centrosome, Basal body" "HPA041360: , HPA041688: " "unprognostic (5.68e-3)" "unprognostic (2.12e-2)" "unprognostic (9.72e-2)" "unprognostic (6.67e-2)" "unprognostic (9.87e-2)" "unprognostic (1.56e-2)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (2.59e-1)" "validated prognostic favorable (3.26e-4)" "validated prognostic favorable (1.15e-4)" "unprognostic (7.80e-2)" "unprognostic (2.64e-2)" "unprognostic (1.52e-2)" "unprognostic (2.96e-3)" "unprognostic (1.96e-1)" "unprognostic (1.23e-1)" "unprognostic (6.71e-2)" "unprognostic (9.84e-2)" "unprognostic (1.78e-2)" "unprognostic (6.64e-3)" "unprognostic (2.17e-2)" "unprognostic (2.31e-2)" "unprognostic (1.95e-1)" "unprognostic (6.14e-2)" "unprognostic (6.61e-2)" "unprognostic (1.91e-1)" "unprognostic (2.72e-1)" "unprognostic (2.93e-2)" CCDC34 "L15, NY-REN-41, RAMA3" ENSG00000109881 "Coiled-coil domain containing 34" Q96HJ3 11 27330827-27363234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 48.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 271.9;Early primary spermatocytes: 211.5;Early spermatids: 324.2;Endometrial ciliated cells: 150.8;Epididymal efferent duct ciliated cells: 168.7;Late primary spermatocytes: 606.6;Oocytes: 152.0;Undifferentiated spermatogonia: 156.4" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 606.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5772 "Fallopian tube cells: 577241.4" "Tissue enriched" "Detected in single" 90 "fallopian tube: 8978.9" HPA037574 Uncertain Approved "Nuclear membrane,Nucleoli fibrillar center,Calyx,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 24: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 27: Non-specific - Cell proliferation" "Nuclear membrane, Nucleoli fibrillar center, Calyx, Mid piece" "Connecting piece, Principal piece, End piece" "HPA037574: " "unprognostic (2.41e-2)" "unprognostic (7.12e-2)" "unprognostic (2.69e-1)" "unprognostic (2.74e-2)" "unprognostic (2.19e-1)" "unprognostic (4.75e-2)" "unprognostic (9.60e-3)" "unprognostic (3.40e-1)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (6.53e-4)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (1.66e-4)" "validated prognostic unfavorable (2.31e-8)" "validated prognostic unfavorable (1.34e-5)" "potential prognostic unfavorable (2.83e-5)" "unprognostic (8.76e-3)" "unprognostic (7.03e-3)" "unprognostic (5.22e-2)" "unprognostic (5.62e-3)" "unprognostic (8.55e-2)" "unprognostic (1.71e-2)" "unprognostic (6.92e-3)" "unprognostic (8.39e-2)" "unprognostic (1.79e-2)" "unprognostic (1.27e-1)" "unprognostic (2.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.49e-1)" "unprognostic (3.42e-3)" "unprognostic (7.02e-2)" CCDC39 "CFAP59, CILD14, DKFZp434A128, FAP59" ENSG00000284862 "Coiled-coil domain containing 39" Q9UFE4 3 180602858-180684942 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.2;retina: 20.2;skin 1: 19.1" "Group enriched" "Detected in many" 4 "Adipocytes: 113.6;Cardiomyocytes: 282.7;Epicardial cells: 222.9" "Group enriched" "Detected in many" 4 "Adipocytes: 113.6;Barrier epithelial cells: 222.9;Myocytes: 282.7" "Cell type enhanced" "Detected in all" "ependymal cell: 50.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 102357 "Fallopian tube cells: 10235714.6" "Tissue enriched" "Detected in single" 189208 "fallopian tube: 18920753.3" "HPA035363, HPA035364" Enhanced Uncertain "Nucleoplasm,Centrosome,Basal body,Acrosome" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "Nucleoplasm, Centrosome, Basal body, Acrosome" "HPA035363: , HPA035364: " "unprognostic (8.67e-3)" "unprognostic (2.06e-1)" "unprognostic (7.96e-2)" "unprognostic (4.98e-2)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (9.77e-2)" "potential prognostic favorable (3.46e-4)" "unprognostic (3.03e-2)" "unprognostic (4.77e-2)" "unprognostic (2.41e-1)" "unprognostic (6.26e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.51e-1)" "potential prognostic favorable (6.68e-6)" "unprognostic (1.29e-1)" "unprognostic (2.65e-1)" "unprognostic (5.45e-3)" "unprognostic (2.84e-3)" "unprognostic (1.10e-1)" "unprognostic (9.70e-2)" "unprognostic (9.97e-2)" "unprognostic (3.18e-1)" "unprognostic (7.43e-3)" "unprognostic (1.24e-1)" CCDC40 "CFAP172, CILD15, FAP172, FLJ20753, FLJ32021, KIAA1640" ENSG00000141519 "Coiled-coil domain containing 40" Q4G0X9 17 80036632-80100613 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.7;fallopian tube: 14.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 238.4;Endometrial ciliated cells: 190.4;Ependymal cells: 298.7;Epididymal efferent duct ciliated cells: 153.2;Fallopian tube ciliated cells: 212.5;Respiratory ciliated cells: 301.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 301.7" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 181.2;ependymal cell: 301.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 239409 "Fallopian tube cells: 23940875.2" "Tissue enriched" "Detected in single" 157053 "fallopian tube: 15705300.8" HPA022974 Enhanced Approved "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "Microtubules, Primary cilium, Cytosol" "Cytokinetic bridge, Mid piece" "HPA022974: " "unprognostic (7.37e-3)" "unprognostic (2.60e-2)" "unprognostic (4.52e-2)" "unprognostic (5.11e-3)" "unprognostic (6.03e-2)" "unprognostic (1.48e-1)" "unprognostic (9.98e-3)" "potential prognostic unfavorable (4.93e-4)" "unprognostic (1.62e-2)" "unprognostic (2.48e-3)" "unprognostic (2.39e-1)" "unprognostic (1.56e-2)" "unprognostic (3.11e-3)" "unprognostic (4.76e-2)" "unprognostic (1.92e-2)" "unprognostic (1.85e-1)" "unprognostic (5.00e-3)" "unprognostic (1.26e-1)" "unprognostic (4.18e-2)" "potential prognostic favorable (5.33e-4)" "potential prognostic favorable (9.62e-4)" "unprognostic (6.14e-3)" "unprognostic (2.17e-2)" "unprognostic (2.24e-2)" "unprognostic (9.84e-2)" "unprognostic (2.16e-1)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (1.34e-3)" "unprognostic (1.36e-2)" CCDC6 "D10S170, H4, PTC, TPC, TST1" ENSG00000108091 "Coiled-coil domain containing 6" Q16204 10 59788747-59906556 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 376.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA019049, HPA019051" Enhanced Supported Cytosol No No 6200 "Cluster 23: B-cells - Immunoglobulins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 71 Cytosol "HPA019049: , HPA019051: " "unprognostic (5.88e-2)" "unprognostic (1.95e-2)" "unprognostic (1.16e-1)" "unprognostic (1.46e-1)" "unprognostic (1.54e-1)" "unprognostic (2.88e-2)" "unprognostic (3.56e-2)" "unprognostic (3.45e-3)" "unprognostic (1.36e-2)" "unprognostic (2.95e-2)" "potential prognostic favorable (3.51e-6)" "unprognostic (2.87e-1)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (9.10e-4)" "unprognostic (2.72e-3)" "unprognostic (4.24e-2)" "unprognostic (4.39e-2)" "unprognostic (3.31e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (9.13e-3)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (2.84e-1)" "unprognostic (5.78e-2)" "unprognostic (9.75e-2)" "unprognostic (4.65e-1)" "unprognostic (1.58e-1)" "unprognostic (3.81e-1)" "unprognostic (4.37e-1)" "unprognostic (4.74e-2)" "unprognostic (7.20e-2)" CCDC63 "FLJ35843, ODA5" ENSG00000173093 "Coiled-coil domain containing 63" Q8NA47 12 110846769-110907535 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 16.6" "Group enriched" "Detected in some" 12 "Early spermatids: 395.4;Late primary spermatocytes: 227.1;Late spermatids: 389.5" "Cell type enriched" "Detected in some" 14 "Spermatogenic cell types: 395.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA043927 Approved "Nucleoplasm,Cell Junctions,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nucleoplasm, Principal piece" "Cell Junctions" "HPA043927: " CCDC66 DKFZp686C0433 ENSG00000180376 "Coiled-coil domain containing 66" A2RUB6 3 56557161-56621837 "Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044185, HPA051937" Approved Supported "Vesicles,Plasma membrane,Cell Junctions,Midbody ring,Primary cilium,Centriolar satellite,Cytosol,Perinuclear theca,End piece" Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 4 "Primary cilium, Centriolar satellite, Perinuclear theca" "Vesicles, Plasma membrane, Cell Junctions, Midbody ring, Cytosol, End piece" "HPA044185: , HPA051937: " "unprognostic (4.04e-1)" "unprognostic (2.43e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.16e-1)" "unprognostic (3.46e-1)" "unprognostic (1.10e-1)" "unprognostic (3.44e-2)" "unprognostic (3.78e-2)" "unprognostic (8.34e-3)" "unprognostic (1.82e-2)" "unprognostic (3.26e-2)" "unprognostic (4.65e-2)" "unprognostic (1.97e-1)" "unprognostic (6.77e-2)" "unprognostic (1.60e-1)" "unprognostic (4.37e-2)" "unprognostic (4.70e-2)" "unprognostic (2.23e-1)" "unprognostic (1.92e-1)" "unprognostic (2.72e-1)" "unprognostic (3.49e-2)" "unprognostic (6.65e-2)" "unprognostic (1.47e-2)" "unprognostic (6.35e-3)" "unprognostic (1.07e-1)" "unprognostic (1.84e-1)" "unprognostic (1.43e-1)" "unprognostic (4.96e-2)" "unprognostic (1.08e-1)" CCDC68 SE57-1 ENSG00000166510 "Coiled-coil domain containing 68" Q9H2F9 18 54901509-54959461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3;placenta: 30.5" "Cell type enhanced" "Detected in many" "Colonocytes: 116.1;Early spermatids: 97.4;Enterocytes: 114.2;Epididymal clear cells: 81.7;Foveolar cells: 95.4;Goblet cells: 73.0;Prostatic glandular cells: 81.6;Salivary ionocytes: 118.3;Sertoli cells: 163.0;Somatotrophs: 166.9;Vascular endothelial cells: 95.1" "Cell type enhanced" "Detected in many" "Pituitary endocrine cells: 166.9;Reproductive supporting cells: 163.0" "Group enriched" "Detected in many" 5 "endothelial cell: 136.6;mammillary body: 42.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Pituitary gland - Somatotropes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 3118 "Alveolar cell types: 311788.8" "Tissue enriched" "Detected in single" 89 "lung: 8932.6" "HPA040865, HPA048197" Supported Approved "Golgi apparatus,Cytosol" No NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "Golgi apparatus" Cytosol "HPA040865: , HPA048197: " "unprognostic (1.22e-1)" "unprognostic (3.74e-2)" "unprognostic (1.32e-1)" "unprognostic (2.48e-3)" "unprognostic (5.59e-3)" "unprognostic (1.71e-1)" "unprognostic (7.90e-2)" "unprognostic (3.52e-1)" "unprognostic (1.60e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (9.70e-2)" "unprognostic (2.60e-2)" "unprognostic (1.73e-2)" "unprognostic (1.61e-1)" "unprognostic (2.18e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (6.83e-4)" "unprognostic (2.01e-2)" "unprognostic (1.74e-3)" "unprognostic (3.25e-2)" "unprognostic (2.87e-1)" "unprognostic (1.78e-2)" "unprognostic (9.47e-2)" "unprognostic (9.81e-3)" "unprognostic (4.88e-1)" "unprognostic (3.22e-1)" CCDC7 "BIOT2, C10orf68, FLJ13031, FLJ32762" ENSG00000216937 "Coiled-coil domain containing 7" Q96M83 10 32446140-32882874 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 29 "testis: 74.0" "Cell type enhanced" "Detected in many" "Early spermatids: 690.7;Late primary spermatocytes: 696.6;Late spermatids: 2169.9" "Cell type enriched" "Detected in many" 7 "Spermatogenic cell types: 2169.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 11258 "cerebral cortex: 1125756.0" HPA075536 Approved "Nucleoli,Mitotic spindle,Cytosol" Yes No "Cluster 1: T-cells - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 Nucleoli "Mitotic spindle, Cytosol" "HPA075536: " "unprognostic (2.70e-1)" "unprognostic (2.05e-1)" "unprognostic (3.30e-2)" "unprognostic (1.27e-3)" "unprognostic (2.55e-1)" "unprognostic (5.66e-2)" "unprognostic (2.56e-1)" "unprognostic (3.51e-3)" "unprognostic (3.12e-3)" "unprognostic (8.41e-2)" CCDC71 FLJ12800 ENSG00000177352 "Coiled-coil domain containing 71" Q8IV32 3 49162535-49166331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 28.9;Epididymal principal cells: 32.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 2273337.0" "Tissue enriched" "Detected in single" 79 "lymphoid tissue: 7907.9" HPA047547 Uncertain Approved "Nuclear membrane" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 75: Ovary - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 "Nuclear membrane" "HPA047547: " "unprognostic (5.66e-2)" "unprognostic (8.61e-2)" "unprognostic (9.47e-2)" "unprognostic (6.68e-3)" "unprognostic (8.42e-3)" "unprognostic (6.71e-3)" "unprognostic (9.85e-2)" "unprognostic (1.73e-2)" "unprognostic (1.08e-1)" "unprognostic (2.83e-2)" "potential prognostic favorable (1.05e-4)" "unprognostic (2.93e-2)" "potential prognostic favorable (9.90e-4)" "unprognostic (1.68e-3)" "unprognostic (1.33e-1)" "unprognostic (7.30e-3)" "unprognostic (1.91e-2)" "unprognostic (3.37e-1)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "unprognostic (1.59e-1)" "unprognostic (4.86e-2)" "unprognostic (2.13e-1)" "unprognostic (2.28e-1)" "unprognostic (6.04e-3)" "unprognostic (4.09e-1)" "unprognostic (3.74e-1)" "unprognostic (2.58e-1)" "unprognostic (1.33e-1)" "unprognostic (2.78e-1)" "unprognostic (9.30e-3)" CCDC81 "FLJ16339, FLJ23514" ENSG00000149201 "Coiled-coil domain containing 81" Q6ZN84 11 86374736-86423109 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 15.8;fallopian tube: 25.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 51.6;Endometrial ciliated cells: 115.8;Ependymal cells: 198.4;Epididymal efferent duct ciliated cells: 42.4;Extravillous trophoblasts: 40.8;Fallopian tube ciliated cells: 139.0;Late primary spermatocytes: 55.3;Migrating cytotrophoblasts: 46.2;Pituitary stem cells: 113.0;Respiratory ciliated cells: 123.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 198.4;Spermatogenic cell types: 55.3;Stem cells: 113.0;Trophoblast cells: 46.2" "Cell type enriched" "Detected in all" 4 "ependymal cell: 223.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 1.9" "Adipose subcutaneous - Smooth muscle cells, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4637 "Fallopian tube cells: 463684.3" "Tissue enriched" "Detected in single" 16640 "fallopian tube: 1664018.7" HPA040745 Approved "Plasma membrane,Basal body" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Plasma membrane, Basal body" "HPA040745: " "unprognostic (1.64e-2)" "unprognostic (3.57e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (1.95e-4)" "unprognostic (1.35e-2)" "unprognostic (4.98e-1)" CCDC82 FLJ23518 ENSG00000149231 "Coiled-coil domain containing 82" Q8N4S0 11 96349241-96389956 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 500.4;Late primary spermatocytes: 484.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 500.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 600125.2;T-cells: 2349758.6" "Tissue enriched" "Detected in single" 25 "lymphoid tissue: 2536.9" "HPA038704, HPA070631" Uncertain Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 Nucleoplasm "Nuclear bodies, Cytosol" "HPA038704: , HPA070631: " "unprognostic (1.11e-1)" "unprognostic (3.44e-1)" "unprognostic (7.76e-2)" "unprognostic (3.83e-2)" "unprognostic (5.71e-2)" "unprognostic (1.37e-1)" "unprognostic (8.87e-2)" "unprognostic (1.86e-1)" "unprognostic (8.95e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (7.67e-3)" "potential prognostic favorable (8.48e-4)" "unprognostic (2.50e-2)" "unprognostic (1.14e-2)" "unprognostic (3.38e-1)" "unprognostic (2.59e-1)" "unprognostic (1.33e-3)" "unprognostic (2.69e-1)" "unprognostic (8.28e-2)" "unprognostic (3.82e-2)" "unprognostic (1.98e-1)" "unprognostic (4.95e-3)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (3.64e-2)" "unprognostic (1.61e-2)" "unprognostic (6.24e-2)" "unprognostic (4.00e-1)" "unprognostic (1.49e-1)" "unprognostic (1.73e-1)" CCDC86 "cyclon, MGC2574" ENSG00000110104 "Coiled-coil domain containing 86" Q9H6F5 11 60842113-60851081 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "parathyroid gland: 355.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 30.9;Esophageal basal cells: 40.9;Late primary spermatocytes: 127.5;Oocytes: 41.4" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 127.5" "Cell type enhanced" "Detected in many" "fibroblast: 13.2;pericyte: 13.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 2916272.5;Granulosa cells: 825636.0;Macrophages: 1072151.6;T-cells: 2639312.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 3129297.8" "HPA041117, HPA041540" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 22 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA041117: , HPA041540: " "unprognostic (1.75e-1)" "unprognostic (1.86e-1)" "unprognostic (1.31e-1)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (4.30e-2)" "potential prognostic unfavorable (9.36e-6)" "unprognostic (1.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.56e-1)" "unprognostic (4.95e-2)" "validated prognostic unfavorable (1.44e-6)" "validated prognostic unfavorable (1.00e-5)" "validated prognostic unfavorable (9.37e-4)" "validated prognostic unfavorable (3.61e-4)" "unprognostic (4.08e-1)" "unprognostic (2.03e-2)" "unprognostic (5.46e-3)" "unprognostic (8.42e-2)" "unprognostic (2.37e-2)" "unprognostic (3.58e-2)" "unprognostic (1.23e-1)" "unprognostic (4.66e-2)" "unprognostic (2.42e-1)" "unprognostic (2.43e-1)" "unprognostic (1.49e-2)" "unprognostic (4.95e-1)" "unprognostic (4.37e-2)" "unprognostic (5.76e-2)" CCDC91 "DKFZp779L1558, FLJ11088, p56" ENSG00000123106 "Coiled-coil domain containing 91" Q7Z6B0 12 28133249-28581511 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 14270.4" "Cell type enriched" "Detected in all" 5 "Spermatogenic cell types: 14270.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 27751019.0" "Low tissue specificity" "Detected in many" HPA038169 Approved Approved "Nucleoplasm,Golgi apparatus,Acrosome,Equatorial segment,Flagellar centriole" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Nucleoplasm, Golgi apparatus, Acrosome" "Equatorial segment, Flagellar centriole" "HPA038169: " "unprognostic (2.53e-1)" "unprognostic (4.56e-3)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (1.98e-4)" "unprognostic (1.43e-3)" "unprognostic (6.31e-2)" "unprognostic (4.78e-2)" "unprognostic (1.00e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (1.33e-3)" "unprognostic (2.51e-3)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (3.59e-5)" "unprognostic (5.81e-2)" "unprognostic (1.71e-2)" "unprognostic (1.56e-1)" "unprognostic (1.26e-1)" "unprognostic (3.04e-1)" "unprognostic (1.06e-1)" "unprognostic (1.01e-2)" "unprognostic (1.29e-2)" "potential prognostic unfavorable (4.50e-5)" "unprognostic (2.11e-1)" "unprognostic (6.16e-2)" "potential prognostic favorable (2.55e-4)" "unprognostic (7.74e-3)" "unprognostic (7.36e-2)" "unprognostic (4.91e-2)" "unprognostic (2.46e-1)" "unprognostic (1.87e-1)" CCHCR1 "C6orf18, HCR" ENSG00000204536 "Coiled-coil alpha-helical rod protein 1" Q8TD31 6 31142439-31158238 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 129.4" "Cell type enhanced" "Detected in many" "Early spermatids: 56.6;Late primary spermatocytes: 96.4;Late spermatids: 174.5" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 174.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 1632645.4;Keratinocytes: 408435.9" "Tissue enriched" "Detected in single" 1543 "fallopian tube: 154255.2" HPA054167 Supported Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 28: Non-specific - Nuclear processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 40 Cytosol "HPA054167: " "unprognostic (2.01e-1)" "unprognostic (6.59e-2)" "unprognostic (2.25e-1)" "unprognostic (2.83e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.20e-1)" "unprognostic (5.86e-2)" "unprognostic (3.99e-2)" "unprognostic (1.40e-1)" "unprognostic (9.72e-3)" "unprognostic (7.57e-3)" "unprognostic (6.99e-2)" "unprognostic (5.72e-2)" "potential prognostic unfavorable (4.97e-5)" "unprognostic (2.50e-1)" "unprognostic (1.73e-2)" "unprognostic (1.80e-1)" "unprognostic (8.66e-3)" "unprognostic (2.17e-1)" "unprognostic (3.44e-2)" "unprognostic (5.29e-2)" "unprognostic (3.26e-2)" "unprognostic (7.67e-2)" "unprognostic (7.21e-2)" "unprognostic (1.19e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (8.13e-2)" "unprognostic (5.05e-2)" "unprognostic (7.97e-2)" CCL15 "HCC-2, HMRP-2B, Lkn-1, MIP-1d, MIP-5, NCC-3, SCYA15, SCYL3" ENSG00000275718 "C-C motif chemokine ligand 15" Q16663 17 35996440-36001553 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Chemotaxis "Cytokine, Heparin-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "intestine: 77.7;liver: 40.2" "Cell type enhanced" "Detected in some" "Colonocytes: 7.8;Enteric stem cells: 3.9;Enteric transient amplifying cells: 5.9;Enterocytes: 19.2;Fallopian tube ciliated cells: 1.9;Goblet cells: 7.8;Neuroendocrine cells: 2.6;Paneth cells: 3.9" "Cell type enhanced" "Detected in some" "Enterocytes: 19.2;Goblet cells: 7.8;Proliferating cells: 5.9;Secretory gland support: 3.9;Stem cells: 3.9" "Cell type enhanced" "Detected in single" "ependymal cell: 2.4" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 45.7;Liver Hepatocellular Carcinoma (TCGA): 63.8;Rectum Adenocarcinoma (TCGA): 44.4;Stomach Adenocarcinoma (TCGA): 21.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "colorectal cancer: 24.6;Gastric cancer: 10.9;liver cancer: 14.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046429, HPA058608" Approved "Golgi apparatus,Vesicles" "Secreted to blood" Chemokine NA NA 3270000 2700000 "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "Golgi apparatus" Vesicles "HPA046429: , HPA058608: " "unprognostic (4.66e-2)" "potential prognostic favorable (3.43e-4)" "unprognostic (1.80e-2)" "unprognostic (1.89e-1)" "unprognostic (1.55e-1)" "unprognostic (1.40e-1)" "unprognostic (1.97e-1)" "unprognostic (1.76e-2)" "unprognostic (3.64e-2)" "unprognostic (2.77e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" "unprognostic (1.06e-1)" "unprognostic (2.77e-2)" "unprognostic (6.08e-2)" "unprognostic (6.21e-2)" "unprognostic (3.14e-1)" CCN2 "CTGF, IGFBP8" ENSG00000118523 "Cellular communication network factor 2" P29279 6 131948176-131951372 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, DNA synthesis" Heparin-binding "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 1230.3" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 522.7;Endometrial glandular cells: 311.1;Endometrial luminal cells: 368.6;Epididymal efferent duct ciliated cells: 383.6;Fallopian tube ciliated cells: 322.5;Fibroblasts: 340.1;Hepatic stellate cells: 2033.3;Pancreatic duct cells: 628.1;Peritubular myoid cells: 439.4;Podocytes: 979.7;Respiratory ciliated cells: 317.4;Salivary myoepithelial cells: 361.8;Smooth muscle cells: 350.2;Vascular endothelial cells: 413.1" "Cell type enhanced" "Detected in many" "Ductal cells: 628.1;Renal nephron cells: 979.7;Stellate cells: 2033.3" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 109.0;endothelial cell: 185.1;vascular associated smooth muscle cell: 99.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive B-cell: 8.1" "Lineage enriched" "Detected in single" 81 "B-cells: 8.1" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Smooth muscle cells: 2034315.4" "Group enriched" "Detected in some" 9885 "blood vessel: 1636350.2;cerebral cortex: 888235.1;lymphoid tissue: 440765.3" "HPA002976, CAB005123, HPA031074, HPA031075" Approved Approved "Golgi apparatus,Vesicles" "Secreted in other tissues" "Cell adhesion" No No 8300000 "Cluster 34: B-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Golgi apparatus" Vesicles "CAB005123: , HPA002976: , HPA031074: , HPA031075: " "unprognostic (5.29e-2)" "unprognostic (1.96e-1)" "unprognostic (1.28e-1)" "unprognostic (9.13e-2)" "unprognostic (4.17e-2)" "unprognostic (9.66e-2)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (3.32e-2)" "unprognostic (9.15e-2)" "unprognostic (1.18e-1)" "unprognostic (3.41e-2)" "unprognostic (3.04e-2)" "unprognostic (2.96e-1)" "unprognostic (1.45e-1)" "unprognostic (2.01e-1)" "unprognostic (1.24e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.41e-2)" "unprognostic (2.64e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (2.99e-5)" "unprognostic (6.45e-2)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (1.70e-1)" "unprognostic (1.40e-2)" "unprognostic (5.95e-2)" CCNA2 "CCN1, CCNA" ENSG00000145386 "Cyclin A2" P20248 4 121816444-121823883 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 36.4;lymphoid tissue: 43.6;retina: 29.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 53.1;Differentiating spermatogonia: 37.5;Enteric transient amplifying cells: 60.2;Erythrocyte progenitors: 122.6;Esophageal basal cells: 51.3;Extravillous trophoblasts: 96.8;Hofbauer cells: 35.8;Megakaryocyte progenitors: 65.0;Megakaryocytes: 37.1;Migrating cytotrophoblasts: 91.5;Monocyte progenitors: 143.7;Neutrophil progenitors: 52.6;Oocytes: 46.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 122.6;Megakaryocytes: 65.0;Mononuclear phagocytes: 143.7;Trophoblast cells: 96.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 3.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Group enriched" "Detected in many" 4 "basal ganglia: 3.4;white matter: 7.6" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000114, HPA020626" Enhanced Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 98 "Nucleoplasm, Cytosol" "CAB000114: , HPA020626: " "unprognostic (2.72e-2)" "unprognostic (9.35e-2)" "unprognostic (1.35e-1)" "unprognostic (1.04e-2)" "unprognostic (9.85e-3)" "unprognostic (1.94e-1)" "unprognostic (1.33e-1)" "unprognostic (5.83e-3)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (3.24e-4)" "validated prognostic unfavorable (6.09e-7)" "validated prognostic unfavorable (4.21e-4)" "potential prognostic unfavorable (1.51e-5)" "validated prognostic unfavorable (1.55e-5)" "validated prognostic unfavorable (1.34e-6)" "validated prognostic unfavorable (5.17e-6)" "validated prognostic unfavorable (4.74e-4)" "unprognostic (2.62e-2)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (2.65e-3)" "unprognostic (1.70e-3)" "unprognostic (3.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (2.11e-1)" "unprognostic (1.14e-2)" "unprognostic (1.18e-1)" CCNB1 CCNB ENSG00000134057 "Cyclin B1" P14635 5 69167135-69178245 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.9;lymphoid tissue: 70.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 117.2;Enteric transient amplifying cells: 101.6;Erythrocyte progenitors: 121.3;Esophageal basal cells: 151.1;Extravillous trophoblasts: 893.1;Gastric progenitor cells: 108.9;Late primary spermatocytes: 147.9;Migrating cytotrophoblasts: 300.4;Monocyte progenitors: 105.5;Oocytes: 294.7" "Cell type enhanced" "Detected in many" "Oocytes: 294.7;Trophoblast cells: 893.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Group enriched" "Detected in many" 5 "basal ganglia: 3.0;white matter: 8.3" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 16012 "Granulosa cells: 1601163.6" "Not detected" "Not detected" "CAB000115, CAB003804, HPA030741, HPA061448" Enhanced Enhanced Cytosol Yes Yes "Cluster 14: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 100 Cytosol "CAB000115: , CAB003804: , HPA030741: , HPA061448: " "unprognostic (7.73e-3)" "unprognostic (1.97e-2)" "unprognostic (2.55e-2)" "unprognostic (2.62e-1)" "unprognostic (1.24e-2)" "unprognostic (9.57e-2)" "unprognostic (2.52e-1)" "unprognostic (1.64e-1)" "unprognostic (8.55e-2)" "potential prognostic unfavorable (5.21e-4)" "validated prognostic unfavorable (6.02e-4)" "validated prognostic unfavorable (2.79e-5)" "potential prognostic unfavorable (8.00e-10)" "validated prognostic unfavorable (1.01e-8)" "validated prognostic unfavorable (9.80e-9)" "validated prognostic unfavorable (4.62e-7)" "validated prognostic unfavorable (4.74e-4)" "unprognostic (2.29e-2)" "unprognostic (2.11e-1)" "unprognostic (1.89e-1)" "unprognostic (1.06e-1)" "unprognostic (1.85e-3)" "unprognostic (5.56e-3)" "unprognostic (1.42e-1)" "unprognostic (8.98e-2)" "unprognostic (5.97e-2)" "unprognostic (4.61e-3)" "unprognostic (1.73e-1)" "unprognostic (1.59e-1)" "unprognostic (2.28e-1)" "unprognostic (3.89e-1)" CCNB2 HsT17299 ENSG00000157456 "Cyclin B2" O95067 15 59105126-59125045 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 70.4;lymphoid tissue: 68.1;testis: 64.9" "Group enriched" "Detected in many" 4 "Late primary spermatocytes: 552.5;Oocytes: 336.2" "Group enriched" "Detected in many" 4 "Oocytes: 336.2;Spermatogenic cell types: 552.5" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 3.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "T-reg: 22.7" "Lineage enriched" "Detected in many" 6 "T-cells: 22.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1422 "Granulosa cells: 142201.3" "Not detected" "Not detected" "HPA008873, CAB009575" Enhanced Enhanced "Golgi apparatus,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 27 Cytosol "Golgi apparatus" "CAB009575: , HPA008873: " "unprognostic (1.35e-2)" "unprognostic (1.98e-2)" "unprognostic (5.48e-2)" "unprognostic (1.84e-1)" "unprognostic (1.77e-1)" "unprognostic (3.14e-1)" "unprognostic (6.72e-2)" "unprognostic (3.96e-2)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (1.33e-5)" "validated prognostic unfavorable (2.37e-9)" "validated prognostic unfavorable (4.98e-5)" "potential prognostic unfavorable (4.74e-13)" "validated prognostic unfavorable (7.26e-5)" "validated prognostic unfavorable (1.08e-7)" "validated prognostic unfavorable (4.65e-6)" "validated prognostic unfavorable (1.99e-4)" "unprognostic (2.66e-2)" "unprognostic (2.08e-1)" "unprognostic (1.85e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (3.54e-5)" "unprognostic (2.97e-3)" "unprognostic (9.01e-2)" "unprognostic (6.29e-3)" "unprognostic (9.09e-2)" "unprognostic (1.29e-3)" "unprognostic (2.90e-1)" "unprognostic (3.78e-1)" "unprognostic (1.77e-1)" "unprognostic (2.53e-1)" CCND1 "BCL1, D11S287E, PRAD1, U21B31" ENSG00000110092 "Cyclin D1" P24385 11 69641156-69654474 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, DNA damage, Transcription, Transcription regulation" "Cyclin, Repressor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 611.9;Epididymal efferent duct absorptive cells: 585.6;Esophageal suprabasal cells: 337.2;Fallopian secretory cells: 396.1;Ocular epithelial cells: 336.9;Pancreatic duct cells: 537.7;Respiratory secretory cells: 328.7;Suprabasal keratinocytes: 314.7" "Cell type enhanced" "Detected in many" "Alveolar cells: 611.9;Ductal cells: 585.6" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 60.4;choroid plexus epithelial cell: 24.6;endothelial cell: 33.0;fibroblast: 34.7;oligodendrocyte precursor cell: 91.2;pericyte: 40.5;vascular associated smooth muscle cell: 58.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 69 "Fallopian tube cells: 6929.9" "Not detected" "Not detected" "HPA027802, CAB080462" Supported Supported Nucleoplasm Yes No "Cluster 32: Basophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 100: Stratified epithelial cells - Barrier functions" 98 Nucleoplasm "CAB080462: , HPA027802: " "unprognostic (1.44e-1)" "unprognostic (1.60e-1)" "unprognostic (8.16e-3)" "unprognostic (5.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.44e-2)" "unprognostic (3.66e-1)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (2.57e-2)" "validated prognostic favorable (3.18e-6)" "validated prognostic favorable (5.97e-4)" "unprognostic (2.46e-1)" "unprognostic (5.48e-2)" "unprognostic (4.00e-2)" "unprognostic (9.58e-3)" "unprognostic (2.02e-1)" "unprognostic (2.46e-2)" "unprognostic (4.68e-2)" "unprognostic (1.90e-2)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (1.60e-2)" "unprognostic (4.06e-2)" "unprognostic (3.82e-2)" "unprognostic (9.59e-2)" "unprognostic (2.35e-1)" "unprognostic (8.60e-2)" "unprognostic (7.20e-2)" "unprognostic (7.88e-3)" "unprognostic (2.16e-2)" CCND2 ENSG00000118971 "Cyclin D2" P30279 12 4269771-4305353 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 39.6;Megakaryocyte progenitors: 31.1;Megakaryocyte-Erythroid progenitors: 41.9;Müller glia: 47.7;Plasma cells: 53.2;Smooth muscle cells: 40.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 76.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 91.6;testis cancer: 82.4" "Heart muscle - Cardiomyocytes, Spleen - Mitotic cells (Spleen), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" "fallopian tube: 128675.1;lymphoid tissue: 145891.9" "HPA049138, HPA054196" Approved Enhanced Nucleoplasm Yes Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 36 Nucleoplasm "HPA049138: , HPA054196: " "unprognostic (3.15e-1)" "unprognostic (2.77e-2)" "potential prognostic favorable (7.56e-4)" "unprognostic (4.55e-2)" "unprognostic (4.39e-2)" "unprognostic (1.20e-1)" "unprognostic (8.68e-2)" "unprognostic (6.00e-2)" "unprognostic (1.01e-2)" "unprognostic (2.03e-2)" "unprognostic (8.88e-3)" "unprognostic (4.42e-2)" "unprognostic (1.21e-2)" "unprognostic (1.42e-2)" "unprognostic (1.12e-2)" "unprognostic (3.29e-1)" "unprognostic (3.15e-3)" "unprognostic (2.48e-2)" "unprognostic (2.33e-1)" "unprognostic (3.27e-1)" "potential prognostic favorable (9.80e-4)" "unprognostic (2.10e-1)" "unprognostic (1.15e-1)" "unprognostic (9.57e-3)" "unprognostic (1.88e-2)" "unprognostic (3.18e-1)" "unprognostic (1.29e-1)" "unprognostic (2.85e-1)" "unprognostic (6.51e-2)" "unprognostic (2.44e-1)" CCNE1 CCNE ENSG00000105173 "Cyclin E1" P24864 19 29811991-29824312 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.7;placenta: 29.0" "Cell type enriched" "Detected in many" 6 "Extravillous trophoblasts: 2489.6" "Cell type enriched" "Detected in many" 27 "Trophoblast cells: 2489.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Prostate - Smooth muscle cells, Spleen - Mitotic cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000308, CAB016682, HPA018169" Approved Enhanced Nucleoplasm,Cytosol Yes Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 54 Nucleoplasm Cytosol "CAB000308: , CAB016682: , HPA018169: " "unprognostic (7.01e-2)" "unprognostic (6.39e-3)" "unprognostic (1.88e-1)" "unprognostic (4.93e-2)" "unprognostic (1.35e-2)" "unprognostic (1.55e-2)" "unprognostic (8.46e-2)" "unprognostic (1.34e-1)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (2.39e-4)" "validated prognostic unfavorable (4.68e-5)" "validated prognostic unfavorable (1.84e-6)" "potential prognostic unfavorable (4.27e-4)" "validated prognostic unfavorable (1.34e-4)" "validated prognostic unfavorable (2.76e-4)" "potential prognostic unfavorable (8.63e-5)" "unprognostic (7.06e-3)" "unprognostic (2.16e-1)" "unprognostic (1.09e-1)" "unprognostic (2.13e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (4.51e-2)" "unprognostic (1.76e-1)" "unprognostic (6.87e-3)" "unprognostic (3.15e-1)" "unprognostic (8.56e-3)" "unprognostic (1.21e-1)" "unprognostic (2.77e-1)" "unprognostic (8.54e-2)" "unprognostic (2.36e-2)" CCNF "FBX1, FBXO1" ENSG00000162063 "Cyclin F" P41002 16 2429394-2458854 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Cyclin "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 14.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 44.7;Megakaryocyte progenitors: 30.1;Monocyte progenitors: 66.8" "Cell type enhanced" "Detected in many" "Erythrocytes: 44.7;Mononuclear phagocytes: 66.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Prostate - Prostate basal glandular cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA070495, HPA071600" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 633 Nucleoplasm "Centrosome, Cytosol" "HPA070495: , HPA071600: " "unprognostic (1.90e-2)" "unprognostic (2.09e-3)" "unprognostic (5.51e-2)" "unprognostic (8.90e-3)" "unprognostic (9.49e-3)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (8.59e-2)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (2.95e-9)" "validated prognostic unfavorable (1.71e-4)" "potential prognostic unfavorable (3.45e-4)" "validated prognostic unfavorable (9.57e-7)" "validated prognostic unfavorable (4.82e-5)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (1.14e-1)" "unprognostic (6.84e-3)" "unprognostic (1.44e-1)" "unprognostic (6.43e-2)" "unprognostic (1.38e-3)" "unprognostic (4.57e-3)" "unprognostic (3.87e-2)" "unprognostic (2.91e-2)" "unprognostic (3.83e-1)" "unprognostic (9.64e-2)" "unprognostic (9.84e-2)" "unprognostic (3.35e-2)" "unprognostic (2.48e-2)" "unprognostic (5.50e-3)" CCNG1 CCNG ENSG00000113328 "Cyclin G1" P51959 5 163437569-163446151 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Cyclin "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 235.9;Platelets: 566.7" "Cell type enhanced" "Detected in all" "Platelets: 566.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" CAB000350 Supported Supported Nucleoplasm NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 25: Non-specific - Ribosome" "Cluster 47: Platelets - Hemostasis" 22 Nucleoplasm "CAB000350: " "unprognostic (6.07e-3)" "unprognostic (1.57e-1)" "unprognostic (1.84e-1)" "unprognostic (3.37e-2)" "potential prognostic favorable (1.76e-4)" "unprognostic (3.18e-2)" "unprognostic (3.15e-1)" "unprognostic (8.33e-2)" "unprognostic (1.16e-1)" "unprognostic (7.00e-2)" "potential prognostic favorable (4.32e-13)" "unprognostic (1.61e-2)" "unprognostic (9.75e-2)" "unprognostic (1.78e-1)" "unprognostic (4.73e-2)" "unprognostic (5.49e-2)" "unprognostic (9.09e-2)" "unprognostic (3.50e-2)" "unprognostic (1.36e-1)" "unprognostic (2.34e-1)" "unprognostic (6.46e-3)" "unprognostic (1.92e-2)" "unprognostic (2.06e-2)" "unprognostic (1.34e-1)" "unprognostic (9.14e-3)" "unprognostic (1.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.10e-2)" "unprognostic (3.07e-1)" "unprognostic (1.57e-1)" "unprognostic (8.83e-2)" CCNI2 FLJ16793 ENSG00000205089 "Cyclin I family member 2" Q6ZMN8 5 132747426-132754403 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;intestine: 3.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 10.9;Colonocytes: 9.6;Epididymal clear cells: 44.9;Müller glia: 8.2;Oocytes: 69.1;Plasma cells: 13.1;Renal collecting duct intercalated cells: 20.9" "Cell type enhanced" "Detected in many" "Ductal cells: 20.9;Oocytes: 69.1;Reproductive supporting cells: 44.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.7" "Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate basal glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 160131 "Oocytes: 16013120.5" "Not detected" "Not detected" HPA056288 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 27: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 78: Plasma cells - Antibody production & ER-stress response" "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA056288: " "unprognostic (4.92e-2)" "unprognostic (1.66e-1)" "unprognostic (1.52e-2)" "unprognostic (2.03e-1)" "unprognostic (3.10e-3)" "unprognostic (1.58e-1)" "unprognostic (9.48e-2)" "unprognostic (1.08e-1)" "unprognostic (2.14e-1)" "unprognostic (2.87e-1)" "unprognostic (9.49e-3)" "unprognostic (8.97e-2)" "unprognostic (1.39e-2)" "unprognostic (5.90e-2)" "unprognostic (3.79e-1)" "unprognostic (2.92e-1)" CCNO "CCNU, FLJ22422, UDG2, UNG2" ENSG00000152669 "Cyclin O" P22674 5 55231152-55233608 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation" Cyclin "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.2;pancreas: 11.3;testis: 12.5" "Cell type enriched" "Detected in many" 6 "Respiratory deuterosomal cells: 995.2" "Cell type enriched" "Detected in many" 6 "Ciliated cells: 995.2" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 66.5;ependymal cell: 20.3" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 25.0" "Region enriched" "Detected in all" 5 "choroid plexus: 25.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 39 "Fallopian tube cells: 3922.1" "Not detected" "Not detected" "HPA050090, HPA076641" Uncertain Approved "Nucleoplasm,Nucleoli,Centriolar satellite" NA NA "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Nucleoplasm, Nucleoli" "Centriolar satellite" "HPA050090: , HPA076641: " "unprognostic (4.88e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (4.13e-2)" "unprognostic (1.90e-2)" "unprognostic (1.18e-1)" "unprognostic (7.34e-2)" "unprognostic (1.86e-1)" "unprognostic (1.22e-1)" "unprognostic (7.12e-2)" "unprognostic (2.62e-1)" "unprognostic (8.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.48e-2)" "unprognostic (2.22e-1)" "unprognostic (3.60e-2)" "unprognostic (1.27e-1)" "unprognostic (4.69e-2)" "unprognostic (5.30e-3)" "unprognostic (1.64e-1)" "potential prognostic favorable (5.52e-4)" "unprognostic (2.33e-1)" "unprognostic (2.45e-1)" "unprognostic (9.41e-3)" CCNQ "CycM, FAM58A" ENSG00000262919 "Cyclin Q" Q8N1B3 X 153587925-153600045 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 127.6;Syncytiotrophoblasts: 128.6" "Cell type enhanced" "Detected in many" "Trophoblast cells: 128.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 145 "Neurons: 16132.1;T-cells: 12787.4" "Not detected" "Not detected" "HPA050137, HPA059843" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Nucleoplasm, Cytosol" "HPA050137: , HPA059843: " "unprognostic (1.69e-3)" "unprognostic (4.39e-2)" "unprognostic (4.27e-1)" "unprognostic (3.56e-2)" "unprognostic (1.27e-1)" "unprognostic (3.56e-2)" "unprognostic (3.59e-3)" "unprognostic (2.35e-1)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (7.37e-2)" "potential prognostic unfavorable (8.47e-6)" "unprognostic (2.23e-1)" "unprognostic (3.42e-2)" "unprognostic (3.70e-2)" "unprognostic (2.41e-2)" "unprognostic (1.69e-1)" "unprognostic (6.15e-3)" "unprognostic (1.28e-2)" "unprognostic (3.18e-1)" "unprognostic (1.59e-2)" "unprognostic (1.52e-1)" "unprognostic (6.84e-2)" "unprognostic (7.70e-2)" "unprognostic (4.47e-2)" "unprognostic (9.69e-2)" CCNT1 "CCNT, CYCT1, HIVE1" ENSG00000129315 "Cyclin T1" O60563 12 48688458-48716998 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 171.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 727799.2;Granulosa cells: 243379.6;Neurons: 354154.7;T-cells: 552488.5" "Tissue enriched" "Detected in single" 7581 "lymphoid tissue: 758096.2" "HPA004892, CAB009016, HPA072012" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 54 Nucleoplasm Cytosol "CAB009016: , HPA004892: , HPA072012: " "unprognostic (1.15e-1)" "unprognostic (3.04e-3)" "unprognostic (9.59e-2)" "unprognostic (2.34e-2)" "unprognostic (1.86e-1)" "unprognostic (3.58e-2)" "unprognostic (5.08e-1)" "unprognostic (6.30e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-2)" "potential prognostic favorable (5.59e-5)" "unprognostic (2.75e-3)" "unprognostic (6.97e-2)" "unprognostic (1.75e-3)" "unprognostic (3.34e-1)" "unprognostic (8.64e-2)" "unprognostic (6.68e-2)" "unprognostic (1.99e-2)" "unprognostic (2.32e-1)" "unprognostic (4.54e-2)" "unprognostic (5.74e-2)" "unprognostic (6.91e-2)" "unprognostic (3.01e-3)" "unprognostic (8.42e-2)" "unprognostic (1.14e-1)" "unprognostic (1.01e-1)" "unprognostic (4.46e-2)" "unprognostic (2.60e-1)" "unprognostic (6.02e-2)" "unprognostic (3.42e-2)" "unprognostic (4.23e-2)" CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" "Differentiation, Neurogenesis, Spermatogenesis" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 189.2;Epicardial cells: 200.1;Esophageal apical cells: 170.9;Mesothelial cells: 265.2;Ocular epithelial cells: 181.8" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 265.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 8231667.9;Neutrophils: 7583904.1" "Tissue enhanced" "Detected in many" "pancreas: 1210100.5" HPA046825 Approved Supported "Plasma membrane" Yes No "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 20: Non-specific - Transcription regulation" 6 "Plasma membrane" "HPA046825: " "unprognostic (1.60e-1)" "unprognostic (2.87e-2)" "unprognostic (1.60e-1)" "unprognostic (9.31e-2)" "unprognostic (2.33e-2)" "unprognostic (2.77e-2)" "unprognostic (2.25e-1)" "unprognostic (2.74e-3)" "unprognostic (3.86e-1)" "unprognostic (1.74e-2)" "potential prognostic favorable (6.09e-7)" "unprognostic (9.30e-2)" "unprognostic (4.65e-2)" "unprognostic (1.49e-3)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (1.53e-1)" "unprognostic (6.12e-3)" "unprognostic (1.25e-2)" "unprognostic (3.65e-2)" "unprognostic (3.85e-2)" "unprognostic (3.32e-1)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (1.04e-1)" "unprognostic (4.90e-2)" "unprognostic (2.24e-1)" "unprognostic (2.72e-1)" "unprognostic (2.64e-2)" "unprognostic (2.49e-2)" "unprognostic (1.26e-1)" "unprognostic (2.88e-3)" CCPG1 "CPR8, KIAA1254" ENSG00000260916 "Cell cycle progression 1" Q9ULG6 15 55340032-55408510 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 258.9;Brain inhibitory neurons: 260.9;Choroid plexus epithelial cells: 113.3;Ependymal cells: 119.6;Loop of henle epithelial cells: 107.7;Neutrophil progenitors: 139.8;Neutrophils: 125.7;Other brain neurons: 220.8;Podocytes: 101.7;Renal collecting duct intercalated cells: 168.4;Renal collecting duct principal cells: 141.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 119.6;Ductal cells: 168.4;Neuronal cells: 260.9;Neutrophils: 139.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 280.3;neutrophil: 298.2" "Group enriched" "Detected in all" 7 "granulocytes: 298.2;monocytes: 84.8" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Endothelial cells, Stomach - Chief cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 1408991.4;Neutrophils: 3351614.9" "Tissue enriched" "Detected in some" "salivary gland: 646659.3" "HPA009432, HPA026861" Approved Approved "Endoplasmic reticulum,Golgi apparatus" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "Golgi apparatus" "Endoplasmic reticulum" "HPA009432: , HPA026861: " "unprognostic (7.88e-2)" "unprognostic (2.40e-2)" "unprognostic (2.49e-1)" "unprognostic (1.77e-2)" "unprognostic (7.22e-2)" "unprognostic (8.68e-3)" "unprognostic (3.30e-1)" "unprognostic (4.27e-3)" "unprognostic (3.82e-1)" "unprognostic (2.27e-3)" "potential prognostic favorable (1.35e-6)" "unprognostic (4.70e-3)" "unprognostic (2.65e-1)" "unprognostic (8.53e-2)" "unprognostic (9.20e-2)" "unprognostic (1.64e-2)" "unprognostic (3.43e-1)" "unprognostic (3.82e-2)" "unprognostic (2.30e-1)" "unprognostic (6.98e-2)" "unprognostic (6.94e-3)" "unprognostic (1.53e-2)" "unprognostic (4.35e-1)" "unprognostic (2.15e-1)" "unprognostic (8.26e-3)" "unprognostic (2.22e-1)" "unprognostic (2.55e-1)" "unprognostic (1.66e-2)" "unprognostic (1.77e-1)" "unprognostic (6.06e-3)" "unprognostic (3.02e-2)" CCR10 GPR2 ENSG00000184451 "C-C motif chemokine receptor 10" P46092 17 42678889-42683917 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 19.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 80.9;Epicardial cells: 61.4;Epididymal principal cells: 30.0;Pericytes: 36.9;Plasma cells: 106.5;Vascular smooth muscle cells: 16.8" "Group enriched" "Detected in many" 4 "Barrier epithelial cells: 61.4;Mural cells: 36.9;Myocytes: 80.9;Plasma cells: 106.5;Reproductive supporting cells: 30.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "plasmacytoid DC: 24.7;T-reg: 72.6" "Group enriched" "Detected in many" 8 "dendritic cells: 24.7;T-cells: 72.6" "Cancer enriched" "Detected in many" 4 "Myeloma: 42.2" "Adrenal gland - Adrenal medulla cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011684, HPA048007, HPA069188" Uncertain Approved "Endoplasmic reticulum" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 64: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 "Endoplasmic reticulum" "CAB011684: , HPA048007: , HPA069188: " "unprognostic (2.10e-2)" "unprognostic (3.94e-2)" "unprognostic (7.74e-2)" "unprognostic (2.82e-2)" "unprognostic (2.41e-2)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (3.70e-1)" "unprognostic (9.45e-3)" "unprognostic (3.24e-1)" "unprognostic (3.60e-1)" "unprognostic (1.83e-3)" "unprognostic (1.29e-1)" "unprognostic (2.16e-1)" "unprognostic (8.48e-2)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (2.58e-2)" CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353864-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.1" "Group enriched" "Detected in some" 4 "cDC: 22.8;Monocyte progenitors: 87.5;monocytes: 65.3;pDCs: 73.3;Plasma cells: 32.2" "Group enriched" "Detected in some" 8 "dendritic cells: 73.3;Mononuclear phagocytes: 87.5;Plasma cells: 32.2" "Cell type enriched" "Detected in single" 60 "leukocyte: 30.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 557.4" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Myeloma: 29.9" "Breast - Plasma cells, Minor Salivary Gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Myeloma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: , HPA063255: " "unprognostic (1.86e-1)" "unprognostic (1.05e-2)" "unprognostic (7.54e-2)" "unprognostic (2.92e-3)" "unprognostic (1.45e-1)" "unprognostic (2.66e-2)" "unprognostic (6.41e-3)" "unprognostic (1.23e-1)" "unprognostic (2.21e-2)" "unprognostic (8.66e-3)" "potential prognostic favorable (5.21e-6)" "unprognostic (1.77e-1)" "unprognostic (8.59e-2)" "unprognostic (1.19e-1)" "unprognostic (4.11e-1)" "unprognostic (1.97e-1)" "unprognostic (3.18e-1)" "unprognostic (7.17e-2)" "unprognostic (1.09e-2)" "unprognostic (4.69e-2)" "unprognostic (2.57e-2)" "unprognostic (1.22e-1)" CCRL2 "ACKR5, CKRX, CRAM-A, CRAM-B, HCR" ENSG00000121797 "C-C motif chemokine receptor like 2" O00421 3 46407166-46412997 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "cDC: 22.4;Enterocytes: 16.0;Goblet cells: 19.8;Hofbauer cells: 38.6;Kupffer cells: 18.4;Macrophages: 36.3;monocytes: 116.2;Neutrophils: 65.8;Paneth cells: 15.5;Platelets: 19.8" "Group enriched" "Detected in many" 4 "Mononuclear phagocytes: 116.2;Neutrophils: 65.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.4;endothelial cell: 7.7;vascular associated smooth muscle cell: 3.1" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 25.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 6143 "Alveolar cell types: 614276.4" "Tissue enriched" "Detected in some" "lung: 1687348.7" HPA043238 Approved Supported "Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Plasma membrane" "Primary cilium, Primary cilium tip" "HPA043238: " "unprognostic (8.87e-2)" "unprognostic (3.06e-1)" "unprognostic (3.77e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (4.57e-2)" "unprognostic (3.34e-1)" "unprognostic (1.56e-1)" "unprognostic (1.14e-1)" "unprognostic (1.02e-1)" "unprognostic (3.90e-3)" "unprognostic (1.09e-2)" "unprognostic (7.25e-2)" "unprognostic (8.77e-2)" "unprognostic (1.57e-1)" "unprognostic (2.92e-1)" "unprognostic (2.89e-2)" "unprognostic (5.84e-2)" "unprognostic (1.57e-1)" "unprognostic (3.40e-2)" "unprognostic (2.23e-1)" "unprognostic (9.76e-2)" "unprognostic (1.40e-2)" "unprognostic (5.83e-2)" "unprognostic (1.34e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.87e-4)" "unprognostic (7.30e-2)" "unprognostic (9.46e-2)" "unprognostic (4.12e-1)" "unprognostic (2.91e-1)" CCT2 Cctb ENSG00000166226 "Chaperonin containing TCP1 subunit 2" P78371 12 69585426-69601570 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1560.5;Late primary spermatocytes: 1325.4;Late spermatids: 576.2;Oocytes: 598.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1560.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA003197, HPA003198" Enhanced Supported "Cytosol,Connecting piece,Mid piece,Principal piece" NA NA 3400000 "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 326 Cytosol "Connecting piece, Mid piece, Principal piece" "HPA003197: , HPA003198: " "unprognostic (4.26e-3)" "unprognostic (1.04e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-1)" "unprognostic (9.90e-3)" "unprognostic (9.90e-3)" "unprognostic (6.64e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-3)" "unprognostic (4.03e-2)" "potential prognostic favorable (6.49e-6)" "unprognostic (3.26e-2)" "unprognostic (7.82e-2)" "validated prognostic unfavorable (4.42e-10)" "validated prognostic unfavorable (6.95e-6)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (3.14e-3)" "unprognostic (1.71e-1)" "unprognostic (2.60e-1)" "unprognostic (8.83e-2)" "unprognostic (2.69e-1)" "unprognostic (2.85e-2)" "unprognostic (1.96e-2)" "unprognostic (1.83e-3)" "unprognostic (2.45e-2)" "unprognostic (6.46e-2)" "unprognostic (2.11e-1)" "unprognostic (1.91e-1)" "unprognostic (2.15e-1)" "unprognostic (1.80e-1)" "unprognostic (2.23e-1)" CCT4 Cctd ENSG00000115484 "Chaperonin containing TCP1 subunit 4" P50991 2 61868085-61888671 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 573.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA029349 Supported Supported Nucleoplasm,Cytosol NA NA 2100000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 75: Non-specific - Chaperones and protein folding" 167 Cytosol Nucleoplasm "HPA029349: " "unprognostic (2.94e-2)" "unprognostic (1.81e-3)" "unprognostic (2.00e-2)" "unprognostic (2.41e-2)" "unprognostic (3.03e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (5.29e-2)" "unprognostic (4.00e-3)" "unprognostic (4.81e-3)" "potential prognostic favorable (1.33e-6)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (2.54e-4)" "validated prognostic unfavorable (9.30e-13)" "validated prognostic unfavorable (6.67e-6)" "potential prognostic unfavorable (5.57e-5)" "unprognostic (1.91e-3)" "unprognostic (6.64e-2)" "unprognostic (3.98e-1)" "unprognostic (2.42e-2)" "unprognostic (1.04e-2)" "unprognostic (2.19e-2)" "unprognostic (1.20e-2)" "unprognostic (6.90e-2)" "unprognostic (4.73e-2)" "unprognostic (1.59e-1)" "unprognostic (2.15e-1)" "unprognostic (2.45e-1)" "unprognostic (2.54e-1)" "unprognostic (3.63e-2)" "unprognostic (2.31e-1)" CCT5 KIAA0098 ENSG00000150753 "Chaperonin containing TCP1 subunit 5" P48643 5 10249929-10266389 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 421.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA002238, HPA005958, CAB006271" Enhanced Approved "Mid piece,Principal piece,Annulus" NA NA 1600000 "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 209 "Mid piece" "Principal piece, Annulus" "CAB006271: , HPA002238: , HPA005958: " "potential prognostic unfavorable (2.23e-4)" "unprognostic (1.52e-3)" "unprognostic (1.55e-2)" "unprognostic (2.42e-1)" "unprognostic (3.20e-1)" "unprognostic (3.14e-1)" "unprognostic (2.42e-1)" "unprognostic (3.37e-2)" "unprognostic (2.11e-2)" "unprognostic (4.88e-2)" "unprognostic (1.16e-3)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (3.29e-7)" "validated prognostic unfavorable (2.22e-10)" "validated prognostic unfavorable (6.74e-6)" "validated prognostic unfavorable (2.76e-4)" "validated prognostic unfavorable (1.92e-4)" "unprognostic (1.04e-1)" "unprognostic (2.22e-1)" "unprognostic (1.49e-2)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.45e-2)" "unprognostic (1.44e-3)" "unprognostic (9.83e-3)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (1.04e-1)" "unprognostic (4.64e-1)" "unprognostic (2.32e-1)" "unprognostic (2.01e-2)" CCT6A "CCT6, Cctz, HTR3, TCP20, TCPZ, TTCP20" ENSG00000146731 "Chaperonin containing TCP1 subunit 6A" P40227 7 56051685-56063989 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA042996, HPA045576, HPA049949" Supported Approved Cytosol NA NA 4200000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 212 Cytosol "HPA042996: , HPA045576: , HPA049949: " "potential prognostic unfavorable (5.17e-4)" "unprognostic (9.25e-3)" "unprognostic (1.14e-1)" "unprognostic (2.02e-2)" "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (2.11e-1)" "unprognostic (2.25e-1)" "unprognostic (5.60e-3)" "unprognostic (3.35e-3)" "potential prognostic favorable (1.52e-6)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (2.45e-4)" "validated prognostic unfavorable (1.55e-5)" "validated prognostic unfavorable (1.40e-8)" "potential prognostic unfavorable (1.61e-6)" "unprognostic (4.08e-3)" "unprognostic (1.54e-2)" "unprognostic (1.42e-1)" "unprognostic (1.13e-1)" "unprognostic (3.69e-1)" "unprognostic (5.16e-2)" "unprognostic (1.46e-2)" "unprognostic (9.45e-2)" "unprognostic (3.74e-2)" "unprognostic (2.06e-1)" "unprognostic (1.49e-1)" "unprognostic (7.95e-2)" "unprognostic (2.25e-1)" "unprognostic (5.27e-2)" "unprognostic (3.24e-2)" CCT6B "Cctz2, TSA303" ENSG00000132141 "Chaperonin containing TCP1 subunit 6B" Q92526 17 34927859-34981078 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "testis: 117.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 148.0;Early spermatids: 332.7;Epicardial cells: 134.2;Late primary spermatocytes: 1211.8;Late spermatids: 225.0" "Cell type enriched" "Detected in many" 9 "Spermatogenic cell types: 1211.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 138296.5;Oocytes: 139936.6;Proximal tubules: 203965.7" "Low tissue specificity" "Detected in many" "HPA042996, HPA045576, HPA049949" Uncertain Approved Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 57: Testis - Spermatogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 82 Cytosol "HPA042996: , HPA045576: , HPA049949: " "unprognostic (3.98e-2)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "unprognostic (3.51e-3)" "unprognostic (2.24e-1)" "unprognostic (1.08e-1)" "unprognostic (8.71e-2)" "unprognostic (1.64e-1)" "unprognostic (2.25e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (3.37e-8)" "unprognostic (6.33e-3)" "potential prognostic favorable (3.47e-4)" "unprognostic (1.21e-3)" "unprognostic (8.45e-3)" "unprognostic (3.06e-1)" "unprognostic (2.50e-1)" "unprognostic (2.98e-1)" "unprognostic (1.35e-1)" "unprognostic (2.04e-2)" "unprognostic (4.00e-2)" "unprognostic (8.84e-3)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (1.02e-2)" "unprognostic (4.05e-2)" "unprognostic (1.14e-1)" "unprognostic (5.40e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-3)" "unprognostic (4.69e-2)" CCT8 "C21orf112, Cctq, PRED71" ENSG00000156261 "Chaperonin containing TCP1 subunit 8" P50990 21 29055805-29073797 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 497.3" "Cell type enhanced" "Detected in all" "Oocytes: 497.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA018520, HPA021051, HPA029426" Enhanced Uncertain "Nucleoplasm,Cytosol,Connecting piece,Mid piece,Principal piece,End piece" NA No 3500000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 143 "Nucleoplasm, Connecting piece, End piece" "Cytosol, Mid piece, Principal piece" "HPA018520: , HPA021051: , HPA029426: " "unprognostic (2.60e-2)" "unprognostic (1.15e-3)" "unprognostic (9.16e-2)" "unprognostic (1.39e-2)" "unprognostic (2.66e-2)" "unprognostic (1.68e-2)" "unprognostic (2.05e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (5.65e-2)" "potential prognostic favorable (3.08e-4)" "unprognostic (1.74e-1)" "unprognostic (4.60e-3)" "validated prognostic unfavorable (3.02e-7)" "validated prognostic unfavorable (5.27e-5)" "validated prognostic unfavorable (1.00e-4)" "validated prognostic unfavorable (2.79e-4)" "unprognostic (1.57e-1)" "unprognostic (4.10e-1)" "unprognostic (3.21e-2)" "unprognostic (3.84e-1)" "unprognostic (1.45e-2)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (1.03e-2)" "unprognostic (1.96e-1)" "unprognostic (4.70e-1)" "unprognostic (2.43e-1)" "unprognostic (1.12e-1)" "unprognostic (3.59e-1)" "unprognostic (2.47e-1)" CCZ1 "C7orf28A, CCZ1A, CGI-43" ENSG00000122674 "CCZ1 homolog, vacuolar protein trafficking and biogenesis associated" P86791 7 5898725-5926550 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 7 Vesicles "HPA045114: , HPA050006: " "unprognostic (1.54e-2)" "unprognostic (1.05e-2)" "unprognostic (8.71e-3)" "unprognostic (3.58e-1)" "unprognostic (5.92e-2)" "unprognostic (3.51e-1)" "unprognostic (7.80e-2)" "unprognostic (5.56e-2)" "unprognostic (6.59e-2)" "unprognostic (2.15e-2)" "unprognostic (1.06e-2)" "unprognostic (1.89e-1)" "unprognostic (8.46e-3)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (1.56e-1)" "unprognostic (8.28e-3)" "unprognostic (4.78e-1)" "unprognostic (1.96e-1)" "unprognostic (5.47e-1)" "unprognostic (1.94e-3)" "unprognostic (9.34e-2)" "unprognostic (2.73e-2)" "unprognostic (1.57e-1)" "unprognostic (3.20e-3)" "unprognostic (1.82e-1)" "unprognostic (1.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.51e-1)" "unprognostic (1.16e-1)" "unprognostic (2.84e-2)" CCZ1B "C7orf28B, DKFZP586I1023, H_NH0577018.2, MGC19819" ENSG00000146574 "CCZ1 homolog B, vacuolar protein trafficking and biogenesis associated" P86790 7 6794134-6826770 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045114, HPA050006" Uncertain Enhanced Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 28 Vesicles "HPA045114: , HPA050006: " "unprognostic (7.78e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (3.70e-2)" "unprognostic (2.35e-1)" "unprognostic (1.75e-2)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (5.37e-5)" "unprognostic (1.50e-2)" "unprognostic (1.69e-1)" "unprognostic (6.20e-3)" "unprognostic (4.40e-2)" "unprognostic (9.40e-2)" "potential prognostic unfavorable (2.23e-5)" "unprognostic (7.15e-3)" "unprognostic (1.05e-1)" "unprognostic (7.65e-2)" "unprognostic (2.91e-1)" "unprognostic (1.45e-1)" "unprognostic (5.21e-2)" "unprognostic (6.53e-2)" "unprognostic (3.11e-3)" "unprognostic (2.43e-1)" "unprognostic (2.81e-1)" "unprognostic (9.00e-2)" "unprognostic (1.67e-1)" "unprognostic (3.73e-1)" "unprognostic (1.24e-1)" "unprognostic (3.37e-2)" "potential prognostic unfavorable (4.44e-4)" CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.8" "Cell type enhanced" "Detected in some" "B-cells: 47.7;Breast lactating cells: 57.6;cDC: 17.7;Epicardial cells: 22.7;Hofbauer cells: 150.3;Kupffer cells: 34.8;Macrophages: 26.6;Monocyte progenitors: 33.2;monocytes: 19.0;pDCs: 28.9;Plasma cells: 50.2" "Cell type enhanced" "Detected in some" "B-cells: 47.7;Mononuclear phagocytes: 150.3;Plasma cells: 50.2;Secretory cells: 57.6" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 17.2;leukocyte: 5.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.2;naive B-cell: 79.2" "Group enriched" "Detected in many" 25 "B-cells: 79.2;dendritic cells: 23.5;monocytes: 34.7" "Group enriched" "Detected in some" 4 "lymphoma: 19.2;Myeloma: 11.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Plasma cells, Colon - Macrophages, Heart muscle - Macrophages, Liver - Kupffer cells, Lung - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 12470 "B-cells: 1161161.5;Macrophages: 2263545.2;Neutrophils: 573807.0;T-cells: 989324.9" "Group enriched" "Detected in some" 10641 "bone marrow: 460262.8;intestine: 896475.5;lymphoid tissue: 1835461.3" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: " "unprognostic (1.08e-1)" "unprognostic (4.66e-2)" "unprognostic (1.85e-1)" "unprognostic (3.27e-2)" "unprognostic (3.61e-1)" "unprognostic (2.06e-2)" "unprognostic (1.15e-1)" "unprognostic (6.05e-3)" "unprognostic (1.29e-1)" "unprognostic (1.91e-1)" "unprognostic (3.30e-1)" "unprognostic (1.16e-2)" "unprognostic (4.80e-2)" "unprognostic (3.87e-2)" "unprognostic (9.02e-2)" "unprognostic (1.06e-1)" "unprognostic (3.29e-1)" "unprognostic (2.07e-1)" "unprognostic (5.95e-2)" "unprognostic (2.19e-2)" "unprognostic (1.21e-1)" "unprognostic (2.83e-2)" "unprognostic (3.22e-1)" CD207 "CLEC4K, Langerin" ENSG00000116031 "CD207 molecule" Q9UJ71 2 70830211-70835816 "CD markers, Disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 82.8" "Group enriched" "Detected in some" 4 "cDC: 6.8;Macrophages: 16.2;Retinal pigment epithelial cells: 4.3" "Group enriched" "Detected in some" 4 "dendritic cells: 6.8;Mononuclear phagocytes: 16.2;Pigment cells: 4.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 10.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.1" "Cancer enhanced" "Detected in some" "Bone cancer: 1.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 345179 "Keratinocytes: 34517868.1" "Group enriched" "Detected in some" 3148 "intestine: 568915.2;lymphoid tissue: 159069.9;skin: 216275.2" "CAB002222, HPA011216" Enhanced Uncertain Cytosol No NA "Cluster 37: Skin - Keratinization" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 82: Dendritic cells - Antigen presentation" 8 Cytosol "CAB002222: , HPA011216: " "unprognostic (3.24e-1)" "unprognostic (1.29e-2)" "unprognostic (1.97e-1)" "unprognostic (7.47e-2)" "unprognostic (2.17e-3)" "unprognostic (1.76e-1)" "potential prognostic favorable (9.63e-7)" "unprognostic (3.17e-3)" "unprognostic (2.39e-2)" "unprognostic (1.39e-3)" "unprognostic (2.60e-1)" "unprognostic (9.94e-2)" "unprognostic (2.63e-1)" "unprognostic (6.87e-2)" "unprognostic (9.69e-3)" "unprognostic (2.28e-1)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (4.94e-2)" "unprognostic (4.60e-1)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" CD24 CD24A ENSG00000272398 "CD24 molecule" P25063 6 106969831-106975627 "Cancer-related genes, CD markers, Disease related genes, Essential proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 1527.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 3586.9;Esophageal apical cells: 14637.2;Esophageal suprabasal cells: 3732.4;Pancreatic acinar cells: 2829.5;Parietal cells: 1942.9;Salivary duct cells: 1892.2" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 14637.2;Secretory cells: 3586.9;Suprabasal cells: 3732.4" "Cell type enriched" "Detected in many" 4 "ependymal cell: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 29 "eosinophil: 86.4;memory B-cell: 61.3;naive B-cell: 39.9" "Group enriched" "Detected in many" 240 "B-cells: 61.3;granulocytes: 86.4" "Cancer enhanced" "Detected in all" "breast cancer: 1239.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 159.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045879, CAB078471" Approved Approved Vesicles "Intracellular and membrane" "No annotated function" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 2 Vesicles "CAB078471: , HPA045879: " "unprognostic (1.35e-1)" "potential prognostic unfavorable (2.01e-7)" "unprognostic (3.01e-1)" "unprognostic (1.79e-3)" "unprognostic (7.39e-2)" "unprognostic (1.88e-3)" "unprognostic (2.76e-2)" "unprognostic (6.97e-2)" "unprognostic (1.65e-1)" "unprognostic (1.94e-2)" "unprognostic (9.58e-2)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (8.15e-5)" "unprognostic (2.69e-2)" "unprognostic (1.89e-1)" "unprognostic (4.25e-2)" "unprognostic (4.44e-1)" "unprognostic (7.10e-2)" "unprognostic (2.64e-1)" "unprognostic (2.25e-2)" "unprognostic (9.01e-2)" "potential prognostic favorable (8.25e-4)" "unprognostic (1.33e-1)" "unprognostic (2.36e-1)" "unprognostic (2.94e-1)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" "unprognostic (3.06e-1)" CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 219.6;breast: 146.3" "Cell type enhanced" "Detected in some" "Decidual stromal cells: 442.9;Endometrial stromal cells: 119.5;Fibroblasts: 145.8;Hepatic stellate cells: 38.7;Leydig cells: 84.5;Pericytes: 56.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 145.8;Leydig cells: 84.5;Stromal cells: 442.9" "Group enriched" "Detected in some" 6 "fibroblast: 42.7;pericyte: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.9" "Lineage enriched" "Detected in single" 145 "T-cells: 21.9" "Group enriched" "Detected in many" 6 "Bone cancer: 137.0;Neuroblastoma: 39.8;Sarcoma: 67.1" "Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Colon - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 1369131.4" "Tissue enhanced" "Detected in many" "skin: 27149388.5" HPA051856 Enhanced Approved "Plasma membrane" NA NA 12000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 "Plasma membrane" "HPA051856: " "unprognostic (2.03e-2)" "unprognostic (2.07e-1)" "unprognostic (6.90e-2)" "unprognostic (3.33e-2)" "unprognostic (2.04e-2)" "unprognostic (2.42e-1)" "unprognostic (5.25e-2)" "unprognostic (9.31e-3)" "unprognostic (3.84e-1)" "unprognostic (9.96e-2)" "unprognostic (5.53e-2)" "unprognostic (1.69e-3)" "unprognostic (1.08e-3)" "unprognostic (7.18e-3)" "unprognostic (3.33e-1)" "unprognostic (2.46e-2)" "unprognostic (6.04e-2)" "unprognostic (2.16e-2)" "unprognostic (1.86e-1)" "unprognostic (6.67e-2)" "unprognostic (1.77e-1)" "unprognostic (3.86e-2)" "unprognostic (1.74e-1)" "unprognostic (5.25e-2)" "unprognostic (5.28e-2)" "unprognostic (2.49e-1)" "unprognostic (8.49e-2)" "unprognostic (4.82e-2)" "unprognostic (5.92e-2)" "unprognostic (3.99e-2)" "unprognostic (1.59e-1)" CD2BP2 "LIN1, PPP1R59, Snu40, U5-52K" ENSG00000169217 "CD2 cytoplasmic tail binding protein 2" O95400 16 30350773-30355308 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 124.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 16148276.7" "Tissue enhanced" "Detected in many" "bone marrow: 78245129.6" "HPA041508, HPA061309" Enhanced Enhanced "Nuclear speckles,Cytosol" Yes No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 64: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 159 "Nuclear speckles" Cytosol "HPA041508: , HPA061309: " "unprognostic (1.36e-1)" "unprognostic (4.16e-2)" "unprognostic (1.51e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-1)" "unprognostic (1.59e-1)" "unprognostic (5.69e-2)" "potential prognostic favorable (3.07e-5)" "unprognostic (1.05e-1)" "unprognostic (4.57e-2)" "potential prognostic favorable (1.32e-6)" "unprognostic (9.43e-2)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (3.22e-5)" "unprognostic (3.81e-3)" "unprognostic (1.57e-1)" "unprognostic (2.60e-2)" "unprognostic (1.19e-1)" "unprognostic (9.83e-2)" "unprognostic (9.48e-2)" "unprognostic (1.41e-1)" "unprognostic (4.89e-2)" "unprognostic (7.32e-2)" "unprognostic (2.04e-1)" "unprognostic (5.32e-2)" "unprognostic (5.33e-2)" "unprognostic (6.89e-2)" "unprognostic (1.40e-1)" "unprognostic (8.96e-2)" "unprognostic (3.40e-1)" "unprognostic (4.62e-3)" CD300LG "CLM9, Trem4" ENSG00000161649 "CD300 molecule like family member g" Q6UXG3 17 43847148-43863639 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 123.7;breast: 107.6;placenta: 55.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 21.6;Epididymal principal cells: 8.8;Leydig cells: 12.8;Pericytes: 7.0;Peritubular myoid cells: 29.2;Sertoli cells: 17.8;Vascular endothelial cells: 68.1" "Cell type enhanced" "Detected in some" "Endothelial cells: 68.1;Myocytes: 21.6;Reproductive supporting cells: 17.8;Stromal cells: 29.2" "Cell type enhanced" "Detected in single" "endothelial cell: 1.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 770 "heart muscle: 77033.3" HPA004131 Approved Calyx NA NA 1700000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Calyx "HPA004131: " "unprognostic (8.68e-3)" "unprognostic (5.65e-2)" "unprognostic (1.83e-2)" "potential prognostic favorable (4.39e-7)" "unprognostic (1.76e-1)" "unprognostic (1.62e-1)" CD36 "FAT, GP3B, GP4, GPIV, SCARB3" ENSG00000135218 "CD36 molecule" P16671 7 80369575-80679277 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Lipid transport, Transport" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1439.4;breast: 534.4" "Cell type enhanced" "Detected in many" "Adipocytes: 2202.8;Breast lactating cells: 2901.1;Cardiomyocytes: 1067.0;Erythrocyte progenitors: 1495.3;Hofbauer cells: 3461.3;Lymphatic endothelial cells: 1005.7;Myonuclei: 2064.8;Pericytes: 773.1;Platelets: 531.9;Vascular endothelial cells: 611.6" "Cell type enhanced" "Detected in many" "Adipocytes: 2202.8;Erythrocytes: 1495.3;Mononuclear phagocytes: 3461.3;Myocytes: 2064.8;Secretory cells: 2901.1" "Group enriched" "Detected in all" 8 "deep-layer near-projecting: 201.4;ependymal cell: 542.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 87.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 965.2;intermediate monocyte: 271.3;myeloid DC: 507.9" "Group enriched" "Detected in all" 46 "dendritic cells: 507.9;monocytes: 965.2" "Cancer enhanced" "Detected in many" "thyroid cancer: 57.4" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Heart muscle - Cardiomyocytes, Liver - Sinusoid Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 13.2" "Group enriched" "Detected in many" "Capillaries: 63502668.5;Cardiomyocytes: 33865157.3;Skeletal myofibers: 35020805.1" "Tissue enhanced" "Detected in many" "heart muscle: 49674963.6;lymphoid tissue: 46393467.8" "HPA002018, CAB025866, HPA071026" Enhanced Enhanced "Golgi apparatus" NA NA 7200000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 46: Brainstem - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Golgi apparatus" "CAB025866: , HPA002018: , HPA071026: " "unprognostic (4.57e-2)" "unprognostic (2.13e-2)" "potential prognostic favorable (7.86e-4)" "unprognostic (7.58e-3)" "unprognostic (2.12e-1)" "unprognostic (1.72e-2)" "unprognostic (2.26e-1)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.23e-5)" "unprognostic (8.57e-3)" "unprognostic (2.91e-3)" "unprognostic (2.92e-1)" "unprognostic (2.07e-1)" "unprognostic (1.18e-2)" "unprognostic (1.92e-1)" "unprognostic (1.05e-2)" "unprognostic (3.66e-2)" "unprognostic (2.65e-1)" "unprognostic (2.77e-3)" "potential prognostic favorable (6.58e-4)" "unprognostic (4.28e-3)" "unprognostic (9.80e-2)" "unprognostic (2.19e-1)" "unprognostic (8.32e-2)" "unprognostic (6.56e-3)" "potential prognostic unfavorable (8.64e-4)" "unprognostic (8.82e-2)" "unprognostic (4.51e-2)" "unprognostic (2.15e-1)" CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 146.8;intestine: 112.2;lymphoid tissue: 233.1" "Cell type enhanced" "Detected in many" "B-cells: 991.1;cDC: 299.3;Hematopoietic stem cells: 199.9;Hofbauer cells: 451.9;Innate lymphoid cells: 186.7;Late spermatids: 351.2;Macrophages: 174.2;Mast cells: 396.0;monocytes: 301.1;Neutrophils: 356.7;NK-cells: 184.1;pDCs: 358.0;T-cells: 247.8" "Cell type enhanced" "Detected in many" "B-cells: 991.1;dendritic cells: 358.0;Mast cells: 396.0;Mononuclear phagocytes: 451.9;Neutrophils: 356.7;Spermatogenic cell types: 351.2" "Group enriched" "Detected in some" 34 "central nervous system macrophage: 120.8;leukocyte: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 77.0;lymphoma: 248.0" "Adrenal gland - Macrophages, Breast - T-cells, Prostate - T-cells, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "B-cells: 8618781.3;T-cells: 8443874.7" "Tissue enriched" "Detected in many" "lymphoid tissue: 6245081.7" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 8 "Golgi apparatus" "Plasma membrane" "CAB002492: , HPA032120: , HPA032121: " "unprognostic (1.12e-1)" "unprognostic (9.68e-3)" "unprognostic (1.49e-2)" "unprognostic (3.07e-2)" "unprognostic (3.44e-2)" "unprognostic (1.78e-1)" "unprognostic (1.59e-2)" "unprognostic (4.12e-1)" "unprognostic (1.89e-2)" "unprognostic (3.70e-1)" "unprognostic (2.72e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (8.87e-2)" "unprognostic (2.39e-2)" "unprognostic (5.78e-3)" "unprognostic (1.00e-1)" "unprognostic (4.04e-2)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (2.27e-1)" "unprognostic (6.54e-2)" "unprognostic (8.70e-2)" "unprognostic (1.54e-1)" "unprognostic (7.16e-2)" "unprognostic (7.67e-2)" "unprognostic (2.45e-3)" "unprognostic (9.56e-2)" "unprognostic (9.96e-3)" "unprognostic (2.33e-2)" "unprognostic (4.47e-2)" CD38 cADPR1 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853232 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 58.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 162.3;Astrocytes: 200.6;Hematopoietic stem cells: 196.5;Kupffer cells: 137.3;Megakaryocyte progenitors: 177.9;Megakaryocyte-Erythroid progenitors: 278.9;Monocyte progenitors: 135.3;Myonuclei: 93.6;NK-cells: 154.0;Plasma cells: 469.1;Respiratory ciliated cells: 168.1;Respiratory deuterosomal cells: 95.4;Thymocytes: 143.1" "Cell type enhanced" "Detected in many" "Megakaryocytes: 278.9;Plasma cells: 469.1" "Group enriched" "Detected in many" 4 "astrocyte: 240.4;leukocyte: 63.7;pericyte: 120.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 18.3" "Group enriched" "Detected in all" 5 "B-cells: 9.9;dendritic cells: 5.8;NK-cells: 18.3" "Group enriched" "Detected in some" 15 "Leukemia: 25.9;lymphoma: 43.3;Myeloma: 35.3" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 2455790.1;Macrophages: 4466468.2" "Tissue enhanced" "Detected in many" "cerebral cortex: 12143903.6;lymphoid tissue: 11902009.6" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 46: Brainstem - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" 3 "Plasma membrane" "CAB002493: , CAB025255: , HPA022132: , HPA052381: " "unprognostic (1.95e-1)" "unprognostic (1.10e-2)" "unprognostic (2.37e-1)" "unprognostic (1.11e-2)" "unprognostic (2.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.00e-1)" "unprognostic (2.40e-2)" "potential prognostic favorable (1.51e-4)" "unprognostic (1.18e-3)" "unprognostic (1.31e-1)" "unprognostic (6.14e-3)" "unprognostic (1.00e-1)" "unprognostic (8.73e-2)" "unprognostic (4.05e-2)" "unprognostic (5.33e-3)" "unprognostic (4.45e-1)" "unprognostic (2.37e-1)" "potential prognostic favorable (3.86e-5)" "unprognostic (1.97e-2)" "unprognostic (3.98e-1)" "unprognostic (3.16e-2)" "unprognostic (3.03e-1)" "unprognostic (6.26e-3)" "unprognostic (2.70e-2)" "unprognostic (2.34e-1)" "unprognostic (1.37e-1)" "unprognostic (5.92e-2)" "unprognostic (1.06e-1)" "unprognostic (2.28e-1)" CD3E "CD3-epsilon, CD3epsilon" ENSG00000198851 "CD3 epsilon subunit of T-cell receptor complex" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 596.2" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 58.7;NK-cells: 137.0;T-cells: 424.7;Thymocytes: 83.8" "Group enriched" "Detected in many" 4 "NK-cells: 137.0;T-cells: 424.7" "Cell type enriched" "Detected in some" 179 "leukocyte: 199.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 491.6;MAIT T-cell: 421.5;memory CD4 T-cell: 415.6;memory CD8 T-cell: 463.4;naive CD4 T-cell: 493.3;naive CD8 T-cell: 502.8;NK-cell: 203.3;T-reg: 427.4" "Group enriched" "Detected in all" 21 "NK-cells: 203.3;T-cells: 502.8" "Cancer enriched" "Detected in some" 8 "Leukemia: 125.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 23322027.7" "Group enriched" "Detected in some" 32288 "intestine: 1569034.7;lung: 2946293.9;lymphoid tissue: 5171076.7" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 38 "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: , CAB072863: , CAB072864: , HPA040957: , HPA043955: " "unprognostic (2.34e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (2.89e-2)" "potential prognostic favorable (2.43e-4)" "unprognostic (1.49e-1)" "unprognostic (1.11e-1)" "unprognostic (3.05e-3)" "unprognostic (8.41e-2)" "potential prognostic favorable (3.77e-4)" "unprognostic (2.18e-1)" "unprognostic (1.70e-1)" "unprognostic (2.67e-2)" "unprognostic (4.50e-2)" "unprognostic (1.28e-2)" "unprognostic (3.27e-2)" "unprognostic (2.30e-2)" "unprognostic (2.25e-1)" "unprognostic (5.00e-1)" "unprognostic (1.44e-1)" "unprognostic (8.79e-2)" "unprognostic (7.73e-2)" "unprognostic (1.22e-1)" "unprognostic (1.47e-1)" "unprognostic (1.82e-1)" "unprognostic (2.31e-2)" "unprognostic (2.26e-1)" "unprognostic (8.54e-3)" "unprognostic (1.20e-1)" "unprognostic (6.85e-2)" "unprognostic (1.29e-1)" "unprognostic (3.39e-2)" CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 469.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1692.5;cDC: 1408.4;Mast cells: 1993.4;monocytes: 2581.0;Neutrophils: 1651.0;Ocular epithelial cells: 1190.5;Pancreatic acinar cells: 2586.0;Pancreatic duct cells: 1846.1;Suprabasal keratinocytes: 1644.0" "Cell type enhanced" "Detected in many" "Acinar cells: 2586.0;Mononuclear phagocytes: 2581.0" "Cell type enhanced" "Detected in many" "astrocyte: 403.2;leukocyte: 474.2;vascular associated smooth muscle cell: 152.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 1400.7" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Keratinocytes: 94632156.4" "Tissue enhanced" "Detected in all" "salivary gland: 365465403.8" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" Receptor NA NA 260000000 200000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 27 "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: , HPA005785: " "unprognostic (1.93e-3)" "unprognostic (1.85e-1)" "unprognostic (3.84e-1)" "unprognostic (7.75e-2)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" "unprognostic (1.02e-3)" "unprognostic (1.90e-2)" "unprognostic (3.00e-2)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.76e-2)" "unprognostic (1.32e-3)" "unprognostic (3.08e-3)" "unprognostic (1.73e-1)" "unprognostic (5.04e-2)" "unprognostic (1.25e-2)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" "unprognostic (1.77e-3)" "unprognostic (1.44e-2)" "unprognostic (8.40e-2)" "unprognostic (1.58e-2)" "unprognostic (5.89e-3)" "unprognostic (8.97e-2)" "unprognostic (7.15e-2)" "unprognostic (1.25e-1)" "unprognostic (6.97e-2)" "unprognostic (8.74e-2)" CD74 "CLIP, DHLAG" ENSG00000019582 "CD74 molecule" P04233 5 150401637-150412969 "Cancer-related genes, CD markers, Disease related genes, Potential drug targets, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 4925.3" "Cell type enhanced" "Detected in many" "B-cells: 3923.1;cDC: 14449.7;Endometrial secretory cells: 1799.7;Enterocytes: 4957.0;Kupffer cells: 5170.7;Macrophages: 5932.6;monocytes: 2326.9;pDCs: 4090.1" "Group enriched" "Detected in all" 4 "B-cells: 3923.1;dendritic cells: 14449.7;Enterocytes: 4957.0;Mononuclear phagocytes: 5932.6" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 1596.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 11129.6;intermediate monocyte: 16174.8;memory B-cell: 27121.2;myeloid DC: 23965.9;naive B-cell: 28192.5;non-classical monocyte: 8146.1;plasmacytoid DC: 17015.9" "Group enriched" "Detected in all" 6 "B-cells: 28192.5;dendritic cells: 23965.9;monocytes: 16174.8" "Group enriched" "Detected in many" 7 "Leukemia: 998.7;lymphoma: 3214.7;Myeloma: 1807.4;skin cancer: 961.7" "Adipose visceral - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 26932702.4;B-cells: 24088293.3;Macrophages: 16890599.5;Pancreas epithelial cells: 20762691.4;T-cells: 18147602.8" "Tissue enhanced" "Detected in all" "lymphoid tissue: 91191182.8" "CAB002506, HPA010592, CAB079994" Enhanced Supported "Golgi apparatus" "Secreted to blood" Immunity NA NA 120000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 82: Dendritic cells - Antigen presentation" 19 "Golgi apparatus" "CAB002506: , CAB079994: , HPA010592: " "unprognostic (1.93e-3)" "potential prognostic favorable (9.48e-5)" "unprognostic (7.99e-2)" "unprognostic (1.92e-2)" "unprognostic (2.67e-1)" "unprognostic (3.10e-1)" "unprognostic (6.11e-2)" "unprognostic (1.82e-1)" "unprognostic (2.78e-2)" "unprognostic (2.35e-1)" "unprognostic (3.17e-1)" "unprognostic (4.14e-1)" "unprognostic (3.94e-2)" "unprognostic (3.54e-1)" "unprognostic (2.84e-2)" "unprognostic (1.12e-3)" "unprognostic (9.15e-2)" "unprognostic (9.54e-2)" "unprognostic (1.95e-1)" "unprognostic (2.52e-1)" "unprognostic (1.51e-2)" "unprognostic (2.89e-2)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "unprognostic (2.34e-2)" "unprognostic (2.56e-2)" "unprognostic (1.05e-1)" "unprognostic (5.36e-2)" "unprognostic (2.53e-1)" "unprognostic (2.47e-3)" CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 129.3" "Cell type enhanced" "Detected in some" "cDC: 53.2;Kupffer cells: 153.7;Macrophages: 99.3;Monocyte progenitors: 44.1;monocytes: 260.9;Neutrophil progenitors: 132.5;Neutrophils: 207.5;Vascular endothelial cells: 307.0" "Group enriched" "Detected in many" 4 "Endothelial cells: 307.0;Mononuclear phagocytes: 260.9;Neutrophils: 207.5" "Group enriched" "Detected in some" 21 "central nervous system macrophage: 10.9;endothelial cell: 34.4;leukocyte: 9.8;vascular associated smooth muscle cell: 15.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 65.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Cancer enhanced" "Detected in some" "Leukemia: 17.2;lymphoma: 6.8" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 3246098.3;Capillaries: 4002342.9;Neutrophils: 2156970.2" "Tissue enhanced" "Detected in many" "lung: 2600547.4" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 100000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 "Vesicles, Plasma membrane" "HPA009300: , HPA012368: " "unprognostic (7.45e-2)" "unprognostic (2.24e-1)" "unprognostic (5.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (4.14e-2)" "unprognostic (1.31e-1)" "unprognostic (1.54e-1)" "unprognostic (8.87e-2)" "unprognostic (4.81e-2)" "potential prognostic favorable (3.00e-6)" "unprognostic (1.42e-3)" "unprognostic (5.89e-3)" "unprognostic (8.97e-2)" "unprognostic (1.79e-1)" "unprognostic (7.47e-2)" "unprognostic (2.51e-2)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (2.62e-2)" "unprognostic (6.68e-3)" "unprognostic (2.25e-1)" "unprognostic (1.00e-1)" "unprognostic (1.09e-1)" "unprognostic (4.47e-2)" "unprognostic (8.62e-2)" "unprognostic (7.62e-2)" "unprognostic (1.30e-3)" "unprognostic (1.83e-1)" "unprognostic (1.68e-2)" "unprognostic (4.21e-1)" CDADC1 NYD-SP15 ENSG00000102543 "Cytidine and dCMP deaminase domain containing 1" Q9BWV3 13 49247925-49293485 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 232.3;Hematopoietic stem cells: 208.6;Neutrophil progenitors: 483.9;Neutrophils: 450.8" "Group enriched" "Detected in all" 4 "Neutrophils: 483.9;Spermatogenic cell types: 232.3;Stem cells: 208.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 9.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 9.9" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Glomeruli: 195941.4" "Not detected" "Not detected" "HPA047615, HPA058314" Uncertain Approved Nucleoplasm No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Nucleoplasm "HPA047615: , HPA058314: " "unprognostic (2.72e-1)" "unprognostic (1.07e-1)" "unprognostic (4.07e-2)" "unprognostic (5.42e-2)" "unprognostic (3.01e-1)" "unprognostic (1.82e-1)" "unprognostic (1.26e-1)" "unprognostic (1.52e-1)" "unprognostic (1.50e-1)" "unprognostic (2.28e-1)" "potential prognostic favorable (1.27e-9)" "unprognostic (1.46e-3)" "potential prognostic favorable (2.04e-4)" "unprognostic (9.82e-3)" "unprognostic (2.57e-1)" "potential prognostic favorable (5.02e-4)" "unprognostic (9.64e-2)" "unprognostic (1.18e-1)" "unprognostic (3.12e-2)" "unprognostic (1.61e-2)" "unprognostic (5.94e-3)" "unprognostic (1.87e-2)" "unprognostic (9.06e-3)" "unprognostic (1.30e-1)" "unprognostic (6.64e-2)" "unprognostic (1.54e-1)" "unprognostic (8.81e-3)" "unprognostic (1.11e-2)" "unprognostic (1.83e-1)" "unprognostic (3.49e-3)" "unprognostic (3.65e-2)" CDC14A "cdc14, Cdc14A1, Cdc14A2, DFNB105, DFNB32" ENSG00000079335 "Cell division cycle 14A" Q9UNH5 1 100345001-100520277 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Hearing" "Hydrolase, Protein phosphatase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 24.8" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 730.7;Podocytes: 1893.4;T-cells: 544.4" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 730.7;Renal nephron cells: 1893.4" "Cell type enhanced" "Detected in many" "astrocyte: 217.9;endothelial cell: 254.0;leukocyte: 300.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 18.9" "Kidney - Podocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6449 "Fallopian tube cells: 502479.3;Glomeruli: 787221.6" "Tissue enriched" "Detected in single" 8352 "fallopian tube: 835152.1" HPA023783 Approved Approved "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 "Nucleoplasm, Endoplasmic reticulum" Cytosol "HPA023783: " "unprognostic (2.68e-1)" "unprognostic (9.54e-2)" "unprognostic (4.80e-1)" "unprognostic (1.61e-1)" "unprognostic (4.57e-2)" "unprognostic (4.39e-3)" "unprognostic (2.78e-2)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (4.64e-3)" "validated prognostic favorable (1.36e-6)" "validated prognostic favorable (3.75e-4)" "unprognostic (3.53e-2)" "unprognostic (4.13e-1)" "unprognostic (4.25e-2)" "unprognostic (4.58e-2)" "unprognostic (8.32e-2)" "unprognostic (2.72e-2)" "unprognostic (3.79e-1)" "unprognostic (1.90e-2)" "unprognostic (1.56e-1)" "unprognostic (1.58e-2)" "unprognostic (2.75e-1)" "unprognostic (3.93e-3)" "unprognostic (2.57e-2)" "unprognostic (2.33e-1)" "unprognostic (9.33e-2)" "unprognostic (1.87e-1)" "unprognostic (5.86e-2)" "unprognostic (1.46e-1)" CDC20 "CDC20A, p55CDC" ENSG00000117399 "Cell division cycle 20" Q12834 1 43358981-43363203 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis, Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.8;lymphoid tissue: 49.0;testis: 46.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.1;Early spermatids: 120.5;Enteric transient amplifying cells: 103.3;Erythrocyte progenitors: 117.1;Esophageal basal cells: 131.2;Extravillous trophoblasts: 148.4;Gastric progenitor cells: 56.4;Hofbauer cells: 51.6;Late primary spermatocytes: 259.0;Megakaryocyte progenitors: 62.4;Migrating cytotrophoblasts: 119.5;Monocyte progenitors: 79.5" "Cell type enhanced" "Detected in many" "Basal cells: 131.2;Erythrocytes: 117.1;Proliferating cells: 103.3;Spermatogenic cell types: 259.0;Trophoblast cells: 148.4" "Cell type enhanced" "Detected in single" "oligodendrocyte: 2.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "memory B-cell: 4.2;memory CD4 T-cell: 3.2;memory CD8 T-cell: 3.5;NK-cell: 9.6;T-reg: 11.6" "Group enriched" "Detected in many" 9 "B-cells: 4.2;NK-cells: 9.6;T-cells: 11.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 1744 "Granulosa cells: 174394.7" "Not detected" "Not detected" "CAB004525, HPA045842, HPA055288" Enhanced Approved Nucleoplasm,Cytosol Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 123 "Nucleoplasm, Cytosol" "CAB004525: , HPA045842: , HPA055288: " "unprognostic (1.23e-3)" "unprognostic (9.83e-3)" "unprognostic (1.12e-1)" "unprognostic (2.93e-2)" "unprognostic (5.30e-3)" "unprognostic (7.61e-2)" "unprognostic (2.61e-1)" "unprognostic (8.32e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (3.74e-4)" "validated prognostic unfavorable (7.80e-14)" "validated prognostic unfavorable (2.16e-6)" "potential prognostic unfavorable (7.85e-11)" "validated prognostic unfavorable (1.66e-8)" "validated prognostic unfavorable (9.25e-9)" "validated prognostic unfavorable (2.76e-4)" "validated prognostic unfavorable (5.85e-5)" "unprognostic (2.32e-1)" "unprognostic (2.54e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (8.10e-4)" "potential prognostic unfavorable (7.75e-5)" "unprognostic (1.01e-1)" "unprognostic (1.24e-1)" "unprognostic (7.63e-2)" "unprognostic (2.38e-1)" "unprognostic (3.21e-3)" "unprognostic (3.77e-2)" "unprognostic (3.51e-1)" "unprognostic (1.36e-1)" "unprognostic (7.95e-2)" CDC25A ENSG00000164045 "Cell division cycle 25A" P30304 3 48157146-48188417 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 14.4;lymphoid tissue: 8.2;testis: 12.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 20.8;Early primary spermatocytes: 16.4;Early spermatids: 19.5;Erythrocyte progenitors: 32.1;Late primary spermatocytes: 14.5;Late spermatids: 48.1;Megakaryocyte progenitors: 20.4;Monocyte progenitors: 16.0;Neutrophil progenitors: 11.2;Oocytes: 13.8;Undifferentiated spermatogonia: 12.0" "Cell type enhanced" "Detected in many" "Erythrocytes: 32.1;Megakaryocytes: 20.4;Spermatogenic cell types: 48.1" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 31.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 166 "Neurons: 16577.7" "Not detected" "Not detected" "HPA005855, HPA008803" Approved "Nucleoplasm,Golgi apparatus" NA Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 44 Nucleoplasm "Golgi apparatus" "HPA005855: , HPA008803: " "unprognostic (3.43e-2)" "unprognostic (1.21e-1)" "unprognostic (2.31e-1)" "unprognostic (8.30e-2)" "unprognostic (4.14e-2)" "unprognostic (5.32e-1)" "unprognostic (2.97e-1)" "unprognostic (2.18e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.57e-5)" "unprognostic (3.48e-2)" "validated prognostic unfavorable (4.35e-7)" "validated prognostic unfavorable (6.53e-7)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (8.13e-3)" "unprognostic (9.67e-3)" "unprognostic (2.42e-2)" "unprognostic (9.18e-2)" "unprognostic (1.64e-1)" "unprognostic (6.47e-2)" "unprognostic (1.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (2.25e-1)" "unprognostic (1.56e-1)" CDC25B ENSG00000101224 "Cell division cycle 25B" P30305 20 3786772-3806121 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 60.6;Brain inhibitory neurons: 63.4;Corticotrophs: 62.1;Retinal ganglion cells: 65.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 7.2;NK-cells: 18.1;T-cells: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 238 "salivary gland: 23753.1" "HPA038892, HPA038893, HPA075215" Enhanced Uncertain "Vesicles,Mitotic spindle" Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 34 Vesicles "Mitotic spindle" "HPA038892: , HPA038893: , HPA075215: " "unprognostic (4.43e-2)" "unprognostic (4.64e-2)" "unprognostic (2.25e-2)" "unprognostic (1.03e-1)" "unprognostic (9.74e-2)" "unprognostic (1.36e-2)" "unprognostic (1.46e-1)" "unprognostic (9.25e-3)" "unprognostic (1.64e-1)" "unprognostic (1.74e-3)" "potential prognostic unfavorable (3.01e-6)" "unprognostic (4.12e-3)" "unprognostic (6.94e-2)" "validated prognostic unfavorable (1.42e-4)" "validated prognostic unfavorable (4.00e-4)" "unprognostic (3.92e-2)" "unprognostic (7.36e-2)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (5.41e-2)" "unprognostic (2.89e-1)" "unprognostic (1.62e-2)" "unprognostic (9.75e-2)" "unprognostic (2.49e-2)" "unprognostic (6.67e-2)" "unprognostic (1.80e-1)" "unprognostic (6.85e-2)" "unprognostic (7.07e-2)" "unprognostic (7.47e-2)" "unprognostic (3.27e-1)" "unprognostic (3.03e-1)" "unprognostic (9.01e-2)" CDC25C "CDC25, PPP1R60" ENSG00000158402 "Cell division cycle 25C" P30307 5 138285269-138338355 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.4;lymphoid tissue: 8.3;testis: 16.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 72.2;Early spermatids: 91.4;Enteric transient amplifying cells: 37.3;Erythrocyte progenitors: 45.8;Late primary spermatocytes: 92.1;Late spermatids: 63.1;Megakaryocyte progenitors: 34.3;Monocyte progenitors: 58.8;Neutrophil progenitors: 35.7;Oocytes: 50.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 45.8;Mononuclear phagocytes: 58.8;Oocytes: 50.7;Spermatogenic cell types: 92.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1524 "Granulosa cells: 152391.3" "Not detected" "Not detected" "CAB003800, HPA066991" Approved Supported "Nuclear speckles" No Yes "Cluster 39: Testis - Nuclear processes" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 55 "Nuclear speckles" "CAB003800: , HPA066991: " "unprognostic (2.46e-2)" "unprognostic (4.14e-2)" "unprognostic (3.47e-1)" "unprognostic (4.24e-3)" "unprognostic (3.25e-3)" "unprognostic (9.47e-2)" "unprognostic (9.35e-2)" "unprognostic (3.82e-2)" "unprognostic (1.09e-1)" "validated prognostic unfavorable (2.57e-8)" "validated prognostic unfavorable (5.09e-6)" "validated prognostic unfavorable (2.26e-7)" "validated prognostic unfavorable (6.28e-8)" "potential prognostic unfavorable (2.38e-5)" "unprognostic (1.91e-3)" "unprognostic (2.64e-3)" "unprognostic (7.14e-2)" "unprognostic (1.42e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.95e-4)" "unprognostic (2.88e-3)" "unprognostic (9.00e-2)" "unprognostic (4.01e-2)" "unprognostic (8.14e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-2)" "unprognostic (1.93e-1)" "unprognostic (8.08e-3)" CDC34 "E2-CDC34, UBC3, UBE2R1" ENSG00000099804 "Cell division cycle 34, ubiqiutin conjugating enzyme" P49427 19 531760-542092 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocytes: 109.2;Late spermatids: 384.6" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 384.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 9435136.4;lymphoid tissue: 8666789.6" "HPA002382, CAB005109, CAB047311, HPA074334" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 35 "Nucleoplasm, Nuclear speckles" Cytosol "CAB005109: , CAB047311: , HPA002382: , HPA074334: " "unprognostic (3.09e-1)" "unprognostic (4.16e-2)" "unprognostic (2.54e-2)" "unprognostic (2.22e-1)" "unprognostic (5.41e-2)" "unprognostic (3.80e-1)" "unprognostic (2.93e-1)" "unprognostic (1.72e-1)" "unprognostic (2.27e-2)" "unprognostic (3.41e-2)" "unprognostic (6.77e-3)" "unprognostic (6.83e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (5.03e-2)" "unprognostic (5.99e-3)" "unprognostic (7.03e-2)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (1.32e-1)" "unprognostic (6.33e-2)" "unprognostic (7.85e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (2.87e-1)" "unprognostic (2.89e-1)" "unprognostic (1.12e-2)" "unprognostic (5.15e-2)" "unprognostic (1.50e-2)" "unprognostic (1.47e-1)" CDC42 "CDC42Hs, G25K" ENSG00000070831 "Cell division cycle 42" P60953 1 22052627-22101360 "Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 90.8;Microglia: 123.1;Oligodendrocytes: 97.3;Other brain neurons: 129.6;Papillary tip epithelial cells: 153.4;Renal collecting duct intercalated cells: 91.4;Renal collecting duct principal cells: 107.3" "Cell type enhanced" "Detected in many" "Glial cells: 123.1;Neuronal cells: 129.6;Renal nephron cells: 153.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004360, HPA069590" Approved Supported "Microtubules,Cytokinetic bridge" Yes No 2900000 "Cluster 28: Neutrophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 98: Neurons - Neurotransmission & signaling" 239 Microtubules "Cytokinetic bridge" "CAB004360: , HPA069590: " "potential prognostic unfavorable (9.26e-4)" "unprognostic (7.91e-2)" "unprognostic (3.60e-2)" "unprognostic (1.05e-2)" "potential prognostic favorable (6.82e-4)" "unprognostic (3.44e-1)" "unprognostic (9.37e-2)" "unprognostic (3.17e-1)" "unprognostic (6.27e-2)" "unprognostic (4.52e-2)" "potential prognostic favorable (1.93e-8)" "unprognostic (1.66e-2)" "unprognostic (3.84e-1)" "validated prognostic unfavorable (1.23e-5)" "validated prognostic unfavorable (3.25e-4)" "unprognostic (1.28e-1)" "unprognostic (1.41e-1)" "unprognostic (1.12e-1)" "unprognostic (2.27e-1)" "unprognostic (2.12e-1)" "unprognostic (2.31e-2)" "unprognostic (9.55e-3)" "unprognostic (9.15e-2)" "unprognostic (3.85e-2)" "unprognostic (2.80e-1)" "unprognostic (6.31e-2)" "unprognostic (4.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.10e-1)" "unprognostic (1.74e-2)" "unprognostic (9.71e-2)" CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 143.2;Cholangiocytes: 147.6;Esophageal apical cells: 379.4;Esophageal basal cells: 129.7;Esophageal suprabasal cells: 126.6;Extravillous trophoblasts: 157.1;Fallopian secretory cells: 173.8;Gastric chief cells: 132.1;Mucous neck cells: 157.9;Pancreatic duct cells: 195.7;Parietal cells: 139.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 379.4" "Cell type enhanced" "Detected in many" "oligodendrocyte: 72.2;pericyte: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 3124102.9;Glomeruli: 2868051.2" "Low tissue specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 20 "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: , HPA076536: " "unprognostic (1.84e-2)" "unprognostic (1.18e-1)" "unprognostic (2.93e-1)" "unprognostic (2.50e-2)" "unprognostic (2.51e-1)" "unprognostic (4.29e-1)" "unprognostic (1.77e-1)" "unprognostic (2.56e-1)" "unprognostic (2.47e-1)" "unprognostic (1.06e-1)" "unprognostic (9.23e-2)" "unprognostic (1.74e-2)" "unprognostic (1.31e-1)" "unprognostic (4.14e-2)" "unprognostic (3.54e-2)" "unprognostic (6.89e-2)" "unprognostic (1.02e-2)" "unprognostic (2.65e-2)" "unprognostic (1.91e-1)" "unprognostic (1.19e-1)" "unprognostic (1.20e-1)" "unprognostic (2.52e-2)" "unprognostic (6.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.78e-1)" "unprognostic (4.62e-2)" "unprognostic (3.87e-2)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (5.75e-2)" "unprognostic (1.19e-1)" CDC42EP5 "Borg3, CEP5" ENSG00000167617 "CDC42 effector protein 5" Q6NZY7 19 54465026-54473296 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 79.6" "Cell type enhanced" "Detected in some" "Colonocytes: 5.2;Endometrial secretory cells: 12.0;Enterocytes: 5.5;Goblet cells: 8.2;Lymphatic endothelial cells: 5.2;Papillary tip epithelial cells: 34.5;Prostatic club cells: 19.1;Prostatic glandular cells: 5.2;Prostatic hillock cells: 12.4;Renal collecting duct principal cells: 7.3;Urothelial cells: 10.1" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 12.4;Glandular cells: 19.1;Renal nephron cells: 34.5;Secretory cells: 12.0" "Cell type enhanced" "Detected in many" "endothelial cell: 20.2;fibroblast: 32.6;pericyte: 13.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Fibroblasts, Prostate - Prostate glandular cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 259056.4;Smooth muscle cells: 190625.7" "Tissue enhanced" "Detected in many" "ovary: 3279815.6" HPA043449 Approved Approved "Nucleoplasm,Primary cilium,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 105: Non-specific - Mixed function" 1 "Primary cilium" "Nucleoplasm, Cytosol" "HPA043449: " "unprognostic (1.69e-1)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (3.65e-2)" "unprognostic (7.85e-2)" "unprognostic (3.77e-3)" "unprognostic (8.22e-2)" "unprognostic (5.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.62e-2)" "unprognostic (3.65e-2)" "unprognostic (5.69e-2)" "unprognostic (6.81e-2)" "unprognostic (2.39e-2)" "unprognostic (1.42e-1)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (1.99e-1)" "unprognostic (6.98e-2)" "unprognostic (1.80e-1)" "unprognostic (1.31e-1)" "unprognostic (4.13e-2)" "unprognostic (1.14e-1)" "unprognostic (1.84e-2)" "unprognostic (2.25e-1)" "unprognostic (2.49e-2)" "unprognostic (3.13e-2)" CDC6 CDC18L ENSG00000094804 "Cell division cycle 6" Q99741 17 40287879-40304657 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 25.7;lymphoid tissue: 16.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 27.3;Differentiating spermatogonia: 30.2;Early primary spermatocytes: 120.0;Erythrocyte progenitors: 69.4;Esophageal basal cells: 24.6;Extravillous trophoblasts: 39.5;Gastric progenitor cells: 25.6;Megakaryocyte progenitors: 39.2;Migrating cytotrophoblasts: 36.0;Monocyte progenitors: 25.4;Oocytes: 59.9" "Cell type enhanced" "Detected in many" "Erythrocytes: 69.4;Oocytes: 59.9;Spermatogenic cell types: 120.0" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 5.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 6 "dendritic cells: 3.6;NK-cells: 1.5;T-cells: 2.4" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050114, HPA065070" Approved Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 29 "Nucleoplasm, Cytosol" "Cytokinetic bridge, Mitotic spindle" "HPA050114: , HPA065070: " "unprognostic (3.46e-2)" "unprognostic (2.31e-1)" "unprognostic (2.34e-2)" "unprognostic (1.32e-1)" "unprognostic (9.50e-2)" "unprognostic (5.76e-3)" "unprognostic (2.13e-1)" "unprognostic (1.50e-3)" "unprognostic (5.34e-2)" "unprognostic (1.81e-3)" "validated prognostic unfavorable (6.41e-4)" "validated prognostic unfavorable (3.11e-4)" "potential prognostic unfavorable (2.73e-9)" "validated prognostic unfavorable (4.45e-6)" "validated prognostic unfavorable (6.25e-9)" "potential prognostic unfavorable (6.58e-5)" "unprognostic (5.42e-3)" "unprognostic (5.84e-2)" "unprognostic (4.95e-2)" "unprognostic (8.63e-2)" "unprognostic (3.14e-2)" "validated prognostic unfavorable (5.64e-4)" "validated prognostic unfavorable (2.90e-4)" "unprognostic (5.14e-2)" "unprognostic (2.19e-3)" "unprognostic (3.29e-3)" "unprognostic (5.42e-3)" "unprognostic (6.04e-3)" "unprognostic (2.56e-1)" "unprognostic (6.25e-2)" "unprognostic (1.58e-2)" CDC7 "CDC7L1, HsCdc7, Hsk1, huCdc7" ENSG00000097046 "Cell division cycle 7" O00311 1 91500851-91525764 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.8" "Cell type enriched" "Detected in many" 4 "Breast lactating cells: 298.9" "Cell type enriched" "Detected in many" 4 "Secretory cells: 298.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 7 "Gallbladder cancer: 199.8" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5079 "Granulosa cells: 507874.1" "Not detected" "Not detected" "CAB002669, HPA035831" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 2: Neurons - Nucleosome" "Cluster 37: Non-specific - mRNA processing" "Cluster 4: Breast lactating luminal cells - Lactation" 55 Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "CAB002669: , HPA035831: " "unprognostic (1.02e-1)" "unprognostic (1.07e-1)" "unprognostic (5.79e-3)" "unprognostic (3.87e-1)" "unprognostic (9.50e-2)" "unprognostic (1.64e-1)" "unprognostic (2.05e-1)" "unprognostic (7.05e-3)" "unprognostic (5.37e-3)" "potential prognostic unfavorable (1.00e-4)" "potential prognostic unfavorable (3.45e-6)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (3.09e-6)" "unprognostic (4.20e-3)" "unprognostic (4.27e-3)" "unprognostic (6.50e-3)" "unprognostic (4.97e-3)" "potential prognostic favorable (4.14e-4)" "unprognostic (1.61e-2)" "unprognostic (1.54e-2)" "unprognostic (1.12e-1)" "unprognostic (1.69e-2)" "unprognostic (3.11e-2)" "unprognostic (7.12e-3)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" "unprognostic (6.34e-2)" "unprognostic (1.80e-1)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" CDC73 "C1orf28, FIHP, HRPT1, HRPT2, parafibromin" ENSG00000134371 "Cell division cycle 73" Q6P1J9 1 193121983-193254815 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 15296829.4" "Tissue enhanced" "Detected in many" "intestine: 6972603.2;lymphoid tissue: 5913121.3" "HPA002326, CAB016359, HPA069324" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 105 Nucleoplasm Cytosol "CAB016359: , HPA002326: , HPA069324: " "unprognostic (2.13e-1)" "unprognostic (1.85e-2)" "unprognostic (3.50e-2)" "unprognostic (2.34e-1)" "unprognostic (2.53e-1)" "unprognostic (1.30e-1)" "unprognostic (7.06e-3)" "unprognostic (1.52e-1)" "unprognostic (5.71e-2)" "unprognostic (3.68e-3)" "potential prognostic favorable (2.69e-6)" "unprognostic (4.97e-2)" "unprognostic (1.26e-3)" "unprognostic (3.85e-3)" "unprognostic (8.97e-2)" "unprognostic (1.10e-2)" "unprognostic (4.59e-1)" "unprognostic (1.12e-1)" "unprognostic (4.48e-2)" "unprognostic (1.01e-1)" "unprognostic (1.26e-3)" "unprognostic (1.42e-2)" "unprognostic (7.60e-3)" "unprognostic (1.36e-1)" "unprognostic (2.07e-1)" "unprognostic (8.77e-2)" "unprognostic (2.92e-1)" "unprognostic (9.61e-2)" "unprognostic (2.47e-1)" "unprognostic (8.47e-3)" "unprognostic (3.63e-1)" CDCA2 "PPP1R81, Repo-Man" ENSG00000184661 "Cell division cycle associated 2" Q69YH5 8 25459199-25507911 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 6.1;lymphoid tissue: 10.6;testis: 18.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.3;Differentiating spermatogonia: 52.2;Early primary spermatocytes: 53.5;Early spermatids: 39.2;Erythrocyte progenitors: 64.4;Extravillous trophoblasts: 29.8;Late primary spermatocytes: 108.7;Late spermatids: 32.5;Megakaryocyte progenitors: 40.2;Monocyte progenitors: 73.7;Neutrophil progenitors: 31.3;Undifferentiated spermatogonia: 40.4" "Cell type enhanced" "Detected in many" "Erythrocytes: 64.4;Mononuclear phagocytes: 73.7;Spermatogenic cell types: 108.7" "Cell type enhanced" "Detected in some" "lower rhombic lip: 3.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 670 "Granulosa cells: 67045.9" "Tissue enriched" "Detected in single" 57 "bone marrow: 5719.8" "HPA026293, HPA030049" Enhanced Supported Nucleoplasm,Cytosol Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 13 Nucleoplasm Cytosol "HPA026293: , HPA030049: " "unprognostic (1.07e-3)" "unprognostic (2.77e-1)" "unprognostic (1.59e-1)" "unprognostic (7.25e-3)" "unprognostic (3.90e-3)" "unprognostic (1.38e-2)" "unprognostic (9.81e-2)" "unprognostic (3.96e-2)" "unprognostic (6.26e-3)" "unprognostic (2.68e-2)" "potential prognostic unfavorable (1.19e-5)" "potential prognostic unfavorable (9.85e-6)" "unprognostic (1.56e-2)" "unprognostic (3.23e-2)" "unprognostic (2.63e-1)" "unprognostic (3.51e-1)" "unprognostic (9.93e-2)" "potential prognostic unfavorable (8.97e-4)" "unprognostic (1.42e-3)" "unprognostic (3.93e-2)" "unprognostic (1.54e-1)" "unprognostic (2.47e-2)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" CDCA5 ENSG00000146670 "Cell division cycle associated 5" Q96FF9 11 65066300-65084164 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 50.4;lymphoid tissue: 25.7;testis: 37.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 48.2;Early primary spermatocytes: 36.3;Early spermatids: 49.1;Erythrocyte progenitors: 47.5;Esophageal basal cells: 31.1;Extravillous trophoblasts: 46.9;Late primary spermatocytes: 103.7;Late spermatids: 208.1;Megakaryocyte progenitors: 38.3;Migrating cytotrophoblasts: 45.4;Monocyte progenitors: 59.4;Neutrophil progenitors: 28.2;Oocytes: 32.2" "Cell type enhanced" "Detected in many" "Erythrocytes: 47.5;Mononuclear phagocytes: 59.4;Spermatogenic cell types: 208.1;Trophoblast cells: 46.9" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "NK-cell: 2.8;T-reg: 2.0" "Group enriched" "Detected in many" 5 "NK-cells: 2.8;T-cells: 2.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2042 "Granulosa cells: 204236.8" "Tissue enriched" "Detected in single" 143 "bone marrow: 14323.7" "HPA023691, HPA076007" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 32 Nucleoplasm "HPA023691: , HPA076007: " "unprognostic (3.18e-2)" "unprognostic (2.32e-2)" "unprognostic (8.37e-2)" "unprognostic (1.80e-1)" "unprognostic (3.79e-1)" "unprognostic (2.71e-1)" "unprognostic (1.84e-1)" "unprognostic (7.87e-3)" "unprognostic (2.94e-1)" "potential prognostic unfavorable (3.44e-4)" "validated prognostic unfavorable (1.23e-7)" "validated prognostic unfavorable (4.34e-5)" "potential prognostic unfavorable (1.44e-7)" "validated prognostic unfavorable (5.12e-6)" "validated prognostic unfavorable (5.37e-9)" "validated prognostic unfavorable (3.12e-5)" "validated prognostic unfavorable (5.36e-5)" "unprognostic (3.20e-1)" "unprognostic (1.48e-2)" "unprognostic (1.33e-1)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (6.41e-6)" "unprognostic (3.56e-3)" "unprognostic (1.72e-2)" "unprognostic (6.61e-2)" "unprognostic (1.99e-2)" "unprognostic (5.59e-3)" "unprognostic (3.41e-3)" "unprognostic (2.56e-1)" "unprognostic (7.72e-2)" "unprognostic (5.52e-2)" CDCA7 "FLJ14736, JPO1" ENSG00000144354 "Cell division cycle associated 7" Q9BWT1 2 173354820-173368997 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 26.5;lymphoid tissue: 41.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 56.6;Decidual stromal cells: 63.0;Enteric stem cells: 206.7;Enteric transient amplifying cells: 109.7;Esophageal basal cells: 48.7;Gastric progenitor cells: 103.8;Leydig cells: 92.6;Megakaryocyte progenitors: 52.7;Migrating cytotrophoblasts: 52.0;Monocyte progenitors: 57.6;Mucous neck cells: 60.0;Paneth cells: 170.2" "Cell type enhanced" "Detected in many" "Leydig cells: 92.6;Proliferating cells: 109.7;Secretory gland support: 170.2;Stem cells: 206.7" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 35.7;LAMP5-LHX6 and Chandelier: 37.4" "Cancer enhanced" "Detected in all" "Rectum Adenocarcinoma (TCGA): 92.1" "Region enriched" "Detected in many" 6 "choroid plexus: 12.2" "Immune cell enhanced" "Detected in many" "T-reg: 8.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA005565 Supported Nucleoplasm,Cytosol No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 27: Non-specific - Cell proliferation" 2 "Nucleoplasm, Cytosol" "HPA005565: " "unprognostic (2.03e-1)" "unprognostic (1.56e-3)" "unprognostic (1.25e-1)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (8.67e-2)" "unprognostic (1.42e-1)" "unprognostic (3.42e-1)" "unprognostic (7.38e-2)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (1.16e-7)" "unprognostic (2.06e-3)" "potential prognostic unfavorable (7.85e-6)" "unprognostic (2.66e-3)" "unprognostic (3.32e-3)" "unprognostic (8.00e-2)" "unprognostic (2.87e-2)" "unprognostic (2.72e-2)" "unprognostic (4.35e-2)" "unprognostic (1.62e-1)" "unprognostic (1.04e-2)" "unprognostic (3.64e-1)" "unprognostic (2.02e-2)" "unprognostic (4.08e-2)" "unprognostic (1.97e-2)" "unprognostic (1.35e-1)" "unprognostic (1.60e-3)" "unprognostic (2.21e-3)" "unprognostic (2.53e-1)" "unprognostic (1.24e-1)" "unprognostic (2.06e-1)" CDCA7L "JPO2, R1, RAM2" ENSG00000164649 "Cell division cycle associated 7 like" Q96GN5 7 21900899-21945903 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.8" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 180.9;Oocytes: 262.5;Undifferentiated spermatogonia: 81.9" "Cell type enhanced" "Detected in many" "Neutrophils: 180.9;Oocytes: 262.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 32.3;endothelial cell: 22.8;ependymal cell: 35.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 101.4;naive B-cell: 125.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 4 "olfactory bulb: 12.4" "Group enriched" "Detected in some" "B-cells: 14968.1;Oocytes: 9609.6" "Not detected" "Not detected" "HPA027169, HPA074623" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Cytosol" No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 64 "Nucleoplasm, Nucleoli" "Nucleoli fibrillar center, Cytosol" "HPA027169: , HPA074623: " "unprognostic (2.95e-1)" "unprognostic (4.66e-3)" "unprognostic (3.38e-2)" "unprognostic (1.19e-1)" "unprognostic (2.10e-1)" "unprognostic (2.01e-2)" "unprognostic (3.62e-1)" "unprognostic (7.51e-3)" "unprognostic (3.59e-1)" "unprognostic (3.65e-2)" "unprognostic (1.61e-3)" "unprognostic (2.42e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (6.12e-5)" "unprognostic (6.32e-2)" "unprognostic (5.65e-2)" "unprognostic (3.80e-2)" "unprognostic (3.66e-2)" "unprognostic (2.17e-2)" "unprognostic (2.34e-1)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (2.58e-1)" "unprognostic (2.18e-1)" "unprognostic (6.45e-3)" "unprognostic (9.76e-2)" "unprognostic (4.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.35e-1)" "unprognostic (2.47e-1)" "unprognostic (1.63e-1)" CDCA8 "BOR, DasraB, FLJ12042, MESRGP" ENSG00000134690 "Cell division cycle associated 8" Q53HL2 1 37692481-37709719 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;lymphoid tissue: 36.1;testis: 21.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 56.0;Early primary spermatocytes: 98.7;Enteric transient amplifying cells: 45.0;Erythrocyte progenitors: 69.1;Esophageal basal cells: 31.2;Extravillous trophoblasts: 35.0;Gastric progenitor cells: 39.7;Late primary spermatocytes: 45.6;Megakaryocyte progenitors: 42.5;Migrating cytotrophoblasts: 29.9;Monocyte progenitors: 84.0;Neutrophil progenitors: 45.3;Oocytes: 96.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 69.1;Mononuclear phagocytes: 84.0;Oocytes: 96.7;Spermatogenic cell types: 98.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 1118 "Granulosa cells: 111786.7" "Tissue enriched" "Detected in single" 22089 "bone marrow: 2208915.4" "HPA028120, HPA028258, HPA028783, CAB040294" Enhanced Supported "Nucleoplasm,Nucleoli,Cytokinetic bridge" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 31 Nucleoli "Nucleoplasm, Cytokinetic bridge" "CAB040294: , HPA028120: , HPA028258: , HPA028783: " "unprognostic (2.11e-1)" "unprognostic (8.72e-2)" "unprognostic (2.31e-2)" "unprognostic (4.01e-1)" "unprognostic (3.28e-2)" "unprognostic (5.59e-2)" "unprognostic (1.34e-1)" "unprognostic (8.25e-2)" "unprognostic (1.39e-1)" "potential prognostic unfavorable (3.91e-4)" "validated prognostic unfavorable (5.31e-11)" "validated prognostic unfavorable (1.84e-4)" "potential prognostic unfavorable (2.78e-7)" "validated prognostic unfavorable (4.71e-11)" "validated prognostic unfavorable (1.90e-8)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (2.46e-3)" "unprognostic (2.04e-2)" "unprognostic (1.56e-2)" "unprognostic (3.19e-1)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (8.18e-4)" "unprognostic (1.74e-1)" "unprognostic (4.80e-2)" "unprognostic (1.61e-1)" "unprognostic (1.66e-1)" "unprognostic (5.18e-3)" "unprognostic (2.71e-2)" "unprognostic (2.71e-1)" "unprognostic (1.46e-1)" "unprognostic (1.03e-1)" CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 186.0" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1175.0;Endometrial luminal cells: 763.8;Ocular epithelial cells: 1009.0;Pancreatic acinar cells: 821.7;Urothelial cells: 1358.8" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 1358.8;Glandular cells: 1175.0" "Group enriched" "Detected in many" 8 "choroid plexus epithelial cell: 52.1;committed oligodendrocyte precursor: 41.5;fibroblast: 17.4;oligodendrocyte: 53.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 43.1" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 71386361.9" "Low tissue specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 130000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Intestine - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 110 "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: , CAB028364: , CAB072855: , CAB072856: , CAB072857: , HPA004812: " "unprognostic (2.74e-1)" "unprognostic (3.08e-2)" "unprognostic (8.05e-3)" "unprognostic (6.64e-2)" "unprognostic (1.28e-1)" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.33e-2)" "unprognostic (2.21e-1)" "unprognostic (9.84e-2)" "potential prognostic favorable (3.08e-8)" "unprognostic (2.11e-3)" "unprognostic (1.17e-2)" "unprognostic (2.04e-2)" "unprognostic (9.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.61e-2)" "unprognostic (5.62e-2)" "unprognostic (3.69e-3)" "unprognostic (9.81e-2)" "unprognostic (4.14e-1)" "unprognostic (1.66e-2)" "unprognostic (9.66e-3)" "unprognostic (1.57e-1)" "unprognostic (8.58e-3)" "unprognostic (7.03e-2)" "unprognostic (1.23e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-1)" "unprognostic (1.22e-1)" "unprognostic (8.51e-2)" CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 221.7" "Cell type enhanced" "Detected in some" "Early spermatids: 49.3;Extravillous trophoblasts: 69.0;Kupffer cells: 101.5;Late spermatids: 143.2;Lymphatic endothelial cells: 168.1;Migrating cytotrophoblasts: 47.0;Syncytiotrophoblasts: 126.4;Vascular endothelial cells: 243.7" "Group enriched" "Detected in many" 13 "Endothelial cells: 243.7;Mononuclear phagocytes: 101.5;Spermatogenic cell types: 143.2;Trophoblast cells: 126.4" "Cell type enriched" "Detected in some" 4 "endothelial cell: 186.4" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 64.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "ovarian cancer: 12.0;pancreatic cancer: 9.6;Rhabdoid: 12.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 11964794.2;Capillaries: 11822916.3;Glomeruli: 5298902.2;Macrophages: 8015031.0" "Tissue enhanced" "Detected in many" "lung: 245021582.0" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 960000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 19 "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: , HPA075875: " "unprognostic (9.32e-2)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.68e-2)" "unprognostic (8.62e-2)" "unprognostic (3.66e-1)" "unprognostic (9.58e-2)" "unprognostic (5.26e-2)" "unprognostic (6.52e-3)" "unprognostic (1.55e-1)" "validated prognostic favorable (1.37e-7)" "validated prognostic favorable (9.91e-4)" "potential prognostic unfavorable (9.22e-5)" "unprognostic (1.37e-1)" "unprognostic (8.39e-3)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (2.55e-2)" "unprognostic (1.95e-1)" "unprognostic (8.25e-2)" "unprognostic (5.76e-2)" "unprognostic (4.29e-2)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (2.05e-2)" "unprognostic (1.19e-1)" "unprognostic (2.12e-1)" "unprognostic (6.53e-3)" "unprognostic (9.63e-2)" "unprognostic (1.07e-1)" "unprognostic (1.16e-2)" CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 12.2;kidney: 13.8" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 71.3;Cholangiocytes: 101.7;Epididymal efferent duct absorptive cells: 102.8;Erythrocyte progenitors: 159.5;Megakaryocyte progenitors: 112.3;Oligodendrocyte progenitor cells: 66.6;Pericytes: 213.6;Pituicytes/FSCs: 113.4;Proximal tubule cells: 418.8;Schwann cells: 76.1;Vascular smooth muscle cells: 221.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 159.5;Mural cells: 221.5;Renal nephron cells: 418.8" "Cell type enhanced" "Detected in many" "pericyte: 1000.4;vascular associated smooth muscle cell: 631.5" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 63.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 79.9;Ovary Serous Cystadenocarcinoma (TCGA): 33.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.6;ovarian cancer: 81.5;Uterine cancer: 44.9" "Breast - Endothelial cells, Prostate - Endothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 5511621.2;Proximal tubules: 8174760.0" "Tissue enhanced" "Detected in many" "cerebral cortex: 7964810.9;kidney: 12354431.3" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 16000000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: , HPA007403: , HPA007456: " "unprognostic (1.07e-1)" "unprognostic (3.08e-2)" "unprognostic (4.47e-1)" "unprognostic (1.56e-2)" "unprognostic (9.49e-2)" "unprognostic (4.81e-2)" "unprognostic (2.68e-2)" "unprognostic (2.09e-3)" "unprognostic (2.12e-2)" "unprognostic (2.57e-1)" "potential prognostic favorable (2.60e-5)" "unprognostic (6.26e-3)" "unprognostic (1.05e-3)" "unprognostic (2.02e-1)" "unprognostic (1.99e-1)" "unprognostic (6.91e-2)" "unprognostic (9.86e-2)" "unprognostic (1.52e-2)" "unprognostic (3.62e-2)" "unprognostic (3.50e-1)" "unprognostic (1.28e-1)" "unprognostic (1.56e-1)" "unprognostic (6.71e-2)" "unprognostic (1.44e-1)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (8.87e-5)" "unprognostic (7.69e-2)" "unprognostic (2.04e-1)" "unprognostic (7.48e-2)" CDH8 ENSG00000150394 "Cadherin 8" P55286 16 61647242-62037035 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.0;seminal vesicle: 4.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 362.9;Brain inhibitory neurons: 479.3;Gonadotrophs: 83.8;Oligodendrocyte progenitor cells: 64.2;Oligodendrocytes: 163.7;Other brain neurons: 326.1;Retinal amacrine cells: 83.7;Retinal bipolar cells: 71.5" "Cell type enhanced" "Detected in many" "Glial cells: 163.7;Neuronal cells: 479.3;Pituitary endocrine cells: 83.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 9.8;Rhabdoid: 14.1" "Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2870 "Astrocytes and Neuropil: 248806.5;Microglia and Neuropil: 255759.8;Neurons: 356469.6" "Tissue enriched" "Detected in single" 29690 "cerebral cortex: 2969040.1" "HPA014908, HPA076441" Approved Approved "Plasma membrane" NA NA 110000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 5 "Plasma membrane" "HPA014908: , HPA076441: " "unprognostic (8.22e-2)" "unprognostic (3.82e-2)" "unprognostic (4.84e-2)" "potential prognostic favorable (4.36e-6)" "unprognostic (3.59e-2)" "unprognostic (9.92e-2)" "unprognostic (1.52e-1)" "unprognostic (2.84e-2)" "unprognostic (1.63e-1)" CDK1 "CDC2, CDC28A" ENSG00000170312 "Cyclin dependent kinase 1" P06493 10 60778331-60794852 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Host-virus interaction, Mitosis" "Host cell receptor for virus entry, Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.2;lymphoid tissue: 68.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 83.8;Differentiating spermatogonia: 65.2;Early primary spermatocytes: 67.7;Enteric transient amplifying cells: 76.4;Erythrocyte progenitors: 125.8;Esophageal basal cells: 88.1;Extravillous trophoblasts: 161.3;Gastric progenitor cells: 144.8;Hofbauer cells: 97.9;Late primary spermatocytes: 189.7;Megakaryocyte progenitors: 97.8;Migrating cytotrophoblasts: 143.4;Monocyte progenitors: 159.0;Oocytes: 138.2;Respiratory deuterosomal cells: 70.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 125.8;Mononuclear phagocytes: 159.0;Oocytes: 138.2;Proliferating cells: 144.8;Spermatogenic cell types: 189.7;Trophoblast cells: 161.3" "Group enriched" "Detected in some" 4 "endothelial cell: 4.4;leukocyte: 1.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "NK-cell: 3.3;T-reg: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Somatotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 6898809.4;Neutrophils: 6404364.6" "Group enriched" "Detected in some" "bone marrow: 19428643.9;intestine: 7026052.0" "HPA003387, CAB003799, CAB079974" Enhanced Supported "Nucleoplasm,Cytosol,Acrosome,Perinuclear theca,Connecting piece,Flagellar centriole" NA Yes 44000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 168 "Nucleoplasm, Cytosol" "Acrosome, Perinuclear theca, Connecting piece, Flagellar centriole" "CAB003799: , CAB079974: , HPA003387: " "unprognostic (1.34e-2)" "unprognostic (4.52e-2)" "unprognostic (1.93e-1)" "unprognostic (3.95e-2)" "unprognostic (1.94e-1)" "unprognostic (4.15e-2)" "unprognostic (2.29e-1)" "unprognostic (3.41e-2)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (5.73e-5)" "validated prognostic unfavorable (1.67e-4)" "validated prognostic unfavorable (1.04e-5)" "potential prognostic unfavorable (4.02e-13)" "validated prognostic unfavorable (2.85e-7)" "validated prognostic unfavorable (4.81e-7)" "potential prognostic unfavorable (3.19e-6)" "unprognostic (1.72e-3)" "unprognostic (6.79e-2)" "unprognostic (3.36e-2)" "unprognostic (4.50e-1)" "unprognostic (6.05e-2)" "validated prognostic unfavorable (2.06e-6)" "validated prognostic unfavorable (2.44e-4)" "unprognostic (8.87e-2)" "unprognostic (9.32e-2)" "unprognostic (6.75e-2)" "unprognostic (5.51e-3)" "unprognostic (1.17e-1)" "unprognostic (3.69e-1)" "unprognostic (1.47e-1)" "unprognostic (2.15e-1)" CDK17 "PCTAIRE2, PCTK2" ENSG00000059758 "Cyclin dependent kinase 17" Q00537 12 96278261-96400480 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 390.7;Neutrophil progenitors: 380.4;Neutrophils: 393.8;NK-cells: 522.5;T-cells: 381.5;Vascular endothelial cells: 383.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 721899.6;Neurons: 671302.9" "Group enriched" "Detected in some" 10900 "cerebral cortex: 447605.8;lymphoid tissue: 1732422.9" HPA015325 Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 19 "Nucleoplasm, Cytosol" "HPA015325: " "unprognostic (5.48e-2)" "unprognostic (3.24e-1)" "unprognostic (4.93e-1)" "unprognostic (2.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (2.84e-1)" "unprognostic (4.05e-1)" "unprognostic (5.46e-3)" "unprognostic (4.93e-2)" "unprognostic (1.14e-3)" "unprognostic (3.20e-3)" "unprognostic (2.30e-2)" "unprognostic (2.13e-2)" "unprognostic (2.04e-1)" "unprognostic (4.57e-2)" "unprognostic (2.30e-2)" "unprognostic (1.01e-2)" "unprognostic (7.66e-2)" "unprognostic (8.43e-3)" "unprognostic (1.54e-2)" "unprognostic (2.97e-1)" "unprognostic (4.58e-3)" "unprognostic (2.19e-1)" "unprognostic (1.82e-1)" "unprognostic (2.43e-2)" "unprognostic (2.79e-2)" "unprognostic (1.21e-2)" "unprognostic (3.98e-1)" "unprognostic (5.08e-3)" "unprognostic (1.65e-2)" CDK18 "PCTAIRE3, PCTK3" ENSG00000117266 "Cyclin dependent kinase 18" Q07002 1 205504596-205532793 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 367.7;heart muscle: 116.7" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 552.9" "Cell type enriched" "Detected in many" 4 "Glial cells: 552.9" "Group enriched" "Detected in all" 8 "committed oligodendrocyte precursor: 407.0;oligodendrocyte: 755.9" "Cancer enriched" "Detected in all" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 145.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 6723272.9" "Group enriched" "Detected in many" "cerebral cortex: 10794506.7;intestine: 3432557.7;Stomach: 4675922.3" HPA045429 Approved Approved "Actin filaments,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes No "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Oligodendrocytes - Myelination" 58 "Actin filaments, Cytosol" "Mitotic spindle, Primary cilium, Basal body" "HPA045429: " "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (1.28e-1)" "unprognostic (4.01e-2)" "unprognostic (1.57e-1)" "unprognostic (2.57e-1)" "unprognostic (2.40e-3)" "unprognostic (9.00e-2)" "unprognostic (1.57e-1)" "unprognostic (4.90e-2)" "potential prognostic favorable (1.27e-6)" "unprognostic (1.54e-3)" "unprognostic (2.33e-2)" "unprognostic (6.24e-3)" "unprognostic (1.05e-1)" "unprognostic (9.30e-2)" "unprognostic (3.92e-1)" "unprognostic (8.37e-3)" "unprognostic (9.64e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-2)" "unprognostic (4.53e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-1)" "unprognostic (7.85e-2)" "unprognostic (3.34e-1)" "unprognostic (3.70e-1)" "unprognostic (2.42e-2)" "unprognostic (2.13e-1)" "unprognostic (4.02e-2)" "unprognostic (1.80e-1)" CDK2 ENSG00000123374 "Cyclin dependent kinase 2" P24941 12 55966781-55972789 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 120.3;Extravillous trophoblasts: 99.4;Melanocytes: 141.9;Migrating cytotrophoblasts: 145.1;Syncytiotrophoblasts: 245.2" "Group enriched" "Detected in many" 5 "Pigment cells: 141.9;Trophoblast cells: 245.2" "Cell type enhanced" "Detected in some" "endothelial cell: 13.0;vascular associated smooth muscle cell: 8.0" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 224.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 288.4" "Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 3228710.9" "Group enriched" "Detected in many" "blood vessel: 4358667.5;intestine: 1780759.0;lymphoid tissue: 1813691.3" "CAB013115, HPA066915" Enhanced Approved "Nucleoplasm,Plasma membrane,Centrosome,Basal body,Calyx" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 230 Nucleoplasm "Plasma membrane, Centrosome, Basal body, Calyx" "CAB013115: , HPA066915: " "unprognostic (1.96e-1)" "unprognostic (4.53e-2)" "unprognostic (8.14e-2)" "unprognostic (5.12e-2)" "unprognostic (3.46e-1)" "unprognostic (3.45e-1)" "unprognostic (2.06e-1)" "unprognostic (3.78e-2)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (3.60e-2)" "unprognostic (6.12e-3)" "unprognostic (3.97e-2)" "validated prognostic unfavorable (6.18e-5)" "validated prognostic unfavorable (6.43e-4)" "potential prognostic unfavorable (3.58e-4)" "unprognostic (2.39e-3)" "unprognostic (1.53e-1)" "unprognostic (1.47e-1)" "unprognostic (2.68e-1)" "unprognostic (9.39e-2)" "unprognostic (1.01e-3)" "unprognostic (5.62e-2)" "potential prognostic unfavorable (8.81e-5)" "unprognostic (9.58e-2)" "unprognostic (3.17e-2)" "unprognostic (2.91e-1)" "unprognostic (8.60e-2)" "unprognostic (2.80e-1)" "unprognostic (1.43e-1)" "unprognostic (1.23e-1)" CDK2AP1 "doc-1, DOC1, DORC1, p12DOC-1, ST19" ENSG00000111328 "Cyclin dependent kinase 2 associated protein 1" O14519 12 123250112-123272334 "Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 431.1" "Cell type enhanced" "Detected in many" "Late spermatids: 264.1;Megakaryocytes: 568.7;Platelets: 307.7" "Cell type enhanced" "Detected in all" "Megakaryocytes: 568.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 44.5;intermediate monocyte: 153.2;myeloid DC: 52.6;non-classical monocyte: 176.5" "Group enriched" "Detected in many" 5 "dendritic cells: 52.6;monocytes: 176.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Oocytes: 33941.3" "Tissue enhanced" "Detected in some" "ovary: 385290.4" "CAB019377, HPA057648, HPA068833" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 47: Platelets - Hemostasis" 49 Nucleoplasm Cytosol "CAB019377: , HPA057648: , HPA068833: " "unprognostic (8.31e-2)" "unprognostic (9.40e-2)" "unprognostic (3.86e-2)" "unprognostic (1.41e-1)" "unprognostic (2.17e-1)" "unprognostic (2.94e-3)" "unprognostic (8.71e-2)" "unprognostic (2.20e-1)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (5.85e-4)" "unprognostic (5.95e-3)" "unprognostic (1.78e-2)" "unprognostic (1.97e-3)" "unprognostic (6.99e-3)" "potential prognostic unfavorable (4.68e-4)" "unprognostic (4.05e-3)" "unprognostic (3.57e-2)" "unprognostic (1.14e-2)" "unprognostic (2.21e-1)" "unprognostic (9.55e-2)" "unprognostic (7.39e-2)" "unprognostic (5.92e-3)" "unprognostic (1.53e-1)" "unprognostic (4.30e-1)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (2.27e-1)" "unprognostic (3.95e-2)" "unprognostic (5.98e-2)" "unprognostic (2.84e-1)" "unprognostic (1.60e-1)" CDK3 ENSG00000250506 "Cyclin dependent kinase 3" Q00526 17 76000855-76005999 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 7.0;Bergmann glia: 5.9;Choroid plexus epithelial cells: 3.6;Distal convoluted tubule cells: 7.5;Loop of henle epithelial cells: 6.2;Microglia: 5.5;Oligodendrocyte progenitor cells: 4.8;Oligodendrocytes: 6.1;Other brain neurons: 3.1;Papillary tip epithelial cells: 6.7;Podocytes: 9.8;Proximal tubule cells: 12.4;Renal collecting duct intercalated cells: 6.7;Renal collecting duct principal cells: 4.0;Renal connecting tubule cells: 8.0" "Group enriched" "Detected in some" 5 "Ciliated cells: 3.6;Ductal cells: 8.0;Glial cells: 7.0;Neuronal cells: 3.1;Renal nephron cells: 12.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 29888 "Oocytes: 2988789.7" "Group enriched" "Detected in some" 11758 "bone marrow: 1434177.4;lymphoid tissue: 917449.6" HPA007420 Uncertain Approved Cytosol NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" 40 Cytosol "HPA007420: " "unprognostic (1.68e-2)" "unprognostic (1.17e-1)" "unprognostic (1.71e-1)" "unprognostic (1.85e-1)" "unprognostic (1.21e-1)" "unprognostic (7.43e-2)" "unprognostic (1.06e-2)" "unprognostic (1.26e-2)" "unprognostic (1.60e-3)" "unprognostic (4.79e-3)" "potential prognostic unfavorable (2.58e-6)" "unprognostic (3.58e-2)" "unprognostic (4.54e-2)" "unprognostic (3.40e-2)" "unprognostic (2.37e-2)" "unprognostic (7.80e-2)" "unprognostic (5.20e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-3)" "unprognostic (7.45e-2)" "potential prognostic favorable (2.29e-5)" "potential prognostic favorable (5.20e-5)" "unprognostic (3.21e-3)" "unprognostic (1.08e-2)" "unprognostic (3.90e-2)" "unprognostic (5.78e-3)" "unprognostic (1.26e-2)" "unprognostic (1.49e-1)" "unprognostic (4.30e-1)" "unprognostic (1.33e-1)" "unprognostic (1.95e-2)" CDK4 PSK-J3 ENSG00000135446 "Cyclin dependent kinase 4" P11802 12 57747727-57756013 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 194.8;Esophageal basal cells: 181.0;Hofbauer cells: 196.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 998.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 351103.8" "Tissue enhanced" "Detected in many" "cerebral cortex: 13171520.7" "HPA006024, CAB013116, CAB069405" Supported Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 115 "Nucleoplasm, Cytosol" "Nuclear membrane, Nucleoli" "CAB013116: , CAB069405: , HPA006024: " "unprognostic (1.44e-1)" "unprognostic (5.22e-3)" "unprognostic (1.61e-1)" "unprognostic (5.07e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "unprognostic (2.47e-1)" "unprognostic (1.72e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (8.12e-6)" "potential prognostic favorable (8.58e-4)" "unprognostic (2.61e-3)" "potential prognostic unfavorable (5.35e-4)" "validated prognostic unfavorable (3.43e-6)" "validated prognostic unfavorable (2.85e-8)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (9.36e-3)" "unprognostic (1.85e-2)" "unprognostic (5.25e-3)" "unprognostic (1.42e-1)" "unprognostic (1.85e-1)" "unprognostic (3.44e-1)" "unprognostic (3.14e-1)" "unprognostic (1.86e-1)" "unprognostic (1.10e-2)" "unprognostic (2.36e-3)" "unprognostic (2.24e-1)" "unprognostic (1.07e-1)" "unprognostic (2.11e-2)" "unprognostic (6.45e-3)" CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053815-151057897 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 31.6;Decidual stromal cells: 44.1;Hofbauer cells: 45.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Macrophages" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 15606138.8;Microglia and Neuropil: 18678749.6;Neurons: 19933095.6;Oocytes: 15440828.7" "Tissue enriched" "Detected in many" "cerebral cortex: 38225637.8" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 78: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 91 "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: " "unprognostic (1.69e-1)" "unprognostic (2.79e-2)" "unprognostic (1.61e-1)" "unprognostic (2.53e-2)" "unprognostic (3.80e-2)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (4.08e-5)" "unprognostic (2.33e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (7.70e-5)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (5.91e-4)" "unprognostic (5.38e-2)" "potential prognostic unfavorable (7.49e-5)" "unprognostic (5.36e-3)" "unprognostic (1.78e-1)" "unprognostic (1.57e-2)" "unprognostic (7.11e-3)" "unprognostic (2.30e-1)" "unprognostic (1.88e-3)" "unprognostic (1.72e-1)" "unprognostic (6.34e-2)" "unprognostic (3.30e-1)" "unprognostic (5.34e-2)" "unprognostic (1.63e-1)" "unprognostic (9.40e-2)" "unprognostic (2.67e-1)" "unprognostic (9.98e-3)" "unprognostic (2.83e-1)" "unprognostic (3.74e-2)" "unprognostic (2.54e-2)" CDK5RAP1 "C20orf34, C42, CGI-05, HSPC167" ENSG00000101391 "CDK5 regulatory subunit associated protein 1" Q96SZ6 20 33358839-33401561 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 109.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Distal tubules: 605015.1" "Not detected" "Not detected" "HPA051329, HPA055429" Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 79: Photoreceptor cells - Phototransduction" 3 Mitochondria "Nucleoplasm, Cytosol" "HPA051329: , HPA055429: " "unprognostic (9.43e-2)" "unprognostic (2.51e-2)" "unprognostic (1.61e-2)" "unprognostic (9.23e-2)" "unprognostic (3.50e-1)" "unprognostic (2.10e-1)" "unprognostic (3.75e-1)" "unprognostic (6.55e-3)" "unprognostic (8.46e-2)" "unprognostic (6.80e-3)" "unprognostic (1.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (2.22e-2)" "unprognostic (2.01e-1)" "unprognostic (6.85e-3)" "unprognostic (5.02e-2)" "unprognostic (2.38e-2)" "unprognostic (9.94e-2)" "unprognostic (4.36e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (7.99e-5)" "unprognostic (2.05e-2)" "unprognostic (1.77e-3)" "unprognostic (9.16e-3)" "unprognostic (1.18e-1)" "unprognostic (1.70e-1)" "unprognostic (7.78e-2)" "unprognostic (6.27e-2)" "unprognostic (7.26e-2)" CDK5RAP2 "C48, CEP215, FLJ10867, MCPH3" ENSG00000136861 "CDK5 regulatory subunit associated protein 2" Q96SN8 9 120388875-120580170 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 345.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 554242.5;Fallopian tube cells: 751927.6" "Tissue enriched" "Detected in single" 2672 "bone marrow: 267237.5" "HPA035820, HPA035821, HPA046529, CAB079753" Approved Supported "Cell Junctions,Centrosome,Basal body,Cytosol,Equatorial segment,Mid piece,Principal piece" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 35 "Centrosome, Basal body" "Cell Junctions, Cytosol, Equatorial segment, Mid piece, Principal piece" "CAB079753: , HPA035820: , HPA035821: , HPA046529: " "unprognostic (1.66e-2)" "unprognostic (3.89e-1)" "unprognostic (2.84e-1)" "unprognostic (4.28e-2)" "unprognostic (2.15e-2)" "unprognostic (1.13e-3)" "unprognostic (2.68e-2)" "unprognostic (2.62e-2)" "unprognostic (1.60e-1)" "unprognostic (2.17e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (5.64e-3)" "unprognostic (1.62e-1)" "unprognostic (3.98e-3)" "unprognostic (1.54e-1)" "unprognostic (4.55e-2)" "unprognostic (2.99e-3)" "unprognostic (9.58e-2)" "unprognostic (1.75e-2)" "unprognostic (4.62e-2)" "unprognostic (6.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.65e-2)" "unprognostic (1.01e-1)" "unprognostic (2.48e-1)" "unprognostic (8.99e-2)" "unprognostic (1.48e-1)" "unprognostic (1.51e-1)" "unprognostic (2.35e-1)" "unprognostic (4.05e-2)" "unprognostic (5.61e-2)" CDK5RAP3 "C53, FLJ13660, HSF-27, IC53, LZAP, MST016, OK/SW-cl.114" ENSG00000108465 "CDK5 regulatory subunit associated protein 3" Q96JB5 17 47967810-47981781 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 69.6;Bergmann glia: 65.0;Foveolar cells: 74.6;Gastric chief cells: 47.0;Oligodendrocytes: 48.1" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 74.6;Glial cells: 69.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 49346385.8" "Low tissue specificity" "Detected in all" "HPA022141, HPA022882, HPA027883" Supported Supported Nucleoli,Vesicles,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Protein processing" 38 Cytosol "Nucleoli, Vesicles" "HPA022141: , HPA022882: , HPA027883: " "unprognostic (2.91e-1)" "unprognostic (3.86e-1)" "unprognostic (1.99e-1)" "unprognostic (1.59e-2)" "unprognostic (8.82e-2)" "unprognostic (3.47e-2)" "unprognostic (2.28e-1)" "unprognostic (1.70e-2)" "unprognostic (1.73e-1)" "unprognostic (1.26e-1)" "unprognostic (2.75e-2)" "unprognostic (2.92e-1)" "unprognostic (3.08e-3)" "unprognostic (1.54e-1)" "unprognostic (5.97e-2)" "unprognostic (1.45e-1)" "unprognostic (2.60e-2)" "unprognostic (3.03e-1)" "unprognostic (1.33e-1)" "unprognostic (1.23e-1)" "unprognostic (1.76e-1)" "unprognostic (1.79e-2)" "unprognostic (1.08e-1)" "unprognostic (9.87e-2)" "unprognostic (8.12e-3)" "unprognostic (1.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.06e-2)" "unprognostic (9.73e-2)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" CDK6 PLSTIRE ENSG00000105810 "Cyclin dependent kinase 6" Q00534 7 92604921-92836573 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 660.2;Hematopoietic stem cells: 1044.2;Megakaryocyte progenitors: 1154.0;Megakaryocyte-Erythroid progenitors: 1460.4;Thymocytes: 1313.6" "Cell type enhanced" "Detected in all" "Megakaryocytes: 1460.4;Stem cells: 1044.2;T-cells: 1313.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "intestine: 5387124.2" "HPA002637, CAB004363" Enhanced Supported Nucleoplasm,Cytosol NA NA 8900 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 11: White matter - Signal transduction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 76 Nucleoplasm Cytosol "CAB004363: , HPA002637: " "unprognostic (4.45e-1)" "unprognostic (6.82e-2)" "unprognostic (1.29e-1)" "unprognostic (8.53e-3)" "unprognostic (1.73e-1)" "unprognostic (6.26e-3)" "unprognostic (2.31e-1)" "unprognostic (1.46e-1)" "unprognostic (1.20e-2)" "unprognostic (1.43e-2)" "unprognostic (1.21e-2)" "unprognostic (7.40e-2)" "unprognostic (1.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.84e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (1.28e-1)" "unprognostic (1.63e-1)" "unprognostic (2.92e-1)" "unprognostic (7.31e-3)" "unprognostic (1.65e-1)" "validated prognostic unfavorable (7.99e-6)" "validated prognostic unfavorable (5.59e-6)" "unprognostic (2.17e-2)" "unprognostic (2.09e-1)" "unprognostic (8.82e-2)" "unprognostic (6.95e-2)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (7.86e-2)" "unprognostic (9.71e-3)" CDK9 "C-2k, CDC2L4, PITALRE, TAK" ENSG00000136807 "Cyclin dependent kinase 9" P50750 9 127785679-127790792 "Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 6432049.8" "Tissue enriched" "Detected in many" "Stomach: 13554025.1" "CAB004216, HPA006738" Supported Approved "Nucleoplasm,Cytoplasmic bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 175 Nucleoplasm "Cytoplasmic bodies" "CAB004216: , HPA006738: " "unprognostic (4.27e-2)" "unprognostic (2.62e-1)" "unprognostic (4.55e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (1.47e-3)" "unprognostic (2.20e-1)" "unprognostic (7.65e-3)" "unprognostic (1.71e-2)" "unprognostic (4.95e-1)" "potential prognostic unfavorable (8.52e-4)" "unprognostic (1.06e-1)" "unprognostic (4.04e-2)" "unprognostic (1.33e-1)" "unprognostic (9.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.87e-1)" "unprognostic (5.35e-2)" "unprognostic (2.53e-2)" "unprognostic (1.99e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-2)" "unprognostic (3.37e-1)" "unprognostic (3.27e-2)" "unprognostic (2.04e-1)" "unprognostic (2.28e-2)" "unprognostic (5.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.30e-1)" "unprognostic (1.13e-1)" "unprognostic (6.11e-3)" CDKL5 "CFAP247, EIEE2, STK9" ENSG00000008086 "Cyclin dependent kinase like 5" O76039 X 18425583-18653629 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 229.4;Cone photoreceptor cells: 223.6;Neutrophils: 228.0;Retinal horizontal cells: 220.4;Urothelial cells: 329.5" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 329.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.7" "Lineage enriched" "Detected in single" 11 "granulocytes: 5.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 7022620.2;Microglia and Neuropil: 11118513.9;Neurons: 8601310.3" "Tissue enriched" "Detected in single" 158438 "cerebral cortex: 15843829.9" "HPA002847, CAB011577" Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 1: Neuronal - Visual perception" "Cluster 69: Urothelial cells - Basic cellular functions" 6 Nucleoplasm "CAB011577: , HPA002847: " "unprognostic (2.51e-1)" "unprognostic (2.35e-2)" "unprognostic (2.38e-1)" "unprognostic (1.28e-1)" "unprognostic (4.05e-2)" "unprognostic (2.60e-1)" "unprognostic (1.92e-1)" "unprognostic (1.63e-1)" "unprognostic (9.89e-2)" "unprognostic (1.08e-2)" "potential prognostic favorable (2.18e-6)" "unprognostic (5.49e-2)" "unprognostic (5.73e-2)" "unprognostic (1.96e-1)" "unprognostic (3.55e-2)" "unprognostic (3.70e-1)" "unprognostic (1.54e-2)" "unprognostic (5.37e-2)" "unprognostic (1.30e-2)" "unprognostic (2.32e-1)" "unprognostic (3.07e-1)" "unprognostic (1.11e-1)" "unprognostic (9.51e-2)" "unprognostic (1.81e-1)" "unprognostic (6.56e-3)" "unprognostic (2.21e-1)" "unprognostic (1.77e-2)" "unprognostic (1.03e-1)" CDKN1A "CAP20, CDKN1, CIP1, P21, p21CIP1, p21Cip1/Waf1, SDI1, WAF1" ENSG00000124762 "Cyclin dependent kinase inhibitor 1A" P38936 6 36676460-36687337 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 860.9;Esophageal apical cells: 585.4;Esophageal suprabasal cells: 571.5;Ocular epithelial cells: 838.6;Platelets: 535.9;Smooth muscle cells: 568.5;Suprabasal keratinocytes: 559.3;Thymic myoid cells: 533.0;Urothelial cells: 765.4;Vascular smooth muscle cells: 707.4" "Cell type enhanced" "Detected in all" "Basal cells: 860.9" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 45.6;choroid plexus epithelial cell: 57.6;endothelial cell: 56.7;ependymal cell: 24.7;vascular associated smooth muscle cell: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 74.9" "Group enriched" "Detected in many" 9 "B-cells: 20.8;dendritic cells: 21.5;monocytes: 74.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Colon - Neutrophils" "Region enhanced" "Detected in all" "olfactory bulb: 76.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000064, HPA005946, CAB069401" Supported Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 191 "Nucleoplasm, Nuclear bodies" "CAB000064: , CAB069401: , HPA005946: " "unprognostic (6.40e-2)" "unprognostic (1.16e-2)" "unprognostic (7.94e-3)" "unprognostic (4.53e-2)" "unprognostic (7.99e-3)" "unprognostic (1.48e-1)" "unprognostic (1.03e-2)" "unprognostic (1.85e-3)" "unprognostic (4.01e-2)" "unprognostic (4.78e-2)" "potential prognostic favorable (1.39e-5)" "unprognostic (1.57e-3)" "potential prognostic favorable (8.47e-5)" "unprognostic (3.20e-2)" "potential prognostic favorable (2.11e-6)" "unprognostic (2.70e-2)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" "unprognostic (2.07e-3)" "unprognostic (4.48e-2)" "unprognostic (1.94e-1)" "unprognostic (5.62e-3)" "unprognostic (2.81e-2)" "unprognostic (2.98e-2)" "unprognostic (2.66e-1)" "unprognostic (2.01e-1)" "unprognostic (2.93e-2)" "unprognostic (4.43e-2)" "unprognostic (4.34e-2)" "unprognostic (1.34e-1)" "unprognostic (6.25e-2)" CDKN1B "KIP1, P27KIP1" ENSG00000111276 "Cyclin dependent kinase inhibitor 1B" P46527 12 12685498-12722369 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Protein kinase inhibitor" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Müller glia: 187.9;Neutrophils: 254.4;T-cells: 184.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 978743.4;Skeletal myofibers: 1113090.1;T-cells: 937675.2" "Tissue enhanced" "Detected in many" "ovary: 10550934.7" "CAB003691, CAB021888, HPA064413" Approved Supported "Nucleoplasm,Primary cilium,Primary cilium transition zone,Centrosome,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 134 "Nucleoplasm, Centrosome" "Primary cilium, Primary cilium transition zone, Basal body, Cytosol" "CAB003691: , CAB021888: , HPA064413: " "potential prognostic favorable (6.08e-4)" "unprognostic (3.16e-2)" "unprognostic (1.42e-1)" "unprognostic (2.69e-1)" "unprognostic (1.42e-2)" "unprognostic (2.32e-1)" "unprognostic (1.47e-1)" "unprognostic (2.26e-2)" "unprognostic (2.92e-2)" "unprognostic (4.69e-3)" "potential prognostic favorable (1.19e-5)" "unprognostic (3.15e-3)" "unprognostic (9.23e-2)" "unprognostic (1.52e-2)" "unprognostic (4.28e-3)" "unprognostic (7.66e-2)" "unprognostic (1.15e-1)" "unprognostic (8.87e-3)" "unprognostic (5.64e-2)" "unprognostic (1.11e-2)" "unprognostic (8.48e-2)" "unprognostic (5.31e-2)" "unprognostic (1.50e-2)" "unprognostic (4.41e-1)" "unprognostic (3.37e-2)" "unprognostic (1.71e-2)" "unprognostic (3.84e-2)" "unprognostic (2.43e-1)" "unprognostic (1.51e-1)" "unprognostic (2.39e-2)" "unprognostic (4.25e-1)" CDKN2A "ARF, CDK4I, CDKN2, CMM2, INK4, INK4a, MLM, MTS1, p14, p14ARF, p16, P16-INK4A, p16INK4a, p19, p19Arf" ENSG00000147889 "Cyclin dependent kinase inhibitor 2A" "P42771, Q8N726" 9 21967752-21995301 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, rRNA processing, Transcription, Transcription regulation, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 42.5;pituitary gland: 35.7" "Cell type enhanced" "Detected in many" "Early spermatids: 202.4;Endometrial ciliated cells: 94.1;Gastric progenitor cells: 511.4;Late primary spermatocytes: 158.1;Late spermatids: 681.3;Somatotrophs: 86.7" "Group enriched" "Detected in many" 6 "Proliferating cells: 511.4;Spermatogenic cell types: 681.3" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 28.1;choroid plexus epithelial cell: 63.1;leukocyte: 20.2" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 355.6;Ovary Serous Cystadenocarcinoma (TCGA): 419.0" "Region enriched" "Detected in all" 5 "choroid plexus: 57.4" "Immune cell enhanced" "Detected in many" "T-reg: 37.5" "Group enriched" "Detected in many" 6 "B-cells: 15.7;T-cells: 37.5" "Cancer enhanced" "Detected in many" "cervical cancer: 497.2" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "bone marrow: 1011061.0" "CAB000093, CAB000445, CAB018232, HPA073143" Enhanced Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 125 Nucleoplasm "Primary cilium, Primary cilium tip, Primary cilium transition zone, Cytosol" "CAB000093: , CAB000445: , CAB018232: , HPA073143: " "unprognostic (3.08e-1)" "unprognostic (7.60e-2)" "unprognostic (1.33e-1)" "unprognostic (1.91e-2)" "unprognostic (5.10e-3)" "potential prognostic unfavorable (8.69e-4)" "unprognostic (1.36e-1)" "potential prognostic favorable (7.53e-5)" "potential prognostic favorable (6.09e-5)" "unprognostic (2.67e-3)" "unprognostic (9.17e-3)" "unprognostic (5.78e-2)" "unprognostic (1.35e-1)" "validated prognostic unfavorable (2.16e-5)" "validated prognostic unfavorable (9.98e-6)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (9.24e-3)" "unprognostic (7.82e-2)" "unprognostic (2.93e-1)" "unprognostic (8.81e-2)" "unprognostic (5.88e-3)" "unprognostic (9.23e-2)" "unprognostic (1.42e-1)" "unprognostic (8.61e-3)" "unprognostic (2.17e-1)" "unprognostic (2.30e-2)" "unprognostic (2.84e-2)" "unprognostic (1.43e-1)" "unprognostic (3.26e-2)" "unprognostic (3.09e-2)" "unprognostic (4.05e-3)" CDKN2B "CDK4I, INK4B, MTS2, P15, p15INK4b, TP15" ENSG00000147883 "Cyclin dependent kinase inhibitor 2B" P42772 9 22002903-22009305 "Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.2;intestine: 29.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 107.3;Colonocytes: 232.6;Enterocytes: 201.6;Esophageal apical cells: 558.1;Esophageal suprabasal cells: 283.8;Ocular epithelial cells: 270.2;Suprabasal keratinocytes: 125.7;Urothelial cells: 185.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 558.1;Barrier epithelial cells: 270.2;Enterocytes: 232.6;Suprabasal cells: 283.8" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 11.5;endothelial cell: 5.4" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 46.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 3.3;intermediate monocyte: 3.3;non-classical monocyte: 9.0" "Lineage enriched" "Detected in single" 17 "monocytes: 9.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 457 "lung: 45672.1" "CAB000349, HPA052838, HPA063327, HPA073143" Uncertain Approved "Nucleoplasm,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 26 "Nucleoplasm, Primary cilium transition zone" "Primary cilium, Primary cilium tip, Cytosol" "CAB000349: , HPA052838: , HPA063327: , HPA073143: " "unprognostic (2.07e-2)" "unprognostic (1.11e-1)" "unprognostic (6.57e-2)" "unprognostic (7.39e-2)" "unprognostic (6.69e-2)" "unprognostic (1.52e-2)" "unprognostic (3.55e-1)" "potential prognostic favorable (1.61e-6)" "unprognostic (1.22e-1)" "unprognostic (5.47e-2)" "validated prognostic favorable (9.92e-7)" "validated prognostic favorable (2.84e-4)" "unprognostic (2.53e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (8.70e-2)" "unprognostic (1.36e-1)" "unprognostic (9.08e-3)" "unprognostic (1.58e-1)" "unprognostic (2.14e-1)" "unprognostic (2.63e-1)" "unprognostic (4.20e-2)" "unprognostic (1.44e-1)" "unprognostic (1.33e-3)" "unprognostic (4.35e-2)" "unprognostic (4.54e-2)" "unprognostic (2.00e-2)" "unprognostic (5.65e-2)" "unprognostic (1.75e-2)" "unprognostic (9.07e-2)" "unprognostic (2.35e-1)" "unprognostic (3.02e-3)" CDS2 ENSG00000101290 "CDP-diacylglycerol synthase 2" O95674 20 5126879-5197887 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 209.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 19616026.0;Neurons: 31189982.5" "Tissue enhanced" "Detected in many" "cerebral cortex: 50120784.8" HPA019698 Approved Approved "Endoplasmic reticulum" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 24: Neutrophils - Innate immunity signal integration" 68 "Endoplasmic reticulum" "HPA019698: " "unprognostic (1.36e-2)" "unprognostic (8.54e-2)" "unprognostic (4.03e-2)" "unprognostic (3.37e-2)" "unprognostic (1.57e-1)" "unprognostic (4.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.74e-2)" "unprognostic (2.00e-1)" "unprognostic (2.23e-2)" "validated prognostic favorable (1.47e-7)" "validated prognostic favorable (3.17e-4)" "unprognostic (6.38e-3)" "unprognostic (4.43e-2)" "unprognostic (9.08e-2)" "unprognostic (1.55e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (2.80e-4)" "unprognostic (4.46e-1)" "unprognostic (2.47e-2)" "unprognostic (8.10e-2)" "unprognostic (2.18e-3)" "unprognostic (2.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (5.32e-2)" "unprognostic (2.53e-1)" "unprognostic (3.59e-2)" "unprognostic (2.76e-1)" "unprognostic (1.79e-1)" "unprognostic (7.63e-2)" CDV3 H41 ENSG00000091527 "CDV3 homolog" Q9UKY7 3 133573686-133590261 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 394.3;Late spermatids: 959.4;Plasma cells: 377.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 959.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA029761, HPA029762, HPA029763" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 870000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 2 Cytosol "Nucleoli, Plasma membrane" "HPA029761: , HPA029762: , HPA029763: " "unprognostic (5.87e-3)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (1.33e-3)" "unprognostic (5.97e-2)" "unprognostic (1.12e-1)" "unprognostic (5.42e-2)" "unprognostic (5.33e-2)" "unprognostic (1.86e-1)" "unprognostic (3.20e-2)" "potential prognostic favorable (5.56e-4)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (1.39e-3)" "unprognostic (3.04e-2)" "unprognostic (5.13e-2)" "unprognostic (4.52e-1)" "unprognostic (2.79e-1)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (7.12e-5)" "unprognostic (3.86e-3)" "unprognostic (1.00e-2)" "unprognostic (2.48e-2)" "unprognostic (7.72e-2)" "unprognostic (2.06e-1)" "unprognostic (3.79e-2)" "unprognostic (6.09e-2)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" "unprognostic (1.40e-1)" CDX2 CDX3 ENSG00000165556 "Caudal type homeobox 2" Q99626 13 27960918-27969315 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 45.1" "Cell type enhanced" "Detected in some" "Colonocytes: 284.5;Enteric stem cells: 219.3;Enteric transient amplifying cells: 192.9;Enterocytes: 216.6;Goblet cells: 193.7;Neuroendocrine cells: 52.6;Paneth cells: 150.8;Tuft cells: 46.1" "Cell type enhanced" "Detected in some" "Enterocytes: 284.5;Goblet cells: 193.7;Proliferating cells: 192.9;Secretory gland support: 150.8;Stem cells: 219.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Colon Adenocarcinoma (TCGA): 84.0;Rectum Adenocarcinoma (TCGA): 90.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "colorectal cancer: 73.2" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 132 "lymphoid tissue: 13209.1" "CAB002221, HPA045669, HPA072152" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 8 Nucleoplasm "Vesicles, Cytosol" "CAB002221: , HPA045669: , HPA072152: " "unprognostic (1.84e-1)" "unprognostic (4.16e-1)" "unprognostic (5.62e-2)" "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (3.44e-3)" "unprognostic (1.14e-1)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" CEACAM18 ENSG00000213822 "CEA cell adhesion molecule 18" A8MTB9 19 51478539-51491301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 39 "intestine: 21.4" "Cell type enriched" "Detected in some" 6 "Enterocytes: 41.3" "Cell type enriched" "Detected in some" 6 "Enterocytes: 41.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Pancreatic Adenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.0;Gastric cancer: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059487 Uncertain Approved Midbody Yes NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" Midbody "HPA059487: " "unprognostic (5.85e-2)" CEBPA "C/EBP-alpha, CEBP" ENSG00000245848 "CCAAT enhancer binding protein alpha" P49715 19 33299934-33302534 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adipose tissue: 92.7;breast: 67.7;liver: 198.2;skin 1: 115.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 83.8;Cholangiocytes: 70.1;Colonocytes: 75.8;Hepatocytes: 110.7;Hofbauer cells: 113.5;Microglia: 87.3;Monocyte progenitors: 69.5;Suprabasal keratinocytes: 129.4;Syncytiotrophoblasts: 278.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 110.7;Mononuclear phagocytes: 113.5;Suprabasal cells: 129.4;Trophoblast cells: 278.4" "Cell type enriched" "Detected in many" 5 "central nervous system macrophage: 104.2" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 171.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 16.1;classical monocyte: 7.1;intermediate monocyte: 12.3;myeloid DC: 5.1;non-classical monocyte: 15.8" "Group enriched" "Detected in many" 15 "dendritic cells: 5.1;granulocytes: 16.1;monocytes: 15.8" "Cancer enhanced" "Detected in many" "Leukemia: 73.6;liver cancer: 63.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Keratinocytes: 1136135.1" "Group enriched" "Detected in some" 17968 "bone marrow: 2798006.7;liver: 795573.4" "HPA052734, HPA065037, HPA067937" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 138 Nucleoplasm Vesicles "HPA052734: , HPA065037: , HPA067937: " "unprognostic (1.12e-1)" "unprognostic (2.78e-1)" "unprognostic (4.93e-2)" "unprognostic (1.21e-2)" "unprognostic (5.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.32e-1)" "unprognostic (1.97e-2)" "unprognostic (8.48e-2)" "unprognostic (7.15e-2)" "unprognostic (7.66e-2)" "unprognostic (2.14e-1)" "unprognostic (2.33e-3)" "unprognostic (1.97e-1)" "unprognostic (7.83e-2)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.52e-1)" "unprognostic (6.32e-2)" "unprognostic (6.36e-3)" "unprognostic (7.45e-2)" "unprognostic (7.56e-3)" "unprognostic (1.76e-1)" "unprognostic (7.65e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-3)" "unprognostic (3.66e-1)" "unprognostic (1.08e-1)" "unprognostic (1.76e-1)" "unprognostic (3.74e-1)" "unprognostic (6.66e-2)" "unprognostic (3.87e-2)" CEBPB "C/EBP-beta, CRP2, IL6DBP, LAP, NFIL6, TCF5" ENSG00000172216 "CCAAT enhancer binding protein beta" P17676 20 50190830-50192668 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 983.3;monocytes: 936.4;Neutrophils: 2591.5;Syncytiotrophoblasts: 1822.8" "Cell type enhanced" "Detected in all" "Neutrophils: 2591.5;Trophoblast cells: 1822.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 136.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 16.8" "Group enriched" "Detected in many" 8 "granulocytes: 16.8;monocytes: 7.7" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Spleen - Neutrophils_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 4202561.0;Neutrophils: 6001367.0" "Group enriched" "Detected in some" "bone marrow: 2387403.4;lymphoid tissue: 1344357.8" "CAB004213, HPA061355, HPA062267" Supported Enhanced Nucleoplasm Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 82 Nucleoplasm "CAB004213: , HPA061355: , HPA062267: " "unprognostic (7.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.38e-2)" "unprognostic (3.49e-2)" "unprognostic (1.66e-2)" "unprognostic (3.69e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-3)" "unprognostic (1.12e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.63e-6)" "unprognostic (3.46e-2)" "unprognostic (3.29e-3)" "unprognostic (1.95e-1)" "unprognostic (1.75e-1)" "unprognostic (6.39e-3)" "unprognostic (6.95e-2)" "unprognostic (2.33e-3)" "unprognostic (6.25e-3)" "unprognostic (7.59e-3)" "unprognostic (1.15e-1)" "unprognostic (1.79e-3)" "unprognostic (2.08e-3)" "unprognostic (6.58e-2)" "unprognostic (3.83e-1)" "unprognostic (1.20e-2)" "unprognostic (2.73e-2)" "unprognostic (1.30e-2)" "unprognostic (1.14e-1)" "unprognostic (9.91e-3)" "unprognostic (2.55e-1)" CEBPD "C/EBP-delta, CELF, CRP3, NF-IL6-beta" ENSG00000221869 "CCAAT enhancer binding protein delta" P49716 8 47736913-47738164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1717.2;Fallopian secretory cells: 1552.6;Neutrophils: 1639.8;Pericytes: 1319.6;Smooth muscle cells: 1324.7" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in many" "endothelial cell: 186.9;vascular associated smooth muscle cell: 230.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 55.1" "Group enriched" "Detected in many" 5 "granulocytes: 55.1;monocytes: 19.9" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Testis - Endothelial cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6086 "Alveolar cell types: 557041.8;Neutrophils: 660205.9" "Tissue enriched" "Detected in some" "bone marrow: 111290.9" HPA067581 Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 103: Non-specific - Basic cellular processes" 13 Nucleoplasm "HPA067581: " "potential prognostic favorable (1.87e-4)" "potential prognostic favorable (3.33e-4)" "unprognostic (2.75e-3)" "unprognostic (3.87e-2)" "unprognostic (2.20e-1)" "unprognostic (1.22e-2)" "unprognostic (6.68e-3)" "potential prognostic unfavorable (9.94e-4)" "unprognostic (1.62e-2)" "potential prognostic favorable (9.19e-4)" "unprognostic (7.23e-3)" "unprognostic (2.20e-1)" "unprognostic (2.42e-2)" "unprognostic (4.05e-2)" "unprognostic (7.58e-2)" "unprognostic (7.16e-2)" "unprognostic (1.81e-2)" "unprognostic (1.45e-1)" "unprognostic (1.97e-1)" "unprognostic (1.12e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (3.52e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (5.54e-5)" "unprognostic (1.62e-1)" "unprognostic (1.47e-2)" "unprognostic (8.26e-2)" "unprognostic (2.14e-1)" "unprognostic (7.94e-2)" CECR2 KIAA1740 ENSG00000099954 "CECR2 histone acetyl-lysine reader" Q9BXF3 22 17359949-17558151 "Essential proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;retina: 11.8;skeletal muscle: 18.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 245.5;Cone photoreceptor cells: 705.9;Myonuclei: 799.8;Pituicytes/FSCs: 275.9;Pituitary stem cells: 508.5;Podocytes: 251.9;Rod photoreceptor cells: 365.8;Somatotrophs: 254.0;Syncytiotrophoblasts: 287.9;Thymic myoid cells: 299.1" "Cell type enhanced" "Detected in many" "Myocytes: 799.8;Neuronal cells: 705.9;Stem cells: 508.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 6.8" "Colon - Enteric glia cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 364 "Alveolar cell types: 36365.8" "Tissue enriched" "Detected in single" 15708 "fallopian tube: 1570812.5" HPA002943 Approved Approved Nucleoplasm,Vesicles No No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 9 Nucleoplasm Vesicles "HPA002943: " "unprognostic (3.03e-1)" "unprognostic (2.03e-2)" "unprognostic (4.95e-2)" "unprognostic (2.47e-1)" "unprognostic (1.75e-2)" "unprognostic (2.24e-3)" "unprognostic (2.26e-1)" "unprognostic (6.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.62e-1)" "unprognostic (1.17e-1)" "unprognostic (7.14e-2)" "unprognostic (1.96e-1)" "unprognostic (2.33e-1)" "unprognostic (2.36e-1)" CELF2 "BRUNOL3, CUGBP2, Etr-3, NAPOR-2" ENSG00000048740 "CUGBP Elav-like family member 2" O95319 10 10798397-11336675 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing" "Repressor, RNA-binding" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 1537.5;Brain excitatory neurons: 2017.3;Brain inhibitory neurons: 1668.3;Neutrophil progenitors: 2527.5;Neutrophils: 3802.4" "Cell type enhanced" "Detected in all" "Neutrophils: 3802.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 73.4;Myeloma: 50.4" "Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 42905075.4" "Low tissue specificity" "Detected in all" "CAB016395, HPA035813" Enhanced Supported "Nucleoplasm,Vesicles,Midbody ring" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "Vesicles, Midbody ring" "CAB016395: , HPA035813: " "unprognostic (5.92e-3)" "unprognostic (6.94e-2)" "unprognostic (2.26e-2)" "unprognostic (3.34e-2)" "unprognostic (2.41e-2)" "unprognostic (1.24e-1)" "unprognostic (9.21e-2)" "unprognostic (4.02e-3)" "unprognostic (1.66e-3)" "unprognostic (5.22e-2)" "potential prognostic favorable (6.10e-4)" "unprognostic (3.02e-1)" "unprognostic (1.61e-1)" "unprognostic (7.82e-2)" "unprognostic (4.63e-2)" "unprognostic (1.20e-2)" "unprognostic (3.97e-2)" "unprognostic (1.20e-1)" "unprognostic (2.06e-1)" "unprognostic (4.29e-2)" "unprognostic (6.72e-2)" "unprognostic (7.14e-2)" "unprognostic (3.72e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-1)" "unprognostic (7.03e-2)" "unprognostic (2.31e-1)" "unprognostic (1.49e-1)" "unprognostic (1.94e-1)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" CELF4 BRUNOL4 ENSG00000101489 "CUGBP Elav-like family member 4" Q9BZC1 18 37243040-37565827 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 94.3;pituitary gland: 26.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 265.9;Brain excitatory neurons: 341.9;Brain inhibitory neurons: 367.3;Corticotrophs: 186.3;Lactotrophs: 271.7;Other brain neurons: 372.4;Retinal amacrine cells: 865.3;Retinal ganglion cells: 177.7;Retinal horizontal cells: 412.7;Somatotrophs: 367.0;Thyrotrophs: 279.3" "Group enriched" "Detected in many" 5 "Adrenal endocrine cells: 265.9;Neuronal cells: 865.3;Pituitary endocrine cells: 367.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lung cancer: 7.9;Neuroblastoma: 14.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 13451655.4" "Tissue enriched" "Detected in single" 48053 "cerebral cortex: 4805338.9" "HPA013322, HPA037986" Enhanced Supported Nucleoplasm NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" Nucleoplasm "HPA013322: , HPA037986: " "unprognostic (2.19e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.00e-3)" "unprognostic (3.48e-2)" "unprognostic (9.35e-3)" "unprognostic (3.73e-1)" "unprognostic (8.27e-3)" "unprognostic (3.25e-3)" "unprognostic (2.01e-1)" "unprognostic (2.22e-1)" "unprognostic (2.14e-1)" "unprognostic (1.23e-1)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (5.46e-3)" "unprognostic (2.59e-2)" "unprognostic (5.27e-2)" "unprognostic (2.99e-1)" "unprognostic (4.26e-1)" "potential prognostic unfavorable (1.68e-5)" CEMIP2 TMEM2 ENSG00000135048 "Cell migration inducing hyaluronidase 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 87.0;placenta: 74.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 761.6;NK-cells: 1572.1;T-cells: 945.5" "Cell type enhanced" "Detected in all" "NK-cells: 1572.1" "Cell type enhanced" "Detected in all" "endothelial cell: 778.3;leukocyte: 411.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 10917562.0;Neutrophils: 8364118.9" "Tissue enhanced" "Detected in many" "lung: 7920669.5;lymphoid tissue: 6926863.5" "HPA017080, HPA044889" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 130000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 7 "Plasma membrane" "Vesicles, Cytosol" "HPA017080: , HPA044889: " "unprognostic (1.28e-1)" "unprognostic (2.31e-1)" "unprognostic (3.43e-2)" "unprognostic (1.42e-1)" "unprognostic (8.38e-2)" "unprognostic (8.69e-2)" "unprognostic (1.65e-2)" "unprognostic (6.40e-2)" "unprognostic (1.13e-1)" "potential prognostic favorable (5.78e-7)" "unprognostic (7.72e-3)" "unprognostic (1.22e-2)" "unprognostic (5.45e-2)" "unprognostic (2.94e-1)" "unprognostic (3.07e-2)" "unprognostic (6.16e-2)" "unprognostic (2.60e-1)" "unprognostic (5.22e-2)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (6.07e-4)" "unprognostic (1.01e-1)" "unprognostic (6.48e-2)" "unprognostic (7.24e-2)" "unprognostic (1.01e-1)" "unprognostic (3.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.84e-1)" "unprognostic (7.57e-3)" "unprognostic (1.03e-1)" CENATAC "CCDC84, DLNB14" ENSG00000186166 "Centrosomal AT-AC splicing factor" Q86UT8 11 118998138-119015793 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 63.8;Brain excitatory neurons: 65.9;Brain inhibitory neurons: 69.8;Choroid plexus epithelial cells: 203.0;Distal convoluted tubule cells: 91.6;Loop of henle epithelial cells: 66.7;Oligodendrocytes: 63.6;Podocytes: 70.7;Proximal tubule cells: 67.9;Renal collecting duct intercalated cells: 58.5;Renal connecting tubule cells: 85.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 203.0;Ductal cells: 85.2;Renal nephron cells: 91.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 287070.9" "Tissue enriched" "Detected in single" 66 "lymphoid tissue: 6621.4" "HPA039906, HPA071715" Uncertain Approved Nucleoplasm No No "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 14 Nucleoplasm "HPA039906: , HPA071715: " "unprognostic (3.50e-2)" "unprognostic (4.29e-1)" "unprognostic (1.46e-1)" "unprognostic (1.99e-2)" "unprognostic (2.38e-1)" "unprognostic (5.99e-2)" "unprognostic (2.05e-3)" "unprognostic (1.06e-1)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (8.77e-11)" "unprognostic (1.28e-1)" "unprognostic (9.11e-2)" "unprognostic (1.43e-2)" "unprognostic (4.89e-2)" "unprognostic (1.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.99e-1)" "unprognostic (1.62e-2)" "unprognostic (8.01e-3)" "unprognostic (3.88e-2)" "unprognostic (1.52e-3)" "unprognostic (4.70e-2)" "unprognostic (4.11e-2)" "unprognostic (5.57e-2)" "unprognostic (7.30e-3)" "unprognostic (1.32e-1)" "unprognostic (1.88e-1)" "unprognostic (7.60e-2)" "unprognostic (1.26e-1)" CEND1 "BM88, FLJ90066" ENSG00000184524 "Cell cycle exit and neuronal differentiation 1" Q8N111 11 787115-790113 "Predicted membrane proteins" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 277.6" "Cell type enhanced" "Detected in some" "Astrocytes: 16.3;Brain excitatory neurons: 69.5;Brain inhibitory neurons: 53.3;Choroid plexus epithelial cells: 18.3;Corticotrophs: 20.9;Ependymal cells: 21.8;Gonadotrophs: 23.2;Oligodendrocyte progenitor cells: 28.5;Other brain neurons: 58.2;Retinal amacrine cells: 52.2;Retinal bipolar cells: 50.9;Retinal horizontal cells: 42.1" "Cell type enhanced" "Detected in some" "Ciliated cells: 21.8;Glial cells: 28.5;Neuronal cells: 69.5;Pituitary endocrine cells: 23.2" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Glioblastoma Multiforme (TCGA): 41.7;Kidney Chromophobe (TCGA): 33.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.3;Rhabdoid: 27.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Kidney - Ascending Loop of Henle cells, Prostate - Smooth muscle cells, Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 82377293.5;Microglia and Neuropil: 192067021.5;Neurons: 133552114.3" "Tissue enriched" "Detected in many" "cerebral cortex: 223651801.4" HPA042527 Enhanced Supported Approved Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 98: Neurons - Neurotransmission & signaling" 4 Mitochondria "HPA042527: " "unprognostic (8.68e-2)" "potential prognostic unfavorable (2.38e-5)" "unprognostic (1.72e-1)" "unprognostic (2.86e-1)" "unprognostic (1.89e-1)" "unprognostic (4.20e-2)" "potential prognostic favorable (3.27e-4)" "unprognostic (1.11e-3)" "unprognostic (1.72e-1)" "unprognostic (9.19e-3)" "unprognostic (1.96e-1)" CENPC "CENP-C, CENPC1, hcp-4, MIF2" ENSG00000145241 "Centromere protein C" Q03188 4 67468762-67545503 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "salivary gland: 4794876.6" "HPA049740, HPA058252" Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "HPA049740: , HPA058252: " "unprognostic (5.84e-2)" "unprognostic (1.22e-2)" "unprognostic (2.09e-2)" "unprognostic (2.89e-1)" "unprognostic (4.61e-2)" "unprognostic (1.75e-1)" "unprognostic (3.94e-2)" "unprognostic (2.75e-1)" "validated prognostic favorable (2.62e-5)" "validated prognostic favorable (8.88e-5)" "unprognostic (1.18e-3)" "unprognostic (1.69e-3)" "unprognostic (2.14e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (3.30e-1)" "unprognostic (6.49e-2)" "unprognostic (4.34e-2)" "unprognostic (6.74e-2)" "unprognostic (1.45e-1)" "unprognostic (9.51e-3)" "unprognostic (5.06e-3)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (9.42e-2)" "unprognostic (1.36e-1)" "unprognostic (2.47e-1)" CENPF hcp-1 ENSG00000117724 "Centromere protein F" P49454 1 214603185-214664574 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, DNA synthesis, Mitosis, Myogenesis" "Developmental protein" "Cancer-related genes, Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 19.8;lymphoid tissue: 23.7;testis: 7.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 189.9;Enteric transient amplifying cells: 105.0;Erythrocyte progenitors: 597.7;Esophageal basal cells: 104.6;Late primary spermatocytes: 243.5;Megakaryocyte progenitors: 387.8;Monocyte progenitors: 507.8;Neutrophil progenitors: 166.0" "Cell type enhanced" "Detected in many" "Erythrocytes: 597.7;Megakaryocytes: 387.8;Mononuclear phagocytes: 507.8;Spermatogenic cell types: 243.5" "Cell type enhanced" "Detected in many" "ependymal cell: 9.8;leukocyte: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 2600 "Granulosa cells: 361029.7;Pancreas epithelial cells: 193136.0;Pancreatic islets: 225714.9" "Group enriched" "Detected in some" "cerebral cortex: 2071461.1;skeletal muscle: 2871457.1" "HPA052382, HPA064308, CAB070134" Enhanced Supported Nucleoplasm Yes Yes 5000 "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 17: Choroid plexus - Cilium" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 13 Nucleoplasm "CAB070134: , HPA052382: , HPA064308: " "unprognostic (1.86e-1)" "unprognostic (1.68e-1)" "unprognostic (1.46e-1)" "unprognostic (7.58e-2)" "unprognostic (5.23e-2)" "unprognostic (7.69e-2)" "unprognostic (1.46e-1)" "unprognostic (3.82e-2)" "unprognostic (5.29e-2)" "potential prognostic unfavorable (1.17e-5)" "validated prognostic unfavorable (5.29e-6)" "validated prognostic unfavorable (2.58e-7)" "potential prognostic unfavorable (3.29e-8)" "validated prognostic unfavorable (3.46e-5)" "validated prognostic unfavorable (1.26e-5)" "potential prognostic unfavorable (4.12e-5)" "unprognostic (6.11e-3)" "unprognostic (1.79e-2)" "unprognostic (4.77e-2)" "unprognostic (1.62e-1)" "unprognostic (5.51e-2)" "potential prognostic unfavorable (4.13e-4)" "unprognostic (2.16e-3)" "unprognostic (9.68e-3)" "unprognostic (6.37e-2)" "unprognostic (1.99e-2)" "unprognostic (6.04e-2)" "unprognostic (1.77e-2)" "unprognostic (6.12e-2)" "unprognostic (4.44e-2)" "unprognostic (8.05e-3)" CENPV "CENP-V, p30, PRR6" ENSG00000166582 "Centromere protein V" Q7Z7K6 17 16342534-16353656 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 123.5;Early primary spermatocytes: 130.1;Enteric stem cells: 96.2;Enteric transient amplifying cells: 98.9;Enterocytes: 93.1;Gastric progenitor cells: 133.3;Megakaryocytes: 86.5;Paneth cells: 92.8" "Cell type enhanced" "Detected in many" "Proliferating cells: 133.3;Spermatogenic cell types: 130.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.3;memory B-cell: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 26524840.6" "Low tissue specificity" "Detected in many" "HPA042529, HPA042616" Enhanced Supported "Nucleoplasm,Nuclear membrane,Nucleoli,Cytokinetic bridge,Midbody,Cytosol" Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 25 Nucleoplasm "Nuclear membrane, Nucleoli, Cytokinetic bridge, Midbody, Cytosol" "HPA042529: , HPA042616: " "unprognostic (2.63e-2)" "unprognostic (8.90e-2)" "unprognostic (4.12e-1)" "unprognostic (1.34e-2)" "unprognostic (5.58e-2)" "unprognostic (1.53e-1)" "unprognostic (4.51e-2)" "unprognostic (4.71e-2)" "unprognostic (1.64e-1)" "potential prognostic favorable (2.13e-7)" "unprognostic (1.05e-2)" "unprognostic (1.34e-1)" "unprognostic (2.21e-1)" "unprognostic (4.88e-2)" "unprognostic (4.47e-2)" "unprognostic (1.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-3)" "unprognostic (7.18e-2)" "unprognostic (1.15e-1)" "unprognostic (4.17e-2)" "unprognostic (2.76e-1)" "unprognostic (1.57e-1)" "unprognostic (7.00e-3)" "unprognostic (4.08e-1)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "unprognostic (6.03e-3)" "unprognostic (2.00e-1)" CEP112 "CCDC46, MGC33887" ENSG00000154240 "Centrosomal protein 112" Q8N8E3 17 65635537-66192133 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 43.8" "Cell type enhanced" "Detected in many" "Early spermatids: 1527.4;Ependymal cells: 518.4;Lactotrophs: 504.6;Late spermatids: 2282.5;Rod photoreceptor cells: 1137.5" "Cell type enhanced" "Detected in many" "Neuronal cells: 1137.5;Spermatogenic cell types: 2282.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 22.7" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 4365047.6;Oocytes: 1594070.0" "Not detected" "Not detected" HPA069724 Approved "Nucleoplasm,Midbody ring,Centrosome,Cytosol" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 15 "Nucleoplasm, Centrosome" "Midbody ring, Cytosol" "HPA069724: " "unprognostic (1.63e-1)" "unprognostic (3.07e-1)" "unprognostic (8.75e-2)" "unprognostic (4.25e-1)" "unprognostic (6.19e-2)" "unprognostic (7.05e-3)" "potential prognostic unfavorable (7.65e-6)" "unprognostic (4.53e-2)" "unprognostic (4.17e-3)" "unprognostic (7.31e-3)" "unprognostic (2.01e-3)" "unprognostic (7.57e-2)" "unprognostic (6.38e-2)" "unprognostic (5.44e-2)" "unprognostic (4.53e-2)" "unprognostic (9.80e-3)" "unprognostic (1.14e-3)" "unprognostic (2.33e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" "unprognostic (1.39e-2)" "unprognostic (5.49e-3)" "unprognostic (3.89e-2)" "unprognostic (3.56e-1)" "unprognostic (3.21e-3)" "unprognostic (4.56e-2)" "unprognostic (2.69e-2)" "unprognostic (2.87e-1)" "unprognostic (1.83e-2)" "unprognostic (4.87e-2)" CEP120 "CCDC100, FLJ36090" ENSG00000168944 "Centrosomal protein 120" Q8N960 5 123344890-123423592 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 138.7" "Cell type enhanced" "Detected in many" "Neuronal cells: 138.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 9257600.7;Cardiomyocytes: 26917824.3;Fallopian tube cells: 9048147.0" "Tissue enhanced" "Detected in many" "intestine: 2908539.5;ovary: 2324921.2" "HPA028823, HPA051556" Uncertain Uncertain "Microtubules,Mitotic spindle,Cytosol,Perinuclear theca,Flagellar centriole,Mid piece,Annulus" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 "Microtubules, Flagellar centriole, Annulus" "Mitotic spindle, Cytosol, Perinuclear theca, Mid piece" "HPA028823: , HPA051556: " "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "unprognostic (3.92e-1)" "unprognostic (1.33e-1)" "unprognostic (8.95e-2)" "unprognostic (2.06e-1)" "unprognostic (1.51e-1)" "unprognostic (1.17e-1)" "unprognostic (7.48e-2)" "potential prognostic unfavorable (2.63e-4)" "validated prognostic favorable (1.09e-10)" "validated prognostic favorable (5.98e-5)" "unprognostic (4.27e-2)" "unprognostic (2.67e-1)" "unprognostic (1.52e-3)" "unprognostic (4.48e-2)" "unprognostic (2.87e-1)" "unprognostic (7.73e-2)" "unprognostic (1.29e-1)" "unprognostic (3.30e-2)" "unprognostic (6.69e-3)" "unprognostic (3.26e-1)" "unprognostic (2.42e-1)" "unprognostic (1.13e-1)" "unprognostic (5.35e-2)" "unprognostic (1.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.71e-1)" "unprognostic (1.85e-1)" "unprognostic (4.18e-2)" "unprognostic (1.31e-1)" CEP131 "AZ1, AZI1, KIAA1118" ENSG00000141577 "Centrosomal protein 131" Q9UPN4 17 81189593-81222999 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation, Differentiation, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 26.0;Late spermatids: 28.7;Undifferentiated spermatogonia: 34.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 34.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 9035894.3;Neutrophils: 13039938.9" "Group enriched" "Detected in some" "bone marrow: 102940.7;fallopian tube: 120087.8;lymphoid tissue: 394319.2" HPA024019 Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Centriolar satellite,Basal body,Flagellar centriole" Yes No "Cluster 32: Basophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 46 "Centriolar satellite, Basal body, Flagellar centriole" "Microtubules, Cytokinetic bridge, Primary cilium" "HPA024019: " "unprognostic (1.99e-1)" "unprognostic (2.27e-2)" "unprognostic (2.12e-1)" "unprognostic (5.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.39e-1)" "unprognostic (3.58e-2)" "unprognostic (8.83e-2)" "potential prognostic unfavorable (8.99e-4)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (3.86e-2)" "unprognostic (5.96e-2)" "potential prognostic unfavorable (1.02e-5)" "unprognostic (2.51e-1)" "unprognostic (2.58e-2)" "unprognostic (2.02e-1)" "unprognostic (2.45e-2)" "unprognostic (1.02e-1)" "potential prognostic favorable (3.71e-5)" "unprognostic (3.08e-3)" "potential prognostic unfavorable (4.96e-4)" "unprognostic (1.68e-2)" "unprognostic (2.23e-1)" "unprognostic (5.10e-3)" "unprognostic (7.60e-2)" "unprognostic (2.80e-2)" "unprognostic (7.98e-2)" "unprognostic (2.20e-1)" "unprognostic (2.14e-1)" CEP135 "CEP4, FLJ13621, KIAA0635" ENSG00000174799 "Centrosomal protein 135" Q66GS9 4 55948871-56033361 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 129.2;Late primary spermatocytes: 105.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 129.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 38865390.4" "Group enriched" "Detected in some" "bone marrow: 616675.5;fallopian tube: 1818077.5;lymphoid tissue: 1243618.5" HPA041539 Approved "Acrosome,Mid piece,Principal piece,Annulus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 116 "Mid piece, Principal piece" "Acrosome, Annulus" "HPA041539: " "unprognostic (2.70e-2)" "unprognostic (3.99e-2)" "unprognostic (7.31e-2)" "unprognostic (1.55e-2)" "unprognostic (9.31e-2)" "unprognostic (5.68e-2)" "unprognostic (3.71e-1)" "unprognostic (4.64e-1)" "unprognostic (2.98e-2)" "unprognostic (2.62e-3)" "unprognostic (8.97e-3)" "unprognostic (9.38e-2)" "unprognostic (9.70e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (4.29e-3)" "unprognostic (9.03e-2)" "unprognostic (1.72e-1)" "unprognostic (1.17e-1)" "unprognostic (7.97e-2)" "unprognostic (1.95e-1)" "unprognostic (4.53e-3)" "unprognostic (1.40e-1)" "unprognostic (2.64e-2)" "unprognostic (3.40e-2)" "unprognostic (8.78e-3)" "unprognostic (9.39e-2)" "unprognostic (1.64e-1)" "unprognostic (1.59e-2)" "unprognostic (1.19e-1)" CEP162 "C6orf84, KIAA1009, QN1" ENSG00000135315 "Centrosomal protein 162" Q5TB80 6 84124241-84227643 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Early spermatids: 192.7;Ependymal cells: 172.6;Late primary spermatocytes: 187.7;Respiratory ciliated cells: 154.5" "Cell type enhanced" "Detected in all" "Ciliated cells: 172.6;Spermatogenic cell types: 192.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 16964 "Fallopian tube cells: 1696357.1" "Group enriched" "Detected in some" 3771 "fallopian tube: 288883.0;heart muscle: 319966.0;intestine: 522420.0" "HPA030170, HPA030171, HPA030172, HPA030173" Supported Approved "Nucleoplasm,Centriolar satellite,Basal body,Cytosol,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 35 "Nucleoplasm, Cytosol" "Centriolar satellite, Basal body, Connecting piece, Mid piece, Principal piece" "HPA030170: , HPA030171: , HPA030172: , HPA030173: " "unprognostic (1.15e-2)" "unprognostic (3.25e-2)" "unprognostic (5.71e-2)" "unprognostic (1.87e-2)" "unprognostic (1.35e-1)" "unprognostic (3.34e-1)" "unprognostic (2.84e-3)" "potential prognostic favorable (1.62e-5)" "unprognostic (3.00e-3)" "unprognostic (2.62e-1)" "unprognostic (2.94e-1)" "unprognostic (2.59e-1)" "unprognostic (2.37e-2)" "unprognostic (9.57e-2)" "unprognostic (2.53e-2)" "unprognostic (1.62e-1)" "unprognostic (1.98e-3)" "unprognostic (4.78e-3)" "unprognostic (8.55e-2)" "unprognostic (1.15e-1)" "unprognostic (3.28e-1)" "unprognostic (3.65e-2)" "unprognostic (1.40e-1)" CEP164 "KIAA1052, NPHP15" ENSG00000110274 "Centrosomal protein 164" Q9UPV0 11 117314557-117413266 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, DNA damage, DNA repair, Mitosis" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 623.1;Early spermatids: 342.9;Late spermatids: 441.4;Rod photoreceptor cells: 372.5" "Cell type enhanced" "Detected in many" "Neuronal cells: 623.1;Spermatogenic cell types: 441.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 5842185.8;Fallopian tube cells: 2044841.3;Macrophages: 7368357.9;Neutrophils: 6856485.5" "Tissue enriched" "Detected in some" "lymphoid tissue: 1437003.0" "HPA037605, HPA037606, HPA061504" Uncertain Approved "Nucleoplasm,Vesicles,Primary cilium transition zone,Centrosome,Equatorial segment,Principal piece" NA NA "Cluster 32: Basophils - Transcription" "Cluster 8: Pancreas - Proteolysis" "Cluster 6: Non-specific - Immune response" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 17 "Primary cilium transition zone, Centrosome, Principal piece" "Nucleoplasm, Vesicles, Equatorial segment" "HPA037605: , HPA037606: , HPA061504: " "unprognostic (1.72e-2)" "unprognostic (2.71e-2)" "unprognostic (2.67e-3)" "unprognostic (6.67e-3)" "unprognostic (2.95e-1)" "unprognostic (4.09e-1)" "unprognostic (1.70e-1)" "unprognostic (1.53e-2)" "unprognostic (3.72e-2)" "unprognostic (3.46e-2)" "unprognostic (2.99e-3)" "unprognostic (7.89e-2)" "unprognostic (6.65e-2)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (1.16e-1)" "unprognostic (5.10e-2)" "unprognostic (1.41e-2)" "unprognostic (2.14e-1)" "unprognostic (3.52e-1)" "unprognostic (1.43e-1)" "unprognostic (1.71e-1)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (7.98e-4)" "unprognostic (3.29e-1)" "unprognostic (2.11e-3)" "unprognostic (3.91e-3)" "unprognostic (6.33e-2)" "unprognostic (8.45e-2)" "unprognostic (1.23e-1)" "unprognostic (6.32e-2)" "unprognostic (3.58e-2)" CEP192 "FLJ10352, KIAA1569, PPP1R62" ENSG00000101639 "Centrosomal protein 192" Q8TEP8 18 12991362-13125052 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 291.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 5943315.7" "Tissue enriched" "Detected in many" "intestine: 13760195.2" "HPA039392, HPA040503" Uncertain Uncertain "Centrosome,Basal body,Cytosol" Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 27: Non-specific - Cell proliferation" 36 Cytosol "Centrosome, Basal body" "HPA039392: , HPA040503: " "unprognostic (1.97e-1)" "unprognostic (8.73e-2)" "unprognostic (1.47e-1)" "unprognostic (9.92e-3)" "unprognostic (5.22e-2)" "unprognostic (3.86e-1)" "unprognostic (3.37e-2)" "potential prognostic favorable (3.27e-4)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (1.13e-3)" "unprognostic (6.20e-3)" "unprognostic (3.23e-2)" "unprognostic (7.40e-2)" "unprognostic (2.41e-1)" "unprognostic (1.77e-1)" "unprognostic (4.86e-2)" "unprognostic (1.45e-1)" "unprognostic (6.31e-2)" "unprognostic (2.86e-2)" "unprognostic (1.97e-2)" "unprognostic (1.27e-3)" "unprognostic (1.00e-1)" "unprognostic (1.84e-3)" "unprognostic (1.52e-1)" "unprognostic (2.23e-1)" "unprognostic (2.87e-1)" "unprognostic (2.43e-1)" "unprognostic (3.80e-3)" "unprognostic (1.73e-1)" CEP20 "C16orf63, DKFZp686N1651, FLJ31153, FOPNL, FOR20, PHSECRG2" ENSG00000133393 "Centrosomal protein 20" Q96NB1 16 15865719-15888625 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 304.8;Late primary spermatocytes: 155.9;Late spermatids: 736.2" "Cell type enriched" "Detected in many" 16 "Spermatogenic cell types: 736.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 2088449.6" "Tissue enriched" "Detected in single" 5310 "fallopian tube: 530986.4" HPA040599 Supported Supported "Nucleoplasm,Centriolar satellite,Centrosome,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 24: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 "Centriolar satellite, Centrosome, Basal body" Nucleoplasm "HPA040599: " "unprognostic (7.04e-2)" "unprognostic (2.16e-1)" "unprognostic (3.57e-2)" "unprognostic (4.16e-3)" "unprognostic (8.39e-2)" "unprognostic (8.52e-2)" "unprognostic (5.58e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (1.48e-3)" "unprognostic (2.20e-1)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.41e-1)" "unprognostic (7.68e-2)" "unprognostic (1.77e-1)" "unprognostic (1.12e-1)" "unprognostic (5.06e-2)" "unprognostic (1.11e-1)" "unprognostic (2.10e-2)" "unprognostic (6.33e-3)" "unprognostic (4.86e-2)" "unprognostic (8.41e-2)" "unprognostic (1.59e-2)" "unprognostic (1.98e-1)" "unprognostic (2.72e-1)" "unprognostic (4.69e-2)" "unprognostic (2.79e-1)" "unprognostic (2.44e-2)" "unprognostic (2.28e-2)" CEP290 "3H11Ag, BBS14, CT87, FLJ13615, JBTS5, KIAA0373, LCA10, MKS4, NPHP6, POC3, rd16, SLSN6" ENSG00000198707 "Centrosomal protein 290" O15078 12 88049016-88142099 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" Activator "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Leber congenital amaurosis, Meckel syndrome, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 17728316.4" "Tissue enriched" "Detected in some" "ovary: 6681747.2" "CAB029995, HPA043918, HPA064397" Approved Approved "Primary cilium,Centrosome,Basal body,Mid piece,Principal piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 38: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 44 "Centrosome, Basal body, Mid piece" "Primary cilium, Principal piece" "CAB029995: , HPA043918: , HPA064397: " "unprognostic (1.40e-1)" "unprognostic (2.92e-1)" "unprognostic (1.55e-2)" "unprognostic (8.61e-3)" "unprognostic (5.20e-2)" "unprognostic (1.60e-2)" "unprognostic (2.02e-1)" "unprognostic (3.15e-2)" "unprognostic (1.44e-1)" "unprognostic (2.87e-1)" "unprognostic (7.74e-2)" "unprognostic (9.68e-2)" "unprognostic (2.39e-1)" "unprognostic (9.30e-2)" "unprognostic (7.93e-2)" "unprognostic (4.19e-2)" "unprognostic (2.56e-1)" "unprognostic (4.92e-2)" "unprognostic (1.34e-1)" "unprognostic (6.40e-3)" "unprognostic (1.75e-1)" "unprognostic (3.46e-3)" "unprognostic (6.24e-2)" "unprognostic (2.30e-3)" "unprognostic (1.48e-2)" "unprognostic (8.33e-2)" "unprognostic (2.35e-1)" "unprognostic (1.67e-1)" "unprognostic (2.16e-3)" "unprognostic (1.29e-1)" CEP295NL "DDC8, KIAA1731NL" ENSG00000178404 "CEP295 N-terminal like" Q96MC4 17 78890579-78903217 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 26.1" "Group enriched" "Detected in some" 8 "Early spermatids: 2.0;Late spermatids: 3.4" "Cell type enriched" "Detected in single" 34 "Spermatogenic cell types: 3.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "memory B-cell: 5.5;naive B-cell: 4.4" "Lineage enriched" "Detected in many" 5 "B-cells: 5.5" "Cancer enhanced" "Detected in some" "Myeloma: 4.4" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 906 "skin: 121224.2;Stomach: 59889.7" "HPA023609, HPA024619, HPA025717" Uncertain Approved Vesicles NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Vesicles "HPA023609: , HPA024619: , HPA025717: " "unprognostic (2.91e-1)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (5.86e-5)" "unprognostic (2.77e-3)" CEP350 "CAP350, KIAA0480" ENSG00000135837 "Centrosomal protein 350" Q5VT06 1 179954674-180114880 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1017.4;Late spermatids: 1168.8;Neutrophil progenitors: 721.0" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 1168.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Hepatocytes: 17141765.2" "Group enriched" "Detected in many" "cerebral cortex: 3188286.0;ovary: 5316258.1;pancreas: 5928663.5" "HPA028355, HPA028357, HPA030845, CAB079754" Enhanced Supported "Nucleoplasm,Centrosome,Basal body,End piece" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 41 "Nucleoplasm, Centrosome" "Basal body, End piece" "CAB079754: , HPA028355: , HPA028357: , HPA030845: " "unprognostic (1.88e-1)" "unprognostic (6.80e-2)" "unprognostic (2.42e-1)" "unprognostic (7.58e-2)" "unprognostic (1.95e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (4.91e-2)" "unprognostic (2.09e-2)" "unprognostic (7.08e-3)" "potential prognostic favorable (1.54e-4)" "unprognostic (1.72e-2)" "unprognostic (3.02e-2)" "unprognostic (8.51e-2)" "unprognostic (1.95e-1)" "unprognostic (7.91e-2)" "unprognostic (4.82e-2)" "unprognostic (6.76e-2)" "unprognostic (6.58e-2)" "unprognostic (9.98e-2)" "unprognostic (7.90e-3)" "unprognostic (5.92e-2)" "unprognostic (5.99e-2)" "unprognostic (5.18e-2)" "unprognostic (4.88e-2)" "unprognostic (8.64e-2)" "unprognostic (3.73e-2)" "unprognostic (1.16e-1)" "unprognostic (3.15e-1)" "unprognostic (1.41e-2)" "unprognostic (1.38e-1)" CEP41 "DKFZp762H1311, FLJ22445, JBTS15, TSGA14" ENSG00000106477 "Centrosomal protein 41" Q9BYV8 7 130393771-130442433 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Autism, Autism spectrum disorder, Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.3" "Group enriched" "Detected in many" 4 "Early spermatids: 562.2;Late primary spermatocytes: 451.1;Late spermatids: 205.5" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 562.2" "Cell type enhanced" "Detected in all" "ependymal cell: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 2450154.1;Microglia and Neuropil: 2431840.3;Neurons: 2314528.4" "Group enriched" "Detected in many" "bone marrow: 4396890.2;liver: 4038030.2;pancreas: 3428782.0" "HPA024090, HPA062216" Uncertain Supported "Primary cilium,Basal body" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 39: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Primary cilium" "Basal body" "HPA024090: , HPA062216: " "unprognostic (7.96e-2)" "unprognostic (3.17e-2)" "unprognostic (9.52e-3)" "unprognostic (2.37e-3)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.50e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (7.46e-5)" "unprognostic (3.21e-2)" "unprognostic (2.27e-1)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.35e-2)" "unprognostic (3.06e-2)" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-1)" "unprognostic (2.18e-2)" "unprognostic (1.57e-2)" "unprognostic (4.06e-1)" "potential prognostic favorable (6.64e-4)" "unprognostic (1.43e-1)" "unprognostic (1.73e-1)" "unprognostic (4.15e-2)" "unprognostic (6.91e-3)" "unprognostic (6.92e-2)" "unprognostic (7.18e-2)" CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.5;testis: 20.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 22.6;Early primary spermatocytes: 39.4;Early spermatids: 21.1;Enteric transient amplifying cells: 25.7;Esophageal basal cells: 26.9;Extravillous trophoblasts: 21.7;Gastric progenitor cells: 34.6;Hofbauer cells: 20.8;Late primary spermatocytes: 100.9;Megakaryocyte progenitors: 31.1;Monocyte progenitors: 149.7;Neutrophil progenitors: 26.7" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 149.7;Spermatogenic cell types: 100.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Corticotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 6684 "Granulosa cells: 690548.7;Oocytes: 646235.0" "Not detected" "Not detected" HPA023430 Approved Uncertain "Plasma membrane,Midbody,Primary cilium,Centriolar satellite,Cytosol,Connecting piece,Principal piece" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 107 "Plasma membrane, Centriolar satellite" "Midbody, Primary cilium, Cytosol, Connecting piece, Principal piece" "HPA023430: " "unprognostic (1.91e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (7.07e-2)" "unprognostic (4.81e-2)" "unprognostic (8.32e-2)" "unprognostic (1.06e-1)" "unprognostic (9.69e-2)" "potential prognostic unfavorable (1.27e-5)" "validated prognostic unfavorable (1.09e-9)" "validated prognostic unfavorable (1.50e-7)" "potential prognostic unfavorable (1.22e-15)" "validated prognostic unfavorable (7.31e-9)" "validated prognostic unfavorable (4.22e-5)" "potential prognostic unfavorable (5.67e-5)" "unprognostic (1.15e-3)" "unprognostic (1.06e-2)" "unprognostic (3.68e-1)" "unprognostic (6.33e-2)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (1.53e-5)" "unprognostic (1.33e-3)" "unprognostic (4.31e-2)" "unprognostic (2.25e-1)" "unprognostic (8.32e-2)" "unprognostic (5.79e-2)" "unprognostic (5.35e-3)" "unprognostic (7.12e-2)" "unprognostic (9.72e-2)" "unprognostic (2.75e-1)" CEP68 KIAA0582 ENSG00000011523 "Centrosomal protein 68" Q76N32 2 65056354-65087004 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 177.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Collecting ducts: 587327.9;Fallopian tube cells: 1313457.2;Neurons: 523528.2;Oocytes: 624251.0" "Group enriched" "Detected in some" "cerebral cortex: 548524.0;fallopian tube: 163395.6" "HPA040493, HPA040620" Enhanced Approved "Nucleoplasm,Cell Junctions,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 8 "Nucleoplasm, Centriolar satellite" "Cell Junctions, Basal body, Cytosol" "HPA040493: , HPA040620: " "unprognostic (1.35e-1)" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (4.22e-1)" "unprognostic (3.60e-1)" "unprognostic (1.62e-2)" "unprognostic (3.17e-2)" "potential prognostic favorable (4.29e-4)" "unprognostic (8.88e-3)" "unprognostic (1.86e-2)" "validated prognostic favorable (1.05e-8)" "validated prognostic favorable (2.28e-4)" "unprognostic (2.80e-1)" "unprognostic (5.06e-3)" "unprognostic (1.81e-1)" "unprognostic (2.10e-2)" "unprognostic (2.44e-1)" "unprognostic (6.63e-2)" "unprognostic (2.66e-2)" "unprognostic (3.65e-2)" "unprognostic (4.11e-2)" "unprognostic (3.21e-1)" "unprognostic (3.83e-1)" "unprognostic (1.73e-1)" "unprognostic (1.83e-2)" "unprognostic (6.45e-2)" "unprognostic (6.09e-2)" "unprognostic (1.85e-1)" "unprognostic (4.40e-1)" "unprognostic (3.47e-2)" "unprognostic (8.37e-2)" CEP70 "BITE, FLJ13036" ENSG00000114107 "Centrosomal protein 70" Q8NHQ1 3 138494344-138594538 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 260.8;Fallopian tube ciliated cells: 259.6;Late primary spermatocytes: 406.1;Late spermatids: 450.9" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 450.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "gdT-cell: 2.7;MAIT T-cell: 3.3;memory B-cell: 1.7;memory CD4 T-cell: 2.1;memory CD8 T-cell: 2.3;naive B-cell: 1.4;naive CD4 T-cell: 4.0;naive CD8 T-cell: 4.0;NK-cell: 2.2;T-reg: 1.3" "Group enriched" "Detected in many" 10 "B-cells: 1.7;NK-cells: 2.2;T-cells: 4.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 2621921.5" "Not detected" "Not detected" "HPA036941, HPA036942" Enhanced Approved "Nucleoplasm,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 81: Alveolar cells - Lung function" 232 "Nucleoplasm, Primary cilium, Cytosol" "Centrosome, Basal body" "HPA036941: , HPA036942: " "unprognostic (6.92e-3)" "unprognostic (4.31e-2)" "unprognostic (2.47e-1)" "unprognostic (1.23e-2)" "unprognostic (5.04e-2)" "unprognostic (3.20e-1)" "unprognostic (8.63e-2)" "unprognostic (1.91e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (1.91e-2)" "unprognostic (1.28e-1)" "unprognostic (4.87e-2)" "unprognostic (1.37e-1)" "unprognostic (4.08e-1)" "unprognostic (2.28e-2)" "unprognostic (4.64e-1)" "unprognostic (1.54e-1)" "unprognostic (1.30e-1)" "unprognostic (1.11e-1)" "unprognostic (1.37e-1)" "unprognostic (9.97e-3)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (7.80e-4)" "unprognostic (2.69e-2)" "unprognostic (2.90e-2)" "unprognostic (2.34e-2)" "unprognostic (6.40e-2)" "unprognostic (3.10e-1)" "unprognostic (5.64e-3)" "unprognostic (1.72e-1)" CEP72 "FLJ10565, KIAA1519" ENSG00000112877 "Centrosomal protein 72" Q9P209 5 612340-667168 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 7.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 71.5;Early primary spermatocytes: 31.6;Epicardial cells: 40.9;Melanocytes: 181.5;Oocytes: 23.0" "Cell type enhanced" "Detected in many" "Myocytes: 71.5;Pigment cells: 181.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.5" "Group enriched" "Detected in many" 4 "B-cells: 1.6;NK-cells: 4.5;T-cells: 1.7" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Region enriched" "Detected in many" 8 "cerebellum: 14.1" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 717 "Oocytes: 71691.8" "Group enriched" "Detected in some" "bone marrow: 17096740.7;ovary: 8844785.9" "HPA058235, HPA074879" Approved Supported "Centriolar satellite,Centrosome,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 33 "Centriolar satellite, Centrosome" "Basal body" "HPA058235: , HPA074879: " "unprognostic (2.88e-2)" "unprognostic (1.47e-1)" "unprognostic (2.54e-1)" "unprognostic (2.52e-1)" "unprognostic (6.03e-2)" "unprognostic (1.18e-1)" "unprognostic (1.78e-1)" "unprognostic (9.64e-2)" "unprognostic (6.19e-2)" "potential prognostic unfavorable (2.03e-5)" "unprognostic (3.38e-2)" "unprognostic (2.69e-1)" "unprognostic (3.76e-1)" "unprognostic (5.14e-3)" "unprognostic (1.93e-2)" "unprognostic (7.49e-2)" "unprognostic (1.03e-2)" "unprognostic (7.86e-2)" "unprognostic (1.67e-2)" "unprognostic (9.59e-2)" "unprognostic (5.85e-2)" "unprognostic (5.00e-2)" "unprognostic (8.24e-3)" "unprognostic (2.83e-2)" "unprognostic (2.25e-3)" "unprognostic (5.85e-2)" "unprognostic (3.48e-2)" "unprognostic (3.01e-2)" "unprognostic (1.59e-1)" "unprognostic (3.72e-2)" "unprognostic (6.48e-2)" CEP76 "C18orf9, FLJ12542, HsT1705" ENSG00000101624 "Centrosomal protein 76" Q8TAP6 18 12661833-12702777 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 293.0;Late primary spermatocytes: 76.3;Late spermatids: 72.3" "Cell type enriched" "Detected in many" 9 "Spermatogenic cell types: 293.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 9 "cerebellum: 55.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 2023816.7" "Group enriched" "Detected in some" 2711 "fallopian tube: 142329.0;lymphoid tissue: 399906.0" HPA039395 Approved Uncertain "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle,Primary cilium,Cytosol,Perinuclear theca,Flagellar centriole" Yes NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 35: Non-specific - DNA binding" "Cluster 13: Non-specific - Mixed function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 98 "Microtubules, Mitotic spindle, Primary cilium, Perinuclear theca, Flagellar centriole" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039395: " "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (2.22e-1)" "unprognostic (5.18e-2)" "unprognostic (2.41e-1)" "unprognostic (3.36e-1)" "unprognostic (2.69e-1)" "unprognostic (2.78e-3)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (9.48e-5)" "unprognostic (3.21e-3)" "unprognostic (2.97e-2)" "unprognostic (1.11e-1)" "unprognostic (5.31e-3)" "unprognostic (1.04e-3)" "unprognostic (2.07e-1)" "unprognostic (8.06e-2)" "unprognostic (1.96e-2)" "unprognostic (1.17e-3)" "unprognostic (1.32e-2)" "unprognostic (2.74e-1)" "unprognostic (2.53e-1)" "unprognostic (2.18e-2)" "unprognostic (3.89e-2)" "unprognostic (6.12e-2)" "unprognostic (9.98e-2)" "unprognostic (1.13e-2)" "unprognostic (3.33e-2)" "unprognostic (3.17e-1)" "unprognostic (1.63e-1)" "unprognostic (1.32e-1)" CEP89 "CCDC123, FLJ14640" ENSG00000121289 "Centrosomal protein 89" Q96ST8 19 32875925-32971991 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Cardiomyocytes: 986540.1;Fallopian tube cells: 2436467.0" "Group enriched" "Detected in some" 2105 "fallopian tube: 329860.3;ovary: 91124.4" HPA039382 Supported "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 17 Cytosol "Primary cilium, Centrosome, Basal body" "HPA039382: " "unprognostic (2.71e-2)" "unprognostic (3.82e-1)" "unprognostic (1.19e-2)" "unprognostic (2.96e-1)" "unprognostic (1.54e-1)" "unprognostic (1.38e-1)" "unprognostic (9.70e-2)" "unprognostic (4.06e-1)" "unprognostic (3.00e-2)" "unprognostic (4.35e-2)" "unprognostic (1.03e-1)" "unprognostic (5.48e-3)" "unprognostic (1.57e-3)" "unprognostic (7.12e-2)" "unprognostic (2.98e-1)" "unprognostic (2.04e-2)" "unprognostic (1.61e-2)" "unprognostic (1.29e-2)" "unprognostic (3.95e-2)" "unprognostic (1.40e-1)" "unprognostic (4.30e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (8.94e-2)" "unprognostic (1.05e-3)" "potential prognostic favorable (5.27e-4)" "unprognostic (1.23e-1)" "unprognostic (1.71e-1)" "unprognostic (3.00e-1)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" CEP97 "FLJ23047, LRRIQ2" ENSG00000182504 "Centrosomal protein 97" Q8IW35 3 101724534-101770562 "Essential proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 84.6;Oligodendrocyte progenitor cells: 75.9;Oligodendrocytes: 123.2;Respiratory ciliated cells: 92.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 92.3;Glial cells: 123.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in some" "bone marrow: 19459896.1" HPA002980 Uncertain Approved "Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 31 "Centriolar satellite, Centrosome, Cytosol" "Basal body" "HPA002980: " "unprognostic (5.71e-2)" "unprognostic (1.55e-2)" "unprognostic (2.06e-1)" "unprognostic (1.48e-1)" "unprognostic (7.96e-2)" "unprognostic (1.88e-1)" "unprognostic (1.32e-1)" "unprognostic (9.57e-3)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (5.92e-5)" "unprognostic (7.32e-3)" "unprognostic (1.27e-1)" "unprognostic (1.68e-1)" "unprognostic (4.96e-1)" "unprognostic (1.84e-1)" "unprognostic (1.10e-1)" "unprognostic (8.91e-2)" "unprognostic (1.71e-2)" "unprognostic (2.96e-1)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (5.04e-2)" "unprognostic (2.46e-2)" "unprognostic (1.37e-1)" "unprognostic (4.92e-3)" "unprognostic (1.35e-1)" "unprognostic (2.57e-1)" "unprognostic (4.87e-2)" "unprognostic (7.55e-2)" "unprognostic (1.44e-1)" "unprognostic (8.55e-2)" CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 436.8;pituitary gland: 115.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 72.6;Extravillous trophoblasts: 94.5;Hepatic stellate cells: 148.5;Lactotrophs: 109.4;Oligodendrocytes: 679.2;Somatotrophs: 246.6;Thyrotrophs: 226.1" "Cell type enhanced" "Detected in many" "Glial cells: 679.2;Pituitary endocrine cells: 246.6;Stellate cells: 148.5" "Group enriched" "Detected in all" 13 "committed oligodendrocyte precursor: 350.6;oligodendrocyte: 743.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 498 "Collecting ducts: 31573.2;Oocytes: 69619.5;Pancreatic islets: 48280.6" "Not detected" "Not detected" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 65 "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: , HPA051595: " "unprognostic (4.30e-1)" "unprognostic (4.55e-2)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (3.63e-5)" "unprognostic (2.43e-3)" "unprognostic (9.38e-2)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (1.71e-2)" "unprognostic (1.11e-2)" "unprognostic (8.86e-2)" "validated prognostic unfavorable (4.43e-11)" "validated prognostic unfavorable (9.12e-4)" "potential prognostic unfavorable (2.71e-4)" "unprognostic (1.04e-3)" "unprognostic (3.41e-1)" "unprognostic (8.38e-2)" "unprognostic (1.88e-3)" "unprognostic (1.02e-1)" "unprognostic (3.35e-1)" "validated prognostic unfavorable (6.94e-4)" "validated prognostic unfavorable (9.32e-4)" "unprognostic (1.40e-1)" "unprognostic (1.21e-1)" "unprognostic (1.13e-1)" "unprognostic (1.64e-2)" "unprognostic (2.69e-2)" "unprognostic (1.99e-1)" "unprognostic (1.81e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (6.48e-2)" CERS5 "FLJ25304, LASS5, MGC45411, Trh4" ENSG00000139624 "Ceramide synthase 5" Q8N5B7 12 50129289-50167533 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Sphingolipid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 187.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 1176 "fallopian tube: 117636.4" "HPA006780, HPA026589" Approved Approved "Nuclear membrane,Endoplasmic reticulum,Primary cilium" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "Nuclear membrane" "Endoplasmic reticulum, Primary cilium" "HPA006780: , HPA026589: " "unprognostic (1.00e-1)" "unprognostic (8.66e-3)" "unprognostic (1.29e-2)" "unprognostic (2.89e-2)" "unprognostic (2.67e-3)" "unprognostic (5.18e-2)" "unprognostic (3.01e-1)" "unprognostic (1.22e-2)" "unprognostic (2.85e-2)" "potential prognostic unfavorable (1.77e-5)" "unprognostic (4.62e-3)" "unprognostic (5.32e-2)" "unprognostic (5.74e-3)" "unprognostic (5.26e-3)" "unprognostic (8.46e-2)" "potential prognostic favorable (7.64e-5)" "unprognostic (3.72e-1)" "unprognostic (7.77e-2)" "unprognostic (2.76e-1)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (4.17e-1)" "unprognostic (1.78e-2)" "unprognostic (2.15e-1)" "unprognostic (6.45e-2)" "unprognostic (1.52e-1)" "unprognostic (6.27e-2)" "unprognostic (9.76e-2)" "unprognostic (2.68e-2)" CERT1 "CERT, COL4A3BP, GPBP, STARD11" ENSG00000113163 "Ceramide transporter 1" Q9Y5P4 5 75356345-75512138 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 573.4;Neutrophils: 715.8" "Cell type enhanced" "Detected in all" "Neutrophils: 715.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "blood vessel: 11344659.5" "HPA035645, HPA042608" Enhanced Enhanced "Nucleoplasm,Golgi apparatus" NA NA 37000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 19 "Golgi apparatus" Nucleoplasm "HPA035645: , HPA042608: " "unprognostic (4.82e-3)" "unprognostic (1.38e-1)" "unprognostic (7.35e-2)" "unprognostic (8.70e-2)" "unprognostic (1.48e-1)" "unprognostic (8.20e-2)" "unprognostic (2.31e-1)" "unprognostic (7.10e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (4.56e-9)" "unprognostic (5.84e-3)" "unprognostic (5.51e-2)" "unprognostic (2.19e-1)" "unprognostic (1.52e-1)" "unprognostic (1.16e-1)" "unprognostic (3.21e-3)" "unprognostic (1.95e-1)" "unprognostic (1.02e-1)" "unprognostic (2.40e-2)" "unprognostic (9.43e-2)" "unprognostic (9.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (2.23e-1)" "unprognostic (2.74e-1)" "unprognostic (7.73e-2)" "unprognostic (1.62e-1)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" CES1 "CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1" ENSG00000198848 "Carboxylesterase 1" P23141 16 55802851-55833337 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "liver: 2354.1" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 14.6;Early spermatids: 5.7;Fallopian tube ciliated cells: 7.0;Fibroblasts: 6.5;Hepatic stellate cells: 6.5;Hepatocytes: 26.9;Monocyte progenitors: 15.8;monocytes: 6.6;Respiratory ciliated cells: 20.2;Smooth muscle cells: 9.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 20.2;Goblet cells: 14.6;Hepatocytes: 26.9;Mononuclear phagocytes: 15.8" "Cell type enhanced" "Detected in single" "fibroblast: 1.5" "Group enriched" "Detected in all" 8 "Liver Hepatocellular Carcinoma (TCGA): 1511.8;Lung Squamous Cell Carcinoma (TCGA): 489.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 16 "classical monocyte: 109.7;myeloid DC: 114.5" "Group enriched" "Detected in many" 22 "dendritic cells: 114.5;monocytes: 109.7" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 389.4;liver cancer: 290.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Fibroblasts, Liver - Hepatocytes, Skin - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" "Hepatocytes: 1947567436.2" "Tissue enriched" "Detected in all" "liver: 3098626102.5" "HPA012023, HPA046717" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No NA 35000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 108: Fibroblasts - ECM organization" "Endoplasmic reticulum" "HPA012023: , HPA046717: " "unprognostic (8.95e-2)" "unprognostic (2.78e-2)" "unprognostic (1.30e-1)" "unprognostic (1.47e-2)" "unprognostic (1.97e-1)" "unprognostic (5.51e-2)" "unprognostic (4.36e-3)" "unprognostic (1.42e-2)" "unprognostic (2.84e-3)" "unprognostic (6.10e-3)" "unprognostic (1.21e-2)" "unprognostic (1.94e-3)" "unprognostic (4.40e-2)" "unprognostic (7.56e-2)" "unprognostic (5.12e-2)" "unprognostic (2.29e-1)" "unprognostic (4.06e-3)" "unprognostic (2.79e-1)" "unprognostic (1.51e-1)" "unprognostic (3.17e-2)" "unprognostic (1.84e-2)" "unprognostic (2.32e-1)" "unprognostic (1.66e-1)" "unprognostic (1.66e-1)" "unprognostic (2.05e-1)" "unprognostic (7.43e-2)" "unprognostic (8.09e-2)" "unprognostic (7.62e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-2)" "unprognostic (1.81e-1)" CETN1 "CEN1, CETN" ENSG00000177143 "Centrin 1" Q12798 18 580380-582114 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 1230 "testis: 128.4" "Cell type enhanced" "Detected in some" "Early spermatids: 771.1;Late primary spermatocytes: 2025.8;Late spermatids: 494.6" "Cell type enriched" "Detected in some" 148 "Spermatogenic cell types: 2025.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028956, CAB037244, HPA069157" Enhanced Supported "Nucleoplasm,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 23 "Nucleoplasm, Flagellar centriole" "Mid piece, Principal piece" "CAB037244: , HPA028956: , HPA069157: " CETN3 CEN3 ENSG00000153140 "Centrin 3" O15182 5 90392257-90409766 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 121.8" "Group enriched" "Detected in many" 7 "Early primary spermatocytes: 321.5;Late primary spermatocytes: 969.4" "Cell type enriched" "Detected in all" 11 "Spermatogenic cell types: 969.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 1616094.0" "Tissue enhanced" "Detected in many" "bone marrow: 364787.5" "HPA035608, HPA063704" Enhanced Supported "Centrosome,Basal body" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 38 Centrosome "Basal body" "HPA035608: , HPA063704: " "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (5.32e-2)" "unprognostic (5.33e-2)" "unprognostic (6.12e-2)" "unprognostic (4.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.18e-1)" "unprognostic (1.98e-3)" "potential prognostic unfavorable (9.89e-5)" "potential prognostic favorable (3.07e-6)" "unprognostic (1.72e-1)" "unprognostic (2.75e-1)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (5.41e-5)" "unprognostic (2.58e-1)" "unprognostic (3.49e-1)" "unprognostic (9.80e-2)" "unprognostic (2.49e-1)" "unprognostic (1.36e-1)" "unprognostic (4.01e-3)" "unprognostic (2.63e-2)" "unprognostic (1.37e-2)" "unprognostic (6.01e-2)" "unprognostic (9.42e-3)" "unprognostic (1.03e-2)" "unprognostic (9.04e-2)" "unprognostic (2.77e-1)" "unprognostic (1.72e-1)" "unprognostic (3.02e-1)" "unprognostic (1.18e-1)" CFAP20 "C16orf80, fSAP23, GTL3" ENSG00000070761 "Cilia and flagella associated protein 20" Q9Y6A4 16 58113592-58129381 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 402.7;Late primary spermatocytes: 163.3;Late spermatids: 162.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 402.7" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 40310549.7" "Tissue enriched" "Detected in many" "skin: 10838617.3" HPA018195 Uncertain Supported "Nucleoplasm,Equatorial segment,Principal piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 37 "Nucleoplasm, Principal piece" "Equatorial segment" "HPA018195: " "unprognostic (5.18e-3)" "unprognostic (2.97e-3)" "unprognostic (2.97e-1)" "unprognostic (1.83e-1)" "unprognostic (6.38e-2)" "unprognostic (7.07e-2)" "unprognostic (7.71e-2)" "unprognostic (2.68e-3)" "unprognostic (1.23e-1)" "unprognostic (2.08e-3)" "unprognostic (2.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.50e-1)" "unprognostic (2.89e-1)" "unprognostic (8.16e-2)" "unprognostic (2.64e-1)" "unprognostic (1.24e-1)" "unprognostic (7.57e-2)" "unprognostic (1.79e-1)" "unprognostic (3.58e-2)" "unprognostic (4.60e-2)" "unprognostic (2.95e-1)" "unprognostic (2.28e-1)" "unprognostic (1.54e-1)" "unprognostic (5.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.27e-1)" "unprognostic (1.28e-1)" "unprognostic (3.85e-1)" CFAP221 "FAP221, PCDP1" ENSG00000163075 "Cilia and flagella associated protein 221" Q4G0U5 2 119544432-119662251 "Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 27.8;testis: 23.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 165.9;Distal convoluted tubule cells: 178.8;Early spermatids: 171.6;Endometrial ciliated cells: 265.2;Ependymal cells: 688.0;Epididymal efferent duct ciliated cells: 332.8;Fallopian tube ciliated cells: 448.4;Late primary spermatocytes: 203.2;Late spermatids: 489.2;Loop of henle epithelial cells: 209.4;Respiratory ciliated cells: 574.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 688.0;Renal nephron cells: 209.4;Spermatogenic cell types: 489.2" "Cell type enriched" "Detected in all" 4 "ependymal cell: 756.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 3.3" "Adrenal gland - Adrenal cortex cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 8268 "Fallopian tube cells: 826796.4" "Tissue enriched" "Detected in single" 61343 "fallopian tube: 6134271.0" "HPA042501, HPA054164" Supported "Primary cilium,Primary cilium tip,Connecting piece,Flagellar centriole" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" "Primary cilium, Primary cilium tip, Connecting piece, Flagellar centriole" "HPA042501: , HPA054164: " "unprognostic (1.09e-1)" "unprognostic (6.35e-2)" "unprognostic (1.93e-1)" "unprognostic (4.34e-3)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (6.89e-5)" "unprognostic (1.43e-3)" "unprognostic (8.40e-3)" "potential prognostic favorable (8.92e-4)" "unprognostic (7.61e-2)" "unprognostic (7.31e-2)" "unprognostic (3.34e-1)" "unprognostic (2.59e-1)" "unprognostic (2.20e-1)" "unprognostic (1.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.64e-1)" "unprognostic (9.23e-3)" "unprognostic (6.64e-2)" "unprognostic (1.10e-1)" CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.0;fallopian tube: 20.9;testis: 18.6" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 151.3;Endometrial ciliated cells: 207.5;Ependymal cells: 363.9;Epididymal efferent duct ciliated cells: 169.1;Fallopian tube ciliated cells: 185.0;Respiratory ciliated cells: 444.3" "Cell type enriched" "Detected in many" 7 "Ciliated cells: 444.3" "Cell type enhanced" "Detected in all" "ependymal cell: 379.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cancer enhanced" "Detected in many" "cervical cancer: 19.0" "Lung - Respiratory ciliated cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 53513 "Fallopian tube cells: 5351258.5" "Tissue enriched" "Detected in single" 47815 "fallopian tube: 4781534.9" "HPA039902, HPA040005" Supported Supported "Mid piece,End piece" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 34: Ciliated cells - Cilia assembly & function" "Mid piece, End piece" "HPA039902: , HPA040005: " "potential prognostic unfavorable (2.38e-4)" "unprognostic (2.49e-2)" "unprognostic (3.75e-2)" "unprognostic (8.01e-2)" "unprognostic (2.16e-3)" "unprognostic (9.73e-2)" "unprognostic (4.15e-3)" "unprognostic (1.16e-1)" "unprognostic (2.66e-1)" "unprognostic (2.12e-3)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (2.87e-2)" "unprognostic (1.79e-1)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (7.43e-5)" "unprognostic (1.48e-2)" "potential prognostic favorable (9.85e-6)" "unprognostic (1.52e-1)" "unprognostic (1.78e-1)" "unprognostic (1.83e-1)" "unprognostic (2.53e-2)" CFAP36 "BARTL1, CCDC104, MGC15407" ENSG00000163001 "Cilia and flagella associated protein 36" Q96G28 2 55519604-55545079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 1353.3;Late primary spermatocytes: 1182.0" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 1353.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 759974.8;Microglia and Neuropil: 487456.0;Neurons: 818496.2" "Tissue enhanced" "Detected in some" "fallopian tube: 256489.8;lymphoid tissue: 373488.8" "HPA008994, HPA017061" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Primary cilium,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Primary cilium, Cytosol" "HPA008994: , HPA017061: " "unprognostic (9.47e-2)" "unprognostic (6.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.62e-1)" "unprognostic (1.56e-1)" "unprognostic (2.42e-2)" "unprognostic (4.82e-3)" "unprognostic (6.25e-2)" "unprognostic (1.99e-3)" "potential prognostic favorable (2.19e-4)" "unprognostic (4.74e-2)" "unprognostic (2.17e-3)" "unprognostic (5.57e-3)" "unprognostic (1.89e-1)" "unprognostic (3.63e-2)" "unprognostic (1.83e-1)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" "unprognostic (1.38e-2)" "unprognostic (9.17e-2)" "unprognostic (7.38e-3)" "unprognostic (8.55e-2)" "unprognostic (2.01e-1)" "unprognostic (2.28e-1)" "unprognostic (1.81e-2)" "unprognostic (9.32e-2)" "unprognostic (2.10e-2)" "unprognostic (9.71e-2)" "unprognostic (4.05e-2)" CFAP45 "CCDC19, NESG1" ENSG00000213085 "Cilia and flagella associated protein 45" Q9UL16 1 159872364-159900165 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 35.2;fallopian tube: 42.1;testis: 26.7" "Cell type enhanced" "Detected in many" "Early spermatids: 254.8;Endometrial ciliated cells: 136.9;Ependymal cells: 144.2;Epididymal efferent duct ciliated cells: 180.9;Fallopian tube ciliated cells: 310.3;Late primary spermatocytes: 211.1;Late spermatids: 61.4;Respiratory ciliated cells: 343.8" "Group enriched" "Detected in many" 6 "Ciliated cells: 343.8;Spermatogenic cell types: 254.8" "Cell type enriched" "Detected in some" 5 "ependymal cell: 158.8" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 19.4" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "eosinophil: 3.0;neutrophil: 2.4" "Lineage enriched" "Detected in single" 9 "granulocytes: 3.0" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.3" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 211355 "Fallopian tube cells: 21135544.8" "Tissue enriched" "Detected in single" 80854 "fallopian tube: 8085428.9" "HPA042204, HPA043618" Enhanced Uncertain "Nucleoplasm,Basal body,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Nucleoplasm, Mid piece, Principal piece, End piece" "Basal body, Cytosol" "HPA042204: , HPA043618: " "unprognostic (3.02e-2)" "unprognostic (4.19e-2)" "potential prognostic favorable (2.24e-4)" "unprognostic (3.01e-2)" "potential prognostic unfavorable (6.49e-5)" "unprognostic (2.53e-1)" "unprognostic (2.31e-1)" "unprognostic (9.39e-2)" "unprognostic (1.55e-1)" "unprognostic (2.30e-1)" "unprognostic (2.47e-3)" "unprognostic (7.85e-2)" "unprognostic (7.80e-3)" "unprognostic (1.22e-1)" "unprognostic (1.77e-1)" "unprognostic (3.87e-2)" CFAP46 "bA288G11.4, bA288G11.5, bB137A17.2, bB137A17.3, C10orf123, C10orf124, C10orf92, C10orf93, DKFZp434A1721, FLJ25954, TTC40" ENSG00000171811 "Cilia and flagella associated protein 46" Q8IYW2 10 132808392-132942823 "Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 29.3;testis: 39.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 181.4;Cone photoreceptor cells: 111.8;Endometrial ciliated cells: 290.2;Ependymal cells: 592.2;Epididymal efferent duct ciliated cells: 261.9;Fallopian tube ciliated cells: 249.6;Respiratory ciliated cells: 430.3" "Cell type enriched" "Detected in many" 5 "Ciliated cells: 592.2" "Cell type enriched" "Detected in many" 4 "ependymal cell: 519.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 38403 "Fallopian tube cells: 3840289.5" "Tissue enriched" "Detected in single" 1950 "fallopian tube: 194981.6" "HPA037786, HPA038034, HPA038867, HPA038868" Uncertain Approved "Mid piece,Principal piece,Annulus" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 17: Choroid plexus - Cilium" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 34: Ciliated cells - Cilia assembly & function" "Mid piece, Principal piece, Annulus" "HPA037786: , HPA038034: , HPA038867: , HPA038868: " "unprognostic (7.61e-2)" "unprognostic (1.25e-2)" "unprognostic (2.17e-2)" "unprognostic (3.97e-3)" "unprognostic (1.67e-1)" "unprognostic (4.76e-2)" "unprognostic (1.56e-2)" "unprognostic (3.79e-3)" "unprognostic (2.92e-1)" CFAP52 "FLJ37528, WDR16, WDRPUH" ENSG00000166596 "Cilia and flagella associated protein 52" Q8N1V2 17 9576627-9643447 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 37.4;fallopian tube: 54.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 118.5;Endometrial ciliated cells: 225.8;Ependymal cells: 555.1;Epididymal efferent duct ciliated cells: 250.1;Fallopian tube ciliated cells: 370.3;Late primary spermatocytes: 88.6;Respiratory ciliated cells: 504.6" "Cell type enriched" "Detected in many" 6 "Ciliated cells: 555.1" "Cell type enriched" "Detected in many" 5 "ependymal cell: 591.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 333081 "Fallopian tube cells: 33308131.8" "Tissue enriched" "Detected in single" 174875 "fallopian tube: 17487461.6" HPA023247 Enhanced Approved "Microtubules,Primary cilium,Centriolar satellite,Basal body" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" Microtubules "Primary cilium, Centriolar satellite, Basal body" "HPA023247: " "unprognostic (2.24e-2)" "unprognostic (2.72e-1)" "unprognostic (4.26e-2)" "unprognostic (1.84e-2)" "unprognostic (2.50e-2)" "unprognostic (2.76e-1)" "unprognostic (2.19e-1)" "unprognostic (3.21e-1)" "unprognostic (1.47e-1)" "unprognostic (2.21e-3)" "unprognostic (3.19e-1)" "unprognostic (4.86e-2)" "unprognostic (1.49e-2)" CFAP53 "CCDC11, FLJ32743" ENSG00000172361 "Cilia and flagella associated protein 53" Q96M91 18 50227193-50266495 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Developmental protein" "Ciliopathy, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "choroid plexus: 19.4;fallopian tube: 26.8;testis: 76.5" "Group enriched" "Detected in many" 4 "Early spermatids: 699.4;Endometrial ciliated cells: 414.7;Epididymal efferent duct ciliated cells: 409.2;Fallopian tube ciliated cells: 446.2;Late primary spermatocytes: 1365.9;Late spermatids: 741.6;Respiratory ciliated cells: 538.9" "Group enriched" "Detected in many" 18 "Ciliated cells: 538.9;Spermatogenic cell types: 1365.9" "Group enriched" "Detected in all" 7 "choroid plexus epithelial cell: 50.0;ependymal cell: 181.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Group enriched" "Detected in some" 79300 "Capillaries: 10742410.5;Fallopian tube cells: 5117584.0" "Tissue enriched" "Detected in single" 483261 "fallopian tube: 48326125.7" HPA066142 Enhanced Approved "Nucleoplasm,Nuclear membrane,Basal body,Cytosol" NA No "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 107: Ciliated cells - Cilia assembly & function" 23 "Basal body, Cytosol" "Nucleoplasm, Nuclear membrane" "HPA066142: " "unprognostic (1.31e-1)" "unprognostic (1.31e-1)" "unprognostic (2.98e-1)" "unprognostic (2.83e-2)" "unprognostic (1.32e-1)" "unprognostic (3.85e-2)" "unprognostic (1.07e-2)" "potential prognostic favorable (3.22e-4)" "potential prognostic favorable (2.33e-6)" "unprognostic (7.68e-2)" "unprognostic (3.47e-1)" "unprognostic (3.54e-2)" "unprognostic (4.56e-3)" "unprognostic (3.43e-2)" "unprognostic (1.02e-1)" "unprognostic (8.08e-2)" "unprognostic (1.01e-1)" "unprognostic (4.72e-2)" "unprognostic (2.97e-2)" "unprognostic (3.23e-2)" CFAP54 "C12orf55, C12orf63, FLJ31514, FLJ44112" ENSG00000188596 "Cilia and flagella associated protein 54" Q96N23 12 96489571-96875555 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 6.5;retina: 5.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1724.1;Endometrial ciliated cells: 604.5;Ependymal cells: 3174.7;Epididymal efferent duct ciliated cells: 438.2;Fallopian tube ciliated cells: 695.9;Respiratory ciliated cells: 1426.3" "Cell type enriched" "Detected in many" 19 "Ciliated cells: 3174.7" "Group enriched" "Detected in all" 13 "choroid plexus epithelial cell: 1391.7;ependymal cell: 3403.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 20040 "Fallopian tube cells: 2004009.0" "Tissue enriched" "Detected in some" "fallopian tube: 848827.5" HPA039897 Enhanced Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 56: Non-specific - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "Microtubules, Cytokinetic bridge, Primary cilium" "Basal body, Cytosol" "HPA039897: " "unprognostic (1.80e-1)" "unprognostic (3.02e-2)" "unprognostic (1.77e-1)" "unprognostic (2.89e-3)" "unprognostic (5.42e-3)" "unprognostic (2.04e-1)" "unprognostic (1.75e-1)" "unprognostic (4.62e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (1.72e-2)" "unprognostic (3.51e-3)" "unprognostic (1.45e-1)" "unprognostic (2.70e-2)" "unprognostic (5.23e-2)" "unprognostic (1.74e-1)" "unprognostic (3.59e-2)" "unprognostic (4.53e-3)" "unprognostic (2.64e-1)" "unprognostic (6.34e-3)" "unprognostic (4.84e-2)" "unprognostic (6.42e-3)" "unprognostic (3.95e-2)" "unprognostic (7.91e-2)" "unprognostic (3.29e-3)" "unprognostic (2.51e-2)" "unprognostic (1.89e-1)" "unprognostic (3.66e-1)" "unprognostic (4.30e-2)" "unprognostic (2.32e-1)" CFAP57 "FLJ32000, WDR65" ENSG00000243710 "Cilia and flagella associated protein 57" Q96MR6 1 43172330-43254358 "Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 13.2;fallopian tube: 22.0;testis: 14.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 47.6;Endometrial ciliated cells: 118.3;Ependymal cells: 114.6;Epididymal efferent duct ciliated cells: 86.9;Fallopian tube ciliated cells: 188.0;Late primary spermatocytes: 75.3;Late spermatids: 40.6;Respiratory ciliated cells: 232.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 232.8;Spermatogenic cell types: 75.3" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 42.1;ependymal cell: 126.2" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 3.9" "Region enhanced" "Detected in all" "choroid plexus: 23.2" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 4.1;lymphoma: 3.7" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Skin - Inner root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 245291 "Fallopian tube cells: 11196073.7;Microglia and Neuropil: 37862170.9" "Tissue enriched" "Detected in single" 162563 "fallopian tube: 16256284.5" "HPA002736, HPA028623, HPA028629" Enhanced Supported "Primary cilium,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 59: Leukemia - T-cell receptor" "Cluster 107: Ciliated cells - Cilia assembly & function" "Primary cilium, Cytosol" "HPA002736: , HPA028623: , HPA028629: " "unprognostic (4.05e-2)" "unprognostic (5.44e-2)" "unprognostic (1.67e-2)" "unprognostic (6.75e-3)" "unprognostic (2.22e-3)" "unprognostic (5.19e-2)" "unprognostic (5.22e-2)" "unprognostic (2.14e-1)" "unprognostic (1.91e-1)" "unprognostic (1.01e-2)" "unprognostic (5.67e-3)" CFAP97 "DKFZp434F1728, hmw, KIAA1430" ENSG00000164323 "Cilia and flagella associated protein 97" Q9P2B7 4 185159665-185209504 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 244.4;Late primary spermatocytes: 462.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 462.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 1932274.3" "Tissue enriched" "Detected in single" 16416 "fallopian tube: 1641646.9" "HPA049446, HPA053335" Uncertain Approved "Nucleoli fibrillar center,Primary cilium,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 10 "Nucleoli fibrillar center" "Primary cilium, Cytosol" "HPA049446: , HPA053335: " "unprognostic (3.91e-2)" "unprognostic (2.08e-1)" "unprognostic (6.80e-3)" "unprognostic (2.65e-2)" "unprognostic (2.35e-1)" "unprognostic (3.13e-1)" "unprognostic (6.69e-2)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (6.76e-4)" "validated prognostic favorable (2.60e-7)" "validated prognostic favorable (4.13e-4)" "unprognostic (2.07e-1)" "unprognostic (3.63e-3)" "unprognostic (3.06e-2)" "unprognostic (3.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.90e-1)" "unprognostic (1.99e-2)" "unprognostic (2.24e-2)" "unprognostic (1.84e-2)" "unprognostic (5.28e-2)" "unprognostic (3.81e-1)" "unprognostic (3.32e-2)" "unprognostic (9.39e-2)" "unprognostic (5.07e-2)" "unprognostic (4.32e-2)" "unprognostic (4.14e-1)" "unprognostic (2.67e-2)" "unprognostic (2.04e-2)" CFAP99 ENSG00000206113 "Cilia and flagella associated protein 99" D6REC4 4 2418974-2462942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "testis: 15.0" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 24.3;Cone photoreceptor cells: 16.6;Endometrial ciliated cells: 33.3;Ependymal cells: 53.8;Epididymal efferent duct ciliated cells: 25.2;Fallopian tube ciliated cells: 33.7;Late primary spermatocytes: 45.7;Late spermatids: 27.7;Respiratory ciliated cells: 67.4;Rod photoreceptor cells: 16.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 67.4;Neuronal cells: 16.8;Spermatogenic cell types: 45.7" "Group enriched" "Detected in many" 8 "choroid plexus epithelial cell: 18.0;ependymal cell: 56.9" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Pancreatic islets: 43872890.5;T-cells: 51725910.6" "Tissue enriched" "Detected in many" "Stomach: 8954895.1" HPA071642 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Mid piece,Principal piece,End piece" Yes NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Microtubules, Mid piece, Principal piece, End piece" "Cytokinetic bridge, Mitotic spindle" "HPA071642: " "unprognostic (2.45e-1)" CFL2 NEM7 ENSG00000165410 "Cofilin 2" Q9Y281 14 34709113-34714823 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 348.8;skeletal muscle: 674.8;tongue: 640.8" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 194.5;Epididymal clear cells: 175.6;Smooth muscle cells: 373.7;Thymic myoid cells: 274.6" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 373.7;Stromal cells: 274.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 126.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Colon - Smooth muscle cells, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Skeletal myofibers: 270837978.9" "Tissue enriched" "Detected in all" "skeletal muscle: 750989955.7" "CAB037078, HPA045599, HPA077782" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 39000000 "Cluster 24: Non-specific - Transcription" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 62: Smooth muscle cells - Muscle contraction" 29 "Plasma membrane" "Nucleoplasm, Cytosol" "CAB037078: , HPA045599: , HPA077782: " "unprognostic (4.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (2.55e-2)" "unprognostic (2.36e-1)" "unprognostic (4.16e-2)" "unprognostic (7.10e-3)" "unprognostic (2.27e-1)" "unprognostic (4.52e-3)" "potential prognostic unfavorable (1.03e-5)" "potential prognostic favorable (9.97e-6)" "unprognostic (5.05e-2)" "unprognostic (3.76e-1)" "unprognostic (1.54e-1)" "unprognostic (5.94e-2)" "unprognostic (9.00e-2)" "unprognostic (7.80e-2)" "unprognostic (4.16e-2)" "unprognostic (3.89e-3)" "unprognostic (1.70e-1)" "unprognostic (6.99e-2)" "unprognostic (4.22e-2)" "unprognostic (4.88e-2)" "unprognostic (8.14e-2)" "unprognostic (4.20e-2)" "unprognostic (3.74e-2)" "unprognostic (6.70e-2)" "potential prognostic unfavorable (5.12e-5)" "unprognostic (1.50e-1)" "unprognostic (2.63e-3)" "unprognostic (3.54e-2)" CGNL1 "FLJ14957, JACOP, KIAA1749, PCING" ENSG00000128849 "Cingulin like 1" Q0VF96 15 57375967-57550717 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 63.8" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 973.6;Esophageal apical cells: 381.8;Loop of henle epithelial cells: 963.8;Podocytes: 590.0;Prostatic glandular cells: 345.2;Proximal tubule cells: 512.0;Renal collecting duct intercalated cells: 655.1;Renal connecting tubule cells: 312.0;Salivary acinar cells: 282.0" "Cell type enhanced" "Detected in many" "Ductal cells: 655.1;Renal nephron cells: 973.6" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 208.3;endothelial cell: 760.9" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 88.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 34.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 63957994.6;Glomeruli: 74315988.1;Proximal tubules: 73500032.2" "Tissue enhanced" "Detected in many" "intestine: 24718023.2" "CAB013500, HPA056911, HPA069214" Enhanced Supported "Nuclear bodies,Cell Junctions" No No "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 10 "Cell Junctions" "Nuclear bodies" "CAB013500: , HPA056911: , HPA069214: " "unprognostic (3.53e-3)" "unprognostic (2.39e-2)" "unprognostic (1.67e-2)" "unprognostic (2.34e-1)" "unprognostic (4.13e-2)" "unprognostic (1.73e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (6.97e-7)" "unprognostic (1.79e-3)" "unprognostic (4.67e-1)" "potential prognostic favorable (2.83e-6)" "unprognostic (1.43e-2)" "unprognostic (5.21e-2)" "unprognostic (1.46e-3)" "unprognostic (3.37e-3)" "unprognostic (9.15e-3)" "unprognostic (2.72e-1)" "unprognostic (2.27e-1)" "unprognostic (2.37e-1)" "unprognostic (3.73e-2)" "unprognostic (1.19e-1)" "unprognostic (4.53e-2)" "unprognostic (1.44e-1)" "unprognostic (5.77e-2)" "unprognostic (1.21e-2)" "unprognostic (2.16e-1)" "unprognostic (2.25e-1)" "unprognostic (1.51e-2)" "unprognostic (3.79e-1)" "unprognostic (6.20e-3)" "unprognostic (4.13e-2)" CHD2 "DKFZp547I1315, DKFZp686E01200, DKFZp781D1727, FLJ38614" ENSG00000173575 "Chromodomain helicase DNA binding protein 2" O14647 15 92886203-93027996 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 1126.6;Neutrophils: 1760.5" "Cell type enhanced" "Detected in all" "Neutrophils: 1760.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 15394598.8" "Tissue enhanced" "Detected in many" "lung: 1094657.5" "HPA060744, HPA060960" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles" NA NA 24000 "Cluster 20: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 Nucleoplasm "Nucleoli, Golgi apparatus, Vesicles" "HPA060744: , HPA060960: " "unprognostic (7.71e-2)" "unprognostic (3.79e-1)" "unprognostic (2.75e-3)" "unprognostic (4.72e-2)" "unprognostic (7.66e-2)" "unprognostic (2.15e-2)" "unprognostic (2.52e-1)" "unprognostic (4.78e-2)" "unprognostic (2.70e-1)" "unprognostic (2.34e-3)" "potential prognostic favorable (8.65e-4)" "unprognostic (1.06e-3)" "unprognostic (8.80e-3)" "unprognostic (6.43e-3)" "unprognostic (1.33e-1)" "unprognostic (1.99e-2)" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (1.91e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-1)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (8.06e-5)" "unprognostic (4.66e-2)" "unprognostic (9.60e-3)" "unprognostic (5.47e-2)" "unprognostic (4.70e-2)" "unprognostic (8.24e-2)" "unprognostic (4.66e-1)" "unprognostic (6.80e-2)" "unprognostic (9.80e-2)" CHD3 "Mi-2a, Mi2-ALPHA, ZFH" ENSG00000170004 "Chromodomain helicase DNA binding protein 3" Q12873 17 7884796-7912760 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 185.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 13673002.8" "Tissue enriched" "Detected in many" "salivary gland: 1847884.8" "HPA043368, HPA076524" Supported Supported "Nucleoplasm,Nucleoli,Centriolar satellite" No No "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 149 "Nucleoplasm, Nucleoli" "Centriolar satellite" "HPA043368: , HPA076524: " "unprognostic (2.60e-3)" "unprognostic (4.59e-3)" "unprognostic (5.38e-2)" "unprognostic (3.10e-2)" "unprognostic (6.08e-2)" "unprognostic (9.33e-2)" "unprognostic (5.41e-1)" "unprognostic (2.82e-3)" "unprognostic (4.93e-3)" "unprognostic (7.87e-2)" "unprognostic (5.94e-2)" "unprognostic (3.29e-2)" "unprognostic (1.99e-1)" "unprognostic (1.14e-1)" "unprognostic (2.67e-1)" "unprognostic (2.07e-2)" "unprognostic (1.38e-1)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "unprognostic (8.16e-3)" "unprognostic (1.58e-3)" "unprognostic (2.92e-3)" "unprognostic (1.59e-2)" "unprognostic (2.62e-1)" "unprognostic (2.63e-1)" "unprognostic (3.55e-1)" "unprognostic (3.55e-3)" "unprognostic (1.26e-2)" "unprognostic (3.32e-1)" "unprognostic (8.36e-3)" "unprognostic (1.21e-2)" CHD4 "Mi-2b, Mi2-BETA" ENSG00000111642 "Chromodomain helicase DNA binding protein 4" Q14839 12 6570082-6614524 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 83.4;Bergmann glia: 74.8;Choroid plexus epithelial cells: 64.4;Ependymal cells: 70.0;Microglia: 63.1;Oligodendrocytes: 77.9;Other brain neurons: 56.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 70.0;Glial cells: 83.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "lymphoid tissue: 76594226.0" HPA012008 Supported Enhanced "Nucleoplasm,Mitotic spindle,Cytosol" Yes NA 32000 "Cluster 30: Non-specific - DNA binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 221 Nucleoplasm "Mitotic spindle, Cytosol" "HPA012008: " "unprognostic (2.29e-1)" "unprognostic (3.56e-2)" "unprognostic (4.35e-1)" "unprognostic (6.08e-2)" "unprognostic (2.05e-1)" "unprognostic (2.70e-1)" "unprognostic (3.03e-2)" "potential prognostic favorable (5.12e-5)" "unprognostic (1.15e-2)" "unprognostic (5.62e-3)" "potential prognostic favorable (1.43e-4)" "unprognostic (5.72e-3)" "unprognostic (3.57e-1)" "unprognostic (4.12e-3)" "unprognostic (1.81e-1)" "unprognostic (1.64e-1)" "unprognostic (8.98e-2)" "unprognostic (4.69e-2)" "unprognostic (1.85e-1)" "unprognostic (8.56e-3)" "unprognostic (4.44e-1)" "unprognostic (3.23e-1)" "unprognostic (4.83e-3)" "unprognostic (1.16e-2)" "unprognostic (3.49e-1)" "unprognostic (9.90e-2)" "unprognostic (3.44e-2)" "unprognostic (1.71e-1)" "unprognostic (9.60e-2)" "unprognostic (1.39e-1)" "unprognostic (4.23e-2)" CHD9 "BC022889, FLJ12178, KIAA0308" ENSG00000177200 "Chromodomain helicase DNA binding protein 9" Q3L8U1 16 53054991-53329150 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 1655649.7;Pancreas epithelial cells: 5207426.2;Pancreatic islets: 2385760.4" "Tissue enriched" "Detected in some" "pancreas: 119848.8" "HPA042053, HPA049420, HPA066155" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 3 Nucleoplasm Cytosol "HPA042053: , HPA049420: , HPA066155: " "unprognostic (1.96e-2)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (3.38e-1)" "unprognostic (6.57e-2)" "unprognostic (7.46e-2)" "unprognostic (2.33e-2)" "unprognostic (8.37e-2)" "unprognostic (4.07e-3)" "potential prognostic favorable (7.80e-7)" "unprognostic (4.79e-3)" "unprognostic (1.86e-1)" "unprognostic (3.38e-1)" "unprognostic (1.49e-3)" "unprognostic (5.07e-2)" "unprognostic (2.52e-1)" "unprognostic (1.17e-1)" "unprognostic (3.75e-1)" "unprognostic (1.40e-1)" "unprognostic (1.64e-2)" "unprognostic (8.83e-2)" "unprognostic (2.46e-2)" "unprognostic (2.39e-1)" "unprognostic (1.08e-2)" "unprognostic (5.58e-2)" "unprognostic (2.81e-2)" "unprognostic (4.06e-2)" "unprognostic (3.77e-1)" "unprognostic (1.12e-2)" "unprognostic (3.75e-1)" CHID1 "FLJ42707, MGC3234, SI-CLP" ENSG00000177830 "Chitinase domain containing 1" Q9BWS9 11 867859-915058 "Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 251.8;Epididymal principal cells: 254.9;Late spermatids: 722.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 722.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Pancreas epithelial cells: 107917179.5;Pancreatic islets: 101329850.5" "Tissue enriched" "Detected in all" "pancreas: 50051220.5" HPA039374 Uncertain Uncertain "Nucleoplasm,Intermediate filaments" "Intracellular and membrane" Immunity No No 660000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Nucleoplasm, Intermediate filaments" "HPA039374: " "unprognostic (8.10e-2)" "unprognostic (1.41e-1)" "unprognostic (1.91e-1)" "unprognostic (7.20e-2)" "unprognostic (9.59e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (7.24e-4)" "unprognostic (1.17e-2)" "unprognostic (1.22e-1)" "unprognostic (1.15e-2)" "unprognostic (1.28e-3)" "unprognostic (1.08e-2)" "unprognostic (2.80e-3)" "unprognostic (8.73e-2)" "unprognostic (6.00e-2)" "unprognostic (7.06e-2)" "unprognostic (5.10e-2)" "unprognostic (1.95e-3)" "unprognostic (1.96e-1)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (6.71e-4)" "unprognostic (2.81e-1)" "unprognostic (2.60e-2)" "unprognostic (1.67e-1)" "unprognostic (5.70e-2)" "unprognostic (9.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.12e-1)" "unprognostic (6.35e-2)" "unprognostic (2.77e-1)" CHMP1B "C18orf2, CHMP1.5, Vps46B" ENSG00000255112 "Charged multivesicular body protein 1B" Q7LBR1 18 11851413-11854444 "Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "skeletal muscle: 344.7" "Cell type enhanced" "Detected in some" "cDC: 2.8;Conjunctival goblet cells: 2.9;Endometrial secretory cells: 2.3;Enterocytes: 2.7;Epididymal efferent duct absorptive cells: 2.5;Melanocytes: 2.3;Ocular epithelial cells: 2.7;Parietal cells: 3.5;Suprabasal keratinocytes: 3.9" "Cell type enhanced" "Detected in some" "Suprabasal cells: 3.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 1523987.5;Skeletal myofibers: 2359926.2" "Low tissue specificity" "Detected in all" "HPA061997, HPA062896" Supported Approved Nucleoplasm,Midbody Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 82: Dendritic cells - Antigen presentation" 25 "Nucleoplasm, Midbody" "HPA061997: , HPA062896: " "unprognostic (1.50e-2)" "unprognostic (3.32e-1)" "unprognostic (9.47e-2)" "unprognostic (2.97e-1)" "unprognostic (1.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.82e-1)" "unprognostic (4.26e-3)" "unprognostic (3.33e-3)" "unprognostic (2.74e-1)" "validated prognostic favorable (1.24e-8)" "validated prognostic favorable (7.60e-4)" "unprognostic (3.22e-2)" "unprognostic (9.79e-2)" "unprognostic (1.06e-1)" "unprognostic (3.29e-2)" "unprognostic (6.01e-3)" "unprognostic (2.27e-1)" "unprognostic (1.82e-1)" "unprognostic (1.95e-1)" "unprognostic (1.58e-2)" "unprognostic (7.96e-3)" "unprognostic (5.40e-2)" "unprognostic (1.53e-1)" "unprognostic (9.93e-2)" "unprognostic (4.12e-2)" "unprognostic (2.48e-1)" "unprognostic (1.76e-2)" "unprognostic (4.28e-1)" "unprognostic (1.90e-3)" "unprognostic (2.77e-1)" CHMP4C "MGC22825, Shax3, VPS32C" ENSG00000164695 "Charged multivesicular body protein 4C" Q96CF2 8 81732448-81759515 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 39.4" "Cell type enhanced" "Detected in many" "Enterocytes: 86.4;Esophageal apical cells: 308.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 308.8" "Group enriched" "Detected in some" 11 "choroid plexus epithelial cell: 4.3;endothelial cell: 6.8;vascular associated smooth muscle cell: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.9" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Somatotropes, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 3020587.6;Pancreas epithelial cells: 2890742.2" "Tissue enhanced" "Detected in many" "pancreas: 3059220.4" "HPA023763, HPA023799" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 40: Non-specific - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 18 "Microtubules, Cytokinetic bridge" "HPA023763: , HPA023799: " "unprognostic (2.26e-1)" "unprognostic (3.93e-2)" "unprognostic (4.02e-2)" "potential prognostic unfavorable (4.58e-6)" "unprognostic (4.50e-2)" "unprognostic (1.40e-2)" "unprognostic (9.45e-2)" "potential prognostic unfavorable (3.90e-4)" "potential prognostic favorable (2.20e-6)" "unprognostic (2.20e-3)" "unprognostic (7.87e-3)" "unprognostic (3.48e-2)" "unprognostic (1.11e-3)" "unprognostic (2.66e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (4.16e-2)" "unprognostic (2.07e-2)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (1.05e-2)" "unprognostic (7.51e-3)" "unprognostic (4.59e-2)" "unprognostic (5.61e-2)" "unprognostic (1.35e-1)" "unprognostic (2.73e-3)" "unprognostic (2.18e-1)" "unprognostic (3.61e-1)" "unprognostic (4.70e-1)" CHMP5 "C9orf83, CGI-34, HSPC177, SNF7DC2, Vps60" ENSG00000086065 "Charged multivesicular body protein 5" Q9NZZ3 9 33264879-33282070 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 371.8;Esophageal apical cells: 1078.0" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1078.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "CAB033874, HPA042883, HPA056437" Enhanced Supported Microtubules,Midbody,Cytosol Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 29 "Microtubules, Cytosol" Midbody "CAB033874: , HPA042883: , HPA056437: " "unprognostic (4.39e-2)" "unprognostic (6.50e-2)" "unprognostic (6.22e-3)" "unprognostic (2.66e-1)" "unprognostic (2.25e-1)" "unprognostic (3.13e-2)" "unprognostic (2.76e-1)" "unprognostic (2.73e-1)" "unprognostic (9.04e-2)" "unprognostic (1.97e-1)" "potential prognostic favorable (2.58e-9)" "unprognostic (3.04e-2)" "unprognostic (8.51e-3)" "unprognostic (1.22e-2)" "unprognostic (3.40e-2)" "unprognostic (1.82e-2)" "unprognostic (3.29e-2)" "unprognostic (6.35e-2)" "unprognostic (7.55e-2)" "unprognostic (9.26e-2)" "unprognostic (1.18e-3)" "unprognostic (4.99e-2)" "unprognostic (4.04e-2)" "unprognostic (4.71e-2)" "unprognostic (3.08e-1)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.65e-2)" "unprognostic (5.53e-1)" "unprognostic (3.68e-1)" "unprognostic (4.84e-1)" CHP2 ENSG00000166869 "Calcineurin like EF-hand protein 2" O43745 16 23755026-23758935 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 16 "intestine: 286.9;skin 1: 141.2" "Cell type enhanced" "Detected in some" "Colonocytes: 320.5;Enteric stem cells: 136.1;Enteric transient amplifying cells: 234.6;Enterocytes: 581.6;Goblet cells: 53.5;Paneth cells: 92.8;Respiratory secretory cells: 72.1" "Cell type enhanced" "Detected in many" "Enterocytes: 581.6;Proliferating cells: 234.6;Stem cells: 136.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 20.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 8.6;Bladder cancer: 6.8" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Keratinocytes: 430262.3" "Group enriched" "Detected in some" "intestine: 3664379.2;kidney: 3361698.8" "HPA055198, CAB072806" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 7 Nucleoplasm "Nucleoli, Cytosol" "CAB072806: , HPA055198: " "unprognostic (2.47e-1)" "unprognostic (9.90e-2)" "unprognostic (1.47e-2)" "unprognostic (7.13e-2)" "unprognostic (5.80e-2)" "unprognostic (8.53e-2)" "unprognostic (2.54e-1)" "unprognostic (2.34e-1)" "unprognostic (3.56e-2)" "unprognostic (3.32e-1)" "unprognostic (5.09e-1)" "unprognostic (1.39e-2)" "unprognostic (1.36e-2)" "unprognostic (4.33e-2)" "unprognostic (3.06e-3)" "potential prognostic unfavorable (6.00e-5)" "unprognostic (4.23e-2)" "unprognostic (1.71e-2)" "unprognostic (6.54e-3)" CHPF2 "ChSy-3, CSGlcA-T, KIAA1402" ENSG00000033100 "Chondroitin polymerizing factor 2" Q9P2E5 7 151232483-151240979 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 128.9;Epicardial cells: 72.8" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 72.8;Myocytes: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 5159184.8" "Group enriched" "Detected in some" 22547 "bone marrow: 1989701.0;intestine: 3510846.9;lymphoid tissue: 1263561.4" HPA020992 Approved Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nucleoplasm, Cytosol" "HPA020992: " "unprognostic (2.79e-1)" "unprognostic (9.03e-2)" "unprognostic (1.56e-2)" "potential prognostic unfavorable (3.41e-5)" "unprognostic (1.67e-1)" "unprognostic (7.37e-3)" "unprognostic (2.96e-3)" "unprognostic (3.95e-1)" "unprognostic (1.21e-2)" "unprognostic (2.19e-2)" "validated prognostic unfavorable (2.53e-4)" "validated prognostic unfavorable (8.80e-4)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (7.36e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.70e-2)" "unprognostic (1.29e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (7.67e-4)" "unprognostic (2.12e-1)" "unprognostic (2.88e-1)" "unprognostic (1.01e-1)" "unprognostic (1.66e-1)" "unprognostic (3.60e-2)" "unprognostic (1.94e-1)" "unprognostic (2.33e-1)" "unprognostic (9.88e-2)" "unprognostic (6.45e-2)" CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 469.0;Brain inhibitory neurons: 475.5;Gastric chief cells: 458.7;Granulosa cells: 429.8;Hematopoietic stem cells: 698.7;Lacrimal acinar cells: 585.2;Mucous neck cells: 597.4;Pancreatic acinar cells: 983.9;Salivary acinar cells: 2061.3;Salivary myoepithelial cells: 1305.7;Smooth muscle cells: 548.1" "Cell type enhanced" "Detected in many" "Acinar cells: 2061.3;Secretory gland support: 1305.7;Stem cells: 698.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 8.4" "Heart muscle - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 1147 "Granulosa cells: 113816.6;Large ducts: 82207.9;Pancreas epithelial cells: 148625.2;Pancreatic islets: 114178.8" "Tissue enriched" "Detected in some" "Stomach: 351531.4" "HPA024106, HPA048036" Approved Supported "Nucleoli,Vesicles,Plasma membrane,Primary cilium tip" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 56: Non-specific - Sensory perception" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Plasma membrane" "Nucleoli, Vesicles, Primary cilium tip" "HPA024106: , HPA048036: " "unprognostic (2.47e-1)" "unprognostic (7.72e-2)" "unprognostic (2.81e-1)" "unprognostic (9.58e-2)" "unprognostic (3.20e-1)" "unprognostic (1.46e-2)" "unprognostic (8.47e-2)" "unprognostic (3.94e-2)" "validated prognostic favorable (2.76e-8)" "validated prognostic favorable (8.41e-4)" "unprognostic (4.06e-1)" "unprognostic (6.82e-2)" "unprognostic (1.99e-2)" "unprognostic (9.97e-2)" "unprognostic (9.67e-2)" "unprognostic (6.00e-2)" "unprognostic (3.09e-1)" "unprognostic (2.29e-1)" "unprognostic (5.62e-2)" "unprognostic (2.44e-1)" "unprognostic (3.08e-2)" "unprognostic (1.16e-3)" CHRM4 ENSG00000180720 "Cholinergic receptor muscarinic 4" P08173 11 46383789-46391776 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.6;intestine: 5.8;lymphoid tissue: 14.4" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 2.5;Goblet cells: 14.8;Late primary spermatocytes: 8.0;Late spermatids: 10.0;Neuroendocrine cells: 3.5;Pancreatic islet cells: 5.8" "Cell type enhanced" "Detected in some" "Goblet cells: 14.8;Neuronal cells: 6.2;Pancreatic islet cells: 5.8;Spermatogenic cell types: 10.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in many" "basal ganglia: 44.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 22.1" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "cerebral cortex: 27280.9" "CAB022444, HPA072083" Enhanced Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" "Nucleoplasm, Plasma membrane, Primary cilium, Primary cilium tip" "CAB022444: , HPA072083: " "unprognostic (2.48e-1)" "unprognostic (4.43e-2)" "unprognostic (1.10e-2)" CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "prostate: 27.3" "Group enriched" "Detected in some" 6 "Epicardial cells: 22.7;Epididymal efferent duct absorptive cells: 19.6;Platelets: 38.0;Prostatic glandular cells: 34.5;Retinal amacrine cells: 52.8" "Group enriched" "Detected in some" 11 "Barrier epithelial cells: 22.7;Ductal cells: 19.6;Glandular cells: 34.5;Neuronal cells: 52.8;Platelets: 38.0" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 18.9;CGE interneuron: 27.8;thalamic excitatory: 26.3" "Cancer enriched" "Detected in single" 200 "Prostate Adenocarcinoma (TCGA): 51.0" "Region enhanced" "Detected in all" "thalamus: 157.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 36 "prostate cancer: 26.6" "Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 4.9" "Cell type enriched" "Detected in single" 267 "Capillaries: 26664.3" "Not detected" "Not detected" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (2.40e-1)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "adrenal gland: 37.1;lymphoid tissue: 61.2;retina: 49.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 117.0;Cone photoreceptor cells: 159.4;Oocytes: 32.2;Retinal pigment epithelial cells: 503.0" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 117.0;Neuronal cells: 159.4;Pigment cells: 503.0" "Group enriched" "Detected in some" 8 "cerebellar inhibitory: 55.5;midbrain-derived inhibitory: 49.0" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 20 "Neuroblastoma: 170.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA029430 Enhanced Approved "Nuclear speckles,Plasma membrane,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 "Nuclear speckles, Plasma membrane" "Primary cilium tip, Primary cilium transition zone, Basal body, Cytosol" "HPA029430: " "unprognostic (2.28e-1)" "unprognostic (4.23e-2)" "unprognostic (2.44e-1)" "unprognostic (3.19e-2)" "unprognostic (2.23e-1)" "unprognostic (2.20e-1)" "unprognostic (1.65e-2)" "unprognostic (2.25e-1)" "unprognostic (2.63e-3)" "unprognostic (3.56e-1)" CHST1 "C6ST, KSGal6ST" ENSG00000175264 "Carbohydrate sulfotransferase 1" O43916 11 45647689-45665622 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Astrocytes: 61.0;Bergmann glia: 22.7;Brain excitatory neurons: 25.7;Early spermatids: 66.0;Lacrimal acinar cells: 67.0;Late primary spermatocytes: 211.1;Other brain neurons: 24.4;Podocytes: 24.8;Salivary acinar cells: 22.6" "Cell type enhanced" "Detected in many" "Acinar cells: 67.0;Adrenal endocrine cells: 42.5;Glial cells: 61.0;Spermatogenic cell types: 211.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 147752.0;Neurons: 258229.8" "Tissue enriched" "Detected in single" 2245 "cerebral cortex: 224469.6" "HPA060313, HPA072592" Approved Nucleoli,Mitochondria "Intracellular and membrane" Enzyme NA NA 17000 "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Mitochondria Nucleoli "HPA060313: , HPA072592: " "unprognostic (1.96e-1)" "unprognostic (2.05e-3)" "unprognostic (2.27e-1)" "unprognostic (8.65e-2)" "unprognostic (2.50e-3)" "unprognostic (9.90e-2)" "unprognostic (4.39e-2)" "unprognostic (2.20e-1)" "unprognostic (3.20e-1)" "unprognostic (8.70e-2)" "unprognostic (5.50e-2)" "unprognostic (4.43e-1)" "potential prognostic unfavorable (1.62e-4)" "unprognostic (1.43e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (6.39e-5)" "unprognostic (6.55e-2)" "unprognostic (1.35e-1)" "unprognostic (9.77e-2)" "unprognostic (2.85e-1)" "unprognostic (1.02e-1)" "unprognostic (1.62e-1)" "unprognostic (1.94e-2)" "unprognostic (2.12e-1)" "unprognostic (2.37e-1)" "unprognostic (7.86e-3)" "unprognostic (2.71e-1)" "unprognostic (1.46e-1)" "unprognostic (1.41e-1)" CHST10 HNK-1ST ENSG00000115526 "Carbohydrate sulfotransferase 10" O43529 2 100391860-100417668 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Carbohydrate metabolism, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 29.2;Bergmann glia: 18.9;Pituicytes/FSCs: 24.9" "Cell type enhanced" "Detected in many" "Glial cells: 29.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 39.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 3890654.3" "Tissue enriched" "Detected in single" 865 "intestine: 86458.1" "HPA012884, HPA051545" Approved Approved Cytosol NA NA 600000 "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 6 Cytosol "HPA012884: , HPA051545: " "unprognostic (1.63e-2)" "unprognostic (3.44e-2)" "unprognostic (2.19e-1)" "unprognostic (5.21e-2)" "unprognostic (8.11e-3)" "unprognostic (1.46e-1)" "unprognostic (2.55e-1)" "unprognostic (7.07e-3)" "unprognostic (1.16e-1)" "unprognostic (1.45e-1)" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (1.86e-2)" "unprognostic (3.52e-2)" "unprognostic (2.26e-1)" "unprognostic (3.11e-1)" "unprognostic (1.93e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (7.50e-4)" "unprognostic (6.70e-2)" "unprognostic (2.74e-1)" "potential prognostic favorable (2.23e-4)" "unprognostic (6.64e-2)" "unprognostic (9.50e-2)" "unprognostic (4.58e-1)" "unprognostic (1.17e-1)" "unprognostic (8.06e-2)" "unprognostic (1.49e-2)" "unprognostic (1.35e-1)" "unprognostic (5.21e-2)" "unprognostic (5.23e-2)" CHST2 C6ST ENSG00000175040 "Carbohydrate sulfotransferase 2" Q9Y4C5 3 143119771-143124014 "Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Inflammatory response" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.8" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 67.0;Epididymal clear cells: 59.2;Müller glia: 96.4;NK-cells: 39.8;Pericytes: 32.0;Pituicytes/FSCs: 24.6;Plasma cells: 65.7" "Cell type enhanced" "Detected in many" "Glial cells: 96.4;Plasma cells: 65.7;Reproductive supporting cells: 59.2;Stromal cells: 67.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.3;NK-cell: 4.9;non-classical monocyte: 11.4" "Group enriched" "Detected in many" 5 "monocytes: 11.4;NK-cells: 4.9" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 3324118.6;Capillaries: 4761290.9;Pancreatic islets: 7190118.5" "Not detected" "Not detected" HPA013620 Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 44: Plasma cells - Antibody production & secretion" "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA013620: " "unprognostic (3.22e-1)" "unprognostic (3.40e-2)" "unprognostic (9.34e-2)" "unprognostic (3.89e-1)" "unprognostic (7.60e-2)" "unprognostic (2.23e-1)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (2.56e-1)" "unprognostic (4.04e-1)" "unprognostic (6.54e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-2)" "unprognostic (3.82e-2)" "unprognostic (1.44e-1)" "unprognostic (5.07e-2)" "unprognostic (5.26e-2)" "unprognostic (4.66e-2)" "unprognostic (5.88e-2)" "unprognostic (3.10e-2)" "unprognostic (2.43e-1)" "unprognostic (3.17e-3)" "unprognostic (2.08e-1)" "unprognostic (7.58e-2)" "unprognostic (1.72e-1)" "unprognostic (5.38e-2)" "unprognostic (2.66e-1)" "unprognostic (9.26e-2)" "unprognostic (1.27e-1)" "unprognostic (1.86e-2)" "unprognostic (1.59e-1)" CHUK "IkBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16" ENSG00000213341 "Component of inhibitor of nuclear factor kappa B kinase complex" O15111 10 100188300-100229596 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 84.0;Neutrophils: 140.6" "Cell type enhanced" "Detected in many" "Neutrophils: 140.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "intestine: 8816347.2" "HPA001402, CAB004240, CAB018564" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 120 Nucleoplasm Cytosol "CAB004240: , CAB018564: , HPA001402: " "unprognostic (6.24e-2)" "unprognostic (2.08e-3)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (3.12e-1)" "unprognostic (1.98e-1)" "potential prognostic favorable (2.79e-4)" "unprognostic (1.37e-1)" "unprognostic (9.46e-2)" "potential prognostic favorable (9.25e-9)" "unprognostic (2.79e-2)" "unprognostic (2.49e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.48e-2)" "unprognostic (1.40e-1)" "unprognostic (3.95e-1)" "unprognostic (2.12e-1)" "unprognostic (2.98e-2)" "potential prognostic unfavorable (3.35e-5)" "unprognostic (9.88e-2)" "unprognostic (4.98e-2)" "unprognostic (1.95e-1)" "unprognostic (1.69e-1)" "unprognostic (6.83e-2)" "unprognostic (2.41e-1)" "unprognostic (2.04e-1)" "unprognostic (2.26e-1)" "unprognostic (1.47e-3)" "unprognostic (1.33e-1)" CIAO2A "CIA2A, FAM96A, FLJ22875" ENSG00000166797 "Cytosolic iron-sulfur assembly component 2A" Q9H5X1 15 64072565-64093857 "Predicted intracellular proteins" "Chromosome partition" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 245.2" "Cell type enhanced" "Detected in all" "Hepatocytes: 268.9;Hofbauer cells: 221.1;Kupffer cells: 189.6;Parietal cells: 247.5" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 247.5;Hepatocytes: 268.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 3620381.8" "Tissue enriched" "Detected in all" "liver: 7761829.7" "HPA040459, HPA063729" Approved Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Other No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 113 "Nucleoplasm, Cytosol" "HPA040459: , HPA063729: " "unprognostic (2.49e-2)" "unprognostic (1.04e-1)" "unprognostic (1.37e-1)" "unprognostic (2.62e-1)" "unprognostic (6.48e-2)" "unprognostic (1.14e-2)" "unprognostic (3.74e-2)" "unprognostic (3.64e-2)" "unprognostic (6.51e-3)" "potential prognostic favorable (1.59e-6)" "unprognostic (2.19e-2)" "unprognostic (3.13e-1)" "unprognostic (5.97e-3)" "unprognostic (4.79e-2)" "unprognostic (2.81e-1)" "unprognostic (8.52e-3)" "unprognostic (2.00e-1)" "unprognostic (2.59e-1)" "unprognostic (1.97e-1)" "unprognostic (2.67e-1)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (9.25e-4)" "unprognostic (8.39e-3)" "unprognostic (2.44e-1)" "unprognostic (4.26e-2)" "unprognostic (1.62e-1)" "unprognostic (1.96e-1)" "unprognostic (1.75e-1)" "unprognostic (1.45e-1)" CIAPIN1 CIAE2 ENSG00000005194 "Cytokine induced apoptosis inhibitor 1" Q6FI81 16 57428187-57447420 "Essential proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 117.9;Early primary spermatocytes: 155.2;Late primary spermatocytes: 356.4;Oocytes: 142.8;Syncytiotrophoblasts: 132.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 356.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA041350, HPA042182" Enhanced Supported Nucleoplasm,Mitochondria No No 20000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 17 Mitochondria Nucleoplasm "HPA041350: , HPA042182: " "unprognostic (3.30e-2)" "unprognostic (1.53e-3)" "unprognostic (2.97e-3)" "unprognostic (2.66e-2)" "unprognostic (4.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.02e-3)" "potential prognostic favorable (2.52e-4)" "potential prognostic unfavorable (4.22e-5)" "unprognostic (6.42e-2)" "potential prognostic favorable (2.31e-5)" "unprognostic (1.89e-1)" "potential prognostic favorable (2.23e-4)" "potential prognostic unfavorable (2.96e-6)" "unprognostic (3.31e-3)" "unprognostic (1.66e-2)" "unprognostic (1.36e-2)" "unprognostic (1.48e-1)" "unprognostic (2.51e-1)" "unprognostic (2.99e-2)" "unprognostic (1.76e-1)" "unprognostic (7.16e-2)" "unprognostic (1.45e-2)" "unprognostic (5.31e-2)" "unprognostic (2.13e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (2.35e-1)" "unprognostic (4.86e-2)" "unprognostic (9.04e-3)" "unprognostic (5.87e-2)" CIB2 "DFNB48, KIP2, USH1J" ENSG00000136425 "Calcium and integrin binding family member 2" O75838 15 78104606-78131535 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 46.8;lymphoid tissue: 44.7" "Cell type enriched" "Detected in many" 5 "Late spermatids: 501.2" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 501.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "plasmacytoid DC: 18.7" "Lineage enriched" "Detected in single" 48 "dendritic cells: 18.7" "Cancer enhanced" "Detected in all" "testis cancer: 45.5" "Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Keratinocytes: 5755582.4" "Not detected" "Not detected" HPA036697 Approved Uncertain "Nucleoplasm,Primary cilium transition zone,Centrosome,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 11: Neuronal - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 32 Nucleoplasm "Primary cilium transition zone, Centrosome, Cytosol" "HPA036697: " "unprognostic (2.25e-2)" "unprognostic (6.22e-3)" "unprognostic (1.88e-1)" "unprognostic (1.85e-2)" "unprognostic (9.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.86e-1)" "unprognostic (2.85e-1)" "unprognostic (9.20e-2)" "unprognostic (7.70e-2)" "unprognostic (5.68e-3)" "unprognostic (1.32e-1)" "unprognostic (1.69e-1)" "unprognostic (6.87e-3)" "unprognostic (1.29e-3)" "unprognostic (1.24e-3)" "unprognostic (2.87e-1)" "unprognostic (1.14e-1)" "unprognostic (6.60e-2)" "unprognostic (2.91e-2)" "unprognostic (4.53e-2)" "unprognostic (1.54e-1)" "unprognostic (6.54e-3)" "unprognostic (4.52e-2)" "unprognostic (3.02e-1)" "unprognostic (1.47e-1)" "unprognostic (4.36e-2)" "unprognostic (3.68e-2)" "unprognostic (4.07e-2)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" CIDEB ENSG00000136305 "Cell death inducing DFFA like effector b" Q9UHD4 14 24305187-24311430 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 175.5;liver: 448.3" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Enterocytes: 3.9;Ependymal cells: 4.7;Hepatocytes: 3.1;Innate lymphoid cells: 2.2;Microglia: 3.5;NK-cells: 1.7;Papillary tip epithelial cells: 1.8" "Cell type enhanced" "Detected in some" "Ciliated cells: 4.7;Enterocytes: 3.9;Glial cells: 3.5" "Cell type enhanced" "Detected in some" "ependymal cell: 6.6;leukocyte: 7.6" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 41.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Leukemia: 10.7;liver cancer: 11.1;Myeloma: 10.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Hepatocytes: 4002050.1" "Tissue enriched" "Detected in single" 15800 "liver: 1580003.5" "HPA001272, HPA059646" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 62 "Golgi apparatus, Vesicles" "HPA001272: , HPA059646: " "unprognostic (1.87e-2)" "unprognostic (3.54e-1)" "unprognostic (1.45e-1)" "unprognostic (5.93e-2)" "unprognostic (4.94e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (6.68e-2)" "unprognostic (2.73e-2)" "unprognostic (5.51e-2)" "unprognostic (2.75e-2)" "potential prognostic favorable (4.59e-5)" "unprognostic (1.26e-2)" "potential prognostic favorable (6.45e-4)" "unprognostic (1.53e-2)" "unprognostic (1.03e-3)" "unprognostic (1.04e-3)" "unprognostic (2.21e-3)" "unprognostic (1.92e-1)" "unprognostic (1.12e-2)" "unprognostic (6.54e-2)" "unprognostic (4.71e-1)" "unprognostic (2.07e-1)" "unprognostic (1.05e-2)" "unprognostic (2.59e-1)" "unprognostic (5.06e-2)" "unprognostic (3.13e-1)" "unprognostic (4.57e-2)" "unprognostic (1.09e-1)" "unprognostic (2.58e-1)" "unprognostic (5.13e-2)" CILK1 "ICK, KIAA0936, LCK2, MGC46090, MRK" ENSG00000112144 "Ciliogenesis associated kinase 1" Q9UPZ9 6 53001279-53061824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 117.2" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 137.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4738 "Fallopian tube cells: 473837.2" "Tissue enriched" "Detected in single" 98 "kidney: 9750.3" HPA001113 Approved Approved "Golgi apparatus,Vesicles,Primary cilium,Primary cilium tip" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 18: Adrenal cortex cells - Steroidogensis" 15 "Golgi apparatus, Vesicles" "Primary cilium, Primary cilium tip" "HPA001113: " "unprognostic (1.95e-1)" "unprognostic (3.25e-3)" "unprognostic (3.67e-1)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (2.04e-1)" "unprognostic (7.99e-3)" "unprognostic (8.84e-2)" "unprognostic (2.46e-2)" "validated prognostic favorable (2.15e-5)" "validated prognostic favorable (1.58e-7)" "unprognostic (5.25e-2)" "unprognostic (3.09e-1)" "unprognostic (8.34e-2)" "unprognostic (1.14e-1)" "unprognostic (1.73e-3)" "unprognostic (3.58e-3)" "unprognostic (9.98e-2)" "potential prognostic unfavorable (8.86e-4)" "unprognostic (2.36e-2)" "unprognostic (1.17e-3)" "unprognostic (9.07e-2)" "unprognostic (2.04e-2)" "unprognostic (2.27e-2)" "unprognostic (1.66e-2)" "unprognostic (2.49e-1)" "unprognostic (2.30e-1)" "unprognostic (6.78e-2)" "unprognostic (4.77e-2)" CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "DNA damage" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 48.6;Erythrocyte progenitors: 68.7;Late primary spermatocytes: 110.3;Megakaryocyte progenitors: 53.7;Monocyte progenitors: 119.1;Neutrophil progenitors: 87.3" "Cell type enhanced" "Detected in many" "Erythrocytes: 68.7;Mononuclear phagocytes: 119.1;Neutrophils: 87.3;Spermatogenic cell types: 110.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Granulosa cells: 1593707.2;Large ducts: 2233887.1" "Group enriched" "Detected in some" "bone marrow: 25016605.3;lymphoid tissue: 35468575.7" HPA039570 Approved Approved "Plasma membrane,Centrosome,Basal body,Cytosol" NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Non-specific - Cell proliferation" 19 Cytosol "Plasma membrane, Centrosome, Basal body" "HPA039570: " "unprognostic (1.27e-1)" "unprognostic (1.07e-1)" "unprognostic (8.12e-2)" "unprognostic (1.43e-2)" "unprognostic (9.53e-3)" "unprognostic (1.93e-1)" "unprognostic (1.37e-2)" "unprognostic (1.08e-1)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "potential prognostic unfavorable (6.14e-5)" "unprognostic (1.75e-3)" "unprognostic (8.03e-3)" "unprognostic (2.20e-1)" "unprognostic (1.37e-1)" "unprognostic (1.85e-3)" "validated prognostic unfavorable (7.37e-4)" "validated prognostic unfavorable (2.50e-4)" "unprognostic (6.58e-2)" "unprognostic (1.15e-1)" "unprognostic (8.22e-2)" "unprognostic (1.38e-2)" "unprognostic (1.38e-1)" "unprognostic (1.02e-3)" CISH "CIS, CIS-1, G18, SOCS" ENSG00000114737 "Cytokine inducible SH2 containing protein" Q9NSE2 3 50606489-50611774 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 59.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 32.7;Alveolar cells type 2: 81.9;Breast lactating cells: 79.3;Epididymal efferent duct absorptive cells: 46.1;Fallopian tube ciliated cells: 31.9;Transitional alveolar cells: 41.3" "Cell type enhanced" "Detected in many" "Alveolar cells: 81.9;Secretory cells: 79.3" "Cell type enriched" "Detected in some" 13 "leukocyte: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 6 "breast cancer: 18.6;Leukemia: 48.5;lymphoma: 13.5" "Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034039, HPA040812" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 11: T-cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 8: Immune cells - Immune response" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 81: Alveolar cells - Lung function" 14 Microtubules "Cytokinetic bridge" "CAB034039: , HPA040812: " "unprognostic (9.68e-3)" "unprognostic (4.32e-3)" "unprognostic (2.35e-1)" "unprognostic (3.56e-2)" "unprognostic (2.45e-2)" "unprognostic (5.85e-2)" "unprognostic (5.93e-2)" "unprognostic (6.08e-2)" "unprognostic (1.45e-1)" "unprognostic (3.29e-1)" "potential prognostic favorable (2.27e-7)" "unprognostic (3.58e-2)" "potential prognostic favorable (3.75e-4)" "unprognostic (6.33e-3)" "unprognostic (8.45e-2)" "potential prognostic favorable (3.92e-4)" "unprognostic (1.88e-1)" "unprognostic (6.36e-3)" "unprognostic (1.13e-2)" "unprognostic (2.60e-1)" "unprognostic (6.57e-2)" "unprognostic (1.02e-2)" "unprognostic (5.41e-2)" "unprognostic (7.79e-2)" "unprognostic (5.56e-2)" "unprognostic (9.27e-2)" "unprognostic (1.68e-1)" "unprognostic (9.61e-2)" "unprognostic (2.61e-1)" "unprognostic (1.70e-1)" "unprognostic (6.41e-2)" CKAP2 "FLJ10749, LB1, se20-10, TMAP" ENSG00000136108 "Cytoskeleton associated protein 2" Q8WWK9 13 52455429-52476628 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 184.0;Erythrocyte progenitors: 127.6;Granulosa cells: 91.6;Late primary spermatocytes: 113.8;Megakaryocyte progenitors: 103.8;Monocyte progenitors: 141.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 127.6;Mononuclear phagocytes: 141.1;Spermatogenic cell types: 184.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 22933 "Granulosa cells: 2293329.6" "Tissue enriched" "Detected in single" 72 "bone marrow: 7179.2" "HPA008410, HPA027821" Enhanced Supported "Microtubules,Mitotic spindle,Primary cilium,Centrosome,Basal body" Yes Yes "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 28 "Microtubules, Mitotic spindle, Primary cilium" "Centrosome, Basal body" "HPA008410: , HPA027821: " "unprognostic (3.42e-2)" "unprognostic (2.16e-1)" "unprognostic (3.69e-2)" "unprognostic (5.54e-3)" "unprognostic (1.00e-1)" "unprognostic (1.64e-1)" "unprognostic (4.08e-2)" "unprognostic (6.77e-3)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.17e-3)" "unprognostic (5.95e-2)" "potential prognostic unfavorable (5.66e-4)" "validated prognostic unfavorable (6.25e-5)" "validated prognostic unfavorable (5.22e-5)" "unprognostic (4.13e-3)" "unprognostic (1.50e-2)" "unprognostic (3.54e-1)" "unprognostic (9.80e-2)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (2.01e-1)" "unprognostic (5.02e-2)" "unprognostic (1.78e-3)" "unprognostic (8.11e-3)" "unprognostic (2.78e-2)" "unprognostic (1.90e-2)" "unprognostic (2.75e-2)" "unprognostic (7.66e-2)" "unprognostic (9.37e-2)" "unprognostic (9.17e-2)" "unprognostic (1.09e-1)" CKAP2L "FLJ40629, radmis" ENSG00000169607 "Cytoskeleton associated protein 2 like" Q8IYA6 2 112736349-112764664 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.4;lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 43.9;Early primary spermatocytes: 42.7;Early spermatids: 27.4;Endometrial luminal cells: 26.1;Erythrocyte progenitors: 55.5;Esophageal basal cells: 31.2;Late primary spermatocytes: 24.5;Megakaryocyte progenitors: 130.0;Megakaryocytes: 61.8;Monocyte progenitors: 66.2;Neutrophil progenitors: 32.0;Undifferentiated spermatogonia: 43.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 55.5;Megakaryocytes: 130.0;Mononuclear phagocytes: 66.2;Spermatogenic cell types: 43.9" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 892 "Granulosa cells: 89229.3" "Tissue enriched" "Detected in single" 178 "heart muscle: 17794.9" "HPA039407, HPA040057, HPA070737" Uncertain Supported "Microtubules,Mitotic spindle,Primary cilium,Cytosol" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Non-specific - Cell proliferation" 5 Microtubules "Mitotic spindle, Primary cilium, Cytosol" "HPA039407: , HPA040057: , HPA070737: " "potential prognostic unfavorable (9.98e-4)" "unprognostic (3.10e-1)" "unprognostic (2.47e-1)" "unprognostic (9.76e-2)" "unprognostic (1.15e-2)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (4.53e-3)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (8.82e-4)" "validated prognostic unfavorable (9.06e-5)" "validated prognostic unfavorable (2.29e-6)" "validated prognostic unfavorable (3.57e-5)" "validated prognostic unfavorable (4.81e-5)" "unprognostic (1.97e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (2.31e-1)" "validated prognostic unfavorable (2.18e-5)" "validated prognostic unfavorable (1.08e-4)" "unprognostic (1.53e-1)" "unprognostic (3.79e-1)" "unprognostic (6.45e-3)" "unprognostic (8.83e-2)" "unprognostic (8.82e-2)" "unprognostic (1.23e-3)" CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in all" "cerebral cortex: 134123828.1" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Mitotic spindle,Primary cilium,Centrosome,Basal body" Yes Yes 160000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 38 "Centrosome, Basal body" "Nucleoli, Nucleoli rim, Plasma membrane, Mitotic spindle, Primary cilium" "HPA039377: , HPA040375: " "unprognostic (6.22e-2)" "unprognostic (6.92e-3)" "unprognostic (2.42e-1)" "unprognostic (2.84e-3)" "unprognostic (2.16e-1)" "unprognostic (1.25e-1)" "unprognostic (3.83e-1)" "unprognostic (1.38e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (2.79e-7)" "unprognostic (4.39e-3)" "unprognostic (1.58e-1)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (6.48e-7)" "unprognostic (5.66e-3)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (6.42e-5)" "unprognostic (2.33e-1)" "unprognostic (2.45e-1)" "unprognostic (2.62e-1)" "unprognostic (2.27e-1)" "unprognostic (1.38e-2)" "unprognostic (1.38e-2)" "unprognostic (7.63e-2)" "unprognostic (8.18e-3)" "unprognostic (2.22e-2)" "unprognostic (2.87e-1)" "unprognostic (3.99e-1)" "unprognostic (6.51e-2)" "unprognostic (6.30e-2)" "unprognostic (7.41e-2)" CKB CKBB ENSG00000166165 "Creatine kinase B" P12277 14 103519667-103522833 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1487.2;intestine: 1025.7" "Cell type enhanced" "Detected in many" "Colonocytes: 6345.6;Cone photoreceptor cells: 2246.1;Fallopian tube ciliated cells: 1301.0;Müller glia: 2585.4;Parietal cells: 5522.9;Retinal bipolar cells: 1423.8;Retinal horizontal cells: 2350.0;Rod photoreceptor cells: 1636.6;Smooth muscle cells: 1464.7" "Cell type enhanced" "Detected in all" "Enterocytes: 6345.6;Gastric glandular cells: 5522.9;Glial cells: 2585.4;Neuronal cells: 2350.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 1264.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "non-classical monocyte: 292.6" "Lineage enriched" "Detected in many" 18 "monocytes: 292.6" "Cancer enhanced" "Detected in all" "prostate cancer: 769.0" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 1313710703.5;Microglia and Neuropil: 1221847046.7" "Tissue enhanced" "Detected in all" "cerebral cortex: 1891701315.7" "HPA001254, CAB047313" Enhanced Supported Cytosol No No 22000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 32 Cytosol "CAB047313: , HPA001254: " "unprognostic (5.35e-2)" "unprognostic (4.14e-2)" "unprognostic (3.77e-1)" "unprognostic (4.27e-3)" "unprognostic (3.61e-2)" "potential prognostic favorable (7.02e-5)" "unprognostic (9.28e-2)" "unprognostic (1.14e-1)" "unprognostic (2.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.83e-3)" "unprognostic (2.72e-1)" "potential prognostic favorable (1.36e-6)" "unprognostic (8.86e-2)" "unprognostic (2.05e-1)" "unprognostic (1.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.67e-2)" "unprognostic (2.06e-2)" "unprognostic (1.52e-1)" "unprognostic (3.62e-1)" "unprognostic (2.03e-2)" "unprognostic (3.82e-2)" "unprognostic (3.69e-2)" "unprognostic (2.11e-3)" "unprognostic (1.95e-2)" "unprognostic (1.79e-1)" "unprognostic (4.36e-2)" "unprognostic (1.20e-1)" "unprognostic (1.45e-3)" "unprognostic (1.25e-1)" CKS1B "CKS1, ckshs1" ENSG00000173207 "CDC28 protein kinase regulatory subunit 1B" P61024 1 154974653-154979251 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 147.4;Enteric transient amplifying cells: 170.4;Extravillous trophoblasts: 525.8;Gastric progenitor cells: 434.5;Migrating cytotrophoblasts: 265.9;Oocytes: 331.6" "Cell type enhanced" "Detected in all" "Oocytes: 331.6;Proliferating cells: 434.5;Trophoblast cells: 525.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Oocytes: 73215.8" "Tissue enriched" "Detected in single" 3081 "bone marrow: 308065.9" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 78 "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: , HPA030762: " "unprognostic (2.84e-3)" "unprognostic (4.85e-2)" "unprognostic (9.84e-3)" "unprognostic (2.74e-2)" "unprognostic (2.44e-1)" "unprognostic (3.31e-2)" "unprognostic (4.31e-1)" "unprognostic (3.40e-3)" "unprognostic (3.59e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (1.45e-6)" "potential prognostic unfavorable (3.42e-6)" "unprognostic (2.04e-3)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (4.16e-3)" "unprognostic (2.79e-2)" "unprognostic (3.60e-2)" "unprognostic (1.20e-1)" "unprognostic (7.05e-2)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (2.16e-1)" "unprognostic (2.66e-1)" "unprognostic (2.39e-1)" "unprognostic (3.88e-1)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (2.81e-1)" "unprognostic (8.02e-3)" "unprognostic (1.93e-2)" CKS2 ENSG00000123975 "CDC28 protein kinase regulatory subunit 2" P33552 9 89311195-89316703 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 167.0;testis: 175.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 609.6;Early primary spermatocytes: 577.8;Extravillous trophoblasts: 422.1;Gastric progenitor cells: 480.6;Granulosa cells: 440.4;Late primary spermatocytes: 1009.5;Migrating cytotrophoblasts: 346.0;Oocytes: 741.4;Undifferentiated spermatogonia: 337.8" "Cell type enhanced" "Detected in many" "Oocytes: 741.4;Spermatogenic cell types: 1009.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 188.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 2903 "Granulosa cells: 389024.3;Oocytes: 191525.9" "Tissue enriched" "Detected in some" "bone marrow: 8024136.2" "HPA003424, HPA030762" Approved Approved Nucleoplasm,Vesicles,Mitochondria,Cytosol NA Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 26 "Mitochondria, Cytosol" "Nucleoplasm, Vesicles" "HPA003424: , HPA030762: " "unprognostic (4.67e-3)" "unprognostic (8.75e-3)" "unprognostic (2.48e-2)" "unprognostic (2.46e-1)" "unprognostic (7.68e-2)" "unprognostic (1.04e-1)" "unprognostic (4.81e-3)" "unprognostic (3.93e-2)" "unprognostic (4.48e-2)" "unprognostic (1.97e-3)" "unprognostic (1.05e-3)" "potential prognostic unfavorable (7.50e-4)" "potential prognostic unfavorable (1.69e-9)" "validated prognostic unfavorable (3.86e-6)" "validated prognostic unfavorable (4.78e-7)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (2.95e-2)" "unprognostic (8.45e-2)" "unprognostic (4.77e-2)" "unprognostic (8.03e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (4.19e-3)" "unprognostic (2.65e-3)" "unprognostic (8.55e-2)" "unprognostic (9.99e-2)" "unprognostic (2.85e-2)" "unprognostic (1.41e-2)" "unprognostic (2.83e-1)" "unprognostic (2.13e-1)" "unprognostic (1.04e-1)" CLCN6 "CLC-6, KIAA0046" ENSG00000011021 "Chloride voltage-gated channel 6" P51797 1 11806096-11848079 "Disease related genes, Plasma proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 133.8" "Cell type enhanced" "Detected in many" "Myocytes: 133.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 16369539.4" "Tissue enriched" "Detected in some" "cerebral cortex: 5372723.4" HPA032097 Approved Uncertain "Plasma membrane,Cytosol" No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Plasma membrane, Cytosol" "HPA032097: " "unprognostic (1.07e-2)" "unprognostic (1.68e-1)" "unprognostic (1.45e-1)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" "unprognostic (5.70e-2)" "unprognostic (2.30e-1)" "unprognostic (3.36e-2)" "unprognostic (6.93e-2)" "unprognostic (1.67e-1)" "validated prognostic favorable (5.98e-5)" "validated prognostic favorable (3.86e-4)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (3.11e-5)" "unprognostic (5.40e-2)" "unprognostic (1.26e-2)" "unprognostic (2.16e-1)" "unprognostic (2.52e-2)" "unprognostic (3.49e-1)" "unprognostic (3.12e-2)" "unprognostic (2.87e-1)" "unprognostic (1.11e-2)" "unprognostic (9.16e-3)" "unprognostic (2.21e-1)" "unprognostic (2.87e-1)" "potential prognostic favorable (3.60e-5)" "unprognostic (1.48e-1)" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (4.51e-2)" "unprognostic (3.29e-1)" CLDN18 SFTPJ ENSG00000066405 "Claudin 18" P56856 3 137998735-138033655 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 51 "lung: 237.8;stomach 1: 684.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 871.0;Alveolar cells type 2: 488.9;Foveolar cells: 2380.6;Gastric chief cells: 400.8;Gastric progenitor cells: 380.7;Mucous neck cells: 609.5;Parietal cells: 753.1;Transitional alveolar cells: 313.5" "Group enriched" "Detected in many" 4 "Alveolar cells: 871.0;Gastric glandular cells: 2380.6" "Cell type enhanced" "Detected in many" "ependymal cell: 12.9" "Group enriched" "Detected in some" 7 "Pancreatic Adenocarcinoma (TCGA): 178.0;Stomach Adenocarcinoma (TCGA): 285.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 17.9;pancreatic cancer: 12.4" "Lung - Alveolar cells type 1, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 93503 "Alveolar cell types: 9350271.1" "Tissue enriched" "Detected in some" "lung: 7482438.2" "CAB013010, CAB013243, HPA018446" Enhanced Approved "Cell Junctions" NA NA "Cluster 60: Stomach - Digestion" "Cluster 17: Choroid plexus - Cilium" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 2 "Cell Junctions" "CAB013010: , CAB013243: , HPA018446: " "unprognostic (1.72e-1)" "unprognostic (3.78e-1)" "unprognostic (2.97e-2)" "unprognostic (1.93e-3)" "unprognostic (1.00e-1)" "unprognostic (1.06e-2)" "unprognostic (3.35e-1)" "unprognostic (3.21e-2)" "unprognostic (1.55e-3)" "unprognostic (1.84e-2)" "unprognostic (1.26e-1)" "unprognostic (2.42e-1)" CLDN19 ENSG00000164007 "Claudin 19" Q8N6F1 1 42733093-42740254 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 12.2;kidney: 42.4;placenta: 9.2" "Group enriched" "Detected in some" 4 "Extravillous trophoblasts: 360.7;Retinal pigment epithelial cells: 98.0" "Group enriched" "Detected in some" 8 "Pigment cells: 98.0;Trophoblast cells: 360.7" "Cell type enriched" "Detected in single" 11 "choroid plexus epithelial cell: 4.3" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.2" "Region enriched" "Detected in many" 14 "choroid plexus: 43.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.9;testis cancer: 3.2" "Breast - Breast myoepithelial cells, Kidney - Ascending Loop of Henle cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Region enhanced" "Detected in many" "olfactory bulb: 5.4" "Region enriched" "Detected in all" 5 "spinal cord: 89.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA014412 Supported "Plasma membrane" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" "Plasma membrane" "HPA014412: " "unprognostic (2.19e-1)" "unprognostic (1.94e-2)" "unprognostic (4.50e-2)" "unprognostic (1.98e-1)" "unprognostic (3.59e-2)" "unprognostic (1.19e-2)" "unprognostic (2.75e-1)" "unprognostic (1.85e-1)" "unprognostic (9.88e-2)" "unprognostic (2.05e-2)" CLDN2 ENSG00000165376 "Claudin 2" P57739 X 106900164-106930861 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 189.2;gallbladder: 95.3;kidney: 154.2;seminal vesicle: 85.1" "Cell type enriched" "Detected in some" 6 "Epididymal efferent duct absorptive cells: 351.7" "Cell type enriched" "Detected in many" 6 "Ductal cells: 351.7" "Cell type enriched" "Detected in some" 19 "choroid plexus epithelial cell: 70.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 221.1" "Region enriched" "Detected in many" 13 "choroid plexus: 243.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 127.7;Kidney cancer: 98.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells" "Group enriched" "Detected in many" 4 "basal ganglia: 4.5;hippocampal formation: 9.5;pons and medulla: 10.3;thalamus: 8.9" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Proximal tubules: 2821653.6" "Not detected" "Not detected" "CAB002609, HPA051548, HPA074528" Enhanced Supported "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 20 "Plasma membrane, Cell Junctions" "Nucleoplasm, Nucleoli, Vesicles" "CAB002609: , HPA051548: , HPA074528: " "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (3.34e-1)" "unprognostic (3.64e-1)" "potential prognostic favorable (8.01e-6)" "unprognostic (7.56e-3)" "unprognostic (9.58e-3)" "unprognostic (7.70e-2)" "unprognostic (8.67e-3)" "potential prognostic favorable (6.58e-5)" "unprognostic (8.02e-2)" "unprognostic (1.23e-2)" "unprognostic (1.78e-1)" "unprognostic (5.45e-2)" "unprognostic (1.43e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (2.09e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (2.00e-4)" "unprognostic (6.34e-2)" CLDN20 ENSG00000171217 "Claudin 20" P56880 6 155264013-155276548 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Cell type enhanced" "Detected in many" "Adipocytes: 21.4;Cardiomyocytes: 87.3;Epicardial cells: 25.0;Mast cells: 13.8;Myonuclei: 24.6;Retinal horizontal cells: 14.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 25.0;Myocytes: 87.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in single" "Lung Squamous Cell Carcinoma (TCGA): 1.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA073105 Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 40: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "Golgi apparatus, Plasma membrane" Cytosol "HPA073105: " "unprognostic (3.37e-1)" "unprognostic (3.52e-2)" "unprognostic (1.66e-2)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 408.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 590.8;Epicardial cells: 755.0;Extravillous trophoblasts: 629.5;Mesothelial cells: 588.3;Plasma cells: 613.3;Schwann cells: 1130.9;Smooth muscle cells: 835.4" "Cell type enhanced" "Detected in all" "Glial cells: 1130.9" "Cell type enhanced" "Detected in all" "endothelial cell: 719.9;oligodendrocyte: 290.2;vascular associated smooth muscle cell: 335.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.5;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glomeruli: 163104083.4;Proximal tubules: 296573444.1" "Low tissue specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome,Calyx,Connecting piece,Principal piece" NA NA 3800000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 7 "Plasma membrane, Centrosome" "Calyx, Connecting piece, Principal piece" "HPA008019: , HPA060804: " "unprognostic (2.90e-1)" "unprognostic (5.65e-2)" "unprognostic (1.58e-3)" "unprognostic (4.17e-3)" "unprognostic (2.82e-1)" "unprognostic (1.90e-1)" "unprognostic (9.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.86e-1)" "unprognostic (5.81e-3)" "potential prognostic favorable (2.33e-7)" "unprognostic (2.67e-2)" "potential prognostic favorable (4.05e-4)" "unprognostic (6.48e-3)" "unprognostic (3.78e-2)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (9.51e-3)" "unprognostic (1.82e-1)" "unprognostic (2.03e-3)" "unprognostic (1.65e-2)" "unprognostic (6.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.11e-1)" "unprognostic (1.25e-1)" "unprognostic (7.53e-2)" "unprognostic (3.16e-2)" "unprognostic (1.50e-3)" "unprognostic (3.98e-1)" "unprognostic (3.13e-3)" "unprognostic (1.43e-1)" CLK4 ENSG00000113240 "CDC like kinase 4" Q9HAZ1 5 178602664-178630615 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 355.3;Late spermatids: 773.4" "Cell type enriched" "Detected in all" 5 "Spermatogenic cell types: 773.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Large ducts: 149779.5;Neurons: 594950.5;T-cells: 300105.8" "Not detected" "Not detected" HPA043746 Approved Approved "Actin filaments" No No "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 11 "Actin filaments" "HPA043746: " "unprognostic (2.70e-2)" "unprognostic (3.33e-1)" "unprognostic (1.74e-1)" "unprognostic (6.55e-2)" "unprognostic (1.73e-1)" "unprognostic (5.73e-2)" "unprognostic (1.39e-1)" "unprognostic (3.85e-2)" "unprognostic (4.63e-1)" "unprognostic (1.92e-1)" "unprognostic (1.94e-3)" "potential prognostic favorable (9.38e-4)" "unprognostic (8.53e-2)" "unprognostic (6.18e-2)" "unprognostic (4.85e-2)" "unprognostic (1.82e-1)" "unprognostic (2.65e-1)" "unprognostic (1.99e-2)" "unprognostic (3.87e-2)" "unprognostic (8.36e-2)" "unprognostic (8.70e-2)" "unprognostic (3.82e-2)" "unprognostic (1.02e-3)" "unprognostic (3.21e-2)" "unprognostic (1.27e-1)" "unprognostic (3.17e-2)" "unprognostic (1.31e-1)" "unprognostic (7.70e-2)" "unprognostic (2.54e-1)" "unprognostic (2.24e-2)" "unprognostic (1.29e-1)" CLNS1A "CLCI, ICln" ENSG00000074201 "Chloride nucleotide-sensitive channel 1A" P54105 11 77514936-77637794 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 4724445.8" "Tissue enhanced" "Detected in all" "fallopian tube: 47872476.4" "CAB017840, HPA031707, HPA031708, HPA032045" Approved Supported "Nucleoplasm,Microtubules,Primary cilium,Cytosol,Connecting piece,Mid piece,Principal piece" No No 17000 "Cluster 13: Non-specific - Mitochondria" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 119 "Nucleoplasm, Cytosol" "Microtubules, Primary cilium, Connecting piece, Mid piece, Principal piece" "CAB017840: , HPA031707: , HPA031708: , HPA032045: " "unprognostic (8.18e-2)" "unprognostic (2.32e-1)" "unprognostic (1.25e-1)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (6.33e-2)" "unprognostic (3.44e-3)" "unprognostic (1.55e-2)" "unprognostic (1.86e-2)" "unprognostic (1.01e-2)" "potential prognostic favorable (7.03e-5)" "unprognostic (1.06e-1)" "unprognostic (1.47e-2)" "unprognostic (1.28e-2)" "unprognostic (8.27e-3)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (3.19e-1)" "unprognostic (4.69e-1)" "unprognostic (7.61e-2)" "unprognostic (4.55e-2)" "potential prognostic unfavorable (6.04e-5)" "unprognostic (6.95e-2)" "unprognostic (3.71e-2)" "unprognostic (3.60e-3)" "unprognostic (9.92e-2)" "unprognostic (3.16e-2)" "unprognostic (1.29e-1)" "unprognostic (1.73e-1)" "unprognostic (1.38e-1)" "unprognostic (1.86e-1)" CLP1 "hClp1, HEAB" ENSG00000172409 "Cleavage factor polyribonucleotide kinase subunit 1" Q92989 11 57648188-57661865 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, tRNA processing" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.5" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 47.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Macrophages, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 947924.2" HPA057770 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 20 Nucleoplasm Cytosol "HPA057770: " "unprognostic (1.37e-1)" "unprognostic (2.00e-1)" "unprognostic (3.44e-2)" "unprognostic (1.39e-1)" "unprognostic (3.09e-1)" "unprognostic (1.98e-2)" "unprognostic (8.88e-2)" "unprognostic (1.10e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (6.15e-4)" "potential prognostic favorable (4.52e-6)" "unprognostic (2.31e-2)" "unprognostic (2.82e-1)" "unprognostic (1.03e-2)" "unprognostic (9.22e-3)" "unprognostic (4.54e-2)" "unprognostic (1.06e-2)" "unprognostic (1.56e-1)" "unprognostic (4.09e-1)" "unprognostic (2.49e-1)" "unprognostic (9.14e-3)" "unprognostic (1.20e-1)" "unprognostic (1.08e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (3.67e-4)" "unprognostic (2.13e-2)" "unprognostic (5.66e-2)" "unprognostic (1.04e-1)" "unprognostic (2.64e-1)" "unprognostic (1.60e-1)" "unprognostic (4.86e-2)" CLPX ENSG00000166855 "Caseinolytic mitochondrial matrix peptidase chaperone subunit X" O76031 15 65148219-65185342 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 218.5;Late spermatids: 423.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 423.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA040262, HPA048199" Approved Supported "Nucleoplasm,Mitochondria,Cytosol,Equatorial segment,Perinuclear theca" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 19 Mitochondria "Nucleoplasm, Cytosol, Equatorial segment, Perinuclear theca" "HPA040262: , HPA048199: " "unprognostic (4.49e-2)" "unprognostic (4.66e-2)" "unprognostic (4.39e-1)" "unprognostic (2.88e-1)" "unprognostic (1.91e-2)" "unprognostic (3.35e-1)" "unprognostic (1.59e-2)" "unprognostic (4.74e-3)" "unprognostic (3.68e-1)" "potential prognostic unfavorable (5.29e-4)" "validated prognostic favorable (1.57e-4)" "validated prognostic favorable (5.57e-5)" "unprognostic (1.46e-3)" "potential prognostic favorable (7.23e-4)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (2.52e-1)" "unprognostic (2.45e-1)" "unprognostic (5.86e-3)" "unprognostic (2.66e-2)" "unprognostic (3.87e-2)" "unprognostic (3.48e-1)" "unprognostic (1.68e-1)" "unprognostic (8.65e-2)" "unprognostic (4.85e-2)" "unprognostic (2.97e-1)" "unprognostic (6.50e-2)" "unprognostic (5.38e-2)" "unprognostic (3.12e-1)" "unprognostic (2.68e-1)" "unprognostic (2.97e-3)" CLRN1 "RP61, USH3, USH3A" ENSG00000163646 "Clarin 1" P58418 3 150926163-150972727 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Sensory transduction, Vision" "Deafness, Disease variant, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 4.7;retina: 11.8" "Cell type enriched" "Detected in some" 8 "Müller glia: 102.1" "Cell type enriched" "Detected in some" 8 "Glial cells: 102.1" "Cell type enhanced" "Detected in some" "lower rhombic lip: 1.4;thalamic excitatory: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA054031 Uncertain "Vesicles,Centrosome,Basal body" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 11: Muller glia cells - Retinal homeostasis" 23 Centrosome "Vesicles, Basal body" "HPA054031: " CLSPN ENSG00000092853 Claspin Q9HAW4 1 35720218-35769978 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.6;lymphoid tissue: 7.3;retina: 6.3;testis: 5.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 176.0;Early primary spermatocytes: 583.4;Erythrocyte progenitors: 151.6;Extravillous trophoblasts: 63.5;Megakaryocyte progenitors: 137.0;Monocyte progenitors: 186.8;Neutrophil progenitors: 62.6;Oocytes: 128.9;Rod photoreceptor cells: 104.2" "Cell type enhanced" "Detected in many" "Erythrocytes: 151.6;Megakaryocytes: 137.0;Mononuclear phagocytes: 186.8;Spermatogenic cell types: 583.4" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Region enriched" "Detected in some" 6 "basal ganglia: 7.8" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1796 "Smooth muscle cells: 179612.1" "Not detected" "Not detected" "HPA026305, HPA026312" Enhanced "Nucleoplasm,Golgi apparatus" Yes Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 3: Early primary spermatocytes - Early meiosis" 39 "Nucleoplasm, Golgi apparatus" "HPA026305: , HPA026312: " "unprognostic (3.00e-1)" "unprognostic (6.55e-2)" "unprognostic (3.97e-2)" "unprognostic (3.95e-1)" "unprognostic (9.73e-2)" "unprognostic (1.00e-2)" "unprognostic (2.53e-1)" "unprognostic (3.82e-2)" "unprognostic (3.02e-2)" "unprognostic (1.88e-2)" "unprognostic (3.23e-2)" "potential prognostic unfavorable (1.89e-7)" "validated prognostic unfavorable (1.44e-5)" "validated prognostic unfavorable (3.13e-5)" "unprognostic (2.38e-1)" "unprognostic (1.54e-2)" "unprognostic (3.68e-2)" "unprognostic (9.77e-2)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (4.42e-3)" "unprognostic (6.86e-2)" "unprognostic (3.08e-2)" "unprognostic (9.71e-3)" "potential prognostic favorable (4.91e-4)" "unprognostic (2.00e-1)" "unprognostic (1.98e-1)" CLSTN2 "CDHR13, CS2, CSTN2, FLJ39113" ENSG00000158258 "Calsyntenin 2" Q9H4D0 3 139935185-140577397 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.7;ovary: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1124.0;Adrenal medulla cells: 457.4;Brain excitatory neurons: 566.4;Early spermatids: 286.7;Fibro-adipogenic progenitors: 206.1;Other brain neurons: 488.1;Ovarian stromal cells: 496.8;Pericytes: 326.4;Proximal tubule cells: 284.9;Retinal ganglion cells: 301.3;Thymic myoid cells: 349.4" "Cell type enhanced" "Detected in many" "Adipocytes: 1124.0;Adrenal endocrine cells: 457.4;Neuronal cells: 566.4;Stromal cells: 496.8" "Cell type enhanced" "Detected in all" "hippocampal CA4: 2121.8;hippocampal dentate gyrus: 2288.4" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 23.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bone cancer: 20.0;testis cancer: 39.3" "Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cell types: 195426.7;Microglia and Neuropil: 335683.7;Neurons: 309767.3" "Tissue enriched" "Detected in some" "ovary: 2433920.9" "HPA031342, HPA061800" Approved Uncertain "Vesicles,Cytokinetic bridge" Yes No 35000 "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "Cytokinetic bridge" "HPA031342: , HPA061800: " "unprognostic (1.00e-2)" "unprognostic (1.79e-1)" "unprognostic (1.06e-1)" "unprognostic (2.67e-2)" "unprognostic (4.82e-3)" "unprognostic (2.34e-3)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (5.69e-2)" "unprognostic (5.44e-2)" "unprognostic (2.19e-1)" "unprognostic (1.09e-1)" "unprognostic (3.42e-1)" "unprognostic (3.08e-2)" "unprognostic (2.30e-1)" CLTC "CLTCL2, Hc" ENSG00000141367 "Clathrin heavy chain" Q00610 17 59619684-59696956 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, Cell cycle, Cell division, Mitosis" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 602.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 1563128243.6" "CAB010389, CAB011571, CAB017155, HPA059143" Approved Enhanced "Endosomes,Lysosomes,Mitotic spindle,Centriolar satellite,Cytosol,Mid piece" Yes No 15000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 129 "Endosomes, Lysosomes" "Mitotic spindle, Centriolar satellite, Cytosol, Mid piece" "CAB010389: , CAB011571: , CAB017155: , HPA059143: " "unprognostic (1.13e-1)" "unprognostic (1.14e-2)" "unprognostic (2.82e-3)" "unprognostic (1.39e-3)" "unprognostic (1.36e-3)" "unprognostic (1.68e-1)" "unprognostic (2.42e-1)" "unprognostic (9.29e-3)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (3.40e-4)" "potential prognostic favorable (5.20e-6)" "unprognostic (6.26e-2)" "unprognostic (9.96e-2)" "potential prognostic unfavorable (6.05e-5)" "unprognostic (1.24e-3)" "unprognostic (5.75e-2)" "unprognostic (1.40e-2)" "unprognostic (1.33e-1)" "unprognostic (2.55e-1)" "unprognostic (2.41e-1)" "unprognostic (3.80e-1)" "unprognostic (2.30e-2)" "unprognostic (2.74e-1)" "unprognostic (2.92e-1)" "unprognostic (2.51e-1)" "unprognostic (3.72e-3)" "unprognostic (7.30e-2)" "unprognostic (3.26e-1)" "unprognostic (3.41e-1)" "unprognostic (1.02e-1)" "unprognostic (2.38e-1)" CLUAP1 "CFAP22, FAP22, FLJ13297, IFT38, KIAA0643" ENSG00000103351 "Clusterin associated protein 1" Q96AJ1 16 3500976-3539048 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 163.4;Fallopian tube ciliated cells: 137.2;Late primary spermatocytes: 222.2;Respiratory ciliated cells: 218.0" "Cell type enhanced" "Detected in all" "Ciliated cells: 218.0;Spermatogenic cell types: 222.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 1254104.4;Fallopian tube cells: 3351883.9" "Tissue enriched" "Detected in single" 43091 "fallopian tube: 4309141.4" "HPA036976, HPA044191" Uncertain Supported "Nucleoplasm,Vesicles,Actin filaments,Primary cilium" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 46 "Nucleoplasm, Primary cilium" "Vesicles, Actin filaments" "HPA036976: , HPA044191: " "unprognostic (4.81e-1)" "unprognostic (3.45e-2)" "unprognostic (2.17e-1)" "unprognostic (2.53e-2)" "unprognostic (1.63e-1)" "unprognostic (8.75e-3)" "unprognostic (2.32e-1)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (3.72e-2)" "potential prognostic favorable (4.33e-7)" "unprognostic (1.30e-2)" "unprognostic (1.77e-1)" "unprognostic (9.24e-2)" "unprognostic (8.63e-2)" "unprognostic (3.84e-2)" "unprognostic (2.09e-1)" "unprognostic (6.62e-2)" "unprognostic (5.19e-2)" "unprognostic (1.18e-1)" "unprognostic (6.66e-2)" "unprognostic (2.49e-2)" "unprognostic (8.99e-2)" "unprognostic (8.31e-2)" "unprognostic (7.83e-3)" "unprognostic (1.32e-2)" "unprognostic (2.41e-1)" "unprognostic (2.39e-2)" "unprognostic (2.95e-1)" "unprognostic (2.51e-1)" "unprognostic (7.64e-3)" CMTM5 "CKLFSF5, FLJ37521" ENSG00000166091 "CKLF like MARVEL transmembrane domain containing 5" Q96DZ9 14 23376773-23379772 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "brain: 330.7" "Group enriched" "Detected in some" 14 "Megakaryocytes: 1570.1;Platelets: 2685.0" "Group enriched" "Detected in some" 14 "Megakaryocytes: 1570.1;Platelets: 2685.0" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 63.2;oligodendrocyte: 204.9" "Group enriched" "Detected in some" 41 "Glioblastoma Multiforme (TCGA): 47.6;Skin Cutaneous Melanoma (TCGA): 21.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 20.8" "Lineage enriched" "Detected in many" 19 "granulocytes: 20.8" "Cancer enhanced" "Detected in some" "Leukemia: 7.4;skin cancer: 3.5" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skin - Smooth muscle cells, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Astrocytes and Neuropil: 2824504.7" "Group enriched" "Detected in some" "bone marrow: 805554.7;cerebral cortex: 1037592.2;fallopian tube: 949203.0;lymphoid tissue: 485129.1" HPA052338 Enhanced Approved "Golgi apparatus,Vesicles" NA NA 470000 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 40 "Golgi apparatus, Vesicles" "HPA052338: " "unprognostic (1.98e-2)" "unprognostic (2.71e-1)" "unprognostic (3.63e-3)" "unprognostic (2.80e-1)" CMTM7 "CKLFSF7, FLJ30992" ENSG00000153551 "CKLF like MARVEL transmembrane domain containing 7" Q96FZ5 3 32391698-32483067 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast secretory cells: 202.5;cDC: 220.3;Hofbauer cells: 224.6;Kupffer cells: 247.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 232.6;leukocyte: 122.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA077409 Approved "Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 39 "Plasma membrane" "HPA077409: " "unprognostic (4.52e-1)" "unprognostic (1.35e-2)" "unprognostic (1.77e-3)" "unprognostic (2.33e-3)" "unprognostic (9.16e-2)" "unprognostic (5.26e-3)" "unprognostic (2.91e-2)" "unprognostic (2.83e-1)" "unprognostic (1.33e-1)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (4.72e-5)" "unprognostic (4.22e-2)" "unprognostic (1.16e-1)" "validated prognostic unfavorable (1.51e-4)" "validated prognostic unfavorable (2.90e-4)" "unprognostic (1.08e-2)" "unprognostic (1.72e-2)" "unprognostic (8.56e-2)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (8.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.74e-3)" "unprognostic (9.92e-3)" "unprognostic (2.90e-2)" "unprognostic (1.84e-2)" "unprognostic (3.50e-1)" "unprognostic (2.71e-2)" "unprognostic (3.34e-1)" CMTR1 "FTSJD2, ISG95, KIAA0082, MTr1" ENSG00000137200 "Cap methyltransferase 1" Q8N1G2 6 37433219-37482827 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 130.7" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 130.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 20802795.4" "Tissue enhanced" "Detected in many" "heart muscle: 16616734.6" "HPA029954, HPA029979, HPA029980" Enhanced Enhanced Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 28: Non-specific - Nuclear processes" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 21 Nucleoplasm Vesicles "HPA029954: , HPA029979: , HPA029980: " "unprognostic (2.83e-2)" "unprognostic (1.38e-1)" "unprognostic (2.91e-1)" "unprognostic (5.64e-2)" "unprognostic (2.90e-1)" "unprognostic (1.66e-1)" "unprognostic (2.52e-3)" "unprognostic (1.83e-1)" "unprognostic (4.43e-3)" "potential prognostic favorable (1.49e-4)" "unprognostic (7.92e-3)" "unprognostic (5.66e-2)" "unprognostic (7.91e-3)" "unprognostic (3.30e-2)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (2.66e-1)" "unprognostic (8.45e-3)" "unprognostic (4.58e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (4.08e-4)" "unprognostic (6.79e-2)" "unprognostic (7.36e-2)" "unprognostic (8.45e-2)" "unprognostic (3.88e-1)" "unprognostic (1.90e-1)" "unprognostic (1.31e-2)" CNBD2 "C20orf152, CNMPD1, dJ954P9.1" ENSG00000149646 "Cyclic nucleotide binding domain containing 2" Q96M20 20 35954564-36030700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 24.1" "Cell type enhanced" "Detected in many" "Early spermatids: 353.2;Epididymal principal cells: 65.4;Late primary spermatocytes: 153.4;Late spermatids: 146.8" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 353.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043182 Uncertain Approved "Nucleoli,Actin filaments,Cytosol,Mid piece" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nucleoli, Mid piece" "Actin filaments, Cytosol" "HPA043182: " "unprognostic (1.24e-1)" "unprognostic (1.17e-1)" "unprognostic (1.62e-3)" "unprognostic (5.99e-2)" "unprognostic (1.37e-1)" "unprognostic (2.79e-2)" "unprognostic (3.78e-2)" "unprognostic (2.47e-1)" "unprognostic (1.55e-2)" "unprognostic (6.43e-2)" "unprognostic (4.64e-3)" "unprognostic (7.11e-3)" "unprognostic (5.45e-3)" "unprognostic (4.01e-2)" "unprognostic (4.57e-2)" "unprognostic (2.10e-1)" "unprognostic (4.19e-2)" "potential prognostic favorable (7.53e-4)" "unprognostic (2.44e-2)" "unprognostic (2.63e-1)" "unprognostic (8.48e-3)" "unprognostic (2.08e-1)" "unprognostic (9.36e-2)" "unprognostic (4.13e-2)" "unprognostic (4.97e-2)" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" CNBP "CNBP1, DM2, RNF163, ZCCHC22, ZNF9" ENSG00000169714 "CCHC-type zinc finger nucleic acid binding protein" P62633 3 129167827-129183922 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA063097 Approved Nucleoplasm,Cytosol NA NA 100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 15: Non-specific - Protein processing" 32 Nucleoplasm Cytosol "HPA063097: " "unprognostic (2.17e-2)" "unprognostic (1.66e-1)" "unprognostic (5.21e-2)" "unprognostic (6.92e-2)" "unprognostic (6.82e-2)" "unprognostic (3.26e-2)" "unprognostic (1.65e-2)" "unprognostic (5.81e-2)" "unprognostic (2.75e-1)" "unprognostic (5.80e-3)" "validated prognostic favorable (6.48e-5)" "validated prognostic favorable (4.94e-4)" "unprognostic (4.04e-2)" "unprognostic (1.10e-3)" "unprognostic (4.65e-3)" "unprognostic (3.12e-2)" "unprognostic (1.45e-2)" "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.24e-1)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (3.65e-2)" "unprognostic (1.61e-1)" "unprognostic (3.29e-2)" "unprognostic (4.77e-2)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "unprognostic (1.81e-2)" CNFN PLAC8L2 ENSG00000105427 Cornifelin Q9BYD5 19 42387019-42390297 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1123.8;esophagus: 2986.1;vagina: 1350.2" "Cell type enriched" "Detected in many" 80 "Esophageal apical cells: 99030.0" "Cell type enriched" "Detected in many" 80 "Apical squamous epithelial cells: 99030.0" "Cell type enhanced" "Detected in many" "endothelial cell: 4.5;hippocampal CA4: 4.7" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 787.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 11 "memory B-cell: 61.4;naive B-cell: 70.6" "Lineage enriched" "Detected in many" 12 "B-cells: 70.6" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049073, HPA053997" Enhanced Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 18: Non-specific - Translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 10 Microtubules "Cytokinetic bridge" "HPA049073: , HPA053997: " "unprognostic (1.05e-1)" "unprognostic (5.30e-2)" "unprognostic (1.90e-1)" "unprognostic (4.48e-3)" "unprognostic (1.13e-1)" "unprognostic (8.30e-2)" "unprognostic (3.38e-2)" "unprognostic (1.32e-2)" "unprognostic (8.57e-2)" "unprognostic (1.59e-3)" "unprognostic (3.72e-3)" "unprognostic (5.29e-2)" "unprognostic (2.43e-2)" "unprognostic (1.26e-3)" "unprognostic (2.34e-2)" "unprognostic (2.02e-2)" "unprognostic (1.01e-2)" "unprognostic (1.22e-1)" "unprognostic (8.26e-2)" "unprognostic (7.10e-2)" "unprognostic (1.00e-1)" "unprognostic (1.07e-1)" "unprognostic (1.68e-1)" "unprognostic (2.48e-1)" "unprognostic (3.77e-2)" "unprognostic (2.68e-1)" "unprognostic (3.36e-2)" "unprognostic (5.07e-2)" "potential prognostic favorable (3.22e-5)" "unprognostic (4.12e-1)" CNGA1 "CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49" ENSG00000198515 "Cyclic nucleotide gated channel subunit alpha 1" P29973 4 47935977-48016681 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport, Vision" "Calcium channel, Ion channel, Ligand-gated ion channel, Sodium channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 244.8" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 336.9;Rod photoreceptor cells: 1024.5" "Group enriched" "Detected in many" 4 "Apical squamous epithelial cells: 336.9;Neuronal cells: 1024.5" "Cell type enhanced" "Detected in many" "pericyte: 67.8;vascular associated smooth muscle cell: 38.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076168 Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Mitotic spindle,Primary cilium,Primary cilium tip,Mid piece,Principal piece" Yes NA "Cluster 42: Retina - Visual perception" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 79: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Mid piece, Principal piece" "Plasma membrane, Mitotic spindle, Primary cilium, Primary cilium tip" "HPA076168: " "unprognostic (1.03e-1)" "unprognostic (7.73e-2)" "unprognostic (1.14e-1)" "unprognostic (6.01e-3)" "unprognostic (4.58e-2)" "unprognostic (1.79e-1)" "unprognostic (1.59e-2)" "unprognostic (4.25e-2)" "potential prognostic favorable (5.64e-5)" "unprognostic (6.55e-2)" "unprognostic (5.75e-3)" "unprognostic (9.08e-3)" "unprognostic (6.53e-2)" "unprognostic (3.24e-2)" "unprognostic (2.85e-1)" "unprognostic (1.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.51e-1)" "unprognostic (1.58e-1)" "unprognostic (1.26e-2)" "unprognostic (6.36e-2)" "unprognostic (2.19e-1)" "unprognostic (1.78e-1)" "unprognostic (1.87e-2)" "unprognostic (9.43e-2)" CNGA3 "ACHM2, CCNC1, CCNCa, CNCG3, CNG3" ENSG00000144191 "Cyclic nucleotide gated channel subunit alpha 3" Q16281 2 98346188-98398601 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Sensory transduction, Sodium transport, Transport, Vision" "Calcium channel, Ion channel, Ligand-gated ion channel, Sodium channel" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.7;intestine: 5.1;pituitary gland: 10.0;retina: 5.4" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 16.2;Cone photoreceptor cells: 43.5;Early spermatids: 12.1;Lactotrophs: 57.5;Late primary spermatocytes: 14.2;Late spermatids: 11.5;Other brain neurons: 11.5;Somatotrophs: 40.3;Thyrotrophs: 43.1" "Cell type enhanced" "Detected in some" "Ciliated cells: 16.2;Neuronal cells: 43.5;Pituitary endocrine cells: 57.5;Spermatogenic cell types: 14.2" "Cell type enhanced" "Detected in some" "astrocyte: 11.5;choroid plexus epithelial cell: 10.8;ependymal cell: 10.5" "Cancer enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 15.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Neuroblastoma: 1.5" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Group enriched" "Detected in some" 6 "basal ganglia: 1.8;hypothalamus: 1.9" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 402 "Smooth muscle cells: 40156.8" "Not detected" "Not detected" "HPA049378, CAB079025" Approved Approved Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 22: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Mid piece, Principal piece, End piece" "CAB079025: , HPA049378: " "unprognostic (2.37e-1)" "unprognostic (9.01e-2)" "potential prognostic unfavorable (3.80e-4)" "potential prognostic favorable (4.79e-4)" "unprognostic (1.34e-1)" CNGB1 "CNCG2, CNCG3L, CNGB1B, GAR1, GARP, RCNC2, RCNCb, RP45" ENSG00000070729 "Cyclic nucleotide gated channel subunit beta 1" Q14028 16 57882340-57971128 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Olfaction, Sensory transduction, Sodium transport, Transport, Vision" "Calcium channel, Ion channel, Ligand-gated ion channel, Sodium channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 59 "retina: 557.0" "Group enriched" "Detected in many" 12 "Cone photoreceptor cells: 395.4;Rod photoreceptor cells: 1524.0" "Cell type enriched" "Detected in many" 20 "Neuronal cells: 1524.0" "Cell type enhanced" "Detected in many" "amygdala excitatory: 115.6;hippocampal dentate gyrus: 228.9;upper-layer intratelencephalic: 129.5" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 5.2;Kidney Chromophobe (TCGA): 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 11.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Testis - Late spermatids" "Region enhanced" "Detected in some" "hypothalamus: 4.5" "Cell type enriched" "Detected in single" 740 "Large ducts: 74019.6" "Tissue enriched" "Detected in single" 1793 "intestine: 179335.6" HPA060355 Approved "Plasma membrane,Cytosol" No NA "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA060355: " "unprognostic (1.32e-2)" "unprognostic (3.14e-2)" "unprognostic (2.66e-1)" "unprognostic (2.15e-1)" "unprognostic (1.36e-3)" "unprognostic (1.55e-1)" "unprognostic (3.41e-2)" "unprognostic (3.82e-1)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (8.66e-4)" CNN1 "Sm-Calp, SMCC" ENSG00000130176 "Calponin 1" P51911 19 11538767-11550323 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 2087.4;intestine: 2743.0;smooth muscle: 2059.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 837.0;Decidual stromal cells: 451.4;Early spermatids: 449.9;Late spermatids: 741.2;Peritubular myoid cells: 185.1;Salivary myoepithelial cells: 277.5;Smooth muscle cells: 2790.8;Vascular smooth muscle cells: 526.4" "Cell type enhanced" "Detected in many" "Mural cells: 526.4;Secretory gland support: 837.0;Smooth muscle cells: 2790.8;Spermatogenic cell types: 741.2;Stromal cells: 451.4" "Cell type enriched" "Detected in some" 104 "vascular associated smooth muscle cell: 146.9" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 406.5;Stomach Adenocarcinoma (TCGA): 341.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 58.4;testis cancer: 66.8" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells, Testis - Late spermatids, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 3893968352.4" "Tissue enhanced" "Detected in many" "blood vessel: 1438769483.2;Stomach: 1439317514.1" "CAB000007, HPA014263" Enhanced Approved "Actin filaments" No No 51000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Actin filaments" "CAB000007: , HPA014263: " "potential prognostic favorable (9.62e-4)" "unprognostic (2.22e-3)" "unprognostic (1.47e-1)" "unprognostic (2.23e-1)" "unprognostic (2.47e-2)" "unprognostic (5.54e-2)" "unprognostic (2.28e-1)" "unprognostic (3.51e-3)" "unprognostic (1.91e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (3.07e-2)" "potential prognostic unfavorable (5.88e-7)" "unprognostic (7.70e-3)" "unprognostic (3.47e-1)" "unprognostic (8.94e-2)" "unprognostic (1.01e-1)" "unprognostic (6.66e-3)" "unprognostic (4.27e-2)" "unprognostic (1.23e-2)" "unprognostic (1.86e-2)" "unprognostic (2.35e-1)" "unprognostic (7.64e-2)" "unprognostic (1.49e-1)" "unprognostic (9.99e-3)" "unprognostic (2.67e-2)" "unprognostic (4.94e-3)" "unprognostic (8.96e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-3)" "unprognostic (6.31e-2)" CNTD1 "CNTD, FLJ40137" ENSG00000176563 "Cyclin N-terminal domain containing 1" Q8N815 17 42798800-42811587 "Predicted intracellular proteins, Predicted membrane proteins" Meiosis "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "testis: 39.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 159.6;Early spermatids: 61.3;Gastric chief cells: 55.7;Late primary spermatocytes: 181.0;Late spermatids: 174.3;Mucous neck cells: 54.7;Parietal cells: 111.4;Respiratory ciliated cells: 50.6" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 111.4;Spermatogenic cell types: 181.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA072363 Approved Nucleoplasm,Vesicles NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 70: DU4475 - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" Nucleoplasm Vesicles "HPA072363: " "unprognostic (9.90e-2)" "unprognostic (6.62e-3)" "unprognostic (7.32e-3)" "unprognostic (1.52e-1)" "unprognostic (1.38e-2)" "unprognostic (2.19e-2)" "unprognostic (1.89e-3)" "unprognostic (2.41e-1)" "unprognostic (2.12e-1)" "unprognostic (4.22e-3)" CNTRL "CEP1, CEP110" ENSG00000119397 Centriolin Q7Z7A1 9 121074660-121177729 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20.3;testis: 28.4" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 406.1;Ependymal cells: 253.1;Fallopian tube ciliated cells: 257.8;Late primary spermatocytes: 401.9;Monocyte progenitors: 413.7;Neutrophil progenitors: 332.1;Respiratory ciliated cells: 315.6" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 413.7;Spermatogenic cell types: 406.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 4599341.3;Fallopian tube cells: 10543262.3;Neutrophils: 4430712.6;T-cells: 4948647.2" "Tissue enhanced" "Detected in some" "bone marrow: 6317308.7" "HPA020468, HPA020480, HPA051583" Approved Supported "Golgi apparatus,Plasma membrane,Centriolar satellite,Centrosome,Basal body,Cytosol,Flagellar centriole" NA Yes "Cluster 22: Eosinophils - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 5 "Centrosome, Basal body, Flagellar centriole" "Golgi apparatus, Plasma membrane, Centriolar satellite, Cytosol" "HPA020468: , HPA020480: , HPA051583: " "unprognostic (1.81e-3)" "unprognostic (7.84e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (6.66e-3)" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "potential prognostic favorable (3.61e-4)" "unprognostic (2.19e-1)" "unprognostic (2.43e-3)" "unprognostic (1.32e-1)" "unprognostic (8.29e-2)" "unprognostic (6.07e-2)" "unprognostic (3.06e-1)" "unprognostic (1.94e-1)" "unprognostic (5.76e-3)" "unprognostic (2.03e-1)" "unprognostic (7.06e-3)" "unprognostic (7.73e-2)" "unprognostic (7.42e-2)" "unprognostic (1.75e-1)" "unprognostic (1.50e-1)" "unprognostic (5.04e-2)" "unprognostic (5.98e-3)" "potential prognostic favorable (8.97e-6)" "unprognostic (3.85e-2)" "unprognostic (4.80e-2)" "unprognostic (3.55e-1)" "unprognostic (1.31e-1)" "unprognostic (1.68e-1)" COA5 "C2orf64, FLJ27524, MGC52110, Pet191" ENSG00000183513 "Cytochrome c oxidase assembly factor 5" Q86WW8 2 98599314-98608515 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 147.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA057768 Uncertain Supported Mitochondria No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "HPA057768: " "unprognostic (1.86e-3)" "unprognostic (2.46e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (3.32e-2)" "unprognostic (2.25e-2)" "unprognostic (1.68e-2)" "unprognostic (1.10e-1)" "unprognostic (7.28e-2)" "unprognostic (1.20e-2)" "unprognostic (2.69e-3)" "unprognostic (5.15e-2)" "unprognostic (1.20e-2)" "unprognostic (1.66e-1)" "unprognostic (6.02e-2)" "unprognostic (1.06e-3)" "unprognostic (2.48e-3)" "unprognostic (1.68e-2)" "unprognostic (1.65e-2)" "unprognostic (6.43e-2)" "unprognostic (1.97e-2)" "unprognostic (4.73e-2)" "unprognostic (3.24e-2)" "unprognostic (3.07e-3)" "unprognostic (1.52e-1)" "unprognostic (1.66e-2)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (1.53e-1)" COG8 "DOR1, FLJ22315" ENSG00000213380 "Component of oligomeric golgi complex 8" Q96MW5 16 69320140-69339583 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.4;Epicardial cells: 52.3" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 52.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4645470.0" "HPA041406, HPA049429" Approved Supported "Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 22 "Golgi apparatus" "HPA041406: , HPA049429: " "unprognostic (9.26e-2)" "unprognostic (1.98e-2)" "unprognostic (3.76e-1)" "unprognostic (6.89e-3)" "unprognostic (1.69e-1)" "unprognostic (2.96e-1)" "unprognostic (2.51e-1)" "potential prognostic favorable (3.51e-5)" "unprognostic (2.21e-1)" "unprognostic (9.37e-2)" "potential prognostic favorable (2.26e-5)" "unprognostic (1.29e-2)" "potential prognostic favorable (4.15e-4)" "unprognostic (3.27e-2)" "unprognostic (1.11e-1)" "unprognostic (5.46e-2)" "unprognostic (5.39e-3)" "unprognostic (2.09e-2)" "unprognostic (1.84e-2)" "unprognostic (5.03e-1)" "unprognostic (5.30e-2)" "potential prognostic favorable (8.52e-4)" "unprognostic (1.13e-1)" "unprognostic (4.30e-1)" "unprognostic (1.85e-2)" "unprognostic (3.24e-1)" "unprognostic (1.35e-1)" "unprognostic (2.10e-1)" "unprognostic (4.47e-1)" "unprognostic (1.95e-2)" "unprognostic (8.76e-2)" COL10A1 ENSG00000123500 "Collagen type X alpha 1 chain" Q03692 6 116118909-116158747 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 8.3;ovary: 5.5" "Cell type enhanced" "Detected in many" "Adipocytes: 111.4;Cardiomyocytes: 587.1;Epicardial cells: 152.4;Myonuclei: 100.4" "Cell type enhanced" "Detected in many" "Adipocytes: 111.4;Barrier epithelial cells: 152.4;Myocytes: 587.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 100.5;oligodendrocyte: 59.2" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 173.5;Pancreatic Adenocarcinoma (TCGA): 175.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 2.9;thyroid cancer: 3.3" "Skin - Outer root sheath cells" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Smooth muscle cells: 6496692.0" "Tissue enriched" "Detected in some" "blood vessel: 741870.6" HPA053268 Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" NA NA 62000 "Cluster 55: Breast - Lactation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 17 "Endoplasmic reticulum" "HPA053268: " "unprognostic (8.27e-3)" "unprognostic (7.59e-2)" "unprognostic (5.75e-2)" "unprognostic (4.53e-2)" "unprognostic (1.43e-2)" "unprognostic (2.79e-3)" "unprognostic (4.26e-3)" "unprognostic (2.73e-2)" "unprognostic (4.06e-2)" "unprognostic (1.04e-3)" "unprognostic (1.14e-1)" "unprognostic (1.06e-1)" "unprognostic (3.44e-1)" "unprognostic (2.42e-1)" "unprognostic (3.79e-2)" "unprognostic (8.13e-2)" "unprognostic (1.46e-1)" "unprognostic (9.58e-3)" "potential prognostic unfavorable (4.34e-6)" "unprognostic (4.50e-2)" "unprognostic (4.15e-2)" "unprognostic (1.52e-1)" "unprognostic (6.45e-2)" "unprognostic (2.62e-2)" "unprognostic (3.31e-1)" "unprognostic (4.53e-3)" "unprognostic (1.04e-1)" "unprognostic (3.43e-1)" "unprognostic (1.51e-2)" COL11A1 "CO11A1, COLL6, DFNA37, STL2" ENSG00000060718 "Collagen type XI alpha 1 chain" P12107 1 102876467-103108872 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, Ectodermal dysplasia, Non-syndromic deafness, Stickler syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "placenta: 18.9;retina: 8.9" "Cell type enhanced" "Detected in many" "Astrocytes: 91.8;Brain inhibitory neurons: 90.1;Müller glia: 99.1;Oligodendrocyte progenitor cells: 684.0;Oligodendrocytes: 161.0;Pituicytes/FSCs: 432.5;Pituitary stem cells: 202.4;Retinal amacrine cells: 159.6" "Cell type enhanced" "Detected in many" "Glial cells: 684.0;Neuronal cells: 159.6;Stem cells: 202.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 855.2;oligodendrocyte precursor cell: 815.0" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 32.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 252.9" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Smooth muscle cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 326400.3;Large ducts: 245201.7;Smooth muscle cells: 231458.6" "Tissue enriched" "Detected in some" "skeletal muscle: 11895275.6" HPA058335 Supported "Endoplasmic reticulum" "Secreted to extracellular matrix" "No annotated function" No No 540000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Endoplasmic reticulum" "HPA058335: " "unprognostic (1.45e-1)" "unprognostic (3.12e-2)" "unprognostic (2.63e-2)" "unprognostic (2.43e-2)" "unprognostic (5.19e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.41e-2)" "unprognostic (3.03e-2)" "potential prognostic unfavorable (3.28e-5)" "unprognostic (2.77e-2)" "unprognostic (3.20e-1)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.31e-3)" "unprognostic (2.51e-1)" "unprognostic (5.67e-2)" "unprognostic (5.11e-2)" "potential prognostic unfavorable (7.66e-8)" "unprognostic (5.75e-3)" "unprognostic (4.28e-1)" "unprognostic (3.56e-1)" "unprognostic (1.62e-2)" "unprognostic (7.39e-2)" "unprognostic (1.14e-2)" "unprognostic (6.45e-2)" "unprognostic (1.57e-2)" COL15A1 ENSG00000204291 "Collagen type XV alpha 1 chain" P39059 9 98943179-99070792 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 215.4" "Cell type enhanced" "Detected in many" "Adipocytes: 184.0;Adrenal cortex cells: 335.6;Decidual stromal cells: 309.6;Endometrial stromal cells: 146.7;Fibro-adipogenic progenitors: 927.3;Fibroblasts: 244.0;Leydig cells: 712.1;Peritubular myoid cells: 730.8;Vascular endothelial cells: 286.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 335.6;Fibro-adipogenic progenitors: 927.3;Leydig cells: 712.1;Stromal cells: 730.8" "Cell type enriched" "Detected in many" 17 "fibroblast: 502.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 13.8;skin cancer: 14.8" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 7 "spinal cord: 56.0" "Group enriched" "Detected in many" "Capillaries: 106746557.4;Cardiomyocytes: 45427025.5;Pancreatic islets: 30724843.4;Skeletal myofibers: 29685518.5;Smooth muscle cells: 83502460.0" "Tissue enhanced" "Detected in many" "blood vessel: 350299536.5" "HPA017913, HPA017915" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to extracellular matrix" "Developmental protein" NA NA 6700000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Endoplasmic reticulum" "HPA017913: , HPA017915: " "unprognostic (1.25e-2)" "unprognostic (3.51e-1)" "unprognostic (6.09e-2)" "unprognostic (1.41e-2)" "unprognostic (1.80e-1)" "unprognostic (2.91e-1)" "unprognostic (1.28e-1)" "unprognostic (2.96e-2)" "unprognostic (2.37e-2)" "unprognostic (3.34e-1)" "potential prognostic favorable (7.29e-4)" "unprognostic (1.16e-3)" "potential prognostic unfavorable (1.91e-4)" "potential prognostic favorable (9.95e-4)" "unprognostic (4.75e-3)" "unprognostic (6.05e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (5.40e-2)" "unprognostic (1.87e-2)" "unprognostic (1.75e-1)" "unprognostic (7.37e-2)" "unprognostic (2.06e-1)" "unprognostic (8.02e-2)" "unprognostic (1.22e-1)" "unprognostic (4.91e-2)" "unprognostic (6.42e-2)" "unprognostic (1.49e-2)" "unprognostic (5.31e-3)" "unprognostic (1.01e-1)" "unprognostic (2.46e-2)" "unprognostic (3.87e-1)" COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skin 1: 548.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1195.6;Breast myoepithelial cells: 265.2;Colonocytes: 148.3;Enterocytes: 121.0;Epididymal basal cells: 122.2;Esophageal basal cells: 151.4;Medullary thymic epithelial cells: 199.2;Ocular epithelial cells: 738.2;Salivary basal cells: 163.2;Salivary myoepithelial cells: 144.1;Suprabasal keratinocytes: 154.2" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 738.2;Basal cells: 1195.6;Secretory gland support: 265.2" "Cell type enhanced" "Detected in some" "ependymal cell: 1.7;medium spiny neuron: 1.6;midbrain-derived inhibitory: 1.4" "Cancer enriched" "Detected in many" 4 "Head and Neck Squamous Cell Carcinoma (TCGA): 509.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 200.6;head and neck cancer: 440.5" "Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Spleen - Neutrophils_1, Stomach - Gastric mucous cells" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Keratinocytes: 45969283.9" "Tissue enriched" "Detected in some" "skin: 4059407.5" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" "No annotated function" NA NA 24000 "Cluster 37: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 14 "Plasma membrane" "Golgi apparatus" "HPA043673: , HPA052963: " "unprognostic (1.00e-1)" "potential prognostic favorable (1.86e-5)" "unprognostic (3.71e-1)" "unprognostic (7.85e-2)" "unprognostic (1.75e-1)" "unprognostic (2.60e-1)" "unprognostic (2.52e-1)" "unprognostic (3.46e-1)" "unprognostic (2.25e-1)" "unprognostic (5.44e-2)" "unprognostic (8.05e-2)" "unprognostic (5.98e-2)" "unprognostic (2.48e-3)" "potential prognostic unfavorable (3.96e-7)" "unprognostic (5.57e-3)" "unprognostic (6.09e-2)" "unprognostic (1.51e-1)" "unprognostic (2.41e-2)" "unprognostic (8.04e-2)" "unprognostic (1.13e-1)" "unprognostic (1.47e-1)" "unprognostic (3.41e-2)" "unprognostic (2.28e-1)" COL1A1 OI4 ENSG00000108821 "Collagen type I alpha 1 chain" P02452 17 50184101-50201632 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Dwarfism, Ehlers-Danlos syndrome, FDA approved drug targets, Osteogenesis imperfecta, Osteoporosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1248.6;gallbladder: 1134.3;ovary: 1143.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 637.4;Endometrial stromal cells: 1897.4;Fibroblasts: 1258.4;Hepatic stellate cells: 6616.2;Leydig cells: 590.8;Ovarian stromal cells: 434.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 1258.4;Stellate cells: 6616.2;Stromal cells: 1897.4" "Group enriched" "Detected in some" 6 "fibroblast: 118.6;vascular associated smooth muscle cell: 32.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Brain cancer: 1387.0" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Pituitary gland - Corticotropes, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 170.5" "Cell type enhanced" "Detected in all" "Keratinocytes: 4068264254.3;Smooth muscle cells: 5765977380.2" "Group enriched" "Detected in all" "blood vessel: 14843316702.7;skin: 58314872273.5" "HPA011795, HPA012111" Approved Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 150000000 "Cluster 75: Ovary - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 44 "Endoplasmic reticulum" Vesicles "HPA011795: , HPA012111: " "unprognostic (1.71e-2)" "unprognostic (3.02e-1)" "unprognostic (9.50e-2)" "unprognostic (5.85e-3)" "unprognostic (2.11e-2)" "unprognostic (2.74e-1)" "unprognostic (6.08e-2)" "unprognostic (9.19e-3)" "unprognostic (1.40e-1)" "unprognostic (1.38e-2)" "unprognostic (1.98e-3)" "unprognostic (1.00e-1)" "potential prognostic unfavorable (8.35e-7)" "unprognostic (4.68e-2)" "unprognostic (1.75e-1)" "potential prognostic unfavorable (9.95e-4)" "unprognostic (3.45e-2)" "unprognostic (6.12e-2)" "unprognostic (3.04e-1)" "unprognostic (4.06e-3)" "unprognostic (3.29e-2)" "unprognostic (4.66e-2)" "unprognostic (9.19e-2)" "unprognostic (9.67e-2)" "unprognostic (4.08e-2)" "unprognostic (7.63e-3)" "unprognostic (3.39e-2)" "unprognostic (9.07e-3)" "unprognostic (6.56e-2)" "unprognostic (5.02e-2)" "unprognostic (2.00e-1)" COL28A1 ENSG00000215018 "Collagen type XXVIII alpha 1 chain" Q2UY09 7 7356203-7535873 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 378.5;Endometrial ciliated cells: 139.1;Ependymal cells: 247.1;Lacrimal acinar cells: 231.9;Respiratory ciliated cells: 208.2;Salivary acinar cells: 132.9;Schwann cells: 444.0;Thymic myoid cells: 284.2" "Cell type enhanced" "Detected in many" "Acinar cells: 231.9;Ciliated cells: 247.1;Glial cells: 444.0;Pituitary endocrine cells: 378.5;Stromal cells: 284.2" "Cell type enhanced" "Detected in all" "ependymal cell: 241.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 10.2" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Pituitary gland - Corticotropes, Thyroid gland - Fibroblasts" "Region enriched" "Detected in single" 8 "olfactory bulb: 3.6" "Region enriched" "Detected in some" 31 "spinal cord: 44.1" "Group enriched" "Detected in some" "Capillaries: 18327920.0;Cardiomyocytes: 14940844.5" "Tissue enhanced" "Detected in many" "heart muscle: 18479627.0" "HPA043844, HPA060468" Uncertain Approved Nucleoplasm,Cytosol "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 61: Schwann cells & Melanocytes - Mixed function" Cytosol Nucleoplasm "HPA043844: , HPA060468: " "unprognostic (1.09e-1)" "unprognostic (5.83e-2)" "unprognostic (2.23e-2)" "unprognostic (1.19e-2)" "unprognostic (4.32e-2)" "unprognostic (4.43e-2)" "unprognostic (5.85e-2)" "unprognostic (8.39e-2)" "unprognostic (3.48e-2)" "unprognostic (1.27e-3)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (6.61e-2)" "unprognostic (2.14e-1)" "unprognostic (8.58e-3)" "unprognostic (7.06e-3)" "unprognostic (7.57e-2)" "unprognostic (1.34e-1)" "unprognostic (9.43e-3)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (6.01e-3)" "unprognostic (1.61e-2)" "unprognostic (3.05e-2)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (2.85e-2)" "unprognostic (6.16e-2)" "unprognostic (3.99e-1)" COL2A1 "AOM, SEDC, STL1" ENSG00000139219 "Collagen type II alpha 1 chain" P02458 12 47972967-48004554 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted secreted proteins" "Cancer-related genes, Cataract, Deafness, Disease variant, Dwarfism, FDA approved drug targets, Stickler syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "epididymis: 18.0;pituitary gland: 8.8;retina: 5.2;stomach 1: 11.6" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Epididymal principal cells: 58.3;Gonadotrophs: 41.0;Granulosa cells: 19.5;Müller glia: 26.2;Neuroendocrine cells: 42.7;Parietal cells: 127.3;Pituitary stem cells: 18.6;Retinal amacrine cells: 41.6;Tuft cells: 34.6" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 42.7;Gastric glandular cells: 127.3;Neuronal cells: 41.6;Pituitary endocrine cells: 41.0;Reproductive supporting cells: 58.3;Secretory gland support: 34.6" "Cell type enhanced" "Detected in some" "fibroblast: 2.8;hippocampal dentate gyrus: 5.7" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 22.3;Prostate Adenocarcinoma (TCGA): 19.7;Skin Cutaneous Melanoma (TCGA): 14.8;Testicular Germ Cell Tumor (TCGA): 22.7;Uterine Corpus Endometrial Carcinoma (TCGA): 8.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "liver cancer: 78.5" "Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Oocytes: 1678676.9" "Tissue enriched" "Detected in many" "skin: 22822072.9" "CAB002214, HPA055753" Approved Approved Nucleoplasm "Secreted to extracellular matrix" "No annotated function" No NA 13000000 "Cluster 22: Epididymis - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 3 Nucleoplasm "CAB002214: , HPA055753: " "unprognostic (6.77e-3)" "unprognostic (2.16e-1)" "unprognostic (5.49e-2)" "unprognostic (7.27e-2)" "unprognostic (2.63e-2)" "unprognostic (1.11e-1)" "unprognostic (5.52e-2)" "unprognostic (7.13e-2)" "unprognostic (1.04e-1)" "unprognostic (6.95e-2)" "unprognostic (7.34e-2)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (1.93e-1)" "unprognostic (2.54e-2)" "unprognostic (1.91e-1)" "unprognostic (5.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.31e-1)" COL5A1 ENSG00000130635 "Collagen type V alpha 1 chain" P20908 9 134641803-134844843 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Heparin-binding "Cancer-related genes, Disease variant, Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 144.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 175.9;Endometrial stromal cells: 229.0;Ependymal cells: 89.4;Epididymal efferent duct ciliated cells: 85.2;Fibro-adipogenic progenitors: 217.0;Fibroblasts: 202.6;Hepatic stellate cells: 542.2;Leydig cells: 166.4;Myosatellite cells: 174.3;Peritubular myoid cells: 99.2" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 217.0;Fibroblasts: 202.6;Stellate cells: 542.2;Stem cells: 174.3;Stromal cells: 229.0" "Cell type enhanced" "Detected in many" "ependymal cell: 93.3;fibroblast: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 229.7" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 36006642.1" "Tissue enhanced" "Detected in many" "skin: 190170479.0" HPA030769 Approved Approved Vesicles "Secreted to extracellular matrix" Other No No 12000000 "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 8 Vesicles "HPA030769: " "unprognostic (3.27e-2)" "unprognostic (2.04e-1)" "unprognostic (2.29e-1)" "unprognostic (5.10e-3)" "unprognostic (2.91e-2)" "unprognostic (2.38e-1)" "unprognostic (1.22e-2)" "unprognostic (7.55e-3)" "unprognostic (7.57e-2)" "unprognostic (3.30e-3)" "unprognostic (1.03e-3)" "unprognostic (2.42e-2)" "potential prognostic unfavorable (1.08e-6)" "unprognostic (8.84e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-3)" "unprognostic (4.38e-3)" "unprognostic (1.06e-2)" "unprognostic (3.73e-1)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (2.03e-2)" "unprognostic (2.10e-1)" "unprognostic (2.70e-1)" "unprognostic (3.58e-1)" "unprognostic (8.13e-3)" "unprognostic (1.59e-2)" "unprognostic (4.27e-3)" "unprognostic (6.34e-2)" "unprognostic (8.02e-3)" "unprognostic (1.44e-1)" COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Decidual stromal cells: 1279.3;Endometrial stromal cells: 498.8;Fibro-adipogenic progenitors: 384.4;Fibroblasts: 1238.3;Hepatic stellate cells: 916.6;Leydig cells: 746.7;Ovarian stromal cells: 425.3;Pericytes: 723.9;Peritubular myoid cells: 543.3;Smooth muscle cells: 797.3;Vascular smooth muscle cells: 502.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 1238.3;Leydig cells: 746.7;Mural cells: 723.9;Smooth muscle cells: 797.3;Stellate cells: 916.6;Stromal cells: 1279.3" "Group enriched" "Detected in many" 9 "ependymal cell: 95.5;fibroblast: 301.2;pericyte: 243.9;vascular associated smooth muscle cell: 256.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cancer enhanced" "Detected in many" "Brain cancer: 574.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 64.8" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "skin: 4190545550.2" "HPA007029, HPA030920, HPA038799" Enhanced Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" "Cell adhesion" NA NA 8700000 "Cluster 1: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: , HPA030920: , HPA038799: " "unprognostic (6.73e-2)" "unprognostic (2.43e-1)" "unprognostic (5.51e-2)" "unprognostic (5.87e-3)" "unprognostic (1.44e-1)" "unprognostic (2.56e-1)" "unprognostic (3.76e-2)" "unprognostic (1.66e-3)" "unprognostic (2.05e-1)" "unprognostic (2.63e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (2.49e-1)" "unprognostic (9.53e-3)" "unprognostic (2.08e-2)" "unprognostic (2.58e-2)" "unprognostic (1.23e-1)" "unprognostic (1.96e-1)" "unprognostic (6.79e-3)" "unprognostic (1.14e-1)" "unprognostic (5.00e-2)" "unprognostic (2.19e-1)" "unprognostic (1.75e-1)" "unprognostic (8.50e-2)" "unprognostic (5.62e-3)" "unprognostic (2.26e-2)" "unprognostic (2.49e-2)" "unprognostic (1.06e-1)" "unprognostic (5.15e-3)" "unprognostic (4.34e-2)" COL7A1 "EBD1, EBDCT, EBR1" ENSG00000114270 "Collagen type VII alpha 1 chain" Q02388 3 48564073-48595329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Protease inhibitor, Serine protease inhibitor" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 92.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 82.7;Basal prostatic cells: 64.3;Endometrial stromal cells: 46.8;Epididymal basal cells: 108.0;Medullary thymic epithelial cells: 36.0;Ocular epithelial cells: 34.5;Podocytes: 51.4;Respiratory basal cells: 50.1;Salivary basal cells: 37.0" "Cell type enhanced" "Detected in many" "Basal cells: 108.0;Renal nephron cells: 51.4;Stromal cells: 46.8" "Cell type enhanced" "Detected in many" "fibroblast: 64.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 47.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary gland basal cells" "Group enriched" "Detected in many" "Keratinocytes: 149181731.2;Large ducts: 37529313.4" "Group enriched" "Detected in some" "blood vessel: 2162760.7;fallopian tube: 1629645.0;lymphoid tissue: 4208412.9;skin: 5720977.8" "CAB016357, HPA018877, HPA042420" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to extracellular matrix" "Cell adhesion" NA NA "Cluster 58: Skin - Keratinization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 26: Keratinocytes - Keratinization" 6 "Endoplasmic reticulum" Vesicles "CAB016357: , HPA018877: , HPA042420: " "unprognostic (3.17e-2)" "unprognostic (1.38e-1)" "unprognostic (4.52e-3)" "unprognostic (1.29e-1)" "unprognostic (1.13e-1)" "unprognostic (2.39e-2)" "unprognostic (6.18e-2)" "unprognostic (7.16e-3)" "unprognostic (6.96e-2)" "unprognostic (7.83e-3)" "unprognostic (1.85e-2)" "unprognostic (7.75e-2)" "unprognostic (4.26e-1)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (6.66e-3)" "unprognostic (1.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.66e-1)" "unprognostic (1.05e-1)" "validated prognostic unfavorable (1.55e-4)" "validated prognostic unfavorable (2.78e-4)" "unprognostic (1.78e-2)" "unprognostic (1.27e-1)" "unprognostic (5.35e-2)" "unprognostic (4.50e-2)" "unprognostic (1.89e-1)" "unprognostic (1.36e-1)" "unprognostic (2.71e-1)" "unprognostic (2.31e-1)" COLGALT1 "FLJ22329, GLT25D1" ENSG00000130309 "Collagen beta(1-O)galactosyltransferase 1" Q8NBJ5 19 17555649-17583162 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 109.3;Hofbauer cells: 120.5;Kupffer cells: 93.3;Macrophages: 96.8;monocytes: 100.6;pDCs: 76.7" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 120.5;Trophoblast cells: 109.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 23.3;eosinophil: 11.2;intermediate monocyte: 26.6;myeloid DC: 17.1;non-classical monocyte: 19.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 170874762.3" "Tissue enhanced" "Detected in all" "lymphoid tissue: 47149047.4" "HPA047821, HPA048254" Approved Approved "Golgi apparatus,Vesicles" "Intracellular and membrane" Enzyme No No 6300 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 23: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 16 Vesicles "Golgi apparatus" "HPA047821: , HPA048254: " "unprognostic (1.72e-1)" "unprognostic (7.48e-2)" "unprognostic (2.36e-3)" "unprognostic (7.97e-2)" "unprognostic (1.05e-2)" "unprognostic (8.32e-2)" "unprognostic (2.90e-2)" "unprognostic (5.59e-2)" "unprognostic (5.39e-2)" "unprognostic (2.17e-3)" "unprognostic (2.76e-3)" "unprognostic (5.49e-2)" "unprognostic (1.91e-3)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (1.71e-2)" "unprognostic (2.83e-1)" "unprognostic (3.87e-2)" "unprognostic (1.61e-2)" "unprognostic (4.08e-1)" "unprognostic (8.77e-3)" "unprognostic (2.85e-2)" "unprognostic (1.54e-1)" "unprognostic (3.50e-1)" "unprognostic (4.69e-2)" "unprognostic (1.17e-1)" "unprognostic (6.33e-2)" "unprognostic (2.09e-1)" "unprognostic (2.98e-2)" "unprognostic (1.09e-1)" COMMD2 HSPC042 ENSG00000114744 "COMM domain containing 2" Q86X83 3 149738472-149752495 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA044190, HPA075248" Uncertain Uncertain Vesicles NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 85 Vesicles "HPA044190: , HPA075248: " "unprognostic (1.17e-1)" "unprognostic (1.17e-1)" "unprognostic (2.05e-1)" "unprognostic (7.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.24e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (5.56e-3)" "unprognostic (1.22e-1)" "unprognostic (2.62e-2)" "potential prognostic favorable (4.80e-6)" "unprognostic (1.37e-3)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (3.36e-3)" "unprognostic (3.35e-1)" "unprognostic (1.47e-1)" "unprognostic (4.59e-2)" "unprognostic (1.31e-1)" "unprognostic (4.22e-1)" "potential prognostic unfavorable (4.50e-4)" "validated prognostic unfavorable (7.48e-4)" "validated prognostic unfavorable (4.59e-4)" "unprognostic (6.92e-2)" "unprognostic (1.39e-1)" "unprognostic (1.03e-2)" "unprognostic (8.62e-3)" "unprognostic (1.87e-1)" "unprognostic (1.16e-1)" "unprognostic (9.02e-2)" "unprognostic (2.17e-1)" COMP "EDM1, EPD1, MED, PSACH, THBS5" ENSG00000105664 "Cartilage oligomeric matrix protein" P49747 19 18782773-18791305 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Cell adhesion" Heparin-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "blood vessel: 333.9" "Cell type enhanced" "Detected in some" "Early spermatids: 35.2;Endometrial glandular cells: 61.6;Epididymal basal cells: 205.9;Epididymal principal cells: 21.2;Fibroblasts: 76.4;Late primary spermatocytes: 56.7;Late spermatids: 148.5" "Group enriched" "Detected in many" 5 "Basal cells: 205.9;Fibroblasts: 76.4;Glandular cells: 61.6;Spermatogenic cell types: 148.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 109.9" "Region enhanced" "Detected in single" "cerebellum: 2.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Bladder cancer: 6.7;Gastric cancer: 4.2;ovarian cancer: 12.3;Rhabdoid: 5.1" "Spleen - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in some" 7 "Smooth muscle cells: 82820219.7" "Tissue enriched" "Detected in some" "blood vessel: 152172542.8" HPA077555 Approved "Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" NA NA 1400000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 35: Non-specific - DNA binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 7 "Golgi apparatus" "HPA077555: " "unprognostic (2.18e-3)" "unprognostic (1.31e-1)" "unprognostic (1.98e-1)" "unprognostic (1.11e-1)" "unprognostic (1.62e-3)" "unprognostic (7.62e-2)" "unprognostic (6.29e-2)" "unprognostic (1.30e-2)" "unprognostic (3.35e-1)" "unprognostic (4.74e-3)" "unprognostic (3.05e-2)" "unprognostic (2.62e-1)" "unprognostic (1.22e-2)" "unprognostic (6.06e-2)" "unprognostic (6.09e-2)" "unprognostic (4.88e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.77e-2)" "unprognostic (1.52e-2)" "unprognostic (1.85e-2)" "unprognostic (4.96e-3)" "unprognostic (1.16e-1)" "unprognostic (1.85e-2)" "unprognostic (8.00e-2)" COPE epsilon-COP ENSG00000105669 "COPI coat complex subunit epsilon" O14579 19 18899514-18919387 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1002.6;Oocytes: 810.5;Syncytiotrophoblasts: 668.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1002.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 66707317.1" "Low tissue specificity" "Detected in all" "CAB034345, HPA041605, HPA043576" Supported Enhanced "Golgi apparatus" NA NA 82000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 155 "Golgi apparatus" "CAB034345: , HPA041605: , HPA043576: " "unprognostic (1.46e-1)" "unprognostic (2.91e-1)" "unprognostic (3.56e-1)" "unprognostic (2.25e-2)" "unprognostic (2.69e-1)" "unprognostic (4.86e-2)" "unprognostic (1.51e-1)" "unprognostic (2.79e-1)" "unprognostic (2.59e-2)" "unprognostic (9.32e-2)" "unprognostic (1.70e-1)" "unprognostic (5.37e-2)" "unprognostic (1.30e-2)" "unprognostic (1.92e-3)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (1.78e-1)" "unprognostic (2.76e-1)" "unprognostic (1.28e-1)" "unprognostic (2.23e-1)" "unprognostic (2.34e-1)" "unprognostic (2.57e-1)" "unprognostic (5.01e-3)" "unprognostic (3.30e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (4.52e-2)" "unprognostic (2.28e-1)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "unprognostic (6.44e-2)" "potential prognostic favorable (4.77e-4)" COPG1 COPG ENSG00000181789 "COPI coat complex subunit gamma 1" Q9Y678 3 129249606-129277773 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 153459714.4" "Low tissue specificity" "Detected in all" "HPA037866, HPA037867, HPA045712" Supported Supported "Nucleoplasm,Golgi apparatus,Cytosol" No No 150000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 77 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA037866: , HPA037867: , HPA045712: " "unprognostic (1.63e-1)" "unprognostic (4.09e-2)" "unprognostic (2.74e-1)" "unprognostic (6.62e-2)" "unprognostic (6.65e-3)" "unprognostic (3.11e-1)" "unprognostic (2.82e-1)" "unprognostic (6.18e-3)" "unprognostic (3.35e-3)" "validated prognostic unfavorable (5.03e-4)" "validated prognostic unfavorable (6.79e-4)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.20e-6)" "unprognostic (1.11e-2)" "unprognostic (8.53e-3)" "unprognostic (2.36e-1)" "unprognostic (4.66e-1)" "unprognostic (1.72e-1)" "unprognostic (1.96e-1)" "unprognostic (1.04e-2)" "unprognostic (6.22e-2)" "unprognostic (1.98e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-1)" "unprognostic (2.30e-1)" "unprognostic (3.07e-1)" "unprognostic (1.95e-1)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" COPS2 "ALIEN, CSN2, TRIP15" ENSG00000166200 "COP9 signalosome subunit 2" P61201 15 49106068-49155661 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 55555421.6" "HPA016867, HPA018271, HPA061071" Approved Supported "Vesicles,Cytokinetic bridge" Yes No 250000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 80 Vesicles "Cytokinetic bridge" "HPA016867: , HPA018271: , HPA061071: " "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.62e-1)" "unprognostic (9.94e-2)" "unprognostic (3.55e-1)" "unprognostic (2.37e-1)" "unprognostic (4.10e-3)" "unprognostic (3.36e-3)" "validated prognostic favorable (8.53e-8)" "validated prognostic favorable (4.81e-5)" "unprognostic (1.79e-2)" "unprognostic (6.18e-2)" "unprognostic (4.99e-3)" "unprognostic (3.36e-3)" "unprognostic (4.21e-3)" "unprognostic (2.47e-1)" "unprognostic (2.38e-1)" "unprognostic (7.50e-2)" "unprognostic (4.13e-2)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (1.38e-2)" "unprognostic (7.95e-2)" "unprognostic (9.99e-2)" "unprognostic (2.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (1.59e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" COPS4 "CSN4, SGN4" ENSG00000138663 "COP9 signalosome subunit 4" Q9BT78 4 83034447-83075818 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 272.2;Oocytes: 184.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 272.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA036894, HPA042828" Approved Supported "Nuclear speckles" NA NA 260000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 86 "Nuclear speckles" "HPA036894: , HPA042828: " "unprognostic (3.23e-1)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (5.32e-3)" "unprognostic (3.07e-1)" "potential prognostic favorable (3.77e-4)" "unprognostic (2.57e-1)" "unprognostic (1.50e-1)" "unprognostic (5.44e-2)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "validated prognostic favorable (3.01e-9)" "validated prognostic favorable (9.64e-6)" "unprognostic (7.70e-3)" "potential prognostic unfavorable (2.74e-4)" "unprognostic (1.75e-1)" "unprognostic (5.02e-2)" "unprognostic (4.72e-1)" "unprognostic (2.49e-1)" "unprognostic (2.02e-2)" "unprognostic (1.54e-1)" "unprognostic (6.81e-3)" "unprognostic (1.65e-1)" "unprognostic (9.19e-2)" "unprognostic (4.85e-2)" "unprognostic (1.56e-3)" "unprognostic (2.49e-1)" "unprognostic (4.40e-1)" "unprognostic (5.93e-2)" "unprognostic (2.53e-1)" "unprognostic (2.15e-1)" "unprognostic (1.81e-2)" COQ3 bA9819.1 ENSG00000132423 "Coenzyme Q3, methyltransferase" Q9NZJ6 6 99369401-99394195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubiquinone biosynthesis" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 47.7" "Cell type enhanced" "Detected in many" "Myonuclei: 35.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8199939.3;Skeletal myofibers: 10167997.5" "Tissue enhanced" "Detected in all" "heart muscle: 96942545.4" "HPA031273, HPA031274" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 52: Non-specific - Cellular respiration" "Cluster 31: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 14 Nucleoplasm Mitochondria "HPA031273: , HPA031274: " "unprognostic (5.92e-3)" "unprognostic (3.10e-3)" "unprognostic (1.63e-2)" "unprognostic (1.94e-2)" "unprognostic (8.49e-2)" "potential prognostic favorable (2.90e-4)" "unprognostic (7.37e-2)" "unprognostic (5.16e-2)" "unprognostic (4.69e-2)" "unprognostic (9.62e-3)" "unprognostic (3.25e-3)" "unprognostic (7.32e-3)" "unprognostic (1.31e-2)" "unprognostic (1.44e-3)" "unprognostic (2.61e-2)" "unprognostic (3.43e-3)" "unprognostic (9.81e-2)" "unprognostic (9.54e-3)" "unprognostic (5.68e-3)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (9.15e-2)" "unprognostic (1.13e-1)" "unprognostic (1.89e-1)" "unprognostic (1.36e-2)" "unprognostic (5.18e-2)" "unprognostic (1.25e-1)" "unprognostic (7.76e-2)" "unprognostic (9.13e-2)" "unprognostic (8.96e-2)" "unprognostic (2.13e-2)" CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" Cardiomyopathy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "heart muscle: 53.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 975.7" "Cell type enriched" "Detected in many" 4 "Myocytes: 975.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine cancer: 1.1" "Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Fibroblasts_2" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 1389 "Capillaries: 218716.2;Cardiomyocytes: 59178.2" "Not detected" "Not detected" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Enzyme Yes No "Cluster 35: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: " "unprognostic (4.37e-2)" "unprognostic (1.98e-1)" "unprognostic (1.82e-2)" "unprognostic (5.53e-2)" "unprognostic (1.31e-1)" "unprognostic (4.61e-2)" "unprognostic (1.04e-2)" "unprognostic (1.32e-1)" "unprognostic (5.67e-3)" "unprognostic (1.02e-1)" "unprognostic (3.24e-1)" "unprognostic (4.08e-2)" "unprognostic (2.06e-3)" CORO1A "coronin-1, HCORO1, p57" ENSG00000102879 "Coronin 1A" P31146 16 30182827-30189076 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 525.4;lymphoid tissue: 544.1" "Cell type enhanced" "Detected in many" "B-cells: 201.6;cDC: 203.1;Hofbauer cells: 438.6;Innate lymphoid cells: 103.9;Macrophages: 109.8;Megakaryocytes: 265.8;Monocyte progenitors: 212.8;monocytes: 266.7;Neutrophil progenitors: 239.4;Neutrophils: 377.8;NK-cells: 287.5;pDCs: 261.4;Plasma cells: 131.5;T-cells: 281.8" "Cell type enhanced" "Detected in many" "B-cells: 201.6;dendritic cells: 261.4;Megakaryocytes: 265.8;Mononuclear phagocytes: 438.6;Neutrophils: 377.8;NK-cells: 287.5;T-cells: 281.8" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 44.4;leukocyte: 151.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 25 "Leukemia: 547.2;lymphoma: 754.1;Myeloma: 427.8" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Skeletal muscle - Macrophages, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 642128909.4;T-cells: 837717643.1" "Tissue enhanced" "Detected in all" "lymphoid tissue: 787802333.3" "CAB046473, HPA051132" Enhanced Approved Cytosol NA NA 42000000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 35 Cytosol "CAB046473: , HPA051132: " "unprognostic (1.44e-1)" "unprognostic (1.07e-3)" "unprognostic (1.55e-2)" "unprognostic (6.44e-3)" "unprognostic (5.82e-2)" "unprognostic (1.40e-1)" "unprognostic (9.00e-3)" "unprognostic (5.91e-2)" "potential prognostic favorable (6.02e-5)" "unprognostic (3.41e-1)" "unprognostic (2.58e-2)" "unprognostic (1.45e-1)" "unprognostic (9.58e-2)" "unprognostic (7.84e-2)" "unprognostic (4.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.82e-1)" "unprognostic (2.70e-1)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (6.22e-2)" "unprognostic (9.80e-2)" "unprognostic (1.69e-3)" "unprognostic (2.10e-1)" "unprognostic (2.17e-2)" "unprognostic (5.59e-2)" "potential prognostic favorable (9.01e-5)" "unprognostic (2.07e-1)" "unprognostic (3.75e-3)" "unprognostic (9.89e-2)" "unprognostic (1.20e-1)" CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.0" "Cell type enhanced" "Detected in many" "Enterocytes: 242.6;Foveolar cells: 128.8;Neutrophil progenitors: 182.1;Papillary tip epithelial cells: 146.8;Prostatic hillock cells: 217.6;Sertoli cells: 207.2;Somatotrophs: 153.6" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 217.6;Enterocytes: 242.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 3013894.5;Granulosa cells: 3222675.7;Microglia and Neuropil: 2662759.1" "Group enriched" "Detected in many" "cerebral cortex: 2002822.6;intestine: 3615592.6;lung: 2627399.0" "HPA041161, HPA041302" Enhanced Approved "Vesicles,Plasma membrane,Basal body,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 11 "Plasma membrane, Cytosol" "Vesicles, Basal body" "HPA041161: , HPA041302: " "unprognostic (7.39e-2)" "unprognostic (3.05e-3)" "unprognostic (1.22e-1)" "unprognostic (3.73e-1)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (8.18e-2)" "unprognostic (1.64e-1)" "unprognostic (5.30e-1)" "unprognostic (1.86e-2)" "unprognostic (5.57e-2)" "unprognostic (3.47e-3)" "unprognostic (3.92e-2)" "unprognostic (7.41e-2)" "unprognostic (2.76e-1)" "unprognostic (8.25e-2)" "unprognostic (1.55e-1)" "unprognostic (8.31e-3)" "potential prognostic unfavorable (4.47e-4)" "unprognostic (7.70e-2)" "unprognostic (3.54e-1)" "unprognostic (1.80e-1)" "unprognostic (1.30e-2)" "unprognostic (5.02e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" "unprognostic (4.04e-2)" "unprognostic (1.52e-1)" COX4I1 "COX4, COX4-1, COXIV, COXIV-1" ENSG00000131143 "Cytochrome c oxidase subunit 4I1" P13073 16 85798633-85807068 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Colonocytes: 2801.3;Enterocytes: 3310.7;Esophageal apical cells: 2869.8;Esophageal basal cells: 2552.8;Esophageal suprabasal cells: 3208.9;Parietal cells: 4069.7" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 4069.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2165142814.4" "Tissue enhanced" "Detected in all" "heart muscle: 865732747.9" "HPA002485, CAB004080, HPA070836" Supported Supported Mitochondria NA NA 46000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 115 Mitochondria "CAB004080: , HPA002485: , HPA070836: " "unprognostic (1.49e-2)" "unprognostic (8.28e-2)" "unprognostic (2.77e-1)" "unprognostic (8.22e-3)" "unprognostic (2.26e-1)" "unprognostic (2.44e-2)" "unprognostic (2.82e-1)" "unprognostic (2.35e-2)" "unprognostic (1.18e-2)" "unprognostic (3.27e-2)" "unprognostic (3.08e-2)" "unprognostic (8.61e-3)" "unprognostic (2.69e-3)" "unprognostic (9.38e-2)" "unprognostic (2.94e-1)" "unprognostic (1.30e-1)" "unprognostic (3.12e-2)" "unprognostic (3.45e-2)" "unprognostic (2.46e-1)" "unprognostic (3.88e-2)" "unprognostic (4.65e-1)" "unprognostic (3.35e-2)" "unprognostic (1.04e-1)" "unprognostic (3.45e-1)" "unprognostic (2.10e-1)" "unprognostic (1.34e-1)" "unprognostic (3.96e-1)" "unprognostic (3.69e-2)" "unprognostic (1.50e-1)" "unprognostic (2.35e-1)" "unprognostic (2.31e-1)" COX5B ENSG00000135940 "Cytochrome c oxidase subunit 5B" P10606 2 97646062-97648383 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1143.7;skeletal muscle: 1249.4" "Cell type enhanced" "Detected in all" "Colonocytes: 2717.1;Enteric transient amplifying cells: 1750.3;Enterocytes: 2408.2;Esophageal apical cells: 1740.3;Esophageal suprabasal cells: 2249.9;Parietal cells: 3679.0" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 3679.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1211547156.9" "Tissue enriched" "Detected in all" "heart muscle: 3696370531.4" HPA034517 Supported Enhanced Mitochondria,Acrosome NA NA 370000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 39 Mitochondria Acrosome "HPA034517: " "unprognostic (5.84e-2)" "unprognostic (1.55e-1)" "unprognostic (2.01e-1)" "unprognostic (2.10e-2)" "unprognostic (3.21e-1)" "unprognostic (1.50e-1)" "unprognostic (2.28e-1)" "unprognostic (3.73e-1)" "unprognostic (1.88e-3)" "unprognostic (9.83e-3)" "unprognostic (1.50e-2)" "unprognostic (1.90e-1)" "unprognostic (2.32e-2)" "unprognostic (3.19e-1)" "unprognostic (1.69e-2)" "unprognostic (3.39e-3)" "unprognostic (1.93e-1)" "unprognostic (3.54e-1)" "unprognostic (4.87e-2)" "unprognostic (3.95e-2)" "unprognostic (2.28e-1)" "unprognostic (3.01e-2)" "unprognostic (3.46e-1)" "unprognostic (9.85e-2)" "unprognostic (7.46e-2)" "unprognostic (5.23e-2)" "unprognostic (7.16e-2)" "unprognostic (6.43e-2)" "unprognostic (1.52e-1)" "unprognostic (1.73e-1)" "unprognostic (3.81e-2)" COX6A1 "COX6A, COX6AL" ENSG00000111775 "Cytochrome c oxidase subunit 6A1" P12074 12 120438090-120440737 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Charcot-Marie-Tooth disease, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1831.8" "Cell type enhanced" "Detected in many" "Colonocytes: 295.8;Enteric stem cells: 169.5;Enteric transient amplifying cells: 240.1;Enterocytes: 443.9;Epididymal efferent duct ciliated cells: 145.2;Gastric chief cells: 170.4;Parietal cells: 910.5" "Cell type enhanced" "Detected in many" "Enterocytes: 443.9;Gastric glandular cells: 910.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 62334455.5;Large ducts: 78035762.1" "Low tissue specificity" "Detected in many" HPA062394 Approved Supported "Mitochondria,Principal piece" NA NA 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 4 Mitochondria "Principal piece" "HPA062394: " "unprognostic (8.09e-3)" "unprognostic (9.88e-2)" "unprognostic (3.54e-1)" "unprognostic (5.31e-3)" "potential prognostic favorable (6.23e-4)" "unprognostic (5.75e-2)" "unprognostic (1.91e-1)" "unprognostic (1.16e-1)" "unprognostic (9.85e-3)" "unprognostic (1.08e-1)" "unprognostic (8.83e-2)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (1.07e-3)" "unprognostic (2.68e-2)" "unprognostic (2.08e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (1.49e-2)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (6.10e-2)" "unprognostic (3.74e-1)" "unprognostic (2.65e-1)" "unprognostic (1.26e-1)" "unprognostic (4.73e-2)" "unprognostic (1.35e-1)" "unprognostic (1.80e-1)" "unprognostic (1.98e-1)" "unprognostic (6.43e-2)" COX6B1 "COX6B, COXG" ENSG00000126267 "Cytochrome c oxidase subunit 6B1" P14854 19 35648323-35658782 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 2287.9" "Cell type enhanced" "Detected in many" "Colonocytes: 1932.4;Enterocytes: 1982.1;Esophageal apical cells: 3024.0;Esophageal suprabasal cells: 2038.1;Parietal cells: 3587.1" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 3024.0;Gastric glandular cells: 3587.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 271854057.4" "Tissue enriched" "Detected in all" "heart muscle: 2173873101.4" HPA004192 Supported Supported "Mitochondria,Principal piece" NA NA 75000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 8 Mitochondria "Principal piece" "HPA004192: " "unprognostic (1.74e-2)" "unprognostic (2.22e-1)" "unprognostic (8.77e-2)" "unprognostic (1.04e-3)" "unprognostic (1.31e-3)" "unprognostic (1.47e-1)" "unprognostic (2.99e-2)" "unprognostic (2.75e-1)" "unprognostic (1.44e-1)" "unprognostic (2.73e-3)" "unprognostic (1.66e-2)" "unprognostic (2.52e-3)" "unprognostic (1.94e-1)" "unprognostic (1.17e-1)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (7.27e-4)" "unprognostic (9.54e-2)" "unprognostic (2.27e-2)" "unprognostic (3.26e-1)" "unprognostic (1.83e-1)" "unprognostic (2.53e-2)" "unprognostic (7.90e-2)" "unprognostic (1.43e-1)" "unprognostic (1.51e-1)" "unprognostic (1.97e-1)" "unprognostic (9.40e-2)" "unprognostic (3.49e-1)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.32e-1)" "unprognostic (2.60e-1)" COX6B2 "COXVIB2, CT59, FLJ32865" ENSG00000160471 "Cytochrome c oxidase subunit 6B2" Q6YFQ2 19 55349306-55354719 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "testis: 87.4" "Cell type enhanced" "Detected in some" "Colonocytes: 7.9;Early primary spermatocytes: 27.6;Early spermatids: 13.2;Late primary spermatocytes: 65.2;Respiratory deuterosomal cells: 6.2" "Cell type enriched" "Detected in many" 8 "Spermatogenic cell types: 65.2" "Cell type enhanced" "Detected in some" "ependymal cell: 3.3" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 12.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA035014 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "Nucleoplasm, Plasma membrane, Cytosol" "HPA035014: " "unprognostic (9.00e-3)" "unprognostic (5.72e-2)" "unprognostic (6.78e-2)" "unprognostic (2.40e-1)" "unprognostic (1.77e-1)" "unprognostic (2.72e-2)" "unprognostic (1.75e-2)" "unprognostic (4.64e-3)" "unprognostic (2.40e-3)" "unprognostic (1.14e-1)" "unprognostic (5.56e-2)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (4.76e-2)" "unprognostic (2.65e-2)" "unprognostic (2.51e-2)" "unprognostic (8.55e-2)" "unprognostic (9.35e-2)" "unprognostic (1.33e-2)" COX6C ENSG00000164919 "Cytochrome c oxidase subunit 6C" P09669 8 99873200-99893707 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 2066.0;Hepatocytes: 2106.9;Parietal cells: 5086.2;Syncytiotrophoblasts: 2329.3" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 5086.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 636.0" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 773681982.9" "Tissue enhanced" "Detected in all" "heart muscle: 425849431.3" "HPA014295, CAB016244" Enhanced Enhanced Mitochondria NA NA 67000 "Cluster 6: T-cells - T-cell receptor" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 19 Mitochondria "CAB016244: , HPA014295: " "unprognostic (2.43e-1)" "unprognostic (2.01e-1)" "unprognostic (6.93e-2)" "unprognostic (2.13e-1)" "unprognostic (3.60e-2)" "unprognostic (2.72e-1)" "unprognostic (3.76e-1)" "unprognostic (8.15e-3)" "unprognostic (7.02e-2)" "unprognostic (2.46e-2)" "unprognostic (1.09e-2)" "unprognostic (4.54e-3)" "unprognostic (7.44e-2)" "unprognostic (5.56e-3)" "unprognostic (1.55e-3)" "unprognostic (9.83e-2)" "unprognostic (1.13e-1)" "unprognostic (3.22e-3)" "unprognostic (1.90e-1)" "unprognostic (4.01e-3)" "unprognostic (3.48e-2)" "unprognostic (4.00e-2)" "unprognostic (8.47e-3)" "unprognostic (8.91e-2)" "unprognostic (7.84e-2)" "unprognostic (3.41e-2)" "unprognostic (9.99e-3)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.81e-2)" "unprognostic (2.70e-2)" COX7A2L "COX7AR, COX7RP, EB1, SCAF1, SCAFI, SIG81" ENSG00000115944 "Cytochrome c oxidase subunit 7A2 like" O14548 2 42333546-42425088 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 805.9;Parietal cells: 735.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 63620032.8" "Group enriched" "Detected in many" "cerebral cortex: 8271115.4;heart muscle: 5350822.0;intestine: 8118903.2" "HPA059124, CAB073545" Enhanced Nucleoli,Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 25: Non-specific - Ribosome" "Cluster 97: Non-specific - Cellular respiration" 7 Mitochondria Nucleoli "CAB073545: , HPA059124: " "unprognostic (2.12e-2)" "unprognostic (1.98e-3)" "unprognostic (2.84e-3)" "unprognostic (1.21e-1)" "unprognostic (2.37e-2)" "unprognostic (8.51e-2)" "unprognostic (1.32e-1)" "unprognostic (3.42e-1)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (1.10e-1)" "potential prognostic favorable (1.75e-8)" "unprognostic (4.38e-2)" "unprognostic (4.40e-3)" "validated prognostic unfavorable (4.91e-5)" "validated prognostic unfavorable (2.85e-4)" "unprognostic (1.43e-1)" "unprognostic (1.05e-1)" "unprognostic (3.81e-2)" "unprognostic (1.20e-1)" "unprognostic (7.79e-2)" "unprognostic (3.99e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (3.10e-2)" "unprognostic (1.23e-2)" "unprognostic (3.73e-2)" "unprognostic (2.77e-1)" "unprognostic (5.17e-2)" "unprognostic (2.86e-1)" "unprognostic (1.91e-2)" "unprognostic (1.28e-1)" CPEB1 "CPEB, FLJ13203" ENSG00000214575 "Cytoplasmic polyadenylation element binding protein 1" Q9BZB8 15 82543201-82648861 "Predicted intracellular proteins" "mRNA processing, Translation regulation" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.6;testis: 30.4" "Cell type enhanced" "Detected in some" "Astrocytes: 24.9;Brain excitatory neurons: 27.7;Brain inhibitory neurons: 21.7;Choroid plexus epithelial cells: 102.3;Ependymal cells: 68.5;Late spermatids: 22.4;Oligodendrocytes: 156.8;Other brain neurons: 39.5;Podocytes: 44.7" "Cell type enhanced" "Detected in some" "Ciliated cells: 102.3;Glial cells: 156.8;Neuronal cells: 39.5;Renal nephron cells: 44.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 238.9" "Cancer enriched" "Detected in many" 7 "Testicular Germ Cell Tumor (TCGA): 61.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Oocytes: 18660888.1" "Tissue enriched" "Detected in single" 197 "lymphoid tissue: 19663.5" HPA040396 Supported Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" 13 "Nucleoplasm, Cytosol" "HPA040396: " "unprognostic (2.43e-1)" "unprognostic (5.32e-3)" "unprognostic (2.22e-1)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (6.65e-6)" "unprognostic (6.13e-3)" "unprognostic (4.08e-1)" "unprognostic (5.88e-2)" "unprognostic (1.47e-1)" "unprognostic (2.37e-1)" "unprognostic (3.24e-3)" "unprognostic (8.15e-2)" "unprognostic (3.88e-2)" "unprognostic (1.31e-1)" "unprognostic (6.72e-3)" "unprognostic (7.52e-2)" "unprognostic (1.73e-1)" CPEB2 ENSG00000137449 "Cytoplasmic polyadenylation element binding protein 2" Q7Z5Q1 4 15002481-15070153 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 369.5;Melanocytes: 436.8;Neutrophil progenitors: 260.3;Neutrophils: 369.3;Ocular epithelial cells: 277.4;Oligodendrocytes: 397.7" "Cell type enhanced" "Detected in all" "Glial cells: 397.7;Neutrophils: 369.3;Pigment cells: 436.8;Renal nephron cells: 369.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 1866803.9" "Tissue enriched" "Detected in single" 50859 "cerebral cortex: 5085930.2" HPA072513 Approved Cytosol Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 100: Stratified epithelial cells - Barrier functions" 2 Cytosol "HPA072513: " "unprognostic (1.06e-1)" "unprognostic (8.97e-2)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (8.00e-5)" "unprognostic (1.23e-1)" "unprognostic (3.13e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (8.06e-2)" "unprognostic (5.67e-2)" "unprognostic (5.50e-3)" "unprognostic (9.77e-2)" "unprognostic (4.96e-2)" "unprognostic (6.96e-3)" "unprognostic (2.06e-2)" "unprognostic (1.83e-2)" "unprognostic (2.35e-1)" "unprognostic (1.40e-1)" "unprognostic (4.29e-1)" "unprognostic (1.32e-1)" "unprognostic (4.56e-2)" "unprognostic (1.43e-2)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (2.32e-1)" "unprognostic (1.20e-1)" "unprognostic (3.17e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (4.48e-2)" "unprognostic (5.91e-2)" CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 660.5;Late spermatids: 710.3;Retinal ganglion cells: 648.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 710.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Myeloma: 4.5" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 4341896.2" "Tissue enriched" "Detected in single" 60140 "cerebral cortex: 6014006.9" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "potential prognostic favorable (6.76e-4)" "unprognostic (1.80e-1)" "unprognostic (2.72e-1)" "unprognostic (5.22e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (1.27e-1)" "potential prognostic favorable (9.86e-4)" "potential prognostic favorable (1.94e-4)" "unprognostic (5.92e-2)" "validated prognostic favorable (3.41e-5)" "validated prognostic favorable (3.44e-4)" "unprognostic (3.74e-3)" "validated prognostic favorable (3.16e-4)" "validated prognostic favorable (2.64e-6)" "unprognostic (3.47e-3)" "unprognostic (1.75e-2)" "unprognostic (4.80e-2)" "unprognostic (8.68e-2)" "unprognostic (3.97e-2)" "unprognostic (8.85e-2)" "unprognostic (3.39e-2)" "unprognostic (5.66e-2)" "unprognostic (2.50e-1)" "unprognostic (1.48e-1)" "unprognostic (1.20e-1)" "unprognostic (4.66e-2)" "unprognostic (6.69e-3)" "unprognostic (2.25e-1)" CPNE1 CPN1 ENSG00000214078 "Copine 1" Q99829 20 35626031-35664956 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA065876, HPA072634" Approved Supported "Nucleoplasm,Nuclear membrane" NA NA 520000 "Cluster 7: Non-specific - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 "Nucleoplasm, Nuclear membrane" "HPA065876: , HPA072634: " "unprognostic (3.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.26e-1)" "unprognostic (5.00e-2)" "unprognostic (5.63e-2)" "unprognostic (2.11e-1)" "unprognostic (1.34e-1)" "unprognostic (2.13e-1)" "unprognostic (1.37e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.11e-1)" "unprognostic (7.26e-3)" "unprognostic (1.36e-3)" "unprognostic (4.49e-3)" "unprognostic (1.14e-1)" "unprognostic (2.53e-2)" "unprognostic (5.26e-2)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "validated prognostic unfavorable (7.84e-4)" "validated prognostic unfavorable (3.48e-5)" "unprognostic (8.60e-3)" "unprognostic (2.88e-2)" "unprognostic (2.30e-2)" "unprognostic (7.19e-2)" "unprognostic (9.66e-2)" "unprognostic (5.68e-2)" "unprognostic (2.19e-1)" "unprognostic (7.69e-2)" CPOX "CPO, CPX, HCP" ENSG00000080819 "Coproporphyrinogen oxidase" P36551 3 98579446-98593648 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 52.8;Oligodendrocytes: 27.9" "Group enriched" "Detected in many" 4 "Erythrocytes: 52.8;Glial cells: 27.9" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Hepatocytes: 22953909.8;Oocytes: 59056696.6" "Tissue enhanced" "Detected in all" "bone marrow: 21390587.3" "HPA015736, HPA054448" Supported Mitochondria No No 160000 "Cluster 14: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 4 Mitochondria "HPA015736: , HPA054448: " "unprognostic (3.37e-1)" "unprognostic (5.62e-2)" "unprognostic (1.24e-2)" "unprognostic (4.53e-3)" "unprognostic (1.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.67e-1)" "unprognostic (1.53e-1)" "unprognostic (1.25e-1)" "unprognostic (1.02e-2)" "validated prognostic unfavorable (5.00e-4)" "validated prognostic unfavorable (6.77e-5)" "unprognostic (1.79e-1)" "unprognostic (2.25e-3)" "unprognostic (3.68e-2)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (6.52e-4)" "unprognostic (9.09e-3)" "unprognostic (2.37e-1)" "unprognostic (2.99e-1)" "unprognostic (5.01e-2)" "unprognostic (8.94e-3)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (2.03e-3)" "unprognostic (8.28e-3)" "unprognostic (3.15e-1)" "unprognostic (6.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.36e-2)" "unprognostic (5.10e-3)" "unprognostic (1.59e-1)" CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12803887 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Neutrophils: 1636.4" "Cell type enriched" "Detected in all" 4 "Neutrophils: 1636.4" "Cell type enhanced" "Detected in all" "pericyte: 169.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 676.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 13172169.6;Large ducts: 16171744.2;Proximal tubules: 13702818.4" "Low tissue specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" No No 580000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 49: HMC-1 - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 Cytosol "Plasma membrane" "HPA040938: , HPA041970: " "unprognostic (1.50e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (2.29e-1)" "unprognostic (1.03e-1)" "unprognostic (1.40e-2)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (3.11e-3)" "unprognostic (1.03e-1)" "unprognostic (2.59e-1)" "potential prognostic favorable (3.84e-9)" "unprognostic (7.26e-2)" "unprognostic (3.16e-1)" "unprognostic (3.29e-1)" "unprognostic (1.94e-1)" "unprognostic (6.75e-2)" "unprognostic (1.21e-1)" "unprognostic (8.34e-2)" "unprognostic (1.41e-1)" "unprognostic (1.41e-1)" "unprognostic (7.43e-3)" "unprognostic (3.06e-2)" "unprognostic (1.65e-1)" "unprognostic (4.10e-1)" "unprognostic (2.13e-1)" "unprognostic (2.83e-1)" "unprognostic (2.80e-1)" "unprognostic (9.30e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (4.54e-1)" CPSF1 CPSF160 ENSG00000071894 "Cleavage and polyadenylation specific factor 1" Q10570 8 144393229-144409335 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 53.9;Sertoli cells: 65.7" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 65.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "skeletal muscle: 11169272.8" "HPA065167, HPA068906" Supported Nucleoplasm No No "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 42 Nucleoplasm "HPA065167: , HPA068906: " "unprognostic (8.90e-2)" "unprognostic (1.51e-1)" "unprognostic (2.60e-1)" "unprognostic (6.50e-2)" "unprognostic (4.87e-2)" "unprognostic (6.44e-2)" "unprognostic (1.32e-1)" "unprognostic (1.05e-3)" "unprognostic (5.43e-2)" "unprognostic (6.56e-2)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (2.07e-1)" "unprognostic (7.12e-2)" "unprognostic (4.24e-3)" "unprognostic (5.47e-2)" "unprognostic (7.62e-2)" "unprognostic (2.37e-1)" "unprognostic (3.57e-2)" "unprognostic (6.79e-2)" "unprognostic (1.33e-1)" "unprognostic (2.93e-3)" "unprognostic (3.73e-2)" "unprognostic (3.52e-3)" "unprognostic (1.69e-1)" "unprognostic (6.95e-2)" "unprognostic (9.50e-2)" "unprognostic (1.09e-3)" "unprognostic (3.12e-1)" "unprognostic (4.73e-2)" "unprognostic (5.48e-2)" "unprognostic (3.25e-1)" CPSF6 "CFIM, CFIM68, CFIM72, HPBRII-4, HPBRII-7" ENSG00000111605 "Cleavage and polyadenylation specific factor 6" Q16630 12 69239569-69274358 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 49358665.4" "Tissue enhanced" "Detected in all" "lymphoid tissue: 41146921.6" HPA039973 Supported Enhanced "Nucleoplasm,Nuclear speckles" No No 230000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 318 "Nucleoplasm, Nuclear speckles" "HPA039973: " "unprognostic (3.54e-1)" "unprognostic (2.34e-1)" "unprognostic (2.71e-1)" "unprognostic (1.62e-2)" "unprognostic (2.58e-2)" "unprognostic (5.89e-2)" "unprognostic (8.11e-2)" "unprognostic (1.79e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (2.72e-6)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.18e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (1.19e-8)" "unprognostic (6.17e-3)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (4.51e-2)" "unprognostic (6.40e-2)" "unprognostic (4.95e-2)" "unprognostic (3.89e-1)" "unprognostic (8.13e-2)" "unprognostic (1.54e-3)" "unprognostic (7.72e-3)" "unprognostic (9.82e-2)" "unprognostic (4.54e-2)" "unprognostic (2.11e-2)" "unprognostic (3.43e-2)" "unprognostic (1.01e-1)" "unprognostic (1.65e-1)" "unprognostic (9.52e-2)" "unprognostic (1.04e-2)" CPT1A "CPT1, CPT1-L, L-CPT1" ENSG00000110090 "Carnitine palmitoyltransferase 1A" P50416 11 68754620-68844410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in many" "endothelial cell: 107.2;fibroblast: 115.9;pericyte: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubules: 79896222.2" "Tissue enhanced" "Detected in many" "intestine: 41555457.3" HPA008835 Supported Supported Mitochondria NA NA 19000 "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 7: Liver cancer - Metabolism" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 12 Mitochondria "HPA008835: " "unprognostic (2.08e-2)" "potential prognostic unfavorable (7.37e-5)" "unprognostic (2.26e-1)" "unprognostic (2.13e-1)" "unprognostic (2.76e-2)" "unprognostic (1.18e-1)" "unprognostic (3.20e-2)" "unprognostic (2.93e-1)" "unprognostic (1.07e-1)" "unprognostic (2.56e-1)" "validated prognostic favorable (6.86e-8)" "validated prognostic favorable (3.74e-4)" "unprognostic (6.29e-2)" "unprognostic (1.75e-1)" "unprognostic (9.40e-3)" "unprognostic (1.62e-1)" "unprognostic (2.11e-1)" "unprognostic (7.09e-2)" "unprognostic (3.83e-1)" "unprognostic (1.33e-3)" "unprognostic (9.86e-2)" "unprognostic (2.52e-2)" "unprognostic (2.91e-2)" "unprognostic (1.96e-1)" "unprognostic (1.74e-2)" "unprognostic (9.03e-2)" "unprognostic (4.41e-1)" "unprognostic (3.67e-1)" "unprognostic (3.02e-1)" "unprognostic (6.06e-2)" "unprognostic (2.89e-1)" CPT2 "CPT1, CPTASE" ENSG00000157184 "Carnitine palmitoyltransferase 2" P23786 1 53196792-53214197 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transport" "Acyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 85.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 107.9;Early primary spermatocytes: 71.2;Hepatocytes: 102.4;Retinal pigment epithelial cells: 63.9;Syncytiotrophoblasts: 68.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 102.4;Trophoblast cells: 107.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "liver: 82943304.1" "HPA028201, HPA028202, HPA028214" Enhanced Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 10 "Nucleoplasm, Mitochondria" Nucleoli "HPA028201: , HPA028202: , HPA028214: " "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "unprognostic (3.45e-2)" "unprognostic (1.34e-1)" "potential prognostic favorable (9.04e-6)" "unprognostic (1.58e-1)" "unprognostic (4.97e-1)" "unprognostic (7.57e-2)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (1.28e-4)" "potential prognostic favorable (8.96e-12)" "unprognostic (2.09e-3)" "unprognostic (1.66e-3)" "unprognostic (1.99e-1)" "unprognostic (1.85e-2)" "unprognostic (1.36e-1)" "unprognostic (9.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.33e-2)" "unprognostic (2.23e-1)" "unprognostic (9.06e-2)" "unprognostic (7.54e-2)" "unprognostic (1.71e-3)" "unprognostic (3.32e-1)" "unprognostic (8.32e-2)" "unprognostic (4.42e-2)" "unprognostic (8.84e-2)" "unprognostic (5.01e-3)" "unprognostic (2.24e-1)" "unprognostic (1.41e-1)" "unprognostic (6.41e-2)" CPTP "GLTPD1, MGC10334" ENSG00000224051 "Ceramide-1-phosphate transfer protein" Q5TA50 1 1324756-1328896 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 82.0;Early spermatids: 66.3;Enterocytes: 65.5;Esophageal apical cells: 272.7;Esophageal suprabasal cells: 67.2;Late primary spermatocytes: 137.3;Late spermatids: 286.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 272.7;Spermatogenic cell types: 286.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myofibers: 536497.4" "Tissue enhanced" "Detected in many" "cerebral cortex: 616799.3" HPA056832 Approved Supported "Cytosol,Perinuclear theca,Flagellar centriole,Mid piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Cytosol, Flagellar centriole, Mid piece" "Perinuclear theca" "HPA056832: " "unprognostic (2.40e-1)" "unprognostic (2.75e-1)" "unprognostic (9.82e-2)" "unprognostic (3.67e-2)" "unprognostic (6.54e-2)" "unprognostic (6.87e-2)" "unprognostic (1.45e-1)" "unprognostic (3.46e-3)" "unprognostic (7.69e-2)" "unprognostic (1.10e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (2.56e-5)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (2.32e-1)" "unprognostic (5.30e-2)" "unprognostic (9.54e-2)" "unprognostic (2.27e-2)" "unprognostic (2.06e-1)" "unprognostic (3.01e-2)" "unprognostic (1.33e-1)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (2.12e-1)" "unprognostic (1.42e-1)" "unprognostic (2.67e-2)" "unprognostic (5.18e-2)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" CRABP2 CRABP-II ENSG00000143320 "Cellular retinoic acid binding protein 2" P29373 1 156699606-156705816 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "cervix: 567.4;esophagus: 1174.0;vagina: 589.7" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 1358.3;Esophageal basal cells: 1650.7;Esophageal suprabasal cells: 4577.3" "Group enriched" "Detected in many" 4 "Apical squamous epithelial cells: 1358.3;Basal cells: 1650.7;Suprabasal cells: 4577.3" "Cell type enhanced" "Detected in many" "fibroblast: 19.1" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 1007.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "breast cancer: 849.1" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 47.7" "Group enriched" "Detected in many" "Fallopian tube cells: 6173864.8;Keratinocytes: 8349604.9" "Tissue enhanced" "Detected in all" "skin: 88023139.0" "HPA004135, CAB080413" Supported Supported Nucleoplasm,Cytosol NA NA 98000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 6 "Nucleoplasm, Cytosol" "CAB080413: , HPA004135: " "potential prognostic favorable (9.69e-5)" "unprognostic (3.81e-3)" "unprognostic (9.09e-2)" "unprognostic (2.06e-1)" "unprognostic (7.67e-2)" "unprognostic (1.89e-1)" "unprognostic (5.15e-2)" "unprognostic (3.46e-1)" "unprognostic (4.79e-2)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (3.54e-8)" "unprognostic (6.78e-2)" "unprognostic (6.31e-2)" "unprognostic (5.36e-3)" "unprognostic (7.54e-3)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (4.06e-5)" "unprognostic (4.69e-2)" "unprognostic (2.56e-1)" "unprognostic (1.54e-1)" "unprognostic (2.89e-2)" "unprognostic (5.09e-3)" "unprognostic (1.09e-2)" "unprognostic (3.97e-2)" "unprognostic (1.05e-2)" "unprognostic (7.94e-2)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (7.02e-4)" "unprognostic (1.55e-1)" "unprognostic (5.33e-3)" "unprognostic (1.64e-1)" CRACDL "C2orf55, KIAA1211L, MGC42367" ENSG00000196872 "CRACD like" Q6NV74 2 98793846-98936259 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0;epididymis: 29.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 164.4;Corticotrophs: 248.2;Epididymal principal cells: 448.6;Fallopian tube ciliated cells: 172.6;Respiratory ciliated cells: 298.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 298.4;Pituitary endocrine cells: 248.2;Reproductive supporting cells: 448.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 537.6" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 6 "amygdala: 71.5;basal ganglia: 90.8;cerebral cortex: 109.8;hippocampal formation: 107.6;white matter: 55.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Endothelial cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "amygdala: 23.2;basal ganglia: 54.1;cerebral cortex: 43.6;hippocampal formation: 64.4;olfactory bulb: 19.9" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 5820037.6;Fallopian tube cells: 1739351.4;Microglia and Neuropil: 4598658.8;Neurons: 4520299.4" "Tissue enriched" "Detected in some" "cerebral cortex: 25542303.9" "HPA051082, HPA061678" Enhanced Approved "Microtubules,Cytokinetic bridge,Centrosome" Yes No "Cluster 22: Epididymis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 "Microtubules, Centrosome" "Cytokinetic bridge" "HPA051082: , HPA061678: " "unprognostic (1.42e-2)" "unprognostic (3.41e-1)" "unprognostic (1.30e-2)" "unprognostic (5.29e-3)" "unprognostic (4.20e-1)" "unprognostic (2.63e-1)" "unprognostic (2.86e-1)" "unprognostic (7.89e-2)" "unprognostic (2.41e-2)" "potential prognostic favorable (2.77e-9)" "unprognostic (1.21e-2)" "unprognostic (1.77e-1)" "unprognostic (2.10e-1)" "unprognostic (2.25e-1)" "unprognostic (1.38e-1)" "unprognostic (9.15e-2)" "unprognostic (3.76e-2)" "unprognostic (2.43e-1)" "unprognostic (9.47e-2)" "unprognostic (1.44e-1)" "unprognostic (1.19e-1)" "unprognostic (7.33e-3)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (7.48e-2)" "unprognostic (7.48e-2)" "unprognostic (7.64e-3)" "unprognostic (2.14e-2)" CRAMP1 "CRAMP1L, KIAA1426" ENSG00000007545 "Cramped chromatin regulator homolog 1" Q96RY5 16 1612337-1677908 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 14.2;Somatotrophs: 16.3;Thyrotrophs: 15.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 77963.8;Neurons: 25640.1" "Not detected" "Not detected" HPA041752 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 Nucleoplasm "Nucleoli, Cytosol" "HPA041752: " "unprognostic (2.14e-2)" "unprognostic (3.42e-2)" "unprognostic (4.51e-3)" "unprognostic (2.30e-1)" "unprognostic (9.21e-2)" "unprognostic (5.59e-2)" "potential prognostic favorable (9.65e-4)" "unprognostic (1.72e-3)" "unprognostic (4.67e-1)" "unprognostic (2.36e-1)" "unprognostic (2.74e-3)" "unprognostic (1.80e-1)" "unprognostic (8.72e-3)" "unprognostic (4.25e-2)" "unprognostic (2.32e-2)" "unprognostic (3.73e-2)" "unprognostic (1.66e-2)" "unprognostic (2.66e-2)" "unprognostic (2.15e-1)" "unprognostic (2.97e-2)" "unprognostic (6.83e-3)" "unprognostic (1.20e-1)" "unprognostic (2.01e-3)" "unprognostic (2.69e-1)" "unprognostic (9.93e-2)" "unprognostic (1.34e-2)" "unprognostic (7.80e-2)" "unprognostic (4.01e-2)" "unprognostic (1.78e-2)" CREB3L4 "AIbZIP, ATCE1, CREB3, CREB4, hJAL" ENSG00000143578 "CAMP responsive element binding protein 3 like 4" Q8TEY5 1 153967534-153974361 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation, Unfolded protein response" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "prostate: 99.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 60.4;Gastric chief cells: 73.2;Goblet cells: 61.9;Mucous neck cells: 55.0;Prostatic glandular cells: 153.7" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 73.2;Glandular cells: 153.7" "Cell type enhanced" "Detected in many" "ependymal cell: 10.4" "Group enriched" "Detected in all" 4 "Breast Invasive Carcinoma (TCGA): 134.6;Prostate Adenocarcinoma (TCGA): 279.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 111.8" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 66 "Fallopian tube cells: 6593.0" "Not detected" "Not detected" HPA038122 Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 32: Basophils - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 2 "Nucleoplasm, Nuclear membrane" Mitochondria "HPA038122: " "unprognostic (9.18e-2)" "unprognostic (9.43e-2)" "unprognostic (2.11e-2)" "unprognostic (2.02e-1)" "unprognostic (8.38e-3)" "unprognostic (3.38e-2)" "unprognostic (2.34e-1)" "unprognostic (3.42e-3)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "unprognostic (2.33e-3)" "unprognostic (4.79e-3)" "unprognostic (1.44e-1)" "unprognostic (1.09e-2)" "unprognostic (8.33e-2)" "unprognostic (1.40e-1)" "unprognostic (2.97e-1)" "unprognostic (7.09e-2)" "unprognostic (9.58e-2)" "unprognostic (6.71e-2)" "unprognostic (1.50e-1)" "unprognostic (3.10e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (8.30e-2)" "unprognostic (1.52e-1)" "unprognostic (1.11e-1)" "unprognostic (7.54e-3)" "unprognostic (6.60e-2)" CREBBP "CBP, KAT3A, RSTS, RTS" ENSG00000005339 "CREB binding protein" Q92793 16 3725054-3880713 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1399.6" "Cell type enriched" "Detected in all" 4 "Neutrophils: 1399.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1528370.4" "Tissue enhanced" "Detected in many" "lymphoid tissue: 425279.6" "CAB004212, HPA055861" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 260 "Nucleoplasm, Nuclear bodies" "CAB004212: , HPA055861: " "unprognostic (3.44e-3)" "unprognostic (1.50e-1)" "unprognostic (2.44e-1)" "unprognostic (6.42e-2)" "unprognostic (2.35e-1)" "unprognostic (2.08e-2)" "unprognostic (2.99e-1)" "unprognostic (1.29e-1)" "unprognostic (7.44e-2)" "unprognostic (5.48e-2)" "validated prognostic favorable (1.90e-6)" "validated prognostic favorable (7.46e-4)" "unprognostic (2.43e-1)" "unprognostic (3.46e-3)" "unprognostic (3.97e-1)" "unprognostic (2.14e-1)" "unprognostic (6.45e-2)" "unprognostic (2.39e-1)" "unprognostic (4.87e-2)" "unprognostic (8.24e-2)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-3)" "unprognostic (1.49e-1)" "unprognostic (2.65e-2)" "unprognostic (3.10e-2)" "unprognostic (7.99e-2)" "unprognostic (7.88e-2)" "unprognostic (1.67e-1)" "unprognostic (7.22e-3)" "unprognostic (8.97e-2)" CREG1 CREG ENSG00000143162 "Cellular repressor of E1A stimulated genes 1" O75629 1 167529117-167553805 "Predicted secreted proteins" "Growth regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 306.0;Hofbauer cells: 1020.2;Kupffer cells: 1210.4" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 1210.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 55.9;classical monocyte: 128.5;eosinophil: 75.9;intermediate monocyte: 75.6;myeloid DC: 89.9;neutrophil: 43.8;non-classical monocyte: 72.7" "Group enriched" "Detected in all" 6 "dendritic cells: 89.9;granulocytes: 75.9;monocytes: 128.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Macrophages, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 4199161.1;Neutrophils: 4583251.2" "Low tissue specificity" "Detected in all" HPA056390 Approved "Golgi apparatus,Vesicles,Microtubules" "Secreted to blood" Other NA NA 680000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "Golgi apparatus, Vesicles" Microtubules "HPA056390: " "unprognostic (2.06e-1)" "unprognostic (1.15e-1)" "unprognostic (1.93e-1)" "unprognostic (1.79e-1)" "unprognostic (3.20e-1)" "unprognostic (1.48e-2)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (1.19e-2)" "unprognostic (2.87e-2)" "potential prognostic favorable (2.33e-5)" "unprognostic (1.01e-1)" "unprognostic (2.56e-3)" "unprognostic (7.63e-2)" "unprognostic (2.05e-3)" "unprognostic (2.15e-1)" "unprognostic (2.91e-1)" "unprognostic (1.26e-1)" "unprognostic (2.51e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (4.88e-4)" "unprognostic (8.87e-2)" "unprognostic (1.82e-2)" "unprognostic (5.14e-2)" "unprognostic (6.25e-2)" "unprognostic (4.32e-2)" "unprognostic (1.75e-2)" "unprognostic (1.52e-1)" "unprognostic (1.20e-1)" "unprognostic (5.51e-3)" "unprognostic (4.04e-1)" CRTC2 TORC2 ENSG00000160741 "CREB regulated transcription coactivator 2" Q53ET0 1 153947669-153958615 "Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 43.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 2037493.3;T-cells: 1943014.0" "Group enriched" "Detected in many" "bone marrow: 583263.2;lymphoid tissue: 2139345.5;ovary: 1053738.2" "HPA028454, HPA028465" Supported Enhanced Nucleoplasm NA NA 6800 "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 28 Nucleoplasm "HPA028454: , HPA028465: " "unprognostic (1.13e-2)" "unprognostic (4.78e-2)" "unprognostic (9.94e-2)" "unprognostic (4.34e-2)" "unprognostic (2.25e-2)" "unprognostic (4.92e-2)" "unprognostic (4.93e-1)" "unprognostic (1.08e-1)" "unprognostic (6.82e-2)" "unprognostic (1.12e-1)" "unprognostic (8.78e-2)" "unprognostic (3.42e-1)" "unprognostic (7.94e-3)" "unprognostic (5.66e-3)" "unprognostic (2.55e-1)" "unprognostic (7.55e-2)" "unprognostic (2.95e-2)" "unprognostic (1.43e-1)" "unprognostic (3.95e-1)" "unprognostic (7.40e-2)" "unprognostic (1.31e-1)" "unprognostic (1.62e-1)" "unprognostic (4.37e-3)" "unprognostic (1.68e-1)" "unprognostic (1.46e-2)" "unprognostic (4.01e-1)" "unprognostic (3.00e-1)" "unprognostic (8.44e-2)" "unprognostic (4.82e-2)" "unprognostic (1.41e-1)" "unprognostic (1.64e-2)" CRTC3 FLJ21868 ENSG00000140577 "CREB regulated transcription coactivator 3" Q6UUV7 15 90529923-90645345 "Cancer-related genes, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 3136617.8" "Group enriched" "Detected in some" 2489 "fallopian tube: 115466.7;intestine: 132918.5;lymphoid tissue: 338520.7;ovary: 408545.0" "HPA043735, HPA063691" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 9: T-cells - Adaptive immunity: Regulation" 24 Nucleoplasm Cytosol "HPA043735: , HPA063691: " "unprognostic (1.04e-2)" "unprognostic (2.68e-1)" "unprognostic (2.50e-1)" "unprognostic (2.79e-1)" "unprognostic (1.42e-1)" "unprognostic (7.41e-2)" "unprognostic (8.16e-2)" "unprognostic (4.47e-1)" "unprognostic (6.71e-2)" "unprognostic (5.04e-2)" "validated prognostic favorable (2.43e-6)" "validated prognostic favorable (5.75e-4)" "unprognostic (3.44e-1)" "unprognostic (8.01e-3)" "unprognostic (2.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" "unprognostic (4.98e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-2)" "unprognostic (2.58e-1)" "unprognostic (3.18e-1)" "unprognostic (1.40e-1)" "unprognostic (4.75e-1)" "unprognostic (1.87e-1)" "unprognostic (6.81e-2)" "unprognostic (4.57e-2)" "unprognostic (4.55e-2)" "unprognostic (8.08e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" CRX "CORD2, CRD, LCA7, OTX3" ENSG00000105392 "Cone-rod homeobox" O43186 19 47819779-47843330 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Sensory transduction, Transcription, Transcription regulation, Vision" "Activator, Developmental protein, DNA-binding" "Cone-rod dystrophy, Disease variant, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 122 "retina: 202.2" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 358.1;Retinal pigment epithelial cells: 370.9;Rod photoreceptor cells: 556.0" "Group enriched" "Detected in some" 38 "Neuronal cells: 556.0;Pigment cells: 370.9" "Group enriched" "Detected in some" 6 "choroid plexus epithelial cell: 3.6;upper rhombic lip: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.2;Uterine cancer: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036762, HPA036763" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Primary cilium,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 48: Non-specific - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 96 "Nucleoli fibrillar center" "Nucleoplasm, Primary cilium, Cytosol" "HPA036762: , HPA036763: " "unprognostic (5.61e-2)" CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 10537.6;skeletal muscle: 7429.7;tongue: 8772.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 1202.9;Endometrial glandular cells: 1087.8;Epididymal basal cells: 1094.8;Epididymal clear cells: 1281.9;Epididymal efferent duct absorptive cells: 3658.9;Epididymal efferent duct ciliated cells: 2186.2;Esophageal apical cells: 2670.2;Müller glia: 1134.1;Ocular epithelial cells: 1075.7;Pancreatic duct cells: 1898.2;Schwann cells: 3218.7;Thymic myoid cells: 3390.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 2670.2;Ciliated cells: 2186.2;Ductal cells: 3658.9;Glial cells: 3218.7;Stromal cells: 3390.9" "Cell type enhanced" "Detected in all" "astrocyte: 484.0;oligodendrocyte: 1086.7" "Group enriched" "Detected in all" 6 "Glioblastoma Multiforme (TCGA): 3128.0;Kidney Renal Clear Cell Carcinoma (TCGA): 2118.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 7571.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 236.2;ovarian cancer: 273.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Capillaries: 1667709101.6;Cardiomyocytes: 2843898306.2;Skeletal myofibers: 3848955664.0" "Group enriched" "Detected in all" "heart muscle: 3793822972.7;skeletal muscle: 3610862617.2" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" Other NA NA 510000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 74 "Plasma membrane, Cytosol" "CAB002053: , CAB040560: , HPA057100: " "unprognostic (9.83e-2)" "unprognostic (2.70e-2)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (5.21e-2)" "unprognostic (3.00e-2)" "unprognostic (9.22e-3)" "unprognostic (1.66e-3)" "unprognostic (3.72e-3)" "unprognostic (1.01e-3)" "unprognostic (1.22e-1)" "unprognostic (6.98e-3)" "unprognostic (3.96e-3)" "unprognostic (3.30e-1)" "unprognostic (1.45e-1)" "unprognostic (9.35e-2)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (9.18e-3)" "unprognostic (5.91e-2)" "unprognostic (5.27e-2)" "unprognostic (3.81e-1)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (9.71e-4)" "unprognostic (5.66e-2)" "unprognostic (2.25e-1)" "unprognostic (4.54e-2)" "unprognostic (1.61e-1)" "unprognostic (2.22e-1)" "unprognostic (1.15e-2)" CRYBB3 CRYB3 ENSG00000100053 "Crystallin beta B3" P26998 22 25199858-25207359 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Colonocytes: 2.3;Endometrial glandular cells: 2.4;Müller glia: 6.0;Prostatic club cells: 2.6;Respiratory basal cells: 2.6" "Cell type enhanced" "Detected in some" "Glial cells: 6.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 6146 "Glomeruli: 844488.1;Proximal tubules: 384673.4" "Tissue enriched" "Detected in single" 3104 "kidney: 310361.1" HPA055840 Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 37 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA055840: " "unprognostic (5.16e-3)" "unprognostic (4.14e-2)" "unprognostic (1.42e-1)" "unprognostic (2.83e-1)" "unprognostic (4.55e-2)" "unprognostic (3.08e-1)" "unprognostic (1.80e-2)" "unprognostic (1.35e-3)" "unprognostic (1.17e-2)" "unprognostic (1.76e-1)" CRYBG3 DKFZp667G2110 ENSG00000080200 "Crystallin beta-gamma domain containing 3" Q68DQ2 3 97822011-97944984 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 25.0" "Cell type enhanced" "Detected in many" "Renal collecting duct intercalated cells: 263.3;Retinal bipolar cells: 269.3" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "mammillary body: 311.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 8 "dendritic cells: 3.6;granulocytes: 1.5;monocytes: 1.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 188136.7;Pancreas epithelial cells: 281223.4" "Tissue enriched" "Detected in many" "pancreas: 8270894.2" HPA075635 Approved "Plasma membrane,Primary cilium" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "Plasma membrane" "Primary cilium" "HPA075635: " "unprognostic (8.91e-2)" "unprognostic (6.14e-2)" "unprognostic (1.08e-1)" "unprognostic (3.34e-3)" "unprognostic (1.09e-1)" "unprognostic (2.63e-2)" "unprognostic (8.73e-2)" "unprognostic (4.88e-2)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (8.80e-4)" "potential prognostic favorable (7.63e-5)" "unprognostic (1.01e-1)" "unprognostic (1.26e-1)" "unprognostic (8.15e-2)" "unprognostic (2.08e-3)" "unprognostic (4.85e-1)" "unprognostic (1.58e-1)" "unprognostic (5.69e-2)" "unprognostic (2.81e-2)" "unprognostic (1.46e-2)" "unprognostic (1.31e-1)" "unprognostic (1.82e-1)" "unprognostic (9.64e-2)" "unprognostic (7.47e-2)" "unprognostic (1.07e-1)" "unprognostic (4.92e-2)" "unprognostic (1.30e-1)" "unprognostic (2.04e-3)" "unprognostic (7.92e-2)" CRYZ ENSG00000116791 "Crystallin zeta" Q08257 1 74705482-74733408 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 308.8;liver: 264.3" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 117.6;Epididymal efferent duct ciliated cells: 131.4;Epididymal principal cells: 105.8;Hepatocytes: 261.1;Oocytes: 262.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 261.1;Oocytes: 262.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 77.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubules: 1348612536.8;Proximal tubules: 1082172808.3" "Low tissue specificity" "Detected in all" "HPA021921, HPA023290" Approved Supported Cytosol NA NA 3800000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 93: Hepatocytes - Bile production & excretion" 5 Cytosol "HPA021921: , HPA023290: " "unprognostic (2.50e-1)" "unprognostic (3.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (4.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.50e-2)" "unprognostic (1.31e-3)" "unprognostic (3.71e-2)" "unprognostic (1.60e-2)" "potential prognostic favorable (5.26e-11)" "unprognostic (4.41e-2)" "unprognostic (3.79e-2)" "unprognostic (2.04e-2)" "unprognostic (8.21e-2)" "unprognostic (1.63e-2)" "unprognostic (1.43e-1)" "unprognostic (1.54e-2)" "unprognostic (1.37e-1)" "unprognostic (1.89e-1)" "unprognostic (8.13e-2)" "unprognostic (3.57e-3)" "unprognostic (3.77e-1)" "unprognostic (2.23e-1)" "unprognostic (2.65e-2)" "unprognostic (2.55e-1)" "unprognostic (5.55e-2)" "unprognostic (1.57e-1)" "unprognostic (1.73e-1)" "unprognostic (9.00e-2)" "unprognostic (2.59e-1)" CSAD "CSD, PCAP" ENSG00000139631 "Cysteine sulfinic acid decarboxylase" Q9Y600 12 53157663-53180925 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 239.9" "Cell type enhanced" "Detected in many" "Adipocytes: 239.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 16.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 16.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 826454.9" "Tissue enhanced" "Detected in many" "skin: 412971.0" "HPA039487, HPA079296" Approved Approved "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA 5800 "Cluster 20: Non-specific - DNA binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 1 "Endoplasmic reticulum, Vesicles, Plasma membrane" "HPA039487: , HPA079296: " "unprognostic (9.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-3)" "unprognostic (2.57e-1)" "unprognostic (3.47e-2)" "unprognostic (7.35e-2)" "unprognostic (3.80e-3)" "unprognostic (2.80e-1)" "potential prognostic unfavorable (3.83e-5)" "unprognostic (1.22e-1)" "unprognostic (3.83e-2)" "validated prognostic favorable (1.09e-4)" "validated prognostic favorable (5.08e-4)" "unprognostic (8.00e-3)" "unprognostic (4.00e-1)" "unprognostic (4.22e-2)" "unprognostic (3.74e-2)" "unprognostic (1.92e-1)" "unprognostic (4.90e-3)" "potential prognostic favorable (2.46e-4)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (5.33e-2)" "unprognostic (5.74e-2)" "unprognostic (2.68e-2)" "unprognostic (4.32e-2)" "unprognostic (2.83e-2)" "unprognostic (1.88e-1)" "unprognostic (2.44e-1)" "unprognostic (6.17e-2)" CSE1L "CAS, CSE1, XPO2" ENSG00000124207 "Chromosome segregation 1 like" P55060 20 49046246-49096960 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 198.0;Erythrocyte progenitors: 182.6;Late primary spermatocytes: 199.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 375681675.4" "Low tissue specificity" "Detected in all" "CAB002140, HPA038059, HPA038060" Enhanced Enhanced Nucleoplasm,Cytosol No Yes 530000 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 61 Nucleoplasm Cytosol "CAB002140: , HPA038059: , HPA038060: " "unprognostic (1.22e-2)" "unprognostic (1.88e-3)" "unprognostic (2.67e-1)" "unprognostic (1.19e-3)" "unprognostic (1.80e-1)" "unprognostic (8.35e-2)" "unprognostic (3.43e-1)" "unprognostic (1.22e-1)" "unprognostic (7.05e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (4.41e-5)" "unprognostic (2.70e-1)" "unprognostic (7.83e-3)" "validated prognostic unfavorable (2.93e-6)" "validated prognostic unfavorable (4.19e-4)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (2.45e-3)" "unprognostic (1.23e-1)" "unprognostic (1.55e-1)" "unprognostic (1.63e-1)" "unprognostic (2.92e-3)" "potential prognostic unfavorable (8.84e-4)" "unprognostic (1.14e-2)" "unprognostic (3.12e-2)" "potential prognostic favorable (8.00e-4)" "unprognostic (1.31e-2)" "unprognostic (1.70e-1)" "unprognostic (2.71e-1)" "unprognostic (2.66e-1)" "unprognostic (1.27e-1)" "unprognostic (9.42e-2)" CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 101.5;Fibroblasts: 73.2;Mast cells: 343.1;Megakaryocyte progenitors: 125.9;Megakaryocyte-Erythroid progenitors: 451.5;Pancreatic duct cells: 107.7;Schwann cells: 75.3" "Cell type enhanced" "Detected in many" "Mast cells: 343.1;Megakaryocytes: 451.5" "Cell type enhanced" "Detected in many" "fibroblast: 159.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" "kidney: 163342.1;lymphoid tissue: 181478.6;ovary: 48328.1;salivary gland: 97422.2" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" Cytokine NA NA 270000 8800000 "Cluster 19: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 58: Mast cells - Allergic inflammatory responses" 7 "Plasma membrane" "Nuclear bodies" "HPA076624: " "unprognostic (1.23e-1)" "unprognostic (8.11e-3)" "unprognostic (1.84e-1)" "unprognostic (7.29e-2)" "unprognostic (6.91e-2)" "unprognostic (5.69e-2)" "unprognostic (3.33e-1)" "unprognostic (3.65e-3)" "unprognostic (5.63e-2)" "unprognostic (1.70e-1)" "unprognostic (2.94e-3)" "unprognostic (1.33e-1)" "unprognostic (8.42e-2)" "potential prognostic unfavorable (2.14e-5)" "unprognostic (1.09e-1)" "unprognostic (1.45e-1)" "unprognostic (6.52e-3)" "unprognostic (1.59e-1)" "unprognostic (1.09e-1)" "unprognostic (4.91e-2)" "unprognostic (4.26e-1)" "unprognostic (3.59e-1)" "unprognostic (1.83e-2)" "unprognostic (7.50e-2)" "unprognostic (9.71e-2)" "unprognostic (5.82e-3)" "unprognostic (8.95e-3)" "unprognostic (8.24e-2)" "unprognostic (3.04e-2)" "unprognostic (2.72e-1)" "unprognostic (4.02e-2)" CSF2 "GM-CSF, GMCSF" ENSG00000164400 "Colony stimulating factor 2" P04141 5 132073789-132076170 "Cancer-related genes, Predicted secreted proteins" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lung: 1.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 15.2;Endometrial secretory cells: 3.6;Innate lymphoid cells: 59.2;Mast cells: 13.9;NK-cells: 8.1;T-cells: 18.4" "Cell type enhanced" "Detected in some" "Alveolar cells: 15.2;Innate lymphoid cells: 59.2;Mast cells: 13.9;T-cells: 18.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 8.0" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "NK-cell: 6.3" "Lineage enriched" "Detected in single" 12 "NK-cells: 6.3" "Cancer enhanced" "Detected in many" "Bile duct cancer: 27.2;Kidney cancer: 31.4" "Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057404, HPA062006" Enhanced Vesicles "Secreted to blood" Cytokine NA NA 23900 "Cluster 15: NK-cells - Unknown function" "Cluster 13: Lung - Secretion" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 4 Vesicles "HPA057404: , HPA062006: " "unprognostic (1.05e-3)" "unprognostic (5.93e-2)" "unprognostic (2.47e-1)" "unprognostic (4.29e-1)" "unprognostic (2.06e-3)" "potential prognostic favorable (8.91e-4)" "unprognostic (2.40e-1)" "unprognostic (4.07e-3)" "unprognostic (5.74e-3)" "unprognostic (4.25e-3)" "unprognostic (5.69e-2)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (2.39e-2)" "unprognostic (6.94e-2)" CSK ENSG00000103653 "C-terminal Src kinase" P41240 15 74782080-74803197 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 158.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 201.3;Megakaryocytes: 98.9;monocytes: 122.9;Neutrophils: 178.1;Tuft cells: 149.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 201.3;Neutrophils: 178.1" "Cell type enhanced" "Detected in all" "leukocyte: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "B-cells: 89816484.2;Macrophages: 45674641.5;T-cells: 68115082.9" "Tissue enriched" "Detected in all" "lymphoid tissue: 87284336.6" "CAB011203, HPA026488, HPA028425" Approved Approved Enhanced Vesicles,Cytosol No No 580000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 49 "Vesicles, Cytosol" "CAB011203: , HPA026488: , HPA028425: " "unprognostic (3.08e-1)" "unprognostic (9.45e-2)" "unprognostic (2.61e-1)" "unprognostic (1.15e-2)" "unprognostic (8.09e-2)" "unprognostic (7.31e-2)" "unprognostic (1.59e-1)" "unprognostic (2.56e-2)" "unprognostic (3.07e-2)" "unprognostic (3.12e-1)" "unprognostic (2.54e-2)" "unprognostic (2.47e-1)" "unprognostic (3.46e-1)" "unprognostic (1.75e-2)" "unprognostic (5.72e-2)" "unprognostic (1.36e-1)" "unprognostic (2.30e-2)" "unprognostic (2.55e-1)" "unprognostic (2.97e-1)" "unprognostic (7.22e-2)" "unprognostic (5.59e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (1.73e-1)" "unprognostic (2.99e-1)" "unprognostic (3.14e-1)" "unprognostic (1.79e-3)" "unprognostic (2.78e-2)" "unprognostic (8.67e-2)" "potential prognostic favorable (5.88e-4)" CSNK1A1 "CK1, CK1a, CK1alpha, CKIa, CKIalpha" ENSG00000113712 "Casein kinase 1 alpha 1" P48729 5 149492982-149551471 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Keratinocytes: 60317133.6" "Low tissue specificity" "Detected in many" "CAB016680, HPA051334" Uncertain Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 127 Cytosol "CAB016680: , HPA051334: " "unprognostic (1.04e-1)" "potential prognostic unfavorable (8.62e-4)" "unprognostic (8.89e-2)" "unprognostic (7.90e-2)" "unprognostic (1.50e-2)" "unprognostic (1.66e-1)" "unprognostic (4.00e-2)" "unprognostic (3.07e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (3.07e-4)" "potential prognostic favorable (5.21e-4)" "unprognostic (5.40e-2)" "unprognostic (2.11e-2)" "unprognostic (4.42e-3)" "unprognostic (3.72e-2)" "unprognostic (1.90e-2)" "unprognostic (1.62e-1)" "unprognostic (2.32e-2)" "unprognostic (1.23e-1)" "unprognostic (2.14e-2)" "unprognostic (3.76e-3)" "potential prognostic unfavorable (6.44e-6)" "unprognostic (3.41e-3)" "unprognostic (7.68e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (1.64e-1)" "unprognostic (3.06e-1)" "unprognostic (1.36e-1)" "unprognostic (7.52e-3)" "unprognostic (4.09e-1)" CSNK1A1L MGC33182 ENSG00000180138 "Casein kinase 1 alpha 1 like" Q8N752 13 37103259-37105664 "Enzymes, Predicted intracellular proteins" "Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.3" "Group enriched" "Detected in some" 17 "Early primary spermatocytes: 8.3;Early spermatids: 26.1;Late primary spermatocytes: 27.1;Late spermatids: 30.0" "Cell type enriched" "Detected in some" 23 "Spermatogenic cell types: 30.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 33 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 39 "granulocytes: 7.6" "Not detected" "Not detected" "Lung - Neutrophils_2, Spleen - Neutrophils_2" "Not detected" "Not detected" "Not detected" "Not detected" HPA051334 Approved Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 3: Early primary spermatocytes - Early meiosis" 7 Cytosol "HPA051334: " CSNK1D "CKID, CKIdelta, HCKID" ENSG00000141551 "Casein kinase 1 delta" P48730 17 82239023-82273700 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 371.3;Late spermatids: 1358.7;Neutrophils: 605.0" "Group enriched" "Detected in all" 4 "Neutrophils: 605.0;Spermatogenic cell types: 1358.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 6965929.6" "Tissue enhanced" "Detected in many" "ovary: 5385547.9" "CAB015410, HPA070888, HPA072593" Approved Supported "Plasma membrane,Actin filaments,Primary cilium,Cytosol,Principal piece,End piece" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 80 "Plasma membrane, Cytosol" "Actin filaments, Primary cilium, Principal piece, End piece" "CAB015410: , HPA070888: , HPA072593: " "unprognostic (1.36e-1)" "unprognostic (6.98e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (2.18e-2)" "unprognostic (6.54e-2)" "unprognostic (5.32e-2)" "unprognostic (7.78e-2)" "unprognostic (1.92e-2)" "unprognostic (1.13e-3)" "unprognostic (2.39e-2)" "unprognostic (7.58e-2)" "unprognostic (6.12e-2)" "validated prognostic unfavorable (1.10e-5)" "validated prognostic unfavorable (5.43e-4)" "unprognostic (1.11e-1)" "unprognostic (8.86e-2)" "unprognostic (6.25e-3)" "unprognostic (1.92e-2)" "unprognostic (1.60e-1)" "unprognostic (2.54e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (1.17e-2)" "unprognostic (3.63e-2)" "unprognostic (2.96e-1)" "unprognostic (2.54e-1)" "unprognostic (1.16e-1)" "unprognostic (2.45e-1)" "unprognostic (3.37e-2)" "unprognostic (2.27e-1)" CSNK1E "CKIE, CKIepsilon, HCKIE" ENSG00000213923 "Casein kinase 1 epsilon" P49674 22 38290691-38318084 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 117.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 2151911.8" "Tissue enhanced" "Detected in many" "cerebral cortex: 1347449.8;ovary: 928728.9" "CAB009626, HPA026288" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 22: Non-specific - Basic cellular functions" 108 "Nucleoplasm, Cytosol" "CAB009626: , HPA026288: " "unprognostic (7.95e-2)" "unprognostic (1.73e-1)" "unprognostic (1.86e-1)" "unprognostic (2.51e-3)" "unprognostic (4.05e-1)" "unprognostic (2.31e-1)" "unprognostic (1.19e-2)" "unprognostic (2.90e-3)" "unprognostic (3.64e-2)" "unprognostic (2.07e-1)" "unprognostic (9.27e-3)" "unprognostic (1.96e-2)" "unprognostic (4.95e-2)" "potential prognostic unfavorable (1.42e-7)" "unprognostic (7.18e-2)" "unprognostic (2.26e-3)" "unprognostic (4.66e-3)" "unprognostic (1.18e-1)" "unprognostic (1.56e-3)" "unprognostic (8.45e-2)" "unprognostic (2.56e-1)" "unprognostic (7.61e-2)" "unprognostic (3.01e-3)" "unprognostic (3.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.60e-2)" "unprognostic (2.24e-1)" "unprognostic (2.22e-1)" "unprognostic (4.82e-2)" "unprognostic (2.38e-2)" "unprognostic (5.18e-2)" CSNK2A1 "Cka1, Cka2" ENSG00000101266 "Casein kinase 2 alpha 1" P68400 20 472498-543835 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 100251286.5" "Tissue enhanced" "Detected in all" "cerebral cortex: 54359514.1" "CAB020680, HPA059206, HPA061698, CAB069395" Supported Supported "Nucleoplasm,Primary cilium" NA NA 510000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 621 Nucleoplasm "Primary cilium" "CAB020680: , CAB069395: , HPA059206: , HPA061698: " "unprognostic (3.45e-1)" "unprognostic (3.30e-2)" "unprognostic (2.18e-1)" "unprognostic (5.53e-2)" "unprognostic (6.59e-2)" "unprognostic (6.17e-2)" "unprognostic (1.91e-1)" "unprognostic (1.59e-2)" "unprognostic (5.51e-2)" "unprognostic (3.86e-2)" "unprognostic (2.22e-3)" "unprognostic (5.17e-2)" "unprognostic (2.37e-1)" "validated prognostic unfavorable (7.59e-6)" "validated prognostic unfavorable (8.14e-5)" "unprognostic (1.72e-2)" "unprognostic (7.02e-2)" "unprognostic (3.48e-2)" "unprognostic (2.68e-1)" "unprognostic (3.28e-1)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (6.69e-4)" "unprognostic (9.30e-3)" "unprognostic (1.33e-1)" "unprognostic (2.16e-2)" "unprognostic (2.15e-1)" "unprognostic (5.01e-1)" "unprognostic (1.83e-1)" "unprognostic (7.46e-2)" "unprognostic (2.10e-2)" "unprognostic (1.48e-1)" CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 124.5" "Cell type enhanced" "Detected in some" "Adipocytes: 52.3;Epicardial cells: 38.7;Melanocytes: 39.2;Oligodendrocyte progenitor cells: 101.9;Pericytes: 68.1;Salivary myoepithelial cells: 22.0;Schwann cells: 54.1;Smooth muscle cells: 63.8;Thymic myoid cells: 78.9;Vascular smooth muscle cells: 129.4" "Cell type enhanced" "Detected in many" "Adipocytes: 52.3;Glial cells: 101.9;Mural cells: 129.4;Smooth muscle cells: 63.8;Stromal cells: 78.9" "Group enriched" "Detected in some" 5 "oligodendrocyte precursor cell: 111.5;pericyte: 105.3;vascular associated smooth muscle cell: 115.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 124.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 73.0" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Testis - Endothelial cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 156171457.6" "Group enriched" "Detected in many" "blood vessel: 468315224.9;intestine: 163347533.0" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Approved "Plasma membrane" NA NA 29000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 30 "Plasma membrane" "CAB016189: , HPA001933: , HPA002951: , HPA042785: , HPA050008: " "unprognostic (2.60e-1)" "unprognostic (7.39e-3)" "unprognostic (2.96e-1)" "unprognostic (1.99e-2)" "unprognostic (2.15e-1)" "unprognostic (6.36e-2)" "unprognostic (6.93e-2)" "unprognostic (1.03e-1)" "unprognostic (3.89e-1)" "unprognostic (4.21e-2)" "validated prognostic favorable (2.38e-4)" "validated prognostic favorable (4.69e-4)" "potential prognostic unfavorable (9.29e-5)" "unprognostic (1.70e-2)" "unprognostic (2.34e-1)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (9.38e-4)" "unprognostic (4.91e-2)" "unprognostic (1.55e-1)" "unprognostic (1.55e-2)" "unprognostic (2.77e-1)" "unprognostic (4.05e-2)" "unprognostic (8.16e-2)" "unprognostic (2.02e-1)" "unprognostic (1.93e-2)" "unprognostic (1.92e-2)" "unprognostic (1.78e-1)" "unprognostic (2.59e-2)" "unprognostic (1.07e-2)" "unprognostic (2.03e-2)" "unprognostic (7.84e-2)" CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 21 "skin 1: 1026.8" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 1345.6" "Cell type enriched" "Detected in many" 4 "Apical squamous epithelial cells: 1345.6" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 1.6;upper rhombic lip: 1.3" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 125.2;Thyroid Carcinoma (TCGA): 419.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 203.3;Bladder cancer: 187.9;pancreatic cancer: 182.1" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Keratinocytes: 3932742.2;T-cells: 991081.4" "Group enriched" "Detected in all" "intestine: 79188014.2;skin: 273319592.0" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" "Enzyme inhibitor" NA NA 18000000 "Cluster 9: Skin - Hair follicle development" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 22 "Plasma membrane" Cytosol "CAB019316: , HPA044963: " "unprognostic (5.87e-2)" "unprognostic (1.49e-2)" "unprognostic (1.04e-1)" "unprognostic (7.54e-2)" "unprognostic (6.04e-2)" "unprognostic (2.50e-1)" "unprognostic (7.91e-2)" "unprognostic (1.19e-1)" "unprognostic (8.62e-3)" "unprognostic (7.85e-3)" "unprognostic (1.76e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-2)" "unprognostic (3.46e-2)" "unprognostic (3.68e-3)" "unprognostic (1.89e-2)" "unprognostic (3.29e-1)" "unprognostic (2.33e-3)" "unprognostic (6.28e-3)" "unprognostic (2.38e-1)" "unprognostic (2.93e-2)" "unprognostic (4.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.25e-2)" "unprognostic (1.09e-1)" "unprognostic (2.44e-2)" "unprognostic (1.43e-2)" CSTA "STF1, STFA" ENSG00000121552 "Cystatin A" P01040 3 122325248-122341969 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 1354.2;esophagus: 5787.1;vagina: 1836.0" "Group enriched" "Detected in many" 16 "Esophageal apical cells: 161499.9;Esophageal suprabasal cells: 49103.0" "Group enriched" "Detected in many" 30 "Apical squamous epithelial cells: 161499.9;Suprabasal cells: 49103.0" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 1.0;leukocyte: 2.7" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 834.3;Head and Neck Squamous Cell Carcinoma (TCGA): 1280.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 19 "classical monocyte: 516.2;intermediate monocyte: 269.6;myeloid DC: 383.7;neutrophil: 246.8;non-classical monocyte: 162.5" "Group enriched" "Detected in all" 193 "dendritic cells: 383.7;granulocytes: 246.8;monocytes: 516.2" "Cancer enhanced" "Detected in many" "cervical cancer: 157.7;head and neck cancer: 297.3" "Adipose subcutaneous - Adipocytes (Subcutaneous), Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Thyroid gland - Macrophages" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in all" "Keratinocytes: 193579142.9" "Tissue enhanced" "Detected in all" "intestine: 12706682949.0" "CAB000469, HPA001031, CAB047315" Enhanced Approved Nucleoplasm,Cytosol No No 12000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 24 "Nucleoplasm, Cytosol" "CAB000469: , CAB047315: , HPA001031: " "unprognostic (4.12e-1)" "unprognostic (4.38e-3)" "unprognostic (2.48e-1)" "unprognostic (9.20e-2)" "unprognostic (2.34e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (4.90e-2)" "potential prognostic favorable (7.58e-4)" "unprognostic (8.10e-2)" "unprognostic (2.11e-3)" "unprognostic (1.45e-1)" "unprognostic (1.14e-1)" "unprognostic (2.72e-1)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (9.14e-2)" "unprognostic (2.16e-3)" "unprognostic (1.13e-1)" "unprognostic (1.54e-1)" "unprognostic (1.34e-2)" "unprognostic (6.01e-2)" "unprognostic (1.34e-2)" "unprognostic (1.79e-1)" "unprognostic (1.81e-1)" "unprognostic (7.69e-2)" "unprognostic (9.08e-2)" "unprognostic (4.83e-2)" "unprognostic (4.53e-2)" "unprognostic (1.06e-2)" "unprognostic (4.67e-2)" CSTF2T "CstF-64T, DKFZp434C1013, KIAA0689, tauCstF-64" ENSG00000177613 "Cleavage stimulation factor subunit 2 tau variant" Q9H0L4 10 51695486-51699595 "Predicted intracellular proteins" "mRNA processing" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lung: 3838595.9" "HPA039216, HPA062021" Approved Approved "Nucleoplasm,Vesicles,Basal body" No No "Cluster 1: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 30 Nucleoplasm "Vesicles, Basal body" "HPA039216: , HPA062021: " "unprognostic (9.11e-3)" "unprognostic (2.35e-2)" "unprognostic (5.22e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-1)" "unprognostic (9.52e-2)" "unprognostic (5.05e-2)" "potential prognostic favorable (2.25e-5)" "unprognostic (2.11e-1)" "unprognostic (2.83e-2)" "potential prognostic favorable (4.99e-5)" "unprognostic (1.08e-2)" "unprognostic (7.70e-2)" "unprognostic (1.97e-3)" "unprognostic (5.26e-2)" "unprognostic (8.45e-2)" "unprognostic (1.57e-1)" "unprognostic (1.20e-1)" "unprognostic (4.30e-3)" "unprognostic (4.33e-1)" "unprognostic (1.75e-1)" "unprognostic (4.00e-2)" "unprognostic (5.88e-2)" "unprognostic (9.07e-2)" "unprognostic (2.49e-2)" "unprognostic (1.25e-1)" "unprognostic (3.64e-1)" "unprognostic (9.99e-2)" "unprognostic (3.31e-1)" "unprognostic (6.31e-2)" "unprognostic (3.15e-1)" CT45A1 "CT45-1, CT45.1" ENSG00000268940 "Cancer/testis antigen family 45 member A1" Q5HYN5 X 135713639-135723539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 12.9" "Group enriched" "Detected in some" 9 "Differentiating spermatogonia: 6.6;Early primary spermatocytes: 7.5" "Cell type enriched" "Detected in single" 10 "Spermatogenic cell types: 7.5" "Cell type enriched" "Detected in single" 10 "endothelial cell: 9.2" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 17.4;Ovary Serous Cystadenocarcinoma (TCGA): 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 48.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 67: Testis - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 18 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (1.68e-2)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (2.69e-1)" "unprognostic (1.43e-2)" "unprognostic (1.58e-1)" "unprognostic (4.72e-1)" "unprognostic (5.54e-1)" CT45A10 ENSG00000269586 "Cancer/testis antigen family 45 member A10" P0DMU9 X 135881063-135893444 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 8.7" "Group enriched" "Detected in some" 7 "Differentiating spermatogonia: 62.0;Early primary spermatocytes: 33.4" "Cell type enriched" "Detected in some" 55 "Spermatogenic cell types: 62.0" "Cell type enriched" "Detected in single" 21 "endothelial cell: 2.1" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 10.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 67: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 4 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (2.52e-2)" "unprognostic (1.65e-2)" "unprognostic (4.50e-1)" "unprognostic (1.19e-1)" "unprognostic (2.09e-2)" "unprognostic (5.42e-3)" "unprognostic (7.17e-1)" "unprognostic (6.45e-1)" "unprognostic (6.89e-2)" "unprognostic (4.68e-1)" "unprognostic (1.46e-3)" CT45A2 "CT45-2, CT45.2" ENSG00000271449 "Cancer/testis antigen family 45 member A2" Q5DJT8 X 135811668-135820012 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 55: Lymphoma - Immune response" 1 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " CT45A3 "CT45-3, CT45-4, CT45.3, CT45.4, CT45A4" ENSG00000269096 "Cancer/testis antigen family 45 member A3" Q8NHU0 X 135759846-135768191 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 6.1" "Cell type enhanced" "Detected in single" "Differentiating spermatogonia: 1.1" "Cell type enriched" "Detected in single" 11 "Spermatogenic cell types: 1.1" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 10.6;Ovary Serous Cystadenocarcinoma (TCGA): 8.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 19.0;Myeloma: 17.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 67: Testis - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 3 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (1.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-1)" "unprognostic (6.19e-1)" "unprognostic (1.83e-2)" "unprognostic (3.65e-1)" "unprognostic (5.30e-1)" "unprognostic (2.00e-2)" CT45A5 "CT45-5, CT45.5" ENSG00000228836 "Cancer/testis antigen family 45 member A5" P0DMU8 X 135775852-135785503 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.3;testis: 4.8" "Cell type enhanced" "Detected in single" "Differentiating spermatogonia: 1.1" "Cell type enriched" "Detected in single" 11 "Spermatogenic cell types: 1.1" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 22.7;Myeloma: 29.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 5 "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (3.04e-1)" "unprognostic (7.53e-1)" "unprognostic (3.34e-2)" "potential prognostic unfavorable (5.42e-5)" "unprognostic (1.62e-1)" "unprognostic (6.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.89e-2)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (9.98e-2)" CT45A6 "CT45-6, CT45.6" ENSG00000278289 "Cancer/testis antigen family 45 member A6" P0DMU7 X 135794685-135802787 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 3.5;pituitary gland: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 55: Lymphoma - Immune response" "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (1.93e-1)" CT45A7 ENSG00000273696 "Cancer/testis antigen family 45 member A7" P0DMV0 X 135829229-135837280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 1.5;Ovary Serous Cystadenocarcinoma (TCGA): 1.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 51: Myeloma - Immunoglobulins" "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (2.53e-1)" CT45A8 ENSG00000278085 "Cancer/testis antigen family 45 member A8" P0DMV1 X 135846497-135854538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "lymphoma: 9.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 55: Lymphoma - Immune response" "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " CT45A9 ENSG00000270946 "Cancer/testis antigen family 45 member A9" P0DMV2 X 135863418-135871812 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 2.2;Ovary Serous Cystadenocarcinoma (TCGA): 2.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.4;Sarcoma: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044735, HPA044757, HPA046872, HPA046987" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 49: HMC-1 - Innate immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" "Nucleoplasm, Nucleoli" "HPA044735: , HPA044757: , HPA046872: , HPA046987: " "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (4.08e-2)" "unprognostic (8.77e-2)" CTAG1A "ESO1, LAGE2A" ENSG00000268651 "Cancer/testis antigen 1A" P78358 X 154585133-154586816 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "testis: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 12.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 145.3" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013061, HPA063039" Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 58 "Golgi apparatus, Vesicles" "CAB013061: , HPA063039: " "unprognostic (1.30e-1)" "unprognostic (3.02e-1)" "unprognostic (2.31e-3)" "unprognostic (7.39e-1)" "unprognostic (3.82e-1)" "unprognostic (1.13e-1)" "unprognostic (3.19e-1)" "unprognostic (5.24e-1)" "unprognostic (1.07e-1)" CTAG1B "CT6.1, CTAG, CTAG1, ESO1, LAGE2A, LAGE2B, NY-ESO-1" ENSG00000184033 "Cancer/testis antigen 1B" P78358 X 154617609-154619282 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 25 "testis: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Myeloma: 64.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB015453, HPA063039" Enhanced Uncertain "Golgi apparatus,Vesicles" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" 60 "Golgi apparatus, Vesicles" "CAB015453: , HPA063039: " "unprognostic (8.80e-3)" "unprognostic (2.60e-2)" "unprognostic (3.28e-2)" "unprognostic (2.94e-1)" "unprognostic (3.66e-1)" "unprognostic (1.59e-1)" "unprognostic (2.52e-1)" "unprognostic (7.08e-2)" "unprognostic (3.04e-1)" "unprognostic (2.99e-1)" "unprognostic (5.45e-2)" "unprognostic (7.43e-1)" CTDNEP1 "DULLARD, HSA011916, NET56" ENSG00000175826 "CTD nuclear envelope phosphatase 1" O95476 17 7243591-7252491 "Enzymes, Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 395.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 22.1;Brain excitatory neurons: 19.0;Brain inhibitory neurons: 18.7;Ependymal cells: 22.2;Microglia: 20.1;Oligodendrocyte progenitor cells: 20.5;Oligodendrocytes: 27.2;Other brain neurons: 19.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 22.2;Glial cells: 27.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1825026.9" "Tissue enhanced" "Detected in some" "cerebral cortex: 268156.3;lymphoid tissue: 158224.6" "HPA037439, HPA066466" Uncertain Approved "Lipid droplets" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "Lipid droplets" "HPA037439: , HPA066466: " "unprognostic (9.60e-3)" "unprognostic (2.65e-1)" "unprognostic (2.53e-2)" "unprognostic (1.07e-1)" "unprognostic (1.41e-1)" "unprognostic (1.06e-1)" "unprognostic (1.82e-1)" "unprognostic (1.06e-1)" "unprognostic (1.65e-1)" "unprognostic (4.79e-3)" "unprognostic (3.78e-3)" "unprognostic (3.18e-1)" "unprognostic (5.20e-3)" "unprognostic (3.75e-2)" "unprognostic (1.00e-2)" "unprognostic (1.64e-1)" "unprognostic (8.48e-2)" "unprognostic (2.68e-1)" "unprognostic (9.66e-2)" "unprognostic (7.89e-2)" "unprognostic (1.89e-2)" "unprognostic (1.59e-2)" "unprognostic (8.16e-2)" "unprognostic (3.76e-1)" "unprognostic (2.41e-1)" "unprognostic (5.61e-2)" "unprognostic (1.36e-1)" "unprognostic (9.39e-2)" "unprognostic (1.82e-2)" "unprognostic (2.37e-2)" CTDSPL2 "FLJ10523, HSPC129" ENSG00000137770 "CTD small phosphatase like 2" Q05D32 15 44427622-44529038 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 3129104.5;T-cells: 3715562.1" "Group enriched" "Detected in many" "bone marrow: 666064.1;intestine: 747459.3;lymphoid tissue: 217338.1;ovary: 392645.5" "HPA040763, HPA062198" Approved Approved Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 22 Nucleoplasm "HPA040763: , HPA062198: " "unprognostic (1.30e-1)" "unprognostic (1.61e-1)" "unprognostic (4.87e-2)" "unprognostic (3.93e-1)" "unprognostic (1.64e-1)" "unprognostic (1.46e-2)" "unprognostic (1.98e-2)" "unprognostic (1.96e-2)" "unprognostic (1.74e-1)" "potential prognostic unfavorable (9.46e-4)" "potential prognostic favorable (9.68e-5)" "unprognostic (9.74e-3)" "unprognostic (4.31e-1)" "unprognostic (3.77e-2)" "unprognostic (4.04e-2)" "unprognostic (8.43e-2)" "unprognostic (2.23e-2)" "unprognostic (3.71e-1)" "unprognostic (2.67e-2)" "unprognostic (2.85e-2)" "unprognostic (1.96e-2)" "unprognostic (1.13e-3)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (5.72e-2)" "unprognostic (1.19e-2)" "unprognostic (8.50e-2)" "unprognostic (2.77e-2)" "unprognostic (8.05e-2)" "unprognostic (3.19e-1)" "unprognostic (4.41e-3)" "unprognostic (1.36e-1)" CTNNBL1 "C20orf33, FLJ21108, NAP, NYD-SP19, P14, P14L" ENSG00000132792 "Catenin beta like 1" Q8WYA6 20 37693955-37872129 "Cancer-related genes, Disease related genes, Essential proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, mRNA processing, mRNA splicing" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 410.9;Late primary spermatocytes: 279.0;Mast cells: 513.8;Megakaryocyte-Erythroid progenitors: 461.3" "Cell type enhanced" "Detected in all" "Mast cells: 513.8;Megakaryocytes: 461.3;Spermatogenic cell types: 410.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA004742, HPA027906, HPA027907" Approved Supported Nucleoplasm,Centrosome,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 58: Mast cells - Allergic inflammatory responses" 60 Nucleoplasm "Centrosome, Cytosol" "HPA004742: , HPA027906: , HPA027907: " "unprognostic (1.20e-1)" "unprognostic (4.18e-2)" "unprognostic (1.13e-1)" "unprognostic (1.09e-1)" "unprognostic (1.16e-1)" "unprognostic (1.30e-2)" "unprognostic (3.50e-1)" "unprognostic (1.76e-3)" "unprognostic (3.41e-2)" "unprognostic (4.27e-3)" "potential prognostic favorable (4.07e-4)" "unprognostic (5.73e-3)" "unprognostic (2.20e-1)" "unprognostic (2.00e-3)" "unprognostic (6.22e-2)" "unprognostic (3.03e-2)" "unprognostic (1.77e-2)" "unprognostic (2.34e-2)" "unprognostic (3.64e-1)" "unprognostic (1.23e-2)" "unprognostic (2.86e-2)" "unprognostic (4.42e-3)" "unprognostic (4.07e-2)" "unprognostic (1.22e-2)" "unprognostic (1.95e-1)" "unprognostic (1.15e-3)" "unprognostic (2.95e-1)" "unprognostic (3.32e-1)" "unprognostic (1.36e-1)" "unprognostic (4.55e-1)" "unprognostic (3.76e-1)" CTPS1 "CTPS, GATD5A" ENSG00000171793 "CTP synthase 1" P17812 1 40979300-41012565 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 92.3;Salivary acinar cells: 80.4;Smooth muscle cells: 94.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 7 "Adrenocortical cancer: 588.4" "Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 27103849.0" "Tissue enhanced" "Detected in many" "salivary gland: 25994897.4" "CAB017111, HPA051322" Enhanced Approved "Actin filaments,Cytosol" NA Yes 100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 24 Cytosol "Actin filaments" "CAB017111: , HPA051322: " "unprognostic (3.80e-2)" "unprognostic (1.19e-2)" "unprognostic (2.03e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.90e-1)" "unprognostic (1.98e-1)" "unprognostic (1.98e-3)" "unprognostic (6.10e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (2.19e-4)" "unprognostic (2.86e-1)" "unprognostic (6.13e-2)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (5.99e-4)" "unprognostic (2.75e-1)" "unprognostic (2.08e-2)" "unprognostic (4.11e-1)" "unprognostic (2.11e-1)" "unprognostic (7.24e-2)" "unprognostic (3.09e-2)" "unprognostic (3.04e-1)" "unprognostic (1.13e-1)" "unprognostic (1.68e-1)" "unprognostic (1.09e-2)" "unprognostic (2.10e-2)" "unprognostic (9.72e-2)" "unprognostic (6.77e-2)" "unprognostic (1.70e-1)" "unprognostic (3.23e-2)" CTPS2 GATD5B ENSG00000047230 "CTP synthase 2" Q9NRF8 X 16587999-16712936 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyrimidine biosynthesis" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA017437, HPA075930" Approved Approved Mitochondria,Cytosol NA NA 30000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 40 "Mitochondria, Cytosol" "HPA017437: , HPA075930: " "unprognostic (2.16e-1)" "unprognostic (1.04e-2)" "unprognostic (1.14e-1)" "unprognostic (1.56e-1)" "unprognostic (2.04e-1)" "unprognostic (7.16e-2)" "unprognostic (1.31e-1)" "unprognostic (5.44e-2)" "unprognostic (1.28e-1)" "unprognostic (3.79e-1)" "unprognostic (1.96e-3)" "unprognostic (2.78e-3)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.62e-5)" "unprognostic (3.08e-2)" "unprognostic (8.15e-2)" "unprognostic (7.15e-2)" "unprognostic (5.19e-3)" "unprognostic (1.30e-1)" "unprognostic (8.97e-2)" "unprognostic (2.31e-1)" "unprognostic (2.30e-2)" "unprognostic (2.97e-1)" "unprognostic (1.27e-2)" "unprognostic (7.62e-3)" "unprognostic (5.37e-2)" "unprognostic (2.61e-2)" "unprognostic (4.35e-1)" "unprognostic (2.53e-1)" "unprognostic (1.46e-2)" "unprognostic (1.59e-1)" CTR9 "KIAA0155, p150TSP, SH2BP1, TSBP" ENSG00000198730 "CTR9 homolog, Paf1/RNA polymerase II complex component" Q6PD62 11 10751246-10801625 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "pancreas: 5183219.3" "HPA061027, HPA068122" Supported Enhanced Nucleoplasm No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 73 Nucleoplasm "HPA061027: , HPA068122: " "unprognostic (1.12e-1)" "unprognostic (1.10e-1)" "unprognostic (2.52e-2)" "unprognostic (5.15e-3)" "unprognostic (2.98e-1)" "unprognostic (8.40e-3)" "unprognostic (4.74e-2)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (3.69e-1)" "potential prognostic unfavorable (3.20e-4)" "validated prognostic favorable (1.86e-7)" "validated prognostic favorable (2.73e-4)" "unprognostic (1.40e-1)" "unprognostic (7.92e-2)" "unprognostic (2.19e-2)" "unprognostic (3.15e-1)" "unprognostic (4.19e-2)" "unprognostic (1.88e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (9.15e-4)" "unprognostic (2.78e-2)" "unprognostic (6.02e-3)" "unprognostic (3.21e-2)" "unprognostic (1.60e-2)" "unprognostic (1.78e-2)" "unprognostic (2.02e-1)" "unprognostic (8.17e-2)" "unprognostic (2.87e-1)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" CTSA "GSL, PPGB" ENSG00000064601 "Cathepsin A" P10619 20 45890144-45898949 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 312.4" "Cell type enriched" "Detected in all" 6 "Platelets: 2264.3" "Cell type enriched" "Detected in all" 6 "Platelets: 2264.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 20209318.6" "Low tissue specificity" "Detected in all" "CAB024930, HPA031068, HPA072487" Enhanced Enhanced Vesicles "Intracellular and membrane" Enzyme NA NA 31000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 47: Platelets - Hemostasis" 13 Vesicles "CAB024930: , HPA031068: , HPA072487: " "unprognostic (2.70e-1)" "potential prognostic unfavorable (9.10e-4)" "unprognostic (5.61e-2)" "unprognostic (1.48e-1)" "unprognostic (2.57e-1)" "unprognostic (6.46e-2)" "unprognostic (8.79e-2)" "unprognostic (2.60e-2)" "unprognostic (8.34e-2)" "unprognostic (9.60e-2)" "unprognostic (4.47e-3)" "unprognostic (6.59e-3)" "unprognostic (4.17e-1)" "potential prognostic unfavorable (1.96e-6)" "unprognostic (2.38e-2)" "unprognostic (1.06e-1)" "unprognostic (5.55e-2)" "unprognostic (1.47e-2)" "unprognostic (7.50e-3)" "unprognostic (2.36e-2)" "unprognostic (3.57e-2)" "unprognostic (2.55e-1)" "unprognostic (2.65e-1)" "unprognostic (1.57e-1)" "unprognostic (2.91e-1)" "unprognostic (3.80e-2)" "unprognostic (1.51e-2)" "unprognostic (1.28e-1)" "unprognostic (2.17e-2)" "unprognostic (6.29e-2)" "unprognostic (3.30e-3)" CTSB ENSG00000164733 "Cathepsin B" P07858 8 11842524-11869533 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 991.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 409.7;Hofbauer cells: 627.2;Kupffer cells: 1672.7;Macrophages: 437.5;Microglia: 369.8;monocytes: 390.0;Syncytiotrophoblasts: 298.2" "Cell type enriched" "Detected in all" 4 "Mononuclear phagocytes: 1672.7" "Cell type enriched" "Detected in all" 6 "central nervous system macrophage: 499.5" "Cancer enriched" "Detected in all" 4 "Thyroid Carcinoma (TCGA): 2281.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 389.7;classical monocyte: 610.5;intermediate monocyte: 467.6;myeloid DC: 287.7;non-classical monocyte: 309.1;plasmacytoid DC: 410.8" "Group enriched" "Detected in all" 6 "dendritic cells: 410.8;granulocytes: 389.7;monocytes: 610.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 14530706.0" "Low tissue specificity" "Detected in all" "CAB000457, HPA018156, HPA048998" Enhanced Supported Nucleoli,Vesicles "Secreted to blood" Enzyme NA NA 524000000 42000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 74 Vesicles Nucleoli "CAB000457: , HPA018156: , HPA048998: " "unprognostic (4.69e-2)" "unprognostic (3.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.48e-2)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (2.58e-3)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (1.72e-4)" "potential prognostic favorable (1.04e-5)" "unprognostic (1.69e-2)" "unprognostic (7.41e-3)" "unprognostic (1.16e-1)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (2.36e-3)" "unprognostic (5.03e-2)" "unprognostic (2.92e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (1.18e-2)" "unprognostic (1.89e-1)" "unprognostic (7.61e-2)" "unprognostic (5.33e-2)" "unprognostic (2.65e-2)" "unprognostic (2.62e-1)" "unprognostic (2.65e-1)" "unprognostic (7.41e-2)" "unprognostic (4.70e-2)" "unprognostic (5.08e-2)" CTSC "DPP1, PALS, PLS" ENSG00000109861 "Cathepsin C" P53634 11 88265069-88359684 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 535.3;Decidual stromal cells: 477.4;Hofbauer cells: 2040.8;Kupffer cells: 597.5;Macrophages: 530.8;pDCs: 544.2;Respiratory secretory cells: 627.1" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 2040.8" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 259.7;leukocyte: 161.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Lung - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 31836749.1;Proximal tubules: 29926959.6" "Tissue enhanced" "Detected in all" "kidney: 167916625.0" "CAB025364, HPA066610, HPA068434" Enhanced Supported Vesicles "Intracellular and membrane" Enzyme No No 12000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 Vesicles "CAB025364: , HPA066610: , HPA068434: " "potential prognostic unfavorable (1.04e-5)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (2.16e-1)" "unprognostic (5.51e-2)" "unprognostic (1.93e-1)" "unprognostic (4.28e-3)" "unprognostic (9.27e-2)" "unprognostic (7.25e-3)" "unprognostic (4.08e-3)" "unprognostic (7.67e-3)" "unprognostic (2.92e-2)" "unprognostic (8.80e-2)" "potential prognostic unfavorable (6.04e-5)" "unprognostic (7.66e-3)" "unprognostic (2.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.46e-1)" "unprognostic (1.35e-1)" "unprognostic (4.46e-2)" "unprognostic (1.21e-1)" "unprognostic (3.96e-2)" "unprognostic (1.73e-1)" "unprognostic (3.55e-1)" "unprognostic (7.26e-2)" "unprognostic (4.89e-2)" "unprognostic (1.31e-1)" "unprognostic (3.31e-1)" "unprognostic (2.06e-1)" "unprognostic (1.52e-1)" "unprognostic (1.44e-1)" CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 599.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 136.4;Esophageal apical cells: 614.8;Extravillous trophoblasts: 211.5;Medullary thymic epithelial cells: 650.5;Migrating cytotrophoblasts: 216.2;Ocular epithelial cells: 976.3;Sertoli cells: 249.2" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 614.8;Barrier epithelial cells: 976.3;Secretory gland support: 650.5" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 5.5;oligodendrocyte: 4.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.2" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.2" "Cancer enriched" "Detected in all" 7 "testis cancer: 681.3" "Kidney - Proximal tubular cells, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 31828 "Keratinocytes: 3182824.0" "Tissue enhanced" "Detected in all" "intestine: 33837907.2" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 300000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 27 "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (4.13e-3)" "unprognostic (2.90e-1)" "unprognostic (3.06e-2)" "unprognostic (3.64e-2)" "unprognostic (7.95e-2)" "unprognostic (1.28e-1)" "unprognostic (6.71e-3)" "unprognostic (1.24e-1)" "unprognostic (8.27e-3)" "unprognostic (3.13e-2)" "unprognostic (5.97e-2)" "potential prognostic unfavorable (5.59e-4)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (2.60e-2)" "unprognostic (2.65e-2)" "unprognostic (3.11e-1)" "unprognostic (4.71e-2)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (2.85e-3)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (2.01e-1)" "unprognostic (1.93e-1)" "unprognostic (1.57e-2)" "unprognostic (1.74e-1)" "unprognostic (1.51e-3)" "unprognostic (6.63e-2)" CTSZ CTSX ENSG00000101160 "Cathepsin Z" Q9UBR2 20 58985686-59008238 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "cDC: 681.9;Hepatocytes: 431.0;Hofbauer cells: 1473.3;Kupffer cells: 483.8;Macrophages: 639.8;monocytes: 531.2;pDCs: 460.9" "Cell type enhanced" "Detected in all" "dendritic cells: 681.9;Mononuclear phagocytes: 1473.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 143.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 55487345.4" "Low tissue specificity" "Detected in all" "CAB025114, HPA049876, HPA053504" Supported Supported Vesicles "Intracellular and membrane" Enzyme NA NA 22000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 17 Vesicles "CAB025114: , HPA049876: , HPA053504: " "unprognostic (3.42e-1)" "unprognostic (3.54e-1)" "unprognostic (1.43e-1)" "unprognostic (2.25e-3)" "unprognostic (2.10e-1)" "unprognostic (8.04e-2)" "unprognostic (3.21e-2)" "unprognostic (1.32e-1)" "unprognostic (8.36e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-3)" "unprognostic (7.50e-2)" "unprognostic (4.01e-1)" "unprognostic (2.40e-2)" "unprognostic (7.29e-2)" "unprognostic (6.38e-3)" "unprognostic (2.63e-2)" "unprognostic (5.37e-2)" "unprognostic (2.68e-1)" "unprognostic (8.39e-2)" "unprognostic (5.27e-2)" "unprognostic (5.58e-2)" "unprognostic (3.44e-2)" "unprognostic (3.45e-1)" "unprognostic (7.27e-2)" "unprognostic (2.11e-2)" "unprognostic (3.69e-2)" "unprognostic (1.48e-1)" "unprognostic (4.76e-2)" "unprognostic (7.47e-3)" "unprognostic (2.37e-1)" CTTNBP2 "C7orf8, CORTBP2, KIAA1758, Orf4" ENSG00000077063 "Cortactin binding protein 2" Q8WZ74 7 117710651-117874139 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 277.2;Choroid plexus epithelial cells: 265.4;Epididymal clear cells: 265.4;Mast cells: 355.4;Microglia: 299.7;Müller glia: 242.8;Oligodendrocyte progenitor cells: 601.7;Oligodendrocytes: 459.3;Podocytes: 315.9;Proximal tubule cells: 290.3;Retinal amacrine cells: 307.1;Retinal horizontal cells: 230.4" "Cell type enhanced" "Detected in many" "Glial cells: 601.7;Mast cells: 355.4;Neuronal cells: 307.1;Renal nephron cells: 315.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 18.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 9 "non-classical monocyte: 7.9" "Lineage enriched" "Detected in single" 26 "monocytes: 7.9" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 1062381.2;Large ducts: 607945.9;Microglia and Neuropil: 2170101.1;Neurons: 728471.5" "Group enriched" "Detected in some" 7838 "cerebral cortex: 586424.6;intestine: 981186.3" "CAB009151, HPA044654" Enhanced Approved "Midbody ring,Cytosol" Yes No "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 49: HMC-1 - Innate immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 32 "Midbody ring" Cytosol "CAB009151: , HPA044654: " "unprognostic (1.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (1.07e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (5.92e-2)" "unprognostic (6.18e-3)" "unprognostic (2.60e-2)" "potential prognostic favorable (9.94e-4)" "unprognostic (6.39e-2)" "unprognostic (4.41e-2)" "unprognostic (9.11e-2)" "unprognostic (7.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.14e-3)" "unprognostic (1.72e-1)" "unprognostic (2.17e-1)" "unprognostic (1.40e-1)" "unprognostic (6.08e-3)" "unprognostic (9.73e-2)" "unprognostic (3.53e-1)" "unprognostic (2.86e-2)" "unprognostic (1.05e-1)" "unprognostic (1.23e-1)" "unprognostic (6.39e-2)" "unprognostic (7.64e-2)" "unprognostic (3.50e-2)" CTTNBP2NL DKFZp547A023 ENSG00000143079 "CTTNBP2 N-terminal like" Q9P2B4 1 112396214-112463456 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 243.2;Esophageal apical cells: 376.9;Microglia: 346.1" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 376.9;Glial cells: 346.1" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 428.6;endothelial cell: 294.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 8.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 6634241.4" "Tissue enhanced" "Detected in some" "ovary: 5747309.5" HPA007301 Approved Approved "Nucleoli fibrillar center,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 58 "Nucleoli fibrillar center, Cytosol" "HPA007301: " "unprognostic (2.73e-2)" "unprognostic (1.29e-1)" "unprognostic (1.67e-1)" "unprognostic (2.88e-2)" "potential prognostic favorable (2.46e-4)" "unprognostic (1.60e-2)" "unprognostic (2.08e-2)" "unprognostic (2.55e-1)" "unprognostic (1.15e-1)" "unprognostic (3.01e-2)" "validated prognostic favorable (2.47e-8)" "validated prognostic favorable (2.93e-6)" "unprognostic (1.91e-1)" "unprognostic (1.91e-2)" "unprognostic (2.63e-1)" "unprognostic (2.01e-1)" "unprognostic (4.30e-3)" "unprognostic (1.03e-1)" "unprognostic (2.77e-1)" "unprognostic (3.42e-2)" "unprognostic (2.92e-3)" "unprognostic (2.11e-3)" "unprognostic (4.06e-2)" "unprognostic (2.47e-2)" "potential prognostic favorable (7.68e-5)" "unprognostic (1.65e-1)" "unprognostic (4.67e-2)" "unprognostic (3.10e-1)" "unprognostic (3.87e-1)" "unprognostic (2.15e-2)" "unprognostic (5.44e-2)" CUEDC1 ENSG00000180891 "CUE domain containing 1" Q9NWM3 17 57861243-57955412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 205.4;Cone photoreceptor cells: 223.6;Rod photoreceptor cells: 263.0" "Cell type enhanced" "Detected in all" "Neuronal cells: 263.0" "Cell type enhanced" "Detected in all" "oligodendrocyte: 222.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 21.8" "Lineage enriched" "Detected in many" 9 "dendritic cells: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Capillaries: 820370.6;Cardiomyocytes: 359517.8;Fallopian tube cells: 572657.7" "Tissue enriched" "Detected in many" "heart muscle: 2168416.3" "HPA023050, HPA024836" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" Yes NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 35 "Plasma membrane, Primary cilium, Centrosome, Basal body" "Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium tip, Cytosol" "HPA023050: , HPA024836: " "unprognostic (4.30e-2)" "unprognostic (5.41e-2)" "unprognostic (2.90e-1)" "unprognostic (2.92e-2)" "unprognostic (7.39e-2)" "unprognostic (1.45e-1)" "unprognostic (1.90e-1)" "potential prognostic favorable (5.67e-4)" "unprognostic (1.24e-1)" "unprognostic (1.08e-3)" "potential prognostic favorable (2.17e-5)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "validated prognostic unfavorable (4.65e-4)" "validated prognostic unfavorable (5.25e-4)" "unprognostic (1.73e-1)" "unprognostic (4.39e-3)" "unprognostic (2.13e-1)" "unprognostic (2.72e-2)" "unprognostic (3.69e-2)" "unprognostic (8.11e-2)" "unprognostic (6.48e-2)" "unprognostic (3.50e-2)" "unprognostic (3.37e-1)" "unprognostic (2.84e-1)" "unprognostic (8.06e-3)" "unprognostic (3.50e-2)" "unprognostic (2.26e-1)" "unprognostic (3.19e-2)" "unprognostic (3.75e-3)" "unprognostic (1.21e-2)" CUEDC2 "C10orf66, MGC2491" ENSG00000107874 "CUE domain containing 2" Q9H467 10 102423245-102432584 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 672594.5;Large ducts: 880574.2" "Tissue enriched" "Detected in some" "cerebral cortex: 695973.1" "HPA036544, HPA041829" Uncertain Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Primary cilium tip,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 14 "Nucleoplasm, Cytosol" "Nuclear membrane, Plasma membrane, Primary cilium tip" "HPA036544: , HPA041829: " "unprognostic (1.15e-1)" "unprognostic (9.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.25e-1)" "unprognostic (5.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (3.76e-4)" "unprognostic (1.06e-1)" "unprognostic (1.99e-2)" "potential prognostic favorable (3.53e-4)" "unprognostic (2.25e-1)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (5.31e-5)" "unprognostic (3.23e-1)" "unprognostic (2.83e-1)" "unprognostic (4.30e-2)" "unprognostic (7.71e-2)" "unprognostic (1.47e-1)" "unprognostic (1.98e-1)" "unprognostic (1.57e-1)" "unprognostic (9.01e-2)" "unprognostic (1.19e-1)" "unprognostic (7.36e-2)" "unprognostic (2.24e-1)" "potential prognostic favorable (5.60e-4)" "unprognostic (6.51e-2)" "unprognostic (1.88e-1)" "unprognostic (3.81e-1)" "unprognostic (7.59e-2)" "unprognostic (1.40e-2)" CUL1 ENSG00000055130 "Cullin 1" Q13616 7 148697914-148801110 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 579.8;Late spermatids: 949.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 949.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "CAB002676, HPA029882, HPA064584" Supported Approved Nucleoplasm,Nucleoli,Cytosol NA NA 170000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 241 Nucleoplasm "Nucleoli, Cytosol" "CAB002676: , HPA029882: , HPA064584: " "unprognostic (3.93e-2)" "unprognostic (1.15e-1)" "unprognostic (6.93e-2)" "unprognostic (9.15e-2)" "unprognostic (6.28e-2)" "unprognostic (1.80e-3)" "unprognostic (6.57e-2)" "unprognostic (3.84e-2)" "unprognostic (2.34e-1)" "unprognostic (1.85e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (1.77e-2)" "unprognostic (6.35e-2)" "unprognostic (8.47e-3)" "unprognostic (4.11e-3)" "unprognostic (4.19e-3)" "unprognostic (5.99e-2)" "unprognostic (6.68e-2)" "unprognostic (1.26e-1)" "unprognostic (3.74e-2)" "unprognostic (1.32e-1)" "unprognostic (2.65e-1)" "unprognostic (3.18e-1)" "unprognostic (7.41e-2)" "unprognostic (2.26e-1)" "unprognostic (2.27e-1)" "unprognostic (6.23e-2)" "unprognostic (1.64e-1)" "unprognostic (1.41e-1)" "unprognostic (1.37e-1)" "unprognostic (3.02e-1)" CUL3 ENSG00000036257 "Cullin 3" Q13618 2 224470150-224585397 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, ER-Golgi transport, Mitosis, Transport, Ubl conjugation pathway" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 193.0" "Cell type enhanced" "Detected in all" "Neutrophils: 728.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB002678, HPA072059" Supported Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA 69000 "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 858 Nucleoplasm "Microtubules, Cytokinetic bridge" "CAB002678: , HPA072059: " "unprognostic (1.54e-2)" "unprognostic (1.24e-3)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (2.04e-1)" "unprognostic (1.06e-1)" "unprognostic (1.53e-1)" "unprognostic (4.41e-1)" "unprognostic (2.77e-1)" "unprognostic (4.77e-3)" "validated prognostic favorable (8.06e-6)" "validated prognostic favorable (8.36e-4)" "unprognostic (1.77e-1)" "unprognostic (5.77e-3)" "unprognostic (1.23e-2)" "unprognostic (2.69e-2)" "unprognostic (1.84e-1)" "unprognostic (2.14e-1)" "unprognostic (1.11e-1)" "unprognostic (6.65e-2)" "unprognostic (1.21e-1)" "unprognostic (1.65e-2)" "unprognostic (8.12e-2)" "unprognostic (1.20e-1)" "unprognostic (7.76e-2)" "unprognostic (9.87e-2)" "unprognostic (2.72e-3)" "unprognostic (1.14e-1)" "unprognostic (4.49e-2)" "unprognostic (1.38e-1)" "unprognostic (3.16e-1)" CUL9 "H7AP1, KIAA0708, PARC" ENSG00000112659 "Cullin 9" Q8IWT3 6 43182184-43224587 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 19 "Early spermatids: 684.4;Late spermatids: 2360.0" "Cell type enriched" "Detected in many" 88 "Spermatogenic cell types: 2360.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 162789.3" "HPA016434, HPA052004" Approved Approved Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 11 Cytosol "HPA016434: , HPA052004: " "unprognostic (1.44e-1)" "unprognostic (5.05e-2)" "unprognostic (1.04e-1)" "unprognostic (3.42e-2)" "unprognostic (7.17e-2)" "unprognostic (1.35e-1)" "unprognostic (1.17e-1)" "unprognostic (7.67e-3)" "potential prognostic favorable (1.85e-4)" "unprognostic (3.51e-2)" "potential prognostic favorable (7.82e-7)" "unprognostic (6.11e-3)" "unprognostic (2.92e-2)" "unprognostic (4.13e-2)" "unprognostic (4.22e-1)" "unprognostic (3.58e-2)" "unprognostic (1.27e-1)" "unprognostic (1.01e-1)" "unprognostic (4.55e-2)" "unprognostic (7.70e-2)" "potential prognostic favorable (9.25e-4)" "unprognostic (2.48e-1)" "unprognostic (2.83e-2)" "unprognostic (3.51e-1)" "unprognostic (1.04e-2)" "unprognostic (1.10e-1)" "unprognostic (1.37e-1)" "unprognostic (1.76e-1)" "unprognostic (2.28e-1)" "unprognostic (2.07e-2)" "unprognostic (1.41e-1)" CUTC CGI-32 ENSG00000119929 "CutC copper transporter" Q9NTM9 10 99702558-99756134 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 361.4;tongue: 190.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 191.1;Late primary spermatocytes: 185.8;Myonuclei: 339.8" "Cell type enhanced" "Detected in all" "Myocytes: 339.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 16920720.6;Skeletal myofibers: 20994179.0" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7598394.7;skeletal muscle: 11663068.4" "HPA038619, HPA058231" Enhanced Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 "Nucleoplasm, Cytosol" Nucleoli "HPA038619: , HPA058231: " "unprognostic (1.64e-1)" "unprognostic (1.50e-2)" "unprognostic (4.27e-1)" "unprognostic (3.08e-2)" "unprognostic (1.86e-2)" "unprognostic (2.09e-1)" "unprognostic (8.25e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (3.03e-2)" "unprognostic (1.95e-1)" "unprognostic (8.72e-2)" "unprognostic (1.77e-1)" "unprognostic (2.14e-2)" "unprognostic (2.53e-3)" "unprognostic (5.98e-2)" "unprognostic (7.90e-3)" "unprognostic (1.39e-1)" "unprognostic (1.43e-1)" "unprognostic (9.18e-2)" "unprognostic (8.46e-2)" "unprognostic (8.48e-3)" "unprognostic (2.78e-1)" "unprognostic (8.30e-2)" "unprognostic (1.41e-1)" "unprognostic (3.27e-1)" "unprognostic (1.75e-2)" "unprognostic (2.70e-2)" "unprognostic (1.00e-1)" "unprognostic (3.99e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-3)" CWC27 "NY-CO-10, SDCCAG-10, SDCCAG10" ENSG00000153015 "CWC27 spliceosome associated cyclophilin" Q6UX04 5 64766368-65102412 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dwarfism, Intellectual disability, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 412.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 412.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 3340883.6;Neurons: 2332774.9" "Tissue enhanced" "Detected in many" "Stomach: 4540494.9" "HPA020344, HPA024149, HPA065809" Approved Enhanced Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA020344: , HPA024149: , HPA065809: " "unprognostic (1.16e-1)" "unprognostic (9.99e-2)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (3.71e-2)" "unprognostic (1.32e-1)" "unprognostic (5.67e-2)" "unprognostic (8.60e-2)" "unprognostic (4.14e-2)" "unprognostic (3.41e-2)" "unprognostic (9.04e-3)" "potential prognostic favorable (2.50e-6)" "unprognostic (3.04e-2)" "unprognostic (3.17e-1)" "validated prognostic unfavorable (2.60e-4)" "validated prognostic unfavorable (1.69e-4)" "potential prognostic unfavorable (9.67e-4)" "unprognostic (9.71e-2)" "unprognostic (2.10e-1)" "unprognostic (1.88e-1)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (8.79e-3)" "unprognostic (1.91e-3)" "unprognostic (3.75e-2)" "unprognostic (3.19e-2)" "unprognostic (1.72e-1)" "unprognostic (8.11e-2)" "unprognostic (5.00e-2)" "unprognostic (6.09e-2)" "unprognostic (1.71e-2)" "unprognostic (5.80e-2)" CXCL8 "3-10C, AMCF-I, b-ENAP, GCP-1, GCP1, IL-8, IL8, K60, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1, SCYB8, TSG-1" ENSG00000169429 "C-X-C motif chemokine ligand 8" P10145 4 73740519-73743716 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "bone marrow: 2989.3" "Cell type enhanced" "Detected in many" "cDC: 5291.0;Endometrial glandular cells: 1898.1;Endometrial secretory cells: 2945.1;Epididymal basal cells: 12468.0;Epididymal efferent duct absorptive cells: 2558.5;Macrophages: 2070.2;monocytes: 3941.4;Neutrophils: 6690.9" "Cell type enhanced" "Detected in many" "Basal cells: 12468.0;dendritic cells: 5291.0;Mononuclear phagocytes: 3941.4;Neutrophils: 6690.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.4;endothelial cell: 9.7;fibroblast: 3.7" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 10 "cerebral cortex: 274.2" "Immune cell enriched" "Detected in some" 408 "neutrophil: 439.6" "Lineage enriched" "Detected in single" 1040 "granulocytes: 439.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 314.5" "Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA057179 Supported Approved "Golgi apparatus" "Secreted to blood" Chemokine NA NA 7260 "Cluster 4: Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 6 "Golgi apparatus" "HPA057179: " "unprognostic (3.23e-1)" "unprognostic (9.00e-2)" "potential prognostic unfavorable (6.85e-7)" "unprognostic (1.88e-2)" "unprognostic (5.06e-2)" "unprognostic (2.03e-2)" "unprognostic (1.31e-3)" "unprognostic (2.08e-3)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (4.03e-3)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.31e-5)" "unprognostic (2.84e-2)" "unprognostic (1.69e-3)" "unprognostic (1.91e-2)" "unprognostic (4.43e-2)" "unprognostic (1.39e-1)" "unprognostic (3.04e-2)" "unprognostic (1.21e-2)" "unprognostic (2.77e-2)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.43e-1)" "unprognostic (6.43e-2)" "unprognostic (6.63e-2)" "unprognostic (1.95e-2)" "unprognostic (2.11e-1)" CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 25.7;lymphoid tissue: 40.8" "Cell type enriched" "Detected in some" 13 "Neutrophils: 1412.1" "Cell type enriched" "Detected in some" 13 "Neutrophils: 1412.1" "Group enriched" "Detected in some" 14 "central nervous system macrophage: 1.3;leukocyte: 4.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3297.5" "Lineage enriched" "Detected in many" 109 "granulocytes: 3297.5" "Cancer enriched" "Detected in single" 9 "Leukemia: 6.9" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB016268, HPA031999, HPA032017, CAB080545" Enhanced Approved "Vesicles,Plasma membrane,Microtubules,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 13 "Plasma membrane" "Vesicles, Microtubules, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body" "CAB016268: , CAB080545: , HPA031999: , HPA032017: " "unprognostic (1.85e-2)" "unprognostic (2.82e-3)" "unprognostic (2.27e-2)" "unprognostic (3.32e-2)" "unprognostic (9.35e-3)" "unprognostic (7.78e-2)" "unprognostic (3.08e-1)" "unprognostic (1.12e-1)" "unprognostic (1.16e-2)" "unprognostic (1.71e-1)" "unprognostic (7.00e-3)" "unprognostic (8.57e-2)" "unprognostic (1.35e-1)" "unprognostic (4.02e-1)" "unprognostic (1.98e-1)" "unprognostic (2.39e-2)" "unprognostic (1.39e-1)" "unprognostic (5.72e-2)" CXorf58 FLJ25444 ENSG00000165182 "Chromosome X open reading frame 58" Q96LI9 X 23908006-23939509 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 8 "testis: 3.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 10.8;Early primary spermatocytes: 29.1;Early spermatids: 21.3;Hematopoietic stem cells: 9.7;Late primary spermatocytes: 42.4;Late spermatids: 9.1;Undifferentiated spermatogonia: 11.0" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 42.4" "Cell type enhanced" "Detected in many" "ependymal cell: 6.6;leukocyte: 8.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031542, HPA031543, HPA031544" Uncertain Approved Nucleoplasm NA NA "Cluster 47: Testis - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 Nucleoplasm "HPA031542: , HPA031543: , HPA031544: " CXorf66 "RP11-35F15.2, SGPX" ENSG00000203933 "Chromosome X open reading frame 66" Q5JRM2 X 139955728-139965521 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 22 "testis: 12.7" "Group enriched" "Detected in some" 7 "Early spermatids: 135.4;Late primary spermatocytes: 95.5" "Cell type enriched" "Detected in single" 272 "Spermatogenic cell types: 135.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048517 Approved "Perinuclear theca,Calyx,Mid piece,Principal piece,End piece,Annulus" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 9 "Perinuclear theca, Calyx, Annulus" "Mid piece, Principal piece, End piece" "HPA048517: " CYB5A CYB5 ENSG00000166347 "Cytochrome b5 type A" P00167 18 74250846-74291973 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 828.0;liver: 2306.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 2211.1;Breast lactating cells: 1374.0;Enterocytes: 1661.0;Hepatocytes: 3986.6;Transitional alveolar cells: 1918.9;Urothelial cells: 1103.3" "Cell type enhanced" "Detected in all" "Alveolar cells: 2211.1;Enterocytes: 1661.0;Hepatocytes: 3986.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cell types: 287338759.3;Hepatocytes: 499166551.5;Proximal tubules: 335788335.0" "Group enriched" "Detected in all" "kidney: 703484958.1;liver: 1958856379.8" "CAB006333, HPA047548, HPA058547" Enhanced Enhanced Vesicles,Cytosol No No 1200000 "Cluster 34: B-cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 26 "Vesicles, Cytosol" "CAB006333: , HPA047548: , HPA058547: " "unprognostic (2.30e-2)" "unprognostic (3.74e-2)" "unprognostic (5.91e-2)" "unprognostic (8.83e-2)" "potential prognostic favorable (6.47e-4)" "unprognostic (4.84e-2)" "unprognostic (2.37e-1)" "potential prognostic favorable (6.91e-6)" "unprognostic (7.48e-2)" "unprognostic (9.63e-2)" "potential prognostic favorable (1.78e-7)" "unprognostic (2.37e-2)" "potential prognostic favorable (2.51e-4)" "validated prognostic favorable (3.82e-4)" "validated prognostic favorable (7.90e-4)" "unprognostic (5.67e-3)" "unprognostic (1.28e-1)" "unprognostic (9.60e-3)" "unprognostic (8.45e-2)" "unprognostic (1.56e-1)" "unprognostic (1.30e-1)" "unprognostic (3.66e-3)" "unprognostic (1.13e-2)" "unprognostic (2.32e-2)" "unprognostic (2.91e-2)" "unprognostic (3.01e-2)" "unprognostic (7.53e-2)" "unprognostic (1.80e-1)" "unprognostic (4.60e-1)" "unprognostic (1.90e-1)" "unprognostic (7.90e-3)" CYB5R1 "humb5R2, NQO3A2" ENSG00000159348 "Cytochrome b5 reductase 1" Q9UHQ9 1 202961873-202967275 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 591.7" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 269.3;Migrating cytotrophoblasts: 348.3;Myonuclei: 194.0;Parietal cells: 249.3;Platelets: 304.7;Syncytiotrophoblasts: 388.8" "Cell type enhanced" "Detected in all" "Platelets: 304.7;Trophoblast cells: 388.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Keratinocyte (other), Stomach - Parietal cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 341369200.8" "Tissue enhanced" "Detected in all" "skeletal muscle: 137172650.8" "HPA010531, HPA010641, HPA014147" Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 15 Mitochondria Cytosol "HPA010531: , HPA010641: , HPA014147: " "unprognostic (1.57e-2)" "unprognostic (3.62e-2)" "unprognostic (1.73e-1)" "unprognostic (8.22e-3)" "unprognostic (6.31e-2)" "unprognostic (6.31e-3)" "unprognostic (1.22e-3)" "unprognostic (7.98e-3)" "unprognostic (7.81e-3)" "unprognostic (6.65e-2)" "potential prognostic favorable (4.83e-7)" "unprognostic (1.83e-2)" "unprognostic (3.24e-1)" "unprognostic (2.42e-2)" "unprognostic (1.15e-1)" "unprognostic (6.04e-3)" "unprognostic (1.13e-1)" "unprognostic (1.18e-2)" "unprognostic (6.68e-3)" "unprognostic (1.06e-1)" "unprognostic (1.11e-2)" "unprognostic (1.28e-1)" "unprognostic (5.91e-2)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (1.63e-1)" "unprognostic (2.44e-1)" "unprognostic (3.08e-1)" "unprognostic (1.41e-1)" "unprognostic (1.83e-2)" "unprognostic (1.14e-2)" CYC1 UQCR4 ENSG00000179091 "Cytochrome c1" P08574 8 144095039-144097525 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 684.3;tongue: 676.8" "Cell type enhanced" "Detected in many" "Colonocytes: 554.8;Enteric stem cells: 468.6;Enteric transient amplifying cells: 632.2;Enterocytes: 490.4;Esophageal basal cells: 706.9;Esophageal suprabasal cells: 605.9;Parietal cells: 595.8" "Cell type enhanced" "Detected in all" "Basal cells: 706.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 241436316.2" "Tissue enriched" "Detected in all" "heart muscle: 335817634.7" HPA001247 Supported Approved "Mitochondria,Equatorial segment" NA NA 76000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 27 Mitochondria "Equatorial segment" "HPA001247: " "unprognostic (3.11e-1)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (7.22e-2)" "unprognostic (2.17e-1)" "unprognostic (3.31e-1)" "unprognostic (9.99e-2)" "unprognostic (3.36e-1)" "unprognostic (8.43e-3)" "unprognostic (6.31e-2)" "unprognostic (2.47e-2)" "potential prognostic favorable (8.14e-4)" "unprognostic (2.58e-1)" "unprognostic (2.52e-2)" "unprognostic (2.80e-1)" "unprognostic (2.03e-3)" "unprognostic (1.73e-3)" "unprognostic (1.20e-1)" "unprognostic (1.28e-1)" "unprognostic (2.02e-1)" "unprognostic (2.08e-1)" "unprognostic (5.10e-2)" "unprognostic (2.05e-1)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" "unprognostic (5.89e-2)" "unprognostic (3.38e-1)" "unprognostic (9.18e-2)" "unprognostic (2.84e-1)" "unprognostic (1.64e-1)" "unprognostic (2.20e-2)" "unprognostic (6.76e-2)" CYFIP2 PIR121 ENSG00000055163 "Cytoplasmic FMR1 interacting protein 2" Q96F07 5 157266079-157395595 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.2;kidney: 130.8" "Cell type enhanced" "Detected in many" "Corticotrophs: 260.5;Distal convoluted tubule cells: 404.4;Loop of henle epithelial cells: 519.8;Neutrophil progenitors: 422.9;Neutrophils: 606.9;Renal collecting duct principal cells: 363.8;Thymocytes: 272.7" "Cell type enhanced" "Detected in many" "Ductal cells: 363.8;Neutrophils: 606.9;Renal nephron cells: 519.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 78.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 173.5" "Adipose subcutaneous - Smooth muscle cells, Breast - T-cells, Kidney - Ascending Loop of Henle cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - B-cells (Spleen), Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 21622726.5;Microglia and Neuropil: 20999311.5;Neurons: 18415725.1" "Group enriched" "Detected in many" "cerebral cortex: 65141229.8;lymphoid tissue: 22549379.7" "CAB055519, HPA068106, HPA071459" Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 330000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 36: Brain & Liver - Signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 33 "Endoplasmic reticulum" "Plasma membrane, Cytosol" "CAB055519: , HPA068106: , HPA071459: " "unprognostic (2.85e-3)" "unprognostic (3.43e-2)" "unprognostic (1.28e-1)" "unprognostic (1.86e-1)" "unprognostic (1.08e-2)" "unprognostic (1.59e-2)" "unprognostic (2.07e-1)" "unprognostic (2.90e-2)" "unprognostic (1.72e-1)" "unprognostic (7.58e-2)" "potential prognostic favorable (2.81e-13)" "unprognostic (7.72e-3)" "unprognostic (1.85e-2)" "unprognostic (1.30e-1)" "unprognostic (7.76e-3)" "unprognostic (1.75e-3)" "unprognostic (3.44e-2)" "unprognostic (3.84e-2)" "unprognostic (2.68e-2)" "unprognostic (2.65e-1)" "unprognostic (1.07e-1)" "potential prognostic favorable (3.02e-4)" "unprognostic (4.11e-1)" "unprognostic (2.10e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-2)" "unprognostic (3.04e-2)" "unprognostic (1.54e-1)" "unprognostic (9.57e-2)" "unprognostic (8.00e-2)" "unprognostic (4.60e-2)" CYLD "CYLD1, KIAA0849, USPL2" ENSG00000083799 "CYLD lysine 63 deubiquitinase" Q9NQC7 16 50742050-50801935 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.0" "Cell type enhanced" "Detected in many" "Neutrophils: 361.8" "Cell type enhanced" "Detected in many" "Neutrophils: 361.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 19073054.2" "Tissue enhanced" "Detected in many" "intestine: 9463020.4;lymphoid tissue: 9301126.6" "CAB011713, HPA050095, HPA077163" Approved Supported "Nucleoplasm,Primary cilium transition zone,Centriolar satellite,Basal body,Principal piece" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 82: Dendritic cells - Antigen presentation" 141 "Centriolar satellite" "Nucleoplasm, Primary cilium transition zone, Basal body, Principal piece" "CAB011713: , HPA050095: , HPA077163: " "unprognostic (4.08e-2)" "unprognostic (2.28e-1)" "unprognostic (5.67e-3)" "unprognostic (1.24e-1)" "unprognostic (6.54e-2)" "unprognostic (6.35e-2)" "unprognostic (1.77e-1)" "unprognostic (2.53e-1)" "unprognostic (1.18e-1)" "unprognostic (5.58e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (6.53e-2)" "unprognostic (2.06e-1)" "unprognostic (7.95e-2)" "unprognostic (4.17e-3)" "unprognostic (1.87e-2)" "unprognostic (1.33e-1)" "unprognostic (6.64e-2)" "unprognostic (3.59e-1)" "unprognostic (7.34e-2)" "unprognostic (5.01e-3)" "unprognostic (1.55e-1)" "unprognostic (1.39e-2)" "unprognostic (2.06e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (8.86e-2)" "unprognostic (1.74e-1)" "unprognostic (7.56e-3)" "unprognostic (3.10e-1)" CYP19A1 "ARO, ARO1, aromatase, CPV1, CYAR, CYP19, P-450AROM" ENSG00000137869 "Cytochrome P450 family 19 subfamily A member 1" P11511 15 51208057-51338601 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes, Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "placenta: 117.1" "Cell type enriched" "Detected in many" 45 "Syncytiotrophoblasts: 5387.9" "Cell type enriched" "Detected in many" 45 "Trophoblast cells: 5387.9" "Cell type enhanced" "Detected in some" "medium spiny neuron: 4.6;thalamic excitatory: 10.8" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "lymphoma: 5.3;testis cancer: 15.0" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 7269 "Granulosa cells: 726933.4" "Not detected" "Not detected" "CAB000355, HPA051194" Enhanced Uncertain Mitochondria NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 17 Mitochondria "CAB000355: , HPA051194: " "unprognostic (2.17e-2)" "unprognostic (1.79e-2)" "unprognostic (2.29e-1)" "unprognostic (9.85e-2)" "unprognostic (1.23e-1)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (2.91e-6)" "unprognostic (2.22e-2)" "unprognostic (3.30e-1)" "unprognostic (5.17e-2)" "unprognostic (2.42e-1)" CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 94: Gonadal somatic cells - Mixed function" 3 "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: , HPA058461: " "unprognostic (6.53e-2)" "unprognostic (2.70e-2)" "unprognostic (4.65e-2)" "unprognostic (3.24e-2)" "unprognostic (2.61e-1)" "unprognostic (2.86e-1)" "unprognostic (1.44e-1)" "unprognostic (1.27e-2)" "unprognostic (1.35e-2)" "unprognostic (7.31e-2)" "unprognostic (2.01e-3)" "potential prognostic favorable (1.49e-4)" "unprognostic (1.97e-2)" "unprognostic (5.67e-2)" "unprognostic (1.26e-1)" "unprognostic (1.44e-2)" "unprognostic (8.16e-2)" "unprognostic (3.10e-2)" "unprognostic (2.37e-2)" "unprognostic (1.94e-1)" "unprognostic (1.31e-1)" "unprognostic (3.82e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (2.62e-2)" "unprognostic (2.50e-1)" "unprognostic (8.18e-3)" "unprognostic (2.56e-1)" "unprognostic (5.03e-1)" "unprognostic (2.59e-3)" "unprognostic (5.58e-3)" CYP24A1 "CP24, CYP24, lncBCAS1-4_1, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153446-54173986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 14.1;kidney: 31.6;lymphoid tissue: 9.9;placenta: 9.4;urinary bladder: 27.0" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 48.3;Basal prostatic cells: 17.4;Endometrial secretory cells: 88.5;Epididymal basal cells: 52.4;Loop of henle epithelial cells: 42.9;Ocular epithelial cells: 20.5;Papillary tip epithelial cells: 87.7;Proximal tubule cells: 23.3;Respiratory basal cells: 65.4;Suprabasal keratinocytes: 17.5;Urothelial cells: 35.1" "Cell type enhanced" "Detected in some" "Barrier epithelial cells: 35.1;Basal cells: 65.4;Renal nephron cells: 87.7;Secretory cells: 88.5" "Cell type enriched" "Detected in some" 4 "endothelial cell: 8.0" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 32.8;Lung Adenocarcinoma (TCGA): 40.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells (progenitors), Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Prostate - Urothelial cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Proximal tubules: 1903221.8" "Not detected" "Not detected" HPA022261 Enhanced Approved Mitochondria NA Yes "Cluster 11: T-cells - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 35 Mitochondria "HPA022261: " "unprognostic (1.60e-1)" "potential prognostic favorable (1.91e-8)" "unprognostic (1.11e-2)" "unprognostic (8.90e-2)" "unprognostic (1.43e-3)" "unprognostic (1.33e-2)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (1.75e-2)" "unprognostic (3.03e-1)" "unprognostic (1.09e-1)" "unprognostic (5.95e-2)" "unprognostic (5.03e-3)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (7.74e-3)" "unprognostic (2.47e-2)" "unprognostic (2.24e-2)" "unprognostic (7.22e-3)" CYP26B1 P450RAI-2 ENSG00000003137 "Cytochrome P450 family 26 subfamily B member 1" Q9NR63 2 72129238-72147862 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.6;skin 1: 29.6" "Group enriched" "Detected in many" 5 "Leydig cells: 110.6;Peritubular myoid cells: 235.8" "Group enriched" "Detected in many" 5 "Leydig cells: 110.6;Stromal cells: 235.8" "Group enriched" "Detected in many" 5 "deep-layer near-projecting: 39.4;lower rhombic lip: 62.9;upper rhombic lip: 22.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "pons: 111.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 38.6" "Breast - Adipocytes (Breast), Liver - Vascular endothelial cells, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 29113 "cerebral cortex: 2911345.2" HPA012567 Uncertain Approved Cytosol No No "Cluster 2: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 14 Cytosol "HPA012567: " "unprognostic (9.77e-2)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (1.16e-1)" "unprognostic (2.05e-1)" "unprognostic (1.37e-1)" "unprognostic (3.05e-2)" "unprognostic (5.50e-2)" "unprognostic (2.32e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "potential prognostic favorable (9.73e-5)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (4.86e-6)" "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (8.04e-2)" "unprognostic (2.23e-2)" "unprognostic (1.55e-2)" "unprognostic (3.87e-2)" "unprognostic (2.76e-1)" "unprognostic (2.61e-1)" "unprognostic (3.41e-1)" "unprognostic (2.69e-3)" "unprognostic (1.54e-1)" CYP27A1 "CP27, CTX, CYP27" ENSG00000135929 "Cytochrome P450 family 27 subfamily A member 1" Q02318 2 218781749-218815293 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "choroid plexus: 193.4;liver: 575.4" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 185.3;Enterocytes: 225.7;Hepatocytes: 513.1;Oligodendrocytes: 143.8;Retinal pigment epithelial cells: 298.4" "Cell type enhanced" "Detected in many" "Enterocytes: 225.7;Hepatocytes: 513.1;Pigment cells: 298.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 168.2;oligodendrocyte: 201.3" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 337.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 151.6;neutrophil: 126.9" "Group enriched" "Detected in many" 21 "granulocytes: 126.9;monocytes: 151.6" "Cancer enhanced" "Detected in many" "liver cancer: 29.9;skin cancer: 65.6" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Liver - Hepatocytes, Lung - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 64424358.8;Hepatocytes: 146371933.7;Proximal tubules: 92158876.1" "Tissue enriched" "Detected in many" "liver: 67693188.8" HPA059155 Enhanced Approved Mitochondria,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" Mitochondria Cytosol "HPA059155: " "unprognostic (2.54e-1)" "potential prognostic favorable (3.65e-4)" "unprognostic (3.02e-2)" "unprognostic (2.21e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-2)" "validated prognostic unfavorable (5.59e-4)" "validated prognostic unfavorable (2.23e-7)" "unprognostic (1.83e-2)" "unprognostic (5.43e-3)" "potential prognostic favorable (2.52e-7)" "unprognostic (2.41e-3)" "potential prognostic favorable (7.15e-6)" "validated prognostic favorable (3.28e-5)" "validated prognostic favorable (1.33e-5)" "unprognostic (1.75e-3)" "unprognostic (7.71e-2)" "unprognostic (5.24e-3)" "unprognostic (2.92e-1)" "unprognostic (2.02e-1)" "unprognostic (2.96e-3)" "unprognostic (2.43e-2)" "unprognostic (2.96e-1)" "unprognostic (3.03e-3)" "unprognostic (2.69e-1)" "unprognostic (3.71e-2)" "unprognostic (9.55e-2)" "unprognostic (1.64e-2)" "unprognostic (1.91e-1)" "unprognostic (1.05e-1)" "unprognostic (2.28e-1)" CYP27C1 FLJ16008 ENSG00000186684 "Cytochrome P450 family 27 subfamily C member 1" Q4G0S4 2 127183832-127220313 "Enzymes, Predicted intracellular proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 4.8" "Cell type enhanced" "Detected in some" "Breast lactating cells: 34.1;Decidual stromal cells: 13.2;Endometrial stromal cells: 12.5;Esophageal apical cells: 9.5;Fibro-adipogenic progenitors: 11.8;Hepatic stellate cells: 12.9;Leydig cells: 13.3;Ocular epithelial cells: 19.5;Papillary tip epithelial cells: 14.2;Prostatic hillock cells: 15.5;Schwann cells: 41.5;Suprabasal keratinocytes: 13.6;Urothelial cells: 16.3" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 19.5;Glial cells: 41.5;Secretory cells: 34.1" "Cell type enriched" "Detected in many" 6 "thalamic excitatory: 43.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" "HPA062460, HPA068731" Enhanced Vesicles NA NA "Cluster 58: Skin - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" Vesicles "HPA062460: , HPA068731: " "unprognostic (1.36e-1)" "unprognostic (3.52e-1)" "unprognostic (2.71e-1)" "unprognostic (4.74e-2)" "unprognostic (1.15e-3)" "unprognostic (5.03e-2)" "unprognostic (6.38e-3)" "unprognostic (1.61e-2)" "unprognostic (7.34e-3)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "validated prognostic unfavorable (8.31e-4)" "validated prognostic unfavorable (4.03e-6)" "unprognostic (1.67e-2)" "unprognostic (1.23e-2)" "unprognostic (1.49e-1)" CYP2D6 "CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, P450-DB1, P450C2D" ENSG00000100197 "Cytochrome P450 family 2 subfamily D member 6" P10635 22 42126499-42130865 "Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Fatty acid metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "liver: 386.2" "Group enriched" "Detected in some" 13 "Enterocytes: 212.7;Hepatocytes: 109.4" "Group enriched" "Detected in some" 13 "Enterocytes: 212.7;Hepatocytes: 109.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 159 "Liver Hepatocellular Carcinoma (TCGA): 47.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 2256700 "Hepatocytes: 225669985.9" "Tissue enriched" "Detected in single" 1236124 "liver: 123612393.7" HPA045223 Enhanced Approved "Golgi apparatus" No No "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" "Golgi apparatus" "HPA045223: " "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (3.21e-2)" "unprognostic (1.61e-2)" CYP2E1 CYP2E ENSG00000130649 "Cytochrome P450 family 2 subfamily E member 1" P05181 10 133520406-133561220 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 307 "liver: 9697.0" "Cell type enriched" "Detected in many" 45 "Hepatocytes: 7806.9" "Cell type enriched" "Detected in many" 45 "Hepatocytes: 7806.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 292 "Liver Hepatocellular Carcinoma (TCGA): 1994.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.5;myeloid DC: 6.3" "Group enriched" "Detected in many" 16 "dendritic cells: 6.3;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2129393 "Hepatocytes: 212939335.5" "Tissue enriched" "Detected in some" 1 "liver: 246472283.0" "HPA009128, HPA029564" Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 93: Hepatocytes - Bile production & excretion" 2 "Endoplasmic reticulum, Mitochondria" "HPA009128: , HPA029564: " "unprognostic (1.62e-2)" "unprognostic (2.74e-1)" "unprognostic (5.20e-3)" "unprognostic (4.68e-3)" "unprognostic (5.63e-2)" "unprognostic (6.26e-3)" "unprognostic (1.75e-2)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (2.08e-4)" "unprognostic (7.13e-2)" "unprognostic (2.33e-1)" "unprognostic (1.44e-3)" "unprognostic (1.27e-1)" "unprognostic (1.39e-2)" "unprognostic (9.72e-3)" "unprognostic (9.52e-2)" "unprognostic (2.03e-1)" "unprognostic (6.17e-2)" "unprognostic (7.86e-2)" "unprognostic (1.82e-1)" "unprognostic (5.52e-3)" "unprognostic (2.76e-2)" "unprognostic (1.22e-1)" "unprognostic (3.99e-2)" "unprognostic (1.05e-1)" "unprognostic (9.87e-2)" "unprognostic (3.77e-1)" "unprognostic (1.43e-1)" CYP2S1 ENSG00000167600 "Cytochrome P450 family 2 subfamily S member 1" Q96SQ9 19 41193210-41207539 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" "Isomerase, Lyase, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 95.3;stomach 1: 113.5" "Cell type enhanced" "Detected in many" "cDC: 61.0;Colonocytes: 26.8;Cytotrophoblasts: 31.1;Enterocytes: 58.4;Foveolar cells: 232.1;Goblet cells: 40.1;Paneth cells: 30.9;Respiratory basal cells: 45.9;Respiratory deuterosomal cells: 29.0" "Cell type enhanced" "Detected in many" "dendritic cells: 61.0;Enterocytes: 58.4;Gastric glandular cells: 232.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.7;lower rhombic lip: 3.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "classical monocyte: 24.8;myeloid DC: 84.5" "Group enriched" "Detected in many" 131 "dendritic cells: 84.5;monocytes: 24.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Mesothelial cells, Heart muscle - Macrophages, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 3117178.9;Fallopian tube cells: 2969198.3" "Tissue enhanced" "Detected in many" "intestine: 7072440.4" "HPA049227, HPA069248" Approved Supported "Endoplasmic reticulum" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 77: Intestine - Digestion" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 2 "Endoplasmic reticulum" "HPA049227: , HPA069248: " "unprognostic (8.38e-2)" "unprognostic (8.59e-2)" "unprognostic (6.45e-2)" "unprognostic (1.89e-1)" "unprognostic (2.74e-2)" "unprognostic (1.53e-1)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (7.30e-4)" "unprognostic (4.92e-2)" "unprognostic (6.13e-2)" "unprognostic (3.18e-1)" "unprognostic (6.71e-3)" "unprognostic (7.90e-3)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.71e-2)" "unprognostic (7.36e-3)" "unprognostic (2.85e-2)" "unprognostic (1.70e-2)" "unprognostic (1.49e-1)" "unprognostic (7.61e-3)" "unprognostic (8.07e-3)" "unprognostic (1.41e-1)" "unprognostic (1.50e-3)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.37e-1)" "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" "unprognostic (1.52e-2)" CYP51A1 "CP51, CYP51, CYPL1, LDM, P450-14DM, P450L1" ENSG00000001630 "Cytochrome P450 family 51 subfamily A member 1" Q16850 7 92084987-92134803 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" "Monooxygenase, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 188.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 322.6;Early spermatids: 159.9;Epicardial cells: 282.0;Late spermatids: 142.7;Myonuclei: 80.3" "Group enriched" "Detected in many" 4 "Barrier epithelial cells: 282.0;Myocytes: 322.6;Spermatogenic cell types: 159.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 28171853.7" "Tissue enhanced" "Detected in many" "liver: 15086214.4" "HPA041325, HPA043508" Approved Approved "Endoplasmic reticulum" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 14 "Endoplasmic reticulum" "HPA041325: , HPA043508: " "unprognostic (4.11e-2)" "unprognostic (1.18e-1)" "unprognostic (6.94e-2)" "potential prognostic unfavorable (3.28e-5)" "unprognostic (2.94e-3)" "unprognostic (1.37e-1)" "unprognostic (1.32e-1)" "unprognostic (1.64e-3)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (7.26e-4)" "potential prognostic favorable (5.89e-9)" "unprognostic (8.45e-2)" "unprognostic (3.05e-1)" "unprognostic (7.08e-2)" "unprognostic (2.72e-2)" "unprognostic (5.01e-2)" "unprognostic (2.60e-1)" "unprognostic (2.30e-1)" "unprognostic (2.67e-2)" "unprognostic (2.18e-1)" "unprognostic (1.24e-1)" "unprognostic (1.52e-1)" "unprognostic (2.95e-1)" "unprognostic (4.34e-2)" "unprognostic (1.56e-1)" "unprognostic (8.78e-2)" "unprognostic (1.78e-1)" "unprognostic (1.04e-1)" "unprognostic (4.28e-1)" "unprognostic (4.86e-2)" "unprognostic (7.71e-2)" CYSRT1 "C9orf169, MGC59937" ENSG00000197191 "Cysteine rich tail 1" A8MQ03 9 137225174-137226315 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "esophagus: 460.4" "Cell type enriched" "Detected in some" 13 "Esophageal apical cells: 18747.8" "Cell type enriched" "Detected in many" 13 "Apical squamous epithelial cells: 18747.8" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 61.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.0" "Lineage enriched" "Detected in single" 6 "monocytes: 1.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 12550 "Keratinocytes: 1254965.8" "Not detected" "Not detected" "HPA021883, HPA021886" Approved Approved "Nuclear speckles,Vesicles,Midbody" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 398 "Nuclear speckles" "Vesicles, Midbody" "HPA021883: , HPA021886: " "unprognostic (2.04e-1)" "unprognostic (8.58e-2)" "unprognostic (2.99e-2)" "unprognostic (2.17e-2)" "unprognostic (8.36e-2)" "unprognostic (1.20e-1)" "unprognostic (5.79e-2)" "unprognostic (1.73e-2)" "unprognostic (2.19e-2)" "unprognostic (1.66e-2)" "unprognostic (4.93e-2)" "unprognostic (1.76e-3)" "unprognostic (1.52e-1)" "unprognostic (5.14e-2)" "unprognostic (3.63e-1)" "unprognostic (1.28e-1)" "unprognostic (2.17e-1)" "unprognostic (2.03e-1)" "unprognostic (1.30e-3)" "unprognostic (5.64e-1)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "unprognostic (8.59e-2)" "unprognostic (9.49e-2)" "unprognostic (2.33e-1)" "unprognostic (2.65e-1)" "unprognostic (3.12e-2)" CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 55.0;lymphoid tissue: 63.5" "Cell type enhanced" "Detected in some" "cDC: 94.7;Hofbauer cells: 144.4;Kupffer cells: 85.1;Macrophages: 102.3;Mast cells: 54.4;Microglia: 116.3;monocytes: 86.0;Neutrophils: 336.9;NK-cells: 50.7;pDCs: 165.9;Plasma cells: 42.7;T-cells: 44.2" "Cell type enhanced" "Detected in many" "dendritic cells: 165.9;Glial cells: 116.3;Mononuclear phagocytes: 144.4;Neutrophils: 336.9" "Group enriched" "Detected in some" 70 "central nervous system macrophage: 144.5;leukocyte: 75.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 13 "Leukemia: 24.3;lymphoma: 25.1;Myeloma: 12.2" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Macrophages: 8840420.2;T-cells: 4113136.4" "Tissue enriched" "Detected in single" 21696 "lymphoid tissue: 2169593.8" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 24: Neutrophils - Innate immunity signal integration" 21 "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: " "unprognostic (1.26e-2)" "unprognostic (2.20e-2)" "unprognostic (3.74e-3)" "unprognostic (8.09e-2)" "unprognostic (8.00e-2)" "unprognostic (8.95e-2)" "unprognostic (1.33e-2)" "unprognostic (1.33e-1)" "unprognostic (1.17e-2)" "unprognostic (2.13e-1)" "unprognostic (4.69e-2)" "unprognostic (2.47e-1)" "unprognostic (3.48e-1)" "unprognostic (3.33e-2)" "unprognostic (8.04e-2)" "unprognostic (8.39e-3)" "unprognostic (2.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.45e-1)" "unprognostic (3.22e-2)" "unprognostic (2.80e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (8.15e-5)" "unprognostic (2.29e-1)" "unprognostic (1.96e-2)" "unprognostic (8.07e-2)" "unprognostic (4.44e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-2)" "unprognostic (2.09e-2)" "unprognostic (4.03e-2)" CYTIP "B3-1, CASP, CYBR, CYTHIP, HE, PSCDBP" ENSG00000115165 "Cytohesin 1 interacting protein" O60759 2 157414619-157488961 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 99.7;lymphoid tissue: 107.1" "Cell type enhanced" "Detected in many" "B-cells: 394.7;Breast lactating cells: 657.5;cDC: 492.5;Innate lymphoid cells: 267.7;monocytes: 353.9;Neutrophils: 1793.3;NK-cells: 459.5;Plasma cells: 515.3;T-cells: 578.5" "Cell type enhanced" "Detected in many" "dendritic cells: 492.5;Neutrophils: 1793.3;NK-cells: 459.5;Plasma cells: 515.3;Secretory cells: 657.5;T-cells: 578.5" "Cell type enriched" "Detected in some" 8 "leukocyte: 464.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "lymphoma: 87.8;Myeloma: 106.5" "Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Minor Salivary Gland - Plasma cells, Prostate - T-cells, Skin - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "T-cells: 1487216.3" "Tissue enriched" "Detected in single" 1861 "lymphoid tissue: 186099.0" HPA007191 Approved Supported Nucleoplasm,Cytosol No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 Cytosol Nucleoplasm "HPA007191: " "unprognostic (3.98e-2)" "unprognostic (1.01e-3)" "unprognostic (5.22e-3)" "unprognostic (1.32e-3)" "unprognostic (1.21e-1)" "unprognostic (9.59e-2)" "unprognostic (2.69e-3)" "unprognostic (1.17e-2)" "unprognostic (2.30e-3)" "unprognostic (1.05e-1)" "unprognostic (6.26e-2)" "unprognostic (1.04e-1)" "unprognostic (2.26e-2)" "unprognostic (1.14e-1)" "unprognostic (1.39e-1)" "unprognostic (4.74e-3)" "unprognostic (1.46e-1)" "unprognostic (4.34e-2)" "unprognostic (2.10e-1)" "unprognostic (8.44e-2)" "unprognostic (7.91e-2)" "unprognostic (3.39e-2)" "unprognostic (5.10e-2)" "unprognostic (2.37e-1)" "unprognostic (6.91e-2)" "unprognostic (5.31e-2)" "unprognostic (7.68e-3)" "unprognostic (2.70e-1)" "unprognostic (4.76e-2)" "unprognostic (1.91e-1)" "unprognostic (4.65e-2)" CZIB "C1orf123, FLJ20580" ENSG00000162384 "CXXC motif containing zinc binding protein" Q9NWV4 1 53214099-53220634 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 167.1;Late primary spermatocytes: 167.3;Late spermatids: 390.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 390.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA043835 Uncertain Approved "Vesicles,Mitotic spindle,Cytosol" Yes No 690000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 Cytosol "Vesicles, Mitotic spindle" "HPA043835: " "unprognostic (1.56e-2)" "unprognostic (2.87e-1)" "unprognostic (1.92e-1)" "unprognostic (1.50e-1)" "unprognostic (7.51e-2)" "unprognostic (3.08e-1)" "unprognostic (1.59e-3)" "unprognostic (1.73e-3)" "unprognostic (1.93e-1)" "potential prognostic favorable (6.72e-4)" "unprognostic (5.75e-3)" "unprognostic (1.16e-1)" "unprognostic (3.47e-3)" "unprognostic (8.71e-2)" "unprognostic (6.12e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-2)" "unprognostic (6.40e-2)" "unprognostic (1.32e-1)" "unprognostic (2.09e-2)" "unprognostic (2.14e-1)" "unprognostic (2.43e-1)" "unprognostic (7.21e-2)" "unprognostic (1.49e-1)" "unprognostic (6.94e-2)" "unprognostic (4.64e-3)" "unprognostic (2.69e-1)" "unprognostic (1.85e-1)" "unprognostic (2.55e-1)" D2HGDH "D2HGD, FLJ42195, MGC25181" ENSG00000180902 "D-2-hydroxyglutarate dehydrogenase" Q8N465 2 241734602-241768816 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 180.8" "Cell type enhanced" "Detected in all" "Renal nephron cells: 180.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.5" "Group enriched" "Detected in many" 4 "B-cells: 2.5;T-cells: 1.0" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Proximal tubules: 62286791.1" "Low tissue specificity" "Detected in many" "HPA056216, HPA060548" Uncertain Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 88: Proximal tubular cells - Transmembrane transport" 70 Mitochondria "HPA056216: , HPA060548: " "unprognostic (3.13e-1)" "unprognostic (9.72e-2)" "unprognostic (3.17e-2)" "unprognostic (3.03e-2)" "unprognostic (2.48e-1)" "unprognostic (1.33e-1)" "unprognostic (5.89e-2)" "unprognostic (1.72e-1)" "unprognostic (8.98e-3)" "unprognostic (3.08e-2)" "potential prognostic favorable (7.31e-5)" "unprognostic (9.82e-3)" "unprognostic (1.30e-2)" "unprognostic (3.48e-1)" "unprognostic (3.78e-3)" "unprognostic (4.55e-2)" "unprognostic (1.03e-1)" "unprognostic (2.80e-1)" "unprognostic (1.12e-2)" "unprognostic (3.48e-2)" "unprognostic (7.99e-2)" "unprognostic (2.26e-1)" "unprognostic (4.78e-2)" "unprognostic (6.32e-2)" "unprognostic (2.55e-2)" "unprognostic (2.37e-1)" "unprognostic (1.13e-2)" "unprognostic (3.08e-2)" "unprognostic (6.23e-2)" "unprognostic (3.49e-1)" "unprognostic (2.13e-2)" DACH1 DACH ENSG00000276644 "Dachshund family transcription factor 1" Q9UI36 13 71437966-71867204 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 19.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 849.9;Distal convoluted tubule cells: 1034.1;Gonadotrophs: 783.7;Müller glia: 1078.8;Neutrophil progenitors: 1979.1;Neutrophils: 955.5;Paneth cells: 858.6;Podocytes: 5507.1;Renal connecting tubule cells: 750.7;Retinal horizontal cells: 753.3" "Cell type enhanced" "Detected in many" "Neutrophils: 1979.1;Renal nephron cells: 5507.1" "Cell type enhanced" "Detected in all" "endothelial cell: 827.9;medium spiny neuron: 810.4;pericyte: 1190.8" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 15.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 6.0;eosinophil: 11.3;NK-cell: 5.7;plasmacytoid DC: 9.3" "Group enriched" "Detected in many" 29 "dendritic cells: 9.3;granulocytes: 11.3;NK-cells: 5.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 10.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Pituitary gland - Thyrotropes, Skin - Outer root sheath cells, Spleen - Endothelial cells, Testis - Early spermatids" "Region enriched" "Detected in all" 5 "basal ganglia: 38.8" "Region enriched" "Detected in all" 6 "basal ganglia: 45.2" "Group enriched" "Detected in some" "Distal tubules: 1205802.0;Glomeruli: 562980.5;Neutrophils: 363390.8;Proximal tubules: 760659.6" "Group enriched" "Detected in some" 13863 "fallopian tube: 1154272.2;lung: 1310735.1;lymphoid tissue: 1458611.5;ovary: 1621565.6" "HPA012672, HPA012938, HPA073222" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 42: Retina - Visual perception" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" 12 "Nucleoplasm, Nuclear speckles" "HPA012672: , HPA012938: , HPA073222: " "unprognostic (1.31e-1)" "unprognostic (2.38e-1)" "unprognostic (4.50e-2)" "unprognostic (8.11e-2)" "unprognostic (2.45e-1)" "unprognostic (4.54e-2)" "unprognostic (2.61e-2)" "unprognostic (1.26e-1)" "validated prognostic favorable (2.89e-4)" "validated prognostic favorable (6.01e-4)" "unprognostic (9.68e-2)" "unprognostic (1.27e-2)" "unprognostic (1.96e-1)" "unprognostic (2.19e-1)" "unprognostic (2.11e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (4.13e-4)" "unprognostic (3.40e-1)" "unprognostic (2.22e-1)" "unprognostic (2.87e-3)" "unprognostic (1.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.46e-3)" DAGLB "DAGLBETA, KCCR13L" ENSG00000164535 "Diacylglycerol lipase beta" Q8NCG7 7 6409126-6484190 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 71.3;Microglia: 97.6;Neutrophil progenitors: 78.3" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 118.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 88.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 4639591.3;Neutrophils: 12716785.6" "Low tissue specificity" "Detected in many" HPA069377 Supported "Nucleoplasm,Plasma membrane" No No "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 "Plasma membrane" Nucleoplasm "HPA069377: " "unprognostic (3.75e-1)" "unprognostic (1.27e-2)" "unprognostic (2.33e-1)" "unprognostic (1.39e-2)" "unprognostic (1.62e-1)" "unprognostic (2.36e-1)" "unprognostic (2.06e-2)" "unprognostic (1.05e-1)" "unprognostic (2.89e-2)" "unprognostic (5.54e-3)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.46e-1)" "unprognostic (5.02e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (1.85e-1)" "unprognostic (9.90e-2)" "unprognostic (1.78e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (6.40e-3)" "unprognostic (1.24e-2)" "unprognostic (1.98e-1)" "unprognostic (4.34e-3)" "unprognostic (8.67e-2)" "unprognostic (1.21e-1)" "unprognostic (5.59e-2)" "unprognostic (1.12e-1)" "unprognostic (1.49e-1)" "unprognostic (2.01e-1)" "unprognostic (2.09e-2)" "unprognostic (2.16e-1)" DAPK1 DAPK ENSG00000196730 "Death associated protein kinase 1" P53355 9 87497228-87708634 "Cancer-related genes, Enzymes, Human disease related genes, Predicted membrane proteins" "Apoptosis, Translation regulation" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 707.3;Hematopoietic stem cells: 614.8;Mesothelial cells: 809.7;Renal collecting duct principal cells: 550.9;Transitional alveolar cells: 532.5" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 809.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 6.7;eosinophil: 8.7;intermediate monocyte: 14.0;myeloid DC: 4.8;non-classical monocyte: 15.3;plasmacytoid DC: 6.2" "Group enriched" "Detected in many" 56 "dendritic cells: 6.2;granulocytes: 8.7;monocytes: 15.3" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Skeletal muscle - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 1966966.5;Hepatocytes: 4590625.6" "Tissue enriched" "Detected in some" "ovary: 13809219.3" "HPA003516, CAB037302, HPA040472, HPA048436" Approved Approved Centrosome NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 45 Centrosome "CAB037302: , HPA003516: , HPA040472: , HPA048436: " "unprognostic (1.67e-3)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (9.84e-3)" "unprognostic (5.11e-3)" "unprognostic (2.55e-1)" "unprognostic (1.12e-3)" "unprognostic (1.17e-1)" "unprognostic (3.40e-3)" "potential prognostic favorable (5.29e-6)" "unprognostic (4.55e-3)" "unprognostic (3.96e-1)" "unprognostic (6.60e-2)" "unprognostic (2.00e-1)" "unprognostic (9.92e-2)" "unprognostic (7.40e-2)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (7.49e-3)" "unprognostic (6.50e-2)" "unprognostic (1.85e-2)" "unprognostic (2.72e-1)" "unprognostic (4.49e-3)" "unprognostic (1.10e-2)" "unprognostic (9.13e-2)" "unprognostic (1.09e-3)" "unprognostic (5.14e-2)" "unprognostic (5.38e-1)" "unprognostic (1.72e-1)" "unprognostic (3.60e-2)" DAPK3 "ZIP, ZIPK" ENSG00000167657 "Death associated protein kinase 3" O43293 19 3958453-3971123 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation, Translation regulation" "Activator, Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 168.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 23111948.5" "Group enriched" "Detected in many" "blood vessel: 5078833.4;heart muscle: 4703559.5;intestine: 2270434.5" HPA028569 Approved Supported "Nucleoplasm,Vesicles,Primary cilium,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 15 "Nucleoplasm, Cytosol" "Vesicles, Primary cilium" "HPA028569: " "unprognostic (8.38e-2)" "unprognostic (5.74e-2)" "unprognostic (8.91e-2)" "unprognostic (1.08e-2)" "unprognostic (3.35e-1)" "unprognostic (9.85e-2)" "unprognostic (2.49e-1)" "unprognostic (3.08e-1)" "unprognostic (4.19e-1)" "unprognostic (1.78e-2)" "unprognostic (1.75e-3)" "unprognostic (9.76e-2)" "unprognostic (2.38e-2)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.13e-1)" "unprognostic (5.75e-2)" "unprognostic (2.26e-1)" "unprognostic (1.34e-1)" "unprognostic (2.91e-1)" "unprognostic (3.96e-1)" "unprognostic (1.13e-1)" "unprognostic (1.50e-1)" "unprognostic (1.38e-1)" "unprognostic (1.45e-1)" "unprognostic (5.36e-3)" "unprognostic (1.54e-2)" "unprognostic (1.39e-1)" "unprognostic (1.94e-1)" "unprognostic (2.67e-2)" "unprognostic (6.54e-2)" DAZAP1 MGC19907 ENSG00000071626 "DAZ associated protein 1" Q96EP5 19 1407569-1435687 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA004201, HPA004631" Enhanced Supported Nucleoplasm,Midbody,Cytosol Yes NA 83000 "Cluster 13: Non-specific - Mitochondria" "Cluster 47: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 17 Nucleoplasm "Midbody, Cytosol" "HPA004201: , HPA004631: " "unprognostic (1.29e-1)" "unprognostic (1.69e-1)" "unprognostic (1.68e-1)" "unprognostic (4.16e-2)" "unprognostic (1.18e-2)" "unprognostic (3.53e-1)" "unprognostic (1.35e-2)" "unprognostic (8.09e-3)" "unprognostic (1.33e-2)" "unprognostic (7.09e-3)" "unprognostic (2.27e-1)" "unprognostic (5.17e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.46e-5)" "unprognostic (1.34e-3)" "unprognostic (2.08e-2)" "unprognostic (2.90e-3)" "unprognostic (4.13e-1)" "unprognostic (1.37e-2)" "unprognostic (2.57e-1)" "unprognostic (9.72e-3)" "unprognostic (1.69e-1)" "unprognostic (1.24e-2)" "unprognostic (1.35e-2)" "unprognostic (8.73e-3)" "potential prognostic favorable (2.19e-4)" "unprognostic (6.46e-2)" "unprognostic (1.43e-2)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (2.17e-3)" DBF4 "ASK, chif, DBF4A, ZDBF1" ENSG00000006634 "DBF4 zinc finger" Q9UBU7 7 87876216-87909553 "Essential proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "testis: 14.2" "Group enriched" "Detected in many" 4 "Early spermatids: 314.8;Late primary spermatocytes: 1165.2" "Cell type enriched" "Detected in all" 11 "Spermatogenic cell types: 1165.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 575 "Neutrophils: 57540.7" "Not detected" "Not detected" HPA042923 Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 15 "Nucleoplasm, Nuclear bodies" "HPA042923: " "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (1.99e-2)" "unprognostic (3.30e-3)" "unprognostic (6.66e-3)" "potential prognostic unfavorable (5.43e-5)" "unprognostic (2.03e-1)" "unprognostic (8.53e-3)" "unprognostic (9.63e-2)" DBF4B "ASKL1, chifb, DRF1, FLJ13087, ZDBF1B" ENSG00000161692 "DBF4 zinc finger B" Q8NFT6 17 44708608-44752264 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 90.9;Retinal amacrine cells: 45.1" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 90.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048465, HPA077959" Approved Supported Nucleoplasm,Vesicles NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 3 Nucleoplasm Vesicles "HPA048465: , HPA077959: " "unprognostic (1.00e-2)" "unprognostic (2.16e-1)" "unprognostic (2.01e-1)" "unprognostic (1.61e-1)" "unprognostic (1.28e-2)" "unprognostic (8.46e-2)" "unprognostic (7.75e-3)" "unprognostic (3.45e-2)" "unprognostic (6.93e-2)" "unprognostic (1.11e-3)" "unprognostic (5.14e-2)" "unprognostic (1.80e-2)" "unprognostic (1.16e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (1.25e-1)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (5.38e-2)" "unprognostic (4.85e-3)" "unprognostic (4.13e-2)" "unprognostic (5.59e-2)" "unprognostic (4.28e-1)" "unprognostic (2.09e-1)" "unprognostic (8.22e-2)" DBH DBM ENSG00000123454 "Dopamine beta-hydroxylase" P09172 9 133636363-133659329 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "adrenal gland: 257.4" "Cell type enriched" "Detected in some" 9 "Adrenal medulla cells: 893.5" "Cell type enriched" "Detected in some" 9 "Adrenal endocrine cells: 893.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 2.5" "Region enriched" "Detected in many" 22 "pons: 513.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 24 "Neuroblastoma: 209.4" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes" "Region enriched" "Detected in some" 6 "pons and medulla: 22.1" "Region enriched" "Detected in single" 26 "pons: 22.1" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1745692.2;Capillaries: 1039759.8" "Tissue enhanced" "Detected in many" "intestine: 4223748.0" "HPA002130, HPA005960, HPA070789" Enhanced Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme NA NA 520000000 "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 18: Adrenal cortex cells - Steroidogensis" 18 Vesicles "Endoplasmic reticulum" "HPA002130: , HPA005960: , HPA070789: " "unprognostic (1.28e-2)" "unprognostic (7.34e-3)" "potential prognostic favorable (1.86e-5)" "unprognostic (1.57e-1)" DBNDD1 "FLJ12582, MGC3101" ENSG00000003249 "Dysbindin domain containing 1" Q9H9R9 16 90004871-90019890 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 91.5;skeletal muscle: 46.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 23.4;Cardiomyocytes: 45.9;Cholangiocytes: 31.5;Epicardial cells: 18.2;Esophageal apical cells: 69.3;Esophageal suprabasal cells: 36.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 69.3;Myocytes: 45.9;Suprabasal cells: 36.8" "Cell type enhanced" "Detected in many" "thalamic excitatory: 26.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "naive B-cell: 12.9" "Lineage enriched" "Detected in many" 4 "B-cells: 12.9" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 21720 "cerebral cortex: 2172044.9" HPA043018 Uncertain Approved "Nuclear speckles,Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" No No "Cluster 34: B-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 1 "Nuclear speckles" "Cytosol, Equatorial segment, Mid piece, Principal piece, End piece" "HPA043018: " "unprognostic (7.83e-2)" "unprognostic (6.26e-2)" "unprognostic (4.39e-2)" "unprognostic (1.70e-2)" "unprognostic (2.35e-1)" "unprognostic (1.47e-2)" "unprognostic (7.20e-2)" "unprognostic (9.89e-3)" "unprognostic (1.40e-1)" "unprognostic (9.63e-3)" "unprognostic (1.91e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (1.56e-1)" "unprognostic (5.16e-2)" "unprognostic (1.55e-1)" "unprognostic (6.52e-2)" "unprognostic (1.54e-1)" "unprognostic (4.37e-1)" "unprognostic (1.34e-1)" "unprognostic (2.41e-1)" "unprognostic (1.15e-1)" "unprognostic (3.30e-1)" "unprognostic (3.25e-2)" "unprognostic (3.06e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" "unprognostic (8.23e-2)" "unprognostic (3.60e-1)" "unprognostic (1.66e-1)" "unprognostic (1.37e-1)" DBR1 ENSG00000138231 "Debranching RNA lariats 1" Q9UK59 3 138160988-138174949 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "mRNA processing" Hydrolase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "skin: 8568070.3" HPA035365 Supported Approved Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 Nucleoplasm "HPA035365: " "unprognostic (2.18e-2)" "unprognostic (1.97e-1)" "unprognostic (2.58e-2)" "unprognostic (2.12e-1)" "unprognostic (1.34e-1)" "unprognostic (5.69e-3)" "unprognostic (3.96e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-1)" "unprognostic (3.69e-2)" "potential prognostic favorable (4.12e-6)" "unprognostic (3.33e-3)" "unprognostic (2.90e-3)" "unprognostic (4.41e-3)" "unprognostic (2.49e-2)" "unprognostic (1.23e-1)" "unprognostic (7.43e-2)" "unprognostic (2.72e-2)" "unprognostic (1.29e-2)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (1.25e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-2)" "unprognostic (2.47e-2)" "unprognostic (7.70e-2)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.64e-1)" "unprognostic (3.32e-1)" "unprognostic (1.37e-1)" DBT "BCKAD-E2, BCKDH-E2, BCOADC-E2" ENSG00000137992 "Dihydrolipoamide branched chain transacylase E2" P11182 1 100186919-100249834 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Maple syrup urine disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Parietal cells: 141.4;Prostatic glandular cells: 104.4" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 141.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 66.5" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubules: 161080934.1" "Low tissue specificity" "Detected in all" "HPA026481, HPA026485, HPA026533" Enhanced Supported Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 41 Mitochondria "HPA026481: , HPA026485: , HPA026533: " "unprognostic (3.47e-3)" "unprognostic (1.72e-2)" "unprognostic (8.60e-2)" "unprognostic (8.11e-2)" "unprognostic (7.39e-3)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (6.64e-3)" "unprognostic (1.06e-1)" "unprognostic (1.10e-1)" "validated prognostic favorable (3.24e-8)" "validated prognostic favorable (3.36e-5)" "unprognostic (6.11e-2)" "unprognostic (1.67e-1)" "unprognostic (7.82e-2)" "unprognostic (4.96e-2)" "unprognostic (4.80e-2)" "unprognostic (2.68e-1)" "unprognostic (2.11e-1)" "unprognostic (4.19e-2)" "unprognostic (9.47e-3)" "unprognostic (2.18e-3)" "unprognostic (3.02e-2)" "unprognostic (2.07e-1)" "unprognostic (1.73e-3)" "unprognostic (6.53e-2)" "unprognostic (3.27e-2)" "unprognostic (4.06e-1)" "unprognostic (3.51e-1)" "unprognostic (9.99e-2)" "unprognostic (6.23e-2)" DCAF1 "KIAA0800, MGC102804, VPRBP" ENSG00000145041 "DDB1 and CUL4 associated factor 1" Q9Y4B6 3 51395867-51500015 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 47.6" "Group enriched" "Detected in many" 4 "Early spermatids: 174.4;Late spermatids: 540.3" "Cell type enriched" "Detected in all" 6 "Spermatogenic cell types: 540.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 9888663.2" "Low tissue specificity" "Detected in many" "HPA036142, HPA052445, HPA053203" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 75 Nucleoplasm "Nucleoli fibrillar center" "HPA036142: , HPA052445: , HPA053203: " "unprognostic (2.87e-2)" "unprognostic (3.55e-1)" "unprognostic (2.79e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (5.54e-2)" "unprognostic (3.28e-1)" "unprognostic (3.05e-2)" "unprognostic (7.87e-2)" "potential prognostic favorable (5.09e-4)" "unprognostic (2.13e-3)" "unprognostic (3.25e-2)" "unprognostic (4.74e-2)" "unprognostic (4.78e-2)" "unprognostic (1.17e-2)" "unprognostic (6.68e-2)" "unprognostic (5.13e-3)" "unprognostic (9.94e-2)" "unprognostic (3.00e-2)" "unprognostic (3.28e-2)" "unprognostic (1.34e-1)" "unprognostic (2.53e-2)" "unprognostic (3.22e-2)" "unprognostic (1.31e-1)" "unprognostic (3.27e-1)" "unprognostic (7.77e-2)" "unprognostic (2.42e-1)" "unprognostic (3.42e-2)" "unprognostic (3.14e-1)" DCAF8 "FLJ35857, H326, WDR42A" ENSG00000132716 "DDB1 and CUL4 associated factor 8" Q5TAQ9 1 160215715-160262549 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 75.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA027218, HPA027381" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 46 Nucleoplasm Cytosol "HPA027218: , HPA027381: " "unprognostic (2.65e-2)" "unprognostic (9.12e-2)" "unprognostic (1.78e-1)" "unprognostic (8.44e-3)" "unprognostic (1.16e-1)" "unprognostic (1.64e-2)" "unprognostic (1.50e-1)" "unprognostic (2.08e-2)" "unprognostic (9.50e-3)" "unprognostic (2.36e-2)" "validated prognostic favorable (4.93e-5)" "validated prognostic favorable (7.22e-5)" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (2.33e-4)" "unprognostic (8.33e-2)" "unprognostic (1.51e-1)" "unprognostic (6.96e-2)" "unprognostic (2.66e-2)" "unprognostic (1.40e-1)" "unprognostic (3.94e-2)" "unprognostic (8.56e-2)" "unprognostic (6.13e-2)" "unprognostic (2.33e-1)" "unprognostic (3.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.47e-1)" "unprognostic (4.15e-2)" "unprognostic (6.09e-2)" DCC "IGDCC1, NTN1R1" ENSG00000187323 "DCC netrin 1 receptor" P43146 18 52340197-53535903 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0;testis: 7.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 744.0;Brain inhibitory neurons: 1141.3;Corticotrophs: 2012.7;Early spermatids: 414.9;Late spermatids: 291.7;Oligodendrocyte progenitor cells: 1894.5;Other brain neurons: 646.5;Plasma cells: 382.2;Retinal amacrine cells: 543.0;Thyrotrophs: 568.4" "Group enriched" "Detected in many" 4 "Glial cells: 1894.5;Neuronal cells: 1141.3;Pituitary endocrine cells: 2012.7" "Cell type enhanced" "Detected in all" "hippocampal CA4: 3187.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.1;Lung Squamous Cell Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bone cancer: 6.9;Myeloma: 23.2" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Plasma cells, Spleen - Plasma cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Plasma cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 1427194.8;Microglia and Neuropil: 1657022.7;Oocytes: 828359.7" "Tissue enriched" "Detected in some" "liver: 1871289.7" "HPA055376, HPA069552" Enhanced Approved "Golgi apparatus,Centriolar satellite,Centrosome,Basal body" NA NA 35000 "Cluster 67: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 39 "Golgi apparatus" "Centriolar satellite, Centrosome, Basal body" "HPA055376: , HPA069552: " "unprognostic (5.96e-3)" "unprognostic (4.28e-2)" "unprognostic (2.76e-1)" "unprognostic (4.47e-3)" DCDC2 "DCDC2A, DFNB66, KIAA1154, NPHP19, RU2" ENSG00000146038 "Doublecortin domain containing 2" Q9UHG0 6 24171755-24358059 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Neurogenesis" "Ciliopathy, Deafness, Disease variant, Nephronophthisis, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.5;kidney: 20.4;pancreas: 24.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 391.8;Distal convoluted tubule cells: 1047.2;Endometrial ciliated cells: 820.7;Endometrial glandular cells: 606.1;Endometrial luminal cells: 365.8;Ependymal cells: 369.9;Epididymal efferent duct absorptive cells: 796.2;Epididymal efferent duct ciliated cells: 781.1;Loop of henle epithelial cells: 373.0;Pancreatic duct cells: 574.2;Proximal tubule cells: 415.6;Renal collecting duct principal cells: 385.0;Renal connecting tubule cells: 1441.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 820.7;Ductal cells: 1441.3;Glandular cells: 606.1;Renal nephron cells: 1047.2" "Group enriched" "Detected in many" 10 "choroid plexus epithelial cell: 384.7;ependymal cell: 400.5" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 36.9" "Region enriched" "Detected in all" 5 "choroid plexus: 33.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 45.3;ovarian cancer: 38.7" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Pancreas - Ductal cells, Stomach - Parietal cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Collecting ducts: 8509645.8" "Tissue enriched" "Detected in some" "kidney: 1732173.9" "HPA031582, HPA031583, HPA031584" Enhanced Approved "Microtubules,Mitotic spindle,Centriolar satellite,Cytosol,Acrosome,Equatorial segment,Principal piece" Yes NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 26 "Microtubules, Cytosol" "Mitotic spindle, Centriolar satellite, Acrosome, Equatorial segment, Principal piece" "HPA031582: , HPA031583: , HPA031584: " "unprognostic (1.27e-2)" "unprognostic (2.85e-2)" "unprognostic (2.43e-2)" "unprognostic (2.93e-2)" "unprognostic (5.12e-1)" "unprognostic (1.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.36e-3)" "unprognostic (2.04e-2)" "unprognostic (2.93e-3)" "unprognostic (9.69e-3)" "unprognostic (1.03e-1)" "unprognostic (8.42e-2)" "unprognostic (2.33e-1)" "unprognostic (2.05e-3)" "unprognostic (1.45e-1)" "unprognostic (5.55e-2)" "unprognostic (7.25e-2)" "unprognostic (1.49e-1)" "unprognostic (6.88e-2)" "unprognostic (5.39e-2)" "unprognostic (3.71e-1)" "unprognostic (2.19e-1)" "unprognostic (3.63e-2)" "unprognostic (5.90e-2)" "unprognostic (1.53e-1)" "unprognostic (2.12e-1)" DCST1 FLJ32785 ENSG00000163357 "DC-STAMP domain containing 1" Q5T197 1 155033824-155050930 "Enzymes, Predicted membrane proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 2.4;skin 1: 2.9;testis: 6.3" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 49.7;Early spermatids: 32.0;Late primary spermatocytes: 50.8;Late spermatids: 28.6;Paneth cells: 15.5;Rod photoreceptor cells: 46.3" "Group enriched" "Detected in many" 6 "Neuronal cells: 49.7;Secretory gland support: 15.5;Spermatogenic cell types: 50.8" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 223978 "heart muscle: 22397819.3" HPA060314 Uncertain Approved "Acrosome,Equatorial segment,Principal piece" NA NA "Cluster 47: Testis - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Principal piece" "Acrosome, Equatorial segment" "HPA060314: " "unprognostic (1.33e-1)" DCT "TRP-2, TRP2, TYRP2" ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Melanin biosynthesis" Isomerase "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 101.6" "Cell type enriched" "Detected in many" 90 "Melanocytes: 9101.9" "Cell type enriched" "Detected in many" 90 "Pigment cells: 9101.9" "Cell type enriched" "Detected in many" 9 "committed oligodendrocyte precursor: 152.3" "Cancer enriched" "Detected in some" 203 "Skin Cutaneous Melanoma (TCGA): 338.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 26 "skin cancer: 361.4" "Liver - Hepatocytes, Skin - Melanocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: Skin - Keratinization" "Cluster 33: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 7 "Plasma membrane" Vesicles "CAB017634: , HPA010742: , HPA010743: , HPA010800: " "unprognostic (3.25e-2)" "unprognostic (4.05e-3)" "unprognostic (1.94e-2)" DCTN1 ENSG00000204843 "Dynactin subunit 1" Q14203 2 74361154-74392087 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transport" "Amyotrophic lateral sclerosis, Cancer-related genes, Neurodegeneration, Neuropathy, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Other brain neurons: 45.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB009108, HPA034635, HPA069977, HPA071875" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Acrosome,Perinuclear theca" Yes No 170000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 98: Neurons - Neurotransmission & signaling" 168 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body, Acrosome, Perinuclear theca" "CAB009108: , HPA034635: , HPA069977: , HPA071875: " "unprognostic (2.93e-1)" "unprognostic (1.64e-1)" "unprognostic (4.44e-2)" "unprognostic (1.80e-2)" "unprognostic (8.75e-2)" "unprognostic (1.54e-1)" "unprognostic (2.89e-1)" "potential prognostic favorable (1.61e-4)" "unprognostic (1.51e-1)" "unprognostic (1.89e-1)" "validated prognostic favorable (4.45e-9)" "validated prognostic favorable (7.92e-4)" "unprognostic (3.22e-2)" "unprognostic (1.86e-2)" "unprognostic (3.09e-3)" "unprognostic (4.18e-1)" "unprognostic (1.43e-1)" "unprognostic (6.76e-2)" "unprognostic (3.15e-1)" "unprognostic (4.64e-3)" "unprognostic (3.61e-2)" "unprognostic (1.98e-1)" "unprognostic (5.06e-2)" "unprognostic (1.24e-1)" "unprognostic (5.28e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.37e-1)" "unprognostic (2.41e-1)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" DCTN4 "Dyn4, p62" ENSG00000132912 "Dynactin subunit 4" Q9UJW0 5 150708440-150759095 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 314.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in all" "cerebral cortex: 22627286.2" "CAB017532, HPA038026" Uncertain Approved Nucleoplasm,Centrosome,Calyx NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 48 "Nucleoplasm, Centrosome" Calyx "CAB017532: , HPA038026: " "unprognostic (2.92e-2)" "unprognostic (8.22e-2)" "unprognostic (2.48e-1)" "unprognostic (9.45e-3)" "unprognostic (1.14e-2)" "unprognostic (1.25e-1)" "unprognostic (2.15e-1)" "unprognostic (3.33e-2)" "unprognostic (6.15e-3)" "potential prognostic unfavorable (3.34e-4)" "potential prognostic favorable (2.50e-6)" "unprognostic (1.24e-2)" "unprognostic (2.41e-1)" "unprognostic (4.85e-3)" "unprognostic (2.15e-1)" "unprognostic (9.45e-2)" "unprognostic (2.35e-1)" "unprognostic (2.94e-1)" "unprognostic (4.52e-1)" "unprognostic (9.22e-2)" "unprognostic (7.27e-2)" "unprognostic (2.06e-1)" "unprognostic (1.87e-2)" "unprognostic (2.31e-1)" "unprognostic (4.42e-2)" "unprognostic (6.24e-2)" "unprognostic (3.01e-1)" "unprognostic (5.84e-2)" "unprognostic (4.57e-1)" "unprognostic (1.65e-2)" "unprognostic (3.14e-1)" DCTN5 "MGC3248, p25" ENSG00000166847 "Dynactin subunit 5" Q9BTE1 16 23641466-23677472 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 131.3" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 131.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA042003, HPA063710" Approved Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 37 "Nucleoplasm, Nuclear membrane" "HPA042003: , HPA063710: " "unprognostic (4.06e-2)" "unprognostic (1.73e-2)" "unprognostic (2.11e-1)" "unprognostic (1.48e-1)" "unprognostic (2.65e-1)" "unprognostic (2.12e-1)" "unprognostic (4.10e-1)" "potential prognostic favorable (2.60e-4)" "unprognostic (3.03e-2)" "unprognostic (4.01e-2)" "potential prognostic favorable (7.07e-6)" "unprognostic (9.62e-2)" "unprognostic (3.98e-2)" "unprognostic (4.76e-3)" "unprognostic (6.91e-2)" "unprognostic (4.11e-2)" "unprognostic (1.18e-2)" "unprognostic (1.45e-1)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.47e-3)" "unprognostic (8.86e-3)" "unprognostic (8.70e-3)" "unprognostic (2.70e-1)" "unprognostic (5.88e-2)" "unprognostic (1.61e-1)" "unprognostic (1.07e-1)" "unprognostic (2.34e-2)" "unprognostic (5.02e-2)" "unprognostic (7.64e-2)" "unprognostic (1.08e-1)" DCX "DBCN, DC, LISX, SCLH, XLIS" ENSG00000077279 Doublecortin O43602 X 111293779-111412429 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Epilepsy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;retina: 2.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 32.2;Brain inhibitory neurons: 94.3;Corticotrophs: 21.6;Extravillous trophoblasts: 20.9;Gonadotrophs: 16.3;Oligodendrocyte progenitor cells: 53.5;Other brain neurons: 64.5;Rod photoreceptor cells: 36.7" "Cell type enhanced" "Detected in some" "Glial cells: 53.5;Neuronal cells: 94.3;Pituitary endocrine cells: 21.6;Trophoblast cells: 20.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 9.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Neuroblastoma: 31.0" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Beta cells, Pituitary gland - Thyrotropes, Skin - Fibroblasts_1" "Region enriched" "Detected in many" 9 "olfactory bulb: 74.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 103.8" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 2779914.0;Granulosa cells: 972487.6;Microglia and Neuropil: 1619949.1;Neurons: 2072507.2" "Tissue enriched" "Detected in single" 6812 "cerebral cortex: 681223.2" "HPA036121, HPA059243" Enhanced Supported Enhanced Cytosol NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 21 Cytosol "HPA036121: , HPA059243: " "unprognostic (1.32e-1)" "unprognostic (2.05e-1)" "potential prognostic favorable (2.91e-4)" "unprognostic (1.28e-1)" DDA1 "C19orf58, MGC2594, PCIA1" ENSG00000130311 "DET1 and DDB1 associated 1" Q9BW61 19 17309518-17323298 "Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 151.9;Early spermatids: 473.3;Esophageal apical cells: 245.7;Extravillous trophoblasts: 196.5;Late primary spermatocytes: 293.2;Late spermatids: 158.8;Migrating cytotrophoblasts: 202.1;Syncytiotrophoblasts: 306.4" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 245.7;Spermatogenic cell types: 473.3;Trophoblast cells: 306.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 1029277.2;Keratinocytes: 2434607.5;Neurons: 2515646.5" "Group enriched" "Detected in many" "intestine: 119671331.8;Stomach: 38398948.5" "HPA042134, HPA055272" Approved Approved Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 71 "Nucleoplasm, Nucleoli" "HPA042134: , HPA055272: " "unprognostic (1.71e-2)" "unprognostic (3.32e-1)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (9.34e-3)" "unprognostic (4.56e-2)" "unprognostic (9.02e-2)" "unprognostic (1.27e-1)" "unprognostic (5.01e-3)" "unprognostic (3.43e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.04e-3)" "unprognostic (9.61e-3)" "unprognostic (3.07e-1)" "unprognostic (1.75e-1)" "unprognostic (1.05e-2)" "unprognostic (1.39e-1)" "unprognostic (2.00e-1)" "unprognostic (7.97e-2)" "unprognostic (1.27e-1)" "unprognostic (2.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.18e-1)" "unprognostic (3.94e-1)" "unprognostic (4.37e-2)" "unprognostic (1.70e-1)" "unprognostic (4.27e-2)" "unprognostic (1.40e-1)" DDC AADC ENSG00000132437 "Dopa decarboxylase" P20711 7 50458436-50565405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Catecholamine biosynthesis" "Decarboxylase, Lyase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 156.1;kidney: 294.0;retina: 162.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 63.8;Enterocytes: 32.7;Neuroendocrine cells: 32.9;Proximal tubule cells: 16.3;Retinal bipolar cells: 10.7;Retinal ganglion cells: 11.6;Retinal horizontal cells: 14.0;Rod photoreceptor cells: 108.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 63.8;Enterocytes: 32.7;Enteroendocrine cells: 32.9;Neuronal cells: 108.9" "Cell type enhanced" "Detected in single" "splatter: 1.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 9 "midbrain: 179.5;pons: 59.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 108.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "midbrain: 97.7;pons: 40.1" "Group enriched" "Detected in many" "Glomeruli: 247774790.0;Proximal tubules: 563507020.6" "Group enriched" "Detected in many" "intestine: 38239545.2;kidney: 25826158.2;lymphoid tissue: 25297803.5;ovary: 10522444.5" HPA017742 Enhanced Approved "Actin filaments,Primary cilium" NA NA 130000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Actin filaments" "Primary cilium" "HPA017742: " "unprognostic (2.47e-1)" "unprognostic (1.89e-1)" "unprognostic (3.38e-2)" "unprognostic (1.47e-2)" "potential prognostic favorable (2.83e-8)" "unprognostic (1.73e-3)" "unprognostic (5.61e-2)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (1.71e-5)" "unprognostic (9.25e-2)" "unprognostic (1.47e-1)" "unprognostic (4.93e-3)" "unprognostic (2.96e-2)" "unprognostic (4.48e-2)" "unprognostic (4.61e-3)" "unprognostic (1.85e-2)" "unprognostic (1.67e-2)" "unprognostic (1.02e-3)" "unprognostic (3.45e-1)" "unprognostic (6.25e-2)" "unprognostic (3.79e-1)" "potential prognostic unfavorable (2.27e-4)" DDIT3 "CHOP, CHOP10, GADD153" ENSG00000175197 "DNA damage inducible transcript 3" P35638 12 57516588-57521737 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Growth arrest, Stress response, Transcription, Transcription regulation, Unfolded protein response, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Epididymal principal cells: 3123.3" "Cell type enriched" "Detected in all" 5 "Reproductive supporting cells: 3123.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 291.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 170.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058416, HPA068416" Uncertain Supported Nucleoplasm No No "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 73 Nucleoplasm "HPA058416: , HPA068416: " "unprognostic (1.59e-1)" "unprognostic (6.69e-3)" "unprognostic (1.40e-1)" "unprognostic (2.68e-1)" "unprognostic (1.17e-2)" "unprognostic (2.38e-2)" "unprognostic (1.72e-2)" "unprognostic (9.47e-2)" "unprognostic (4.48e-2)" "unprognostic (3.79e-2)" "potential prognostic unfavorable (9.20e-6)" "unprognostic (6.97e-2)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (7.09e-4)" "unprognostic (1.28e-1)" "unprognostic (3.62e-1)" "unprognostic (7.55e-2)" "unprognostic (1.14e-1)" "unprognostic (2.17e-1)" "unprognostic (2.36e-2)" "unprognostic (1.27e-1)" "unprognostic (6.76e-2)" "unprognostic (7.96e-3)" "unprognostic (9.13e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.90e-5)" "unprognostic (2.69e-1)" "unprognostic (3.31e-1)" "unprognostic (1.46e-1)" "unprognostic (4.63e-2)" DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 304.7;Adrenal cortex cells: 741.1;Choroid plexus epithelial cells: 586.4;Endometrial stromal cells: 184.4;Fibro-adipogenic progenitors: 516.1;Fibroblasts: 366.1;Retinal pigment epithelial cells: 306.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 741.1;Ciliated cells: 586.4;Fibro-adipogenic progenitors: 516.1;Fibroblasts: 366.1" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 472.9;fibroblast: 253.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 44.3" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 143902.1" "Tissue enriched" "Detected in many" "intestine: 722243.7" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 490000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 37 "Plasma membrane, Actin filaments" "HPA070112: " "unprognostic (4.93e-3)" "unprognostic (5.52e-2)" "unprognostic (1.10e-2)" "unprognostic (6.72e-3)" "unprognostic (5.10e-2)" "unprognostic (1.04e-1)" "unprognostic (6.48e-2)" "unprognostic (3.25e-2)" "unprognostic (1.76e-1)" "unprognostic (1.71e-1)" "unprognostic (4.29e-3)" "unprognostic (5.27e-2)" "potential prognostic unfavorable (5.22e-7)" "unprognostic (2.74e-1)" "unprognostic (3.36e-2)" "unprognostic (1.89e-2)" "unprognostic (8.95e-2)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (5.31e-3)" "potential prognostic unfavorable (9.83e-6)" "unprognostic (1.68e-1)" "unprognostic (4.52e-2)" "unprognostic (1.59e-1)" "unprognostic (5.70e-2)" "unprognostic (1.48e-2)" "unprognostic (6.21e-2)" "unprognostic (3.94e-3)" "unprognostic (6.62e-2)" "unprognostic (3.10e-2)" "unprognostic (1.49e-1)" DDX1 DBP-RB ENSG00000079785 "DEAD-box helicase 1" Q92499 2 15591178-15634346 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, mRNA processing, Transcription, Transcription regulation, tRNA processing" "Activator, DNA-binding, Exonuclease, Helicase, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 20 "Neuroblastoma: 4589.7" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB012280, HPA034502, HPA034503" Enhanced Supported Nucleoplasm,Cytosol NA NA 35000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 17: Non-specific - RNA processing" 60 Nucleoplasm Cytosol "CAB012280: , HPA034502: , HPA034503: " "unprognostic (4.37e-2)" "unprognostic (7.21e-2)" "unprognostic (5.81e-2)" "unprognostic (2.54e-2)" "unprognostic (3.04e-1)" "unprognostic (1.92e-1)" "unprognostic (3.96e-2)" "unprognostic (7.57e-2)" "unprognostic (4.54e-2)" "unprognostic (2.93e-2)" "potential prognostic favorable (1.88e-8)" "unprognostic (6.20e-3)" "unprognostic (7.45e-2)" "validated prognostic unfavorable (1.65e-6)" "validated prognostic unfavorable (5.15e-6)" "unprognostic (2.28e-2)" "unprognostic (8.31e-2)" "unprognostic (4.43e-3)" "unprognostic (7.44e-2)" "unprognostic (1.11e-1)" "unprognostic (6.97e-2)" "unprognostic (8.86e-3)" "unprognostic (5.03e-2)" "unprognostic (1.18e-1)" "unprognostic (1.66e-1)" "unprognostic (5.23e-2)" "unprognostic (4.59e-2)" "unprognostic (2.16e-1)" "unprognostic (2.64e-1)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" DDX11 "CHL1, ChlR1, KRG-2, WABS" ENSG00000013573 "DEAD/H-box helicase 11" Q96FC9 12 31073860-31104799 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Isomerase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 33.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 180.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 9135 "Oocytes: 913505.3" "Not detected" "Not detected" HPA065197 Supported Enhanced Nucleoplasm,Nucleoli No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 2 Nucleoplasm Nucleoli "HPA065197: " "unprognostic (6.28e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (1.26e-2)" "unprognostic (1.33e-2)" "unprognostic (9.87e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.16e-3)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (3.58e-6)" "unprognostic (5.42e-3)" "unprognostic (2.13e-1)" "validated prognostic unfavorable (1.28e-5)" "validated prognostic unfavorable (9.08e-4)" "unprognostic (1.37e-2)" "unprognostic (1.68e-1)" "unprognostic (4.03e-1)" "unprognostic (1.70e-1)" "unprognostic (2.41e-1)" "potential prognostic favorable (6.14e-4)" "unprognostic (3.13e-2)" "unprognostic (2.13e-3)" "unprognostic (4.77e-1)" "unprognostic (1.92e-3)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (7.88e-5)" "unprognostic (2.14e-2)" "unprognostic (3.87e-2)" "unprognostic (2.48e-2)" "unprognostic (3.08e-2)" DDX18 "Has1, MrDb" ENSG00000088205 "DEAD-box helicase 18" Q9NVP1 2 117814691-117832377 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 23847843.5" "Low tissue specificity" "Detected in many" "HPA035400, HPA041056" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 4200 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 20: Non-specific - Transcription regulation" 65 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA035400: , HPA041056: " "unprognostic (2.11e-2)" "unprognostic (1.37e-1)" "unprognostic (9.03e-2)" "unprognostic (3.55e-2)" "unprognostic (7.32e-2)" "unprognostic (2.53e-2)" "unprognostic (1.24e-1)" "unprognostic (7.26e-2)" "unprognostic (5.94e-3)" "unprognostic (3.03e-2)" "potential prognostic favorable (5.66e-6)" "unprognostic (3.18e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (8.91e-3)" "unprognostic (1.69e-2)" "unprognostic (3.47e-3)" "unprognostic (5.39e-2)" "unprognostic (2.20e-3)" "unprognostic (2.70e-1)" "unprognostic (7.51e-2)" "unprognostic (9.80e-3)" "unprognostic (4.21e-3)" "unprognostic (1.07e-1)" "unprognostic (3.16e-2)" "unprognostic (3.16e-2)" "unprognostic (7.74e-3)" "unprognostic (1.29e-1)" "unprognostic (4.99e-1)" "unprognostic (2.72e-2)" "unprognostic (5.36e-1)" DDX21 "GURDB, RH-II/GU" ENSG00000165732 "DExD-box helicase 21" Q9NR30 10 68956135-68985068 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, rRNA processing, Transcription" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 574.0;Suprabasal keratinocytes: 576.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 39136532.2" "Low tissue specificity" "Detected in all" "HPA036592, HPA036593" Enhanced Enhanced "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 370000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 345 "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA036592: , HPA036593: " "unprognostic (9.67e-2)" "unprognostic (2.05e-1)" "unprognostic (7.85e-2)" "unprognostic (1.64e-3)" "unprognostic (8.88e-2)" "unprognostic (2.16e-1)" "unprognostic (2.40e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (2.83e-2)" "unprognostic (1.32e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (4.15e-1)" "unprognostic (1.45e-3)" "unprognostic (5.60e-3)" "unprognostic (2.12e-2)" "unprognostic (1.66e-2)" "unprognostic (2.51e-3)" "unprognostic (3.41e-1)" "unprognostic (1.26e-1)" "unprognostic (1.49e-1)" "unprognostic (2.01e-3)" "potential prognostic unfavorable (8.28e-4)" "unprognostic (1.01e-1)" "unprognostic (4.74e-2)" "unprognostic (1.96e-2)" "unprognostic (4.34e-2)" "unprognostic (1.03e-1)" "unprognostic (1.75e-1)" "unprognostic (8.87e-2)" "unprognostic (5.95e-3)" "unprognostic (1.38e-1)" DDX23 "prp28, PRPF28, SNRNP100, U5-100KD" ENSG00000174243 "DEAD-box helicase 23" Q9BUQ8 12 48829756-48852842 "Enzymes, Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38652772.5" "HPA038680, HPA039037" Approved Supported Nucleoplasm,Nucleoli NA NA 11000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 81 "Nucleoplasm, Nucleoli" "HPA038680: , HPA039037: " "unprognostic (1.62e-1)" "unprognostic (2.07e-3)" "unprognostic (1.04e-1)" "unprognostic (4.70e-2)" "unprognostic (2.19e-1)" "unprognostic (1.77e-1)" "unprognostic (4.74e-1)" "unprognostic (8.54e-2)" "unprognostic (2.15e-1)" "unprognostic (5.30e-3)" "potential prognostic favorable (2.32e-4)" "unprognostic (2.32e-3)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (9.57e-6)" "unprognostic (5.63e-3)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (4.26e-3)" "unprognostic (2.50e-2)" "unprognostic (3.16e-1)" "unprognostic (2.02e-1)" "unprognostic (8.22e-2)" "unprognostic (2.10e-1)" "unprognostic (2.10e-2)" "unprognostic (1.40e-1)" "unprognostic (1.13e-1)" "unprognostic (5.05e-3)" "unprognostic (6.40e-2)" "unprognostic (1.78e-1)" "unprognostic (1.00e-1)" "unprognostic (3.24e-1)" "unprognostic (7.43e-3)" DDX28 "FLJ11282, MDDX28" ENSG00000182810 "DEAD-box helicase 28" Q9NUL7 16 68020916-68023232 "Enzymes, Predicted intracellular proteins" "Ribosome biogenesis" "Helicase, Hydrolase, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 33.1;Esophageal basal cells: 24.9;Migrating cytotrophoblasts: 24.7;Syncytiotrophoblasts: 121.0" "Cell type enriched" "Detected in many" 4 "Trophoblast cells: 121.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Pancreas - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 8035415.1" "Tissue enhanced" "Detected in some" "intestine: 100089.1;salivary gland: 105397.3" "HPA041911, HPA053585" Approved Supported Nucleoli,Mitochondria,Cytosol No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 53 Mitochondria "Nucleoli, Cytosol" "HPA041911: , HPA053585: " "unprognostic (3.53e-2)" "unprognostic (7.99e-2)" "unprognostic (2.83e-2)" "unprognostic (2.12e-2)" "unprognostic (2.23e-2)" "unprognostic (5.90e-2)" "unprognostic (2.18e-1)" "potential prognostic favorable (8.49e-4)" "unprognostic (1.68e-2)" "unprognostic (1.40e-2)" "potential prognostic favorable (2.07e-4)" "unprognostic (9.43e-2)" "potential prognostic favorable (3.55e-4)" "unprognostic (3.80e-2)" "unprognostic (3.74e-1)" "unprognostic (8.51e-2)" "unprognostic (1.97e-1)" "unprognostic (9.75e-3)" "unprognostic (2.26e-2)" "unprognostic (1.47e-1)" "unprognostic (1.77e-1)" "unprognostic (3.20e-2)" "unprognostic (1.30e-2)" "unprognostic (7.34e-3)" "unprognostic (4.24e-3)" "unprognostic (2.03e-1)" "unprognostic (3.25e-1)" "unprognostic (7.95e-2)" "unprognostic (9.97e-2)" "unprognostic (6.12e-2)" "unprognostic (1.88e-1)" DDX3X "CAP-Rf, DBX, DDX14, DDX3, HLP2" ENSG00000215301 "DEAD-box helicase 3 X-linked" O00571 X 41333348-41364472 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Chromosome partition, Host-virus interaction, Immunity, Innate immunity, Ribosome biogenesis, Transcription, Transcription regulation, Translation regulation" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1604.6;Neutrophils: 1079.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1604.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA001648, HPA005631, HPA059585" Supported Supported Approved "Plasma membrane,Cytosol" NA NA 120000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 112 Cytosol "Plasma membrane" "HPA001648: , HPA005631: , HPA059585: " "unprognostic (1.51e-1)" "unprognostic (1.04e-2)" "unprognostic (3.85e-1)" "unprognostic (5.89e-2)" "unprognostic (1.21e-3)" "unprognostic (9.44e-2)" "unprognostic (3.28e-1)" "unprognostic (3.60e-3)" "unprognostic (2.73e-2)" "unprognostic (6.15e-3)" "potential prognostic favorable (4.07e-6)" "unprognostic (1.25e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-2)" "unprognostic (8.86e-2)" "unprognostic (3.51e-2)" "unprognostic (7.79e-2)" "unprognostic (8.41e-2)" "unprognostic (1.56e-1)" "unprognostic (1.23e-2)" "unprognostic (5.01e-3)" "unprognostic (6.02e-3)" "unprognostic (2.79e-1)" "unprognostic (4.20e-1)" "potential prognostic favorable (9.09e-4)" "unprognostic (5.28e-2)" "unprognostic (5.14e-2)" "unprognostic (1.92e-1)" "unprognostic (2.00e-1)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" DDX3Y DBY ENSG00000067048 "DEAD-box helicase 3 Y-linked" O15523 Y 12904108-12920478 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 90.4" "Cell type enhanced" "Detected in many" "Early spermatids: 307.2;Hematopoietic stem cells: 270.3;Late spermatids: 1005.1;Megakaryocyte-Erythroid progenitors: 211.8;Neutrophils: 257.9" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 1005.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 140.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001648, HPA005631, HPA059583" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 20 Cytosol "Plasma membrane" "HPA001648: , HPA005631: , HPA059583: " "unprognostic (7.46e-2)" "unprognostic (2.77e-2)" "unprognostic (7.96e-2)" "unprognostic (2.33e-1)" "unprognostic (5.31e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (2.03e-1)" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (7.99e-2)" "unprognostic (4.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.71e-1)" "unprognostic (2.94e-1)" "unprognostic (7.99e-2)" "unprognostic (4.69e-1)" "unprognostic (8.77e-2)" "unprognostic (2.94e-1)" "unprognostic (7.38e-2)" "unprognostic (3.36e-2)" "unprognostic (1.20e-2)" "unprognostic (7.09e-2)" "unprognostic (1.71e-2)" "unprognostic (5.53e-1)" "unprognostic (1.70e-2)" DDX49 "Dbp8, FLJ10432" ENSG00000105671 "DEAD-box helicase 49" Q9Y6V7 19 18919705-18929189 "Enzymes, Essential proteins, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 184.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 184.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1547260.0" "Tissue enhanced" "Detected in some" "lymphoid tissue: 35551.9" "HPA041870, HPA048093" Enhanced Approved Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 Mitochondria "HPA041870: , HPA048093: " "unprognostic (3.23e-2)" "unprognostic (7.65e-2)" "unprognostic (3.41e-1)" "unprognostic (1.12e-2)" "unprognostic (2.27e-1)" "unprognostic (1.19e-1)" "unprognostic (3.44e-1)" "unprognostic (2.92e-1)" "unprognostic (8.60e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (4.76e-3)" "unprognostic (2.69e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (6.28e-6)" "unprognostic (1.33e-2)" "unprognostic (3.02e-2)" "unprognostic (4.79e-2)" "unprognostic (1.59e-2)" "unprognostic (5.38e-2)" "unprognostic (5.51e-2)" "unprognostic (1.58e-1)" "unprognostic (7.35e-2)" "unprognostic (2.50e-1)" "unprognostic (2.42e-3)" "unprognostic (6.79e-2)" "potential prognostic favorable (1.37e-4)" "unprognostic (4.62e-3)" "unprognostic (5.60e-2)" "unprognostic (2.85e-1)" "unprognostic (6.13e-2)" "unprognostic (1.08e-1)" DDX5 "G17P1, HLR1, p68" ENSG00000108654 "DEAD-box helicase 5" P17844 17 64498254-64508199 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB005868, HPA020043, HPA071154" Supported Supported Nucleoplasm,Nucleoli No No 180000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Breast cancer - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 194 "Nucleoplasm, Nucleoli" "CAB005868: , HPA020043: , HPA071154: " "unprognostic (1.16e-2)" "unprognostic (9.27e-2)" "unprognostic (1.75e-1)" "unprognostic (5.77e-3)" "unprognostic (3.08e-2)" "unprognostic (2.52e-1)" "unprognostic (8.23e-2)" "unprognostic (4.53e-1)" "unprognostic (2.13e-1)" "unprognostic (5.90e-2)" "validated prognostic favorable (3.05e-10)" "validated prognostic favorable (3.51e-4)" "unprognostic (1.15e-1)" "unprognostic (2.08e-1)" "unprognostic (1.12e-1)" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (5.72e-2)" "unprognostic (1.50e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (7.38e-2)" "unprognostic (7.31e-2)" "potential prognostic favorable (1.91e-4)" "unprognostic (1.27e-1)" "unprognostic (4.34e-2)" "unprognostic (1.49e-1)" "unprognostic (7.88e-2)" "unprognostic (6.67e-2)" DDX56 NOH61 ENSG00000136271 "DEAD-box helicase 56" Q9NY93 7 44565804-44575051 "Enzymes, Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "Stomach: 1982444.1" "HPA019749, CAB037320" Uncertain Supported "Nucleoli,Mitotic chromosome" Yes NA 100000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 72 Nucleoli "Mitotic chromosome" "CAB037320: , HPA019749: " "unprognostic (3.56e-2)" "unprognostic (1.58e-2)" "unprognostic (4.69e-2)" "unprognostic (5.69e-2)" "unprognostic (4.41e-1)" "unprognostic (1.03e-1)" "unprognostic (7.73e-3)" "unprognostic (3.10e-2)" "unprognostic (3.26e-3)" "unprognostic (5.30e-2)" "unprognostic (1.24e-3)" "unprognostic (1.22e-1)" "unprognostic (8.11e-2)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (8.17e-4)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (6.09e-3)" "unprognostic (2.94e-1)" "unprognostic (8.58e-2)" "unprognostic (2.46e-1)" "unprognostic (3.67e-2)" "unprognostic (1.37e-1)" "unprognostic (5.99e-3)" "unprognostic (4.22e-3)" "unprognostic (2.81e-2)" "unprognostic (2.21e-1)" "unprognostic (4.30e-2)" "unprognostic (1.83e-1)" "unprognostic (2.47e-1)" "unprognostic (1.35e-2)" "unprognostic (1.92e-2)" DDX59 "DKFZP564B1023, ZNHIT5" ENSG00000118197 "DEAD-box helicase 59" Q5T1V6 1 200623896-200669907 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 512381.5" "Group enriched" "Detected in some" "intestine: 1328162.6;lymphoid tissue: 501771.8;salivary gland: 538426.3" HPA047166 Approved Supported "Nucleoplasm,Vesicles,Actin filaments,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 "Nucleoplasm, Actin filaments" "Vesicles, Primary cilium, Primary cilium tip, Centrosome, Basal body" "HPA047166: " "unprognostic (9.45e-2)" "unprognostic (2.19e-1)" "unprognostic (4.23e-2)" "unprognostic (7.93e-2)" "unprognostic (2.75e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (4.30e-3)" "unprognostic (1.63e-1)" "unprognostic (2.25e-2)" "unprognostic (3.30e-2)" "unprognostic (2.91e-1)" "unprognostic (9.13e-2)" "unprognostic (4.16e-2)" "unprognostic (5.02e-1)" "unprognostic (8.15e-2)" "unprognostic (2.10e-1)" "unprognostic (1.48e-1)" "unprognostic (8.56e-3)" "unprognostic (5.74e-2)" "unprognostic (2.94e-1)" "unprognostic (2.98e-1)" "unprognostic (1.97e-2)" "unprognostic (9.88e-2)" "unprognostic (5.91e-2)" "unprognostic (8.92e-2)" "unprognostic (9.01e-2)" "unprognostic (3.07e-1)" "unprognostic (1.57e-1)" "unprognostic (1.12e-1)" "unprognostic (1.75e-1)" DDX6 "HLR2, RCK, Rck/p54" ENSG00000110367 "DEAD-box helicase 6" P26196 11 118747763-118791164 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 86041067.2" "Tissue enhanced" "Detected in all" "lymphoid tissue: 39175841.4" "CAB004668, HPA024201, HPA026644" Approved Supported "Plasma membrane,Midbody,Cytosol,Cytoplasmic bodies" Yes NA 25000 "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 307 "Cytoplasmic bodies" "Plasma membrane, Midbody, Cytosol" "CAB004668: , HPA024201: , HPA026644: " "unprognostic (4.70e-2)" "unprognostic (2.29e-3)" "unprognostic (4.46e-2)" "unprognostic (3.74e-3)" "unprognostic (7.85e-2)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" "unprognostic (1.03e-1)" "unprognostic (3.91e-2)" "unprognostic (1.77e-2)" "potential prognostic favorable (1.10e-5)" "unprognostic (2.08e-3)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (2.37e-1)" "unprognostic (2.54e-1)" "unprognostic (1.09e-3)" "unprognostic (4.63e-2)" "unprognostic (2.78e-2)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (2.57e-2)" "unprognostic (6.79e-2)" "unprognostic (2.78e-1)" "unprognostic (8.54e-2)" "unprognostic (1.91e-2)" "unprognostic (4.54e-3)" "unprognostic (9.20e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-1)" "unprognostic (1.47e-1)" DDX60 FLJ20035 ENSG00000137628 "DExD/H-box helicase 60" Q8IY21 4 168216291-168318883 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "stomach 1: 38.5" "Cell type enriched" "Detected in many" 4 "Foveolar cells: 404.9" "Cell type enriched" "Detected in many" 4 "Gastric glandular cells: 404.9" "Cell type enhanced" "Detected in many" "endothelial cell: 118.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 11323218.8;T-cells: 10647507.4" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17240445.8" HPA046952 Approved Supported "Intermediate filaments,Centrosome,Cytosol" No No "Cluster 33: Non-specific - ATP binding" "Cluster 60: Stomach - Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 68: Foveolar cells - Mucosal defense" 3 Cytosol "Intermediate filaments, Centrosome" "HPA046952: " "unprognostic (1.45e-1)" "unprognostic (1.11e-1)" "unprognostic (1.48e-1)" "unprognostic (2.22e-1)" "unprognostic (1.40e-1)" "unprognostic (2.11e-1)" "unprognostic (8.18e-2)" "unprognostic (2.26e-2)" "unprognostic (6.69e-2)" "unprognostic (2.72e-2)" "potential prognostic favorable (8.87e-5)" "unprognostic (1.31e-3)" "unprognostic (2.23e-1)" "unprognostic (2.84e-2)" "potential prognostic favorable (9.42e-4)" "unprognostic (5.10e-3)" "unprognostic (1.31e-2)" "unprognostic (2.00e-1)" "unprognostic (2.37e-1)" "unprognostic (1.53e-1)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (7.92e-5)" "unprognostic (1.34e-2)" "unprognostic (2.69e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-2)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (8.14e-2)" "unprognostic (3.28e-2)" "unprognostic (6.38e-2)" DECR1 "DECR, SDR18C1" ENSG00000104325 "2,4-dienoyl-CoA reductase 1" Q16698 8 90001405-90053633 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.1" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 432.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1859495364.8" "Tissue enhanced" "Detected in all" "heart muscle: 810898322.7" "HPA023160, HPA023162, HPA023238" Enhanced Supported Mitochondria,Cytosol No No 260000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 Mitochondria Cytosol "HPA023160: , HPA023162: , HPA023238: " "unprognostic (8.48e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-2)" "potential prognostic favorable (3.29e-4)" "unprognostic (1.32e-1)" "unprognostic (8.76e-2)" "unprognostic (7.41e-2)" "unprognostic (9.69e-3)" "unprognostic (8.38e-3)" "unprognostic (9.91e-3)" "potential prognostic favorable (9.96e-5)" "unprognostic (5.60e-2)" "unprognostic (2.45e-1)" "unprognostic (1.93e-3)" "unprognostic (4.39e-3)" "unprognostic (7.78e-2)" "unprognostic (2.99e-1)" "unprognostic (3.11e-1)" "unprognostic (1.54e-1)" "unprognostic (6.04e-2)" "unprognostic (1.18e-2)" "unprognostic (7.19e-2)" "unprognostic (1.73e-1)" "unprognostic (4.85e-2)" "unprognostic (3.48e-3)" "unprognostic (3.38e-3)" "unprognostic (6.00e-2)" "unprognostic (1.17e-1)" "unprognostic (1.51e-1)" "unprognostic (1.49e-1)" "unprognostic (1.45e-1)" DECR2 "PDCR, SDR17C1" ENSG00000242612 "2,4-dienoyl-CoA reductase 2" Q9NUI1 16 401858-412487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 174.4" "Cell type enhanced" "Detected in some" "Astrocytes: 6.7;Bergmann glia: 6.3;Brain excitatory neurons: 3.8;Brain inhibitory neurons: 3.5;Distal convoluted tubule cells: 4.0;Ependymal cells: 4.5;Loop of henle epithelial cells: 5.2;Oligodendrocyte progenitor cells: 4.1;Papillary tip epithelial cells: 4.0;Proximal tubule cells: 24.9;Renal collecting duct intercalated cells: 4.6;Renal collecting duct principal cells: 4.2;Renal connecting tubule cells: 4.4;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "Glial cells: 6.7;Renal nephron cells: 24.9;Secretory gland support: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 45301397.5;Proximal tubules: 50592728.0" "Tissue enriched" "Detected in many" "liver: 25380617.9" HPA047631 Approved Peroxisomes,Microtubules NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 Peroxisomes Microtubules "HPA047631: " "unprognostic (4.04e-2)" "unprognostic (5.15e-2)" "unprognostic (2.71e-1)" "unprognostic (3.99e-1)" "unprognostic (6.47e-2)" "unprognostic (4.50e-2)" "unprognostic (1.19e-1)" "unprognostic (2.92e-1)" "unprognostic (1.48e-1)" "unprognostic (1.92e-1)" "unprognostic (2.84e-3)" "unprognostic (1.62e-1)" "unprognostic (6.97e-3)" "unprognostic (2.28e-2)" "unprognostic (1.70e-3)" "unprognostic (8.16e-2)" "unprognostic (2.43e-2)" "unprognostic (1.71e-1)" "unprognostic (2.39e-1)" "unprognostic (9.95e-2)" "unprognostic (2.58e-1)" "unprognostic (5.05e-2)" "unprognostic (3.81e-2)" "unprognostic (2.19e-1)" "unprognostic (9.43e-2)" "unprognostic (1.32e-1)" "unprognostic (7.93e-2)" "unprognostic (7.77e-2)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "unprognostic (1.13e-2)" DEDD2 FLAME-3 ENSG00000160570 "Death effector domain containing 2" Q8WXF8 19 42198598-42220140 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 110.9;Neutrophils: 173.9;Syncytiotrophoblasts: 211.3" "Cell type enhanced" "Detected in many" "Neutrophils: 173.9;Trophoblast cells: 211.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA043419 Approved Nucleoplasm NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 6 Nucleoplasm "HPA043419: " "unprognostic (2.68e-1)" "unprognostic (6.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.40e-2)" "unprognostic (1.89e-1)" "unprognostic (2.20e-2)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (6.93e-2)" "unprognostic (4.38e-3)" "potential prognostic favorable (6.86e-5)" "unprognostic (2.93e-2)" "unprognostic (7.85e-2)" "unprognostic (8.74e-2)" "unprognostic (3.22e-2)" "unprognostic (6.59e-3)" "unprognostic (8.35e-2)" "unprognostic (2.28e-2)" "unprognostic (1.63e-1)" "unprognostic (2.49e-1)" "unprognostic (2.23e-1)" "unprognostic (6.17e-2)" "unprognostic (2.06e-1)" "unprognostic (3.08e-2)" "unprognostic (2.41e-2)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" "unprognostic (2.04e-1)" "unprognostic (1.63e-1)" "unprognostic (1.27e-2)" "unprognostic (1.22e-1)" DEF6 "IBP, SLAT, SWAP70L" ENSG00000023892 "DEF6 guanine nucleotide exchange factor" Q9H4E7 6 35297818-35321771 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 197.0;Late primary spermatocytes: 97.2;Late spermatids: 252.5;Microglia: 92.7;Neutrophil progenitors: 104.2;Neutrophils: 114.5;NK-cells: 91.7;T-cells: 84.4" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 197.0;Spermatogenic cell types: 252.5" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 110.8;leukocyte: 99.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 58.2;Myeloma: 41.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Kidney - T-cells, Liver - T-cells, Skin - Keratinocyte (other), Spleen - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 17782347.8;T-cells: 33720546.2" "Tissue enriched" "Detected in many" "lymphoid tissue: 26860538.5" "HPA038975, HPA038976" Enhanced Enhanced Nucleoplasm Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 20 Nucleoplasm "HPA038975: , HPA038976: " "unprognostic (1.78e-1)" "validated prognostic favorable (1.16e-4)" "validated prognostic favorable (2.15e-4)" "unprognostic (6.06e-3)" "unprognostic (7.50e-2)" "unprognostic (1.77e-1)" "unprognostic (9.15e-2)" "unprognostic (1.20e-1)" "unprognostic (2.62e-2)" "unprognostic (2.19e-2)" "unprognostic (5.05e-3)" "unprognostic (1.64e-1)" "unprognostic (3.56e-1)" "unprognostic (2.54e-1)" "unprognostic (1.14e-2)" "unprognostic (8.68e-3)" "unprognostic (4.23e-2)" "unprognostic (2.08e-1)" "unprognostic (8.34e-2)" "unprognostic (6.27e-2)" "unprognostic (6.38e-3)" "unprognostic (1.07e-1)" "unprognostic (2.45e-2)" "unprognostic (2.99e-3)" "unprognostic (1.69e-1)" "unprognostic (7.12e-2)" "unprognostic (1.84e-1)" "unprognostic (6.65e-2)" "unprognostic (4.42e-2)" "unprognostic (3.53e-2)" "unprognostic (1.14e-1)" DEFA5 "DEF5, HD-5" ENSG00000164816 "Defensin alpha 5" Q01523 8 7055304-7056739 "Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Defensin, Fungicide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 754 "intestine: 9025.0" "Cell type enriched" "Detected in some" 760 "Paneth cells: 84212.6" "Cell type enriched" "Detected in some" 760 "Secretory gland support: 84212.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 216.0;Colon Adenocarcinoma (TCGA): 216.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 29 "Gastric cancer: 121.3" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "intestine: 36430273.6" "HPA015309, HPA015775, CAB069919" Enhanced Approved Vesicles,Midbody "Secreted to digestive system" Immunity Yes NA 240000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 32: Non-specific - Cell proliferation" "Cluster 15: Non-specific - Protein processing" 1 Vesicles Midbody "CAB069919: , HPA015309: , HPA015775: " "unprognostic (3.14e-2)" "unprognostic (6.41e-2)" "unprognostic (2.40e-1)" "unprognostic (2.60e-1)" "unprognostic (7.09e-3)" "unprognostic (6.37e-3)" "unprognostic (9.21e-2)" DENND3 KIAA0870 ENSG00000105339 "DENN domain containing 3" A2RUS2 8 141117278-141195808 "Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 100.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 301.6;Epicardial cells: 197.9;Microglia: 303.4;monocytes: 136.0;Neutrophil progenitors: 271.7;Neutrophils: 805.4" "Cell type enhanced" "Detected in many" "Alveolar cells: 301.6;Glial cells: 303.4;Neutrophils: 805.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 365.5;endothelial cell: 216.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 34.7;neutrophil: 40.5" "Group enriched" "Detected in many" 5 "granulocytes: 40.5;monocytes: 10.1" "Cancer enhanced" "Detected in all" "Leukemia: 67.4" "Spleen - Neutrophils_2, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 17475249.9;Neutrophils: 9440318.1" "Group enriched" "Detected in some" "lung: 13861076.6;lymphoid tissue: 11209898.1" "HPA024491, HPA041668" Approved Approved Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Vesicles, Cytosol" "HPA024491: , HPA041668: " "unprognostic (2.87e-3)" "unprognostic (1.14e-1)" "unprognostic (5.78e-3)" "unprognostic (1.98e-2)" "unprognostic (1.83e-1)" "unprognostic (3.06e-2)" "unprognostic (3.39e-2)" "unprognostic (4.16e-2)" "unprognostic (6.93e-2)" "unprognostic (7.57e-3)" "unprognostic (2.39e-2)" "unprognostic (2.15e-2)" "unprognostic (1.98e-2)" "unprognostic (4.09e-2)" "unprognostic (4.72e-3)" "unprognostic (4.42e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-2)" "unprognostic (1.68e-1)" "unprognostic (2.71e-2)" "unprognostic (2.47e-2)" "unprognostic (7.73e-3)" "potential prognostic unfavorable (8.75e-4)" "unprognostic (3.77e-2)" "unprognostic (4.21e-1)" "unprognostic (7.71e-3)" "unprognostic (3.44e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-1)" "unprognostic (2.18e-2)" "unprognostic (5.53e-2)" DENND4A "IRLB, MYCPBP" ENSG00000174485 "DENN domain containing 4A" Q7Z401 15 65658046-65792293 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 54.8" "Cell type enhanced" "Detected in all" "Mast cells: 1001.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 5601924.6" "Tissue enhanced" "Detected in many" "lung: 6029509.9" HPA065343 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 35: Non-specific - DNA binding" "Cluster 55: Lymphoma - Immune response" "Cluster 103: Non-specific - Basic cellular processes" 33 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA065343: " "unprognostic (2.98e-2)" "unprognostic (9.94e-2)" "unprognostic (2.14e-2)" "unprognostic (2.45e-1)" "unprognostic (2.14e-1)" "unprognostic (5.83e-3)" "unprognostic (1.96e-1)" "unprognostic (1.77e-2)" "unprognostic (2.05e-1)" "unprognostic (6.76e-3)" "validated prognostic favorable (5.07e-4)" "validated prognostic favorable (9.39e-5)" "unprognostic (2.20e-1)" "unprognostic (2.35e-1)" "unprognostic (1.96e-2)" "unprognostic (2.84e-2)" "unprognostic (4.46e-1)" "unprognostic (2.26e-1)" "unprognostic (2.55e-1)" "unprognostic (1.48e-1)" "unprognostic (1.85e-2)" "unprognostic (1.92e-1)" "unprognostic (2.28e-3)" "unprognostic (1.73e-1)" "unprognostic (1.72e-2)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (9.93e-2)" "unprognostic (2.41e-1)" "unprognostic (5.16e-2)" DEPDC7 ENSG00000121690 "DEP domain containing 7" Q96QD5 11 33015876-33033582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 27.3;kidney: 18.2;liver: 69.2;testis: 26.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 38.6;Early spermatids: 179.7;Enterocytes: 45.1;Extravillous trophoblasts: 77.2;Hepatocytes: 41.2;Late primary spermatocytes: 150.8;Oocytes: 36.8;Schwann cells: 35.0;Tuft cells: 57.6" "Cell type enhanced" "Detected in many" "Secretory gland support: 57.6;Spermatogenic cell types: 179.7;Trophoblast cells: 77.2" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 8.1;committed oligodendrocyte precursor: 9.2;oligodendrocyte: 14.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4222 "Hepatocytes: 306607.7;Proximal tubules: 537827.5" "Tissue enriched" "Detected in single" 70 "intestine: 6960.0" HPA015800 Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoli "Nucleoplasm, Cytosol" "HPA015800: " "unprognostic (1.42e-1)" "unprognostic (1.32e-1)" "unprognostic (3.97e-1)" "unprognostic (6.01e-2)" "unprognostic (3.65e-1)" "unprognostic (6.53e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-2)" "unprognostic (1.90e-1)" "potential prognostic favorable (6.13e-6)" "unprognostic (2.08e-2)" "unprognostic (2.37e-1)" "validated prognostic favorable (2.69e-4)" "validated prognostic favorable (3.35e-4)" "unprognostic (1.70e-1)" "unprognostic (3.64e-2)" "unprognostic (1.68e-2)" "unprognostic (2.87e-2)" "unprognostic (2.93e-2)" "unprognostic (2.16e-3)" "unprognostic (7.84e-3)" "unprognostic (7.84e-3)" "unprognostic (1.93e-1)" "unprognostic (2.68e-1)" "unprognostic (1.38e-1)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (1.55e-1)" DEPTOR "DEP.6, DEPDC6, FLJ12428" ENSG00000155792 "DEP domain containing MTOR interacting protein" Q8TB45 8 119873717-120050918 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 148.1;tongue: 114.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 318.2;Distal convoluted tubule cells: 416.6;Lacrimal acinar cells: 318.9;Loop of henle epithelial cells: 578.3;Myonuclei: 834.3;Pituicytes/FSCs: 448.9;Salivary acinar cells: 320.9" "Cell type enhanced" "Detected in all" "Myocytes: 834.3;Renal nephron cells: 578.3" "Cell type enhanced" "Detected in all" "mammillary body: 269.0;oligodendrocyte: 242.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 11 "myeloid DC: 20.3" "Lineage enriched" "Detected in many" 11 "dendritic cells: 20.3" "Cancer enriched" "Detected in many" 4 "Myeloma: 105.1" "Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 7586938.9;Fallopian tube cells: 6717490.2;Skeletal myofibers: 7152879.8" "Tissue enhanced" "Detected in many" "salivary gland: 3951167.8" "CAB020841, HPA023938, HPA023945, HPA024011" Enhanced Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 14 Mitochondria "Nucleoplasm, Nuclear bodies" "CAB020841: , HPA023938: , HPA023945: , HPA024011: " "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (5.58e-2)" "unprognostic (2.61e-2)" "unprognostic (2.11e-2)" "unprognostic (1.19e-1)" "unprognostic (1.96e-3)" "unprognostic (2.89e-1)" "unprognostic (1.28e-2)" "potential prognostic favorable (6.75e-8)" "unprognostic (3.68e-3)" "unprognostic (7.37e-2)" "unprognostic (2.54e-1)" "unprognostic (1.93e-1)" "unprognostic (2.35e-2)" "unprognostic (3.95e-2)" "unprognostic (3.16e-2)" "unprognostic (1.49e-1)" "unprognostic (6.09e-2)" "unprognostic (1.56e-1)" "unprognostic (1.82e-2)" "unprognostic (2.16e-2)" "unprognostic (4.91e-3)" "unprognostic (1.62e-1)" "unprognostic (2.20e-2)" "unprognostic (3.23e-1)" "unprognostic (7.65e-2)" "unprognostic (2.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.24e-2)" DESI1 "D15Wsu75e, DESI-1, FAM152B, POST, PPPDE2" ENSG00000100418 "Desumoylating isopeptidase 1" Q6ICB0 22 41598028-41621043 "Predicted intracellular proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 935.5;Esophageal apical cells: 584.8;Esophageal suprabasal cells: 225.6;Late primary spermatocytes: 444.3;Late spermatids: 809.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 584.8;Spermatogenic cell types: 935.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Microglia and Neuropil: 11859946.5" "Tissue enriched" "Detected in many" "cerebral cortex: 7913419.6" HPA053415 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 29 Cytosol "Cytokinetic bridge" "HPA053415: " "unprognostic (2.34e-1)" "unprognostic (6.82e-2)" "unprognostic (7.29e-3)" "unprognostic (1.39e-1)" "unprognostic (8.35e-2)" "unprognostic (3.39e-2)" "unprognostic (3.26e-1)" "unprognostic (2.13e-3)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.00e-1)" "unprognostic (2.56e-1)" "unprognostic (7.69e-3)" "unprognostic (5.09e-3)" "unprognostic (1.09e-1)" "unprognostic (1.53e-1)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.26e-1)" "unprognostic (3.70e-2)" "unprognostic (2.59e-2)" "unprognostic (1.80e-2)" "unprognostic (5.16e-3)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.15e-2)" "unprognostic (2.41e-1)" DET1 FLJ10103 ENSG00000140543 "DET1 partner of COP1 E3 ubiquitin ligase" Q7L5Y6 15 88494440-88546681 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 10.2;Bergmann glia: 13.2;Cardiomyocytes: 14.0;Choroid plexus epithelial cells: 16.6;Distal convoluted tubule cells: 28.7;Ependymal cells: 13.7;Loop of henle epithelial cells: 30.5;Oligodendrocyte progenitor cells: 10.9;Oligodendrocytes: 11.6;Papillary tip epithelial cells: 24.4;Podocytes: 32.8;Proximal tubule cells: 20.1;Renal collecting duct intercalated cells: 29.1;Renal collecting duct principal cells: 26.7;Renal connecting tubule cells: 22.8" "Cell type enhanced" "Detected in some" "Ciliated cells: 16.6;Ductal cells: 29.1;Glial cells: 13.2;Myocytes: 14.0;Renal nephron cells: 32.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Large ducts: 2533333.5" "Group enriched" "Detected in some" 38 "fallopian tube: 3896.9;ovary: 3636.9" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 105: Non-specific - Mixed function" 38 Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: " "unprognostic (1.20e-2)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (3.73e-2)" "unprognostic (2.96e-1)" "unprognostic (6.61e-2)" "unprognostic (1.61e-1)" "unprognostic (1.37e-3)" "unprognostic (9.95e-2)" "unprognostic (9.10e-2)" "validated prognostic favorable (1.90e-10)" "validated prognostic favorable (3.60e-4)" "unprognostic (6.27e-2)" "unprognostic (3.60e-3)" "unprognostic (4.79e-2)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (2.05e-1)" "unprognostic (9.65e-2)" "unprognostic (2.45e-1)" "unprognostic (2.51e-2)" "unprognostic (1.08e-1)" "unprognostic (3.25e-1)" "unprognostic (2.53e-1)" "unprognostic (5.11e-2)" "unprognostic (1.17e-1)" "unprognostic (1.64e-1)" "unprognostic (2.71e-2)" "unprognostic (1.81e-1)" "unprognostic (5.63e-2)" "unprognostic (7.23e-2)" DGAT1 "ARGP1, DGAT" ENSG00000185000 "Diacylglycerol O-acyltransferase 1" O75907 8 144314584-144326910 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 41.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 20.4;Astrocytes: 19.0;Bergmann glia: 14.3;Brain excitatory neurons: 15.2;Brain inhibitory neurons: 14.9;Choroid plexus epithelial cells: 14.0;Enterocytes: 21.0;Oligodendrocyte progenitor cells: 23.7;Oligodendrocytes: 13.2;Other brain neurons: 11.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 20.4;Enterocytes: 21.0;Glial cells: 23.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1305326.1" "Tissue enriched" "Detected in many" "intestine: 2363676.6" CAB032853 Enhanced Approved "Nucleoli,Nucleoli rim,Endoplasmic reticulum" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 6 "Endoplasmic reticulum" "Nucleoli, Nucleoli rim" "CAB032853: " "unprognostic (5.29e-2)" "unprognostic (9.75e-3)" "unprognostic (1.91e-1)" "unprognostic (2.65e-2)" "unprognostic (2.87e-2)" "unprognostic (1.99e-1)" "unprognostic (6.02e-2)" "unprognostic (1.11e-1)" "unprognostic (9.95e-2)" "unprognostic (1.76e-2)" "unprognostic (3.06e-3)" "unprognostic (3.06e-1)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "unprognostic (8.10e-2)" "unprognostic (5.61e-2)" "unprognostic (1.07e-1)" "unprognostic (2.76e-2)" "unprognostic (3.34e-1)" "unprognostic (2.67e-1)" "unprognostic (1.20e-1)" "unprognostic (2.13e-1)" "unprognostic (9.71e-3)" "unprognostic (2.22e-1)" "unprognostic (8.83e-2)" "unprognostic (2.93e-1)" "unprognostic (5.87e-2)" "unprognostic (3.51e-2)" "unprognostic (3.40e-1)" "unprognostic (5.51e-2)" "unprognostic (4.10e-1)" DGAT2 ENSG00000062282 "Diacylglycerol O-acyltransferase 2" Q96PD7 11 75759512-75801535 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Glycerol metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adipose tissue: 447.0;breast: 135.2;liver: 309.8;skin 1: 147.4" "Cell type enhanced" "Detected in many" "Adipocytes: 313.4;Early primary spermatocytes: 66.6;Early spermatids: 355.5;Esophageal apical cells: 187.1;Hepatocytes: 144.6;Late primary spermatocytes: 134.4;Late spermatids: 110.7;Neutrophils: 399.2" "Group enriched" "Detected in many" 5 "Adipocytes: 313.4;Apical squamous epithelial cells: 187.1;Hepatocytes: 144.6;Neutrophils: 399.2;Spermatogenic cell types: 355.5" "Cell type enhanced" "Detected in many" "medium spiny neuron: 16.7" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 96.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "eosinophil: 138.1;neutrophil: 350.5" "Lineage enriched" "Detected in many" 16 "granulocytes: 350.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophils_2, Skin - Keratinocyte (granular), Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "basal ganglia: 30.0" "Cell type enriched" "Detected in some" "Hepatocytes: 397261.5" "Tissue enriched" "Detected in single" 3365 "liver: 336540.5" HPA013351 Approved Vesicles,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 29: Neutrophils - Innate immune cellular maintenance" "Vesicles, Cytosol" "HPA013351: " "unprognostic (1.85e-2)" "unprognostic (4.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.44e-2)" "unprognostic (6.67e-2)" "unprognostic (4.34e-1)" "unprognostic (1.60e-1)" "unprognostic (3.47e-1)" "unprognostic (6.98e-2)" "unprognostic (2.95e-1)" "unprognostic (1.38e-2)" "unprognostic (6.16e-2)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (7.96e-3)" "unprognostic (3.48e-3)" "unprognostic (2.47e-1)" "unprognostic (2.87e-2)" "unprognostic (5.92e-3)" "unprognostic (1.37e-1)" "unprognostic (3.39e-2)" "unprognostic (2.78e-1)" "unprognostic (2.15e-1)" "potential prognostic favorable (3.80e-4)" "unprognostic (2.98e-1)" "unprognostic (1.17e-2)" "unprognostic (2.64e-1)" "unprognostic (6.25e-2)" "unprognostic (1.35e-1)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.55e-1)" DGCR8 "C22orf12, DGCRK6, Gy1, pasha" ENSG00000128191 "DGCR8 microprocessor complex subunit" Q8WYQ5 22 20080221-20111877 "Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 101.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 769689.0;Neurons: 771353.1" "Tissue enriched" "Detected in some" "bone marrow: 171411.0" "HPA076916, HPA079351" Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 19 "Nucleoplasm, Nuclear bodies" "HPA076916: , HPA079351: " "unprognostic (2.14e-1)" "unprognostic (4.00e-2)" "unprognostic (1.54e-2)" "unprognostic (5.34e-3)" "unprognostic (2.61e-2)" "unprognostic (5.88e-2)" "unprognostic (1.40e-1)" "unprognostic (5.33e-3)" "unprognostic (4.17e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (6.56e-5)" "unprognostic (2.19e-3)" "unprognostic (1.03e-1)" "unprognostic (4.79e-3)" "unprognostic (2.66e-1)" "unprognostic (9.31e-2)" "unprognostic (9.87e-3)" "unprognostic (7.91e-2)" "unprognostic (7.58e-3)" "unprognostic (9.56e-2)" "unprognostic (4.45e-3)" "unprognostic (7.12e-2)" "unprognostic (4.70e-3)" "unprognostic (4.96e-1)" "unprognostic (6.83e-2)" "unprognostic (2.71e-1)" "unprognostic (6.63e-3)" "unprognostic (8.61e-2)" "unprognostic (2.65e-1)" "unprognostic (3.72e-3)" "unprognostic (8.76e-2)" DHRS2 "HEP27, SDR25C1" ENSG00000100867 "Dehydrogenase/reductase 2" Q13268 14 23630115-23645639 "Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 316.3;urinary bladder: 417.5" "Cell type enriched" "Detected in many" 6 "Urothelial cells: 3414.2" "Cell type enriched" "Detected in many" 6 "Barrier epithelial cells: 3414.2" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.5" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 782.0;Kidney Chromophobe (TCGA): 322.4" "Group enriched" "Detected in some" 5 "hypothalamus: 2.0;midbrain: 2.0;pons: 3.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 226.5;Sarcoma: 227.3" "Pituitary gland - Gonadotropes, Skin - Sebaceous gland cells" "Region enriched" "Detected in single" 4 "cerebellum: 2.4" "Cell type enriched" "Detected in some" "Large ducts: 215574084.4" "Tissue enhanced" "Detected in many" "ovary: 9143176.2;salivary gland: 12522498.9" "HPA053915, HPA069551" Enhanced Supported Nucleoplasm,Mitochondria No NA 4600 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 69: Urothelial cells - Basic cellular functions" 3 Mitochondria Nucleoplasm "HPA053915: , HPA069551: " "unprognostic (2.41e-2)" "unprognostic (4.83e-1)" "unprognostic (9.83e-2)" "unprognostic (3.14e-2)" "unprognostic (2.50e-2)" "unprognostic (3.20e-2)" "unprognostic (8.53e-3)" "unprognostic (6.92e-3)" "unprognostic (3.95e-1)" "potential prognostic unfavorable (8.70e-5)" "unprognostic (2.37e-3)" "unprognostic (5.63e-2)" "unprognostic (7.42e-2)" "unprognostic (2.29e-2)" "unprognostic (2.55e-2)" "unprognostic (2.07e-2)" "unprognostic (3.79e-2)" "unprognostic (3.30e-2)" "unprognostic (1.22e-2)" "unprognostic (4.80e-2)" "unprognostic (4.35e-3)" "unprognostic (1.15e-1)" "unprognostic (2.39e-1)" "unprognostic (4.41e-1)" "unprognostic (4.60e-2)" "unprognostic (1.44e-1)" "unprognostic (4.00e-1)" "unprognostic (2.83e-1)" "unprognostic (1.23e-2)" DHRS3 "RDH17, retSDR1, Rsdr1, SDR1, SDR16C1" ENSG00000162496 "Dehydrogenase/reductase 3" O75911 1 12567910-12618210 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 238.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 594.8;Late spermatids: 561.2;Podocytes: 548.7;Prostatic hillock cells: 644.6;Salivary duct cells: 420.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "astrocyte: 70.8;central nervous system macrophage: 119.0;choroid plexus epithelial cell: 102.1;endothelial cell: 69.6;ependymal cell: 61.2;fibroblast: 57.2;leukocyte: 72.0;vascular associated smooth muscle cell: 50.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 87.0;MAIT T-cell: 63.2;memory CD4 T-cell: 47.0;memory CD8 T-cell: 41.0;myeloid DC: 24.1;naive CD4 T-cell: 79.4;naive CD8 T-cell: 50.2;NK-cell: 41.2" "Group enriched" "Detected in many" 5 "dendritic cells: 24.1;NK-cells: 41.2;T-cells: 87.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 5691909.1;Keratinocytes: 5539417.9" "Group enriched" "Detected in many" "intestine: 1568681.7;liver: 4663735.3" HPA010844 Supported Approved Nucleoli,Mitochondria NA NA "Cluster 11: T-cells - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 69: Skin cancer - ECM organization" "Cluster 51: Secretory epithelial cells - Mixed function" 4 Mitochondria Nucleoli "HPA010844: " "unprognostic (4.18e-2)" "unprognostic (1.18e-1)" "unprognostic (3.75e-1)" "unprognostic (2.53e-1)" "unprognostic (4.70e-3)" "unprognostic (6.42e-2)" "unprognostic (1.35e-1)" "unprognostic (4.91e-2)" "unprognostic (1.64e-1)" "unprognostic (1.94e-1)" "validated prognostic favorable (7.22e-7)" "validated prognostic favorable (2.16e-4)" "unprognostic (3.50e-1)" "unprognostic (3.87e-2)" "unprognostic (1.35e-1)" "unprognostic (1.99e-2)" "unprognostic (1.13e-1)" "unprognostic (7.16e-2)" "unprognostic (6.76e-3)" "unprognostic (4.33e-2)" "unprognostic (8.68e-2)" "unprognostic (3.96e-3)" "unprognostic (5.77e-2)" "unprognostic (4.42e-1)" "unprognostic (1.20e-1)" "unprognostic (5.26e-2)" "unprognostic (2.94e-2)" "unprognostic (5.92e-2)" "unprognostic (2.86e-1)" "unprognostic (5.37e-3)" "unprognostic (3.99e-2)" DHRS7 "retDSR4, SDR34C1" ENSG00000100612 "Dehydrogenase/reductase 7" Q9Y394 14 60144119-60169856 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 634.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 357.8;Enterocytes: 789.5;Epididymal clear cells: 420.5;Neutrophils: 407.9;Prostatic glandular cells: 1078.1;Salivary acinar cells: 449.4" "Cell type enhanced" "Detected in all" "Enterocytes: 789.5;Glandular cells: 1078.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Kidney Chromophobe (TCGA): 823.9;Prostate Adenocarcinoma (TCGA): 854.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Pancreas - Macrophages, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA031121, HPA078401" Enhanced Approved Nucleoplasm,Mitochondria No No "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 11 "Nucleoplasm, Mitochondria" "HPA031121: , HPA078401: " "unprognostic (3.54e-2)" "unprognostic (5.06e-2)" "unprognostic (3.59e-1)" "unprognostic (3.12e-2)" "unprognostic (1.13e-1)" "unprognostic (1.50e-1)" "unprognostic (4.90e-1)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (9.00e-5)" "unprognostic (2.88e-1)" "potential prognostic favorable (5.38e-9)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (5.29e-2)" "unprognostic (1.93e-1)" "unprognostic (3.10e-3)" "unprognostic (7.37e-2)" "unprognostic (2.03e-1)" "unprognostic (6.45e-3)" "unprognostic (5.10e-3)" "unprognostic (7.24e-2)" "unprognostic (9.85e-2)" "unprognostic (1.24e-2)" "unprognostic (1.50e-1)" "unprognostic (4.33e-2)" "unprognostic (1.58e-2)" "unprognostic (6.26e-2)" "unprognostic (9.19e-3)" "unprognostic (2.54e-1)" "unprognostic (9.41e-2)" "unprognostic (7.12e-2)" DHRSX "DHRS5X, DHRS5Y, DHRSXY, DHRSY, SDR46C1, SDR7C6" ENSG00000169084 "Dehydrogenase/reductase X-linked" Q8N5I4 X 2219506-2502805 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 983.7" "Cell type enhanced" "Detected in all" "Neutrophils: 983.7" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 1835004.6" "Tissue enriched" "Detected in many" "intestine: 1002005.2" "HPA003035, HPA075955" Approved Uncertain "Mitotic spindle,Cytosol" "Secreted to blood" Enzyme Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 46: Brainstem - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 15 Cytosol "Mitotic spindle" "HPA003035: , HPA075955: " "unprognostic (2.55e-1)" "unprognostic (1.29e-2)" "unprognostic (4.56e-2)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (1.08e-1)" "unprognostic (5.73e-2)" "unprognostic (1.12e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (7.84e-4)" "unprognostic (1.58e-1)" "unprognostic (1.65e-1)" "unprognostic (3.35e-1)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (2.02e-2)" "unprognostic (1.78e-1)" "unprognostic (2.10e-1)" "unprognostic (2.72e-1)" "unprognostic (1.52e-1)" "unprognostic (3.96e-2)" "unprognostic (8.80e-2)" "unprognostic (2.80e-1)" "unprognostic (2.84e-1)" "unprognostic (6.15e-3)" "unprognostic (7.75e-2)" "unprognostic (3.17e-2)" "unprognostic (2.74e-1)" "unprognostic (3.04e-1)" "unprognostic (5.30e-2)" DHTKD1 "CMT2Q, DKFZP762M115, KIAA1630, MGC3090" ENSG00000181192 "Dehydrogenase E1 and transketolase domain containing 1" Q96HY7 10 12068954-12123221 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 121.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 400.6;Proximal tubule cells: 180.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 400.6;Renal nephron cells: 180.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 49038971.9" "Group enriched" "Detected in many" "intestine: 28610023.6;liver: 36456962.9" "HPA037949, HPA037950, HPA066098" Enhanced Supported Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 Mitochondria "HPA037949: , HPA037950: , HPA066098: " "unprognostic (1.26e-2)" "unprognostic (1.91e-2)" "unprognostic (4.04e-1)" "unprognostic (3.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.33e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (3.40e-6)" "unprognostic (1.39e-3)" "unprognostic (4.48e-2)" "potential prognostic favorable (2.45e-6)" "unprognostic (1.46e-2)" "unprognostic (2.85e-2)" "unprognostic (4.80e-3)" "unprognostic (1.28e-3)" "unprognostic (9.53e-2)" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (3.15e-2)" "unprognostic (1.09e-1)" "unprognostic (3.51e-1)" "unprognostic (2.04e-1)" "unprognostic (2.87e-1)" "unprognostic (9.23e-2)" "unprognostic (3.91e-2)" "unprognostic (9.80e-2)" "unprognostic (2.52e-1)" "unprognostic (1.34e-1)" "unprognostic (2.54e-3)" "unprognostic (4.10e-2)" DHX35 "C20orf15, DDX35, FLJ22759, KAIA0875" ENSG00000101452 "DEAH-box helicase 35" Q9H5Z1 20 38962299-39039723 "Enzymes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 91.0;Myonuclei: 77.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 1866809.5" "Tissue enriched" "Detected in some" "lymphoid tissue: 685109.9" "HPA054451, HPA062700" Uncertain Approved "Nucleoplasm,Nuclear bodies,Centrosome" No No "Cluster 14: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 84: Apical squamous epithelium - Cornification" 18 "Nuclear bodies" "Nucleoplasm, Centrosome" "HPA054451: , HPA062700: " "unprognostic (2.60e-2)" "unprognostic (5.99e-2)" "unprognostic (1.83e-2)" "unprognostic (4.85e-2)" "unprognostic (3.73e-3)" "unprognostic (1.74e-1)" "unprognostic (1.88e-1)" "unprognostic (1.58e-2)" "unprognostic (2.00e-2)" "unprognostic (6.38e-2)" "unprognostic (2.25e-3)" "unprognostic (7.41e-3)" "unprognostic (1.78e-1)" "unprognostic (4.32e-3)" "unprognostic (8.96e-3)" "unprognostic (1.65e-1)" "unprognostic (3.38e-2)" "unprognostic (1.26e-1)" "unprognostic (1.35e-2)" "unprognostic (1.40e-2)" "unprognostic (3.54e-1)" "unprognostic (1.76e-2)" "unprognostic (2.02e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (5.77e-4)" "unprognostic (9.46e-2)" "unprognostic (1.40e-1)" "unprognostic (4.07e-3)" "unprognostic (2.78e-1)" "unprognostic (8.75e-3)" "unprognostic (3.80e-2)" DHX36 "DDX36, KIAA1488, MLEL1, RHAU" ENSG00000174953 "DEAH-box helicase 36" Q9H2U1 3 154272546-154324487 "Enzymes, Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiviral defense, Differentiation, Immunity, Innate immunity, Transcription, Transcription regulation, Translation regulation, Transport" "Activator, Developmental protein, DNA-binding, Helicase, Hydrolase, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 582.9;Late spermatids: 455.4;Syncytiotrophoblasts: 426.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 582.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Neurons: 10261581.1" "Low tissue specificity" "Detected in many" HPA035399 Approved Supported Nucleoplasm,Cytosol NA NA 5000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 17 "Nucleoplasm, Cytosol" "HPA035399: " "unprognostic (1.33e-1)" "unprognostic (1.37e-1)" "unprognostic (1.50e-1)" "unprognostic (6.67e-3)" "unprognostic (1.10e-1)" "unprognostic (1.44e-1)" "unprognostic (7.54e-2)" "unprognostic (9.45e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (2.48e-4)" "potential prognostic favorable (7.62e-6)" "unprognostic (5.50e-3)" "unprognostic (1.68e-1)" "unprognostic (2.75e-2)" "unprognostic (3.79e-2)" "unprognostic (3.13e-3)" "unprognostic (4.42e-3)" "unprognostic (2.71e-1)" "unprognostic (1.96e-2)" "unprognostic (1.37e-1)" "unprognostic (3.94e-1)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (5.44e-2)" "unprognostic (1.02e-2)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "unprognostic (1.88e-1)" "unprognostic (2.69e-1)" "unprognostic (2.85e-2)" "unprognostic (7.48e-2)" DHX38 "DDX38, hPrp16, KIAA0224, PRP16, PRPF16" ENSG00000140829 "DEAH-box helicase 38" Q92620 16 72093613-72112912 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" "heart muscle: 33551374.2;kidney: 18823724.9" "HPA041347, HPA041604" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 35 Nucleoplasm "HPA041347: , HPA041604: " "unprognostic (6.61e-2)" "unprognostic (2.34e-1)" "unprognostic (9.26e-2)" "unprognostic (7.36e-3)" "unprognostic (2.08e-2)" "unprognostic (2.38e-1)" "unprognostic (1.64e-1)" "potential prognostic favorable (1.72e-5)" "unprognostic (7.55e-3)" "unprognostic (5.67e-2)" "unprognostic (1.49e-3)" "unprognostic (5.18e-2)" "unprognostic (2.21e-1)" "unprognostic (1.17e-3)" "unprognostic (2.12e-2)" "unprognostic (1.25e-1)" "unprognostic (3.29e-2)" "unprognostic (6.78e-2)" "unprognostic (6.70e-2)" "unprognostic (5.45e-2)" "unprognostic (5.36e-2)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (3.62e-3)" "unprognostic (3.67e-1)" "unprognostic (7.48e-2)" "unprognostic (4.89e-2)" "unprognostic (9.77e-2)" "unprognostic (3.26e-1)" "unprognostic (1.68e-1)" "unprognostic (2.11e-2)" DHX8 "DDX8, Dhr2, HRH1, PRP22, PRPF22" ENSG00000067596 "DEAH-box helicase 8" Q14562 17 43483865-43610338 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 2698881.3" "Tissue enriched" "Detected in many" "skin: 10335810.2" HPA049285 Approved Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 69 Nucleoplasm "Nuclear bodies" "HPA049285: " "unprognostic (4.21e-3)" "unprognostic (1.55e-1)" "unprognostic (4.69e-1)" "unprognostic (5.57e-2)" "unprognostic (2.17e-1)" "unprognostic (1.13e-3)" "unprognostic (3.80e-1)" "unprognostic (6.10e-3)" "unprognostic (3.81e-1)" "unprognostic (3.64e-2)" "unprognostic (9.19e-2)" "unprognostic (1.15e-1)" "unprognostic (2.03e-3)" "potential prognostic unfavorable (9.78e-4)" "unprognostic (1.34e-2)" "unprognostic (1.75e-2)" "unprognostic (2.32e-2)" "unprognostic (3.01e-1)" "unprognostic (6.25e-3)" "unprognostic (1.38e-2)" "unprognostic (2.47e-2)" "unprognostic (2.35e-1)" "unprognostic (2.02e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (7.99e-2)" "unprognostic (2.49e-1)" "unprognostic (7.73e-2)" "unprognostic (1.90e-1)" "unprognostic (1.62e-1)" "unprognostic (1.61e-2)" DHX9 "DDX9, LKP, RHA" ENSG00000135829 "DExH-box helicase 9" Q08211 1 182839347-182887982 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, DNA replication, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, mRNA processing, mRNA splicing, mRNA transport, RNA-mediated gene silencing, Transcription, Transcription regulation, Transcription termination, Translation regulation, Transport" "Activator, DNA-binding, Helicase, Hydrolase, RNA-binding" "Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 816312664.5" "Low tissue specificity" "Detected in all" "CAB011819, HPA028050, HPA055684" Supported Enhanced Nucleoplasm,Nucleoli NA NA 670000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 302 Nucleoplasm Nucleoli "CAB011819: , HPA028050: , HPA055684: " "unprognostic (4.66e-2)" "unprognostic (2.86e-2)" "unprognostic (1.44e-1)" "unprognostic (5.80e-2)" "unprognostic (2.11e-2)" "unprognostic (2.06e-1)" "unprognostic (5.09e-2)" "unprognostic (1.70e-2)" "unprognostic (1.06e-1)" "unprognostic (1.38e-2)" "potential prognostic favorable (2.14e-7)" "unprognostic (3.68e-3)" "unprognostic (7.47e-2)" "unprognostic (2.82e-2)" "unprognostic (8.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.06e-2)" "unprognostic (3.31e-1)" "unprognostic (2.63e-2)" "unprognostic (7.60e-2)" "unprognostic (1.90e-1)" "unprognostic (3.93e-3)" "unprognostic (1.17e-1)" "unprognostic (7.05e-2)" "unprognostic (3.83e-2)" "unprognostic (1.68e-1)" "unprognostic (8.67e-2)" "unprognostic (2.37e-1)" "unprognostic (2.71e-1)" "unprognostic (9.96e-2)" "unprognostic (1.57e-1)" DIABLO "DFNA64, DIABLO-S, FLJ10537, FLJ25049, SMAC" ENSG00000184047 "Diablo IAP-binding mitochondrial protein" Q9NR28 12 122207663-122227456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 13.0;Bergmann glia: 14.4;Brain excitatory neurons: 20.6;Brain inhibitory neurons: 17.8;Choroid plexus epithelial cells: 16.2;Ependymal cells: 12.7;Microglia: 14.0;Oligodendrocyte progenitor cells: 14.9;Oligodendrocytes: 19.1;Other brain neurons: 22.5" "Group enriched" "Detected in some" 4 "Ciliated cells: 16.2;Glial cells: 19.1;Neuronal cells: 22.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Large ducts: 476509657.6" "Low tissue specificity" "Detected in all" "HPA001825, CAB003857, CAB016688" Supported Supported "Mitochondria,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 60 Mitochondria "Cytosol, Flagellar centriole, Mid piece, Principal piece, End piece" "CAB003857: , CAB016688: , HPA001825: " "unprognostic (2.35e-1)" "unprognostic (3.34e-2)" "unprognostic (7.12e-3)" "unprognostic (6.86e-3)" "unprognostic (9.47e-2)" "unprognostic (1.26e-2)" "unprognostic (2.85e-1)" "unprognostic (4.88e-2)" "unprognostic (2.13e-3)" "potential prognostic unfavorable (5.07e-4)" "potential prognostic favorable (4.99e-6)" "unprognostic (2.42e-1)" "unprognostic (1.49e-1)" "validated prognostic unfavorable (1.31e-4)" "validated prognostic unfavorable (3.81e-6)" "unprognostic (1.42e-3)" "unprognostic (2.26e-2)" "unprognostic (4.72e-2)" "unprognostic (2.51e-2)" "unprognostic (7.94e-2)" "unprognostic (2.51e-3)" "unprognostic (3.86e-2)" "unprognostic (1.67e-2)" "unprognostic (2.64e-1)" "unprognostic (1.40e-1)" "unprognostic (8.84e-2)" "unprognostic (4.16e-1)" "unprognostic (3.49e-1)" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (6.17e-2)" DIDO1 "BYE1, C20orf158, DATF1, DIO-1, DIO1, dJ885L7.8, FLJ11265, KIAA0333" ENSG00000101191 "Death inducer-obliterator 1" Q9BTC0 20 62877738-62937952 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 47142718.1" "Low tissue specificity" "Detected in many" "CAB004374, HPA049904" Supported Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 62: Non-specific - Plasma proteins" "Cluster 7: Non-specific - Transcription" 42 Nucleoplasm "Vesicles, Cytosol" "CAB004374: , HPA049904: " "potential prognostic favorable (6.81e-4)" "unprognostic (3.35e-3)" "unprognostic (3.23e-1)" "unprognostic (1.25e-2)" "unprognostic (5.57e-2)" "unprognostic (1.73e-1)" "unprognostic (4.00e-1)" "unprognostic (4.78e-2)" "unprognostic (7.52e-3)" "unprognostic (3.45e-2)" "unprognostic (2.64e-3)" "unprognostic (3.77e-1)" "unprognostic (2.36e-2)" "unprognostic (1.48e-3)" "unprognostic (2.16e-1)" "unprognostic (9.45e-3)" "unprognostic (4.26e-2)" "unprognostic (2.33e-1)" "unprognostic (7.71e-2)" "unprognostic (4.52e-1)" "unprognostic (1.26e-1)" "unprognostic (3.29e-2)" "unprognostic (5.10e-3)" "unprognostic (1.02e-1)" "unprognostic (1.89e-3)" "unprognostic (2.45e-3)" "unprognostic (1.63e-2)" "unprognostic (2.74e-1)" "unprognostic (1.57e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-1)" DIO3 TXDI3 ENSG00000197406 "Iodothyronine deiodinase 3" P55073 14 101560139-101563452 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.8;placenta: 18.3" "Group enriched" "Detected in some" 5 "Adipocytes: 46.7;Fibroblasts: 28.8;Syncytiotrophoblasts: 104.4" "Group enriched" "Detected in some" 5 "Adipocytes: 46.7;Fibroblasts: 28.8;Trophoblast cells: 104.4" "Cell type enriched" "Detected in single" 4 "pericyte: 3.1" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.4" "Region enhanced" "Detected in some" "thalamus: 7.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 8.1" "Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "amygdala: 6.1;hippocampal formation: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA073684 Supported Vesicles NA NA "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 108: Fibroblasts - ECM organization" 12 Vesicles "HPA073684: " "unprognostic (5.51e-2)" "unprognostic (4.83e-3)" "unprognostic (1.15e-2)" "unprognostic (6.95e-3)" "unprognostic (2.44e-1)" "unprognostic (1.53e-1)" "unprognostic (1.98e-1)" "unprognostic (9.77e-2)" "potential prognostic favorable (8.86e-4)" "unprognostic (1.16e-1)" "unprognostic (1.99e-2)" "unprognostic (8.93e-2)" DIP2A "C21orf106, Dip2, KIAA0184" ENSG00000160305 "Disco interacting protein 2 homolog A" Q14689 21 46458891-46570015 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Ligase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 322.1;Neutrophil progenitors: 297.7;NK-cells: 279.2;Rod photoreceptor cells: 396.2" "Cell type enhanced" "Detected in all" "Neuronal cells: 396.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "pancreas: 5262523.8" "HPA044692, HPA052516" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites,Mitochondria" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 Nucleoplasm "Plasma membrane, Actin filaments, Focal adhesion sites, Mitochondria" "HPA044692: , HPA052516: " "unprognostic (1.00e-1)" "unprognostic (1.41e-2)" "unprognostic (1.40e-2)" "unprognostic (7.64e-3)" "unprognostic (2.27e-1)" "unprognostic (1.48e-1)" "unprognostic (2.48e-1)" "unprognostic (8.14e-3)" "unprognostic (8.87e-3)" "unprognostic (3.41e-2)" "potential prognostic favorable (1.05e-5)" "unprognostic (7.86e-3)" "unprognostic (1.80e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (5.90e-2)" "unprognostic (7.41e-2)" "unprognostic (3.37e-1)" "unprognostic (6.43e-2)" "unprognostic (3.16e-3)" "unprognostic (4.86e-2)" "unprognostic (2.20e-1)" "unprognostic (3.67e-3)" "unprognostic (1.58e-1)" "unprognostic (7.25e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.15e-1)" "unprognostic (2.03e-1)" "unprognostic (6.30e-2)" "unprognostic (8.83e-2)" DIP2B "FLJ34278, KIAA1463" ENSG00000066084 "Disco interacting protein 2 homolog B" Q9P265 12 50504985-50748657 "Human disease related genes, Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 778.7;Neutrophils: 1190.2;Ocular epithelial cells: 658.0;Oligodendrocytes: 1072.9" "Cell type enhanced" "Detected in all" "Glial cells: 1072.9;Neutrophils: 1190.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1310.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 34813472.6" "Low tissue specificity" "Detected in many" "HPA038472, HPA046133, HPA056045" Enhanced Approved "Endoplasmic reticulum" No No "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Endoplasmic reticulum" "HPA038472: , HPA046133: , HPA056045: " "unprognostic (1.56e-3)" "unprognostic (2.71e-3)" "unprognostic (4.06e-1)" "unprognostic (5.83e-2)" "unprognostic (3.39e-2)" "unprognostic (4.78e-2)" "unprognostic (7.28e-2)" "unprognostic (7.64e-3)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (3.81e-4)" "potential prognostic favorable (1.13e-5)" "unprognostic (9.05e-3)" "unprognostic (1.75e-1)" "unprognostic (2.72e-2)" "unprognostic (2.05e-2)" "unprognostic (5.91e-3)" "unprognostic (9.82e-3)" "unprognostic (1.38e-3)" "unprognostic (1.04e-1)" "unprognostic (6.46e-2)" "unprognostic (4.41e-2)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (8.95e-5)" "unprognostic (7.74e-2)" "unprognostic (1.26e-1)" "unprognostic (1.92e-2)" "unprognostic (2.96e-2)" "unprognostic (1.39e-2)" "unprognostic (1.05e-1)" "unprognostic (1.74e-2)" "unprognostic (2.26e-1)" DIPK1B "C9orf136, FAM69B, MGC20262" ENSG00000165716 "Divergent protein kinase domain 1B" Q5VUD6 9 136712572-136724742 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 57.7;Megakaryocyte progenitors: 44.8;Megakaryocyte-Erythroid progenitors: 54.3;Megakaryocytes: 74.2;Melanocytes: 33.3;Platelets: 126.9;Retinal horizontal cells: 36.1;Vascular endothelial cells: 48.2" "Cell type enhanced" "Detected in many" "Megakaryocytes: 74.2;Platelets: 126.9;Stem cells: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "memory B-cell: 1.0;naive B-cell: 2.8;plasmacytoid DC: 1.0" "Group enriched" "Detected in many" 9 "B-cells: 2.8;dendritic cells: 1.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 2193982.2" "Not detected" "Not detected" HPA054443 Approved "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 34: B-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 35: RS4;11 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 "Nuclear bodies" "Nucleoplasm, Vesicles" "HPA054443: " "unprognostic (2.98e-2)" "unprognostic (7.54e-2)" "unprognostic (1.22e-2)" "unprognostic (3.66e-3)" "unprognostic (2.60e-1)" "unprognostic (1.60e-1)" "unprognostic (1.02e-2)" "unprognostic (3.40e-2)" "unprognostic (3.03e-1)" "unprognostic (2.37e-2)" "unprognostic (1.06e-2)" "unprognostic (3.74e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (2.73e-1)" "unprognostic (2.90e-1)" "unprognostic (2.40e-3)" "unprognostic (5.93e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (5.13e-5)" "unprognostic (8.84e-2)" "unprognostic (1.88e-1)" "unprognostic (1.49e-1)" "unprognostic (1.06e-1)" "unprognostic (3.90e-1)" "unprognostic (4.84e-2)" "unprognostic (2.95e-2)" "unprognostic (1.75e-1)" "unprognostic (7.76e-2)" DIS3L "DIS3L1, FLJ38088, KIAA1955, MGC4562" ENSG00000166938 "DIS3 like exosome 3'-5' exoribonuclease" Q8TF46 15 66293217-66333898 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Pancreatic islets: 10148869.4" "Tissue enriched" "Detected in many" "lung: 1748694.0" "HPA040475, HPA041805" Approved Supported "Plasma membrane,Centrosome,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 33 "Centrosome, Basal body, Cytosol" "Plasma membrane" "HPA040475: , HPA041805: " "unprognostic (1.51e-1)" "unprognostic (4.76e-2)" "unprognostic (3.63e-1)" "unprognostic (1.45e-1)" "unprognostic (7.12e-2)" "unprognostic (2.40e-1)" "unprognostic (3.73e-1)" "unprognostic (2.64e-1)" "unprognostic (2.90e-1)" "unprognostic (1.74e-2)" "unprognostic (4.79e-3)" "unprognostic (2.29e-3)" "unprognostic (3.85e-2)" "unprognostic (1.66e-1)" "unprognostic (3.39e-2)" "unprognostic (1.35e-2)" "unprognostic (1.83e-1)" "unprognostic (1.37e-1)" "unprognostic (5.37e-2)" "unprognostic (6.15e-3)" "unprognostic (2.65e-1)" "unprognostic (2.47e-3)" "unprognostic (1.76e-1)" "unprognostic (3.13e-1)" "unprognostic (4.86e-2)" "unprognostic (3.02e-1)" "unprognostic (9.24e-2)" "unprognostic (1.51e-1)" "unprognostic (1.59e-1)" "unprognostic (2.50e-1)" "unprognostic (1.20e-1)" DISC1 ENSG00000162946 "DISC1 scaffold protein" Q9NRI5 1 231626790-232041272 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Wnt signaling pathway" "Developmental protein" Schizophrenia "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 3199.9;Microglia: 1143.7;Neutrophils: 600.1;Oligodendrocyte progenitor cells: 792.5;Rod photoreceptor cells: 866.5" "Cell type enhanced" "Detected in many" "Glial cells: 1143.7;Myocytes: 3199.9;Neuronal cells: 866.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1466.3;oligodendrocyte precursor cell: 865.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 1730 "lymphoid tissue: 172955.2" HPA048911 Supported "Intermediate filaments,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 178 "Intermediate filaments, Cytosol" "HPA048911: " "unprognostic (1.55e-3)" "unprognostic (2.27e-1)" "unprognostic (1.70e-1)" "unprognostic (1.90e-1)" "unprognostic (8.78e-2)" "unprognostic (1.04e-1)" "unprognostic (5.60e-2)" "unprognostic (9.60e-2)" "unprognostic (8.83e-2)" "potential prognostic favorable (9.81e-5)" "unprognostic (1.79e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-2)" "unprognostic (7.93e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (4.13e-2)" "unprognostic (1.41e-1)" "unprognostic (3.31e-1)" "unprognostic (2.15e-1)" "unprognostic (2.25e-2)" "unprognostic (4.57e-2)" "unprognostic (4.41e-2)" "unprognostic (2.90e-2)" "unprognostic (1.81e-2)" "unprognostic (4.79e-3)" "unprognostic (4.69e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" DKK3 "CRRL, REIC, RIG" ENSG00000050165 "Dickkopf WNT signaling pathway inhibitor 3" Q9UBP4 11 11956207-12009769 "Plasma proteins, Predicted secreted proteins" "Wnt signaling pathway" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 371.6;heart muscle: 1240.0" "Cell type enriched" "Detected in many" 4 "Müller glia: 1893.7" "Cell type enriched" "Detected in many" 4 "Glial cells: 1893.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 135.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 7.1;memory CD8 T-cell: 4.4" "Lineage enriched" "Detected in single" 72 "T-cells: 7.1" "Cancer enhanced" "Detected in many" "Brain cancer: 311.7" "Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 4023931.7;Microglia and Neuropil: 3244981.8;Neurons: 4111744.6" "Tissue enriched" "Detected in many" "cerebral cortex: 35939267.7" "HPA011868, CAB024949" Approved Supported "Nuclear bodies,Vesicles,Cytosol" "Secreted in other tissues" "Developmental protein" No No 20000000 "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 6 Vesicles "Nuclear bodies, Cytosol" "CAB024949: , HPA011868: " "unprognostic (3.57e-1)" "unprognostic (1.12e-1)" "unprognostic (6.77e-2)" "unprognostic (1.06e-1)" "unprognostic (2.51e-1)" "unprognostic (2.04e-1)" "unprognostic (1.84e-3)" "unprognostic (2.42e-2)" "unprognostic (6.48e-3)" "unprognostic (1.81e-1)" "validated prognostic favorable (7.36e-5)" "validated prognostic favorable (3.37e-4)" "unprognostic (1.12e-1)" "unprognostic (5.22e-2)" "unprognostic (3.32e-2)" "unprognostic (5.73e-2)" "unprognostic (1.46e-1)" "unprognostic (1.75e-1)" "unprognostic (2.99e-1)" "unprognostic (1.50e-2)" "unprognostic (2.00e-2)" "unprognostic (5.24e-2)" "unprognostic (2.27e-2)" "unprognostic (1.37e-1)" "unprognostic (3.87e-1)" "potential prognostic favorable (2.61e-4)" "unprognostic (7.37e-2)" "unprognostic (7.32e-3)" "unprognostic (3.96e-1)" "unprognostic (1.43e-2)" "unprognostic (2.36e-1)" DKKL1 "CT34, SGY-1" ENSG00000104901 "Dickkopf like acrosomal protein 1" Q9UK85 19 49361783-49375116 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 299 "testis: 352.3" "Group enriched" "Detected in some" 116 "Early spermatids: 2507.9;Late primary spermatocytes: 1665.2;Late spermatids: 3112.0" "Cell type enriched" "Detected in many" 168 "Spermatogenic cell types: 3112.0" "Cell type enhanced" "Detected in some" "ependymal cell: 3.0" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 6 "memory B-cell: 1.7" "Lineage enriched" "Detected in single" 17 "B-cells: 1.7" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025410, HPA047194" Enhanced Approved "Vesicles,Acrosome,Equatorial segment,Mid piece" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 42 "Vesicles, Acrosome, Equatorial segment" "Mid piece" "CAB025410: , HPA047194: " "unprognostic (1.11e-1)" "unprognostic (4.16e-1)" "unprognostic (3.64e-3)" "unprognostic (1.09e-1)" "unprognostic (2.50e-1)" "unprognostic (3.18e-2)" "unprognostic (2.79e-1)" "unprognostic (6.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.12e-2)" DLAT "DLTA, E2, PDC-E2" ENSG00000150768 "Dihydrolipoamide S-acetyltransferase" P10515 11 112025408-112064404 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 83.5" "Cell type enhanced" "Detected in many" "Adipocytes: 172.1;Cardiomyocytes: 206.4" "Cell type enhanced" "Detected in all" "Adipocytes: 172.1;Myocytes: 206.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 421558817.8" "Group enriched" "Detected in all" "cerebral cortex: 102090446.2;heart muscle: 262886967.3;skeletal muscle: 128978959.8" "CAB003782, HPA040786, HPA062766" Supported Supported "Mitochondria,Connecting piece" NA NA 16000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 32 Mitochondria "Connecting piece" "CAB003782: , HPA040786: , HPA062766: " "unprognostic (4.60e-2)" "unprognostic (5.85e-3)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (6.21e-3)" "unprognostic (2.20e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-1)" "unprognostic (6.98e-2)" "unprognostic (5.79e-3)" "potential prognostic favorable (2.14e-10)" "unprognostic (2.61e-2)" "unprognostic (3.00e-3)" "potential prognostic unfavorable (3.42e-5)" "unprognostic (1.34e-2)" "unprognostic (3.39e-3)" "unprognostic (2.28e-2)" "unprognostic (2.99e-1)" "unprognostic (2.78e-1)" "unprognostic (2.00e-1)" "unprognostic (7.63e-3)" "unprognostic (6.44e-3)" "unprognostic (3.65e-1)" "unprognostic (8.76e-2)" "unprognostic (5.65e-3)" "unprognostic (1.63e-1)" "unprognostic (3.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.44e-1)" "unprognostic (1.20e-1)" "unprognostic (6.94e-2)" DLC1 "ARHGAP7, DLC-1, HP, p122-RhoGAP, STARD12" ENSG00000164741 "DLC1 Rho GTPase activating protein" Q96QB1 8 13083361-13604610 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1635.4;Adrenal medulla cells: 872.2;Bergmann glia: 762.0;Cardiomyocytes: 609.6;Fibro-adipogenic progenitors: 1550.1;Leydig cells: 992.7;Oligodendrocytes: 935.0;Pericytes: 2360.9;Pituicytes/FSCs: 1344.7;Schwann cells: 956.9;Vascular smooth muscle cells: 892.6" "Cell type enhanced" "Detected in many" "Adipocytes: 1635.4;Fibro-adipogenic progenitors: 1550.1;Glial cells: 1344.7;Mural cells: 2360.9" "Group enriched" "Detected in all" 4 "pericyte: 9442.6;vascular associated smooth muscle cell: 3776.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 4.3;non-classical monocyte: 1.1" "Group enriched" "Detected in many" 19 "granulocytes: 4.3;monocytes: 1.1" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Capillaries: 1892512.2" "Tissue enriched" "Detected in some" "intestine: 854855.8" "HPA017753, HPA061655, CAB080186" Uncertain Supported "Endoplasmic reticulum,Vesicles,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 110: Mural cells - ECM organization" 5 Cytosol "Endoplasmic reticulum, Vesicles" "CAB080186: , HPA017753: , HPA061655: " "unprognostic (1.13e-2)" "unprognostic (1.59e-1)" "unprognostic (1.14e-1)" "unprognostic (2.78e-1)" "unprognostic (4.39e-2)" "unprognostic (1.71e-3)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (1.49e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (9.34e-5)" "unprognostic (4.63e-3)" "unprognostic (2.34e-1)" "unprognostic (2.64e-2)" "unprognostic (3.03e-2)" "unprognostic (4.30e-3)" "unprognostic (9.01e-2)" "unprognostic (3.85e-3)" "unprognostic (2.62e-1)" "unprognostic (2.23e-2)" "unprognostic (6.58e-3)" "unprognostic (7.78e-3)" "unprognostic (6.05e-2)" "unprognostic (9.45e-2)" "unprognostic (2.90e-1)" "unprognostic (2.38e-2)" "unprognostic (7.23e-2)" "unprognostic (1.03e-3)" "unprognostic (1.40e-2)" "unprognostic (1.90e-1)" "unprognostic (6.20e-2)" DLD "DLDH, E3, GCSL, LAD, OGDC-E3" ENSG00000091140 "Dihydrolipoamide dehydrogenase" P09622 7 107891162-107931730 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 215.8;tongue: 228.7" "Cell type enhanced" "Detected in all" "Epicardial cells: 263.8;Parietal cells: 399.5" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 399.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 652457309.8" "Tissue enhanced" "Detected in all" "heart muscle: 412463693.6" HPA044849 Supported Approved "Nucleoplasm,Cytokinetic bridge,Primary cilium,Mitochondria,Principal piece" Yes NA 8900000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 48 Mitochondria "Nucleoplasm, Cytokinetic bridge, Primary cilium, Principal piece" "HPA044849: " "unprognostic (3.44e-1)" "unprognostic (4.05e-3)" "unprognostic (1.33e-2)" "unprognostic (2.74e-1)" "unprognostic (1.45e-2)" "unprognostic (2.63e-2)" "unprognostic (6.68e-2)" "unprognostic (1.97e-2)" "unprognostic (1.44e-1)" "unprognostic (7.87e-3)" "potential prognostic favorable (1.06e-8)" "unprognostic (8.15e-2)" "unprognostic (7.64e-3)" "unprognostic (2.17e-1)" "unprognostic (1.19e-3)" "unprognostic (9.74e-3)" "unprognostic (3.59e-1)" "unprognostic (2.35e-1)" "unprognostic (1.15e-1)" "unprognostic (3.00e-3)" "unprognostic (7.93e-2)" "unprognostic (2.34e-1)" "unprognostic (1.20e-1)" "unprognostic (2.27e-1)" "unprognostic (1.42e-1)" "unprognostic (1.74e-2)" "unprognostic (2.61e-1)" "unprognostic (3.29e-1)" "unprognostic (1.73e-1)" "unprognostic (1.06e-2)" "unprognostic (5.63e-2)" DLG1 "dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97" ENSG00000075711 "Discs large MAGUK scaffold protein 1" Q12959 3 197042560-197299330 "Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 2027.4" "Cell type enhanced" "Detected in all" "Glial cells: 2027.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 2251.0;oligodendrocyte: 2396.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "cerebral cortex: 107895849.6" "CAB016307, HPA069593" Supported Approved "Vesicles,Plasma membrane,Basal body" NA NA 9500 "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 75 Vesicles "Plasma membrane, Basal body" "CAB016307: , HPA069593: " "unprognostic (6.62e-2)" "unprognostic (2.29e-2)" "unprognostic (2.42e-2)" "unprognostic (4.40e-3)" "unprognostic (3.00e-1)" "unprognostic (4.57e-3)" "unprognostic (8.65e-2)" "unprognostic (3.52e-1)" "unprognostic (1.69e-1)" "unprognostic (1.21e-3)" "potential prognostic favorable (4.02e-5)" "unprognostic (2.43e-1)" "unprognostic (1.48e-1)" "unprognostic (7.17e-2)" "unprognostic (6.79e-2)" "unprognostic (1.13e-1)" "unprognostic (8.54e-3)" "unprognostic (1.46e-1)" "unprognostic (7.96e-2)" "unprognostic (3.08e-2)" "unprognostic (7.32e-3)" "unprognostic (2.94e-3)" "unprognostic (3.42e-3)" "unprognostic (6.12e-2)" "unprognostic (4.72e-2)" "unprognostic (1.18e-2)" "unprognostic (3.90e-2)" "unprognostic (3.01e-1)" "unprognostic (3.81e-1)" "unprognostic (4.44e-2)" "unprognostic (3.14e-1)" DLG4 "PSD-95, PSD95, SAP-90, SAP90" ENSG00000132535 "Discs large MAGUK scaffold protein 4" P78352 17 7187187-7219841 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 211.2;retina: 200.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 48.6;Cone photoreceptor cells: 209.1;Retinal bipolar cells: 64.8;Rod photoreceptor cells: 141.9" "Cell type enriched" "Detected in many" 4 "Neuronal cells: 209.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 28.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1336960 "Astrocytes and Neuropil: 104196307.5;Microglia and Neuropil: 173269346.2;Neurons: 123622273.3" "Tissue enriched" "Detected in some" "cerebral cortex: 197582381.6" "CAB001999, CAB002000, HPA010122, HPA071006" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 78 "Nucleoplasm, Centrosome, Basal body" "Plasma membrane, Primary cilium, Primary cilium tip, Cytosol" "CAB001999: , CAB002000: , HPA010122: , HPA071006: " "unprognostic (1.24e-1)" "unprognostic (5.94e-2)" "unprognostic (2.91e-1)" "unprognostic (4.86e-2)" "unprognostic (7.69e-2)" "unprognostic (1.07e-1)" "unprognostic (2.09e-2)" "unprognostic (8.02e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-2)" "unprognostic (2.31e-2)" "unprognostic (9.33e-2)" "unprognostic (7.07e-2)" "unprognostic (3.59e-3)" "unprognostic (5.72e-3)" "unprognostic (3.67e-2)" "unprognostic (6.83e-3)" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.05e-2)" "unprognostic (3.85e-1)" "potential prognostic favorable (3.85e-4)" "unprognostic (7.64e-3)" "unprognostic (1.24e-1)" "unprognostic (9.42e-2)" "unprognostic (7.68e-2)" "unprognostic (4.41e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-1)" "unprognostic (9.84e-2)" "unprognostic (3.21e-1)" DLGAP3 "DAP3, SAPAP3" ENSG00000116544 "DLG associated protein 3" O95886 1 34865436-34929650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 43.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 55.0;Brain inhibitory neurons: 69.3;Cone photoreceptor cells: 31.1;Early spermatids: 28.1;Gonadotrophs: 19.1;Hofbauer cells: 21.6;Late primary spermatocytes: 22.2;Late spermatids: 30.8;Other brain neurons: 32.3;Retinal amacrine cells: 38.9;Retinal ganglion cells: 30.9;Retinal horizontal cells: 28.0" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 21.6;Neuronal cells: 69.3;Pituitary endocrine cells: 19.1;Spermatogenic cell types: 30.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.3" "Adipose visceral - Macrophages, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 81892 "Astrocytes and Neuropil: 7058326.6;Microglia and Neuropil: 13393747.5;Neurons: 4115423.4" "Tissue enriched" "Detected in single" 359493 "cerebral cortex: 35949331.4" "HPA026445, HPA027304" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody" Yes NA "Cluster 13: Non-specific - Mitochondria" "Cluster 78: Brain - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Endoplasmic reticulum, Plasma membrane" Midbody "HPA026445: , HPA027304: " "unprognostic (2.99e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (5.51e-4)" "unprognostic (2.46e-1)" "unprognostic (7.82e-3)" "unprognostic (2.34e-1)" "unprognostic (1.42e-2)" DLGAP5 "DLG1, DLG7, HURP, KIAA0008" ENSG00000126787 "DLG associated protein 5" Q15398 14 55148112-55191608 "Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 28.0;lymphoid tissue: 39.1;testis: 16.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 39.3;Early primary spermatocytes: 58.4;Erythrocyte progenitors: 233.0;Late primary spermatocytes: 71.9;Megakaryocyte progenitors: 81.2;Monocyte progenitors: 161.5;Neutrophil progenitors: 63.2;Oocytes: 280.9" "Cell type enhanced" "Detected in many" "Erythrocytes: 233.0;Mononuclear phagocytes: 161.5;Oocytes: 280.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 5.4" "Lineage enriched" "Detected in many" 5 "T-cells: 5.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in some" "Oocytes: 13245803.2" "Tissue enriched" "Detected in single" 1532 "bone marrow: 153184.0" "HPA005546, HPA071028" Enhanced Supported "Mitotic spindle,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" 22 Cytosol "Mitotic spindle" "HPA005546: , HPA071028: " "unprognostic (2.67e-3)" "unprognostic (1.32e-1)" "unprognostic (4.87e-2)" "unprognostic (5.48e-2)" "unprognostic (1.75e-3)" "unprognostic (1.39e-1)" "unprognostic (1.24e-1)" "unprognostic (7.09e-2)" "unprognostic (2.26e-2)" "potential prognostic unfavorable (9.43e-5)" "validated prognostic unfavorable (5.92e-6)" "validated prognostic unfavorable (5.02e-4)" "validated prognostic unfavorable (5.64e-6)" "validated prognostic unfavorable (9.30e-9)" "potential prognostic unfavorable (2.27e-5)" "unprognostic (7.56e-3)" "unprognostic (2.99e-2)" "unprognostic (8.77e-2)" "unprognostic (2.32e-1)" "unprognostic (2.78e-2)" "validated prognostic unfavorable (1.28e-5)" "validated prognostic unfavorable (6.12e-4)" "unprognostic (1.39e-1)" "unprognostic (1.62e-2)" "unprognostic (1.81e-1)" "unprognostic (5.90e-2)" "unprognostic (7.61e-2)" "unprognostic (1.72e-1)" "unprognostic (2.04e-1)" DLK2 "EGFL9, MGC2487" ENSG00000171462 "Delta like non-canonical Notch ligand 2" Q6UY11 6 43450352-43456632 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 11.7;prostate: 12.4;skin 1: 12.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 17.0;Basal prostatic cells: 50.8;Breast myoepithelial cells: 80.1;Epididymal basal cells: 70.1;Esophageal basal cells: 34.8;Respiratory basal cells: 42.0;Retinal horizontal cells: 22.0;Salivary basal cells: 33.9;Salivary myoepithelial cells: 29.7" "Group enriched" "Detected in many" 5 "Basal cells: 70.1;Neuronal cells: 22.0;Secretory gland support: 80.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 18.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 38.6" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061223, HPA068672, HPA070955" Uncertain Approved Nucleoplasm,Nucleoli,Vesicles No No 23000 "Cluster 2: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" Nucleoplasm "Nucleoli, Vesicles" "HPA061223: , HPA068672: , HPA070955: " "unprognostic (1.55e-1)" "unprognostic (7.33e-3)" "unprognostic (1.92e-1)" "unprognostic (3.26e-1)" "unprognostic (2.53e-1)" "unprognostic (2.93e-1)" "unprognostic (2.73e-3)" "unprognostic (1.61e-1)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (6.24e-2)" "unprognostic (1.32e-3)" "unprognostic (9.95e-2)" "unprognostic (5.86e-2)" "potential prognostic favorable (1.20e-4)" "unprognostic (7.44e-2)" "unprognostic (1.71e-2)" "unprognostic (1.50e-1)" "unprognostic (7.41e-2)" "unprognostic (1.49e-3)" "unprognostic (1.41e-3)" "unprognostic (5.69e-2)" "unprognostic (2.72e-2)" DLL3 SCDO1 ENSG00000090932 "Delta like canonical Notch ligand 3" Q9NYJ7 19 39498895-39508481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 27.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 46.4;Early primary spermatocytes: 17.3;Epididymal basal cells: 13.0;Oligodendrocyte progenitor cells: 49.3;Oocytes: 96.7;Other brain neurons: 12.2;Undifferentiated spermatogonia: 27.3" "Group enriched" "Detected in many" 4 "Glial cells: 49.3;Oocytes: 96.7;Spermatogenic cell types: 46.4" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 67.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 60.2;Skin Cutaneous Melanoma (TCGA): 26.8" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.6;naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 13 "B-cells: 2.6;T-cells: 1.4" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.9;skin cancer: 27.5" "Testis - Spermatogonia" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024559, HPA056533" Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA024559: , HPA056533: " "unprognostic (8.13e-2)" "unprognostic (1.43e-1)" "unprognostic (4.14e-2)" "unprognostic (7.22e-2)" "potential prognostic favorable (6.19e-4)" "unprognostic (2.92e-2)" "unprognostic (1.49e-1)" "unprognostic (4.00e-2)" "unprognostic (4.37e-2)" "unprognostic (1.73e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (4.99e-5)" DMGDH ME2GLYDH ENSG00000132837 "Dimethylglycine dehydrogenase" Q9UI17 5 78997564-79236038 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 18 "kidney: 158.2;liver: 265.4" "Cell type enhanced" "Detected in many" "Adipocytes: 185.6;Distal convoluted tubule cells: 150.5;Gonadotrophs: 132.9;Hepatocytes: 251.3;Loop of henle epithelial cells: 156.3;Proximal tubule cells: 229.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 251.3;Renal nephron cells: 229.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 39.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 17.0;Liver Hepatocellular Carcinoma (TCGA): 32.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Adrenocortical cancer: 8.5;Kidney cancer: 9.2;liver cancer: 3.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Hepatocytes: 441939040.2;Proximal tubules: 702180462.6" "Tissue enriched" "Detected in some" "liver: 196215699.7" "HPA036441, HPA036442, HPA077849" Enhanced Supported Mitochondria NA NA 1300000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" Mitochondria "HPA036441: , HPA036442: , HPA077849: " "unprognostic (3.83e-2)" "unprognostic (1.45e-1)" "unprognostic (4.64e-1)" "unprognostic (1.95e-1)" "validated prognostic favorable (1.10e-10)" "validated prognostic favorable (8.83e-4)" "unprognostic (8.15e-3)" "validated prognostic favorable (1.71e-4)" "validated prognostic favorable (1.57e-4)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (4.06e-2)" "unprognostic (8.42e-2)" DMRT2 ENSG00000173253 "Doublesex and mab-3 related transcription factor 2" Q9Y5R5 9 1049858-1057552 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "kidney: 32.6;lymphoid tissue: 17.8;parathyroid gland: 39.1;skeletal muscle: 12.2" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 265.4;Medullary thymic epithelial cells: 45.6;Myosatellite cells: 31.5;Renal collecting duct intercalated cells: 192.7;Respiratory ionocytes: 144.8;Salivary ionocytes: 90.5" "Group enriched" "Detected in many" 4 "Ductal cells: 192.7;Ionocytes: 144.8;Reproductive supporting cells: 265.4" "Cell type enriched" "Detected in some" 7 "oligodendrocyte: 16.7" "Cancer enriched" "Detected in many" 19 "Kidney Chromophobe (TCGA): 239.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 5.8" "Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebral cortex: 2.5" "Cell type enriched" "Detected in single" 106760 "Alveolar cell types: 10676033.3" "Tissue enriched" "Detected in single" 151627 "pancreas: 15162709.8" "HPA003498, HPA029297" Uncertain Approved "Nucleoplasm,Nucleoli,Vesicles,Centriolar satellite" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Nucleoplasm, Nucleoli" "Vesicles, Centriolar satellite" "HPA003498: , HPA029297: " "unprognostic (1.02e-2)" "unprognostic (8.98e-2)" "potential prognostic favorable (7.33e-4)" "unprognostic (1.01e-1)" "unprognostic (6.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.79e-2)" "unprognostic (1.11e-1)" "unprognostic (2.86e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (2.37e-2)" "unprognostic (1.02e-2)" "unprognostic (1.67e-2)" "unprognostic (4.96e-2)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" DMRTC1 ENSG00000269502 "DMRT like family C1" Q5HYR2 X 72872025-72943837 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 12.0;pituitary gland: 12.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.1;Brain inhibitory neurons: 1.0;Cone photoreceptor cells: 2.1;Early primary spermatocytes: 4.6;Gonadotrophs: 2.2;Lactotrophs: 2.1;Oligodendrocyte progenitor cells: 1.1;Other brain neurons: 1.1;Rod photoreceptor cells: 1.0;Sertoli cells: 2.2;Somatotrophs: 1.7;Thyrotrophs: 1.7" "Cell type enhanced" "Detected in some" "Neuronal cells: 2.1;Pituitary endocrine cells: 2.2;Reproductive supporting cells: 2.2;Spermatogenic cell types: 4.6" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 16.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 73 "Neurons: 7290.1" "Not detected" "Not detected" "HPA046874, HPA046992" Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 3: Early primary spermatocytes - Early meiosis" Nucleoplasm "Intermediate filaments" "HPA046874: , HPA046992: " "unprognostic (3.91e-1)" DMRTC1B ENSG00000184911 "DMRT like family C1B" Q5HYR2 X 72776890-72848803 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.8;pituitary gland: 16.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 2.2;Brain inhibitory neurons: 2.5;Choroid plexus epithelial cells: 2.0;Gonadotrophs: 4.3;Lactotrophs: 4.2;Other brain neurons: 2.1;Pituitary stem cells: 2.1;Retinal amacrine cells: 2.1;Somatotrophs: 3.7;Thyrotrophs: 3.4" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 10.6;Neuronal cells: 2.5;Pituitary endocrine cells: 4.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 73 "Neurons: 7290.1" "Not detected" "Not detected" "HPA046874, HPA046992" Uncertain Approved "Nucleoplasm,Intermediate filaments" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "Intermediate filaments" "HPA046874: , HPA046992: " "unprognostic (3.58e-2)" "unprognostic (6.73e-2)" "unprognostic (8.82e-2)" "unprognostic (9.88e-3)" "unprognostic (1.99e-2)" "unprognostic (1.28e-1)" "unprognostic (1.89e-3)" "unprognostic (1.29e-1)" "unprognostic (1.91e-2)" DNA2 "DNA2L, KIAA0083" ENSG00000138346 "DNA replication helicase/nuclease 2" P51530 10 68414064-68472121 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, Endonuclease, Helicase, Hydrolase, Multifunctional enzyme, Nuclease" "Disease variant, Dwarfism, Ectodermal dysplasia, Hypotrichosis, Intellectual disability, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 44.6;Erythrocyte progenitors: 102.5;Megakaryocyte progenitors: 70.7;Monocyte progenitors: 63.6;Neutrophil progenitors: 58.3" "Cell type enhanced" "Detected in many" "Erythrocytes: 102.5;Megakaryocytes: 70.7;Mononuclear phagocytes: 63.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.9" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.9" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 65 "Granulosa cells: 6531.1" "Tissue enriched" "Detected in single" 1112 "skeletal muscle: 111204.4" "HPA037487, HPA057526" Approved Supported Mitochondria No Yes "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 23 Mitochondria "HPA037487: , HPA057526: " "unprognostic (1.31e-2)" "unprognostic (2.17e-1)" "unprognostic (1.75e-2)" "unprognostic (2.67e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (3.84e-4)" "unprognostic (3.23e-3)" "potential prognostic unfavorable (3.38e-6)" "unprognostic (1.03e-2)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (7.11e-5)" "unprognostic (3.61e-1)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (1.44e-2)" "unprognostic (9.28e-2)" "unprognostic (6.42e-2)" "unprognostic (1.52e-1)" "unprognostic (3.11e-1)" "unprognostic (6.09e-2)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (5.20e-2)" "unprognostic (1.69e-2)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (1.36e-1)" "unprognostic (3.24e-1)" "unprognostic (1.26e-1)" DNAAF2 "C14orf104, CILD10, FLJ10563, KTU, PF13" ENSG00000165506 "Dynein axonemal assembly factor 2" Q9NVR5 14 49625174-49635244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 7338789.3" "Group enriched" "Detected in some" 29175 "fallopian tube: 3490829.9;lymphoid tissue: 2344122.3" "HPA002894, HPA004113" Enhanced Approved "Nucleoli,Golgi apparatus,Primary cilium,Basal body,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 8 "Basal body, Cytosol" "Nucleoli, Golgi apparatus, Primary cilium" "HPA002894: , HPA004113: " "unprognostic (9.48e-2)" "unprognostic (2.05e-1)" "unprognostic (1.73e-1)" "unprognostic (1.05e-1)" "unprognostic (6.51e-3)" "unprognostic (2.90e-3)" "unprognostic (1.15e-2)" "unprognostic (2.15e-1)" "unprognostic (4.28e-2)" "potential prognostic favorable (8.49e-7)" "unprognostic (4.13e-3)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (1.66e-1)" "unprognostic (5.33e-1)" "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (2.32e-1)" "unprognostic (7.55e-2)" "unprognostic (3.89e-2)" "potential prognostic favorable (8.18e-4)" "unprognostic (5.05e-2)" "unprognostic (5.78e-2)" "unprognostic (2.97e-1)" "unprognostic (3.24e-1)" "unprognostic (1.37e-2)" "unprognostic (1.66e-3)" DNAAF5 "CILD18, FLJ20397, FLJ25564, FLJ31671, FLJ39381, HEATR2" ENSG00000164818 "Dynein axonemal assembly factor 5" Q86Y56 7 726699-786475 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 76.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fallopian tube cells: 25195319.2" "Tissue enhanced" "Detected in many" "fallopian tube: 4393129.5;intestine: 6292086.1" "HPA020243, HPA060196" Uncertain Supported Nucleoli,Microtubules,Cytosol NA NA 4600 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 27 Cytosol "Nucleoli, Microtubules" "HPA020243: , HPA060196: " "unprognostic (1.01e-1)" "unprognostic (2.04e-2)" "unprognostic (8.13e-3)" "unprognostic (1.66e-1)" "unprognostic (4.86e-2)" "unprognostic (6.41e-2)" "unprognostic (6.64e-3)" "unprognostic (1.08e-3)" "unprognostic (6.04e-3)" "potential prognostic favorable (9.00e-4)" "unprognostic (1.77e-1)" "unprognostic (5.23e-3)" "unprognostic (2.79e-3)" "unprognostic (1.84e-3)" "potential prognostic unfavorable (4.29e-4)" "unprognostic (1.32e-1)" "unprognostic (5.99e-2)" "unprognostic (3.83e-2)" "unprognostic (1.46e-1)" "unprognostic (9.62e-2)" "unprognostic (3.69e-3)" "unprognostic (6.81e-3)" "unprognostic (9.44e-3)" "unprognostic (8.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.18e-1)" "unprognostic (3.24e-1)" "unprognostic (1.14e-1)" "unprognostic (3.25e-2)" DNAAF6 "CXorf41, MGC35261, NYSAR97, PIH1D3, TWISTER" ENSG00000080572 "Dynein axonemal assembly factor 6" Q9NQM4 X 107206611-107244247 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 3.8;fallopian tube: 10.2;testis: 11.1" "Cell type enhanced" "Detected in some" "Early spermatids: 174.4;Endometrial ciliated cells: 61.1;Ependymal cells: 32.7;Epididymal efferent duct ciliated cells: 40.3;Fallopian tube ciliated cells: 97.0;Late primary spermatocytes: 147.7;Respiratory ciliated cells: 150.0" "Group enriched" "Detected in some" 35 "Ciliated cells: 150.0;Spermatogenic cell types: 174.4" "Cell type enriched" "Detected in some" 8 "ependymal cell: 45.9" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Region enhanced" "Detected in some" "midbrain: 4.0" "Cell type enriched" "Detected in single" 7185 "Fallopian tube cells: 718548.4" "Tissue enriched" "Detected in single" 3816 "fallopian tube: 381559.0" "HPA051099, HPA072496" Enhanced Approved "Nucleoplasm,Golgi apparatus,Primary cilium,Primary cilium tip,Basal body,Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 107: Ciliated cells - Cilia assembly & function" 11 "Golgi apparatus, Primary cilium, Acrosome" "Nucleoplasm, Primary cilium tip, Basal body, Cytosol, Equatorial segment" "HPA051099: , HPA072496: " "unprognostic (2.45e-1)" DNAAF9 "C20orf194, DKFZp434N061" ENSG00000088854 "Dynein axonemal assembly factor 9" Q5TEA3 20 3249306-3407669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 486.5;Distal convoluted tubule cells: 653.4" "Cell type enhanced" "Detected in all" "Renal nephron cells: 653.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 709348.5" "Group enriched" "Detected in some" 71 "cerebral cortex: 8846.4;fallopian tube: 5434.8" "HPA052103, HPA067418" Approved Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Nucleoli fibrillar center, Cytosol" "HPA052103: , HPA067418: " "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-2)" "unprognostic (5.40e-2)" "unprognostic (1.40e-2)" "unprognostic (7.17e-2)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (7.77e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (4.35e-5)" "unprognostic (1.13e-3)" "unprognostic (2.66e-1)" "unprognostic (8.53e-3)" "unprognostic (1.60e-1)" "unprognostic (2.19e-2)" "unprognostic (6.87e-2)" "unprognostic (1.86e-3)" "unprognostic (5.82e-2)" "unprognostic (3.71e-2)" "unprognostic (6.92e-2)" "unprognostic (1.83e-3)" "unprognostic (2.92e-3)" "unprognostic (2.86e-1)" "unprognostic (6.64e-3)" "unprognostic (1.25e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-2)" "unprognostic (2.76e-1)" "unprognostic (1.27e-1)" "unprognostic (4.29e-3)" DNAH14 "C1orf67, DKFZp781B1548, Dnahc14, HL-18, HL18, MGC27277" ENSG00000185842 "Dynein axonemal heavy chain 14" Q0VDD8 1 224896262-225399292 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 18.5" "Cell type enhanced" "Detected in many" "Early spermatids: 359.7;Gonadotrophs: 374.6;Lactotrophs: 479.0;Retinal amacrine cells: 372.0;Somatotrophs: 438.7;Thyrotrophs: 448.4" "Cell type enhanced" "Detected in all" "Pituitary endocrine cells: 479.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Keratinocytes: 652336.8" "Tissue enriched" "Detected in single" 106 "ovary: 10559.2" "HPA027718, HPA028545, HPA031379" Uncertain Approved "Golgi apparatus,Centrosome,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 21: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Centrosome, Basal body" "Golgi apparatus" "HPA027718: , HPA028545: , HPA031379: " "unprognostic (1.25e-3)" "unprognostic (3.52e-1)" "unprognostic (5.20e-1)" "unprognostic (7.45e-2)" "unprognostic (2.71e-1)" "unprognostic (1.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.42e-3)" "unprognostic (2.90e-2)" "validated prognostic unfavorable (9.46e-6)" "validated prognostic unfavorable (1.08e-4)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (1.94e-2)" "unprognostic (1.77e-3)" "unprognostic (5.88e-3)" "unprognostic (2.87e-3)" "unprognostic (1.39e-1)" "unprognostic (9.06e-3)" "unprognostic (4.06e-1)" "unprognostic (5.96e-2)" "unprognostic (4.48e-3)" "unprognostic (2.19e-2)" "unprognostic (2.56e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (3.11e-2)" "unprognostic (1.87e-1)" "unprognostic (4.36e-2)" "unprognostic (4.93e-2)" DNAH2 "DNHD3, FLJ46675, KIAA1503" ENSG00000183914 "Dynein axonemal heavy chain 2" Q9P225 17 7717744-7833742 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "fallopian tube: 12.3;parathyroid gland: 9.9;retina: 19.2;testis: 6.2" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.8;Ependymal cells: 204.4;Epicardial cells: 38.7;Epididymal efferent duct ciliated cells: 44.1;Fallopian tube ciliated cells: 108.0;Respiratory ciliated cells: 255.2;Rod photoreceptor cells: 256.5" "Group enriched" "Detected in many" 6 "Ciliated cells: 255.2;Neuronal cells: 256.5" "Cell type enriched" "Detected in all" 6 "ependymal cell: 211.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatic stellate cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 48066 "Collecting ducts: 4664202.6;Fallopian tube cells: 4949013.5" "Tissue enriched" "Detected in single" 112710 "fallopian tube: 11270984.3" HPA067103 Enhanced Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Flagellar centriole,End piece" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Microtubules, Primary cilium, Flagellar centriole, End piece" "Cytokinetic bridge, Mitotic spindle, Basal body" "HPA067103: " "unprognostic (1.19e-2)" "unprognostic (5.47e-2)" "unprognostic (1.28e-1)" "unprognostic (5.56e-2)" "unprognostic (1.80e-1)" "unprognostic (2.12e-1)" "unprognostic (5.00e-2)" "unprognostic (1.33e-2)" "unprognostic (1.83e-1)" "unprognostic (1.71e-1)" "unprognostic (1.25e-1)" "unprognostic (7.56e-3)" "unprognostic (1.68e-1)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (5.90e-4)" "unprognostic (3.24e-1)" "unprognostic (2.68e-1)" DNAH3 "DKFZp434N074, DLP3, Dnahc3b, Hsadhc3" ENSG00000158486 "Dynein axonemal heavy chain 3" Q8TD57 16 20933111-21159441 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "fallopian tube: 5.1;testis: 3.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 96.6;Early spermatids: 202.5;Endometrial ciliated cells: 284.6;Ependymal cells: 459.8;Epididymal efferent duct ciliated cells: 121.7;Fallopian tube ciliated cells: 315.7;Late primary spermatocytes: 87.1;Respiratory ciliated cells: 900.1" "Cell type enriched" "Detected in many" 4 "Ciliated cells: 900.1" "Cell type enriched" "Detected in many" 57 "ependymal cell: 467.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8002 "Collecting ducts: 685323.0;Fallopian tube cells: 914984.1" "Not detected" "Not detected" "HPA056212, HPA062493" Approved "Equatorial segment,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" 1 "Mid piece, Principal piece" "Equatorial segment, Flagellar centriole" "HPA056212: , HPA062493: " "unprognostic (4.03e-1)" "unprognostic (1.09e-1)" "unprognostic (1.91e-1)" DNAH6 "Dnahc6, DNHL1, FLJ37357, HL-2" ENSG00000115423 "Dynein axonemal heavy chain 6" Q9C0G6 2 84516455-84819589 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.0;fallopian tube: 5.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1073.6;Corticotrophs: 299.0;Endometrial ciliated cells: 537.7;Ependymal cells: 1671.8;Epididymal efferent duct ciliated cells: 371.4;Fallopian tube ciliated cells: 649.1;Respiratory ciliated cells: 1137.5" "Cell type enriched" "Detected in many" 5 "Ciliated cells: 1671.8" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 779.6;ependymal cell: 1841.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Skeletal myofibers: 28879829.0" "Tissue enriched" "Detected in some" "ovary: 12834902.8" "HPA036391, HPA061401" Enhanced Approved "Plasma membrane,Primary cilium tip,Centriolar satellite,Basal body,Calyx,Connecting piece,Mid piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "Plasma membrane, Centriolar satellite, Basal body, Connecting piece, Mid piece" "Primary cilium tip, Calyx" "HPA036391: , HPA061401: " "unprognostic (2.55e-2)" "unprognostic (2.21e-1)" "unprognostic (7.02e-3)" "unprognostic (1.29e-1)" "unprognostic (2.35e-2)" "unprognostic (5.24e-2)" DNAI3 "DIC3, FLJ30067, NYD-SP29, WDR63" ENSG00000162643 "Dynein axonemal intermediate chain 3" Q8IWG1 1 84999147-85133138 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 20.6;choroid plexus: 40.0;fallopian tube: 13.6;testis: 17.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 179.5;Choroid plexus epithelial cells: 149.2;Endometrial ciliated cells: 212.6;Ependymal cells: 450.8;Epicardial cells: 138.7;Epididymal efferent duct ciliated cells: 219.1;Fallopian tube ciliated cells: 281.9;Gonadotrophs: 103.1;Late primary spermatocytes: 148.8;Melanocytes: 363.6;Respiratory ciliated cells: 285.8" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 179.5;Ciliated cells: 450.8;Pigment cells: 363.6;Spermatogenic cell types: 148.8" "Group enriched" "Detected in many" 7 "choroid plexus epithelial cell: 143.1;ependymal cell: 501.6" "Group enriched" "Detected in some" 4 "Skin Cutaneous Melanoma (TCGA): 7.8;Uterine Corpus Endometrial Carcinoma (TCGA): 6.8" "Region enhanced" "Detected in all" "choroid plexus: 49.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 3.3" "Lung - Respiratory ciliated cells, Skin - Melanocytes, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6155 "Fallopian tube cells: 615487.8" "Tissue enriched" "Detected in single" 60 "fallopian tube: 6004.7" HPA038526 Enhanced Approved "Perinuclear theca,Calyx,Connecting piece,Mid piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 50: Lymphoma - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" "Connecting piece" "Perinuclear theca, Calyx, Mid piece" "HPA038526: " "unprognostic (1.25e-2)" "unprognostic (1.66e-2)" "potential prognostic favorable (1.80e-4)" "unprognostic (2.67e-1)" "unprognostic (1.27e-1)" "unprognostic (1.26e-2)" "unprognostic (1.08e-1)" "unprognostic (1.20e-1)" "unprognostic (2.69e-2)" "unprognostic (2.45e-2)" DNAJA3 "hTid-1, TID1" ENSG00000103423 "DnaJ heat shock protein family (Hsp40) member A3" Q96EY1 16 4425805-4456775 "Essential proteins, Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 26.5;Brain inhibitory neurons: 26.4;Distal convoluted tubule cells: 27.9;Early spermatids: 36.8;Late primary spermatocytes: 43.1;Late spermatids: 32.8;Loop of henle epithelial cells: 24.5;Oligodendrocytes: 22.3;Other brain neurons: 27.9;Papillary tip epithelial cells: 24.4;Renal collecting duct intercalated cells: 29.8;Renal collecting duct principal cells: 24.1" "Cell type enhanced" "Detected in many" "Ductal cells: 29.8;Neuronal cells: 27.9;Renal nephron cells: 27.9;Spermatogenic cell types: 43.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "CAB016095, HPA040875, HPA044229" Approved Supported Vesicles,Mitochondria NA NA 33000 "Cluster 24: Non-specific - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 47 Mitochondria Vesicles "CAB016095: , HPA040875: , HPA044229: " "unprognostic (2.10e-2)" "unprognostic (7.11e-3)" "unprognostic (1.42e-2)" "unprognostic (9.34e-3)" "unprognostic (3.60e-2)" "unprognostic (1.49e-1)" "unprognostic (6.01e-2)" "unprognostic (7.60e-3)" "unprognostic (2.05e-1)" "unprognostic (2.17e-2)" "potential prognostic favorable (3.38e-5)" "unprognostic (1.26e-1)" "unprognostic (1.22e-1)" "unprognostic (9.00e-3)" "unprognostic (9.61e-3)" "unprognostic (2.57e-2)" "unprognostic (6.76e-2)" "unprognostic (3.37e-1)" "unprognostic (1.55e-1)" "unprognostic (2.76e-2)" "unprognostic (2.92e-1)" "unprognostic (4.28e-3)" "unprognostic (8.24e-3)" "unprognostic (2.35e-3)" "potential prognostic favorable (7.23e-4)" "unprognostic (3.69e-1)" "unprognostic (1.13e-1)" "unprognostic (3.38e-1)" "unprognostic (1.75e-1)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" DNAJA4 PRO1472 ENSG00000140403 "DnaJ heat shock protein family (Hsp40) member A4" Q8WW22 15 78264086-78282196 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 135.1" "Cell type enhanced" "Detected in many" "Breast lactating cells: 259.9;Early spermatids: 842.3;Epididymal efferent duct absorptive cells: 494.8;Epididymal efferent duct ciliated cells: 415.5;Late spermatids: 2211.9;Respiratory ciliated cells: 267.6" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 2211.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 6062854.4;Skeletal myofibers: 8998255.8" "Group enriched" "Detected in many" "cerebral cortex: 11275484.3;heart muscle: 27659956.3" "CAB004646, HPA041790" Uncertain Approved "Nuclear membrane,Plasma membrane,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 52: Non-specific - Cellular respiration" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 16 "Plasma membrane, Cytosol" "Nuclear membrane, Primary cilium, Centriolar satellite, Basal body" "CAB004646: , HPA041790: " "potential prognostic favorable (6.30e-4)" "unprognostic (5.98e-2)" "unprognostic (1.71e-1)" "unprognostic (1.80e-1)" "unprognostic (1.84e-1)" "unprognostic (7.85e-2)" "unprognostic (1.24e-3)" "unprognostic (5.29e-3)" "unprognostic (1.16e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (8.85e-6)" "unprognostic (7.79e-3)" "unprognostic (2.12e-3)" "unprognostic (2.11e-2)" "unprognostic (1.55e-3)" "unprognostic (5.07e-2)" "unprognostic (5.88e-2)" "unprognostic (2.26e-1)" "unprognostic (1.25e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (8.16e-4)" "unprognostic (2.80e-2)" "unprognostic (3.09e-3)" "unprognostic (6.23e-2)" "unprognostic (1.05e-1)" "unprognostic (1.72e-1)" "unprognostic (3.31e-2)" "unprognostic (8.78e-2)" "unprognostic (2.34e-1)" "unprognostic (5.87e-2)" "unprognostic (1.93e-1)" DNAJB13 "RSPH16A, TSARG6" ENSG00000187726 "DnaJ heat shock protein family (Hsp40) member B13" P59910 11 73951026-73970366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Chaperone "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 25.4;fallopian tube: 50.1;testis: 18.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 52.8;Early spermatids: 76.8;Endometrial ciliated cells: 170.5;Ependymal cells: 110.1;Epididymal efferent duct ciliated cells: 141.0;Fallopian tube ciliated cells: 273.2;Late primary spermatocytes: 91.4;Late spermatids: 80.8;Oocytes: 41.4;Respiratory ciliated cells: 137.4" "Group enriched" "Detected in many" 4 "Ciliated cells: 273.2;Spermatogenic cell types: 91.4" "Group enriched" "Detected in many" 23 "choroid plexus epithelial cell: 40.5;ependymal cell: 113.2" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 21.4;Uterine Corpus Endometrial Carcinoma (TCGA): 25.9" "Region enhanced" "Detected in all" "choroid plexus: 23.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 125354 "Fallopian tube cells: 12535350.8" "Tissue enriched" "Detected in single" 108377 "fallopian tube: 10837675.2" "HPA052465, HPA061330" Enhanced Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Mid piece,Principal piece,End piece" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 "Plasma membrane, Mid piece, Principal piece, End piece" "Nucleoli, Nucleoli rim, Mitotic chromosome, Vesicles, Primary cilium, Primary cilium tip" "HPA052465: , HPA061330: " "unprognostic (1.53e-2)" "unprognostic (4.15e-1)" "unprognostic (4.39e-2)" "unprognostic (1.99e-2)" "unprognostic (2.97e-1)" "unprognostic (4.64e-3)" "unprognostic (1.54e-1)" "unprognostic (2.75e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-1)" "unprognostic (7.84e-2)" "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (5.37e-2)" "unprognostic (6.36e-2)" "unprognostic (1.72e-1)" "unprognostic (7.12e-2)" DNAJC8 SPF31 ENSG00000126698 "DnaJ heat shock protein family (Hsp40) member C8" O75937 1 28199456-28233029 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA026275, HPA026283" Approved Enhanced "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 70 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA026275: , HPA026283: " "unprognostic (9.60e-2)" "unprognostic (2.43e-2)" "potential prognostic unfavorable (9.79e-5)" "unprognostic (2.33e-1)" "unprognostic (7.97e-2)" "unprognostic (4.00e-1)" "unprognostic (8.57e-2)" "unprognostic (7.62e-2)" "unprognostic (1.69e-1)" "unprognostic (9.45e-3)" "potential prognostic favorable (2.63e-9)" "unprognostic (3.55e-2)" "unprognostic (3.30e-2)" "validated prognostic unfavorable (3.18e-4)" "validated prognostic unfavorable (8.13e-4)" "unprognostic (1.02e-1)" "unprognostic (1.71e-2)" "unprognostic (1.28e-1)" "unprognostic (1.95e-1)" "unprognostic (1.78e-1)" "unprognostic (2.38e-1)" "unprognostic (1.04e-1)" "unprognostic (2.30e-1)" "unprognostic (4.24e-2)" "unprognostic (2.26e-1)" "unprognostic (2.53e-2)" "unprognostic (6.79e-3)" "unprognostic (1.75e-1)" "unprognostic (6.00e-2)" "unprognostic (2.50e-1)" "unprognostic (2.50e-2)" DNAL1 "1700010H15RiK, C14orf168, CILD16, MGC12435" ENSG00000119661 "Dynein axonemal light chain 1" Q4LDG9 14 73644875-73703732 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 51.0" "Cell type enhanced" "Detected in many" "Early spermatids: 306.5;Endometrial ciliated cells: 161.4;Ependymal cells: 116.2;Epididymal efferent duct ciliated cells: 138.1;Fallopian tube ciliated cells: 188.8;Late primary spermatocytes: 521.6;Respiratory ciliated cells: 231.7" "Group enriched" "Detected in many" 4 "Ciliated cells: 231.7;Spermatogenic cell types: 521.6" "Cell type enhanced" "Detected in all" "ependymal cell: 144.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 1220524.7" "Group enriched" "Detected in some" 34679 "cerebral cortex: 2782646.2;fallopian tube: 4153079.9" "HPA053129, HPA060974" Approved Approved "Nucleoplasm,Centriolar satellite,Centrosome,Basal body,Cytosol,Acrosome,Mid piece,Principal piece,End piece" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Nucleoplasm, Basal body, Cytosol, Principal piece" "Centriolar satellite, Centrosome, Acrosome, Mid piece, End piece" "HPA053129: , HPA060974: " "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "unprognostic (1.85e-1)" "unprognostic (1.28e-1)" "unprognostic (7.29e-2)" "unprognostic (5.13e-2)" "unprognostic (2.27e-1)" "unprognostic (2.20e-2)" "unprognostic (3.70e-3)" "potential prognostic unfavorable (1.04e-4)" "potential prognostic favorable (1.58e-4)" "unprognostic (1.28e-2)" "unprognostic (1.30e-3)" "potential prognostic unfavorable (2.72e-4)" "unprognostic (1.31e-1)" "unprognostic (5.33e-2)" "unprognostic (3.74e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (4.70e-1)" "potential prognostic unfavorable (6.28e-6)" "unprognostic (4.44e-2)" "unprognostic (2.80e-3)" "unprognostic (3.04e-2)" "unprognostic (1.02e-2)" "unprognostic (9.86e-2)" "unprognostic (8.00e-2)" "unprognostic (3.57e-2)" "unprognostic (1.84e-1)" "unprognostic (5.57e-2)" "unprognostic (2.30e-1)" DNAL4 "dJ327J16, PIG27" ENSG00000100246 "Dynein axonemal light chain 4" O96015 22 38778508-38794198 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in some" 6 "Late spermatids: 246.4" "Cell type enriched" "Detected in some" 58 "Spermatogenic cell types: 246.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5359 "Fallopian tube cells: 535924.4" "Group enriched" "Detected in some" 1606 "cerebral cortex: 202418.3;fallopian tube: 118807.8" HPA003647 Approved Approved "Nucleoplasm,Nucleoli,Primary cilium transition zone,Centrosome,Basal body,Cytosol,Acrosome,Equatorial segment,Perinuclear theca,Calyx,Principal piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 21: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 24 "Centrosome, Basal body, Acrosome" "Nucleoplasm, Nucleoli, Primary cilium transition zone, Cytosol, Equatorial segment, Perinuclear theca, Calyx, Principal piece" "HPA003647: " "unprognostic (3.31e-1)" "unprognostic (4.68e-2)" "unprognostic (3.51e-1)" "unprognostic (8.89e-2)" "unprognostic (3.34e-1)" "unprognostic (1.08e-1)" "unprognostic (6.74e-2)" "unprognostic (3.27e-1)" "unprognostic (1.42e-1)" "unprognostic (5.67e-2)" "potential prognostic favorable (1.68e-5)" "unprognostic (3.40e-2)" "unprognostic (3.68e-2)" "unprognostic (2.42e-3)" "unprognostic (8.40e-3)" "unprognostic (2.94e-2)" "unprognostic (2.81e-1)" "unprognostic (1.35e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-2)" "unprognostic (1.96e-1)" "unprognostic (3.99e-2)" "unprognostic (1.09e-2)" "unprognostic (2.53e-1)" "unprognostic (7.75e-2)" "unprognostic (4.67e-1)" "unprognostic (5.59e-2)" "unprognostic (4.24e-2)" "unprognostic (8.28e-2)" "unprognostic (7.43e-3)" "unprognostic (3.62e-3)" DNALI1 "dJ423B22.5, hp28, P28" ENSG00000163879 "Dynein axonemal light intermediate chain 1" O14645 1 37556919-37566857 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 75.0;fallopian tube: 51.2" "Cell type enhanced" "Detected in many" "Early spermatids: 657.8;Endometrial ciliated cells: 336.5;Epididymal efferent duct ciliated cells: 363.9;Fallopian tube ciliated cells: 391.2;Late primary spermatocytes: 514.2;Late spermatids: 1404.5;Respiratory ciliated cells: 447.7" "Group enriched" "Detected in many" 19 "Ciliated cells: 447.7;Spermatogenic cell types: 1404.5" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 70.6;ependymal cell: 177.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 8.1" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Fallopian tube cells: 11568863.9" "Tissue enriched" "Detected in some" "fallopian tube: 4058574.1" "HPA028305, HPA031633" Enhanced Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Mid piece,Principal piece,End piece" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 63 "Primary cilium, Mid piece, Principal piece, End piece" "Nucleoplasm, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA028305: , HPA031633: " "unprognostic (1.87e-2)" "unprognostic (3.31e-1)" "unprognostic (8.36e-2)" "unprognostic (3.13e-2)" "unprognostic (9.88e-2)" "unprognostic (2.69e-1)" "unprognostic (1.55e-1)" "unprognostic (3.57e-2)" "unprognostic (1.10e-1)" "validated prognostic favorable (4.56e-6)" "validated prognostic favorable (1.14e-4)" "unprognostic (5.38e-3)" "unprognostic (3.17e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (3.17e-4)" "unprognostic (2.50e-1)" "unprognostic (9.15e-2)" "unprognostic (2.64e-1)" "unprognostic (1.96e-2)" "unprognostic (1.72e-1)" "unprognostic (3.03e-2)" "unprognostic (1.47e-1)" "unprognostic (3.92e-2)" "unprognostic (2.42e-1)" "unprognostic (1.02e-1)" "unprognostic (1.76e-1)" "unprognostic (6.72e-2)" "unprognostic (1.14e-1)" "unprognostic (6.83e-2)" "unprognostic (1.62e-1)" DND1 "MGC34750, RBMS4" ENSG00000256453 "DND microRNA-mediated repression inhibitor 1" Q8IYX4 5 140670794-140673576 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 3.3;testis: 11.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 10.8;Differentiating spermatogonia: 25.4;Early primary spermatocytes: 10.5;Early spermatids: 46.8;Epicardial cells: 13.6;Oocytes: 152.0;Undifferentiated spermatogonia: 40.0" "Group enriched" "Detected in some" 7 "Oocytes: 152.0;Spermatogenic cell types: 46.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Testicular Germ Cell Tumor (TCGA): 27.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 11024 "Oocytes: 1102435.9" "Not detected" "Not detected" "HPA038443, HPA059723" Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 Nucleoplasm "Focal adhesion sites, Cytosol" "HPA038443: , HPA059723: " "unprognostic (1.75e-1)" "unprognostic (1.37e-3)" "unprognostic (9.12e-2)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (1.59e-2)" "unprognostic (2.41e-1)" DNHD1 "C11orf47, CCDC35, DHCD1, DKFZp686J0796, DNHD1L, FLJ32752, FLJ35709, FLJ46184" ENSG00000179532 "Dynein heavy chain domain 1" Q96M86 11 6497260-6593758 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 165.1;Cardiomyocytes: 300.4;Epicardial cells: 227.4;Myonuclei: 150.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 227.4;Myocytes: 300.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 18773 "Capillaries: 1877310.6" "Not detected" "Not detected" "HPA039698, HPA040267" Uncertain Supported "Mid piece,Annulus" NA No "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "Mid piece" Annulus "HPA039698: , HPA040267: " "unprognostic (1.05e-2)" "unprognostic (2.70e-1)" "unprognostic (8.04e-3)" "unprognostic (2.22e-1)" "unprognostic (2.57e-1)" "unprognostic (1.02e-1)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (5.65e-5)" "unprognostic (2.19e-1)" "unprognostic (3.06e-1)" "unprognostic (1.09e-2)" "unprognostic (2.02e-1)" "unprognostic (3.64e-1)" "unprognostic (9.11e-2)" "unprognostic (3.38e-2)" "unprognostic (4.02e-2)" "unprognostic (1.63e-2)" "unprognostic (2.10e-2)" "unprognostic (1.82e-1)" "unprognostic (2.66e-1)" "unprognostic (2.85e-1)" DNMBP "ARHGEF36, KIAA1010, Tuba" ENSG00000107554 "Dynamin binding protein" Q6XZF7 10 99875577-100009947 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Cataract, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 278.4;Ocular epithelial cells: 416.6;Urothelial cells: 493.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 493.9" "Cell type enhanced" "Detected in all" "fibroblast: 159.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 1169791.4;Microglia and Neuropil: 1172923.6;Neurons: 951052.5;T-cells: 3624036.7" "Tissue enhanced" "Detected in many" "bone marrow: 926086.8" "HPA037878, HPA058216" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Golgi apparatus,Cytosol" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 100: Stratified epithelial cells - Barrier functions" 24 "Nucleoli, Golgi apparatus, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA037878: , HPA058216: " "unprognostic (1.49e-2)" "unprognostic (2.09e-1)" "unprognostic (2.40e-2)" "unprognostic (3.49e-1)" "unprognostic (1.95e-1)" "unprognostic (2.46e-1)" "unprognostic (2.77e-3)" "unprognostic (1.58e-2)" "unprognostic (1.41e-1)" "unprognostic (2.00e-1)" "validated prognostic favorable (1.61e-5)" "validated prognostic favorable (3.17e-4)" "unprognostic (1.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.22e-2)" "unprognostic (2.74e-2)" "unprognostic (1.57e-2)" "unprognostic (7.05e-2)" "unprognostic (8.72e-2)" "unprognostic (4.06e-2)" "unprognostic (7.11e-2)" "unprognostic (2.72e-3)" "unprognostic (3.60e-1)" "unprognostic (5.21e-2)" "unprognostic (3.02e-2)" "unprognostic (2.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (4.28e-2)" "unprognostic (2.21e-2)" "potential prognostic favorable (2.12e-4)" DNMT3A ENSG00000119772 "DNA methyltransferase 3 alpha" Q9Y6K1 2 25227855-25342590 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Chromatin regulator, DNA-binding, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 233.8;Myonuclei: 261.5;Rod photoreceptor cells: 254.4" "Cell type enhanced" "Detected in all" "Myocytes: 261.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 966952.3;Neutrophils: 607909.5" "Tissue enriched" "Detected in many" "intestine: 2790311.6" "CAB009469, HPA026588" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 7: Non-specific - Transcription" 57 Nucleoplasm Vesicles "CAB009469: , HPA026588: " "potential prognostic favorable (9.16e-4)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (2.27e-1)" "unprognostic (6.48e-2)" "unprognostic (1.06e-1)" "unprognostic (8.92e-2)" "unprognostic (1.87e-1)" "unprognostic (7.16e-2)" "unprognostic (2.32e-2)" "unprognostic (8.53e-2)" "unprognostic (3.65e-2)" "unprognostic (3.73e-2)" "validated prognostic unfavorable (4.36e-6)" "validated prognostic unfavorable (7.61e-4)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (6.96e-4)" "unprognostic (1.50e-1)" "unprognostic (1.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.47e-1)" "unprognostic (2.73e-1)" "unprognostic (1.44e-2)" "unprognostic (2.00e-2)" "unprognostic (1.79e-1)" "unprognostic (8.88e-2)" "unprognostic (2.89e-1)" "unprognostic (3.80e-2)" "unprognostic (1.60e-1)" "unprognostic (1.69e-1)" "unprognostic (1.52e-1)" DNMT3B ENSG00000088305 "DNA methyltransferase 3 beta" Q9UBC3 20 32762385-32809359 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Activator, DNA-binding, Methyltransferase, Repressor, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 5.8;testis: 5.7" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 46.6;Megakaryocyte progenitors: 55.9;Megakaryocyte-Erythroid progenitors: 26.9;Migrating cytotrophoblasts: 18.4;Pancreatic acinar cells: 21.3;Retinal amacrine cells: 19.2;Sertoli cells: 61.9;Thymocytes: 18.6" "Cell type enhanced" "Detected in many" "Megakaryocytes: 55.9;Reproductive supporting cells: 61.9;Stem cells: 46.6" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 18 "Testicular Germ Cell Tumor (TCGA): 242.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 6 "testis cancer: 122.2" "Skeletal muscle - Fibroblasts, Stomach - Mitotic cells (Stomach)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001595, HPA001803, CAB069896" Enhanced Supported Nucleoplasm NA Yes "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 40 Nucleoplasm "CAB069896: , HPA001595: , HPA001803: " "unprognostic (1.98e-1)" "unprognostic (1.67e-2)" "unprognostic (5.85e-2)" "unprognostic (3.88e-3)" "unprognostic (2.49e-2)" "unprognostic (3.86e-2)" "unprognostic (4.01e-1)" "unprognostic (1.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (4.16e-6)" "unprognostic (1.20e-3)" "unprognostic (2.80e-2)" "unprognostic (5.04e-2)" "unprognostic (7.76e-3)" "unprognostic (6.66e-2)" "unprognostic (5.99e-2)" "unprognostic (4.01e-3)" "unprognostic (1.89e-1)" "unprognostic (2.67e-1)" "unprognostic (3.62e-2)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (1.41e-2)" "unprognostic (6.30e-2)" "unprognostic (1.00e-2)" "unprognostic (3.63e-1)" "unprognostic (1.35e-1)" "unprognostic (2.19e-1)" "unprognostic (7.90e-2)" DNPH1 "C6orf108, dJ330M21.3, rcl" ENSG00000112667 "2'-deoxynucleoside 5'-phosphate N-hydrolase 1" O43598 6 43225629-43229481 "Predicted intracellular proteins" "Nucleotide metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 289.4;Enterocytes: 713.3;Epididymal efferent duct absorptive cells: 371.1;Epididymal efferent duct ciliated cells: 410.5;Fallopian tube ciliated cells: 391.5;Hepatocytes: 270.4;Hofbauer cells: 432.6;Respiratory ciliated cells: 295.6" "Cell type enhanced" "Detected in many" "Enterocytes: 713.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 1150448.3" "Tissue enhanced" "Detected in all" "kidney: 208492073.1" "HPA029675, HPA029676" Enhanced Approved Nucleoplasm,Cytosol No No 290000 "Cluster 33: Non-specific - ATP binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 1: Enterocytes - Absorption and Digestion" 5 Nucleoplasm Cytosol "HPA029675: , HPA029676: " "unprognostic (7.89e-2)" "unprognostic (1.99e-2)" "unprognostic (2.92e-1)" "unprognostic (5.26e-2)" "unprognostic (3.49e-2)" "unprognostic (1.74e-1)" "unprognostic (2.03e-1)" "unprognostic (5.86e-2)" "unprognostic (6.35e-2)" "unprognostic (4.58e-2)" "unprognostic (1.18e-1)" "unprognostic (2.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.43e-2)" "unprognostic (2.98e-1)" "unprognostic (1.91e-2)" "unprognostic (4.05e-2)" "unprognostic (7.41e-2)" "unprognostic (3.29e-3)" "unprognostic (4.05e-1)" "unprognostic (9.85e-2)" "unprognostic (1.25e-2)" "unprognostic (8.61e-2)" "unprognostic (8.53e-2)" "unprognostic (2.02e-1)" "unprognostic (2.44e-3)" "unprognostic (1.02e-2)" DNTTIP1 "C20orf167, dJ447F3.4, Tdif1" ENSG00000101457 "Deoxynucleotidyltransferase terminal interacting protein 1" Q9H147 20 45791954-45811427 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 160.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 125.6" "Group enriched" "Detected in all" 6 "dendritic cells: 43.4;granulocytes: 125.6;monocytes: 51.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 907447.3;Granulosa cells: 695323.7;Keratinocytes: 473943.5;Neutrophils: 1855753.3;T-cells: 725248.8" "Group enriched" "Detected in many" "bone marrow: 4308537.8;intestine: 5907355.1" HPA045496 Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 35 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA045496: " "unprognostic (1.17e-1)" "unprognostic (2.80e-1)" "unprognostic (2.29e-1)" "unprognostic (3.80e-1)" "unprognostic (4.45e-2)" "unprognostic (2.12e-1)" "unprognostic (7.43e-2)" "unprognostic (3.45e-1)" "unprognostic (1.07e-2)" "unprognostic (2.08e-1)" "validated prognostic unfavorable (4.26e-8)" "validated prognostic unfavorable (5.82e-7)" "unprognostic (2.20e-1)" "validated prognostic unfavorable (8.76e-6)" "validated prognostic unfavorable (1.04e-4)" "unprognostic (5.29e-2)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (6.74e-2)" "unprognostic (1.30e-1)" "unprognostic (2.97e-1)" "unprognostic (8.90e-2)" "unprognostic (1.43e-2)" "unprognostic (1.31e-2)" "unprognostic (5.38e-2)" "unprognostic (1.04e-1)" "unprognostic (9.92e-2)" "unprognostic (3.01e-1)" "unprognostic (3.64e-1)" "unprognostic (4.98e-1)" "unprognostic (5.89e-2)" "unprognostic (8.16e-2)" DNTTIP2 "ERBP, HSU15552, TdIF2" ENSG00000067334 "Deoxynucleotidyltransferase terminal interacting protein 2" Q5QJE6 1 93866284-93879918 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 41.3" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "fallopian tube: 2159350.8;intestine: 4120749.5;lymphoid tissue: 2239361.4;Stomach: 5045814.9" "HPA044502, HPA053707" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 21 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA044502: , HPA053707: " "unprognostic (2.02e-1)" "unprognostic (2.90e-1)" "unprognostic (8.38e-2)" "unprognostic (2.12e-1)" "unprognostic (2.38e-2)" "unprognostic (2.62e-2)" "unprognostic (2.91e-2)" "unprognostic (4.45e-1)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (9.57e-6)" "unprognostic (3.01e-3)" "unprognostic (1.21e-3)" "unprognostic (1.57e-3)" "potential prognostic unfavorable (1.76e-7)" "unprognostic (2.66e-2)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (7.42e-3)" "unprognostic (3.34e-2)" "unprognostic (5.54e-2)" "unprognostic (5.99e-2)" "unprognostic (2.88e-1)" "unprognostic (3.09e-2)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (9.66e-3)" "unprognostic (9.84e-3)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (3.41e-1)" DOCK5 FLJ21034 ENSG00000147459 "Dedicator of cytokinesis 5" Q9H7D0 8 25184689-25418082 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 3294.7;Oligodendrocytes: 1106.9;Podocytes: 2267.7;Thyrotrophs: 748.4" "Cell type enhanced" "Detected in many" "Neutrophils: 3294.7;Renal nephron cells: 2267.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 920.8;oligodendrocyte: 1478.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 30.7" "Lineage enriched" "Detected in many" 4 "granulocytes: 30.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 10722202.4" "Low tissue specificity" "Detected in many" "HPA017719, HPA056837" Approved Enhanced Cytosol No No "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 29 Cytosol "HPA017719: , HPA056837: " "unprognostic (1.24e-1)" "unprognostic (3.27e-1)" "unprognostic (4.79e-2)" "unprognostic (1.94e-2)" "unprognostic (1.99e-2)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" "unprognostic (3.01e-3)" "unprognostic (9.02e-2)" "unprognostic (9.69e-2)" "unprognostic (3.82e-2)" "unprognostic (3.12e-2)" "unprognostic (1.05e-2)" "potential prognostic unfavorable (4.36e-4)" "unprognostic (2.29e-1)" "unprognostic (2.01e-2)" "unprognostic (1.46e-1)" "unprognostic (1.15e-1)" "unprognostic (8.82e-2)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (1.35e-3)" "unprognostic (2.02e-1)" "unprognostic (5.84e-2)" "unprognostic (3.87e-2)" "unprognostic (4.65e-2)" "unprognostic (2.97e-1)" "unprognostic (2.55e-1)" "unprognostic (1.29e-3)" "unprognostic (3.13e-2)" DOHH "HLRC1, MGC4293" ENSG00000129932 "Deoxyhypusine hydroxylase" Q9BU89 19 3490821-3500674 "Enzymes, Predicted intracellular proteins" "Hypusine biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.7" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 50.3;Esophageal suprabasal cells: 47.8" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "oligodendrocyte: 48.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 1952291.9" "Low tissue specificity" "Detected in all" "HPA041953, HPA076271" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 2 Cytosol "Nucleoplasm, Nucleoli" "HPA041953: , HPA076271: " "unprognostic (9.00e-2)" "unprognostic (1.36e-1)" "unprognostic (5.07e-2)" "unprognostic (2.57e-1)" "unprognostic (6.03e-2)" "unprognostic (1.72e-1)" "unprognostic (4.47e-1)" "unprognostic (4.10e-1)" "unprognostic (2.34e-3)" "unprognostic (2.35e-1)" "unprognostic (1.93e-2)" "unprognostic (1.23e-1)" "unprognostic (9.97e-2)" "unprognostic (1.62e-2)" "unprognostic (2.29e-2)" "unprognostic (2.11e-1)" "unprognostic (3.03e-2)" "unprognostic (5.89e-2)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.29e-1)" "unprognostic (4.08e-3)" "unprognostic (3.08e-1)" "unprognostic (1.16e-2)" "unprognostic (1.15e-1)" "unprognostic (1.02e-3)" "unprognostic (2.58e-1)" "unprognostic (1.95e-2)" "unprognostic (4.88e-1)" "unprognostic (1.17e-1)" "unprognostic (3.10e-3)" DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 88.4;lymphoid tissue: 83.8" "Group enriched" "Detected in many" 4 "Neutrophil progenitors: 173.8;Neutrophils: 585.6" "Cell type enriched" "Detected in many" 6 "Neutrophils: 585.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 37.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 134.3" "Group enriched" "Detected in many" 6 "B-cells: 37.3;granulocytes: 134.3;monocytes: 78.1" "Group enriched" "Detected in all" 6 "Leukemia: 72.6;lymphoma: 95.9;Myeloma: 24.7" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "B-cells: 16247637.5;Macrophages: 8708554.1;Neutrophils: 11255666.8;T-cells: 6337818.1" "Group enriched" "Detected in many" "bone marrow: 5631235.1;lung: 1967159.2;lymphoid tissue: 6753440.6" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 130000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: " "unprognostic (2.77e-3)" "unprognostic (7.49e-2)" "unprognostic (6.01e-2)" "unprognostic (2.17e-1)" "unprognostic (7.50e-2)" "unprognostic (9.46e-2)" "unprognostic (2.30e-3)" "unprognostic (3.60e-1)" "unprognostic (1.56e-3)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (8.04e-5)" "unprognostic (6.49e-2)" "unprognostic (1.71e-1)" "unprognostic (2.12e-2)" "unprognostic (2.94e-2)" "unprognostic (4.48e-2)" "unprognostic (7.96e-2)" "unprognostic (1.87e-1)" "unprognostic (1.59e-1)" "unprognostic (3.20e-1)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.27e-2)" "unprognostic (7.14e-2)" "unprognostic (2.44e-2)" "unprognostic (2.27e-1)" "unprognostic (2.04e-2)" "unprognostic (1.74e-1)" "unprognostic (1.06e-1)" "unprognostic (2.65e-1)" "unprognostic (6.82e-2)" DOK4 FLJ10488 ENSG00000125170 "Docking protein 4" Q8TEW6 16 57471922-57487327 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 94.8;Enterocytes: 99.4;Esophageal apical cells: 97.3;Esophageal suprabasal cells: 46.0;Foveolar cells: 53.5" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 97.3;Enterocytes: 99.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Neuroblastoma: 186.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1516 "Proximal tubules: 151598.6" "Not detected" "Not detected" "HPA008348, HPA055849" Supported Approved Cytosol NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 28 Cytosol "HPA008348: , HPA055849: " "unprognostic (8.59e-3)" "unprognostic (5.36e-3)" "unprognostic (3.09e-1)" "unprognostic (1.81e-2)" "unprognostic (1.00e-1)" "unprognostic (9.48e-2)" "unprognostic (1.52e-1)" "unprognostic (5.29e-3)" "unprognostic (8.53e-2)" "unprognostic (2.59e-1)" "unprognostic (1.09e-3)" "unprognostic (1.07e-1)" "potential prognostic favorable (7.86e-5)" "unprognostic (7.08e-2)" "unprognostic (2.90e-2)" "unprognostic (1.61e-2)" "unprognostic (1.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.92e-1)" "unprognostic (1.94e-2)" "unprognostic (2.81e-2)" "unprognostic (1.23e-2)" "unprognostic (1.01e-1)" "unprognostic (4.51e-2)" "unprognostic (2.03e-1)" "unprognostic (5.08e-3)" "unprognostic (4.83e-2)" "unprognostic (3.21e-2)" "unprognostic (1.79e-1)" "unprognostic (1.74e-2)" "unprognostic (2.17e-1)" DOK7 "C4orf25, Dok-7, FLJ33718, FLJ39137" ENSG00000175920 "Docking protein 7" Q18PE1 4 3463306-3501473 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 42.8;skeletal muscle: 31.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16.4;Choroid plexus epithelial cells: 30.8;Epicardial cells: 22.7;Epididymal principal cells: 19.2;Gonadotrophs: 53.9;Lactotrophs: 33.1;Myonuclei: 32.8;Sertoli cells: 18.7;Somatotrophs: 35.1;Thymic myoid cells: 23.1;Thyrotrophs: 25.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 30.8;Myocytes: 32.8;Pituitary endocrine cells: 53.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 37.5" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 23.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "memory B-cell: 3.4;naive B-cell: 2.3;NK-cell: 1.9" "Group enriched" "Detected in many" 16 "B-cells: 3.4;NK-cells: 1.9" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Capillaries: 87399.1;Fallopian tube cells: 334367.8" "Tissue enriched" "Detected in single" 72 "fallopian tube: 7159.6" "HPA059449, HPA062780" Approved Enhanced Nucleoplasm,Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 Nucleoplasm Mitochondria "HPA059449: , HPA062780: " "unprognostic (5.25e-2)" "unprognostic (1.04e-3)" "unprognostic (5.70e-2)" "unprognostic (1.82e-1)" "unprognostic (9.91e-2)" "unprognostic (1.36e-2)" "unprognostic (3.09e-2)" "unprognostic (1.82e-2)" "unprognostic (2.63e-3)" "unprognostic (2.05e-2)" "unprognostic (7.00e-3)" "unprognostic (1.08e-1)" "unprognostic (3.48e-3)" "unprognostic (1.37e-1)" "unprognostic (1.60e-1)" "unprognostic (1.92e-1)" "unprognostic (8.72e-2)" "unprognostic (4.68e-3)" "unprognostic (1.23e-1)" "unprognostic (6.08e-2)" "unprognostic (4.37e-3)" "unprognostic (6.21e-2)" "potential prognostic favorable (5.11e-4)" DOLK "DK1, KIAA1094, TMEM15" ENSG00000175283 "Dolichol kinase" Q9UPQ8 9 128945530-128947603 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 30.5;Late primary spermatocytes: 32.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Neurons: 240103.3;Pancreas epithelial cells: 743266.5" "Not detected" "Not detected" "HPA066767, HPA068706" Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 27 "Nucleoplasm, Nucleoli" Cytosol "HPA066767: , HPA068706: " "unprognostic (1.63e-3)" "unprognostic (8.14e-3)" "unprognostic (8.77e-2)" "unprognostic (3.72e-2)" "unprognostic (4.66e-1)" "unprognostic (1.97e-2)" "unprognostic (1.72e-1)" "unprognostic (2.31e-1)" "unprognostic (9.78e-3)" "unprognostic (2.24e-2)" "potential prognostic favorable (3.74e-4)" "unprognostic (1.10e-1)" "unprognostic (2.11e-2)" "unprognostic (1.09e-2)" "unprognostic (1.93e-2)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (2.32e-1)" "unprognostic (3.08e-2)" "unprognostic (1.99e-1)" "unprognostic (2.68e-1)" "unprognostic (1.10e-2)" "unprognostic (9.15e-2)" "unprognostic (7.87e-2)" "unprognostic (2.61e-1)" "unprognostic (9.47e-2)" "unprognostic (3.12e-1)" "unprognostic (1.95e-1)" "unprognostic (2.37e-1)" "unprognostic (3.97e-3)" "potential prognostic favorable (5.47e-5)" DOP1B "C21orf5, DOPEY2, KIAA0933" ENSG00000142197 "DOP1 leucine zipper like protein B" Q9Y3R5 21 36156782-36294274 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 24.1" "Cell type enhanced" "Detected in many" "Foveolar cells: 182.8;Goblet cells: 250.1;Neutrophil progenitors: 418.9;Prostatic glandular cells: 194.5" "Cell type enhanced" "Detected in all" "Neutrophils: 418.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Large ducts: 22944105.4;Neutrophils: 18164857.9" "Tissue enhanced" "Detected in many" "salivary gland: 10350199.6" HPA072065 Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 23: B-cells - Immunoglobulins" "Cluster 76: Non-specific - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Nucleoplasm Mitochondria "HPA072065: " "unprognostic (3.10e-1)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (3.77e-1)" "unprognostic (7.23e-2)" "unprognostic (2.80e-2)" "unprognostic (1.75e-1)" "unprognostic (1.73e-1)" "unprognostic (9.38e-2)" "unprognostic (4.10e-1)" "potential prognostic favorable (1.60e-4)" "unprognostic (1.08e-2)" "unprognostic (1.65e-1)" "unprognostic (9.57e-3)" "unprognostic (2.96e-1)" "unprognostic (2.42e-2)" "unprognostic (1.48e-2)" "unprognostic (1.53e-1)" "unprognostic (8.15e-2)" "unprognostic (2.44e-1)" "unprognostic (5.89e-2)" "unprognostic (3.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.46e-2)" "unprognostic (3.99e-2)" "unprognostic (1.64e-1)" "unprognostic (1.41e-2)" "unprognostic (3.44e-2)" "unprognostic (3.20e-1)" "unprognostic (2.50e-2)" DPH5 CGI-30 ENSG00000117543 "Diphthamide biosynthesis 5" Q9H2P9 1 100989623-101026088 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 132.7" "Cell type enhanced" "Detected in many" "Myocytes: 132.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 3409279.3" "Low tissue specificity" "Detected in many" "HPA046439, HPA076234" Approved Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 25: Non-specific - Ribosome" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Golgi apparatus" Nucleoli "HPA046439: , HPA076234: " "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.03e-1)" "unprognostic (3.98e-1)" "unprognostic (3.77e-2)" "unprognostic (1.24e-2)" "unprognostic (6.96e-2)" "unprognostic (1.56e-2)" "unprognostic (1.79e-3)" "unprognostic (6.70e-2)" "unprognostic (5.96e-2)" "unprognostic (1.01e-2)" "unprognostic (8.18e-2)" "unprognostic (7.96e-2)" "unprognostic (2.16e-3)" "unprognostic (8.38e-3)" "unprognostic (7.19e-2)" "unprognostic (8.60e-2)" "potential prognostic favorable (6.16e-4)" "unprognostic (3.12e-1)" "unprognostic (6.13e-2)" "unprognostic (1.37e-1)" "unprognostic (1.19e-2)" "unprognostic (5.59e-2)" "unprognostic (2.09e-3)" "potential prognostic favorable (7.72e-4)" "unprognostic (1.01e-1)" "unprognostic (3.83e-2)" "unprognostic (1.15e-2)" "unprognostic (2.71e-1)" "unprognostic (2.69e-1)" "unprognostic (1.82e-2)" DPH7 "C9orf112, FLJ90634, RRT2, WDR85" ENSG00000148399 "Diphthamide biosynthesis 7" Q9BTV6 9 137554444-137578925 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early primary spermatocytes: 289.2" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 289.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1865 "Granulosa cells: 186538.5" "Not detected" "Not detected" HPA022911 Uncertain Approved "Nuclear bodies" Yes No "Cluster 46: Basophils - Proteolysis" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 3: Early primary spermatocytes - Early meiosis" 7 "Nuclear bodies" "HPA022911: " "unprognostic (4.41e-3)" "unprognostic (4.61e-3)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (3.10e-1)" "unprognostic (6.12e-2)" "potential prognostic favorable (2.37e-5)" "unprognostic (5.89e-2)" "unprognostic (2.77e-1)" "unprognostic (2.15e-2)" "unprognostic (6.47e-3)" "unprognostic (4.77e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (7.07e-2)" "unprognostic (1.75e-1)" "unprognostic (3.40e-1)" "unprognostic (1.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.14e-2)" "unprognostic (2.22e-2)" "unprognostic (2.37e-3)" "unprognostic (5.92e-2)" "potential prognostic favorable (3.46e-4)" "unprognostic (6.85e-3)" "unprognostic (7.78e-2)" "unprognostic (2.08e-2)" "unprognostic (9.41e-2)" "unprognostic (9.85e-2)" "unprognostic (4.27e-1)" DPP3 ENSG00000254986 "Dipeptidyl peptidase 3" Q9NY33 11 66480013-66509657 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 18.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Kidney - Macrophages, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA035780, HPA035781" Approved Supported Cytosol NA NA 4900000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 17: Intestine - Digestion" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 5 Cytosol "HPA035780: , HPA035781: " "unprognostic (1.50e-3)" "unprognostic (3.17e-2)" "unprognostic (3.61e-1)" "unprognostic (2.07e-2)" "unprognostic (2.17e-3)" "unprognostic (7.26e-3)" "unprognostic (3.05e-1)" "unprognostic (2.41e-1)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (3.93e-2)" "unprognostic (2.05e-3)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (4.40e-4)" "unprognostic (2.07e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (2.73e-2)" "unprognostic (2.24e-1)" "unprognostic (2.47e-1)" "unprognostic (3.02e-1)" "unprognostic (2.33e-3)" "unprognostic (7.48e-2)" "unprognostic (4.84e-1)" "unprognostic (4.42e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (4.05e-3)" "unprognostic (7.97e-2)" "unprognostic (2.80e-2)" "unprognostic (1.46e-1)" DPPA4 FLJ10713 ENSG00000121570 "Developmental pluripotency associated 4" Q7L190 3 109326144-109337546 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.5;lymphoid tissue: 11.6;testis: 3.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 30.7;Extravillous trophoblasts: 21.7;Hematopoietic stem cells: 139.7;Innate lymphoid cells: 22.0;Megakaryocyte progenitors: 82.4;Megakaryocyte-Erythroid progenitors: 64.9;Megakaryocytes: 37.1;Migrating cytotrophoblasts: 18.1;pDCs: 26.4;Pituitary stem cells: 28.5;Thymocytes: 52.5;Undifferentiated spermatogonia: 29.5" "Cell type enhanced" "Detected in some" "Megakaryocytes: 82.4;Stem cells: 139.7;T-cells: 52.5" "Cell type enhanced" "Detected in some" "pericyte: 2.2;vascular associated smooth muscle cell: 1.2" "Cancer enriched" "Detected in single" 266 "Testicular Germ Cell Tumor (TCGA): 123.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 7.5" "Lineage enriched" "Detected in single" 12 "dendritic cells: 7.5" "Cancer enriched" "Detected in some" 15 "testis cancer: 113.1" "Liver - Hepatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 711 "Alveolar cell types: 71141.8" "Not detected" "Not detected" "CAB020678, HPA035249, HPA035250" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome,Cytosol" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Testis cancer - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 33 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Cytosol" "CAB020678: , HPA035249: , HPA035250: " "unprognostic (1.26e-2)" "unprognostic (3.31e-2)" DPY19L2 "FLJ32949, SPATA34" ENSG00000177990 "Dpy-19 like 2" Q6NUT2 12 63558913-63668939 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 78.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 519.9;Distal convoluted tubule cells: 234.2;Ependymal cells: 176.5;Late spermatids: 174.3;Oligodendrocyte progenitor cells: 161.4;Pituitary stem cells: 192.8;Renal collecting duct intercalated cells: 335.1;Renal connecting tubule cells: 455.5;Somatotrophs: 163.2" "Cell type enhanced" "Detected in many" "Ductal cells: 455.5;Myocytes: 519.9;Renal nephron cells: 234.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.0" "Lineage enriched" "Detected in single" 5 "T-cells: 1.0" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA071264, HPA078305" Enhanced Approved Nucleoplasm,Mitochondria Yes No "Cluster 24: Non-specific - Transcription" "Cluster 35: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Mitochondria Nucleoplasm "HPA071264: , HPA078305: " "unprognostic (8.04e-2)" "unprognostic (3.34e-1)" "unprognostic (8.70e-2)" "unprognostic (6.15e-2)" "unprognostic (1.28e-1)" "unprognostic (4.73e-1)" "unprognostic (8.12e-2)" "unprognostic (1.01e-3)" "unprognostic (1.54e-2)" "unprognostic (4.16e-2)" "unprognostic (1.36e-1)" "unprognostic (1.23e-2)" "potential prognostic favorable (7.31e-4)" "unprognostic (3.66e-3)" "unprognostic (1.45e-1)" "unprognostic (1.92e-2)" "unprognostic (2.79e-1)" "unprognostic (2.98e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (4.42e-4)" "potential prognostic unfavorable (7.63e-4)" DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 231.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 319.2;Kupffer cells: 326.9;Oligodendrocytes: 588.8;Other brain neurons: 352.3;Retinal amacrine cells: 317.3;Retinal ganglion cells: 367.0" "Cell type enhanced" "Detected in all" "Glial cells: 588.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 215.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 49.0;plasmacytoid DC: 42.3" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 3406009518.8;Microglia and Neuropil: 3264682921.7;Neurons: 1674641374.2" "Tissue enriched" "Detected in all" "cerebral cortex: 3260688529.3" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Cytosol" Yes NA 2500000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 38 "Microtubules, Cytosol" "Plasma membrane, Cytokinetic bridge, Mitotic spindle, Primary cilium" "CAB018719: , HPA002381: " "unprognostic (1.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.20e-2)" "unprognostic (1.08e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (1.23e-1)" "unprognostic (3.09e-2)" "unprognostic (2.27e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (6.01e-6)" "unprognostic (8.88e-3)" "unprognostic (3.45e-2)" "unprognostic (8.42e-2)" "unprognostic (4.37e-2)" "unprognostic (4.32e-3)" "unprognostic (1.28e-1)" "unprognostic (5.66e-3)" "unprognostic (2.36e-1)" "unprognostic (2.30e-1)" "unprognostic (1.12e-3)" "unprognostic (3.32e-2)" "unprognostic (3.96e-2)" "unprognostic (6.48e-2)" "unprognostic (3.15e-1)" "unprognostic (1.06e-1)" "unprognostic (2.08e-1)" "unprognostic (2.44e-2)" "unprognostic (2.75e-1)" "unprognostic (3.59e-3)" "unprognostic (5.31e-2)" DPYSL3 "CRMP4, DRP-3, ULIP" ENSG00000113657 "Dihydropyrimidinase like 3" Q14195 5 147390808-147510068 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1140.6;Ependymal cells: 416.4;Fibro-adipogenic progenitors: 261.0;Granulosa cells: 449.3;Ovarian stromal cells: 260.3;Peritubular myoid cells: 329.3;Prostatic glandular cells: 233.5;Rod photoreceptor cells: 526.0;Smooth muscle cells: 351.1;Tuft cells: 564.9" "Cell type enhanced" "Detected in many" "Neuronal cells: 1140.6;Reproductive supporting cells: 449.3;Secretory gland support: 564.9" "Cell type enhanced" "Detected in many" "astrocyte: 336.9;ependymal cell: 469.3" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 228.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 261141150.0" "Low tissue specificity" "Detected in all" HPA010948 Approved Approved Cytosol NA NA 680000 "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 79: Photoreceptor cells - Phototransduction" 9 Cytosol "HPA010948: " "unprognostic (4.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.26e-2)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (1.35e-1)" "unprognostic (8.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.34e-1)" "unprognostic (2.14e-2)" "unprognostic (1.14e-2)" "unprognostic (2.43e-2)" "potential prognostic unfavorable (6.69e-6)" "unprognostic (7.43e-2)" "unprognostic (3.74e-2)" "unprognostic (8.71e-2)" "unprognostic (1.10e-2)" "unprognostic (4.49e-1)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (1.47e-1)" "unprognostic (1.43e-1)" "unprognostic (5.02e-3)" "unprognostic (3.14e-2)" "unprognostic (1.18e-1)" "unprognostic (9.15e-3)" "unprognostic (2.09e-1)" "unprognostic (8.28e-2)" "unprognostic (1.45e-1)" DRG1 NEDD3 ENSG00000185721 "Developmentally regulated GTP binding protein 1" Q9Y295 22 31399604-31530634 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Hydrolase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 149.8" "Group enriched" "Detected in all" 4 "Early spermatids: 703.5;Late primary spermatocytes: 1074.6;Late spermatids: 871.0;Oocytes: 419.1" "Group enriched" "Detected in all" 4 "Oocytes: 419.1;Spermatogenic cell types: 1074.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA001218 Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No 17000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 241 "Nucleoplasm, Nuclear bodies" Cytosol "HPA001218: " "unprognostic (7.57e-3)" "unprognostic (1.86e-2)" "unprognostic (2.18e-1)" "unprognostic (2.08e-3)" "unprognostic (5.39e-3)" "unprognostic (1.37e-2)" "unprognostic (5.82e-2)" "unprognostic (1.99e-1)" "unprognostic (4.12e-3)" "unprognostic (8.19e-2)" "validated prognostic favorable (2.12e-8)" "validated prognostic favorable (7.38e-4)" "unprognostic (4.05e-1)" "validated prognostic unfavorable (3.41e-5)" "validated prognostic unfavorable (8.93e-7)" "unprognostic (5.21e-3)" "unprognostic (1.95e-2)" "unprognostic (4.57e-2)" "unprognostic (2.92e-3)" "unprognostic (5.66e-3)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (3.68e-4)" "unprognostic (8.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.44e-2)" "unprognostic (6.86e-2)" "unprognostic (1.92e-1)" "unprognostic (2.59e-1)" "unprognostic (2.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.36e-1)" DRG2 ENSG00000108591 "Developmentally regulated GTP binding protein 2" P55039 17 18087892-18107970 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA007716 Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 14 "Vesicles, Cytosol" Nucleoplasm "HPA007716: " "unprognostic (3.87e-2)" "unprognostic (6.55e-2)" "unprognostic (6.12e-2)" "unprognostic (1.31e-1)" "unprognostic (1.04e-1)" "unprognostic (2.75e-1)" "validated prognostic unfavorable (3.59e-4)" "validated prognostic unfavorable (1.14e-4)" "unprognostic (4.46e-3)" "unprognostic (1.07e-1)" "potential prognostic favorable (8.73e-4)" "unprognostic (1.34e-1)" "unprognostic (6.19e-2)" "unprognostic (2.73e-3)" "unprognostic (2.33e-1)" "unprognostic (2.81e-2)" "unprognostic (1.17e-1)" "unprognostic (3.14e-2)" "unprognostic (8.65e-3)" "unprognostic (2.43e-1)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" "unprognostic (1.02e-2)" "unprognostic (4.17e-2)" "unprognostic (1.24e-1)" "unprognostic (8.53e-2)" "unprognostic (6.48e-2)" "unprognostic (1.01e-1)" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.14e-1)" DRICH1 C22orf43 ENSG00000189269 "Aspartate rich 1" Q6PGQ1 22 23608452-23632321 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 16.0;testis: 44.0" "Group enriched" "Detected in many" 7 "Early spermatids: 762.0;Late spermatids: 1462.2" "Cell type enriched" "Detected in many" 38 "Spermatogenic cell types: 1462.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA020446 Approved Nucleoplasm,Nucleoli No No "Cluster 22: Epididymis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 5 "Nucleoplasm, Nucleoli" "HPA020446: " "unprognostic (4.28e-2)" "unprognostic (4.68e-2)" "unprognostic (2.12e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-2)" "unprognostic (4.36e-2)" "unprognostic (4.18e-1)" "unprognostic (1.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.13e-2)" DSCAM "CHD2-42, CHD2-52" ENSG00000171587 "DS cell adhesion molecule" O60469 21 40010999-40847158 "Plasma proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 6.8;pituitary gland: 3.9;retina: 1.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 941.8;Brain inhibitory neurons: 1013.5;Lactotrophs: 2491.5;Microglia: 1230.2;Oligodendrocyte progenitor cells: 7951.4;Oligodendrocytes: 1297.6;Other brain neurons: 1355.6;Pituitary stem cells: 5253.1;Retinal amacrine cells: 1189.7;Retinal bipolar cells: 884.1;Retinal ganglion cells: 3109.5;Somatotrophs: 1575.4;Thyrotrophs: 2228.7" "Group enriched" "Detected in many" 12 "Glial cells: 7951.4;Neuronal cells: 3109.5;Pituitary endocrine cells: 2491.5;Stem cells: 5253.1" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 6349.4;oligodendrocyte precursor cell: 9545.4" "Cancer enriched" "Detected in single" 15 "Glioblastoma Multiforme (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 68 "Oocytes: 6801.9" "Tissue enriched" "Detected in single" 779 "intestine: 77853.3" "HPA019324, HPA057493" Enhanced Approved "Golgi apparatus,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 3 "Golgi apparatus" Cytosol "HPA019324: , HPA057493: " "unprognostic (1.04e-1)" "unprognostic (2.05e-3)" DSN1 "C20orf172, dJ469A13.2, hKNL-3, KNL3, MIS13" ENSG00000149636 "DSN1 component of MIS12 kinetochore complex" Q9H410 20 36751791-36773818 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 87.2;Differentiating spermatogonia: 81.1;Early primary spermatocytes: 147.5;Migrating cytotrophoblasts: 72.6;Oocytes: 101.3;Syncytiotrophoblasts: 90.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 147.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "bone marrow: 358366.2;lymphoid tissue: 395451.8" "HPA002813, HPA030627" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Kinetochore,Cytosol" Yes Yes "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 51 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies, Kinetochore, Cytosol" "HPA002813: , HPA030627: " "unprognostic (1.07e-1)" "unprognostic (2.61e-2)" "unprognostic (4.09e-2)" "unprognostic (2.95e-2)" "unprognostic (3.98e-1)" "unprognostic (3.23e-2)" "unprognostic (2.26e-2)" "unprognostic (2.30e-1)" "unprognostic (2.90e-2)" "unprognostic (1.28e-2)" "unprognostic (3.39e-3)" "unprognostic (3.53e-2)" "unprognostic (2.14e-1)" "validated prognostic unfavorable (2.95e-4)" "validated prognostic unfavorable (1.77e-5)" "unprognostic (8.51e-2)" "unprognostic (1.29e-2)" "unprognostic (9.56e-2)" "unprognostic (1.73e-1)" "unprognostic (1.18e-1)" "unprognostic (4.48e-1)" "unprognostic (1.56e-2)" "unprognostic (1.94e-3)" "unprognostic (6.13e-2)" "unprognostic (1.18e-2)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (1.60e-2)" "unprognostic (2.08e-1)" "unprognostic (6.78e-2)" "unprognostic (3.25e-2)" DTL "CDT2, DCAF2, L2DTL, RAMP" ENSG00000143476 "Denticleless E3 ubiquitin protein ligase homolog" Q9NZJ0 1 212035553-212107400 "Essential proteins, Predicted intracellular proteins" "Biological rhythms, DNA damage, DNA replication, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 13.8;intestine: 4.5;lymphoid tissue: 13.2;placenta: 3.7;testis: 12.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 54.5;Early primary spermatocytes: 78.0;Erythrocyte progenitors: 141.9;Extravillous trophoblasts: 38.6;Late primary spermatocytes: 59.5;Megakaryocyte progenitors: 117.8;Megakaryocyte-Erythroid progenitors: 49.9;Migrating cytotrophoblasts: 42.6;Monocyte progenitors: 102.1;Neutrophil progenitors: 77.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 141.9;Megakaryocytes: 117.8;Mononuclear phagocytes: 102.1;Neutrophils: 77.7;Spermatogenic cell types: 78.0" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 2.0" "Lineage enriched" "Detected in single" 8 "T-cells: 2.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 10144 "Granulosa cells: 1014440.9" "Not detected" "Not detected" "HPA028016, HPA032023, HPA032031" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 36 Nucleoplasm "Nucleoli, Cytosol" "HPA028016: , HPA032023: , HPA032031: " "unprognostic (1.23e-1)" "unprognostic (1.40e-1)" "unprognostic (7.00e-2)" "unprognostic (1.90e-2)" "unprognostic (3.71e-2)" "unprognostic (4.49e-2)" "unprognostic (3.38e-1)" "unprognostic (1.40e-3)" "unprognostic (6.77e-2)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (1.50e-4)" "potential prognostic unfavorable (1.68e-7)" "validated prognostic unfavorable (1.88e-4)" "validated prognostic unfavorable (3.93e-5)" "validated prognostic unfavorable (8.52e-7)" "validated prognostic unfavorable (2.51e-4)" "unprognostic (3.71e-2)" "unprognostic (6.00e-2)" "unprognostic (3.42e-1)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (3.66e-4)" "unprognostic (2.53e-2)" "unprognostic (4.27e-2)" "unprognostic (3.50e-1)" "unprognostic (4.25e-3)" "unprognostic (7.39e-2)" "unprognostic (3.63e-1)" "unprognostic (1.42e-2)" "unprognostic (1.51e-1)" DTNBP1 "BLOC1S8, DBND, Dysbindin, HPS7, My031" ENSG00000047579 "Dystrobrevin binding protein 1" Q96EV8 6 15522807-15663058 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction" "Albinism, Hermansky-Pudlak syndrome, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 89.8;retina: 117.7" "Cell type enhanced" "Detected in all" "Retinal amacrine cells: 254.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "blood vessel: 6209222.7" "HPA028053, HPA029615, HPA029616" Approved Enhanced Microtubules,Midbody Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 61 Microtubules Midbody "HPA028053: , HPA029615: , HPA029616: " "unprognostic (1.03e-1)" "unprognostic (1.29e-1)" "unprognostic (1.04e-1)" "unprognostic (8.42e-2)" "unprognostic (8.80e-2)" "unprognostic (8.93e-2)" "unprognostic (4.43e-2)" "unprognostic (1.55e-1)" "unprognostic (3.16e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (6.32e-4)" "unprognostic (7.94e-3)" "unprognostic (2.38e-1)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (3.34e-3)" "unprognostic (7.11e-3)" "unprognostic (2.56e-1)" "unprognostic (8.44e-2)" "unprognostic (6.10e-2)" "unprognostic (2.02e-2)" "unprognostic (2.11e-1)" "unprognostic (1.25e-2)" "unprognostic (1.57e-1)" "unprognostic (3.16e-1)" "unprognostic (5.20e-2)" "unprognostic (2.06e-2)" "unprognostic (7.55e-2)" "unprognostic (1.36e-1)" "unprognostic (7.71e-2)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" DTWD1 "MDS009, MGC111207" ENSG00000104047 "DTW domain containing 1" Q8N5C7 15 49621037-49656232 "Enzymes, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 68 "Fallopian tube cells: 5363.1;Granulosa cells: 8244.2" "Tissue enriched" "Detected in single" 1753 "intestine: 175265.6" HPA042214 Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Vesicles" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: Non-specific - Transcription" "Nucleoli rim" "Nucleoplasm, Mitotic chromosome, Vesicles" "HPA042214: " "unprognostic (7.23e-2)" "unprognostic (4.60e-1)" "unprognostic (2.81e-1)" "unprognostic (3.29e-3)" "unprognostic (1.31e-1)" "unprognostic (1.32e-1)" "unprognostic (1.27e-1)" "unprognostic (8.74e-2)" "unprognostic (8.45e-2)" "unprognostic (2.13e-3)" "potential prognostic favorable (1.96e-5)" "unprognostic (6.08e-3)" "unprognostic (3.58e-1)" "unprognostic (9.64e-2)" "unprognostic (2.43e-1)" "unprognostic (1.03e-1)" "unprognostic (7.32e-2)" "unprognostic (2.77e-1)" "unprognostic (6.86e-2)" "unprognostic (1.02e-1)" "unprognostic (2.06e-2)" "unprognostic (1.51e-3)" "unprognostic (6.25e-2)" "unprognostic (4.89e-1)" "unprognostic (2.35e-2)" "unprognostic (7.62e-2)" "unprognostic (5.69e-3)" "unprognostic (1.76e-1)" "unprognostic (1.49e-1)" "unprognostic (7.89e-3)" "unprognostic (2.91e-3)" DTX3 "FLJ34766, RNF154" ENSG00000178498 "Deltex E3 ubiquitin ligase 3" Q8N9I9 12 57604622-57609804 "Enzymes, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 50.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 206.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "NK-cells: 1.0;T-cells: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 1158129.9;Microglia and Neuropil: 1907126.8;Neurons: 1014035.0;Pancreatic islets: 547426.9" "Tissue enriched" "Detected in some" "cerebral cortex: 1226742.6" HPA059654 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus" No No "Cluster 27: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 110: Mural cells - ECM organization" 40 "Nucleoplasm, Nucleoli" "Golgi apparatus" "HPA059654: " "unprognostic (1.19e-3)" "unprognostic (7.94e-2)" "unprognostic (6.53e-2)" "unprognostic (1.16e-1)" "unprognostic (2.27e-2)" "unprognostic (1.80e-1)" "unprognostic (4.55e-1)" "unprognostic (5.27e-3)" "unprognostic (4.32e-2)" "unprognostic (9.84e-2)" "unprognostic (6.44e-2)" "unprognostic (7.94e-2)" "unprognostic (1.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-1)" "unprognostic (8.52e-2)" "unprognostic (1.87e-1)" "unprognostic (1.02e-3)" "unprognostic (5.04e-3)" "unprognostic (1.45e-1)" "unprognostic (2.10e-1)" "potential prognostic favorable (6.15e-4)" "unprognostic (1.02e-1)" "unprognostic (1.46e-1)" "unprognostic (1.08e-1)" "unprognostic (4.00e-2)" "unprognostic (6.15e-2)" "unprognostic (9.57e-2)" "unprognostic (1.45e-1)" "unprognostic (6.69e-2)" "unprognostic (1.47e-1)" DTYMK "CDC8, TMPK, TYMK" ENSG00000168393 "Deoxythymidylate kinase" P23919 2 241675747-241686944 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 107.9;Erythrocyte progenitors: 127.1;Esophageal basal cells: 161.6;Extravillous trophoblasts: 172.4;Hofbauer cells: 102.2;Migrating cytotrophoblasts: 128.1" "Cell type enhanced" "Detected in many" "Basal cells: 161.6;Trophoblast cells: 172.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA042593, HPA042719" Approved Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 6 Mitochondria "HPA042593: , HPA042719: " "unprognostic (1.69e-1)" "unprognostic (1.01e-1)" "unprognostic (2.84e-1)" "unprognostic (3.66e-1)" "unprognostic (2.81e-1)" "unprognostic (1.55e-2)" "unprognostic (3.44e-1)" "unprognostic (9.10e-3)" "unprognostic (7.78e-2)" "unprognostic (3.53e-2)" "validated prognostic unfavorable (2.35e-4)" "validated prognostic unfavorable (1.97e-4)" "unprognostic (3.35e-1)" "validated prognostic unfavorable (7.02e-7)" "validated prognostic unfavorable (2.23e-12)" "potential prognostic unfavorable (2.15e-5)" "unprognostic (2.22e-3)" "unprognostic (3.31e-2)" "unprognostic (2.08e-1)" "unprognostic (2.65e-1)" "unprognostic (4.54e-2)" "unprognostic (2.04e-3)" "unprognostic (3.78e-2)" "unprognostic (2.37e-1)" "unprognostic (4.68e-1)" "unprognostic (7.45e-3)" "unprognostic (2.36e-3)" "unprognostic (1.00e-1)" "unprognostic (3.31e-1)" "unprognostic (7.38e-2)" "unprognostic (3.21e-2)" DUSP11 PIR1 ENSG00000144048 "Dual specificity phosphatase 11" O75319 2 73761782-73780132 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 217.9;Oocytes: 124.3" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 217.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 700497.5;Fallopian tube cells: 857443.5;Granulosa cells: 2347190.0;T-cells: 1123080.1" "Group enriched" "Detected in some" 22054 "intestine: 2325960.5;lymphoid tissue: 2084811.8" HPA021052 Supported "Nucleoplasm,Nucleoli fibrillar center,Cytokinetic bridge" Yes Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 4 "Nucleoplasm, Nucleoli fibrillar center" "Cytokinetic bridge" "HPA021052: " "unprognostic (2.07e-2)" "unprognostic (2.03e-1)" "unprognostic (9.61e-2)" "unprognostic (2.09e-1)" "unprognostic (3.73e-2)" "unprognostic (4.74e-1)" "unprognostic (1.07e-1)" "unprognostic (4.41e-2)" "unprognostic (9.24e-3)" "unprognostic (5.33e-2)" "potential prognostic favorable (8.79e-6)" "unprognostic (2.08e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (4.43e-8)" "unprognostic (3.10e-3)" "unprognostic (2.75e-2)" "unprognostic (1.95e-3)" "unprognostic (1.51e-2)" "unprognostic (1.07e-1)" "unprognostic (2.59e-1)" "unprognostic (2.29e-2)" "unprognostic (2.31e-2)" "unprognostic (2.04e-3)" "unprognostic (3.48e-2)" "unprognostic (7.25e-2)" "unprognostic (2.45e-1)" "unprognostic (2.08e-2)" "unprognostic (3.15e-1)" "unprognostic (5.01e-1)" "unprognostic (1.79e-1)" "unprognostic (2.02e-1)" DUSP18 DUSP20 ENSG00000167065 "Dual specificity phosphatase 18" Q8NEJ0 22 30652051-30667887 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 225.7;Early spermatids: 143.8;Ependymal cells: 111.9;Fallopian tube ciliated cells: 97.6;Late primary spermatocytes: 119.8;Late spermatids: 643.9;Respiratory ciliated cells: 173.2" "Group enriched" "Detected in many" 4 "Alveolar cells: 225.7;Ciliated cells: 173.2;Spermatogenic cell types: 643.9" "Cell type enhanced" "Detected in all" "ependymal cell: 126.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034070, HPA051349" Uncertain Supported Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 5 Nucleoplasm "CAB034070: , HPA051349: " "unprognostic (4.93e-2)" "unprognostic (1.26e-1)" "unprognostic (1.43e-1)" "unprognostic (1.58e-2)" "unprognostic (2.07e-2)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (4.91e-2)" "unprognostic (7.95e-2)" "unprognostic (2.73e-1)" "unprognostic (2.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.02e-1)" "unprognostic (3.45e-1)" "unprognostic (2.96e-1)" "unprognostic (5.75e-2)" "unprognostic (2.55e-2)" "unprognostic (3.24e-2)" "unprognostic (1.63e-1)" "unprognostic (9.47e-2)" "unprognostic (8.96e-2)" "unprognostic (4.18e-1)" "unprognostic (3.72e-1)" "potential prognostic favorable (8.13e-4)" "unprognostic (2.92e-1)" "unprognostic (1.34e-1)" "unprognostic (4.74e-2)" "unprognostic (3.98e-2)" "unprognostic (2.53e-2)" "unprognostic (4.63e-2)" DUSP19 "DUSP17, SKRP1" ENSG00000162999 "Dual specificity phosphatase 19" Q8WTR2 2 183078559-183100008 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 28.7;Late primary spermatocytes: 32.2;Megakaryocytes: 24.7;Parietal cells: 109.6;Respiratory ciliated cells: 26.9" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 109.6;Spermatogenic cell types: 32.2" "Cell type enhanced" "Detected in all" "hippocampal CA4: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 212205.5;Distal tubules: 218329.8;Fallopian tube cells: 208335.2;Large ducts: 220924.5" "Not detected" "Not detected" HPA021501 Approved Approved Nucleoplasm Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 97: Non-specific - Cellular respiration" 7 Nucleoplasm "HPA021501: " "unprognostic (1.30e-2)" "unprognostic (8.68e-2)" "unprognostic (2.78e-2)" "unprognostic (1.19e-1)" "unprognostic (2.66e-1)" "unprognostic (1.35e-1)" "unprognostic (3.05e-3)" "unprognostic (6.64e-2)" "unprognostic (1.65e-3)" "unprognostic (2.12e-2)" "unprognostic (4.48e-1)" "unprognostic (2.52e-2)" "unprognostic (1.94e-1)" "unprognostic (3.13e-2)" "unprognostic (6.20e-2)" "unprognostic (9.39e-2)" "unprognostic (5.93e-2)" "unprognostic (1.01e-1)" "unprognostic (2.88e-1)" "unprognostic (1.70e-2)" "unprognostic (6.03e-2)" "unprognostic (5.79e-2)" "unprognostic (9.28e-2)" "unprognostic (2.26e-1)" DUSP21 ENSG00000189037 "Dual specificity phosphatase 21" Q9H596 X 44844021-44844888 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 42 "testis: 10.2" "Cell type enriched" "Detected in some" 5 "Late spermatids: 518.9" "Cell type enriched" "Detected in single" 1020 "Spermatogenic cell types: 518.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059171 Approved "Nucleoli,Centrosome,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 17 Centrosome "Nucleoli, Connecting piece, Mid piece, Principal piece" "HPA059171: " DUSP26 "DUSP24, MGC1136, NEAP" ENSG00000133878 "Dual specificity phosphatase 26" Q9BV47 8 33591330-33600023 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 394.8;tongue: 190.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 22.8;Brain inhibitory neurons: 24.9;Cone photoreceptor cells: 35.2;Corticotrophs: 43.8;Lactotrophs: 29.7;Myonuclei: 53.6;Neuroendocrine cells: 23.3;Other brain neurons: 39.7;Pancreatic islet cells: 51.5;Retinal amacrine cells: 24.8;Retinal bipolar cells: 52.8;Rod photoreceptor cells: 48.5;Somatotrophs: 29.0;Thymic myoid cells: 74.8;Thyrotrophs: 24.6" "Cell type enhanced" "Detected in many" "Myocytes: 53.6;Neuronal cells: 52.8;Pancreatic islet cells: 51.5;Pituitary endocrine cells: 43.8;Stromal cells: 74.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 14.2;Pancreatic Adenocarcinoma (TCGA): 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 8.8;Neuroblastoma: 28.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Skeletal myofibers: 55328607.5" "Group enriched" "Detected in some" 11301 "cerebral cortex: 792754.0;skeletal muscle: 1467347.3" HPA018221 Approved Supported Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 10 Nucleoplasm "HPA018221: " "unprognostic (2.31e-3)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.31e-4)" "unprognostic (7.75e-2)" "unprognostic (1.89e-3)" "unprognostic (2.84e-3)" "unprognostic (2.56e-1)" "unprognostic (8.67e-3)" "unprognostic (1.09e-1)" "unprognostic (6.40e-2)" DUSP28 "DUSP26, VHP" ENSG00000188542 "Dual specificity phosphatase 28" Q4G0W2 2 240560054-240565256 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 55.0;Early primary spermatocytes: 35.8;Early spermatids: 39.8;Late primary spermatocytes: 49.0;Late spermatids: 52.9" "Cell type enhanced" "Detected in many" "Myocytes: 55.0;Spermatogenic cell types: 52.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 8.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 8.8" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells, Skeletal muscle - Skeletal myocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Skeletal myofibers: 2906463.0" "Tissue enriched" "Detected in some" "skeletal muscle: 2321397.7" "HPA047456, CAB069448" Uncertain Uncertain "Nuclear speckles,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nuclear speckles" Cytosol "CAB069448: , HPA047456: " "unprognostic (8.87e-3)" "unprognostic (1.26e-1)" "unprognostic (3.70e-2)" "unprognostic (6.66e-3)" "unprognostic (1.39e-2)" "unprognostic (2.31e-1)" "unprognostic (3.05e-1)" "unprognostic (8.73e-2)" "unprognostic (1.16e-1)" "potential prognostic unfavorable (3.82e-5)" "unprognostic (3.34e-3)" "unprognostic (1.35e-2)" "unprognostic (8.30e-3)" "unprognostic (7.98e-2)" "unprognostic (1.62e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (1.08e-4)" "unprognostic (3.38e-2)" "unprognostic (3.19e-1)" "potential prognostic favorable (1.40e-4)" "unprognostic (2.19e-1)" "unprognostic (6.89e-2)" "unprognostic (7.75e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (6.85e-2)" "unprognostic (2.96e-1)" "unprognostic (1.40e-1)" "unprognostic (4.28e-2)" DUSP9 "MKP-4, MKP4" ENSG00000130829 "Dual specificity phosphatase 9" Q99956 X 153642492-153651326 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "kidney: 52.1;placenta: 68.3" "Group enriched" "Detected in some" 30 "Cytotrophoblasts: 1517.6;Migrating cytotrophoblasts: 545.5;Syncytiotrophoblasts: 1984.4" "Cell type enriched" "Detected in some" 47 "Trophoblast cells: 1984.4" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 11.1" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 15.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Gastric cancer: 21.2;liver cancer: 62.7" "Kidney - Ascending Loop of Henle cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Distal tubules: 17341372.7" "Not detected" "Not detected" HPA003336 Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 "Endoplasmic reticulum" "HPA003336: " "unprognostic (7.31e-2)" "unprognostic (7.66e-2)" "unprognostic (2.43e-2)" "unprognostic (7.00e-2)" "unprognostic (9.46e-2)" "unprognostic (3.57e-3)" "unprognostic (5.97e-2)" "unprognostic (1.29e-2)" "unprognostic (1.50e-2)" "unprognostic (1.13e-2)" "unprognostic (2.75e-3)" "unprognostic (2.27e-2)" "unprognostic (5.27e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (2.60e-1)" "unprognostic (8.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.41e-2)" "unprognostic (1.94e-1)" "unprognostic (3.86e-3)" DUT dUTPase ENSG00000128951 "Deoxyuridine triphosphatase" P33316 15 48331011-48343373 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 616.9;Erythrocyte progenitors: 735.6;Megakaryocyte progenitors: 588.7" "Cell type enhanced" "Detected in all" "Erythrocytes: 735.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA054422, HPA060360" Enhanced Supported Nucleoplasm No Yes 15000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 4 Nucleoplasm "HPA054422: , HPA060360: " "unprognostic (3.72e-2)" "unprognostic (1.27e-2)" "unprognostic (1.81e-1)" "unprognostic (3.80e-2)" "unprognostic (5.26e-3)" "unprognostic (8.32e-2)" "unprognostic (1.16e-2)" "unprognostic (7.62e-2)" "unprognostic (1.77e-1)" "unprognostic (3.35e-3)" "potential prognostic favorable (3.82e-4)" "unprognostic (4.76e-2)" "unprognostic (5.97e-2)" "unprognostic (1.62e-1)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (7.15e-4)" "unprognostic (5.88e-2)" "unprognostic (9.07e-3)" "unprognostic (6.44e-2)" "unprognostic (7.68e-2)" "unprognostic (1.91e-1)" "unprognostic (3.00e-2)" "unprognostic (5.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.02e-2)" "unprognostic (2.96e-2)" "unprognostic (6.89e-3)" "unprognostic (6.30e-2)" "unprognostic (1.38e-1)" "unprognostic (1.97e-3)" "unprognostic (3.24e-2)" DVL3 KIAA0208 ENSG00000161202 "Dishevelled segment polarity protein 3" Q92997 3 184155377-184173614 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 288678.9;Fallopian tube cells: 287449.3;Proximal tubules: 305845.8" "Low tissue specificity" "Detected in many" "CAB046486, HPA058265" Approved Approved "Golgi apparatus,Plasma membrane,Intermediate filaments,Midbody ring,Centrosome,Basal body" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 74: Non-specific - Signal transduction" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 152 "Midbody ring, Basal body" "Golgi apparatus, Plasma membrane, Intermediate filaments, Centrosome" "CAB046486: , HPA058265: " "unprognostic (2.01e-1)" "unprognostic (2.20e-2)" "unprognostic (4.18e-1)" "unprognostic (6.29e-2)" "unprognostic (6.64e-3)" "unprognostic (1.41e-1)" "unprognostic (2.68e-2)" "unprognostic (5.97e-2)" "unprognostic (3.54e-1)" "unprognostic (2.91e-2)" "unprognostic (2.79e-3)" "unprognostic (8.30e-3)" "unprognostic (2.57e-2)" "unprognostic (1.14e-3)" "unprognostic (3.16e-2)" "unprognostic (2.33e-2)" "unprognostic (1.73e-2)" "unprognostic (3.80e-2)" "potential prognostic favorable (1.41e-4)" "unprognostic (4.48e-1)" "unprognostic (3.25e-2)" "unprognostic (7.03e-2)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (7.04e-5)" "unprognostic (2.00e-2)" "unprognostic (1.23e-1)" "unprognostic (7.46e-2)" "unprognostic (1.83e-1)" "unprognostic (4.87e-1)" "unprognostic (7.61e-2)" "unprognostic (1.93e-1)" DYDC2 "bA36D19.6, MGC16186" ENSG00000133665 "DPY30 domain containing 2" Q96IM9 10 80344745-80368073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 25.3;fallopian tube: 91.5" "Cell type enhanced" "Detected in some" "Early spermatids: 51.4;Endometrial ciliated cells: 218.3;Ependymal cells: 82.8;Epididymal efferent duct ciliated cells: 183.8;Fallopian tube ciliated cells: 296.1;Late primary spermatocytes: 81.9;Late spermatids: 49.6;Respiratory ciliated cells: 261.3" "Group enriched" "Detected in some" 15 "Ciliated cells: 296.1;Spermatogenic cell types: 81.9" "Cell type enriched" "Detected in many" 10 "ependymal cell: 132.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 13.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 54880 "Fallopian tube cells: 5488000.2" "Tissue enriched" "Detected in single" 51191 "fallopian tube: 5119058.3" "HPA038006, HPA038007" Enhanced Approved "Vesicles,Cytosol,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 9 "Vesicles, Principal piece" Cytosol "HPA038006: , HPA038007: " "unprognostic (7.08e-2)" "unprognostic (2.25e-1)" "unprognostic (1.05e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (2.66e-1)" "unprognostic (2.57e-1)" "unprognostic (3.45e-1)" "unprognostic (2.60e-2)" "unprognostic (3.34e-1)" "unprognostic (1.61e-1)" "unprognostic (1.41e-1)" "unprognostic (1.52e-2)" "unprognostic (6.80e-2)" "unprognostic (3.20e-3)" "unprognostic (1.15e-2)" "unprognostic (3.02e-2)" "unprognostic (9.28e-2)" DYNC1LI2 DNCLI2 ENSG00000135720 "Dynein cytoplasmic 1 light intermediate chain 2" O43237 16 66720893-66751609 "Predicted intracellular proteins" Transport "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 269.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 39184391.3" "HPA049538, HPA057201" Approved Approved "Centrosome,Cytosol,End piece" NA NA 19000 "Cluster 28: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 17: Non-specific - RNA processing" 34 "Centrosome, End piece" Cytosol "HPA049538: , HPA057201: " "unprognostic (6.60e-2)" "unprognostic (5.63e-2)" "unprognostic (3.48e-1)" "unprognostic (7.75e-2)" "unprognostic (5.13e-1)" "unprognostic (2.75e-2)" "unprognostic (4.37e-2)" "unprognostic (7.76e-2)" "unprognostic (1.12e-1)" "unprognostic (1.46e-2)" "validated prognostic favorable (5.39e-5)" "validated prognostic favorable (7.96e-4)" "unprognostic (2.29e-1)" "unprognostic (6.02e-3)" "unprognostic (6.49e-2)" "unprognostic (4.13e-2)" "unprognostic (7.18e-2)" "unprognostic (4.71e-3)" "unprognostic (8.11e-2)" "unprognostic (1.23e-1)" "unprognostic (2.06e-3)" "unprognostic (2.20e-2)" "unprognostic (4.14e-3)" "unprognostic (2.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.78e-1)" "unprognostic (2.09e-1)" "unprognostic (1.60e-2)" "unprognostic (1.93e-1)" "unprognostic (1.59e-2)" "unprognostic (5.70e-2)" DYNC2H1 "DHC1b, DHC2, DNCH2, DYH1B, hdhc11" ENSG00000187240 "Dynein cytoplasmic 2 heavy chain 1" Q8NCM8 11 103109410-103479863 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 18.0" "Cell type enhanced" "Detected in all" "Corticotrophs: 481.2;Distal convoluted tubule cells: 495.3;Endometrial ciliated cells: 568.1;Ependymal cells: 1088.9;Fallopian tube ciliated cells: 539.2;Respiratory ciliated cells: 952.2;Somatotrophs: 435.2;Thyrotrophs: 431.0" "Cell type enhanced" "Detected in all" "Ciliated cells: 1088.9;Pituitary endocrine cells: 481.2;Renal nephron cells: 495.3" "Cell type enhanced" "Detected in all" "ependymal cell: 1183.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 85846435.5" "Group enriched" "Detected in many" "fallopian tube: 206779.4;intestine: 60266.8;salivary gland: 201131.5" "HPA039015, HPA039016" Approved Approved "Nucleoplasm,Mitochondria,Cytosol,Mid piece,Principal piece" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 3: Rhabdoid - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 7 "Mitochondria, Mid piece" "Nucleoplasm, Cytosol, Principal piece" "HPA039015: , HPA039016: " "unprognostic (1.13e-2)" "unprognostic (3.02e-1)" "unprognostic (9.08e-2)" "unprognostic (1.37e-2)" "unprognostic (3.76e-2)" "unprognostic (3.43e-1)" "unprognostic (2.75e-1)" "unprognostic (9.25e-3)" "unprognostic (1.29e-2)" "validated prognostic favorable (5.10e-11)" "validated prognostic favorable (1.27e-4)" "unprognostic (5.29e-2)" "unprognostic (2.78e-2)" "unprognostic (3.12e-2)" "unprognostic (1.13e-1)" "unprognostic (2.43e-1)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (8.18e-2)" "unprognostic (2.93e-1)" "unprognostic (1.64e-3)" "unprognostic (9.46e-2)" "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (1.37e-1)" DYNC2I1 "CFAP163, DIC6, FAP163, FLJ10300, WDR60" ENSG00000126870 "Dynein 2 intermediate chain 1" Q8WVS4 7 158856558-158956747 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 575.7;Endometrial ciliated cells: 489.5;Ependymal cells: 695.7;Late primary spermatocytes: 888.4;Respiratory ciliated cells: 501.8" "Cell type enhanced" "Detected in all" "Ciliated cells: 695.7;Spermatogenic cell types: 888.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 7466323.4" "Group enriched" "Detected in many" "fallopian tube: 4325544.4;ovary: 2076325.4" "HPA020607, HPA021316" Approved Supported "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 39: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 28 "Centrosome, Basal body" "Primary cilium, Cytosol" "HPA020607: , HPA021316: " "unprognostic (3.79e-2)" "unprognostic (4.51e-1)" "unprognostic (1.31e-1)" "unprognostic (3.33e-1)" "unprognostic (3.77e-1)" "unprognostic (2.55e-1)" "unprognostic (2.30e-1)" "unprognostic (5.86e-2)" "unprognostic (6.07e-3)" "potential prognostic favorable (5.24e-4)" "unprognostic (1.16e-1)" "unprognostic (4.76e-3)" "unprognostic (1.88e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-3)" "unprognostic (5.09e-1)" "unprognostic (1.46e-1)" "unprognostic (7.05e-2)" "unprognostic (2.90e-1)" "unprognostic (1.50e-1)" "unprognostic (2.69e-3)" "unprognostic (3.29e-1)" "unprognostic (1.48e-1)" "unprognostic (3.14e-1)" "unprognostic (9.70e-2)" "unprognostic (1.95e-1)" "unprognostic (6.64e-2)" "unprognostic (2.22e-3)" "unprognostic (6.78e-2)" DYNC2I2 "bA216B9.3, CFAP133, DIC5, FAP133, MGC20486, WDR34" ENSG00000119333 "Dynein 2 intermediate chain 2" Q96EX3 9 128633653-128656847 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 165.9;Enterocytes: 154.5;Fallopian tube ciliated cells: 155.7;Late primary spermatocytes: 156.4;Late spermatids: 367.9;Oocytes: 165.8;Respiratory ciliated cells: 195.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 367.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 37.9;ependymal cell: 40.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 35.9;naive B-cell: 53.2" "Lineage enriched" "Detected in all" 5 "B-cells: 53.2" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 4965252.8" "Tissue enriched" "Detected in some" "fallopian tube: 2716840.0" "HPA040764, HPA041091" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Primary cilium,Centrosome,Basal body,Cytosol" NA Yes "Cluster 17: B-cells - Immunoglobulins" "Cluster 70: Non-specific - Protein processing" "Cluster 3: Choroid plexus - Cilium" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 35 "Nucleoplasm, Centrosome, Basal body" "Nucleoli, Nuclear bodies, Primary cilium, Cytosol" "HPA040764: , HPA041091: " "unprognostic (1.59e-1)" "unprognostic (4.79e-3)" "unprognostic (6.90e-3)" "unprognostic (2.40e-1)" "unprognostic (9.47e-2)" "unprognostic (2.66e-1)" "unprognostic (2.09e-1)" "unprognostic (2.12e-3)" "unprognostic (1.07e-1)" "potential prognostic favorable (8.09e-5)" "unprognostic (4.07e-2)" "potential prognostic favorable (8.31e-5)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (2.60e-3)" "unprognostic (4.11e-2)" "unprognostic (4.29e-2)" "unprognostic (4.87e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (5.23e-4)" "unprognostic (1.70e-1)" "unprognostic (1.49e-1)" "unprognostic (8.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.46e-2)" "unprognostic (3.47e-1)" "unprognostic (4.57e-2)" "unprognostic (4.31e-1)" "unprognostic (3.89e-2)" "unprognostic (2.30e-3)" DYNC2LI1 "CGI-60, D2LIC, DKFZP564A033, LIC3" ENSG00000138036 "Dynein cytoplasmic 2 light intermediate chain 1" Q8TCX1 2 43774039-43810010 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein, Motor protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 202.5;Late primary spermatocytes: 330.9;Respiratory ciliated cells: 225.1" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 330.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 92.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 15.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 4060666.3" "Tissue enriched" "Detected in single" 1621 "fallopian tube: 162130.5" HPA062905 Approved Supported "Primary cilium,Basal body,Cytosol,Equatorial segment,Perinuclear theca,Mid piece,Principal piece,Annulus" NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 15 "Cytosol, Mid piece" "Primary cilium, Basal body, Equatorial segment, Perinuclear theca, Principal piece, Annulus" "HPA062905: " "unprognostic (3.85e-1)" "unprognostic (1.31e-1)" "unprognostic (3.84e-1)" "unprognostic (6.16e-2)" "unprognostic (1.84e-1)" "unprognostic (1.54e-2)" "unprognostic (3.32e-2)" "unprognostic (2.47e-2)" "unprognostic (3.57e-2)" "unprognostic (1.70e-1)" "potential prognostic favorable (1.52e-7)" "unprognostic (1.33e-2)" "potential prognostic favorable (4.48e-4)" "potential prognostic unfavorable (2.86e-4)" "unprognostic (4.31e-3)" "unprognostic (7.98e-2)" "unprognostic (5.66e-2)" "unprognostic (3.60e-1)" "unprognostic (4.39e-1)" "unprognostic (4.60e-1)" "unprognostic (1.59e-2)" "unprognostic (2.14e-2)" "unprognostic (3.08e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (2.45e-4)" "unprognostic (3.65e-1)" "unprognostic (5.31e-2)" "unprognostic (1.94e-1)" "unprognostic (2.54e-1)" "unprognostic (5.18e-2)" "unprognostic (9.00e-2)" DYNLT2B "MGC33212, TCTEX1D2" ENSG00000213123 "Dynein light chain Tctex-type 2B" Q8WW35 3 196291219-196318299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Differentiating spermatogonia: 115.9;Early primary spermatocytes: 347.0;Early spermatids: 198.9;Endometrial ciliated cells: 202.4;Epididymal efferent duct ciliated cells: 360.9;Fallopian tube ciliated cells: 423.9;Late primary spermatocytes: 242.4;Respiratory ciliated cells: 338.8" "Group enriched" "Detected in many" 5 "Ciliated cells: 423.9;Spermatogenic cell types: 347.0" "Cell type enhanced" "Detected in all" "ependymal cell: 29.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 5 "B-cells: 22.0;dendritic cells: 16.2;T-cells: 25.2" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1541 "Fallopian tube cells: 154149.1" "Tissue enriched" "Detected in some" "fallopian tube: 8530411.0" HPA049555 Approved "Microtubules,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 18: Non-specific - Translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 17: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 28 "Microtubules, Primary cilium" "Mitotic spindle, Basal body, Cytosol" "HPA049555: " "unprognostic (2.58e-3)" "unprognostic (7.55e-3)" "potential prognostic favorable (2.67e-4)" "unprognostic (3.56e-2)" "unprognostic (2.86e-1)" "unprognostic (1.82e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (6.85e-2)" "unprognostic (2.79e-1)" "unprognostic (7.68e-2)" "unprognostic (3.88e-2)" "unprognostic (2.14e-2)" "unprognostic (3.00e-3)" "unprognostic (1.14e-2)" "unprognostic (1.20e-1)" "unprognostic (4.70e-2)" "unprognostic (2.56e-2)" "unprognostic (1.30e-1)" "unprognostic (5.00e-2)" "unprognostic (1.12e-1)" "unprognostic (1.03e-1)" "unprognostic (3.09e-1)" "unprognostic (6.02e-2)" "unprognostic (4.09e-1)" "unprognostic (1.92e-1)" "unprognostic (4.71e-1)" "unprognostic (6.08e-2)" DYRK1B MIRK ENSG00000105204 "Dual specificity tyrosine phosphorylation regulated kinase 1B" Q9Y463 19 39825350-39834201 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 124.8;testis: 79.9" "Cell type enhanced" "Detected in some" "Astrocytes: 8.4;Bergmann glia: 6.8;Brain excitatory neurons: 8.3;Brain inhibitory neurons: 10.1;Choroid plexus epithelial cells: 17.1;Distal convoluted tubule cells: 8.9;Ependymal cells: 18.3;Late spermatids: 13.8;Loop of henle epithelial cells: 8.9;Oligodendrocyte progenitor cells: 8.4;Oligodendrocytes: 8.4;Other brain neurons: 10.2;Papillary tip epithelial cells: 6.4;Podocytes: 10.8;Proximal tubule cells: 15.2;Renal collecting duct principal cells: 7.1;Renal connecting tubule cells: 6.8" "Cell type enhanced" "Detected in some" "Ciliated cells: 18.3;Ductal cells: 7.1;Glial cells: 8.4;Neuronal cells: 10.2;Renal nephron cells: 15.2;Spermatogenic cell types: 13.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Skeletal myofibers: 999483.4" "Tissue enriched" "Detected in some" "cerebral cortex: 114144.8" "HPA028522, HPA028786" Uncertain Supported "Nucleoplasm,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 51 Nucleoplasm "Mitotic chromosome" "HPA028522: , HPA028786: " "unprognostic (4.38e-3)" "unprognostic (1.51e-1)" "unprognostic (4.14e-1)" "unprognostic (7.03e-2)" "unprognostic (1.60e-1)" "unprognostic (2.77e-1)" "unprognostic (1.17e-1)" "unprognostic (2.61e-2)" "unprognostic (5.93e-3)" "unprognostic (2.64e-1)" "unprognostic (1.27e-2)" "unprognostic (5.31e-2)" "potential prognostic favorable (8.31e-5)" "unprognostic (1.21e-1)" "unprognostic (4.05e-1)" "unprognostic (1.01e-1)" "unprognostic (8.15e-2)" "unprognostic (1.46e-2)" "unprognostic (7.85e-2)" "unprognostic (1.25e-3)" "unprognostic (1.35e-1)" "unprognostic (1.33e-1)" "unprognostic (4.26e-2)" "unprognostic (3.75e-2)" "unprognostic (2.00e-1)" "unprognostic (6.45e-2)" "unprognostic (3.55e-1)" "unprognostic (1.03e-1)" "unprognostic (5.39e-2)" "unprognostic (2.03e-1)" "unprognostic (4.34e-2)" DYRK4 ENSG00000010219 "Dual specificity tyrosine phosphorylation regulated kinase 4" Q9NR20 12 4562208-4615302 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.3" "Group enriched" "Detected in many" 7 "Early spermatids: 338.6;Late spermatids: 446.7" "Cell type enriched" "Detected in many" 19 "Spermatogenic cell types: 446.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028065, HPA056073" Enhanced Enhanced Vesicles No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 38: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 9 Vesicles "HPA028065: , HPA056073: " "unprognostic (5.15e-3)" "unprognostic (7.32e-2)" "unprognostic (4.40e-2)" "unprognostic (1.39e-2)" "unprognostic (1.40e-1)" "unprognostic (3.23e-1)" "unprognostic (6.17e-2)" "unprognostic (8.49e-2)" "unprognostic (7.29e-3)" "unprognostic (1.62e-2)" "unprognostic (3.48e-2)" "unprognostic (2.27e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (3.20e-1)" "unprognostic (9.16e-2)" "unprognostic (1.64e-1)" "unprognostic (7.92e-2)" "unprognostic (2.53e-2)" "unprognostic (1.21e-2)" "unprognostic (2.35e-1)" "unprognostic (5.85e-2)" "unprognostic (3.31e-2)" "unprognostic (4.46e-1)" "unprognostic (9.78e-3)" "unprognostic (6.11e-3)" "unprognostic (6.56e-2)" "unprognostic (3.07e-2)" "unprognostic (4.28e-2)" "unprognostic (3.77e-3)" "unprognostic (4.82e-2)" DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453561-71686763 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.3;skeletal muscle: 119.0" "Cell type enriched" "Detected in many" 4 "Neutrophils: 2844.8" "Cell type enriched" "Detected in many" 5 "Neutrophils: 2844.8" "Cell type enhanced" "Detected in all" "mammillary body: 168.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 22.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "neutrophil: 51.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 51.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Neutrophils_2, Minor Salivary Gland - Endothelial cells, Spleen - Neutrophils_2, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 189970101.6;Skeletal myofibers: 212048056.2" "Tissue enhanced" "Detected in all" "skeletal muscle: 94346169.5" "CAB002510, HPA017071, HPA021945" Enhanced Approved "Plasma membrane,Centriolar satellite,Mid piece" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 72: Neuronal - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 47 "Plasma membrane, Centriolar satellite, Mid piece" "CAB002510: , HPA017071: , HPA021945: " "unprognostic (9.90e-2)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.21e-2)" "unprognostic (3.84e-2)" "unprognostic (2.45e-1)" "unprognostic (3.29e-1)" "unprognostic (1.01e-1)" "unprognostic (3.32e-1)" "unprognostic (4.09e-1)" "validated prognostic favorable (2.13e-11)" "validated prognostic favorable (7.59e-4)" "unprognostic (3.10e-1)" "unprognostic (2.80e-1)" "unprognostic (5.39e-3)" "unprognostic (7.17e-2)" "unprognostic (1.45e-2)" "unprognostic (7.23e-2)" "unprognostic (5.53e-2)" "unprognostic (4.52e-2)" "unprognostic (2.84e-1)" "unprognostic (2.53e-2)" "unprognostic (8.42e-2)" "unprognostic (7.85e-2)" "unprognostic (3.80e-2)" "unprognostic (6.45e-2)" "unprognostic (1.90e-2)" "unprognostic (4.23e-2)" "unprognostic (5.27e-2)" "unprognostic (6.90e-2)" DZIP1L "DZIP2, FLJ32844" ENSG00000158163 "DAZ interacting zinc finger protein 1 like" Q8IYY4 3 138061990-138115818 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 56.6;Endometrial ciliated cells: 123.7;Ependymal cells: 107.1;Fallopian tube ciliated cells: 125.7;Respiratory ciliated cells: 209.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 209.8" "Cell type enhanced" "Detected in many" "ependymal cell: 113.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 54572 "Fallopian tube cells: 5457184.6" "Tissue enriched" "Detected in single" 6807 "fallopian tube: 680746.4" HPA030404 Approved Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes No "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 13 "Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "Nucleoplasm, Cytosol" "HPA030404: " "unprognostic (6.53e-2)" "unprognostic (9.54e-2)" "unprognostic (3.89e-1)" "unprognostic (7.38e-3)" "unprognostic (1.69e-1)" "unprognostic (3.81e-3)" "unprognostic (1.07e-1)" "unprognostic (4.64e-2)" "unprognostic (4.02e-1)" "unprognostic (4.66e-2)" "unprognostic (3.03e-2)" "unprognostic (2.62e-1)" "unprognostic (1.09e-1)" "unprognostic (2.97e-1)" "unprognostic (6.70e-2)" "unprognostic (2.11e-1)" "unprognostic (5.34e-2)" "unprognostic (3.85e-3)" "unprognostic (3.70e-1)" "unprognostic (5.66e-2)" "unprognostic (5.68e-2)" "unprognostic (7.11e-2)" "unprognostic (1.02e-1)" "unprognostic (1.23e-2)" "unprognostic (4.51e-1)" "unprognostic (7.22e-2)" "unprognostic (4.27e-3)" DZIP3 "hRUL138, PPP1R66" ENSG00000198919 "DAZ interacting zinc finger protein 3" Q86Y13 3 108589705-108694840 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 538.2;Corticotrophs: 345.7;Early primary spermatocytes: 416.4;Ependymal cells: 388.4;Gonadotrophs: 398.6;Lactotrophs: 269.6;Respiratory ciliated cells: 412.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 412.7;Neuronal cells: 538.2;Pituitary endocrine cells: 398.6;Spermatogenic cell types: 416.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Pituitary gland - Lactotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1126958.5" "Group enriched" "Detected in some" 866 "cerebral cortex: 86855.8;fallopian tube: 86343.0" "HPA035066, HPA049232" Approved Approved Vesicles No No "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 34: Ciliated cells - Cilia assembly & function" 49 Vesicles "HPA035066: , HPA049232: " "unprognostic (2.66e-2)" "unprognostic (1.87e-1)" "unprognostic (3.05e-1)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (4.44e-2)" "unprognostic (4.69e-1)" "unprognostic (1.23e-2)" "unprognostic (1.22e-1)" "unprognostic (3.35e-2)" "potential prognostic favorable (2.48e-7)" "unprognostic (1.03e-2)" "unprognostic (4.39e-2)" "unprognostic (2.33e-1)" "unprognostic (1.22e-1)" "unprognostic (6.58e-3)" "unprognostic (9.41e-2)" "unprognostic (4.25e-1)" "unprognostic (9.84e-2)" "unprognostic (1.89e-1)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (5.12e-2)" "unprognostic (2.90e-1)" "unprognostic (3.20e-3)" "unprognostic (7.38e-3)" "unprognostic (3.05e-1)" "unprognostic (1.11e-1)" "unprognostic (5.69e-2)" "unprognostic (1.06e-2)" "unprognostic (5.38e-2)" E2F7 ENSG00000165891 "E2F transcription factor 7" Q96AV8 12 77021248-77065569 "Predicted intracellular proteins, Transcription factors" "Cell cycle, DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.7;lymphoid tissue: 7.7" "Cell type enhanced" "Detected in many" "Early spermatids: 54.3;Endometrial ciliated cells: 47.6;Ependymal cells: 43.8;Late spermatids: 112.0;Monocyte progenitors: 26.0;Respiratory deuterosomal cells: 64.3;Urothelial cells: 58.3" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 58.3;Ciliated cells: 64.3;Spermatogenic cell types: 112.0" "Cell type enriched" "Detected in some" 19 "ependymal cell: 48.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Corticotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "midbrain: 8.9;pons: 9.6;thalamus: 16.9" "Cell type enriched" "Detected in single" 707 "Granulosa cells: 70713.1" "Not detected" "Not detected" HPA063960 Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 27: Non-specific - Cell proliferation" 6 Nucleoplasm "Primary cilium, Primary cilium tip, Cytosol" "HPA063960: " "unprognostic (6.09e-2)" "unprognostic (2.60e-1)" "unprognostic (2.36e-1)" "unprognostic (1.90e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-2)" "unprognostic (3.27e-1)" "unprognostic (1.40e-1)" "unprognostic (3.73e-1)" "potential prognostic unfavorable (5.02e-4)" "validated prognostic unfavorable (1.13e-4)" "validated prognostic unfavorable (4.46e-4)" "unprognostic (2.12e-1)" "unprognostic (3.18e-2)" "unprognostic (4.22e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.67e-1)" "unprognostic (6.90e-2)" "unprognostic (2.71e-1)" "unprognostic (4.10e-2)" "unprognostic (1.01e-1)" "unprognostic (9.44e-2)" E2F8 FLJ23311 ENSG00000129173 "E2F transcription factor 8" A0AVK6 11 19224063-19241620 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;lymphoid tissue: 11.0;skeletal muscle: 11.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 52.6;Enteric transient amplifying cells: 17.7;Erythrocyte progenitors: 65.0;Gastric chief cells: 16.4;Megakaryocyte progenitors: 24.6;Monocyte progenitors: 66.8;Mucous neck cells: 27.0;Myonuclei: 47.7;Neutrophil progenitors: 31.0;Respiratory deuterosomal cells: 22.8" "Cell type enhanced" "Detected in many" "Erythrocytes: 65.0;Mononuclear phagocytes: 66.8;Myocytes: 52.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skeletal muscle - Skeletal myocytes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 162 "Cardiomyocytes: 16178.3" "Not detected" "Not detected" "HPA064882, HPA076614" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 9: T-regs - Cell cycle regulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 17 "Nucleoplasm, Nucleoli" Cytosol "HPA064882: , HPA076614: " "unprognostic (8.07e-2)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (4.88e-2)" "unprognostic (7.83e-2)" "unprognostic (2.22e-2)" "unprognostic (1.74e-1)" "unprognostic (1.24e-1)" "unprognostic (7.67e-3)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (6.44e-4)" "validated prognostic unfavorable (9.89e-6)" "validated prognostic unfavorable (6.61e-5)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (7.58e-5)" "unprognostic (2.23e-1)" "unprognostic (1.26e-1)" "unprognostic (2.44e-1)" "unprognostic (8.46e-2)" "unprognostic (3.12e-3)" "unprognostic (1.21e-2)" "unprognostic (1.96e-3)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (5.60e-4)" "unprognostic (4.87e-3)" "unprognostic (4.61e-1)" "unprognostic (1.72e-1)" EARS2 "KIAA1970, MSE1, mtGlnRS" ENSG00000103356 "Glutamyl-tRNA synthetase 2, mitochondrial" Q5JPH6 16 23520754-23557731 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA043289, HPA043633" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 21 Mitochondria Nucleoplasm "HPA043289: , HPA043633: " "unprognostic (8.55e-2)" "unprognostic (4.55e-3)" "unprognostic (5.55e-2)" "unprognostic (9.82e-2)" "unprognostic (1.10e-1)" "unprognostic (4.71e-2)" "unprognostic (3.24e-1)" "unprognostic (2.80e-1)" "unprognostic (3.63e-2)" "unprognostic (3.09e-1)" "unprognostic (7.35e-2)" "unprognostic (2.68e-1)" "unprognostic (2.32e-1)" "unprognostic (4.78e-2)" "unprognostic (4.51e-2)" "unprognostic (2.45e-1)" "unprognostic (4.45e-1)" "unprognostic (1.87e-1)" "unprognostic (4.86e-2)" "unprognostic (2.21e-1)" "unprognostic (4.55e-2)" "unprognostic (2.09e-1)" "unprognostic (3.80e-2)" "unprognostic (2.86e-3)" "unprognostic (7.74e-3)" "unprognostic (1.81e-1)" "unprognostic (7.36e-2)" "unprognostic (3.58e-1)" "unprognostic (1.88e-1)" "unprognostic (8.31e-3)" "unprognostic (2.11e-2)" EBF2 "COE2, FLJ11500" ENSG00000221818 "EBF transcription factor 2" Q9HAK2 8 25841725-26045413 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 16.7" "Cell type enhanced" "Detected in many" "Adipocytes: 82.5;Fibro-adipogenic progenitors: 965.5;Fibroblasts: 175.5;Pericytes: 344.3;Renal collecting duct intercalated cells: 99.1;Vascular smooth muscle cells: 152.8" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 965.5;Fibroblasts: 175.5;Mural cells: 344.3" "Cell type enhanced" "Detected in many" "fibroblast: 141.7;splatter: 54.9" "Group enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 14.9;Kidney Renal Clear Cell Carcinoma (TCGA): 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "Sarcoma: 21.9" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells" "Group enriched" "Detected in many" 4 "basal ganglia: 5.7;cerebellum: 3.1;hypothalamus: 2.0;midbrain: 4.4;pons and medulla: 2.8" "Region enriched" "Detected in many" 5 "spinal cord: 11.4" "Cell type enriched" "Detected in single" 2549 "Capillaries: 254940.1" "Not detected" "Not detected" "HPA003954, HPA055101" Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 54: Non-specific - Transcription" "Cluster 110: Mural cells - ECM organization" 3 Nucleoplasm "Nuclear bodies" "HPA003954: , HPA055101: " "unprognostic (1.10e-1)" "unprognostic (3.99e-1)" "unprognostic (6.93e-2)" "unprognostic (6.76e-2)" "unprognostic (3.31e-1)" "unprognostic (1.89e-1)" "unprognostic (3.44e-3)" "potential prognostic favorable (3.21e-5)" "unprognostic (1.58e-1)" "unprognostic (6.35e-2)" "unprognostic (1.97e-1)" "unprognostic (3.79e-2)" "unprognostic (1.64e-1)" "unprognostic (1.76e-2)" EBNA1BP2 "EBP2, NOBP, P40" ENSG00000117395 "EBNA1 binding protein 2" Q99848 1 43164175-43270936 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 396.9;Proximal tubule cells: 388.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 396.9;Renal nephron cells: 388.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 5 "Adrenocortical cancer: 1042.1" "Pituitary gland - Somatotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 7498566.5" "Group enriched" "Detected in many" "fallopian tube: 2281323.8;intestine: 2400665.7;lymphoid tissue: 3488914.0;ovary: 3800062.5" "HPA026512, HPA028277" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 9300 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 88: Proximal tubular cells - Transmembrane transport" 74 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA026512: , HPA028277: " "unprognostic (5.44e-3)" "unprognostic (6.34e-2)" "unprognostic (2.78e-2)" "unprognostic (1.62e-1)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (7.20e-2)" "unprognostic (4.13e-2)" "unprognostic (3.21e-2)" "unprognostic (1.19e-3)" "potential prognostic favorable (2.91e-4)" "unprognostic (3.11e-1)" "unprognostic (3.46e-2)" "potential prognostic unfavorable (1.42e-8)" "unprognostic (5.30e-2)" "unprognostic (3.84e-2)" "unprognostic (1.73e-3)" "unprognostic (8.48e-2)" "unprognostic (2.30e-1)" "unprognostic (2.56e-2)" "unprognostic (9.43e-3)" "unprognostic (3.42e-2)" "unprognostic (5.18e-2)" "unprognostic (1.64e-3)" "unprognostic (1.28e-1)" "unprognostic (4.40e-2)" "unprognostic (2.49e-1)" "unprognostic (3.56e-2)" "unprognostic (3.00e-1)" "unprognostic (1.87e-1)" "unprognostic (1.89e-1)" ECD "GCR2, hSGT1" ENSG00000122882 "Ecdysoneless cell cycle regulator" O95905 10 73130155-73169055 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 489645.6;Hepatocytes: 396581.2;Oocytes: 421502.6;T-cells: 265722.8" "Group enriched" "Detected in some" 244 "bone marrow: 35482.5;lymphoid tissue: 13387.6" HPA006465 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 28: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 55 "Nucleoplasm, Cytosol" "HPA006465: " "unprognostic (1.72e-2)" "unprognostic (3.65e-2)" "unprognostic (3.83e-1)" "unprognostic (4.48e-2)" "unprognostic (1.60e-1)" "unprognostic (8.52e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (1.07e-6)" "unprognostic (6.99e-2)" "potential prognostic unfavorable (4.79e-5)" "unprognostic (1.38e-3)" "unprognostic (2.06e-2)" "unprognostic (1.94e-1)" "unprognostic (2.22e-3)" "unprognostic (1.60e-1)" "unprognostic (7.64e-2)" "unprognostic (1.80e-2)" "unprognostic (9.68e-2)" "unprognostic (8.39e-2)" "unprognostic (4.41e-2)" "unprognostic (1.06e-1)" "unprognostic (1.59e-2)" "unprognostic (4.50e-3)" "unprognostic (3.33e-1)" "unprognostic (5.26e-3)" "unprognostic (6.89e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (2.77e-1)" "unprognostic (1.50e-1)" "unprognostic (3.79e-1)" ECEL1 "DINE, XCE" ENSG00000171551 "Endothelin converting enzyme like 1" O95672 2 232479827-232487834 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 84.5;ovary: 97.5;pituitary gland: 28.1" "Cell type enhanced" "Detected in some" "Corticotrophs: 10.7;Lactotrophs: 9.0;Müller glia: 109.4;Other brain neurons: 62.6;Ovarian stromal cells: 9.0;Peritubular myoid cells: 21.0;Retinal bipolar cells: 22.7;Somatotrophs: 16.9;Thyrotrophs: 8.7" "Group enriched" "Detected in some" 4 "Glial cells: 109.4;Neuronal cells: 62.6" "Cell type enriched" "Detected in many" 5 "splatter: 16.1" "Cancer enriched" "Detected in many" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 31.4" "Region enhanced" "Detected in all" "hypothalamus: 235.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 13.8" "Region enhanced" "Detected in many" "hypothalamus: 70.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA067560, HPA069756, HPA077424" Approved Supported Uncertain "Nucleoplasm,Nuclear membrane,Nucleoli" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 65: Non-specific - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" 54 Nucleoplasm "Nuclear membrane, Nucleoli" "HPA067560: , HPA069756: , HPA077424: " "unprognostic (3.33e-2)" "unprognostic (1.51e-2)" "unprognostic (1.61e-2)" "unprognostic (4.77e-3)" "unprognostic (3.37e-1)" "unprognostic (9.71e-3)" "unprognostic (1.83e-3)" "unprognostic (1.40e-2)" "unprognostic (4.54e-2)" "unprognostic (6.52e-3)" "unprognostic (1.34e-1)" "unprognostic (3.54e-2)" "unprognostic (2.83e-2)" "unprognostic (2.83e-1)" "unprognostic (3.33e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (3.69e-2)" "unprognostic (2.40e-2)" "unprognostic (4.15e-2)" "unprognostic (1.73e-1)" "unprognostic (2.24e-1)" "unprognostic (1.32e-1)" ECH1 HPXEL ENSG00000104823 "Enoyl-CoA hydratase 1" Q13011 19 38815422-38831841 "Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 769.1;skeletal muscle: 904.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 384.9;Extravillous trophoblasts: 201.6;Migrating cytotrophoblasts: 332.5;Syncytiotrophoblasts: 278.4" "Cell type enhanced" "Detected in all" "Trophoblast cells: 384.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 476662414.4" "Group enriched" "Detected in all" "heart muscle: 855693917.2;kidney: 368638772.0;liver: 409188957.4;skeletal muscle: 220856495.3" "HPA002907, HPA005835" Supported Supported Supported Mitochondria No No 1300000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 29 Mitochondria "HPA002907: , HPA005835: " "unprognostic (1.59e-1)" "unprognostic (4.73e-2)" "potential prognostic unfavorable (4.54e-5)" "unprognostic (1.59e-1)" "unprognostic (1.34e-1)" "unprognostic (8.66e-2)" "unprognostic (1.49e-1)" "unprognostic (8.56e-2)" "unprognostic (1.70e-1)" "unprognostic (3.37e-1)" "potential prognostic favorable (5.12e-8)" "unprognostic (7.17e-3)" "unprognostic (4.06e-3)" "unprognostic (1.84e-1)" "unprognostic (9.17e-2)" "unprognostic (4.18e-3)" "unprognostic (6.08e-3)" "unprognostic (4.05e-2)" "unprognostic (1.65e-2)" "unprognostic (1.34e-2)" "unprognostic (2.67e-1)" "unprognostic (3.80e-2)" "unprognostic (2.45e-1)" "unprognostic (1.90e-1)" "unprognostic (2.58e-1)" "unprognostic (1.43e-1)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (2.93e-4)" "unprognostic (1.15e-1)" "unprognostic (9.45e-2)" "unprognostic (4.82e-2)" ECHDC1 dJ351K20.2 ENSG00000093144 "Ethylmalonyl-CoA decarboxylase 1" Q9NTX5 6 127288712-127343609 "Enzymes, Plasma proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 310.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubules: 112042328.1" "Low tissue specificity" "Detected in all" "HPA035445, HPA035446" Uncertain Approved Vesicles NA NA 33000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 89: Adipocytes - Lipid metabolism" 2 Vesicles "HPA035445: , HPA035446: " "unprognostic (3.73e-1)" "unprognostic (1.22e-1)" "unprognostic (3.92e-2)" "unprognostic (6.44e-3)" "unprognostic (2.25e-3)" "unprognostic (1.95e-2)" "unprognostic (1.27e-1)" "unprognostic (2.52e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (5.35e-5)" "potential prognostic favorable (9.33e-7)" "unprognostic (3.84e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (4.86e-3)" "unprognostic (4.55e-2)" "unprognostic (4.05e-2)" "unprognostic (8.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.74e-1)" "unprognostic (1.76e-1)" "unprognostic (6.41e-2)" "unprognostic (3.24e-1)" "unprognostic (9.02e-2)" "unprognostic (2.12e-2)" "unprognostic (2.05e-1)" "unprognostic (4.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.37e-1)" "unprognostic (3.06e-1)" "unprognostic (1.61e-2)" ECI1 DCI ENSG00000167969 "Enoyl-CoA delta isomerase 1" P42126 16 2239402-2252300 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 298.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Large ducts: 424860274.6" "Tissue enhanced" "Detected in all" "heart muscle: 475249586.1" "HPA041746, HPA043227" Enhanced Enhanced Mitochondria NA NA 3100000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" Mitochondria "HPA041746: , HPA043227: " "unprognostic (2.60e-2)" "unprognostic (2.12e-1)" "potential prognostic favorable (3.16e-4)" "unprognostic (3.14e-2)" "unprognostic (3.87e-2)" "unprognostic (1.25e-1)" "unprognostic (4.08e-3)" "unprognostic (3.70e-2)" "potential prognostic favorable (5.89e-4)" "potential prognostic favorable (6.86e-6)" "unprognostic (4.10e-2)" "potential prognostic favorable (3.88e-4)" "unprognostic (5.50e-3)" "unprognostic (2.76e-2)" "unprognostic (5.68e-2)" "unprognostic (2.27e-1)" "unprognostic (2.13e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-1)" "unprognostic (1.41e-2)" "unprognostic (8.46e-2)" "unprognostic (1.19e-1)" "unprognostic (2.53e-2)" "unprognostic (3.99e-2)" "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "unprognostic (5.06e-2)" "unprognostic (2.46e-1)" "unprognostic (5.57e-2)" "unprognostic (1.38e-1)" ECPAS "ECM29, FLJ22036, KIAA0368" ENSG00000136813 "Ecm29 proteasome adaptor and scaffold" Q5VYK3 9 111360685-111484745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 227.2" "Cell type enhanced" "Detected in all" "Myonuclei: 505.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA021646, HPA059795" Uncertain Supported Nucleoplasm Yes No 15000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 91 Nucleoplasm "HPA021646: , HPA059795: " "unprognostic (2.84e-1)" "unprognostic (3.73e-2)" "unprognostic (5.71e-2)" "unprognostic (1.58e-1)" "unprognostic (2.58e-3)" "unprognostic (1.63e-1)" "unprognostic (3.20e-2)" "unprognostic (8.27e-2)" "unprognostic (3.53e-1)" "potential prognostic favorable (1.09e-8)" "unprognostic (7.30e-3)" "unprognostic (5.15e-2)" "unprognostic (8.61e-3)" "unprognostic (1.37e-3)" "unprognostic (1.79e-1)" "unprognostic (5.59e-2)" "unprognostic (1.79e-1)" "unprognostic (8.05e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (4.57e-1)" "unprognostic (6.08e-2)" "unprognostic (5.08e-2)" "unprognostic (3.66e-1)" "unprognostic (4.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.36e-1)" "unprognostic (3.38e-1)" "unprognostic (4.79e-2)" ECT2 ARHGEF31 ENSG00000114346 "Epithelial cell transforming 2" Q9H8V3 3 172750682-172821474 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Neurogenesis, Protein transport, Transport" "Guanine-nucleotide releasing factor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 134.6;Early primary spermatocytes: 61.0;Erythrocyte progenitors: 65.9;Gastric progenitor cells: 100.0;Monocyte progenitors: 126.4;Neutrophil progenitors: 85.4;Respiratory deuterosomal cells: 61.2" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 126.4;Neuronal cells: 134.6;Proliferating cells: 100.0" "Cell type enriched" "Detected in all" 4 "endothelial cell: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1878 "Granulosa cells: 187755.0" "Tissue enriched" "Detected in single" 210 "intestine: 20968.8" "HPA036363, HPA053261" Enhanced Nucleoplasm,Cytosol No Yes "Cluster 32: Basophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 27: Non-specific - Cell proliferation" 67 Nucleoplasm Cytosol "HPA036363: , HPA053261: " "unprognostic (2.00e-2)" "unprognostic (1.02e-1)" "unprognostic (4.81e-2)" "unprognostic (1.23e-1)" "unprognostic (3.18e-2)" "unprognostic (1.30e-1)" "unprognostic (1.50e-1)" "unprognostic (3.64e-2)" "unprognostic (2.06e-2)" "unprognostic (1.72e-3)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.88e-6)" "unprognostic (3.32e-2)" "validated prognostic unfavorable (2.93e-6)" "validated prognostic unfavorable (1.66e-6)" "potential prognostic unfavorable (4.55e-7)" "unprognostic (2.77e-3)" "unprognostic (1.38e-2)" "unprognostic (3.85e-2)" "unprognostic (1.02e-1)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (3.33e-2)" "unprognostic (3.60e-2)" "unprognostic (1.25e-1)" "unprognostic (1.05e-1)" "unprognostic (7.28e-2)" "unprognostic (4.09e-3)" "unprognostic (3.05e-1)" "unprognostic (3.33e-2)" "unprognostic (3.05e-1)" EDN1 ET1 ENSG00000078401 "Endothelin 1" P05305 6 12290361-12297194 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Vasoactive, Vasoconstrictor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 41.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 226.1;Basal keratinocytes: 170.8;Breast secretory cells: 252.1;Colonocytes: 167.4;Endometrial ciliated cells: 173.4;Endometrial glandular cells: 279.9;Endometrial luminal cells: 242.6;Endometrial secretory cells: 224.3;Enteric stem cells: 294.4;Enteric transient amplifying cells: 170.1;Enterocytes: 141.9;Epididymal basal cells: 356.3;Epididymal efferent duct absorptive cells: 211.6;Pancreatic duct cells: 256.3;Vascular endothelial cells: 182.0" "Cell type enhanced" "Detected in many" "Basal cells: 356.3;Ductal cells: 256.3;Glandular cells: 279.9;Secretory cells: 252.1;Stem cells: 294.4" "Cell type enriched" "Detected in many" 24 "endothelial cell: 140.5" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 51.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 4.9" "Lineage enriched" "Detected in single" 6 "monocytes: 4.9" "Cancer enhanced" "Detected in many" "testis cancer: 108.1" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031976, HPA031978, CAB032500, CAB037291" Approved Approved "Golgi apparatus" "Secreted to blood" Other NA Yes 9740 "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Golgi apparatus" "CAB032500: , CAB037291: , HPA031976: , HPA031978: " "unprognostic (2.12e-1)" "unprognostic (1.41e-2)" "unprognostic (2.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (6.91e-3)" "unprognostic (3.35e-1)" "unprognostic (1.20e-1)" "unprognostic (1.42e-1)" "unprognostic (9.57e-3)" "validated prognostic favorable (1.94e-5)" "validated prognostic favorable (1.95e-5)" "unprognostic (1.65e-1)" "unprognostic (4.91e-2)" "unprognostic (7.88e-3)" "unprognostic (3.91e-1)" "unprognostic (2.86e-1)" "unprognostic (1.62e-3)" "unprognostic (4.40e-2)" "unprognostic (2.26e-2)" "unprognostic (1.15e-2)" "unprognostic (1.80e-2)" "unprognostic (1.43e-1)" "unprognostic (3.27e-1)" "unprognostic (1.31e-2)" "unprognostic (4.43e-3)" "unprognostic (1.13e-1)" "unprognostic (1.15e-1)" "unprognostic (1.54e-1)" "unprognostic (8.11e-2)" "unprognostic (1.22e-1)" EEF1A1 "EE1A1, EEF1A, EF1A, EF1A1, EF1alpha1, LENG7" ENSG00000156508 "Eukaryotic translation elongation factor 1 alpha 1" P68104 6 73489308-73525587 "Cancer-related genes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis, Transcription, Transcription regulation" "Elongation factor, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enteric stem cells: 5147.5;Enteric transient amplifying cells: 3989.8;Epididymal basal cells: 3857.6;Epididymal efferent duct absorptive cells: 4827.8;Epididymal principal cells: 3303.8;Paneth cells: 4010.5" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "leukocyte: 147.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 617664301.2" "Low tissue specificity" "Detected in many" "HPA051759, HPA053862, HPA056990" Supported Supported Cytosol NA NA 76000000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 158 Cytosol "HPA051759: , HPA053862: , HPA056990: " "unprognostic (1.27e-2)" "unprognostic (1.40e-1)" "unprognostic (1.79e-1)" "unprognostic (1.77e-2)" "unprognostic (8.02e-2)" "unprognostic (7.54e-3)" "unprognostic (1.71e-2)" "unprognostic (9.77e-2)" "unprognostic (5.07e-2)" "unprognostic (2.66e-1)" "validated prognostic favorable (5.22e-5)" "validated prognostic favorable (6.73e-4)" "unprognostic (7.90e-2)" "potential prognostic unfavorable (1.24e-6)" "unprognostic (6.25e-3)" "unprognostic (3.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.45e-1)" "unprognostic (7.02e-2)" "unprognostic (1.16e-1)" "unprognostic (5.60e-3)" "unprognostic (2.08e-1)" "unprognostic (6.81e-2)" "unprognostic (2.04e-1)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (1.36e-1)" "unprognostic (9.60e-2)" "unprognostic (4.38e-1)" "unprognostic (4.33e-1)" "unprognostic (6.98e-2)" EEF1A2 "EEF1AL, HS1, STN, STNL" ENSG00000101210 "Eukaryotic translation elongation factor 1 alpha 2" Q05639 20 63488013-63499239 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor, Hydrolase" "Autism spectrum disorder, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 722.2;skeletal muscle: 1827.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 113.4;Brain inhibitory neurons: 77.9;Corticotrophs: 84.1;Gonadotrophs: 74.4;Myonuclei: 71.1;Other brain neurons: 133.8;Pancreatic islet cells: 167.5;Retinal amacrine cells: 60.1;Retinal bipolar cells: 83.7;Retinal horizontal cells: 154.3;Thymic myoid cells: 613.2" "Cell type enhanced" "Detected in many" "Neuronal cells: 154.3;Pancreatic islet cells: 167.5;Stromal cells: 613.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB034019, HPA051759, HPA053862, HPA056990" Approved Approved Cytosol NA NA 44000000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 60 Cytosol "CAB034019: , HPA051759: , HPA053862: , HPA056990: " "unprognostic (7.36e-2)" "unprognostic (2.95e-2)" "unprognostic (3.43e-1)" "unprognostic (9.03e-2)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (1.94e-2)" "unprognostic (4.71e-3)" "unprognostic (2.06e-1)" "unprognostic (5.90e-3)" "unprognostic (1.86e-2)" "unprognostic (5.67e-3)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (4.89e-1)" "unprognostic (1.95e-2)" "unprognostic (2.37e-1)" "unprognostic (4.03e-2)" "unprognostic (1.52e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-2)" "unprognostic (7.52e-3)" "unprognostic (1.11e-2)" "unprognostic (1.66e-3)" "unprognostic (3.07e-1)" "unprognostic (4.09e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (3.49e-3)" "unprognostic (1.52e-1)" "unprognostic (9.06e-3)" "potential prognostic unfavorable (2.26e-4)" EEF1AKMT2 "C10orf138, Efm4, METTL10" ENSG00000203791 "EEF1A lysine methyltransferase 2" Q5JPI9 10 124748149-124791887 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 12.6;Late primary spermatocytes: 35.1" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 35.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Fallopian tube cells: 251904.4;Granulosa cells: 349547.0;Large ducts: 269161.9;Oocytes: 170690.3" "Tissue enriched" "Detected in many" "intestine: 4410668.9" HPA050138 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Nucleoplasm, Cytosol" "HPA050138: " "unprognostic (4.18e-2)" "unprognostic (2.50e-1)" "unprognostic (4.88e-3)" "unprognostic (4.34e-2)" "unprognostic (7.68e-2)" "unprognostic (1.32e-1)" "unprognostic (6.64e-3)" "unprognostic (3.40e-1)" "unprognostic (7.17e-2)" "potential prognostic favorable (5.38e-5)" "unprognostic (3.14e-2)" "unprognostic (3.32e-1)" "unprognostic (8.13e-3)" "unprognostic (2.23e-3)" "unprognostic (5.67e-2)" "unprognostic (2.16e-3)" "unprognostic (1.15e-3)" "unprognostic (3.30e-1)" "unprognostic (2.93e-2)" "unprognostic (5.23e-1)" "unprognostic (1.21e-2)" "unprognostic (1.53e-3)" "unprognostic (1.01e-1)" "unprognostic (3.47e-2)" "unprognostic (2.18e-2)" "unprognostic (3.50e-1)" "unprognostic (4.13e-1)" "potential prognostic unfavorable (9.02e-5)" "unprognostic (2.20e-1)" EEF1AKMT3 "DKFZP586D0919, FAM119B, METTL21B" ENSG00000123427 "EEF1A lysine methyltransferase 3" Q96AZ1 12 57771492-57782541 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 6.2;Early spermatids: 12.0;Epicardial cells: 27.3;Late spermatids: 23.1" "Group enriched" "Detected in some" 4 "Barrier epithelial cells: 27.3;Spermatogenic cell types: 23.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Stomach - Chief cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043020, HPA045492" Uncertain Approved "Nucleoplasm,Mitotic chromosome,Centrosome" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 176 Centrosome "Nucleoplasm, Mitotic chromosome" "HPA043020: , HPA045492: " "unprognostic (1.21e-2)" "unprognostic (1.34e-1)" "unprognostic (3.39e-2)" "unprognostic (1.04e-1)" "unprognostic (2.63e-1)" "unprognostic (3.73e-1)" "unprognostic (1.07e-1)" "unprognostic (1.84e-1)" "unprognostic (1.27e-3)" "unprognostic (1.56e-3)" "unprognostic (1.47e-2)" "unprognostic (1.61e-1)" "unprognostic (3.30e-3)" "unprognostic (9.25e-2)" "unprognostic (5.25e-3)" "unprognostic (1.20e-1)" "unprognostic (6.64e-2)" "unprognostic (3.61e-2)" "unprognostic (8.95e-2)" "unprognostic (2.18e-1)" "unprognostic (6.78e-2)" "unprognostic (2.78e-1)" "unprognostic (1.92e-2)" "unprognostic (3.48e-2)" "unprognostic (9.51e-3)" "unprognostic (1.32e-1)" "unprognostic (6.34e-2)" "unprognostic (9.99e-3)" "unprognostic (1.90e-1)" EEF2 "EEF-2, EF2" ENSG00000167658 "Eukaryotic translation elongation factor 2" P13639 19 3976056-3985463 "Cancer-related genes, Disease related genes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor, Hydrolase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 2701.8;Pancreatic acinar cells: 2575.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB007795, HPA040534, HPA057351" Enhanced Approved "Plasma membrane,Cytosol" NA NA 25000000 "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 47: Endothelial cells - Vasculature" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 66 "Plasma membrane, Cytosol" "CAB007795: , HPA040534: , HPA057351: " "unprognostic (8.33e-2)" "unprognostic (1.60e-2)" "unprognostic (5.34e-2)" "unprognostic (5.62e-3)" "unprognostic (2.09e-1)" "unprognostic (2.01e-1)" "unprognostic (9.38e-2)" "unprognostic (7.69e-2)" "unprognostic (1.64e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (2.48e-4)" "unprognostic (6.19e-3)" "unprognostic (2.53e-1)" "unprognostic (2.47e-3)" "unprognostic (4.40e-3)" "unprognostic (3.01e-1)" "unprognostic (1.02e-1)" "unprognostic (2.21e-1)" "unprognostic (3.96e-1)" "unprognostic (1.12e-2)" "unprognostic (1.18e-2)" "unprognostic (3.52e-2)" "unprognostic (1.40e-2)" "unprognostic (1.20e-1)" "unprognostic (2.43e-2)" "unprognostic (1.93e-1)" "unprognostic (2.63e-1)" "unprognostic (5.65e-2)" "unprognostic (1.15e-1)" "unprognostic (9.39e-2)" "potential prognostic favorable (3.75e-4)" EFCAB12 C3orf25 ENSG00000172771 "EF-hand calcium binding domain 12" Q6NXP0 3 129401321-129428651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 10.2;fallopian tube: 18.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 51.9;Early spermatids: 40.7;Endometrial ciliated cells: 61.1;Ependymal cells: 130.6;Epididymal efferent duct ciliated cells: 35.3;Fallopian tube ciliated cells: 72.0;Late spermatids: 29.9;Respiratory ciliated cells: 91.9" "Group enriched" "Detected in many" 4 "Ciliated cells: 130.6;Spermatogenic cell types: 40.7" "Cell type enriched" "Detected in many" 4 "ependymal cell: 148.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.2" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 11.8" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 18 "fallopian tube: 1800.2" "HPA037694, HPA057532" Uncertain Supported Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 60: Prostate cancer - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 Nucleoplasm "Nuclear bodies, Midbody ring" "HPA037694: , HPA057532: " "unprognostic (2.09e-2)" "unprognostic (6.33e-2)" "unprognostic (7.65e-2)" "unprognostic (7.74e-2)" "unprognostic (2.30e-2)" "unprognostic (6.77e-2)" "unprognostic (8.90e-2)" "unprognostic (3.16e-3)" "unprognostic (5.26e-1)" "unprognostic (3.03e-1)" EFCAB2 "CFAP200, DRC8, MGC12458" ENSG00000203666 "EF-hand calcium binding domain 2" Q5VUJ9 1 244969682-245127164 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 564.8;Ependymal cells: 865.0;Fallopian tube ciliated cells: 471.8;Myonuclei: 558.6;Respiratory ciliated cells: 700.7" "Cell type enhanced" "Detected in all" "Ciliated cells: 865.0;Myocytes: 558.6" "Cell type enhanced" "Detected in all" "ependymal cell: 878.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 5.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 817239.1" "Tissue enriched" "Detected in some" "fallopian tube: 611550.2" HPA031206 Approved Approved "Plasma membrane,Mitochondria,Cytosol,Mid piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Plasma membrane, Cytosol, Mid piece" Mitochondria "HPA031206: " "unprognostic (9.54e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (9.75e-2)" "unprognostic (4.43e-2)" "unprognostic (1.91e-1)" "unprognostic (6.79e-2)" "unprognostic (2.10e-1)" "unprognostic (2.19e-1)" "unprognostic (2.44e-2)" "unprognostic (1.21e-1)" "unprognostic (3.44e-2)" "unprognostic (1.80e-1)" "unprognostic (2.15e-3)" "unprognostic (8.71e-2)" "unprognostic (3.51e-2)" "unprognostic (1.35e-1)" "unprognostic (8.36e-3)" "unprognostic (2.27e-1)" "unprognostic (2.35e-1)" "unprognostic (8.34e-3)" "unprognostic (2.35e-2)" "unprognostic (2.73e-3)" "unprognostic (2.29e-2)" "unprognostic (3.48e-2)" "unprognostic (1.62e-1)" "unprognostic (2.85e-2)" "unprognostic (1.03e-1)" "unprognostic (1.91e-1)" "unprognostic (6.90e-3)" "unprognostic (1.38e-1)" EFCAB6 "dJ185D5.1, DJBP, FLJ23588, HSCBCIP1, KIAA1672" ENSG00000186976 "EF-hand calcium binding domain 6" Q5THR3 22 43528744-43812337 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "fallopian tube: 7.2;testis: 22.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 305.6;Early spermatids: 473.2;Endometrial ciliated cells: 226.3;Ependymal cells: 733.1;Fallopian tube ciliated cells: 223.7;Late spermatids: 802.6;Respiratory ciliated cells: 516.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 733.1;Spermatogenic cell types: 802.6" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 239.0;ependymal cell: 804.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 72535 "Fallopian tube cells: 7253476.9" "Tissue enriched" "Detected in single" 33621 "fallopian tube: 3362086.1" "HPA003098, HPA018946" Supported "Nucleoplasm,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 Nucleoplasm "Mid piece, Principal piece" "HPA003098: , HPA018946: " "unprognostic (1.29e-1)" "unprognostic (3.38e-1)" "unprognostic (3.01e-1)" "validated prognostic favorable (4.00e-8)" "validated prognostic favorable (1.06e-5)" "unprognostic (4.02e-2)" "unprognostic (5.37e-2)" "unprognostic (2.51e-3)" "unprognostic (1.01e-2)" EFHB "CFAP21, FLJ25200" ENSG00000163576 "EF-hand domain family member B" Q8N7U6 3 19879472-19947025 "Predicted intracellular proteins" "Calcium transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 16.0;testis: 14.5" "Cell type enhanced" "Detected in many" "Early spermatids: 57.0;Endometrial ciliated cells: 81.5;Ependymal cells: 136.1;Epididymal efferent duct ciliated cells: 176.3;Fallopian tube ciliated cells: 152.0;Late primary spermatocytes: 96.5;Respiratory ciliated cells: 152.2" "Group enriched" "Detected in many" 9 "Ciliated cells: 176.3;Spermatogenic cell types: 96.5" "Cell type enriched" "Detected in many" 7 "ependymal cell: 166.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 2.7;Kidney cancer: 4.1" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 44489 "Fallopian tube cells: 4448876.2" "Tissue enriched" "Detected in single" 36363 "fallopian tube: 3636321.1" HPA034835 Approved "Nuclear bodies,Vesicles,Cytosol,Connecting piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 Cytosol "Nuclear bodies, Vesicles, Connecting piece" "HPA034835: " "unprognostic (1.50e-1)" "unprognostic (3.96e-3)" "unprognostic (2.95e-1)" "unprognostic (8.04e-3)" "unprognostic (3.09e-1)" "unprognostic (4.42e-1)" "unprognostic (1.26e-1)" "unprognostic (2.19e-2)" EFHC1 "EJM, EJM1, FLJ10466, POC9, RIB72" ENSG00000096093 "EF-hand domain containing 1" Q5JVL4 6 52362123-52529886 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 32.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 352.3;Endometrial ciliated cells: 432.2;Ependymal cells: 456.8;Epididymal efferent duct ciliated cells: 481.4;Fallopian tube ciliated cells: 483.2;Respiratory ciliated cells: 663.6" "Cell type enhanced" "Detected in all" "Ciliated cells: 663.6" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 353.8;ependymal cell: 505.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 36698634.2" "Tissue enriched" "Detected in some" "fallopian tube: 64074945.4" HPA035307 Approved Uncertain "Plasma membrane,Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 64 "Plasma membrane, Mid piece, Principal piece, End piece" "Cytosol, Equatorial segment" "HPA035307: " "unprognostic (5.48e-2)" "unprognostic (1.60e-2)" "unprognostic (2.26e-2)" "unprognostic (1.83e-1)" "unprognostic (5.58e-2)" "unprognostic (9.94e-2)" "unprognostic (2.85e-1)" "unprognostic (7.40e-2)" "unprognostic (1.55e-1)" "unprognostic (7.01e-2)" "unprognostic (6.19e-2)" "unprognostic (8.55e-2)" "unprognostic (5.74e-2)" "unprognostic (7.51e-2)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (2.40e-2)" "unprognostic (2.74e-1)" "unprognostic (2.18e-1)" "unprognostic (2.25e-2)" "unprognostic (7.92e-3)" "unprognostic (2.18e-2)" "unprognostic (1.29e-1)" "unprognostic (6.04e-2)" "unprognostic (9.71e-2)" "unprognostic (1.46e-1)" "unprognostic (1.11e-1)" "unprognostic (1.58e-1)" "unprognostic (4.36e-2)" "unprognostic (1.54e-1)" EFHD1 FLJ13612 ENSG00000115468 "EF-hand domain family member D1" Q9BUP0 2 232606057-232682776 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 313.4;brain: 324.6" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 452.1;Breast lactating cells: 304.7;Distal convoluted tubule cells: 262.3;Hepatocytes: 174.2;Loop of henle epithelial cells: 281.4;Migrating cytotrophoblasts: 238.9;Oligodendrocytes: 216.3;Pericytes: 187.4;Renal collecting duct intercalated cells: 281.7;Syncytiotrophoblasts: 426.3;Vascular smooth muscle cells: 259.2" "Cell type enhanced" "Detected in many" "Ductal cells: 281.7;Luminal cells: 452.1;Renal nephron cells: 281.4;Secretory cells: 304.7;Trophoblast cells: 426.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 275.2;pericyte: 271.6;vascular associated smooth muscle cell: 190.6" "Group enriched" "Detected in all" 4 "Breast Invasive Carcinoma (TCGA): 314.4;Kidney Chromophobe (TCGA): 235.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in many" 5 "breast cancer: 172.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 44423989.8" "Low tissue specificity" "Detected in many" "HPA049331, HPA056959" Enhanced Supported "Nucleoli fibrillar center,Golgi apparatus" No NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 12 "Golgi apparatus" "Nucleoli fibrillar center" "HPA049331: , HPA056959: " "unprognostic (5.17e-2)" "unprognostic (5.49e-3)" "unprognostic (7.17e-2)" "unprognostic (7.30e-3)" "unprognostic (2.75e-2)" "unprognostic (9.60e-2)" "unprognostic (1.55e-1)" "unprognostic (2.14e-1)" "unprognostic (7.86e-2)" "unprognostic (4.20e-3)" "validated prognostic favorable (5.51e-6)" "validated prognostic favorable (4.24e-4)" "unprognostic (3.65e-3)" "unprognostic (9.24e-2)" "unprognostic (4.98e-3)" "unprognostic (1.78e-1)" "unprognostic (4.69e-3)" "unprognostic (1.32e-2)" "unprognostic (1.89e-1)" "unprognostic (8.77e-2)" "unprognostic (7.88e-2)" "unprognostic (8.20e-2)" "unprognostic (1.19e-1)" "unprognostic (7.45e-2)" "unprognostic (1.12e-2)" "unprognostic (2.83e-2)" "unprognostic (4.23e-2)" "unprognostic (1.35e-2)" "unprognostic (2.26e-1)" "unprognostic (3.95e-2)" "unprognostic (1.24e-2)" EFHD2 MGC4342 ENSG00000142634 "EF-hand domain family member D2" Q96C19 1 15409888-15430339 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 290.1;Extravillous trophoblasts: 304.5;Foveolar cells: 395.2;Hofbauer cells: 289.6;Late spermatids: 355.1;monocytes: 406.3;Neutrophils: 927.6;Pancreatic acinar cells: 455.3;Urothelial cells: 276.9" "Cell type enhanced" "Detected in many" "Neutrophils: 927.6" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 185.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 133.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Macrophages, Prostate - Urothelial cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA048961 Enhanced Approved Cytosol No No 250000 "Cluster 7: Non-specific - Innate immune response" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Cytosol "HPA048961: " "unprognostic (9.09e-2)" "unprognostic (2.78e-3)" "unprognostic (2.32e-2)" "unprognostic (3.43e-2)" "unprognostic (1.15e-1)" "unprognostic (1.31e-1)" "unprognostic (1.75e-2)" "unprognostic (7.09e-2)" "unprognostic (2.64e-2)" "unprognostic (2.02e-2)" "unprognostic (1.46e-2)" "unprognostic (8.90e-2)" "unprognostic (8.03e-2)" "unprognostic (6.90e-2)" "unprognostic (1.17e-2)" "potential prognostic unfavorable (9.87e-4)" "unprognostic (1.35e-2)" "unprognostic (6.25e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (2.15e-2)" "unprognostic (1.06e-1)" "unprognostic (3.38e-1)" "unprognostic (4.98e-2)" "unprognostic (7.92e-3)" "unprognostic (3.87e-1)" "unprognostic (1.68e-1)" "unprognostic (7.92e-2)" "unprognostic (7.71e-2)" "potential prognostic favorable (7.91e-4)" "unprognostic (1.37e-1)" EFNA2 "ELF-1, EPLG6, LERK6" ENSG00000099617 "Ephrin A2" O43921 19 1285873-1301431 "Cancer-related genes, Predicted intracellular proteins, RAS pathway related proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "gallbladder: 3.3;intestine: 11.6;liver: 12.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 49.1;Colonocytes: 68.3;Enteric stem cells: 29.2;Enteric transient amplifying cells: 39.2;Enterocytes: 60.0;Epididymal basal cells: 36.2;Gastric progenitor cells: 19.2;Goblet cells: 20.9;Paneth cells: 23.2" "Cell type enhanced" "Detected in many" "Basal cells: 36.2;Enterocytes: 68.3;Proliferating cells: 39.2;Secretory gland support: 49.1" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 14.9" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 16.2;Rectum Adenocarcinoma (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.0" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA067567 Approved Mitochondria,Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 77: Intestine - Digestion" "Cluster 38: Sub-cortical - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 33 "Mitochondria, Cytosol" "HPA067567: " "unprognostic (3.03e-2)" "unprognostic (1.13e-2)" "unprognostic (7.54e-3)" "potential prognostic favorable (9.43e-4)" "unprognostic (1.10e-1)" "unprognostic (2.56e-2)" "unprognostic (6.25e-2)" "unprognostic (7.93e-2)" "unprognostic (5.19e-3)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (1.00e-2)" "unprognostic (3.02e-2)" "unprognostic (2.90e-1)" "unprognostic (1.55e-2)" "unprognostic (2.64e-1)" "unprognostic (6.90e-2)" "unprognostic (7.22e-2)" "unprognostic (2.09e-2)" EFS "CASS3, EFS1, EFS2, HEFS, SIN" ENSG00000100842 "Embryonal Fyn-associated substrate" O43281 14 23356403-23365752 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 36.2;Breast lactating cells: 35.4;Esophageal apical cells: 33.2;Esophageal suprabasal cells: 39.9;Hepatic stellate cells: 38.7;Oligodendrocyte progenitor cells: 46.6;Oligodendrocytes: 63.5;Schwann cells: 50.4" "Cell type enhanced" "Detected in many" "Glial cells: 63.5" "Cell type enhanced" "Detected in many" "oligodendrocyte: 79.4;oligodendrocyte precursor cell: 50.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Keratinocytes: 881027.2;Pancreas epithelial cells: 510201.0" "Group enriched" "Detected in some" "ovary: 1782350.0;salivary gland: 1111329.5" "HPA001581, HPA001790" Approved Uncertain Nucleoplasm,Cytosol No NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 85: Squamous epithelial cells - Keratinization" 16 Nucleoplasm Cytosol "HPA001581: , HPA001790: " "unprognostic (1.21e-1)" "unprognostic (2.26e-2)" "unprognostic (3.32e-2)" "unprognostic (2.55e-2)" "unprognostic (1.44e-2)" "unprognostic (2.77e-1)" "unprognostic (8.75e-2)" "potential prognostic favorable (2.02e-4)" "unprognostic (7.53e-2)" "unprognostic (5.54e-3)" "unprognostic (1.04e-1)" "unprognostic (5.11e-2)" "unprognostic (1.68e-1)" "unprognostic (4.02e-2)" "unprognostic (1.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.62e-2)" "unprognostic (8.46e-2)" "unprognostic (1.54e-1)" "unprognostic (3.11e-1)" "unprognostic (2.19e-1)" "unprognostic (2.12e-2)" "unprognostic (2.05e-1)" "unprognostic (1.53e-1)" "unprognostic (2.95e-2)" "unprognostic (7.58e-3)" "unprognostic (1.23e-1)" "unprognostic (3.58e-1)" "unprognostic (1.47e-1)" EFTUD2 "SNRNP116, Snrp116, Snu114, U5-116KD" ENSG00000108883 "Elongation factor Tu GTP binding domain containing 2" Q15029 17 44849948-44899445 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA022021 Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 190000 "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 326 Nucleoplasm "Vesicles, Cytosol" "HPA022021: " "unprognostic (8.50e-3)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (1.09e-1)" "unprognostic (1.89e-1)" "unprognostic (3.31e-3)" "unprognostic (2.54e-1)" "unprognostic (1.48e-1)" "unprognostic (2.43e-3)" "unprognostic (3.24e-2)" "potential prognostic unfavorable (3.75e-4)" "potential prognostic favorable (4.93e-5)" "unprognostic (4.89e-2)" "unprognostic (1.38e-1)" "validated prognostic unfavorable (3.43e-5)" "validated prognostic unfavorable (7.07e-5)" "unprognostic (4.76e-3)" "unprognostic (2.99e-3)" "unprognostic (1.15e-1)" "unprognostic (5.83e-3)" "unprognostic (1.09e-1)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "unprognostic (3.11e-3)" "unprognostic (2.13e-1)" "unprognostic (1.17e-2)" "unprognostic (4.20e-2)" "unprognostic (1.57e-1)" "unprognostic (1.01e-1)" "unprognostic (2.68e-1)" "unprognostic (2.04e-1)" "unprognostic (3.04e-2)" EGFR "ERBB, ERBB1, ERRP" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins, Transporters" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 61.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1190.3;Fibro-adipogenic progenitors: 1097.7;Myosatellite cells: 789.2;Respiratory basal cells: 935.5;Syncytiotrophoblasts: 1481.8" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 1097.7;Trophoblast cells: 1481.8" "Cell type enhanced" "Detected in many" "astrocyte: 363.8;Bergmann glia: 419.5" "Cancer enriched" "Detected in all" 4 "Glioblastoma Multiforme (TCGA): 324.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 22199260.0" "Low tissue specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534, CAB080313, CAB080314, CAB080473, CAB080474, CAB080475, CAB080506, CAB080507, CAB080508, CAB080509, CAB080510, CAB080511, CAB080513" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions,Primary cilium,Basal body,Mid piece,Principal piece,End piece" "Secreted to blood" Receptor NA NA 4740000 19000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 926 "Golgi apparatus, Plasma membrane" "Cell Junctions, Primary cilium, Basal body, Mid piece, Principal piece, End piece" "CAB000035: , CAB068186: , CAB073534: , CAB080313: , CAB080314: , CAB080473: , CAB080474: , CAB080475: , CAB080506: , CAB080507: , CAB080508: , CAB080509: , CAB080510: , CAB080511: , CAB080513: , HPA001200: , HPA018530: " "unprognostic (7.14e-2)" "unprognostic (2.28e-2)" "unprognostic (9.66e-2)" "unprognostic (2.14e-3)" "unprognostic (9.48e-2)" "unprognostic (9.42e-2)" "unprognostic (1.44e-1)" "unprognostic (2.07e-2)" "unprognostic (3.73e-2)" "unprognostic (2.68e-3)" "potential prognostic favorable (8.23e-5)" "unprognostic (1.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.35e-1)" "unprognostic (1.01e-2)" "unprognostic (4.78e-2)" "unprognostic (1.38e-1)" "unprognostic (6.90e-2)" "unprognostic (2.25e-1)" "unprognostic (3.35e-3)" "unprognostic (2.91e-1)" "unprognostic (5.73e-3)" "potential prognostic unfavorable (4.42e-5)" "unprognostic (1.11e-1)" "unprognostic (3.51e-2)" "unprognostic (1.84e-1)" "unprognostic (1.92e-2)" "unprognostic (4.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.14e-2)" "unprognostic (9.81e-2)" EGR1 "225, AT225, G0S30, KROX-24, NGFI-A, TIS8, ZIF-268" ENSG00000120738 "Early growth response 1" P18146 5 138465479-138469303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1777.0;Medullary thymic epithelial cells: 1219.3;Ovarian stromal cells: 1277.4;Thymic myoid cells: 1354.2" "Cell type enhanced" "Detected in all" "Basal cells: 1777.0" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 81.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 273.3" "Immune cell enhanced" "Detected in some" "neutrophil: 7.1" "Group enriched" "Detected in many" 7 "granulocytes: 7.1;monocytes: 3.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 418 "Neurons: 41771.7" "Not detected" "Not detected" "CAB019427, HPA029937, HPA029938" Supported Enhanced Nucleoplasm No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 Nucleoplasm "CAB019427: , HPA029937: , HPA029938: " "unprognostic (2.84e-2)" "unprognostic (7.42e-2)" "unprognostic (5.87e-2)" "unprognostic (4.23e-2)" "unprognostic (1.95e-2)" "unprognostic (2.03e-1)" "unprognostic (1.13e-1)" "unprognostic (5.12e-2)" "unprognostic (2.72e-1)" "unprognostic (2.78e-1)" "potential prognostic favorable (2.64e-5)" "unprognostic (2.32e-2)" "unprognostic (1.38e-1)" "unprognostic (3.24e-1)" "unprognostic (4.45e-3)" "unprognostic (1.04e-1)" "unprognostic (1.22e-1)" "unprognostic (6.23e-2)" "unprognostic (7.02e-2)" "potential prognostic unfavorable (9.26e-4)" "unprognostic (4.08e-1)" "unprognostic (1.46e-1)" "unprognostic (2.54e-1)" "unprognostic (1.69e-2)" "unprognostic (2.63e-1)" "potential prognostic favorable (3.57e-4)" "unprognostic (2.84e-1)" "unprognostic (1.94e-2)" "unprognostic (1.42e-1)" "unprognostic (2.70e-1)" "unprognostic (3.52e-1)" EGR2 KROX20 ENSG00000122877 "Early growth response 2" P11161 10 62811996-62819167 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 56.3;thyroid gland: 114.5" "Cell type enhanced" "Detected in many" "Breast secretory cells: 115.5;Epididymal basal cells: 78.6;Epididymal principal cells: 453.6" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 453.6;Secretory cells: 115.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.7" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 36.0" "Group enriched" "Detected in all" 5 "cerebral cortex: 18.8;hippocampal formation: 11.4" "Group enriched" "Detected in some" 5 "intermediate monocyte: 2.3;non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 5 "monocytes: 2.3" "Cancer enhanced" "Detected in many" "lymphoma: 11.2" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031165, HPA065377" Approved Nucleoplasm NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 22: Epididymis - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 Nucleoplasm "HPA031165: , HPA065377: " "unprognostic (3.32e-1)" "potential prognostic favorable (7.46e-4)" "unprognostic (4.50e-2)" "unprognostic (6.62e-2)" "unprognostic (5.51e-2)" "unprognostic (1.30e-2)" "unprognostic (1.84e-1)" "unprognostic (8.89e-3)" "unprognostic (2.39e-1)" "unprognostic (2.81e-1)" "unprognostic (1.24e-1)" "unprognostic (9.22e-2)" "unprognostic (7.14e-2)" "unprognostic (2.23e-1)" "potential prognostic favorable (6.35e-4)" "unprognostic (1.70e-2)" "unprognostic (6.16e-2)" "unprognostic (2.85e-2)" "unprognostic (4.33e-1)" "unprognostic (1.41e-2)" "unprognostic (2.31e-1)" "unprognostic (7.25e-2)" "unprognostic (2.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (3.63e-3)" "unprognostic (1.47e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (1.04e-1)" "unprognostic (2.55e-2)" EHD1 "FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1" ENSG00000110047 "EH domain containing 1" Q9H4M9 11 64851642-64888296 "Plasma proteins, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 143.0;testis: 148.3" "Group enriched" "Detected in many" 5 "Early spermatids: 1211.5;Late spermatids: 3099.1;Neutrophils: 1042.5" "Group enriched" "Detected in many" 6 "Neutrophils: 1042.5;Spermatogenic cell types: 3099.1" "Cell type enhanced" "Detected in all" "leukocyte: 56.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA049890, HPA049986, HPA066751, HPA067747" Approved Supported "Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA 6100000 "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 46 "Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA049890: , HPA049986: , HPA066751: , HPA067747: " "unprognostic (2.37e-1)" "unprognostic (1.86e-1)" "unprognostic (2.83e-3)" "unprognostic (1.60e-2)" "unprognostic (1.21e-1)" "unprognostic (8.89e-2)" "unprognostic (2.12e-1)" "unprognostic (1.09e-2)" "unprognostic (3.00e-1)" "unprognostic (3.57e-3)" "potential prognostic favorable (2.48e-6)" "unprognostic (7.85e-2)" "unprognostic (4.58e-2)" "potential prognostic unfavorable (3.82e-8)" "unprognostic (3.20e-2)" "unprognostic (6.10e-2)" "potential prognostic unfavorable (9.09e-4)" "unprognostic (1.86e-3)" "unprognostic (2.79e-1)" "unprognostic (2.02e-2)" "unprognostic (4.69e-1)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (1.66e-1)" "unprognostic (1.20e-1)" "unprognostic (6.53e-2)" "unprognostic (8.27e-2)" "unprognostic (2.10e-2)" "unprognostic (2.64e-1)" "unprognostic (4.98e-2)" "unprognostic (5.34e-2)" "unprognostic (2.08e-1)" EHD2 PAST2 ENSG00000024422 "EH domain containing 2" Q9NZN4 19 47713422-47743134 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 246.8;Decidual stromal cells: 129.5;Fibroblasts: 70.6;Hepatic stellate cells: 135.6;Leydig cells: 94.2;Lymphatic endothelial cells: 99.3;Pericytes: 179.2;Peritubular myoid cells: 101.4;Vascular endothelial cells: 72.1;Vascular smooth muscle cells: 164.0" "Cell type enhanced" "Detected in many" "Alveolar cells: 246.8;Mural cells: 179.2;Stellate cells: 135.6;Stromal cells: 129.5" "Group enriched" "Detected in many" 5 "pericyte: 142.0;vascular associated smooth muscle cell: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Alveolar cell types: 303979787.1;Capillaries: 347039601.4;Smooth muscle cells: 490963849.0" "Low tissue specificity" "Detected in all" "HPA047394, HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA 740000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 110: Mural cells - ECM organization" 4 "Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA047394: , HPA049890: , HPA049986: , HPA066751: " "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" "unprognostic (7.23e-3)" "unprognostic (2.27e-2)" "unprognostic (5.12e-2)" "unprognostic (6.52e-2)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (2.01e-2)" "unprognostic (2.71e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (3.81e-2)" "unprognostic (8.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.49e-1)" "unprognostic (1.78e-2)" "unprognostic (3.16e-2)" "unprognostic (1.28e-2)" "unprognostic (3.80e-3)" "unprognostic (1.40e-3)" "unprognostic (2.05e-1)" "unprognostic (7.77e-3)" "unprognostic (1.06e-2)" "unprognostic (7.60e-2)" "unprognostic (1.73e-2)" "unprognostic (5.22e-2)" "unprognostic (4.28e-2)" "unprognostic (7.65e-3)" "unprognostic (7.03e-2)" "unprognostic (5.73e-2)" "unprognostic (1.30e-1)" EHD3 PAST3 ENSG00000013016 "EH domain containing 3" Q9NZN3 2 31234152-31269451 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 41.0;esophagus: 40.9" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 331.5;Esophageal suprabasal cells: 44.7;Megakaryocytes: 105.1;Ocular epithelial cells: 67.8;Oligodendrocyte progenitor cells: 58.5;Platelets: 273.4;Syncytiotrophoblasts: 88.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 331.5;Megakaryocytes: 105.1;Platelets: 273.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 20.9;naive B-cell: 5.6" "Lineage enriched" "Detected in many" 7 "B-cells: 20.9" "Low cancer specificity" "Detected in many" "Liver - Sinusoid Endothelial cells, Prostate - Fibroblasts, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 194862956.2" "Tissue enriched" "Detected in many" "cerebral cortex: 67716930.1" "HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA 8800000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 14 "Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA049890: , HPA049986: , HPA066751: " "unprognostic (1.77e-1)" "unprognostic (7.39e-2)" "unprognostic (2.23e-1)" "unprognostic (7.85e-2)" "unprognostic (2.18e-1)" "unprognostic (5.98e-2)" "unprognostic (1.83e-1)" "unprognostic (6.04e-3)" "unprognostic (1.58e-1)" "unprognostic (2.82e-2)" "validated prognostic favorable (5.01e-6)" "validated prognostic favorable (5.45e-4)" "unprognostic (2.35e-1)" "unprognostic (9.24e-2)" "unprognostic (2.37e-2)" "unprognostic (8.92e-2)" "unprognostic (1.57e-3)" "unprognostic (5.09e-2)" "unprognostic (1.74e-1)" "unprognostic (7.71e-3)" "unprognostic (3.85e-2)" "unprognostic (4.76e-2)" "unprognostic (3.02e-1)" "unprognostic (2.87e-1)" "unprognostic (4.43e-1)" "unprognostic (7.41e-2)" "unprognostic (2.51e-1)" "unprognostic (2.24e-3)" "unprognostic (1.63e-1)" "unprognostic (5.07e-3)" "unprognostic (2.26e-2)" EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 305.4;Urothelial cells: 435.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 435.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 50.4;endothelial cell: 61.1;oligodendrocyte precursor cell: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Uncertain "Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA 510000 "Cluster 33: Non-specific - ATP binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 "Plasma membrane" "Primary cilium, Primary cilium transition zone" "HPA049890: , HPA049986: , HPA052729: , HPA066751: " "unprognostic (3.79e-2)" "unprognostic (3.76e-2)" "unprognostic (1.81e-2)" "unprognostic (1.74e-2)" "unprognostic (6.29e-3)" "unprognostic (7.01e-3)" "unprognostic (4.76e-3)" "unprognostic (3.85e-3)" "unprognostic (2.21e-2)" "unprognostic (4.68e-2)" "potential prognostic favorable (3.95e-8)" "unprognostic (1.67e-3)" "unprognostic (2.49e-1)" "unprognostic (1.75e-1)" "unprognostic (2.37e-1)" "unprognostic (8.02e-2)" "potential prognostic unfavorable (1.83e-5)" "unprognostic (6.02e-3)" "unprognostic (2.50e-1)" "unprognostic (7.82e-2)" "unprognostic (7.30e-2)" "unprognostic (2.40e-2)" "unprognostic (8.09e-3)" "unprognostic (1.42e-1)" "unprognostic (2.18e-1)" "unprognostic (6.07e-2)" "unprognostic (6.95e-2)" "unprognostic (1.56e-1)" "unprognostic (3.10e-1)" "unprognostic (3.32e-1)" "unprognostic (2.79e-1)" EHF "ESE3, ESEJ" ENSG00000135373 "ETS homologous factor" Q9NZC4 11 34621093-34663288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 196.3;salivary gland: 270.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 972.0;Endometrial glandular cells: 877.5;Epididymal basal cells: 875.9;Esophageal apical cells: 3809.7;Esophageal suprabasal cells: 837.8;Lacrimal acinar cells: 2264.6;Ocular epithelial cells: 850.8;Prostatic club cells: 802.7;Prostatic hillock cells: 805.0;Salivary acinar cells: 1080.9" "Cell type enhanced" "Detected in many" "Acinar cells: 2264.6;Apical squamous epithelial cells: 3809.7" "Cell type enriched" "Detected in some" 5 "ependymal cell: 35.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "myeloid DC: 1.7" "Lineage enriched" "Detected in single" 11 "dendritic cells: 1.7" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Fallopian tube cells: 3492266.8;Large ducts: 2871937.6" "Group enriched" "Detected in some" "fallopian tube: 249629.4;intestine: 212341.7" "HPA050923, HPA060734" Enhanced Supported "Nucleoplasm,Golgi apparatus" No NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 Nucleoplasm "Golgi apparatus" "HPA050923: , HPA060734: " "unprognostic (5.53e-3)" "unprognostic (4.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.55e-1)" "unprognostic (8.00e-2)" "unprognostic (6.18e-2)" "unprognostic (4.75e-2)" "unprognostic (4.39e-3)" "unprognostic (9.48e-2)" "unprognostic (2.23e-3)" "unprognostic (3.42e-2)" "unprognostic (7.82e-2)" "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (3.36e-1)" "unprognostic (1.09e-1)" "unprognostic (8.10e-2)" "unprognostic (1.11e-1)" "unprognostic (9.91e-2)" "unprognostic (4.10e-3)" "unprognostic (7.29e-3)" "unprognostic (1.76e-2)" "unprognostic (2.52e-1)" "unprognostic (5.05e-3)" "unprognostic (4.91e-1)" "unprognostic (1.31e-1)" "unprognostic (1.34e-2)" "unprognostic (1.58e-1)" "unprognostic (2.35e-1)" "unprognostic (2.34e-1)" EHMT1 "bA188C12.1, EHMT1-IT1, Eu-HMTase1, FLJ12879, FLJ40292, GLP, KIAA1876, KMT1D" ENSG00000181090 "Euchromatic histone lysine methyltransferase 1" Q9H9B1 9 137618992-137870016 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 516.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1478507.1;Hepatocytes: 1332846.7" "Group enriched" "Detected in many" "bone marrow: 497897.0;intestine: 475630.1;lymphoid tissue: 828008.6;salivary gland: 451757.1" "HPA060022, HPA074729" Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 44: Plasma cells - Antibody production & secretion" 38 "Nucleoplasm, Nuclear bodies" "HPA060022: , HPA074729: " "unprognostic (1.22e-1)" "unprognostic (4.55e-2)" "unprognostic (3.98e-1)" "unprognostic (7.75e-2)" "unprognostic (1.09e-1)" "unprognostic (7.95e-2)" "unprognostic (1.78e-1)" "potential prognostic favorable (2.76e-4)" "unprognostic (3.06e-2)" "unprognostic (3.62e-2)" "unprognostic (1.32e-3)" "unprognostic (9.53e-3)" "unprognostic (1.09e-1)" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (2.94e-2)" "unprognostic (3.32e-3)" "unprognostic (1.05e-1)" "unprognostic (2.12e-1)" "unprognostic (2.03e-1)" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (3.81e-2)" "unprognostic (1.49e-2)" "unprognostic (1.32e-2)" "unprognostic (7.80e-3)" "unprognostic (4.00e-1)" "unprognostic (8.91e-3)" "unprognostic (3.22e-1)" EHMT2 "BAT8, C6orf30, Em:AF134726.3, G9A, KMT1C, NG36/G9a" ENSG00000204371 "Euchromatic histone lysine methyltransferase 2" Q96KQ7 6 31879759-31897698 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 32.9;Brain inhibitory neurons: 31.6;Late spermatids: 31.0;Oligodendrocyte progenitor cells: 30.0;Oligodendrocytes: 36.0" "Cell type enhanced" "Detected in many" "Glial cells: 36.0;Neuronal cells: 31.6;Spermatogenic cell types: 31.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 2099734.2;T-cells: 1985659.8" "Tissue enhanced" "Detected in some" "bone marrow: 3138976.9;lymphoid tissue: 3117349.4;salivary gland: 3515292.3" "HPA050550, HPA060259" Supported Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 96 "Nucleoplasm, Nuclear speckles" "HPA050550: , HPA060259: " "unprognostic (2.86e-1)" "unprognostic (1.16e-1)" "unprognostic (1.28e-1)" "unprognostic (5.58e-2)" "unprognostic (1.96e-1)" "unprognostic (1.14e-1)" "unprognostic (1.12e-2)" "unprognostic (2.96e-3)" "unprognostic (7.87e-2)" "unprognostic (2.52e-2)" "unprognostic (3.75e-3)" "unprognostic (1.97e-1)" "unprognostic (3.11e-1)" "unprognostic (8.03e-2)" "unprognostic (3.14e-1)" "unprognostic (1.64e-1)" "unprognostic (5.53e-3)" "unprognostic (2.23e-1)" "unprognostic (7.40e-2)" "unprognostic (4.87e-2)" "unprognostic (5.46e-2)" "unprognostic (3.52e-1)" "unprognostic (1.99e-1)" "unprognostic (5.29e-1)" "unprognostic (8.63e-2)" "unprognostic (2.69e-2)" "unprognostic (3.31e-1)" EID2 "CRI2, EID-2, MGC20452" ENSG00000176396 "EP300 interacting inhibitor of differentiation 2" Q8N6I1 19 39538707-39540161 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 57.7" "Cell type enhanced" "Detected in many" "Trophoblast cells: 57.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7713 "Fallopian tube cells: 771322.6" "Tissue enriched" "Detected in single" 26446 "cerebral cortex: 2644583.8" HPA045477 Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 24: Non-specific - Transcription" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 3 Nucleoplasm Centrosome "HPA045477: " "unprognostic (2.41e-1)" "unprognostic (4.76e-1)" "unprognostic (2.07e-1)" "unprognostic (6.97e-2)" "unprognostic (4.41e-3)" "unprognostic (3.66e-2)" "unprognostic (7.01e-2)" "unprognostic (2.60e-1)" "unprognostic (3.99e-2)" "unprognostic (6.82e-2)" "unprognostic (3.80e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "potential prognostic unfavorable (1.86e-5)" "unprognostic (7.93e-2)" "unprognostic (3.62e-2)" "unprognostic (8.08e-3)" "unprognostic (1.43e-2)" "unprognostic (5.37e-2)" "unprognostic (1.01e-1)" "unprognostic (5.08e-2)" "unprognostic (4.41e-2)" "unprognostic (2.76e-1)" "unprognostic (2.13e-3)" "unprognostic (3.15e-2)" "unprognostic (1.73e-1)" "unprognostic (2.96e-1)" "unprognostic (8.63e-2)" "unprognostic (6.51e-2)" "unprognostic (1.85e-1)" "unprognostic (1.24e-2)" EIF1AD "haponin, MGC11102" ENSG00000175376 "Eukaryotic translation initiation factor 1A domain containing" Q8N9N8 11 65996545-66002176 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 51.0;Megakaryocytes: 49.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 903178.8;Neurons: 325099.1" "Low tissue specificity" "Detected in many" "HPA054991, HPA058735" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 41 "Nucleoplasm, Vesicles" Cytosol "HPA054991: , HPA058735: " "unprognostic (7.70e-2)" "unprognostic (3.55e-2)" "unprognostic (1.04e-1)" "unprognostic (3.46e-2)" "unprognostic (6.81e-2)" "unprognostic (4.46e-2)" "unprognostic (4.46e-2)" "unprognostic (1.47e-1)" "unprognostic (1.60e-2)" "unprognostic (8.58e-3)" "unprognostic (4.52e-3)" "unprognostic (1.59e-2)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (5.13e-4)" "unprognostic (9.14e-2)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (2.85e-1)" "unprognostic (3.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (3.04e-3)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (3.52e-3)" "unprognostic (2.89e-2)" "unprognostic (1.02e-1)" "unprognostic (2.07e-1)" "unprognostic (6.80e-2)" "unprognostic (1.62e-1)" "unprognostic (3.56e-1)" "unprognostic (1.95e-2)" EIF2AK4 "GCN2, KIAA1338" ENSG00000128829 "Eukaryotic translation initiation factor 2 alpha kinase 4" Q9P2K8 15 39934115-40035591 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Activation of host autophagy by virus, Adaptive immunity, Antiviral defense, Cell cycle, Growth arrest, Host-virus interaction, Immunity, Neurogenesis, Stress response, Translation regulation" "Activator, Kinase, RNA-binding, Serine/threonine-protein kinase, Transferase, tRNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 345.9" "Cell type enhanced" "Detected in all" "Plasma cells: 345.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 66.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "cerebral cortex: 1213354.9" HPA011811 Approved Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 44: Plasma cells - Antibody production & secretion" 4 Cytosol "HPA011811: " "unprognostic (5.17e-2)" "unprognostic (9.61e-2)" "unprognostic (9.53e-2)" "unprognostic (4.15e-1)" "unprognostic (1.89e-1)" "unprognostic (6.26e-2)" "unprognostic (3.11e-1)" "unprognostic (5.08e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-1)" "unprognostic (2.65e-3)" "unprognostic (1.00e-1)" "unprognostic (2.84e-1)" "unprognostic (2.62e-1)" "unprognostic (8.76e-2)" "unprognostic (1.59e-2)" "unprognostic (1.35e-2)" "unprognostic (6.61e-3)" "unprognostic (6.70e-2)" "unprognostic (1.57e-1)" "unprognostic (2.13e-1)" "unprognostic (3.79e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (8.06e-2)" "unprognostic (4.08e-2)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (1.88e-1)" "unprognostic (8.15e-2)" "unprognostic (3.51e-2)" EIF2D LGTN ENSG00000143486 "Eukaryotic translation initiation factor 2D" P41214 1 206571292-206612465 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA028220 Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 3 Cytosol "Nuclear bodies" "HPA028220: " "unprognostic (2.49e-1)" "unprognostic (1.98e-1)" "unprognostic (9.02e-2)" "unprognostic (2.03e-1)" "unprognostic (2.50e-1)" "unprognostic (2.55e-1)" "unprognostic (3.11e-1)" "unprognostic (2.60e-1)" "unprognostic (6.72e-3)" "unprognostic (1.04e-3)" "unprognostic (2.49e-1)" "unprognostic (6.41e-3)" "unprognostic (1.01e-2)" "unprognostic (1.60e-2)" "unprognostic (5.48e-2)" "unprognostic (2.12e-1)" "unprognostic (4.88e-2)" "unprognostic (2.68e-1)" "unprognostic (4.05e-1)" "unprognostic (2.88e-2)" "unprognostic (3.80e-1)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.98e-1)" "unprognostic (8.33e-2)" "unprognostic (1.29e-1)" "unprognostic (2.38e-1)" "unprognostic (3.11e-1)" "unprognostic (3.23e-2)" "unprognostic (3.75e-3)" EIF3A "EIF3, eIF3-p170, eIF3-theta, EIF3S10, KIAA0139, TIF32" ENSG00000107581 "Eukaryotic translation initiation factor 3 subunit A" Q14152 10 119033670-119080823 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 754.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA038315, HPA038316" Enhanced Approved Nucleoplasm,Cytosol Yes No 140000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 140 "Nucleoplasm, Cytosol" "HPA038315: , HPA038316: " "unprognostic (2.21e-2)" "unprognostic (1.89e-1)" "unprognostic (3.37e-1)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (1.93e-1)" "unprognostic (7.10e-2)" "unprognostic (1.63e-3)" "unprognostic (1.37e-2)" "unprognostic (4.35e-1)" "unprognostic (5.18e-3)" "potential prognostic favorable (5.51e-7)" "unprognostic (1.08e-2)" "unprognostic (4.31e-2)" "unprognostic (2.93e-2)" "unprognostic (3.33e-2)" "unprognostic (7.84e-2)" "unprognostic (2.42e-3)" "unprognostic (4.09e-2)" "unprognostic (2.99e-1)" "unprognostic (7.64e-2)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (2.86e-2)" "unprognostic (7.53e-2)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (2.62e-1)" "unprognostic (1.74e-1)" "unprognostic (2.33e-1)" "unprognostic (4.23e-2)" "unprognostic (4.79e-2)" EIF3I "eIF3-beta, eIF3-p36, EIF3S2, TRIP-1" ENSG00000084623 "Eukaryotic translation initiation factor 3 subunit I" Q13347 1 32221077-32245397 "Essential proteins, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 469.2;Esophageal suprabasal cells: 522.4;Extravillous trophoblasts: 401.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA029939, HPA029940" Enhanced Approved Cytosol NA NA 26000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 101 Cytosol "HPA029939: , HPA029940: " "unprognostic (6.70e-2)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (1.13e-1)" "unprognostic (1.30e-2)" "unprognostic (5.18e-2)" "unprognostic (2.33e-1)" "unprognostic (2.19e-1)" "unprognostic (5.33e-3)" "unprognostic (2.98e-3)" "unprognostic (1.57e-2)" "unprognostic (2.51e-1)" "unprognostic (2.76e-1)" "unprognostic (1.31e-3)" "unprognostic (7.28e-3)" "unprognostic (9.31e-3)" "potential prognostic unfavorable (1.48e-5)" "unprognostic (2.97e-1)" "unprognostic (7.30e-2)" "unprognostic (2.98e-1)" "unprognostic (7.46e-2)" "unprognostic (9.86e-3)" "unprognostic (8.79e-2)" "unprognostic (2.23e-1)" "unprognostic (1.35e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-2)" "unprognostic (3.38e-1)" "unprognostic (5.13e-3)" "unprognostic (2.06e-3)" "unprognostic (9.10e-3)" EIF3K "ARG134, EIF3S12, HSPC029, M9, PLAC-24, PRO1474, PTD001" ENSG00000178982 "Eukaryotic translation initiation factor 3 subunit K" Q9UBQ5 19 38619082-38636955 "Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 1055.1;Esophageal suprabasal cells: 1086.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA045446, HPA054590" Uncertain Supported Cytosol No No 8800 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 105 Cytosol "HPA045446: , HPA054590: " "unprognostic (2.75e-1)" "unprognostic (3.86e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (2.46e-5)" "unprognostic (2.32e-1)" "unprognostic (1.75e-1)" "unprognostic (2.50e-1)" "unprognostic (2.05e-3)" "unprognostic (1.57e-1)" "unprognostic (4.74e-1)" "potential prognostic favorable (2.98e-5)" "unprognostic (3.05e-1)" "unprognostic (7.31e-3)" "unprognostic (1.62e-3)" "unprognostic (2.38e-3)" "unprognostic (2.09e-2)" "unprognostic (1.87e-1)" "unprognostic (3.68e-2)" "unprognostic (2.67e-2)" "unprognostic (1.89e-3)" "unprognostic (1.32e-1)" "unprognostic (2.61e-2)" "unprognostic (1.19e-1)" "unprognostic (1.09e-2)" "unprognostic (4.59e-2)" "unprognostic (1.31e-1)" "unprognostic (7.82e-2)" "unprognostic (3.48e-2)" "unprognostic (2.34e-1)" "unprognostic (2.72e-1)" "unprognostic (1.89e-1)" EIF3M "FLJ29030, GA17, hfl-B5, PCID1, TANGO7" ENSG00000149100 "Eukaryotic translation initiation factor 3 subunit M" Q7L2H7 11 32583798-32606264 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Initiation factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 520.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA031063 Approved Approved Cytosol NA NA 210000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 104 Cytosol "HPA031063: " "potential prognostic unfavorable (2.19e-4)" "unprognostic (3.74e-2)" "unprognostic (2.41e-2)" "unprognostic (2.52e-1)" "unprognostic (2.16e-1)" "unprognostic (5.06e-2)" "unprognostic (1.86e-2)" "unprognostic (1.85e-1)" "unprognostic (2.48e-3)" "potential prognostic unfavorable (3.57e-4)" "potential prognostic favorable (9.59e-6)" "unprognostic (3.19e-1)" "unprognostic (7.77e-3)" "validated prognostic unfavorable (7.29e-8)" "validated prognostic unfavorable (3.76e-4)" "validated prognostic unfavorable (1.04e-7)" "validated prognostic unfavorable (7.94e-5)" "unprognostic (2.32e-2)" "unprognostic (1.32e-1)" "unprognostic (4.35e-2)" "unprognostic (3.38e-3)" "potential prognostic unfavorable (3.13e-5)" "unprognostic (3.15e-2)" "unprognostic (8.62e-2)" "unprognostic (1.41e-2)" "unprognostic (7.31e-2)" "unprognostic (9.52e-3)" "unprognostic (5.13e-2)" "unprognostic (1.91e-1)" "unprognostic (3.82e-2)" "unprognostic (2.57e-2)" EIF4A3 "DDX48, EIF4AIII, Fal1, KIAA0111" ENSG00000141543 "Eukaryotic translation initiation factor 4A3" P38919 17 80134369-80147151 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, rRNA processing, Translation regulation, Transport" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "pDCs: 420.9;Urothelial cells: 406.2" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 91.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA021878 Supported Supported Nucleoplasm,Vesicles,Cytosol NA NA 400000 "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 103: Non-specific - Basic cellular processes" 159 Nucleoplasm "Vesicles, Cytosol" "HPA021878: " "unprognostic (1.55e-2)" "unprognostic (1.84e-2)" "unprognostic (1.14e-1)" "unprognostic (6.67e-2)" "unprognostic (1.28e-2)" "unprognostic (1.59e-1)" "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (2.88e-3)" "unprognostic (6.59e-2)" "potential prognostic favorable (3.15e-4)" "unprognostic (1.02e-2)" "unprognostic (5.39e-3)" "validated prognostic unfavorable (2.57e-4)" "validated prognostic unfavorable (3.42e-7)" "unprognostic (3.08e-3)" "potential prognostic unfavorable (1.41e-5)" "unprognostic (1.74e-1)" "unprognostic (3.00e-2)" "unprognostic (4.12e-1)" "unprognostic (3.36e-2)" "unprognostic (4.64e-2)" "unprognostic (1.24e-1)" "unprognostic (1.96e-2)" "unprognostic (6.52e-2)" "unprognostic (2.26e-1)" "unprognostic (2.01e-1)" "unprognostic (2.98e-2)" "unprognostic (3.78e-1)" "unprognostic (3.82e-1)" "unprognostic (3.25e-1)" EIF4EBP1 "4E-BP1, PHAS-I" ENSG00000187840 "Eukaryotic translation initiation factor 4E binding protein 1" Q13541 8 38030534-38060365 "Cancer-related genes, Predicted intracellular proteins" "Translation regulation" "Protein synthesis inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 309.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 249.4;Esophageal apical cells: 504.0;Esophageal basal cells: 492.6;Esophageal suprabasal cells: 550.3;Extravillous trophoblasts: 290.7;Gastric progenitor cells: 269.2;Hofbauer cells: 299.0;Pancreatic acinar cells: 435.8;Salivary acinar cells: 282.6" "Cell type enhanced" "Detected in many" "Acinar cells: 435.8;Apical squamous epithelial cells: 504.0;Basal cells: 492.6;Suprabasal cells: 550.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Macrophages: 176699.6;Oocytes: 581576.6" "Tissue enhanced" "Detected in many" "salivary gland: 16902571.6" "CAB005032, CAB005039, HPA023501" Supported Supported Nucleoplasm,Cytosol NA NA 33000 "Cluster 29: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 39: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 85: Squamous epithelial cells - Keratinization" 28 "Nucleoplasm, Cytosol" "CAB005032: , CAB005039: , HPA023501: " "unprognostic (1.07e-1)" "unprognostic (2.00e-3)" "unprognostic (6.45e-3)" "unprognostic (8.02e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (6.26e-5)" "unprognostic (5.01e-2)" "unprognostic (1.51e-1)" "unprognostic (2.88e-1)" "potential prognostic unfavorable (3.09e-5)" "potential prognostic unfavorable (6.97e-8)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (3.28e-8)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (2.92e-2)" "unprognostic (4.68e-3)" "unprognostic (2.29e-3)" "unprognostic (1.98e-2)" "unprognostic (4.17e-1)" "unprognostic (2.69e-2)" "unprognostic (2.85e-1)" "unprognostic (1.55e-3)" "unprognostic (2.25e-1)" "unprognostic (3.24e-1)" "unprognostic (3.01e-1)" "unprognostic (4.18e-2)" "unprognostic (2.95e-1)" "unprognostic (1.69e-1)" "unprognostic (2.38e-1)" "unprognostic (1.57e-2)" "unprognostic (9.31e-3)" EIF5 ENSG00000100664 "Eukaryotic translation initiation factor 5" P55010 14 103333544-103345025 "Essential proteins, Predicted intracellular proteins" "Protein biosynthesis" "GTPase activation, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1162.6" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1162.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA000867, CAB004226" Supported Approved "Plasma membrane,Primary cilium,Primary cilium tip,Cytosol" NA NA 93000 "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 20: Non-specific - Transcription regulation" 96 Cytosol "Plasma membrane, Primary cilium, Primary cilium tip" "CAB004226: , HPA000867: " "unprognostic (1.37e-1)" "unprognostic (3.59e-2)" "unprognostic (3.96e-2)" "unprognostic (2.70e-2)" "unprognostic (1.22e-1)" "unprognostic (1.72e-1)" "unprognostic (2.06e-1)" "unprognostic (7.30e-2)" "unprognostic (2.80e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (5.69e-7)" "unprognostic (1.68e-2)" "potential prognostic favorable (6.55e-4)" "unprognostic (3.68e-2)" "unprognostic (8.51e-2)" "unprognostic (1.66e-1)" "unprognostic (3.19e-2)" "unprognostic (1.76e-2)" "unprognostic (1.47e-2)" "unprognostic (2.31e-1)" "unprognostic (4.35e-3)" "unprognostic (2.13e-2)" "unprognostic (8.28e-2)" "unprognostic (2.16e-3)" "unprognostic (3.64e-2)" "unprognostic (1.09e-1)" "unprognostic (6.16e-2)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-2)" "unprognostic (2.13e-1)" ELAVL1 "Hua, HUR, MelG" ENSG00000066044 "ELAV like RNA binding protein 1" Q15717 19 7958573-8005659 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 250.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB005256, HPA046298" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 15000 "Cluster 45: Eosinophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 197 Nucleoplasm "Nucleoli, Cytosol" "CAB005256: , HPA046298: " "unprognostic (4.69e-1)" "unprognostic (1.38e-1)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" "unprognostic (3.45e-2)" "unprognostic (1.57e-1)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-2)" "unprognostic (1.39e-1)" "potential prognostic favorable (7.44e-6)" "unprognostic (1.69e-1)" "unprognostic (2.08e-1)" "unprognostic (8.62e-3)" "unprognostic (3.91e-3)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (5.24e-1)" "unprognostic (1.91e-2)" "unprognostic (2.39e-2)" "unprognostic (1.17e-1)" "unprognostic (7.83e-3)" "unprognostic (5.96e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (3.59e-2)" "unprognostic (6.56e-2)" "unprognostic (2.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.52e-1)" "unprognostic (1.75e-1)" ELF3 "EPR-1, ERT, ESE-1, ESX" ENSG00000163435 "E74 like ETS transcription factor 3" P78545 1 202007945-202017183 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Inflammatory response, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 229.3" "Cell type enhanced" "Detected in many" "Colonocytes: 1283.5;Endometrial glandular cells: 1004.6;Esophageal apical cells: 4004.9;Foveolar cells: 957.8;Goblet cells: 1187.3;Prostatic club cells: 1509.8;Prostatic hillock cells: 1267.1;Urothelial cells: 1275.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 4004.9;Glandular cells: 1509.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Cell type enriched" "Detected in single" 2073 "Large ducts: 207324.5" "Not detected" "Not detected" "HPA003316, HPA003479" Enhanced Enhanced Nucleoplasm NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 12 Nucleoplasm "HPA003316: , HPA003479: " "unprognostic (1.89e-3)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (1.90e-1)" "unprognostic (1.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (4.98e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-2)" "unprognostic (1.39e-2)" "unprognostic (6.23e-2)" "unprognostic (4.38e-1)" "unprognostic (2.20e-2)" "unprognostic (7.98e-2)" "unprognostic (4.00e-2)" "unprognostic (2.35e-3)" "unprognostic (4.20e-2)" "unprognostic (9.25e-3)" "unprognostic (2.97e-1)" "unprognostic (5.25e-2)" "unprognostic (9.50e-2)" "unprognostic (1.56e-1)" "unprognostic (1.54e-1)" "unprognostic (1.78e-2)" "unprognostic (7.74e-2)" "unprognostic (4.10e-1)" "unprognostic (5.54e-2)" ELK1 ENSG00000126767 "ETS transcription factor ELK1" P19419 X 47635521-47650604 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 145.2" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 145.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 35039 "Granulosa cells: 5326532.8;Oocytes: 1681315.0" "Tissue enriched" "Detected in some" "ovary: 819967.4" "CAB003808, HPA036084, HPA064381" Enhanced Enhanced Nucleoplasm NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 94: Gonadal somatic cells - Mixed function" 22 Nucleoplasm "CAB003808: , HPA036084: , HPA064381: " "unprognostic (4.84e-2)" "unprognostic (7.00e-2)" "unprognostic (3.35e-1)" "unprognostic (6.56e-2)" "unprognostic (1.68e-1)" "unprognostic (1.47e-1)" "unprognostic (9.54e-2)" "unprognostic (1.96e-1)" "unprognostic (2.90e-1)" "unprognostic (3.12e-2)" "unprognostic (5.89e-3)" "unprognostic (1.54e-1)" "unprognostic (1.18e-2)" "unprognostic (2.06e-2)" "unprognostic (1.00e-3)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (7.49e-4)" "unprognostic (1.89e-1)" "unprognostic (2.63e-1)" "unprognostic (1.50e-1)" "unprognostic (4.15e-1)" "unprognostic (1.01e-1)" "unprognostic (2.50e-1)" "unprognostic (7.74e-2)" "unprognostic (5.34e-2)" "unprognostic (2.03e-3)" "unprognostic (1.31e-1)" "unprognostic (2.29e-1)" "unprognostic (8.74e-2)" "unprognostic (7.18e-2)" "unprognostic (2.66e-1)" ELL2 MRCCAT1 ENSG00000118985 "Elongation factor for RNA polymerase II 2" O00472 5 95885098-95961851 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mast cells: 2267.5;monocytes: 1491.8;Myosatellite cells: 1257.0;Neutrophils: 5147.6;Pancreatic acinar cells: 1448.3;Plasma cells: 1499.4;Salivary acinar cells: 1375.7" "Cell type enhanced" "Detected in all" "Mast cells: 2267.5;Neutrophils: 5147.6" "Cell type enhanced" "Detected in all" "oligodendrocyte: 567.6;vascular associated smooth muscle cell: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 7.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1886 "Neurons: 188605.1" "Not detected" "Not detected" HPA013569 Supported Nucleoplasm No No "Cluster 22: Eosinophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 28 Nucleoplasm "HPA013569: " "unprognostic (1.78e-1)" "unprognostic (1.91e-1)" "unprognostic (6.54e-2)" "unprognostic (1.28e-1)" "unprognostic (2.26e-2)" "unprognostic (1.03e-1)" "unprognostic (4.23e-1)" "unprognostic (7.52e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (2.58e-1)" "unprognostic (7.10e-2)" "unprognostic (3.86e-1)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.35e-1)" "unprognostic (3.16e-2)" "unprognostic (5.10e-2)" "unprognostic (4.30e-2)" "unprognostic (1.49e-1)" "unprognostic (7.03e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (3.21e-6)" "unprognostic (1.83e-1)" "unprognostic (3.84e-1)" "unprognostic (2.28e-1)" "unprognostic (6.19e-2)" "unprognostic (3.15e-3)" "unprognostic (4.77e-2)" "potential prognostic unfavorable (5.54e-4)" "unprognostic (8.66e-2)" ELL3 FLJ22637 ENSG00000128886 "Elongation factor for RNA polymerase II 3" Q9HB65 15 43772605-43777315 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 54.0;skin 1: 25.0" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 6.9;Colonocytes: 1.3;Enteric stem cells: 1.0;Enteric transient amplifying cells: 1.8;Enterocytes: 2.7;Ependymal cells: 1.2;Goblet cells: 1.2;Parietal cells: 1.8" "Cell type enhanced" "Detected in some" "Ciliated cells: 6.9;Enterocytes: 2.7;Gastric glandular cells: 1.8;Proliferating cells: 1.8" "Cell type enriched" "Detected in some" 7 "choroid plexus epithelial cell: 10.8" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 8 "choroid plexus: 11.0" "Group enriched" "Detected in some" 4 "memory B-cell: 11.2;naive B-cell: 17.0" "Lineage enriched" "Detected in many" 5 "B-cells: 17.0" "Cancer enriched" "Detected in many" 5 "lymphoma: 72.9" "Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Region enriched" "Detected in single" 11 "olfactory bulb: 1.9" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Granulosa cells: 7590.1;Neurons: 7189.2;T-cells: 23187.1" "Tissue enriched" "Detected in all" "intestine: 818747.5" "HPA028938, HPA073494" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 11 "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA028938: , HPA073494: " "unprognostic (9.95e-2)" "unprognostic (1.78e-2)" "unprognostic (3.92e-1)" "unprognostic (5.64e-2)" "unprognostic (1.34e-2)" "unprognostic (1.53e-2)" "unprognostic (3.34e-2)" "unprognostic (9.38e-2)" "unprognostic (2.52e-2)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (4.29e-2)" "unprognostic (2.39e-1)" "unprognostic (7.39e-2)" "unprognostic (2.16e-1)" "unprognostic (3.18e-1)" "unprognostic (2.54e-1)" "unprognostic (5.36e-2)" "unprognostic (3.29e-1)" "unprognostic (5.70e-2)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" ELOA2 "HsT832, TCEB3B, TCEB3L" ENSG00000206181 "Elongin A2" Q8IYF1 18 47032527-47035621 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 3.8" "Group enriched" "Detected in some" 4 "Early spermatids: 33.7;Late primary spermatocytes: 21.7" "Cell type enriched" "Detected in some" 8 "Spermatogenic cell types: 33.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041009, HPA043501, HPA048971, HPA049178, HPA050086, HPA053158" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 11 Nucleoplasm "Nucleoli, Cytosol" "HPA041009: , HPA043501: , HPA048971: , HPA049178: , HPA050086: , HPA053158: " ELOVL5 "dJ483K16.1, HELO1, SCA38" ENSG00000012660 "ELOVL fatty acid elongase 5" Q9NYP7 6 53267398-53349179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Transferase "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 707.4;Breast hormone-responsive cells: 563.4;Neutrophils: 1048.2;Prostatic glandular cells: 660.9" "Cell type enhanced" "Detected in all" "Neutrophils: 1048.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Skin - Sebaceous gland cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB017042, HPA047752, HPA054197" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 25 "Endoplasmic reticulum" "CAB017042: , HPA047752: , HPA054197: " "unprognostic (1.15e-1)" "unprognostic (9.36e-2)" "unprognostic (2.91e-1)" "unprognostic (1.77e-2)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (3.48e-1)" "unprognostic (2.24e-3)" "unprognostic (3.52e-2)" "unprognostic (3.38e-3)" "unprognostic (6.39e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (1.04e-8)" "unprognostic (1.08e-1)" "unprognostic (1.36e-3)" "unprognostic (2.29e-1)" "unprognostic (2.04e-3)" "unprognostic (1.23e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (8.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.95e-2)" "unprognostic (5.23e-2)" "unprognostic (3.68e-2)" "unprognostic (3.89e-3)" "unprognostic (9.93e-2)" "unprognostic (1.11e-1)" "unprognostic (1.11e-1)" "unprognostic (7.19e-3)" "unprognostic (1.35e-1)" EMG1 "C2F, Grcc2f, NEP1" ENSG00000126749 "EMG1 N1-specific pseudouridine methyltransferase" Q92979 12 6970913-6979936 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, rRNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 54.8;Extravillous trophoblasts: 68.2;Migrating cytotrophoblasts: 73.0" "Cell type enhanced" "Detected in many" "Trophoblast cells: 73.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 5829745.7;T-cells: 6518523.5" "Group enriched" "Detected in many" "intestine: 1668661.6;lymphoid tissue: 1658917.7" "HPA039304, HPA039666" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 22 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA039304: , HPA039666: " "unprognostic (3.38e-3)" "unprognostic (2.47e-1)" "potential prognostic favorable (6.45e-4)" "unprognostic (7.50e-2)" "unprognostic (1.14e-1)" "unprognostic (2.68e-1)" "unprognostic (2.15e-1)" "unprognostic (1.34e-1)" "unprognostic (9.72e-3)" "unprognostic (2.73e-2)" "unprognostic (5.12e-2)" "unprognostic (1.07e-1)" "unprognostic (5.52e-2)" "validated prognostic unfavorable (2.15e-4)" "validated prognostic unfavorable (3.18e-5)" "unprognostic (1.26e-2)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (2.30e-1)" "unprognostic (6.72e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (7.97e-3)" "unprognostic (3.38e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (6.19e-4)" "unprognostic (1.69e-1)" "unprognostic (1.13e-1)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (1.41e-1)" EML4 "C2orf2, ELP120, ROPP120" ENSG00000143924 "EMAP like 4" Q9HC35 2 42169353-42332548 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 1052.7;Neutrophil progenitors: 731.7;Neutrophils: 800.0;Pituicytes/FSCs: 672.7;T-cells: 898.7;Urothelial cells: 685.3" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 1052.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 543.8;leukocyte: 709.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Rhabdoid: 174.7" "Skeletal muscle - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 143255719.8" "Low tissue specificity" "Detected in all" "HPA036687, HPA036688, HPA065337" Enhanced Supported "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol,Perinuclear theca,Calyx,Principal piece,Annulus" Yes NA 25000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 29 "Microtubules, Primary cilium, Annulus" "Cytokinetic bridge, Cytosol, Perinuclear theca, Calyx, Principal piece" "HPA036687: , HPA036688: , HPA065337: " "unprognostic (1.51e-1)" "unprognostic (1.19e-1)" "unprognostic (7.71e-3)" "unprognostic (3.55e-2)" "unprognostic (2.15e-2)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (1.67e-2)" "unprognostic (4.26e-2)" "unprognostic (2.13e-3)" "potential prognostic favorable (1.20e-7)" "unprognostic (3.22e-2)" "unprognostic (4.54e-2)" "unprognostic (5.48e-2)" "unprognostic (9.11e-3)" "unprognostic (1.26e-1)" "unprognostic (2.47e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-1)" "unprognostic (8.68e-3)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (8.70e-4)" "unprognostic (2.68e-2)" "unprognostic (1.40e-1)" "unprognostic (7.47e-3)" "unprognostic (7.95e-2)" "unprognostic (1.09e-2)" "unprognostic (3.25e-1)" "unprognostic (2.81e-1)" "unprognostic (2.30e-2)" "unprognostic (9.38e-2)" EMP1 "CL-20, TMP" ENSG00000134531 "Epithelial membrane protein 1" P54849 12 13196723-13219941 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1936.4;vagina: 705.5" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 30858.3" "Cell type enriched" "Detected in many" 7 "Apical squamous epithelial cells: 30858.3" "Cell type enhanced" "Detected in many" "endothelial cell: 133.1;fibroblast: 80.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "myeloid DC: 3.5" "Lineage enriched" "Detected in single" 13 "dendritic cells: 3.5" "Cancer enhanced" "Detected in all" "Rhabdoid: 589.7" "Kidney - Endothelial cells, Spleen - Fibroblasts_2, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 5.9;spinal cord: 21.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA046912 Approved Vesicles NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 55 Vesicles "HPA046912: " "unprognostic (1.54e-1)" "unprognostic (1.58e-2)" "unprognostic (2.79e-1)" "unprognostic (2.70e-1)" "unprognostic (2.16e-1)" "unprognostic (2.07e-1)" "unprognostic (2.42e-1)" "unprognostic (2.15e-3)" "unprognostic (2.18e-1)" "unprognostic (2.67e-1)" "unprognostic (1.23e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (2.03e-1)" "unprognostic (1.07e-2)" "unprognostic (1.25e-2)" "unprognostic (4.06e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (1.30e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.13e-5)" "unprognostic (9.60e-2)" "potential prognostic unfavorable (9.74e-5)" "unprognostic (3.46e-3)" "unprognostic (3.85e-1)" "unprognostic (9.94e-2)" "potential prognostic favorable (5.28e-4)" "unprognostic (3.97e-2)" "unprognostic (3.23e-2)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (3.25e-2)" EMP2 XMP ENSG00000213853 "Epithelial membrane protein 2" P54851 16 10528422-10580632 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 214.6" "Cell type enriched" "Detected in many" 4 "Alveolar cells type 1: 5548.1" "Cell type enriched" "Detected in many" 4 "Alveolar cells: 5548.1" "Cell type enhanced" "Detected in many" "endothelial cell: 251.9;pericyte: 119.1;vascular associated smooth muscle cell: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 182 "lung: 18226.6" "HPA014711, HPA070816" Approved Approved Nucleoplasm,Cytosol No Yes "Cluster 58: Skin - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 81: Alveolar cells - Lung function" 1 Nucleoplasm Cytosol "HPA014711: , HPA070816: " "unprognostic (2.47e-2)" "unprognostic (3.55e-2)" "unprognostic (2.03e-1)" "unprognostic (3.35e-2)" "unprognostic (4.36e-2)" "unprognostic (8.06e-2)" "validated prognostic unfavorable (1.27e-4)" "validated prognostic unfavorable (3.33e-4)" "unprognostic (1.90e-1)" "unprognostic (4.55e-2)" "unprognostic (1.72e-1)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (6.54e-4)" "unprognostic (6.44e-3)" "unprognostic (8.42e-3)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (5.66e-2)" "unprognostic (2.48e-1)" "unprognostic (7.60e-2)" "unprognostic (1.99e-1)" "unprognostic (4.05e-2)" "unprognostic (2.80e-1)" "unprognostic (2.17e-1)" "unprognostic (1.67e-1)" "unprognostic (6.10e-2)" "unprognostic (3.57e-1)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (1.03e-1)" EMX1 ENSG00000135638 "Empty spiracles homeobox 1" Q04741 2 72916260-72936071 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 16.4;kidney: 39.9" "Group enriched" "Detected in some" 4 "Distal convoluted tubule cells: 236.7;Oocytes: 119.7;Renal collecting duct principal cells: 103.8;Renal connecting tubule cells: 257.1" "Group enriched" "Detected in some" 7 "Ductal cells: 257.1;Oocytes: 119.7;Renal nephron cells: 236.7" "Cell type enhanced" "Detected in some" "hippocampal CA4: 22.0;upper-layer intratelencephalic: 22.6" "Group enriched" "Detected in many" 6 "Kidney Chromophobe (TCGA): 23.6;Kidney Renal Clear Cell Carcinoma (TCGA): 8.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 20.1" "Group enriched" "Detected in many" 10 "amygdala: 15.8;basal ganglia: 21.8;cerebral cortex: 58.5;hippocampal formation: 21.1;white matter: 31.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Kidney - Intercalated cells" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 14 "amygdala: 4.5;cerebral cortex: 14.5;hippocampal formation: 11.1" "Group enriched" "Detected in some" "Collecting ducts: 15851712.0;Proximal tubules: 26301382.1" "Not detected" "Not detected" "HPA006230, HPA006421" Approved Supported "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA006230: , HPA006421: " "unprognostic (8.02e-2)" "unprognostic (1.66e-2)" "unprognostic (6.24e-2)" "unprognostic (1.80e-1)" "unprognostic (1.52e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.65e-4)" "unprognostic (3.04e-2)" "unprognostic (4.56e-3)" "unprognostic (2.80e-1)" "unprognostic (5.80e-2)" "unprognostic (7.08e-2)" "unprognostic (2.31e-1)" EN1 ENSG00000163064 "Engrailed homeobox 1" Q05925 2 118842171-118847648 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" Dwarfism "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adipose tissue: 3.4;brain: 8.5;skeletal muscle: 13.0;skin 1: 10.0" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 3.0;Breast myoepithelial cells: 4.3;Breast secretory cells: 10.2;Epididymal clear cells: 6.1;Fibroblasts: 3.2;Myonuclei: 9.6;Myosatellite cells: 8.1;Other brain neurons: 3.1;Pericytes: 2.7;Smooth muscle cells: 36.4" "Cell type enhanced" "Detected in some" "Myocytes: 9.6;Secretory cells: 10.2;Smooth muscle cells: 36.4;Stem cells: 8.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.0;oligodendrocyte precursor cell: 3.5" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 9.2" "Region enriched" "Detected in many" 6 "midbrain: 42.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 6.7;breast cancer: 6.9" "Skin - Eccrine sweat gland cells" "Region enriched" "Detected in single" 5 "midbrain: 4.9" "Region enriched" "Detected in some" 6 "midbrain: 28.7" "Not detected" "Not detected" "Not detected" "Not detected" "CAB014884, HPA073141" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Nucleoli rim" Nucleoplasm "CAB014884: , HPA073141: " "unprognostic (3.46e-2)" "unprognostic (8.58e-2)" "unprognostic (1.03e-1)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (1.65e-2)" "unprognostic (3.02e-1)" "unprognostic (2.87e-1)" "unprognostic (2.86e-1)" "unprognostic (9.61e-2)" "unprognostic (8.85e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (2.99e-4)" EN2 ENSG00000164778 "Engrailed homeobox 2" P19622 7 155458129-155464831 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "brain: 34.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 6.8;Brain excitatory neurons: 12.2;Endometrial glandular cells: 10.3;Endometrial luminal cells: 7.4;Epididymal efferent duct absorptive cells: 23.7;Epididymal efferent duct ciliated cells: 10.1;Melanocytes: 5.6;Oocytes: 4.6" "Cell type enhanced" "Detected in some" "Ciliated cells: 10.1;Ductal cells: 23.7;Glandular cells: 10.3;Luminal cells: 7.4;Neuronal cells: 12.2" "Group enriched" "Detected in some" 4 "cerebellar inhibitory: 41.5;upper rhombic lip: 38.7" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 10.1" "Group enriched" "Detected in many" 6 "cerebellum: 38.7;midbrain: 16.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 12.7" "Testis - Spermatocytes" "Region enriched" "Detected in some" 8 "cerebellum: 27.8" "Region enriched" "Detected in many" 5 "cerebellum: 82.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045646, HPA069809" Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" No No "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "Nucleoli, Nucleoli fibrillar center" "HPA045646: , HPA069809: " "unprognostic (3.55e-2)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (1.05e-2)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (5.95e-3)" "unprognostic (2.13e-1)" "unprognostic (4.44e-2)" ENGASE FLJ21865 ENSG00000167280 Endo-beta-N-acetylglucosaminidase Q8NFI3 17 79074824-79088599 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 68.4" "Cell type enhanced" "Detected in many" "Myocytes: 68.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 4424416.1" "Low tissue specificity" "Detected in many" HPA021551 Approved Approved Centrosome,Cytosol No No "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Myocytes - Oxidative muscle function" Cytosol Centrosome "HPA021551: " "unprognostic (9.83e-2)" "unprognostic (1.24e-1)" "unprognostic (9.53e-3)" "unprognostic (4.43e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-2)" "unprognostic (1.97e-1)" "unprognostic (1.75e-1)" "unprognostic (6.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-3)" "unprognostic (2.50e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-3)" "unprognostic (7.31e-2)" "unprognostic (9.48e-3)" "unprognostic (4.84e-1)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (4.65e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (2.94e-5)" "unprognostic (1.16e-3)" "unprognostic (9.91e-2)" "potential prognostic favorable (6.34e-5)" "unprognostic (1.70e-2)" "unprognostic (3.10e-2)" "unprognostic (2.64e-3)" "unprognostic (4.92e-1)" "unprognostic (3.81e-2)" "unprognostic (1.86e-1)" ENKD1 "C16orf48, DKFZP434A1319, FBB11" ENSG00000124074 "Enkurin domain containing 1" Q9H0I2 16 67662945-67667265 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 40.4;Endometrial ciliated cells: 42.7;Epididymal efferent duct ciliated cells: 49.9;Fallopian tube ciliated cells: 74.7;Respiratory ciliated cells: 81.7" "Cell type enhanced" "Detected in all" "Ciliated cells: 81.7" "Cell type enhanced" "Detected in all" "ependymal cell: 35.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 48351 "Fallopian tube cells: 4835077.5" "Group enriched" "Detected in some" 51383 "fallopian tube: 2107186.8;intestine: 8169400.0" "HPA041163, HPA041478" Approved Supported "Plasma membrane,Primary cilium,Centrosome,Basal body" NA No "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 2: Neurons - Nucleosome" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 171 "Plasma membrane, Centrosome, Basal body" "Primary cilium" "HPA041163: , HPA041478: " "unprognostic (7.44e-2)" "unprognostic (7.09e-2)" "unprognostic (7.24e-2)" "unprognostic (1.54e-3)" "unprognostic (2.53e-2)" "unprognostic (1.70e-1)" "unprognostic (1.36e-2)" "unprognostic (1.57e-1)" "unprognostic (1.86e-1)" "unprognostic (6.59e-2)" "unprognostic (4.55e-2)" "potential prognostic favorable (3.48e-5)" "unprognostic (5.67e-3)" "unprognostic (1.32e-1)" "unprognostic (1.25e-1)" "unprognostic (1.29e-2)" "unprognostic (2.53e-1)" "unprognostic (6.56e-2)" "unprognostic (7.72e-2)" "unprognostic (1.67e-1)" "unprognostic (5.53e-2)" "unprognostic (5.10e-2)" "unprognostic (2.87e-1)" "unprognostic (2.07e-1)" "unprognostic (3.18e-3)" "unprognostic (3.65e-1)" "unprognostic (2.62e-1)" "unprognostic (1.97e-1)" "unprognostic (1.52e-2)" ENO1 "ENO1L1, MBP-1, MPB1, PPH" ENSG00000074800 "Enolase 1" P06733 1 8861000-8879190 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Plasminogen activation, Transcription, Transcription regulation" "DNA-binding, Lyase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 2123.3;Esophageal basal cells: 2585.6;Esophageal suprabasal cells: 2329.2;Extravillous trophoblasts: 2438.6;Migrating cytotrophoblasts: 2045.2;Müller glia: 2322.9;Ocular epithelial cells: 1811.1" "Cell type enhanced" "Detected in all" "Basal cells: 2585.6;Glial cells: 2322.9;Suprabasal cells: 2329.2;Trophoblast cells: 2438.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB018614, HPA068284, HPA068721, CAB069394, CAB080034" Supported Enhanced "Plasma membrane,Cytosol" NA NA 280000000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 95 "Plasma membrane, Cytosol" "CAB018614: , CAB069394: , CAB080034: , HPA068284: , HPA068721: " "potential prognostic unfavorable (1.29e-4)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (1.73e-1)" "unprognostic (5.66e-3)" "unprognostic (2.31e-3)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (3.80e-2)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (7.17e-7)" "potential prognostic favorable (1.76e-5)" "unprognostic (1.36e-2)" "unprognostic (1.91e-2)" "validated prognostic unfavorable (8.23e-8)" "validated prognostic unfavorable (1.25e-8)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (1.23e-3)" "unprognostic (3.51e-1)" "unprognostic (1.16e-2)" "unprognostic (7.15e-3)" "unprognostic (2.84e-2)" "unprognostic (6.59e-3)" "unprognostic (4.28e-2)" "unprognostic (9.51e-2)" "unprognostic (1.93e-1)" "unprognostic (1.21e-2)" "unprognostic (7.46e-2)" "unprognostic (7.70e-2)" "unprognostic (2.82e-1)" "unprognostic (2.81e-1)" "unprognostic (6.99e-2)" ENO2 NSE ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 857.9;retina: 1573.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 165.6;Brain inhibitory neurons: 124.1;Cone photoreceptor cells: 360.2;Other brain neurons: 131.7;Retinal bipolar cells: 164.1;Retinal horizontal cells: 198.3;Rod photoreceptor cells: 468.7" "Cell type enriched" "Detected in many" 9 "Neuronal cells: 468.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 9.9;MAIT T-cell: 11.4;memory B-cell: 6.8;memory CD4 T-cell: 13.1;memory CD8 T-cell: 11.4;naive B-cell: 4.5;naive CD4 T-cell: 8.2;naive CD8 T-cell: 8.6;neutrophil: 7.0;T-reg: 7.5" "Group enriched" "Detected in many" 7 "B-cells: 6.8;granulocytes: 7.0;T-cells: 13.1" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 979764077.4;Microglia and Neuropil: 759736649.3;Neurons: 593457473.9" "Tissue enriched" "Detected in all" "cerebral cortex: 1520840751.0" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Enhanced "Plasma membrane,Cytosol" NA NA 47000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 79: Photoreceptor cells - Phototransduction" 12 "Plasma membrane, Cytosol" "CAB000063: , CAB073539: , CAB079023: , HPA068284: , HPA068721: " "potential prognostic favorable (6.50e-4)" "unprognostic (2.31e-1)" "unprognostic (1.22e-1)" "unprognostic (4.55e-2)" "unprognostic (1.57e-3)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (9.52e-4)" "unprognostic (2.33e-1)" "unprognostic (1.73e-2)" "unprognostic (4.55e-3)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (3.11e-3)" "unprognostic (1.61e-2)" "unprognostic (1.03e-3)" "unprognostic (1.45e-1)" "unprognostic (8.18e-2)" "unprognostic (3.68e-2)" "unprognostic (2.06e-1)" "unprognostic (2.21e-1)" "unprognostic (1.71e-1)" "unprognostic (1.32e-1)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (6.28e-4)" "unprognostic (5.19e-2)" "unprognostic (1.25e-1)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (9.28e-2)" "unprognostic (3.58e-1)" "unprognostic (1.14e-2)" "unprognostic (9.17e-2)" ENO3 ENSG00000108515 "Enolase 3" P13929 17 4948092-4957131 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 27 "skeletal muscle: 13830.4;tongue: 10054.3" "Cell type enhanced" "Detected in many" "Adipocytes: 62.2;Cardiomyocytes: 212.4;Epicardial cells: 150.1;Mesothelial cells: 87.0;Myonuclei: 163.8;Plasma cells: 82.2;Thymic myoid cells: 444.6;Thymocytes: 65.2" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 150.1;Myocytes: 212.4;Stromal cells: 444.6" "Cell type enhanced" "Detected in many" "upper rhombic lip: 12.2" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 64.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 3445891036.6" "Tissue enriched" "Detected in all" "skeletal muscle: 2887512549.4" "HPA000793, HPA068284, HPA068721" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 65000000 "Cluster 29: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Plasma membrane, Cytosol" "HPA000793: , HPA068284: , HPA068721: " "unprognostic (4.90e-3)" "unprognostic (1.07e-1)" "unprognostic (1.45e-1)" "unprognostic (2.83e-2)" "unprognostic (3.41e-3)" "unprognostic (2.84e-3)" "unprognostic (5.13e-2)" "unprognostic (1.93e-1)" "unprognostic (1.05e-1)" "unprognostic (5.96e-2)" "unprognostic (4.88e-3)" "unprognostic (6.38e-2)" "unprognostic (1.72e-2)" "unprognostic (5.00e-2)" "unprognostic (9.82e-2)" "unprognostic (1.01e-2)" "unprognostic (6.83e-2)" "unprognostic (1.53e-2)" "unprognostic (2.48e-2)" "unprognostic (1.84e-1)" "unprognostic (8.99e-3)" "unprognostic (2.52e-3)" "unprognostic (1.23e-3)" "unprognostic (1.44e-1)" "unprognostic (2.04e-2)" "unprognostic (1.85e-1)" "unprognostic (4.59e-2)" "unprognostic (1.69e-2)" "unprognostic (1.18e-1)" "unprognostic (2.77e-2)" "unprognostic (3.94e-1)" ENPP5 ENSG00000112796 "Ectonucleotide pyrophosphatase/phosphodiesterase family member 5" Q9UJA9 6 46159185-46170980 "Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "epididymis: 230.1" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 394.7;Müller glia: 132.7;Myonuclei: 73.6;Myosatellite cells: 82.4;Pituicytes/FSCs: 205.7;Prostatic glandular cells: 77.9;Retinal pigment epithelial cells: 76.7;Sertoli cells: 114.0" "Cell type enhanced" "Detected in many" "Glial cells: 205.7;Reproductive supporting cells: 394.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.9" "Lineage enriched" "Detected in many" 5 "T-cells: 14.9" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Stomach - Parietal cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 2079125.8" "Tissue enhanced" "Detected in some" "cerebral cortex: 2137393.2" HPA016902 Enhanced Approved Nucleoplasm,Cytosol "Intracellular and membrane" Enzyme NA NA 340000 "Cluster 1: T-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 3 Cytosol Nucleoplasm "HPA016902: " "unprognostic (2.79e-2)" "unprognostic (3.53e-2)" "unprognostic (1.75e-2)" "unprognostic (7.08e-2)" "unprognostic (6.10e-2)" "unprognostic (1.51e-2)" "unprognostic (9.15e-2)" "unprognostic (1.57e-1)" "unprognostic (1.73e-1)" "unprognostic (9.97e-3)" "potential prognostic favorable (6.39e-11)" "unprognostic (1.03e-3)" "unprognostic (8.20e-3)" "unprognostic (2.06e-1)" "unprognostic (1.08e-1)" "potential prognostic favorable (9.71e-4)" "unprognostic (3.39e-3)" "unprognostic (3.72e-3)" "unprognostic (1.35e-1)" "unprognostic (3.11e-1)" "unprognostic (1.25e-2)" "unprognostic (1.20e-2)" "unprognostic (1.09e-1)" "unprognostic (1.40e-1)" "unprognostic (1.73e-2)" "unprognostic (5.66e-2)" "unprognostic (3.22e-1)" "unprognostic (6.38e-2)" "unprognostic (4.97e-2)" "unprognostic (2.24e-1)" "unprognostic (5.52e-2)" ENPP6 MGC33971 ENSG00000164303 "Ectonucleotide pyrophosphatase/phosphodiesterase 6" Q6UWR7 4 184088706-184221230 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 27.6;kidney: 28.6;ovary: 15.2" "Group enriched" "Detected in many" 4 "Oligodendrocytes: 110.2;Peritubular myoid cells: 52.1;Pituitary stem cells: 46.6;Proximal tubule cells: 118.1" "Group enriched" "Detected in many" 4 "Glial cells: 110.2;Renal nephron cells: 118.1;Stem cells: 46.6;Stromal cells: 52.1" "Group enriched" "Detected in all" 7 "committed oligodendrocyte precursor: 169.7;fibroblast: 140.7;oligodendrocyte: 159.1" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 5.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 1.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Astrocytes and Neuropil: 98682642.6" "Group enriched" "Detected in many" "cerebral cortex: 151967581.8;ovary: 105154532.8" "HPA042740, HPA069197" Enhanced Approved "Golgi apparatus" "Intracellular and membrane" Enzyme NA NA 51000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 "Golgi apparatus" "HPA042740: , HPA069197: " "unprognostic (2.71e-1)" "unprognostic (2.29e-1)" "unprognostic (3.34e-1)" "unprognostic (1.50e-2)" "unprognostic (2.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" ENSA "ARPP-19e, MGC4319, MGC78563, MGC8394" ENSG00000143420 "Endosulfine alpha" O43768 1 150600851-150629612 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1268.4;Esophageal suprabasal cells: 1066.1;Neutrophils: 759.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1268.4;Suprabasal cells: 1066.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 10878503.9" "Low tissue specificity" "Detected in all" HPA051294 Uncertain Approved Nucleoplasm,Nucleoli,Microtubules,Cytosol NA NA 1100000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 3 "Nucleoplasm, Nucleoli" "Microtubules, Cytosol" "HPA051294: " "unprognostic (2.60e-1)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (5.68e-2)" "unprognostic (1.12e-1)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "unprognostic (1.94e-1)" "unprognostic (2.28e-3)" "unprognostic (2.67e-1)" "unprognostic (1.74e-3)" "unprognostic (1.39e-2)" "unprognostic (3.07e-2)" "unprognostic (3.11e-1)" "unprognostic (7.57e-3)" "unprognostic (2.46e-2)" "unprognostic (3.75e-2)" "unprognostic (3.50e-2)" "unprognostic (1.73e-2)" "unprognostic (5.80e-2)" "unprognostic (5.36e-2)" "unprognostic (1.23e-1)" "unprognostic (1.22e-1)" "unprognostic (7.02e-2)" "unprognostic (2.56e-2)" "unprognostic (2.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.76e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (3.93e-2)" "unprognostic (2.73e-1)" ENSG00000111780 ENSG00000111780 "Novel protein" 12 120438198-120460006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 22.9;Colonocytes: 56.0;Enteric stem cells: 30.4;Enteric transient amplifying cells: 43.3;Enterocytes: 63.0;Epididymal clear cells: 20.4;Goblet cells: 28.6;Parietal cells: 26.5" "Cell type enhanced" "Detected in many" "Enterocytes: 63.0;Proliferating cells: 43.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA062394 Uncertain Approved "Mitochondria,Principal piece" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Mitochondria "Principal piece" "HPA062394: " "unprognostic (3.53e-1)" "unprognostic (3.33e-1)" "unprognostic (9.91e-2)" "unprognostic (5.89e-2)" ENSG00000173867 ENSG00000173867 "Novel transcript" 15 88459501-88546585 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 29.1;Cardiomyocytes: 93.6;Epicardial cells: 18.2;Thyrotrophs: 13.2" "Cell type enhanced" "Detected in many" "Adipocytes: 29.1;Myocytes: 93.6" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" HPA048873 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 75: Ovary - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA048873: " "unprognostic (5.81e-2)" "unprognostic (6.12e-2)" ENSG00000197991 ENSG00000197991 "Novel protein" 13 61409858-61427849 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "Cytokinetic bridge" "HPA062669: " "unprognostic (5.74e-2)" "unprognostic (7.91e-3)" ENSG00000198211 ENSG00000198211 "Novel protein (MC1R-TUBB3 readthrough)" 16 89919165-89936092 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "testis: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.9" "CAB011512, HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB011512: , HPA043640: , HPA046280: " "unprognostic (5.56e-2)" "unprognostic (3.64e-1)" ENSG00000225528 ENSG00000225528 "Novel protein similar to translation machinery associated 7 homolog (S. cerevisiae) TMA7" 22 39960397-39964905 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Tissue enhanced" "Detected in some" "bone marrow: 1.1;lymphoid tissue: 3.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Adipose visceral - T-cells, Thyroid gland - T-cells" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 26: Keratinocytes - Keratinization" "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: " ENSG00000251569 ENSG00000251569 "Novel protein" 2 169479480-169525922 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "retina: 16.6;testis: 8.0" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 2.2;Gastric chief cells: 2.2;Gonadotrophs: 2.0;Myonuclei: 5.4;Parietal cells: 5.3;Respiratory ciliated cells: 1.8;Thymic myoid cells: 9.5" "Cell type enhanced" "Detected in some" "Gastric glandular cells: 5.3;Myocytes: 5.4;Stromal cells: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.2" HPA046125 Uncertain Approved "Primary cilium,Basal body,Cytosol,Acrosome,Perinuclear theca" NA NA "Cluster 42: Retina - Visual perception" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Basal body, Cytosol, Acrosome" "Primary cilium, Perinuclear theca" "HPA046125: " "unprognostic (1.19e-1)" ENSG00000254706 ENSG00000254706 "Novel protein" 1 162365407-162383531 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Cone photoreceptor cells: 31.1;Thyrotrophs: 12.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 53.2;Neuronal cells: 31.1;Pituitary endocrine cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "HPA052251, HPA074060" Uncertain Approved Nucleoplasm NA NA "Cluster 60: Stomach - Digestion" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "HPA052251: , HPA074060: " "unprognostic (1.49e-2)" "unprognostic (4.47e-3)" "unprognostic (8.26e-2)" "unprognostic (1.19e-1)" "unprognostic (3.64e-2)" "unprognostic (3.05e-3)" "unprognostic (1.05e-1)" "unprognostic (1.18e-2)" "unprognostic (7.06e-2)" "unprognostic (1.85e-1)" "unprognostic (1.65e-1)" "unprognostic (6.75e-2)" "unprognostic (4.69e-1)" "unprognostic (4.44e-2)" "unprognostic (2.67e-2)" "unprognostic (4.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.65e-1)" "unprognostic (1.76e-2)" "unprognostic (1.61e-1)" "unprognostic (1.09e-1)" "unprognostic (3.53e-2)" ENSG00000255639 ENSG00000255639 "Novel protein" 12 4649101-4774184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.7;tongue: 17.3" "Cell type enhanced" "Detected in many" "Early spermatids: 98.2;Late primary spermatocytes: 22.6;Oligodendrocyte progenitor cells: 28.0;Retinal bipolar cells: 24.0;Undifferentiated spermatogonia: 56.1" "Cell type enhanced" "Detected in many" "Glial cells: 28.0;Spermatogenic cell types: 98.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA012638, HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Mitochondria Nucleoplasm "HPA012638: , HPA042268: , HPA073212: " "unprognostic (2.27e-1)" "unprognostic (2.29e-1)" "unprognostic (4.63e-2)" "unprognostic (4.67e-2)" "unprognostic (3.21e-2)" "unprognostic (1.61e-1)" "unprognostic (7.27e-3)" "unprognostic (8.09e-2)" "potential prognostic favorable (2.18e-7)" "unprognostic (2.52e-1)" "unprognostic (7.05e-3)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (2.26e-1)" "unprognostic (2.23e-1)" "unprognostic (1.92e-1)" "unprognostic (1.36e-2)" "unprognostic (1.17e-2)" "unprognostic (8.51e-2)" "unprognostic (2.24e-2)" "unprognostic (1.91e-2)" "unprognostic (2.62e-1)" "unprognostic (9.49e-2)" "unprognostic (1.56e-1)" "unprognostic (1.40e-1)" ENSG00000256349 ENSG00000256349 "Novel protein" 11 66509079-66533613 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "retina: 2.1" "Cell type enriched" "Detected in some" 4 "Rod photoreceptor cells: 11.2" "Cell type enriched" "Detected in some" 4 "Neuronal cells: 11.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA058283 Uncertain Approved Midbody Yes NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 79: Photoreceptor cells - Phototransduction" Midbody "HPA058283: " "unprognostic (9.60e-3)" "unprognostic (6.05e-1)" "unprognostic (8.15e-3)" "unprognostic (4.54e-1)" "unprognostic (6.38e-3)" "unprognostic (9.03e-2)" "unprognostic (1.12e-1)" "unprognostic (3.55e-1)" "unprognostic (8.18e-2)" "unprognostic (4.40e-1)" "unprognostic (7.16e-2)" ENSG00000256514 ENSG00000256514 "Novel protein" 11 67351572-67373584 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 8.3;Endometrial glandular cells: 6.3;Endometrial luminal cells: 8.1;Epicardial cells: 15.9;Salivary myoepithelial cells: 7.4" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 15.9;Luminal cells: 8.1;Myocytes: 8.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA078008 Approved "Centriolar satellite" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" "Centriolar satellite" "HPA078008: " "unprognostic (4.55e-2)" "unprognostic (9.10e-2)" "unprognostic (9.98e-2)" "unprognostic (3.89e-2)" "unprognostic (8.18e-3)" "potential prognostic unfavorable (9.12e-4)" "unprognostic (7.64e-2)" "unprognostic (9.95e-2)" "validated prognostic unfavorable (6.40e-6)" "validated prognostic unfavorable (2.30e-5)" "unprognostic (2.62e-1)" "unprognostic (1.50e-1)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (8.97e-5)" "unprognostic (3.40e-1)" "unprognostic (3.05e-3)" "unprognostic (3.03e-1)" "unprognostic (1.55e-1)" "unprognostic (1.27e-2)" "unprognostic (4.56e-2)" "unprognostic (1.34e-1)" "unprognostic (3.78e-2)" "unprognostic (6.08e-2)" "unprognostic (2.78e-1)" "unprognostic (1.76e-1)" "unprognostic (1.62e-1)" "unprognostic (2.53e-1)" ENSG00000260914 ENSG00000260914 "Novel protein" 16 69299682-69322700 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 146.6" "Cell type enhanced" "Detected in some" "Parietal cells: 1.8;Respiratory deuterosomal cells: 1.0" "Cell type enhanced" "Detected in some" "Gastric glandular cells: 1.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA060092 Approved Midbody Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Midbody "HPA060092: " "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (3.82e-2)" "unprognostic (3.11e-2)" "unprognostic (3.02e-2)" "unprognostic (2.79e-3)" "unprognostic (2.28e-1)" "potential prognostic favorable (7.86e-11)" "unprognostic (4.86e-2)" "potential prognostic favorable (3.88e-4)" "unprognostic (1.34e-2)" "unprognostic (4.06e-2)" "unprognostic (2.12e-2)" "unprognostic (2.75e-3)" "unprognostic (1.22e-1)" "unprognostic (1.83e-1)" "unprognostic (2.76e-1)" "unprognostic (6.16e-2)" "unprognostic (5.24e-2)" "unprognostic (3.27e-2)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (9.22e-2)" "unprognostic (1.93e-1)" "unprognostic (1.63e-1)" "unprognostic (6.95e-2)" ENSG00000264668 ENSG00000264668 "Novel protein" 8 143247110-143276403 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "brain: 1.2" "Cell type enhanced" "Detected in many" "Colonocytes: 6.2;Cone photoreceptor cells: 6.2;Hepatic stellate cells: 6.5;Proximal tubule cells: 5.3;Retinal horizontal cells: 6.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: " ENSG00000265118 ENSG00000265118 "Novel protein" 17 31305213-31318831 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 7.8" "Cell type enhanced" "Detected in some" "Adipocytes: 1.9;Cardiomyocytes: 8.4;Epicardial cells: 2.3;Neutrophils: 4.7;NK-cells: 2.1;Oligodendrocytes: 2.7;Plasma cells: 1.3;Retinal horizontal cells: 2.0;T-cells: 1.2" "Cell type enhanced" "Detected in some" "Glial cells: 2.7;Myocytes: 8.4;Neutrophils: 4.7" "Cell type enriched" "Detected in single" 5 "oligodendrocyte: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 221.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Leukemia: 2.0;lymphoma: 2.0;Myeloma: 3.1" HPA045033 Uncertain Approved "Golgi apparatus,Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Golgi apparatus, Vesicles, Plasma membrane, Primary cilium" "Primary cilium transition zone, Cytosol" "HPA045033: " "unprognostic (5.05e-3)" "unprognostic (9.27e-2)" "unprognostic (3.23e-1)" "unprognostic (5.47e-3)" "unprognostic (2.19e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (2.86e-3)" "unprognostic (4.78e-2)" "unprognostic (2.96e-1)" ENSG00000267740 ENSG00000267740 "Novel protein" 19 5866171-5903787 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 5.2;Hematopoietic stem cells: 6.3;Medullary thymic epithelial cells: 4.8;Retinal horizontal cells: 6.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 12.7" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA072209 Approved "Mitochondria,Perinuclear theca,Principal piece,End piece" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" "Mitochondria, End piece" "Perinuclear theca, Principal piece" "HPA072209: " "unprognostic (1.58e-2)" "unprognostic (1.23e-3)" "unprognostic (1.21e-1)" "unprognostic (3.94e-2)" "unprognostic (3.22e-1)" "unprognostic (1.65e-1)" "unprognostic (2.21e-1)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (1.33e-3)" "unprognostic (1.15e-1)" "unprognostic (5.72e-3)" "unprognostic (1.70e-1)" "unprognostic (1.67e-2)" "unprognostic (9.51e-2)" "unprognostic (3.45e-2)" "unprognostic (1.16e-1)" "unprognostic (3.23e-1)" "unprognostic (2.94e-2)" "unprognostic (6.54e-2)" "unprognostic (6.02e-2)" ENSG00000272772 ENSG00000272772 "Novel protein" 5 134157088-134225861 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" HPA053745 Approved "Nucleoplasm,Cytokinetic bridge,Primary cilium,Centrosome,Basal body,Cytosol" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Nucleoplasm, Cytosol" "Cytokinetic bridge, Primary cilium, Centrosome, Basal body" "HPA053745: " "unprognostic (9.29e-3)" "unprognostic (2.69e-1)" "unprognostic (3.45e-1)" "unprognostic (4.53e-2)" ENSG00000274944 ENSG00000274944 "Novel protein" 1 38864501-38881617 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 4.7" "Cell type enhanced" "Detected in some" "Adipocytes: 1.2;Cardiomyocytes: 1.5;Early spermatids: 3.9;Epicardial cells: 2.3;Late primary spermatocytes: 7.9;Thymocytes: 1.7" "Cell type enhanced" "Detected in some" "Barrier epithelial cells: 2.3;Spermatogenic cell types: 7.9" "Cell type enhanced" "Detected in single" "ependymal cell: 1.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "HPA041188, HPA078331" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 37: Non-specific - mRNA processing" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Nucleoplasm Mitochondria "HPA041188: , HPA078331: " "unprognostic (3.98e-2)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (3.58e-1)" "unprognostic (8.51e-2)" "unprognostic (2.51e-1)" "unprognostic (4.60e-3)" "unprognostic (4.42e-1)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (9.62e-2)" "unprognostic (1.19e-2)" "unprognostic (3.16e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (2.95e-3)" "unprognostic (1.26e-1)" "unprognostic (1.21e-1)" "unprognostic (9.02e-3)" "unprognostic (2.50e-2)" "potential prognostic unfavorable (2.23e-4)" "unprognostic (5.08e-2)" "unprognostic (4.04e-3)" ENSG00000276345 ENSG00000276345 Unmapped 2585-11802 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.5" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 19.3;Enterocytes: 60.7;Extravillous trophoblasts: 38.5;Gastric chief cells: 30.6;Kupffer cells: 28.7;Mucous neck cells: 15.7;Paneth cells: 58.0;Parietal cells: 44.2" "Cell type enhanced" "Detected in many" "Enterocytes: 60.7;Gastric glandular cells: 44.2;Mononuclear phagocytes: 28.7;Secretory gland support: 58.0;Trophoblast cells: 38.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" HPA050406 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 35: RS4;11 - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" "Nucleoli fibrillar center, Mitochondria" "HPA050406: " ENSG00000282218 ENSG00000282218 "Novel protein, GOPC-ROS1 readthrough" 6 117318211-117573571 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Adipocytes: 28.7;Alveolar cells type 2: 57.3;Cardiomyocytes: 87.7;Early spermatids: 22.7;Epicardial cells: 79.6;Late spermatids: 70.2;Myonuclei: 28.8;Pericytes: 96.7" "Cell type enhanced" "Detected in many" "Alveolar cells: 57.3;Barrier epithelial cells: 79.6;Mural cells: 96.7;Myocytes: 87.7;Spermatogenic cell types: 70.2" "Cell type enhanced" "Detected in many" "pericyte: 12.2" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebral cortex: 1.2;pons: 1.3;white matter: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA019477 Uncertain Approved "Golgi apparatus,Calyx,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Golgi apparatus, Calyx, Mid piece" "Connecting piece, Principal piece" "HPA019477: " ENSG00000282988 ENSG00000282988 "Novel protein" 6 26195595-26199293 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "esophagus: 4.2;prostate: 4.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 88.4;Colonocytes: 87.7;Erythrocyte progenitors: 66.1;Hematopoietic stem cells: 119.4;Megakaryocyte progenitors: 82.7;Megakaryocyte-Erythroid progenitors: 100.2;Monocyte progenitors: 79.0;Platelets: 89.0;Prostatic club cells: 74.3;Thymocytes: 64.4" "Cell type enhanced" "Detected in many" "Stem cells: 119.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 17.0;neutrophil: 30.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 30.6" "Low cancer specificity" "Detected in many" HPA041189 Uncertain Approved Nucleoplasm NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 65: Non-specific - Cell growth & division" Nucleoplasm "HPA041189: " "unprognostic (5.28e-3)" "unprognostic (3.44e-2)" "potential prognostic favorable (5.77e-4)" "unprognostic (1.23e-1)" "unprognostic (1.17e-1)" "unprognostic (3.29e-2)" "unprognostic (1.08e-2)" "unprognostic (2.00e-1)" "unprognostic (1.42e-1)" "unprognostic (5.38e-2)" "unprognostic (7.38e-2)" "unprognostic (2.42e-1)" "unprognostic (6.97e-2)" "unprognostic (4.54e-1)" "unprognostic (8.01e-2)" ENSG00000285188 ENSG00000285188 "Novel protein" 19 18207961-18255419 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.4;Breast myoepithelial cells: 15.5;Colonocytes: 10.3;Enteric stem cells: 8.5;Enteric transient amplifying cells: 6.3;Epididymal basal cells: 8.0;Foveolar cells: 10.2;Paneth cells: 7.7;pDCs: 11.6" "Cell type enhanced" "Detected in many" "dendritic cells: 11.6;Enterocytes: 10.3;Gastric glandular cells: 10.2;Secretory gland support: 15.5" "Cancer enhanced" "Detected in some" "Thyroid Carcinoma (TCGA): 2.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.1" "HPA048975, HPA054218" Uncertain Approved "Midbody ring,Centrosome,Basal body,Cytosol" Yes NA "Cluster 74: Non-specific - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 20: Non-specific - Transcription regulation" "Centrosome, Basal body, Cytosol" "Midbody ring" "HPA048975: , HPA054218: " "unprognostic (3.53e-1)" "unprognostic (5.82e-2)" "unprognostic (7.27e-2)" "unprognostic (1.41e-1)" ENSG00000285304 ENSG00000285304 "Novel protein" 22 37639693-37666932 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.3;intestine: 7.6" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.3;Myosatellite cells: 1.2;Prostatic hillock cells: 1.3;Thymocytes: 1.7" "Cell type enhanced" "Detected in some" "Barrier epithelial cells: 1.3;Myocytes: 4.3;Stem cells: 1.2;T-cells: 1.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" HPA000757 Approved Approved Cytosol NA NA "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 53: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Cytosol "HPA000757: " "unprognostic (1.90e-2)" "unprognostic (1.70e-3)" "unprognostic (2.51e-1)" "unprognostic (6.54e-2)" "unprognostic (4.30e-2)" "unprognostic (1.03e-1)" "unprognostic (2.48e-1)" "potential prognostic favorable (9.12e-5)" "unprognostic (6.30e-3)" "unprognostic (1.95e-1)" "unprognostic (2.17e-2)" "unprognostic (7.24e-2)" "unprognostic (1.10e-2)" "unprognostic (1.53e-1)" "unprognostic (4.46e-3)" "unprognostic (2.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (5.52e-2)" ENSG00000285827 ENSG00000285827 "Novel protein" 11 118401602-118482737 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.8" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 17.6;Epicardial cells: 6.8" "Group enriched" "Detected in some" 8 "Barrier epithelial cells: 6.8;Myocytes: 17.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" HPA044629 Uncertain Approved "Mitochondria,Principal piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" Mitochondria "Principal piece" "HPA044629: " "unprognostic (1.14e-1)" "unprognostic (5.54e-2)" "unprognostic (1.49e-1)" "unprognostic (1.56e-1)" "unprognostic (2.35e-2)" "unprognostic (2.81e-3)" "unprognostic (6.10e-3)" "unprognostic (1.03e-2)" "unprognostic (3.50e-3)" "unprognostic (1.25e-2)" "unprognostic (1.45e-1)" "unprognostic (8.62e-2)" "unprognostic (8.18e-2)" "unprognostic (5.51e-3)" "unprognostic (1.27e-2)" "unprognostic (7.99e-2)" "unprognostic (2.58e-2)" "potential prognostic favorable (6.69e-4)" "unprognostic (1.33e-2)" "unprognostic (2.94e-2)" "unprognostic (3.54e-1)" "unprognostic (7.02e-2)" ENSG00000285920 ENSG00000285920 "Novel protein" 15 41284007-41380996 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 17 "Astrocytes: 5.4;Bergmann glia: 5.6;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 2.9;Choroid plexus epithelial cells: 7.9;Ependymal cells: 4.4;Microglia: 3.3;Oligodendrocyte progenitor cells: 2.2;Oligodendrocytes: 3.3;Other brain neurons: 2.7" "Group enriched" "Detected in some" 23 "Ciliated cells: 7.9;Glial cells: 5.6;Neuronal cells: 2.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "HPA042904, HPA074847" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: , HPA074847: " "unprognostic (9.15e-2)" "unprognostic (2.32e-1)" "unprognostic (5.94e-2)" "unprognostic (2.55e-2)" "unprognostic (1.33e-1)" "unprognostic (1.59e-1)" "potential prognostic favorable (8.79e-4)" "unprognostic (1.64e-1)" "unprognostic (1.25e-2)" "unprognostic (2.15e-1)" "unprognostic (1.46e-1)" "unprognostic (3.04e-2)" ENSG00000286112 ENSG00000286112 "Kynurenine aminotransferase 1" 9 128819663-128881931 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 14.5;Megakaryocytes: 6.2;Retinal ganglion cells: 7.7" "Cell type enhanced" "Detected in many" "Neuronal cells: 14.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "HPA021176, HPA021177, HPA027736" Uncertain Approved Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 1 Cytosol "HPA021176: , HPA021177: , HPA027736: " ENSG00000286235 ENSG00000286235 "Novel protein" 20 5950949-6039856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 4.3;Monocyte progenitors: 3.5;Myonuclei: 1.8;Neutrophil progenitors: 2.6;Retinal horizontal cells: 2.0;Thymic myoid cells: 2.7" "Cell type enhanced" "Detected in some" "Mononuclear phagocytes: 3.5;Myocytes: 4.3;Neutrophils: 2.6;Stromal cells: 2.7" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 6.2" "HPA045141, HPA066433" Approved Nucleoplasm,Cytosol NA NA "Cluster 61: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm Cytosol "HPA045141: , HPA066433: " "unprognostic (1.09e-2)" "unprognostic (3.08e-1)" "unprognostic (3.34e-1)" "unprognostic (6.71e-2)" "unprognostic (3.00e-2)" "unprognostic (1.72e-2)" "unprognostic (7.90e-3)" ENSG00000288000 ENSG00000288000 "Novel protein" 20 43458054-43541881 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "pDCs: 84.9;Thymocytes: 77.9" "Cell type enhanced" "Detected in many" "dendritic cells: 84.9;T-cells: 77.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059648 Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Midbody ring" "HPA059648: " ENSG00000288684 ENSG00000288684 "Novel protein" 9 32455323-32552603 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 5.4" "Low cancer specificity" "Detected in single" "HPA047193, HPA073217" Uncertain Approved "Plasma membrane,Cytosol" No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA047193: , HPA073217: " "unprognostic (2.76e-2)" ENSG00000289027 ENSG00000289027 "Novel protein" 7 92112176-92245924 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "testis cancer: 10.9" "HPA041325, HPA043508, HPA049606" Uncertain Approved "Endoplasmic reticulum,Vesicles" NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Endoplasmic reticulum, Vesicles" "HPA041325: , HPA043508: , HPA049606: " ENSG00000289700 ENSG00000289700 "Novel protein" 1 209779629-209806179 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 1.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 23.1;Endometrial ciliated cells: 22.8;Endometrial glandular cells: 22.9;Endometrial luminal cells: 45.9;Esophageal apical cells: 27.6;Esophageal basal cells: 24.7;Esophageal suprabasal cells: 35.4;Ocular epithelial cells: 61.5;Salivary basal cells: 29.8;Suprabasal keratinocytes: 39.2;Urothelial cells: 41.2" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 61.5;Basal cells: 29.8;Luminal cells: 45.9;Suprabasal cells: 39.2" "Region enhanced" "Detected in single" "cerebellum: 1.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.9;head and neck cancer: 9.3" "HPA063121, HPA076162" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" Cytosol Nucleoplasm "HPA063121: , HPA076162: " ENSG00000290315 ENSG00000290315 "Novel protein" 3 49024345-49094071 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "pons: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001400, HPA037677, HPA037678" Uncertain Approved "Nucleoplasm,Cytosol,Rods & Rings" NA NA "Cluster 45: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nucleoplasm, Cytosol, Rods & Rings" "HPA001400: , HPA037677: , HPA037678: " ENTPD3 "CD39L3, HB6, NTPDase-3" ENSG00000168032 "Ectonucleoside triphosphate diphosphohydrolase 3" O75355 3 40387184-40428744 "Enzymes, Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.3;cervix: 20.1;salivary gland: 20.8" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 113.8;Breast lactating cells: 93.2;Cardiomyocytes: 88.7;Endometrial glandular cells: 57.8;Lacrimal acinar cells: 50.7;Retinal ganglion cells: 77.3;Urothelial cells: 132.8" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 132.8;Myocytes: 88.7;Neuronal cells: 113.8;Secretory cells: 93.2" "Cell type enhanced" "Detected in all" "CGE interneuron: 185.4;medium spiny neuron: 221.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "plasmacytoid DC: 3.5" "Lineage enriched" "Detected in single" 7 "dendritic cells: 3.5" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 18.5" "Colon - Colon enteroendocrine cells, Heart muscle - Smooth muscle cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Pancreatic islets: 5425609.1;Smooth muscle cells: 4218504.1" "Tissue enhanced" "Detected in many" "cerebral cortex: 5468144.1;salivary gland: 5074672.7" HPA071802 Approved Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 1 Cytosol "HPA071802: " "unprognostic (1.17e-2)" "unprognostic (8.44e-2)" "unprognostic (1.46e-1)" "unprognostic (3.76e-3)" "unprognostic (8.82e-2)" "unprognostic (1.58e-1)" "unprognostic (8.17e-2)" "unprognostic (8.19e-2)" "unprognostic (2.09e-2)" "unprognostic (3.43e-2)" "unprognostic (1.89e-1)" "unprognostic (3.55e-2)" "unprognostic (6.27e-3)" "unprognostic (1.06e-2)" "unprognostic (7.60e-2)" "unprognostic (1.00e-1)" "potential prognostic favorable (3.41e-5)" "unprognostic (1.88e-1)" "unprognostic (3.89e-1)" "unprognostic (7.58e-2)" "unprognostic (8.25e-2)" "unprognostic (3.45e-1)" "unprognostic (2.09e-1)" "unprognostic (9.83e-3)" EPAS1 "bHLHe73, HIF2A, HLF, MOP2, PASD2" ENSG00000116016 "Endothelial PAS domain protein 1" Q99814 2 46293667-46386697 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Angiogenesis, Differentiation, Host-virus interaction, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 388.8;placenta: 419.0" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 583.5;Extravillous trophoblasts: 1049.1;Pericytes: 619.2;Respiratory basal cells: 657.3;Respiratory secretory cells: 722.3;Syncytiotrophoblasts: 996.6;Vascular endothelial cells: 1356.1" "Cell type enhanced" "Detected in many" "Endothelial cells: 1356.1;Trophoblast cells: 1049.1" "Group enriched" "Detected in all" 4 "endothelial cell: 1673.4;pericyte: 727.1;vascular associated smooth muscle cell: 610.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 231.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18 "basophil: 20.7;eosinophil: 8.4" "Lineage enriched" "Detected in single" 26 "granulocytes: 20.7" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031200, HPA069697" Supported "Nucleoplasm,Actin filaments,Cytokinetic bridge,Cytosol" Yes NA "Cluster 46: Basophils - Proteolysis" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 43 Nucleoplasm "Actin filaments, Cytokinetic bridge, Cytosol" "HPA031200: , HPA069697: " "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (1.55e-2)" "unprognostic (1.03e-2)" "unprognostic (1.42e-1)" "unprognostic (2.07e-2)" "unprognostic (9.03e-2)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (9.01e-2)" "unprognostic (1.67e-1)" "validated prognostic favorable (5.01e-10)" "validated prognostic favorable (1.32e-4)" "unprognostic (7.43e-2)" "unprognostic (1.03e-1)" "unprognostic (3.50e-2)" "unprognostic (5.04e-2)" "unprognostic (7.29e-2)" "unprognostic (1.65e-1)" "unprognostic (3.21e-2)" "unprognostic (9.83e-2)" "unprognostic (8.80e-2)" "unprognostic (6.22e-2)" "unprognostic (8.41e-2)" "unprognostic (2.10e-1)" "unprognostic (5.28e-2)" "unprognostic (1.40e-1)" "unprognostic (6.29e-2)" "unprognostic (1.49e-2)" "unprognostic (1.12e-1)" "unprognostic (1.22e-2)" "unprognostic (1.42e-1)" EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 74.1" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 900.5;Neutrophils: 878.8;Retinal bipolar cells: 769.2;Rod photoreceptor cells: 1120.2" "Cell type enhanced" "Detected in all" "Neuronal cells: 1120.2;Neutrophils: 878.8" "Cell type enhanced" "Detected in all" "upper rhombic lip: 737.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 92.6" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 142.2" "Cell type enhanced" "Detected in all" "Alveolar cell types: 289988838.2" "Low tissue specificity" "Detected in all" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 7000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 15: Non-specific - Transcription" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 15 "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: , HPA028096: , HPA028412: , HPA028414: " "unprognostic (1.43e-1)" "unprognostic (1.88e-1)" "unprognostic (2.96e-1)" "unprognostic (2.00e-2)" "unprognostic (3.88e-2)" "unprognostic (3.56e-2)" "unprognostic (6.99e-2)" "unprognostic (1.51e-3)" "unprognostic (4.16e-3)" "unprognostic (6.60e-2)" "potential prognostic favorable (1.69e-4)" "unprognostic (1.03e-1)" "unprognostic (2.88e-2)" "unprognostic (3.65e-3)" "unprognostic (5.89e-2)" "unprognostic (3.64e-2)" "unprognostic (2.47e-1)" "unprognostic (9.97e-2)" "unprognostic (7.19e-3)" "unprognostic (6.86e-3)" "unprognostic (7.20e-2)" "unprognostic (6.31e-2)" "unprognostic (2.79e-1)" "unprognostic (7.99e-2)" "unprognostic (1.38e-2)" "unprognostic (3.19e-2)" "unprognostic (1.97e-1)" "unprognostic (5.14e-2)" "unprognostic (1.80e-1)" "unprognostic (4.17e-2)" "unprognostic (2.77e-1)" EPB41L1 "4.1N, KIAA0338" ENSG00000088367 "Erythrocyte membrane protein band 4.1 like 1" Q9H4G0 20 36091504-36232799 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 432.7;Distal convoluted tubule cells: 287.7;Loop of henle epithelial cells: 288.0;Renal connecting tubule cells: 373.6" "Cell type enhanced" "Detected in many" "Ductal cells: 373.6;Neuronal cells: 432.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 93360296.1;Microglia and Neuropil: 109598531.5;Neurons: 96712673.3" "Tissue enriched" "Detected in many" "cerebral cortex: 260930486.4" "HPA054104, HPA056817" Enhanced Supported "Plasma membrane" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 36: Brain & Liver - Signaling" "Cluster 1: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 19 "Plasma membrane" "HPA054104: , HPA056817: " "potential prognostic favorable (6.57e-5)" "unprognostic (1.36e-1)" "unprognostic (9.41e-2)" "unprognostic (1.49e-2)" "unprognostic (1.94e-2)" "unprognostic (3.52e-2)" "unprognostic (1.84e-2)" "unprognostic (1.63e-2)" "unprognostic (3.64e-1)" "unprognostic (1.70e-1)" "validated prognostic favorable (4.67e-10)" "validated prognostic favorable (3.24e-5)" "unprognostic (2.14e-2)" "unprognostic (5.27e-2)" "unprognostic (6.44e-2)" "unprognostic (4.63e-2)" "unprognostic (2.04e-1)" "unprognostic (1.25e-1)" "unprognostic (1.84e-3)" "unprognostic (6.19e-3)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (8.33e-4)" "unprognostic (5.34e-2)" "unprognostic (3.05e-1)" "unprognostic (1.78e-1)" "unprognostic (1.65e-1)" "unprognostic (2.29e-3)" "unprognostic (1.62e-1)" "unprognostic (2.56e-1)" "unprognostic (2.65e-1)" "unprognostic (7.94e-2)" EPB41L3 "4.1B, DAL1, KIAA0987" ENSG00000082397 "Erythrocyte membrane protein band 4.1 like 3" Q9Y2J2 18 5392381-5630700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 461.6;Enterocytes: 471.9;Esophageal apical cells: 440.7;Kupffer cells: 452.0;Late spermatids: 459.7;Macrophages: 479.3;monocytes: 600.8;Proximal tubule cells: 557.9;Retinal amacrine cells: 527.1;Retinal ganglion cells: 591.0;Sertoli cells: 461.0;Syncytiotrophoblasts: 542.6" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 600.8;Neuronal cells: 591.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.7;non-classical monocyte: 12.5" "Lineage enriched" "Detected in many" 5 "monocytes: 12.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Kidney - Proximal tubular cells, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 262675903.1;Microglia and Neuropil: 300070807.0" "Tissue enriched" "Detected in all" "cerebral cortex: 612945922.3" HPA028605 Enhanced Supported "Plasma membrane,Cell Junctions,Primary cilium,Basal body" NA NA 380000 "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 59 "Plasma membrane, Cell Junctions" "Primary cilium, Basal body" "HPA028605: " "unprognostic (1.77e-1)" "unprognostic (1.37e-2)" "unprognostic (9.32e-2)" "unprognostic (2.51e-1)" "unprognostic (1.95e-1)" "unprognostic (5.93e-2)" "unprognostic (2.30e-1)" "unprognostic (5.00e-2)" "unprognostic (8.30e-3)" "unprognostic (4.56e-2)" "potential prognostic favorable (2.61e-5)" "unprognostic (4.08e-2)" "unprognostic (1.48e-2)" "unprognostic (1.00e-1)" "unprognostic (9.99e-2)" "unprognostic (1.83e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-1)" "unprognostic (2.18e-3)" "unprognostic (1.95e-1)" "unprognostic (2.51e-2)" "unprognostic (7.71e-2)" "unprognostic (8.21e-2)" "unprognostic (2.88e-2)" "unprognostic (2.58e-1)" "unprognostic (1.62e-1)" "unprognostic (2.01e-3)" "unprognostic (2.05e-1)" "unprognostic (8.77e-3)" "unprognostic (7.64e-2)" EPC1 Epl1 ENSG00000120616 "Enhancer of polycomb homolog 1" Q9H2F5 10 32267751-32378798 "Predicted intracellular proteins" "Differentiation, Growth regulation, Spermatogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 141.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 241388.1;Neurons: 253735.3" "Group enriched" "Detected in some" 13922 "fallopian tube: 2190277.8;lymphoid tissue: 594105.7" "HPA005811, HPA071652" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 9: T-cells - Adaptive immunity: Regulation" 34 Nucleoplasm "Nucleoli, Nuclear bodies" "HPA005811: , HPA071652: " "unprognostic (4.16e-3)" "unprognostic (3.94e-2)" "unprognostic (2.83e-1)" "unprognostic (2.63e-1)" "unprognostic (1.91e-2)" "unprognostic (6.14e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (3.25e-5)" "potential prognostic favorable (3.44e-4)" "unprognostic (2.60e-2)" "validated prognostic favorable (3.87e-5)" "validated prognostic favorable (2.98e-4)" "unprognostic (5.97e-2)" "unprognostic (2.47e-3)" "unprognostic (6.54e-3)" "unprognostic (1.45e-2)" "unprognostic (2.89e-1)" "unprognostic (2.45e-1)" "unprognostic (2.54e-1)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-2)" "unprognostic (6.47e-3)" "unprognostic (4.42e-1)" "unprognostic (4.07e-1)" "unprognostic (3.13e-2)" "unprognostic (2.95e-3)" "unprognostic (1.31e-1)" "unprognostic (1.09e-1)" "unprognostic (6.87e-2)" "unprognostic (3.04e-1)" EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 21.9" "Cell type enhanced" "Detected in many" "Enteric stem cells: 337.1;Enteric transient amplifying cells: 209.9;Late spermatids: 366.1;Neuroendocrine cells: 100.4;Paneth cells: 425.4;Pituicytes/FSCs: 100.3;Retinal amacrine cells: 117.1" "Cell type enhanced" "Detected in many" "Proliferating cells: 209.9;Secretory gland support: 425.4;Spermatogenic cell types: 366.1;Stem cells: 337.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 74.6;Rectum Adenocarcinoma (TCGA): 72.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 4292596.0;Collecting ducts: 1304312.4;Microglia and Neuropil: 1842918.3;Neurons: 2387934.2;Oocytes: 1255915.4" "Tissue enhanced" "Detected in many" "cerebral cortex: 5978716.6;intestine: 7429025.7" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor No No 520000 "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 25 "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: " "unprognostic (8.42e-2)" "unprognostic (1.03e-2)" "unprognostic (8.41e-2)" "unprognostic (6.28e-3)" "unprognostic (1.64e-3)" "unprognostic (6.59e-3)" "unprognostic (9.17e-2)" "unprognostic (6.57e-2)" "unprognostic (4.09e-2)" "unprognostic (1.04e-2)" "unprognostic (2.24e-2)" "unprognostic (9.05e-3)" "unprognostic (6.22e-3)" "unprognostic (1.39e-1)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (6.93e-3)" "unprognostic (5.85e-3)" "unprognostic (6.96e-3)" "unprognostic (3.58e-3)" "unprognostic (2.53e-2)" "unprognostic (2.23e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.87e-3)" "unprognostic (3.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (6.19e-2)" "unprognostic (1.31e-2)" "unprognostic (7.58e-2)" EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 366.6;Esophageal apical cells: 237.5;Kupffer cells: 254.2;Late spermatids: 315.0" "Cell type enhanced" "Detected in all" "Enterocytes: 366.6;Spermatogenic cell types: 315.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 9500831.5;Microglia and Neuropil: 11713883.2" "Tissue enriched" "Detected in all" "cerebral cortex: 59242802.3" "CAB009729, HPA061136, HPA071503" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 1: Enterocytes - Absorption and Digestion" 33 "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: , HPA061136: , HPA071503: " "unprognostic (3.79e-2)" "unprognostic (1.25e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-2)" "unprognostic (4.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-1)" "unprognostic (1.62e-1)" "unprognostic (3.20e-1)" "unprognostic (2.91e-2)" "unprognostic (1.38e-1)" "unprognostic (4.54e-1)" "unprognostic (2.56e-3)" "unprognostic (1.81e-3)" "unprognostic (7.60e-2)" "potential prognostic unfavorable (6.45e-4)" "unprognostic (8.04e-3)" "unprognostic (1.57e-1)" "unprognostic (1.71e-1)" "unprognostic (2.63e-1)" "unprognostic (1.27e-1)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.33e-1)" "unprognostic (4.90e-2)" "unprognostic (3.34e-2)" "unprognostic (1.16e-2)" "unprognostic (1.46e-1)" "unprognostic (1.58e-3)" "unprognostic (7.22e-2)" ERCC3 "BTF2, RAD25, Ssl2, XPB" ENSG00000163161 "ERCC excision repair 3, TFIIH core complex helicase subunit" P19447 2 127257290-127294166 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase, Isomerase" "Cancer-related genes, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Ichthyosis, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 5713312.6" "Group enriched" "Detected in many" "cerebral cortex: 143263.4;lung: 274967.7;lymphoid tissue: 237617.1" "CAB037153, HPA046077" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 92 Nucleoplasm Vesicles "CAB037153: , HPA046077: " "unprognostic (6.91e-3)" "unprognostic (6.88e-2)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" "unprognostic (2.67e-1)" "unprognostic (2.29e-3)" "unprognostic (5.08e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (2.17e-5)" "unprognostic (1.68e-2)" "unprognostic (5.78e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (7.64e-2)" "unprognostic (1.04e-1)" "unprognostic (5.39e-2)" "unprognostic (1.86e-1)" "unprognostic (1.12e-1)" "unprognostic (2.54e-1)" "unprognostic (1.74e-1)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (2.29e-1)" "unprognostic (1.35e-1)" "unprognostic (2.41e-1)" "unprognostic (5.76e-2)" "unprognostic (4.12e-2)" "unprognostic (2.13e-1)" "unprognostic (1.12e-1)" "unprognostic (4.51e-2)" ERCC6 "ARMD5, CKN2, CSB, RAD26" ENSG00000225830 "ERCC excision repair 6, chromatin remodeling factor" "P0DP91, Q03468" 10 49454168-49539538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Helicase, Hydrolase" "Age-related macular degeneration, Cancer-related genes, Cataract, Cockayne syndrome, Deafness, Disease variant, Dwarfism, Intellectual disability, Premature ovarian failure, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 159.9" "Cell type enhanced" "Detected in all" "Ciliated cells: 159.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 1622771.9" "Not detected" "Not detected" HPA071297 Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 64 Nucleoplasm "Nuclear bodies" "HPA071297: " "potential prognostic unfavorable (4.61e-4)" "unprognostic (7.93e-2)" "unprognostic (1.35e-1)" "unprognostic (1.13e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-3)" "unprognostic (1.20e-1)" "potential prognostic favorable (5.20e-4)" "unprognostic (1.35e-1)" "unprognostic (6.34e-2)" "validated prognostic favorable (5.61e-5)" "validated prognostic favorable (8.76e-4)" "unprognostic (2.84e-1)" "unprognostic (9.98e-2)" "unprognostic (3.63e-1)" "unprognostic (3.57e-1)" "unprognostic (1.82e-1)" "unprognostic (1.34e-1)" "unprognostic (4.97e-2)" "potential prognostic unfavorable (3.85e-4)" "unprognostic (4.97e-3)" "unprognostic (4.72e-3)" "unprognostic (7.77e-2)" "unprognostic (5.75e-2)" "unprognostic (3.77e-2)" "unprognostic (4.51e-2)" "unprognostic (8.02e-2)" "unprognostic (2.52e-1)" "unprognostic (1.27e-1)" "unprognostic (2.45e-1)" ERCC6L "FLJ20105, PICH, RAD26L" ENSG00000186871 "ERCC excision repair 6 like, spindle assembly checkpoint helicase" Q2NKX8 X 72204657-72239027 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.0;lymphoid tissue: 3.3" "Cell type enhanced" "Detected in many" "Adipocytes: 15.0;Cardiomyocytes: 32.1;Epicardial cells: 31.8;Erythrocyte progenitors: 24.1;Fibro-adipogenic progenitors: 16.9;Megakaryocyte progenitors: 13.6;Monocyte progenitors: 14.8;Myonuclei: 14.0;Myosatellite cells: 10.8" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 31.8;Erythrocytes: 24.1;Myocytes: 32.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 15.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 1.7" "Lineage enriched" "Detected in single" 4 "NK-cells: 1.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 3959 "Granulosa cells: 619268.7;Neutrophils: 343918.1;Oocytes: 224534.7" "Group enriched" "Detected in some" 7430 "bone marrow: 618608.9;ovary: 867435.2" HPA050492 Approved Uncertain Nucleoplasm,Centrosome,Cytosol No Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 15 Centrosome "Nucleoplasm, Cytosol" "HPA050492: " "unprognostic (6.11e-2)" "unprognostic (1.18e-3)" "unprognostic (1.11e-1)" "unprognostic (9.01e-2)" "unprognostic (2.43e-1)" "unprognostic (2.08e-1)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (4.68e-1)" "validated prognostic unfavorable (1.43e-4)" "validated prognostic unfavorable (1.95e-5)" "unprognostic (2.04e-2)" "unprognostic (1.54e-1)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (5.13e-3)" "potential prognostic favorable (8.43e-4)" "unprognostic (3.36e-2)" "unprognostic (4.65e-2)" "unprognostic (7.60e-3)" "unprognostic (1.45e-1)" "unprognostic (3.84e-2)" EREG ER ENSG00000124882 Epiregulin O14944 4 74365145-74388749 "Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "bone marrow: 121.5" "Cell type enhanced" "Detected in many" "cDC: 393.0;Esophageal apical cells: 833.0;Hematopoietic stem cells: 947.6;Megakaryocyte progenitors: 935.3;Megakaryocyte-Erythroid progenitors: 1194.8;Monocyte progenitors: 3242.6;monocytes: 3369.3;Neutrophil progenitors: 402.2" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 833.0;Megakaryocytes: 1194.8;Mononuclear phagocytes: 3369.3;Stem cells: 947.6" "Group enriched" "Detected in some" 36 "CGE interneuron: 10.8;leukocyte: 21.9" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 18.3;Rectum Adenocarcinoma (TCGA): 23.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 126.8" "Adipose visceral - Neutrophils, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047186, HPA054373" Approved Vesicles,Cytosol "Secreted to blood" "Growth factor" NA NA 46000 "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 Vesicles Cytosol "HPA047186: , HPA054373: " "unprognostic (7.67e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (8.82e-6)" "unprognostic (4.04e-2)" "unprognostic (9.73e-3)" "unprognostic (2.06e-2)" "unprognostic (6.06e-2)" "unprognostic (5.07e-2)" "potential prognostic unfavorable (5.68e-4)" "unprognostic (6.14e-3)" "potential prognostic unfavorable (7.21e-4)" "unprognostic (2.95e-3)" "validated prognostic unfavorable (9.01e-5)" "validated prognostic unfavorable (3.99e-4)" "unprognostic (1.92e-2)" "potential prognostic favorable (2.50e-4)" "unprognostic (1.23e-2)" "unprognostic (4.65e-1)" ERF "PE-2, PE2" ENSG00000105722 "ETS2 repressor factor" P50548 19 42247569-42255128 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Epicardial cells: 6.8;Epididymal clear cells: 2.0;Fallopian secretory cells: 2.0;Fallopian tube ciliated cells: 1.8;Ocular epithelial cells: 1.7;Schwann cells: 3.7" "Cell type enhanced" "Detected in some" "Barrier epithelial cells: 6.8;Glial cells: 3.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 2630338.9" "Group enriched" "Detected in some" "fallopian tube: 183896.3;ovary: 72515.7" "HPA058532, HPA067952, HPA072144" Approved Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 4: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 27 Nucleoplasm "Nucleoli, Plasma membrane, Cytosol" "HPA058532: , HPA067952: , HPA072144: " "unprognostic (5.96e-2)" "unprognostic (1.62e-2)" "unprognostic (4.04e-2)" "unprognostic (3.23e-3)" "unprognostic (1.68e-2)" "unprognostic (5.36e-3)" "unprognostic (7.73e-2)" "unprognostic (5.69e-2)" "unprognostic (1.54e-1)" "unprognostic (3.37e-1)" "potential prognostic favorable (3.29e-4)" "unprognostic (3.46e-2)" "unprognostic (6.25e-2)" "unprognostic (3.26e-1)" "unprognostic (1.74e-1)" "unprognostic (7.00e-3)" "unprognostic (2.16e-1)" "unprognostic (1.72e-1)" "unprognostic (3.07e-3)" "unprognostic (1.17e-1)" "unprognostic (1.91e-1)" "unprognostic (3.07e-1)" "unprognostic (8.94e-2)" "unprognostic (3.48e-1)" "unprognostic (2.40e-2)" "unprognostic (3.62e-2)" "unprognostic (1.22e-1)" "unprognostic (2.00e-1)" "unprognostic (4.99e-1)" "unprognostic (6.31e-3)" "unprognostic (5.58e-2)" ERI3 "FLJ22943, PINT1, PRNPIP" ENSG00000117419 "ERI1 exoribonuclease family member 3" O43414 1 44221070-44355260 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Late spermatids: 1634.4" "Cell type enriched" "Detected in all" 6 "Spermatogenic cell types: 1634.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 12140573.7" "Tissue enhanced" "Detected in all" "cerebral cortex: 6778563.0" "HPA027147, HPA029895" Approved Approved Nucleoplasm,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Nucleoplasm, Cytosol" "HPA027147: , HPA029895: " "unprognostic (7.57e-2)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (3.15e-5)" "unprognostic (1.66e-2)" "unprognostic (3.60e-2)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" "unprognostic (5.78e-2)" "unprognostic (1.75e-1)" "unprognostic (5.05e-2)" "unprognostic (8.15e-2)" "unprognostic (1.28e-1)" "unprognostic (2.80e-1)" "validated prognostic unfavorable (2.50e-6)" "validated prognostic unfavorable (4.94e-5)" "unprognostic (2.92e-2)" "unprognostic (4.57e-2)" "unprognostic (3.41e-1)" "unprognostic (8.44e-2)" "unprognostic (5.02e-2)" "unprognostic (4.42e-2)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-1)" "unprognostic (5.01e-2)" "unprognostic (7.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.60e-1)" "unprognostic (7.15e-2)" "unprognostic (8.98e-2)" ERICH3 "C1orf173, DKFZp547I048, RP11-653A5.1" ENSG00000178965 "Glutamate rich 3" Q5RHP9 1 74568117-74673792 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.4;fallopian tube: 16.3;testis: 22.6" "Cell type enhanced" "Detected in many" "Early spermatids: 320.0;Endometrial ciliated cells: 283.1;Ependymal cells: 236.5;Epididymal efferent duct ciliated cells: 296.7;Fallopian tube ciliated cells: 554.7;Lactotrophs: 141.6;Late primary spermatocytes: 252.8;Late spermatids: 532.9;Respiratory ciliated cells: 984.9;Thyrotrophs: 140.2" "Group enriched" "Detected in many" 5 "Ciliated cells: 984.9;Spermatogenic cell types: 532.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Rhabdoid: 4.0" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 83646336.3" "Tissue enriched" "Detected in some" "fallopian tube: 124221159.1" "HPA028655, HPA072916" Approved Uncertain "Nuclear membrane,Nucleoli,Endoplasmic reticulum,Primary cilium" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 107: Ciliated cells - Cilia assembly & function" "Nuclear membrane, Endoplasmic reticulum" "Nucleoli, Primary cilium" "HPA028655: , HPA072916: " "unprognostic (1.20e-1)" "unprognostic (7.07e-3)" "unprognostic (3.68e-3)" "unprognostic (7.73e-2)" ERMN "ERMIN, JN, KIAA1189" ENSG00000136541 Ermin Q8TAM6 2 157318631-157327713 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 596.2" "Group enriched" "Detected in some" 28 "Oligodendrocytes: 273.5;Retinal pigment epithelial cells: 716.2" "Group enriched" "Detected in many" 28 "Glial cells: 273.5;Pigment cells: 716.2" "Cell type enriched" "Detected in many" 6 "oligodendrocyte: 407.8" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 19.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Myeloma: 6.3" "Kidney - T-cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Astrocytes and Neuropil: 20453291.8" "Tissue enriched" "Detected in some" "cerebral cortex: 68074762.6" "HPA038295, HPA038296" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 "Plasma membrane" Cytosol "HPA038295: , HPA038296: " "unprognostic (9.27e-2)" "unprognostic (2.74e-2)" "unprognostic (4.79e-2)" "unprognostic (1.25e-1)" "unprognostic (2.02e-1)" "unprognostic (1.63e-1)" "unprognostic (4.96e-3)" "unprognostic (1.03e-1)" "unprognostic (2.29e-1)" "unprognostic (2.81e-2)" "unprognostic (2.01e-1)" "unprognostic (1.64e-3)" "unprognostic (2.89e-2)" "unprognostic (1.66e-1)" "unprognostic (9.28e-2)" ERRFI1 "GENE-33, MIG-6, RALT" ENSG00000116285 "ERBB receptor feedback inhibitor 1" Q9UJM3 1 8004404-8026309 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 695.4;pancreas: 640.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 800.4;Basal keratinocytes: 1275.1;Epididymal basal cells: 806.0;Hepatocytes: 1316.1;Pancreatic acinar cells: 759.6;Proximal tubule cells: 984.2;Thymic myoid cells: 985.7" "Cell type enhanced" "Detected in many" "Basal cells: 1275.1;Hepatocytes: 1316.1" "Cell type enhanced" "Detected in all" "vascular associated smooth muscle cell: 123.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 5 "monocytes: 2.0" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027206, HPA076543" Enhanced Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 28 Cytosol "HPA027206: , HPA076543: " "unprognostic (1.77e-2)" "unprognostic (1.21e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-3)" "unprognostic (6.10e-2)" "unprognostic (1.41e-2)" "unprognostic (4.14e-3)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (2.13e-3)" "unprognostic (3.06e-1)" "unprognostic (5.39e-3)" "unprognostic (2.67e-1)" "unprognostic (7.77e-2)" "unprognostic (1.90e-2)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (2.78e-3)" "unprognostic (2.97e-2)" "unprognostic (1.15e-1)" "unprognostic (2.99e-2)" "unprognostic (1.13e-1)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (8.05e-5)" "unprognostic (4.98e-1)" "unprognostic (2.83e-1)" "potential prognostic favorable (2.69e-4)" "unprognostic (7.00e-2)" "unprognostic (1.37e-3)" "unprognostic (2.99e-1)" "unprognostic (3.30e-2)" "unprognostic (1.12e-1)" ERVV-1 "ENVV1, FLJ32214, HERV-V1" ENSG00000269526 "Endogenous retrovirus group V member 1, envelope" B6SEH8 19 53013921-53016123 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 15 "placenta: 15.1" "Cell type enriched" "Detected in some" 45 "Syncytiotrophoblasts: 385.5" "Cell type enriched" "Detected in some" 256 "Trophoblast cells: 385.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 1.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 2.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 11 "testis cancer: 5.7" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 19 "cerebral cortex: 1924.8" HPA076115 Approved Centrosome,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Cytosol Centrosome "HPA076115: " "unprognostic (1.03e-1)" "unprognostic (3.49e-1)" ERVV-2 ENVV2 ENSG00000268964 "Endogenous retrovirus group V member 2, envelope" B6SEH9 19 53044740-53051680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "placenta: 7.9" "Cell type enriched" "Detected in some" 28 "Syncytiotrophoblasts: 133.2" "Cell type enriched" "Detected in some" 91 "Trophoblast cells: 133.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 3.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "testis cancer: 10.0" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 92 "lymphoid tissue: 9185.0" HPA076115 Approved Centrosome,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Cytosol Centrosome "HPA076115: " "unprognostic (4.19e-1)" "unprognostic (1.21e-1)" ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.6;intestine: 10.3;lymphoid tissue: 7.9;testis: 5.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 42.1;Differentiating spermatogonia: 77.7;Early primary spermatocytes: 127.1;Erythrocyte progenitors: 80.4;Megakaryocyte progenitors: 38.1;Monocyte progenitors: 49.1;Oocytes: 336.2" "Cell type enhanced" "Detected in many" "Erythrocytes: 80.4;Oocytes: 336.2;Spermatogenic cell types: 127.1" "Cell type enhanced" "Detected in some" "hippocampal CA4: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 8331 "Granulosa cells: 833071.3" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 41: Oocytes - Oogenesis" 11 Nucleoplasm "Golgi apparatus, Cell Junctions" "HPA027243: , HPA053679: " "unprognostic (4.54e-2)" "unprognostic (1.97e-1)" "unprognostic (5.63e-2)" "unprognostic (5.73e-2)" "potential prognostic favorable (9.95e-5)" "unprognostic (2.74e-1)" "unprognostic (1.21e-1)" "unprognostic (4.53e-3)" "unprognostic (3.10e-2)" "unprognostic (9.42e-3)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (1.42e-2)" "unprognostic (1.28e-3)" "unprognostic (8.08e-2)" "unprognostic (5.81e-2)" "unprognostic (5.31e-2)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (2.22e-2)" "potential prognostic favorable (2.79e-5)" "unprognostic (3.33e-2)" "unprognostic (2.11e-2)" "unprognostic (5.19e-2)" "unprognostic (2.92e-1)" "unprognostic (2.55e-1)" ESD ENSG00000139684 "Esterase D" P10768 13 46771256-46797420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 428.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA039700 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 8100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 19: Non-specific - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 18 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039700: " "unprognostic (9.36e-2)" "unprognostic (1.85e-1)" "unprognostic (6.90e-2)" "unprognostic (3.07e-2)" "unprognostic (3.46e-2)" "unprognostic (5.67e-1)" "unprognostic (3.84e-2)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (3.99e-5)" "unprognostic (7.44e-2)" "potential prognostic favorable (1.21e-11)" "unprognostic (2.27e-3)" "unprognostic (2.01e-2)" "unprognostic (3.36e-2)" "unprognostic (9.96e-3)" "unprognostic (1.16e-1)" "unprognostic (2.32e-2)" "unprognostic (4.44e-2)" "unprognostic (1.80e-1)" "unprognostic (3.95e-3)" "unprognostic (1.52e-2)" "unprognostic (2.69e-2)" "unprognostic (8.47e-2)" "unprognostic (8.57e-2)" "unprognostic (8.06e-2)" "unprognostic (2.27e-1)" "unprognostic (3.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.42e-1)" "unprognostic (7.23e-2)" "unprognostic (2.62e-1)" ESPN DFNB36 ENSG00000187017 Espin B1AK53 1 6424776-6461367 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing Actin-binding "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 170.3;retina: 109.8;testis: 159.4" "Cell type enhanced" "Detected in many" "Colonocytes: 166.2;Cone photoreceptor cells: 147.0;Early spermatids: 178.3;Enterocytes: 491.5;Hepatocytes: 117.3;Late spermatids: 849.6;Müller glia: 289.5;Proximal tubule cells: 121.5;Rod photoreceptor cells: 183.4;Sertoli cells: 157.8" "Cell type enhanced" "Detected in many" "Enterocytes: 491.5;Glial cells: 289.5;Spermatogenic cell types: 849.6" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 29.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 92.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 4.0" "Group enriched" "Detected in many" "Fallopian tube cells: 1633390.1;Hepatocytes: 2333777.9;Keratinocytes: 3244720.7;Proximal tubules: 4229839.0" "Group enriched" "Detected in some" "bone marrow: 8234871.5;kidney: 6870485.2;liver: 4147291.5" "HPA028674, HPA060220" Enhanced Approved Vesicles NA NA "Cluster 47: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 Vesicles "HPA028674: , HPA060220: " "unprognostic (1.54e-1)" "unprognostic (8.53e-2)" "unprognostic (8.98e-2)" "unprognostic (6.37e-2)" "unprognostic (2.09e-1)" "unprognostic (1.07e-3)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (1.13e-1)" "validated prognostic favorable (2.97e-5)" "validated prognostic favorable (6.16e-5)" "unprognostic (1.50e-3)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (4.42e-1)" "unprognostic (2.44e-2)" "unprognostic (4.40e-2)" "unprognostic (1.03e-1)" "unprognostic (7.11e-3)" "unprognostic (1.69e-1)" "unprognostic (2.57e-2)" "unprognostic (3.49e-1)" "unprognostic (5.87e-2)" "unprognostic (1.71e-1)" "unprognostic (2.58e-1)" "unprognostic (2.92e-1)" "unprognostic (3.84e-2)" "unprognostic (3.82e-2)" ESRRA "ERR1, ERRa, ERRalpha, ESRL1, NR3B1" ENSG00000173153 "Estrogen related receptor alpha" P11474 11 64305497-64316743 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.8" "Cell type enhanced" "Detected in many" "Colonocytes: 198.7;Enterocytes: 212.6" "Cell type enhanced" "Detected in many" "Enterocytes: 212.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neutrophils: 11084213.3" "Tissue enriched" "Detected in single" 59 "liver: 5900.2" "HPA053785, HPA077297" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 18: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 22 "Nucleoplasm, Nucleoli fibrillar center" "Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA053785: , HPA077297: " "unprognostic (5.17e-2)" "unprognostic (1.18e-2)" "unprognostic (1.23e-2)" "unprognostic (2.12e-1)" "unprognostic (6.50e-2)" "unprognostic (7.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.99e-1)" "unprognostic (8.12e-2)" "unprognostic (7.13e-2)" "potential prognostic favorable (5.69e-6)" "unprognostic (2.09e-1)" "unprognostic (1.70e-3)" "unprognostic (5.76e-2)" "unprognostic (2.00e-1)" "unprognostic (1.95e-1)" "unprognostic (1.73e-2)" "unprognostic (1.72e-1)" "unprognostic (3.08e-1)" "unprognostic (2.49e-2)" "unprognostic (2.01e-1)" "unprognostic (2.03e-2)" "unprognostic (8.04e-2)" "unprognostic (3.10e-2)" "unprognostic (4.76e-2)" "unprognostic (4.49e-2)" "unprognostic (2.14e-1)" "unprognostic (2.78e-2)" "unprognostic (6.77e-2)" "unprognostic (1.16e-2)" "unprognostic (3.75e-1)" ESRRB "DFNB35, ERR2, ERRb, ERRbeta, ESRL2, NR3B2" ENSG00000119715 "Estrogen related receptor beta" O95718 14 76310712-76501837 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "kidney: 15.2;retina: 33.9" "Group enriched" "Detected in many" 5 "Distal convoluted tubule cells: 461.0;Loop of henle epithelial cells: 497.0;Myonuclei: 261.2;Retinal horizontal cells: 452.8;Rod photoreceptor cells: 838.4" "Group enriched" "Detected in many" 5 "Myocytes: 261.2;Neuronal cells: 838.4;Renal nephron cells: 497.0" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 23.6;choroid plexus epithelial cell: 61.0" "Cancer enriched" "Detected in single" 5 "Kidney Chromophobe (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.9" "Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Hepatocytes: 565717.6;Pancreas epithelial cells: 387251.7" "Tissue enhanced" "Detected in some" "intestine: 418213.3;pancreas: 626829.7" HPA074772 Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Retina - Visual perception" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 4 Nucleoplasm Cytosol "HPA074772: " "unprognostic (7.12e-2)" "unprognostic (1.07e-1)" ESRRG "ERR-gamma, ERRg, NR3B3" ENSG00000196482 "Estrogen related receptor gamma" P62508 1 216503246-217137755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 27.1;parathyroid gland: 43.5;retina: 33.5;stomach 1: 33.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 2711.2;Distal convoluted tubule cells: 6180.5;Loop of henle epithelial cells: 3812.1;Parietal cells: 1371.9;Renal collecting duct intercalated cells: 3411.9;Renal connecting tubule cells: 4138.3" "Cell type enhanced" "Detected in many" "Ductal cells: 4138.3;Glial cells: 2711.2;Renal nephron cells: 6180.5" "Cell type enhanced" "Detected in all" "Bergmann glia: 2637.2" "Cancer enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 18.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 14.7" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Eccrine sweat gland cells, Stomach - Parietal cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 650078.5;Distal tubules: 1523943.6;Large ducts: 2068782.7" "Tissue enriched" "Detected in single" 602 "salivary gland: 60150.6" HPA044678 Uncertain Approved Nucleoplasm No NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 25 Nucleoplasm "HPA044678: " "unprognostic (4.12e-2)" "unprognostic (2.01e-2)" "unprognostic (2.54e-2)" "unprognostic (4.38e-2)" "unprognostic (2.99e-1)" "unprognostic (1.05e-1)" "unprognostic (8.80e-2)" "potential prognostic favorable (7.11e-8)" "unprognostic (1.51e-2)" "unprognostic (5.77e-2)" "unprognostic (2.72e-2)" "unprognostic (6.85e-2)" "unprognostic (1.06e-1)" "unprognostic (7.35e-3)" "unprognostic (1.29e-1)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (3.61e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (5.35e-4)" "unprognostic (3.25e-1)" ETFA "EMA, GA2, MADD" ENSG00000140374 "Electron transfer flavoprotein subunit alpha" P13804 15 76188555-76311730 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 244.8;tongue: 244.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 523.5;Platelets: 913.4" "Cell type enhanced" "Detected in all" "Platelets: 913.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 443856836.4" "Tissue enhanced" "Detected in all" "heart muscle: 708566799.1" "HPA018990, HPA018993, HPA018996, HPA024089" Enhanced Enhanced Mitochondria NA NA 450000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 47: Platelets - Hemostasis" 33 Mitochondria "HPA018990: , HPA018993: , HPA018996: , HPA024089: " "unprognostic (4.41e-2)" "unprognostic (4.25e-3)" "unprognostic (8.69e-2)" "unprognostic (1.63e-1)" "unprognostic (3.15e-2)" "unprognostic (1.92e-2)" "unprognostic (6.89e-3)" "unprognostic (1.40e-2)" "unprognostic (3.59e-2)" "unprognostic (8.65e-3)" "potential prognostic favorable (4.97e-12)" "unprognostic (4.06e-3)" "unprognostic (4.40e-3)" "unprognostic (3.77e-2)" "unprognostic (7.86e-3)" "unprognostic (7.91e-2)" "unprognostic (1.83e-3)" "unprognostic (2.71e-2)" "unprognostic (2.75e-1)" "unprognostic (7.91e-2)" "unprognostic (1.29e-1)" "unprognostic (1.35e-3)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" "unprognostic (5.27e-2)" "unprognostic (5.07e-2)" "unprognostic (1.71e-1)" "unprognostic (2.65e-1)" "unprognostic (2.25e-2)" "unprognostic (8.06e-3)" "unprognostic (3.65e-1)" ETHE1 "HSCO, YF13H12" ENSG00000105755 "ETHE1 persulfide dioxygenase" O95571 19 43506719-43527230 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 239.8" "Cell type enhanced" "Detected in many" "Colonocytes: 1275.3;Enteric stem cells: 296.8;Enteric transient amplifying cells: 501.1;Enterocytes: 317.2;Esophageal apical cells: 1127.8;Goblet cells: 262.5" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 1127.8;Enterocytes: 1275.3;Proliferating cells: 501.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA028360, HPA029028, HPA029029" Enhanced Enhanced Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 17: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 Mitochondria "HPA028360: , HPA029028: , HPA029029: " "unprognostic (2.40e-1)" "unprognostic (1.21e-1)" "unprognostic (4.35e-2)" "unprognostic (8.60e-3)" "unprognostic (7.11e-2)" "unprognostic (1.69e-1)" "unprognostic (6.22e-2)" "unprognostic (2.07e-1)" "unprognostic (6.15e-2)" "unprognostic (7.44e-2)" "unprognostic (2.38e-2)" "unprognostic (2.17e-1)" "unprognostic (7.34e-3)" "unprognostic (2.47e-1)" "unprognostic (3.51e-2)" "unprognostic (1.13e-3)" "unprognostic (1.63e-2)" "unprognostic (2.27e-1)" "unprognostic (2.39e-2)" "unprognostic (3.04e-1)" "unprognostic (1.74e-1)" "unprognostic (2.97e-2)" "unprognostic (1.26e-2)" "unprognostic (2.16e-1)" "unprognostic (3.25e-1)" "unprognostic (4.31e-1)" "unprognostic (6.25e-2)" "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.44e-2)" "unprognostic (3.37e-1)" ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Foveolar cells: 671.1" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 671.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 597 "Distal tubules: 59307.6;Granulosa cells: 60050.8" "Group enriched" "Detected in some" 2491 "cerebral cortex: 124989.5;lymphoid tissue: 373209.3" "HPA010712, HPA029407" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 38: Non-specific - Transcription" "Cluster 68: Foveolar cells - Mucosal defense" 6 "Nucleoplasm, Plasma membrane, Cytosol" "HPA010712: , HPA029407: " "unprognostic (3.75e-1)" "unprognostic (1.37e-1)" "unprognostic (5.14e-2)" "unprognostic (3.06e-2)" "unprognostic (4.60e-3)" "unprognostic (5.61e-3)" "unprognostic (6.27e-2)" "unprognostic (7.60e-3)" "unprognostic (3.08e-2)" "unprognostic (6.74e-2)" "unprognostic (3.08e-2)" "unprognostic (7.94e-2)" "unprognostic (9.08e-2)" "unprognostic (3.50e-3)" "unprognostic (2.52e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (1.72e-2)" "unprognostic (3.24e-1)" "unprognostic (9.14e-3)" "unprognostic (1.96e-2)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (1.35e-1)" "unprognostic (1.03e-1)" "unprognostic (1.78e-2)" "unprognostic (1.23e-1)" "unprognostic (3.00e-1)" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (6.72e-2)" ETNPPL AGXT2L1 ENSG00000164089 "Ethanolamine-phosphate phospho-lyase" Q8TBG4 4 108742048-108763054 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 264.5;liver: 178.6" "Cell type enhanced" "Detected in some" "Astrocytes: 513.6;Bergmann glia: 175.7;Hepatocytes: 34.0;Parietal cells: 118.4;Salivary acinar cells: 40.2" "Cell type enriched" "Detected in many" 4 "Glial cells: 513.6" "Group enriched" "Detected in many" 25 "astrocyte: 542.6;Bergmann glia: 207.2" "Group enriched" "Detected in some" 21 "Glioblastoma Multiforme (TCGA): 18.2;Liver Hepatocellular Carcinoma (TCGA): 39.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 2057749.3;Hepatocytes: 5506852.2" "Group enriched" "Detected in some" 13193 "cerebral cortex: 1138430.1;liver: 1500134.1" "HPA044546, HPA072938" Enhanced Approved Nucleoplasm Yes NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Nucleoplasm "HPA044546: , HPA072938: " "unprognostic (5.74e-3)" "unprognostic (3.01e-3)" "unprognostic (9.00e-2)" "unprognostic (3.09e-3)" "unprognostic (1.16e-1)" "unprognostic (3.51e-1)" "unprognostic (2.14e-1)" ETS1 "ETS-1, EWSR2, FLJ10768" ENSG00000134954 "ETS proto-oncogene 1, transcription factor" P14921 11 128458761-128587558 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Immunity, Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 253.0" "Cell type enhanced" "Detected in many" "B-cells: 226.5;Innate lymphoid cells: 387.5;Lymphatic endothelial cells: 248.7;Melanocytes: 278.6;NK-cells: 688.7;T-cells: 738.6;Vascular endothelial cells: 390.9" "Cell type enhanced" "Detected in many" "NK-cells: 688.7;T-cells: 738.6" "Group enriched" "Detected in many" 5 "endothelial cell: 425.9;leukocyte: 767.2;pericyte: 441.8;vascular associated smooth muscle cell: 199.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 1702171.5" "Group enriched" "Detected in some" 7138 "intestine: 997514.7;lymphoid tissue: 430160.9" "CAB002575, HPA063230" Enhanced Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 24 Nucleoplasm "CAB002575: , HPA063230: " "potential prognostic favorable (3.91e-4)" "unprognostic (4.10e-2)" "unprognostic (1.61e-2)" "unprognostic (1.24e-1)" "unprognostic (3.45e-2)" "unprognostic (3.91e-2)" "unprognostic (2.57e-1)" "unprognostic (1.89e-1)" "unprognostic (3.66e-1)" "unprognostic (3.09e-1)" "validated prognostic favorable (2.39e-6)" "validated prognostic favorable (2.44e-4)" "unprognostic (2.84e-2)" "unprognostic (2.87e-2)" "unprognostic (4.38e-2)" "unprognostic (8.56e-2)" "unprognostic (9.10e-3)" "unprognostic (9.72e-2)" "unprognostic (2.15e-2)" "unprognostic (1.01e-1)" "unprognostic (3.26e-2)" "unprognostic (5.71e-2)" "potential prognostic unfavorable (8.96e-4)" "unprognostic (1.71e-1)" "unprognostic (2.57e-1)" "unprognostic (8.31e-2)" "unprognostic (4.23e-3)" "unprognostic (9.36e-2)" "unprognostic (3.37e-2)" "unprognostic (6.00e-2)" "unprognostic (6.66e-2)" ETV1 ER81 ENSG00000006468 "ETS variant transcription factor 1" P50549 7 13891229-13991425 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 124.0;salivary gland: 85.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 130.9;Alveolar cells type 2: 218.9;Bergmann glia: 106.6;Brain excitatory neurons: 256.6;Corticotrophs: 232.5;Neuroendocrine cells: 170.5;Oligodendrocyte progenitor cells: 260.0;Salivary acinar cells: 300.2" "Cell type enhanced" "Detected in many" "Acinar cells: 300.2;Alveolar cells: 218.9;Glial cells: 260.0;Neuronal cells: 256.6;Pituitary endocrine cells: 232.5" "Cell type enhanced" "Detected in all" "upper rhombic lip: 760.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 85.5" "Group enriched" "Detected in all" 4 "cerebellum: 235.6;thalamus: 74.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 72.9" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 284.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA068389, HPA077249" Supported Approved Nucleoplasm No No "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 12 Nucleoplasm "HPA068389: , HPA077249: " "unprognostic (2.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.10e-1)" "unprognostic (5.39e-3)" "unprognostic (2.94e-2)" "unprognostic (4.51e-2)" "unprognostic (9.17e-2)" "unprognostic (1.77e-2)" "unprognostic (7.45e-2)" "unprognostic (2.87e-2)" "unprognostic (3.57e-1)" "unprognostic (1.07e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (1.40e-6)" "unprognostic (9.11e-2)" "unprognostic (1.75e-2)" "unprognostic (3.51e-2)" "unprognostic (2.25e-1)" "unprognostic (3.06e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (1.13e-6)" "unprognostic (3.50e-1)" "unprognostic (2.95e-1)" "unprognostic (2.93e-1)" "unprognostic (2.65e-2)" "unprognostic (2.91e-2)" "unprognostic (1.67e-1)" "unprognostic (4.85e-3)" "unprognostic (2.60e-1)" "unprognostic (7.98e-2)" "unprognostic (2.73e-1)" ETV3 PE-1 ENSG00000117036 "ETS variant transcription factor 3" P41162 1 157121191-157138474 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 325.2;Epididymal basal cells: 132.4;monocytes: 127.9;Ocular epithelial cells: 162.4;pDCs: 147.0;Urothelial cells: 157.3" "Cell type enhanced" "Detected in many" "dendritic cells: 325.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 875 "Collecting ducts: 87516.7" "Tissue enriched" "Detected in single" 52 "lymphoid tissue: 5212.9" "HPA004794, HPA072144, HPA073211" Supported Approved Nucleoplasm,Nucleoli,Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 58: Skin - Keratinization" "Cluster 7: Non-specific - Ribosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 82: Dendritic cells - Antigen presentation" 25 Nucleoplasm "Nucleoli, Vesicles, Cytosol" "HPA004794: , HPA072144: , HPA073211: " "potential prognostic favorable (5.74e-4)" "unprognostic (1.63e-1)" "unprognostic (4.14e-1)" "unprognostic (5.84e-2)" "unprognostic (2.38e-2)" "unprognostic (3.58e-1)" "unprognostic (2.38e-1)" "unprognostic (2.14e-1)" "unprognostic (7.04e-2)" "unprognostic (2.28e-2)" "potential prognostic favorable (1.89e-5)" "unprognostic (3.26e-3)" "unprognostic (8.08e-3)" "unprognostic (1.20e-2)" "unprognostic (1.68e-1)" "unprognostic (4.44e-2)" "unprognostic (3.54e-2)" "unprognostic (1.40e-1)" "unprognostic (6.87e-2)" "unprognostic (3.99e-3)" "unprognostic (1.80e-2)" "unprognostic (1.85e-3)" "unprognostic (1.55e-1)" "unprognostic (1.58e-1)" "unprognostic (3.84e-3)" "unprognostic (1.87e-1)" "unprognostic (8.95e-2)" "unprognostic (3.94e-1)" "unprognostic (9.18e-2)" "unprognostic (6.82e-3)" "unprognostic (1.61e-1)" ETV4 "E1A-F, E1AF, PEA3" ENSG00000175832 "ETS variant transcription factor 4" P43268 17 43527844-43579620 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 33.4;Extravillous trophoblasts: 30.7;Gastric progenitor cells: 26.9;Pituitary stem cells: 36.7;Syncytiotrophoblasts: 23.4;Tuft cells: 69.2" "Cell type enhanced" "Detected in many" "Secretory gland support: 69.2;Stem cells: 36.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 202.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Colon - Enteric glia cells, Liver - Cholangiocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA005768 Approved Supported "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 82: Salivary gland - Secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 7 "Nucleoli rim" "Mitotic chromosome" "HPA005768: " "potential prognostic unfavorable (4.30e-4)" "unprognostic (1.46e-1)" "unprognostic (3.31e-1)" "unprognostic (1.20e-2)" "unprognostic (1.63e-1)" "unprognostic (4.74e-2)" "unprognostic (3.35e-2)" "potential prognostic unfavorable (9.92e-4)" "unprognostic (2.73e-3)" "unprognostic (2.47e-1)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (7.48e-5)" "unprognostic (4.49e-3)" "unprognostic (6.11e-2)" "unprognostic (1.45e-1)" "unprognostic (1.53e-1)" "unprognostic (3.69e-2)" "unprognostic (1.82e-1)" "unprognostic (4.17e-1)" "unprognostic (9.37e-2)" "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.96e-2)" "unprognostic (3.24e-1)" "unprognostic (2.15e-1)" "unprognostic (2.84e-1)" "unprognostic (1.69e-1)" "unprognostic (3.88e-2)" "unprognostic (4.45e-2)" EVC "DWF-1, EVC1" ENSG00000072840 "EvC ciliary complex subunit 1" P57679 4 5711201-5814305 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 71.4;Fibro-adipogenic progenitors: 73.0;Loop of henle epithelial cells: 216.8;Myosatellite cells: 97.2;Proximal tubule cells: 162.8;Renal collecting duct intercalated cells: 60.1" "Cell type enhanced" "Detected in many" "Renal nephron cells: 216.8;Stem cells: 97.2" "Cell type enhanced" "Detected in many" "astrocyte: 30.8;fibroblast: 41.7" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 52.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 37768 "Collecting ducts: 2490724.6;Glomeruli: 4760910.3;Macrophages: 4078721.3" "Tissue enriched" "Detected in single" 35872 "skeletal muscle: 3587215.4" "HPA008703, HPA016046" Uncertain Approved "Nucleoplasm,Primary cilium,Basal body,Cytosol" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" "Nucleoplasm, Basal body" "Primary cilium, Cytosol" "HPA008703: , HPA016046: " "unprognostic (4.70e-2)" "unprognostic (2.09e-1)" "unprognostic (2.10e-2)" "unprognostic (3.19e-3)" "unprognostic (5.50e-2)" "unprognostic (3.32e-1)" "unprognostic (4.70e-2)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (1.48e-1)" "unprognostic (3.41e-1)" "validated prognostic favorable (4.86e-9)" "validated prognostic favorable (9.99e-4)" "unprognostic (1.44e-3)" "unprognostic (6.16e-2)" "unprognostic (7.76e-2)" "unprognostic (3.22e-1)" "unprognostic (6.01e-3)" "unprognostic (7.47e-2)" "unprognostic (2.18e-1)" "unprognostic (1.01e-2)" "unprognostic (6.41e-3)" "unprognostic (5.22e-2)" "unprognostic (1.25e-1)" "unprognostic (3.99e-1)" "unprognostic (2.89e-1)" "unprognostic (1.13e-3)" "unprognostic (1.26e-1)" "unprognostic (4.79e-2)" "unprognostic (9.36e-2)" "unprognostic (1.19e-2)" "unprognostic (4.45e-1)" EVC2 LBN ENSG00000173040 "EvC ciliary complex subunit 2" Q86UK5 4 5542772-5709548 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ciliopathy, Disease variant, Dwarfism, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 109.6;Leydig cells: 56.6;Loop of henle epithelial cells: 58.1;Mesothelial cells: 56.9;Myosatellite cells: 61.3;Proximal tubule cells: 58.9;Renal collecting duct intercalated cells: 57.7" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 109.6" "Group enriched" "Detected in many" 4 "astrocyte: 30.2;Bergmann glia: 19.8;choroid plexus epithelial cell: 15.4;ependymal cell: 34.7;fibroblast: 57.2;pericyte: 22.7;vascular associated smooth muscle cell: 23.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 7213 "liver: 721299.9" "HPA040910, HPA048122" Uncertain Approved "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Basal body,Cytosol" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Plasma membrane, Microtubules, Cytokinetic bridge, Primary cilium" "Nucleoplasm, Primary cilium tip, Basal body, Cytosol" "HPA040910: , HPA048122: " "unprognostic (1.41e-1)" "unprognostic (8.81e-2)" "unprognostic (3.66e-1)" "unprognostic (4.30e-2)" "unprognostic (2.30e-2)" "unprognostic (8.63e-3)" "potential prognostic unfavorable (7.11e-6)" "unprognostic (2.85e-1)" "unprognostic (1.86e-2)" "potential prognostic favorable (6.40e-6)" "unprognostic (2.44e-2)" "unprognostic (5.64e-2)" "unprognostic (3.32e-2)" "unprognostic (1.45e-2)" "unprognostic (3.59e-2)" "unprognostic (1.16e-1)" "unprognostic (1.38e-1)" "unprognostic (3.88e-2)" "unprognostic (1.93e-1)" "unprognostic (3.09e-2)" "unprognostic (1.50e-1)" "unprognostic (1.19e-1)" "unprognostic (2.87e-2)" "unprognostic (1.87e-1)" "unprognostic (1.43e-1)" "unprognostic (1.35e-1)" "unprognostic (9.91e-2)" EVI2A "EVDA, EVI2" ENSG00000126860 "Ecotropic viral integration site 2A" P22794 17 31316410-31321749 "Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 164.5;lymphoid tissue: 97.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.3;cDC: 15.9;Epicardial cells: 22.7;Innate lymphoid cells: 18.8;Kupffer cells: 18.4;Macrophages: 18.0;Mast cells: 17.8;Microglia: 19.4;Monocyte progenitors: 17.0;monocytes: 24.6;Neutrophils: 68.7;NK-cells: 26.1;Oligodendrocytes: 74.3;Plasma cells: 23.7;T-cells: 27.0" "Cell type enhanced" "Detected in many" "Glial cells: 74.3;Myocytes: 45.3;Neutrophils: 68.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 24.2;oligodendrocyte: 95.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 35.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 30.0;Myeloma: 68.8" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA045033 Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 8 "Golgi apparatus, Vesicles, Plasma membrane, Primary cilium" "Primary cilium transition zone, Cytosol" "HPA045033: " "unprognostic (3.34e-1)" "unprognostic (1.21e-1)" "unprognostic (2.23e-1)" "unprognostic (1.44e-2)" "unprognostic (1.29e-1)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" "unprognostic (1.87e-1)" "unprognostic (6.70e-2)" "unprognostic (2.86e-1)" "unprognostic (4.76e-2)" "unprognostic (1.82e-1)" "unprognostic (2.34e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-2)" "unprognostic (8.55e-2)" "unprognostic (1.94e-2)" "unprognostic (1.54e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-2)" "unprognostic (7.14e-2)" "unprognostic (9.03e-2)" "unprognostic (2.05e-2)" "unprognostic (7.12e-2)" "unprognostic (2.06e-1)" "unprognostic (1.89e-3)" "unprognostic (6.39e-2)" "unprognostic (3.45e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" EXOC6 "DKFZp761I2124, EXOC6A, FLJ1125, MGC33397, Sec15, SEC15L, SEC15L1" ENSG00000138190 "Exocyst complex component 6" Q8TAG9 10 92826831-93059493 "Plasma proteins, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 152.0" "Cell type enhanced" "Detected in all" "Myonuclei: 1054.9;Neutrophil progenitors: 592.8;Neutrophils: 876.3;Rod photoreceptor cells: 469.7;Sertoli cells: 630.7" "Cell type enhanced" "Detected in all" "Myocytes: 1054.9;Neutrophils: 876.3;Reproductive supporting cells: 630.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 30.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "cerebral cortex: 1967709.8;lymphoid tissue: 2224407.1" HPA036285 Approved Uncertain "Centrosome,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 37 "Centrosome, Basal body, Cytosol" "HPA036285: " "unprognostic (1.47e-2)" "unprognostic (3.94e-2)" "unprognostic (3.90e-2)" "unprognostic (1.92e-1)" "unprognostic (1.05e-2)" "unprognostic (1.21e-1)" "unprognostic (9.67e-2)" "potential prognostic favorable (2.09e-4)" "unprognostic (6.84e-2)" "unprognostic (2.50e-2)" "potential prognostic favorable (8.64e-6)" "unprognostic (3.48e-2)" "unprognostic (3.14e-1)" "unprognostic (6.86e-2)" "unprognostic (3.66e-3)" "unprognostic (1.20e-1)" "unprognostic (7.22e-2)" "unprognostic (2.49e-1)" "unprognostic (2.81e-1)" "unprognostic (5.04e-2)" "unprognostic (1.53e-3)" "unprognostic (2.90e-2)" "unprognostic (2.50e-1)" "unprognostic (3.57e-2)" "unprognostic (1.43e-1)" "unprognostic (1.25e-1)" "unprognostic (3.42e-1)" "unprognostic (5.27e-2)" "unprognostic (8.93e-2)" "unprognostic (3.27e-1)" "unprognostic (2.14e-1)" EXOSC10 "p2, p3, p4, PM-Scl, PM/Scl-100, PMSCL2, RRP6, Rrp6p" ENSG00000171824 "Exosome component 10" Q01780 1 11066618-11099869 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay, rRNA processing" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 8219097.4;liver: 8423623.5" "HPA028470, HPA028484, CAB037141" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 67 "Nucleoli, Nucleoli rim" "Nucleoplasm, Cytosol" "CAB037141: , HPA028470: , HPA028484: " "unprognostic (2.89e-1)" "unprognostic (1.17e-1)" "unprognostic (6.31e-2)" "unprognostic (8.53e-3)" "unprognostic (3.98e-3)" "unprognostic (1.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.59e-2)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (8.51e-4)" "potential prognostic favorable (2.25e-5)" "unprognostic (2.15e-3)" "unprognostic (1.01e-1)" "validated prognostic unfavorable (4.83e-7)" "validated prognostic unfavorable (8.53e-4)" "unprognostic (5.79e-2)" "unprognostic (3.94e-2)" "unprognostic (3.14e-1)" "unprognostic (1.79e-1)" "unprognostic (1.41e-1)" "unprognostic (1.36e-1)" "unprognostic (2.04e-2)" "unprognostic (2.34e-2)" "unprognostic (8.27e-2)" "unprognostic (2.78e-2)" "unprognostic (2.93e-3)" "unprognostic (1.34e-1)" "unprognostic (2.68e-1)" "unprognostic (1.32e-1)" "unprognostic (5.75e-2)" "unprognostic (4.41e-2)" EXOSC2 "hRrp4p, p7, RRP4, Rrp4p" ENSG00000130713 "Exosome component 2" Q13868 9 130693721-130707288 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Deafness, Disease variant, Dwarfism, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 42.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12764564.7" "HPA021756, HPA021790" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 71 "Nucleoplasm, Nucleoli" "HPA021756: , HPA021790: " "unprognostic (5.51e-3)" "unprognostic (1.43e-2)" "unprognostic (1.30e-1)" "unprognostic (2.29e-1)" "unprognostic (2.04e-1)" "unprognostic (1.44e-2)" "unprognostic (9.52e-2)" "unprognostic (2.13e-3)" "unprognostic (1.74e-3)" "unprognostic (6.96e-3)" "potential prognostic favorable (4.74e-7)" "unprognostic (1.63e-3)" "unprognostic (9.46e-2)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (2.35e-3)" "potential prognostic unfavorable (3.50e-5)" "unprognostic (1.46e-3)" "unprognostic (2.37e-1)" "unprognostic (4.68e-3)" "unprognostic (3.44e-2)" "unprognostic (1.02e-1)" "unprognostic (1.99e-2)" "unprognostic (2.99e-2)" "unprognostic (1.28e-2)" "unprognostic (5.42e-2)" "unprognostic (1.05e-1)" "unprognostic (5.46e-2)" "unprognostic (5.93e-2)" "unprognostic (2.79e-1)" "unprognostic (7.75e-2)" "unprognostic (2.07e-1)" EXOSC8 "bA421P11.3, CIP3, EAP2, OIP2, p9, RRP43, Rrp43p" ENSG00000120699 "Exosome component 8" Q96B26 13 36998816-37025881 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "rRNA processing" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 265.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 265.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 10067868.2" "Tissue enhanced" "Detected in many" "intestine: 7895131.8" "CAB034240, HPA039702, HPA043942, HPA075230" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Mitotic chromosome,Vesicles,Cytosol" Yes NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 96 "Nucleoli fibrillar center, Mitotic chromosome" "Nucleoplasm, Vesicles, Cytosol" "CAB034240: , HPA039702: , HPA043942: , HPA075230: " "potential prognostic unfavorable (3.42e-4)" "unprognostic (1.91e-1)" "unprognostic (2.18e-1)" "unprognostic (1.12e-2)" "unprognostic (8.56e-2)" "unprognostic (1.97e-2)" "unprognostic (4.49e-2)" "unprognostic (2.35e-2)" "unprognostic (5.15e-3)" "unprognostic (7.98e-3)" "unprognostic (1.40e-1)" "unprognostic (2.22e-1)" "unprognostic (8.86e-3)" "unprognostic (1.55e-2)" "unprognostic (1.05e-2)" "unprognostic (4.88e-3)" "unprognostic (1.05e-2)" "unprognostic (1.41e-1)" "unprognostic (2.04e-1)" "unprognostic (1.05e-1)" "unprognostic (6.40e-2)" "unprognostic (4.65e-2)" "potential prognostic unfavorable (7.16e-5)" "unprognostic (1.76e-1)" "unprognostic (1.32e-1)" "unprognostic (2.47e-1)" "unprognostic (6.37e-3)" "unprognostic (6.52e-3)" "unprognostic (2.24e-1)" "unprognostic (1.88e-1)" "unprognostic (7.09e-3)" EYA1 BOR ENSG00000104313 "EYA transcriptional coactivator and phosphatase 1" Q99502 8 71197433-71592025 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 14.3;parathyroid gland: 22.3;prostate: 11.3" "Cell type enhanced" "Detected in many" "Astrocytes: 330.2;Choroid plexus epithelial cells: 651.8;Corticotrophs: 652.3;Ependymal cells: 559.7;Gonadotrophs: 1089.0;Medullary thymic epithelial cells: 1041.7;Pituitary stem cells: 2528.5;Respiratory basal cells: 443.7;Respiratory ciliated cells: 443.2;Respiratory secretory cells: 384.5;Somatotrophs: 337.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 651.8;Pituitary endocrine cells: 1089.0;Secretory gland support: 1041.7;Stem cells: 2528.5" "Group enriched" "Detected in many" 5 "astrocyte: 360.1;choroid plexus epithelial cell: 539.4;ependymal cell: 580.1;fibroblast: 360.1;medium spiny neuron: 208.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 20.9" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 26.6" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 3090 "heart muscle: 309044.1" HPA028917 Supported "Nucleoplasm,Nuclear bodies,Vesicles,Primary cilium" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 9 "Nucleoplasm, Nuclear bodies" "Vesicles, Primary cilium" "HPA028917: " "unprognostic (1.54e-2)" "unprognostic (2.08e-1)" "unprognostic (3.48e-2)" "potential prognostic favorable (9.69e-5)" "unprognostic (3.98e-1)" "unprognostic (1.95e-2)" "unprognostic (2.27e-1)" "unprognostic (1.76e-1)" "unprognostic (9.43e-2)" "unprognostic (1.31e-1)" "unprognostic (2.48e-1)" "unprognostic (5.69e-2)" "unprognostic (1.11e-1)" EYA2 EAB1 ENSG00000064655 "EYA transcriptional coactivator and phosphatase 2" O00167 20 46894624-47188844 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 52.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 546.5;Conjunctival goblet cells: 419.4;Endometrial glandular cells: 482.8;Prostatic hillock cells: 649.3;Respiratory basal cells: 780.6;Respiratory ionocytes: 497.8;Respiratory secretory cells: 500.3;Salivary basal cells: 743.2;Salivary duct cells: 806.3;Salivary ionocytes: 759.2;Salivary myoepithelial cells: 470.7" "Cell type enhanced" "Detected in many" "Basal cells: 780.6;Ductal cells: 806.3;Ionocytes: 759.2" "Cell type enhanced" "Detected in all" "astrocyte: 352.0;eccentric medium spiny neuron: 217.0;fibroblast: 212.9" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 138.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 23.8" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 191066.8;Large ducts: 288172.2" "Tissue enriched" "Detected in single" 10397 "salivary gland: 1039666.4" "HPA027024, HPA059291" Uncertain Supported Cytosol NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 9 Cytosol "HPA027024: , HPA059291: " "unprognostic (2.62e-2)" "unprognostic (9.11e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (3.09e-1)" "unprognostic (3.10e-2)" "unprognostic (6.56e-3)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.12e-2)" "unprognostic (5.17e-3)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" "unprognostic (2.03e-1)" "unprognostic (3.50e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (8.60e-2)" "unprognostic (2.22e-1)" "unprognostic (2.81e-1)" "unprognostic (1.21e-1)" "unprognostic (7.38e-2)" "unprognostic (3.05e-1)" "unprognostic (2.31e-1)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (7.53e-5)" "unprognostic (2.58e-2)" EYA3 DKFZp686C132 ENSG00000158161 "EYA transcriptional coactivator and phosphatase 3" Q99504 1 27970344-28088637 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Renal connecting tubule cells: 493.8" "Cell type enhanced" "Detected in all" "Ductal cells: 493.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Collecting ducts: 2905596.9;Granulosa cells: 5490978.4;Keratinocytes: 1499115.3" "Low tissue specificity" "Detected in many" "HPA052432, HPA062889" Uncertain Enhanced Nucleoplasm,Centrosome Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 Nucleoplasm Centrosome "HPA052432: , HPA062889: " "unprognostic (7.65e-3)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (8.32e-2)" "unprognostic (6.55e-2)" "unprognostic (4.18e-1)" "unprognostic (2.03e-1)" "unprognostic (1.23e-2)" "unprognostic (1.92e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (4.23e-6)" "unprognostic (3.54e-3)" "unprognostic (3.00e-3)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (1.73e-3)" "unprognostic (1.74e-1)" "unprognostic (4.69e-2)" "unprognostic (3.13e-1)" "unprognostic (9.98e-2)" "unprognostic (3.14e-2)" "unprognostic (9.15e-2)" "unprognostic (6.22e-2)" "unprognostic (1.17e-2)" "unprognostic (5.78e-2)" "unprognostic (3.21e-2)" "unprognostic (5.57e-2)" "unprognostic (5.80e-2)" "unprognostic (1.41e-1)" "unprognostic (1.58e-1)" "unprognostic (4.80e-2)" "unprognostic (9.14e-3)" EYA4 "CMD1J, DFNA10" ENSG00000112319 "EYA transcriptional coactivator and phosphatase 4" O95677 6 133240514-133532128 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, Hydrolase, Protein phosphatase" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 29.0;tongue: 18.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 414.8;Cardiomyocytes: 429.9;Choroid plexus epithelial cells: 475.1;Corticotrophs: 320.8;Ependymal cells: 821.1;Medullary thymic epithelial cells: 523.2;Myonuclei: 1095.3;Pituitary stem cells: 1750.9;Renal collecting duct principal cells: 717.4;Respiratory basal cells: 277.6;Thymic myoid cells: 311.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 821.1;Ductal cells: 717.4;Myocytes: 1095.3;Stem cells: 1750.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 414.3;ependymal cell: 957.0;LAMP5-LHX6 and Chandelier: 676.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Collecting ducts: 1576679.0;Fallopian tube cells: 418814.4" "Tissue enriched" "Detected in single" 429 "fallopian tube: 42907.9" "HPA004805, HPA038771, HPA038772" Enhanced Approved Nucleoplasm No NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 3: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 10 Nucleoplasm "HPA004805: , HPA038771: , HPA038772: " "unprognostic (2.82e-1)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (3.13e-4)" "unprognostic (1.41e-2)" "unprognostic (7.22e-2)" "unprognostic (7.32e-2)" "unprognostic (2.51e-2)" "unprognostic (2.00e-1)" "unprognostic (7.67e-2)" "unprognostic (6.91e-2)" "unprognostic (6.95e-2)" EYS "bA166P24.2, bA307F22.3, bA74E24.1, C6orf178, C6orf179, C6orf180, dJ1018A4.2, dJ303F19.1, EGFL10, EGFL11, RP25, SPAM" ENSG00000188107 "Eyes shut homolog" Q5T1H1 6 63719980-65707226 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 37 "retina: 23.1" "Group enriched" "Detected in many" 12 "Cone photoreceptor cells: 6630.6;Rod photoreceptor cells: 4150.9" "Cell type enriched" "Detected in many" 15 "Neuronal cells: 6630.6" "Cell type enhanced" "Detected in all" "hippocampal CA4: 421.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA027103 Uncertain "Plasma membrane,Cytosol,Flagellar centriole" "Secreted in other tissues" Other NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 37: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol, Flagellar centriole" "HPA027103: " "unprognostic (1.23e-1)" "unprognostic (8.47e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (7.12e-3)" "unprognostic (3.39e-2)" "unprognostic (1.43e-1)" EZH2 "ENX-1, EZH1, KMT6, KMT6A" ENSG00000106462 "Enhancer of zeste 2 polycomb repressive complex 2 subunit" Q15910 7 148807257-148884321 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 23.9;lymphoid tissue: 34.1;testis: 24.5" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 263.2;Late primary spermatocytes: 222.2;Megakaryocyte progenitors: 167.3;Monocyte progenitors: 269.0;Neutrophil progenitors: 246.2;Respiratory deuterosomal cells: 180.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 7.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 1300187.5;Neutrophils: 633353.1" "Tissue enriched" "Detected in single" 2294 "cerebral cortex: 229414.1" "CAB009589, HPA029131" Enhanced Enhanced Nucleoplasm NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 39: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 275 Nucleoplasm "CAB009589: , HPA029131: " "unprognostic (2.39e-1)" "unprognostic (1.04e-1)" "unprognostic (3.10e-2)" "unprognostic (3.75e-3)" "unprognostic (2.57e-2)" "unprognostic (6.06e-2)" "unprognostic (1.57e-1)" "unprognostic (4.43e-2)" "unprognostic (2.72e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.21e-3)" "unprognostic (1.42e-2)" "potential prognostic unfavorable (5.10e-5)" "validated prognostic unfavorable (1.91e-7)" "validated prognostic unfavorable (2.43e-5)" "unprognostic (4.25e-3)" "unprognostic (2.68e-3)" "unprognostic (1.50e-2)" "unprognostic (8.93e-2)" "unprognostic (2.52e-3)" "unprognostic (8.84e-3)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (4.68e-2)" "unprognostic (1.01e-3)" "unprognostic (2.65e-1)" "unprognostic (3.64e-1)" "unprognostic (9.03e-3)" "unprognostic (1.06e-3)" "unprognostic (1.92e-1)" "unprognostic (1.39e-1)" "unprognostic (1.27e-2)" EZHIP "CATACOMB, CXorf67" ENSG00000187690 "EZH inhibitory protein" Q86X51 X 51406948-51408843 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.7;testis: 5.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Testicular Germ Cell Tumor (TCGA): 18.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 1.9;Brain cancer: 1.0" "Testis - Spermatogonia" "Group enriched" "Detected in some" 18270 "Neutrophils: 2398384.1;Oocytes: 1947257.2;T-cells: 1135262.0" "Tissue enriched" "Detected in single" 939 "lymphoid tissue: 93889.8" "HPA004003, HPA006128" Enhanced Enhanced Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 51: Myeloma - Immunoglobulins" 5 Nucleoplasm "HPA004003: , HPA006128: " "unprognostic (3.98e-2)" "unprognostic (9.25e-2)" "unprognostic (3.42e-2)" "unprognostic (5.54e-2)" EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 2059.1;Esophageal apical cells: 2062.0;Ocular epithelial cells: 3071.0;Syncytiotrophoblasts: 2089.8;Urothelial cells: 2184.8" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 3071.0" "Group enriched" "Detected in many" 4 "astrocyte: 190.9;choroid plexus epithelial cell: 490.9;ependymal cell: 300.3;leukocyte: 200.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glomeruli: 1305836114.3" "Low tissue specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Supported "Plasma membrane" NA NA 33000000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 124 "Plasma membrane" "CAB004035: , CAB047324: , CAB075739: , HPA021616: " "unprognostic (3.75e-1)" "unprognostic (2.88e-3)" "unprognostic (1.63e-1)" "unprognostic (2.90e-2)" "unprognostic (4.11e-2)" "unprognostic (2.76e-1)" "unprognostic (4.30e-2)" "unprognostic (2.82e-1)" "unprognostic (6.87e-3)" "unprognostic (8.98e-2)" "potential prognostic favorable (1.21e-10)" "unprognostic (1.02e-3)" "potential prognostic favorable (1.01e-4)" "unprognostic (9.77e-3)" "unprognostic (6.42e-2)" "unprognostic (5.78e-2)" "unprognostic (2.01e-1)" "unprognostic (2.92e-1)" "unprognostic (2.44e-1)" "unprognostic (4.17e-2)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (2.15e-3)" "unprognostic (1.57e-1)" "unprognostic (1.28e-2)" "unprognostic (5.45e-2)" "unprognostic (2.22e-1)" "unprognostic (1.54e-1)" "unprognostic (2.54e-1)" "unprognostic (2.79e-1)" "unprognostic (2.72e-1)" F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.6;stomach 1: 41.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 86.2;Colonocytes: 112.2;Endometrial glandular cells: 91.2;Enteric stem cells: 67.3;Enteric transient amplifying cells: 65.4;Enterocytes: 96.5;Epididymal efferent duct absorptive cells: 62.7;Foveolar cells: 141.7;Goblet cells: 69.1;Ocular epithelial cells: 104.3;Pancreatic duct cells: 77.6;Suprabasal keratinocytes: 121.8;Urothelial cells: 134.6" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 134.6;Enterocytes: 112.2;Gastric glandular cells: 141.7;Suprabasal cells: 121.8" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 5.4;choroid plexus epithelial cell: 6.0;ependymal cell: 5.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 18.1" "Immune cell enhanced" "Detected in many" "neutrophil: 42.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.2" "Cancer enhanced" "Detected in many" "Bile duct cancer: 184.1" "Colon - Colon enterocytes, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skin - Keratinocyte (other), Spleen - Macrophages, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 460 "Proximal tubules: 46026.4" "Not detected" "Not detected" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 100: Stratified epithelial cells - Barrier functions" 82 "Plasma membrane" "CAB012989: , HPA014091: " "unprognostic (9.10e-2)" "unprognostic (6.12e-2)" "unprognostic (1.33e-1)" "unprognostic (6.73e-2)" "unprognostic (1.90e-2)" "unprognostic (2.99e-2)" "unprognostic (1.73e-1)" "unprognostic (2.12e-1)" "unprognostic (1.15e-3)" "unprognostic (1.84e-1)" "potential prognostic favorable (8.10e-14)" "unprognostic (4.34e-3)" "unprognostic (4.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.98e-3)" "potential prognostic unfavorable (6.06e-5)" "unprognostic (1.19e-2)" "unprognostic (8.06e-2)" "unprognostic (5.80e-2)" "unprognostic (4.89e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-3)" "unprognostic (4.18e-1)" "unprognostic (2.14e-2)" "unprognostic (2.34e-2)" "unprognostic (1.16e-1)" "unprognostic (5.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.94e-1)" "unprognostic (9.19e-3)" "unprognostic (1.83e-1)" F3 "CD142, TF" ENSG00000117525 "Coagulation factor III, tissue factor" P13726 1 94529173-94541759 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Blood coagulation, Hemostasis" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 814.0;Alveolar cells type 2: 428.7;Conjunctival goblet cells: 927.2;Endometrial secretory cells: 544.8;Epididymal basal cells: 469.8;Müller glia: 426.2;Ocular epithelial cells: 1205.2;Pancreatic acinar cells: 965.0;Peritubular myoid cells: 763.1;Respiratory basal cells: 686.2;Respiratory deuterosomal cells: 869.7;Respiratory secretory cells: 950.2" "Cell type enhanced" "Detected in many" "Acinar cells: 965.0;Barrier epithelial cells: 1205.2;Ciliated cells: 869.7;Goblet cells: 927.2;Secretory cells: 950.2" "Cell type enhanced" "Detected in many" "astrocyte: 248.5;fibroblast: 443.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 655.6" "Kidney - Podocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 8228045.4;Glomeruli: 5602852.5;Microglia and Neuropil: 5211767.4" "Group enriched" "Detected in many" "cerebral cortex: 5166749.4;intestine: 9643792.6;Stomach: 2703208.5" "CAB009438, HPA049292, HPA069132" Uncertain Approved Vesicles "Secreted to blood" "Blood coagulation" NA NA 603000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 12 Vesicles "CAB009438: , HPA049292: , HPA069132: " "unprognostic (1.24e-1)" "unprognostic (5.40e-2)" "unprognostic (2.52e-1)" "unprognostic (2.73e-2)" "unprognostic (4.70e-2)" "unprognostic (1.35e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (7.75e-5)" "unprognostic (4.84e-3)" "unprognostic (1.44e-3)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (3.19e-2)" "unprognostic (1.61e-2)" "unprognostic (5.22e-2)" "unprognostic (4.06e-2)" "unprognostic (7.62e-2)" "unprognostic (1.06e-1)" "unprognostic (3.99e-1)" "unprognostic (1.71e-1)" "unprognostic (4.70e-2)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (2.62e-2)" "unprognostic (2.11e-1)" "unprognostic (6.14e-2)" "unprognostic (3.20e-2)" "unprognostic (3.77e-1)" "unprognostic (5.69e-2)" "unprognostic (1.18e-1)" "unprognostic (1.55e-1)" "unprognostic (8.97e-2)" FABP1 L-FABP ENSG00000163586 "Fatty acid binding protein 1" P07148 2 88122982-88128062 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 12 "intestine: 5139.5;liver: 12176.2" "Cell type enhanced" "Detected in some" "Colonocytes: 24611.3;Enteric transient amplifying cells: 5231.9;Enterocytes: 14089.0;Hepatocytes: 5907.7" "Cell type enriched" "Detected in many" 4 "Enterocytes: 24611.3" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Group enriched" "Detected in many" 13 "Colon Adenocarcinoma (TCGA): 1875.4;Liver Hepatocellular Carcinoma (TCGA): 3548.7;Rectum Adenocarcinoma (TCGA): 2030.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 408.0;colorectal cancer: 909.1;liver cancer: 309.9" "Colon - Colon enterocytes, Kidney - Proximal tubular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in all" "Hepatocytes: 1503753216.9" "Tissue enriched" "Detected in all" "liver: 4167857595.3" "CAB002305, HPA028275" Enhanced Approved Nucleoplasm,Cytosol NA NA 35000000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "Nucleoplasm, Cytosol" "CAB002305: , HPA028275: " "unprognostic (3.14e-1)" "potential prognostic favorable (9.93e-4)" "potential prognostic favorable (1.49e-5)" "unprognostic (7.38e-3)" "unprognostic (1.19e-1)" "unprognostic (2.28e-2)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (1.99e-2)" "unprognostic (2.50e-1)" "unprognostic (4.77e-2)" "unprognostic (3.06e-2)" "unprognostic (8.99e-1)" "unprognostic (5.37e-2)" "unprognostic (1.18e-1)" "unprognostic (4.96e-1)" FABP2 I-FABP ENSG00000145384 "Fatty acid binding protein 2" P12104 4 119317250-119322138 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 172 "intestine: 517.8" "Cell type enriched" "Detected in some" 12 "Enterocytes: 5633.9" "Cell type enriched" "Detected in some" 12 "Enterocytes: 5633.9" "Cell type enriched" "Detected in single" 22 "choroid plexus epithelial cell: 8.2" "Group enriched" "Detected in some" 8 "Colon Adenocarcinoma (TCGA): 5.5;Pancreatic Adenocarcinoma (TCGA): 2.6;Rectum Adenocarcinoma (TCGA): 4.6;Stomach Adenocarcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "basophil: 1.6;neutrophil: 4.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Group enriched" "Detected in some" 5 "Bile duct cancer: 2.0;colorectal cancer: 1.8;Gastric cancer: 1.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "intestine: 122819433.9" "HPA034607, CAB047325, CAB047326" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 710000 "Cluster 35: Neutrophils - Protein binding" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 2 "Actin filaments, Cytosol" "Plasma membrane" "CAB047325: , CAB047326: , HPA034607: " "unprognostic (5.26e-2)" "unprognostic (6.08e-2)" "unprognostic (3.15e-1)" "unprognostic (1.05e-1)" "unprognostic (5.42e-2)" "unprognostic (1.52e-3)" "unprognostic (1.29e-1)" FABP4 "A-FABP, aP2" ENSG00000170323 "Fatty acid binding protein 4" P15090 8 81478419-81483236 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "adipose tissue: 3555.6;breast: 2416.5" "Cell type enhanced" "Detected in many" "Adipocytes: 1143.4;Lymphatic endothelial cells: 944.3;Macrophages: 285.3;Pericytes: 1116.7;Urothelial cells: 1743.6;Vascular endothelial cells: 1669.2;Vascular smooth muscle cells: 342.0" "Group enriched" "Detected in many" 4 "Adipocytes: 1143.4;Barrier epithelial cells: 1743.6;Endothelial cells: 1669.2;Mural cells: 1116.7" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 21.2;pericyte: 6.8" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 50.2;Breast Invasive Carcinoma (TCGA): 46.3;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 90.0;Head and Neck Squamous Cell Carcinoma (TCGA): 75.5" "Region enriched" "Detected in some" 10 "choroid plexus: 71.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bladder cancer: 168.0;Rhabdoid: 56.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Endothelial cells, Minor Salivary Gland - Adipocytes (Minor salivary gland), Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 141121217.6;Neutrophils: 99785391.6" "Group enriched" "Detected in all" "bone marrow: 380325122.3;heart muscle: 439014376.7;intestine: 624889636.1;skin: 215886244.0" "HPA002188, CAB024961, CAB080201" Enhanced Approved Nucleoplasm,Cytosol NA NA 19000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 36: Choroid plexus - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 "Nucleoplasm, Cytosol" "CAB024961: , CAB080201: , HPA002188: " "unprognostic (1.24e-1)" "unprognostic (8.56e-2)" "unprognostic (7.61e-3)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (8.15e-3)" "unprognostic (1.68e-1)" "unprognostic (2.11e-1)" "unprognostic (3.15e-2)" "unprognostic (4.04e-3)" "unprognostic (1.66e-1)" "potential prognostic favorable (8.60e-5)" "unprognostic (3.44e-2)" "potential prognostic favorable (4.95e-4)" "unprognostic (3.97e-3)" "unprognostic (1.68e-1)" "unprognostic (1.33e-1)" "unprognostic (5.63e-3)" "unprognostic (2.29e-2)" "unprognostic (4.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (3.29e-1)" "unprognostic (3.90e-2)" "unprognostic (1.79e-2)" "unprognostic (1.55e-1)" "unprognostic (1.42e-3)" "unprognostic (9.99e-3)" "unprognostic (1.87e-1)" FABP7 "B-FABP, BLBP" ENSG00000164434 "Fatty acid binding protein 7" O15540 6 122779716-122784074 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Transport "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 232.2;retina: 162.4;tongue: 186.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 325.7;Müller glia: 895.8" "Group enriched" "Detected in some" 6 "Glial cells: 895.8;Trophoblast cells: 325.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 58.7;deep-layer near-projecting: 62.7" "Group enriched" "Detected in many" 10 "Glioblastoma Multiforme (TCGA): 894.0;Kidney Renal Clear Cell Carcinoma (TCGA): 510.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 41.3;Kidney cancer: 40.7;skin cancer: 60.5" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Region enriched" "Detected in all" 5 "olfactory bulb: 1195.5" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 64028939.7;Microglia and Neuropil: 30445189.2" "Group enriched" "Detected in many" "cerebral cortex: 134410007.0;intestine: 54718976.6" "CAB025488, HPA028825, CAB058697" Enhanced Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 11: Muller glia cells - Retinal homeostasis" 5 Nucleoplasm "Golgi apparatus, Cytosol" "CAB025488: , CAB058697: , HPA028825: " "unprognostic (1.73e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (3.92e-1)" "unprognostic (1.52e-1)" "unprognostic (7.27e-2)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (1.94e-2)" "unprognostic (7.43e-3)" "unprognostic (9.44e-2)" "potential prognostic unfavorable (7.16e-4)" "unprognostic (8.74e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (1.71e-1)" "unprognostic (4.34e-3)" "unprognostic (1.27e-1)" "unprognostic (2.55e-2)" "unprognostic (6.28e-2)" FADS2 "D6D, DES6, FADSD6, LLCDL2, SLL0262, TU13" ENSG00000134824 "Fatty acid desaturase 2" O95864 11 61792980-61867354 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Transport" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 302.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 164.1;Astrocytes: 145.0;Megakaryocyte progenitors: 150.3;Retinal ganglion cells: 115.9;Retinal pigment epithelial cells: 183.3" "Cell type enhanced" "Detected in many" "Pigment cells: 183.3" "Cell type enhanced" "Detected in all" "astrocyte: 188.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 280.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 4364290.6" "Group enriched" "Detected in many" "cerebral cortex: 1416465.9;lymphoid tissue: 839183.6;skin: 2728226.5" "HPA006741, HPA079284" Approved Approved "Nuclear membrane,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 2 "Endoplasmic reticulum" "Nuclear membrane, Plasma membrane" "HPA006741: , HPA079284: " "unprognostic (2.02e-2)" "unprognostic (1.73e-1)" "unprognostic (2.76e-2)" "unprognostic (1.29e-1)" "unprognostic (1.00e-1)" "unprognostic (2.22e-1)" "unprognostic (1.80e-1)" "unprognostic (1.66e-3)" "unprognostic (4.23e-2)" "unprognostic (9.39e-3)" "unprognostic (1.28e-1)" "unprognostic (4.61e-2)" "unprognostic (1.93e-2)" "unprognostic (4.54e-2)" "unprognostic (5.86e-3)" "unprognostic (5.10e-2)" "unprognostic (4.53e-2)" "unprognostic (8.81e-3)" "unprognostic (2.72e-1)" "unprognostic (4.30e-1)" "unprognostic (1.16e-1)" "unprognostic (2.99e-3)" "unprognostic (2.44e-2)" "unprognostic (1.28e-1)" "unprognostic (6.61e-2)" "unprognostic (1.08e-1)" "unprognostic (5.21e-3)" "unprognostic (6.84e-2)" "unprognostic (9.02e-2)" "unprognostic (9.43e-3)" "unprognostic (1.03e-1)" FAF1 "CGI-03, hFAF1, HFAF1s, UBXD12, UBXN3A" ENSG00000185104 "Fas associated factor 1" Q9UNN5 1 50437028-50960267 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA018253, CAB072814" Approved Enhanced "Nucleoplasm,Acrosome,Equatorial segment,Perinuclear theca" NA NA 22000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 79: Photoreceptor cells - Phototransduction" 77 Nucleoplasm "Acrosome, Equatorial segment, Perinuclear theca" "CAB072814: , HPA018253: " "unprognostic (4.93e-2)" "unprognostic (2.09e-1)" "unprognostic (1.94e-3)" "unprognostic (4.22e-2)" "unprognostic (1.44e-1)" "unprognostic (2.59e-2)" "unprognostic (8.40e-2)" "unprognostic (1.20e-2)" "unprognostic (2.75e-2)" "unprognostic (8.41e-3)" "unprognostic (1.31e-1)" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "validated prognostic unfavorable (1.52e-5)" "validated prognostic unfavorable (6.14e-6)" "unprognostic (6.38e-2)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (3.02e-1)" "unprognostic (1.34e-1)" "unprognostic (4.15e-2)" "unprognostic (4.57e-2)" "unprognostic (3.89e-1)" "unprognostic (9.73e-2)" "unprognostic (1.48e-1)" "unprognostic (1.27e-1)" "unprognostic (2.98e-1)" "unprognostic (1.36e-1)" "unprognostic (2.21e-1)" "unprognostic (3.01e-2)" "unprognostic (8.40e-2)" FAM110A "bA371L19.3, C20orf55" ENSG00000125898 "Family with sequence similarity 110 member A" Q9BQ89 20 833715-857463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 68.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 96.3;Esophageal basal cells: 59.5;Esophageal suprabasal cells: 75.5;Extravillous trophoblasts: 218.7;Megakaryocytes: 86.5;Migrating cytotrophoblasts: 58.3;Platelets: 260.0" "Cell type enhanced" "Detected in many" "Platelets: 260.0;Trophoblast cells: 218.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.3;leukocyte: 23.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 546.1;eosinophil: 163.7;intermediate monocyte: 160.5;non-classical monocyte: 249.3" "Group enriched" "Detected in all" 9 "granulocytes: 546.1;monocytes: 249.3" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Skin - Keratinocyte (granular), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 145 "Keratinocytes: 14450.5" "Not detected" "Not detected" "CAB034110, HPA069240" Uncertain Uncertain Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 44 "Nucleoplasm, Vesicles" Cytosol "CAB034110: , HPA069240: " "unprognostic (9.56e-2)" "unprognostic (6.43e-3)" "unprognostic (1.82e-2)" "unprognostic (2.98e-1)" "unprognostic (5.92e-2)" "unprognostic (1.61e-1)" "unprognostic (2.14e-1)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (6.44e-2)" "unprognostic (1.61e-1)" "unprognostic (6.44e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (2.67e-2)" "unprognostic (1.88e-1)" "unprognostic (2.56e-2)" "unprognostic (2.41e-3)" "unprognostic (6.73e-3)" "unprognostic (3.09e-2)" "unprognostic (2.46e-1)" "unprognostic (3.01e-2)" "unprognostic (6.35e-2)" "unprognostic (1.54e-1)" "unprognostic (7.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-2)" "unprognostic (2.39e-2)" "unprognostic (7.05e-2)" "unprognostic (1.12e-1)" FAM111B CANP ENSG00000189057 "FAM111 trypsin like peptidase B" Q6SJ93 11 59107185-59127412 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 16.7" "Cell type enriched" "Detected in many" 11 "Respiratory deuterosomal cells: 433.3" "Cell type enriched" "Detected in many" 11 "Ciliated cells: 433.3" "Cell type enhanced" "Detected in some" "leukocyte: 1.3;oligodendrocyte precursor cell: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 3.3;naive B-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 83 "salivary gland: 8337.2" HPA038637 Uncertain Approved Nucleoplasm,Cytosol No Yes "Cluster 14: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 Nucleoplasm Cytosol "HPA038637: " "unprognostic (1.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.40e-2)" "unprognostic (8.60e-2)" "unprognostic (1.29e-1)" "unprognostic (6.36e-2)" "unprognostic (4.04e-1)" "unprognostic (4.14e-2)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (5.94e-2)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (7.34e-6)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (5.96e-3)" "potential prognostic unfavorable (1.29e-6)" "unprognostic (1.20e-3)" "unprognostic (2.43e-1)" "unprognostic (6.96e-2)" "unprognostic (4.11e-2)" "unprognostic (4.56e-2)" "potential prognostic unfavorable (6.45e-5)" "unprognostic (1.00e-1)" "unprognostic (6.79e-3)" "unprognostic (1.48e-3)" "unprognostic (2.42e-1)" "unprognostic (1.42e-1)" "unprognostic (4.46e-2)" "unprognostic (1.43e-1)" "potential prognostic favorable (3.69e-4)" "unprognostic (2.42e-2)" FAM114A1 Noxp20 ENSG00000197712 "Family with sequence similarity 114 member A1" Q8IWE2 4 38867677-38945739 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 264.5;Lacrimal acinar cells: 345.1;Salivary acinar cells: 221.7;Salivary ionocytes: 270.7" "Cell type enhanced" "Detected in all" "Acinar cells: 345.1" "Cell type enhanced" "Detected in many" "fibroblast: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 3.2;intermediate monocyte: 3.6;myeloid DC: 2.6;neutrophil: 2.4;non-classical monocyte: 1.4" "Group enriched" "Detected in many" 7 "dendritic cells: 2.6;granulocytes: 2.4;monocytes: 3.6" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Hepatocytes, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 9463210.7" "Low tissue specificity" "Detected in all" "HPA067948, HPA069104, HPA069701" Uncertain Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 13000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 "Golgi apparatus, Cytosol" Nucleoplasm "HPA067948: , HPA069104: , HPA069701: " "unprognostic (2.14e-2)" "unprognostic (9.94e-3)" "unprognostic (3.91e-1)" "unprognostic (5.95e-3)" "unprognostic (5.46e-2)" "unprognostic (1.66e-2)" "unprognostic (4.04e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (9.03e-2)" "unprognostic (1.31e-2)" "potential prognostic favorable (4.11e-4)" "unprognostic (2.79e-1)" "unprognostic (5.52e-3)" "unprognostic (1.68e-1)" "unprognostic (9.44e-2)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (5.67e-4)" "unprognostic (5.93e-2)" "unprognostic (1.43e-1)" "unprognostic (3.00e-1)" "unprognostic (3.80e-2)" "unprognostic (5.56e-2)" "unprognostic (1.56e-1)" "unprognostic (2.44e-1)" "unprognostic (5.77e-2)" "unprognostic (2.31e-1)" "unprognostic (5.43e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-2)" "unprognostic (1.23e-1)" FAM117B "ALS2CR13, FLJ38771" ENSG00000138439 "Family with sequence similarity 117 member B" Q6P1L5 2 202634969-202769757 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 200.1;Prostatic glandular cells: 202.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 4557139.2;Oocytes: 6459999.9" "Tissue enhanced" "Detected in many" "cerebral cortex: 192811.6" "HPA003229, HPA028746" Uncertain Approved Nucleoplasm,Centrosome Yes No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 43 Nucleoplasm Centrosome "HPA003229: , HPA028746: " "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (1.24e-1)" "unprognostic (8.51e-2)" "unprognostic (2.34e-1)" "unprognostic (2.31e-2)" "unprognostic (1.21e-1)" "unprognostic (1.02e-3)" "unprognostic (2.59e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (6.88e-5)" "unprognostic (1.78e-2)" "unprognostic (1.35e-1)" "unprognostic (1.70e-2)" "unprognostic (2.62e-2)" "unprognostic (2.61e-1)" "unprognostic (7.11e-2)" "unprognostic (3.40e-2)" "potential prognostic favorable (5.30e-5)" "unprognostic (7.73e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-2)" "unprognostic (1.17e-2)" "unprognostic (4.07e-1)" "unprognostic (3.75e-3)" "unprognostic (1.96e-1)" "unprognostic (7.97e-2)" "unprognostic (2.15e-1)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (2.73e-1)" FAM131A "C3orf40, MGC21688" ENSG00000175182 "Family with sequence similarity 131 member A" Q6UXB0 3 184335926-184348421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 96.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 63.8;Lactotrophs: 85.7;Somatotrophs: 60.9;Syncytiotrophoblasts: 54.9" "Cell type enhanced" "Detected in many" "Pituitary endocrine cells: 85.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 350302.5" "Tissue enriched" "Detected in single" 30 "cerebral cortex: 2978.9" HPA042800 Uncertain Approved "Nucleoli rim,Mitotic chromosome" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nucleoli rim" "Mitotic chromosome" "HPA042800: " "unprognostic (1.29e-1)" "unprognostic (9.27e-2)" "unprognostic (1.93e-1)" "unprognostic (2.52e-2)" "unprognostic (2.00e-2)" "unprognostic (2.98e-1)" "unprognostic (1.27e-1)" "unprognostic (5.01e-2)" "unprognostic (1.21e-1)" "unprognostic (1.74e-2)" "unprognostic (1.64e-1)" "unprognostic (4.67e-2)" "unprognostic (3.89e-3)" "unprognostic (4.50e-3)" "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (7.77e-2)" "unprognostic (4.24e-2)" "potential prognostic favorable (5.85e-4)" "unprognostic (6.73e-2)" "unprognostic (6.33e-2)" "unprognostic (2.11e-1)" "unprognostic (5.01e-2)" "unprognostic (1.02e-2)" "unprognostic (1.83e-2)" "unprognostic (1.03e-1)" "unprognostic (1.08e-2)" "unprognostic (9.44e-3)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (8.07e-2)" FAM133A "CT115, FLJ37659, RP1-32F7.2" ENSG00000179083 "Family with sequence similarity 133 member A" Q8N9E0 X 93674013-93712274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9;testis: 7.3" "Cell type enriched" "Detected in some" 8 "Sertoli cells: 385.6" "Cell type enriched" "Detected in many" 8 "Reproductive supporting cells: 385.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Gallbladder cancer: 27.2;Myeloma: 13.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA066175, HPA069513" Approved Nucleoplasm,Nucleoli NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 58 Nucleoli Nucleoplasm "HPA066175: , HPA069513: " "unprognostic (1.64e-2)" "potential prognostic favorable (6.87e-4)" "unprognostic (2.22e-3)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (3.81e-2)" "unprognostic (1.10e-1)" "unprognostic (3.63e-2)" "unprognostic (8.76e-2)" "unprognostic (1.16e-1)" "unprognostic (2.93e-1)" FAM133B MGC40405 ENSG00000234545 "Family with sequence similarity 133 member B" Q5BKY9 7 92560758-92590393 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 8922 "Granulosa cells: 892246.4" "Tissue enriched" "Detected in single" 3717 "lymphoid tissue: 371725.6" "HPA066175, HPA069513" Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" Nucleoli Nucleoplasm "HPA066175: , HPA069513: " "unprognostic (1.01e-3)" "unprognostic (1.30e-1)" "unprognostic (6.70e-2)" "unprognostic (5.99e-2)" "unprognostic (1.64e-1)" "unprognostic (1.07e-1)" "unprognostic (2.17e-1)" "potential prognostic favorable (3.44e-4)" "unprognostic (3.63e-1)" "unprognostic (3.78e-2)" "unprognostic (5.87e-3)" "unprognostic (1.06e-1)" "unprognostic (2.15e-1)" "unprognostic (3.53e-2)" "unprognostic (4.53e-2)" "unprognostic (2.11e-1)" "unprognostic (6.42e-2)" "unprognostic (1.29e-2)" "unprognostic (1.13e-1)" "unprognostic (1.19e-1)" "unprognostic (5.54e-2)" "unprognostic (1.14e-1)" "unprognostic (1.13e-2)" "unprognostic (1.88e-1)" "unprognostic (9.23e-2)" "unprognostic (6.56e-2)" "unprognostic (1.88e-2)" "unprognostic (1.10e-1)" "unprognostic (4.55e-1)" "unprognostic (3.24e-1)" "unprognostic (2.87e-1)" FAM149B1 KIAA0974 ENSG00000138286 "Family with sequence similarity 149 member B1" Q96BN6 10 73168119-73244504 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039189, HPA039859" Uncertain Approved "Microtubules,Primary cilium,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Microtubules, Primary cilium" Cytosol "HPA039189: , HPA039859: " "unprognostic (1.10e-1)" "unprognostic (2.50e-2)" "unprognostic (1.55e-1)" "unprognostic (6.32e-2)" "unprognostic (1.40e-1)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "potential prognostic favorable (8.82e-5)" "unprognostic (4.73e-2)" "unprognostic (4.35e-2)" "potential prognostic favorable (2.91e-7)" "unprognostic (5.42e-3)" "unprognostic (4.27e-2)" "unprognostic (2.11e-1)" "unprognostic (1.81e-1)" "unprognostic (2.70e-1)" "unprognostic (4.09e-2)" "unprognostic (4.77e-2)" "unprognostic (6.28e-2)" "unprognostic (5.36e-2)" "unprognostic (3.51e-2)" "unprognostic (6.52e-3)" "unprognostic (7.37e-2)" "unprognostic (6.28e-2)" "unprognostic (8.23e-2)" "unprognostic (1.21e-1)" "unprognostic (2.87e-2)" "unprognostic (1.71e-1)" "unprognostic (2.21e-1)" "unprognostic (8.60e-2)" "unprognostic (7.93e-2)" FAM161A "FLJ13305, RP28" ENSG00000170264 "FAM161 centrosomal protein A" Q3B820 2 61824848-61854143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Sensory transduction, Vision" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "retina: 26.9" "Cell type enhanced" "Detected in many" "Early spermatids: 157.4;Late primary spermatocytes: 168.2;Late spermatids: 474.9;Respiratory ciliated cells: 107.6;Retinal pigment epithelial cells: 162.0;Rod photoreceptor cells: 395.5" "Cell type enhanced" "Detected in many" "Neuronal cells: 395.5;Pigment cells: 162.0;Spermatogenic cell types: 474.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 2296135.4;Oocytes: 1575389.8" "Tissue enriched" "Detected in single" 242 "fallopian tube: 24247.5" "HPA032119, HPA064830" Approved Supported "Nucleoplasm,Golgi apparatus,Centrosome,Basal body,Cytosol,Flagellar centriole" NA Yes "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 79: Photoreceptor cells - Phototransduction" 125 "Centrosome, Basal body, Flagellar centriole" "Nucleoplasm, Golgi apparatus, Cytosol" "HPA032119: , HPA064830: " "unprognostic (5.14e-2)" "unprognostic (2.67e-1)" "unprognostic (6.35e-2)" "unprognostic (1.02e-1)" "unprognostic (7.75e-2)" "unprognostic (2.74e-1)" "potential prognostic favorable (9.19e-7)" "unprognostic (4.63e-2)" "unprognostic (4.72e-3)" "unprognostic (2.69e-1)" "unprognostic (2.24e-1)" "unprognostic (1.91e-1)" "unprognostic (3.96e-3)" "unprognostic (3.61e-2)" "unprognostic (2.05e-1)" "unprognostic (2.26e-2)" "unprognostic (2.23e-1)" "unprognostic (3.48e-1)" "unprognostic (6.85e-3)" "unprognostic (2.65e-1)" FAM161B "C14orf44, FLJ31697" ENSG00000156050 "FAM161 centrosomal protein B" Q96MY7 14 73931501-73950414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 35.3;Early spermatids: 85.7;Late spermatids: 195.4;Retinal ganglion cells: 34.8;Rod photoreceptor cells: 31.6" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 195.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 35.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bile duct cancer: 19.9" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 28303 "Fallopian tube cells: 2830309.3" "Tissue enriched" "Detected in single" 27498 "fallopian tube: 2749838.3" HPA019125 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Ovary - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 65: Non-specific - Cell growth & division" 54 "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA019125: " "unprognostic (1.98e-1)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (2.48e-2)" "unprognostic (7.66e-3)" "unprognostic (2.87e-1)" "unprognostic (1.22e-1)" "unprognostic (3.03e-1)" "unprognostic (2.73e-3)" "unprognostic (1.22e-2)" "unprognostic (3.34e-2)" "unprognostic (6.00e-3)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (6.09e-3)" "unprognostic (4.48e-2)" "unprognostic (1.13e-1)" "unprognostic (5.45e-2)" "unprognostic (3.29e-2)" "unprognostic (1.32e-1)" "unprognostic (1.91e-2)" "unprognostic (9.64e-2)" "unprognostic (3.67e-1)" "unprognostic (1.55e-1)" "unprognostic (2.90e-2)" "unprognostic (6.00e-2)" "unprognostic (9.77e-2)" "unprognostic (5.95e-2)" "unprognostic (4.56e-2)" "unprognostic (1.17e-3)" "unprognostic (3.18e-2)" FAM167B "C1orf90, DIORA-2, MGC10820" ENSG00000183615 "Family with sequence similarity 167 member B" Q9BTA0 1 32247222-32248856 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 44.4" "Cell type enriched" "Detected in some" 4 "Vascular endothelial cells: 92.5" "Cell type enriched" "Detected in many" 4 "Endothelial cells: 92.5" "Group enriched" "Detected in some" 4 "endothelial cell: 8.1;ependymal cell: 2.6;vascular associated smooth muscle cell: 2.5" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 82.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 5 "T-cells: 1.7" "Cancer enriched" "Detected in many" 6 "skin cancer: 47.4" "Adipose visceral - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in some" "Region enhanced" "Detected in single" "cerebellum: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029398, HPA062074" Uncertain Approved "Actin filaments" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Endothelial cells - Vasculature" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Actin filaments" "HPA029398: , HPA062074: " "unprognostic (4.56e-1)" "unprognostic (1.21e-1)" "unprognostic (2.11e-1)" "unprognostic (5.46e-3)" "unprognostic (4.81e-3)" "unprognostic (8.02e-2)" "unprognostic (2.03e-3)" "unprognostic (1.14e-1)" "unprognostic (5.79e-3)" "unprognostic (6.27e-3)" "potential prognostic favorable (4.61e-4)" "unprognostic (4.13e-3)" "unprognostic (1.01e-1)" "unprognostic (1.55e-2)" "potential prognostic favorable (6.42e-4)" "unprognostic (2.13e-1)" "unprognostic (7.93e-3)" "unprognostic (3.36e-2)" "unprognostic (1.80e-1)" "unprognostic (1.48e-2)" "unprognostic (9.24e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-1)" "unprognostic (1.15e-1)" "unprognostic (7.55e-2)" "unprognostic (6.15e-2)" "unprognostic (7.74e-3)" "unprognostic (5.29e-3)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (6.74e-3)" FAM174B "LOC400451, MGC102891" ENSG00000185442 "Family with sequence similarity 174 member B" Q3ZCQ3 15 92617448-92809884 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 75.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 217.2;Neutrophils: 219.3;Transitional alveolar cells: 175.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.9" "Group enriched" "Detected in many" 7 "dendritic cells: 3.5;granulocytes: 2.9;T-cells: 8.9" "Cancer enhanced" "Detected in many" "prostate cancer: 66.4" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Microglia and Neuropil: 355185.7;Pancreas epithelial cells: 1382493.1" "Group enriched" "Detected in some" 8903 "pancreas: 1186234.8;salivary gland: 594275.9" HPA015306 Approved Approved "Intermediate filaments" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 60: Stomach - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 24: Neutrophils - Innate immunity signal integration" "Intermediate filaments" "HPA015306: " "unprognostic (3.10e-2)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (9.18e-2)" "unprognostic (3.22e-1)" "unprognostic (9.08e-2)" "unprognostic (6.65e-2)" "unprognostic (1.47e-1)" "unprognostic (5.15e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (7.34e-4)" "unprognostic (5.89e-2)" "unprognostic (6.66e-2)" "unprognostic (1.12e-1)" "unprognostic (1.41e-2)" "potential prognostic favorable (7.37e-4)" "unprognostic (4.40e-1)" "unprognostic (1.44e-2)" "unprognostic (4.25e-1)" "unprognostic (7.61e-2)" "unprognostic (2.35e-1)" "unprognostic (1.13e-1)" "unprognostic (8.65e-2)" "unprognostic (5.47e-2)" "unprognostic (3.23e-2)" "unprognostic (4.61e-2)" "unprognostic (8.66e-3)" "unprognostic (7.31e-2)" "unprognostic (3.13e-1)" "unprognostic (2.02e-2)" "unprognostic (3.73e-3)" FAM184A "C6orf60, FLJ13942" ENSG00000111879 "Family with sequence similarity 184 member A" Q8NB25 6 118959763-119149387 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 255.6;Astrocytes: 327.2;Bergmann glia: 334.5;Corticotrophs: 292.7;Cytotrophoblasts: 228.5;Ependymal cells: 471.1;Pituicytes/FSCs: 305.2;Pituitary stem cells: 228.7;Respiratory ciliated cells: 225.1;Salivary myoepithelial cells: 263.9;Syncytiotrophoblasts: 794.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 471.1;Glial cells: 334.5;Trophoblast cells: 794.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.9" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Smooth muscle cells: 2349605.8" "Tissue enhanced" "Detected in some" "lung: 1305862.0" HPA034571 Uncertain Supported "Vesicles,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 16 "Centriolar satellite, Basal body, Cytosol" Vesicles "HPA034571: " "unprognostic (5.29e-2)" "unprognostic (1.05e-1)" "unprognostic (3.72e-2)" "unprognostic (2.03e-2)" "unprognostic (1.64e-1)" "unprognostic (2.16e-1)" "unprognostic (1.35e-1)" "unprognostic (2.23e-1)" "unprognostic (2.25e-1)" "unprognostic (2.99e-2)" "unprognostic (4.08e-2)" "unprognostic (3.04e-2)" "unprognostic (2.11e-1)" "unprognostic (2.84e-3)" "unprognostic (1.50e-2)" "unprognostic (8.01e-2)" "unprognostic (1.12e-1)" "unprognostic (6.97e-2)" "unprognostic (1.09e-2)" "potential prognostic favorable (4.20e-4)" "unprognostic (4.26e-1)" "unprognostic (3.91e-2)" "unprognostic (7.86e-2)" "unprognostic (1.85e-1)" "unprognostic (7.82e-3)" "unprognostic (1.34e-1)" "unprognostic (1.02e-2)" FAM186A LOC121006 ENSG00000185958 "Family with sequence similarity 186 member A" A6NE01 12 50326230-50396622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 14.2" "Group enriched" "Detected in many" 8 "Early spermatids: 602.3;Late primary spermatocytes: 187.8" "Cell type enriched" "Detected in many" 25 "Spermatogenic cell types: 602.3" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 11581 "Pancreatic islets: 1158096.7" "Tissue enriched" "Detected in single" 38163 "pancreas: 3816304.3" "HPA047128, HPA064735" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 9: Non-specific - Receptor signaling" "Cluster 35: RS4;11 - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA047128: , HPA064735: " "unprognostic (4.54e-2)" "unprognostic (1.73e-2)" FAM187A ENSG00000214447 "Family with sequence similarity 187 member A" A6NFU0 17 44899774-44905390 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA056723 Approved Acrosome NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 21: Lymphoma - Adaptive immune response" Acrosome "HPA056723: " "unprognostic (1.33e-2)" "unprognostic (1.06e-1)" "unprognostic (1.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.07e-1)" "unprognostic (2.29e-1)" "unprognostic (4.55e-1)" "potential prognostic favorable (4.85e-5)" "unprognostic (1.30e-1)" "unprognostic (4.34e-2)" "unprognostic (8.28e-2)" "unprognostic (3.40e-3)" "unprognostic (6.83e-3)" "unprognostic (8.49e-2)" "unprognostic (8.45e-2)" "unprognostic (2.69e-1)" "unprognostic (2.64e-1)" "unprognostic (1.23e-3)" "unprognostic (2.49e-2)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (4.40e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-2)" FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 250.7;Erythrocytes: 276.4;Hepatocytes: 176.2" "Cell type enhanced" "Detected in all" "Erythrocytes: 276.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Large ducts: 501707.3" "Tissue enriched" "Detected in single" 671 "intestine: 67051.6" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 58 "Plasma membrane, Cytosol" "HPA042652: " "unprognostic (8.26e-2)" "unprognostic (1.62e-1)" "unprognostic (4.53e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (1.12e-1)" "unprognostic (3.37e-2)" "unprognostic (5.77e-2)" "unprognostic (4.34e-2)" "potential prognostic favorable (7.61e-6)" "unprognostic (3.94e-2)" "unprognostic (3.96e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (7.15e-4)" "unprognostic (1.50e-1)" "unprognostic (1.43e-1)" "unprognostic (1.04e-1)" "unprognostic (1.98e-1)" "unprognostic (1.46e-1)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (2.13e-1)" "unprognostic (2.20e-2)" "unprognostic (4.99e-3)" "unprognostic (7.73e-2)" "unprognostic (1.14e-1)" "unprognostic (6.07e-2)" "unprognostic (9.22e-2)" "unprognostic (1.03e-3)" FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.0;Early spermatids: 171.5;Late spermatids: 117.5;Oligodendrocytes: 106.7;Retinal horizontal cells: 140.2;Rod photoreceptor cells: 185.9;Somatotrophs: 81.2" "Cell type enhanced" "Detected in many" "Glial cells: 106.7;Neuronal cells: 185.9;Spermatogenic cell types: 171.5" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 63.0;oligodendrocyte: 141.0" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 23.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Neuroblastoma: 49.6" "Adrenal gland - Adrenal cortex cells, Kidney - Ascending Loop of Henle cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 20: Non-specific - Transcription regulation" 1 "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: , HPA075616: " "unprognostic (7.81e-2)" "unprognostic (1.44e-2)" "unprognostic (2.00e-2)" "unprognostic (2.01e-1)" "unprognostic (3.77e-3)" "unprognostic (1.85e-1)" "potential prognostic favorable (4.95e-4)" "unprognostic (4.47e-2)" "unprognostic (6.14e-2)" "unprognostic (1.62e-1)" "unprognostic (2.44e-2)" "unprognostic (4.18e-2)" "unprognostic (3.34e-2)" "unprognostic (9.27e-3)" "unprognostic (7.28e-2)" "unprognostic (3.61e-1)" "unprognostic (3.35e-3)" "unprognostic (7.29e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.06e-4)" "unprognostic (7.20e-2)" "unprognostic (1.41e-1)" "unprognostic (7.39e-2)" "unprognostic (8.08e-2)" "unprognostic (4.84e-2)" "unprognostic (1.97e-3)" "unprognostic (8.34e-2)" "unprognostic (1.81e-1)" "unprognostic (5.56e-2)" FAM240C ENSG00000216921 "Family with sequence similarity 240 member C" A0A1B0GVR7 2 241893988-241902551 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "tongue: 209.9" "Cell type enhanced" "Detected in some" "Astrocytes: 2.2;Granulosa cells: 1.6;Late spermatids: 8.4;Myosatellite cells: 9.5;Pancreatic acinar cells: 1.9;Parietal cells: 1.8;Thymic myoid cells: 6.8" "Cell type enhanced" "Detected in some" "Spermatogenic cell types: 8.4;Stem cells: 9.5;Stromal cells: 6.8" "Cell type enhanced" "Detected in some" "fibroblast: 2.4;lower rhombic lip: 3.0" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 8.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Cell type enriched" "Detected in single" 161248 "Skeletal myofibers: 16124804.1" "Tissue enriched" "Detected in single" 95072 "skeletal muscle: 9507178.1" HPA073342 Approved Nucleoplasm NA NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA073342: " "unprognostic (3.26e-2)" "unprognostic (1.76e-2)" "unprognostic (3.71e-2)" "unprognostic (3.55e-1)" "unprognostic (1.84e-1)" "unprognostic (1.78e-2)" "unprognostic (1.70e-1)" FAM3A "2-19, DXS560S, XAP-7" ENSG00000071889 "FAM3 metabolism regulating signaling molecule A" P98173 X 154506159-154516242 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 117.7;Esophageal apical cells: 131.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 941118.1;Pancreatic islets: 719202.9" "Tissue enriched" "Detected in many" "pancreas: 344558.0" "CAB025016, HPA035268, HPA056991" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" "Secreted to blood" "No annotated function" Yes No "Cluster 41: Basophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB025016: , HPA035268: , HPA056991: " "unprognostic (7.07e-2)" "unprognostic (4.38e-2)" "unprognostic (7.93e-3)" "unprognostic (2.08e-1)" "unprognostic (6.76e-3)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (6.64e-2)" "unprognostic (5.94e-2)" "unprognostic (8.98e-2)" "potential prognostic favorable (6.40e-4)" "unprognostic (4.15e-2)" "unprognostic (4.83e-2)" "unprognostic (2.57e-1)" "unprognostic (1.81e-1)" "unprognostic (4.37e-2)" "unprognostic (4.17e-1)" "unprognostic (9.28e-2)" "unprognostic (4.71e-3)" "unprognostic (3.89e-2)" "unprognostic (4.00e-1)" "unprognostic (2.01e-1)" "unprognostic (6.49e-2)" "unprognostic (5.42e-2)" "unprognostic (1.43e-1)" "unprognostic (1.29e-1)" "unprognostic (3.82e-1)" "unprognostic (2.43e-1)" "unprognostic (1.21e-1)" FAM43A FLJ90022 ENSG00000185112 "Family with sequence similarity 43 member A" Q8N2R8 3 194685883-194689037 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 47.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 97.5;Extravillous trophoblasts: 128.3;Lymphatic endothelial cells: 122.3;Podocytes: 53.9;Prostatic glandular cells: 82.1;Respiratory ionocytes: 101.6;Syncytiotrophoblasts: 203.9;Vascular endothelial cells: 88.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 122.3;Trophoblast cells: 203.9" "Cell type enhanced" "Detected in many" "endothelial cell: 56.2;fibroblast: 67.5;lower rhombic lip: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Skin - Hair cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 8405 "Large ducts: 840478.0" "Tissue enriched" "Detected in single" 109 "intestine: 10932.7" HPA048345 Uncertain Approved Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 16 Vesicles "HPA048345: " "unprognostic (1.69e-1)" "unprognostic (1.47e-1)" "unprognostic (5.57e-2)" "unprognostic (6.22e-2)" "unprognostic (1.97e-1)" "unprognostic (1.18e-1)" "unprognostic (5.86e-3)" "unprognostic (5.44e-2)" "unprognostic (4.78e-2)" "unprognostic (1.84e-1)" "unprognostic (1.89e-3)" "unprognostic (3.34e-2)" "unprognostic (1.10e-2)" "unprognostic (5.07e-2)" "unprognostic (6.66e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (2.26e-3)" "unprognostic (1.89e-2)" "unprognostic (1.17e-1)" "unprognostic (1.12e-1)" "unprognostic (1.11e-2)" "unprognostic (1.16e-1)" "unprognostic (4.95e-2)" "unprognostic (5.20e-2)" "unprognostic (3.82e-1)" "unprognostic (8.38e-3)" "unprognostic (4.37e-2)" "unprognostic (2.18e-1)" "unprognostic (8.66e-3)" "unprognostic (3.63e-1)" FAM50B "D6S2654E, X5L" ENSG00000145945 "Family with sequence similarity 50 member B" Q9Y247 6 3849373-3851320 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Loop of henle epithelial cells: 2.1;Papillary tip epithelial cells: 1.8;Podocytes: 1.0;Proximal tubule cells: 1.2;Renal collecting duct intercalated cells: 1.2;Renal collecting duct principal cells: 2.0;Thymic myoid cells: 1.4" "Group enriched" "Detected in some" 4 "Ductal cells: 2.0;Renal nephron cells: 2.1;Stromal cells: 1.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Neurons: 1353044.2" "Group enriched" "Detected in some" 7268 "intestine: 909610.4;pancreas: 544032.2" "HPA064111, HPA067817" Approved Approved "Nucleoplasm,Cytokinetic bridge,Midbody" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 43 Nucleoplasm "Cytokinetic bridge, Midbody" "HPA064111: , HPA067817: " "unprognostic (1.21e-1)" "unprognostic (9.61e-2)" "unprognostic (6.32e-2)" "unprognostic (2.13e-1)" "unprognostic (3.85e-3)" "unprognostic (2.26e-2)" "unprognostic (5.50e-3)" "unprognostic (1.99e-3)" "unprognostic (1.30e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (8.10e-9)" "unprognostic (9.00e-2)" "potential prognostic favorable (8.15e-4)" "unprognostic (1.41e-2)" "unprognostic (3.20e-1)" "unprognostic (3.41e-1)" "unprognostic (1.40e-1)" "unprognostic (1.06e-1)" "unprognostic (4.12e-3)" "unprognostic (1.69e-1)" "unprognostic (3.55e-1)" "unprognostic (2.52e-1)" "unprognostic (1.21e-1)" "unprognostic (2.35e-1)" "unprognostic (1.51e-1)" "unprognostic (1.30e-2)" "unprognostic (1.52e-1)" "unprognostic (2.22e-1)" "unprognostic (1.11e-1)" "unprognostic (3.10e-1)" "unprognostic (1.71e-1)" FAM76A MGC34648 ENSG00000009780 "Family with sequence similarity 76 member A" Q8TAV0 1 27725961-27763116 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 168.2;Late spermatids: 150.5" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 168.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044762, HPA077897" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 "Nucleoplasm, Cytosol" "HPA044762: , HPA077897: " "unprognostic (9.72e-3)" "unprognostic (9.60e-2)" "unprognostic (1.16e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (1.65e-1)" "unprognostic (6.67e-2)" "unprognostic (3.91e-1)" "unprognostic (2.20e-3)" "potential prognostic unfavorable (7.98e-4)" "potential prognostic favorable (6.24e-5)" "unprognostic (4.21e-3)" "potential prognostic favorable (8.96e-7)" "unprognostic (7.04e-3)" "unprognostic (1.18e-1)" "unprognostic (2.81e-3)" "unprognostic (2.48e-1)" "unprognostic (1.61e-1)" "unprognostic (1.53e-1)" "unprognostic (1.76e-1)" "unprognostic (4.34e-2)" "unprognostic (1.15e-1)" "unprognostic (1.82e-2)" "unprognostic (3.32e-2)" "unprognostic (1.75e-1)" "unprognostic (3.55e-2)" "unprognostic (1.28e-2)" "unprognostic (1.40e-1)" "unprognostic (1.55e-1)" "unprognostic (4.27e-2)" "unprognostic (2.71e-1)" FAM76B MGC33371 ENSG00000077458 "Family with sequence similarity 76 member B" Q5HYJ3 11 95768953-95790409 "Predicted intracellular proteins, Predicted membrane proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.3" "Group enriched" "Detected in all" 4 "Early spermatids: 320.0;Late spermatids: 665.4" "Cell type enriched" "Detected in all" 10 "Spermatogenic cell types: 665.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 2755399.0" "Tissue enriched" "Detected in some" "lymphoid tissue: 297888.4" HPA036608 Approved Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 10 Nucleoplasm "Nucleoli fibrillar center" "HPA036608: " "unprognostic (5.94e-3)" "unprognostic (1.32e-2)" "unprognostic (7.93e-2)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (5.21e-2)" "unprognostic (1.88e-1)" "unprognostic (1.88e-2)" "unprognostic (5.80e-3)" "unprognostic (6.21e-3)" "validated prognostic favorable (7.68e-5)" "validated prognostic favorable (4.10e-4)" "unprognostic (1.36e-1)" "unprognostic (3.06e-1)" "unprognostic (3.70e-2)" "unprognostic (1.72e-1)" "unprognostic (1.62e-2)" "unprognostic (1.93e-1)" "unprognostic (3.03e-2)" "unprognostic (2.16e-1)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (4.04e-4)" "unprognostic (3.65e-3)" "unprognostic (2.37e-2)" "unprognostic (1.40e-3)" "unprognostic (7.07e-2)" "unprognostic (4.73e-2)" "unprognostic (7.65e-2)" "unprognostic (3.71e-1)" "unprognostic (4.33e-2)" "unprognostic (8.58e-2)" FAM83D "C20orf129, CHICA, dJ616B8.3" ENSG00000101447 "Family with sequence similarity 83 member D" Q9H4H8 20 38926312-38953106 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 81.8;intestine: 76.6;smooth muscle: 88.9" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 561.4;Syncytiotrophoblasts: 261.4" "Group enriched" "Detected in many" 5 "Apical squamous epithelial cells: 561.4;Trophoblast cells: 261.4" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 33.1;hippocampal CA1-3: 10.1;medium spiny neuron: 11.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "B-cells: 1.1;NK-cells: 1.1;T-cells: 2.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells, Spleen - Mitotic cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 587 "Granulosa cells: 58748.9" "Tissue enriched" "Detected in some" "intestine: 3884951.9" "HPA049333, HPA060854" Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 84: Apical squamous epithelium - Cornification" 26 "Mitotic spindle" "Microtubules, Cytokinetic bridge, Cytosol" "HPA049333: , HPA060854: " "unprognostic (2.49e-1)" "unprognostic (1.87e-2)" "unprognostic (5.33e-2)" "unprognostic (3.09e-1)" "unprognostic (1.95e-1)" "unprognostic (9.30e-2)" "unprognostic (6.62e-2)" "unprognostic (3.39e-3)" "unprognostic (9.12e-2)" "potential prognostic unfavorable (5.10e-5)" "unprognostic (6.22e-2)" "unprognostic (8.73e-3)" "potential prognostic unfavorable (5.91e-9)" "validated prognostic unfavorable (1.31e-5)" "validated prognostic unfavorable (1.00e-6)" "validated prognostic unfavorable (2.17e-5)" "validated prognostic unfavorable (1.89e-4)" "unprognostic (2.52e-3)" "unprognostic (5.35e-2)" "unprognostic (2.41e-2)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (3.68e-5)" "unprognostic (2.68e-1)" "unprognostic (2.31e-2)" "unprognostic (1.70e-1)" "unprognostic (9.30e-3)" "unprognostic (2.71e-2)" "unprognostic (1.51e-2)" "unprognostic (5.19e-2)" "unprognostic (1.13e-1)" FAM83E FLJ20200 ENSG00000105523 "Family with sequence similarity 83 member E" Q2M2I3 19 48599961-48615076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.9;salivary gland: 28.6;stomach 1: 35.3" "Cell type enhanced" "Detected in many" "Colonocytes: 125.6;Enteric stem cells: 72.4;Enteric transient amplifying cells: 65.9;Enterocytes: 67.6;Foveolar cells: 252.7;Goblet cells: 268.5;Neuroendocrine cells: 72.8;Respiratory secretory cells: 65.6;Tuft cells: 80.7" "Cell type enhanced" "Detected in many" "Enterocytes: 125.6;Gastric glandular cells: 252.7;Goblet cells: 268.5" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 12.3;Gastric cancer: 9.9" "Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 649 "Alveolar cell types: 95258.0;Fallopian tube cells: 63578.9;Large ducts: 35845.2" "Group enriched" "Detected in some" 283 "intestine: 21998.3;salivary gland: 34595.6" "HPA049305, HPA075968" Uncertain Approved Vesicles,Cytosol NA NA "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 1 Cytosol Vesicles "HPA049305: , HPA075968: " "unprognostic (1.22e-1)" "unprognostic (2.98e-1)" "unprognostic (7.85e-2)" "unprognostic (1.93e-2)" "unprognostic (2.53e-1)" "unprognostic (3.09e-2)" "unprognostic (1.31e-3)" "unprognostic (9.92e-2)" "unprognostic (2.01e-1)" "unprognostic (6.84e-2)" "unprognostic (1.15e-1)" "unprognostic (6.12e-2)" "unprognostic (1.17e-1)" "unprognostic (9.84e-2)" "unprognostic (1.12e-1)" "unprognostic (3.25e-2)" "unprognostic (5.32e-2)" "unprognostic (1.74e-1)" "unprognostic (5.19e-3)" "unprognostic (1.51e-2)" "unprognostic (1.20e-1)" "unprognostic (8.22e-2)" FAM98C FLJ44669 ENSG00000130244 "Family with sequence similarity 98 member C" Q17RN3 19 38403093-38409088 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 90.2;Esophageal apical cells: 62.8" "Cell type enhanced" "Detected in all" "Enterocytes: 90.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA040930, HPA041730" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 14 "Nucleoplasm, Nucleoli" Cytosol "HPA040930: , HPA041730: " "unprognostic (3.64e-2)" "unprognostic (1.13e-1)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "unprognostic (2.39e-1)" "unprognostic (2.33e-1)" "unprognostic (8.09e-3)" "unprognostic (1.78e-1)" "potential prognostic favorable (6.12e-6)" "unprognostic (1.86e-1)" "unprognostic (2.53e-2)" "unprognostic (8.55e-2)" "unprognostic (5.56e-2)" "unprognostic (6.04e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.53e-3)" "unprognostic (2.30e-2)" "unprognostic (2.27e-1)" "unprognostic (6.87e-2)" "unprognostic (3.02e-2)" "unprognostic (9.81e-2)" "unprognostic (2.38e-1)" "unprognostic (1.11e-1)" "unprognostic (3.32e-3)" "unprognostic (4.24e-2)" "unprognostic (4.40e-2)" "unprognostic (1.38e-1)" FAN1 "KIAA1018, MTMR15" ENSG00000198690 "FANCD2 and FANCI associated nuclease 1" Q9Y2M0 15 30890559-30943108 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair" "Endonuclease, Exonuclease, Hydrolase, Nuclease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Bergmann glia: 42.0;Brain excitatory neurons: 38.5;Brain inhibitory neurons: 36.1;Choroid plexus epithelial cells: 52.8;Distal convoluted tubule cells: 52.3;Ependymal cells: 33.4;Loop of henle epithelial cells: 43.7;Microglia: 33.0;Oligodendrocyte progenitor cells: 40.4;Oligodendrocytes: 63.9;Other brain neurons: 43.0;Proximal tubule cells: 36.1;Renal collecting duct intercalated cells: 40.5;Renal collecting duct principal cells: 32.2;Renal connecting tubule cells: 45.5" "Group enriched" "Detected in many" 4 "Ciliated cells: 52.8;Ductal cells: 45.5;Glial cells: 63.9;Neuronal cells: 43.0;Renal nephron cells: 52.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 49937 "Capillaries: 2319019.7;Distal tubules: 7458985.5;Neurons: 5203028.4" "Not detected" "Not detected" HPA048198 Approved "Nucleoplasm,Cytokinetic bridge,Primary cilium,Cytosol" Yes NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 10 "Nucleoplasm, Cytosol" "Cytokinetic bridge, Primary cilium" "HPA048198: " "unprognostic (1.73e-2)" "unprognostic (6.89e-3)" "unprognostic (1.79e-3)" "unprognostic (6.62e-2)" "potential prognostic favorable (2.21e-4)" "unprognostic (1.53e-1)" "unprognostic (4.29e-3)" "unprognostic (6.69e-3)" "unprognostic (2.72e-2)" "potential prognostic favorable (1.23e-4)" "unprognostic (1.19e-1)" "unprognostic (5.50e-2)" "unprognostic (6.61e-2)" "unprognostic (7.83e-2)" "unprognostic (6.62e-2)" "unprognostic (7.06e-2)" "unprognostic (9.56e-3)" "unprognostic (3.66e-1)" "unprognostic (3.48e-3)" "unprognostic (2.16e-1)" "unprognostic (9.33e-3)" "unprognostic (2.25e-2)" "unprognostic (1.24e-1)" "unprognostic (7.57e-3)" "unprognostic (7.67e-3)" "unprognostic (2.70e-1)" "unprognostic (3.19e-1)" "unprognostic (1.40e-1)" "unprognostic (3.02e-1)" "unprognostic (1.09e-1)" FANCD2 "FA-D2, FACD, FAD, FANCD" ENSG00000144554 "FA complementation group D2" Q9BXW9 3 10026370-10101932 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.8;lymphoid tissue: 10.0" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 59.3;Early primary spermatocytes: 103.7;Erythrocyte progenitors: 90.2;Megakaryocyte progenitors: 69.7;Monocyte progenitors: 72.8;Neutrophil progenitors: 52.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 90.2;Megakaryocytes: 69.7;Mononuclear phagocytes: 72.8;Spermatogenic cell types: 103.7" "Cell type enhanced" "Detected in many" "leukocyte: 15.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Spleen - B-cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 34314 "Granulosa cells: 3337194.4;Neutrophils: 4619790.6;Oocytes: 2337134.2" "Tissue enriched" "Detected in single" 2207 "bone marrow: 220703.7" "CAB016117, HPA063742" Approved Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" No No "Cluster 32: Basophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 34: Testis cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 88 "Nucleoplasm, Nuclear bodies" "Nucleoli, Cytosol" "CAB016117: , HPA063742: " "unprognostic (1.27e-1)" "unprognostic (3.27e-3)" "unprognostic (5.45e-2)" "unprognostic (2.30e-1)" "unprognostic (1.17e-2)" "unprognostic (2.95e-1)" "unprognostic (2.26e-1)" "unprognostic (2.99e-3)" "unprognostic (3.31e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (5.41e-3)" "unprognostic (1.30e-1)" "unprognostic (3.89e-2)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (6.14e-4)" "unprognostic (1.71e-1)" "unprognostic (1.69e-2)" "unprognostic (7.62e-3)" "unprognostic (3.60e-1)" "unprognostic (6.00e-2)" "unprognostic (1.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.19e-3)" "unprognostic (1.69e-2)" "unprognostic (6.85e-2)" "unprognostic (3.68e-3)" "unprognostic (3.55e-1)" "unprognostic (1.52e-3)" "unprognostic (2.51e-2)" FAR1 "FLJ22728, MLSTD2, SDR10E1" ENSG00000197601 "Fatty acyl-CoA reductase 1" Q8WVX9 11 13668668-13732346 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Cataract, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Foveolar cells: 432.5;Neutrophil progenitors: 670.4;Neutrophils: 682.9" "Cell type enhanced" "Detected in all" "Neutrophils: 682.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" "cerebral cortex: 5170124.9;lymphoid tissue: 1988582.7" HPA017322 Approved Supported Peroxisomes NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 Peroxisomes "HPA017322: " "unprognostic (1.68e-1)" "unprognostic (1.80e-2)" "unprognostic (3.20e-2)" "unprognostic (5.27e-2)" "unprognostic (3.26e-2)" "unprognostic (2.87e-1)" "unprognostic (3.43e-2)" "unprognostic (1.06e-1)" "unprognostic (4.97e-1)" "unprognostic (5.15e-3)" "unprognostic (5.09e-2)" "unprognostic (4.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.80e-1)" "unprognostic (2.48e-1)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (3.45e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-3)" "potential prognostic unfavorable (8.60e-4)" "unprognostic (3.02e-2)" "unprognostic (3.41e-3)" "unprognostic (1.71e-2)" "unprognostic (2.53e-3)" "unprognostic (2.23e-1)" "unprognostic (3.40e-1)" "unprognostic (9.98e-2)" "unprognostic (1.32e-1)" "unprognostic (4.10e-2)" "unprognostic (2.50e-1)" FARSA "CML33, FARSL, FARSLA" ENSG00000179115 "Phenylalanyl-tRNA synthetase subunit alpha" Q9Y285 19 12922479-12934037 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 106.6;Syncytiotrophoblasts: 122.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Neurons: 303279967.3" "Low tissue specificity" "Detected in all" HPA001911 Enhanced Approved Cytosol NA NA 17000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 21 Cytosol "HPA001911: " "unprognostic (7.94e-2)" "unprognostic (2.71e-2)" "unprognostic (3.92e-2)" "unprognostic (9.88e-3)" "unprognostic (2.29e-1)" "unprognostic (1.18e-1)" "unprognostic (1.21e-1)" "unprognostic (1.65e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (4.54e-4)" "potential prognostic favorable (2.62e-4)" "unprognostic (9.32e-2)" "unprognostic (9.16e-2)" "unprognostic (3.87e-3)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (2.04e-2)" "unprognostic (1.85e-2)" "potential prognostic favorable (5.50e-4)" "unprognostic (5.30e-2)" "unprognostic (4.02e-2)" "unprognostic (1.04e-1)" "unprognostic (9.44e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (8.65e-2)" "unprognostic (8.42e-3)" "unprognostic (3.26e-1)" "unprognostic (1.20e-1)" "unprognostic (2.40e-1)" FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 364.3;breast: 270.5;liver: 192.6" "Cell type enriched" "Detected in many" 4 "Breast lactating cells: 3382.5" "Cell type enriched" "Detected in all" 4 "Secretory cells: 3382.5" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 93.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Alveolar cells type 2, Pituitary gland - Corticotropes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Hepatocytes: 2583431982.3" "Tissue enriched" "Detected in all" "liver: 2006681020.4" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3300000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" 60 "Plasma membrane, Cytosol" "CAB005192: , CAB015417: , HPA006461: , HPA056108: " "unprognostic (2.78e-2)" "unprognostic (6.23e-2)" "unprognostic (8.08e-2)" "potential prognostic unfavorable (8.58e-6)" "unprognostic (6.36e-2)" "unprognostic (8.71e-2)" "unprognostic (4.76e-2)" "unprognostic (1.46e-1)" "unprognostic (5.38e-2)" "unprognostic (7.40e-3)" "potential prognostic unfavorable (2.84e-4)" "unprognostic (8.13e-3)" "potential prognostic unfavorable (3.88e-4)" "unprognostic (3.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.89e-1)" "unprognostic (1.90e-2)" "unprognostic (1.11e-2)" "unprognostic (1.98e-2)" "unprognostic (1.51e-1)" "unprognostic (4.17e-3)" "unprognostic (7.36e-2)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (7.55e-2)" "unprognostic (7.18e-2)" "unprognostic (8.07e-2)" "unprognostic (5.28e-2)" "unprognostic (2.00e-1)" "unprognostic (1.73e-2)" "unprognostic (5.37e-2)" FASTKD1 FLJ21901 ENSG00000138399 "FAST kinase domains 1" Q53R41 2 169528508-169573875 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 213.1;Myonuclei: 172.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 213.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Distal tubules: 2621416.1;Large ducts: 9369911.5" "Group enriched" "Detected in some" 85 "intestine: 13038.9;lymphoid tissue: 3995.6" HPA043719 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 5: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 42 Mitochondria Nucleoplasm "HPA043719: " "unprognostic (1.51e-1)" "unprognostic (4.33e-3)" "unprognostic (4.09e-1)" "unprognostic (6.45e-2)" "unprognostic (4.24e-2)" "unprognostic (6.45e-3)" "unprognostic (9.83e-2)" "unprognostic (5.14e-2)" "unprognostic (5.62e-2)" "unprognostic (4.26e-3)" "unprognostic (1.79e-3)" "unprognostic (6.51e-3)" "unprognostic (4.56e-2)" "unprognostic (7.34e-3)" "unprognostic (1.14e-1)" "unprognostic (1.26e-1)" "unprognostic (2.57e-1)" "unprognostic (1.32e-1)" "unprognostic (1.97e-1)" "unprognostic (1.07e-2)" "unprognostic (1.10e-1)" "unprognostic (2.18e-1)" "unprognostic (1.27e-2)" "unprognostic (7.99e-2)" "unprognostic (6.71e-3)" "unprognostic (2.95e-1)" "unprognostic (5.74e-3)" "unprognostic (6.22e-2)" "unprognostic (1.39e-1)" "unprognostic (7.01e-2)" "unprognostic (3.67e-2)" FASTKD2 KIAA0971 ENSG00000118246 "FAST kinase domains 2" Q9NYY8 2 206765357-206796189 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribosome biogenesis" "RNA-binding, rRNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "intestine: 3086614.0;lymphoid tissue: 4702541.9" HPA067191 Supported Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 23 Mitochondria "HPA067191: " "unprognostic (2.23e-1)" "unprognostic (5.47e-2)" "unprognostic (1.93e-1)" "unprognostic (1.32e-2)" "potential prognostic favorable (1.27e-4)" "unprognostic (1.63e-2)" "unprognostic (1.25e-1)" "unprognostic (5.44e-2)" "unprognostic (2.45e-2)" "unprognostic (4.84e-3)" "potential prognostic favorable (9.57e-9)" "unprognostic (5.11e-3)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (7.87e-4)" "unprognostic (5.33e-2)" "unprognostic (3.55e-3)" "unprognostic (6.72e-2)" "unprognostic (6.98e-2)" "unprognostic (1.97e-1)" "unprognostic (2.26e-1)" "unprognostic (3.61e-1)" "unprognostic (1.73e-3)" "unprognostic (3.21e-2)" "unprognostic (6.63e-2)" "unprognostic (6.54e-3)" "unprognostic (3.11e-2)" "unprognostic (1.53e-2)" "unprognostic (1.37e-1)" "unprognostic (3.49e-1)" "unprognostic (1.34e-2)" "unprognostic (7.98e-2)" FAU "asr1, FLJ22986, Fub1, Fubi, MNSFbeta, RPS30, S30" ENSG00000149806 "FAU ubiquitin like and ribosomal protein S30 fusion" P62861 11 65120630-65122177 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 108020104.8" "Tissue enhanced" "Detected in all" "pancreas: 183754998.8" HPA059015 Supported Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" No No "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 64 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA059015: " "unprognostic (3.79e-3)" "unprognostic (3.32e-3)" "unprognostic (9.15e-2)" "unprognostic (2.20e-2)" "unprognostic (1.12e-1)" "unprognostic (3.34e-2)" "unprognostic (9.78e-2)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (2.82e-1)" "unprognostic (3.28e-1)" "unprognostic (2.77e-1)" "unprognostic (4.35e-2)" "unprognostic (4.87e-2)" "unprognostic (1.09e-2)" "unprognostic (2.16e-1)" "unprognostic (4.48e-3)" "unprognostic (2.65e-1)" "unprognostic (1.90e-2)" "unprognostic (1.11e-2)" "unprognostic (2.31e-1)" "unprognostic (3.58e-2)" "unprognostic (4.02e-1)" "unprognostic (1.46e-1)" "unprognostic (2.12e-1)" "unprognostic (6.99e-2)" "unprognostic (1.11e-1)" "unprognostic (2.09e-1)" "unprognostic (8.54e-2)" "unprognostic (9.04e-2)" "unprognostic (7.39e-2)" FBF1 "ALB, FBF-1, FLJ00103, KIAA1863" ENSG00000188878 "Fas binding factor 1" Q8TES7 17 75909574-75941140 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 29.7" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 52.0" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 52.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 8057 "Fallopian tube cells: 805709.4" "Not detected" "Not detected" HPA023677 Supported "Primary cilium,Centrosome,Basal body" NA NA "Cluster 47: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 8 "Centrosome, Basal body" "Primary cilium" "HPA023677: " "unprognostic (1.56e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (5.00e-4)" "unprognostic (1.80e-1)" "unprognostic (1.69e-1)" "unprognostic (3.24e-2)" "unprognostic (2.15e-2)" "unprognostic (1.32e-1)" "unprognostic (1.28e-3)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (3.87e-8)" "unprognostic (5.04e-3)" "unprognostic (1.64e-1)" "unprognostic (2.02e-3)" "unprognostic (3.59e-2)" "unprognostic (2.87e-1)" "unprognostic (5.40e-3)" "unprognostic (1.17e-1)" "unprognostic (1.76e-2)" "unprognostic (1.90e-2)" "unprognostic (8.25e-3)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.36e-1)" "unprognostic (3.86e-1)" "unprognostic (1.61e-2)" "unprognostic (3.99e-3)" "unprognostic (2.14e-1)" "unprognostic (1.54e-1)" "unprognostic (7.05e-2)" "unprognostic (1.78e-1)" "unprognostic (2.43e-1)" FBN2 "CCA, DA9" ENSG00000138829 "Fibrillin 2" P35556 5 128257909-128659185 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Hormone "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "placenta: 63.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 721.7;Cardiomyocytes: 232.1;Cytotrophoblasts: 1452.5;Migrating cytotrophoblasts: 435.8;Pituitary stem cells: 485.1;Syncytiotrophoblasts: 379.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 721.7;Stem cells: 485.1;Trophoblast cells: 1452.5" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 117.3;midbrain-derived inhibitory: 237.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Lineage enriched" "Detected in single" 6 "monocytes: 2.2" "Cancer enhanced" "Detected in many" "Sarcoma: 46.8" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Region enhanced" "Detected in single" "olfactory bulb: 2.0" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 1920 "Smooth muscle cells: 192028.2" "Tissue enhanced" "Detected in many" "intestine: 31795125.6" "HPA012853, CAB026401" Enhanced Approved "Nucleoplasm,Primary cilium,Cytosol" "Secreted to blood" Hormone NA NA 4700000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 3: Choroid plexus - Cilium" "Cluster 3: Rhabdoid - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Cytosol "Nucleoplasm, Primary cilium" "CAB026401: , HPA012853: " "unprognostic (1.59e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-1)" "unprognostic (3.39e-2)" "unprognostic (6.04e-2)" "unprognostic (1.79e-2)" "potential prognostic favorable (4.70e-4)" "unprognostic (2.72e-1)" "unprognostic (6.24e-3)" "unprognostic (8.11e-3)" "unprognostic (2.49e-2)" "unprognostic (1.61e-1)" "unprognostic (2.61e-1)" "unprognostic (2.44e-1)" "unprognostic (5.10e-2)" "unprognostic (9.78e-2)" "unprognostic (8.50e-2)" "unprognostic (1.21e-1)" FBP1 FBP ENSG00000165140 "Fructose-bisphosphatase 1" P09467 9 94603133-94640249 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 289.1;kidney: 275.8;liver: 819.2" "Cell type enhanced" "Detected in many" "Breast lactating cells: 266.9;Enterocytes: 1019.3;Hepatocytes: 665.7;Prostatic club cells: 456.7;Prostatic hillock cells: 169.4;Urothelial cells: 472.4" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 472.4;Enterocytes: 1019.3;Glandular cells: 456.7;Hepatocytes: 665.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.4;leukocyte: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 403.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "breast cancer: 70.7" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Gonadotropes, Skeletal muscle - Macrophages, Skin - Inner root sheath cells, Spleen - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "Glomeruli: 416199472.8;Hepatocytes: 214347545.6;Proximal tubules: 429675555.7" "Group enriched" "Detected in all" "intestine: 316385120.9;kidney: 670476260.2;liver: 805610255.6" "HPA005857, HPA012513, CAB033869" Enhanced Approved Mitochondria NA NA 18000000 "Cluster 25: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 24 Mitochondria "CAB033869: , HPA005857: , HPA012513: " "potential prognostic favorable (8.84e-5)" "unprognostic (1.88e-2)" "unprognostic (4.70e-1)" "unprognostic (7.31e-2)" "unprognostic (2.20e-1)" "unprognostic (1.35e-1)" "unprognostic (3.13e-3)" "unprognostic (1.60e-2)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "validated prognostic favorable (1.81e-7)" "validated prognostic favorable (4.11e-5)" "unprognostic (2.19e-3)" "unprognostic (1.90e-3)" "unprognostic (2.10e-3)" "potential prognostic favorable (3.82e-4)" "unprognostic (3.20e-2)" "unprognostic (4.65e-2)" "unprognostic (4.66e-2)" "unprognostic (2.43e-1)" "unprognostic (6.81e-3)" "unprognostic (6.34e-2)" "potential prognostic favorable (4.91e-4)" "unprognostic (2.61e-1)" "unprognostic (9.24e-2)" "unprognostic (9.40e-3)" "unprognostic (8.05e-2)" "unprognostic (1.83e-1)" "unprognostic (5.68e-2)" "unprognostic (8.60e-2)" "unprognostic (1.34e-1)" FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593824 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "choroid plexus: 217.1;skeletal muscle: 706.1;tongue: 359.7" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 192.1;Differentiating spermatogonia: 15.1;Gastric chief cells: 68.8;Mucous neck cells: 37.2;Myonuclei: 87.7;Oocytes: 36.8;Parietal cells: 15.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 192.1;Gastric glandular cells: 68.8;Myocytes: 87.7;Oocytes: 36.8" "Cell type enriched" "Detected in some" 17 "choroid plexus epithelial cell: 170.6" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in many" 12 "choroid plexus: 155.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" "Glomeruli: 171040796.1;Proximal tubules: 140569622.7" "Group enriched" "Detected in many" "kidney: 52054936.8;liver: 31651300.8" "HPA012513, HPA077371" Enhanced Approved "Plasma membrane,Cytosol" NA NA 1900000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 8 "Plasma membrane, Cytosol" "HPA012513: , HPA077371: " "unprognostic (2.92e-1)" "unprognostic (2.03e-1)" "unprognostic (9.47e-2)" "unprognostic (2.51e-1)" "unprognostic (1.39e-2)" "unprognostic (3.21e-2)" "unprognostic (1.04e-2)" "unprognostic (5.31e-2)" "unprognostic (1.99e-2)" "unprognostic (3.64e-2)" FBXL17 "DKFZP434C1715, Fbl17, Fbx13, FBXO13" ENSG00000145743 "F-box and leucine rich repeat protein 17" Q9UF56 5 107859035-108382098 "Predicted intracellular proteins, Predicted membrane proteins" "Neurogenesis, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 1151.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "prostate cancer: 31.9" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Microglia and Neuropil: 162791.8;Neurons: 410754.6" "Tissue enriched" "Detected in single" 36 "cerebral cortex: 3623.9" "HPA036410, HPA036411" Uncertain Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 60: Prostate cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 38 Nucleoplasm "HPA036410: , HPA036411: " "unprognostic (1.20e-1)" "unprognostic (2.24e-2)" "unprognostic (5.87e-2)" "unprognostic (3.16e-2)" "unprognostic (6.62e-2)" "unprognostic (1.30e-2)" "unprognostic (4.47e-1)" "unprognostic (1.85e-1)" "unprognostic (2.31e-2)" "unprognostic (2.76e-2)" "validated prognostic favorable (1.97e-9)" "validated prognostic favorable (1.14e-4)" "unprognostic (3.39e-3)" "unprognostic (1.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.05e-2)" "unprognostic (7.95e-2)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (2.93e-2)" "unprognostic (1.66e-3)" "unprognostic (6.36e-2)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (6.87e-2)" "unprognostic (2.53e-2)" "unprognostic (5.27e-2)" "unprognostic (1.33e-1)" "unprognostic (7.90e-2)" "unprognostic (1.11e-2)" "unprognostic (9.66e-2)" FBXL18 "Fbl18, FLJ11467" ENSG00000155034 "F-box and leucine rich repeat protein 18" Q96ME1 7 5431335-5513809 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 89.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 4463882.1;Microglia and Neuropil: 4433120.4;Neurons: 4497826.1" "Tissue enriched" "Detected in some" "cerebral cortex: 1456787.0" HPA036049 Approved Nucleoplasm,Cytosol No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 10 Nucleoplasm Cytosol "HPA036049: " "unprognostic (7.59e-2)" "potential prognostic unfavorable (9.93e-4)" "unprognostic (1.86e-1)" "unprognostic (1.48e-3)" "unprognostic (4.18e-2)" "unprognostic (5.70e-1)" "unprognostic (4.47e-2)" "unprognostic (1.13e-1)" "unprognostic (2.26e-1)" "unprognostic (9.97e-3)" "unprognostic (1.59e-1)" "unprognostic (1.23e-1)" "unprognostic (4.45e-2)" "potential prognostic unfavorable (2.69e-6)" "unprognostic (7.42e-2)" "unprognostic (2.12e-3)" "unprognostic (2.41e-1)" "unprognostic (2.04e-1)" "unprognostic (4.30e-2)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (9.39e-5)" "unprognostic (1.71e-3)" "unprognostic (4.99e-3)" "unprognostic (7.29e-2)" "unprognostic (1.45e-1)" "unprognostic (3.26e-1)" "unprognostic (1.26e-1)" "unprognostic (2.75e-1)" "unprognostic (3.58e-2)" "unprognostic (1.00e-3)" "unprognostic (4.75e-2)" FBXL6 FBL6 ENSG00000182325 "F-box and leucine rich repeat protein 6" Q8N531 8 144355431-144359376 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 22.3;Enterocytes: 30.8" "Cell type enhanced" "Detected in many" "Enterocytes: 30.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1392 "Neutrophils: 139177.3" "Tissue enriched" "Detected in single" 14713 "lymphoid tissue: 1471253.5" HPA008867 Approved Nucleoplasm,Vesicles Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 104: Brain endothelial cells - Blood brain barrier" 49 Nucleoplasm Vesicles "HPA008867: " "unprognostic (2.04e-2)" "unprognostic (3.37e-3)" "unprognostic (1.34e-1)" "unprognostic (3.08e-1)" "unprognostic (3.55e-2)" "unprognostic (2.15e-1)" "unprognostic (2.98e-1)" "potential prognostic favorable (4.26e-4)" "unprognostic (5.92e-3)" "unprognostic (4.59e-1)" "unprognostic (2.32e-3)" "unprognostic (5.09e-3)" "unprognostic (7.19e-2)" "unprognostic (1.29e-1)" "unprognostic (6.26e-2)" "unprognostic (7.90e-2)" "unprognostic (5.81e-2)" "unprognostic (8.00e-2)" "unprognostic (2.85e-2)" "unprognostic (1.33e-2)" "unprognostic (1.85e-3)" "potential prognostic unfavorable (9.40e-4)" "unprognostic (1.95e-2)" "unprognostic (3.82e-2)" "unprognostic (2.68e-2)" "unprognostic (8.39e-2)" "unprognostic (1.12e-3)" "unprognostic (1.01e-1)" "unprognostic (9.01e-2)" "unprognostic (7.39e-2)" "unprognostic (9.31e-2)" FBXO21 "FBX21, KIAA0875" ENSG00000135108 "F-box protein 21" O94952 12 117141991-117190470 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 108.4" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 469.8;Fallopian secretory cells: 487.5;Pituicytes/FSCs: 335.1;Podocytes: 494.5;Sertoli cells: 329.5" "Cell type enhanced" "Detected in many" "Renal nephron cells: 494.5;Reproductive supporting cells: 469.8;Secretory cells: 487.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 14819418.0" "Group enriched" "Detected in some" "fallopian tube: 1206034.6;lymphoid tissue: 4211881.9" HPA071452 Approved Approved "Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 38: Non-specific - Transcription" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 12 "Centrosome, Cytosol" "Primary cilium, Primary cilium tip, Basal body" "HPA071452: " "unprognostic (2.30e-2)" "unprognostic (1.36e-2)" "unprognostic (8.39e-2)" "unprognostic (1.61e-1)" "unprognostic (1.80e-2)" "unprognostic (1.58e-2)" "unprognostic (1.58e-1)" "potential prognostic favorable (2.09e-4)" "unprognostic (2.44e-1)" "unprognostic (7.90e-2)" "validated prognostic favorable (1.36e-9)" "validated prognostic favorable (6.22e-7)" "unprognostic (1.73e-1)" "unprognostic (3.62e-1)" "unprognostic (1.96e-1)" "unprognostic (3.05e-1)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "potential prognostic favorable (2.81e-4)" "unprognostic (1.26e-1)" "unprognostic (7.66e-2)" "unprognostic (1.62e-1)" "unprognostic (8.31e-3)" "unprognostic (8.46e-2)" "unprognostic (9.26e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (9.83e-2)" "unprognostic (1.95e-1)" "unprognostic (2.74e-1)" "unprognostic (1.99e-1)" FBXO38 "Fbx38, FLJ13962, MOKA, SP329" ENSG00000145868 "F-box protein 38" Q6PIJ6 5 148383935-148442836 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 357.8" "Cell type enriched" "Detected in all" 4 "Neutrophils: 357.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1169852.2" "Group enriched" "Detected in some" "fallopian tube: 108809.9;lung: 347792.8" HPA034821 Approved Approved "Nucleoplasm,Plasma membrane,Primary cilium,Basal body" NA No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 15 "Nucleoplasm, Plasma membrane" "Primary cilium, Basal body" "HPA034821: " "unprognostic (2.16e-3)" "unprognostic (3.69e-2)" "unprognostic (6.78e-3)" "unprognostic (4.10e-3)" "unprognostic (1.07e-1)" "unprognostic (2.19e-1)" "unprognostic (7.86e-2)" "unprognostic (2.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.15e-1)" "potential prognostic favorable (1.17e-6)" "unprognostic (3.18e-2)" "unprognostic (1.25e-1)" "unprognostic (6.70e-2)" "unprognostic (4.46e-1)" "unprognostic (2.57e-2)" "unprognostic (1.10e-1)" "unprognostic (2.29e-1)" "unprognostic (3.61e-1)" "unprognostic (3.09e-2)" "unprognostic (1.02e-1)" "unprognostic (2.44e-2)" "unprognostic (2.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.88e-2)" "unprognostic (1.90e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.45e-1)" "unprognostic (2.71e-2)" "unprognostic (1.41e-1)" FBXO45 Fbx45 ENSG00000174013 "F-box protein 45" P0C2W1 3 196568611-196589059 "Predicted intracellular proteins, Predicted secreted proteins" "Neurogenesis, Ubl conjugation pathway" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 771100.9" "Tissue enhanced" "Detected in many" "intestine: 21623532.3" "HPA040730, HPA075467" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted in other tissues" "Developmental protein" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 37 "Nucleoplasm, Plasma membrane, Cytosol" Vesicles "HPA040730: , HPA075467: " "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (1.02e-1)" "unprognostic (6.75e-2)" "unprognostic (1.64e-1)" "unprognostic (3.26e-1)" "unprognostic (1.13e-1)" "unprognostic (3.35e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (2.07e-3)" "unprognostic (1.66e-1)" "unprognostic (2.67e-2)" "validated prognostic unfavorable (4.87e-4)" "validated prognostic unfavorable (4.25e-5)" "validated prognostic unfavorable (1.61e-5)" "validated prognostic unfavorable (4.27e-4)" "unprognostic (3.53e-2)" "unprognostic (1.56e-1)" "unprognostic (1.42e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-3)" "potential prognostic unfavorable (8.16e-4)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (5.82e-2)" "unprognostic (5.47e-2)" "unprognostic (9.46e-2)" "unprognostic (6.40e-2)" "unprognostic (8.14e-2)" "unprognostic (1.77e-1)" "unprognostic (3.42e-2)" FBXW11 "BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696" ENSG00000072803 "F-box and WD repeat domain containing 11" Q9UKB1 5 171861549-172006873 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 7354270.2" "Group enriched" "Detected in some" 15228 "cerebral cortex: 1623886.5;lymphoid tissue: 1421675.5" HPA072204 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 51: Secretory epithelial cells - Mixed function" 172 "Vesicles, Plasma membrane" Nucleoplasm "HPA072204: " "unprognostic (4.49e-2)" "unprognostic (2.86e-2)" "unprognostic (1.64e-1)" "unprognostic (2.90e-2)" "unprognostic (4.63e-2)" "unprognostic (3.91e-2)" "unprognostic (1.40e-1)" "unprognostic (1.07e-1)" "unprognostic (2.21e-1)" "unprognostic (7.48e-3)" "potential prognostic favorable (2.93e-9)" "unprognostic (9.18e-3)" "unprognostic (2.91e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (3.40e-1)" "unprognostic (1.18e-2)" "unprognostic (4.84e-2)" "unprognostic (3.37e-1)" "unprognostic (4.51e-2)" "potential prognostic unfavorable (3.47e-6)" "unprognostic (9.79e-2)" "unprognostic (3.47e-1)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (2.95e-1)" "unprognostic (1.14e-1)" "unprognostic (2.65e-2)" "unprognostic (2.64e-1)" "unprognostic (1.51e-2)" "unprognostic (1.77e-2)" FBXW5 "DKFZP434B205, Fbw5, MGC20962" ENSG00000159069 "F-box and WD repeat domain containing 5" Q969U6 9 136940435-136944738 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 219.8" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3413.1" "Cell type enriched" "Detected in many" 8 "Spermatogenic cell types: 3413.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 6770258.6" "Tissue enriched" "Detected in single" 6158 "lymphoid tissue: 615812.3" HPA046615 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 89 Mitochondria "HPA046615: " "unprognostic (1.16e-1)" "unprognostic (1.71e-2)" "unprognostic (3.81e-2)" "unprognostic (2.75e-3)" "unprognostic (4.08e-1)" "unprognostic (2.26e-1)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (2.69e-1)" "unprognostic (1.51e-2)" "potential prognostic favorable (1.88e-7)" "unprognostic (2.97e-1)" "unprognostic (3.45e-2)" "unprognostic (7.19e-3)" "unprognostic (1.34e-1)" "unprognostic (2.57e-2)" "unprognostic (4.63e-1)" "unprognostic (9.97e-3)" "unprognostic (2.35e-1)" "unprognostic (2.02e-1)" "unprognostic (3.43e-2)" "unprognostic (4.84e-2)" "unprognostic (1.40e-1)" "unprognostic (5.00e-2)" "unprognostic (9.20e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (6.29e-2)" "unprognostic (9.68e-2)" "unprognostic (1.20e-1)" "unprognostic (1.79e-1)" FCGBP "FC(GAMMA)BP, FcgammaBP" ENSG00000275395 "Fc gamma binding protein" 19 39863323-39934626 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 192.6;salivary gland: 87.6;thyroid gland: 93.6" "Cell type enriched" "Detected in many" 10 "Goblet cells: 10323.0" "Cell type enriched" "Detected in many" 10 "Goblet cells: 10323.0" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 76.5" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 108.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Gastric cancer: 12.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages, Skin - Langerhans cells" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 77: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: , HPA003564: " "unprognostic (6.84e-2)" "unprognostic (9.14e-3)" "unprognostic (1.46e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-3)" "unprognostic (2.16e-2)" "unprognostic (3.07e-2)" "potential prognostic favorable (1.22e-6)" "unprognostic (5.49e-3)" "unprognostic (8.03e-2)" "unprognostic (5.52e-1)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (7.45e-2)" "unprognostic (9.40e-3)" "unprognostic (2.25e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (5.05e-5)" "unprognostic (2.23e-1)" "unprognostic (9.67e-3)" "unprognostic (7.08e-3)" "unprognostic (8.98e-2)" "unprognostic (7.54e-2)" "unprognostic (1.42e-1)" "unprognostic (3.65e-1)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (1.96e-2)" FCGR2A "CD32, CD32A, CDw32, Fc-gamma-RIIa, FCG2, FcgammaRIIa, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc gamma receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.4;placenta: 126.7" "Cell type enriched" "Detected in some" 4 "Neutrophils: 452.3" "Cell type enriched" "Detected in some" 4 "Neutrophils: 452.3" "Group enriched" "Detected in some" 31 "central nervous system macrophage: 82.9;leukocyte: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2531.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 2531.1" "Cancer enriched" "Detected in some" 5 "Leukemia: 40.8" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Liver - Neutrophils, Lung - Neutrophils_2, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Thyroid gland - Macrophages" "Not detected" "Not detected" "Group enriched" "Detected in some" 20840 "bone marrow: 2126632.7;lung: 1656285.5;lymphoid tissue: 2469023.6" "HPA010718, HPA010776, HPA014730" Supported Supported "Golgi apparatus,Plasma membrane" NA NA 34000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 "Plasma membrane" "Golgi apparatus" "HPA010718: , HPA010776: , HPA014730: " "unprognostic (2.04e-1)" "unprognostic (1.41e-2)" "unprognostic (1.23e-1)" "unprognostic (5.86e-2)" "unprognostic (2.23e-1)" "unprognostic (1.57e-2)" "unprognostic (6.11e-2)" "unprognostic (5.06e-3)" "unprognostic (3.20e-2)" "unprognostic (2.79e-1)" "unprognostic (1.68e-2)" "unprognostic (2.65e-1)" "unprognostic (9.49e-2)" "unprognostic (1.31e-2)" "unprognostic (1.51e-1)" "unprognostic (8.99e-2)" "unprognostic (2.18e-3)" "unprognostic (3.85e-3)" "unprognostic (9.64e-2)" "unprognostic (1.02e-3)" "unprognostic (1.90e-2)" "unprognostic (3.68e-2)" "unprognostic (7.81e-2)" "unprognostic (1.77e-1)" "unprognostic (4.83e-3)" "unprognostic (9.63e-2)" "unprognostic (1.18e-1)" "unprognostic (2.83e-2)" "unprognostic (2.36e-2)" "unprognostic (1.91e-1)" "unprognostic (4.06e-1)" FCGR2C "CD32C, Fc-gamma-RIIc, FcgammaRIIc, hFcRII-C" ENSG00000244682 "Fc gamma receptor IIc (gene/pseudogene)" 1 161581339-161605662 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 11 "placenta: 26.6" "Group enriched" "Detected in some" 5 "cDC: 22.8;Macrophages: 28.6;Microglia: 13.2;monocytes: 15.5" "Group enriched" "Detected in some" 5 "dendritic cells: 22.8;Glial cells: 13.2;Mononuclear phagocytes: 28.6" "Group enriched" "Detected in some" 23 "central nervous system macrophage: 37.4;leukocyte: 23.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 7.4" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Leukemia: 1.4" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Skeletal muscle - Macrophages" "HPA010718, HPA010776, HPA014730" Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" "Plasma membrane" "Golgi apparatus" "HPA010718: , HPA010776: , HPA014730: " FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1232.7;Microglia: 1168.0;Neutrophils: 884.3;pDCs: 2334.7" "Cell type enhanced" "Detected in all" "dendritic cells: 2334.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1570.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 4331662.5;Macrophages: 4663895.2" "Tissue enhanced" "Detected in many" "bone marrow: 6438822.4;lymphoid tissue: 4572247.2" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 32: Basophils - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 11 "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: , HPA038546: " "unprognostic (1.76e-3)" "unprognostic (4.06e-1)" "unprognostic (6.82e-2)" "unprognostic (4.10e-2)" "unprognostic (3.97e-1)" "unprognostic (3.36e-1)" "unprognostic (7.84e-2)" "unprognostic (8.27e-3)" "potential prognostic favorable (3.74e-4)" "unprognostic (2.22e-2)" "potential prognostic favorable (3.15e-5)" "unprognostic (4.52e-2)" "unprognostic (8.58e-2)" "unprognostic (3.69e-2)" "unprognostic (1.32e-2)" "unprognostic (2.17e-2)" "unprognostic (5.58e-2)" "unprognostic (5.80e-2)" "unprognostic (3.00e-1)" "unprognostic (7.84e-2)" "unprognostic (6.35e-2)" "unprognostic (3.19e-2)" "unprognostic (6.21e-3)" "unprognostic (8.92e-2)" "unprognostic (2.19e-2)" "unprognostic (1.72e-2)" "unprognostic (5.51e-3)" "unprognostic (5.12e-2)" "unprognostic (1.73e-1)" "unprognostic (5.27e-2)" "unprognostic (2.35e-1)" FCSK "FLJ39408, FUK" ENSG00000157353 "Fucose kinase" Q8N0W3 16 70454595-70480274 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 38.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "Stomach: 25248866.9" HPA041971 Approved Approved Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 25: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 Vesicles "HPA041971: " "unprognostic (1.01e-1)" "unprognostic (1.81e-1)" "unprognostic (1.43e-2)" "unprognostic (9.07e-2)" "unprognostic (1.24e-1)" "unprognostic (2.06e-2)" "unprognostic (4.33e-2)" "unprognostic (4.23e-3)" "unprognostic (4.80e-3)" "potential prognostic favorable (1.60e-6)" "unprognostic (7.64e-2)" "potential prognostic favorable (2.10e-5)" "unprognostic (1.13e-2)" "unprognostic (3.58e-2)" "unprognostic (1.73e-1)" "unprognostic (1.87e-2)" "unprognostic (1.40e-1)" "unprognostic (1.04e-1)" "unprognostic (6.03e-2)" "unprognostic (1.72e-1)" "unprognostic (1.80e-1)" "unprognostic (4.85e-2)" "unprognostic (2.57e-2)" "unprognostic (3.48e-2)" "unprognostic (2.99e-1)" "unprognostic (3.50e-2)" "unprognostic (1.75e-1)" "unprognostic (2.40e-1)" "unprognostic (2.11e-1)" FDPS ENSG00000160752 "Farnesyl diphosphate synthase" P14324 1 155308748-155320666 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Host-virus interaction, Isoprene biosynthesis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 332.6" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 465.5;Breast lactating cells: 497.3;Colonocytes: 712.8;Epididymal principal cells: 806.1;Esophageal apical cells: 653.7;Esophageal suprabasal cells: 535.2" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 806.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 71098066.2" "Tissue enhanced" "Detected in all" "liver: 121673157.3" HPA028200 Approved Approved Nucleoplasm,Cytosol NA NA 3900000 "Cluster 25: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 22 Cytosol Nucleoplasm "HPA028200: " "unprognostic (3.56e-2)" "unprognostic (1.95e-1)" "unprognostic (2.29e-2)" "unprognostic (2.27e-2)" "unprognostic (1.13e-1)" "unprognostic (1.68e-1)" "unprognostic (4.76e-2)" "unprognostic (8.31e-3)" "unprognostic (2.24e-2)" "unprognostic (6.62e-2)" "potential prognostic favorable (2.24e-6)" "unprognostic (3.22e-3)" "unprognostic (1.94e-1)" "unprognostic (1.47e-3)" "unprognostic (1.35e-3)" "unprognostic (1.41e-2)" "unprognostic (2.18e-2)" "unprognostic (1.98e-1)" "unprognostic (1.87e-1)" "unprognostic (1.81e-2)" "unprognostic (2.16e-1)" "unprognostic (6.36e-2)" "unprognostic (3.88e-1)" "unprognostic (6.98e-2)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "unprognostic (4.03e-1)" "unprognostic (2.11e-1)" "unprognostic (4.39e-1)" "unprognostic (2.96e-2)" FDX1 "ADX, FDX" ENSG00000137714 "Ferredoxin 1" P10109 11 110429948-110464884 "Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Steroidogenesis, Sterol metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "adrenal gland: 300.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1824.0;Mast cells: 405.8;Syncytiotrophoblasts: 1367.3" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 1824.0;Trophoblast cells: 1367.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 5743749.4" "Tissue enhanced" "Detected in all" "liver: 132728141.9" "HPA041630, HPA062087" Enhanced Enhanced Mitochondria NA NA 6100 "Cluster 3: Non-specific - Nuclear processes" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Mitochondria "HPA041630: , HPA062087: " "unprognostic (3.73e-1)" "unprognostic (9.50e-2)" "unprognostic (3.36e-2)" "unprognostic (4.30e-2)" "unprognostic (1.27e-2)" "unprognostic (1.95e-1)" "unprognostic (2.80e-1)" "unprognostic (2.79e-1)" "unprognostic (3.50e-3)" "unprognostic (1.14e-1)" "potential prognostic favorable (4.74e-8)" "unprognostic (2.56e-3)" "unprognostic (1.41e-2)" "unprognostic (1.03e-2)" "potential prognostic favorable (1.64e-5)" "unprognostic (8.33e-2)" "unprognostic (1.30e-1)" "unprognostic (4.81e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (8.80e-2)" "unprognostic (7.55e-2)" "unprognostic (3.28e-1)" "unprognostic (1.72e-1)" "unprognostic (3.59e-2)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (1.64e-1)" "unprognostic (1.54e-1)" "unprognostic (8.04e-2)" "unprognostic (4.44e-2)" FDXR "ADR, ADXR" ENSG00000161513 "Ferredoxin reductase" P22570 17 74862497-74873031 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol metabolism, Electron transport, Lipid metabolism, Steroid metabolism, Sterol metabolism, Transport" Oxidoreductase "Deafness, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "adrenal gland: 339.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 90.5;Cytotrophoblasts: 65.0;Esophageal basal cells: 82.7;Esophageal suprabasal cells: 90.6;Fallopian tube ciliated cells: 95.3;Granulosa cells: 207.6;Respiratory ciliated cells: 83.7;Sertoli cells: 70.7" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 207.6" "Cell type enhanced" "Detected in all" "ependymal cell: 24.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Granulosa cells: 451812038.8;Oocytes: 251335204.3" "Low tissue specificity" "Detected in all" "CAB008597, CAB009818, HPA044393, HPA053673" Enhanced Enhanced Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Mitochondria "CAB008597: , CAB009818: , HPA044393: , HPA053673: " "unprognostic (1.10e-1)" "unprognostic (2.84e-1)" "unprognostic (2.19e-1)" "unprognostic (5.26e-2)" "unprognostic (3.63e-3)" "unprognostic (3.48e-2)" "unprognostic (6.42e-2)" "unprognostic (4.65e-2)" "unprognostic (3.61e-2)" "unprognostic (1.15e-1)" "unprognostic (2.10e-3)" "unprognostic (5.67e-3)" "unprognostic (4.19e-3)" "unprognostic (1.58e-1)" "unprognostic (9.88e-2)" "unprognostic (3.48e-1)" "unprognostic (6.17e-2)" "unprognostic (1.47e-1)" "unprognostic (2.58e-2)" "unprognostic (2.69e-1)" "unprognostic (9.67e-2)" "unprognostic (1.27e-1)" "unprognostic (2.59e-1)" "unprognostic (2.36e-1)" "unprognostic (1.45e-1)" "unprognostic (1.20e-1)" "unprognostic (3.51e-1)" "unprognostic (3.69e-2)" "unprognostic (1.83e-1)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" FER "PPP1R74, TYK3" ENSG00000151422 "FER tyrosine kinase" P16591 5 108747841-109196841 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 2092.3" "Cell type enhanced" "Detected in all" "Mast cells: 2092.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 353031.0" "Tissue enriched" "Detected in some" "bone marrow: 3789398.2" "HPA007641, CAB022464" Approved Supported Cytosol NA NA "Cluster 61: Non-specific - Transcription" "Cluster 22: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 58: Mast cells - Allergic inflammatory responses" 13 Cytosol "CAB022464: , HPA007641: " "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.41e-1)" "unprognostic (8.40e-3)" "unprognostic (2.19e-1)" "unprognostic (1.75e-1)" "unprognostic (2.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.51e-1)" "unprognostic (7.37e-3)" "potential prognostic favorable (5.39e-5)" "unprognostic (1.40e-3)" "unprognostic (2.12e-1)" "unprognostic (1.84e-2)" "unprognostic (1.54e-2)" "unprognostic (3.10e-2)" "unprognostic (3.21e-2)" "unprognostic (2.85e-2)" "unprognostic (1.75e-1)" "unprognostic (4.73e-2)" "unprognostic (4.30e-2)" "unprognostic (3.20e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (2.49e-1)" "unprognostic (1.60e-1)" "unprognostic (4.63e-2)" "unprognostic (2.22e-1)" "unprognostic (2.60e-2)" "unprognostic (1.69e-1)" "unprognostic (3.39e-2)" "unprognostic (1.33e-1)" FER1L6 C8ORFK23 ENSG00000214814 "Fer-1 like family member 6" Q2WGJ9 8 123851987-124120061 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "stomach 1: 40.7" "Group enriched" "Detected in many" 6 "Foveolar cells: 1012.8;Goblet cells: 1164.9" "Group enriched" "Detected in many" 6 "Gastric glandular cells: 1012.8;Goblet cells: 1164.9" "Cell type enriched" "Detected in many" 5 "deep-layer near-projecting: 38.6" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 5.9;Stomach Adenocarcinoma (TCGA): 7.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.5;pancreatic cancer: 2.0" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 655 "intestine: 65460.4" HPA054117 Enhanced Approved "Plasma membrane,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 17: Intestine - Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" "Plasma membrane" "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA054117: " "unprognostic (3.25e-3)" "unprognostic (6.26e-2)" "unprognostic (1.42e-1)" "unprognostic (2.09e-2)" "unprognostic (6.92e-2)" "unprognostic (2.57e-1)" "unprognostic (1.60e-2)" "unprognostic (1.70e-2)" "unprognostic (4.78e-3)" "unprognostic (2.14e-2)" "unprognostic (6.31e-2)" FERMT2 "KIND2, mig-2, PLEKHC1, UNC112B" ENSG00000073712 "FERM domain containing kindlin 2" Q96AC1 14 52857268-52952435 "Predicted intracellular proteins" "Cell adhesion, Cell shape, Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 419.6;Podocytes: 360.0;Smooth muscle cells: 536.9" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 536.9" "Cell type enhanced" "Detected in all" "pericyte: 324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 231983704.3;Smooth muscle cells: 209687601.9" "Low tissue specificity" "Detected in all" "HPA040505, HPA072965" Uncertain Supported "Nucleoplasm,Focal adhesion sites,Cytosol" NA NA 81000 "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 19 "Focal adhesion sites" "Nucleoplasm, Cytosol" "HPA040505: , HPA072965: " "unprognostic (1.29e-1)" "unprognostic (2.93e-2)" "unprognostic (2.46e-1)" "unprognostic (1.72e-1)" "unprognostic (1.18e-2)" "unprognostic (6.62e-2)" "unprognostic (2.91e-2)" "unprognostic (2.50e-2)" "unprognostic (6.94e-3)" "unprognostic (2.65e-2)" "potential prognostic favorable (1.23e-5)" "unprognostic (1.94e-2)" "unprognostic (4.47e-2)" "unprognostic (7.13e-2)" "unprognostic (7.24e-2)" "unprognostic (5.23e-2)" "unprognostic (2.68e-2)" "unprognostic (8.90e-2)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (7.09e-3)" "unprognostic (2.08e-1)" "unprognostic (1.52e-1)" "unprognostic (2.13e-1)" "unprognostic (2.31e-2)" "unprognostic (2.66e-2)" "unprognostic (4.23e-2)" "unprognostic (3.60e-3)" "unprognostic (1.52e-1)" "unprognostic (8.86e-2)" "unprognostic (2.13e-2)" FERMT3 "KIND3, MGC10966, MIG2B, UNC112C, URP2" ENSG00000149781 "FERM domain containing kindlin 3" Q86UX7 11 64205926-64223896 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.6;lymphoid tissue: 125.3" "Group enriched" "Detected in many" 6 "Megakaryocytes: 2225.4;Platelets: 2366.1" "Group enriched" "Detected in many" 9 "Megakaryocytes: 2225.4;Platelets: 2366.1" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 28.9;leukocyte: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 126.8;lymphoma: 93.3;Myeloma: 55.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Pituitary gland - Macrophages, Skeletal muscle - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "B-cells: 195711621.7;Macrophages: 438989239.6;Neutrophils: 222627744.8;T-cells: 241020496.5" "Group enriched" "Detected in all" "bone marrow: 208986535.0;lymphoid tissue: 302252515.8" HPA065231 Approved Vesicles NA NA 200000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 47: Platelets - Hemostasis" 1 Vesicles "HPA065231: " "unprognostic (1.58e-2)" "unprognostic (8.96e-3)" "unprognostic (1.47e-2)" "potential prognostic favorable (7.89e-4)" "unprognostic (3.41e-2)" "unprognostic (1.02e-1)" "unprognostic (1.18e-2)" "unprognostic (1.51e-1)" "unprognostic (1.38e-2)" "unprognostic (3.49e-1)" "unprognostic (2.83e-3)" "unprognostic (3.44e-1)" "unprognostic (1.47e-1)" "unprognostic (2.57e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.51e-1)" "unprognostic (9.66e-2)" "unprognostic (2.74e-1)" "unprognostic (4.17e-1)" "unprognostic (1.57e-2)" "unprognostic (2.31e-1)" "unprognostic (1.67e-3)" "unprognostic (3.19e-1)" "unprognostic (2.46e-1)" "unprognostic (1.54e-1)" "unprognostic (5.05e-2)" "unprognostic (9.70e-3)" "unprognostic (3.13e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-2)" FETUB ENSG00000090512 "Fetuin B" Q9UGM5 3 186635969-186653141 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "liver: 219.3" "Group enriched" "Detected in some" 6 "Esophageal apical cells: 70.4;Hepatocytes: 55.6" "Group enriched" "Detected in some" 6 "Apical squamous epithelial cells: 70.4;Hepatocytes: 55.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Liver Hepatocellular Carcinoma (TCGA): 44.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Alveolar cell types: 234308.2" "Low tissue specificity" "Detected in many" "HPA035132, HPA035133" Supported Approved Vesicles "Secreted to blood" "Enzyme inhibitor" NA NA 47500000000 2500000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 Vesicles "HPA035132: , HPA035133: " "unprognostic (1.21e-2)" "unprognostic (2.01e-1)" "unprognostic (1.79e-2)" "unprognostic (6.27e-3)" "unprognostic (5.14e-3)" "unprognostic (2.15e-1)" FEZF1 ZNF312B ENSG00000128610 "FEZ family zinc finger 1" A0PJY2 7 122301303-122310691 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 13.1;pituitary gland: 3.0;testis: 4.2" "Cell type enhanced" "Detected in some" "Gastric progenitor cells: 35.9;Late primary spermatocytes: 20.1;Oocytes: 4.6;Other brain neurons: 3.4;Pituicytes/FSCs: 9.2;Retinal bipolar cells: 6.3" "Cell type enhanced" "Detected in some" "Glial cells: 9.2;Proliferating cells: 35.9;Spermatogenic cell types: 20.1" "Cell type enhanced" "Detected in some" "amygdala excitatory: 1.4;astrocyte: 1.8;ependymal cell: 1.4;splatter: 1.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 38 "hypothalamus: 270.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Bone cancer: 53.3" "Testis - Early spermatids" "Region enriched" "Detected in some" 11 "hypothalamus: 11.7" "Region enriched" "Detected in single" 14 "hypothalamus: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA064639, HPA073693" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 6 Nucleoplasm Cytosol "HPA064639: , HPA073693: " "unprognostic (1.59e-1)" "unprognostic (4.37e-2)" "unprognostic (1.79e-1)" "unprognostic (1.58e-3)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (3.95e-5)" "unprognostic (3.36e-1)" "unprognostic (1.80e-1)" "unprognostic (6.46e-3)" "unprognostic (2.24e-3)" "potential prognostic favorable (2.44e-4)" "unprognostic (2.44e-1)" "unprognostic (3.74e-3)" "unprognostic (2.35e-1)" "unprognostic (6.66e-3)" "unprognostic (1.27e-1)" FGA ENSG00000171560 "Fibrinogen alpha chain" P02671 4 154583126-154590742 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Amyloidosis, Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 384 "liver: 17201.5" "Cell type enriched" "Detected in some" 44 "Hepatocytes: 17123.8" "Cell type enriched" "Detected in many" 44 "Hepatocytes: 17123.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 21 "Liver Hepatocellular Carcinoma (TCGA): 5313.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "liver cancer: 180.5" "Liver - Hepatocytes, Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Cell type enhanced" "Detected in all" "Alveolar cell types: 801939120.1" "Low tissue specificity" "Detected in all" "CAB016776, HPA051370, HPA064755" Supported Enhanced "Endoplasmic reticulum" "Secreted to blood" "Blood coagulation" NA NA 407000000 210000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 15 "Endoplasmic reticulum" "CAB016776: , HPA051370: , HPA064755: " "unprognostic (1.36e-1)" "unprognostic (4.10e-2)" "unprognostic (5.40e-2)" "unprognostic (2.33e-2)" "unprognostic (1.65e-2)" "unprognostic (1.41e-3)" "unprognostic (1.26e-3)" "unprognostic (2.52e-2)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (3.10e-5)" "unprognostic (2.81e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (7.62e-6)" "unprognostic (7.32e-2)" "unprognostic (3.70e-1)" "unprognostic (2.73e-1)" "unprognostic (1.16e-1)" "unprognostic (4.56e-1)" FGB ENSG00000171564 "Fibrinogen beta chain" P02675 4 154563011-154572807 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Blood coagulation, Hemostasis, Immunity, Innate immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 351 "liver: 16764.8" "Cell type enriched" "Detected in some" 76 "Hepatocytes: 17547.8" "Cell type enriched" "Detected in some" 76 "Hepatocytes: 17547.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 21 "Liver Hepatocellular Carcinoma (TCGA): 4509.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "liver cancer: 219.4" "Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cell types: 1007453719.5" "Tissue enhanced" "Detected in all" "lung: 1622998842.3" "HPA001900, HPA001901, CAB008624" Enhanced Enhanced "Endoplasmic reticulum" "Secreted to blood" "Blood coagulation" NA NA 170000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 24 "Endoplasmic reticulum" "CAB008624: , HPA001900: , HPA001901: " "unprognostic (1.05e-3)" "unprognostic (8.75e-2)" "unprognostic (1.35e-2)" "unprognostic (1.84e-2)" "unprognostic (3.73e-3)" "unprognostic (1.02e-1)" "unprognostic (4.31e-2)" "unprognostic (4.17e-2)" "unprognostic (7.12e-3)" "potential prognostic favorable (7.15e-4)" "unprognostic (7.37e-3)" "unprognostic (1.02e-1)" "unprognostic (2.83e-1)" "unprognostic (8.27e-2)" "potential prognostic unfavorable (3.44e-9)" "unprognostic (1.46e-1)" "unprognostic (3.78e-1)" "unprognostic (2.40e-2)" "unprognostic (9.50e-2)" "unprognostic (1.01e-1)" FGD4 "CMT4H, frabin, FRABP, ZFYVE6" ENSG00000139132 "FYVE, RhoGEF and PH domain containing 4" Q96M96 12 32399558-32646050 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Guanine-nucleotide releasing factor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 1393.7;Neutrophil progenitors: 1727.6;Neutrophils: 4466.3;Rod photoreceptor cells: 1140.4" "Cell type enhanced" "Detected in many" "Neutrophils: 4466.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1071.7" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 35.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 3.5;eosinophil: 8.2;intermediate monocyte: 5.8;myeloid DC: 3.4;neutrophil: 5.2;non-classical monocyte: 5.2" "Group enriched" "Detected in many" 6 "dendritic cells: 3.4;granulocytes: 8.2;monocytes: 5.8" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA039235 Approved Approved "Actin filaments" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" "Actin filaments" "HPA039235: " "unprognostic (5.62e-2)" "unprognostic (4.61e-2)" "unprognostic (6.23e-2)" "unprognostic (1.81e-3)" "unprognostic (2.65e-2)" "unprognostic (3.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-2)" "unprognostic (3.60e-3)" "potential prognostic favorable (1.16e-4)" "unprognostic (6.96e-2)" "unprognostic (1.60e-1)" "unprognostic (6.19e-3)" "potential prognostic favorable (8.05e-4)" "unprognostic (1.04e-1)" "unprognostic (2.16e-1)" "unprognostic (5.78e-3)" "unprognostic (4.17e-3)" "unprognostic (8.45e-2)" "unprognostic (1.61e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (8.65e-2)" "unprognostic (4.24e-2)" "unprognostic (7.17e-2)" "unprognostic (1.34e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (1.12e-1)" "unprognostic (3.60e-2)" FGFR1 "BFGFR, CD331, CEK, FLG, FLT2, H2, H3, H4, H5, KAL2, N-SAM" ENSG00000077782 "Fibroblast growth factor receptor 1" P11362 8 38400215-38468834 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Transcription, Transcription regulation" "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Dwarfism, FDA approved drug targets, Holoprosencephaly, Hypogonadotropic hypogonadism, Intellectual disability, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 302.0;Fibro-adipogenic progenitors: 280.7;Fibroblasts: 375.3;Leydig cells: 296.1;Pancreatic acinar cells: 541.7;Salivary myoepithelial cells: 296.6;Smooth muscle cells: 279.1" "Cell type enhanced" "Detected in many" "Acinar cells: 541.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "Rhabdoid: 200.8" "Breast - Fibroblasts, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" "intestine: 172623.7;ovary: 284828.1" "HPA009029, CAB033614, HPA056402" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body,Cytosol" Yes NA 13000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 93 "Microtubules, Cytokinetic bridge, Mitotic spindle" "Primary cilium, Centriolar satellite, Basal body, Cytosol" "CAB033614: , HPA009029: , HPA056402: " "unprognostic (1.44e-1)" "unprognostic (7.85e-2)" "unprognostic (2.49e-1)" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (6.62e-2)" "unprognostic (1.11e-2)" "unprognostic (3.70e-3)" "unprognostic (1.33e-1)" "unprognostic (2.20e-1)" "unprognostic (1.00e-2)" "unprognostic (4.48e-3)" "unprognostic (5.05e-2)" "unprognostic (2.58e-1)" "unprognostic (5.19e-2)" "unprognostic (5.23e-2)" "unprognostic (2.72e-1)" "unprognostic (1.08e-1)" "unprognostic (4.90e-2)" "unprognostic (1.16e-1)" "unprognostic (4.08e-2)" "unprognostic (3.39e-2)" "unprognostic (5.52e-2)" "unprognostic (4.75e-2)" "unprognostic (1.02e-1)" "unprognostic (5.74e-2)" "unprognostic (1.83e-1)" "unprognostic (4.24e-3)" "unprognostic (8.84e-2)" "unprognostic (9.56e-3)" "unprognostic (8.24e-2)" FGG ENSG00000171557 "Fibrinogen gamma chain" P02679 4 154604134-154612967 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Blood coagulation, Hemostasis" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 327 "liver: 15475.1" "Cell type enriched" "Detected in some" 13 "Hepatocytes: 8736.4" "Cell type enriched" "Detected in many" 13 "Hepatocytes: 8736.4" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 9 "Liver Hepatocellular Carcinoma (TCGA): 4055.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "liver cancer: 229.6" "Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in all" "Alveolar cell types: 1063048153.3" "Tissue enhanced" "Detected in all" "lung: 1539572995.2" "HPA011159, HPA027529, CAB033120, HPA074638" Supported Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" "Blood coagulation" NA NA 267000000000 130000000000 "Cluster 53: Liver - Plasma proteins" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 "Endoplasmic reticulum" Vesicles "CAB033120: , HPA011159: , HPA027529: , HPA074638: " "unprognostic (2.72e-2)" "unprognostic (3.50e-2)" "unprognostic (2.97e-1)" "unprognostic (6.99e-2)" "unprognostic (6.67e-2)" "unprognostic (4.64e-3)" "unprognostic (9.60e-2)" "unprognostic (5.43e-3)" "unprognostic (2.77e-2)" "unprognostic (3.65e-2)" "unprognostic (3.67e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (2.58e-1)" "unprognostic (8.80e-3)" "potential prognostic unfavorable (3.59e-5)" "unprognostic (3.39e-3)" "unprognostic (3.28e-1)" FGGY FLJ10986 ENSG00000172456 "FGGY carbohydrate kinase domain containing" Q96C11 1 59296638-59810647 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 70.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 495.6;Myonuclei: 526.5;Proximal tubule cells: 778.6;Thymic myoid cells: 806.3" "Cell type enhanced" "Detected in all" "Renal nephron cells: 778.6;Stromal cells: 806.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 99.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 30416330.2;Proximal tubules: 17541735.6" "Group enriched" "Detected in all" "liver: 15585565.1;lymphoid tissue: 16571635.5" "HPA054971, HPA075137" Approved "Nucleoplasm,Nuclear bodies" NA NA 95000 "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 Nucleoplasm "Nuclear bodies" "HPA054971: , HPA075137: " "unprognostic (3.84e-1)" "unprognostic (8.80e-2)" "unprognostic (2.44e-1)" "unprognostic (2.17e-1)" "unprognostic (3.91e-1)" "unprognostic (9.12e-2)" "unprognostic (1.48e-1)" "unprognostic (1.92e-1)" "unprognostic (3.73e-3)" "unprognostic (2.96e-1)" "validated prognostic favorable (2.00e-6)" "validated prognostic favorable (2.57e-4)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.63e-3)" "potential prognostic favorable (5.33e-4)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.57e-1)" "unprognostic (1.64e-2)" "unprognostic (3.44e-1)" "unprognostic (8.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.07e-1)" "unprognostic (1.46e-1)" "unprognostic (2.59e-1)" "unprognostic (6.07e-2)" "unprognostic (4.17e-1)" "unprognostic (9.15e-2)" "unprognostic (1.72e-1)" "unprognostic (1.62e-1)" "unprognostic (1.49e-1)" FHDC1 "INF1, KIAA1727" ENSG00000137460 "FH2 domain containing 1" Q9C0D6 4 152936323-152979671 "Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 16.5;thyroid gland: 14.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 110.6;Prostatic glandular cells: 54.8;Syncytiotrophoblasts: 196.3" "Cell type enhanced" "Detected in many" "Alveolar cells: 110.6;Trophoblast cells: 196.3" "Cell type enhanced" "Detected in many" "medium spiny neuron: 39.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8327 "Alveolar cell types: 1001591.0;Granulosa cells: 663816.6" "Tissue enriched" "Detected in some" "pancreas: 3348971.7" "HPA008527, HPA008603" Uncertain Uncertain "Primary cilium,Centrosome,Basal body" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Centrosome, Basal body" "Primary cilium" "HPA008527: , HPA008603: " "unprognostic (8.66e-2)" "unprognostic (3.64e-2)" "unprognostic (3.23e-1)" "unprognostic (1.52e-1)" "unprognostic (1.41e-2)" "unprognostic (5.13e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.06e-4)" "unprognostic (2.63e-1)" "unprognostic (2.10e-1)" "unprognostic (1.94e-1)" "unprognostic (6.97e-2)" "unprognostic (1.09e-2)" "unprognostic (3.96e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.93e-1)" "unprognostic (3.36e-1)" "unprognostic (8.07e-3)" "unprognostic (2.22e-2)" "unprognostic (6.18e-2)" "unprognostic (1.64e-1)" "unprognostic (3.69e-2)" "unprognostic (5.35e-2)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (2.75e-1)" "unprognostic (5.89e-2)" "unprognostic (1.10e-1)" FHL2 "DRAL, SLIM3" ENSG00000115641 "Four and a half LIM domains 2" Q14192 2 105357712-105438513 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 8 "heart muscle: 1337.6;ovary: 513.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 3363.2;Epididymal efferent duct ciliated cells: 632.9;Extravillous trophoblasts: 1005.1;Leydig cells: 746.3;Migrating cytotrophoblasts: 601.0;Ovarian stromal cells: 1038.6;Peritubular myoid cells: 1236.9" "Cell type enhanced" "Detected in all" "Myocytes: 3363.2;Stromal cells: 1236.9" "Cell type enhanced" "Detected in many" "fibroblast: 320.3;hippocampal dentate gyrus: 118.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 5.1" "Group enriched" "Detected in many" 6 "granulocytes: 5.1;T-cells: 2.6" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Capillaries: 202850409.6;Cardiomyocytes: 330981931.5" "Tissue enriched" "Detected in many" "heart muscle: 71028590.0" "HPA005922, HPA006028, CAB008368" Enhanced Enhanced "Actin filaments,Focal adhesion sites" NA Yes 4000 "Cluster 35: Neutrophils - Protein binding" "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 193 "Actin filaments, Focal adhesion sites" "CAB008368: , HPA005922: , HPA006028: " "unprognostic (4.40e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (8.08e-3)" "unprognostic (3.14e-1)" "unprognostic (8.15e-2)" "unprognostic (4.63e-2)" "unprognostic (4.30e-3)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (7.89e-2)" "unprognostic (9.56e-3)" "unprognostic (5.77e-2)" "unprognostic (1.61e-1)" "unprognostic (6.61e-2)" "unprognostic (5.29e-3)" "unprognostic (4.77e-3)" "potential prognostic unfavorable (8.24e-6)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (1.62e-2)" "unprognostic (9.21e-2)" "unprognostic (1.25e-2)" "unprognostic (5.25e-2)" "unprognostic (2.77e-2)" "unprognostic (2.38e-1)" "unprognostic (3.13e-1)" "unprognostic (2.49e-1)" "unprognostic (8.03e-2)" "unprognostic (5.00e-2)" "unprognostic (1.87e-3)" "unprognostic (3.35e-1)" FIG4 "ALS11, CMT4J, dJ249I4.1, hSac3, KIAA0274, SAC3" ENSG00000112367 "FIG4 phosphoinositide 5-phosphatase" Q92562 6 109690609-109878098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 119.3;Neutrophil progenitors: 150.5" "Cell type enhanced" "Detected in many" "Neutrophils: 150.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" "fallopian tube: 1211060.5;intestine: 1446404.1;lymphoid tissue: 3327693.1;Stomach: 4317940.9" "CAB017823, HPA068859" Approved Supported "Vesicles,Lipid droplets" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 11 "Vesicles, Lipid droplets" "CAB017823: , HPA068859: " "unprognostic (2.98e-1)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (1.07e-2)" "unprognostic (1.80e-2)" "unprognostic (2.89e-2)" "unprognostic (3.20e-1)" "unprognostic (6.84e-2)" "unprognostic (1.33e-2)" "unprognostic (7.91e-2)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.90e-8)" "unprognostic (1.66e-2)" "unprognostic (8.73e-2)" "unprognostic (2.19e-2)" "unprognostic (5.05e-2)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (4.63e-2)" "unprognostic (4.12e-1)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (7.49e-2)" "unprognostic (2.32e-1)" "unprognostic (1.92e-1)" "unprognostic (9.44e-3)" "unprognostic (1.62e-1)" "unprognostic (4.01e-3)" "unprognostic (3.29e-1)" "unprognostic (1.77e-1)" "unprognostic (2.51e-1)" "unprognostic (3.08e-2)" FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 50.3;skeletal muscle: 33.8;tongue: 45.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 196.7;Cardiomyocytes: 728.4;Corticotrophs: 340.6;Fibro-adipogenic progenitors: 226.6;Myonuclei: 1223.6;Respiratory ciliated cells: 213.5;Smooth muscle cells: 653.5;Thymic myoid cells: 732.8;Vascular smooth muscle cells: 319.3" "Cell type enhanced" "Detected in many" "Myocytes: 1223.6;Smooth muscle cells: 653.5;Stromal cells: 732.8" "Cell type enriched" "Detected in all" 6 "vascular associated smooth muscle cell: 405.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "ovarian cancer: 3.0" "Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Alveolar cell types: 4734421.7;Capillaries: 3218375.6;Cardiomyocytes: 6118312.1;Skeletal myofibers: 5310670.8;Smooth muscle cells: 2261629.2" "Tissue enriched" "Detected in many" "skeletal muscle: 23245721.5" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 3 "Plasma membrane, Actin filaments" "HPA053564: " "unprognostic (1.01e-2)" "unprognostic (1.16e-1)" "unprognostic (2.34e-1)" "unprognostic (2.01e-2)" "unprognostic (2.21e-1)" "unprognostic (4.71e-1)" "unprognostic (7.17e-2)" "potential prognostic favorable (6.95e-6)" "unprognostic (1.47e-3)" "unprognostic (1.17e-2)" "unprognostic (7.89e-2)" "unprognostic (6.13e-2)" "unprognostic (1.02e-2)" "unprognostic (4.39e-2)" "unprognostic (2.46e-2)" "unprognostic (7.26e-2)" "unprognostic (2.86e-1)" "unprognostic (9.91e-2)" "unprognostic (1.08e-1)" "unprognostic (1.11e-2)" "unprognostic (1.78e-1)" "unprognostic (2.57e-2)" FKBP1A "FKBP-12, FKBP1, FKBP12, FKBP12C, PKC12, PPIASE" ENSG00000088832 "FKBP prolyl isomerase 1A" P62942 20 1368977-1393164 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Isomerase, Rotamase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 37.0;Extravillous trophoblasts: 27.5;Hofbauer cells: 24.7;Late primary spermatocytes: 25.6;Late spermatids: 30.3;Megakaryocytes: 30.9;Platelets: 33.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 37.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 675.8;granulocytes: 976.4;monocytes: 1017.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 62697813.1" "Low tissue specificity" "Detected in all" "CAB004639, HPA051330, HPA051798" Uncertain Approved "Golgi apparatus,Primary cilium,Basal body,Cytosol" NA NA 19000000 "Cluster 29: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 33: Neurons - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 23 "Golgi apparatus" "Primary cilium, Basal body, Cytosol" "CAB004639: , HPA051330: , HPA051798: " "unprognostic (1.31e-2)" "unprognostic (1.54e-2)" "unprognostic (2.47e-1)" "unprognostic (2.92e-1)" "unprognostic (8.04e-2)" "unprognostic (2.29e-2)" "unprognostic (4.89e-1)" "unprognostic (3.60e-3)" "unprognostic (1.93e-3)" "unprognostic (5.14e-2)" "potential prognostic favorable (2.11e-6)" "unprognostic (3.29e-2)" "unprognostic (7.51e-2)" "validated prognostic unfavorable (2.53e-7)" "validated prognostic unfavorable (7.09e-5)" "unprognostic (3.28e-2)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (1.91e-4)" "unprognostic (7.72e-3)" "unprognostic (1.51e-1)" "unprognostic (3.94e-1)" "unprognostic (5.54e-3)" "unprognostic (1.46e-2)" "unprognostic (3.20e-1)" "unprognostic (1.25e-1)" "unprognostic (4.94e-2)" "unprognostic (1.38e-1)" "unprognostic (9.61e-3)" "unprognostic (2.42e-1)" "unprognostic (2.77e-2)" "unprognostic (1.47e-1)" FKBP1B "FKBP12.6, FKBP1L, FKBP9, OTK4, PPIase" ENSG00000119782 "FKBP prolyl isomerase 1B" P68106 2 24049701-24063681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 73.7" "Group enriched" "Detected in many" 5 "Megakaryocytes: 383.3;Platelets: 129.2" "Group enriched" "Detected in many" 5 "Megakaryocytes: 383.3;Platelets: 129.2" "Cell type enhanced" "Detected in all" "hippocampal CA4: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 2.2;T-reg: 2.8" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "testis cancer: 42.5" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 158263.6;Microglia and Neuropil: 577251.3;Neurons: 230118.4" "Group enriched" "Detected in many" "bone marrow: 2708293.5;cerebral cortex: 1756855.7" "HPA045572, HPA051330, HPA051798" Uncertain Approved "Golgi apparatus,Vesicles,Primary cilium,Basal body,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 47: Platelets - Hemostasis" 9 "Golgi apparatus, Vesicles" "Primary cilium, Basal body, Cytosol" "HPA045572: , HPA051330: , HPA051798: " "unprognostic (2.51e-2)" "unprognostic (2.96e-2)" "unprognostic (3.89e-1)" "unprognostic (1.65e-1)" "unprognostic (1.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-2)" "unprognostic (8.43e-3)" "unprognostic (1.90e-1)" "unprognostic (4.20e-1)" "unprognostic (7.61e-3)" "unprognostic (1.74e-2)" "unprognostic (1.84e-2)" "unprognostic (7.21e-3)" "unprognostic (2.72e-2)" "unprognostic (2.03e-1)" "unprognostic (3.09e-1)" "unprognostic (1.11e-1)" "unprognostic (1.64e-1)" "unprognostic (3.44e-1)" "unprognostic (3.96e-1)" "unprognostic (1.80e-1)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (3.01e-1)" "unprognostic (2.40e-1)" "unprognostic (3.27e-2)" "unprognostic (1.60e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (2.00e-2)" FKBP1C bA184C23.2 ENSG00000198225 "FKBP prolyl isomerase family member 1C" 6 63211446-63213024 "Enzymes, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Esophageal apical cells: 2.1;Esophageal suprabasal cells: 1.2;Gastric chief cells: 1.1;Parietal cells: 1.8" "Cell type enhanced" "Detected in some" "Apical squamous epithelial cells: 2.1;Gastric glandular cells: 1.8;Suprabasal cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 3.0;granulocytes: 4.4;monocytes: 5.1" "Not detected" "Not detected" "HPA051330, HPA051798" Uncertain Approved "Golgi apparatus,Primary cilium,Basal body,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 74: Non-specific - Signal transduction" "Cluster 61: BICR 18 - Protein kinases" "Cluster 105: Non-specific - Mixed function" "Golgi apparatus" "Primary cilium, Basal body, Cytosol" "HPA051330: , HPA051798: " "unprognostic (2.15e-3)" "unprognostic (2.24e-1)" FKBP2 "FKBP-13, FKBP13, PPIase" ENSG00000173486 "FKBP prolyl isomerase 2" P26885 11 64241003-64244132 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 35.2;Bergmann glia: 30.4;Brain excitatory neurons: 32.6;Brain inhibitory neurons: 34.2;Choroid plexus epithelial cells: 34.4;Endometrial secretory cells: 46.3;Ependymal cells: 38.2;Hepatocytes: 52.7;Oligodendrocytes: 41.2;Other brain neurons: 50.1;Papillary tip epithelial cells: 30.5;Renal collecting duct principal cells: 32.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 38.2;Glial cells: 41.2;Hepatocytes: 52.7;Neuronal cells: 50.1;Secretory cells: 46.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 931.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 124115658.8;Pancreatic islets: 181225548.4" "Low tissue specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" Enzyme No No 570000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 63: Non-specific - Protein processing" "Cluster 98: Neurons - Neurotransmission & signaling" 15 "Plasma membrane" "CAB025561: , HPA049405: " "unprognostic (3.40e-1)" "unprognostic (8.71e-2)" "unprognostic (1.17e-2)" "unprognostic (1.18e-1)" "unprognostic (5.51e-2)" "unprognostic (1.72e-1)" "unprognostic (5.82e-2)" "unprognostic (1.38e-1)" "unprognostic (7.12e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (1.44e-2)" "unprognostic (1.93e-2)" "unprognostic (1.44e-3)" "unprognostic (4.69e-2)" "unprognostic (3.99e-1)" "unprognostic (3.01e-1)" "unprognostic (5.02e-2)" "unprognostic (9.68e-3)" "unprognostic (1.45e-1)" "unprognostic (2.97e-3)" "unprognostic (1.16e-2)" "unprognostic (1.36e-2)" "unprognostic (2.67e-1)" "unprognostic (1.36e-2)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.83e-2)" "unprognostic (1.89e-1)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (9.18e-2)" FKBP3 "FKBP-25, FKBP25" ENSG00000100442 "FKBP prolyl isomerase 3" Q00688 14 45115599-45135319 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 397.6;tongue: 347.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 410.8;Late spermatids: 621.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 621.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Skeletal myofibers: 275639622.2" "Tissue enhanced" "Detected in all" "skeletal muscle: 238788727.1" "HPA000864, CAB012232, CAB012520" Supported Supported Cytosol NA NA 460000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 15 Cytosol "CAB012232: , CAB012520: , HPA000864: " "unprognostic (2.04e-2)" "unprognostic (1.05e-1)" "unprognostic (1.34e-3)" "unprognostic (2.74e-2)" "unprognostic (1.30e-1)" "unprognostic (1.32e-1)" "unprognostic (2.44e-1)" "unprognostic (1.38e-1)" "unprognostic (4.89e-3)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (2.86e-2)" "unprognostic (9.60e-2)" "unprognostic (1.01e-1)" "unprognostic (1.48e-3)" "unprognostic (2.11e-3)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (2.50e-1)" "unprognostic (6.60e-3)" "unprognostic (2.71e-1)" "unprognostic (2.95e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.53e-3)" "unprognostic (3.24e-2)" "unprognostic (5.03e-1)" "unprognostic (3.56e-2)" "unprognostic (2.54e-2)" "unprognostic (3.06e-1)" "unprognostic (1.64e-1)" "unprognostic (3.82e-1)" "unprognostic (4.08e-2)" FKBP5 "FKBP51, FKBP54, P54, PPIase, Ptg-10" ENSG00000096060 "FKBP prolyl isomerase 5" Q13451 6 35573585-35728583 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Chaperone, Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 833.2;tongue: 864.2" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 1778.0;Monocyte progenitors: 2488.9;Neutrophils: 5747.7;Podocytes: 1716.6;Proximal tubule cells: 1851.2;Thymic myoid cells: 3630.2;Thymocytes: 1884.4" "Cell type enhanced" "Detected in all" "Neutrophils: 5747.7;Stromal cells: 3630.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 453.7;fibroblast: 344.6;leukocyte: 366.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "prostate cancer: 127.9" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "CAB009315, HPA031092, HPA031093, HPA031095" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No 14000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 329 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "CAB009315: , HPA031092: , HPA031093: , HPA031095: " "unprognostic (2.46e-2)" "unprognostic (4.08e-3)" "unprognostic (2.02e-1)" "unprognostic (2.87e-1)" "unprognostic (5.60e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-2)" "unprognostic (1.18e-3)" "unprognostic (1.76e-1)" "unprognostic (1.03e-3)" "unprognostic (5.52e-2)" "unprognostic (1.65e-1)" "unprognostic (1.48e-1)" "unprognostic (2.31e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (8.60e-4)" "unprognostic (5.36e-2)" "unprognostic (4.50e-2)" "unprognostic (9.22e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-2)" "unprognostic (2.27e-1)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (7.00e-3)" "unprognostic (9.21e-2)" "unprognostic (9.21e-3)" "unprognostic (9.13e-3)" "unprognostic (3.72e-2)" "unprognostic (1.28e-1)" "unprognostic (1.97e-1)" FKBP6 "FKBP36, PPIase" ENSG00000077800 "FKBP prolyl isomerase family member 6 (inactive)" O75344 7 73328161-73358637 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Disease variant, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 152 "testis: 53.0" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 33.5;Early primary spermatocytes: 126.1;Early spermatids: 39.3;Late primary spermatocytes: 125.3;Late spermatids: 31.7;Oocytes: 41.4;Undifferentiated spermatogonia: 34.6" "Group enriched" "Detected in some" 8 "Oocytes: 41.4;Spermatogenic cell types: 126.1" "Cell type enhanced" "Detected in some" "fibroblast: 2.1;oligodendrocyte: 1.8" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 1.1" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1711 "Oocytes: 171137.8" "Not detected" "Not detected" "HPA041414, HPA061109" Enhanced Supported "Nucleoli fibrillar center,Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 51 "Nucleoli fibrillar center, Cytosol" "Microtubules, Cytokinetic bridge" "HPA041414: , HPA061109: " "unprognostic (1.73e-1)" FKBP7 FKBP23 ENSG00000079150 "FKBP prolyl isomerase 7" Q9Y680 2 178463664-178478600 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 52.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 168.2;Early spermatids: 259.3;Fibroblasts: 52.8;Hepatic stellate cells: 58.1;Late primary spermatocytes: 76.0;Late spermatids: 65.1;Leydig cells: 53.6;Ovarian stromal cells: 88.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 259.3;Stromal cells: 168.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 10711758.1;Oocytes: 18016949.9" "Tissue enriched" "Detected in all" "ovary: 77722406.2" HPA008707 Approved Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" Enzyme NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 75: Ovary - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 61 "Endoplasmic reticulum" "HPA008707: " "unprognostic (4.13e-1)" "unprognostic (6.01e-2)" "unprognostic (1.85e-1)" "unprognostic (1.03e-1)" "unprognostic (4.63e-2)" "unprognostic (3.90e-2)" "unprognostic (1.53e-1)" "unprognostic (4.99e-2)" "unprognostic (2.14e-2)" "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (3.92e-2)" "unprognostic (9.41e-2)" "unprognostic (4.73e-2)" "unprognostic (2.57e-1)" "unprognostic (3.74e-1)" "unprognostic (1.17e-2)" "unprognostic (1.42e-2)" "unprognostic (1.19e-1)" "unprognostic (5.49e-3)" "unprognostic (4.19e-3)" "unprognostic (4.90e-2)" "unprognostic (3.16e-1)" "unprognostic (2.80e-1)" "unprognostic (1.69e-1)" "unprognostic (1.73e-1)" "unprognostic (3.10e-3)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (1.33e-1)" "unprognostic (8.65e-3)" "unprognostic (1.44e-1)" FKBP8 "FKBP38, FKBPr38" ENSG00000105701 "FKBP prolyl isomerase 8" Q14318 19 18531751-18544077 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Host-virus interaction" "Isomerase, Rotamase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 999.7;Late spermatids: 2216.9;Platelets: 649.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 999.7;Spermatogenic cell types: 2216.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 93.7;neutrophil: 78.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 93.7" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 13245918.1" "Low tissue specificity" "Detected in all" "CAB025346, HPA045177" Supported Supported "Endoplasmic reticulum,Mitochondria,Cytosol" NA NA 6800 "Cluster 19: Eosinophils - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 166 Mitochondria "Endoplasmic reticulum, Cytosol" "CAB025346: , HPA045177: " "unprognostic (2.21e-1)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "unprognostic (7.18e-2)" "unprognostic (6.15e-2)" "unprognostic (1.55e-1)" "unprognostic (3.39e-1)" "unprognostic (4.64e-2)" "unprognostic (7.65e-2)" "unprognostic (1.94e-1)" "unprognostic (3.06e-1)" "unprognostic (1.94e-3)" "unprognostic (1.17e-3)" "unprognostic (7.12e-3)" "unprognostic (1.74e-1)" "unprognostic (3.16e-2)" "unprognostic (1.39e-2)" "unprognostic (1.79e-1)" "unprognostic (8.79e-2)" "unprognostic (2.37e-1)" "unprognostic (2.20e-3)" "unprognostic (1.55e-1)" "unprognostic (8.83e-2)" "unprognostic (6.20e-2)" "unprognostic (5.97e-2)" "unprognostic (1.12e-1)" "unprognostic (3.79e-1)" "unprognostic (4.94e-3)" "unprognostic (4.99e-2)" "unprognostic (1.25e-1)" FKBP9 "FKBP60, FKBP63" ENSG00000122642 "FKBP prolyl isomerase 9" O95302 7 32957404-33006930 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 90.4" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 105.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 31376661.6" "Tissue enriched" "Detected in all" "skin: 99410755.1" "HPA012595, HPA055256" Approved Approved "Golgi apparatus" "Intracellular and membrane" Enzyme No No 140000 "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" "Golgi apparatus" "HPA012595: , HPA055256: " "potential prognostic unfavorable (8.51e-4)" "unprognostic (5.48e-3)" "unprognostic (9.18e-2)" "unprognostic (4.83e-2)" "unprognostic (4.30e-2)" "unprognostic (1.24e-1)" "unprognostic (4.74e-3)" "potential prognostic unfavorable (7.45e-7)" "potential prognostic unfavorable (3.19e-5)" "unprognostic (5.15e-2)" "unprognostic (8.35e-3)" "unprognostic (2.46e-1)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (1.27e-2)" "unprognostic (9.71e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-1)" "unprognostic (1.65e-1)" "unprognostic (3.40e-1)" "unprognostic (2.06e-1)" "unprognostic (4.78e-2)" "unprognostic (1.00e-1)" "unprognostic (1.11e-1)" "unprognostic (3.55e-1)" "unprognostic (1.84e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-2)" "unprognostic (2.28e-1)" "unprognostic (1.91e-3)" "unprognostic (1.42e-1)" FKBPL "DIR1, NG7, WISp39" ENSG00000204315 "FKBP prolyl isomerase like" Q9UIM3 6 32128707-32130288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.3;Ependymal cells: 1.2;Oligodendrocytes: 1.0;Other brain neurons: 1.2;Platelets: 2.8;Renal collecting duct principal cells: 1.2" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.2;Ductal cells: 1.2;Glial cells: 1.3;Neuronal cells: 1.2;Platelets: 2.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 866140.3;Proximal tubules: 612843.7;T-cells: 793653.9" "Group enriched" "Detected in some" "bone marrow: 413559.6;salivary gland: 280589.8" "HPA043478, HPA060158" Approved Approved "Nucleoplasm,Mitotic spindle" Yes No "Cluster 18: Non-specific - Translation" "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 17 Nucleoplasm "Mitotic spindle" "HPA043478: , HPA060158: " "unprognostic (1.48e-1)" "unprognostic (2.76e-2)" "unprognostic (8.00e-2)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (8.58e-3)" "unprognostic (4.00e-1)" "potential prognostic favorable (6.89e-4)" "unprognostic (1.51e-1)" "unprognostic (1.36e-2)" "unprognostic (3.77e-2)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (6.53e-2)" "unprognostic (4.68e-3)" "unprognostic (8.38e-2)" "unprognostic (3.20e-1)" "unprognostic (1.40e-2)" "unprognostic (8.32e-3)" "unprognostic (1.15e-2)" "unprognostic (2.65e-1)" "unprognostic (2.50e-2)" "unprognostic (4.47e-2)" "unprognostic (4.17e-1)" "unprognostic (9.82e-3)" "unprognostic (1.80e-1)" "unprognostic (3.28e-1)" "unprognostic (1.03e-1)" "unprognostic (4.07e-1)" "unprognostic (7.48e-2)" "potential prognostic favorable (9.61e-4)" FLAD1 "FAD1, PP591" ENSG00000160688 "Flavin adenine dinucleotide synthetase 1" Q8NFF5 1 154983338-154993111 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 126.0" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 126.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA028476, HPA028486, HPA028563" Approved Approved "Plasma membrane,Cytokinetic bridge,Primary cilium,Cytosol,Mid piece,Principal piece,End piece" Yes NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 9 "Plasma membrane, Cytosol" "Cytokinetic bridge, Primary cilium, Mid piece, Principal piece, End piece" "HPA028476: , HPA028486: , HPA028563: " "unprognostic (2.45e-1)" "unprognostic (1.90e-2)" "unprognostic (4.03e-1)" "unprognostic (8.17e-2)" "unprognostic (3.07e-2)" "unprognostic (2.01e-2)" "unprognostic (3.45e-1)" "unprognostic (1.84e-3)" "unprognostic (2.46e-1)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (2.46e-7)" "unprognostic (4.23e-3)" "unprognostic (4.57e-2)" "unprognostic (1.91e-3)" "unprognostic (3.65e-2)" "unprognostic (8.00e-3)" "unprognostic (2.08e-2)" "unprognostic (3.59e-2)" "unprognostic (6.66e-2)" "unprognostic (3.28e-1)" "unprognostic (2.80e-1)" "unprognostic (3.94e-2)" "unprognostic (5.97e-2)" "unprognostic (2.44e-2)" "unprognostic (3.73e-1)" "unprognostic (3.31e-1)" "unprognostic (1.71e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (2.02e-2)" "unprognostic (8.04e-2)" FLI1 "EWSR2, FLI-1, SIC-1" ENSG00000151702 "Fli-1 proto-oncogene, ETS transcription factor" Q01543 11 128686535-128813267 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 65.9" "Cell type enhanced" "Detected in many" "B-cells: 294.4;Hematopoietic stem cells: 388.7;Kupffer cells: 233.7;Lymphatic endothelial cells: 318.8;Macrophages: 258.1;Megakaryocyte progenitors: 736.7;Microglia: 514.2;Monocyte progenitors: 404.2;monocytes: 251.5;Neutrophil progenitors: 778.5;Neutrophils: 839.9;NK-cells: 256.8;Platelets: 244.1;T-cells: 223.2;Thymocytes: 269.3;Vascular endothelial cells: 529.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 529.2;Glial cells: 514.2;Megakaryocytes: 736.7;Neutrophils: 839.9" "Group enriched" "Detected in many" 11 "central nervous system macrophage: 678.7;endothelial cell: 1439.5;leukocyte: 457.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 39.0;Myeloma: 29.4" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 6301679.7;Neutrophils: 8178466.0;T-cells: 6002159.8" "Group enriched" "Detected in some" "bone marrow: 1266295.1;cerebral cortex: 2884992.5;lymphoid tissue: 2623516.4" "HPA065030, HPA073099" Approved Supported "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 104: Brain endothelial cells - Blood brain barrier" 11 "Nuclear bodies" Nucleoplasm "HPA065030: , HPA073099: " "unprognostic (1.26e-1)" "unprognostic (6.03e-2)" "unprognostic (7.07e-3)" "unprognostic (9.59e-2)" "unprognostic (6.28e-2)" "unprognostic (4.57e-2)" "unprognostic (1.74e-1)" "unprognostic (1.37e-1)" "unprognostic (4.97e-3)" "unprognostic (1.72e-2)" "validated prognostic favorable (6.17e-9)" "validated prognostic favorable (6.48e-4)" "unprognostic (1.48e-3)" "unprognostic (1.10e-2)" "unprognostic (3.08e-2)" "unprognostic (1.15e-1)" "unprognostic (9.11e-2)" "unprognostic (3.26e-1)" "unprognostic (3.47e-3)" "unprognostic (2.19e-2)" "unprognostic (4.15e-2)" "unprognostic (3.00e-3)" "unprognostic (1.81e-1)" "unprognostic (1.34e-1)" "unprognostic (1.61e-1)" "unprognostic (7.61e-2)" "unprognostic (2.90e-2)" "unprognostic (2.23e-2)" "unprognostic (8.62e-2)" "unprognostic (1.13e-2)" FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 587.8;skeletal muscle: 1324.7;tongue: 413.4" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 127.5;Myonuclei: 137.4;Smooth muscle cells: 273.4;Thymic myoid cells: 165.9" "Group enriched" "Detected in many" 4 "Myocytes: 137.4;Smooth muscle cells: 273.4;Stromal cells: 165.9" "Cell type enhanced" "Detected in many" "astrocyte: 11.5;ependymal cell: 27.8;vascular associated smooth muscle cell: 12.2" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 45.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Spleen - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Skeletal myofibers: 15337208665.5" "Tissue enhanced" "Detected in all" "skeletal muscle: 5574839841.8" "HPA006135, HPA071007" Enhanced Approved "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 42 "Plasma membrane, Cytosol" "HPA006135: , HPA071007: " "unprognostic (6.40e-3)" "unprognostic (9.74e-2)" "unprognostic (8.43e-2)" "unprognostic (7.18e-2)" "unprognostic (7.42e-2)" "unprognostic (3.21e-2)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (2.39e-3)" "unprognostic (5.73e-3)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (5.48e-3)" "unprognostic (2.07e-1)" "unprognostic (3.06e-3)" "unprognostic (7.02e-3)" "potential prognostic unfavorable (1.44e-8)" "unprognostic (9.73e-3)" "unprognostic (1.89e-3)" "unprognostic (1.63e-1)" "unprognostic (7.06e-3)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (2.41e-1)" "unprognostic (3.64e-2)" "unprognostic (7.25e-3)" "unprognostic (3.94e-3)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (7.70e-3)" "unprognostic (1.05e-1)" "unprognostic (1.06e-1)" FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 21.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 359.6;Alveolar cells type 2: 214.0;Basal prostatic cells: 168.0;Epididymal basal cells: 85.4;Podocytes: 214.7;Transitional alveolar cells: 203.6" "Cell type enhanced" "Detected in many" "Alveolar cells: 359.6;Basal cells: 168.0;Renal nephron cells: 214.7" "Cell type enhanced" "Detected in all" "hippocampal dentate gyrus: 132.0" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 48.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 12051902.9" "Group enriched" "Detected in some" "cerebral cortex: 2701681.9;intestine: 5136804.8;kidney: 6598762.7;lung: 5405886.3" HPA056033 Enhanced Supported "Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" "Developmental protein" NA NA 210000 "Cluster 72: Kidney - Transmembrane transport" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 81: Alveolar cells - Lung function" 3 "Plasma membrane" "Vesicles, Cell Junctions" "HPA056033: " "unprognostic (3.38e-3)" "unprognostic (2.91e-1)" "unprognostic (1.88e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-2)" "unprognostic (6.24e-2)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (3.83e-2)" "validated prognostic favorable (2.15e-10)" "validated prognostic favorable (4.93e-4)" "unprognostic (1.29e-3)" "unprognostic (2.84e-2)" "unprognostic (4.20e-2)" "unprognostic (2.31e-2)" "unprognostic (5.01e-3)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (5.01e-2)" "unprognostic (5.80e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.30e-3)" "unprognostic (1.88e-1)" "unprognostic (4.54e-2)" "unprognostic (1.92e-1)" "unprognostic (2.48e-1)" "unprognostic (3.25e-2)" "unprognostic (9.41e-2)" "unprognostic (6.36e-3)" "unprognostic (8.84e-3)" FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 394.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 308.8;Extravillous trophoblasts: 1644.7;Late spermatids: 279.5;Migrating cytotrophoblasts: 449.7;Müller glia: 545.6;Neutrophils: 284.2;Syncytiotrophoblasts: 1703.8;Vascular endothelial cells: 1218.5" "Group enriched" "Detected in many" 4 "Endothelial cells: 1218.5;Glial cells: 545.6;Trophoblast cells: 1703.8" "Cell type enriched" "Detected in many" 12 "endothelial cell: 3142.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 123.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 15.1;testis cancer: 39.8" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Glomeruli: 17418439.6" "Tissue enriched" "Detected in single" 1602 "skeletal muscle: 160212.6" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Secreted to blood" Receptor NA NA 876000 300000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 21 "Plasma membrane" "Actin filaments, Cytosol" "CAB068189: , CAB068190: , HPA011740: , HPA014290: " "unprognostic (1.82e-1)" "unprognostic (2.40e-2)" "unprognostic (2.03e-1)" "unprognostic (3.42e-3)" "unprognostic (4.86e-3)" "unprognostic (3.34e-2)" "unprognostic (2.12e-1)" "unprognostic (5.01e-3)" "unprognostic (6.22e-2)" "unprognostic (1.45e-1)" "validated prognostic favorable (2.61e-8)" "validated prognostic favorable (3.90e-4)" "unprognostic (1.78e-3)" "unprognostic (7.66e-2)" "unprognostic (1.43e-1)" "unprognostic (4.42e-3)" "unprognostic (9.15e-3)" "unprognostic (2.65e-3)" "unprognostic (2.15e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (3.90e-1)" "unprognostic (2.96e-3)" "unprognostic (2.92e-1)" "unprognostic (1.41e-2)" "unprognostic (9.98e-2)" "unprognostic (4.56e-2)" "unprognostic (1.28e-2)" "unprognostic (6.21e-2)" "unprognostic (7.24e-2)" "unprognostic (6.25e-3)" FMO5 ENSG00000131781 "Flavin containing dimethylaniline monoxygenase 5" P49326 1 147175351-147243050 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Monooxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 638.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 234.4;Cardiomyocytes: 237.9;Cholangiocytes: 220.6;Enterocytes: 163.2;Gastric chief cells: 214.0;Hepatocytes: 434.2;Lacrimal acinar cells: 152.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 434.2;Myocytes: 237.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 158.3;Lung Adenocarcinoma (TCGA): 41.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "liver cancer: 9.0" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Hepatocytes: 180105681.3" "Tissue enriched" "Detected in many" "liver: 194876995.9" HPA012373 Enhanced Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Endoplasmic reticulum, Cytosol" "HPA012373: " "unprognostic (3.90e-2)" "unprognostic (2.61e-1)" "unprognostic (1.41e-2)" "unprognostic (8.89e-2)" "unprognostic (4.56e-2)" "unprognostic (1.69e-1)" "unprognostic (4.00e-2)" "unprognostic (3.19e-2)" "unprognostic (2.89e-2)" "potential prognostic favorable (3.67e-4)" "unprognostic (2.00e-2)" "potential prognostic favorable (6.75e-4)" "unprognostic (9.38e-2)" "unprognostic (1.14e-1)" "unprognostic (1.07e-2)" "unprognostic (3.71e-1)" "unprognostic (1.20e-2)" "unprognostic (3.41e-2)" "unprognostic (1.62e-1)" "unprognostic (6.44e-2)" "unprognostic (3.21e-1)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (4.06e-1)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (4.11e-2)" "unprognostic (7.98e-2)" "unprognostic (2.32e-1)" "unprognostic (1.10e-1)" "unprognostic (1.14e-2)" FMR1 "FMRP, FRAXA, MGC87458, POF, POF1" ENSG00000102081 "Fragile X messenger ribonucleoprotein 1" Q06787 X 147911919-147951125 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Neurogenesis, RNA-mediated gene silencing, Translation regulation, Transport" "Activator, Repressor, Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability, Neurodegeneration, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 12880757.3" "Tissue enhanced" "Detected in many" "heart muscle: 4873136.0" "CAB012444, HPA050118, HPA056084" Approved Enhanced Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 81 Cytosol "CAB012444: , HPA050118: , HPA056084: " "unprognostic (1.63e-1)" "unprognostic (1.79e-2)" "unprognostic (7.53e-2)" "unprognostic (1.02e-1)" "unprognostic (1.11e-1)" "unprognostic (1.72e-1)" "unprognostic (9.71e-2)" "unprognostic (3.39e-2)" "unprognostic (2.29e-1)" "unprognostic (5.37e-2)" "potential prognostic favorable (1.09e-5)" "unprognostic (1.14e-1)" "unprognostic (1.26e-1)" "unprognostic (4.07e-1)" "unprognostic (3.74e-1)" "unprognostic (2.59e-1)" "unprognostic (1.33e-1)" "unprognostic (3.40e-2)" "unprognostic (5.00e-2)" "unprognostic (4.75e-2)" "unprognostic (3.17e-1)" "unprognostic (1.16e-2)" "unprognostic (1.54e-2)" "unprognostic (1.33e-2)" "unprognostic (9.36e-3)" "unprognostic (6.97e-3)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "unprognostic (2.29e-1)" "unprognostic (4.10e-2)" "unprognostic (1.91e-1)" FN3K ENSG00000167363 "Fructosamine 3 kinase" Q9H479 17 82735615-82751196 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 73.1;Retinal ganglion cells: 88.8;Somatotrophs: 102.9" "Cell type enhanced" "Detected in many" "Pituitary endocrine cells: 102.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "cerebral cortex: 36739143.3" "HPA059151, HPA061358" Supported Enhanced Mitochondria NA NA 300000 "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" 2 Mitochondria "HPA059151: , HPA061358: " "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (7.55e-2)" "unprognostic (9.19e-2)" "unprognostic (2.16e-2)" "unprognostic (1.50e-2)" "unprognostic (4.29e-2)" "unprognostic (4.67e-3)" "unprognostic (8.74e-2)" "unprognostic (1.27e-2)" "potential prognostic favorable (7.20e-7)" "unprognostic (1.86e-1)" "unprognostic (1.76e-1)" "unprognostic (7.20e-2)" "unprognostic (7.41e-2)" "unprognostic (1.63e-1)" "unprognostic (9.65e-2)" "unprognostic (1.31e-1)" "unprognostic (4.58e-2)" "unprognostic (6.76e-2)" "unprognostic (1.52e-2)" "unprognostic (2.28e-3)" "unprognostic (6.34e-2)" "unprognostic (9.93e-3)" "unprognostic (2.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-2)" "unprognostic (2.41e-2)" "unprognostic (3.01e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" FOS "AP-1, c-fos" ENSG00000170345 "Fos proto-oncogene, AP-1 transcription factor subunit" P01100 14 75278826-75282230 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 6299.3;Endometrial luminal cells: 6202.5;Neutrophils: 6881.5;Ovarian stromal cells: 5794.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "astrocyte: 259.9;central nervous system macrophage: 281.5;endothelial cell: 364.6;ependymal cell: 315.8;vascular associated smooth muscle cell: 860.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 506.6" "Lineage enriched" "Detected in many" 6 "granulocytes: 506.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "cerebellum: 114.4;spinal cord: 324.5" "Cell type enriched" "Detected in single" 7858 "Keratinocytes: 785797.2" "Not detected" "Not detected" "HPA018531, CAB080210" Approved Supported Nucleoplasm Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 122 Nucleoplasm "CAB080210: , HPA018531: " "unprognostic (2.84e-1)" "unprognostic (6.00e-2)" "unprognostic (1.05e-3)" "unprognostic (1.03e-2)" "unprognostic (3.97e-2)" "unprognostic (4.06e-2)" "unprognostic (1.71e-2)" "unprognostic (1.61e-1)" "unprognostic (4.99e-2)" "unprognostic (1.67e-1)" "unprognostic (3.67e-3)" "unprognostic (2.03e-3)" "unprognostic (1.67e-2)" "unprognostic (1.56e-1)" "unprognostic (2.96e-3)" "unprognostic (2.73e-2)" "unprognostic (1.37e-2)" "unprognostic (6.04e-2)" "unprognostic (1.69e-1)" "unprognostic (1.54e-3)" "unprognostic (2.17e-1)" "unprognostic (9.12e-2)" "unprognostic (1.12e-1)" "unprognostic (2.90e-3)" "unprognostic (2.01e-1)" "unprognostic (2.38e-3)" "unprognostic (1.17e-2)" "unprognostic (8.11e-3)" "unprognostic (3.80e-1)" "unprognostic (1.85e-1)" "unprognostic (1.24e-1)" FOSB "AP-1, DKFZp686C0818, G0S3, GOS3, GOSB, MGC42291" ENSG00000125740 "FosB proto-oncogene, AP-1 transcription factor subunit" P53539 19 45467995-45475179 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 1691.8;Breast secretory cells: 2187.2;Endometrial luminal cells: 1976.3;Mast cells: 1960.3;Salivary myoepithelial cells: 1716.6" "Low cell type specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "vascular associated smooth muscle cell: 65.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 90.4" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Neurons: 65269.6" "Tissue enriched" "Detected in single" 13185 "ovary: 1318497.2" "CAB010267, HPA054663" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 20: Non-specific - Transcription regulation" 39 Nucleoplasm Vesicles "CAB010267: , HPA054663: " "unprognostic (3.06e-2)" "unprognostic (1.90e-1)" "potential prognostic favorable (6.37e-4)" "unprognostic (3.02e-1)" "unprognostic (5.08e-2)" "unprognostic (1.77e-1)" "unprognostic (1.19e-2)" "unprognostic (1.59e-1)" "unprognostic (3.21e-1)" "unprognostic (7.16e-2)" "validated prognostic favorable (3.68e-4)" "validated prognostic favorable (1.07e-7)" "unprognostic (2.35e-2)" "unprognostic (1.06e-2)" "unprognostic (1.90e-3)" "unprognostic (2.52e-3)" "unprognostic (1.20e-1)" "unprognostic (2.32e-2)" "unprognostic (1.63e-1)" "unprognostic (1.55e-2)" "unprognostic (1.24e-2)" "unprognostic (3.28e-1)" "unprognostic (4.40e-2)" "unprognostic (1.13e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-2)" "unprognostic (5.16e-2)" "unprognostic (1.83e-3)" "unprognostic (1.14e-1)" "unprognostic (4.83e-2)" "unprognostic (1.55e-2)" FOSL2 "FLJ23306, FRA2" ENSG00000075426 "FOS like 2, AP-1 transcription factor subunit" P15408 2 28392448-28417317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 430.0;Esophageal apical cells: 455.4;monocytes: 475.3;Neutrophils: 697.0" "Cell type enhanced" "Detected in all" "Neutrophils: 697.0" "Group enriched" "Detected in many" 4 "endothelial cell: 126.2;leukocyte: 115.9;vascular associated smooth muscle cell: 224.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 36.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Keratinocytes: 305158.7;Neurons: 249803.9" "Tissue enriched" "Detected in some" "ovary: 537072.1" "HPA004817, CAB013460, HPA061417" Supported Enhanced Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 103: Non-specific - Basic cellular processes" 49 Nucleoplasm "CAB013460: , HPA004817: , HPA061417: " "unprognostic (9.31e-3)" "unprognostic (4.86e-2)" "unprognostic (2.91e-1)" "unprognostic (1.23e-2)" "unprognostic (4.93e-2)" "unprognostic (4.47e-2)" "unprognostic (4.60e-3)" "unprognostic (1.79e-1)" "unprognostic (5.00e-2)" "unprognostic (3.80e-1)" "unprognostic (4.94e-2)" "unprognostic (3.65e-2)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-3)" "unprognostic (1.03e-2)" "unprognostic (1.75e-1)" "unprognostic (7.04e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (1.00e-1)" "unprognostic (8.48e-3)" "unprognostic (1.54e-1)" "unprognostic (1.06e-1)" "unprognostic (8.91e-2)" "unprognostic (4.51e-3)" "unprognostic (2.98e-2)" "unprognostic (2.16e-1)" "unprognostic (2.23e-2)" "unprognostic (1.64e-2)" "unprognostic (1.28e-1)" FOXC2 "FKHL14, MFH-1" ENSG00000176692 "Forkhead box C2" Q99958 16 86566829-86569728 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "blood vessel: 37.0" "Cell type enhanced" "Detected in some" "Hepatic stellate cells: 12.9;Lymphatic endothelial cells: 81.0;Ocular epithelial cells: 23.0;Pericytes: 24.0;Peritubular myoid cells: 36.1;Podocytes: 23.2;Salivary basal cells: 16.2;Submucosal glandular cells: 13.9;Undifferentiated spermatogonia: 13.9;Vascular smooth muscle cells: 69.4" "Cell type enhanced" "Detected in some" "Endothelial cells: 81.0;Mural cells: 69.4;Stromal cells: 36.1" "Group enriched" "Detected in some" 36 "fibroblast: 76.7;pericyte: 61.8;vascular associated smooth muscle cell: 82.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 7.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 16.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Lung - Smooth muscle cells" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 6 "spinal cord: 56.3" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 53228 "skin: 5322795.4" HPA056302 Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 7 "Nucleoplasm, Nuclear bodies" "HPA056302: " "unprognostic (2.49e-1)" "unprognostic (3.03e-2)" "unprognostic (1.45e-1)" "unprognostic (7.64e-3)" "unprognostic (2.11e-2)" "unprognostic (4.52e-2)" "unprognostic (2.25e-2)" "unprognostic (1.46e-2)" "unprognostic (2.04e-2)" "unprognostic (3.06e-2)" "unprognostic (7.70e-2)" "unprognostic (3.00e-1)" "unprognostic (6.25e-2)" "unprognostic (3.39e-3)" "unprognostic (3.42e-2)" FOXD4L1 FOXD5 ENSG00000184492 "Forkhead box D4 like 1" Q9NU39 2 113498665-113501150 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.0;testis: 1.1" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.0;Sertoli cells: 1.1" "Cell type enhanced" "Detected in some" "Ductal cells: 2.0;Reproductive supporting cells: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 2.0" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012836, HPA069839" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 19 Nucleoplasm Cytosol "HPA012836: , HPA069839: " "unprognostic (1.82e-1)" FOXP3 "AIID, DIETER, IPEX, JM2, PIDX, SCURFIN, XPID" ENSG00000049768 "Forkhead box P3" Q9BZS1 X 49250438-49264800 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 4.9;lymphoid tissue: 6.6" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 1.6;Epididymal principal cells: 4.0;T-cells: 9.2;Thymic myoid cells: 1.4;Undifferentiated spermatogonia: 1.7" "Cell type enhanced" "Detected in some" "Reproductive supporting cells: 4.0;T-cells: 9.2" "Cell type enhanced" "Detected in single" "leukocyte: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 11 "T-reg: 52.0" "Lineage enriched" "Detected in single" 360 "T-cells: 52.0" "Cancer enhanced" "Detected in some" "lymphoma: 3.7" "Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 2608 "B-cells: 379203.4;T-cells: 142467.4" "Tissue enriched" "Detected in single" 227 "Stomach: 22717.6" "CAB026301, HPA045943, HPA069372" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 34 Nucleoplasm Cytosol "CAB026301: , HPA045943: , HPA069372: " "potential prognostic favorable (3.53e-4)" "unprognostic (8.91e-2)" "unprognostic (7.65e-2)" "potential prognostic favorable (3.29e-4)" "unprognostic (2.03e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (2.20e-4)" "unprognostic (5.16e-2)" "potential prognostic unfavorable (1.98e-6)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (9.07e-4)" "unprognostic (8.74e-2)" "unprognostic (5.00e-2)" "unprognostic (1.43e-1)" "unprognostic (3.17e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.41e-2)" "unprognostic (3.31e-3)" "unprognostic (4.36e-3)" "unprognostic (1.59e-1)" "unprognostic (6.66e-2)" "unprognostic (3.40e-3)" "unprognostic (2.96e-2)" "unprognostic (1.99e-2)" "unprognostic (6.26e-2)" "unprognostic (3.03e-1)" "unprognostic (1.68e-1)" FOXQ1 HFH1 ENSG00000164379 "Forkhead box Q1" Q9C009 6 1312098-1314758 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 101.2;urinary bladder: 50.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 82.1;Foveolar cells: 456.5;Gastric progenitor cells: 133.3;Mucous neck cells: 203.6;Ocular epithelial cells: 151.9;Prostatic club cells: 193.1;Prostatic hillock cells: 165.0;Salivary basal cells: 129.0;Salivary duct cells: 144.5;Urothelial cells: 273.8" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 273.8;Ductal cells: 144.5;Gastric glandular cells: 456.5;Glandular cells: 193.1" "Cell type enhanced" "Detected in some" "endothelial cell: 122.7;fibroblast: 37.2;pericyte: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 53.8" "Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059700, CAB080325, CAB080326" Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" Yes NA "Cluster 60: Stomach - Digestion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 68: Foveolar cells - Mucosal defense" 1 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "CAB080325: , CAB080326: , HPA059700: " "potential prognostic favorable (1.11e-4)" "potential prognostic favorable (3.84e-4)" "unprognostic (2.13e-2)" "unprognostic (2.42e-1)" "unprognostic (7.28e-2)" "unprognostic (7.10e-3)" "unprognostic (3.95e-3)" "unprognostic (2.76e-1)" "unprognostic (3.25e-1)" "unprognostic (3.11e-1)" "unprognostic (4.50e-2)" "unprognostic (4.08e-3)" "unprognostic (1.07e-3)" "unprognostic (1.14e-2)" "unprognostic (1.67e-2)" "unprognostic (2.16e-2)" "unprognostic (4.31e-2)" "unprognostic (7.18e-2)" "unprognostic (2.70e-1)" "unprognostic (6.57e-2)" "unprognostic (3.28e-1)" "unprognostic (3.85e-3)" "unprognostic (2.68e-2)" "unprognostic (1.12e-2)" "unprognostic (1.54e-1)" "unprognostic (1.02e-2)" "unprognostic (4.53e-2)" "unprognostic (3.11e-2)" "unprognostic (1.99e-1)" "unprognostic (1.76e-1)" "unprognostic (4.87e-2)" FRAT2 ENSG00000181274 "FRAT regulator of WNT signaling pathway 2" O75474 10 97332497-97334729 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 64.0;Late spermatids: 65.1;Neutrophil progenitors: 77.4;Neutrophils: 285.7" "Cell type enriched" "Detected in many" 4 "Neutrophils: 285.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Testicular Germ Cell Tumor (TCGA): 107.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "eosinophil: 15.0;neutrophil: 58.4" "Lineage enriched" "Detected in all" 7 "granulocytes: 58.4" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA049763 Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 Nucleoplasm Mitochondria "HPA049763: " "unprognostic (2.98e-2)" "unprognostic (1.01e-2)" "unprognostic (8.44e-2)" "unprognostic (3.90e-2)" "unprognostic (2.22e-1)" "unprognostic (1.36e-1)" "unprognostic (5.08e-2)" "unprognostic (2.61e-3)" "unprognostic (5.25e-2)" "unprognostic (1.89e-1)" "potential prognostic favorable (2.53e-4)" "unprognostic (7.98e-2)" "unprognostic (1.77e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-2)" "unprognostic (2.18e-2)" "unprognostic (1.89e-1)" "unprognostic (9.35e-3)" "unprognostic (1.14e-2)" "unprognostic (1.71e-1)" "unprognostic (2.08e-1)" "unprognostic (9.45e-2)" "potential prognostic favorable (3.31e-4)" "unprognostic (5.24e-2)" "unprognostic (5.58e-3)" "unprognostic (1.40e-1)" "unprognostic (2.08e-1)" "unprognostic (3.09e-2)" "unprognostic (1.69e-1)" "unprognostic (7.12e-2)" "unprognostic (6.64e-3)" FRYL "AF4p12, DKFZp686E205, KIAA0826, MOR2" ENSG00000075539 "FRY like transcription coactivator" O94915 4 48497357-48780322 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Goblet cells: 849.0;Oligodendrocytes: 1417.3" "Cell type enhanced" "Detected in many" "Glial cells: 1417.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 2067.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "basophil: 13.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 13.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "intestine: 7193383.0" "HPA031106, HPA031107" Supported Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 46: Basophils - Proteolysis" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 11: White matter - Signal transduction" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 26 Cytosol "Microtubules, Cytokinetic bridge" "HPA031106: , HPA031107: " "unprognostic (1.30e-1)" "unprognostic (1.84e-1)" "unprognostic (3.67e-2)" "unprognostic (5.92e-3)" "unprognostic (6.43e-2)" "unprognostic (2.04e-2)" "unprognostic (4.88e-2)" "unprognostic (2.99e-2)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (2.01e-4)" "validated prognostic favorable (1.37e-7)" "validated prognostic favorable (7.04e-5)" "unprognostic (9.50e-2)" "unprognostic (1.21e-1)" "unprognostic (2.55e-2)" "unprognostic (1.00e-2)" "unprognostic (2.22e-3)" "unprognostic (3.46e-1)" "unprognostic (2.77e-1)" "unprognostic (1.01e-2)" "unprognostic (3.41e-3)" "unprognostic (4.80e-3)" "unprognostic (1.06e-1)" "unprognostic (3.27e-1)" "potential prognostic favorable (7.14e-4)" "unprognostic (3.11e-1)" "unprognostic (1.50e-1)" "unprognostic (9.80e-2)" "unprognostic (1.99e-1)" "unprognostic (2.57e-2)" "unprognostic (1.61e-1)" FSIP1 FLJ35989 ENSG00000150667 "Fibrous sheath interacting protein 1" Q8NA03 15 39588357-39782841 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 10.3;testis: 6.8" "Cell type enhanced" "Detected in many" "Ependymal cells: 234.9;Epicardial cells: 666.3;Platelets: 139.2;Salivary myoepithelial cells: 175.4" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 666.3" "Cell type enhanced" "Detected in all" "ependymal cell: 264.3" "Group enriched" "Detected in some" 8 "Breast Invasive Carcinoma (TCGA): 16.2;Colon Adenocarcinoma (TCGA): 9.6;Rectum Adenocarcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.0" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041002 Uncertain Approved "Nucleoplasm,Flagellar centriole,Annulus" NA NA "Cluster 21: Testis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Nucleoplasm, Flagellar centriole, Annulus" "HPA041002: " "unprognostic (9.15e-2)" "unprognostic (1.11e-1)" "unprognostic (4.09e-2)" "potential prognostic favorable (1.92e-4)" "unprognostic (1.17e-2)" "unprognostic (3.05e-2)" "unprognostic (1.36e-3)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.41e-1)" FST FS ENSG00000134363 Follistatin P19883 5 53480626-53487134 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 66.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 101.6;Decidual stromal cells: 50.5;Fibroblasts: 70.1;Granulosa cells: 76.2;Hepatocytes: 86.1;Pancreatic acinar cells: 46.9;Salivary basal cells: 47.0;Salivary myoepithelial cells: 54.3;Thymic myoid cells: 54.4;Undifferentiated spermatogonia: 32.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 70.1;Hepatocytes: 86.1;Reproductive supporting cells: 76.2;Secretory gland support: 101.6" "Cell type enhanced" "Detected in many" "miscellaneous: 7.6" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 97.1;Liver Hepatocellular Carcinoma (TCGA): 98.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 415.0;head and neck cancer: 203.7" "Kidney - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 9591 "Granulosa cells: 1525679.3;Oocytes: 392519.5" "Tissue enriched" "Detected in single" 204 "ovary: 20436.4" "HPA016612, CAB026025" Approved Approved Vesicles "Secreted to blood" "No annotated function" NA NA 1290000 8000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 10 Vesicles "CAB026025: , HPA016612: " "unprognostic (1.02e-1)" "unprognostic (2.12e-1)" "unprognostic (2.02e-2)" "unprognostic (8.27e-3)" "unprognostic (3.96e-2)" "unprognostic (1.66e-1)" "unprognostic (1.65e-1)" "unprognostic (9.85e-2)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (2.63e-2)" "unprognostic (1.63e-1)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (8.56e-5)" "unprognostic (6.03e-2)" "unprognostic (6.75e-2)" "unprognostic (7.80e-3)" "unprognostic (3.13e-1)" "unprognostic (1.81e-2)" "unprognostic (5.42e-3)" "unprognostic (2.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.77e-2)" "unprognostic (2.07e-2)" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.66e-1)" "unprognostic (2.89e-1)" "unprognostic (1.87e-3)" "unprognostic (2.32e-1)" "unprognostic (3.73e-2)" "unprognostic (5.76e-2)" FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136160-46155579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 914.3" "Cell type enhanced" "Detected in some" "Cholangiocytes: 140.8;Early spermatids: 92.7;Hepatocytes: 556.1;Late primary spermatocytes: 127.7;Late spermatids: 184.2;Oocytes: 405.2;Proximal tubule cells: 507.4" "Group enriched" "Detected in many" 16 "Ductal cells: 140.8;Hepatocytes: 556.1;Oocytes: 405.2;Renal nephron cells: 507.4;Spermatogenic cell types: 184.2" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 232.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 7.5" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Hepatocytes: 1139739897.6;Proximal tubules: 364717425.8" "Tissue enriched" "Detected in many" "liver: 1163527406.6" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" No NA 760000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 34: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 6 Cytosol "Plasma membrane" "HPA020073: , HPA030928: , HPA030929: , HPA036114: " "unprognostic (5.12e-2)" "validated prognostic favorable (2.22e-6)" "validated prognostic favorable (4.89e-4)" "potential prognostic favorable (3.32e-5)" "validated prognostic favorable (4.76e-4)" "validated prognostic favorable (2.08e-4)" "unprognostic (6.88e-2)" "unprognostic (3.71e-2)" "unprognostic (1.67e-3)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (1.78e-1)" FTH1 "FHC, FTH, FTHL6, PIG15, PLIF" ENSG00000167996 "Ferritin heavy chain 1" P02794 11 61959718-61967634 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Iron storage" Oxidoreductase "Cancer-related genes, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 27164.6;cDC: 17857.5;Colonocytes: 17788.5;Enterocytes: 24665.7;Esophageal apical cells: 70832.9;Kupffer cells: 17676.6;Neutrophils: 24197.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 70832.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1714.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 425432448.9;Microglia and Neuropil: 210595046.5" "Tissue enhanced" "Detected in all" "cerebral cortex: 1820688809.6" "CAB008623, CAB080735, CAB080736, CAB080737" Approved Supported Vesicles,Cytosol NA NA 2800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" 44 Vesicles Cytosol "CAB008623: , CAB080735: , CAB080736: , CAB080737: " "unprognostic (1.98e-2)" "unprognostic (6.36e-2)" "unprognostic (1.46e-1)" "unprognostic (1.19e-1)" "unprognostic (1.30e-1)" "unprognostic (9.58e-2)" "unprognostic (3.19e-2)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (4.20e-3)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (6.80e-3)" "unprognostic (2.87e-2)" "validated prognostic unfavorable (3.05e-4)" "validated prognostic unfavorable (1.12e-4)" "unprognostic (1.91e-2)" "unprognostic (3.41e-2)" "unprognostic (9.69e-2)" "unprognostic (1.76e-2)" "unprognostic (2.11e-1)" "unprognostic (1.99e-1)" "unprognostic (1.47e-2)" "unprognostic (9.86e-3)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (6.98e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-1)" "unprognostic (1.74e-1)" "unprognostic (3.31e-1)" "unprognostic (6.70e-2)" FTO "ALKBH9, KIAA1752, MGC5149" ENSG00000140718 "FTO alpha-ketoglutarate dependent dioxygenase" Q9C0B1 16 53701692-54158512 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase, Transferase" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Respiratory ciliated cells: 2047.8" "Cell type enhanced" "Detected in all" "Ciliated cells: 2047.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB017123, HPA041086, HPA068695" Enhanced Supported Vesicles,Cytosol No No 1200000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 9 Cytosol Vesicles "CAB017123: , HPA041086: , HPA068695: " "unprognostic (2.04e-1)" "unprognostic (3.19e-2)" "unprognostic (2.98e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (2.97e-2)" "unprognostic (3.87e-1)" "unprognostic (9.48e-2)" "unprognostic (6.33e-2)" "unprognostic (3.69e-2)" "potential prognostic favorable (9.43e-6)" "unprognostic (1.78e-1)" "unprognostic (4.68e-2)" "unprognostic (2.19e-3)" "unprognostic (2.00e-1)" "unprognostic (1.07e-2)" "unprognostic (1.20e-1)" "unprognostic (2.67e-2)" "unprognostic (1.05e-1)" "unprognostic (1.00e-2)" "unprognostic (1.38e-3)" "unprognostic (1.97e-2)" "unprognostic (3.31e-1)" "unprognostic (1.15e-1)" "unprognostic (2.08e-1)" "unprognostic (9.74e-2)" "unprognostic (1.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.48e-1)" "unprognostic (4.47e-3)" "unprognostic (5.06e-2)" FTSJ3 SPB1 ENSG00000108592 "FtsJ RNA 2'-O-methyltransferase 3" Q8IY81 17 63819433-63830012 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA055544, HPA062628" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 133 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA055544: , HPA062628: " "unprognostic (1.01e-1)" "unprognostic (2.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.37e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (6.49e-2)" "unprognostic (1.92e-3)" "unprognostic (1.04e-1)" "unprognostic (7.42e-3)" "unprognostic (1.65e-3)" "unprognostic (5.49e-2)" "unprognostic (7.74e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (1.27e-3)" "unprognostic (4.01e-3)" "potential prognostic unfavorable (1.66e-5)" "unprognostic (1.34e-1)" "unprognostic (4.80e-3)" "unprognostic (1.11e-1)" "unprognostic (1.73e-1)" "unprognostic (1.45e-1)" "unprognostic (3.13e-1)" "unprognostic (5.80e-2)" "unprognostic (4.15e-3)" "unprognostic (6.31e-2)" "unprognostic (2.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.34e-1)" "unprognostic (7.24e-2)" "unprognostic (1.70e-1)" FUT4 "CD15, ELFT, FCT3A, FUC-TIV" ENSG00000196371 "Fucosyltransferase 4" P22083 11 94543921-94549895 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Inflammatory response" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "bone marrow: 96.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.2;Leukemia: 23.9" "Testis - Spermatogonia" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Neutrophils: 577612.8;T-cells: 526897.2" "Group enriched" "Detected in some" 1311 "intestine: 96360.1;lymphoid tissue: 89285.9;salivary gland: 207752.3" "CAB000014, CAB016129" Enhanced Approved Vesicles NA NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 89: Adipocytes - Lipid metabolism" Vesicles "CAB000014: , CAB016129: " "unprognostic (4.72e-1)" "unprognostic (3.91e-2)" "unprognostic (1.42e-2)" "unprognostic (1.76e-2)" "unprognostic (5.92e-2)" "unprognostic (1.30e-2)" "unprognostic (2.37e-2)" "unprognostic (4.09e-2)" "unprognostic (5.02e-2)" "unprognostic (3.65e-2)" "unprognostic (9.27e-3)" "unprognostic (2.67e-1)" "unprognostic (1.76e-1)" "unprognostic (1.85e-2)" "unprognostic (9.78e-2)" "potential prognostic unfavorable (6.20e-6)" "unprognostic (8.26e-2)" "unprognostic (7.79e-2)" "unprognostic (2.40e-1)" "unprognostic (3.17e-1)" "unprognostic (2.37e-1)" "unprognostic (1.37e-2)" "unprognostic (1.35e-1)" "unprognostic (9.55e-2)" "unprognostic (1.28e-3)" "unprognostic (2.74e-1)" "unprognostic (6.75e-2)" "unprognostic (5.68e-2)" "unprognostic (2.98e-1)" "unprognostic (8.81e-2)" "unprognostic (6.55e-3)" FUT6 "FCT3A, FLJ40754, FT1A, FucT-VI" ENSG00000156413 "Fucosyltransferase 6" P51993 19 5830408-5839722 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 76.6;kidney: 32.8;salivary gland: 43.9" "Cell type enhanced" "Detected in many" "Colonocytes: 56.7;Enteric transient amplifying cells: 47.1;Enterocytes: 131.0;Esophageal apical cells: 517.5;Esophageal suprabasal cells: 48.8;Goblet cells: 89.4;Paneth cells: 54.1;Proximal tubule cells: 129.1;Respiratory secretory cells: 52.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 517.5;Enterocytes: 131.0;Renal nephron cells: 129.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "basophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "colorectal cancer: 7.9;Gastric cancer: 4.4" "Breast - Breast glandular cells (progenitors), Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 2, Prostate - Urothelial cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 63674 "intestine: 7188318.5;salivary gland: 5546554.7" "HPA043707, HPA046966" Approved Supported "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" "Golgi apparatus" "HPA043707: , HPA046966: " "unprognostic (5.67e-2)" "unprognostic (4.86e-2)" "unprognostic (2.88e-1)" "unprognostic (2.80e-2)" "unprognostic (7.24e-3)" "unprognostic (4.62e-2)" "potential prognostic favorable (3.21e-4)" "validated prognostic favorable (3.62e-9)" "validated prognostic favorable (2.18e-4)" "potential prognostic favorable (1.08e-5)" "unprognostic (1.33e-1)" "unprognostic (2.22e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (4.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-2)" "unprognostic (6.84e-3)" "unprognostic (3.02e-1)" "unprognostic (1.49e-2)" "unprognostic (4.28e-2)" FUT9 Fuc-TIX ENSG00000172461 "Fucosyltransferase 9" Q9Y231 6 96015974-96215612 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Carbohydrate metabolism, Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 16.0;stomach 1: 21.8" "Cell type enhanced" "Detected in many" "Astrocytes: 1171.8;Bergmann glia: 649.1;Brain excitatory neurons: 391.1;Brain inhibitory neurons: 426.3;Corticotrophs: 244.4;Ependymal cells: 565.8;Gastric chief cells: 597.4;Mucous neck cells: 1469.9;Oligodendrocyte progenitor cells: 246.8;Oligodendrocytes: 350.9;Parietal cells: 275.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 565.8;Gastric glandular cells: 1469.9;Glial cells: 1171.8;Neuronal cells: 426.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.8" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22911 "Microglia and Neuropil: 1096142.2;Neurons: 3486077.9" "Tissue enriched" "Detected in some" "cerebral cortex: 555248.5" HPA070923 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 27: Cerebellum - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 28: Astrocytes - Homeostasis & neuron support" 4 Nucleoplasm "Microtubules, Cytokinetic bridge, Cytosol" "HPA070923: " "unprognostic (3.52e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (6.92e-5)" "unprognostic (8.02e-2)" "unprognostic (4.82e-2)" FUZ "CPLANE3, FLJ22688, Fy" ENSG00000010361 "Fuzzy planar cell polarity protein" Q9BT04 19 49806866-49817376 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 76.2" "Group enriched" "Detected in many" 4 "Early spermatids: 1418.6;Late spermatids: 3322.5" "Cell type enriched" "Detected in all" 33 "Spermatogenic cell types: 3322.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 353486.2;Distal tubules: 1126122.9" "Not detected" "Not detected" "HPA041779, HPA042196" Approved Approved Cytosol No NA "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 8 Cytosol "HPA041779: , HPA042196: " "unprognostic (9.79e-2)" "unprognostic (3.58e-3)" "unprognostic (1.59e-1)" "unprognostic (4.81e-2)" "unprognostic (2.28e-1)" "unprognostic (4.42e-2)" "unprognostic (3.72e-2)" "unprognostic (2.91e-1)" "unprognostic (1.22e-2)" "unprognostic (2.85e-1)" "unprognostic (3.43e-3)" "unprognostic (5.58e-2)" "potential prognostic favorable (2.22e-5)" "unprognostic (2.23e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.36e-1)" "unprognostic (2.63e-3)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "unprognostic (6.62e-2)" "unprognostic (5.01e-2)" "unprognostic (8.19e-2)" "unprognostic (1.48e-1)" "unprognostic (1.69e-2)" "unprognostic (3.21e-2)" "unprognostic (2.98e-2)" "unprognostic (3.58e-3)" "unprognostic (2.95e-1)" "unprognostic (1.11e-1)" "unprognostic (2.06e-1)" FXN "CyaY, FA, FARR, FRDA, X25" ENSG00000165060 Frataxin Q16595 9 69035751-69079076 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Heme biosynthesis, Ion transport, Iron storage, Iron transport, Transport" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 7.9;Hepatocytes: 10.2;Megakaryocyte progenitors: 4.7;Megakaryocytes: 6.2;Oocytes: 13.8;Parietal cells: 10.6;Plasma cells: 4.7" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 10.6;Hepatocytes: 10.2;Oocytes: 13.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "heart muscle: 104408429.3" "CAB022164, HPA068304" Supported Supported Mitochondria,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 67: Plasma cells - Plasma cell differentiation" 10 Mitochondria Cytosol "CAB022164: , HPA068304: " "unprognostic (2.37e-2)" "unprognostic (9.61e-2)" "unprognostic (2.19e-1)" "unprognostic (1.29e-1)" "unprognostic (1.20e-1)" "unprognostic (2.03e-1)" "unprognostic (2.93e-2)" "unprognostic (7.55e-2)" "unprognostic (2.97e-2)" "unprognostic (3.82e-1)" "unprognostic (1.12e-2)" "unprognostic (3.13e-2)" "unprognostic (3.84e-1)" "unprognostic (1.70e-1)" "unprognostic (2.03e-1)" "unprognostic (2.39e-2)" "unprognostic (3.00e-1)" "unprognostic (1.80e-1)" "unprognostic (1.51e-2)" "unprognostic (2.21e-2)" "unprognostic (1.13e-2)" "unprognostic (6.02e-2)" "unprognostic (6.13e-2)" "unprognostic (2.50e-1)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (8.36e-2)" "unprognostic (1.65e-1)" "unprognostic (2.15e-1)" "unprognostic (1.52e-1)" "unprognostic (5.23e-2)" FXYD1 PLM ENSG00000266964 "FXYD domain containing ion transport regulator 1" O00168 19 35138824-35143109 "Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1674.5;skeletal muscle: 1295.2" "Group enriched" "Detected in some" 4 "Astrocytes: 115.8;Bergmann glia: 262.7" "Cell type enriched" "Detected in many" 6 "Glial cells: 262.7" "Cell type enhanced" "Detected in many" "astrocyte: 122.7;Bergmann glia: 336.8;choroid plexus epithelial cell: 106.5" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 222.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 11.1" "Group enriched" "Detected in many" 4 "B-cells: 11.1;T-cells: 6.9" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 6.9" "Breast - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatocytes, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 23160533.8;Cardiomyocytes: 26086129.3" "Group enriched" "Detected in many" "heart muscle: 35461230.7;liver: 12681579.0" HPA026873 Approved Nucleoplasm,Nucleoli,Cytosol No NA 54000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Nucleoplasm, Cytosol" Nucleoli "HPA026873: " "unprognostic (1.89e-3)" "unprognostic (1.36e-1)" "potential prognostic favorable (5.20e-4)" "potential prognostic favorable (5.06e-4)" "unprognostic (2.36e-1)" "unprognostic (2.41e-1)" "unprognostic (2.93e-3)" "unprognostic (7.78e-3)" "unprognostic (2.62e-2)" "unprognostic (5.12e-2)" "unprognostic (7.83e-2)" "unprognostic (4.54e-1)" "potential prognostic unfavorable (7.96e-6)" "unprognostic (2.85e-2)" "unprognostic (2.75e-2)" "potential prognostic favorable (5.04e-4)" "unprognostic (7.15e-2)" "unprognostic (3.89e-2)" "unprognostic (2.06e-1)" "unprognostic (2.99e-2)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (1.77e-3)" "unprognostic (1.49e-1)" "unprognostic (4.39e-2)" "unprognostic (3.07e-1)" "unprognostic (2.79e-2)" "unprognostic (6.29e-3)" "unprognostic (2.19e-1)" "unprognostic (3.86e-2)" "unprognostic (3.05e-1)" FYB2 "ARAP, C1orf168, FLJ43208, RP4-758N20.2" ENSG00000187889 "FYN binding protein 2" Q5VWT5 1 56718789-56819696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.6;fallopian tube: 12.9;liver: 16.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 234.1;Choroid plexus epithelial cells: 943.3;Epididymal clear cells: 381.7;Pituitary stem cells: 284.0;Renal collecting duct intercalated cells: 794.9;Renal collecting duct principal cells: 419.5;Renal connecting tubule cells: 264.6;Respiratory ciliated cells: 372.6;Respiratory ionocytes: 561.4;Respiratory secretory cells: 281.7;Retinal pigment epithelial cells: 567.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 943.3;Ductal cells: 794.9;Ionocytes: 561.4;Pigment cells: 567.0" "Cell type enriched" "Detected in many" 33 "choroid plexus epithelial cell: 702.3" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 6.3" "Region enriched" "Detected in some" 13 "choroid plexus: 31.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in single" "hippocampal formation: 2.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Collecting ducts: 365692.1;Fallopian tube cells: 567255.2" "Tissue enriched" "Detected in single" 745 "fallopian tube: 74477.6" HPA054923 Uncertain "Perinuclear theca,Mid piece,Principal piece" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Perinuclear theca, Mid piece, Principal piece" "HPA054923: " "unprognostic (6.46e-3)" "unprognostic (1.42e-1)" "unprognostic (1.57e-2)" "unprognostic (5.20e-3)" "unprognostic (4.85e-2)" "unprognostic (1.08e-1)" "unprognostic (2.12e-1)" FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 707.1;Bergmann glia: 770.9;Innate lymphoid cells: 1307.3;NK-cells: 1966.4;Oligodendrocyte progenitor cells: 609.8;Oligodendrocytes: 813.6;Podocytes: 1092.5;T-cells: 2000.5" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 1307.3;NK-cells: 1966.4;Renal nephron cells: 1092.5;T-cells: 2000.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 3021.6" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 182.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 17 "NK-cells: 69.0;T-cells: 174.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Endothelial cells, Breast - Endothelial cells, Lung - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 20082743.8;Microglia and Neuropil: 16581554.2" "Group enriched" "Detected in many" "cerebral cortex: 16796918.6;lung: 6078072.0;lymphoid tissue: 18722231.9" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Supported "Plasma membrane,Cytosol" NA NA 290000 "Cluster 1: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 141 "Plasma membrane" Cytosol "CAB005034: , CAB018387: , HPA023887: , HPA063770: " "unprognostic (3.58e-1)" "unprognostic (1.91e-2)" "unprognostic (9.86e-2)" "unprognostic (5.15e-2)" "unprognostic (1.91e-1)" "unprognostic (3.16e-2)" "unprognostic (1.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.72e-2)" "unprognostic (8.15e-2)" "validated prognostic favorable (1.08e-5)" "validated prognostic favorable (3.70e-5)" "unprognostic (8.27e-3)" "validated prognostic favorable (7.38e-4)" "validated prognostic favorable (5.08e-5)" "unprognostic (8.88e-3)" "unprognostic (1.04e-1)" "unprognostic (8.18e-3)" "unprognostic (7.02e-2)" "unprognostic (1.45e-2)" "unprognostic (6.71e-2)" "unprognostic (3.54e-3)" "unprognostic (1.36e-2)" "unprognostic (3.55e-1)" "unprognostic (4.15e-2)" "unprognostic (2.37e-1)" "unprognostic (4.90e-2)" "unprognostic (3.47e-2)" "unprognostic (6.87e-2)" "unprognostic (1.48e-2)" "unprognostic (1.92e-1)" FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 9.4;choroid plexus: 8.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;cDC: 11.6;Choroid plexus epithelial cells: 12.8;Fibroblasts: 11.7;Hepatic stellate cells: 12.9;Leydig cells: 45.3;Microglia: 14.1;Monocyte progenitors: 13.1;monocytes: 11.2;Peritubular myoid cells: 35.1;Podocytes: 17.0;Retinal pigment epithelial cells: 12.8" "Cell type enhanced" "Detected in many" "Alveolar cells: 28.9;Leydig cells: 45.3;Stromal cells: 35.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 16.0;choroid plexus epithelial cell: 14.4;fibroblast: 24.3" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 6 "choroid plexus: 21.1" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA057667 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Cell Junctions,Actin filaments,Basal body" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 94: Gonadal somatic cells - Mixed function" 1 "Nucleoplasm, Nuclear bodies, Cell Junctions" "Actin filaments, Basal body" "HPA057667: " "unprognostic (4.96e-2)" "unprognostic (3.28e-2)" "unprognostic (4.14e-1)" "unprognostic (3.76e-2)" "unprognostic (3.51e-2)" "unprognostic (3.07e-1)" "unprognostic (6.49e-2)" "unprognostic (1.20e-3)" "unprognostic (8.27e-3)" "unprognostic (3.20e-1)" "validated prognostic unfavorable (6.80e-5)" "validated prognostic unfavorable (9.98e-4)" "unprognostic (1.09e-1)" "unprognostic (1.36e-1)" "unprognostic (9.37e-2)" "unprognostic (1.82e-1)" "unprognostic (7.84e-3)" "unprognostic (9.78e-2)" "unprognostic (3.92e-1)" "unprognostic (6.39e-3)" "unprognostic (7.95e-2)" "unprognostic (1.56e-1)" "unprognostic (3.68e-1)" "unprognostic (4.58e-2)" "unprognostic (1.00e-1)" "unprognostic (5.16e-3)" "unprognostic (5.35e-2)" "unprognostic (7.95e-3)" "unprognostic (2.66e-2)" FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 112.7" "Cell type enhanced" "Detected in many" "Adipocytes: 189.5;Distal convoluted tubule cells: 78.1;Fibro-adipogenic progenitors: 53.6;Lymphatic endothelial cells: 43.1;Pituitary stem cells: 58.0;Renal connecting tubule cells: 65.7;Thymic myoid cells: 58.5;Vascular endothelial cells: 92.4" "Cell type enhanced" "Detected in many" "Adipocytes: 189.5;Endothelial cells: 92.4" "Cell type enriched" "Detected in many" 4 "endothelial cell: 83.6" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 42.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042328, HPA074833" Approved Supported "Nucleoplasm,Plasma membrane,Primary cilium" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 89: Adipocytes - Lipid metabolism" 7 "Plasma membrane" "Nucleoplasm, Primary cilium" "HPA042328: , HPA074833: " "unprognostic (5.42e-2)" "unprognostic (1.25e-1)" "unprognostic (6.24e-3)" "unprognostic (7.78e-3)" "unprognostic (2.34e-1)" "unprognostic (1.51e-2)" "unprognostic (1.76e-1)" "unprognostic (9.70e-3)" "unprognostic (1.11e-1)" "unprognostic (9.00e-2)" "validated prognostic favorable (1.58e-8)" "validated prognostic favorable (2.01e-4)" "potential prognostic favorable (5.49e-4)" "unprognostic (2.17e-1)" "unprognostic (1.96e-2)" "unprognostic (7.14e-3)" "unprognostic (2.49e-1)" "unprognostic (1.33e-2)" "unprognostic (2.56e-1)" "unprognostic (6.91e-2)" "unprognostic (2.83e-2)" "unprognostic (4.35e-2)" "unprognostic (1.49e-1)" "unprognostic (1.94e-1)" "unprognostic (4.97e-2)" "unprognostic (9.58e-2)" "unprognostic (3.70e-2)" "unprognostic (3.98e-3)" "unprognostic (1.98e-1)" "unprognostic (1.94e-1)" "unprognostic (3.56e-1)" FZD8 ENSG00000177283 "Frizzled class receptor 8" Q9H461 10 35638247-35642296 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 18.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 58.1;Breast myoepithelial cells: 21.5;Choroid plexus epithelial cells: 19.7;Hepatic stellate cells: 19.4;Müller glia: 32.5;Parietal cells: 37.1;Pituicytes/FSCs: 28.5;Podocytes: 19.4;Thymic myoid cells: 43.5" "Cell type enhanced" "Detected in many" "Alveolar cells: 58.1;Gastric glandular cells: 37.1;Glial cells: 32.5;Stromal cells: 43.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 23.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 85.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 45 "cerebral cortex: 4458.1" "HPA045025, HPA071142" Approved Approved "Endoplasmic reticulum,Primary cilium" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 3 "Endoplasmic reticulum" "Primary cilium" "HPA045025: , HPA071142: " "unprognostic (1.38e-1)" "unprognostic (7.58e-2)" "unprognostic (1.80e-2)" "unprognostic (1.21e-1)" "unprognostic (2.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "unprognostic (1.83e-1)" "unprognostic (1.77e-1)" "unprognostic (8.59e-2)" "unprognostic (2.15e-2)" "potential prognostic favorable (4.17e-5)" "unprognostic (2.27e-2)" "unprognostic (1.61e-1)" "unprognostic (6.95e-3)" "unprognostic (2.20e-1)" "unprognostic (2.17e-1)" "unprognostic (8.26e-3)" "unprognostic (1.87e-2)" "unprognostic (2.41e-1)" "unprognostic (3.28e-1)" "unprognostic (1.07e-3)" "potential prognostic favorable (8.99e-4)" "unprognostic (2.61e-1)" "unprognostic (8.46e-3)" "unprognostic (1.97e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-2)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (4.44e-4)" "unprognostic (7.89e-2)" G6PC3 UGRP ENSG00000141349 "Glucose-6-phosphatase catalytic subunit 3" Q9BUM1 17 44070620-44082151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Gluconeogenesis Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 204.7" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 204.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 136421.1" "Not detected" "Not detected" HPA067052 Supported "Endoplasmic reticulum" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 1 "Endoplasmic reticulum" "HPA067052: " "unprognostic (9.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.96e-1)" "unprognostic (1.84e-1)" "unprognostic (1.12e-1)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (7.29e-4)" "unprognostic (1.24e-2)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (1.20e-3)" "potential prognostic unfavorable (1.48e-4)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (4.15e-3)" "unprognostic (1.49e-1)" "unprognostic (3.13e-1)" "unprognostic (1.11e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-1)" "unprognostic (3.38e-1)" "unprognostic (6.64e-3)" "unprognostic (1.03e-2)" "unprognostic (1.03e-3)" "unprognostic (4.26e-1)" "unprognostic (1.37e-1)" "unprognostic (3.78e-1)" "unprognostic (1.94e-1)" "unprognostic (2.19e-1)" "unprognostic (5.57e-2)" "potential prognostic favorable (8.66e-4)" G6PD G6PD1 ENSG00000160211 "Glucose-6-phosphate dehydrogenase" P11413 X 154517825-154547572 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 135.2;Esophageal suprabasal cells: 163.7;Megakaryocytes: 136.0;Neutrophil progenitors: 148.2;Neutrophils: 141.1;Oocytes: 193.4;Platelets: 160.3" "Cell type enhanced" "Detected in many" "Oocytes: 193.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 383.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 383.4" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 839.6" "Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 333662472.4" "Low tissue specificity" "Detected in all" "HPA000247, HPA000834" Enhanced Supported "Centriolar satellite,Cytosol" No No 4900000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 Cytosol "Centriolar satellite" "HPA000247: , HPA000834: " "unprognostic (2.01e-1)" "unprognostic (1.42e-3)" "unprognostic (9.86e-2)" "unprognostic (2.30e-1)" "unprognostic (1.76e-1)" "unprognostic (5.92e-2)" "unprognostic (2.04e-1)" "unprognostic (2.31e-1)" "unprognostic (6.19e-2)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (6.84e-3)" "potential prognostic unfavorable (4.14e-5)" "validated prognostic unfavorable (2.01e-10)" "validated prognostic unfavorable (4.52e-5)" "unprognostic (7.26e-3)" "unprognostic (3.23e-1)" "unprognostic (9.07e-2)" "unprognostic (9.41e-2)" "unprognostic (1.27e-1)" "unprognostic (2.67e-2)" "unprognostic (2.07e-2)" "unprognostic (7.54e-2)" "unprognostic (2.85e-1)" "unprognostic (1.48e-1)" "unprognostic (6.44e-2)" "unprognostic (1.06e-1)" "unprognostic (2.36e-1)" "unprognostic (3.83e-2)" "unprognostic (4.47e-2)" "unprognostic (4.98e-2)" GABARAPL1 "APG8L, ATG8B, ATG8L, gec1" ENSG00000139112 "GABA type A receptor associated protein like 1" Q9H0R8 12 10212458-10223128 "Predicted intracellular proteins" "Autophagy, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 380.8;Syncytiotrophoblasts: 1337.8" "Cell type enriched" "Detected in all" 4 "Trophoblast cells: 1337.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 447.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 62.4" "Group enriched" "Detected in many" 5 "granulocytes: 62.4;NK-cells: 22.6;T-cells: 26.8" "Cancer enriched" "Detected in all" 5 "testis cancer: 513.0" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1219494.4" "Group enriched" "Detected in many" "fallopian tube: 236532.3;heart muscle: 210815.3" "HPA051386, HPA065883" Approved Supported "Vesicles,Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 129 Vesicles "Plasma membrane, Primary cilium, Basal body, Cytosol" "HPA051386: , HPA065883: " "unprognostic (3.63e-2)" "unprognostic (7.21e-2)" "unprognostic (4.65e-2)" "unprognostic (4.59e-1)" "unprognostic (2.63e-1)" "unprognostic (1.78e-3)" "unprognostic (9.14e-2)" "unprognostic (1.13e-2)" "unprognostic (5.85e-3)" "unprognostic (2.20e-1)" "validated prognostic favorable (8.56e-6)" "validated prognostic favorable (7.86e-5)" "unprognostic (1.92e-1)" "unprognostic (1.71e-3)" "unprognostic (3.43e-2)" "unprognostic (2.83e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "unprognostic (3.02e-1)" "unprognostic (1.27e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-1)" "unprognostic (4.76e-3)" "unprognostic (1.71e-1)" "unprognostic (3.85e-2)" "unprognostic (1.61e-2)" "unprognostic (1.30e-1)" "unprognostic (6.71e-3)" "unprognostic (9.94e-2)" "unprognostic (4.12e-2)" "unprognostic (2.94e-1)" GABRA1 EJM5 ENSG00000022355 "Gamma-aminobutyric acid type A receptor subunit alpha1" P14867 5 161847063-161899981 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "brain: 52.4;retina: 16.5" "Group enriched" "Detected in some" 7 "Brain excitatory neurons: 184.1;Brain inhibitory neurons: 156.6;Other brain neurons: 71.8;Retinal bipolar cells: 224.8" "Cell type enriched" "Detected in some" 10 "Neuronal cells: 224.8" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 583.1" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "breast cancer: 3.7" "Adrenal gland - Adrenal medulla cells, Skin - Inner root sheath cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 6249677.5;Microglia and Neuropil: 14913206.4;Neurons: 6970800.0" "Tissue enriched" "Detected in single" 289166 "cerebral cortex: 28916613.5" "CAB022502, HPA029363, HPA055746" Enhanced Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 14 "Plasma membrane" Nucleoplasm "CAB022502: , HPA029363: , HPA055746: " "unprognostic (1.08e-1)" "unprognostic (1.27e-1)" GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 37.3" "Cell type enhanced" "Detected in many" "Astrocytes: 448.7;Bergmann glia: 1024.6;Brain excitatory neurons: 186.5;Brain inhibitory neurons: 257.8;Other brain neurons: 199.3;Renal collecting duct principal cells: 98.4;Retinal amacrine cells: 228.2" "Group enriched" "Detected in many" 6 "Glial cells: 1024.6;Neuronal cells: 257.8" "Cell type enhanced" "Detected in all" "Bergmann glia: 1113.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 7.6" "Breast - Endothelial cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2156 "Astrocytes and Neuropil: 284319.1;Microglia and Neuropil: 284542.1;Neurons: 78054.2" "Tissue enriched" "Detected in single" 28673 "cerebral cortex: 2867332.5" "HPA029363, CAB079061" Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" Receptor NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (6.84e-2)" "unprognostic (6.00e-3)" "unprognostic (1.92e-2)" "unprognostic (3.72e-2)" "unprognostic (1.82e-1)" "unprognostic (1.36e-1)" "unprognostic (1.27e-3)" "unprognostic (1.22e-1)" GABRA3 ENSG00000011677 "Gamma-aminobutyric acid type A receptor subunit alpha3" P34903 X 152166234-152451315 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 16.4;choroid plexus: 32.1;retina: 8.3" "Cell type enhanced" "Detected in many" "Adipocytes: 36.1;Brain excitatory neurons: 54.7;Brain inhibitory neurons: 47.9;Choroid plexus epithelial cells: 223.9;Hofbauer cells: 98.4;Oligodendrocyte progenitor cells: 73.8;Other brain neurons: 61.6;Retinal amacrine cells: 57.3;Undifferentiated spermatogonia: 28.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 223.9;Glial cells: 73.8;Mononuclear phagocytes: 98.4;Neuronal cells: 61.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 26.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 80177 "Astrocytes and Neuropil: 5572828.7;Microglia and Neuropil: 10813884.7;Neurons: 7666380.4" "Tissue enriched" "Detected in single" 52368 "cerebral cortex: 5236774.8" "HPA000839, HPA029363" Approved Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Plasma membrane" Nucleoplasm "HPA000839: , HPA029363: " "unprognostic (1.26e-3)" "unprognostic (2.28e-1)" "unprognostic (7.92e-2)" "potential prognostic favorable (9.98e-5)" "unprognostic (1.63e-1)" "unprognostic (2.42e-1)" "unprognostic (2.37e-1)" "unprognostic (1.20e-1)" "unprognostic (1.94e-1)" "unprognostic (3.86e-2)" "unprognostic (2.21e-1)" "unprognostic (1.60e-3)" "unprognostic (5.85e-2)" GABRA5 ENSG00000186297 "Gamma-aminobutyric acid type A receptor subunit alpha5" P31644 15 26866911-26949208 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 121.7" "Cell type enriched" "Detected in some" 6 "Retinal bipolar cells: 381.5" "Cell type enriched" "Detected in some" 26 "Neuronal cells: 381.5" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Glioblastoma Multiforme (TCGA): 2.4;Lung Squamous Cell Carcinoma (TCGA): 1.4;Skin Cutaneous Melanoma (TCGA): 1.6;Testicular Germ Cell Tumor (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 22.0" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 1198378.8;Neurons: 307129.5" "Tissue enriched" "Detected in single" 6205 "cerebral cortex: 620549.7" "HPA029363, HPA077031, CAB079022" Supported Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Plasma membrane" "Nucleoplasm, Actin filaments, Cytosol" "CAB079022: , HPA029363: , HPA077031: " "unprognostic (1.45e-1)" "unprognostic (5.29e-2)" "unprognostic (9.13e-2)" "unprognostic (1.46e-1)" "unprognostic (4.71e-2)" GADD45GIP1 "CKBBP2, CKbetaBP2, CRIF1, MGC4667, MGC4758, PLINP-1, Plinp1, PRG6" ENSG00000179271 "GADD45G interacting protein 1" Q8TAE8 19 12953119-12957223 "Predicted intracellular proteins, Ribosomal proteins" "Cell cycle, Host-virus interaction" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 569.5;Esophageal suprabasal cells: 582.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Distal tubules: 796816.6;Fallopian tube cells: 1420888.8;Large ducts: 1208366.3;Pancreas epithelial cells: 508208.6;Proximal tubules: 426362.2" "Low tissue specificity" "Detected in many" "HPA055205, HPA065048, HPA071910" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 204 Mitochondria "HPA055205: , HPA065048: , HPA071910: " "unprognostic (2.11e-1)" "unprognostic (7.89e-2)" "unprognostic (8.22e-2)" "unprognostic (6.88e-2)" "unprognostic (4.22e-2)" "unprognostic (2.44e-1)" "unprognostic (2.88e-2)" "unprognostic (4.58e-1)" "unprognostic (1.98e-1)" "unprognostic (3.11e-1)" "unprognostic (1.58e-3)" "unprognostic (1.05e-2)" "unprognostic (5.48e-2)" "unprognostic (8.51e-3)" "unprognostic (1.13e-3)" "unprognostic (2.61e-2)" "unprognostic (4.43e-2)" "unprognostic (9.93e-3)" "unprognostic (2.12e-1)" "unprognostic (1.28e-3)" "unprognostic (5.18e-2)" "unprognostic (3.05e-1)" "unprognostic (1.81e-1)" "unprognostic (4.13e-2)" "unprognostic (3.24e-1)" "unprognostic (6.09e-2)" "unprognostic (2.20e-1)" "unprognostic (3.29e-1)" "unprognostic (5.63e-2)" "unprognostic (3.04e-2)" "unprognostic (1.02e-1)" GALNT11 GalNAc-T11 ENSG00000178234 "Polypeptide N-acetylgalactosaminyltransferase 11" Q8NCW6 7 152025674-152122340 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Notch signaling pathway" "Glycosyltransferase, Transferase" Heterotaxy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "choroid plexus: 799.6;kidney: 213.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1027.2;Retinal pigment epithelial cells: 443.3" "Cell type enhanced" "Detected in all" "Ciliated cells: 1027.2;Pigment cells: 443.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 876.7" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 271.2" "Region enriched" "Detected in all" 9 "choroid plexus: 878.7" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 24746971.2" "Tissue enriched" "Detected in single" 9750 "pancreas: 975046.5" "HPA039330, HPA074862" Uncertain Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytokinetic bridge,Primary cilium,Primary cilium tip,Basal body" Yes NA "Cluster 1: T-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "Cytokinetic bridge, Primary cilium, Primary cilium tip, Basal body" "HPA039330: , HPA074862: " "unprognostic (8.82e-2)" "unprognostic (1.66e-1)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.55e-1)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (1.95e-2)" "unprognostic (1.38e-1)" "unprognostic (9.63e-2)" "potential prognostic favorable (8.00e-8)" "unprognostic (3.65e-3)" "potential prognostic favorable (1.95e-7)" "unprognostic (1.69e-2)" "unprognostic (5.55e-2)" "unprognostic (1.04e-2)" "unprognostic (3.80e-1)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "unprognostic (1.35e-1)" "unprognostic (1.69e-1)" "unprognostic (3.90e-2)" "unprognostic (1.98e-2)" "unprognostic (2.14e-1)" "unprognostic (1.24e-1)" "unprognostic (9.58e-3)" "unprognostic (1.49e-1)" "unprognostic (4.43e-1)" "unprognostic (2.61e-1)" "unprognostic (7.90e-2)" "unprognostic (3.89e-2)" GALNT14 "FLJ12691, GalNac-T10, GalNac-T14" ENSG00000158089 "Polypeptide N-acetylgalactosaminyltransferase 14" Q96FL9 2 30910467-31155202 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 38.6" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 132.2;Distal convoluted tubule cells: 200.4;Esophageal apical cells: 337.0;Lactotrophs: 310.3;Loop of henle epithelial cells: 334.2;Neutrophil progenitors: 120.6;Neutrophils: 248.7;Ocular epithelial cells: 151.6;Proximal tubule cells: 656.4;Renal connecting tubule cells: 182.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 337.0;Neutrophils: 248.7;Pituitary endocrine cells: 310.3;Renal nephron cells: 656.4" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 361.5;midbrain-derived inhibitory: 754.6" "Group enriched" "Detected in many" 7 "Kidney Renal Clear Cell Carcinoma (TCGA): 117.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 97.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "neutrophil: 8.5" "Lineage enriched" "Detected in many" 8 "granulocytes: 8.5" "Cancer enriched" "Detected in many" 5 "Kidney cancer: 123.7" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Pancreatic islets: 1690398.1;Proximal tubules: 1063819.3" "Tissue enriched" "Detected in single" 11 "lymphoid tissue: 1064.9" HPA030138 Approved "Nucleoplasm,Golgi apparatus" NA NA 9200 "Cluster 20: Non-specific - DNA binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Golgi apparatus" Nucleoplasm "HPA030138: " "unprognostic (1.92e-2)" "unprognostic (7.90e-2)" "unprognostic (7.01e-2)" "unprognostic (1.62e-1)" "unprognostic (2.05e-3)" "potential prognostic favorable (1.07e-6)" "unprognostic (4.66e-3)" "unprognostic (2.00e-1)" "validated prognostic favorable (5.97e-10)" "validated prognostic favorable (2.96e-4)" "unprognostic (9.96e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (3.03e-3)" "unprognostic (6.76e-2)" "unprognostic (2.65e-1)" "unprognostic (7.67e-2)" "unprognostic (2.24e-1)" "unprognostic (1.62e-3)" "unprognostic (2.05e-3)" "unprognostic (2.07e-1)" "unprognostic (6.02e-2)" "unprognostic (1.12e-2)" "unprognostic (4.70e-2)" "unprognostic (2.58e-1)" "unprognostic (1.72e-2)" GALNT5 GalNAc-T5 ENSG00000136542 "Polypeptide N-acetylgalactosaminyltransferase 5" Q7Z7M9 2 157257705-157318491 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 12.7;lung: 9.6;stomach 1: 12.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 220.1;Choroid plexus epithelial cells: 91.7;Colonocytes: 84.8;Conjunctival goblet cells: 76.7;Endometrial secretory cells: 87.5;Esophageal apical cells: 92.6;Foveolar cells: 146.9;Goblet cells: 257.1;Lacrimal acinar cells: 79.7;Ocular epithelial cells: 104.7;Respiratory basal cells: 66.3;Respiratory deuterosomal cells: 81.9;Salivary basal cells: 102.4" "Cell type enhanced" "Detected in many" "Alveolar cells: 220.1;Gastric glandular cells: 146.9;Goblet cells: 257.1" "Group enriched" "Detected in some" 11 "choroid plexus epithelial cell: 69.9;upper rhombic lip: 75.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 7 "cerebellum: 8.9;choroid plexus: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 40.6" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" "Alveolar cell types: 2009911.4" "Tissue enhanced" "Detected in some" "salivary gland: 6240182.0" "HPA008963, HPA009035" Approved Approved "Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA 1100000 "Cluster 17: Intestine - Digestion" "Cluster 5: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 70: Intestinal goblet cells - Mucin production" 9 "Golgi apparatus, Cytosol" "Nucleoli, Vesicles" "HPA008963: , HPA009035: " "unprognostic (2.07e-1)" "unprognostic (2.91e-2)" "unprognostic (1.02e-1)" "unprognostic (6.67e-2)" "unprognostic (1.47e-1)" "unprognostic (4.11e-2)" "unprognostic (2.42e-3)" "unprognostic (3.60e-2)" "unprognostic (5.73e-2)" "unprognostic (9.02e-3)" "unprognostic (1.85e-1)" "unprognostic (8.10e-3)" "unprognostic (1.46e-1)" "unprognostic (8.57e-2)" "potential prognostic unfavorable (1.64e-5)" "unprognostic (9.69e-3)" "unprognostic (1.87e-2)" "unprognostic (1.38e-2)" "unprognostic (1.58e-2)" "unprognostic (3.42e-1)" "unprognostic (7.14e-2)" GAP43 "B-50, GAP-43, PP46" ENSG00000172020 "Growth associated protein 43" P17677 3 115623510-115721490 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Growth regulation, Neurogenesis" "Calmodulin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 36 "brain: 473.7" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 234.8;Brain inhibitory neurons: 148.6;Oligodendrocyte progenitor cells: 54.9;Other brain neurons: 248.7;Pituicytes/FSCs: 70.7;Retinal pigment epithelial cells: 81.0;Schwann cells: 33.2" "Group enriched" "Detected in many" 5 "Glial cells: 70.7;Neuronal cells: 248.7;Pigment cells: 81.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 45 "Glioblastoma Multiforme (TCGA): 579.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 8 "Neuroblastoma: 120.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 843812 "Astrocytes and Neuropil: 109640120.0;Microglia and Neuropil: 104231724.0;Neurons: 39271796.3" "Tissue enriched" "Detected in many" "cerebral cortex: 1191450768.8" "CAB004417, HPA013392, HPA015600, CAB078783" Enhanced Supported Enhanced "Plasma membrane" NA NA 29000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "Plasma membrane" "CAB004417: , CAB078783: , HPA013392: , HPA015600: " "unprognostic (1.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.05e-3)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.12e-2)" "unprognostic (2.91e-1)" "unprognostic (1.91e-1)" "unprognostic (6.80e-2)" "unprognostic (3.98e-3)" "unprognostic (4.18e-2)" "unprognostic (3.42e-2)" "unprognostic (4.79e-2)" "unprognostic (6.91e-2)" "unprognostic (2.79e-2)" GAPDH GAPD ENSG00000111640 "Glyceraldehyde-3-phosphate dehydrogenase" P04406 12 6534512-6538374 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Glycolysis, Immunity, Innate immunity, Translation regulation" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 25843.3;tongue: 17635.1" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 15050.4;Esophageal basal cells: 8938.4;Esophageal suprabasal cells: 9709.9;Extravillous trophoblasts: 13577.7;Migrating cytotrophoblasts: 8315.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 15050.4;Suprabasal cells: 9709.9;Trophoblast cells: 13577.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 5941277055.5" "Low tissue specificity" "Detected in all" "CAB005197, CAB016392, HPA040067, HPA061280, CAB079968" Supported Enhanced "Nuclear membrane,Vesicles,Plasma membrane,Cytosol" No No 810000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 148 "Plasma membrane, Cytosol" "Nuclear membrane, Vesicles" "CAB005197: , CAB016392: , CAB079968: , HPA040067: , HPA061280: " "unprognostic (2.72e-2)" "unprognostic (2.17e-1)" "unprognostic (1.38e-1)" "unprognostic (2.95e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (1.26e-2)" "unprognostic (5.08e-2)" "unprognostic (1.00e-3)" "unprognostic (2.31e-3)" "potential prognostic unfavorable (3.31e-5)" "unprognostic (2.74e-3)" "unprognostic (2.57e-2)" "validated prognostic unfavorable (3.95e-6)" "validated prognostic unfavorable (8.80e-10)" "validated prognostic unfavorable (1.61e-7)" "validated prognostic unfavorable (1.15e-5)" "unprognostic (8.44e-2)" "unprognostic (2.50e-1)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "unprognostic (4.63e-3)" "unprognostic (4.52e-2)" "unprognostic (2.01e-1)" "unprognostic (3.57e-1)" "unprognostic (1.46e-1)" "unprognostic (2.78e-1)" "unprognostic (9.28e-2)" "unprognostic (1.08e-1)" "unprognostic (1.38e-1)" "unprognostic (2.95e-3)" GAPDHS "GAPD2, GAPDH-2, GAPDS" ENSG00000105679 "Glyceraldehyde-3-phosphate dehydrogenase, spermatogenic" O14556 19 35533455-35545319 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "testis: 261.4" "Cell type enriched" "Detected in many" 6 "Late spermatids: 14190.3" "Cell type enriched" "Detected in many" 90 "Spermatogenic cell types: 14190.3" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 18 "Skin Cutaneous Melanoma (TCGA): 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA042666 Enhanced Approved "Nucleoplasm,Centrosome,Principal piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 79: Testis - Spermatogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 49 "Nucleoplasm, Principal piece" Centrosome "HPA042666: " "unprognostic (1.14e-2)" "unprognostic (1.43e-1)" "unprognostic (6.89e-2)" "unprognostic (2.96e-2)" "unprognostic (5.00e-2)" "unprognostic (8.03e-2)" "unprognostic (1.03e-1)" "unprognostic (4.67e-1)" "potential prognostic unfavorable (1.27e-7)" "unprognostic (3.63e-2)" "unprognostic (5.09e-2)" "unprognostic (2.58e-1)" "unprognostic (2.21e-1)" "unprognostic (3.44e-1)" "unprognostic (6.88e-3)" "unprognostic (2.09e-3)" "unprognostic (1.13e-1)" "unprognostic (9.57e-3)" "unprognostic (1.79e-3)" "unprognostic (4.73e-3)" "unprognostic (3.85e-1)" "unprognostic (2.65e-1)" "unprognostic (3.16e-1)" "unprognostic (3.48e-1)" "unprognostic (4.66e-2)" "unprognostic (2.18e-1)" GARNL3 "bA356B19.1, DKFZp761J1523" ENSG00000136895 "GTPase activating Rap/RanGAP domain like 3" Q5VVW2 9 127224265-127393660 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 177.1;Adrenal medulla cells: 265.9;Astrocytes: 221.2;Brain excitatory neurons: 203.5;Brain inhibitory neurons: 190.5;Cardiomyocytes: 221.4;Endometrial stromal cells: 235.5;Microglia: 181.0;Oligodendrocytes: 207.7;Pituitary stem cells: 197.8" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 265.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 7.4" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 511185.2;Microglia and Neuropil: 732626.0;Neurons: 757522.5" "Tissue enriched" "Detected in single" 3288 "cerebral cortex: 328789.5" "HPA028757, HPA074886" Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" Vesicles Nucleoplasm "HPA028757: , HPA074886: " "unprognostic (1.07e-2)" "unprognostic (1.73e-1)" "unprognostic (1.01e-1)" "unprognostic (4.49e-2)" "unprognostic (4.47e-3)" "unprognostic (2.80e-2)" "potential prognostic favorable (4.99e-11)" "unprognostic (1.50e-2)" "unprognostic (3.70e-1)" "potential prognostic favorable (8.68e-4)" "unprognostic (2.73e-1)" "unprognostic (3.49e-1)" "unprognostic (1.33e-3)" "unprognostic (9.81e-3)" "unprognostic (2.24e-1)" "unprognostic (3.15e-1)" "unprognostic (1.16e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (1.66e-1)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (7.09e-4)" GART "GARS-AIRS-GART, PGFT, PRGS" ENSG00000159131 "Phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase" P22102 21 33503931-33543491 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Ligase, Multifunctional enzyme, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 188.8;Epicardial cells: 141.0" "Cell type enhanced" "Detected in many" "Myocytes: 188.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA002119, HPA005779" Approved Approved Mitochondria,Cytosol NA NA 350000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 15 Cytosol Mitochondria "HPA002119: , HPA005779: " "unprognostic (2.44e-1)" "unprognostic (2.89e-2)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (6.12e-2)" "unprognostic (3.20e-1)" "unprognostic (7.58e-2)" "unprognostic (5.20e-2)" "unprognostic (5.69e-2)" "unprognostic (4.46e-2)" "potential prognostic favorable (3.72e-4)" "unprognostic (3.54e-1)" "unprognostic (5.05e-3)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (2.03e-3)" "unprognostic (2.09e-2)" "unprognostic (2.41e-1)" "unprognostic (2.93e-1)" "unprognostic (1.33e-1)" "unprognostic (2.83e-1)" "potential prognostic unfavorable (5.85e-4)" "unprognostic (2.45e-1)" "unprognostic (4.06e-3)" "unprognostic (1.85e-3)" "unprognostic (7.51e-2)" "unprognostic (6.82e-2)" "unprognostic (5.59e-2)" "unprognostic (1.73e-1)" "unprognostic (8.05e-2)" "unprognostic (2.29e-1)" GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813001 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 37.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 227.0;Gonadotrophs: 461.0;Hepatocytes: 291.4;Myonuclei: 744.7;Retinal ganglion cells: 173.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 291.4;Myocytes: 744.7;Pituitary endocrine cells: 461.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 14.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Myeloma: 64.1" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Pituitary gland - Gonadotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Glomeruli: 7640843.1" "Group enriched" "Detected in some" "liver: 1234735.9;Stomach: 982393.8" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 45: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: " "unprognostic (6.64e-2)" "unprognostic (3.78e-1)" "unprognostic (7.94e-2)" "unprognostic (1.37e-2)" "unprognostic (9.05e-2)" "unprognostic (1.57e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-1)" "unprognostic (1.32e-3)" "potential prognostic favorable (8.42e-4)" "unprognostic (3.41e-1)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (4.85e-2)" "unprognostic (6.56e-2)" "unprognostic (3.15e-3)" "unprognostic (4.01e-2)" "unprognostic (5.55e-2)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (4.24e-2)" "unprognostic (4.09e-1)" "unprognostic (1.92e-1)" "unprognostic (4.94e-2)" "unprognostic (6.51e-2)" "unprognostic (4.87e-2)" GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 176.2" "Cell type enhanced" "Detected in many" "cDC: 349.5;Choroid plexus epithelial cells: 331.6;Fibro-adipogenic progenitors: 699.2;Macrophages: 385.3;Mast cells: 319.8;monocytes: 603.5;Neutrophils: 740.1;Schwann cells: 526.3;Sertoli cells: 279.2" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 699.2;Glial cells: 526.3;Mononuclear phagocytes: 603.5;Neutrophils: 740.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Skin Cutaneous Melanoma (TCGA): 132.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.3" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.3" "Cancer enhanced" "Detected in many" "skin cancer: 129.9" "Adrenal gland - Macrophages, Breast - Fibroblasts, Colon - Enteric glia cells, Lung - Fibroblasts_2, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts, Skin - Keratinocyte (granular), Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 12766154.8;Microglia and Neuropil: 17977062.9;Neurons: 28553969.9" "Group enriched" "Detected in many" "bone marrow: 3973549.2;cerebral cortex: 3919662.3" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: , HPA064678: " "unprognostic (6.01e-2)" "unprognostic (3.30e-2)" "unprognostic (3.85e-2)" "unprognostic (1.95e-1)" "unprognostic (7.01e-2)" "unprognostic (4.06e-2)" "unprognostic (2.60e-1)" "unprognostic (1.54e-3)" "unprognostic (3.78e-2)" "unprognostic (2.69e-1)" "unprognostic (1.32e-1)" "unprognostic (2.72e-1)" "unprognostic (9.87e-2)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (9.01e-3)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (8.10e-2)" "unprognostic (4.22e-3)" "potential prognostic unfavorable (4.67e-5)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (7.22e-2)" "unprognostic (4.64e-2)" "unprognostic (2.42e-3)" "unprognostic (4.29e-2)" "unprognostic (1.09e-1)" "unprognostic (2.89e-1)" "unprognostic (1.21e-2)" "unprognostic (2.60e-1)" GATA6 ENSG00000141448 "GATA binding protein 6" Q92908 18 22169589-22202528 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Atrial septal defect, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 57.4;ovary: 70.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 380.3;Alveolar cells type 2: 202.0;Cardiomyocytes: 182.6;Foveolar cells: 183.6;Gastric chief cells: 156.2;Hepatic stellate cells: 161.4;Mesothelial cells: 209.5;Mucous neck cells: 285.3;Ovarian stromal cells: 151.3;Pancreatic duct cells: 141.1;Parietal cells: 297.0" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 380.3;Gastric glandular cells: 297.0" "Cell type enhanced" "Detected in some" "endothelial cell: 18.6;fibroblast: 17.7;vascular associated smooth muscle cell: 7.4" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 45.3" "Region enriched" "Detected in single" 7 "choroid plexus: 5.9" "Immune cell enriched" "Detected in single" 23 "basophil: 4.0" "Lineage enriched" "Detected in single" 23 "granulocytes: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Capillaries: 22438.2" "Group enriched" "Detected in some" "fallopian tube: 371870.6;lymphoid tissue: 181445.3" "CAB011581, HPA066629" Approved Supported Nucleoplasm Yes No "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 8: Immune cells - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Nucleoplasm "CAB011581: , HPA066629: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (1.97e-2)" "unprognostic (1.07e-1)" "unprognostic (8.16e-2)" "unprognostic (1.09e-2)" "unprognostic (4.94e-3)" "unprognostic (5.90e-3)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (2.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.74e-1)" "unprognostic (8.73e-2)" "unprognostic (1.44e-2)" "unprognostic (8.92e-2)" "unprognostic (7.38e-2)" "unprognostic (3.02e-2)" "unprognostic (1.57e-1)" "unprognostic (2.57e-2)" "unprognostic (3.15e-2)" "unprognostic (2.23e-2)" "unprognostic (7.52e-3)" "potential prognostic unfavorable (6.33e-4)" "unprognostic (1.01e-1)" "unprognostic (1.02e-1)" "unprognostic (3.44e-2)" "unprognostic (2.20e-2)" GATAD1 "FLJ22489, ODAG, RG083M05.2" ENSG00000157259 "GATA zinc finger domain containing 1" Q8WUU5 7 92447482-92460075 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 122.8" "Cell type enhanced" "Detected in many" "Glial cells: 122.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 605 "intestine: 81851.0;lymphoid tissue: 39094.9" "HPA006105, HPA072785" Enhanced Nucleoplasm Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 34 Nucleoplasm "HPA006105: , HPA072785: " "unprognostic (8.23e-3)" "unprognostic (3.71e-1)" "unprognostic (1.49e-1)" "unprognostic (4.41e-3)" "unprognostic (4.89e-2)" "unprognostic (1.84e-1)" "unprognostic (8.71e-2)" "unprognostic (1.17e-1)" "unprognostic (5.32e-2)" "unprognostic (2.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.07e-1)" "unprognostic (3.26e-2)" "unprognostic (4.00e-3)" "unprognostic (9.87e-2)" "unprognostic (1.06e-1)" "unprognostic (5.90e-2)" "unprognostic (3.47e-2)" "unprognostic (9.02e-2)" "unprognostic (1.21e-1)" "unprognostic (7.63e-2)" "unprognostic (1.95e-1)" "unprognostic (8.53e-3)" "unprognostic (2.98e-1)" "unprognostic (2.15e-1)" "unprognostic (8.49e-2)" "unprognostic (1.11e-2)" "unprognostic (1.97e-1)" "unprognostic (1.13e-1)" "unprognostic (2.73e-2)" "unprognostic (1.54e-3)" GATM AGAT ENSG00000171766 "Glycine amidinotransferase" P50440 15 45361124-45402327 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "kidney: 1959.8;liver: 2621.4;pancreas: 2768.2" "Group enriched" "Detected in many" 5 "Granulosa cells: 630.1;Hepatocytes: 1859.5;Pancreatic acinar cells: 1024.7" "Group enriched" "Detected in all" 5 "Acinar cells: 1024.7;Hepatocytes: 1859.5;Reproductive supporting cells: 630.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 227.1" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 487.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 11.1;myeloid DC: 6.6;naive B-cell: 5.4;plasmacytoid DC: 6.8" "Group enriched" "Detected in many" 5 "B-cells: 11.1;dendritic cells: 6.8" "Cancer enriched" "Detected in all" 4 "Rhabdoid: 180.4" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 1135983054.1;Pancreas epithelial cells: 3638553861.7;Pancreatic islets: 3262723239.4;Proximal tubules: 3264416042.9" "Tissue enriched" "Detected in all" "pancreas: 2955156470.9" HPA026077 Enhanced Supported Mitochondria NA NA 930000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 70: Non-specific - Protein processing" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 10 Mitochondria "HPA026077: " "unprognostic (6.46e-2)" "unprognostic (6.23e-2)" "unprognostic (1.94e-1)" "unprognostic (8.60e-2)" "unprognostic (1.00e-1)" "unprognostic (2.76e-1)" "unprognostic (2.05e-1)" "unprognostic (4.45e-2)" "unprognostic (6.80e-2)" "unprognostic (1.52e-1)" "validated prognostic favorable (4.33e-10)" "validated prognostic favorable (3.22e-6)" "unprognostic (2.94e-3)" "unprognostic (1.46e-2)" "unprognostic (7.87e-3)" "unprognostic (1.14e-1)" "unprognostic (4.36e-1)" "unprognostic (1.44e-1)" "unprognostic (1.21e-1)" "unprognostic (5.68e-2)" "unprognostic (2.13e-1)" "unprognostic (8.63e-2)" "unprognostic (2.05e-2)" "unprognostic (1.11e-1)" "unprognostic (2.29e-1)" "unprognostic (4.57e-2)" "unprognostic (4.13e-2)" "unprognostic (1.50e-1)" "unprognostic (2.32e-1)" "unprognostic (3.06e-2)" "unprognostic (3.98e-2)" GBX2 ENSG00000168505 "Gastrulation brain homeobox 2" P52951 2 236165236-236168386 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "brain: 2.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.1;Early spermatids: 3.6;Ependymal cells: 2.2;Other brain neurons: 2.7;Undifferentiated spermatogonia: 1.1" "Group enriched" "Detected in some" 5 "Ciliated cells: 2.2;Glial cells: 4.1;Neuronal cells: 2.7;Spermatogenic cell types: 3.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 5.9;ependymal cell: 3.6;thalamic excitatory: 13.9" "Group enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 2.7;Testicular Germ Cell Tumor (TCGA): 10.6" "Region enhanced" "Detected in many" "thalamus: 31.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 11.1" "Region enhanced" "Detected in single" "thalamus: 1.3" "Group enriched" "Detected in some" 4 "midbrain: 3.3;pons: 3.5;thalamus: 8.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA067809 Approved Nucleoplasm Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "HPA067809: " "unprognostic (9.29e-3)" "unprognostic (1.21e-2)" "unprognostic (3.79e-2)" GCAT KBL ENSG00000100116 "Glycine C-acetyltransferase" O75600 22 37807905-37817176 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 132.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 151.3;Hepatocytes: 74.3;Oocytes: 211.8;Pancreatic acinar cells: 74.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 151.3;Oocytes: 211.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 38180876.4;Pancreatic islets: 18686701.5" "Group enriched" "Detected in many" "heart muscle: 2448958.6;liver: 7788955.6;pancreas: 8443678.3" "HPA020460, HPA063924" Approved Supported "Nucleoplasm,Nuclear speckles,Mitochondria" Yes No "Cluster 11: T-cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 84: Apical squamous epithelium - Cornification" 21 "Nuclear speckles" "Nucleoplasm, Mitochondria" "HPA020460: , HPA063924: " "unprognostic (2.65e-1)" "unprognostic (3.36e-1)" "potential prognostic unfavorable (3.15e-4)" "unprognostic (2.69e-1)" "unprognostic (6.21e-2)" "unprognostic (1.75e-1)" "unprognostic (4.76e-2)" "unprognostic (4.14e-2)" "unprognostic (2.60e-2)" "unprognostic (4.20e-3)" "unprognostic (3.46e-2)" "unprognostic (3.01e-2)" "potential prognostic favorable (3.20e-4)" "unprognostic (1.94e-1)" "unprognostic (1.77e-1)" "unprognostic (1.20e-1)" "unprognostic (7.76e-2)" "unprognostic (5.52e-3)" "unprognostic (1.50e-1)" "unprognostic (2.25e-2)" "unprognostic (2.88e-1)" "unprognostic (3.28e-1)" "unprognostic (2.22e-1)" "unprognostic (2.77e-1)" "unprognostic (1.93e-3)" "unprognostic (1.45e-1)" "unprognostic (2.35e-2)" "unprognostic (2.12e-1)" "unprognostic (1.99e-1)" "unprognostic (8.03e-3)" "unprognostic (2.57e-1)" GCG "GLP-1, GLP1, GLP2, GRPP" ENSG00000115263 Glucagon P01275 2 162142882-162152404 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "pancreas: 1834.3" "Cell type enriched" "Detected in some" 19 "Pancreatic islet cells: 80427.5" "Cell type enriched" "Detected in some" 19 "Pancreatic islet cells: 80427.5" "Cell type enriched" "Detected in single" 10 "midbrain-derived inhibitory: 1.7" "Cancer enriched" "Detected in some" 167 "Pancreatic Adenocarcinoma (TCGA): 1477.8" "Region enriched" "Detected in single" 51 "medulla oblongata: 13.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 114.8;Rhabdoid: 411.9" "Colon - Colon enterocytes, Pancreas - Alpha cells" "Region enriched" "Detected in single" 10 "pons and medulla: 3.5" "Region enriched" "Detected in some" 5 "spinal cord: 18.2" "Cell type enriched" "Detected in some" "Pancreatic islets: 66476161.9" "Tissue enriched" "Detected in some" "pancreas: 55686025.3" "CAB000040, HPA036760, HPA036761" Enhanced Approved "Endoplasmic reticulum,Vesicles" "Secreted to blood" Hormone NA NA 127000 130000 "Cluster 8: Pancreas - Proteolysis" "Cluster 43: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 10 "Endoplasmic reticulum" Vesicles "CAB000040: , HPA036760: , HPA036761: " "unprognostic (8.67e-2)" "unprognostic (1.82e-1)" "unprognostic (6.19e-2)" "unprognostic (3.55e-1)" "unprognostic (2.19e-1)" "unprognostic (3.71e-3)" "unprognostic (2.83e-2)" GCLC "GCS, GLCL, GLCLC" ENSG00000001084 "Glutamate-cysteine ligase catalytic subunit" P48506 6 53497341-53616970 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 142.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 298.6;Neuroendocrine cells: 358.7;Prostatic hillock cells: 342.1;Respiratory ciliated cells: 305.6;Urothelial cells: 1133.8" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 1133.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Lung Squamous Cell Carcinoma (TCGA): 163.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 4.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 429.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate basal glandular cells, Spleen - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fallopian tube cells: 59730316.8;Hepatocytes: 62155483.6" "Low tissue specificity" "Detected in all" "CAB009569, HPA036359, HPA036360" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 6400000 "Cluster 41: Basophils - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 69: Urothelial cells - Basic cellular functions" 7 Nucleoplasm "Nucleoli, Cytosol" "CAB009569: , HPA036359: , HPA036360: " "unprognostic (5.35e-2)" "unprognostic (2.25e-2)" "unprognostic (1.62e-1)" "unprognostic (1.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (1.15e-1)" "unprognostic (2.03e-1)" "unprognostic (6.10e-3)" "potential prognostic favorable (1.50e-7)" "unprognostic (1.19e-3)" "potential prognostic unfavorable (6.65e-4)" "unprognostic (3.77e-1)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (8.89e-4)" "unprognostic (7.22e-2)" "unprognostic (2.99e-1)" "unprognostic (6.42e-2)" "unprognostic (2.27e-1)" "unprognostic (1.72e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-2)" "potential prognostic favorable (9.49e-4)" "unprognostic (3.34e-1)" "unprognostic (2.33e-3)" "unprognostic (3.17e-1)" "unprognostic (2.07e-1)" "unprognostic (3.39e-2)" "unprognostic (1.37e-1)" GCLM GLCLR ENSG00000023909 "Glutamate-cysteine ligase modifier subunit" P48507 1 93885199-93909456 "Cancer-related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 45.3" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 260.4;Epididymal clear cells: 308.2;Epididymal efferent duct ciliated cells: 453.7;Erythrocyte progenitors: 274.0" "Cell type enhanced" "Detected in all" "Ciliated cells: 453.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in all" 9 "Gallbladder cancer: 586.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "bone marrow: 39718172.2" "CAB009568, HPA023696, CAB040554" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 1: T-cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009568: , CAB040554: , HPA023696: " "unprognostic (2.10e-2)" "unprognostic (2.95e-1)" "unprognostic (1.50e-1)" "unprognostic (8.65e-2)" "potential prognostic favorable (6.29e-4)" "unprognostic (1.27e-1)" "unprognostic (5.64e-3)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (7.72e-2)" "unprognostic (2.73e-2)" "potential prognostic favorable (1.34e-4)" "unprognostic (2.00e-2)" "potential prognostic unfavorable (7.37e-4)" "potential prognostic unfavorable (1.14e-5)" "unprognostic (6.77e-2)" "unprognostic (9.85e-3)" "unprognostic (1.42e-1)" "unprognostic (5.56e-2)" "unprognostic (3.70e-1)" "unprognostic (3.50e-1)" "unprognostic (1.33e-1)" "unprognostic (1.08e-1)" "unprognostic (1.40e-1)" "unprognostic (1.05e-1)" "unprognostic (8.69e-2)" "unprognostic (2.30e-1)" "unprognostic (3.16e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-1)" "unprognostic (4.60e-2)" "unprognostic (5.64e-2)" GCNT2 "bA360O19.2, bA421M1.1, CCAT, GCNT5, IGNT, II, NACGT1, NAGCT1, ULG3" ENSG00000111846 "Glucosaminyl (N-acetyl) transferase 2 (I blood group)" Q8N0V5 6 10492223-10629368 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.7" "Group enriched" "Detected in many" 6 "Choroid plexus epithelial cells: 398.4;Distal convoluted tubule cells: 445.5;Loop of henle epithelial cells: 265.8;Microglia: 243.6;Oocytes: 548.0;Proximal tubule cells: 163.1;Renal collecting duct intercalated cells: 196.6;Renal connecting tubule cells: 145.2" "Group enriched" "Detected in many" 12 "Ciliated cells: 398.4;Ductal cells: 196.6;Glial cells: 243.6;Oocytes: 548.0;Renal nephron cells: 445.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 285.1;choroid plexus epithelial cell: 310.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 17.5;testis cancer: 19.4" "Adrenal gland - Endothelial cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Region enriched" "Detected in all" 4 "basal ganglia: 61.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 8799 "heart muscle: 879865.1" HPA026776 Approved Approved "Golgi apparatus" No No 570000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Golgi apparatus" "HPA026776: " "unprognostic (1.87e-1)" "unprognostic (2.58e-1)" "unprognostic (1.67e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (1.22e-1)" "unprognostic (3.69e-1)" "unprognostic (1.26e-1)" "potential prognostic favorable (2.43e-6)" "unprognostic (1.80e-2)" "unprognostic (1.09e-1)" "unprognostic (1.57e-1)" "unprognostic (1.12e-1)" "unprognostic (2.41e-1)" "unprognostic (5.73e-2)" "unprognostic (2.29e-1)" "unprognostic (3.63e-2)" "unprognostic (5.79e-2)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.85e-4)" "unprognostic (6.29e-2)" "unprognostic (2.48e-2)" "unprognostic (4.05e-2)" "unprognostic (1.80e-1)" "unprognostic (1.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.55e-1)" GCNT3 "C2/4GnT, C2GnT-M, C2GnT2" ENSG00000140297 "Glucosaminyl (N-acetyl) transferase 3, mucin type" O95395 15 59594875-59640239 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 71.0;intestine: 133.9;salivary gland: 54.3" "Cell type enhanced" "Detected in many" "Colonocytes: 268.9;Conjunctival goblet cells: 133.0;Endometrial glandular cells: 163.2;Endometrial luminal cells: 83.6;Enteric transient amplifying cells: 68.5;Enterocytes: 179.7;Esophageal apical cells: 146.9;Foveolar cells: 82.9;Gastric progenitor cells: 85.9;Oocytes: 87.5;Papillary tip epithelial cells: 74.2;Renal collecting duct principal cells: 127.4;Salivary acinar cells: 86.8;Salivary duct cells: 113.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 146.9;Ductal cells: 127.4;Enterocytes: 268.9;Glandular cells: 163.2;Goblet cells: 133.0" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Pancreatic Adenocarcinoma (TCGA): 107.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 52.0;pancreatic cancer: 51.3" "Colon - Colon enterocytes, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2983 "Large ducts: 470572.1;Pancreas epithelial cells: 125939.5" "Tissue enriched" "Detected in single" 108126 "salivary gland: 10812588.0" HPA011154 Enhanced Approved "Golgi apparatus,Vesicles" NA NA "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 6 "Golgi apparatus" Vesicles "HPA011154: " "unprognostic (1.34e-1)" "unprognostic (1.68e-1)" "unprognostic (3.11e-2)" "unprognostic (9.87e-3)" "unprognostic (6.50e-2)" "unprognostic (1.96e-1)" "unprognostic (1.48e-2)" "unprognostic (1.00e-1)" "unprognostic (1.52e-1)" "unprognostic (1.09e-2)" "unprognostic (6.37e-3)" "validated prognostic unfavorable (3.52e-5)" "validated prognostic unfavorable (4.09e-4)" "unprognostic (3.42e-3)" "unprognostic (7.85e-2)" "unprognostic (1.46e-2)" "unprognostic (3.86e-1)" "unprognostic (1.96e-1)" "unprognostic (1.40e-1)" "unprognostic (1.92e-2)" "unprognostic (3.01e-1)" "unprognostic (2.22e-1)" "unprognostic (1.65e-2)" "unprognostic (1.36e-1)" "unprognostic (2.84e-2)" "unprognostic (5.27e-2)" "unprognostic (1.71e-2)" GCNT4 "C2GNT3, LINC01336" ENSG00000176928 "Glucosaminyl (N-acetyl) transferase 4" Q9P109 5 75025346-75052558 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 22.6;lymphoid tissue: 14.4;stomach 1: 17.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.1;Endometrial luminal cells: 44.2;Enterocytes: 40.3;Foveolar cells: 114.0;Mast cells: 48.8;Mucous neck cells: 65.6;Parietal cells: 77.8;Syncytiotrophoblasts: 44.2" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 114.0;Trophoblast cells: 71.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 22.5" "Group enriched" "Detected in many" 54 "granulocytes: 22.5;T-cells: 18.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 8.7;testis cancer: 6.5" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 272446.0;Distal tubules: 86823.0;Pancreatic islets: 209712.3" "Not detected" "Not detected" HPA037431 Approved Supported "Nucleoplasm,Golgi apparatus" No NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Golgi apparatus" Nucleoplasm "HPA037431: " "unprognostic (3.82e-1)" "unprognostic (1.07e-1)" "unprognostic (3.67e-1)" "potential prognostic favorable (3.55e-4)" "unprognostic (1.59e-1)" "unprognostic (1.60e-1)" "unprognostic (2.81e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (3.52e-7)" "unprognostic (4.17e-2)" "unprognostic (3.20e-2)" "unprognostic (4.14e-3)" "unprognostic (1.26e-1)" "unprognostic (7.09e-2)" "unprognostic (7.43e-2)" "unprognostic (4.55e-2)" "potential prognostic favorable (5.11e-4)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (8.13e-2)" "unprognostic (7.46e-2)" GCSAML "C1orf150, FLJ44728" ENSG00000169224 "Germinal center associated signaling and motility like" Q5JQS6 1 247507058-247577690 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.9;prostate: 5.1" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 23.8;Hematopoietic stem cells: 44.6;Late primary spermatocytes: 29.9;Mast cells: 228.9;Megakaryocyte progenitors: 66.0;Megakaryocytes: 117.5;Platelets: 82.9;Prostatic glandular cells: 57.1" "Cell type enhanced" "Detected in many" "Glandular cells: 57.1;Mast cells: 228.9;Megakaryocytes: 117.5;Platelets: 82.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 4.9;upper rhombic lip: 13.2" "Cancer enriched" "Detected in single" 7 "Prostate Adenocarcinoma (TCGA): 3.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 670 "basophil: 228.8" "Lineage enriched" "Detected in single" 670 "granulocytes: 228.8" "Cancer enriched" "Detected in some" 13 "Leukemia: 24.5" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Lung - Mast cells, Minor Salivary Gland - Mast cells, Prostate - Prostate glandular cells, Skin - Mast cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "intestine: 140357.0" "HPA027507, HPA027510" Uncertain Approved Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 7 Cytosol "HPA027507: , HPA027510: " "unprognostic (4.10e-3)" "unprognostic (1.35e-1)" "unprognostic (2.25e-2)" "unprognostic (3.17e-2)" "unprognostic (7.07e-3)" GDA "CYPIN, GAH" ENSG00000119125 "Guanine deaminase" Q9Y2T3 9 72114595-72257193 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 69.9;intestine: 89.3;kidney: 40.1;liver: 57.4" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 906.4;Endometrial glandular cells: 1151.2;Endometrial luminal cells: 2092.8;Endometrial secretory cells: 843.6;Enterocytes: 1690.7" "Group enriched" "Detected in many" 4 "Ciliated cells: 906.4;Enterocytes: 1690.7;Glandular cells: 1151.2;Luminal cells: 2092.8;Secretory cells: 843.6" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 279.5;hippocampal CA1-3: 266.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 69.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "amygdala: 50.6;basal ganglia: 42.2;cerebral cortex: 84.8;hippocampal formation: 98.5;olfactory bulb: 26.5" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 182570604.2;Glomeruli: 140999286.6;Microglia and Neuropil: 148914534.7" "Tissue enhanced" "Detected in many" "cerebral cortex: 383626933.7" "HPA019352, HPA024099, HPA030387" Enhanced Approved Nucleoplasm No NA 2100000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 3 Nucleoplasm "HPA019352: , HPA024099: , HPA030387: " "unprognostic (7.44e-2)" "unprognostic (6.27e-2)" "unprognostic (6.71e-2)" "unprognostic (6.19e-2)" "unprognostic (1.70e-2)" "unprognostic (9.81e-2)" "unprognostic (2.64e-1)" "unprognostic (9.35e-3)" "potential prognostic favorable (5.57e-6)" "unprognostic (2.35e-2)" "unprognostic (1.16e-2)" "unprognostic (6.74e-2)" "unprognostic (1.37e-2)" "unprognostic (3.23e-2)" "unprognostic (5.19e-2)" "unprognostic (3.68e-2)" "unprognostic (2.30e-3)" "unprognostic (1.64e-1)" "unprognostic (1.02e-2)" "unprognostic (1.52e-1)" "unprognostic (4.24e-1)" "unprognostic (1.06e-1)" "unprognostic (2.04e-1)" "unprognostic (1.48e-1)" "unprognostic (8.51e-2)" "unprognostic (1.35e-1)" GDAP2 "dJ776P7.1, FLJ20142, MACROD3" ENSG00000196505 "Ganglioside induced differentiation associated protein 2" Q9NXN4 1 117863485-117929621 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 137.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1605735.8" "Tissue enriched" "Detected in many" "bone marrow: 6146975.9" HPA046185 Approved Approved "Endoplasmic reticulum" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 "Endoplasmic reticulum" "HPA046185: " "unprognostic (2.86e-2)" "unprognostic (7.25e-2)" "unprognostic (2.34e-1)" "unprognostic (2.42e-1)" "unprognostic (2.58e-2)" "unprognostic (2.60e-2)" "unprognostic (3.55e-1)" "unprognostic (1.45e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.69e-5)" "potential prognostic favorable (7.65e-5)" "unprognostic (3.68e-2)" "unprognostic (1.19e-1)" "unprognostic (1.70e-3)" "unprognostic (1.26e-2)" "unprognostic (8.04e-2)" "unprognostic (5.03e-2)" "unprognostic (2.24e-2)" "unprognostic (3.83e-1)" "unprognostic (2.55e-2)" "unprognostic (7.82e-2)" "unprognostic (1.44e-3)" "unprognostic (2.79e-2)" "unprognostic (6.35e-3)" "unprognostic (1.03e-2)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (8.49e-2)" "unprognostic (5.29e-2)" "unprognostic (1.72e-2)" "unprognostic (8.66e-3)" GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501693-19522123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Syncytiotrophoblasts: 443.8" "Cell type enriched" "Detected in all" 4 "Trophoblast cells: 443.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 22747121.1" "Tissue enriched" "Detected in many" "cerebral cortex: 246285.7" HPA077420 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 11: White matter - Signal transduction" "Cluster 54: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 7 Vesicles "Nucleoplasm, Plasma membrane" "HPA077420: " "unprognostic (1.08e-1)" "unprognostic (2.43e-2)" "unprognostic (1.57e-1)" "unprognostic (2.83e-2)" "unprognostic (2.63e-2)" "unprognostic (1.66e-3)" "unprognostic (6.11e-2)" "unprognostic (1.82e-2)" "unprognostic (1.11e-2)" "unprognostic (1.48e-1)" "unprognostic (1.19e-1)" "unprognostic (5.61e-3)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (2.87e-5)" "unprognostic (3.71e-2)" "unprognostic (2.74e-2)" "unprognostic (2.77e-1)" "unprognostic (9.16e-2)" "unprognostic (4.33e-1)" "unprognostic (1.90e-1)" "unprognostic (2.80e-3)" "unprognostic (6.86e-3)" "unprognostic (1.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.21e-1)" "unprognostic (1.38e-2)" "unprognostic (2.21e-2)" "unprognostic (1.47e-2)" "unprognostic (2.11e-1)" "unprognostic (1.13e-1)" "unprognostic (5.22e-3)" GDF10 BMP-3b ENSG00000266524 "Growth differentiation factor 10" P55107 10 47300197-47313577 "Plasma proteins, Predicted secreted proteins" Osteogenesis "Cytokine, Growth factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 17.3;retina: 17.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 53.2;Bergmann glia: 44.7;Fibroblasts: 21.8;Retinal amacrine cells: 7.6;Retinal bipolar cells: 14.0;Rod photoreceptor cells: 22.1;Schwann cells: 20.3" "Group enriched" "Detected in some" 5 "Adrenal endocrine cells: 53.2;Fibroblasts: 21.8;Glial cells: 44.7;Neuronal cells: 22.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 44.6;midbrain-derived inhibitory: 15.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 24 "Bone cancer: 13.5" "Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Fibroblasts" "Region enriched" "Detected in all" 8 "cerebellum: 42.5" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Pancreas epithelial cells: 826385.4;Smooth muscle cells: 294687.2" "Group enriched" "Detected in some" 52138 "blood vessel: 3750321.5;lymphoid tissue: 6677211.8" HPA015498 Uncertain Approved Vesicles "Secreted in other tissues" Cytokine NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA015498: " "unprognostic (3.16e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (2.93e-5)" "unprognostic (1.71e-2)" "unprognostic (8.76e-2)" "unprognostic (3.68e-1)" "unprognostic (2.42e-1)" "unprognostic (1.57e-3)" GDI1 "FLJ41411, GDIL, MRX41, MRX48, OPHN2, RABGDIA, XAP-4" ENSG00000203879 "GDP dissociation inhibitor 1" P31150 X 154436913-154443467 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 501.7" "Cell type enhanced" "Detected in many" "Oocytes: 147.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 473662465.0;Microglia and Neuropil: 400524054.1;Neurons: 279005050.1;Oocytes: 198327218.0" "Tissue enriched" "Detected in all" "cerebral cortex: 863791073.7" "CAB012979, HPA049290, HPA057668" Enhanced Supported "Plasma membrane,Cytosol" NA NA 32000000 "Cluster 45: Eosinophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 80: Oligodendrocytes - Myelination" 112 Cytosol "Plasma membrane" "CAB012979: , HPA049290: , HPA057668: " "unprognostic (9.34e-2)" "potential prognostic unfavorable (6.13e-6)" "unprognostic (1.33e-1)" "unprognostic (5.65e-1)" "unprognostic (1.00e-2)" "potential prognostic unfavorable (1.72e-4)" "unprognostic (3.69e-1)" "unprognostic (6.63e-2)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (3.18e-2)" "potential prognostic favorable (1.89e-4)" "unprognostic (3.23e-1)" "unprognostic (3.49e-1)" "unprognostic (2.24e-3)" "unprognostic (5.02e-2)" "unprognostic (2.49e-2)" "unprognostic (1.28e-2)" "unprognostic (7.06e-2)" "unprognostic (2.31e-1)" "unprognostic (4.92e-2)" "unprognostic (1.13e-3)" "unprognostic (1.07e-3)" "unprognostic (2.36e-2)" "unprognostic (6.46e-2)" "unprognostic (1.78e-1)" "unprognostic (3.73e-1)" "unprognostic (3.51e-2)" "unprognostic (3.80e-1)" "unprognostic (5.44e-2)" "unprognostic (1.57e-1)" "unprognostic (1.31e-1)" GDI2 RABGDIB ENSG00000057608 "GDP dissociation inhibitor 2" P50395 10 5765223-5842132 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 851.9" "Cell type enhanced" "Detected in all" "Oocytes: 851.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA049290, HPA057668" Supported Approved "Plasma membrane,Cytosol" NA NA 43000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 52: Non-specific - Mitochondria" "Cluster 82: Dendritic cells - Antigen presentation" 80 "Plasma membrane, Cytosol" "HPA049290: , HPA057668: " "unprognostic (2.17e-1)" "unprognostic (6.20e-3)" "unprognostic (4.24e-1)" "unprognostic (1.44e-2)" "unprognostic (3.72e-2)" "unprognostic (4.67e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (2.96e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "potential prognostic favorable (1.19e-9)" "unprognostic (4.64e-2)" "unprognostic (1.79e-1)" "validated prognostic unfavorable (9.00e-8)" "validated prognostic unfavorable (6.67e-4)" "unprognostic (1.42e-1)" "unprognostic (1.02e-2)" "unprognostic (1.81e-1)" "unprognostic (3.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.85e-3)" "unprognostic (6.27e-3)" "unprognostic (1.23e-1)" "unprognostic (1.36e-1)" "unprognostic (6.21e-3)" "unprognostic (3.36e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (4.59e-2)" "unprognostic (1.37e-2)" "unprognostic (2.84e-2)" GDPD3 MGC4171 ENSG00000102886 "Glycerophosphodiester phosphodiesterase domain containing 3" Q7L5L3 16 30104810-30113537 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 66.4" "Group enriched" "Detected in many" 6 "Esophageal apical cells: 799.7;Late spermatids: 706.0" "Group enriched" "Detected in many" 6 "Apical squamous epithelial cells: 799.7;Spermatogenic cell types: 706.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 63.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 2.5" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.5" "Cancer enhanced" "Detected in many" "breast cancer: 20.8" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Large ducts: 7201123.5;Proximal tubules: 3110933.5" "Tissue enhanced" "Detected in all" "lung: 629714.2;skeletal muscle: 963219.3" "HPA041148, HPA041470" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041148: , HPA041470: " "unprognostic (8.18e-2)" "unprognostic (7.17e-2)" "unprognostic (3.61e-1)" "unprognostic (8.67e-2)" "unprognostic (2.03e-1)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.65e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-1)" "unprognostic (1.52e-2)" "unprognostic (2.00e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (3.21e-3)" "unprognostic (3.16e-2)" "unprognostic (1.62e-1)" "unprognostic (4.43e-2)" "unprognostic (2.58e-1)" "unprognostic (1.28e-2)" "unprognostic (3.37e-2)" "unprognostic (1.91e-2)" "unprognostic (4.05e-2)" "unprognostic (3.24e-1)" "unprognostic (4.75e-2)" "unprognostic (2.43e-1)" "unprognostic (7.29e-2)" "unprognostic (1.97e-1)" "unprognostic (4.87e-1)" "unprognostic (1.84e-1)" "unprognostic (1.06e-1)" GDPD5 "GDE2, PP1665" ENSG00000158555 "Glycerophosphodiester phosphodiesterase domain containing 5" Q8WTR4 11 75434640-75525941 "Enzymes, Predicted membrane proteins" "Lipid metabolism, Neurogenesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.9;retina: 77.5" "Cell type enhanced" "Detected in many" "Adipocytes: 100.9;Cone photoreceptor cells: 231.9;Early spermatids: 68.8;Late spermatids: 309.2;Pituitary stem cells: 76.2;Retinal bipolar cells: 91.2;Rod photoreceptor cells: 160.1;Syncytiotrophoblasts: 134.6;Tuft cells: 103.8" "Cell type enhanced" "Detected in many" "Neuronal cells: 231.9;Spermatogenic cell types: 309.2;Trophoblast cells: 134.6" "Cell type enhanced" "Detected in many" "fibroblast: 44.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.7" "Group enriched" "Detected in many" 6 "granulocytes: 7.7;T-cells: 2.0" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 689386.1;Microglia and Neuropil: 231111.2" "Group enriched" "Detected in some" "cerebral cortex: 2926477.4;lymphoid tissue: 4222507.3" "HPA065257, HPA066762, HPA069281" Uncertain Approved "Golgi apparatus" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 3 "Golgi apparatus" "HPA065257: , HPA066762: , HPA069281: " "unprognostic (1.07e-1)" "unprognostic (5.42e-2)" "potential prognostic favorable (1.14e-4)" "unprognostic (7.41e-2)" "unprognostic (2.02e-1)" "unprognostic (1.50e-2)" "unprognostic (2.15e-1)" "unprognostic (4.77e-3)" "unprognostic (9.94e-3)" "unprognostic (3.89e-2)" "unprognostic (1.79e-3)" "unprognostic (9.74e-2)" "unprognostic (1.65e-3)" "unprognostic (1.58e-3)" "unprognostic (6.23e-2)" "unprognostic (4.28e-2)" "unprognostic (1.69e-1)" "unprognostic (2.30e-2)" "unprognostic (2.41e-1)" "unprognostic (2.62e-1)" "unprognostic (3.57e-1)" "unprognostic (2.09e-2)" "unprognostic (2.84e-2)" "unprognostic (1.79e-1)" "unprognostic (7.46e-2)" "unprognostic (5.70e-3)" "unprognostic (1.63e-1)" "unprognostic (8.46e-2)" "unprognostic (6.71e-2)" "potential prognostic unfavorable (6.00e-4)" "unprognostic (7.30e-2)" GET3 "ARSA-I, ASNA1, TRC40" ENSG00000198356 "Guided entry of tail-anchored proteins factor 3, ATPase" O43681 19 12737139-12748323 "Essential proteins, Predicted intracellular proteins, Transporters" Transport Hydrolase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 196.3;Esophageal suprabasal cells: 190.5;Late spermatids: 293.0;Oocytes: 193.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 293.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 123013676.4" "Low tissue specificity" "Detected in all" "HPA045951, HPA048087" Approved Enhanced Nucleoplasm,Nucleoli NA NA 20000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 56 Nucleoli Nucleoplasm "HPA045951: , HPA048087: " "unprognostic (8.32e-2)" "unprognostic (6.88e-2)" "unprognostic (4.14e-2)" "unprognostic (2.31e-1)" "unprognostic (1.34e-1)" "unprognostic (7.82e-2)" "unprognostic (2.09e-1)" "unprognostic (1.18e-1)" "unprognostic (2.50e-3)" "potential prognostic favorable (2.37e-8)" "unprognostic (1.97e-1)" "unprognostic (8.95e-3)" "unprognostic (2.86e-3)" "unprognostic (2.35e-1)" "unprognostic (7.53e-2)" "unprognostic (2.04e-3)" "unprognostic (3.35e-1)" "unprognostic (4.39e-3)" "unprognostic (3.10e-2)" "unprognostic (2.88e-1)" "unprognostic (4.72e-1)" "unprognostic (3.24e-2)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "unprognostic (2.46e-1)" "unprognostic (1.55e-1)" "unprognostic (5.44e-2)" "unprognostic (4.53e-2)" "unprognostic (9.16e-2)" GET4 "C7orf20, CEE, CGI-20, H_NH1244M04.5, TRC35" ENSG00000239857 "Guided entry of tail-anchored proteins factor 4" Q7L5D6 7 876554-896436 "Predicted intracellular proteins" Transport "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Astrocytes: 25.0;Bergmann glia: 19.4;Brain excitatory neurons: 14.6;Brain inhibitory neurons: 13.5;Choroid plexus epithelial cells: 11.2;Ependymal cells: 14.5;Microglia: 16.1;Oligodendrocyte progenitor cells: 13.4;Oligodendrocytes: 27.1;Other brain neurons: 18.2" "Group enriched" "Detected in some" 7 "Ciliated cells: 14.5;Glial cells: 27.1;Neuronal cells: 18.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 5943563.8" "Tissue enhanced" "Detected in many" "Stomach: 7330535.8" HPA019765 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Cytosol" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 67: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 48 "Nucleoli, Cytosol" "Nucleoplasm, Mitotic chromosome" "HPA019765: " "unprognostic (2.10e-1)" "unprognostic (2.96e-2)" "unprognostic (1.03e-1)" "unprognostic (5.59e-2)" "unprognostic (3.51e-3)" "unprognostic (1.54e-1)" "unprognostic (1.30e-2)" "unprognostic (2.13e-1)" "unprognostic (3.22e-3)" "unprognostic (1.59e-2)" "unprognostic (5.38e-2)" "unprognostic (3.63e-1)" "unprognostic (9.09e-2)" "unprognostic (1.94e-2)" "unprognostic (3.66e-3)" "unprognostic (7.42e-2)" "unprognostic (2.38e-2)" "unprognostic (7.21e-2)" "unprognostic (3.44e-1)" "unprognostic (8.27e-2)" "unprognostic (2.05e-1)" "unprognostic (3.38e-2)" "unprognostic (2.62e-3)" "unprognostic (1.04e-1)" "unprognostic (8.96e-2)" "unprognostic (3.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (8.35e-4)" "unprognostic (1.31e-2)" GFAP FLJ45472 ENSG00000131095 "Glial fibrillary acidic protein" P14136 17 44903159-44916937 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 15929.3" "Cell type enriched" "Detected in some" 4 "Astrocytes: 781.6" "Cell type enriched" "Detected in some" 4 "Glial cells: 781.6" "Cell type enriched" "Detected in many" 5 "astrocyte: 1723.3" "Cancer enriched" "Detected in many" 369 "Glioblastoma Multiforme (TCGA): 6588.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.1" "Group enriched" "Detected in many" 5 "granulocytes: 6.1;NK-cells: 1.7" "Cancer enriched" "Detected in many" 46 "Brain cancer: 164.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Astrocytes and Neuropil: 6234283865.4" "Tissue enriched" "Detected in many" "cerebral cortex: 3376081420.8" "CAB000039, HPA056030, HPA063513" Enhanced Supported Supported "Intermediate filaments" No No 67000000 "Cluster 20: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 28: Astrocytes - Homeostasis & neuron support" 175 "Intermediate filaments" "CAB000039: , HPA056030: , HPA063513: " "unprognostic (2.28e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.32e-2)" "unprognostic (1.84e-3)" "unprognostic (3.12e-1)" "unprognostic (3.20e-1)" "unprognostic (1.67e-2)" "unprognostic (1.14e-2)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (9.72e-5)" "unprognostic (5.09e-1)" "unprognostic (6.66e-2)" "unprognostic (2.69e-1)" "unprognostic (1.46e-2)" "unprognostic (2.59e-3)" "unprognostic (1.03e-2)" "unprognostic (1.85e-1)" "unprognostic (9.44e-2)" "unprognostic (5.83e-3)" "unprognostic (2.62e-2)" "unprognostic (1.56e-1)" "unprognostic (1.37e-2)" "unprognostic (7.95e-3)" "unprognostic (3.59e-1)" "unprognostic (3.22e-1)" "unprognostic (7.73e-2)" GFI1B ZNF163B ENSG00000165702 "Growth factor independent 1B transcriptional repressor" Q5VTD9 9 132944000-132991687 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "bone marrow: 36.8" "Cell type enhanced" "Detected in some" "Early spermatids: 190.6;Erythrocyte progenitors: 140.5;Late spermatids: 83.8;Megakaryocyte progenitors: 81.1;Megakaryocytes: 327.6;Platelets: 456.8;Tuft cells: 46.1" "Group enriched" "Detected in many" 6 "Erythrocytes: 140.5;Megakaryocytes: 327.6;Platelets: 456.8;Spermatogenic cell types: 190.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 19 "basophil: 195.8;eosinophil: 396.6" "Lineage enriched" "Detected in many" 26 "granulocytes: 396.6" "Cancer enriched" "Detected in some" 25 "Leukemia: 46.9" "Liver - Erythroid cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2893 "bone marrow: 289341.1" "CAB004420, HPA006291" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 27 "Nucleoplasm, Plasma membrane" "CAB004420: , HPA006291: " GFM2 "EF-G2mt, EFG2, FLJ21661" ENSG00000164347 "GTP dependent ribosome recycling factor mitochondrial 2" Q969S9 5 74721206-74767147 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in many" "intestine: 29804235.1" "HPA036863, HPA069871" Uncertain Approved "Nucleoplasm,Midbody ring,Mitochondria" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 Mitochondria "Nucleoplasm, Midbody ring" "HPA036863: , HPA069871: " "unprognostic (9.46e-2)" "unprognostic (3.15e-2)" "unprognostic (9.36e-2)" "unprognostic (1.80e-1)" "unprognostic (2.77e-1)" "unprognostic (3.29e-1)" "unprognostic (8.10e-2)" "unprognostic (1.98e-2)" "unprognostic (1.34e-2)" "unprognostic (2.32e-3)" "potential prognostic favorable (2.22e-7)" "unprognostic (6.77e-2)" "unprognostic (4.03e-2)" "unprognostic (4.13e-1)" "unprognostic (3.96e-1)" "unprognostic (3.42e-2)" "unprognostic (1.43e-2)" "unprognostic (7.84e-2)" "unprognostic (7.53e-2)" "unprognostic (8.73e-2)" "unprognostic (8.88e-3)" "unprognostic (8.75e-2)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (5.72e-2)" "unprognostic (1.42e-2)" "unprognostic (2.39e-1)" "unprognostic (3.75e-1)" "unprognostic (4.67e-2)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 196.2;Corticotrophs: 163.6;Neutrophil progenitors: 186.0;NK-cells: 298.2;Vascular endothelial cells: 220.2" "Cell type enhanced" "Detected in many" "NK-cells: 298.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Endothelial cells, Breast - Adipocytes (Breast), Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 21062904.8;Large ducts: 11384192.5;Microglia and Neuropil: 26357059.7;Neurons: 43102816.6;Pancreatic islets: 14541565.8" "Group enriched" "Detected in some" "bone marrow: 5789706.9;cerebral cortex: 3805751.9" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" "No annotated function" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 22 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: " "unprognostic (2.58e-1)" "unprognostic (3.29e-2)" "unprognostic (2.62e-3)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (5.79e-2)" "unprognostic (3.77e-2)" "unprognostic (3.18e-2)" "unprognostic (5.50e-3)" "validated prognostic favorable (1.91e-7)" "validated prognostic favorable (2.48e-4)" "unprognostic (6.43e-3)" "unprognostic (2.04e-2)" "unprognostic (6.03e-2)" "unprognostic (5.52e-2)" "unprognostic (3.32e-1)" "unprognostic (1.48e-1)" "unprognostic (1.33e-1)" "unprognostic (8.40e-3)" "unprognostic (1.50e-2)" "unprognostic (1.64e-1)" "unprognostic (6.04e-2)" "unprognostic (8.72e-2)" "unprognostic (3.91e-3)" "unprognostic (8.57e-2)" "unprognostic (3.38e-2)" "unprognostic (1.65e-2)" "unprognostic (2.43e-1)" "unprognostic (1.43e-2)" GFPT1 "GFA, GFAT, GFAT1, GFPT" ENSG00000198380 "Glutamine--fructose-6-phosphate transaminase 1" Q06210 2 69319780-69387250 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms" "Aminotransferase, Transferase" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Goblet cells: 461.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 248983423.3" "Tissue enhanced" "Detected in all" "intestine: 149175280.2;pancreas: 167639165.6" HPA047240 Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 67000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 17: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 13: Non-specific - Mixed function" "Cluster 70: Intestinal goblet cells - Mucin production" 7 "Nucleoplasm, Nucleoli" "Nucleoli fibrillar center" "HPA047240: " "unprognostic (1.17e-2)" "unprognostic (1.08e-3)" "unprognostic (1.48e-1)" "unprognostic (3.77e-3)" "unprognostic (6.76e-3)" "unprognostic (9.24e-2)" "unprognostic (1.59e-1)" "unprognostic (3.61e-2)" "unprognostic (8.98e-2)" "unprognostic (9.19e-3)" "potential prognostic favorable (3.38e-6)" "unprognostic (2.13e-2)" "unprognostic (3.88e-3)" "unprognostic (2.96e-2)" "unprognostic (8.02e-2)" "unprognostic (5.45e-2)" "unprognostic (1.05e-1)" "unprognostic (1.55e-2)" "unprognostic (4.53e-2)" "unprognostic (5.53e-2)" "unprognostic (4.78e-3)" "unprognostic (8.94e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (1.63e-1)" "unprognostic (8.35e-2)" "unprognostic (4.76e-1)" "unprognostic (8.47e-2)" "unprognostic (7.68e-2)" GFUS "FX, P35B, SDR4E1, TSTA3" ENSG00000104522 "GDP-L-fucose synthase" Q13630 8 143612618-143618048 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 184.3;Gastric chief cells: 131.0;Late primary spermatocytes: 70.4;Late spermatids: 241.4;Suprabasal keratinocytes: 64.3" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 131.0;Secretory cells: 184.3;Spermatogenic cell types: 241.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA023361 Approved Approved Nucleoplasm,Cytosol Yes No 1100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 Cytosol Nucleoplasm "HPA023361: " "unprognostic (2.45e-1)" "unprognostic (2.66e-2)" "unprognostic (2.10e-2)" "unprognostic (1.15e-1)" "unprognostic (1.42e-2)" "unprognostic (2.26e-1)" "unprognostic (5.08e-2)" "unprognostic (2.46e-2)" "unprognostic (6.83e-2)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.25e-3)" "unprognostic (1.39e-1)" "unprognostic (7.14e-2)" "unprognostic (9.90e-2)" "unprognostic (5.31e-2)" "unprognostic (1.22e-2)" "unprognostic (4.67e-2)" "unprognostic (1.02e-2)" "unprognostic (3.32e-1)" "unprognostic (2.25e-3)" "unprognostic (5.24e-2)" "unprognostic (5.20e-1)" "unprognostic (4.14e-2)" "unprognostic (1.31e-3)" "unprognostic (1.06e-1)" "unprognostic (3.51e-2)" "unprognostic (1.59e-1)" "unprognostic (1.43e-1)" "unprognostic (1.25e-1)" GGPS1 GGPPS1 ENSG00000152904 "Geranylgeranyl diphosphate synthase 1" O95749 1 235327350-235344532 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isoprene biosynthesis, Lipid metabolism" Transferase "Congenital muscular dystrophy, Deafness, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 197.6;Early spermatids: 117.6;Epicardial cells: 332.0;Late primary spermatocytes: 101.7;Late spermatids: 884.2" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 332.0;Myocytes: 197.6;Spermatogenic cell types: 884.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 4037374.6" "Low tissue specificity" "Detected in all" "HPA029472, HPA050727" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 10 Cytosol Nucleoplasm "HPA029472: , HPA050727: " "unprognostic (1.66e-1)" "unprognostic (2.28e-2)" "unprognostic (1.07e-1)" "unprognostic (3.78e-2)" "unprognostic (2.26e-1)" "unprognostic (9.98e-2)" "unprognostic (2.80e-1)" "unprognostic (1.69e-1)" "unprognostic (1.50e-2)" "unprognostic (5.91e-3)" "potential prognostic favorable (1.08e-4)" "unprognostic (1.83e-1)" "unprognostic (2.72e-1)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (9.58e-3)" "unprognostic (5.97e-2)" "unprognostic (3.17e-2)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" "unprognostic (9.75e-2)" "unprognostic (2.89e-2)" "unprognostic (2.68e-1)" "unprognostic (3.55e-2)" "unprognostic (1.25e-2)" "unprognostic (3.30e-2)" "unprognostic (2.88e-3)" "unprognostic (3.02e-2)" "unprognostic (2.59e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" GGT1 "CD224, D22S672, D22S732, GGT" ENSG00000100031 "Gamma-glutamyltransferase 1" P19440 22 24594811-24629005 "Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis, Lipid metabolism" "Acyltransferase, Hydrolase, Protease, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 149.7;liver: 103.5" "Cell type enhanced" "Detected in some" "Colonocytes: 22.4;Distal convoluted tubule cells: 11.5;Enterocytes: 49.3;Epididymal principal cells: 30.3;Gastric chief cells: 15.3;Loop of henle epithelial cells: 16.0;Proximal tubule cells: 128.8" "Cell type enhanced" "Detected in many" "Enterocytes: 49.3;Renal nephron cells: 128.8;Reproductive supporting cells: 30.3" "Group enriched" "Detected in some" 5 "fibroblast: 2.3;pericyte: 5.9" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 231.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 119.6" "Adrenal gland - Fibroblasts, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Proximal tubules: 47899136.3" "Group enriched" "Detected in some" "intestine: 30294987.0;kidney: 68827912.5" "HPA045635, HPA047534, HPA065444" Supported Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA 3400000 "Cluster 28: Neutrophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 4 Vesicles "HPA045635: , HPA047534: , HPA065444: " "potential prognostic unfavorable (6.50e-8)" "unprognostic (1.36e-3)" "unprognostic (6.84e-3)" "unprognostic (7.62e-2)" "unprognostic (8.29e-2)" "unprognostic (7.51e-3)" "unprognostic (6.17e-3)" "potential prognostic favorable (9.95e-4)" "unprognostic (2.28e-3)" "unprognostic (4.79e-1)" "potential prognostic favorable (1.44e-4)" "unprognostic (1.72e-1)" "unprognostic (1.88e-3)" "unprognostic (5.57e-3)" "unprognostic (9.20e-3)" "unprognostic (5.97e-3)" "unprognostic (1.01e-1)" "unprognostic (3.60e-2)" "unprognostic (1.59e-2)" "unprognostic (1.96e-2)" "unprognostic (1.09e-1)" "unprognostic (5.16e-2)" "unprognostic (1.09e-1)" "unprognostic (9.37e-2)" "unprognostic (2.60e-1)" "unprognostic (3.01e-1)" "unprognostic (1.02e-2)" "unprognostic (1.06e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (3.13e-1)" GGT7 "D20S101, dJ18C9.2, GGTL3, GGTL5" ENSG00000131067 "Gamma-glutamyltransferase 7" Q9UJ14 20 34844720-34872856 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glutathione biosynthesis" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 158.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 7569990.6;Pancreatic islets: 8806149.0" "Group enriched" "Detected in many" "cerebral cortex: 15775674.9;pancreas: 4060159.7" "HPA013204, HPA013339" Approved Approved Nucleoplasm,Vesicles NA NA 650000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 Vesicles Nucleoplasm "HPA013204: , HPA013339: " "unprognostic (1.06e-1)" "unprognostic (9.81e-3)" "unprognostic (3.65e-1)" "unprognostic (6.69e-2)" "unprognostic (7.59e-2)" "unprognostic (1.05e-2)" "unprognostic (9.94e-2)" "unprognostic (1.45e-2)" "unprognostic (3.32e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (4.07e-2)" "unprognostic (1.00e-2)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (4.85e-2)" "unprognostic (6.15e-2)" "unprognostic (2.21e-1)" "unprognostic (4.61e-1)" "unprognostic (8.19e-3)" "unprognostic (3.78e-2)" "unprognostic (1.76e-1)" "unprognostic (1.79e-3)" "unprognostic (9.07e-3)" "unprognostic (5.38e-2)" "unprognostic (1.10e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-2)" "unprognostic (9.24e-2)" "unprognostic (3.52e-2)" "unprognostic (7.60e-2)" "unprognostic (3.70e-2)" GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 79.5;liver: 199.5" "Group enriched" "Detected in many" 4 "Adipocytes: 3141.2;Myonuclei: 1159.6" "Group enriched" "Detected in many" 4 "Adipocytes: 3141.2;Myocytes: 1159.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 17.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 6.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 3165 "liver: 316485.7" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" Receptor NA NA 2200000 3600000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 3: Rhabdoid - Membrane components" "Cluster 89: Adipocytes - Lipid metabolism" 31 "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: , HPA057705: " "unprognostic (6.47e-2)" "unprognostic (1.26e-2)" "unprognostic (8.47e-2)" "unprognostic (1.11e-2)" "unprognostic (3.23e-1)" "unprognostic (4.88e-2)" "unprognostic (2.95e-1)" "potential prognostic favorable (4.80e-5)" "unprognostic (3.73e-2)" "unprognostic (6.78e-2)" "validated prognostic favorable (2.53e-10)" "validated prognostic favorable (1.24e-4)" "unprognostic (2.09e-1)" "validated prognostic favorable (3.06e-6)" "validated prognostic favorable (1.71e-4)" "unprognostic (2.92e-2)" "unprognostic (1.51e-1)" "unprognostic (8.98e-2)" "unprognostic (5.90e-2)" "unprognostic (2.97e-3)" "unprognostic (3.57e-2)" "unprognostic (8.96e-2)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (5.69e-3)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (6.29e-4)" GIGYF1 "GYF1, PERQ1" ENSG00000146830 "GRB10 interacting GYF protein 1" O75420 7 100679507-100694250 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 3749466.7" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19579713.5" "HPA020999, HPA023995" Enhanced Approved "Vesicles,Microtubules,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 68 Vesicles "Microtubules, Mitotic spindle, Primary cilium, Basal body" "HPA020999: , HPA023995: " "unprognostic (4.28e-3)" "unprognostic (3.73e-3)" "unprognostic (7.00e-2)" "unprognostic (2.92e-2)" "unprognostic (1.92e-2)" "unprognostic (7.25e-2)" "unprognostic (2.59e-1)" "unprognostic (1.92e-2)" "unprognostic (1.15e-3)" "unprognostic (8.18e-2)" "unprognostic (2.68e-2)" "unprognostic (1.37e-2)" "unprognostic (8.12e-3)" "unprognostic (1.39e-3)" "unprognostic (1.82e-1)" "unprognostic (1.79e-2)" "unprognostic (1.89e-1)" "unprognostic (3.14e-2)" "unprognostic (2.59e-2)" "unprognostic (3.03e-3)" "unprognostic (4.15e-2)" "potential prognostic favorable (1.77e-5)" "potential prognostic unfavorable (9.45e-4)" "unprognostic (8.10e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-2)" "unprognostic (2.25e-2)" "unprognostic (8.45e-2)" "unprognostic (3.22e-1)" "unprognostic (2.18e-2)" "unprognostic (1.87e-1)" GINS2 "Pfs2, PSF2" ENSG00000131153 "GINS complex subunit 2" Q9Y248 16 85676198-85690073 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 118.0;Early primary spermatocytes: 246.7;Enteric stem cells: 55.3;Erythrocyte progenitors: 72.9;Esophageal basal cells: 66.1;Migrating cytotrophoblasts: 60.6;Oocytes: 423.7;Syncytiotrophoblasts: 71.6" "Group enriched" "Detected in many" 4 "Oocytes: 423.7;Spermatogenic cell types: 246.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1028 "Granulosa cells: 102777.8" "Tissue enriched" "Detected in some" "bone marrow: 9497523.9" HPA057285 Uncertain Approved Nucleoplasm No Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 41: Oocytes - Oogenesis" 25 Nucleoplasm "HPA057285: " "unprognostic (1.16e-1)" "unprognostic (4.50e-2)" "unprognostic (7.96e-2)" "unprognostic (6.05e-3)" "unprognostic (1.93e-1)" "unprognostic (3.30e-1)" "unprognostic (2.03e-1)" "unprognostic (5.56e-2)" "unprognostic (6.11e-2)" "unprognostic (1.38e-1)" "unprognostic (1.86e-2)" "unprognostic (4.61e-3)" "unprognostic (2.66e-2)" "validated prognostic unfavorable (7.63e-4)" "validated prognostic unfavorable (1.09e-6)" "validated prognostic unfavorable (8.97e-4)" "validated prognostic unfavorable (2.60e-4)" "unprognostic (3.68e-2)" "unprognostic (4.27e-2)" "unprognostic (9.81e-2)" "unprognostic (1.51e-1)" "unprognostic (1.84e-2)" "unprognostic (3.04e-3)" "unprognostic (1.11e-2)" "unprognostic (1.06e-1)" "unprognostic (8.89e-2)" "unprognostic (1.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.31e-1)" "unprognostic (5.69e-3)" "unprognostic (9.85e-2)" GINS3 "FLJ13912, PSF3" ENSG00000181938 "GINS complex subunit 3" Q9BRX5 16 58295080-58406147 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 232.7;Cardiomyocytes: 65.7;Early spermatids: 117.5;Ependymal cells: 68.8;Late primary spermatocytes: 99.8;Oligodendrocyte progenitor cells: 75.8;Oligodendrocytes: 40.6;Schwann cells: 84.5" "Group enriched" "Detected in many" 4 "Ciliated cells: 68.8;Glial cells: 232.7;Myocytes: 65.7;Spermatogenic cell types: 117.5" "Cell type enhanced" "Detected in all" "astrocyte: 307.9;committed oligodendrocyte precursor: 207.2;oligodendrocyte precursor cell: 111.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Colon - Enteric glia cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 3265907.2" "Tissue enriched" "Detected in some" "bone marrow: 6427831.6" "HPA041216, HPA048209" Uncertain Enhanced Nucleoplasm No No "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 54: Immune cells - T cell receptor" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 28: Astrocytes - Homeostasis & neuron support" 25 Nucleoplasm "HPA041216: , HPA048209: " "unprognostic (3.73e-2)" "unprognostic (2.32e-1)" "unprognostic (2.53e-1)" "unprognostic (1.97e-1)" "unprognostic (6.17e-2)" "unprognostic (3.62e-2)" "unprognostic (2.07e-1)" "unprognostic (1.63e-3)" "unprognostic (2.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.61e-3)" "unprognostic (6.41e-2)" "unprognostic (1.25e-1)" "validated prognostic unfavorable (1.75e-4)" "validated prognostic unfavorable (2.68e-4)" "unprognostic (6.15e-3)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (3.08e-2)" "unprognostic (2.33e-2)" "unprognostic (2.21e-1)" "unprognostic (3.99e-1)" "unprognostic (2.48e-3)" "unprognostic (6.99e-2)" "unprognostic (2.73e-2)" "unprognostic (3.54e-2)" "unprognostic (1.36e-1)" "unprognostic (2.58e-3)" "unprognostic (2.23e-2)" "unprognostic (6.39e-2)" "unprognostic (4.19e-1)" "unprognostic (1.68e-1)" GIT1 ENSG00000108262 "GIT ArfGAP 1" Q9Y2X7 17 29573475-29594054 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 127.9" "Cell type enhanced" "Detected in many" "Early spermatids: 98.2;Late primary spermatocytes: 99.3;Late spermatids: 134.2" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 134.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 23218512.6;Microglia and Neuropil: 27313031.3" "Tissue enriched" "Detected in many" "cerebral cortex: 56525682.9" "HPA004059, HPA004186" Enhanced Supported "Focal adhesion sites,Mitochondria,Cytosol" NA NA 27000 "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 80 "Focal adhesion sites, Cytosol" Mitochondria "HPA004059: , HPA004186: " "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (1.59e-1)" "unprognostic (2.86e-1)" "unprognostic (3.40e-2)" "unprognostic (1.68e-1)" "unprognostic (2.22e-1)" "unprognostic (3.95e-3)" "unprognostic (6.27e-2)" "unprognostic (4.66e-2)" "potential prognostic favorable (2.04e-5)" "unprognostic (1.48e-2)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (7.26e-5)" "unprognostic (4.97e-3)" "unprognostic (5.90e-3)" "unprognostic (5.40e-2)" "unprognostic (2.51e-1)" "unprognostic (1.67e-3)" "unprognostic (2.71e-2)" "unprognostic (1.36e-1)" "unprognostic (2.97e-2)" "unprognostic (1.67e-2)" "unprognostic (8.80e-2)" "unprognostic (4.20e-3)" "unprognostic (3.30e-3)" "unprognostic (3.34e-1)" "unprognostic (4.33e-2)" "unprognostic (2.26e-1)" "unprognostic (1.93e-2)" "unprognostic (4.48e-2)" GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "brain: 67.0" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 58.3;Oligodendrocytes: 41.1" "Group enriched" "Detected in many" 4 "Endothelial cells: 58.3;Glial cells: 41.1" "Group enriched" "Detected in many" 14 "committed oligodendrocyte precursor: 19.0;oligodendrocyte: 61.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 36 "cerebral cortex: 3619.7" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (1.77e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" "unprognostic (3.20e-3)" "unprognostic (1.63e-1)" "unprognostic (7.88e-2)" "unprognostic (2.78e-1)" "unprognostic (1.11e-3)" "unprognostic (1.75e-1)" "unprognostic (1.46e-1)" "unprognostic (1.57e-1)" "unprognostic (1.53e-1)" "unprognostic (3.81e-2)" "unprognostic (6.68e-2)" "unprognostic (9.89e-2)" "unprognostic (2.26e-2)" "unprognostic (2.79e-2)" "unprognostic (1.52e-1)" "unprognostic (2.33e-1)" "unprognostic (9.17e-2)" "unprognostic (5.56e-2)" "unprognostic (8.03e-2)" "unprognostic (2.51e-1)" "unprognostic (3.13e-2)" GLCCI1 "FAM117C, GIG18, TSSN1" ENSG00000106415 "Glucocorticoid induced 1" Q86VQ1 7 7968796-8094272 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 31.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 457.4;Oligodendrocyte progenitor cells: 387.5;Plasma cells: 789.3;Renal collecting duct intercalated cells: 468.7" "Cell type enhanced" "Detected in all" "Plasma cells: 789.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Myeloma: 49.0" "Minor Salivary Gland - Plasma cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 3039127.7;Oocytes: 2067023.3" "Tissue enhanced" "Detected in many" "ovary: 1580857.1" "HPA001674, HPA005987" Approved Approved Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 10 Nucleoli "HPA001674: , HPA005987: " "unprognostic (3.28e-2)" "unprognostic (1.91e-2)" "unprognostic (6.69e-2)" "unprognostic (1.11e-1)" "unprognostic (6.62e-2)" "unprognostic (1.22e-1)" "unprognostic (4.43e-2)" "unprognostic (1.06e-3)" "unprognostic (3.81e-3)" "unprognostic (1.29e-2)" "potential prognostic favorable (1.11e-5)" "unprognostic (1.76e-1)" "unprognostic (2.73e-1)" "unprognostic (1.39e-1)" "unprognostic (5.83e-2)" "unprognostic (7.53e-3)" "unprognostic (2.92e-1)" "unprognostic (9.86e-2)" "unprognostic (9.06e-2)" "unprognostic (1.00e-1)" "unprognostic (4.67e-2)" "unprognostic (6.53e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-1)" "unprognostic (2.46e-2)" "unprognostic (1.37e-2)" "unprognostic (2.09e-1)" "unprognostic (2.43e-1)" "unprognostic (1.18e-1)" "unprognostic (2.02e-1)" "unprognostic (3.73e-2)" GLI2 "HPE9, THP1, THP2" ENSG00000074047 "GLI family zinc finger 2" P10070 2 120735623-120992653 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 9.8" "Cell type enhanced" "Detected in many" "Astrocytes: 83.3;Bergmann glia: 188.4;Early spermatids: 58.9;Ependymal cells: 60.1;Epicardial cells: 79.6;Fibro-adipogenic progenitors: 96.8;Hepatic stellate cells: 64.5;Lactotrophs: 87.1;Late spermatids: 84.2;Leydig cells: 103.1;Mesothelial cells: 63.1;Myosatellite cells: 114.9;Ovarian stromal cells: 70.4;Peritubular myoid cells: 118.0;Somatotrophs: 201.9;Thyrotrophs: 83.1" "Cell type enhanced" "Detected in many" "Glial cells: 188.4;Pituitary endocrine cells: 201.9;Stem cells: 114.9;Stromal cells: 118.0" "Group enriched" "Detected in many" 4 "astrocyte: 104.4;Bergmann glia: 181.7;ependymal cell: 65.9;fibroblast: 57.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 8.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 66 "Proximal tubules: 6626.3" "Not detected" "Not detected" "CAB008558, HPA074275" Approved Supported "Nucleoplasm,Nucleoli,Centrosome,Basal body" No No "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 94: Gonadal somatic cells - Mixed function" 10 Nucleoli "Nucleoplasm, Centrosome, Basal body" "CAB008558: , HPA074275: " "unprognostic (2.99e-1)" "unprognostic (1.91e-2)" "unprognostic (3.71e-2)" "unprognostic (1.26e-1)" "unprognostic (4.55e-2)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (1.65e-5)" "unprognostic (2.25e-1)" "unprognostic (2.65e-1)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.80e-1)" "unprognostic (4.81e-3)" "unprognostic (6.97e-2)" "unprognostic (8.36e-2)" "unprognostic (9.82e-2)" "unprognostic (1.50e-1)" "unprognostic (2.19e-2)" GLI3 "ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV" ENSG00000106571 "GLI family zinc finger 3" P10071 7 41960949-42264100 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 474.3;Cytotrophoblasts: 176.6;Fibro-adipogenic progenitors: 436.1;Medullary thymic epithelial cells: 204.0;Mesothelial cells: 315.9;Pituicytes/FSCs: 273.6;Syncytiotrophoblasts: 332.2" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 315.9;Fibro-adipogenic progenitors: 436.1;Glial cells: 474.3;Trophoblast cells: 332.2" "Cell type enhanced" "Detected in many" "astrocyte: 487.7;ependymal cell: 145.9;fibroblast: 171.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 30 "kidney: 2950.0" HPA005534 Approved Approved Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 54: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 17 Nucleoplasm "Nucleoli, Vesicles" "HPA005534: " "unprognostic (1.93e-1)" "unprognostic (4.51e-2)" "unprognostic (4.63e-1)" "unprognostic (1.47e-2)" "unprognostic (3.50e-2)" "unprognostic (1.73e-1)" "unprognostic (3.37e-1)" "potential prognostic unfavorable (2.64e-4)" "unprognostic (4.82e-2)" "unprognostic (7.22e-2)" "unprognostic (1.77e-1)" "unprognostic (3.22e-1)" "unprognostic (6.78e-2)" "unprognostic (5.74e-2)" "unprognostic (1.64e-1)" "unprognostic (2.64e-1)" "unprognostic (8.13e-2)" "unprognostic (1.50e-2)" "unprognostic (2.63e-1)" "unprognostic (4.49e-2)" "unprognostic (1.15e-1)" "unprognostic (4.21e-2)" "unprognostic (2.81e-2)" "unprognostic (1.80e-1)" "unprognostic (1.11e-2)" "unprognostic (1.24e-1)" "unprognostic (1.89e-3)" "unprognostic (1.92e-1)" GLI4 "HKR4, ZNF928" ENSG00000250571 "GLI family zinc finger 4" P10075 8 143267433-143276931 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA023131 Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 3 "Nucleoplasm, Cytokinetic bridge" "HPA023131: " "unprognostic (5.70e-2)" "unprognostic (4.56e-2)" "unprognostic (2.39e-1)" "unprognostic (2.39e-2)" "unprognostic (1.33e-2)" "unprognostic (1.80e-1)" "unprognostic (1.13e-1)" "unprognostic (3.68e-2)" "unprognostic (5.20e-2)" "unprognostic (1.32e-2)" "unprognostic (1.43e-3)" "unprognostic (1.46e-1)" "unprognostic (4.20e-1)" "unprognostic (1.30e-2)" "unprognostic (2.26e-1)" "unprognostic (5.49e-2)" "unprognostic (3.01e-2)" "unprognostic (1.93e-1)" "unprognostic (2.44e-2)" "unprognostic (1.61e-1)" "unprognostic (9.78e-2)" "unprognostic (3.52e-2)" "unprognostic (2.18e-2)" "unprognostic (7.99e-2)" "unprognostic (3.30e-2)" "unprognostic (1.78e-1)" "unprognostic (3.08e-2)" "unprognostic (2.56e-1)" "unprognostic (2.45e-1)" "unprognostic (8.30e-3)" "unprognostic (1.59e-2)" GLIS2 NPHP7 ENSG00000126603 "GLIS family zinc finger 2" Q9BZE0 16 4314761-4339597 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Ciliopathy, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.0;Choroid plexus epithelial cells: 9.9;Distal convoluted tubule cells: 22.6;Loop of henle epithelial cells: 22.3;Oligodendrocyte progenitor cells: 7.2;Papillary tip epithelial cells: 12.0;Podocytes: 9.5;Proximal tubule cells: 35.6;Renal collecting duct intercalated cells: 19.3;Renal collecting duct principal cells: 28.4;Renal connecting tubule cells: 25.2" "Cell type enhanced" "Detected in some" "Ciliated cells: 9.9;Ductal cells: 28.4;Glial cells: 8.0;Renal nephron cells: 35.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 33.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA062755, HPA065406" Approved "Nucleoplasm,Basal body" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 88: Proximal tubular cells - Transmembrane transport" 32 Nucleoplasm "Basal body" "HPA062755: , HPA065406: " "unprognostic (3.69e-3)" "unprognostic (1.78e-1)" "unprognostic (1.99e-1)" "unprognostic (1.08e-2)" "unprognostic (5.48e-2)" "unprognostic (1.32e-1)" "unprognostic (4.76e-2)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (6.00e-3)" "potential prognostic favorable (5.58e-4)" "unprognostic (1.56e-1)" "unprognostic (4.29e-1)" "unprognostic (1.90e-2)" "unprognostic (4.31e-2)" "unprognostic (1.94e-1)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.29e-2)" "unprognostic (2.32e-1)" "unprognostic (1.13e-1)" "unprognostic (3.43e-1)" "unprognostic (1.19e-1)" "unprognostic (1.06e-1)" "unprognostic (5.83e-2)" "unprognostic (1.13e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-2)" "unprognostic (4.33e-3)" GLIS3 "MGC33662, ZNF515" ENSG00000107249 "GLIS family zinc finger 3" Q8NEA6 9 3824127-4348392 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Congenital hypothyroidism, Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 14.0" "Cell type enhanced" "Detected in many" "Astrocytes: 1075.2;Choroid plexus epithelial cells: 1624.0;Endometrial glandular cells: 920.2;Ependymal cells: 1552.5;Pancreatic duct cells: 1414.4;Pituicytes/FSCs: 856.8;Renal collecting duct intercalated cells: 860.4;Renal collecting duct principal cells: 1210.0;Renal connecting tubule cells: 1923.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 1624.0;Ductal cells: 1923.3" "Group enriched" "Detected in all" 5 "astrocyte: 1626.4;Bergmann glia: 824.6;choroid plexus epithelial cell: 1289.9;ependymal cell: 1730.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 296 "Fallopian tube cells: 29601.9" "Not detected" "Not detected" HPA056426 Approved Approved "Nucleoplasm,Golgi apparatus,Primary cilium" NA NA "Cluster 55: Breast - Lactation" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 5 Nucleoplasm "Golgi apparatus, Primary cilium" "HPA056426: " "unprognostic (2.45e-1)" "unprognostic (4.40e-2)" "unprognostic (4.99e-1)" "unprognostic (5.52e-2)" "unprognostic (3.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (5.03e-1)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "potential prognostic favorable (9.12e-5)" "unprognostic (2.53e-2)" "unprognostic (4.53e-2)" "unprognostic (9.40e-3)" "unprognostic (2.01e-2)" "unprognostic (5.18e-2)" "unprognostic (2.21e-3)" "unprognostic (5.02e-2)" "unprognostic (1.70e-1)" "unprognostic (2.15e-1)" "unprognostic (4.47e-2)" "unprognostic (2.73e-2)" "unprognostic (4.31e-2)" "unprognostic (2.78e-1)" "unprognostic (1.19e-2)" "unprognostic (4.02e-2)" "unprognostic (9.22e-3)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (9.69e-3)" GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703145 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 424.3" "Cell type enhanced" "Detected in all" "Trophoblast cells: 424.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 195831648.8" "Low tissue specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 2000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 49: HMC-1 - Innate immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 6 "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: " "unprognostic (1.94e-1)" "unprognostic (1.15e-2)" "unprognostic (1.59e-2)" "unprognostic (4.12e-1)" "unprognostic (8.69e-2)" "unprognostic (3.25e-1)" "unprognostic (3.57e-3)" "unprognostic (2.86e-1)" "unprognostic (5.56e-2)" "unprognostic (5.67e-3)" "validated prognostic favorable (1.37e-5)" "validated prognostic favorable (6.28e-4)" "unprognostic (3.19e-2)" "validated prognostic unfavorable (4.65e-4)" "validated prognostic unfavorable (2.84e-5)" "unprognostic (1.94e-1)" "unprognostic (1.15e-1)" "unprognostic (2.54e-2)" "unprognostic (1.29e-1)" "unprognostic (3.41e-3)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (4.38e-1)" "unprognostic (1.08e-1)" "unprognostic (6.00e-3)" "unprognostic (8.08e-2)" "unprognostic (1.06e-1)" "unprognostic (9.13e-3)" "unprognostic (2.10e-1)" "unprognostic (5.86e-2)" "unprognostic (1.29e-1)" GLOD4 "C17orf25, CGI-150, HC71" ENSG00000167699 "Glyoxalase domain containing 4" Q9HC38 17 757097-782294 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Parietal cells: 809.7" "Cell type enriched" "Detected in all" 6 "Gastric glandular cells: 809.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA021623, HPA023246, HPA023248" Enhanced Approved Cytosol NA NA 3500000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 2 Cytosol "HPA021623: , HPA023246: , HPA023248: " "unprognostic (1.28e-2)" "unprognostic (9.43e-2)" "unprognostic (1.99e-2)" "unprognostic (4.69e-2)" "unprognostic (3.49e-2)" "unprognostic (3.18e-1)" "unprognostic (2.49e-1)" "unprognostic (1.11e-2)" "unprognostic (2.53e-1)" "unprognostic (2.62e-1)" "validated prognostic favorable (8.19e-11)" "validated prognostic favorable (7.25e-4)" "potential prognostic favorable (2.78e-4)" "unprognostic (2.76e-1)" "unprognostic (1.69e-1)" "unprognostic (3.79e-2)" "unprognostic (4.43e-2)" "unprognostic (2.47e-1)" "unprognostic (1.48e-1)" "unprognostic (2.68e-1)" "unprognostic (4.20e-2)" "unprognostic (2.37e-1)" "unprognostic (3.51e-2)" "unprognostic (8.52e-2)" "unprognostic (2.26e-2)" "unprognostic (2.55e-1)" "unprognostic (1.98e-1)" "unprognostic (3.41e-3)" "unprognostic (2.60e-1)" "unprognostic (1.35e-1)" "unprognostic (1.75e-2)" GLP1R GLP-1R ENSG00000112164 "Glucagon like peptide 1 receptor" P43220 6 39048781-39091303 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 2.6;pancreas: 8.6" "Cell type enhanced" "Detected in some" "Lacrimal acinar cells: 19.0;Neuroendocrine cells: 8.0;Other brain neurons: 10.8;Pancreatic acinar cells: 15.5;Pancreatic islet cells: 23.3;Proximal tubule cells: 5.7;Salivary acinar cells: 4.8;Tuft cells: 46.1" "Cell type enhanced" "Detected in some" "Acinar cells: 19.0;Neuronal cells: 10.8;Pancreatic islet cells: 23.3;Secretory gland support: 46.1" "Cell type enhanced" "Detected in some" "splatter: 5.3;vascular associated smooth muscle cell: 3.0" "Cancer enhanced" "Detected in some" "Pancreatic Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Leukemia: 1.9" "Heart muscle - Cardiomyocytes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "basal ganglia: 20.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" CAB080541 Approved "Nuclear bodies,Golgi apparatus,Plasma membrane,Centrosome" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 52 "Nuclear bodies, Plasma membrane" "Golgi apparatus, Centrosome" "CAB080541: " "unprognostic (7.38e-2)" "unprognostic (3.11e-1)" "unprognostic (2.28e-2)" GLRA1 STHE ENSG00000145888 "Glycine receptor alpha 1" P23415 5 151822513-151924851 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "retina: 2.3" "Cell type enhanced" "Detected in many" "Adipocytes: 19.4;Adrenal medulla cells: 42.5;Cardiomyocytes: 39.9;Epicardial cells: 15.9;Hepatic stellate cells: 25.8;Myonuclei: 21.4;Other brain neurons: 18.5;Retinal amacrine cells: 30.5;Retinal bipolar cells: 81.9;Retinal ganglion cells: 23.2;Rod photoreceptor cells: 16.7" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 42.5;Myocytes: 39.9;Neuronal cells: 81.9" "Cell type enhanced" "Detected in many" "lower rhombic lip: 33.0;splatter: 41.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Pancreas - Beta cells" "Group enriched" "Detected in many" 5 "hypothalamus: 9.4;midbrain: 15.1;pons and medulla: 26.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA078885, CAB079042" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 43: Hindbrain - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Vesicles, Plasma membrane" "CAB079042: , HPA078885: " "unprognostic (4.02e-2)" GLRA2 GLR ENSG00000101958 "Glycine receptor alpha 2" P23416 X 14529298-14731812 "Disease related genes, FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.9;intestine: 1.5;retina: 3.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 60.2;Brain inhibitory neurons: 58.2;Colonocytes: 42.6;Epicardial cells: 22.7;Gonadotrophs: 24.2;Oligodendrocytes: 21.1;Other brain neurons: 61.7;Retinal amacrine cells: 176.8;Retinal ganglion cells: 69.5;Retinal horizontal cells: 66.1" "Cell type enriched" "Detected in many" 4 "Neuronal cells: 176.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Rectum Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Gonadotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB070422, HPA078885" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 40: Non-specific - Unknown function" "Cluster 109: Neurons - Neuronal signaling" "Vesicles, Plasma membrane" "CAB070422: , HPA078885: " "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" "unprognostic (2.88e-2)" "unprognostic (1.20e-1)" "unprognostic (2.49e-1)" "unprognostic (9.84e-2)" GLRA3 ENSG00000145451 "Glycine receptor alpha 3" O75311 4 174636920-174829247 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 5.2;breast: 1.9" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 59.5;Brain inhibitory neurons: 33.8;Breast hormone-responsive cells: 55.4;Early spermatids: 42.0;Gonadotrophs: 63.0;Late spermatids: 30.7;Other brain neurons: 72.9;Pancreatic islet cells: 26.8;Retinal amacrine cells: 116.2;Somatotrophs: 18.5;Thyrotrophs: 31.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 31.9;Luminal cells: 55.4;Neuronal cells: 116.2;Pituitary endocrine cells: 63.0;Spermatogenic cell types: 42.0" "Cell type enhanced" "Detected in many" "amygdala excitatory: 161.0;upper-layer intratelencephalic: 145.1" "Cancer enriched" "Detected in single" 4 "Breast Invasive Carcinoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lymphoma: 1.4" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Beta cells, Pituitary gland - Thyrotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 30 "cerebral cortex: 2968.0" HPA078885 Approved "Vesicles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 109: Neurons - Neuronal signaling" 1 "Vesicles, Plasma membrane" "HPA078885: " "unprognostic (1.57e-2)" "unprognostic (2.44e-1)" "unprognostic (4.32e-3)" "unprognostic (1.36e-1)" GLS "GAC, GAM, GLS1, KGA, KIAA0838" ENSG00000115419 Glutaminase O94925 2 190880821-190965552 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cataract, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 144.3" "Cell type enhanced" "Detected in many" "Podocytes: 820.8;Renal collecting duct principal cells: 812.4;Renal connecting tubule cells: 846.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney cancer: 363.0" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 254760747.8" "Tissue enriched" "Detected in many" "cerebral cortex: 136637375.6" HPA036223 Enhanced Supported Mitochondria No No 18000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 24: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 20: Non-specific - Transcription regulation" 21 Mitochondria "HPA036223: " "unprognostic (2.38e-2)" "unprognostic (4.18e-2)" "unprognostic (1.44e-1)" "unprognostic (9.57e-3)" "unprognostic (2.12e-1)" "unprognostic (3.31e-1)" "unprognostic (3.09e-1)" "unprognostic (5.24e-2)" "unprognostic (1.27e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (4.04e-5)" "unprognostic (5.99e-2)" "unprognostic (1.40e-3)" "unprognostic (8.66e-3)" "unprognostic (1.69e-1)" "unprognostic (7.42e-2)" "unprognostic (8.40e-2)" "unprognostic (1.75e-1)" "unprognostic (3.37e-2)" "unprognostic (5.11e-2)" "unprognostic (7.02e-2)" "unprognostic (2.85e-1)" "unprognostic (1.94e-3)" "unprognostic (2.56e-2)" "unprognostic (3.84e-2)" "unprognostic (6.16e-3)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "unprognostic (1.58e-1)" "unprognostic (7.90e-2)" "unprognostic (3.88e-3)" GLT8D2 FLJ31494 ENSG00000120820 "Glycosyltransferase 8 domain containing 2" Q9H1C3 12 103988987-104064183 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Breast myoepithelial cells: 77.5;Early spermatids: 38.7;Fibro-adipogenic progenitors: 72.7;Fibroblasts: 69.5;Late primary spermatocytes: 37.6;Leydig cells: 98.0;Lymphatic endothelial cells: 40.4;Mesothelial cells: 55.5;Ovarian stromal cells: 93.6;Peritubular myoid cells: 82.9;Somatotrophs: 45.5;Vascular smooth muscle cells: 40.5" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 72.7;Leydig cells: 98.0;Secretory gland support: 77.5;Stromal cells: 93.6" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 86.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Pancreatic islets: 411179.7" "Tissue enriched" "Detected in some" "ovary: 2198450.9" "HPA012740, HPA026904, HPA070791" Approved Approved "Golgi apparatus,Vesicles" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 94: Gonadal somatic cells - Mixed function" "Golgi apparatus, Vesicles" "HPA012740: , HPA026904: , HPA070791: " "unprognostic (2.77e-2)" "unprognostic (4.20e-1)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (2.19e-2)" "unprognostic (2.01e-1)" "unprognostic (2.13e-2)" "unprognostic (5.33e-3)" "unprognostic (1.36e-1)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (2.29e-3)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (2.74e-2)" "unprognostic (4.09e-2)" "unprognostic (3.80e-1)" "unprognostic (6.01e-2)" "unprognostic (3.18e-1)" "unprognostic (4.91e-2)" "unprognostic (7.55e-3)" "unprognostic (1.26e-3)" "unprognostic (5.64e-2)" "unprognostic (3.18e-1)" "unprognostic (9.86e-2)" "unprognostic (6.39e-2)" "unprognostic (8.53e-3)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (3.39e-2)" "unprognostic (6.25e-3)" "unprognostic (1.39e-1)" GLUD1 "GDH, GDH1, GLUD, hGDH1" ENSG00000148672 "Glutamate dehydrogenase 1" P00367 10 87050202-87094843 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "kidney: 265.0;liver: 860.3" "Cell type enhanced" "Detected in all" "Astrocytes: 574.1;Hepatocytes: 529.1;Respiratory basal cells: 572.5;Respiratory deuterosomal cells: 546.3;Respiratory secretory cells: 497.2" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "astrocyte: 607.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Cell type enhanced" "Detected in all" "Hepatocytes: 2707777448.9" "Group enriched" "Detected in all" "cerebral cortex: 592240317.8;liver: 1965089128.1" "HPA042492, HPA044839, HPA061369" Approved Supported Mitochondria NA NA 8100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 28: Astrocytes - Homeostasis & neuron support" 47 Mitochondria "HPA042492: , HPA044839: , HPA061369: " "unprognostic (1.53e-2)" "unprognostic (3.70e-2)" "unprognostic (1.55e-2)" "unprognostic (1.61e-1)" "unprognostic (3.15e-1)" "unprognostic (9.32e-2)" "unprognostic (7.94e-3)" "unprognostic (4.24e-3)" "unprognostic (4.46e-2)" "unprognostic (1.66e-1)" "potential prognostic favorable (1.27e-9)" "unprognostic (2.46e-2)" "unprognostic (6.92e-3)" "unprognostic (2.75e-2)" "unprognostic (1.84e-1)" "unprognostic (1.06e-1)" "unprognostic (2.87e-2)" "unprognostic (3.49e-2)" "unprognostic (1.61e-2)" "unprognostic (7.94e-3)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.67e-1)" "unprognostic (6.53e-2)" "unprognostic (9.83e-2)" "unprognostic (1.23e-1)" "unprognostic (4.05e-1)" "unprognostic (4.30e-1)" "unprognostic (5.69e-2)" "unprognostic (7.46e-2)" "unprognostic (9.46e-3)" GLUD2 GLUDP1 ENSG00000182890 "Glutamate dehydrogenase 2" P49448 X 121047610-121050094 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "liver: 3.7;testis: 14.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.2;Distal convoluted tubule cells: 1.2;Loop of henle epithelial cells: 1.6;Oligodendrocyte progenitor cells: 1.4;Podocytes: 1.0;Proximal tubule cells: 2.9;Renal collecting duct intercalated cells: 2.0" "Cell type enhanced" "Detected in some" "Ductal cells: 2.0;Glial cells: 1.4;Neuronal cells: 1.2;Renal nephron cells: 2.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Liver Hepatocellular Carcinoma (TCGA): 2.4;Skin Cutaneous Melanoma (TCGA): 2.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 3.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Testis - Sertoli cells" "Cell type enhanced" "Detected in many" "Glomeruli: 7946893.9;Proximal tubules: 8689141.9" "Group enriched" "Detected in some" "liver: 1501508.2;pancreas: 846559.8" "HPA042492, HPA044839, HPA061369" Uncertain Supported Mitochondria NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 105: Non-specific - Mixed function" 4 Mitochondria "HPA042492: , HPA044839: , HPA061369: " "unprognostic (5.63e-3)" "unprognostic (1.02e-2)" "potential prognostic favorable (1.24e-7)" "unprognostic (1.05e-1)" "unprognostic (1.85e-3)" "unprognostic (2.79e-3)" "unprognostic (3.50e-2)" "unprognostic (2.12e-1)" "unprognostic (3.81e-2)" GMNN Gem ENSG00000112312 "Geminin DNA replication inhibitor" O75496 6 24774931-24786099 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "DNA replication inhibitor" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 218.1" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 235.2;Endometrial luminal cells: 312.7;Enteric stem cells: 250.5;Enteric transient amplifying cells: 215.1;Late primary spermatocytes: 247.0;Oocytes: 432.9;Pancreatic duct cells: 215.2;Prostatic glandular cells: 197.4;Urothelial cells: 185.5" "Cell type enhanced" "Detected in many" "Luminal cells: 312.7;Oocytes: 432.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 258 "Granulosa cells: 25751.5" "Tissue enriched" "Detected in single" 9051 "bone marrow: 905087.8" "CAB011458, CAB047327, CAB047328, HPA049977, HPA054597" Enhanced Supported "Nucleoplasm,Basal body,Cytosol" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 8: Pancreas - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 34 Nucleoplasm "Basal body, Cytosol" "CAB011458: , CAB047327: , CAB047328: , HPA049977: , HPA054597: " "unprognostic (3.05e-2)" "unprognostic (5.99e-2)" "unprognostic (1.66e-2)" "unprognostic (5.47e-2)" "unprognostic (1.62e-1)" "unprognostic (7.64e-2)" "unprognostic (3.53e-2)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (2.49e-3)" "unprognostic (2.13e-3)" "unprognostic (4.95e-2)" "unprognostic (2.70e-3)" "unprognostic (8.39e-3)" "unprognostic (5.62e-3)" "unprognostic (1.73e-2)" "unprognostic (1.08e-2)" "unprognostic (5.22e-2)" "unprognostic (5.35e-2)" "unprognostic (2.41e-3)" "unprognostic (2.57e-1)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (8.31e-3)" "unprognostic (2.66e-2)" "unprognostic (1.77e-2)" "unprognostic (2.54e-1)" "unprognostic (3.55e-3)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (3.28e-2)" "unprognostic (1.20e-1)" GMPR2 ENSG00000100938 "Guanosine monophosphate reductase 2" Q9P2T1 14 24232422-24239242 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 12.0;Oligodendrocytes: 12.8;Other brain neurons: 13.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 18648774.8" "Low tissue specificity" "Detected in many" "HPA000904, HPA067884, HPA068782" Approved Approved Nucleoplasm,Nucleoli No No 110000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 6 Nucleoplasm Nucleoli "HPA000904: , HPA067884: , HPA068782: " "unprognostic (7.75e-2)" "unprognostic (1.77e-2)" "unprognostic (9.66e-3)" "unprognostic (1.64e-2)" "unprognostic (1.55e-1)" "unprognostic (2.57e-1)" "unprognostic (1.38e-2)" "unprognostic (2.08e-2)" "unprognostic (4.59e-3)" "unprognostic (5.76e-3)" "potential prognostic favorable (4.95e-7)" "unprognostic (6.27e-3)" "unprognostic (4.32e-2)" "unprognostic (9.73e-2)" "unprognostic (5.45e-2)" "unprognostic (7.41e-2)" "unprognostic (8.64e-2)" "unprognostic (9.12e-3)" "unprognostic (7.26e-3)" "unprognostic (2.02e-2)" "unprognostic (1.15e-1)" "unprognostic (7.19e-2)" "unprognostic (1.01e-1)" "unprognostic (9.12e-3)" "unprognostic (2.13e-1)" "unprognostic (2.11e-1)" "unprognostic (7.15e-3)" "unprognostic (2.11e-1)" "unprognostic (9.77e-2)" "unprognostic (4.30e-1)" "unprognostic (9.01e-2)" GMPS GATD7 ENSG00000163655 "Guanine monophosphate synthase" P49915 3 155870650-155944020 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" Ligase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 93.8" "Cell type enhanced" "Detected in all" "Early spermatids: 228.7;Late primary spermatocytes: 467.6;Late spermatids: 267.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 467.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in all" "skeletal muscle: 110412924.5" HPA046630 Supported Mitochondria,Cytosol No No 53000 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 10 "Mitochondria, Cytosol" "HPA046630: " "unprognostic (1.08e-2)" "unprognostic (2.82e-2)" "unprognostic (3.15e-1)" "unprognostic (1.16e-2)" "unprognostic (7.90e-3)" "unprognostic (2.30e-1)" "unprognostic (2.41e-1)" "unprognostic (6.78e-2)" "unprognostic (3.14e-2)" "unprognostic (6.53e-3)" "unprognostic (3.38e-3)" "unprognostic (7.38e-2)" "potential prognostic unfavorable (4.26e-4)" "validated prognostic unfavorable (3.28e-6)" "validated prognostic unfavorable (3.44e-5)" "validated prognostic unfavorable (1.26e-4)" "validated prognostic unfavorable (1.78e-4)" "unprognostic (2.06e-2)" "unprognostic (1.84e-1)" "unprognostic (5.98e-2)" "unprognostic (4.20e-2)" "validated prognostic unfavorable (6.88e-6)" "validated prognostic unfavorable (3.90e-4)" "unprognostic (2.29e-3)" "unprognostic (8.73e-2)" "unprognostic (8.60e-2)" "unprognostic (1.97e-2)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (3.39e-3)" GNAI1 ENSG00000127955 "G protein subunit alpha i1" P63096 7 79768028-80226181 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Transport" "Hydrolase, Transducer" "Cancer-related genes, Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1" "Cell type enhanced" "Detected in many" "Adipocytes: 280.6;Basal keratinocytes: 317.3;Loop of henle epithelial cells: 253.1;Oligodendrocytes: 505.9;Suprabasal keratinocytes: 295.5;Syncytiotrophoblasts: 280.5" "Cell type enhanced" "Detected in all" "Glial cells: 505.9" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 494.9;oligodendrocyte: 625.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "NK-cell: 12.8" "Lineage enriched" "Detected in many" 6 "NK-cells: 12.8" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Lung - Fibroblasts_1, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 49222235.8;Microglia and Neuropil: 35581498.7" "Tissue enriched" "Detected in all" "cerebral cortex: 77194797.0" "CAB022449, HPA042141" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Centriolar satellite,Centrosome,Basal body,Cytosol,Principal piece" NA NA 1900000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 38 "Centrosome, Principal piece" "Nucleoplasm, Nucleoli, Golgi apparatus, Centriolar satellite, Basal body, Cytosol" "CAB022449: , HPA042141: " "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (1.46e-3)" "unprognostic (2.68e-1)" "unprognostic (1.73e-1)" "unprognostic (8.33e-2)" "potential prognostic favorable (6.96e-4)" "unprognostic (3.39e-1)" "unprognostic (2.42e-2)" "validated prognostic favorable (4.69e-5)" "validated prognostic favorable (5.00e-4)" "unprognostic (4.65e-2)" "unprognostic (2.24e-2)" "unprognostic (1.01e-2)" "unprognostic (3.11e-3)" "unprognostic (2.14e-1)" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (5.63e-2)" "unprognostic (1.02e-1)" "unprognostic (5.69e-2)" "unprognostic (8.31e-3)" "unprognostic (3.13e-1)" "unprognostic (2.10e-1)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (1.51e-4)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (9.80e-2)" "unprognostic (1.81e-2)" "unprognostic (1.75e-1)" GNAI2 "GIP, GNAI2B" ENSG00000114353 "G protein subunit alpha i2" P04899 3 50226292-50259362 "Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 484.1;Late spermatids: 487.7;Monocyte progenitors: 498.2;monocytes: 676.1;Neutrophil progenitors: 445.2;Neutrophils: 1060.3" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 676.1;Neutrophils: 1060.3" "Cell type enhanced" "Detected in all" "endothelial cell: 265.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Lung - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA007704 Approved Supported "Nucleoplasm,Plasma membrane,Basal body,Cytosol" NA NA 7300000 "Cluster 7: Non-specific - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 38 Cytosol "Nucleoplasm, Plasma membrane, Basal body" "HPA007704: " "unprognostic (3.03e-2)" "unprognostic (1.47e-2)" "unprognostic (2.01e-1)" "unprognostic (9.59e-2)" "unprognostic (2.19e-1)" "unprognostic (1.26e-1)" "unprognostic (4.03e-1)" "unprognostic (2.88e-2)" "unprognostic (1.08e-1)" "unprognostic (4.76e-2)" "potential prognostic favorable (7.04e-4)" "unprognostic (5.58e-3)" "unprognostic (3.41e-1)" "unprognostic (3.18e-3)" "unprognostic (1.05e-1)" "unprognostic (1.62e-1)" "unprognostic (5.28e-3)" "unprognostic (7.12e-2)" "unprognostic (8.62e-2)" "unprognostic (1.50e-1)" "unprognostic (5.47e-1)" "unprognostic (1.58e-1)" "unprognostic (4.70e-2)" "unprognostic (3.07e-1)" "unprognostic (1.94e-2)" "unprognostic (6.37e-3)" "unprognostic (4.49e-2)" "unprognostic (8.58e-2)" "unprognostic (5.15e-2)" "unprognostic (3.37e-1)" "unprognostic (1.80e-1)" GNAI3 87U6 ENSG00000065135 "G protein subunit alpha i3" P08754 1 109548615-109600195 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 759.6;Neutrophils: 1086.0" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 759.6;Neutrophils: 1086.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "CAB022099, HPA042141" Approved Supported "Nucleoplasm,Nucleoli,Golgi apparatus,Centriolar satellite,Centrosome,Basal body,Cytosol,Principal piece" NA NA 1800000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 53 "Centrosome, Principal piece" "Nucleoplasm, Nucleoli, Golgi apparatus, Centriolar satellite, Basal body, Cytosol" "CAB022099: , HPA042141: " "unprognostic (7.77e-2)" "unprognostic (1.82e-1)" "unprognostic (3.44e-2)" "unprognostic (7.22e-2)" "potential prognostic favorable (3.29e-4)" "unprognostic (3.55e-1)" "unprognostic (2.75e-1)" "unprognostic (5.34e-1)" "unprognostic (6.80e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (5.45e-7)" "unprognostic (7.14e-3)" "unprognostic (1.87e-1)" "validated prognostic unfavorable (1.71e-6)" "validated prognostic unfavorable (3.93e-4)" "validated prognostic unfavorable (4.05e-4)" "validated prognostic unfavorable (3.95e-4)" "unprognostic (2.27e-1)" "unprognostic (1.78e-1)" "unprognostic (6.66e-3)" "unprognostic (1.79e-2)" "unprognostic (1.36e-3)" "unprognostic (8.31e-2)" "unprognostic (7.05e-2)" "unprognostic (3.27e-2)" "unprognostic (1.75e-1)" "unprognostic (8.96e-2)" "unprognostic (1.94e-1)" "unprognostic (2.42e-1)" "unprognostic (4.14e-3)" "unprognostic (7.66e-2)" GNAT1 CSNBAD3 ENSG00000114349 "G protein subunit alpha transducin 1" P11488 3 50191610-50197696 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 944 "retina: 1040.7" "Cell type enriched" "Detected in some" 16 "Rod photoreceptor cells: 1217.2" "Cell type enriched" "Detected in some" 16 "Neuronal cells: 1217.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in some" 6 "hippocampal formation: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045393 Enhanced Approved "Mid piece,Principal piece,End piece" NA NA "Cluster 42: Retina - Visual perception" "Cluster 9: Non-specific - Receptor signaling" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Mid piece, Principal piece, End piece" "HPA045393: " "unprognostic (1.58e-1)" "unprognostic (1.03e-2)" GNL2 "HUMAUANTIG, Ngp-1, Nog2, Nug2" ENSG00000134697 "G protein nucleolar 2" Q13823 1 37566816-37595937 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 152.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in some" "intestine: 586825.4" "HPA027163, HPA060026" Approved Supported "Nucleoli,Nucleoli rim" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 113 "Nucleoli, Nucleoli rim" "HPA027163: , HPA060026: " "unprognostic (2.15e-1)" "unprognostic (8.71e-2)" "unprognostic (5.80e-2)" "unprognostic (4.88e-2)" "unprognostic (1.34e-2)" "unprognostic (1.71e-1)" "unprognostic (2.73e-1)" "unprognostic (2.48e-2)" "unprognostic (2.56e-2)" "unprognostic (9.52e-3)" "unprognostic (3.40e-2)" "unprognostic (3.26e-1)" "unprognostic (3.98e-3)" "validated prognostic unfavorable (2.47e-12)" "validated prognostic unfavorable (3.42e-5)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (1.32e-1)" "unprognostic (1.23e-1)" "unprognostic (1.48e-2)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (9.01e-2)" "unprognostic (1.87e-2)" "unprognostic (1.60e-1)" "unprognostic (1.90e-1)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (2.54e-2)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" GNL3 "C77032, E2IG3, MGC800, NS" ENSG00000163938 "G protein nucleolar 3" Q9BVP2 3 52681156-52694497 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 382.8;Prostatic club cells: 248.7;Urothelial cells: 281.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 382.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB020770, HPA036742, HPA036743" Enhanced Enhanced "Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 69: Urothelial cells - Basic cellular functions" 97 "Nucleoli rim" "Nuclear bodies, Mitotic chromosome" "CAB020770: , HPA036742: , HPA036743: " "unprognostic (7.45e-2)" "unprognostic (6.93e-2)" "unprognostic (1.69e-1)" "unprognostic (1.74e-1)" "unprognostic (8.96e-3)" "unprognostic (2.55e-1)" "unprognostic (1.52e-1)" "unprognostic (1.28e-1)" "unprognostic (7.17e-2)" "unprognostic (1.02e-2)" "unprognostic (3.71e-2)" "unprognostic (1.03e-1)" "unprognostic (2.88e-3)" "validated prognostic unfavorable (7.31e-6)" "validated prognostic unfavorable (2.81e-4)" "unprognostic (1.96e-2)" "potential prognostic unfavorable (7.80e-7)" "unprognostic (1.14e-2)" "unprognostic (9.19e-2)" "unprognostic (8.80e-3)" "unprognostic (3.50e-1)" "unprognostic (1.22e-2)" "unprognostic (2.29e-2)" "unprognostic (1.67e-3)" "unprognostic (5.28e-3)" "unprognostic (3.49e-1)" "unprognostic (1.95e-2)" "unprognostic (1.34e-1)" "unprognostic (3.81e-1)" "unprognostic (3.52e-3)" "unprognostic (1.63e-2)" GNPAT "DAP-AT, DAPAT, DHAPAT" ENSG00000116906 "Glyceronephosphate O-acyltransferase" O15228 1 231241207-231277973 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Cataract, Disease variant, Dwarfism, Rhizomelic chondrodysplasia punctata" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 214.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 214.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Cardiomyocytes: 1850182.6;Keratinocytes: 495659.2;Neutrophils: 958044.5;Pancreas epithelial cells: 1765287.5" "Group enriched" "Detected in many" "fallopian tube: 849707.4;intestine: 1150593.2;lung: 1115850.0;salivary gland: 646250.4" HPA039130 Approved "Vesicles,Cell Junctions" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 "Vesicles, Cell Junctions" "HPA039130: " "unprognostic (1.34e-1)" "unprognostic (1.41e-1)" "unprognostic (3.97e-1)" "unprognostic (2.02e-2)" "unprognostic (1.61e-2)" "unprognostic (1.84e-2)" "unprognostic (9.82e-2)" "unprognostic (1.56e-2)" "unprognostic (1.57e-1)" "unprognostic (7.78e-3)" "potential prognostic favorable (5.37e-4)" "unprognostic (9.73e-2)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (2.33e-2)" "unprognostic (5.47e-2)" "unprognostic (5.91e-2)" "unprognostic (5.33e-2)" "unprognostic (2.26e-1)" "unprognostic (2.34e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.28e-2)" "unprognostic (9.95e-2)" "unprognostic (3.56e-1)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (3.34e-3)" "unprognostic (8.54e-2)" "unprognostic (2.36e-1)" "unprognostic (6.51e-2)" "unprognostic (7.02e-3)" "unprognostic (2.30e-1)" GNPTAB "GNPTA, KIAA1208, MGC4170" ENSG00000111670 "N-acetylglucosamine-1-phosphate transferase subunits alpha and beta" Q3T906 12 101745499-101830959 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Transferase "Cancer-related genes, Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 771.1;Lacrimal acinar cells: 444.8;Mast cells: 400.7;NK-cells: 335.5;Prostatic club cells: 521.6" "Cell type enhanced" "Detected in many" "Myocytes: 771.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Thyrotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 81556.3;Pancreatic islets: 108333.7" "Tissue enriched" "Detected in some" "lymphoid tissue: 2661683.7" "HPA014558, HPA042343" Approved Supported "Golgi apparatus" NA NA 63000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 "Golgi apparatus" "HPA014558: , HPA042343: " "unprognostic (6.98e-3)" "unprognostic (1.12e-1)" "unprognostic (1.44e-1)" "unprognostic (2.21e-1)" "unprognostic (2.23e-2)" "unprognostic (9.92e-2)" "unprognostic (7.49e-2)" "unprognostic (2.44e-1)" "unprognostic (1.80e-1)" "unprognostic (6.97e-2)" "potential prognostic favorable (3.36e-5)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (1.67e-1)" "unprognostic (1.62e-1)" "unprognostic (6.29e-2)" "unprognostic (4.60e-1)" "unprognostic (7.81e-2)" "unprognostic (4.12e-2)" "unprognostic (1.48e-2)" "unprognostic (1.26e-3)" "unprognostic (5.05e-2)" "unprognostic (1.16e-1)" "unprognostic (1.39e-1)" "unprognostic (8.50e-2)" "unprognostic (4.48e-1)" "unprognostic (6.47e-2)" "unprognostic (3.68e-1)" "unprognostic (4.40e-1)" "unprognostic (1.21e-1)" "unprognostic (2.85e-1)" GOLGA1 "golgin-97, MGC33154" ENSG00000136935 "Golgin A1" Q92805 9 124878275-124948492 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 186.3;Rod photoreceptor cells: 153.9" "Cell type enhanced" "Detected in many" "Neuronal cells: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 7022273.5" "Tissue enriched" "Detected in many" "intestine: 11897941.7" "CAB013065, HPA044329, HPA050555" Supported Enhanced "Golgi apparatus" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 79: Photoreceptor cells - Phototransduction" 13 "Golgi apparatus" "CAB013065: , HPA044329: , HPA050555: " "unprognostic (1.09e-1)" "unprognostic (7.04e-3)" "unprognostic (3.71e-2)" "unprognostic (3.13e-2)" "unprognostic (1.86e-1)" "unprognostic (2.52e-3)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (5.66e-2)" "unprognostic (1.37e-1)" "potential prognostic favorable (5.02e-6)" "unprognostic (7.41e-3)" "unprognostic (7.92e-2)" "unprognostic (4.30e-1)" "unprognostic (7.89e-2)" "unprognostic (3.81e-1)" "unprognostic (1.27e-1)" "unprognostic (2.12e-2)" "unprognostic (1.08e-1)" "unprognostic (2.95e-2)" "unprognostic (3.04e-1)" "unprognostic (8.65e-2)" "unprognostic (6.43e-2)" "unprognostic (2.01e-1)" "unprognostic (2.99e-3)" "unprognostic (7.36e-2)" "unprognostic (9.93e-2)" "unprognostic (6.78e-3)" "unprognostic (1.65e-1)" "unprognostic (7.41e-3)" "unprognostic (2.74e-1)" GOLGA6A "GLP, GOLGA6" ENSG00000159289 "Golgin A6 family member A" Q9NYA3 15 74069857-74082550 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 12.2" "Group enriched" "Detected in some" 12 "Early spermatids: 27.9;Late primary spermatocytes: 20.7" "Cell type enriched" "Detected in single" 31 "Spermatogenic cell types: 27.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 47: Testis - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 39 Vesicles "Nucleoplasm, Centrosome" "HPA044978: , HPA050087: , HPA072134: " GOLGA6B ENSG00000215186 "Golgin A6 family member B" A6NDN3 15 72654697-72669599 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 13 "liver: 4.0;testis: 6.1" "Group enriched" "Detected in some" 5 "Early spermatids: 9.8;Late primary spermatocytes: 7.0;Retinal pigment epithelial cells: 4.3" "Group enriched" "Detected in some" 5 "Pigment cells: 4.3;Spermatogenic cell types: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 47: Testis - Mixed function" "Cluster 20: Myeloma - Immune response" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "Nucleoplasm, Centrosome" "HPA044978: , HPA050087: , HPA072134: " GOLGA6C ENSG00000167195 "Golgin A6 family member C" A6NDK9 15 75258334-75273455 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 7 "liver: 3.5;testis: 11.5" "Group enriched" "Detected in some" 8 "Early spermatids: 34.8;Late primary spermatocytes: 24.1" "Cell type enriched" "Detected in some" 31 "Spermatogenic cell types: 34.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 47: Testis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "Nucleoplasm, Centrosome" "HPA044978: , HPA050087: , HPA072134: " "unprognostic (6.48e-3)" GOLGA6D ENSG00000140478 "Golgin A6 family member D" P0CG33 15 75282835-75295807 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 6.2" "Cell type enhanced" "Detected in some" "Early spermatids: 11.4;Late primary spermatocytes: 9.6;Late spermatids: 2.7" "Cell type enriched" "Detected in single" 39 "Spermatogenic cell types: 11.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044978, HPA050087, HPA072134" Supported Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" Vesicles "Nucleoplasm, Centrosome" "HPA044978: , HPA050087: , HPA072134: " GOLGA8A "CFAP286, FAP286, GM88, GOLGIN-67" ENSG00000175265 "Golgin A8 family member A" A7E2F4 15 34378935-34437808 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 189.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Not detected" "Not detected" HPA051808 Approved Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 22: Epididymis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Golgi apparatus" Cytosol "HPA051808: " "unprognostic (1.31e-1)" "unprognostic (1.83e-1)" "unprognostic (3.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.18e-2)" "unprognostic (5.17e-2)" "unprognostic (9.34e-3)" "unprognostic (1.52e-3)" "unprognostic (6.17e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (1.79e-5)" "unprognostic (1.33e-2)" "unprognostic (7.06e-2)" "unprognostic (1.16e-2)" "unprognostic (3.30e-2)" "unprognostic (3.52e-2)" "unprognostic (2.81e-1)" "unprognostic (3.56e-3)" "unprognostic (3.22e-1)" "unprognostic (1.43e-1)" "unprognostic (2.10e-1)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (1.13e-1)" "unprognostic (9.88e-2)" "unprognostic (2.29e-2)" "unprognostic (7.54e-2)" "unprognostic (2.58e-1)" "unprognostic (1.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.69e-2)" GOLGA8B ENSG00000215252 "Golgin A8 family member B" A8MQT2 15 34525095-34588503 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "pancreas: 193.0" "Cell type enhanced" "Detected in many" "Gonadotrophs: 171.1;Podocytes: 166.0;Sertoli cells: 188.6;Somatotrophs: 200.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 41.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA051808 Approved Approved "Golgi apparatus,Cytosol" NA Yes "Cluster 70: Non-specific - Protein processing" "Cluster 35: Non-specific - DNA binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 9: T-cells - Adaptive immunity: Regulation" "Golgi apparatus" Cytosol "HPA051808: " "unprognostic (7.10e-2)" "unprognostic (3.01e-2)" "unprognostic (1.44e-1)" "unprognostic (5.31e-2)" "unprognostic (1.92e-1)" "unprognostic (2.47e-1)" "unprognostic (9.94e-3)" "unprognostic (4.81e-2)" "unprognostic (8.71e-2)" "potential prognostic unfavorable (6.66e-9)" "unprognostic (9.23e-2)" "unprognostic (1.44e-1)" "unprognostic (1.71e-2)" "unprognostic (3.15e-2)" "unprognostic (4.58e-2)" "unprognostic (2.44e-1)" "unprognostic (2.62e-1)" "unprognostic (1.35e-1)" "unprognostic (1.45e-1)" "unprognostic (1.74e-2)" "unprognostic (2.75e-3)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (1.22e-2)" "unprognostic (1.74e-2)" "unprognostic (2.89e-1)" "unprognostic (3.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.67e-1)" "unprognostic (6.00e-3)" GOPC "CAL, dJ94G16.2, FIG, GOPC1, PIST" ENSG00000047932 "Golgi associated PDZ and coiled-coil motif containing" Q9HD26 6 117560269-117602542 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA019477, HPA024018" Approved Supported "Golgi apparatus,Calyx,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 60 "Golgi apparatus" "Calyx, Connecting piece, Mid piece, Principal piece" "HPA019477: , HPA024018: " "unprognostic (2.41e-1)" "unprognostic (9.23e-3)" "unprognostic (1.05e-1)" "unprognostic (6.93e-3)" "unprognostic (2.16e-1)" "unprognostic (1.28e-1)" "unprognostic (2.89e-2)" "unprognostic (3.71e-2)" "unprognostic (2.02e-1)" "unprognostic (9.80e-3)" "unprognostic (2.78e-3)" "unprognostic (1.88e-2)" "unprognostic (3.00e-1)" "unprognostic (2.86e-3)" "unprognostic (6.78e-2)" "unprognostic (9.55e-3)" "unprognostic (1.87e-1)" "unprognostic (1.46e-1)" "unprognostic (1.31e-1)" "unprognostic (2.19e-2)" "unprognostic (1.22e-3)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (4.14e-4)" "unprognostic (6.55e-2)" "unprognostic (3.01e-2)" "unprognostic (2.31e-1)" "unprognostic (2.11e-1)" "unprognostic (5.72e-3)" "unprognostic (3.57e-1)" "unprognostic (2.20e-1)" "unprognostic (3.37e-2)" GPAA1 "GAA1, hGAA1" ENSG00000197858 "Glycosylphosphatidylinositol anchor attachment 1" O43292 8 144082337-144093149 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 257.4;Extravillous trophoblasts: 196.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 257.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" HPA077224 Approved Approved "Endoplasmic reticulum,Centrosome,Mitochondria,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 30 "Endoplasmic reticulum, Cytosol" "Centrosome, Mitochondria" "HPA077224: " "unprognostic (1.63e-2)" "potential prognostic unfavorable (4.02e-4)" "unprognostic (2.01e-1)" "unprognostic (1.20e-2)" "unprognostic (2.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.44e-1)" "unprognostic (2.02e-2)" "unprognostic (3.31e-1)" "unprognostic (6.82e-2)" "unprognostic (6.86e-2)" "unprognostic (1.72e-1)" "unprognostic (3.86e-1)" "unprognostic (3.64e-3)" "unprognostic (3.16e-2)" "unprognostic (4.52e-2)" "unprognostic (3.02e-2)" "unprognostic (4.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (6.18e-4)" "unprognostic (5.60e-2)" "unprognostic (4.21e-3)" "unprognostic (5.78e-2)" "unprognostic (1.82e-1)" "unprognostic (2.74e-2)" "unprognostic (2.63e-1)" "unprognostic (7.80e-2)" "unprognostic (1.10e-1)" "unprognostic (1.76e-1)" "unprognostic (4.23e-2)" GPALPP1 "AD029, bA245H20.2, KIAA1704, LSR7" ENSG00000133114 "GPALPP motifs containing 1" Q8IXQ4 13 44989529-45037669 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1921679.8" "Tissue enriched" "Detected in many" "lung: 8218382.6" "HPA038966, HPA058739" Enhanced Approved "Nucleoplasm,Nucleoli rim" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Nucleoli rim" Nucleoplasm "HPA038966: , HPA058739: " "unprognostic (1.31e-1)" "unprognostic (3.02e-1)" "unprognostic (3.86e-2)" "unprognostic (1.40e-1)" "unprognostic (1.51e-1)" "unprognostic (2.74e-1)" "unprognostic (4.07e-1)" "unprognostic (1.41e-1)" "unprognostic (3.41e-3)" "unprognostic (1.15e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (3.91e-1)" "unprognostic (1.06e-1)" "unprognostic (1.20e-2)" "unprognostic (2.11e-1)" "unprognostic (2.70e-2)" "unprognostic (1.05e-1)" "unprognostic (2.37e-3)" "unprognostic (2.29e-3)" "unprognostic (4.67e-1)" "unprognostic (2.42e-3)" "unprognostic (2.81e-1)" "unprognostic (1.43e-3)" "unprognostic (1.43e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-1)" GPIHBP1 "GPI-HBP1, LOC338328" ENSG00000277494 "Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1" Q8IV16 8 143213218-143217170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 85.2;brain: 70.0;breast: 53.2" "Group enriched" "Detected in some" 12 "Lymphatic endothelial cells: 28.5;Oligodendrocytes: 23.3;Vascular endothelial cells: 71.9" "Group enriched" "Detected in some" 14 "Endothelial cells: 71.9;Glial cells: 23.3" "Group enriched" "Detected in some" 7 "endothelial cell: 32.9;oligodendrocyte: 34.6" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA066302 Enhanced Approved "Principal piece,End piece" "Intracellular and membrane" Transport NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 7: Liver cancer - Metabolism" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 "End piece" "Principal piece" "HPA066302: " "unprognostic (1.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.98e-2)" "unprognostic (3.48e-1)" "unprognostic (1.17e-1)" "validated prognostic favorable (2.82e-7)" "validated prognostic favorable (6.70e-4)" "unprognostic (1.49e-1)" "unprognostic (2.05e-3)" "unprognostic (2.05e-2)" "unprognostic (1.13e-2)" "unprognostic (1.58e-1)" "unprognostic (2.17e-3)" "unprognostic (1.60e-1)" "unprognostic (1.10e-1)" "unprognostic (9.80e-2)" "unprognostic (1.39e-1)" "unprognostic (4.19e-2)" GPKOW "GPATC5, GPATCH5, Mos2, Spp2, T54" ENSG00000068394 "G-patch domain and KOW motifs" Q92917 X 49113407-49123735 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 59.9;Syncytiotrophoblasts: 54.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 6166678.3" "Tissue enhanced" "Detected in many" "intestine: 4702563.7" "HPA000287, HPA001894" Enhanced Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 69 Nucleoplasm "HPA000287: , HPA001894: " "unprognostic (2.81e-1)" "unprognostic (9.72e-3)" "unprognostic (6.09e-2)" "unprognostic (7.24e-2)" "unprognostic (1.84e-1)" "unprognostic (3.82e-1)" "unprognostic (2.19e-1)" "potential prognostic favorable (2.73e-6)" "unprognostic (1.16e-1)" "unprognostic (9.98e-3)" "potential prognostic favorable (2.45e-4)" "unprognostic (4.35e-2)" "unprognostic (3.06e-1)" "validated prognostic unfavorable (7.62e-4)" "validated prognostic unfavorable (1.95e-4)" "unprognostic (2.54e-2)" "unprognostic (7.36e-2)" "unprognostic (4.82e-2)" "unprognostic (2.33e-1)" "unprognostic (1.95e-1)" "unprognostic (1.20e-1)" "unprognostic (1.48e-1)" "unprognostic (3.38e-1)" "unprognostic (2.47e-1)" "unprognostic (7.86e-2)" "unprognostic (1.05e-1)" "unprognostic (2.60e-1)" "unprognostic (9.48e-2)" "unprognostic (1.81e-1)" "unprognostic (3.50e-1)" "unprognostic (1.02e-1)" GPN3 "ATPBD1C, MGC14560" ENSG00000111231 "GPN-loop GTPase 3" Q9UHW5 12 110452486-110469268 "Essential proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 139.9;Hofbauer cells: 140.8;Late primary spermatocytes: 235.8" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 235.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 56.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1467 "Oocytes: 146670.1" "Tissue enriched" "Detected in single" 13 "lymphoid tissue: 1288.5" "HPA039764, HPA047793" Uncertain Approved "Nuclear speckles,Cytosol" Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 49 "Nuclear speckles" Cytosol "HPA039764: , HPA047793: " "unprognostic (2.28e-2)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (1.98e-2)" "unprognostic (1.39e-2)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.53e-1)" "unprognostic (4.69e-3)" "unprognostic (6.81e-2)" "potential prognostic favorable (5.15e-8)" "unprognostic (3.54e-3)" "unprognostic (5.73e-2)" "validated prognostic unfavorable (6.10e-5)" "validated prognostic unfavorable (5.35e-6)" "unprognostic (2.11e-2)" "unprognostic (2.97e-2)" "unprognostic (5.88e-2)" "unprognostic (6.44e-2)" "unprognostic (2.22e-1)" "unprognostic (1.10e-3)" "unprognostic (9.31e-2)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (5.64e-2)" "unprognostic (2.73e-2)" "unprognostic (2.23e-2)" "unprognostic (7.12e-2)" "unprognostic (4.83e-2)" "unprognostic (4.19e-1)" "unprognostic (3.13e-1)" "unprognostic (2.75e-2)" GPR108 LUSTR2 ENSG00000125734 "G protein-coupled receptor 108" Q9NPR9 19 6729914-6737580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 102.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 102.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Pancreas epithelial cells: 6036973.6;Pancreatic islets: 8662048.7" "Group enriched" "Detected in many" "intestine: 280467.4;pancreas: 478457.0;salivary gland: 197324.6" "HPA041924, HPA041951, HPA063863" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 8 "Golgi apparatus" Vesicles "HPA041924: , HPA041951: , HPA063863: " "unprognostic (1.40e-1)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (3.56e-1)" "unprognostic (7.39e-2)" "unprognostic (1.79e-2)" "unprognostic (1.33e-1)" "unprognostic (3.20e-1)" "unprognostic (6.02e-3)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.26e-11)" "unprognostic (9.90e-3)" "unprognostic (1.06e-1)" "unprognostic (4.32e-2)" "unprognostic (2.24e-2)" "unprognostic (8.49e-2)" "unprognostic (7.65e-2)" "unprognostic (1.70e-1)" "unprognostic (3.50e-1)" "unprognostic (1.70e-1)" "unprognostic (6.73e-2)" "unprognostic (1.65e-1)" "unprognostic (2.09e-1)" "unprognostic (8.03e-2)" "unprognostic (1.14e-1)" "unprognostic (2.60e-1)" "unprognostic (4.06e-2)" "unprognostic (2.18e-1)" "unprognostic (1.09e-2)" "unprognostic (1.16e-2)" "unprognostic (1.20e-1)" GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "HPA046655: , HPA060527: " GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 102.0;parathyroid gland: 203.7;retina: 96.9" "Cell type enhanced" "Detected in many" "Enteric stem cells: 293.5;Enteric transient amplifying cells: 238.9;Enterocytes: 406.4;Gastric chief cells: 338.5;Gastric progenitor cells: 230.7;Mucous neck cells: 210.2;Neuroendocrine cells: 277.7;Neutrophil progenitors: 252.4;Neutrophils: 407.0;Paneth cells: 243.6;Rod photoreceptor cells: 675.4" "Cell type enhanced" "Detected in many" "Enterocytes: 406.4;Neuronal cells: 675.4;Neutrophils: 407.0" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 41.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "Plasma membrane" "HPA006970: " "potential prognostic favorable (4.25e-5)" "unprognostic (5.67e-2)" "unprognostic (2.17e-1)" "unprognostic (7.78e-2)" "unprognostic (6.28e-2)" "unprognostic (6.02e-2)" "unprognostic (7.42e-2)" "unprognostic (3.55e-1)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (1.18e-5)" "potential prognostic favorable (1.23e-8)" "unprognostic (1.17e-2)" "unprognostic (9.73e-3)" "unprognostic (1.06e-2)" "unprognostic (6.81e-2)" "unprognostic (1.40e-2)" "unprognostic (4.91e-2)" "unprognostic (2.55e-3)" "unprognostic (9.29e-2)" "unprognostic (2.54e-1)" "unprognostic (1.54e-1)" "unprognostic (2.14e-2)" "unprognostic (4.24e-2)" "unprognostic (5.51e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (2.08e-1)" "unprognostic (1.18e-1)" "unprognostic (4.17e-1)" "unprognostic (1.96e-1)" "unprognostic (4.26e-2)" "unprognostic (5.23e-3)" GPR180 ITR ENSG00000152749 "G protein-coupled receptor 180" Q86V85 13 94601857-94634661 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 1054988.8;Pancreatic islets: 1276742.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10368.9" HPA047250 Approved Approved "Nucleoplasm,Vesicles,Primary cilium" NA NA 8400 "Cluster 1: T-cells - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 10 Vesicles "Nucleoplasm, Primary cilium" "HPA047250: " "unprognostic (2.33e-1)" "unprognostic (1.69e-2)" "unprognostic (1.03e-1)" "unprognostic (1.38e-1)" "unprognostic (7.55e-2)" "unprognostic (1.72e-1)" "unprognostic (2.36e-1)" "unprognostic (1.21e-1)" "unprognostic (1.26e-1)" "unprognostic (1.86e-2)" "unprognostic (1.14e-2)" "unprognostic (1.09e-1)" "unprognostic (2.04e-2)" "unprognostic (1.33e-2)" "unprognostic (7.02e-2)" "unprognostic (1.90e-2)" "unprognostic (1.55e-2)" "unprognostic (1.03e-1)" "unprognostic (1.35e-1)" "unprognostic (9.02e-2)" "unprognostic (4.20e-2)" "unprognostic (1.08e-1)" "unprognostic (6.74e-3)" "unprognostic (1.53e-1)" "unprognostic (1.17e-1)" "unprognostic (3.24e-1)" "unprognostic (2.11e-2)" "unprognostic (7.74e-2)" "unprognostic (1.61e-1)" "unprognostic (3.18e-2)" "unprognostic (8.40e-2)" GPR183 EBI2 ENSG00000169508 "G protein-coupled receptor 183" P32249 13 99294539-99307399 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.3;lymphoid tissue: 79.7" "Cell type enhanced" "Detected in many" "B-cells: 302.1;cDC: 1208.2;Innate lymphoid cells: 192.6;Macrophages: 786.0;Microglia: 155.1;monocytes: 811.1;pDCs: 915.2;T-cells: 230.7" "Cell type enhanced" "Detected in many" "B-cells: 302.1;dendritic cells: 1208.2;Mononuclear phagocytes: 811.1" "Group enriched" "Detected in many" 38 "central nervous system macrophage: 216.7;leukocyte: 58.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1054.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 14.9;lymphoma: 23.7;thyroid cancer: 22.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 536 "B-cells: 54868.3;T-cells: 52277.1" "Tissue enriched" "Detected in single" 44 "lymphoid tissue: 4384.1" "CAB033690, HPA075590" Approved Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Plasma membrane" "Nucleoplasm, Primary cilium, Primary cilium tip" "CAB033690: , HPA075590: " "unprognostic (1.37e-1)" "unprognostic (1.17e-2)" "unprognostic (9.70e-2)" "unprognostic (8.63e-3)" "unprognostic (9.49e-2)" "unprognostic (6.11e-2)" "unprognostic (1.81e-1)" "unprognostic (1.54e-1)" "unprognostic (3.52e-2)" "unprognostic (1.62e-1)" "unprognostic (3.18e-1)" "unprognostic (2.84e-1)" "unprognostic (9.90e-2)" "unprognostic (1.07e-1)" "unprognostic (1.88e-2)" "unprognostic (5.47e-3)" "unprognostic (1.89e-1)" "unprognostic (1.04e-1)" "unprognostic (3.21e-2)" "unprognostic (6.80e-2)" "unprognostic (1.65e-1)" "unprognostic (7.41e-2)" "unprognostic (2.60e-1)" "unprognostic (2.77e-1)" "unprognostic (1.51e-1)" "unprognostic (4.95e-3)" "unprognostic (2.46e-1)" "unprognostic (3.13e-3)" "unprognostic (2.97e-3)" "unprognostic (5.62e-3)" "unprognostic (2.58e-1)" GPR37 "EDNRBL, hET(B)R-LP, PAELR" ENSG00000170775 "G protein-coupled receptor 37" O15354 7 124743885-124765792 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 67.2;retina: 36.2" "Group enriched" "Detected in many" 7 "Müller glia: 787.4;Oligodendrocytes: 380.2" "Cell type enriched" "Detected in many" 9 "Glial cells: 787.4" "Cell type enriched" "Detected in all" 4 "oligodendrocyte: 466.1" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 17.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 7.4" "Colon - Colon enteroendocrine cells, Liver - Hepatocytes, Skin - Inner root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13350 "Astrocytes and Neuropil: 1467401.7;Microglia and Neuropil: 508999.2;Neurons: 2028722.7" "Tissue enriched" "Detected in single" 10780 "cerebral cortex: 1078041.8" "HPA042903, HPA068009" Approved Uncertain "Nuclear membrane,Nucleoli,Cytosol" No No 2700000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 11: Muller glia cells - Retinal homeostasis" 41 "Nuclear membrane" "Nucleoli, Cytosol" "HPA042903: , HPA068009: " "unprognostic (6.59e-2)" "unprognostic (1.88e-1)" "unprognostic (1.00e-1)" "unprognostic (2.82e-1)" "unprognostic (6.79e-2)" "unprognostic (2.22e-2)" "unprognostic (5.68e-2)" "unprognostic (2.43e-1)" "unprognostic (6.88e-2)" "unprognostic (3.51e-1)" "unprognostic (9.41e-2)" "unprognostic (2.38e-1)" "unprognostic (2.40e-2)" "validated prognostic unfavorable (8.72e-5)" "validated prognostic unfavorable (9.13e-4)" "unprognostic (1.68e-2)" "unprognostic (1.33e-2)" "unprognostic (1.11e-3)" "unprognostic (6.61e-3)" "potential prognostic unfavorable (8.70e-4)" "unprognostic (1.49e-1)" "unprognostic (5.55e-2)" "unprognostic (1.05e-1)" "unprognostic (4.15e-2)" GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176584-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 16 "pituitary gland: 15.6" "Cell type enriched" "Detected in single" 15 "Lactotrophs: 4.3" "Cell type enriched" "Detected in single" 25 "Pituitary endocrine cells: 4.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Head and Neck Squamous Cell Carcinoma (TCGA): 2.2;Lung Squamous Cell Carcinoma (TCGA): 2.0;Testicular Germ Cell Tumor (TCGA): 1.8" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Neuroblastoma: 23.7" "Group enriched" "Detected in many" 4 "hypothalamus: 14.4;white matter: 5.0" "Region enriched" "Detected in single" 12 "hypothalamus: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 3 "Plasma membrane" "Nucleoplasm, Primary cilium, Primary cilium tip" "HPA049862: , HPA054678: " "unprognostic (3.88e-2)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" "unprognostic (7.53e-2)" GPR65 "hTDAG8, TDAG8" ENSG00000140030 "G protein-coupled receptor 65" Q8IYL9 14 88005135-88014811 "G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.9;lymphoid tissue: 9.1" "Cell type enhanced" "Detected in some" "cDC: 73.1;Innate lymphoid cells: 134.6;Kupffer cells: 168.1;Macrophages: 63.5;Mast cells: 547.0;monocytes: 70.3;Neutrophils: 241.0;NK-cells: 216.8;pDCs: 113.5;T-cells: 143.4" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 134.6;Mast cells: 547.0;Mononuclear phagocytes: 168.1;Neutrophils: 241.0;NK-cells: 216.8;T-cells: 143.4" "Group enriched" "Detected in some" 35 "central nervous system macrophage: 43.3;leukocyte: 99.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Leukemia: 3.6;lymphoma: 7.1" "Adrenal gland - Macrophages, Skeletal muscle - Macrophages, Testis - Early spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1571 "B-cells: 157080.6" "Not detected" "Not detected" "HPA072624, HPA077397" Enhanced Approved Nucleoli,Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 58: Mast cells - Allergic inflammatory responses" 1 Vesicles "Nucleoli, Cytosol" "HPA072624: , HPA077397: " "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (8.35e-2)" "unprognostic (3.04e-1)" "unprognostic (2.01e-1)" "unprognostic (2.93e-2)" "unprognostic (1.24e-1)" "unprognostic (3.28e-1)" "unprognostic (1.57e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (8.93e-4)" "unprognostic (2.96e-2)" "unprognostic (8.99e-2)" "unprognostic (4.73e-1)" "unprognostic (2.19e-1)" "unprognostic (8.79e-2)" "unprognostic (1.89e-1)" "unprognostic (2.33e-1)" "unprognostic (5.54e-2)" "unprognostic (1.87e-1)" "unprognostic (8.73e-3)" GPR75 WI-31133 ENSG00000119737 "G protein-coupled receptor 75" O95800 2 53852912-53859967 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8;retina: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 7.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA056032 Supported "Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Plasma membrane" "Vesicles, Primary cilium" "HPA056032: " "unprognostic (1.37e-1)" "unprognostic (4.79e-2)" "unprognostic (2.55e-2)" "unprognostic (5.93e-2)" "unprognostic (4.50e-1)" "unprognostic (7.27e-2)" "unprognostic (1.53e-1)" "unprognostic (8.54e-2)" "unprognostic (1.85e-2)" "unprognostic (2.02e-1)" "unprognostic (2.11e-2)" "unprognostic (1.53e-1)" "unprognostic (8.99e-2)" "unprognostic (2.64e-1)" GPR87 GPR95 ENSG00000138271 "G protein-coupled receptor 87" Q9BY21 3 151294086-151316820 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.1;skin 1: 37.4;vagina: 27.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 70.6;Cytotrophoblasts: 67.3;Epididymal basal cells: 378.7;Esophageal apical cells: 295.7;Esophageal basal cells: 74.4;Esophageal suprabasal cells: 139.4;Migrating cytotrophoblasts: 100.0;Ocular epithelial cells: 98.0;Suprabasal keratinocytes: 98.3;Syncytiotrophoblasts: 315.8;Urothelial cells: 127.3" "Group enriched" "Detected in many" 4 "Apical squamous epithelial cells: 295.7;Barrier epithelial cells: 127.3;Basal cells: 378.7;Suprabasal cells: 139.4;Trophoblast cells: 315.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 9.1" "Group enriched" "Detected in many" 5 "Bladder Urothelial Carcinoma (TCGA): 34.9;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 61.7;Head and Neck Squamous Cell Carcinoma (TCGA): 64.5;Lung Squamous Cell Carcinoma (TCGA): 58.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 70.8;head and neck cancer: 95.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA066313 Approved "Nucleoplasm,Lipid droplets,Mitochondria" No No "Cluster 81: Squamous epithelium - Keratinization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" "Lipid droplets, Mitochondria" Nucleoplasm "HPA066313: " "unprognostic (2.42e-1)" "unprognostic (1.54e-1)" "unprognostic (1.86e-1)" "unprognostic (8.63e-2)" "unprognostic (1.04e-2)" "unprognostic (5.06e-2)" "unprognostic (4.29e-3)" "unprognostic (1.37e-2)" "unprognostic (1.98e-2)" "unprognostic (9.04e-2)" "validated prognostic unfavorable (6.81e-6)" "validated prognostic unfavorable (2.69e-4)" "unprognostic (2.27e-1)" "unprognostic (3.21e-1)" "unprognostic (2.83e-3)" GPRASP1 "GASP, GASP1" ENSG00000198932 "G protein-coupled receptor associated sorting protein 1" Q5JY77 X 102651092-102659083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.9" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 13.8;Epididymal clear cells: 4.1;Loop of henle epithelial cells: 8.1;Medullary thymic epithelial cells: 4.8;Papillary tip epithelial cells: 4.4;Podocytes: 12.4;Proximal tubule cells: 11.1;Renal collecting duct intercalated cells: 13.0;Renal collecting duct principal cells: 9.9;Renal connecting tubule cells: 21.5" "Cell type enhanced" "Detected in some" "Ductal cells: 21.5;Renal nephron cells: 13.8" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 11.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.2" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2574 "Collecting ducts: 174754.0;Neurons: 447777.3;Oocytes: 149742.7" "Tissue enriched" "Detected in single" 604 "cerebral cortex: 60422.2" "HPA000161, HPA031061" Approved Supported Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 7 Cytosol "HPA000161: , HPA031061: " "potential prognostic favorable (9.79e-4)" "unprognostic (1.02e-3)" "unprognostic (3.18e-2)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (2.89e-1)" "unprognostic (2.13e-2)" "unprognostic (1.32e-1)" "unprognostic (5.19e-2)" "unprognostic (1.72e-3)" "unprognostic (3.25e-3)" "unprognostic (3.73e-2)" "unprognostic (2.62e-2)" "unprognostic (1.42e-2)" "unprognostic (4.50e-2)" "unprognostic (6.47e-2)" "unprognostic (3.19e-1)" "unprognostic (2.21e-1)" "potential prognostic favorable (3.81e-5)" "unprognostic (1.52e-1)" "unprognostic (1.57e-1)" "unprognostic (7.51e-2)" "unprognostic (9.39e-3)" "unprognostic (2.93e-1)" "unprognostic (2.12e-2)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (9.07e-4)" "unprognostic (8.61e-2)" GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46541736-46556658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.1;skin 1: 13.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 50.4;Colonocytes: 20.3;Enterocytes: 18.5;Goblet cells: 47.6;Late spermatids: 29.2;Mucous neck cells: 16.5;Paneth cells: 27.1" "Cell type enhanced" "Detected in many" "Alveolar cells: 50.4;Goblet cells: 47.6;Secretory gland support: 27.1;Spermatogenic cell types: 29.2" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 6.0;lower rhombic lip: 5.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 6.0;prostate cancer: 8.1" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 1, Pancreas - Ductal cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 109 "Collecting ducts: 10945.3" "Tissue enriched" "Detected in single" 35082 "intestine: 3508150.6" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 2: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 70: Intestinal goblet cells - Mucin production" 7 "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: , HPA070760: " "unprognostic (4.92e-3)" "unprognostic (3.13e-3)" "unprognostic (9.93e-2)" "unprognostic (1.92e-1)" "unprognostic (1.46e-1)" "unprognostic (1.92e-1)" "potential prognostic favorable (5.44e-4)" "unprognostic (3.39e-2)" "unprognostic (2.69e-1)" "unprognostic (2.39e-3)" "unprognostic (1.23e-3)" "unprognostic (5.31e-2)" "unprognostic (8.80e-2)" "unprognostic (3.84e-1)" "unprognostic (1.08e-1)" "unprognostic (8.58e-2)" "unprognostic (1.36e-3)" "unprognostic (1.42e-2)" "unprognostic (3.75e-1)" "unprognostic (3.20e-1)" "unprognostic (5.04e-3)" "unprognostic (3.74e-2)" "unprognostic (3.64e-1)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (8.29e-4)" GPRIN3 "FLJ42625, GRIN3" ENSG00000185477 "GPRIN family member 3" Q6ZVF9 4 89236383-89307800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.9" "Cell type enhanced" "Detected in many" "cDC: 186.5;Distal convoluted tubule cells: 185.5;Lactotrophs: 181.3;Macrophages: 207.2;Microglia: 207.8;NK-cells: 263.8;Renal collecting duct intercalated cells: 183.4;Somatotrophs: 225.1;T-cells: 337.7;Thyrotrophs: 218.6" "Cell type enhanced" "Detected in many" "NK-cells: 263.8;T-cells: 337.7" "Cell type enhanced" "Detected in all" "leukocyte: 351.6" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 13.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Myeloma: 28.5" "Adipose visceral - T-cells, Prostate - T-cells, Skeletal muscle - Endothelial cells" "Region enhanced" "Detected in many" "basal ganglia: 16.3" "Cell type enhanced" "Detected in many" "Glomeruli: 2063697.6" "Tissue enhanced" "Detected in many" "bone marrow: 120300645.3;kidney: 121461858.5" "HPA043148, HPA057666, HPA059092" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 Nucleoli Nucleoplasm "HPA043148: , HPA057666: , HPA059092: " "unprognostic (1.78e-1)" "unprognostic (4.09e-2)" "unprognostic (2.89e-1)" "unprognostic (2.24e-2)" "unprognostic (2.66e-2)" "unprognostic (4.98e-2)" "unprognostic (3.50e-1)" "unprognostic (3.76e-1)" "potential prognostic favorable (9.91e-6)" "unprognostic (2.01e-2)" "unprognostic (4.96e-1)" "unprognostic (1.59e-1)" "unprognostic (4.14e-2)" "unprognostic (7.09e-2)" "unprognostic (5.24e-2)" "unprognostic (1.42e-2)" "unprognostic (4.08e-3)" "unprognostic (9.43e-2)" "unprognostic (6.28e-2)" "unprognostic (2.84e-1)" "unprognostic (2.77e-2)" "unprognostic (1.08e-1)" "unprognostic (1.92e-1)" "unprognostic (1.50e-1)" GPT2 ALT2 ENSG00000166123 "Glutamic--pyruvic transaminase 2" Q8TD30 16 46884362-46931289 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 252.0;skeletal muscle: 165.4;tongue: 172.2" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 761.9" "Cell type enriched" "Detected in many" 4 "Apical squamous epithelial cells: 761.9" "Cell type enhanced" "Detected in all" "astrocyte: 128.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 1.3;naive B-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 6829943.7;Proximal tubules: 9841793.7;Skeletal myofibers: 5827536.1" "Tissue enhanced" "Detected in many" "pancreas: 4221823.1;skeletal muscle: 4354185.4" HPA051514 Approved Approved Mitochondria No No "Cluster 32: Basophils - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 84: Apical squamous epithelium - Cornification" 5 Mitochondria "HPA051514: " "unprognostic (6.18e-2)" "unprognostic (1.18e-2)" "unprognostic (4.55e-2)" "unprognostic (1.70e-1)" "unprognostic (2.62e-1)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (3.82e-2)" "unprognostic (4.71e-2)" "unprognostic (2.53e-1)" "unprognostic (2.81e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (6.39e-4)" "unprognostic (1.06e-3)" "unprognostic (1.30e-1)" "unprognostic (1.67e-1)" "unprognostic (3.48e-1)" "unprognostic (7.43e-3)" "unprognostic (8.84e-3)" "unprognostic (5.08e-1)" "unprognostic (3.00e-2)" "unprognostic (2.64e-1)" "unprognostic (1.53e-1)" "unprognostic (2.49e-2)" "unprognostic (1.95e-1)" "unprognostic (1.91e-1)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "unprognostic (1.35e-3)" "unprognostic (2.66e-2)" GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 53.4;Cytotrophoblasts: 58.0;Decidual stromal cells: 111.8;Endometrial stromal cells: 52.8;Epididymal principal cells: 51.5;Extravillous trophoblasts: 310.2;Fibroblasts: 76.5;Hepatic stellate cells: 58.1;Melanocytes: 50.4;Migrating cytotrophoblasts: 94.4;Respiratory deuterosomal cells: 64.3" "Cell type enhanced" "Detected in many" "Stromal cells: 111.8;Trophoblast cells: 310.2" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 12.5;fibroblast: 29.5;pericyte: 12.1;vascular associated smooth muscle cell: 9.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 13.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1409872.9;Pancreatic islets: 1614599.3" "Group enriched" "Detected in many" "bone marrow: 1029573.3;salivary gland: 406195.6" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 8: Immune cells - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 180 "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: " "unprognostic (5.47e-2)" "unprognostic (4.97e-2)" "unprognostic (3.53e-1)" "unprognostic (1.57e-2)" "unprognostic (5.65e-2)" "unprognostic (3.13e-2)" "unprognostic (3.93e-2)" "potential prognostic unfavorable (6.08e-7)" "unprognostic (1.85e-3)" "unprognostic (4.61e-2)" "unprognostic (2.28e-3)" "potential prognostic unfavorable (7.19e-4)" "unprognostic (1.46e-2)" "unprognostic (6.56e-3)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (1.03e-5)" "unprognostic (3.32e-3)" "unprognostic (2.68e-1)" "unprognostic (4.59e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.84e-5)" "unprognostic (1.45e-2)" "unprognostic (3.81e-3)" "unprognostic (1.88e-1)" "unprognostic (4.12e-2)" "unprognostic (5.09e-1)" "unprognostic (9.88e-3)" "unprognostic (5.56e-3)" "unprognostic (1.53e-2)" "unprognostic (1.38e-2)" "unprognostic (2.33e-1)" GRAP2 "GADS, GRBLG, GrbX, Grf40, Mona" ENSG00000100351 "GRB2 related adaptor protein 2" O75791 22 39901084-39973721 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "lymphoid tissue: 171.9" "Cell type enriched" "Detected in many" 4 "Platelets: 1719.7" "Cell type enriched" "Detected in many" 4 "Platelets: 1719.7" "Cell type enriched" "Detected in many" 130 "leukocyte: 471.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 51.5;MAIT T-cell: 38.3;memory CD4 T-cell: 37.6;memory CD8 T-cell: 56.2;naive CD4 T-cell: 31.3;naive CD8 T-cell: 58.4;T-reg: 35.1" "Lineage enriched" "Detected in many" 9 "T-cells: 58.4" "Cancer enriched" "Detected in some" 6 "Leukemia: 29.3" "Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Kidney - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" "Fallopian tube cells: 65361789.0" "Group enriched" "Detected in many" "intestine: 10908570.8;lymphoid tissue: 6308545.5" "HPA005788, CAB022073" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 330000 "Cluster 11: T-cells - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 58: Mast cells - Allergic inflammatory responses" 74 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022073: , HPA005788: " "unprognostic (1.06e-3)" "unprognostic (6.54e-2)" "unprognostic (1.53e-1)" "unprognostic (2.14e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (4.20e-2)" "unprognostic (3.44e-2)" "unprognostic (1.53e-2)" "potential prognostic favorable (6.13e-5)" "unprognostic (4.08e-2)" "unprognostic (1.84e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (8.90e-4)" "unprognostic (2.51e-2)" "unprognostic (1.84e-1)" "unprognostic (1.34e-1)" "unprognostic (9.46e-3)" "unprognostic (4.44e-2)" "unprognostic (1.19e-1)" "unprognostic (3.39e-2)" GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.0;kidney: 59.1" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 384.1;Esophageal basal cells: 142.9;Esophageal suprabasal cells: 174.9;Ocular epithelial cells: 121.6;Paneth cells: 143.1;Prostatic club cells: 121.3;Prostatic hillock cells: 132.1;Syncytiotrophoblasts: 152.5" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 384.1;Suprabasal cells: 174.9" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 10.0;upper rhombic lip: 5.7" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 9 "cerebellum: 11.6;choroid plexus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 130.5;Esophageal cancer: 160.3" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Pituitary gland - Somatotropes" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 2622627.6" "Tissue enhanced" "Detected in some" "intestine: 985992.9" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 41 "Plasma membrane, Cytosol" "CAB005226: , CAB073538: , HPA057084: " "unprognostic (6.98e-2)" "unprognostic (6.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.82e-1)" "unprognostic (5.01e-2)" "unprognostic (7.86e-2)" "unprognostic (3.53e-2)" "unprognostic (8.56e-2)" "potential prognostic favorable (2.10e-4)" "unprognostic (1.49e-2)" "unprognostic (2.98e-1)" "unprognostic (6.68e-2)" "unprognostic (5.05e-3)" "unprognostic (3.43e-1)" "unprognostic (8.08e-2)" "unprognostic (1.34e-1)" "unprognostic (2.28e-1)" "unprognostic (1.24e-3)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (1.43e-2)" "unprognostic (2.93e-1)" "unprognostic (6.09e-3)" "unprognostic (7.17e-3)" "unprognostic (2.01e-1)" "unprognostic (2.05e-2)" "unprognostic (4.27e-2)" "unprognostic (3.55e-3)" "unprognostic (4.74e-3)" GRHL3 "SOM, TFCP2L4" ENSG00000158055 "Grainyhead like transcription factor 3" Q8TE85 1 24199558-24364482 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.2;skin 1: 49.4;vagina: 42.5" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 77.8;Esophageal apical cells: 537.9;Esophageal basal cells: 64.0;Esophageal suprabasal cells: 251.2;Ocular epithelial cells: 193.1;Suprabasal keratinocytes: 215.5;Urothelial cells: 304.3" "Group enriched" "Detected in many" 4 "Apical squamous epithelial cells: 537.9;Barrier epithelial cells: 304.3;Suprabasal cells: 251.2" "Group enriched" "Detected in some" 4 "astrocyte: 4.2;central nervous system macrophage: 1.9" "Group enriched" "Detected in many" 9 "Bladder Urothelial Carcinoma (TCGA): 54.4;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 30.6;Head and Neck Squamous Cell Carcinoma (TCGA): 34.8;Lung Squamous Cell Carcinoma (TCGA): 19.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 37.7;testis cancer: 30.1" "Adipose visceral - Mesothelial cells, Prostate - Urothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA059960 Enhanced Supported "Nucleoplasm,Actin filaments,Primary cilium,Cytosol" NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 8 Nucleoplasm "Actin filaments, Primary cilium, Cytosol" "HPA059960: " "potential prognostic favorable (9.54e-5)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (2.27e-1)" "unprognostic (9.36e-2)" "unprognostic (2.33e-2)" "unprognostic (2.15e-2)" "unprognostic (1.04e-3)" "unprognostic (2.82e-2)" "unprognostic (2.69e-2)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (2.46e-2)" "unprognostic (1.12e-2)" "unprognostic (1.14e-1)" "unprognostic (2.91e-1)" "unprognostic (1.18e-3)" "unprognostic (9.68e-2)" "unprognostic (5.84e-2)" "unprognostic (1.26e-2)" "unprognostic (1.47e-1)" "unprognostic (2.18e-1)" "unprognostic (1.66e-1)" "unprognostic (5.60e-3)" "unprognostic (6.10e-2)" GRID2IP ENSG00000215045 "Grid2 interacting protein" A4D2P6 7 6496778-6551461 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.4" "Cell type enhanced" "Detected in many" "Epicardial cells: 20.5;Gonadotrophs: 22.0;Retinal ganglion cells: 19.3;Tuft cells: 46.1" "Cell type enhanced" "Detected in many" "Secretory gland support: 46.1" "Cell type enriched" "Detected in many" 5 "thalamic excitatory: 60.1" "Low cancer specificity" "Detected in single" "Region enhanced" "Detected in all" "thalamus: 72.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Leukemia: 2.5" "Adrenal gland - Adrenal cortex cells" "Group enriched" "Detected in many" 5 "cerebellum: 22.4;thalamus: 7.2" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 657 "Skeletal myofibers: 65655.5" "Not detected" "Not detected" HPA045381 Approved "Plasma membrane" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 1 "Plasma membrane" "HPA045381: " "unprognostic (2.44e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" GRIK5 "GluK5, GRIK2, KA2" ENSG00000105737 "Glutamate ionotropic receptor kainate type subunit 5" Q16478 19 41998321-42070206 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.5;testis: 31.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 66.0;Brain inhibitory neurons: 59.0;Choroid plexus epithelial cells: 49.4;Distal convoluted tubule cells: 44.5;Early primary spermatocytes: 43.6;Gonadotrophs: 49.6;Oligodendrocyte progenitor cells: 46.9;Other brain neurons: 50.1;Pituicytes/FSCs: 41.1;Retinal amacrine cells: 55.2;Retinal bipolar cells: 65.0;Retinal ganglion cells: 42.5;Retinal horizontal cells: 52.1;Rod photoreceptor cells: 73.9;Thyrotrophs: 52.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 53.2;Ciliated cells: 49.4;Glial cells: 46.9;Neuronal cells: 73.9;Pituitary endocrine cells: 52.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 35.3;Kidney Chromophobe (TCGA): 10.6;Ovary Serous Cystadenocarcinoma (TCGA): 11.9;Thyroid Carcinoma (TCGA): 11.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 9.9;Neuroblastoma: 19.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Lung - Smooth muscle cells, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2560 "Fallopian tube cells: 403759.7;Microglia and Neuropil: 137765.8;Oocytes: 226622.8" "Tissue enriched" "Detected in single" 1582 "cerebral cortex: 158198.7" HPA074001 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 65: Brain - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Plasma membrane" Nucleoplasm "HPA074001: " "unprognostic (9.31e-2)" "unprognostic (1.41e-1)" "unprognostic (1.94e-2)" "unprognostic (1.59e-1)" "unprognostic (5.06e-3)" "unprognostic (1.66e-1)" "unprognostic (8.59e-2)" "unprognostic (1.32e-3)" "unprognostic (8.04e-3)" "potential prognostic favorable (4.37e-4)" "unprognostic (1.06e-1)" "unprognostic (6.18e-2)" "unprognostic (1.44e-2)" "unprognostic (1.12e-1)" "unprognostic (3.87e-2)" "unprognostic (1.46e-1)" GRIN2B "GluN2B, NMDAR2B" ENSG00000273079 "Glutamate ionotropic receptor NMDA type subunit 2B" Q13224 12 13437942-13982002 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "brain: 6.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 677.9;Brain inhibitory neurons: 895.2;Oligodendrocyte progenitor cells: 253.8;Other brain neurons: 372.0;Pituitary stem cells: 97.1;Retinal amacrine cells: 169.6;Retinal ganglion cells: 104.3;Tuft cells: 184.5" "Cell type enhanced" "Detected in many" "Glial cells: 253.8;Neuronal cells: 895.2;Secretory gland support: 184.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 1.1;Rectum Adenocarcinoma (TCGA): 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 1.5" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 61904 "Astrocytes and Neuropil: 4245949.7;Microglia and Neuropil: 11112305.5;Neurons: 3212934.0" "Tissue enriched" "Detected in some" "cerebral cortex: 10569834.2" "HPA052160, HPA069762" Approved Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip,Primary cilium transition zone,Basal body" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 35: Neurons - Synaptic function & neurogenesis" 26 "Plasma membrane" "Nucleoplasm, Primary cilium, Primary cilium tip, Primary cilium transition zone, Basal body" "HPA052160: , HPA069762: " "unprognostic (1.63e-1)" "unprognostic (5.01e-2)" "unprognostic (9.12e-2)" "unprognostic (5.18e-2)" "unprognostic (1.15e-1)" GRPR "BB2, BB2R, BRS2" ENSG00000126010 "Gastrin releasing peptide receptor" P30550 X 16123565-16153518 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "pancreas: 19.1" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 3.1;Breast hormone-responsive cells: 3.0;Cone photoreceptor cells: 2.1;Neuroendocrine cells: 3.6;Oocytes: 13.8;Pancreatic acinar cells: 10.8;Retinal pigment epithelial cells: 4.3;Sertoli cells: 2.5;Thyrotrophs: 3.4" "Cell type enhanced" "Detected in some" "Acinar cells: 10.8;Oocytes: 13.8" "Group enriched" "Detected in some" 7 "CGE interneuron: 19.2;LAMP5-LHX6 and Chandelier: 19.3;mammillary body: 7.0" "Cancer enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 11.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 12.1;Rhabdoid: 7.9" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA069604 Supported "Plasma membrane" NA NA "Cluster 8: Pancreas - Proteolysis" "Cluster 14: Neurons - Synaptic function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 109: Neurons - Neuronal signaling" "Plasma membrane" "HPA069604: " "unprognostic (8.22e-2)" "unprognostic (4.73e-1)" "unprognostic (1.45e-1)" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (4.27e-1)" "unprognostic (8.23e-2)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" "unprognostic (2.40e-1)" GRWD1 "GRWD, RRB1, WDR28" ENSG00000105447 "Glutamate rich WD repeat containing 1" Q9BQ67 19 48445841-48457022 "Essential proteins, Predicted intracellular proteins" "DNA replication" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 59.7;Migrating cytotrophoblasts: 54.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 4136805.9" "Low tissue specificity" "Detected in many" "HPA042643, HPA055680" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 47 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA042643: , HPA055680: " "unprognostic (1.24e-1)" "unprognostic (8.75e-2)" "unprognostic (2.66e-2)" "unprognostic (3.66e-3)" "unprognostic (7.05e-2)" "unprognostic (8.51e-2)" "unprognostic (2.45e-1)" "unprognostic (2.20e-1)" "unprognostic (1.93e-2)" "unprognostic (3.04e-2)" "potential prognostic favorable (1.07e-6)" "unprognostic (2.00e-2)" "unprognostic (2.85e-1)" "unprognostic (6.20e-3)" "potential prognostic unfavorable (4.67e-4)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (6.74e-2)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (6.47e-2)" "unprognostic (1.49e-1)" "unprognostic (6.21e-2)" "unprognostic (1.96e-1)" "unprognostic (1.63e-2)" "unprognostic (9.15e-2)" "unprognostic (4.66e-2)" "unprognostic (8.59e-3)" "unprognostic (1.86e-1)" "unprognostic (2.90e-1)" "unprognostic (9.88e-2)" "unprognostic (8.49e-2)" GSK3B ENSG00000082701 "Glycogen synthase kinase 3 beta" P49841 3 119821321-120094994 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Biological rhythms, Carbohydrate metabolism, Differentiation, Glycogen metabolism, Neurogenesis, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Signal transduction inhibitor, Transferase" "Alzheimer disease, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 760.9" "Cell type enhanced" "Detected in all" "Neutrophils: 760.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia and Neuropil: 7929377.9;Neurons: 11994471.8" "Tissue enriched" "Detected in many" "cerebral cortex: 19951861.1" "HPA006495, CAB016263, HPA028017, CAB080481, CAB080483, CAB080485, CAB080488, CAB080489" Approved Enhanced Nucleoplasm No No "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 24: Neutrophils - Innate immunity signal integration" 251 Nucleoplasm "CAB016263: , CAB080481: , CAB080483: , CAB080485: , CAB080488: , CAB080489: , HPA006495: , HPA028017: " "unprognostic (3.14e-1)" "unprognostic (8.88e-3)" "unprognostic (1.63e-1)" "unprognostic (4.60e-3)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "unprognostic (1.28e-1)" "unprognostic (4.12e-3)" "unprognostic (8.81e-2)" "unprognostic (4.59e-3)" "potential prognostic favorable (1.09e-4)" "unprognostic (3.34e-1)" "unprognostic (1.31e-1)" "unprognostic (5.99e-3)" "unprognostic (2.60e-1)" "unprognostic (2.98e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-1)" "unprognostic (4.50e-2)" "unprognostic (1.35e-3)" "unprognostic (1.57e-3)" "unprognostic (1.01e-2)" "unprognostic (1.02e-2)" "unprognostic (4.47e-2)" "unprognostic (8.79e-2)" "unprognostic (6.96e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-1)" "unprognostic (3.08e-1)" "unprognostic (2.07e-1)" "unprognostic (2.51e-1)" GSKIP C14orf129 ENSG00000100744 "GSK3B interacting protein" Q9P0R6 14 96363452-96387288 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 440.7;Esophageal apical cells: 336.0;Late spermatids: 419.0;Oocytes: 165.8;Syncytiotrophoblasts: 151.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 336.0;Spermatogenic cell types: 440.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA043054, HPA046782" Approved Approved "Nucleoli,Golgi apparatus,Vesicles" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 10 "Golgi apparatus, Vesicles" Nucleoli "HPA043054: , HPA046782: " "unprognostic (6.79e-2)" "unprognostic (7.37e-2)" "unprognostic (5.50e-2)" "unprognostic (2.60e-3)" "unprognostic (1.47e-1)" "unprognostic (1.30e-1)" "unprognostic (3.12e-2)" "unprognostic (6.40e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (1.91e-5)" "unprognostic (3.55e-1)" "unprognostic (3.47e-1)" "unprognostic (1.40e-2)" "unprognostic (2.43e-2)" "unprognostic (2.86e-2)" "unprognostic (3.54e-1)" "unprognostic (2.50e-1)" "unprognostic (4.78e-2)" "unprognostic (2.13e-2)" "unprognostic (1.08e-2)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (1.20e-1)" "unprognostic (1.28e-3)" "unprognostic (1.38e-1)" "unprognostic (9.83e-2)" "unprognostic (2.78e-1)" "unprognostic (1.20e-2)" "unprognostic (2.74e-1)" GSPT1 "eRF3a, ETF3A, GST1" ENSG00000103342 "G1 to S phase transition 1" P15170 16 11868128-11916082 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA052488, HPA074588" Approved Approved Vesicles,Cytosol NA NA 240000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 170 Cytosol Vesicles "HPA052488: , HPA074588: " "unprognostic (7.02e-3)" "unprognostic (4.00e-3)" "unprognostic (2.67e-1)" "unprognostic (2.18e-2)" "unprognostic (4.99e-2)" "unprognostic (1.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.77e-1)" "unprognostic (5.74e-3)" "unprognostic (5.93e-3)" "potential prognostic favorable (1.07e-5)" "unprognostic (3.66e-1)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (6.38e-5)" "unprognostic (1.29e-3)" "unprognostic (3.54e-2)" "unprognostic (1.50e-2)" "unprognostic (1.28e-1)" "unprognostic (4.32e-1)" "unprognostic (1.12e-1)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (5.28e-5)" "unprognostic (8.51e-3)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.35e-2)" "unprognostic (2.22e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-1)" "unprognostic (2.56e-3)" "unprognostic (3.39e-3)" GSPT2 "eRF3b, FLJ10441" ENSG00000189369 "G1 to S phase transition 2" Q8IYD1 X 51743442-51746232 "Predicted intracellular proteins" "Cell cycle, Nonsense-mediated mRNA decay, Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 87.3;Late primary spermatocytes: 64.8;Late spermatids: 328.7;Müller glia: 52.9" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 328.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "testis cancer: 35.8" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 2116573.9" "Low tissue specificity" "Detected in many" "HPA044769, HPA074588" Approved Enhanced Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 30 Cytosol "HPA044769: , HPA074588: " "unprognostic (3.99e-2)" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (4.37e-2)" "unprognostic (2.64e-1)" "unprognostic (2.64e-3)" "unprognostic (2.32e-1)" "unprognostic (9.53e-2)" "unprognostic (1.40e-2)" "unprognostic (7.22e-2)" "potential prognostic favorable (4.18e-4)" "unprognostic (1.32e-2)" "unprognostic (5.74e-2)" "unprognostic (2.59e-2)" "unprognostic (2.98e-2)" "unprognostic (4.41e-1)" "unprognostic (1.96e-2)" "unprognostic (2.04e-1)" "unprognostic (3.31e-2)" "unprognostic (4.21e-1)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (4.76e-4)" "unprognostic (2.15e-1)" "unprognostic (6.27e-2)" "unprognostic (1.95e-1)" "unprognostic (2.67e-1)" "unprognostic (1.86e-2)" "unprognostic (5.36e-3)" "unprognostic (1.78e-1)" "unprognostic (1.05e-3)" GSR ENSG00000104687 "Glutathione-disulfide reductase" P00390 8 30678066-30727846 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 199.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 32.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland basal cells, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA001538, CAB008632, HPA064806" Approved Supported "Endoplasmic reticulum,Cytosol" NA NA 32000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 48: Neutrophils - Phagocytosis & degranulation" Cytosol "Endoplasmic reticulum" "CAB008632: , HPA001538: , HPA064806: " "potential prognostic favorable (7.98e-4)" "unprognostic (7.89e-2)" "unprognostic (3.73e-1)" "unprognostic (1.39e-3)" "potential prognostic favorable (2.04e-4)" "unprognostic (1.15e-1)" "unprognostic (2.06e-1)" "unprognostic (2.40e-2)" "unprognostic (1.75e-1)" "unprognostic (1.95e-3)" "potential prognostic favorable (1.31e-5)" "unprognostic (7.44e-2)" "unprognostic (7.17e-3)" "potential prognostic unfavorable (3.93e-6)" "unprognostic (8.37e-2)" "unprognostic (1.48e-2)" "unprognostic (2.51e-2)" "unprognostic (1.38e-1)" "unprognostic (2.60e-1)" "unprognostic (7.21e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-2)" "unprognostic (2.93e-2)" "unprognostic (7.79e-2)" "unprognostic (1.71e-2)" "unprognostic (7.69e-2)" "unprognostic (4.00e-2)" "unprognostic (2.36e-2)" "unprognostic (2.42e-1)" "unprognostic (2.48e-2)" "unprognostic (5.35e-2)" GSS ENSG00000100983 "Glutathione synthetase" P48637 20 34928432-34956027 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glutathione biosynthesis" Ligase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 151.7;Late spermatids: 320.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 320.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA054508, HPA059315" Enhanced Supported Nucleoplasm NA NA 20000000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 Nucleoplasm "HPA054508: , HPA059315: " "unprognostic (5.50e-2)" "unprognostic (2.64e-1)" "unprognostic (3.63e-2)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (9.71e-2)" "unprognostic (1.31e-2)" "unprognostic (2.83e-1)" "unprognostic (1.18e-1)" "unprognostic (6.07e-2)" "unprognostic (1.71e-2)" "unprognostic (3.83e-3)" "potential prognostic favorable (1.04e-7)" "potential prognostic unfavorable (8.01e-5)" "unprognostic (1.17e-3)" "unprognostic (1.55e-3)" "unprognostic (4.86e-2)" "unprognostic (8.46e-2)" "unprognostic (2.04e-1)" "unprognostic (2.43e-1)" "unprognostic (2.23e-1)" "unprognostic (1.08e-2)" "unprognostic (2.85e-1)" "unprognostic (8.52e-2)" "unprognostic (1.63e-2)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (1.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.13e-2)" "unprognostic (1.28e-2)" GSTA1 ENSG00000243955 "Glutathione S-transferase alpha 1" P08263 6 52791371-52803860 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" "Isomerase, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 635.7;intestine: 635.6;kidney: 880.2;liver: 2438.9" "Cell type enhanced" "Detected in many" "Cholangiocytes: 368.9;Conjunctival goblet cells: 1159.2;Enteric transient amplifying cells: 695.6;Enterocytes: 3964.0;Granulosa cells: 579.1;Hepatocytes: 1378.2;Parietal cells: 914.0;Respiratory ciliated cells: 864.5;Respiratory secretory cells: 466.3" "Cell type enhanced" "Detected in many" "Enterocytes: 3964.0;Gastric glandular cells: 914.0;Goblet cells: 1159.2;Hepatocytes: 1378.2" "Cell type enriched" "Detected in single" 4 "cerebellar inhibitory: 1.8" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 316.4;Liver Hepatocellular Carcinoma (TCGA): 712.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "liver cancer: 69.2" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Leydig cells" "Group enriched" "Detected in many" "Glomeruli: 1047747289.9;Hepatocytes: 767277198.1" "Group enriched" "Detected in many" "kidney: 1005889323.0;liver: 727816428.2;pancreas: 459941788.1" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA 6000000 "Cluster 76: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 4 Cytosol "HPA004342: , HPA048934: , HPA053817: " "unprognostic (2.13e-1)" "unprognostic (9.07e-3)" "unprognostic (3.42e-1)" "unprognostic (2.56e-2)" "unprognostic (2.47e-1)" "unprognostic (9.59e-2)" "unprognostic (4.28e-3)" "unprognostic (3.14e-3)" "potential prognostic favorable (5.91e-4)" "unprognostic (1.64e-2)" "unprognostic (5.41e-2)" "unprognostic (4.29e-3)" "unprognostic (1.91e-3)" "unprognostic (8.32e-2)" "unprognostic (1.47e-2)" "unprognostic (3.47e-2)" "unprognostic (2.39e-2)" "unprognostic (3.15e-1)" "unprognostic (7.47e-2)" "unprognostic (1.22e-1)" "unprognostic (5.37e-2)" "unprognostic (4.56e-1)" "unprognostic (1.60e-2)" "unprognostic (3.81e-2)" "unprognostic (6.79e-2)" "unprognostic (4.22e-2)" GSTA2 GST2 ENSG00000244067 "Glutathione S-transferase alpha 2" P09210 6 52750087-52763475 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 649.1;liver: 1924.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 174.4;Enteric transient amplifying cells: 86.6;Enterocytes: 303.5;Hepatocytes: 163.7;Pancreatic acinar cells: 195.5;Respiratory ciliated cells: 711.2" "Cell type enhanced" "Detected in many" "Acinar cells: 195.5;Ciliated cells: 711.2;Ductal cells: 174.4;Enterocytes: 303.5;Hepatocytes: 163.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 19 "Kidney Renal Clear Cell Carcinoma (TCGA): 169.5;Liver Hepatocellular Carcinoma (TCGA): 244.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "liver cancer: 21.5" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Sertoli cells" "Group enriched" "Detected in many" "Glomeruli: 328877616.5;Hepatocytes: 98080173.0;Proximal tubules: 359010388.7" "Group enriched" "Detected in many" "kidney: 153627650.2;liver: 197464590.2;pancreas: 134279358.9" "HPA004342, HPA048934, HPA053817" Supported Supported Cytosol NA NA "Cluster 16: Liver & Kidney - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 107: Ciliated cells - Cilia assembly & function" 8 Cytosol "HPA004342: , HPA048934: , HPA053817: " "unprognostic (4.67e-2)" "unprognostic (1.59e-1)" "validated prognostic favorable (9.08e-4)" "validated prognostic favorable (1.97e-4)" "unprognostic (1.14e-1)" "unprognostic (1.82e-1)" "unprognostic (9.90e-2)" "unprognostic (9.11e-3)" "unprognostic (6.75e-2)" "unprognostic (8.10e-2)" "unprognostic (1.55e-1)" "unprognostic (1.58e-1)" "unprognostic (9.71e-2)" "unprognostic (2.20e-1)" "unprognostic (8.26e-3)" "unprognostic (1.82e-1)" GSTA3 ENSG00000174156 "Glutathione S-transferase alpha 3" Q16772 6 52896639-52909698 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 61.8;fallopian tube: 61.4;placenta: 21.3;skin 1: 24.5" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 53.9;Cytotrophoblasts: 324.9;Endometrial ciliated cells: 63.9;Epididymal efferent duct ciliated cells: 170.8;Fallopian tube ciliated cells: 239.3;Respiratory ciliated cells: 76.4;Syncytiotrophoblasts: 844.4" "Group enriched" "Detected in some" 10 "Ciliated cells: 239.3;Trophoblast cells: 844.4" "Group enriched" "Detected in some" 10 "choroid plexus epithelial cell: 5.8;ependymal cell: 3.3" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 3.2;Uterine Corpus Endometrial Carcinoma (TCGA): 3.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 1.1;testis cancer: 1.3" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland basal cells" "Group enriched" "Detected in some" "Fallopian tube cells: 3167575.9;Glomeruli: 4133117.3;Hepatocytes: 5308368.5;Proximal tubules: 2809995.4" "Tissue enriched" "Detected in single" 17687 "fallopian tube: 1768730.5" "HPA004342, HPA048934, HPA053817" Approved Supported Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 1 Cytosol "HPA004342: , HPA048934: , HPA053817: " "unprognostic (4.24e-2)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (7.72e-2)" "unprognostic (6.75e-2)" "unprognostic (2.01e-1)" GSTA5 ENSG00000182793 "Glutathione S-transferase alpha 5" Q7RTV2 6 52831655-52840843 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Conjunctival goblet cells: 2.9" "Cell type enhanced" "Detected in single" "Goblet cells: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004342, HPA048934, HPA053817" Uncertain Approved Cytosol NA NA "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 Cytosol "HPA004342: , HPA048934: , HPA053817: " GSTK1 GST13 ENSG00000197448 "Glutathione S-transferase kappa 1" Q9Y2Q3 7 143244093-143270854 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 663.5;Enterocytes: 588.0;Late spermatids: 1578.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1578.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubules: 235457414.7" "Tissue enhanced" "Detected in all" "liver: 149064546.2" "HPA006311, HPA022904" Supported Supported Peroxisomes NA NA 140000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 36: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 8 Peroxisomes "HPA006311: , HPA022904: " "unprognostic (4.51e-3)" "unprognostic (1.61e-3)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "unprognostic (2.65e-2)" "unprognostic (3.81e-1)" "unprognostic (2.64e-3)" "unprognostic (3.30e-3)" "unprognostic (3.49e-2)" "unprognostic (8.79e-2)" "potential prognostic favorable (3.26e-4)" "unprognostic (9.24e-2)" "potential prognostic favorable (1.21e-6)" "unprognostic (2.04e-1)" "unprognostic (9.83e-3)" "unprognostic (1.18e-2)" "unprognostic (2.00e-1)" "unprognostic (2.28e-1)" "unprognostic (8.09e-3)" "unprognostic (2.63e-3)" "unprognostic (9.64e-2)" "unprognostic (4.82e-3)" "unprognostic (9.40e-3)" "unprognostic (1.69e-1)" "unprognostic (1.94e-1)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.61e-2)" "unprognostic (8.32e-2)" "unprognostic (2.33e-2)" "unprognostic (1.80e-2)" GSTM1 "GST1, H-B, MU" ENSG00000134184 "Glutathione S-transferase mu 1" P09488 1 109687814-109709039 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 569.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.5;Hematopoietic stem cells: 3.9;Hepatic stellate cells: 6.5;Kupffer cells: 7.2;Medullary thymic epithelial cells: 4.8;Peritubular myoid cells: 4.1;Platelets: 4.2;Suprabasal keratinocytes: 5.6;Urothelial cells: 13.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 13.0;Basal cells: 7.5" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.4;choroid plexus epithelial cell: 1.0" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 484.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 15310 "intestine: 1530964.1" "CAB022669, CAB047357, HPA048652, HPA055972, HPA055973" Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 50: Lymphoma - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 1 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip, Primary cilium transition zone" "CAB022669: , CAB047357: , HPA048652: , HPA055972: , HPA055973: " "unprognostic (1.13e-2)" "unprognostic (3.23e-2)" "unprognostic (2.37e-1)" "unprognostic (5.80e-2)" "unprognostic (1.39e-2)" "unprognostic (2.19e-1)" "unprognostic (8.50e-2)" "unprognostic (2.13e-1)" "unprognostic (1.58e-1)" "unprognostic (2.12e-1)" "unprognostic (1.30e-2)" "unprognostic (2.16e-1)" "unprognostic (2.13e-1)" "unprognostic (3.03e-2)" "unprognostic (1.47e-2)" "unprognostic (3.45e-1)" "unprognostic (1.14e-1)" "unprognostic (6.85e-2)" "unprognostic (1.30e-1)" "unprognostic (5.08e-2)" "unprognostic (1.14e-1)" "unprognostic (2.66e-1)" "unprognostic (1.38e-2)" "unprognostic (3.76e-1)" "unprognostic (3.42e-1)" "unprognostic (4.25e-2)" "unprognostic (4.27e-1)" "unprognostic (2.19e-1)" "unprognostic (9.72e-2)" "unprognostic (2.77e-1)" "unprognostic (1.30e-1)" GSTM2 GST4 ENSG00000213366 "Glutathione S-transferase mu 2" P28161 1 109668022-109709551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 36.9;Fibro-adipogenic progenitors: 48.7;Hematopoietic stem cells: 75.2;Mast cells: 64.3;Medullary thymic epithelial cells: 40.8;Pituitary stem cells: 38.6" "Cell type enhanced" "Detected in many" "Mast cells: 64.3;Stem cells: 75.2" "Cell type enhanced" "Detected in many" "astrocyte: 16.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Bone cancer: 63.7" "Colon - Enteric glia cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Skeletal myofibers: 334882678.2" "Tissue enhanced" "Detected in all" "skeletal muscle: 167437583.9" "CAB040547, HPA055972, HPA055973" Approved Supported "Vesicles,Microtubules,Cytokinetic bridge,Primary cilium tip,Primary cilium transition zone,Cytosol" Yes NA 1600000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 8 Cytosol "Vesicles, Microtubules, Cytokinetic bridge, Primary cilium tip, Primary cilium transition zone" "CAB040547: , HPA055972: , HPA055973: " "unprognostic (3.14e-1)" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (2.26e-2)" "unprognostic (8.71e-2)" "unprognostic (6.46e-2)" "unprognostic (1.21e-1)" "unprognostic (2.00e-1)" "unprognostic (2.77e-1)" "unprognostic (4.84e-2)" "unprognostic (6.67e-2)" "potential prognostic favorable (4.45e-4)" "unprognostic (2.05e-3)" "unprognostic (7.75e-2)" "potential prognostic favorable (3.07e-4)" "potential prognostic favorable (3.22e-5)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (5.43e-3)" "unprognostic (2.01e-1)" "unprognostic (9.55e-2)" "unprognostic (4.83e-3)" "unprognostic (2.14e-2)" "unprognostic (3.59e-1)" "unprognostic (3.95e-1)" "unprognostic (4.56e-3)" "unprognostic (2.16e-1)" "unprognostic (2.59e-3)" "unprognostic (2.42e-1)" "unprognostic (5.96e-2)" "unprognostic (7.87e-2)" GSTM3 GST5 ENSG00000134202 "Glutathione S-transferase mu 3" P21266 1 109733932-109741038 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 93.2" "Group enriched" "Detected in many" 4 "Early spermatids: 1991.2;Late primary spermatocytes: 3268.9;Late spermatids: 6017.8" "Cell type enriched" "Detected in all" 6 "Spermatogenic cell types: 6017.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 155.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Collecting ducts: 98846492.9;Distal tubules: 103932349.1;Oocytes: 170057232.5" "Low tissue specificity" "Detected in all" "CAB017130, HPA035190, CAB040583, HPA055972" Enhanced Supported "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" Yes NA 650000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 36 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip, Primary cilium transition zone" "CAB017130: , CAB040583: , HPA035190: , HPA055972: " "unprognostic (1.18e-1)" "unprognostic (1.40e-1)" "unprognostic (5.09e-3)" "unprognostic (3.16e-2)" "unprognostic (1.55e-1)" "unprognostic (2.99e-1)" "unprognostic (1.04e-1)" "unprognostic (6.58e-2)" "unprognostic (4.49e-2)" "unprognostic (4.23e-2)" "potential prognostic favorable (8.40e-5)" "unprognostic (1.76e-2)" "unprognostic (1.63e-1)" "unprognostic (5.17e-3)" "unprognostic (4.49e-2)" "unprognostic (5.89e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (7.14e-2)" "unprognostic (2.48e-1)" "unprognostic (1.74e-1)" "unprognostic (1.16e-1)" "unprognostic (4.82e-3)" "unprognostic (9.17e-2)" "unprognostic (8.77e-2)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (7.00e-6)" "unprognostic (1.50e-2)" "unprognostic (7.79e-2)" "unprognostic (2.94e-2)" "unprognostic (1.49e-1)" GSTM4 ENSG00000168765 "Glutathione S-transferase mu 4" Q03013 1 109656099-109665496 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 128.0" "Cell type enhanced" "Detected in many" "Enteric stem cells: 78.3;Enteric transient amplifying cells: 117.2;Enterocytes: 335.0;Paneth cells: 104.4" "Cell type enhanced" "Detected in all" "Enterocytes: 335.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 9 "eosinophil: 343.9" "Lineage enriched" "Detected in all" 9 "granulocytes: 343.9" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "cerebral cortex: 1168484.0;heart muscle: 293874.5;kidney: 1023788.5;salivary gland: 500710.6" "HPA048652, HPA055972, HPA055973" Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Cytosol" Yes NA 1700000 "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 1: Enterocytes - Absorption and Digestion" 11 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip" "HPA048652: , HPA055972: , HPA055973: " "unprognostic (8.53e-2)" "unprognostic (3.38e-3)" "unprognostic (9.98e-2)" "unprognostic (2.10e-2)" "unprognostic (6.40e-3)" "unprognostic (1.11e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (2.37e-2)" "unprognostic (2.41e-1)" "potential prognostic favorable (2.35e-5)" "unprognostic (1.31e-3)" "unprognostic (6.85e-2)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-2)" "unprognostic (4.64e-2)" "unprognostic (3.77e-2)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (3.44e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (9.86e-2)" "unprognostic (5.54e-2)" "unprognostic (1.56e-1)" "unprognostic (6.59e-2)" "unprognostic (9.68e-3)" "unprognostic (1.69e-1)" "unprognostic (1.38e-1)" "unprognostic (9.33e-2)" GSTM5 ENSG00000134201 "Glutathione S-transferase mu 5" P46439 1 109711780-109775428 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "breast: 874.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 48.9;Hematopoietic stem cells: 90.7;Hepatic stellate cells: 45.2;Leydig cells: 106.9;Mast cells: 342.8;Megakaryocytes: 55.6;Müller glia: 148.3;Ovarian stromal cells: 144.0;Peritubular myoid cells: 107.8" "Cell type enhanced" "Detected in many" "Glial cells: 148.3;Leydig cells: 106.9;Mast cells: 342.8;Stem cells: 90.7;Stromal cells: 144.0" "Group enriched" "Detected in many" 4 "astrocyte: 21.0;Bergmann glia: 38.4;choroid plexus epithelial cell: 20.6;fibroblast: 22.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 52.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "plasmacytoid DC: 3.9" "Lineage enriched" "Detected in single" 4 "dendritic cells: 3.9" "Group enriched" "Detected in some" 10 "Bone cancer: 2.8;head and neck cancer: 1.4" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Pancreas - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 13508387.9;Large ducts: 14497156.6" "Group enriched" "Detected in many" "cerebral cortex: 8660581.9;lymphoid tissue: 3634022.7;ovary: 8161252.6" "HPA055972, HPA055973" Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Primary cilium transition zone,Cytosol" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 55: Breast - Lactation" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 58: Mast cells - Allergic inflammatory responses" 18 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip, Primary cilium transition zone" "HPA055972: , HPA055973: " "unprognostic (2.29e-1)" "unprognostic (1.32e-1)" "unprognostic (1.72e-3)" "unprognostic (1.22e-2)" "unprognostic (3.00e-2)" "unprognostic (1.74e-1)" "unprognostic (7.99e-3)" "unprognostic (4.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.31e-1)" "unprognostic (3.43e-2)" "unprognostic (8.79e-3)" "potential prognostic favorable (9.88e-4)" "unprognostic (2.22e-1)" "unprognostic (1.45e-1)" "unprognostic (6.20e-2)" "unprognostic (1.65e-1)" "unprognostic (3.89e-2)" "unprognostic (2.32e-1)" "unprognostic (3.13e-2)" "unprognostic (8.38e-2)" "unprognostic (1.16e-1)" "unprognostic (7.01e-2)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" "unprognostic (1.16e-3)" "unprognostic (1.23e-1)" GSTP1 "FAEES3, GST3, GSTP" ENSG00000084207 "Glutathione S-transferase pi 1" P09211 11 67583742-67586656 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2859.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 10889.7;Esophageal basal cells: 7640.2;Esophageal suprabasal cells: 12507.9;Respiratory ciliated cells: 4104.7;Respiratory deuterosomal cells: 4315.5;Respiratory secretory cells: 4655.5;Suprabasal keratinocytes: 4210.2" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 10889.7;Basal cells: 7640.2;Suprabasal cells: 12507.9" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 256.0;pericyte: 267.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA019779, HPA019869" Enhanced Supported Mitochondria,Cytosol No No 40000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 42 "Mitochondria, Cytosol" "HPA019779: , HPA019869: " "potential prognostic unfavorable (1.96e-4)" "unprognostic (1.27e-1)" "unprognostic (8.18e-3)" "unprognostic (2.90e-2)" "unprognostic (8.92e-2)" "unprognostic (2.28e-1)" "unprognostic (8.79e-2)" "unprognostic (3.77e-2)" "unprognostic (4.70e-3)" "unprognostic (1.07e-1)" "unprognostic (4.34e-2)" "unprognostic (2.67e-1)" "unprognostic (1.98e-1)" "unprognostic (1.98e-1)" "unprognostic (1.65e-1)" "unprognostic (7.37e-2)" "unprognostic (8.40e-2)" "unprognostic (2.01e-1)" "unprognostic (2.03e-1)" "unprognostic (1.40e-2)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (8.31e-4)" "unprognostic (7.73e-2)" "unprognostic (1.22e-2)" "unprognostic (1.28e-1)" "unprognostic (1.94e-1)" "unprognostic (3.33e-2)" "unprognostic (1.23e-1)" "unprognostic (2.78e-1)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" GSTT2 ENSG00000099984 "Glutathione S-transferase theta 2 (gene/pseudogene)" 22 23980058-23983915 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skin 1: 3.3" "Cell type enhanced" "Detected in some" "Astrocytes: 4.7;Conjunctival goblet cells: 2.9;Ependymal cells: 3.1;Epididymal basal cells: 2.8;Lacrimal acinar cells: 4.5;Melanocytes: 5.6;Oligodendrocyte progenitor cells: 3.6;Schwann cells: 2.8" "Cell type enhanced" "Detected in many" "Glial cells: 4.7;Pigment cells: 5.6" "Low cell type specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" HPA000750 Uncertain Approved Nucleoplasm,Cytosol No NA "Cluster 37: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 61: Schwann cells & Melanocytes - Mixed function" Cytosol Nucleoplasm "HPA000750: " GSTT2B GSTT2P ENSG00000133433 "Glutathione S-transferase theta 2B" P0CG30 22 23957414-23961195 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 79.0;breast: 289.9" "Cell type enhanced" "Detected in some" "Astrocytes: 3.5;Bergmann glia: 2.0;Brain inhibitory neurons: 2.4;Distal convoluted tubule cells: 4.4;Ependymal cells: 2.5;Loop of henle epithelial cells: 6.8;Medullary thymic epithelial cells: 2.4;Microglia: 1.9;Oligodendrocyte progenitor cells: 3.6;Other brain neurons: 3.0;Papillary tip epithelial cells: 5.1;Proximal tubule cells: 3.8;Renal collecting duct intercalated cells: 3.5;Renal collecting duct principal cells: 5.6;Renal connecting tubule cells: 5.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 2.5;Ductal cells: 5.6;Glial cells: 3.6;Neuronal cells: 3.0;Renal nephron cells: 6.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA000750 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 105: Non-specific - Mixed function" 1 Cytosol Nucleoplasm "HPA000750: " "unprognostic (1.76e-3)" "unprognostic (2.84e-2)" "unprognostic (9.98e-2)" "unprognostic (9.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.75e-2)" "unprognostic (3.82e-1)" "unprognostic (4.32e-2)" "unprognostic (2.62e-1)" "unprognostic (1.48e-1)" "unprognostic (2.18e-1)" "unprognostic (6.46e-2)" "unprognostic (8.26e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.54e-2)" "unprognostic (7.78e-2)" "unprognostic (2.68e-1)" "unprognostic (3.56e-1)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (3.14e-1)" "unprognostic (3.68e-1)" "unprognostic (9.58e-2)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "unprognostic (3.01e-1)" "unprognostic (1.70e-2)" "unprognostic (2.26e-1)" GSX1 "Gsh-1, GSH1" ENSG00000169840 "GS homeobox 1" Q9H4S2 13 27792483-27794768 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 24 "brain: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 35 "Glioblastoma Multiforme (TCGA): 6.2" "Region enriched" "Detected in single" 19 "hypothalamus: 15.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA047096 Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 14: Myeloid leukemia - Innate immune response" 1 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA047096: " "unprognostic (2.17e-1)" "unprognostic (1.97e-2)" GTF2B TFIIB ENSG00000137947 "General transcription factor IIB" Q00403 1 88852633-88891944 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 11913704.7" "Tissue enhanced" "Detected in many" "bone marrow: 4412526.2" HPA061626 Supported Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 84 "Nucleoplasm, Nuclear bodies" "HPA061626: " "unprognostic (1.47e-1)" "unprognostic (8.60e-2)" "unprognostic (1.69e-2)" "unprognostic (4.58e-2)" "potential prognostic favorable (3.26e-4)" "unprognostic (3.15e-3)" "unprognostic (1.55e-1)" "unprognostic (1.38e-1)" "unprognostic (1.58e-2)" "unprognostic (3.77e-3)" "potential prognostic favorable (1.75e-5)" "unprognostic (1.24e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (7.41e-2)" "unprognostic (2.29e-1)" "unprognostic (2.77e-2)" "unprognostic (2.50e-2)" "unprognostic (3.87e-1)" "unprognostic (1.68e-1)" "unprognostic (3.28e-1)" "unprognostic (5.64e-3)" "unprognostic (4.09e-3)" "unprognostic (2.78e-1)" "unprognostic (1.20e-2)" "unprognostic (1.02e-1)" "unprognostic (6.52e-2)" "unprognostic (1.57e-2)" "unprognostic (3.12e-2)" "unprognostic (3.80e-2)" "unprognostic (3.32e-1)" GTF2H3 "BTF2, P34, TFIIH" ENSG00000111358 "General transcription factor IIH subunit 3" Q13889 12 123633739-123662604 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Neurons: 406494.6;Oocytes: 663483.0" "Tissue enriched" "Detected in single" 19994 "lymphoid tissue: 1999366.9" "HPA004844, HPA053562" Uncertain Supported Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 27 Nucleoplasm "HPA004844: , HPA053562: " "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (1.87e-2)" "unprognostic (1.19e-2)" "unprognostic (1.14e-1)" "unprognostic (5.01e-2)" "unprognostic (2.13e-1)" "unprognostic (5.66e-2)" "unprognostic (5.96e-2)" "unprognostic (3.43e-2)" "potential prognostic favorable (8.93e-4)" "unprognostic (3.06e-1)" "unprognostic (5.33e-1)" "potential prognostic unfavorable (1.45e-5)" "unprognostic (1.53e-1)" "unprognostic (4.45e-2)" "unprognostic (1.25e-3)" "unprognostic (4.07e-2)" "unprognostic (4.04e-1)" "unprognostic (2.07e-1)" "unprognostic (3.75e-2)" "unprognostic (2.03e-2)" "unprognostic (6.84e-3)" "unprognostic (9.13e-2)" "potential prognostic favorable (7.88e-4)" "unprognostic (9.16e-2)" "unprognostic (1.10e-2)" "unprognostic (1.66e-1)" "unprognostic (3.81e-1)" "unprognostic (1.02e-2)" "unprognostic (9.50e-3)" GTF2IRD1 "BEN, Cream1, GTF3, MusTRD1, RBAP2, WBSCR11, WBSCR12" ENSG00000006704 "GTF2I repeat domain containing 1" Q9UHL9 7 74453790-74602605 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 65.9" "Cell type enhanced" "Detected in many" "Myonuclei: 690.1;Renal connecting tubule cells: 420.0;Rod photoreceptor cells: 419.4;Somatotrophs: 571.0" "Cell type enhanced" "Detected in many" "Myocytes: 690.1;Pituitary endocrine cells: 571.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 348 "Collecting ducts: 34771.6" "Not detected" "Not detected" HPA044254 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 24 Nucleoplasm Cytosol "HPA044254: " "potential prognostic favorable (7.96e-4)" "unprognostic (4.26e-2)" "unprognostic (1.56e-1)" "unprognostic (1.01e-1)" "unprognostic (3.13e-1)" "unprognostic (2.65e-2)" "unprognostic (9.13e-2)" "unprognostic (7.82e-2)" "unprognostic (1.09e-1)" "unprognostic (1.91e-1)" "unprognostic (1.63e-3)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (1.01e-3)" "unprognostic (5.58e-2)" "unprognostic (1.18e-2)" "unprognostic (2.71e-1)" "unprognostic (2.21e-1)" "unprognostic (1.15e-1)" "unprognostic (7.15e-2)" "unprognostic (5.45e-2)" "unprognostic (3.18e-3)" "unprognostic (3.26e-3)" "unprognostic (6.69e-2)" "unprognostic (3.50e-3)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (6.17e-4)" "unprognostic (2.31e-1)" "unprognostic (6.61e-2)" "unprognostic (1.72e-1)" "unprognostic (4.64e-2)" GTF3C4 "KAT12, TFIIIC90" ENSG00000125484 "General transcription factor IIIC subunit 4" Q9UKN8 9 132670035-132694953 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" Transcription "Acyltransferase, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA069369 Supported Nucleoplasm,Mitochondria No No "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 31 Nucleoplasm Mitochondria "HPA069369: " "unprognostic (1.06e-1)" "unprognostic (1.45e-2)" "unprognostic (2.60e-1)" "unprognostic (1.83e-1)" "unprognostic (1.26e-1)" "unprognostic (1.99e-2)" "unprognostic (1.32e-1)" "unprognostic (9.49e-3)" "unprognostic (2.39e-1)" "unprognostic (3.70e-1)" "potential prognostic favorable (3.75e-7)" "unprognostic (5.71e-3)" "unprognostic (1.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.84e-2)" "unprognostic (4.25e-2)" "unprognostic (3.40e-3)" "unprognostic (1.36e-1)" "unprognostic (2.40e-2)" "unprognostic (1.26e-1)" "unprognostic (5.63e-2)" "unprognostic (1.80e-1)" "unprognostic (4.56e-1)" "unprognostic (1.16e-2)" "unprognostic (1.72e-3)" "unprognostic (3.91e-1)" "unprognostic (3.91e-1)" "unprognostic (5.11e-2)" "unprognostic (3.23e-1)" "unprognostic (1.47e-1)" "unprognostic (2.25e-1)" GTPBP4 "CRFG, FLJ10686, FLJ10690, NGB, NOG1" ENSG00000107937 "GTP binding protein 4" Q9BZE4 10 988434-1019932 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "fallopian tube: 2071291.8;intestine: 6882312.2;lymphoid tissue: 8067916.5" "HPA039618, HPA056468" Uncertain Supported "Nuclear membrane,Nucleoli,Nucleoli rim" No No 56000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 17: Non-specific - RNA processing" 134 "Nucleoli, Nucleoli rim" "Nuclear membrane" "HPA039618: , HPA056468: " "unprognostic (7.06e-2)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (1.31e-1)" "unprognostic (3.43e-3)" "unprognostic (2.48e-1)" "unprognostic (1.02e-1)" "unprognostic (4.91e-2)" "potential prognostic favorable (5.45e-6)" "unprognostic (5.04e-3)" "unprognostic (6.08e-2)" "unprognostic (6.09e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (3.81e-4)" "validated prognostic unfavorable (7.06e-10)" "validated prognostic unfavorable (5.01e-6)" "unprognostic (2.81e-2)" "unprognostic (8.65e-3)" "unprognostic (2.89e-1)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (3.05e-2)" "potential prognostic unfavorable (2.29e-6)" "unprognostic (3.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.75e-1)" "unprognostic (1.33e-1)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (5.06e-2)" "unprognostic (9.16e-2)" GTPBP8 HSPC135 ENSG00000163607 "GTP binding protein 8 (putative)" Q8N3Z3 3 112990984-113015060 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 140.8;Late primary spermatocytes: 151.0" "Cell type enhanced" "Detected in all" "Myocytes: 140.8;Spermatogenic cell types: 151.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 1909170.4;Large ducts: 1956092.1" "Group enriched" "Detected in some" 114 "lymphoid tissue: 6017.8;pancreas: 16683.3" "HPA034831, HPA058631" Approved Enhanced Mitochondria No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 17: Non-specific - RNA processing" 1 Mitochondria "HPA034831: , HPA058631: " "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (2.65e-2)" "unprognostic (4.99e-2)" "unprognostic (8.29e-2)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (1.09e-2)" "unprognostic (9.43e-2)" "unprognostic (7.06e-3)" "potential prognostic favorable (2.09e-6)" "unprognostic (2.44e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (2.94e-4)" "unprognostic (2.27e-3)" "unprognostic (1.45e-3)" "unprognostic (1.55e-1)" "unprognostic (3.16e-1)" "unprognostic (2.03e-1)" "unprognostic (2.43e-2)" "unprognostic (8.18e-2)" "unprognostic (2.04e-2)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" "unprognostic (4.91e-2)" "unprognostic (7.61e-2)" "unprognostic (1.13e-1)" "unprognostic (2.01e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (1.55e-2)" GTSE1 "B99, GTSE-1, Lnc_bc060912" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.5;lymphoid tissue: 18.2;testis: 7.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 49.4;Early primary spermatocytes: 71.6;Enteric transient amplifying cells: 43.5;Erythrocyte progenitors: 65.6;Esophageal basal cells: 32.4;Extravillous trophoblasts: 40.4;Gastric progenitor cells: 35.9;Hofbauer cells: 42.5;Late primary spermatocytes: 42.0;Megakaryocyte progenitors: 68.4;Migrating cytotrophoblasts: 33.8;Monocyte progenitors: 158.1;Neutrophil progenitors: 52.0" "Cell type enhanced" "Detected in many" "Erythrocytes: 65.6;Megakaryocytes: 68.4;Mononuclear phagocytes: 158.1;Spermatogenic cell types: 71.6" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 158 "Granulosa cells: 15776.9" "Group enriched" "Detected in some" 1421 "fallopian tube: 213398.3;skin: 70796.3" HPA029457 Supported "Nucleoplasm,Plasma membrane,Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" Yes Yes "Cluster 15: NK-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 21 "Plasma membrane, Centrosome" "Nucleoplasm, Primary cilium, Primary cilium tip, Basal body, Cytosol" "HPA029457: " "unprognostic (1.25e-2)" "unprognostic (2.89e-1)" "potential prognostic favorable (7.05e-5)" "unprognostic (2.74e-1)" "unprognostic (2.10e-2)" "unprognostic (9.93e-2)" "unprognostic (1.19e-1)" "unprognostic (3.71e-2)" "unprognostic (6.60e-2)" "potential prognostic unfavorable (1.69e-4)" "validated prognostic unfavorable (1.96e-8)" "validated prognostic unfavorable (8.71e-7)" "potential prognostic unfavorable (1.77e-8)" "validated prognostic unfavorable (2.08e-8)" "validated prognostic unfavorable (1.20e-5)" "validated prognostic unfavorable (4.82e-6)" "validated prognostic unfavorable (4.23e-4)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.38e-2)" "unprognostic (3.05e-2)" "potential prognostic unfavorable (2.28e-5)" "unprognostic (1.39e-2)" "unprognostic (3.12e-3)" "unprognostic (1.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (3.20e-2)" "unprognostic (4.77e-1)" "unprognostic (1.54e-1)" GUCA1B "GCAP2, RP48" ENSG00000112599 "Guanylate cyclase activator 1B" Q9UMX6 6 42183284-42194956 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 79 "retina: 432.4" "Group enriched" "Detected in many" 37 "Cone photoreceptor cells: 1039.2;Rod photoreceptor cells: 435.6" "Cell type enriched" "Detected in many" 53 "Neuronal cells: 1039.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 6817 "skeletal muscle: 681659.0" HPA055479 Enhanced Approved "Nucleoplasm,Nuclear membrane,Microtubules,Primary cilium,Basal body" NA NA "Cluster 42: Retina - Visual perception" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "Microtubules, Primary cilium" "Nucleoplasm, Nuclear membrane, Basal body" "HPA055479: " "unprognostic (1.19e-1)" "unprognostic (3.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.08e-1)" "unprognostic (1.31e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.93e-2)" "unprognostic (6.76e-2)" "unprognostic (6.33e-2)" "unprognostic (1.09e-1)" "unprognostic (5.45e-2)" "unprognostic (1.22e-1)" "unprognostic (2.67e-3)" GUCY1A1 "GC-SA3, GUC1A3, GUCY1A3" ENSG00000164116 "Guanylate cyclase 1 soluble subunit alpha 1" Q02108 4 155666726-155737059 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 212.4;Hematopoietic stem cells: 538.6;Pericytes: 288.1;Prostatic glandular cells: 549.7;Retinal bipolar cells: 281.2;Thymocytes: 219.4;Vascular smooth muscle cells: 367.1" "Cell type enhanced" "Detected in many" "Glandular cells: 549.7;Mural cells: 367.1;Stem cells: 538.6" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 584.0" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 48.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 8.3;non-classical monocyte: 10.1;plasmacytoid DC: 11.5" "Group enriched" "Detected in many" 35 "dendritic cells: 11.5;monocytes: 10.1;NK-cells: 8.3" "Cancer enhanced" "Detected in many" "prostate cancer: 29.1" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 3246006.6" "Low tissue specificity" "Detected in many" "CAB010887, HPA056004, HPA058617" Uncertain Supported Nucleoplasm NA NA 11000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 35: Non-specific - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 2 Nucleoplasm "CAB010887: , HPA056004: , HPA058617: " "unprognostic (3.45e-2)" "unprognostic (8.61e-2)" "unprognostic (9.27e-3)" "unprognostic (6.29e-2)" "unprognostic (7.79e-2)" "unprognostic (1.33e-1)" "unprognostic (8.83e-3)" "unprognostic (7.31e-3)" "unprognostic (3.93e-3)" "validated prognostic favorable (1.33e-6)" "validated prognostic favorable (4.13e-6)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (5.94e-4)" "unprognostic (2.65e-1)" "unprognostic (8.38e-2)" "unprognostic (7.93e-3)" "unprognostic (6.44e-3)" "unprognostic (2.44e-1)" "unprognostic (2.00e-1)" "unprognostic (9.77e-2)" "unprognostic (1.61e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (4.77e-4)" "unprognostic (1.41e-1)" "unprognostic (1.29e-2)" "unprognostic (1.74e-3)" "unprognostic (9.73e-2)" "unprognostic (2.56e-1)" GUCY1B1 "GC-S-beta-1, GC-SB3, GUC1B3, GUCY1B3" ENSG00000061918 "Guanylate cyclase 1 soluble subunit beta 1" Q02153 4 155758992-155807811 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "cGMP biosynthesis" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain inhibitory neurons: 125.3;Hematopoietic stem cells: 111.1;Megakaryocyte progenitors: 136.9;Megakaryocytes: 717.1;Pericytes: 169.2;Platelets: 535.8;Retinal bipolar cells: 86.9;Vascular smooth muscle cells: 134.8" "Cell type enhanced" "Detected in many" "Megakaryocytes: 717.1;Platelets: 535.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "intermediate monocyte: 7.2;non-classical monocyte: 24.0" "Lineage enriched" "Detected in many" 13 "monocytes: 24.0" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 14281107.7;Microglia and Neuropil: 17361095.7;Neurons: 24721453.4" "Tissue enhanced" "Detected in many" "cerebral cortex: 12575931.9" "CAB010890, HPA020870, HPA077706" Approved Approved Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 55: Lymphoma - Immune response" "Cluster 110: Mural cells - ECM organization" 6 Cytosol "CAB010890: , HPA020870: , HPA077706: " "unprognostic (2.17e-2)" "unprognostic (1.71e-1)" "unprognostic (3.00e-1)" "unprognostic (1.29e-2)" "unprognostic (1.13e-1)" "unprognostic (7.26e-3)" "unprognostic (1.32e-2)" "unprognostic (1.28e-2)" "unprognostic (2.37e-1)" "validated prognostic favorable (4.35e-4)" "validated prognostic favorable (9.04e-5)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (1.02e-1)" "unprognostic (3.71e-3)" "unprognostic (7.76e-3)" "unprognostic (2.65e-1)" "unprognostic (7.32e-3)" "unprognostic (8.45e-2)" "unprognostic (6.21e-2)" "unprognostic (1.03e-1)" "unprognostic (2.71e-1)" "unprognostic (5.46e-1)" "unprognostic (6.39e-2)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (8.98e-6)" "unprognostic (5.30e-3)" "unprognostic (1.67e-2)" "unprognostic (1.68e-1)" "unprognostic (5.69e-2)" GUSB ENSG00000169919 "Glucuronidase beta" P08236 7 65960684-65982215 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Cancer-related genes, Disease variant, Mucopolysaccharidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.3;Kupffer cells: 152.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "liver: 138777553.5" "HPA036322, HPA036323" Approved Supported Vesicles "Intracellular and membrane" Enzyme NA NA 560000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 3 Vesicles "HPA036322: , HPA036323: " "unprognostic (3.12e-1)" "unprognostic (1.04e-1)" "unprognostic (2.72e-1)" "unprognostic (9.64e-2)" "unprognostic (2.48e-1)" "unprognostic (2.55e-3)" "unprognostic (1.85e-2)" "unprognostic (1.62e-3)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (6.76e-4)" "potential prognostic favorable (8.02e-5)" "unprognostic (1.44e-1)" "unprognostic (4.40e-2)" "unprognostic (1.49e-1)" "unprognostic (4.04e-2)" "unprognostic (9.19e-3)" "unprognostic (7.99e-2)" "unprognostic (8.55e-2)" "unprognostic (6.15e-2)" "unprognostic (4.35e-2)" "unprognostic (5.20e-3)" "unprognostic (4.67e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-3)" "unprognostic (1.86e-2)" "unprognostic (4.24e-1)" "unprognostic (4.80e-2)" "unprognostic (2.30e-1)" "unprognostic (9.33e-2)" "unprognostic (1.34e-2)" GXYLT1 "FLJ43151, GLT8D3" ENSG00000151233 "Glucoside xylosyltransferase 1" Q4G148 12 42081845-42144874 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 3286981.9" "Tissue enhanced" "Detected in many" "skeletal muscle: 128040.4" HPA077997 Approved "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme NA NA 790000 "Cluster 25: Non-specific - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Endoplasmic reticulum" Vesicles "HPA077997: " "unprognostic (1.24e-1)" "unprognostic (2.11e-3)" "unprognostic (2.71e-1)" "unprognostic (3.72e-2)" "unprognostic (1.25e-1)" "unprognostic (2.73e-2)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (9.79e-4)" "unprognostic (7.77e-2)" "unprognostic (5.30e-3)" "potential prognostic favorable (6.86e-4)" "unprognostic (3.64e-2)" "unprognostic (3.60e-2)" "unprognostic (5.91e-3)" "unprognostic (2.79e-2)" "unprognostic (2.67e-3)" "unprognostic (2.33e-2)" "unprognostic (5.29e-3)" "unprognostic (9.64e-2)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (5.96e-2)" "unprognostic (1.61e-3)" "unprognostic (1.12e-1)" "unprognostic (2.98e-1)" "unprognostic (6.49e-2)" "unprognostic (4.04e-2)" "unprognostic (2.46e-1)" "unprognostic (5.01e-1)" "unprognostic (5.35e-2)" "unprognostic (4.27e-2)" GXYLT2 GLT8D4 ENSG00000172986 "Glucoside xylosyltransferase 2" A0PJZ3 3 72888046-72998138 "Enzymes, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 115.4;Fibro-adipogenic progenitors: 112.0;Medullary thymic epithelial cells: 120.0;Mesothelial cells: 189.1;Myosatellite cells: 203.1" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 189.1;Stem cells: 203.1" "Cell type enhanced" "Detected in many" "fibroblast: 125.4;oligodendrocyte: 121.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Smooth muscle cells: 165981.8" "Tissue enhanced" "Detected in many" "blood vessel: 15589.0" HPA068429 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Midbody ring" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Cytokinetic bridge, Midbody ring" "HPA068429: " "unprognostic (2.87e-1)" "unprognostic (1.22e-2)" "unprognostic (3.86e-2)" "unprognostic (2.02e-2)" "unprognostic (1.14e-1)" "unprognostic (3.89e-1)" "unprognostic (1.87e-2)" "unprognostic (1.16e-2)" "unprognostic (4.81e-2)" "unprognostic (7.42e-3)" "unprognostic (2.81e-3)" "unprognostic (1.59e-1)" "unprognostic (1.63e-2)" "unprognostic (2.37e-1)" "unprognostic (1.61e-2)" "unprognostic (9.67e-2)" "unprognostic (6.89e-3)" "unprognostic (1.63e-2)" "unprognostic (3.78e-2)" "unprognostic (2.14e-1)" "unprognostic (3.42e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (1.68e-2)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (6.57e-2)" "unprognostic (4.44e-2)" "unprognostic (9.82e-2)" GYG2 GN-2 ENSG00000056998 "Glycogenin 2" O15488 X 2828822-2882820 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycogen biosynthesis" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 146.8;breast: 40.4" "Group enriched" "Detected in many" 7 "Adipocytes: 580.6;Ependymal cells: 201.9" "Group enriched" "Detected in many" 7 "Adipocytes: 580.6;Ciliated cells: 201.9" "Cell type enhanced" "Detected in many" "astrocyte: 107.8;ependymal cell: 212.8" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 71.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 42.5;testis cancer: 54.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Lung - Respiratory ciliated cells, Skin - Adipocytes (Skin)" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 914720.1;Fallopian tube cells: 604253.3;Hepatocytes: 324987.5" "Tissue enriched" "Detected in some" "liver: 85898228.5" "HPA005495, HPA064686" Enhanced Approved "Nucleoplasm,Nucleoli,Mitotic spindle,Centrosome,Cytosol" Yes No "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 89: Adipocytes - Lipid metabolism" 10 "Nucleoli, Cytosol" "Nucleoplasm, Mitotic spindle, Centrosome" "HPA005495: , HPA064686: " "unprognostic (6.03e-2)" "unprognostic (9.74e-2)" "unprognostic (5.37e-2)" "unprognostic (5.35e-2)" "unprognostic (8.22e-3)" "unprognostic (4.29e-2)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (3.37e-1)" "unprognostic (1.51e-2)" "unprognostic (1.18e-2)" "unprognostic (1.15e-2)" "unprognostic (1.61e-1)" "unprognostic (3.79e-1)" "unprognostic (6.11e-2)" "unprognostic (8.44e-2)" "unprognostic (3.27e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (6.32e-5)" "unprognostic (6.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.10e-3)" "unprognostic (9.49e-2)" "unprognostic (3.81e-2)" "unprognostic (1.80e-1)" "unprognostic (7.42e-2)" "unprognostic (3.34e-2)" "unprognostic (9.80e-2)" H1-0 "H1.0, H1F0, H1FV" ENSG00000189060 "H1.0 linker histone" P07305 22 37805229-37807432 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 667.8" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 2145.2" "Cell type enriched" "Detected in all" 7 "Apical squamous epithelial cells: 2145.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 8.6;granulocytes: 18.3;monocytes: 12.5" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "ovary: 483705650.2" HPA000843 Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments" Yes No 310000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 15: Bone marrow - Innate immune response" "Cluster 16: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 53 "Nucleoplasm, Nuclear bodies" "Golgi apparatus, Actin filaments" "HPA000843: " "potential prognostic favorable (6.40e-4)" "unprognostic (1.94e-1)" "unprognostic (4.06e-2)" "unprognostic (2.66e-2)" "unprognostic (2.19e-1)" "potential prognostic favorable (3.52e-4)" "unprognostic (1.67e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-2)" "unprognostic (5.47e-3)" "unprognostic (7.58e-3)" "potential prognostic favorable (1.33e-4)" "unprognostic (2.72e-1)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.18e-1)" "unprognostic (1.36e-2)" "unprognostic (7.73e-3)" "unprognostic (1.15e-1)" "unprognostic (4.90e-3)" "unprognostic (1.84e-2)" "unprognostic (1.78e-2)" "unprognostic (1.38e-1)" "unprognostic (8.05e-2)" "unprognostic (3.80e-2)" "unprognostic (3.03e-1)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (2.49e-4)" "unprognostic (6.58e-2)" H1-1 "H1.1, H1a, H1F1, HIST1H1A" ENSG00000124610 "H1.1 linker histone, cluster member" Q02539 6 26017032-26017787 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 29.3;Differentiating spermatogonia: 95.8;Early primary spermatocytes: 94.1;Esophageal basal cells: 29.5;Hepatic stellate cells: 12.9;Oocytes: 13.8;Undifferentiated spermatogonia: 20.9" "Group enriched" "Detected in many" 4 "Basal cells: 29.5;Spermatogenic cell types: 95.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" "Granulosa cells: 30223107.5;Pancreas epithelial cells: 7856339.8" "Group enriched" "Detected in many" "fallopian tube: 5999020.7;ovary: 21660166.5" "HPA043753, HPA056830" Enhanced Supported Nucleoplasm NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 199 Nucleoplasm "HPA043753: , HPA056830: " "unprognostic (4.26e-2)" "unprognostic (8.42e-3)" "unprognostic (5.48e-2)" "unprognostic (7.25e-2)" H1-2 "H1.2, H1c, H1F2, H1s-1, HIST1H1C" ENSG00000187837 "H1.2 linker histone, cluster member" P16403 6 26055740-26056470 "Essential proteins, Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 742.5;Esophageal apical cells: 765.6;Monocyte progenitors: 486.6;Pancreatic acinar cells: 1284.5;Plasma cells: 486.5;Platelets: 2148.3" "Cell type enhanced" "Detected in all" "Acinar cells: 1284.5;Platelets: 2148.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 15.2;endothelial cell: 13.0;vascular associated smooth muscle cell: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 259.2;eosinophil: 460.0;neutrophil: 230.5" "Lineage enriched" "Detected in all" 6 "granulocytes: 460.0" "Cancer enhanced" "Detected in all" "Myeloma: 366.4" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 8758 "Pancreatic islets: 875785.7" "Group enriched" "Detected in some" 847 "lymphoid tissue: 134869.4;ovary: 34594.5" "CAB011507, HPA055907" Supported Supported "Nucleoplasm,Nucleoli rim" NA NA 16000000 "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 112 "Nucleoplasm, Nucleoli rim" "CAB011507: , HPA055907: " "unprognostic (6.63e-2)" "unprognostic (2.00e-1)" "potential prognostic favorable (9.10e-4)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.88e-1)" "unprognostic (3.79e-1)" "unprognostic (7.74e-2)" "unprognostic (6.15e-2)" "unprognostic (1.16e-2)" "unprognostic (1.48e-1)" "unprognostic (2.14e-2)" "unprognostic (2.43e-1)" "unprognostic (2.31e-2)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" "unprognostic (4.98e-2)" "unprognostic (3.47e-1)" "unprognostic (1.93e-3)" "unprognostic (1.54e-1)" "unprognostic (2.37e-1)" "unprognostic (2.05e-3)" "unprognostic (6.66e-2)" "unprognostic (1.81e-1)" "unprognostic (6.76e-2)" "unprognostic (9.72e-2)" "unprognostic (1.06e-1)" "unprognostic (7.98e-2)" H1-7 "H1FNT, H1T2, HANP1" ENSG00000187166 "H1.7 linker histone" Q75WM6 12 48328980-48330279 "Predicted intracellular proteins" "Differentiation, DNA condensation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 262 "testis: 207.9" "Group enriched" "Detected in some" 7 "Early spermatids: 2080.0;Late spermatids: 7369.4" "Cell type enriched" "Detected in some" 614 "Spermatogenic cell types: 7369.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA046204 Approved Approved "Perinuclear theca,Connecting piece,Mid piece,Principal piece,End piece" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 85 "Perinuclear theca, Connecting piece, Mid piece, Principal piece, End piece" "HPA046204: " H2AC1 "bA317E16.2, H2AFR, HIST1H2AA" ENSG00000164508 "H2A clustered histone 1" Q96QV6 6 25723397-25726562 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 17 "testis: 5.4" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 172.6;Early primary spermatocytes: 681.1;Late primary spermatocytes: 303.1" "Cell type enriched" "Detected in some" 21 "Spermatogenic cell types: 681.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 Nucleoplasm "HPA041189: " H2AC11 "H2A.1b, H2A/p, H2AFP, HIST1H2AG, pH2A/f" ENSG00000196787 "H2A clustered histone 11" P0C0S8 6 27133043-27133535 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 12.2;testis: 5.5" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 271.8;Erythrocytes: 56.8;Hematopoietic stem cells: 33.5;Megakaryocyte progenitors: 123.1;Megakaryocyte-Erythroid progenitors: 41.7;Monocyte progenitors: 99.7;Neutrophil progenitors: 29.4;Plasma cells: 41.1;Platelets: 71.9" "Cell type enhanced" "Detected in many" "Erythrocytes: 271.8;Megakaryocytes: 123.1;Mononuclear phagocytes: 99.7;Platelets: 71.9" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 4.1;leukocyte: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 60 Nucleoplasm "HPA041189: " "unprognostic (1.79e-1)" "unprognostic (8.81e-3)" "unprognostic (1.51e-1)" "unprognostic (5.69e-2)" "unprognostic (2.01e-1)" "unprognostic (1.97e-2)" "unprognostic (1.45e-1)" "unprognostic (1.60e-2)" "unprognostic (5.15e-3)" "unprognostic (1.82e-1)" "unprognostic (6.09e-2)" "unprognostic (9.75e-2)" "unprognostic (1.90e-1)" "unprognostic (2.01e-1)" "unprognostic (1.22e-2)" "unprognostic (1.65e-2)" "unprognostic (2.50e-1)" "unprognostic (9.06e-2)" "unprognostic (1.57e-1)" "unprognostic (1.62e-2)" "unprognostic (1.79e-1)" "unprognostic (2.40e-2)" "unprognostic (1.77e-1)" "unprognostic (8.67e-2)" "unprognostic (8.62e-2)" "unprognostic (2.72e-2)" "unprognostic (1.14e-1)" H2AC12 "dJ86C11.1, H2A/S, H2AFALii, HIST1H2AH" ENSG00000274997 "H2A clustered histone 12" Q96KK5 6 27147106-27147562 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 8.3" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 215.1;Erythrocytes: 22.7;Megakaryocyte progenitors: 85.2;Monocyte progenitors: 81.1;Neutrophil progenitors: 26.7;Plasma cells: 33.6;Tuft cells: 46.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 215.1;Megakaryocytes: 85.2;Mononuclear phagocytes: 81.1" "Cell type enriched" "Detected in single" 4 "central nervous system macrophage: 1.6" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 14.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004030, HPA041189" Supported Supported Nucleoplasm NA Yes "Cluster 34: B-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 6 Nucleoplasm "CAB004030: , HPA041189: " "unprognostic (5.22e-2)" "unprognostic (5.25e-2)" "unprognostic (1.78e-1)" "unprognostic (3.38e-1)" "unprognostic (2.04e-1)" "unprognostic (1.21e-2)" "unprognostic (1.33e-2)" "unprognostic (5.46e-2)" H2AC13 "H2A/c, H2AFC, HIST1H2AI" ENSG00000196747 "H2A clustered histone 13" P0C0S8 6 27808173-27808667 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 106.7;Erythrocytes: 17.7;Megakaryocyte progenitors: 49.9;Monocyte progenitors: 41.3;Neutrophil progenitors: 8.6;Plasma cells: 12.1" "Group enriched" "Detected in some" 5 "Erythrocytes: 106.7;Megakaryocytes: 49.9;Mononuclear phagocytes: 41.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 54 Nucleoplasm "HPA041189: " "unprognostic (1.53e-3)" "unprognostic (6.10e-2)" "unprognostic (5.43e-3)" "unprognostic (2.22e-1)" "unprognostic (2.96e-1)" "unprognostic (4.04e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (3.48e-2)" "unprognostic (2.71e-2)" "unprognostic (1.38e-3)" "unprognostic (2.68e-2)" "unprognostic (8.36e-3)" "potential prognostic favorable (6.51e-4)" "unprognostic (1.72e-1)" "unprognostic (1.01e-1)" "unprognostic (2.66e-3)" "unprognostic (2.61e-1)" "unprognostic (3.13e-2)" "unprognostic (3.55e-1)" "unprognostic (5.42e-3)" "unprognostic (5.87e-2)" "unprognostic (2.53e-1)" "unprognostic (3.66e-1)" "unprognostic (1.04e-1)" H2AC14 "H2A/E, H2AFE, HIST1H2AJ" ENSG00000276368 "H2A clustered histone 14" Q99878 6 27814302-27814777 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 6.9" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 537.4;Erythrocytes: 118.6;Megakaryocyte progenitors: 227.1;Monocyte progenitors: 193.4;Plasma cells: 55.8" "Group enriched" "Detected in many" 5 "Erythrocytes: 537.4;Megakaryocytes: 227.1;Mononuclear phagocytes: 193.4" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 11.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 2.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA Yes "Cluster 18: Non-specific - Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 19 Nucleoplasm "HPA041189: " "unprognostic (4.79e-3)" "unprognostic (1.84e-2)" "unprognostic (9.22e-3)" "unprognostic (2.78e-1)" "unprognostic (9.55e-2)" "unprognostic (3.94e-2)" "unprognostic (1.92e-1)" "unprognostic (7.08e-2)" "unprognostic (1.09e-2)" "unprognostic (7.42e-2)" "unprognostic (3.68e-1)" "unprognostic (2.48e-1)" H2AC15 "H2A/d, H2AFD, HIST1H2AK" ENSG00000275221 "H2A clustered histone 15" P0C0S8 6 27837880-27838375 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 81.8;Erythrocytes: 11.8;Hematopoietic stem cells: 29.1;Megakaryocyte progenitors: 53.1;Megakaryocyte-Erythroid progenitors: 29.0;Monocyte progenitors: 33.9;NK-cells: 11.6;Plasma cells: 14.8;T-cells: 11.8" "Cell type enhanced" "Detected in many" "Erythrocytes: 81.8;Megakaryocytes: 53.1;Mononuclear phagocytes: 33.9;Stem cells: 29.1" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 47 Nucleoplasm "HPA041189: " "unprognostic (4.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.59e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" "unprognostic (1.93e-2)" "unprognostic (8.71e-3)" "unprognostic (4.20e-3)" "unprognostic (9.56e-2)" H2AC16 "dJ193B12.9, H2A/i, H2AFI, HIST1H2AL" ENSG00000276903 "H2A clustered histone 16" P0C0S8 6 27865317-27865798 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "bone marrow: 7.1" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 353.9;Erythrocytes: 78.8;Megakaryocyte progenitors: 148.2;Monocyte progenitors: 139.6;Neutrophil progenitors: 31.4;Plasma cells: 34.2" "Group enriched" "Detected in many" 6 "Erythrocytes: 353.9;Megakaryocytes: 148.2;Mononuclear phagocytes: 139.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 5.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 47 Nucleoplasm "HPA041189: " "potential prognostic unfavorable (9.44e-4)" "unprognostic (2.28e-2)" "unprognostic (1.85e-3)" "unprognostic (7.73e-2)" "unprognostic (2.58e-1)" "unprognostic (3.29e-1)" "unprognostic (8.94e-3)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (1.21e-2)" "unprognostic (4.20e-1)" "unprognostic (1.60e-1)" H2AC17 "H2A.1, H2A/n, H2AFN, HIST1H2AM" ENSG00000278677 "H2A clustered histone 17" P0C0S8 6 27892699-27893185 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.0" "Group enriched" "Detected in many" 4 "Erythrocyte progenitors: 252.7;Megakaryocyte progenitors: 140.4;Monocyte progenitors: 170.4" "Group enriched" "Detected in many" 4 "Erythrocytes: 252.7;Megakaryocytes: 140.4;Mononuclear phagocytes: 170.4" "Group enriched" "Detected in some" 14 "central nervous system macrophage: 3.3;leukocyte: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 63.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 48 Nucleoplasm "HPA041189: " "unprognostic (1.23e-3)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.03e-1)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (6.42e-3)" "unprognostic (3.86e-1)" "unprognostic (1.17e-3)" "unprognostic (3.46e-2)" "unprognostic (1.44e-2)" "unprognostic (1.74e-2)" "unprognostic (3.73e-3)" "unprognostic (5.56e-2)" "unprognostic (1.16e-2)" "unprognostic (3.65e-3)" "unprognostic (5.57e-3)" "unprognostic (3.68e-1)" "unprognostic (2.41e-1)" "unprognostic (1.56e-1)" "unprognostic (1.94e-1)" "unprognostic (1.84e-1)" "unprognostic (3.35e-1)" "unprognostic (4.66e-2)" "unprognostic (4.91e-2)" H2AC18 "H2A.2, H2A/q, H2AFO, HIST2H2AA, HIST2H2AA3" ENSG00000288825 "H2A clustered histone 18" Q6FI13 1 149842218-149842750 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 82.0;prostate: 54.7" "Cell type enhanced" "Detected in single" "Platelets: 1.4" "Cell type enhanced" "Detected in single" "Platelets: 1.4" "Group enriched" "Detected in some" 19 "choroid plexus: 88.7;pons: 23.6" "Immune cell enriched" "Detected in many" 4 "basophil: 237.7" "Lineage enriched" "Detected in all" 7 "granulocytes: 237.7" "Group enriched" "Detected in many" 5 "lymphoma: 18.2;Myeloma: 30.4;thyroid cancer: 40.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Approved Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 36: Choroid plexus - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 47: Platelets - Hemostasis" 26 Nucleoplasm "HPA041189: " H2AC19 "H2A/r, HIST2H2AA4" ENSG00000288859 "H2A clustered histone 19" Q6FI13 1 149851061-149851594 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 113.5;choroid plexus: 190.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 1926.5" "Lineage enriched" "Detected in all" 9 "granulocytes: 1926.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 102: Non-specific - Mixed function" 3 Nucleoplasm "HPA041189: " H2AC20 "H2A, H2A/q, H2AFQ, HIST2H2AC" ENSG00000184260 "H2A clustered histone 20" Q16777 1 149886918-149887411 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "bone marrow: 23.9" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 334.8;Megakaryocyte progenitors: 158.6;Monocyte progenitors: 209.0;Neutrophil progenitors: 94.3;Plasma cells: 95.0;Tuft cells: 92.2" "Cell type enhanced" "Detected in many" "Erythrocytes: 334.8;Megakaryocytes: 158.6;Mononuclear phagocytes: 209.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 6.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 88 Nucleoplasm "HPA041189: " "unprognostic (3.92e-2)" "unprognostic (6.44e-2)" "unprognostic (4.26e-2)" "unprognostic (1.46e-1)" "unprognostic (6.95e-2)" "unprognostic (3.91e-2)" "unprognostic (6.15e-2)" "unprognostic (2.46e-2)" "unprognostic (3.67e-2)" "potential prognostic unfavorable (9.11e-7)" "unprognostic (1.28e-2)" "unprognostic (2.15e-2)" "unprognostic (6.82e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-1)" "unprognostic (3.86e-3)" "unprognostic (8.10e-2)" "unprognostic (7.10e-3)" "unprognostic (1.33e-2)" "unprognostic (4.77e-2)" "unprognostic (1.35e-1)" "unprognostic (1.31e-2)" "unprognostic (7.42e-3)" "unprognostic (8.01e-2)" "unprognostic (3.78e-1)" "unprognostic (7.60e-2)" "unprognostic (1.85e-2)" "unprognostic (5.92e-2)" H2AC21 HIST2H2AB ENSG00000184270 "H2A clustered histone 21" Q8IUE6 1 149887469-149887965 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "bone marrow: 3.2" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 46.6;Megakaryocyte progenitors: 33.6;Monocyte progenitors: 33.5;Mucous neck cells: 10.7;Neutrophil progenitors: 7.5;Plasma cells: 6.9;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 46.6;Megakaryocytes: 33.6;Mononuclear phagocytes: 33.5" "Cell type enhanced" "Detected in single" "central nervous system macrophage: 1.4" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 4.2;Colon Adenocarcinoma (TCGA): 4.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "CAB011483, HPA041189" Supported Supported Nucleoplasm NA NA 76000000 "Cluster 24: Non-specific - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 109 Nucleoplasm "CAB011483: , HPA041189: " "unprognostic (1.52e-1)" "unprognostic (5.39e-2)" "unprognostic (1.90e-2)" "unprognostic (3.28e-1)" "unprognostic (1.20e-1)" "unprognostic (1.38e-1)" "unprognostic (2.67e-1)" "unprognostic (3.27e-1)" "unprognostic (1.08e-2)" "unprognostic (3.56e-2)" H2AC25 "H2AW, HIST3H2A, MGC3165" ENSG00000181218 "H2A clustered histone 25" Q7L7L0 1 228434777-228457873 "Essential proteins, Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 75.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 13.1;Brain inhibitory neurons: 8.9;Choroid plexus epithelial cells: 4.1;Microglia: 10.9;Oligodendrocyte progenitor cells: 1.7;Oligodendrocytes: 4.1;Other brain neurons: 7.8;Papillary tip epithelial cells: 2.7" "Cell type enhanced" "Detected in some" "Ciliated cells: 4.1;Glial cells: 10.9;Neuronal cells: 13.1;Renal nephron cells: 2.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 1: Neuronal - Visual perception" "Cluster 98: Neurons - Neurotransmission & signaling" 13 Nucleoplasm "HPA041189: " "unprognostic (3.69e-2)" "unprognostic (4.44e-3)" "unprognostic (8.00e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-3)" "validated prognostic favorable (2.15e-4)" "validated prognostic favorable (1.40e-4)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (8.43e-2)" "unprognostic (1.39e-1)" "unprognostic (1.63e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.35e-2)" "unprognostic (2.65e-1)" "unprognostic (1.36e-3)" "unprognostic (4.43e-3)" "unprognostic (1.57e-2)" "unprognostic (1.14e-2)" "unprognostic (2.20e-1)" "unprognostic (7.06e-2)" "unprognostic (2.62e-2)" "unprognostic (1.87e-1)" "unprognostic (2.99e-1)" "unprognostic (3.28e-2)" "unprognostic (5.43e-3)" "unprognostic (2.41e-1)" "unprognostic (3.28e-1)" "unprognostic (1.45e-1)" "unprognostic (3.68e-1)" H2AC4 "H2A/m, H2AFM, HIST1H2AB" ENSG00000278463 "H2A clustered histone 4" P04908 6 26033092-26033618 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.4" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 40.6;Erythrocytes: 7.6;Late spermatids: 5.8;Megakaryocyte progenitors: 20.0;Monocyte progenitors: 24.5;Neutrophil progenitors: 6.7;Plasma cells: 6.2;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 40.6;Megakaryocytes: 20.0;Mononuclear phagocytes: 24.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Colon Adenocarcinoma (TCGA): 4.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 132 Nucleoplasm "HPA041189: " "unprognostic (9.56e-3)" "unprognostic (3.36e-1)" "unprognostic (2.76e-1)" "unprognostic (1.66e-1)" "unprognostic (3.45e-1)" "unprognostic (1.68e-1)" "unprognostic (9.02e-2)" H2AC6 "H2AFL, HIST1H2AC" ENSG00000180573 "H2A clustered histone 6" Q93077 6 26124145-26139116 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in all" 7 "Platelets: 6283.4" "Cell type enriched" "Detected in all" 7 "Platelets: 6283.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 392.5;leukocyte: 179.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1566.8" "Lineage enriched" "Detected in all" 14 "granulocytes: 1566.8" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 18 Nucleoplasm "HPA041189: " "unprognostic (3.13e-3)" "unprognostic (1.49e-1)" "unprognostic (5.94e-2)" "unprognostic (1.85e-2)" "unprognostic (3.42e-2)" "unprognostic (2.37e-1)" "unprognostic (2.92e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.54e-3)" "unprognostic (1.14e-1)" "unprognostic (2.07e-1)" "unprognostic (2.69e-2)" "unprognostic (5.67e-2)" "unprognostic (1.49e-1)" "unprognostic (3.15e-1)" "unprognostic (1.80e-1)" "unprognostic (2.50e-1)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (2.11e-1)" "unprognostic (2.20e-1)" "unprognostic (4.29e-2)" "unprognostic (8.14e-2)" "unprognostic (1.19e-1)" "unprognostic (3.18e-2)" "unprognostic (1.15e-1)" "unprognostic (2.93e-1)" "unprognostic (5.86e-2)" H2AC7 "H2A.3, H2A/g, H2AFG, HIST1H2AD" ENSG00000196866 "H2A clustered histone 7" P20671 6 26198784-26199293 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in single" 18 "Microglia: 4.5" "Cell type enriched" "Detected in single" 32 "Glial cells: 4.5" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 7.7" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 12.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 18.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Mitotic cells (Minor salivary gland)" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Supported Nucleoplasm NA Yes "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 12 Nucleoplasm "HPA041189: " "unprognostic (4.84e-1)" "unprognostic (1.53e-1)" "unprognostic (1.21e-1)" "unprognostic (2.37e-2)" "unprognostic (2.39e-1)" "unprognostic (4.77e-2)" "unprognostic (3.48e-1)" "unprognostic (1.32e-1)" "unprognostic (1.78e-1)" "unprognostic (1.88e-1)" "unprognostic (1.38e-1)" "unprognostic (1.20e-1)" "unprognostic (9.04e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-1)" H2AC8 "H2A.1, H2A/a, H2AFA, HIST1H2AE" ENSG00000277075 "H2A clustered histone 8" P04908 6 26216921-26217437 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 37.1;prostate: 32.7" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 136.5;Erythrocyte progenitors: 64.0;Esophageal apical cells: 64.4;Monocyte progenitors: 43.2;Platelets: 278.1" "Cell type enhanced" "Detected in many" "Platelets: 278.1;Reproductive supporting cells: 136.5" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 9.6;choroid plexus epithelial cell: 2.9" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 68.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" "CAB012242, HPA041189" Supported Supported Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 47: Platelets - Hemostasis" 33 Nucleoplasm "CAB012242: , HPA041189: " "unprognostic (6.74e-3)" "unprognostic (5.11e-2)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (9.94e-4)" "unprognostic (6.45e-2)" "unprognostic (1.77e-1)" "unprognostic (2.32e-1)" "unprognostic (7.60e-2)" "unprognostic (6.61e-2)" "unprognostic (9.42e-2)" "unprognostic (2.66e-1)" "unprognostic (5.18e-2)" "unprognostic (6.61e-3)" "unprognostic (4.74e-2)" "unprognostic (9.11e-3)" "unprognostic (4.24e-3)" "unprognostic (2.25e-1)" "potential prognostic favorable (5.18e-4)" "unprognostic (8.58e-3)" "unprognostic (2.76e-1)" "unprognostic (3.00e-2)" "unprognostic (2.71e-1)" "unprognostic (1.95e-1)" "unprognostic (2.28e-1)" "unprognostic (2.14e-1)" "unprognostic (2.31e-1)" H2AJ "FLJ10903, H2AFJ, MGC921" ENSG00000246705 "H2A.J histone" Q9BTM1 12 14774405-14778002 "Essential proteins, Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 541.3" "Cell type enhanced" "Detected in many" "Early spermatids: 2734.8;Esophageal apical cells: 3319.8;Late primary spermatocytes: 4295.4;Late spermatids: 6091.5;Platelets: 1246.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 3319.8;Spermatogenic cell types: 6091.5" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 45.1" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 1356.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041189 Supported Approved Nucleoplasm NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 8 Nucleoplasm "HPA041189: " "unprognostic (1.66e-1)" "unprognostic (2.68e-1)" "unprognostic (7.16e-2)" "unprognostic (1.72e-1)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (1.43e-5)" "unprognostic (2.71e-3)" "unprognostic (9.32e-3)" "unprognostic (1.35e-2)" "unprognostic (7.91e-3)" "unprognostic (3.83e-3)" "unprognostic (1.05e-2)" "unprognostic (2.81e-3)" "unprognostic (3.46e-2)" "unprognostic (2.38e-2)" "unprognostic (2.22e-1)" "unprognostic (9.02e-3)" "unprognostic (1.52e-1)" "unprognostic (8.21e-2)" "unprognostic (5.30e-2)" "unprognostic (7.19e-2)" "unprognostic (1.32e-2)" "unprognostic (6.39e-2)" "unprognostic (3.07e-2)" "unprognostic (1.84e-1)" "unprognostic (1.83e-1)" "unprognostic (2.04e-2)" "unprognostic (3.01e-2)" "unprognostic (4.25e-1)" H2AX H2AFX ENSG00000188486 "H2A.X variant histone" P16104 11 119093874-119095465 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 199.9;Breast myoepithelial cells: 153.3;Breast secretory cells: 139.8;Epididymal basal cells: 156.9;pDCs: 145.6" "Cell type enhanced" "Detected in many" "Secretory cells: 199.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 729663437.4;T-cells: 746892775.7" "Low tissue specificity" "Detected in many" "CAB012264, HPA041189, HPA051647" Supported Supported "Nucleoplasm,Nuclear speckles" Yes Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 219 Nucleoplasm "Nuclear speckles" "CAB012264: , HPA041189: , HPA051647: " "unprognostic (1.42e-1)" "unprognostic (1.19e-1)" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (2.61e-1)" "unprognostic (2.51e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (6.00e-9)" "unprognostic (4.59e-3)" "unprognostic (2.37e-3)" "potential prognostic unfavorable (1.58e-4)" "potential prognostic unfavorable (9.42e-6)" "unprognostic (1.72e-3)" "unprognostic (3.56e-2)" "unprognostic (1.04e-1)" "unprognostic (2.57e-2)" "unprognostic (2.82e-2)" "unprognostic (8.43e-2)" "unprognostic (7.28e-2)" "unprognostic (2.71e-2)" "unprognostic (2.54e-1)" "unprognostic (2.80e-1)" "unprognostic (4.04e-2)" "unprognostic (2.52e-2)" "unprognostic (1.56e-1)" "unprognostic (3.62e-1)" "unprognostic (5.82e-3)" HABP4 "IHABP4, SERBP1L" ENSG00000130956 "Hyaluronan binding protein 4" Q5JVS0 9 96450169-96491336 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 109.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1345.3" "Cell type enriched" "Detected in many" 12 "Spermatogenic cell types: 1345.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.9;T-cells: 1.6" "Low cancer specificity" "Detected in all" "Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 15244974.7" "Tissue enriched" "Detected in some" "cerebral cortex: 3913575.3" "HPA055969, HPA062366" Enhanced Supported "Nuclear membrane,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 19 "Nuclear membrane" Cytosol "HPA055969: , HPA062366: " "unprognostic (7.52e-2)" "unprognostic (8.02e-2)" "unprognostic (1.20e-1)" "unprognostic (3.18e-1)" "unprognostic (4.54e-2)" "unprognostic (2.56e-2)" "unprognostic (1.35e-1)" "unprognostic (3.72e-3)" "unprognostic (2.00e-1)" "unprognostic (2.52e-1)" "validated prognostic favorable (1.41e-9)" "validated prognostic favorable (1.49e-5)" "unprognostic (1.88e-3)" "unprognostic (7.38e-3)" "unprognostic (1.25e-3)" "unprognostic (7.16e-2)" "unprognostic (2.99e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (4.85e-3)" "unprognostic (3.57e-2)" "unprognostic (8.23e-3)" "unprognostic (3.10e-1)" "unprognostic (2.35e-1)" "unprognostic (3.45e-3)" "unprognostic (3.91e-3)" "unprognostic (2.45e-1)" "unprognostic (3.45e-1)" "unprognostic (2.89e-2)" "unprognostic (3.39e-2)" "unprognostic (1.18e-1)" HACE1 KIAA1320 ENSG00000085382 "HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1" Q8IYU2 6 104728094-104859919 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 28.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 126.3;Retinal horizontal cells: 144.2;Rod photoreceptor cells: 160.7" "Cell type enhanced" "Detected in many" "Neuronal cells: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Hepatocytes: 12533070.9" "Tissue enhanced" "Detected in many" "Stomach: 2304184.1" HPA046071 Supported "Nuclear bodies,Endoplasmic reticulum" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 79: Photoreceptor cells - Phototransduction" 14 "Endoplasmic reticulum" "Nuclear bodies" "HPA046071: " "unprognostic (9.67e-3)" "unprognostic (2.28e-3)" "unprognostic (1.85e-1)" "unprognostic (6.14e-2)" "unprognostic (6.73e-3)" "unprognostic (2.85e-2)" "unprognostic (1.87e-1)" "unprognostic (5.06e-3)" "unprognostic (3.41e-2)" "unprognostic (3.73e-2)" "potential prognostic favorable (9.62e-8)" "unprognostic (3.71e-3)" "unprognostic (1.45e-2)" "unprognostic (9.01e-2)" "unprognostic (2.11e-1)" "unprognostic (1.95e-1)" "unprognostic (7.49e-2)" "unprognostic (2.83e-1)" "unprognostic (1.39e-1)" "unprognostic (3.90e-1)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (8.41e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (5.63e-4)" "unprognostic (1.09e-1)" "unprognostic (6.92e-2)" "unprognostic (7.40e-2)" "unprognostic (3.58e-2)" "unprognostic (4.76e-2)" HACL1 "2-HPCL, HPCL, PHYH2" ENSG00000131373 "2-hydroxyacyl-CoA lyase 1" Q9UJ83 3 15560699-15601852 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 115.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 115.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 12097347.9;Oocytes: 12658766.9;Proximal tubules: 9475205.6" "Tissue enhanced" "Detected in many" "liver: 8871938.2" "HPA035496, HPA035497, HPA073760" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 31: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 89: Adipocytes - Lipid metabolism" 3 Vesicles Nucleoplasm "HPA035496: , HPA035497: , HPA073760: " "unprognostic (1.62e-1)" "unprognostic (6.53e-2)" "unprognostic (7.80e-2)" "unprognostic (5.85e-2)" "unprognostic (5.77e-2)" "unprognostic (4.24e-2)" "unprognostic (1.88e-1)" "unprognostic (4.08e-3)" "unprognostic (2.13e-1)" "unprognostic (4.55e-3)" "potential prognostic favorable (1.54e-4)" "unprognostic (1.11e-1)" "unprognostic (3.49e-2)" "unprognostic (4.20e-2)" "unprognostic (2.07e-1)" "unprognostic (9.81e-2)" "unprognostic (3.13e-1)" "unprognostic (3.62e-2)" "unprognostic (1.62e-1)" "unprognostic (5.37e-2)" "unprognostic (6.94e-2)" "unprognostic (3.94e-2)" "unprognostic (3.79e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (6.53e-6)" "unprognostic (3.05e-2)" "unprognostic (8.43e-3)" "unprognostic (3.31e-1)" "unprognostic (1.83e-2)" "unprognostic (1.29e-2)" "unprognostic (2.87e-2)" HADH "HADH1, HADHSC, SCHAD" ENSG00000138796 "Hydroxyacyl-CoA dehydrogenase" Q16836 4 107989714-108035241 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Fatty acid metabolism, Lipid metabolism, Spermatogenesis" "Oxidoreductase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 225.9;Enteric transient amplifying cells: 237.3;Enterocytes: 337.7;Hepatocytes: 314.6;Parietal cells: 251.0" "Cell type enhanced" "Detected in all" "Enterocytes: 337.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 970426293.6" "Tissue enhanced" "Detected in all" "heart muscle: 533892070.3" "HPA039588, HPA043888" Enhanced Supported Mitochondria No Yes 1100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 6 Mitochondria "HPA039588: , HPA043888: " "unprognostic (4.57e-2)" "unprognostic (2.47e-2)" "unprognostic (2.25e-2)" "unprognostic (1.86e-1)" "unprognostic (1.08e-2)" "unprognostic (3.39e-2)" "unprognostic (2.54e-1)" "unprognostic (8.13e-3)" "unprognostic (6.59e-2)" "potential prognostic unfavorable (2.02e-4)" "potential prognostic favorable (6.62e-13)" "unprognostic (2.15e-3)" "unprognostic (7.66e-3)" "unprognostic (4.79e-3)" "potential prognostic favorable (2.47e-4)" "unprognostic (1.31e-1)" "unprognostic (2.56e-2)" "unprognostic (5.67e-2)" "unprognostic (4.29e-3)" "unprognostic (8.42e-2)" "unprognostic (1.09e-1)" "unprognostic (2.92e-1)" "unprognostic (6.61e-2)" "unprognostic (3.52e-3)" "unprognostic (2.63e-3)" "unprognostic (2.00e-1)" "unprognostic (1.35e-1)" "unprognostic (5.85e-2)" "unprognostic (1.04e-1)" "unprognostic (1.07e-1)" "unprognostic (9.25e-3)" HADHB MTPB ENSG00000138029 "Hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta" P55084 2 26243170-26290465 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 749.3;skeletal muscle: 917.1;tongue: 1024.2" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 476.8;Enterocytes: 444.6;Esophageal apical cells: 515.4;Thymic myoid cells: 499.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1437517639.1" "Tissue enhanced" "Detected in all" "heart muscle: 668925289.1" "HPA037539, HPA037540, HPA066099" Enhanced Supported "Mitochondria,Equatorial segment,Principal piece" No No 130000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 55: Myocytes - Oxidative muscle function" 42 Mitochondria "Equatorial segment, Principal piece" "HPA037539: , HPA037540: , HPA066099: " "unprognostic (5.14e-2)" "unprognostic (2.01e-2)" "unprognostic (2.13e-1)" "unprognostic (2.89e-1)" "unprognostic (2.67e-3)" "unprognostic (2.93e-1)" "unprognostic (1.67e-1)" "unprognostic (2.38e-1)" "unprognostic (4.47e-2)" "unprognostic (9.95e-2)" "potential prognostic favorable (9.73e-12)" "unprognostic (3.45e-2)" "unprognostic (6.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.41e-1)" "unprognostic (1.38e-1)" "unprognostic (3.08e-1)" "unprognostic (1.22e-1)" "unprognostic (2.68e-2)" "unprognostic (1.60e-1)" "unprognostic (2.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.43e-1)" "unprognostic (2.12e-1)" "unprognostic (2.38e-1)" "unprognostic (5.22e-2)" "unprognostic (1.95e-1)" "unprognostic (1.85e-1)" "unprognostic (9.94e-2)" "unprognostic (2.36e-1)" "unprognostic (1.04e-1)" HAUS3 "C4orf15, dgt3, IT1, MGC4701" ENSG00000214367 "HAUS augmin like complex subunit 3" Q68CZ6 4 2227464-2242133 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 25.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.1;Bergmann glia: 3.7;Brain excitatory neurons: 5.0;Brain inhibitory neurons: 3.3;Ependymal cells: 1.6;Microglia: 4.0;Oligodendrocyte progenitor cells: 2.7;Oligodendrocytes: 2.5;Other brain neurons: 3.6" "Group enriched" "Detected in some" 15 "Ciliated cells: 1.6;Glial cells: 4.0;Neuronal cells: 5.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 9424721.4;Macrophages: 19239983.5" "Group enriched" "Detected in some" 18133 "bone marrow: 2421651.1;intestine: 1681050.4;lymphoid tissue: 1337058.6" "HPA040649, HPA048190" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 15: Bone marrow - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 25 "Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Basal body" "HPA040649: , HPA048190: " "unprognostic (9.79e-2)" "unprognostic (7.83e-3)" "unprognostic (1.20e-1)" "unprognostic (1.74e-1)" "unprognostic (3.81e-1)" "unprognostic (1.75e-1)" "unprognostic (3.51e-1)" "unprognostic (4.23e-2)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (5.52e-5)" "unprognostic (1.50e-2)" "unprognostic (5.96e-2)" "unprognostic (6.50e-2)" "unprognostic (1.86e-2)" "unprognostic (8.17e-3)" "unprognostic (2.27e-2)" "unprognostic (2.06e-2)" "unprognostic (1.62e-1)" "unprognostic (7.86e-2)" "unprognostic (3.20e-1)" "unprognostic (6.38e-2)" "unprognostic (8.64e-2)" "unprognostic (9.37e-3)" "unprognostic (4.47e-3)" "unprognostic (1.86e-3)" "unprognostic (6.04e-2)" "unprognostic (3.71e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-1)" "unprognostic (2.97e-2)" "unprognostic (2.31e-1)" HAUS6 "dgt6, FAM29A, FLJ20060, KIAA1574" ENSG00000147874 "HAUS augmin like complex subunit 6" Q7Z4H7 9 19053141-19102904 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 88.0;Early spermatids: 132.1;Erythrocyte progenitors: 101.5;Late primary spermatocytes: 92.2" "Cell type enhanced" "Detected in all" "Erythrocytes: 101.5;Spermatogenic cell types: 132.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 13831080.6" "Group enriched" "Detected in some" "bone marrow: 1770683.9;lymphoid tissue: 462250.7" "HPA020960, HPA020965" Approved Approved "Nuclear speckles,Centriolar satellite,Cytosol,Acrosome,Connecting piece,Mid piece,Principal piece" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 33 "Centriolar satellite, Cytosol, Acrosome" "Nuclear speckles, Connecting piece, Mid piece, Principal piece" "HPA020960: , HPA020965: " "unprognostic (4.97e-2)" "unprognostic (1.90e-1)" "unprognostic (7.29e-2)" "unprognostic (2.81e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (1.31e-1)" "unprognostic (4.91e-2)" "unprognostic (1.89e-1)" "unprognostic (3.21e-3)" "unprognostic (5.89e-2)" "unprognostic (2.03e-1)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (7.60e-5)" "unprognostic (2.80e-2)" "unprognostic (5.28e-2)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (2.55e-2)" "unprognostic (4.57e-2)" "unprognostic (2.55e-1)" "unprognostic (3.20e-1)" "unprognostic (2.09e-2)" "unprognostic (5.32e-3)" "unprognostic (1.14e-2)" "unprognostic (9.53e-3)" "unprognostic (7.00e-2)" "unprognostic (3.45e-2)" "unprognostic (8.78e-2)" "unprognostic (4.87e-1)" "unprognostic (2.17e-2)" "unprognostic (2.69e-2)" HBZ "HBZ-T1, HBZ1" ENSG00000130656 "Hemoglobin subunit zeta" P02008 16 142728-154503 "Predicted intracellular proteins" "Oxygen transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 3.7;testis: 13.9" "Cell type enriched" "Detected in some" 5 "Late spermatids: 226.8" "Cell type enriched" "Detected in some" 35 "Spermatogenic cell types: 226.8" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 74 "Leukemia: 25.2" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Alveolar cell types: 12414761.8" "Low tissue specificity" "Detected in many" "HPA063268, HPA064073, HPA071726" Approved Approved Nucleoplasm,Cytosol NA NA 320000000 "Cluster 67: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 19 Cytosol Nucleoplasm "HPA063268: , HPA064073: , HPA071726: " HCCS "CCHL, MLS" ENSG00000004961 "Holocytochrome c synthase" P53701 X 11111301-11123086 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 68.4;Oocytes: 101.3" "Cell type enhanced" "Detected in many" "Oocytes: 101.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA002946 Approved Enhanced Mitochondria,Cytosol NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 22 Mitochondria Cytosol "HPA002946: " "unprognostic (2.61e-1)" "potential prognostic unfavorable (6.04e-5)" "unprognostic (4.75e-2)" "unprognostic (2.26e-2)" "unprognostic (1.39e-2)" "unprognostic (2.44e-2)" "unprognostic (3.12e-1)" "unprognostic (8.69e-2)" "unprognostic (3.47e-2)" "unprognostic (1.65e-2)" "potential prognostic favorable (1.98e-8)" "unprognostic (3.04e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (6.62e-7)" "unprognostic (1.17e-3)" "unprognostic (1.47e-3)" "unprognostic (4.24e-2)" "unprognostic (8.13e-2)" "unprognostic (3.57e-2)" "unprognostic (4.45e-2)" "unprognostic (9.94e-2)" "unprognostic (1.23e-2)" "unprognostic (2.24e-2)" "unprognostic (5.81e-2)" "unprognostic (1.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.96e-1)" "unprognostic (6.29e-2)" "unprognostic (2.80e-1)" "unprognostic (1.81e-3)" "unprognostic (1.52e-1)" HCFC1R1 "FLJ20568, HPIP" ENSG00000103145 "Host cell factor C1 regulator 1" Q9NWW0 16 3022625-3024286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 479.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 227.0;Hepatic stellate cells: 187.2;Peritubular myoid cells: 171.8;Smooth muscle cells: 188.3;Vascular smooth muscle cells: 229.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA059647 Approved Approved Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Nucleoplasm "HPA059647: " "unprognostic (6.09e-2)" "unprognostic (2.96e-1)" "unprognostic (8.60e-2)" "unprognostic (1.98e-1)" "unprognostic (7.82e-2)" "unprognostic (5.96e-2)" "unprognostic (2.18e-1)" "unprognostic (2.88e-1)" "unprognostic (2.32e-1)" "unprognostic (9.36e-3)" "unprognostic (7.72e-3)" "unprognostic (1.05e-2)" "unprognostic (2.40e-3)" "unprognostic (9.46e-3)" "unprognostic (2.26e-1)" "unprognostic (1.92e-2)" "unprognostic (1.41e-1)" "unprognostic (3.60e-1)" "unprognostic (9.96e-3)" "unprognostic (3.00e-1)" "unprognostic (3.72e-2)" "unprognostic (4.33e-3)" "unprognostic (2.83e-2)" "unprognostic (3.60e-1)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (3.02e-1)" "unprognostic (5.14e-2)" "unprognostic (8.63e-3)" "unprognostic (1.33e-1)" "unprognostic (4.33e-1)" "unprognostic (4.18e-2)" HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 145.0;lymphoid tissue: 290.6" "Cell type enhanced" "Detected in many" "cDC: 293.7;Kupffer cells: 1301.6;Macrophages: 412.0;Monocyte progenitors: 208.8;monocytes: 470.3;Neutrophil progenitors: 443.0;Neutrophils: 1495.5;Syncytiotrophoblasts: 201.4" "Group enriched" "Detected in many" 4 "Mononuclear phagocytes: 1301.6;Neutrophils: 1495.5" "Group enriched" "Detected in many" 16 "central nervous system macrophage: 224.3;leukocyte: 158.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Leukemia: 188.6;lymphoma: 241.0;Myeloma: 214.2" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Skin - Macrophages, Stomach - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 59327563.7;Macrophages: 76393093.2;T-cells: 65954274.1" "Tissue enriched" "Detected in many" "lymphoid tissue: 189071839.0" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 880000 "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Plasma membrane, Cytosol" "HPA019143: " "unprognostic (1.19e-1)" "unprognostic (2.61e-2)" "unprognostic (2.89e-2)" "unprognostic (7.39e-3)" "unprognostic (1.24e-1)" "unprognostic (1.74e-1)" "unprognostic (1.80e-2)" "unprognostic (3.99e-1)" "unprognostic (8.08e-3)" "unprognostic (6.90e-2)" "unprognostic (9.19e-3)" "unprognostic (5.49e-2)" "unprognostic (1.54e-1)" "unprognostic (4.94e-1)" "unprognostic (2.80e-2)" "unprognostic (9.90e-3)" "unprognostic (6.00e-2)" "unprognostic (8.21e-2)" "unprognostic (5.60e-2)" "unprognostic (1.18e-1)" "unprognostic (2.73e-1)" "unprognostic (2.19e-2)" "unprognostic (4.59e-2)" "unprognostic (3.49e-1)" "unprognostic (5.70e-2)" "unprognostic (6.67e-2)" "unprognostic (4.31e-3)" "unprognostic (2.81e-1)" "unprognostic (4.79e-2)" "unprognostic (1.69e-1)" "unprognostic (3.13e-1)" HDAC4 "BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA, KIAA0288" ENSG00000068024 "Histone deacetylase 4" P56524 2 239048168-239401654 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Hydrolase, Repressor" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.2;tongue: 24.9" "Cell type enhanced" "Detected in many" "Myonuclei: 1091.2;Neutrophils: 672.5" "Cell type enhanced" "Detected in all" "Myocytes: 1091.2;Neutrophils: 672.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 32.0;neutrophil: 47.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 47.0" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 12833788.7" "Low tissue specificity" "Detected in many" "HPA048723, HPA071448" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 89 "Nuclear speckles" "Nucleoplasm, Cytosol" "HPA048723: , HPA071448: " "unprognostic (5.13e-2)" "unprognostic (2.60e-1)" "potential prognostic favorable (5.12e-4)" "unprognostic (6.39e-2)" "unprognostic (1.89e-1)" "unprognostic (5.26e-2)" "unprognostic (8.97e-2)" "potential prognostic favorable (2.43e-4)" "unprognostic (1.29e-2)" "unprognostic (5.11e-2)" "unprognostic (6.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (1.23e-2)" "unprognostic (9.01e-2)" "unprognostic (2.83e-1)" "unprognostic (7.20e-2)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (4.11e-1)" "unprognostic (1.95e-3)" "unprognostic (6.59e-2)" "unprognostic (3.31e-2)" "unprognostic (8.41e-3)" "unprognostic (1.30e-2)" "unprognostic (9.53e-2)" "unprognostic (4.29e-1)" "unprognostic (5.74e-2)" "unprognostic (1.87e-2)" "unprognostic (6.70e-2)" HDDC3 "MESH1, MGC45386" ENSG00000184508 "HD domain containing 3" Q8N4P3 15 90929968-90935196 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 74.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 4409230.3" "Low tissue specificity" "Detected in many" HPA040895 Approved Approved Nucleoplasm,Cytosol No No 6200 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 58: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 8 "Nucleoplasm, Cytosol" "HPA040895: " "unprognostic (5.14e-2)" "unprognostic (8.95e-2)" "unprognostic (1.40e-1)" "unprognostic (7.85e-2)" "unprognostic (2.35e-1)" "unprognostic (7.00e-2)" "unprognostic (1.18e-2)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (7.53e-2)" "unprognostic (5.34e-3)" "unprognostic (4.36e-1)" "unprognostic (3.22e-3)" "unprognostic (3.44e-1)" "unprognostic (5.97e-3)" "unprognostic (1.95e-2)" "unprognostic (2.69e-1)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (6.86e-3)" "unprognostic (2.05e-1)" "unprognostic (1.08e-1)" "unprognostic (8.54e-2)" "unprognostic (1.35e-2)" "unprognostic (2.18e-1)" "unprognostic (4.85e-2)" "unprognostic (2.83e-2)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (8.85e-2)" "unprognostic (6.13e-2)" HDGFL2 "Hdgfrp2, HRP2" ENSG00000167674 "HDGF like 2" Q7Z4V5 19 4472297-4502208 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Myogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 85.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 16656171.6" "Tissue enhanced" "Detected in all" "ovary: 58601133.6" "HPA042559, HPA044208" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 18 Nucleoplasm "Mitochondria, Cytosol" "HPA042559: , HPA044208: " "unprognostic (8.41e-3)" "unprognostic (1.14e-1)" "unprognostic (4.77e-2)" "unprognostic (1.99e-1)" "unprognostic (5.44e-2)" "unprognostic (5.06e-2)" "unprognostic (2.20e-2)" "unprognostic (4.73e-2)" "unprognostic (6.63e-2)" "unprognostic (2.26e-1)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (2.49e-1)" "unprognostic (2.67e-2)" "unprognostic (3.36e-1)" "unprognostic (5.18e-2)" "unprognostic (2.38e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (6.01e-5)" "unprognostic (8.83e-2)" "unprognostic (2.26e-2)" "unprognostic (3.01e-1)" "unprognostic (7.00e-2)" "unprognostic (1.46e-1)" "unprognostic (8.17e-2)" "unprognostic (1.29e-1)" "unprognostic (2.15e-1)" "unprognostic (1.22e-2)" HDHD5 CECR5 ENSG00000069998 "Haloacid dehalogenase like hydrolase domain containing 5" Q9BXW7 22 17137511-17165287 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 94.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 60535480.4" "Tissue enhanced" "Detected in many" "heart muscle: 24335128.8" "HPA005548, HPA076973" Approved Enhanced Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 2 Mitochondria "HPA005548: , HPA076973: " "unprognostic (6.40e-2)" "unprognostic (1.97e-3)" "unprognostic (8.66e-2)" "unprognostic (6.76e-3)" "unprognostic (8.35e-3)" "unprognostic (1.20e-1)" "unprognostic (3.01e-3)" "unprognostic (1.40e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (2.76e-5)" "unprognostic (4.93e-2)" "potential prognostic favorable (1.41e-4)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (9.46e-2)" "unprognostic (3.61e-2)" "unprognostic (6.02e-2)" "unprognostic (2.58e-2)" "unprognostic (8.97e-2)" "unprognostic (1.73e-1)" "unprognostic (2.87e-1)" "unprognostic (4.49e-1)" "unprognostic (2.13e-2)" "unprognostic (3.37e-3)" "unprognostic (1.21e-2)" "unprognostic (9.36e-2)" "unprognostic (4.53e-2)" "unprognostic (1.46e-1)" "unprognostic (4.59e-2)" "unprognostic (3.96e-2)" HEATR1 "BAP28, FLJ10359, UTP10" ENSG00000119285 "HEAT repeat containing 1" Q9H583 1 236549005-236604516 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 152.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 22692201.2" "Tissue enriched" "Detected in many" "intestine: 6279764.0" "HPA046917, HPA062200" Approved Enhanced "Nucleoli fibrillar center,Mitochondria" NA NA 15000 "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 40 "Nucleoli fibrillar center" Mitochondria "HPA046917: , HPA062200: " "unprognostic (3.58e-1)" "unprognostic (1.79e-1)" "unprognostic (2.89e-1)" "potential prognostic unfavorable (7.73e-4)" "unprognostic (1.12e-1)" "unprognostic (1.44e-1)" "unprognostic (5.27e-2)" "unprognostic (9.94e-2)" "unprognostic (1.57e-1)" "unprognostic (1.78e-3)" "unprognostic (2.62e-2)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (5.07e-5)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (4.81e-2)" "unprognostic (1.03e-2)" "unprognostic (8.14e-3)" "unprognostic (1.77e-1)" "unprognostic (2.08e-1)" "unprognostic (2.13e-1)" "unprognostic (2.91e-1)" "unprognostic (3.41e-3)" "unprognostic (6.12e-2)" "unprognostic (7.61e-2)" "potential prognostic favorable (5.05e-4)" "unprognostic (2.73e-2)" "unprognostic (4.78e-2)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (7.34e-3)" "unprognostic (4.85e-2)" HEATR3 FLJ20718 ENSG00000155393 "HEAT repeat containing 3" Q7Z4Q2 16 50065967-50107272 "Plasma proteins, Predicted intracellular proteins" "Erythrocyte maturation, Ribosome biogenesis" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 57.1;monocytes: 63.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA041990, HPA058579" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 63 Nucleoplasm Cytosol "HPA041990: , HPA058579: " "unprognostic (4.13e-2)" "unprognostic (1.04e-2)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (7.65e-4)" "unprognostic (5.71e-2)" "unprognostic (2.85e-3)" "unprognostic (6.27e-2)" "unprognostic (1.01e-2)" "unprognostic (9.41e-3)" "unprognostic (9.79e-3)" "unprognostic (1.65e-2)" "unprognostic (2.84e-3)" "unprognostic (1.48e-2)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (4.76e-2)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "unprognostic (1.01e-1)" "unprognostic (4.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.02e-2)" "unprognostic (2.06e-1)" "unprognostic (6.26e-3)" "unprognostic (1.22e-1)" "potential prognostic favorable (5.34e-4)" "unprognostic (9.65e-2)" "unprognostic (3.35e-3)" "unprognostic (9.78e-2)" "unprognostic (4.35e-1)" "unprognostic (3.04e-1)" "unprognostic (5.35e-3)" HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 577.6;Epicardial cells: 395.7;Extravillous trophoblasts: 210.9;Mesothelial cells: 823.4;Rod photoreceptor cells: 203.3;Sertoli cells: 172.5;Vascular endothelial cells: 321.6" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 823.4;Endothelial cells: 321.6;Neuronal cells: 577.6" "Cell type enriched" "Detected in many" 7 "endothelial cell: 788.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "monocytes: 1.3;NK-cells: 2.1;T-cells: 1.1" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Endothelial cells, Liver - Vascular endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6788 "Glomeruli: 380049.0;Granulosa cells: 977612.4" "Group enriched" "Detected in some" 2742 "kidney: 520142.2;lung: 148976.1;lymphoid tissue: 153403.4" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" "Developmental protein" NA NA 55000000 "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mixed function" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 4 Vesicles "Plasma membrane" "HPA010952: , HPA011559: " "unprognostic (1.13e-1)" "unprognostic (4.52e-2)" "unprognostic (1.09e-1)" "unprognostic (4.74e-2)" "unprognostic (3.80e-2)" "unprognostic (4.47e-3)" "unprognostic (2.35e-1)" "unprognostic (1.35e-2)" "unprognostic (8.70e-2)" "unprognostic (4.34e-2)" "potential prognostic favorable (2.02e-6)" "unprognostic (4.91e-3)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (3.88e-2)" "unprognostic (2.55e-3)" "unprognostic (2.79e-1)" "unprognostic (1.58e-1)" "unprognostic (1.55e-2)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.17e-1)" "unprognostic (3.02e-1)" "unprognostic (6.67e-2)" "unprognostic (1.31e-1)" "unprognostic (9.00e-3)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "unprognostic (9.48e-2)" "unprognostic (4.26e-2)" "unprognostic (2.27e-1)" HELLS "LSH, Nbla10143, PASG, SMARCA6" ENSG00000119969 "Helicase, lymphoid specific" Q9NRZ9 10 94545329-94613905 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Developmental protein, Helicase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 155.1;Early primary spermatocytes: 224.4;Erythrocyte progenitors: 137.9;Megakaryocyte progenitors: 117.4;Monocyte progenitors: 107.4;Respiratory deuterosomal cells: 149.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 149.3;Erythrocytes: 137.9;Megakaryocytes: 117.4;Spermatogenic cell types: 224.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 64.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 429194.1;Neutrophils: 294426.8;T-cells: 315880.2" "Tissue enriched" "Detected in single" 55 "lymphoid tissue: 5498.9" "CAB004491, HPA063242" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles" No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 32 Nucleoplasm "Golgi apparatus, Vesicles" "CAB004491: , HPA063242: " "unprognostic (1.77e-1)" "unprognostic (1.57e-1)" "unprognostic (1.95e-1)" "unprognostic (2.86e-3)" "unprognostic (4.31e-1)" "unprognostic (1.34e-1)" "unprognostic (1.65e-1)" "unprognostic (3.93e-2)" "unprognostic (1.10e-1)" "unprognostic (7.32e-3)" "unprognostic (1.04e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (3.39e-4)" "validated prognostic unfavorable (1.33e-5)" "validated prognostic unfavorable (1.68e-4)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.45e-3)" "unprognostic (4.08e-3)" "unprognostic (1.23e-1)" "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (1.81e-3)" "unprognostic (1.66e-3)" "potential prognostic unfavorable (6.42e-5)" "unprognostic (7.41e-2)" "unprognostic (1.12e-2)" "unprognostic (2.05e-3)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (1.95e-2)" "unprognostic (1.62e-2)" HEMGN "CT155, EDAG, NDR" ENSG00000136929 Hemogen Q9BXL5 9 97926791-97944856 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "bone marrow: 232.9" "Cell type enhanced" "Detected in some" "Early spermatids: 1790.2;Erythrocyte progenitors: 544.5;Erythrocytes: 326.5;Hematopoietic stem cells: 174.2;Late spermatids: 2277.6;Megakaryocyte progenitors: 166.5;Megakaryocytes: 463.6;Platelets: 412.4" "Cell type enriched" "Detected in some" 4 "Spermatogenic cell types: 2277.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 5.1" "Group enriched" "Detected in many" 28 "granulocytes: 2.2;NK-cells: 2.0;T-cells: 5.1" "Cancer enriched" "Detected in some" 6 "Leukemia: 14.2" "Liver - Erythroid cells, Lung - Neutrophils_1, Spleen - Erythrocytes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 31924 "Neutrophils: 3192379.2" "Tissue enriched" "Detected in single" 509847 "bone marrow: 50984659.5" "HPA019572, HPA019604, HPA019606" Enhanced Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 13 Nucleoplasm "HPA019572: , HPA019604: , HPA019606: " HEPACAM2 FLJ38683 ENSG00000188175 "HEPACAM family member 2" A8MVW5 7 93188534-93226469 "Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "intestine: 90.3" "Cell type enhanced" "Detected in some" "Epididymal clear cells: 338.9;Goblet cells: 619.3;Neuroendocrine cells: 232.5;Paneth cells: 69.6;Renal collecting duct intercalated cells: 122.6;Respiratory ionocytes: 340.4;Salivary ionocytes: 212.4;Tuft cells: 334.3" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 232.5;Goblet cells: 619.3;Ionocytes: 340.4;Reproductive supporting cells: 338.9;Secretory gland support: 334.3" "Cell type enhanced" "Detected in some" "ependymal cell: 3.7" "Cancer enriched" "Detected in many" 10 "Kidney Chromophobe (TCGA): 172.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 10.1;lung cancer: 25.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Intercalated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Spleen - Erythrocytes, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 202209.4;Proximal tubules: 486120.0" "Not detected" "Not detected" HPA012381 Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes NA 110000 "Cluster 77: Intestine - Digestion" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 70: Intestinal goblet cells - Mucin production" "Vesicles, Mitotic spindle" Nucleoplasm "HPA012381: " "unprognostic (1.57e-1)" "unprognostic (2.56e-3)" "unprognostic (8.46e-2)" "potential prognostic favorable (4.74e-4)" "unprognostic (1.03e-1)" "unprognostic (2.72e-1)" "unprognostic (1.37e-3)" "unprognostic (1.83e-1)" "unprognostic (4.59e-2)" "unprognostic (1.20e-2)" "unprognostic (2.35e-1)" "unprognostic (2.91e-1)" "unprognostic (7.12e-3)" "unprognostic (1.74e-1)" "unprognostic (4.16e-2)" "unprognostic (2.02e-2)" "unprognostic (8.71e-3)" "unprognostic (2.26e-1)" HEPN1 ENSG00000221932 "Hepatocellular carcinoma, down-regulated 1" Q6WQI6 11 124919250-124920677 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 8 "brain: 162.7" "Cell type enhanced" "Detected in some" "Adipocytes: 48.4;Astrocytes: 171.4;Bergmann glia: 250.7;Ependymal cells: 33.9;Müller glia: 29.4;Oligodendrocyte progenitor cells: 77.4;Oligodendrocytes: 158.6" "Cell type enriched" "Detected in some" 5 "Glial cells: 250.7" "Group enriched" "Detected in many" 4 "astrocyte: 145.3;Bergmann glia: 306.2;oligodendrocyte: 186.6;oligodendrocyte precursor cell: 83.6" "Cancer enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 141.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "liver cancer: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043768, HPA063054" Uncertain Approved "Golgi apparatus" Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Golgi apparatus" "HPA043768: , HPA063054: " "unprognostic (1.32e-2)" "unprognostic (9.39e-2)" "unprognostic (1.49e-1)" "unprognostic (5.75e-3)" HERC4 "DKFZP564G092, KIAA1593" ENSG00000148634 "HECT and RLD domain containing E3 ubiquitin protein ligase 4" Q5GLZ8 10 67921899-68075301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 727.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 147.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA045453, HPA070301" Uncertain Approved "Nucleoli fibrillar center,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" 5 "Nucleoli fibrillar center, Cytosol" "Primary cilium, Primary cilium tip" "HPA045453: , HPA070301: " "unprognostic (6.61e-3)" "unprognostic (2.82e-2)" "unprognostic (9.52e-2)" "unprognostic (2.63e-1)" "unprognostic (1.35e-1)" "unprognostic (5.06e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (4.35e-4)" "unprognostic (2.28e-1)" "unprognostic (8.53e-2)" "unprognostic (3.41e-1)" "unprognostic (5.35e-2)" "unprognostic (3.60e-1)" "unprognostic (2.62e-2)" "unprognostic (1.06e-1)" "unprognostic (4.70e-3)" "unprognostic (1.21e-1)" "unprognostic (2.44e-2)" "unprognostic (2.19e-1)" "unprognostic (4.05e-2)" "unprognostic (3.22e-3)" "unprognostic (2.13e-2)" "unprognostic (1.24e-3)" "unprognostic (3.12e-2)" "unprognostic (2.02e-2)" "unprognostic (1.87e-2)" "unprognostic (1.68e-1)" "unprognostic (4.11e-2)" "unprognostic (2.86e-2)" "unprognostic (3.28e-2)" "unprognostic (7.57e-2)" HERPUD2 FLJ22313 ENSG00000122557 "HERPUD family member 2" Q9BSE4 7 35632659-35697459 "Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 373.0;Late spermatids: 984.6;Neutrophils: 228.0" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 984.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 131 "Glomeruli: 9671.3;Neurons: 16527.7" "Not detected" "Not detected" "HPA015630, HPA076087" Approved Approved "Nucleoli,Nucleoli rim" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 16 "Nucleoli, Nucleoli rim" "HPA015630: , HPA076087: " "unprognostic (1.45e-1)" "unprognostic (3.76e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (7.73e-6)" "unprognostic (1.46e-1)" "unprognostic (5.51e-2)" "unprognostic (1.64e-1)" "unprognostic (7.95e-2)" "unprognostic (9.86e-3)" "potential prognostic unfavorable (2.43e-4)" "validated prognostic favorable (2.48e-5)" "validated prognostic favorable (6.80e-4)" "unprognostic (2.37e-1)" "unprognostic (1.49e-1)" "unprognostic (2.47e-1)" "unprognostic (6.91e-2)" "unprognostic (1.99e-1)" "unprognostic (2.03e-1)" "unprognostic (3.11e-1)" "unprognostic (3.87e-2)" "unprognostic (1.51e-2)" "unprognostic (4.14e-1)" "unprognostic (4.09e-3)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (3.70e-2)" "unprognostic (5.83e-2)" "unprognostic (2.26e-3)" "unprognostic (1.74e-1)" HES1 "bHLHb39, FLJ20408, HES-1, HRY" ENSG00000114315 "Hes family bHLH transcription factor 1" Q14469 3 194136148-194138732 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 1050.4;Enteric stem cells: 1531.2;Enteric transient amplifying cells: 1065.2;Epididymal basal cells: 1237.6;Epididymal efferent duct absorptive cells: 1040.7;Epididymal principal cells: 969.1;Esophageal apical cells: 1122.3;Granulosa cells: 1612.3;Müller glia: 1103.8;Prostatic club cells: 1127.0;Prostatic hillock cells: 1245.6" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 1612.3;Stem cells: 1531.2" "Group enriched" "Detected in many" 12 "astrocyte: 200.3;Bergmann glia: 85.5;endothelial cell: 134.8;ependymal cell: 130.0;fibroblast: 62.2;pericyte: 77.6;vascular associated smooth muscle cell: 50.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "eosinophil: 15.6" "Lineage enriched" "Detected in many" 8 "granulocytes: 15.6" "Low cancer specificity" "Detected in all" "Prostate - Urothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA066929 Supported Nucleoplasm NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 20 Nucleoplasm "HPA066929: " "unprognostic (1.49e-2)" "unprognostic (4.67e-3)" "unprognostic (3.64e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (5.50e-4)" "unprognostic (1.34e-1)" "unprognostic (4.71e-2)" "unprognostic (5.00e-3)" "unprognostic (1.10e-1)" "unprognostic (1.17e-2)" "unprognostic (1.33e-1)" "potential prognostic favorable (7.74e-4)" "unprognostic (2.14e-1)" "unprognostic (5.65e-2)" "unprognostic (5.83e-2)" "unprognostic (5.03e-2)" "unprognostic (1.09e-2)" "unprognostic (5.07e-2)" "unprognostic (3.87e-2)" "unprognostic (9.01e-2)" "unprognostic (1.21e-1)" "unprognostic (5.50e-3)" "unprognostic (2.44e-3)" "unprognostic (4.77e-2)" "unprognostic (1.06e-1)" "unprognostic (6.99e-2)" "unprognostic (2.89e-1)" "unprognostic (5.07e-2)" "unprognostic (2.50e-1)" "unprognostic (1.27e-1)" "unprognostic (7.87e-2)" HES5 bHLHb38 ENSG00000197921 "Hes family bHLH transcription factor 5" Q5TA89 1 2528745-2530263 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 15.3;skin 1: 4.8" "Group enriched" "Detected in some" 35 "Astrocytes: 87.3;Bergmann glia: 67.9;Oligodendrocyte progenitor cells: 78.8" "Cell type enriched" "Detected in some" 45 "Glial cells: 87.3" "Group enriched" "Detected in many" 5 "astrocyte: 89.0;Bergmann glia: 84.6;oligodendrocyte precursor cell: 54.0" "Cancer enriched" "Detected in single" 11 "Glioblastoma Multiforme (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065458, HPA076164" Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol" No NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 70: DU4475 - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 Nucleoplasm "Nuclear speckles, Cytosol" "HPA065458: , HPA076164: " "unprognostic (2.77e-2)" "unprognostic (1.22e-1)" "validated prognostic favorable (4.89e-4)" "validated prognostic favorable (3.13e-5)" "unprognostic (1.31e-2)" HES7 bHLHb37 ENSG00000179111 "Hes family bHLH transcription factor 7" Q9BYE0 17 8120592-8124106 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.4" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 2.8;Breast myoepithelial cells: 3.4;Breast secretory cells: 3.9;Early spermatids: 2.2;Epididymal basal cells: 5.7;Ocular epithelial cells: 2.1;Pericytes: 3.2;Retinal amacrine cells: 2.9;Retinal bipolar cells: 2.0;Salivary duct cells: 2.0;Vascular smooth muscle cells: 3.3" "Cell type enhanced" "Detected in some" "Basal cells: 5.7;Secretory cells: 3.9" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 4.4" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 23.2" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 211 "Hepatocytes: 21071.1" "Not detected" "Not detected" HPA072105 Uncertain Approved Nucleoplasm,Nucleoli No NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 15: Non-specific - Transcription" "Cluster 3: Rhabdoid - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 4 Nucleoplasm Nucleoli "HPA072105: " "unprognostic (2.66e-3)" HEXA ENSG00000213614 "Hexosaminidase subunit alpha" P06865 15 72340924-72376420 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant, Gangliosidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 79.2;Decidual stromal cells: 82.5;Hofbauer cells: 105.2;Microglia: 104.8;Syncytiotrophoblasts: 74.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA018082, HPA054583" Supported Supported Vesicles,Cytosol "Intracellular and membrane" Enzyme NA NA 8400000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 58: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Vesicles Cytosol "HPA018082: , HPA054583: " "unprognostic (2.21e-1)" "unprognostic (2.22e-1)" "unprognostic (8.04e-2)" "potential prognostic unfavorable (3.41e-4)" "unprognostic (1.46e-1)" "unprognostic (2.34e-1)" "unprognostic (2.45e-2)" "unprognostic (8.90e-2)" "potential prognostic unfavorable (8.03e-4)" "unprognostic (3.29e-1)" "potential prognostic favorable (3.73e-6)" "unprognostic (7.42e-2)" "unprognostic (5.27e-2)" "unprognostic (3.11e-3)" "unprognostic (1.25e-2)" "unprognostic (3.28e-1)" "unprognostic (8.81e-2)" "unprognostic (8.83e-2)" "unprognostic (5.58e-2)" "unprognostic (2.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.92e-1)" "unprognostic (6.78e-2)" "unprognostic (1.46e-1)" "unprognostic (6.44e-2)" "unprognostic (3.06e-1)" "unprognostic (4.73e-2)" "unprognostic (2.16e-2)" "unprognostic (4.43e-2)" "unprognostic (1.87e-1)" "unprognostic (1.08e-1)" HEXIM1 "CLP-1, EDG1, HIS1, MAQ1" ENSG00000186834 "HEXIM P-TEFb complex subunit 1" O94992 17 45148475-45152099 "Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 270.4;Epididymal basal cells: 290.7;Megakaryocytes: 315.3;Syncytiotrophoblasts: 594.0;Tuft cells: 253.6" "Cell type enhanced" "Detected in many" "Trophoblast cells: 594.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA008926, CAB011625" Supported Enhanced Nucleoplasm,Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 65: Non-specific - Cell growth & division" 82 Nucleoplasm Vesicles "CAB011625: , HPA008926: " "unprognostic (1.67e-1)" "unprognostic (2.11e-1)" "unprognostic (4.53e-2)" "unprognostic (1.48e-2)" "unprognostic (3.15e-1)" "unprognostic (1.40e-1)" "unprognostic (1.99e-1)" "unprognostic (6.56e-2)" "unprognostic (4.47e-1)" "unprognostic (1.86e-3)" "unprognostic (3.50e-3)" "unprognostic (2.40e-3)" "unprognostic (5.88e-2)" "unprognostic (7.20e-2)" "unprognostic (1.83e-1)" "unprognostic (2.71e-2)" "unprognostic (6.35e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (3.35e-4)" "unprognostic (1.19e-1)" "unprognostic (4.09e-1)" "unprognostic (9.48e-2)" "unprognostic (2.01e-2)" "unprognostic (9.51e-3)" "unprognostic (2.87e-1)" "unprognostic (1.87e-1)" "unprognostic (3.05e-2)" "unprognostic (2.59e-1)" "unprognostic (1.57e-1)" "unprognostic (8.00e-2)" "unprognostic (2.21e-3)" HEY2 "bHLHb32, HERP1, HESR2" ENSG00000135547 "Hes related family bHLH transcription factor with YRPW motif 2" Q9UBP5 6 125747664-125761269 "Predicted intracellular proteins, Transcription factors, Transporters" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 70.9;heart muscle: 29.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 54.8;Cardiomyocytes: 156.2;Endometrial luminal cells: 67.0;Epididymal principal cells: 76.9;Fallopian tube ciliated cells: 57.5;Granulosa cells: 164.6;Late primary spermatocytes: 53.8;Late spermatids: 104.8;Müller glia: 68.8;Oocytes: 101.3;Pituitary stem cells: 62.8;Vascular smooth muscle cells: 110.7" "Cell type enhanced" "Detected in many" "Mural cells: 110.7;Myocytes: 156.2;Oocytes: 101.3;Reproductive supporting cells: 164.6;Spermatogenic cell types: 104.8" "Cell type enhanced" "Detected in many" "astrocyte: 79.8;pericyte: 151.4;vascular associated smooth muscle cell: 231.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 956 "fallopian tube: 95566.6" "HPA030205, HPA074851" Approved Approved "Nuclear bodies,Aggresome" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 31 "Nuclear bodies" Aggresome "HPA030205: , HPA074851: " "unprognostic (1.44e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (5.01e-5)" "unprognostic (1.37e-2)" "unprognostic (1.01e-2)" "unprognostic (2.24e-2)" "unprognostic (1.16e-1)" "unprognostic (7.76e-3)" "unprognostic (5.35e-3)" "unprognostic (8.98e-2)" "validated prognostic favorable (1.04e-4)" "validated prognostic favorable (1.18e-5)" "unprognostic (1.70e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (9.66e-4)" "unprognostic (7.50e-2)" "unprognostic (2.59e-1)" "unprognostic (5.97e-2)" "unprognostic (1.97e-1)" "unprognostic (8.68e-2)" "unprognostic (1.73e-1)" "unprognostic (1.17e-1)" "unprognostic (8.09e-2)" "unprognostic (6.42e-2)" "unprognostic (9.14e-2)" "unprognostic (4.39e-3)" "unprognostic (2.51e-1)" "unprognostic (6.12e-2)" "unprognostic (8.23e-2)" "unprognostic (1.31e-3)" "unprognostic (5.38e-2)" HFE "HFE1, HLA-H" ENSG00000010704 "Homeostatic iron regulator" Q30201 6 26087281-26098343 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 27.7;Kupffer cells: 74.8;Platelets: 22.6" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 74.8" "Cell type enhanced" "Detected in many" "fibroblast: 13.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 27275 "Macrophages: 2727495.0" "Tissue enhanced" "Detected in many" "ovary: 16464343.5" "HPA017276, HPA053470" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 22: Epididymis - Mixed function" "Cluster 36: Choroid plexus - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 "Plasma membrane" Nucleoplasm "HPA017276: , HPA053470: " "unprognostic (3.17e-2)" "unprognostic (6.59e-2)" "unprognostic (2.24e-1)" "unprognostic (1.36e-2)" "unprognostic (6.18e-2)" "unprognostic (1.08e-1)" "unprognostic (6.94e-3)" "potential prognostic unfavorable (7.65e-7)" "unprognostic (6.50e-2)" "unprognostic (9.88e-2)" "potential prognostic favorable (1.21e-5)" "unprognostic (9.40e-3)" "unprognostic (2.48e-1)" "unprognostic (2.91e-1)" "unprognostic (2.46e-1)" "unprognostic (9.41e-2)" "unprognostic (5.08e-2)" "unprognostic (3.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.86e-1)" "unprognostic (2.77e-2)" "unprognostic (2.01e-3)" "unprognostic (1.33e-1)" "unprognostic (2.69e-1)" "unprognostic (1.90e-1)" "unprognostic (2.60e-1)" "unprognostic (8.32e-3)" "unprognostic (1.12e-1)" "unprognostic (2.38e-1)" "unprognostic (5.95e-2)" "unprognostic (9.67e-2)" HGD "AKU, HGO" ENSG00000113924 "Homogentisate 1,2-dioxygenase" Q93099 3 120628172-120682269 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Phenylalanine catabolism, Tyrosine catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "kidney: 186.7;liver: 703.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 99.7;Endometrial ciliated cells: 130.9;Endometrial glandular cells: 164.2;Endometrial luminal cells: 179.8;Hepatocytes: 734.0;Neuroendocrine cells: 93.1;Platelets: 143.5;Prostatic glandular cells: 106.8;Proximal tubule cells: 185.9;Renal collecting duct intercalated cells: 123.8" "Cell type enhanced" "Detected in many" "Hepatocytes: 734.0;Luminal cells: 179.8;Renal nephron cells: 185.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 7.1" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 294.2" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.1" "Cancer enhanced" "Detected in many" "Kidney cancer: 42.7;liver cancer: 42.4" "Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" "Glomeruli: 66388911.8;Hepatocytes: 188321495.8;Proximal tubules: 132571202.8" "Tissue enriched" "Detected in many" "liver: 93651686.8" "HPA047374, HPA052359" Enhanced Approved "Golgi apparatus" NA NA 1100000 "Cluster 28: Neutrophils - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 2 "Golgi apparatus" "HPA047374: , HPA052359: " "unprognostic (9.55e-2)" "unprognostic (2.99e-2)" "unprognostic (1.26e-2)" "unprognostic (5.56e-2)" "unprognostic (9.65e-2)" "unprognostic (1.17e-1)" "unprognostic (2.47e-2)" "unprognostic (9.70e-2)" "potential prognostic favorable (5.41e-5)" "unprognostic (1.22e-1)" "unprognostic (1.10e-1)" "unprognostic (1.35e-2)" "potential prognostic favorable (5.41e-5)" "unprognostic (1.67e-2)" "unprognostic (6.29e-2)" "unprognostic (6.50e-3)" "unprognostic (7.38e-3)" "unprognostic (4.15e-3)" "unprognostic (1.27e-1)" "unprognostic (4.72e-2)" "unprognostic (4.39e-2)" "unprognostic (3.16e-1)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (7.14e-4)" "unprognostic (6.62e-2)" "unprognostic (4.83e-3)" "unprognostic (6.25e-2)" HHIPL2 "FLJ13840, KIAA1822L" ENSG00000143512 "HHIP like 2" Q6UWX4 1 222522258-222548104 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 4.5;thyroid gland: 1.9" "Group enriched" "Detected in some" 4 "Early spermatids: 24.1;Late primary spermatocytes: 34.0;Late spermatids: 42.2" "Cell type enriched" "Detected in some" 6 "Spermatogenic cell types: 42.2" "Cell type enhanced" "Detected in some" "endothelial cell: 2.2" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA059673 Enhanced Uncertain Mitochondria,Cytosol "Secreted in other tissues" "No annotated function" No NA "Cluster 21: Testis - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Mitochondria Cytosol "HPA059673: " "unprognostic (1.34e-3)" "unprognostic (1.25e-1)" "unprognostic (3.06e-1)" "unprognostic (1.49e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (2.07e-2)" "unprognostic (6.11e-2)" "potential prognostic unfavorable (9.51e-4)" HIF1AN "DKFZp762F1811, FIH1, FLJ20615, FLJ22027" ENSG00000166135 "Hypoxia inducible factor 1 subunit alpha inhibitor" Q9NWT6 10 100529072-100559998 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 38.9;tongue: 38.1" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 118.8;Late spermatids: 80.1" "Cell type enhanced" "Detected in all" "Myocytes: 118.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 4532021.7" "Tissue enriched" "Detected in many" "blood vessel: 5365122.3" "HPA048742, HPA065302, CAB069903" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 118 Nucleoplasm Cytosol "CAB069903: , HPA048742: , HPA065302: " "unprognostic (1.01e-1)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.59e-2)" "unprognostic (1.13e-1)" "unprognostic (2.44e-1)" "unprognostic (3.59e-1)" "unprognostic (2.01e-3)" "unprognostic (3.56e-1)" "unprognostic (1.27e-2)" "potential prognostic favorable (2.03e-5)" "unprognostic (5.69e-2)" "unprognostic (1.23e-1)" "unprognostic (7.95e-3)" "unprognostic (2.77e-2)" "unprognostic (4.34e-2)" "unprognostic (2.08e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-2)" "validated prognostic unfavorable (2.75e-4)" "validated prognostic unfavorable (6.67e-5)" "unprognostic (6.80e-2)" "unprognostic (4.43e-3)" "unprognostic (5.75e-2)" "unprognostic (3.42e-2)" "unprognostic (1.60e-1)" "unprognostic (8.89e-2)" "unprognostic (1.45e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "unprognostic (4.80e-2)" HIGD1B "CLST11240, CLST11240-15" ENSG00000131097 "HIG1 hypoxia inducible domain family member 1B" Q9P298 17 44846353-44850476 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 48.5;placenta: 98.1" "Cell type enriched" "Detected in many" 4 "Pericytes: 340.9" "Cell type enriched" "Detected in many" 26 "Mural cells: 340.9" "Group enriched" "Detected in many" 26 "pericyte: 452.8;vascular associated smooth muscle cell: 127.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA079501 Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 47: Endothelial cells - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA079501: " "unprognostic (9.31e-2)" "unprognostic (3.85e-2)" "unprognostic (1.88e-1)" "unprognostic (3.74e-2)" "unprognostic (4.34e-2)" "unprognostic (1.26e-1)" "unprognostic (8.32e-2)" "unprognostic (4.57e-2)" "unprognostic (1.04e-2)" "unprognostic (4.74e-2)" "unprognostic (1.83e-2)" "potential prognostic favorable (2.72e-4)" "unprognostic (6.53e-3)" "unprognostic (1.52e-2)" "unprognostic (1.51e-1)" "unprognostic (3.03e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (4.96e-2)" "unprognostic (2.12e-1)" "unprognostic (3.79e-3)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (4.69e-2)" "potential prognostic unfavorable (7.95e-4)" "unprognostic (2.41e-3)" "potential prognostic unfavorable (9.27e-5)" "unprognostic (3.96e-1)" "unprognostic (3.17e-2)" "unprognostic (1.46e-1)" HIKESHI "C11orf73, HSPC138, HSPC179, OPI10" ENSG00000149196 "Heat shock protein nuclear import factor hikeshi" Q53FT3 11 86302211-86345943 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 10043004.8" "Low tissue specificity" "Detected in all" "HPA012708, HPA035063, HPA035064" Approved Approved "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" "Nuclear speckles" "Nucleoplasm, Nuclear bodies" "HPA012708: , HPA035063: , HPA035064: " "unprognostic (1.79e-3)" "unprognostic (5.59e-3)" "unprognostic (9.70e-2)" "unprognostic (8.75e-2)" "unprognostic (1.56e-1)" "unprognostic (8.97e-2)" "unprognostic (3.05e-3)" "unprognostic (1.61e-1)" "unprognostic (1.24e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (3.11e-2)" "unprognostic (1.14e-2)" "unprognostic (8.90e-2)" "unprognostic (3.58e-1)" "unprognostic (1.26e-2)" "unprognostic (1.58e-1)" "unprognostic (8.85e-3)" "unprognostic (5.05e-3)" "unprognostic (8.35e-2)" "unprognostic (8.73e-3)" "unprognostic (1.94e-2)" "unprognostic (1.13e-1)" "unprognostic (2.92e-3)" "unprognostic (2.65e-1)" "potential prognostic favorable (9.95e-4)" "unprognostic (1.45e-1)" HINT2 ENSG00000137133 "Histidine triad nucleotide binding protein 2" Q9BX68 9 35812960-35815354 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 21.8;Hepatocytes: 24.4;Megakaryocytes: 24.7;Parietal cells: 37.1" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 37.1;Hepatocytes: 24.4;Megakaryocytes: 24.7" "Cell type enhanced" "Detected in single" "pericyte: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA020961, HPA059109" Supported Enhanced Mitochondria NA NA 100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "HPA020961: , HPA059109: " "unprognostic (6.14e-2)" "unprognostic (6.57e-3)" "unprognostic (1.34e-1)" "unprognostic (4.10e-3)" "unprognostic (1.61e-1)" "unprognostic (3.25e-2)" "unprognostic (2.42e-1)" "unprognostic (9.86e-2)" "unprognostic (1.17e-1)" "unprognostic (5.81e-2)" "potential prognostic favorable (2.53e-6)" "unprognostic (1.66e-2)" "potential prognostic favorable (4.07e-8)" "unprognostic (3.20e-2)" "unprognostic (5.90e-2)" "unprognostic (2.15e-1)" "unprognostic (3.34e-2)" "unprognostic (2.88e-1)" "unprognostic (4.16e-2)" "unprognostic (8.73e-3)" "unprognostic (7.33e-3)" "unprognostic (1.08e-2)" "unprognostic (8.49e-2)" "unprognostic (4.53e-2)" "unprognostic (1.07e-1)" "unprognostic (7.95e-2)" "unprognostic (1.92e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-2)" "unprognostic (1.59e-1)" "unprognostic (1.84e-1)" HIP1 ILWEQ ENSG00000127946 "Huntingtin interacting protein 1" O00291 7 75533298-75738962 "Cancer-related genes, Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Apoptosis, Differentiation, Endocytosis, Transcription, Transcription regulation" "Actin-binding, Activator" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 532.2;Late spermatids: 2445.9;Loop of henle epithelial cells: 870.4;Oligodendrocyte progenitor cells: 545.9;Oligodendrocytes: 516.1;Renal collecting duct principal cells: 537.3;Vascular smooth muscle cells: 512.0" "Cell type enhanced" "Detected in many" "Renal nephron cells: 870.4;Spermatogenic cell types: 2445.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 575.9;oligodendrocyte precursor cell: 682.4;vascular associated smooth muscle cell: 744.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 9.6;eosinophil: 6.9;neutrophil: 6.8;NK-cell: 3.0;plasmacytoid DC: 3.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA013606, CAB015334, CAB016402, HPA017964" Enhanced Supported "Vesicles,Acrosome,Mid piece,Principal piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 39: Non-specific - Transcription" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 70 Vesicles "Acrosome, Mid piece, Principal piece" "CAB015334: , CAB016402: , HPA013606: , HPA017964: " "unprognostic (2.40e-3)" "unprognostic (1.50e-2)" "unprognostic (1.49e-2)" "unprognostic (4.97e-2)" "unprognostic (2.43e-2)" "unprognostic (2.99e-2)" "unprognostic (3.94e-1)" "unprognostic (2.04e-1)" "unprognostic (1.24e-1)" "unprognostic (1.07e-1)" "validated prognostic favorable (4.60e-4)" "validated prognostic favorable (6.80e-4)" "unprognostic (1.40e-1)" "unprognostic (1.37e-2)" "unprognostic (2.91e-1)" "unprognostic (2.84e-2)" "unprognostic (2.97e-1)" "unprognostic (2.05e-1)" "unprognostic (1.26e-1)" "unprognostic (3.13e-3)" "unprognostic (4.39e-1)" "unprognostic (1.30e-2)" "unprognostic (2.56e-1)" "unprognostic (1.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.24e-2)" "unprognostic (7.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" "unprognostic (5.41e-2)" "unprognostic (3.06e-2)" HIPK1 "KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2" ENSG00000163349 "Homeodomain interacting protein kinase 1" Q86Z02 1 113929324-113977869 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.1" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 293.5;Neutrophil progenitors: 548.7;Neutrophils: 470.5" "Cell type enhanced" "Detected in all" "Neutrophils: 548.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA016664 Approved Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 44: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "Nucleoplasm, Basal body, Cytosol" Centrosome "HPA016664: " "unprognostic (4.75e-2)" "unprognostic (3.63e-1)" "unprognostic (6.23e-2)" "unprognostic (2.24e-1)" "unprognostic (1.61e-2)" "unprognostic (1.92e-1)" "unprognostic (4.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.88e-2)" "unprognostic (4.98e-2)" "validated prognostic favorable (1.99e-4)" "validated prognostic favorable (3.55e-4)" "unprognostic (6.22e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (1.49e-1)" "unprognostic (1.45e-1)" "unprognostic (2.32e-3)" "unprognostic (6.43e-2)" "unprognostic (1.62e-1)" "unprognostic (3.09e-2)" "unprognostic (1.31e-1)" "unprognostic (2.31e-2)" "unprognostic (2.40e-1)" "unprognostic (7.30e-2)" "unprognostic (2.55e-2)" "unprognostic (2.18e-1)" "unprognostic (7.00e-2)" "unprognostic (2.90e-1)" "unprognostic (2.44e-1)" "unprognostic (5.77e-2)" "unprognostic (1.87e-1)" HIPK2 ENSG00000064393 "Homeodomain interacting protein kinase 2" Q9H2X6 7 139561570-139777998 "Enzymes, Plasma proteins, Predicted membrane proteins" "Apoptosis, DNA damage, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 146.1" "Cell type enhanced" "Detected in all" "Plasma cells: 825.1;Somatotrophs: 854.2" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 750.3;oligodendrocyte: 747.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "basophil: 27.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Colon - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 52 "Fallopian tube cells: 5172.2" "Not detected" "Not detected" HPA007611 Supported Supported Nucleoplasm NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 44: Plasma cells - Antibody production & secretion" 52 Nucleoplasm "HPA007611: " "unprognostic (3.55e-2)" "unprognostic (1.46e-2)" "unprognostic (2.19e-2)" "unprognostic (2.17e-3)" "unprognostic (4.80e-2)" "unprognostic (1.41e-1)" "unprognostic (6.61e-2)" "unprognostic (4.69e-3)" "unprognostic (2.04e-1)" "unprognostic (3.98e-2)" "potential prognostic favorable (2.48e-9)" "unprognostic (2.13e-2)" "unprognostic (2.15e-1)" "unprognostic (2.97e-1)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (8.49e-2)" "unprognostic (3.89e-3)" "unprognostic (5.69e-1)" "unprognostic (2.64e-1)" "unprognostic (4.55e-1)" "unprognostic (1.66e-3)" "unprognostic (1.92e-3)" "unprognostic (1.45e-1)" "unprognostic (3.30e-1)" "unprognostic (9.09e-2)" "unprognostic (7.30e-2)" "unprognostic (4.85e-1)" "unprognostic (3.82e-2)" "unprognostic (6.13e-2)" "unprognostic (4.32e-2)" HIPK3 "DYRK6, FIST3, PKY, YAK1" ENSG00000110422 "Homeodomain interacting protein kinase 3" Q9H422 11 33256672-33357023 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1249.2" "Cell type enhanced" "Detected in all" "Neutrophils: 1249.2" "Cell type enhanced" "Detected in all" "ependymal cell: 503.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Capillaries: 378637.0;Cardiomyocytes: 735832.2" "Group enriched" "Detected in some" 1004 "heart muscle: 152776.8;liver: 48092.3" HPA028069 Approved Supported "Nuclear bodies,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 39: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Cytosol "Nuclear bodies" "HPA028069: " "unprognostic (6.91e-2)" "unprognostic (1.15e-1)" "unprognostic (7.65e-2)" "unprognostic (2.16e-3)" "unprognostic (8.79e-2)" "unprognostic (9.70e-2)" "unprognostic (2.47e-1)" "unprognostic (1.27e-1)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (9.17e-5)" "validated prognostic favorable (9.25e-7)" "validated prognostic favorable (7.21e-5)" "unprognostic (9.67e-2)" "unprognostic (8.05e-2)" "unprognostic (4.18e-2)" "unprognostic (2.54e-1)" "unprognostic (4.00e-1)" "unprognostic (4.27e-1)" "unprognostic (1.88e-1)" "unprognostic (2.58e-1)" "unprognostic (2.31e-3)" "unprognostic (3.01e-1)" "unprognostic (2.50e-2)" "unprognostic (1.39e-1)" "unprognostic (1.26e-1)" "unprognostic (1.04e-1)" "unprognostic (2.26e-1)" "unprognostic (8.15e-3)" "unprognostic (2.96e-1)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (9.54e-5)" HIRIP3 ENSG00000149929 "HIRA interacting protein 3" Q9BW71 16 29992330-29996074 "Metabolic proteins, Predicted intracellular proteins" "Chaperone, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 84.8;Late primary spermatocytes: 160.9;Megakaryocyte progenitors: 66.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 160.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Macrophages: 231452.6;T-cells: 535852.6" "Tissue enriched" "Detected in some" "bone marrow: 2644477.7" "HPA051897, HPA063205" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 19 Nucleoplasm Nucleoli "HPA051897: , HPA063205: " "unprognostic (4.62e-2)" "unprognostic (2.60e-2)" "unprognostic (1.58e-1)" "unprognostic (2.44e-1)" "unprognostic (4.14e-3)" "unprognostic (1.26e-1)" "unprognostic (2.15e-2)" "potential prognostic favorable (4.18e-4)" "unprognostic (1.31e-1)" "unprognostic (5.62e-2)" "potential prognostic favorable (1.58e-5)" "unprognostic (3.10e-2)" "unprognostic (1.76e-3)" "unprognostic (6.39e-2)" "unprognostic (5.66e-2)" "unprognostic (1.99e-1)" "unprognostic (3.13e-2)" "unprognostic (2.19e-2)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (8.33e-2)" "unprognostic (6.74e-2)" "unprognostic (1.61e-2)" "unprognostic (9.61e-2)" "unprognostic (5.19e-2)" "unprognostic (1.25e-1)" "unprognostic (6.95e-2)" "unprognostic (5.50e-2)" "unprognostic (1.71e-1)" "unprognostic (1.64e-1)" "unprognostic (1.17e-1)" HIVEP1 "CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A" ENSG00000095951 "HIVEP zinc finger 1" P15822 6 12008762-12164999 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 713.8;pDCs: 481.0" "Cell type enhanced" "Detected in all" "Neutrophils: 713.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1618 "Neurons: 243354.1;Oocytes: 80250.2" "Group enriched" "Detected in some" 233 "lung: 32521.7;salivary gland: 14021.7" "HPA050724, HPA067457" Approved Supported "Nucleoplasm,Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 37 Nucleoplasm "Nuclear bodies, Mitochondria, Cytosol" "HPA050724: , HPA067457: " "unprognostic (1.85e-1)" "unprognostic (1.74e-1)" "unprognostic (3.12e-1)" "unprognostic (2.36e-2)" "unprognostic (1.53e-1)" "unprognostic (8.02e-2)" "unprognostic (5.76e-2)" "unprognostic (2.57e-2)" "unprognostic (1.71e-2)" "unprognostic (2.57e-3)" "potential prognostic favorable (2.13e-4)" "unprognostic (4.76e-3)" "unprognostic (1.14e-1)" "unprognostic (4.53e-2)" "unprognostic (1.74e-1)" "unprognostic (2.08e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (5.79e-2)" "unprognostic (2.23e-1)" "unprognostic (2.56e-2)" "unprognostic (3.83e-2)" "unprognostic (7.22e-2)" "unprognostic (3.62e-1)" "unprognostic (3.09e-3)" "unprognostic (3.77e-2)" "unprognostic (3.10e-1)" "unprognostic (5.63e-2)" "unprognostic (3.29e-1)" "unprognostic (1.21e-1)" "unprognostic (6.20e-2)" HJURP "DKFZp762E1312, FAKTS, hFLEG1, URLC9" ENSG00000123485 "Holliday junction recognition protein" Q8NCD3 2 233833416-233854566 "Essential proteins, Predicted intracellular proteins" "Cell cycle" "Chaperone, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.7;lymphoid tissue: 28.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 27.2;Early spermatids: 17.5;Enteric transient amplifying cells: 22.5;Erythrocyte progenitors: 53.1;Extravillous trophoblasts: 18.4;Gastric progenitor cells: 20.5;Late primary spermatocytes: 58.7;Megakaryocyte progenitors: 36.2;Monocyte progenitors: 65.5;Neutrophil progenitors: 24.7;Oocytes: 96.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 53.1;Megakaryocytes: 36.2;Mononuclear phagocytes: 65.5;Oocytes: 96.7;Spermatogenic cell types: 58.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7526 "Capillaries: 898163.3;Glomeruli: 606937.3" "Tissue enhanced" "Detected in some" "intestine: 3122355.3" "HPA008436, HPA027261" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 24 "Nucleoplasm, Nucleoli" Cytosol "HPA008436: , HPA027261: " "unprognostic (5.36e-2)" "unprognostic (8.88e-2)" "unprognostic (6.18e-2)" "unprognostic (1.46e-1)" "unprognostic (2.39e-1)" "unprognostic (3.80e-1)" "unprognostic (5.10e-1)" "unprognostic (7.09e-2)" "unprognostic (5.08e-2)" "validated prognostic unfavorable (2.25e-12)" "validated prognostic unfavorable (9.81e-6)" "potential prognostic unfavorable (1.30e-9)" "validated prognostic unfavorable (1.96e-6)" "validated prognostic unfavorable (1.14e-9)" "potential prognostic unfavorable (3.55e-6)" "unprognostic (5.15e-3)" "unprognostic (2.01e-2)" "unprognostic (2.05e-2)" "unprognostic (5.27e-2)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (1.07e-5)" "unprognostic (3.57e-3)" "unprognostic (3.61e-2)" "unprognostic (7.77e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (4.64e-4)" "unprognostic (5.06e-2)" "unprognostic (1.62e-1)" "unprognostic (6.50e-2)" HKDC1 "FLJ22761, FLJ37767" ENSG00000156510 "Hexokinase domain containing 1" Q2TB90 10 69220332-69267552 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 50.4;retina: 43.4" "Cell type enriched" "Detected in many" 4 "Müller glia: 1675.6" "Cell type enriched" "Detected in many" 4 "Glial cells: 1675.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 61.6;ependymal cell: 105.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 5.8;naive CD8 T-cell: 2.3;T-reg: 5.4" "Lineage enriched" "Detected in single" 23 "T-cells: 5.8" "Cancer enhanced" "Detected in many" "Bile duct cancer: 68.7;Kidney cancer: 74.7" "Kidney - Macrophages, Pancreas - Ductal cells" "Region enhanced" "Detected in many" "cerebral cortex: 11.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 19221057.0;Proximal tubules: 37252281.4" "Group enriched" "Detected in some" 52869 "fallopian tube: 5385444.0;intestine: 6843622.0;pancreas: 3631575.7" "HPA064198, HPA064230" Enhanced Enhanced Mitochondria No No "Cluster 11: T-cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 22 Mitochondria "HPA064198: , HPA064230: " "unprognostic (4.11e-2)" "unprognostic (5.09e-3)" "unprognostic (1.90e-1)" "unprognostic (8.18e-3)" "unprognostic (2.47e-1)" "unprognostic (2.75e-1)" "unprognostic (2.73e-1)" "unprognostic (5.71e-2)" "unprognostic (3.21e-2)" "unprognostic (5.88e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (5.55e-3)" "unprognostic (1.44e-1)" "unprognostic (1.83e-1)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (2.87e-3)" "unprognostic (1.67e-1)" "unprognostic (8.64e-2)" "unprognostic (1.01e-3)" "unprognostic (2.21e-1)" "unprognostic (2.67e-2)" "unprognostic (4.48e-2)" "unprognostic (1.90e-2)" "unprognostic (2.41e-1)" "unprognostic (3.35e-1)" "unprognostic (1.97e-3)" "unprognostic (1.50e-1)" HLF MGC33822 ENSG00000108924 "HLF transcription factor, PAR bZIP family member" Q16534 17 55264960-55325187 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 114.4" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 124.7;Hematopoietic stem cells: 119.9;Hepatocytes: 263.7;Müller glia: 94.1;Renal connecting tubule cells: 111.5;Retinal amacrine cells: 206.3;Retinal bipolar cells: 196.0;Retinal horizontal cells: 96.2;Thyrotrophs: 95.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 263.7;Neuronal cells: 206.3" "Cell type enhanced" "Detected in all" "endothelial cell: 472.6" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 14.5" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 166 "T-cells: 16569.9" "Not detected" "Not detected" "HPA068156, HPA071210" Enhanced Nucleoplasm Yes NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 104: Brain endothelial cells - Blood brain barrier" 6 Nucleoplasm "HPA068156: , HPA071210: " "unprognostic (7.70e-2)" "unprognostic (7.94e-2)" "unprognostic (1.67e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (3.19e-1)" "unprognostic (1.59e-3)" "unprognostic (3.60e-2)" "potential prognostic favorable (8.30e-10)" "unprognostic (3.40e-3)" "unprognostic (1.49e-3)" "unprognostic (5.34e-3)" "unprognostic (1.04e-1)" "potential prognostic favorable (2.03e-4)" "unprognostic (4.47e-2)" "unprognostic (4.74e-3)" "potential prognostic favorable (1.06e-5)" "unprognostic (1.64e-3)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "potential prognostic favorable (1.36e-4)" "unprognostic (1.09e-2)" "unprognostic (2.07e-1)" "unprognostic (2.20e-2)" HMBOX1 "FLJ21616, HNF1LA, HOT1, PBHNF" ENSG00000147421 "Homeobox containing 1" Q6NT76 8 28890395-29064764 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 456.2;Pituicytes/FSCs: 386.5;Renal collecting duct intercalated cells: 419.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1021046.2;Neurons: 1435643.7" "Tissue enhanced" "Detected in many" "liver: 595672.3" "HPA055855, HPA058586, CAB070418" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 47: Leukemia - Hemostasis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 84 Nucleoplasm "Nuclear bodies, Cytosol" "CAB070418: , HPA055855: , HPA058586: " "unprognostic (2.15e-1)" "unprognostic (2.51e-1)" "unprognostic (5.11e-2)" "unprognostic (1.44e-1)" "unprognostic (1.26e-2)" "unprognostic (2.24e-1)" "unprognostic (8.34e-2)" "unprognostic (5.77e-3)" "unprognostic (2.14e-1)" "unprognostic (1.46e-2)" "validated prognostic favorable (1.27e-4)" "validated prognostic favorable (8.19e-5)" "unprognostic (2.15e-1)" "unprognostic (2.37e-2)" "unprognostic (2.30e-1)" "unprognostic (1.53e-1)" "unprognostic (6.41e-2)" "unprognostic (3.41e-1)" "unprognostic (2.27e-1)" "unprognostic (1.07e-1)" "unprognostic (1.09e-2)" "unprognostic (1.35e-2)" "unprognostic (5.12e-2)" "unprognostic (2.67e-2)" "unprognostic (2.63e-2)" "unprognostic (2.93e-1)" "unprognostic (5.81e-2)" "unprognostic (3.86e-1)" "unprognostic (2.00e-2)" "unprognostic (5.39e-2)" HMBS "PBGD, PORC, UPS" ENSG00000256269 "Hydroxymethylbilane synthase" P08397 11 119084866-119093834 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 160.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 69.1;Erythrocyte progenitors: 274.0;Erythrocytes: 181.6;Esophageal basal cells: 54.6;Extravillous trophoblasts: 68.4;Migrating cytotrophoblasts: 65.8" "Cell type enhanced" "Detected in all" "Erythrocytes: 274.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 26285909.3" "Tissue enriched" "Detected in many" "bone marrow: 118477918.3" "HPA006114, HPA050659" Supported Approved "Lipid droplets" NA NA 5100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Bone marrow - Innate immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 3 "Lipid droplets" "HPA006114: , HPA050659: " "unprognostic (4.76e-2)" "unprognostic (1.34e-1)" "unprognostic (3.26e-1)" "unprognostic (4.90e-2)" "unprognostic (3.41e-1)" "unprognostic (2.00e-1)" "unprognostic (3.45e-1)" "unprognostic (3.51e-1)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (2.42e-3)" "potential prognostic unfavorable (8.59e-5)" "potential prognostic favorable (3.89e-4)" "unprognostic (1.92e-3)" "potential prognostic unfavorable (7.38e-4)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (2.57e-2)" "unprognostic (5.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.39e-2)" "unprognostic (1.67e-1)" "potential prognostic unfavorable (3.35e-4)" "unprognostic (3.87e-2)" "unprognostic (2.62e-2)" "unprognostic (4.77e-2)" "unprognostic (1.29e-1)" "unprognostic (6.51e-2)" "unprognostic (5.97e-2)" "unprognostic (3.14e-2)" "unprognostic (6.00e-2)" "unprognostic (3.17e-2)" HMGA2 "BABL, HMGIC, LIPO" ENSG00000149948 "High mobility group AT-hook 2" P52926 12 65824460-65966291 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA condensation, Growth regulation, Mitosis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Dwarfism, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.6;testis: 3.6" "Cell type enhanced" "Detected in many" "Endometrial secretory cells: 167.9;Erythrocyte progenitors: 149.9;Granulosa cells: 85.2;Hematopoietic stem cells: 427.5;Megakaryocyte progenitors: 108.4;Megakaryocyte-Erythroid progenitors: 153.6;Pituicytes/FSCs: 455.3" "Cell type enhanced" "Detected in many" "Glial cells: 455.3;Secretory cells: 167.9;Stem cells: 427.5" "Cell type enhanced" "Detected in some" "astrocyte: 11.4;deep-layer near-projecting: 30.0;ependymal cell: 18.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" "Fallopian tube cells: 236815.2;Granulosa cells: 168092.9;Oocytes: 85682.5" "Tissue enriched" "Detected in some" "ovary: 570241.6" "CAB017809, HPA039076" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 23 "Nucleoplasm, Nucleoli, Nucleoli rim" "CAB017809: , HPA039076: " "unprognostic (4.26e-3)" "unprognostic (5.74e-2)" "unprognostic (1.34e-1)" "unprognostic (2.19e-1)" "unprognostic (2.33e-1)" "unprognostic (7.41e-3)" "unprognostic (4.73e-2)" "unprognostic (2.57e-3)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (2.64e-7)" "unprognostic (2.39e-1)" "unprognostic (9.77e-3)" "unprognostic (4.69e-2)" "unprognostic (6.43e-3)" "unprognostic (2.79e-3)" "unprognostic (2.36e-3)" "unprognostic (1.29e-1)" "unprognostic (5.64e-2)" "unprognostic (1.66e-1)" "unprognostic (7.93e-2)" "validated prognostic unfavorable (2.74e-5)" "validated prognostic unfavorable (2.00e-6)" "unprognostic (1.26e-1)" "unprognostic (1.56e-1)" "unprognostic (1.56e-2)" "unprognostic (1.09e-1)" "unprognostic (2.53e-1)" "unprognostic (2.97e-2)" "unprognostic (1.25e-1)" HMGB1 "DKFZp686A04236, HMG1, HMG3, SBP-1" ENSG00000189403 "High mobility group box 1" P09429 13 30456704-30617597 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Autophagy, Chemotaxis, DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 1881.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA003506, CAB005873, HPA073663" Supported Supported Nucleoplasm "Secreted to blood" Immunity NA NA 1500000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 97 Nucleoplasm "CAB005873: , HPA003506: , HPA073663: " "unprognostic (4.29e-1)" "unprognostic (1.76e-1)" "unprognostic (1.57e-1)" "unprognostic (1.58e-3)" "unprognostic (3.77e-1)" "unprognostic (1.50e-1)" "unprognostic (2.67e-1)" "unprognostic (9.94e-2)" "unprognostic (3.54e-2)" "unprognostic (3.79e-2)" "potential prognostic favorable (1.01e-4)" "unprognostic (8.80e-3)" "unprognostic (2.48e-1)" "unprognostic (1.32e-3)" "potential prognostic unfavorable (2.07e-5)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (1.89e-2)" "unprognostic (2.74e-1)" "unprognostic (1.30e-1)" "unprognostic (2.27e-1)" "unprognostic (1.39e-1)" "validated prognostic unfavorable (5.41e-4)" "validated prognostic unfavorable (7.67e-4)" "unprognostic (3.29e-2)" "unprognostic (1.25e-1)" "unprognostic (7.67e-2)" "unprognostic (1.53e-2)" "unprognostic (4.46e-2)" "unprognostic (2.19e-1)" "unprognostic (4.72e-3)" "unprognostic (4.66e-2)" HMGB2 HMG2 ENSG00000164104 "High mobility group box 2" P26583 4 173331376-173334432 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, DNA recombination, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 12 "bone marrow: 2214.7;lymphoid tissue: 874.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 540.2;Early primary spermatocytes: 646.4;Enteric transient amplifying cells: 659.0;Erythrocyte progenitors: 1125.5;Extravillous trophoblasts: 1000.3;Gastric progenitor cells: 638.3;Megakaryocyte progenitors: 538.7;Migrating cytotrophoblasts: 700.1;Monocyte progenitors: 1546.1;Neutrophil progenitors: 1076.2;Neutrophils: 1240.9" "Cell type enhanced" "Detected in all" "Erythrocytes: 1125.5;Mononuclear phagocytes: 1546.1;Neutrophils: 1240.9;Trophoblast cells: 1000.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 802.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 55112213.1;T-cells: 58105442.1" "Tissue enhanced" "Detected in all" "ovary: 219716829.7" "HPA003506, CAB037206, HPA053314, HPA073663" Enhanced Supported "Nucleoplasm,Nucleoli,Principal piece,Annulus" "Secreted to blood" Transcription NA Yes 830000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 111 Nucleoplasm "Nucleoli, Principal piece, Annulus" "CAB037206: , HPA003506: , HPA053314: , HPA073663: " "unprognostic (1.74e-1)" "unprognostic (3.04e-1)" "unprognostic (1.73e-1)" "unprognostic (5.00e-2)" "unprognostic (4.10e-1)" "unprognostic (1.30e-1)" "unprognostic (1.19e-1)" "unprognostic (1.27e-1)" "unprognostic (4.23e-2)" "unprognostic (5.70e-3)" "unprognostic (3.08e-3)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (3.09e-4)" "validated prognostic unfavorable (1.02e-6)" "validated prognostic unfavorable (7.88e-5)" "unprognostic (9.19e-3)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.34e-2)" "unprognostic (6.93e-2)" "unprognostic (7.87e-2)" "unprognostic (1.83e-2)" "unprognostic (1.18e-3)" "unprognostic (7.28e-2)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (2.45e-2)" "unprognostic (1.65e-2)" "unprognostic (9.39e-2)" "unprognostic (1.28e-1)" "unprognostic (9.37e-2)" "unprognostic (2.63e-1)" HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43287470-43313512 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 364.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 590.3;Breast lactating cells: 390.4;Colonocytes: 539.3;Epididymal principal cells: 1140.0;Esophageal apical cells: 526.1;Esophageal suprabasal cells: 633.0;Retinal ganglion cells: 498.3;Suprabasal keratinocytes: 484.9;Urothelial cells: 659.1" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 659.1;Reproductive supporting cells: 1140.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 26543630.1" "Tissue enhanced" "Detected in many" "liver: 39868734.2" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 660000 "Cluster 29: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: , HPA036913: , HPA036914: " "unprognostic (3.64e-1)" "unprognostic (1.28e-1)" "unprognostic (5.13e-2)" "unprognostic (9.33e-3)" "unprognostic (5.20e-2)" "unprognostic (1.14e-1)" "unprognostic (5.08e-2)" "unprognostic (7.53e-2)" "unprognostic (2.88e-2)" "unprognostic (9.11e-3)" "potential prognostic favorable (1.29e-6)" "unprognostic (4.52e-2)" "unprognostic (9.29e-2)" "unprognostic (5.59e-2)" "unprognostic (9.38e-2)" "unprognostic (3.51e-2)" "unprognostic (5.75e-2)" "unprognostic (2.01e-1)" "unprognostic (2.28e-3)" "unprognostic (1.59e-1)" "unprognostic (1.10e-1)" "unprognostic (6.91e-3)" "unprognostic (2.87e-3)" "unprognostic (9.60e-2)" "unprognostic (5.34e-2)" "unprognostic (6.27e-2)" "unprognostic (2.35e-2)" "unprognostic (3.50e-1)" "unprognostic (2.16e-1)" "unprognostic (4.79e-2)" "unprognostic (8.83e-2)" HMGCS2 ENSG00000134240 "3-hydroxy-3-methylglutaryl-CoA synthase 2" P54868 1 119748002-119768905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "liver: 2275.9" "Cell type enhanced" "Detected in many" "Colonocytes: 497.2;Enteric stem cells: 407.2;Enteric transient amplifying cells: 322.5;Gastric chief cells: 196.6;Goblet cells: 275.6;Hepatocytes: 1287.8;Mucous neck cells: 242.3;Renal connecting tubule cells: 147.2;Retinal pigment epithelial cells: 285.6" "Cell type enhanced" "Detected in many" "Enterocytes: 497.2;Hepatocytes: 1287.8;Proliferating cells: 322.5;Stem cells: 407.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 667.0" "Region enriched" "Detected in single" 43 "choroid plexus: 11.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 41.6;colorectal cancer: 63.1;prostate cancer: 43.9" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Cell type enriched" "Detected in many" "Hepatocytes: 3921836178.2" "Tissue enriched" "Detected in many" "lymphoid tissue: 2613967918.6" "HPA027423, HPA027442, CAB032906" Enhanced Approved Mitochondria NA NA 1800000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" Mitochondria "CAB032906: , HPA027423: , HPA027442: " "unprognostic (1.10e-1)" "unprognostic (2.02e-1)" "unprognostic (2.54e-1)" "unprognostic (1.86e-1)" "unprognostic (1.43e-2)" "unprognostic (9.02e-2)" "unprognostic (4.04e-3)" "potential prognostic favorable (2.03e-7)" "unprognostic (1.84e-3)" "unprognostic (3.32e-1)" "potential prognostic favorable (1.15e-5)" "unprognostic (9.32e-3)" "unprognostic (1.14e-3)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (7.58e-3)" "unprognostic (1.38e-3)" "unprognostic (1.68e-1)" "unprognostic (3.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.61e-1)" "unprognostic (1.07e-2)" "unprognostic (3.90e-2)" "unprognostic (1.78e-1)" "unprognostic (1.60e-1)" HMGN2 HMG17 ENSG00000198830 "High mobility group nucleosomal binding domain 2" P05204 1 26472440-26476642 "Essential proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocyte progenitors: 245.1;Monocyte progenitors: 309.6;Neutrophil progenitors: 258.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 21176 "Macrophages: 1631823.6;T-cells: 2603465.0" "Tissue enhanced" "Detected in many" "ovary: 79419072.1" "CAB018371, HPA077364" Supported Supported Nucleoplasm,Nucleoli NA NA 3200000 "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 37 Nucleoplasm Nucleoli "CAB018371: , HPA077364: " "unprognostic (2.37e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-2)" "potential prognostic favorable (3.47e-5)" "unprognostic (2.47e-2)" "unprognostic (1.65e-1)" "unprognostic (2.87e-1)" "unprognostic (9.20e-3)" "unprognostic (2.71e-1)" "unprognostic (1.20e-2)" "potential prognostic favorable (3.08e-5)" "unprognostic (3.65e-2)" "unprognostic (3.83e-2)" "validated prognostic unfavorable (6.94e-5)" "validated prognostic unfavorable (7.37e-5)" "unprognostic (3.57e-2)" "unprognostic (6.82e-2)" "unprognostic (2.96e-2)" "unprognostic (1.31e-1)" "unprognostic (5.96e-2)" "unprognostic (1.54e-1)" "unprognostic (4.93e-2)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (1.10e-1)" "unprognostic (3.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.32e-1)" "unprognostic (1.30e-1)" "unprognostic (9.78e-2)" "unprognostic (7.82e-2)" HMGN5 NSBP1 ENSG00000198157 "High mobility group nucleosome binding domain 5" P82970 X 81113699-81201913 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 100.2" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 167.5;Epididymal principal cells: 213.7;Erythrocyte progenitors: 156.5;Sertoli cells: 409.5" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 409.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 707514.5;Granulosa cells: 815421.9" "Tissue enhanced" "Detected in many" "ovary: 39130818.1" "HPA000511, HPA076238" Approved Supported Nucleoplasm,Mitochondria NA NA 17000 "Cluster 24: Non-specific - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 117 Nucleoplasm Mitochondria "HPA000511: , HPA076238: " "unprognostic (1.35e-3)" "unprognostic (4.34e-3)" "unprognostic (8.16e-2)" "unprognostic (1.04e-1)" "unprognostic (1.85e-1)" "unprognostic (1.08e-1)" "unprognostic (7.70e-2)" "unprognostic (1.35e-1)" "unprognostic (9.83e-2)" "unprognostic (4.89e-2)" "unprognostic (2.90e-3)" "unprognostic (8.77e-2)" "unprognostic (4.20e-1)" "unprognostic (6.76e-2)" "unprognostic (2.40e-3)" "unprognostic (9.55e-2)" "unprognostic (1.23e-1)" "unprognostic (3.65e-1)" "unprognostic (8.99e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-1)" "unprognostic (4.27e-2)" "unprognostic (1.16e-2)" "unprognostic (8.13e-2)" "unprognostic (3.60e-3)" "unprognostic (1.26e-2)" "unprognostic (2.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-2)" "unprognostic (1.42e-1)" HMMR "CD168, RHAMM" ENSG00000072571 "Hyaluronan mediated motility receptor" O75330 5 163460203-163491941 "CD markers, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.4;lymphoid tissue: 25.4;testis: 25.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 51.0;Differentiating spermatogonia: 46.8;Early primary spermatocytes: 47.6;Early spermatids: 72.2;Enteric transient amplifying cells: 64.6;Erythrocyte progenitors: 127.5;Extravillous trophoblasts: 65.0;Late primary spermatocytes: 171.3;Late spermatids: 96.8;Megakaryocyte progenitors: 115.9;Migrating cytotrophoblasts: 57.5;Monocyte progenitors: 155.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 127.5;Megakaryocytes: 115.9;Mononuclear phagocytes: 155.5;Spermatogenic cell types: 171.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "T-reg: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2531 "Granulosa cells: 253070.0" "Tissue enriched" "Detected in single" 7133 "bone marrow: 713294.0" "CAB002433, HPA040025, HPA043926, HPA061524" Enhanced Enhanced Microtubules,Centrosome,Cytosol Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 27 Microtubules "Centrosome, Cytosol" "CAB002433: , HPA040025: , HPA043926: , HPA061524: " "unprognostic (3.14e-2)" "unprognostic (3.10e-2)" "unprognostic (6.94e-3)" "unprognostic (6.23e-2)" "unprognostic (1.54e-3)" "unprognostic (4.04e-1)" "unprognostic (1.12e-1)" "unprognostic (6.62e-2)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (1.83e-4)" "validated prognostic unfavorable (6.62e-6)" "validated prognostic unfavorable (1.22e-7)" "potential prognostic unfavorable (3.18e-7)" "validated prognostic unfavorable (4.04e-8)" "validated prognostic unfavorable (2.90e-10)" "validated prognostic unfavorable (8.47e-7)" "validated prognostic unfavorable (3.79e-4)" "unprognostic (6.08e-2)" "unprognostic (2.15e-1)" "unprognostic (2.23e-1)" "unprognostic (2.10e-1)" "validated prognostic unfavorable (6.82e-4)" "validated prognostic unfavorable (9.43e-4)" "unprognostic (3.38e-1)" "unprognostic (2.42e-2)" "unprognostic (1.77e-2)" "unprognostic (1.42e-1)" "unprognostic (5.82e-2)" "unprognostic (1.52e-1)" "unprognostic (4.72e-2)" HMOX2 HO-2 ENSG00000103415 "Heme oxygenase 2" P30519 16 4474690-4510347 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 2469.0" "Cell type enriched" "Detected in many" 9 "Spermatogenic cell types: 2469.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 52192707.6" "CAB025464, HPA040611" Supported Approved Vesicles,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 35: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 92 "Vesicles, Cytosol" "CAB025464: , HPA040611: " "unprognostic (2.20e-2)" "unprognostic (2.97e-3)" "unprognostic (2.12e-2)" "unprognostic (4.64e-2)" "unprognostic (3.12e-2)" "unprognostic (2.33e-1)" "unprognostic (7.62e-2)" "unprognostic (2.58e-3)" "unprognostic (2.20e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (8.87e-7)" "unprognostic (3.54e-2)" "unprognostic (7.17e-3)" "unprognostic (6.00e-2)" "unprognostic (1.98e-2)" "unprognostic (1.57e-1)" "unprognostic (3.13e-2)" "unprognostic (2.68e-1)" "unprognostic (4.25e-1)" "unprognostic (2.06e-1)" "unprognostic (9.56e-2)" "unprognostic (7.37e-3)" "unprognostic (3.54e-1)" "unprognostic (2.62e-1)" "unprognostic (2.28e-1)" "unprognostic (8.92e-2)" "unprognostic (3.12e-2)" "unprognostic (2.33e-1)" "unprognostic (2.85e-1)" "unprognostic (2.42e-1)" "unprognostic (1.70e-3)" HMX3 NKX5-1 ENSG00000188620 "H6 family homeobox 3" A6NHT5 10 123135970-123139423 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "brain: 4.5" "Cell type enriched" "Detected in some" 6 "Tuft cells: 34.6" "Cell type enriched" "Detected in some" 6 "Secretory gland support: 34.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "cervical cancer: 4.0;Leukemia: 5.8" "Colon - Colon enteroendocrine cells, Pituitary gland - Lactotropes" "Region enriched" "Detected in single" 4 "hypothalamus: 1.1" "Group enriched" "Detected in some" 5 "basal ganglia: 2.2;hypothalamus: 6.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA069659 Approved "Nucleoplasm,Centriolar satellite" Yes No "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" 1 Nucleoplasm "Centriolar satellite" "HPA069659: " "unprognostic (6.17e-2)" "unprognostic (5.79e-2)" "unprognostic (1.39e-1)" "unprognostic (4.93e-2)" HNF4A "HNF4, MODY, MODY1, NR2A1, TCF14" ENSG00000101076 "Hepatocyte nuclear factor 4 alpha" P41235 20 44355699-44432845 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 96.1;kidney: 42.7;liver: 112.7" "Cell type enhanced" "Detected in some" "Colonocytes: 443.6;Enteric stem cells: 432.7;Enteric transient amplifying cells: 348.2;Enterocytes: 333.4;Foveolar cells: 210.3;Gastric progenitor cells: 182.0;Goblet cells: 235.7;Hepatocytes: 281.9;Neuroendocrine cells: 168.2;Paneth cells: 355.8;Proximal tubule cells: 216.9;Tuft cells: 196.0" "Cell type enhanced" "Detected in many" "Enterocytes: 443.6;Goblet cells: 235.7;Hepatocytes: 281.9;Proliferating cells: 348.2;Secretory gland support: 355.8;Stem cells: 432.7" "Cell type enriched" "Detected in some" 30 "choroid plexus epithelial cell: 43.2" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 117.4;Rectum Adenocarcinoma (TCGA): 129.2" "Region enriched" "Detected in all" 10 "choroid plexus: 32.2" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "Bile duct cancer: 19.2;colorectal cancer: 57.4;Gastric cancer: 33.3;liver cancer: 41.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" "Hepatocytes: 1648222.6;Proximal tubules: 777252.4" "Group enriched" "Detected in some" 4817 "intestine: 707086.8;liver: 256383.4" "HPA004712, CAB019417" Enhanced Supported Nucleoplasm NA NA "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 38 Nucleoplasm "CAB019417: , HPA004712: " "unprognostic (1.77e-1)" "unprognostic (2.15e-1)" "unprognostic (2.31e-1)" "potential prognostic favorable (5.97e-7)" "unprognostic (1.61e-2)" "unprognostic (2.81e-2)" "unprognostic (4.61e-2)" "unprognostic (8.08e-2)" "unprognostic (1.52e-2)" "unprognostic (4.62e-2)" "unprognostic (1.68e-2)" "unprognostic (4.08e-3)" "unprognostic (2.41e-3)" "unprognostic (1.02e-2)" "unprognostic (1.40e-1)" "unprognostic (6.40e-3)" HNF4G NR2A2 ENSG00000164749 "Hepatocyte nuclear factor 4 gamma" Q14541 8 75407914-75566834 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "intestine: 108.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 210.7;Colonocytes: 272.8;Enteric stem cells: 253.4;Enteric transient amplifying cells: 264.9;Enterocytes: 771.5;Foveolar cells: 168.7;Goblet cells: 290.7;Neuroendocrine cells: 197.9;Pancreatic acinar cells: 190.9;Paneth cells: 375.1;Proximal tubule cells: 156.0;Tuft cells: 172.9" "Cell type enhanced" "Detected in many" "Enterocytes: 771.5;Goblet cells: 290.7;Proliferating cells: 264.9;Secretory gland support: 375.1" "Cell type enhanced" "Detected in many" "astrocyte: 79.3;Bergmann glia: 82.1;ependymal cell: 75.9;oligodendrocyte precursor cell: 42.8" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 17.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Gonadotropes, Prostate - Urothelial cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 379 "Proximal tubules: 37921.2" "Tissue enriched" "Detected in single" 3982 "intestine: 398175.7" "HPA005438, HPA010610" Enhanced Enhanced "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 Nucleoplasm "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA005438: , HPA010610: " "unprognostic (2.61e-1)" "unprognostic (1.98e-1)" "unprognostic (8.94e-2)" "unprognostic (1.26e-1)" "unprognostic (3.70e-2)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (7.30e-4)" "potential prognostic favorable (2.67e-8)" "unprognostic (2.79e-2)" "unprognostic (3.57e-2)" "unprognostic (1.17e-2)" "unprognostic (5.46e-2)" "unprognostic (3.31e-3)" "unprognostic (1.32e-3)" "unprognostic (4.74e-2)" "unprognostic (9.05e-3)" "unprognostic (1.60e-2)" "unprognostic (8.59e-2)" "unprognostic (8.27e-2)" "unprognostic (2.02e-2)" "unprognostic (5.36e-2)" "unprognostic (3.22e-2)" "unprognostic (2.42e-1)" "unprognostic (1.38e-1)" HNRNPA0 HNRPA0 ENSG00000177733 "Heterogeneous nuclear ribonucleoprotein A0" Q13151 5 137745651-137754363 "Plasma proteins, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 605.0;Migrating cytotrophoblasts: 472.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 137157901.2" "Low tissue specificity" "Detected in all" "HPA036569, HPA059404" Enhanced Enhanced Nucleoplasm No No 56000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 90 Nucleoplasm "HPA036569: , HPA059404: " "unprognostic (1.21e-1)" "unprognostic (1.54e-1)" "unprognostic (9.61e-2)" "unprognostic (2.08e-2)" "unprognostic (1.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (2.87e-1)" "unprognostic (2.75e-1)" "validated prognostic favorable (1.47e-6)" "validated prognostic favorable (3.88e-4)" "unprognostic (1.51e-1)" "unprognostic (1.16e-3)" "unprognostic (1.02e-3)" "unprognostic (8.05e-3)" "unprognostic (7.63e-2)" "unprognostic (4.08e-1)" "unprognostic (1.93e-2)" "unprognostic (3.26e-1)" "unprognostic (5.67e-2)" "unprognostic (1.34e-2)" "unprognostic (3.69e-1)" "unprognostic (5.32e-2)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (8.58e-2)" "unprognostic (5.40e-1)" "unprognostic (1.77e-1)" "unprognostic (2.01e-2)" "unprognostic (2.23e-2)" HNRNPC HNRPC ENSG00000092199 "Heterogeneous nuclear ribonucleoprotein C" P07910 14 21209136-21269494 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1730.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB005223, HPA051075, CAB075755, CAB075756, HPA078646" Supported Enhanced Nucleoplasm NA NA 1200000 "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 241 Nucleoplasm "CAB005223: , CAB075755: , CAB075756: , HPA051075: , HPA078646: " "potential prognostic unfavorable (1.23e-4)" "unprognostic (1.00e-1)" "unprognostic (2.25e-2)" "unprognostic (2.51e-2)" "unprognostic (1.60e-2)" "unprognostic (3.62e-1)" "unprognostic (3.66e-3)" "unprognostic (4.51e-2)" "unprognostic (1.40e-3)" "unprognostic (1.76e-2)" "potential prognostic favorable (3.13e-4)" "unprognostic (5.51e-2)" "unprognostic (7.47e-3)" "potential prognostic unfavorable (5.19e-5)" "unprognostic (1.66e-2)" "validated prognostic unfavorable (1.08e-5)" "validated prognostic unfavorable (6.00e-4)" "unprognostic (3.82e-2)" "unprognostic (1.48e-1)" "unprognostic (6.83e-2)" "unprognostic (3.11e-1)" "unprognostic (2.47e-3)" "unprognostic (2.13e-1)" "unprognostic (6.50e-2)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (8.16e-2)" "unprognostic (2.83e-1)" "unprognostic (2.66e-1)" "unprognostic (4.06e-2)" "unprognostic (6.85e-2)" HNRNPCL1 HNRPCL1 ENSG00000179172 "Heterogeneous nuclear ribonucleoprotein C like 1" O60812 1 12847377-12848720 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078646 Approved Nucleoplasm NA NA 32 Nucleoplasm "HPA078646: " HNRNPCL2 HNRNPCP5 ENSG00000275774 "Heterogeneous nuclear ribonucleoprotein C like 2" B2RXH8 1 13115488-13116854 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 2377 "Granulosa cells: 331875.5;T-cells: 143547.6" "Not detected" "Not detected" HPA078646 Approved Nucleoplasm NA NA "Cluster 53: Squamous epithelial cells - Keratinization" 17 Nucleoplasm "HPA078646: " HNRNPCL3 ENSG00000277058 "Heterogeneous nuclear ribonucleoprotein C like 3" B7ZW38 1 13060769-13062878 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078646 Approved Nucleoplasm NA NA "Cluster 59: Leukemia - T-cell receptor" 1 Nucleoplasm "HPA078646: " HNRNPCL4 ENSG00000179412 "Heterogeneous nuclear ribonucleoprotein C like 4" P0DMR1 1 13163914-13165631 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078646 Approved Nucleoplasm NA NA "Cluster 71: Lymphoma - Inflammatory response" Nucleoplasm "HPA078646: " HNRNPH1 "hnRNPH, HNRPH1" ENSG00000169045 "Heterogeneous nuclear ribonucleoprotein H1" P31943 5 179614178-179634784 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 366.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "bone marrow: 159620024.7" "HPA000914, HPA001359, HPA016884, CAB032820" Supported Enhanced Nucleoplasm NA NA 850000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 289 Nucleoplasm "CAB032820: , HPA000914: , HPA001359: , HPA016884: " "unprognostic (5.36e-2)" "unprognostic (4.53e-1)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (1.55e-2)" "unprognostic (3.88e-1)" "unprognostic (1.60e-1)" "unprognostic (1.77e-1)" "unprognostic (2.75e-3)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (1.90e-2)" "unprognostic (2.66e-3)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (7.08e-10)" "unprognostic (1.56e-1)" "unprognostic (1.39e-1)" "unprognostic (9.87e-2)" "unprognostic (2.74e-1)" "unprognostic (5.25e-2)" "unprognostic (1.51e-1)" "unprognostic (7.76e-2)" "unprognostic (1.75e-2)" "unprognostic (4.13e-3)" "unprognostic (1.00e-2)" "unprognostic (2.00e-3)" "unprognostic (1.27e-2)" "unprognostic (3.11e-2)" "unprognostic (2.41e-1)" "unprognostic (2.69e-1)" "unprognostic (3.54e-1)" "unprognostic (8.08e-2)" HNRNPH2 "FTP3, hnRNPH', HNRPH', HNRPH2" ENSG00000126945 "Heterogeneous nuclear ribonucleoprotein H2" P55795 X 101408222-101414133 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 184.4;Neutrophils: 202.2;Syncytiotrophoblasts: 389.1" "Cell type enhanced" "Detected in all" "Trophoblast cells: 389.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Neurons: 110179852.8" "Low tissue specificity" "Detected in all" "HPA000914, HPA001359, CAB004436, HPA016884" Supported Enhanced Nucleoplasm NA NA 380000 "Cluster 28: Neutrophils - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 42 Nucleoplasm "CAB004436: , HPA000914: , HPA001359: , HPA016884: " "unprognostic (1.23e-1)" "unprognostic (8.43e-2)" "unprognostic (1.48e-1)" "unprognostic (1.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (5.56e-2)" "unprognostic (1.38e-1)" "unprognostic (6.16e-2)" "unprognostic (1.05e-2)" "potential prognostic favorable (3.37e-6)" "unprognostic (1.18e-2)" "unprognostic (9.77e-2)" "unprognostic (2.01e-2)" "unprognostic (5.43e-2)" "unprognostic (1.39e-1)" "unprognostic (1.87e-2)" "unprognostic (2.08e-1)" "unprognostic (7.47e-2)" "unprognostic (1.29e-1)" "unprognostic (3.13e-2)" "unprognostic (5.67e-2)" "unprognostic (1.42e-1)" "unprognostic (1.37e-1)" "unprognostic (3.51e-1)" "unprognostic (3.89e-1)" "unprognostic (1.30e-1)" "unprognostic (1.47e-1)" "unprognostic (3.52e-2)" "unprognostic (3.40e-1)" "unprognostic (1.33e-1)" HNRNPLL HNRPLL ENSG00000143889 "Heterogeneous nuclear ribonucleoprotein L like" Q8WVV9 2 38561969-38603586 "Predicted intracellular proteins" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 222.9;Neutrophil progenitors: 529.9;Pituicytes/FSCs: 310.0" "Cell type enhanced" "Detected in all" "Glial cells: 310.0;Neutrophils: 529.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 26623211.4" "Low tissue specificity" "Detected in many" HPA046084 Approved Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 22 Nucleoplasm "Mitochondria, Cytosol" "HPA046084: " "unprognostic (1.64e-1)" "unprognostic (1.12e-1)" "unprognostic (6.67e-3)" "unprognostic (6.64e-2)" "unprognostic (1.52e-1)" "unprognostic (4.83e-2)" "unprognostic (1.23e-2)" "unprognostic (3.44e-1)" "unprognostic (7.57e-3)" "potential prognostic favorable (3.92e-4)" "unprognostic (5.86e-2)" "unprognostic (3.88e-1)" "potential prognostic unfavorable (5.49e-5)" "unprognostic (8.78e-2)" "unprognostic (6.14e-2)" "unprognostic (2.65e-1)" "unprognostic (3.76e-1)" "unprognostic (7.79e-2)" "unprognostic (5.41e-3)" "unprognostic (3.42e-2)" "unprognostic (1.76e-3)" "unprognostic (3.93e-3)" "unprognostic (1.57e-1)" "unprognostic (1.86e-3)" "unprognostic (9.22e-2)" "unprognostic (2.67e-1)" "unprognostic (8.52e-3)" "unprognostic (1.37e-1)" "unprognostic (8.17e-2)" HOMER1 "HOMER-1B, SYN47, Ves-1" ENSG00000152413 "Homer scaffold protein 1" Q86YM7 5 79372636-79514134 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.6;skeletal muscle: 31.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 934.7;Salivary myoepithelial cells: 595.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 934.7;Secretory gland support: 595.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 18144402.6;Microglia and Neuropil: 30310368.7;Neurons: 45219502.7" "Tissue enriched" "Detected in some" "cerebral cortex: 73780615.9" "CAB004437, HPA036521, HPA036522" Enhanced Supported Approved Cytosol No No "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 42 Cytosol "CAB004437: , HPA036521: , HPA036522: " "unprognostic (1.42e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (9.11e-2)" "unprognostic (4.63e-2)" "unprognostic (7.39e-2)" "unprognostic (2.84e-1)" "unprognostic (1.93e-1)" "unprognostic (1.56e-1)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (6.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (9.57e-3)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (8.29e-3)" "unprognostic (9.57e-2)" "unprognostic (2.37e-1)" "unprognostic (5.80e-2)" "unprognostic (1.46e-3)" "unprognostic (9.38e-2)" "unprognostic (1.05e-1)" "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (4.51e-1)" "unprognostic (5.93e-2)" "unprognostic (1.66e-1)" "unprognostic (2.70e-2)" "unprognostic (2.53e-1)" HORMAD1 "CT46, DKFZP434A1315" ENSG00000143452 "HORMA domain containing 1" Q86X24 1 150698060-150720895 "Predicted intracellular proteins" "Differentiation, Meiosis, Oogenesis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 110.1" "Group enriched" "Detected in many" 4 "Early primary spermatocytes: 771.5;Late primary spermatocytes: 549.3" "Cell type enriched" "Detected in many" 24 "Spermatogenic cell types: 771.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 12.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 18.2" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA028346, HPA037850" Enhanced Approved Nucleoplasm,Nucleoli Yes No "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 Nucleoplasm Nucleoli "HPA028346: , HPA037850: " "unprognostic (9.82e-2)" "unprognostic (1.94e-2)" "unprognostic (1.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.42e-3)" "unprognostic (4.17e-2)" "unprognostic (2.18e-1)" "unprognostic (2.22e-2)" "unprognostic (1.20e-1)" "unprognostic (8.18e-2)" "unprognostic (7.94e-2)" "unprognostic (6.40e-2)" "unprognostic (2.37e-2)" "unprognostic (2.18e-1)" HORMAD2 "CT46.2, MGC26710" ENSG00000176635 "HORMA domain containing 2" Q8N7B1 22 30080464-30177075 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 21.3" "Group enriched" "Detected in some" 4 "Early primary spermatocytes: 237.4;Late primary spermatocytes: 176.1" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 237.4" "Group enriched" "Detected in some" 6 "astrocyte: 9.0;Bergmann glia: 9.8;ependymal cell: 3.5;oligodendrocyte precursor cell: 3.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003074, HPA043880" Enhanced Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 65: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 4 Nucleoplasm "Centrosome, Cytosol" "HPA003074: , HPA043880: " "potential prognostic unfavorable (3.27e-4)" HOXA11 "HOX1, HOX1I" ENSG00000005073 "Homeobox A11" P31270 7 27181157-27185232 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 52.4;endometrium 1: 80.2;smooth muscle: 38.5" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 9.6;Decidual stromal cells: 31.1;Endometrial stromal cells: 97.2;Prostatic club cells: 18.4;Prostatic hillock cells: 12.5;Smooth muscle cells: 9.4;Tuft cells: 11.5" "Cell type enriched" "Detected in some" 5 "Stromal cells: 97.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in single" 56 "spinal cord: 5.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006770, HPA035623" Enhanced Supported Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 108: Fibroblasts - ECM organization" 3 Nucleoplasm "HPA006770: , HPA035623: " "unprognostic (7.48e-2)" "unprognostic (2.16e-1)" "unprognostic (9.40e-2)" "unprognostic (9.67e-2)" "unprognostic (2.04e-2)" "unprognostic (4.27e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (7.46e-5)" "unprognostic (5.03e-3)" "unprognostic (1.54e-1)" "unprognostic (1.29e-3)" "unprognostic (1.64e-1)" "unprognostic (3.63e-1)" "unprognostic (3.74e-3)" "unprognostic (2.22e-1)" "unprognostic (1.97e-1)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (8.08e-4)" "potential prognostic unfavorable (7.65e-5)" "unprognostic (3.28e-2)" "unprognostic (9.82e-2)" "unprognostic (4.33e-2)" HOXA13 "HOX1, HOX1J" ENSG00000106031 "Homeobox A13" P31271 7 27193503-27200091 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 21.0;placenta: 16.0;prostate: 20.9;seminal vesicle: 21.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 26.5;Colonocytes: 37.9;Enteric stem cells: 11.8;Enteric transient amplifying cells: 11.4;Gastric progenitor cells: 21.8;Goblet cells: 9.5;Prostatic club cells: 44.5;Prostatic glandular cells: 36.4;Prostatic hillock cells: 44.9;Smooth muscle cells: 13.2;Tuft cells: 23.1;Urothelial cells: 8.5" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 44.9;Basal cells: 26.5;Enterocytes: 37.9;Glandular cells: 44.5;Proliferating cells: 21.8;Secretory gland support: 23.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046098, HPA069061" Supported "Nucleoplasm,Mitotic chromosome,Intermediate filaments" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Nucleoplasm "Mitotic chromosome, Intermediate filaments" "HPA046098: , HPA069061: " "unprognostic (2.65e-2)" "unprognostic (3.30e-1)" "unprognostic (6.36e-2)" "unprognostic (1.46e-1)" "unprognostic (1.23e-3)" "unprognostic (1.79e-1)" "unprognostic (3.06e-1)" "unprognostic (2.35e-1)" "unprognostic (2.84e-1)" "unprognostic (1.01e-2)" "unprognostic (2.97e-2)" "unprognostic (3.50e-1)" "unprognostic (1.19e-1)" "unprognostic (2.48e-3)" "unprognostic (3.33e-3)" "unprognostic (1.64e-1)" HOXA2 HOX1K ENSG00000105996 "Homeobox A2" O43364 7 27100354-27102686 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 4.3;Epididymal basal cells: 5.0;Epididymal clear cells: 4.1;Epididymal efferent duct absorptive cells: 15.6;Epididymal efferent duct ciliated cells: 5.9;Esophageal basal cells: 4.2;Medullary thymic epithelial cells: 4.8;Mesothelial cells: 4.2;Submucosal glandular cells: 3.7;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "Ductal cells: 15.6;Secretory gland support: 11.5" "Cell type enhanced" "Detected in some" "ependymal cell: 3.1;lower rhombic lip: 3.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 22 "medulla oblongata: 9.7;pons: 6.5;spinal cord: 10.2;white matter: 8.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 36 "pons and medulla: 5.8" "Region enhanced" "Detected in some" "medulla oblongata: 9.5;spinal cord: 10.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA078220 Approved Nucleoplasm,Vesicles Yes NA "Cluster 22: Epididymis - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 1 "Nucleoplasm, Vesicles" "HPA078220: " "unprognostic (4.68e-2)" "unprognostic (6.43e-2)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (8.47e-2)" "potential prognostic unfavorable (6.26e-4)" "potential prognostic unfavorable (8.31e-8)" "unprognostic (2.43e-1)" "unprognostic (5.47e-3)" "unprognostic (1.69e-2)" "unprognostic (1.20e-1)" "unprognostic (8.87e-2)" "unprognostic (4.84e-3)" "unprognostic (5.20e-3)" "unprognostic (1.04e-1)" "unprognostic (2.67e-1)" HOXA9 "HOX1, HOX1G" ENSG00000078399 "Homeobox A9" P31269 7 27162438-27175180 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 27.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 35.8;Enteric stem cells: 26.1;Epididymal principal cells: 36.8;Goblet cells: 24.5;Hematopoietic stem cells: 50.9;Innate lymphoid cells: 25.9;Megakaryocyte-Erythroid progenitors: 22.2;Neuroendocrine cells: 24.8;Podocytes: 29.7;Prostatic club cells: 38.2;Prostatic hillock cells: 34.7;Renal connecting tubule cells: 27.8;Thymocytes: 22.0" "Cell type enhanced" "Detected in many" "Stem cells: 50.9" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 6.7;myeloid DC: 5.6;NK-cell: 11.6" "Group enriched" "Detected in many" 6 "dendritic cells: 5.6;granulocytes: 6.7;NK-cells: 11.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 56.5;Kidney cancer: 53.0" "Not detected" "Not detected" "Region enriched" "Detected in single" 191 "spinal cord: 19.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA061982, HPA076200" Uncertain Enhanced Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 Nucleoplasm "HPA061982: , HPA076200: " "unprognostic (3.28e-2)" "unprognostic (2.50e-1)" "unprognostic (2.62e-3)" "unprognostic (1.15e-2)" "unprognostic (1.59e-1)" "unprognostic (7.84e-2)" "unprognostic (1.61e-1)" "unprognostic (1.22e-1)" "unprognostic (1.05e-1)" "unprognostic (3.16e-1)" "unprognostic (2.80e-2)" "unprognostic (9.40e-2)" "unprognostic (1.58e-2)" "unprognostic (3.18e-3)" "unprognostic (2.74e-1)" "unprognostic (1.34e-3)" "unprognostic (3.04e-2)" "unprognostic (2.80e-1)" "unprognostic (8.24e-3)" "unprognostic (1.76e-1)" "unprognostic (5.69e-2)" "unprognostic (9.72e-2)" HOXB13 ENSG00000159184 "Homeobox B13" Q92826 17 48724763-48728750 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "intestine: 38.7;prostate: 77.3" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 26.5;Colonocytes: 140.1;Enteric stem cells: 57.5;Enteric transient amplifying cells: 54.0;Goblet cells: 64.3;Neuroendocrine cells: 64.4;Prostatic club cells: 25.4;Prostatic glandular cells: 138.5" "Cell type enhanced" "Detected in some" "Enterocytes: 140.1;Enteroendocrine cells: 64.4;Glandular cells: 138.5;Goblet cells: 64.3;Proliferating cells: 54.0;Stem cells: 57.5" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 11 "Prostate Adenocarcinoma (TCGA): 297.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "prostate cancer: 151.6" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004438, HPA062852, HPA065019" Enhanced Enhanced Nucleoplasm NA NA "Cluster 38: Non-specific - Basic cellular processes" "Cluster 60: Prostate cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Nucleoplasm "CAB004438: , HPA062852: , HPA065019: " "potential prognostic unfavorable (7.48e-4)" "unprognostic (3.68e-2)" "unprognostic (2.17e-1)" "unprognostic (1.03e-1)" "unprognostic (7.60e-2)" "unprognostic (8.17e-3)" "unprognostic (6.37e-3)" "unprognostic (2.01e-3)" "unprognostic (2.51e-2)" "unprognostic (1.61e-2)" "unprognostic (4.74e-2)" "unprognostic (2.54e-1)" "unprognostic (2.83e-2)" "unprognostic (2.08e-1)" "unprognostic (1.30e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (2.79e-2)" "unprognostic (1.50e-3)" "unprognostic (4.63e-2)" "unprognostic (7.31e-2)" "unprognostic (6.25e-2)" HOXB9 "HOX2, HOX2E" ENSG00000170689 "Homeobox B9" P17482 17 48621156-48626358 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 83.0;intestine: 24.7;kidney: 22.0" "Group enriched" "Detected in some" 4 "Endometrial secretory cells: 6.8;Epididymal basal cells: 9.7;Epididymal clear cells: 4.1;Epididymal efferent duct absorptive cells: 9.3;Epididymal efferent duct ciliated cells: 3.8;Epididymal principal cells: 11.7;Neuroendocrine cells: 6.3;Tuft cells: 11.5" "Cell type enhanced" "Detected in some" "Basal cells: 9.7;Ductal cells: 9.3;Enteroendocrine cells: 6.3;Reproductive supporting cells: 11.7;Secretory cells: 6.8;Secretory gland support: 11.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 80.5;Rectum Adenocarcinoma (TCGA): 68.6" "Group enriched" "Detected in some" 15 "spinal cord: 6.1;white matter: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 64.6" "Colon - Colon enterocytes" "Not detected" "Not detected" "Region enriched" "Detected in single" 190 "spinal cord: 19.0" "Cell type enriched" "Detected in single" 2506 "Collecting ducts: 250628.2" "Not detected" "Not detected" HPA004928 Supported Nucleoplasm NA No "Cluster 22: Epididymis - Mixed function" "Cluster 22: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 95: Tuft cells - Chemosensory signaling" 54 Nucleoplasm "HPA004928: " "unprognostic (3.00e-2)" "unprognostic (1.54e-1)" "unprognostic (4.19e-2)" "unprognostic (2.69e-1)" "unprognostic (1.26e-1)" "unprognostic (5.56e-2)" "potential prognostic unfavorable (2.39e-5)" "unprognostic (6.07e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (4.78e-3)" "unprognostic (5.63e-2)" "potential prognostic unfavorable (8.90e-4)" "unprognostic (2.08e-1)" "unprognostic (2.54e-2)" "unprognostic (2.46e-1)" "unprognostic (1.29e-2)" "unprognostic (1.65e-1)" "unprognostic (1.90e-3)" "unprognostic (5.94e-2)" "unprognostic (3.78e-1)" "unprognostic (7.73e-2)" "unprognostic (4.29e-3)" "unprognostic (8.98e-2)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (3.24e-4)" HOXC6 "HOX3, HOX3C" ENSG00000197757 "Homeobox C6" P09630 12 53990624-54030823 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 31.0" "Cell type enhanced" "Detected in single" "Smooth muscle cells: 3.2" "Cell type enhanced" "Detected in single" "Smooth muscle cells: 3.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 11 "medulla oblongata: 6.9;pons: 9.4;spinal cord: 6.7;white matter: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 41.4" "Breast - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2" "Region enriched" "Detected in single" 15 "pons and medulla: 1.4" "Region enriched" "Detected in some" 15 "spinal cord: 14.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA054981 Supported Nucleoplasm,Cytosol No No "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" Nucleoplasm Cytosol "HPA054981: " "unprognostic (2.51e-2)" "unprognostic (1.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.33e-1)" "unprognostic (1.35e-3)" "unprognostic (1.32e-3)" "unprognostic (3.55e-3)" "potential prognostic unfavorable (8.84e-5)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (2.27e-2)" "unprognostic (2.18e-2)" "unprognostic (8.97e-2)" "unprognostic (4.58e-2)" "unprognostic (7.53e-3)" "unprognostic (3.43e-1)" "unprognostic (2.36e-2)" "unprognostic (1.69e-1)" "unprognostic (1.51e-2)" "unprognostic (8.95e-3)" "unprognostic (1.28e-1)" "unprognostic (8.44e-3)" "unprognostic (4.24e-2)" "unprognostic (9.81e-3)" "unprognostic (1.14e-1)" "unprognostic (1.14e-1)" "unprognostic (2.06e-1)" "unprognostic (1.24e-1)" "unprognostic (1.32e-1)" HOXD10 "HOX4, HOX4D" ENSG00000128710 "Homeobox D10" P28358 2 176108790-176119937 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 20.7;endometrium 1: 38.4;kidney: 24.2;vagina: 24.8" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 77.9;Colonocytes: 35.3;Decidual stromal cells: 68.0;Distal convoluted tubule cells: 95.1;Endometrial stromal cells: 50.9;Loop of henle epithelial cells: 56.0;Lymphatic endothelial cells: 27.7;Neuroendocrine cells: 38.8;Papillary tip epithelial cells: 36.8;Prostatic club cells: 27.5;Prostatic hillock cells: 33.4;Renal collecting duct principal cells: 96.0;Renal connecting tubule cells: 124.3" "Cell type enhanced" "Detected in many" "Basal cells: 77.9;Ductal cells: 124.3;Renal nephron cells: 95.1;Stromal cells: 68.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 27.6;Gallbladder cancer: 24.8" "Not detected" "Not detected" "Region enriched" "Detected in single" 67 "spinal cord: 6.6" "Group enriched" "Detected in some" 2422 "Collecting ducts: 301403.5;Distal tubules: 183060.3" "Not detected" "Not detected" HPA065871 Approved "Nucleoplasm,Cytosol,Cytoplasmic bodies" No NA "Cluster 75: Ovary - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 105: Non-specific - Mixed function" 9 Nucleoplasm "Cytosol, Cytoplasmic bodies" "HPA065871: " "unprognostic (5.60e-2)" "unprognostic (1.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.34e-1)" "unprognostic (4.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.96e-2)" "unprognostic (4.86e-3)" "unprognostic (1.21e-1)" "unprognostic (2.37e-1)" "unprognostic (2.41e-2)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (1.93e-1)" "unprognostic (1.36e-1)" "unprognostic (2.99e-1)" "unprognostic (6.11e-2)" "unprognostic (2.71e-1)" "unprognostic (1.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.23e-2)" HPDL "4-HPPD-L, GLOXD1, MGC15668" ENSG00000186603 "4-hydroxyphenylpyruvate dioxygenase like" Q96IR7 1 45326895-45328710 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 42.4;Enteric stem cells: 19.0;Enteric transient amplifying cells: 14.9;Erythrocyte progenitors: 11.4;Esophageal basal cells: 8.0;Gastric progenitor cells: 23.1;Megakaryocyte progenitors: 13.2;Megakaryocyte-Erythroid progenitors: 9.1;Megakaryocytes: 12.4;Migrating cytotrophoblasts: 34.4;Paneth cells: 11.6" "Cell type enhanced" "Detected in many" "Proliferating cells: 23.1;Stem cells: 19.0;Trophoblast cells: 42.4" "Cell type enhanced" "Detected in some" "astrocyte: 3.0;upper rhombic lip: 2.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Distal tubules: 185688.7" "Tissue enriched" "Detected in single" 4191 "intestine: 419147.9" "HPA031997, HPA057346" Supported Nucleoplasm,Mitochondria No NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Mitochondria Nucleoplasm "HPA031997: , HPA057346: " "unprognostic (2.10e-2)" "unprognostic (2.51e-3)" "unprognostic (1.29e-1)" "unprognostic (8.84e-2)" "unprognostic (1.69e-1)" "unprognostic (6.30e-2)" "unprognostic (1.45e-1)" "unprognostic (5.90e-2)" "unprognostic (1.21e-1)" "unprognostic (1.36e-1)" "unprognostic (2.63e-3)" "unprognostic (1.79e-2)" "potential prognostic unfavorable (7.76e-4)" "unprognostic (1.02e-1)" "unprognostic (1.27e-1)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (6.21e-2)" "unprognostic (1.14e-1)" "unprognostic (3.32e-2)" "unprognostic (2.69e-1)" HPF1 "C4orf27, FLJ20534" ENSG00000056050 "Histone PARylation factor 1" Q9NWY4 4 169729470-169757944 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 303.9" "Cell type enhanced" "Detected in all" "Oocytes: 303.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 27097764.2" "Low tissue specificity" "Detected in many" HPA043467 Uncertain Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 7 Cytosol "Microtubules, Cytokinetic bridge" "HPA043467: " "unprognostic (4.32e-2)" "unprognostic (3.50e-3)" "unprognostic (1.70e-2)" "unprognostic (2.75e-2)" "unprognostic (2.01e-3)" "unprognostic (3.78e-3)" "unprognostic (6.23e-2)" "unprognostic (3.31e-1)" "unprognostic (4.84e-2)" "potential prognostic favorable (1.36e-5)" "unprognostic (2.95e-2)" "unprognostic (3.73e-1)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (9.43e-2)" "unprognostic (8.35e-2)" "unprognostic (1.17e-1)" "unprognostic (2.71e-2)" "unprognostic (2.53e-1)" "unprognostic (1.55e-1)" "unprognostic (5.26e-2)" "unprognostic (3.71e-1)" "unprognostic (1.87e-2)" "unprognostic (3.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.32e-1)" "unprognostic (2.54e-1)" "unprognostic (3.76e-3)" "unprognostic (4.89e-2)" HPGD SDR36C1 ENSG00000164120 "15-hydroxyprostaglandin dehydrogenase" P15428 4 174490175-174523154 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Prostaglandin metabolism" Oxidoreductase "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 222.0;urinary bladder: 352.4" "Cell type enhanced" "Detected in many" "Enterocytes: 600.7;Esophageal apical cells: 2508.6;Extravillous trophoblasts: 1375.4;Foveolar cells: 1121.8;Mast cells: 1378.9;Neutrophils: 640.0;Prostatic club cells: 638.1;Prostatic hillock cells: 401.8;Urothelial cells: 1575.5" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 2508.6;Barrier epithelial cells: 1575.5;Gastric glandular cells: 1121.8;Mast cells: 1378.9;Trophoblast cells: 1375.4" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 85.5;endothelial cell: 47.0" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 97.6" "Region enhanced" "Detected in many" "choroid plexus: 17.4" "Group enriched" "Detected in many" 5 "basophil: 123.8;T-reg: 45.1" "Group enriched" "Detected in many" 73 "granulocytes: 123.8;T-cells: 45.1" "Cancer enhanced" "Detected in many" "testis cancer: 111.7" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 32942187.2;Hepatocytes: 22447456.5;Proximal tubules: 15856449.5" "Tissue enhanced" "Detected in many" "liver: 15784966.6;lung: 12890350.6" "HPA004919, HPA005679" Enhanced Supported Nucleoplasm,Cytosol No NA 12000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 69: Urothelial cells - Basic cellular functions" 4 Cytosol Nucleoplasm "HPA004919: , HPA005679: " "unprognostic (2.13e-1)" "unprognostic (8.70e-3)" "unprognostic (3.55e-1)" "unprognostic (2.22e-1)" "unprognostic (3.68e-2)" "unprognostic (1.01e-1)" "unprognostic (4.47e-1)" "unprognostic (4.01e-2)" "unprognostic (1.59e-1)" "potential prognostic favorable (9.77e-8)" "unprognostic (6.86e-3)" "unprognostic (5.76e-3)" "unprognostic (1.19e-1)" "unprognostic (5.71e-3)" "unprognostic (3.76e-1)" "unprognostic (3.10e-1)" "unprognostic (2.63e-1)" "unprognostic (2.77e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (3.95e-3)" "unprognostic (6.02e-3)" "unprognostic (8.05e-3)" "unprognostic (2.18e-1)" "unprognostic (3.50e-1)" "unprognostic (6.74e-2)" "unprognostic (1.26e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (1.33e-5)" "unprognostic (4.72e-1)" HPS3 "BLOC2S1, SUTAL" ENSG00000163755 "HPS3 biogenesis of lysosomal organelles complex 2 subunit 1" Q969F9 3 149129638-149173732 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 159.9" "Cell type enhanced" "Detected in all" "Glial cells: 159.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 204.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 1018722.4" "Tissue enhanced" "Detected in some" "intestine: 732137.2" "HPA046281, HPA052778" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 4 "Golgi apparatus, Plasma membrane" "HPA046281: , HPA052778: " "unprognostic (9.92e-2)" "unprognostic (1.37e-2)" "unprognostic (3.05e-2)" "unprognostic (3.00e-2)" "unprognostic (1.01e-1)" "unprognostic (2.20e-2)" "unprognostic (1.30e-1)" "unprognostic (5.15e-2)" "unprognostic (3.54e-1)" "unprognostic (1.17e-3)" "potential prognostic favorable (6.31e-5)" "unprognostic (3.30e-2)" "unprognostic (1.63e-1)" "unprognostic (2.16e-2)" "unprognostic (9.24e-2)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (1.18e-2)" "unprognostic (2.25e-1)" "unprognostic (1.66e-1)" "unprognostic (2.54e-1)" "unprognostic (4.10e-2)" "unprognostic (7.97e-3)" "unprognostic (2.22e-3)" "unprognostic (2.25e-1)" "unprognostic (4.34e-2)" "unprognostic (5.26e-3)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (1.57e-1)" "unprognostic (9.26e-2)" "unprognostic (4.70e-2)" HPSE "HPA, HPSE1, HSE1" ENSG00000173083 Heparanase Q9Y251 4 83292461-83335153 "Enzymes, Metabolic proteins, Predicted secreted proteins" "Cell adhesion" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 88.7;Esophageal apical cells: 314.7;Kupffer cells: 63.5;monocytes: 58.0;Neutrophils: 150.3;Platelets: 242.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 314.7;Neutrophils: 150.3;Platelets: 242.0" "Cell type enriched" "Detected in some" 7 "central nervous system macrophage: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.2;neutrophil: 18.6" "Group enriched" "Detected in many" 4 "granulocytes: 18.6;monocytes: 27.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Macrophages, Heart muscle - Macrophages" "Region enhanced" "Detected in some" "olfactory bulb: 3.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1040 "Keratinocytes: 103959.7" "Group enriched" "Detected in many" "bone marrow: 60752123.4;lymphoid tissue: 54736271.8" "CAB009813, HPA055344" Supported Nucleoplasm,Vesicles "Secreted to extracellular matrix" "Cell adhesion" No No 8900000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" 5 Nucleoplasm Vesicles "CAB009813: , HPA055344: " "unprognostic (1.21e-3)" "unprognostic (1.49e-2)" "unprognostic (7.80e-2)" "unprognostic (1.68e-3)" "unprognostic (1.37e-1)" "unprognostic (2.95e-2)" "unprognostic (3.00e-1)" "unprognostic (4.48e-2)" "unprognostic (2.83e-1)" "unprognostic (4.26e-2)" "unprognostic (1.85e-2)" "unprognostic (2.77e-1)" "unprognostic (3.37e-1)" "unprognostic (9.39e-2)" "unprognostic (5.24e-3)" "unprognostic (1.06e-2)" "unprognostic (7.15e-2)" "unprognostic (8.66e-2)" "unprognostic (2.45e-1)" "unprognostic (2.85e-1)" "unprognostic (1.55e-2)" "unprognostic (2.84e-1)" "unprognostic (2.65e-1)" "unprognostic (1.30e-1)" "unprognostic (4.67e-2)" "unprognostic (8.85e-2)" "unprognostic (3.85e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (6.82e-4)" HRC MGC133236 ENSG00000130528 "Histidine rich calcium binding protein" P23327 19 49151198-49155396 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 26 "heart muscle: 692.1;skeletal muscle: 424.2;tongue: 228.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 50.1;Hepatic stellate cells: 19.4;Myonuclei: 74.9;Oocytes: 36.8;Pericytes: 39.3;Thymic myoid cells: 142.8;Vascular smooth muscle cells: 45.6" "Cell type enhanced" "Detected in many" "Mural cells: 45.6;Myocytes: 74.9;Oocytes: 36.8;Stromal cells: 142.8" "Group enriched" "Detected in some" 13 "pericyte: 25.1;vascular associated smooth muscle cell: 21.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Myeloma: 7.7;Rhabdoid: 2.9;Sarcoma: 5.7" "Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Liver - Hepatic stellate cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" "Capillaries: 182261466.3;Cardiomyocytes: 283772405.4;Skeletal myofibers: 94386885.4" "Tissue enriched" "Detected in many" "heart muscle: 545669819.0" "HPA004833, HPA004834" Enhanced Supported "Endoplasmic reticulum,Mitochondria,Cytosol" "Intracellular and membrane" "No annotated function" NA NA 170000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 110: Mural cells - ECM organization" 2 "Endoplasmic reticulum" "Mitochondria, Cytosol" "HPA004833: , HPA004834: " "unprognostic (7.68e-2)" "unprognostic (5.50e-2)" "unprognostic (9.55e-3)" "unprognostic (2.97e-2)" "unprognostic (4.19e-1)" "unprognostic (1.37e-1)" "unprognostic (1.46e-2)" "unprognostic (2.62e-1)" "validated prognostic favorable (3.54e-4)" "validated prognostic favorable (3.47e-6)" "unprognostic (3.31e-3)" "unprognostic (9.09e-2)" "unprognostic (2.81e-2)" "unprognostic (1.37e-1)" "unprognostic (7.89e-2)" "unprognostic (1.25e-1)" "unprognostic (4.76e-2)" HRNR "FLG3, S100A16, S100a18" ENSG00000197915 Hornerin Q86YZ3 1 152212076-152224193 "Plasma proteins, Predicted intracellular proteins" Keratinization "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Adipocytes: 5.2;Cardiomyocytes: 15.5;Epicardial cells: 25.0;Fibro-adipogenic progenitors: 5.3;Retinal ganglion cells: 3.9" "Cell type enhanced" "Detected in some" "Barrier epithelial cells: 25.0;Myocytes: 15.5" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in single" "Skin Cutaneous Melanoma (TCGA): 2.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.0" "Not detected" "Not detected" "Group enriched" "Detected in some" "Microglia and Neuropil: 1500586.2;T-cells: 663866.0" "Tissue enhanced" "Detected in all" "intestine: 1968999031.5" HPA031469 Uncertain Uncertain Mitochondria No No 660000000 "Cluster 49: Hindbrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 10 Mitochondria "HPA031469: " "unprognostic (1.28e-1)" HS1BP3 HS1-BP3,FLJ14249 ENSG00000118960 "HCLS1 binding protein 3" Q53T59 2 20560448-20651130 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 73.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA035050 Approved Approved Nucleoli,Cytosol No No 21000 "Cluster 7: Non-specific - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 12 Nucleoli Cytosol "HPA035050: " "unprognostic (2.01e-2)" "unprognostic (1.89e-2)" "unprognostic (1.42e-1)" "unprognostic (2.20e-2)" "unprognostic (1.11e-1)" "unprognostic (3.47e-2)" "unprognostic (2.45e-2)" "unprognostic (8.61e-2)" "unprognostic (2.03e-2)" "unprognostic (1.66e-1)" "potential prognostic favorable (4.61e-11)" "unprognostic (2.17e-1)" "unprognostic (1.75e-2)" "unprognostic (1.98e-3)" "unprognostic (6.97e-3)" "unprognostic (8.18e-2)" "unprognostic (1.77e-1)" "unprognostic (2.98e-1)" "unprognostic (1.58e-1)" "unprognostic (7.70e-2)" "unprognostic (3.86e-1)" "unprognostic (2.69e-1)" "unprognostic (3.19e-2)" "unprognostic (3.57e-1)" "unprognostic (1.91e-1)" "unprognostic (1.97e-3)" "unprognostic (2.61e-1)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (4.78e-2)" "unprognostic (2.82e-1)" HS2ST1 KIAA0448 ENSG00000153936 "Heparan sulfate 2-O-sulfotransferase 1" Q7LGA3 1 86914635-87109982 "Disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 315.9;Astrocytes: 241.8;Choroid plexus epithelial cells: 279.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 315.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 5177258.0;Pancreatic islets: 4853977.4" "Tissue enhanced" "Detected in many" "intestine: 2235925.2;lymphoid tissue: 2444940.5" "HPA043069, HPA043603, HPA075001" Supported Approved Mitochondria No No "Cluster 34: B-cells - Unknown function" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 Mitochondria "HPA043069: , HPA043603: , HPA075001: " "unprognostic (2.12e-2)" "unprognostic (1.17e-1)" "unprognostic (3.27e-1)" "unprognostic (3.15e-1)" "unprognostic (1.01e-3)" "unprognostic (1.12e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (9.17e-4)" "unprognostic (5.05e-2)" "potential prognostic unfavorable (3.78e-4)" "potential prognostic favorable (4.65e-7)" "unprognostic (3.84e-3)" "unprognostic (7.14e-2)" "unprognostic (7.71e-3)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (3.51e-2)" "unprognostic (2.12e-1)" "unprognostic (2.45e-1)" "unprognostic (2.44e-1)" "unprognostic (6.14e-3)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (1.36e-3)" "unprognostic (3.13e-1)" "unprognostic (1.94e-1)" "unprognostic (2.44e-2)" "unprognostic (2.09e-2)" "unprognostic (4.79e-2)" "unprognostic (2.91e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" HS6ST1 HS6ST ENSG00000136720 "Heparan sulfate 6-O-sulfotransferase 1" O60243 2 128236716-128318868 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 159.4;Mast cells: 213.3;Renal collecting duct principal cells: 242.1" "Cell type enhanced" "Detected in many" "Ductal cells: 242.1;Mast cells: 213.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1300379.4;Pancreatic islets: 1134649.3" "Tissue enriched" "Detected in single" 2382 "cerebral cortex: 238215.4" HPA044586 Approved Nucleoplasm NA NA 260000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 58: Mast cells - Allergic inflammatory responses" 6 Nucleoplasm "HPA044586: " "unprognostic (2.45e-1)" "unprognostic (6.34e-2)" "unprognostic (2.47e-1)" "unprognostic (3.37e-1)" "unprognostic (3.72e-1)" "unprognostic (2.76e-1)" "unprognostic (4.63e-2)" "unprognostic (6.50e-2)" "unprognostic (3.63e-1)" "unprognostic (2.20e-1)" "potential prognostic favorable (7.03e-5)" "unprognostic (3.02e-2)" "unprognostic (5.18e-2)" "unprognostic (2.39e-2)" "unprognostic (2.86e-3)" "unprognostic (1.27e-2)" "unprognostic (5.15e-2)" "unprognostic (6.64e-2)" "unprognostic (8.58e-2)" "unprognostic (9.68e-2)" "unprognostic (3.75e-1)" "unprognostic (1.62e-1)" "unprognostic (1.97e-1)" "unprognostic (2.19e-1)" "unprognostic (3.46e-1)" "unprognostic (8.60e-3)" "unprognostic (1.77e-1)" "unprognostic (5.27e-2)" "unprognostic (1.66e-1)" "unprognostic (7.04e-3)" "unprognostic (2.73e-1)" HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 6.1;brain: 16.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1361.5;Bergmann glia: 1233.3;Brain excitatory neurons: 1266.9;Brain inhibitory neurons: 823.7;Choroid plexus epithelial cells: 579.8;Corticotrophs: 481.1;Lactotrophs: 890.4;Oligodendrocyte progenitor cells: 1362.7;Other brain neurons: 628.4;Pancreatic islet cells: 1236.4;Renal collecting duct intercalated cells: 758.3;Retinal ganglion cells: 1317.2;Somatotrophs: 451.6" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 1361.5;Ductal cells: 758.3;Glial cells: 1362.7;Neuronal cells: 1317.2;Pancreatic islet cells: 1236.4;Pituitary endocrine cells: 890.4" "Cell type enhanced" "Detected in all" "mammillary body: 4377.5" "Cancer enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 16.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.2;Neuroblastoma: 3.3" "Colon - Colon enteroendocrine cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Neurons: 36203.9" "Tissue enriched" "Detected in single" 9745 "cerebral cortex: 974484.5" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" NA NA 44000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: " "unprognostic (2.62e-2)" "unprognostic (1.63e-2)" "unprognostic (7.19e-2)" "unprognostic (8.62e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (3.85e-1)" HSD17B2 "HSD17, SDR9C2" ENSG00000086696 "Hydroxysteroid 17-beta dehydrogenase 2" P37059 16 82035004-82098534 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 403.6;liver: 203.6;placenta: 358.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 432.3;Cholangiocytes: 262.7;Colonocytes: 215.8;Endometrial glandular cells: 242.9;Enterocytes: 491.2;Hepatocytes: 235.1;Lacrimal acinar cells: 164.9;Pancreatic duct cells: 154.1;Urothelial cells: 214.3" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 214.3;Ductal cells: 262.7;Enterocytes: 491.2;Glandular cells: 242.9;Hepatocytes: 235.1;Secretory cells: 432.3" "Cell type enriched" "Detected in single" 4 "fibroblast: 3.3" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 106.8;Pancreatic Adenocarcinoma (TCGA): 71.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 31.8;pancreatic cancer: 35.3" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells, Stomach - Gastric mucous cells" "Group enriched" "Detected in some" 5 "midbrain: 2.2;pons and medulla: 3.4" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Hepatocytes: 36385625.1" "Group enriched" "Detected in some" "intestine: 10995630.8;liver: 17588141.4" "HPA021826, HPA050235" Enhanced Approved "Endoplasmic reticulum" NA NA "Cluster 77: Intestine - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 8 "Endoplasmic reticulum" "HPA021826: , HPA050235: " "unprognostic (2.36e-2)" "unprognostic (1.60e-1)" "unprognostic (8.49e-2)" "unprognostic (4.96e-3)" "unprognostic (1.22e-1)" "unprognostic (1.20e-2)" "unprognostic (2.81e-1)" "unprognostic (5.86e-2)" "unprognostic (2.95e-1)" "unprognostic (2.20e-1)" "unprognostic (2.77e-1)" "unprognostic (2.38e-2)" "unprognostic (7.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.63e-1)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (6.21e-4)" "unprognostic (2.53e-2)" "unprognostic (1.52e-1)" "unprognostic (3.30e-1)" "unprognostic (1.38e-1)" "unprognostic (1.69e-1)" "unprognostic (4.52e-2)" "unprognostic (1.69e-1)" "unprognostic (2.28e-1)" HSD3B1 "HSD3B, HSDB3, SDR11E1" ENSG00000203857 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1" P14060 1 119507198-119515054 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "placenta: 73.1" "Cell type enhanced" "Detected in some" "Enterocytes: 44.6;Extravillous trophoblasts: 266.6;Migrating cytotrophoblasts: 142.3;Syncytiotrophoblasts: 782.0" "Cell type enriched" "Detected in some" 17 "Trophoblast cells: 782.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 15.5;Gastric cancer: 12.8;testis cancer: 24.4" "Skin - Sebaceous gland cells" "Cell type enriched" "Detected in single" 172 "Granulosa cells: 17244.2" "Not detected" "Not detected" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium transition zone" Yes NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 8 "Nucleoli, Endoplasmic reticulum, Primary cilium" "Microtubules, Cytokinetic bridge, Primary cilium transition zone" "HPA043261: , HPA043264: , HPA044028: " "unprognostic (5.46e-3)" "unprognostic (1.41e-2)" HSD3B2 SDR11E2 ENSG00000203859 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2" P26439 1 119414931-119423035 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" "Isomerase, Multifunctional enzyme, Oxidoreductase" "Congenital adrenal hyperplasia, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 53 "adrenal gland: 2103.4" "Cell type enriched" "Detected in some" 23 "Adrenal cortex cells: 2208.4" "Cell type enriched" "Detected in some" 58 "Adrenal endocrine cells: 2208.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 18 "skin cancer: 9.2" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells" "Cell type enriched" "Detected in single" 41 "Granulosa cells: 4132.8" "Not detected" "Not detected" "HPA043261, HPA043264, HPA044028" Supported Approved "Nucleoli,Endoplasmic reticulum,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium transition zone" Yes NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 "Endoplasmic reticulum, Primary cilium" "Nucleoli, Microtubules, Cytokinetic bridge, Primary cilium transition zone" "HPA043261: , HPA043264: , HPA044028: " "unprognostic (7.33e-2)" "unprognostic (2.75e-1)" HSD3B7 "C(27)-3BETA-HSD, SDR11E3" ENSG00000099377 "Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7" Q9H2F3 16 30985207-30989147 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Steroidogenesis" Oxidoreductase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 131.6" "Cell type enhanced" "Detected in many" "Cholangiocytes: 26.9;Decidual stromal cells: 44.5;Early spermatids: 49.0;Enteric stem cells: 26.0;Enteric transient amplifying cells: 28.6;Enterocytes: 38.4;Hepatocytes: 70.7;Pancreatic duct cells: 26.5;Paneth cells: 38.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 70.7;Spermatogenic cell types: 49.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "basophil: 61.4;eosinophil: 27.3" "Lineage enriched" "Detected in many" 38 "granulocytes: 61.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Hepatocytes: 978310.0;Pancreas epithelial cells: 272414.5" "Tissue enhanced" "Detected in some" "liver: 6866111.2" "HPA015965, HPA050521, HPA060847" Approved Enhanced "Lipid droplets" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 48 "Lipid droplets" "HPA015965: , HPA050521: , HPA060847: " "unprognostic (8.68e-2)" "unprognostic (1.03e-3)" "unprognostic (1.80e-1)" "unprognostic (6.03e-2)" "unprognostic (1.12e-2)" "unprognostic (1.18e-1)" "unprognostic (1.76e-2)" "unprognostic (2.92e-1)" "unprognostic (8.17e-3)" "unprognostic (1.22e-1)" "unprognostic (6.76e-2)" "unprognostic (1.17e-2)" "unprognostic (1.08e-1)" "unprognostic (3.45e-2)" "unprognostic (3.06e-2)" "unprognostic (3.85e-3)" "unprognostic (5.17e-2)" "unprognostic (8.39e-2)" "unprognostic (2.55e-1)" "unprognostic (1.43e-1)" "unprognostic (7.75e-2)" "unprognostic (6.15e-3)" "unprognostic (2.19e-1)" "unprognostic (9.10e-2)" "unprognostic (1.23e-1)" "unprognostic (2.80e-1)" "unprognostic (2.43e-1)" "unprognostic (2.94e-2)" "unprognostic (3.20e-2)" "unprognostic (4.69e-2)" "unprognostic (2.76e-1)" HSDL1 SDR12C3 ENSG00000103160 "Hydroxysteroid dehydrogenase like 1" Q3SXM5 16 84122141-84145192 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 59.2;Platelets: 60.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "cerebral cortex: 5161132.5" HPA045745 Supported "Vesicles,Intermediate filaments,Mitochondria" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 79: Photoreceptor cells - Phototransduction" 15 Mitochondria "Vesicles, Intermediate filaments" "HPA045745: " "unprognostic (5.05e-2)" "unprognostic (1.86e-1)" "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (6.79e-2)" "unprognostic (1.61e-2)" "unprognostic (2.82e-1)" "potential prognostic favorable (2.97e-5)" "unprognostic (1.49e-1)" "unprognostic (3.95e-2)" "potential prognostic favorable (1.67e-7)" "unprognostic (1.68e-1)" "unprognostic (7.24e-2)" "unprognostic (6.97e-3)" "unprognostic (7.57e-3)" "unprognostic (1.57e-2)" "unprognostic (3.41e-1)" "unprognostic (5.02e-3)" "unprognostic (6.95e-2)" "unprognostic (2.46e-1)" "unprognostic (1.16e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (2.39e-1)" "unprognostic (3.36e-2)" "unprognostic (7.09e-2)" "unprognostic (3.76e-1)" "unprognostic (7.34e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (4.20e-5)" "unprognostic (7.87e-2)" HSF2 ENSG00000025156 "Heat shock transcription factor 2" Q03933 6 122399551-122433119 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 101.0;Late primary spermatocytes: 120.9;Myonuclei: 102.2;Thymic myoid cells: 133.2;Undifferentiated spermatogonia: 97.6" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 120.9;Stromal cells: 133.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 52 "Granulosa cells: 5217.9" "Not detected" "Not detected" "CAB016067, HPA031455" Approved Supported Nucleoplasm No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 27 Nucleoplasm "CAB016067: , HPA031455: " "unprognostic (1.35e-2)" "unprognostic (6.44e-3)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (3.24e-1)" "unprognostic (1.39e-1)" "unprognostic (1.03e-1)" "unprognostic (5.53e-3)" "unprognostic (6.01e-3)" "unprognostic (1.25e-1)" "unprognostic (8.66e-2)" "potential prognostic favorable (5.97e-4)" "unprognostic (1.98e-1)" "unprognostic (3.15e-2)" "validated prognostic unfavorable (6.25e-7)" "validated prognostic unfavorable (1.74e-4)" "unprognostic (2.75e-2)" "unprognostic (2.94e-1)" "unprognostic (2.11e-1)" "unprognostic (8.93e-2)" "unprognostic (2.43e-1)" "unprognostic (6.37e-2)" "unprognostic (1.07e-3)" "unprognostic (7.62e-2)" "unprognostic (1.72e-1)" "unprognostic (1.51e-1)" "unprognostic (1.32e-3)" "unprognostic (1.33e-1)" "unprognostic (3.32e-2)" "unprognostic (1.54e-1)" "unprognostic (7.91e-3)" "unprognostic (1.51e-1)" HSP90AA1 "FLJ31884, Hsp89, Hsp90, HSP90N, HSPC1, HSPCA" ENSG00000080824 "Heat shock protein 90 alpha family class A member 1" P07900 14 102080742-102139699 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 6812.2;Pancreatic duct cells: 6948.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 4776250619.7" "Low tissue specificity" "Detected in all" "CAB002058, HPA047290" Approved Supported Nucleoplasm,Cytosol NA NA 110000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 75: Non-specific - Chaperones and protein folding" 500 Cytosol Nucleoplasm "CAB002058: , HPA047290: " "unprognostic (2.47e-2)" "unprognostic (1.41e-3)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (1.77e-1)" "unprognostic (2.93e-1)" "unprognostic (3.28e-1)" "potential prognostic unfavorable (6.86e-5)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (1.39e-1)" "potential prognostic favorable (4.80e-6)" "unprognostic (2.05e-2)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (1.15e-5)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "unprognostic (1.44e-3)" "unprognostic (1.92e-1)" "unprognostic (2.22e-1)" "unprognostic (3.92e-2)" "unprognostic (1.48e-3)" "unprognostic (2.46e-2)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (2.81e-2)" "unprognostic (2.56e-1)" "unprognostic (7.65e-2)" "unprognostic (1.22e-1)" "unprognostic (2.61e-1)" "unprognostic (4.62e-1)" "unprognostic (1.29e-1)" "unprognostic (2.42e-2)" HSPA1A "HSP70-1, HSPA1" ENSG00000204389 "Heat shock protein family A (Hsp70) member 1A" P0DMV8 6 31815543-31817946 "Disease related genes, Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 395.9;Bergmann glia: 176.6;Ependymal cells: 349.6;Microglia: 1396.3;Oligodendrocytes: 190.1" "Group enriched" "Detected in many" 12 "Ciliated cells: 349.6;Glial cells: 1396.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1466.5;endothelial cell: 1181.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "granulocytes: 6.9;monocytes: 3.6;T-cells: 3.1" "Cancer enhanced" "Detected in many" "cervical cancer: 45.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB017451, CAB032815, HPA052504" Supported Approved "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" "Intracellular and membrane" Receptor NA Yes 100000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 104: Brain endothelial cells - Blood brain barrier" 326 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "CAB017451: , CAB032815: , HPA052504: " "unprognostic (3.59e-2)" "unprognostic (6.42e-2)" "unprognostic (4.07e-1)" "unprognostic (6.46e-3)" "unprognostic (1.13e-1)" "unprognostic (2.86e-1)" "unprognostic (1.80e-2)" "unprognostic (2.63e-1)" "unprognostic (1.54e-1)" "unprognostic (1.42e-1)" "unprognostic (2.08e-3)" "unprognostic (4.04e-2)" "unprognostic (2.36e-1)" "unprognostic (1.04e-3)" "unprognostic (1.06e-1)" "unprognostic (4.48e-2)" "unprognostic (4.08e-1)" "unprognostic (2.23e-1)" "unprognostic (9.49e-2)" "potential prognostic unfavorable (3.20e-5)" "unprognostic (7.76e-3)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (2.07e-2)" "unprognostic (4.86e-2)" "unprognostic (1.70e-1)" "unprognostic (1.10e-1)" "unprognostic (2.12e-1)" "unprognostic (3.79e-2)" "unprognostic (2.18e-1)" "unprognostic (1.40e-1)" HSPA1B HSP70-2 ENSG00000204388 "Heat shock protein family A (Hsp70) member 1B" P0DMV9 6 31827738-31830254 "Predicted intracellular proteins" "Host-virus interaction, Stress response" "Chaperone, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Astrocytes: 179.1;Ependymal cells: 337.4;Microglia: 551.8" "Group enriched" "Detected in some" 10 "Ciliated cells: 337.4;Glial cells: 551.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 558.7;endothelial cell: 432.4;ependymal cell: 350.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 7.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB008640, HPA052504" Approved Supported "Vesicles,Cytosol,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA Yes "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 104: Brain endothelial cells - Blood brain barrier" 76 "Vesicles, Cytosol, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "CAB008640: , HPA052504: " "unprognostic (1.35e-1)" "unprognostic (3.08e-1)" "unprognostic (2.44e-1)" "unprognostic (1.29e-1)" "unprognostic (7.95e-2)" "unprognostic (1.77e-1)" "unprognostic (2.58e-1)" "unprognostic (2.86e-1)" "unprognostic (1.59e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (8.31e-4)" "unprognostic (1.44e-1)" "unprognostic (1.35e-2)" "unprognostic (3.63e-2)" "unprognostic (3.43e-1)" "unprognostic (5.85e-1)" "unprognostic (2.79e-1)" "unprognostic (4.04e-3)" "unprognostic (1.52e-1)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (6.51e-3)" "unprognostic (3.04e-2)" "unprognostic (9.72e-2)" "unprognostic (1.55e-1)" "unprognostic (1.35e-1)" "unprognostic (5.19e-3)" "unprognostic (1.84e-1)" "unprognostic (2.23e-1)" "unprognostic (3.12e-1)" HSPA1L "HSP70-HOM, hum70t" ENSG00000204390 "Heat shock protein family A (Hsp70) member 1 like" P34931 6 31809619-31815283 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "testis: 54.8" "Cell type enhanced" "Detected in some" "Astrocytes: 1.5;Ependymal cells: 2.7;Late spermatids: 1.4;Microglia: 1.7;Oligodendrocytes: 1.2;Podocytes: 1.5" "Cell type enhanced" "Detected in some" "Ciliated cells: 2.7;Glial cells: 1.7;Renal nephron cells: 1.5;Spermatogenic cell types: 1.4" "Cell type enhanced" "Detected in many" "ependymal cell: 4.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "blood vessel: 14723379.4" "HPA043285, HPA052504" Enhanced Approved "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 102: Non-specific - Mixed function" 51 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "HPA043285: , HPA052504: " "unprognostic (1.26e-1)" "unprognostic (4.24e-2)" "unprognostic (8.61e-3)" "unprognostic (1.67e-1)" "unprognostic (5.31e-2)" HSPA2 ENSG00000126803 "Heat shock protein family A (Hsp70) member 2" P54652 14 64535905-64546173 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Stress response" Chaperone "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 344.7;skeletal muscle: 177.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 453.3;Extravillous trophoblasts: 732.7;Hepatic stellate cells: 193.6;Late primary spermatocytes: 716.2;Migrating cytotrophoblasts: 163.3;Oligodendrocytes: 152.1" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 716.2;Trophoblast cells: 732.7" "Cell type enhanced" "Detected in many" "ependymal cell: 67.8;oligodendrocyte: 184.0;pericyte: 75.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 150973718.4;Skeletal myofibers: 193755616.8" "Low tissue specificity" "Detected in all" "HPA000798, HPA052504" Enhanced Supported Approved "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA NA 89000000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 133 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "HPA000798: , HPA052504: " "unprognostic (1.34e-1)" "unprognostic (5.10e-3)" "unprognostic (1.76e-3)" "unprognostic (3.16e-1)" "unprognostic (1.05e-1)" "unprognostic (1.17e-1)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.62e-2)" "unprognostic (4.34e-1)" "unprognostic (1.06e-1)" "unprognostic (1.55e-1)" "unprognostic (1.99e-1)" "unprognostic (4.97e-2)" "unprognostic (1.13e-1)" "unprognostic (3.40e-3)" "unprognostic (6.77e-2)" "unprognostic (3.14e-2)" "unprognostic (5.10e-2)" "unprognostic (5.82e-2)" "unprognostic (9.54e-3)" "unprognostic (3.47e-1)" "unprognostic (1.74e-1)" "unprognostic (3.08e-1)" "unprognostic (8.88e-2)" "unprognostic (7.24e-2)" "unprognostic (1.59e-1)" "unprognostic (6.20e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-1)" "unprognostic (9.43e-2)" HSPA4 "HS24/P52, HSPH2" ENSG00000170606 "Heat shock protein family A (Hsp70) member 4" P34932 5 133052013-133106449 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 303.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 196813945.6" "Tissue enhanced" "Detected in all" "cerebral cortex: 404121032.8" "HPA010023, CAB025529" Uncertain Approved Nucleoplasm,Cytosol NA NA 13000000 "Cluster 29: Non-specific - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 75: Non-specific - Chaperones and protein folding" 209 "Nucleoplasm, Cytosol" "CAB025529: , HPA010023: " "unprognostic (4.36e-2)" "unprognostic (6.69e-2)" "unprognostic (1.90e-1)" "unprognostic (2.17e-3)" "unprognostic (1.16e-2)" "unprognostic (1.61e-2)" "unprognostic (1.40e-1)" "unprognostic (7.83e-3)" "unprognostic (1.57e-2)" "unprognostic (1.65e-3)" "potential prognostic favorable (2.28e-5)" "unprognostic (2.31e-1)" "unprognostic (9.91e-2)" "unprognostic (3.24e-3)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (5.95e-2)" "unprognostic (9.26e-2)" "unprognostic (1.39e-1)" "unprognostic (5.60e-2)" "unprognostic (3.84e-2)" "unprognostic (2.12e-3)" "unprognostic (3.67e-3)" "unprognostic (2.54e-2)" "unprognostic (7.18e-2)" "unprognostic (7.45e-2)" "unprognostic (5.16e-2)" "unprognostic (1.56e-1)" "unprognostic (1.44e-1)" "unprognostic (9.75e-3)" "unprognostic (4.14e-1)" HSPA4L "APG-1, HSPH3, Osp94" ENSG00000164070 "Heat shock protein family A (Hsp70) member 4 like" O95757 4 127781821-127840733 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 101.7" "Cell type enhanced" "Detected in many" "Early spermatids: 539.2;Late primary spermatocytes: 409.6;Late spermatids: 1609.1;Pancreatic duct cells: 240.3" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 1609.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.1" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "cerebral cortex: 62375504.3" "CAB034450, HPA039149, HPA061446" Enhanced Approved "Centrosome,Cytosol,Perinuclear theca,Calyx" NA NA 640000 "Cluster 22: Eosinophils - Transcription" "Cluster 47: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 41 Cytosol "Centrosome, Perinuclear theca, Calyx" "CAB034450: , HPA039149: , HPA061446: " "unprognostic (3.21e-1)" "unprognostic (2.85e-1)" "unprognostic (7.22e-2)" "unprognostic (5.13e-2)" "unprognostic (1.03e-2)" "unprognostic (3.79e-1)" "unprognostic (3.54e-1)" "unprognostic (5.98e-3)" "unprognostic (5.91e-2)" "potential prognostic unfavorable (1.08e-4)" "validated prognostic favorable (1.32e-10)" "validated prognostic favorable (8.64e-4)" "unprognostic (7.97e-2)" "unprognostic (1.84e-2)" "unprognostic (3.44e-1)" "unprognostic (1.00e-1)" "unprognostic (4.63e-3)" "unprognostic (7.85e-2)" "unprognostic (8.46e-2)" "unprognostic (1.06e-2)" "unprognostic (2.34e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (9.04e-2)" "unprognostic (2.42e-1)" "unprognostic (5.01e-1)" "unprognostic (1.33e-1)" "unprognostic (1.85e-1)" "unprognostic (1.55e-1)" "unprognostic (4.71e-2)" HSPA5 "BiP, GRP78" ENSG00000044574 "Heat shock protein family A (Hsp70) member 5" P11021 9 125234853-125241382 "Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Chaperone, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal basal cells: 2675.2;Epididymal principal cells: 2135.9;Extravillous trophoblasts: 1248.3;Plasma cells: 1402.5;Syncytiotrophoblasts: 1846.5" "Cell type enhanced" "Detected in all" "Basal cells: 2675.2;Reproductive supporting cells: 2135.9;Trophoblast cells: 1846.5" "Cell type enhanced" "Detected in all" "endothelial cell: 281.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Pancreas epithelial cells: 4161589296.1;Pancreatic islets: 5287049905.1" "Tissue enriched" "Detected in all" "pancreas: 8682461670.6" "CAB005221, HPA038845, HPA038846" Enhanced Uncertain "Cytosol,Mid piece,Principal piece,End piece,Annulus" "Intracellular and membrane" Enzyme NA NA 540000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 449 "Cytosol, Annulus" "Mid piece, Principal piece, End piece" "CAB005221: , HPA038845: , HPA038846: " "potential prognostic unfavorable (3.50e-4)" "unprognostic (9.55e-2)" "unprognostic (2.39e-1)" "unprognostic (2.26e-2)" "unprognostic (1.02e-1)" "unprognostic (3.81e-3)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (7.65e-3)" "unprognostic (5.89e-2)" "unprognostic (1.44e-3)" "unprognostic (2.56e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (4.57e-3)" "unprognostic (3.52e-3)" "unprognostic (6.09e-2)" "unprognostic (5.84e-3)" "unprognostic (3.32e-2)" "unprognostic (3.57e-2)" "unprognostic (2.09e-1)" "unprognostic (2.53e-2)" "unprognostic (5.46e-2)" "unprognostic (1.68e-2)" "unprognostic (1.72e-1)" "unprognostic (6.16e-2)" "unprognostic (4.41e-2)" "unprognostic (6.59e-2)" "unprognostic (7.42e-2)" "unprognostic (8.46e-2)" "unprognostic (5.90e-2)" "unprognostic (2.50e-2)" HSPA6 HSP70B' ENSG00000173110 "Heat shock protein family A (Hsp70) member 6" P17066 1 161524540-161526894 "Plasma proteins, Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 88.5" "Cell type enriched" "Detected in some" 5 "Microglia: 14.7" "Cell type enriched" "Detected in some" 5 "Glial cells: 14.7" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 20.5;endothelial cell: 8.6;leukocyte: 23.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 125.6" "Immune cell enriched" "Detected in many" 7 "neutrophil: 319.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 319.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Fallopian tube cells: 11642310.8;Granulosa cells: 10430259.2;Keratinocytes: 41705207.1;Large ducts: 29292744.1;Smooth muscle cells: 39090236.6" "Tissue enhanced" "Detected in many" "intestine: 37265756.4;Stomach: 59107776.2" "CAB017452, HPA028549, HPA052504" Approved Approved "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA NA 49000000 "Cluster 28: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 11: Neuronal - Sensory perception" "Cluster 102: Non-specific - Mixed function" 53 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "CAB017452: , HPA028549: , HPA052504: " "unprognostic (1.28e-1)" "unprognostic (2.77e-2)" "unprognostic (2.65e-2)" "unprognostic (5.32e-2)" "unprognostic (2.21e-2)" "unprognostic (2.89e-1)" "unprognostic (1.49e-2)" "unprognostic (7.16e-2)" "unprognostic (6.34e-3)" "unprognostic (1.88e-1)" "unprognostic (1.51e-3)" "unprognostic (3.00e-2)" "unprognostic (3.06e-1)" "unprognostic (1.98e-3)" "unprognostic (2.92e-1)" "unprognostic (7.79e-2)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (8.23e-2)" "unprognostic (3.39e-1)" "unprognostic (1.14e-2)" "unprognostic (5.86e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.66e-6)" "unprognostic (7.83e-2)" "unprognostic (2.56e-1)" "unprognostic (1.37e-3)" "unprognostic (2.24e-1)" "unprognostic (6.75e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (5.18e-2)" HSPA8 "HSC70, HSC71, HSP73, HSPA10" ENSG00000109971 "Heat shock protein family A (Hsp70) member 8" P11142 11 123057489-123063230 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, Host-virus interaction, mRNA processing, mRNA splicing, Stress response, Transcription, Transcription regulation" "Chaperone, Hydrolase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 1372.1;Epididymal principal cells: 1371.6;Syncytiotrophoblasts: 1639.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB002056, HPA052504" Uncertain Supported "Vesicles,Perinuclear theca,Calyx,Flagellar centriole,Annulus" NA Yes 210000000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 697 "Vesicles, Flagellar centriole, Annulus" "Perinuclear theca, Calyx" "CAB002056: , HPA052504: " "unprognostic (4.00e-3)" "unprognostic (8.77e-3)" "unprognostic (7.60e-2)" "unprognostic (3.63e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" "unprognostic (4.27e-2)" "unprognostic (4.83e-3)" "potential prognostic favorable (6.02e-7)" "unprognostic (3.11e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (5.07e-5)" "unprognostic (1.08e-1)" "unprognostic (2.54e-2)" "unprognostic (8.25e-3)" "unprognostic (9.36e-2)" "unprognostic (4.62e-2)" "unprognostic (6.21e-3)" "unprognostic (2.64e-2)" "unprognostic (2.72e-1)" "unprognostic (8.81e-2)" "unprognostic (2.52e-1)" "unprognostic (2.24e-2)" "unprognostic (3.57e-1)" "unprognostic (3.73e-1)" "unprognostic (1.22e-1)" "unprognostic (6.57e-2)" "unprognostic (2.35e-1)" "unprognostic (8.42e-2)" HSPA9 "GRP75, HSPA9B, mot-2, mthsp75, PBP74" ENSG00000113013 "Heat shock protein family A (Hsp70) member 9" P38646 5 138553756-138575675 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 620.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA000898, CAB005219" Supported Supported Mitochondria NA NA 4100000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 118 Mitochondria "CAB005219: , HPA000898: " "unprognostic (2.11e-1)" "unprognostic (7.61e-3)" "unprognostic (1.67e-1)" "unprognostic (1.54e-2)" "potential prognostic favorable (8.25e-4)" "unprognostic (2.04e-1)" "unprognostic (2.91e-1)" "unprognostic (2.09e-3)" "unprognostic (8.99e-2)" "potential prognostic unfavorable (7.23e-6)" "potential prognostic favorable (5.36e-9)" "unprognostic (2.40e-2)" "unprognostic (5.61e-2)" "unprognostic (3.93e-1)" "unprognostic (1.36e-1)" "unprognostic (9.22e-3)" "unprognostic (1.44e-1)" "unprognostic (1.42e-1)" "unprognostic (1.58e-1)" "unprognostic (1.62e-1)" "unprognostic (3.04e-2)" "unprognostic (7.03e-3)" "unprognostic (9.13e-2)" "unprognostic (1.13e-1)" "unprognostic (4.13e-2)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (2.29e-1)" "unprognostic (1.42e-1)" "unprognostic (2.02e-2)" "unprognostic (7.92e-2)" HSPB11 "C1orf41, FAP232, HSPCO34, IFT25, PP25" ENSG00000081870 "Heat shock protein family B (small) member 11" Q9Y547 1 53916574-53945699 "Predicted intracellular proteins" "Differentiation, Protein transport, Spermatogenesis, Stress response, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 284.2;Fallopian tube ciliated cells: 319.0;Respiratory ciliated cells: 367.6" "Cell type enhanced" "Detected in all" "Ciliated cells: 367.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 24212698.3" "Tissue enhanced" "Detected in all" "fallopian tube: 20890775.7" HPA030140 Uncertain Approved "Mid piece,Principal piece,End piece" NA NA 110000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 62 "Mid piece, Principal piece, End piece" "HPA030140: " "unprognostic (1.06e-1)" "unprognostic (9.26e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (5.76e-4)" "unprognostic (6.19e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (2.79e-4)" "unprognostic (1.19e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (1.05e-5)" "unprognostic (6.30e-2)" "unprognostic (4.50e-2)" "unprognostic (6.70e-2)" "potential prognostic unfavorable (1.15e-7)" "unprognostic (2.42e-2)" "unprognostic (1.36e-2)" "unprognostic (7.65e-3)" "unprognostic (1.06e-1)" "unprognostic (4.36e-1)" "unprognostic (9.11e-3)" "unprognostic (5.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (5.74e-3)" "unprognostic (8.42e-2)" "unprognostic (2.16e-1)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (1.69e-2)" HSPB6 "FLJ32389, Hsp20, PPP1R91" ENSG00000004776 "Heat shock protein family B (small) member 6" O14558 19 35754566-35758079 "Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 2832.4;tongue: 1642.4" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 734.3;Endometrial stromal cells: 111.6;Fibroblasts: 153.0;Hepatic stellate cells: 264.6;Late spermatids: 87.1;Leydig cells: 254.2;Ovarian stromal cells: 106.8;Pericytes: 129.7;Peritubular myoid cells: 195.1;Smooth muscle cells: 264.8;Thymic myoid cells: 311.4;Vascular smooth muscle cells: 240.7" "Cell type enhanced" "Detected in many" "Leydig cells: 254.2;Mural cells: 240.7;Smooth muscle cells: 264.8;Stellate cells: 264.6;Stromal cells: 734.3" "Cell type enhanced" "Detected in some" "ependymal cell: 6.6;vascular associated smooth muscle cell: 22.9" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 248.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 63.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Lung - Smooth muscle cells, Pituitary gland - Fibroblasts, Skeletal muscle - Skeletal myocytes, Spleen - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 4989658457.6" "Tissue enriched" "Detected in all" "skeletal muscle: 8246285840.0" "CAB001974, HPA044153, HPA054811" Enhanced Supported "Nuclear speckles,Mitochondria,Cytosol" "Intracellular and membrane" Other NA NA 380000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 4 "Mitochondria, Cytosol" "Nuclear speckles" "CAB001974: , HPA044153: , HPA054811: " "unprognostic (3.29e-3)" "unprognostic (1.29e-1)" "unprognostic (1.92e-2)" "unprognostic (1.21e-1)" "unprognostic (3.06e-3)" "unprognostic (3.69e-2)" "unprognostic (3.83e-3)" "unprognostic (7.13e-3)" "unprognostic (2.81e-2)" "unprognostic (3.20e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-2)" "unprognostic (1.10e-3)" "unprognostic (6.86e-2)" "unprognostic (2.81e-3)" "unprognostic (5.23e-3)" "unprognostic (6.69e-2)" "unprognostic (6.08e-2)" "unprognostic (2.14e-1)" "unprognostic (1.76e-1)" "unprognostic (1.99e-1)" "unprognostic (1.18e-1)" "unprognostic (2.11e-1)" "unprognostic (1.35e-2)" "unprognostic (4.61e-2)" "unprognostic (2.53e-2)" "unprognostic (2.68e-1)" "unprognostic (1.05e-2)" "unprognostic (1.52e-1)" "unprognostic (6.68e-2)" "unprognostic (1.71e-2)" HSPBP1 FES1 ENSG00000133265 "HSPA (Hsp70) binding protein 1" Q9NZL4 19 55262223-55280381 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 118.3" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 136.8;Esophageal basal cells: 90.7;Fallopian tube ciliated cells: 109.5;Respiratory ciliated cells: 144.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 144.7" "Cell type enhanced" "Detected in all" "ependymal cell: 69.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB005865, HPA070398, HPA071444" Supported Approved Vesicles,Centrosome,Cytosol NA NA 11000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 62 Cytosol "Vesicles, Centrosome" "CAB005865: , HPA070398: , HPA071444: " "unprognostic (2.27e-2)" "unprognostic (1.89e-1)" "unprognostic (1.65e-1)" "unprognostic (2.96e-2)" "unprognostic (2.40e-1)" "unprognostic (1.85e-1)" "unprognostic (1.19e-1)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (4.93e-1)" "unprognostic (2.97e-3)" "validated prognostic unfavorable (3.53e-4)" "validated prognostic unfavorable (1.10e-4)" "unprognostic (1.77e-3)" "unprognostic (2.36e-2)" "unprognostic (1.49e-1)" "unprognostic (1.40e-1)" "unprognostic (8.08e-2)" "unprognostic (5.81e-2)" "unprognostic (3.90e-3)" "unprognostic (1.14e-1)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (1.79e-1)" "unprognostic (9.44e-2)" "unprognostic (1.41e-1)" "unprognostic (1.11e-1)" "unprognostic (9.05e-2)" "unprognostic (1.87e-1)" HSPH1 "HSP105A, HSP105B, KIAA0201, NY-CO-25" ENSG00000120694 "Heat shock protein family H (Hsp110) member 1" Q92598 13 31134973-31162388 "Cancer-related genes, Predicted intracellular proteins" "Stress response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 694.2;monocytes: 942.6;Pancreatic duct cells: 2047.4" "Cell type enhanced" "Detected in all" "Ductal cells: 2047.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 112409302.9;Microglia and Neuropil: 111444386.8;Neurons: 86329721.9" "Tissue enriched" "Detected in all" "cerebral cortex: 244940006.0" "CAB002060, HPA028675, HPA031569" Uncertain Enhanced Nucleoplasm,Cytosol No Yes 1000000 "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 75: Non-specific - Chaperones and protein folding" 78 Cytosol Nucleoplasm "CAB002060: , HPA028675: , HPA031569: " "unprognostic (4.50e-2)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (1.25e-1)" "unprognostic (8.26e-2)" "unprognostic (1.54e-1)" "unprognostic (3.33e-1)" "unprognostic (5.81e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (5.47e-2)" "unprognostic (2.00e-1)" "unprognostic (6.16e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (1.81e-2)" "unprognostic (1.20e-2)" "unprognostic (1.06e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.15e-1)" "unprognostic (5.65e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (1.13e-6)" "unprognostic (2.68e-1)" "unprognostic (2.59e-1)" "unprognostic (6.21e-2)" "unprognostic (2.14e-1)" "unprognostic (3.80e-1)" "unprognostic (4.56e-1)" "unprognostic (2.32e-1)" "unprognostic (3.44e-2)" HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "parathyroid gland: 12.3;testis: 8.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 23.4;Brain inhibitory neurons: 19.7;cDC: 42.1;Hepatic stellate cells: 45.2;Hofbauer cells: 15.0;Late primary spermatocytes: 21.6;Macrophages: 30.1;monocytes: 16.0;Other brain neurons: 25.0;Undifferentiated spermatogonia: 25.7" "Group enriched" "Detected in many" 4 "dendritic cells: 42.1;Mononuclear phagocytes: 30.1;Neuronal cells: 25.0;Spermatogenic cell types: 25.7;Stellate cells: 45.2" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 134.7;mammillary body: 335.5" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 3.1;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.5;Head and Neck Squamous Cell Carcinoma (TCGA): 5.0;Lung Squamous Cell Carcinoma (TCGA): 2.5;Testicular Germ Cell Tumor (TCGA): 1.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065367, HPA073617, CAB080587" Approved Supported Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium" NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 1 "Nucleoplasm, Plasma membrane" "Vesicles, Primary cilium" "CAB080587: , HPA065367: , HPA073617: " "unprognostic (1.43e-1)" "unprognostic (3.78e-2)" "unprognostic (1.54e-3)" "unprognostic (8.63e-2)" "unprognostic (1.48e-2)" "unprognostic (9.57e-2)" "unprognostic (1.76e-1)" "unprognostic (1.58e-2)" "unprognostic (3.13e-2)" "unprognostic (1.50e-1)" HYDIN "CILD5, DKFZp434D0513, KIAA1864, PPP1R31" ENSG00000157423 "HYDIN axonemal central pair apparatus protein" Q4G0P3 16 70802084-71230722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 5.0;retina: 6.3" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 620.2;Endometrial ciliated cells: 524.9;Ependymal cells: 1646.9;Epididymal efferent duct ciliated cells: 529.2;Fallopian tube ciliated cells: 563.0;Respiratory ciliated cells: 1047.6" "Cell type enriched" "Detected in many" 9 "Ciliated cells: 1646.9" "Group enriched" "Detected in all" 5 "choroid plexus epithelial cell: 500.8;ependymal cell: 1758.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24733020.2;Neutrophils: 17889298.8" "Group enriched" "Detected in many" "blood vessel: 2349966.3;bone marrow: 4344167.9;intestine: 6919540.7;lung: 3514139.6" "HPA046282, HPA067155" Enhanced Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle,Primary cilium,Cytosol,Equatorial segment" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Cytokinetic bridge, Primary cilium, Cytosol, Equatorial segment" "Nucleoplasm, Mitotic spindle" "HPA046282: , HPA067155: " "unprognostic (8.05e-2)" "unprognostic (3.63e-2)" "unprognostic (5.58e-2)" "unprognostic (4.23e-3)" "unprognostic (8.68e-2)" "unprognostic (1.29e-1)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (2.10e-4)" "unprognostic (6.03e-2)" "unprognostic (6.93e-2)" HYI HT036 ENSG00000178922 "Hydroxypyruvate isomerase (putative)" Q5T013 1 43450989-43453989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 204.7;Epididymal efferent duct absorptive cells: 131.6;Extravillous trophoblasts: 173.8" "Cell type enhanced" "Detected in all" "Enterocytes: 204.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 30.0" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Adrenocortical cancer: 190.2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islets: 21974975.4" "Low tissue specificity" "Detected in all" HPA040092 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 1: Enterocytes - Absorption and Digestion" 5 "Plasma membrane, Cytosol" "Golgi apparatus" "HPA040092: " "unprognostic (5.32e-2)" "unprognostic (1.01e-3)" "unprognostic (7.38e-2)" "unprognostic (1.45e-1)" "unprognostic (5.15e-2)" "unprognostic (7.29e-2)" "unprognostic (2.77e-2)" "unprognostic (9.36e-3)" "unprognostic (2.68e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (9.65e-5)" "unprognostic (2.20e-1)" "unprognostic (5.78e-2)" "unprognostic (5.13e-3)" "unprognostic (3.50e-2)" "unprognostic (3.15e-2)" "unprognostic (2.63e-1)" "unprognostic (6.34e-3)" "unprognostic (3.65e-3)" "unprognostic (3.40e-2)" "unprognostic (7.29e-3)" "unprognostic (1.95e-1)" "unprognostic (3.59e-2)" "unprognostic (1.49e-1)" "unprognostic (4.68e-3)" "unprognostic (2.99e-1)" "unprognostic (8.93e-2)" "unprognostic (2.07e-1)" "unprognostic (2.22e-1)" "unprognostic (3.12e-2)" "unprognostic (2.60e-1)" IARS1 "IARS, ILRS" ENSG00000196305 "Isoleucyl-tRNA synthetase 1" P41252 9 92210207-92293854 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA029806 Approved Approved Nucleoplasm,Cytosol NA NA 150000 "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 69 "Nucleoplasm, Cytosol" "HPA029806: " "unprognostic (2.27e-3)" "unprognostic (1.26e-2)" "unprognostic (1.39e-3)" "unprognostic (1.26e-1)" "unprognostic (3.24e-2)" "unprognostic (3.06e-1)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (8.96e-3)" "potential prognostic favorable (3.75e-7)" "unprognostic (3.86e-2)" "unprognostic (2.25e-1)" "unprognostic (2.32e-3)" "unprognostic (1.42e-2)" "unprognostic (2.10e-2)" "unprognostic (7.07e-2)" "unprognostic (2.43e-1)" "unprognostic (2.19e-2)" "unprognostic (1.78e-1)" "unprognostic (3.17e-3)" "unprognostic (1.16e-1)" "unprognostic (9.05e-2)" "potential prognostic favorable (3.86e-4)" "unprognostic (6.45e-3)" "unprognostic (2.31e-1)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (6.36e-2)" "unprognostic (1.17e-1)" IARS2 FLJ10326 ENSG00000067704 "Isoleucyl-tRNA synthetase 2, mitochondrial" Q9NSE4 1 220094132-220148041 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Cataract, Deafness, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA024212, HPA024594, HPA024596" Enhanced Enhanced Mitochondria NA NA 88000 "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 32 Mitochondria "HPA024212: , HPA024594: , HPA024596: " "unprognostic (4.28e-2)" "unprognostic (1.29e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (7.99e-4)" "potential prognostic favorable (6.59e-4)" "unprognostic (8.25e-3)" "unprognostic (1.73e-1)" "unprognostic (3.29e-2)" "unprognostic (2.18e-1)" "unprognostic (1.50e-3)" "potential prognostic favorable (2.85e-6)" "unprognostic (1.52e-1)" "unprognostic (3.31e-2)" "unprognostic (9.39e-2)" "unprognostic (9.18e-2)" "unprognostic (1.03e-2)" "unprognostic (1.87e-2)" "unprognostic (7.51e-2)" "unprognostic (3.44e-1)" "unprognostic (5.89e-2)" "unprognostic (6.08e-3)" "potential prognostic unfavorable (5.18e-4)" "unprognostic (2.45e-1)" "unprognostic (3.87e-1)" "unprognostic (7.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.62e-1)" "unprognostic (3.51e-1)" "unprognostic (2.92e-1)" "unprognostic (2.11e-2)" "unprognostic (2.29e-1)" ICA1 "ICA69, ICAp69" ENSG00000003147 "Islet cell autoantigen 1" Q05084 7 8113184-8262687 "Predicted intracellular proteins, Predicted membrane proteins" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 521.2;Cardiomyocytes: 352.3;Distal convoluted tubule cells: 582.3;Early spermatids: 863.2;Late spermatids: 1438.0" "Cell type enhanced" "Detected in many" "Renal nephron cells: 582.3;Spermatogenic cell types: 1438.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "T-reg: 30.0" "Lineage enriched" "Detected in many" 9 "T-cells: 30.0" "Cancer enhanced" "Detected in many" "Neuroblastoma: 88.4" "Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 7119968.9" "Tissue enhanced" "Detected in many" "cerebral cortex: 3753849.7" "HPA017646, HPA061452" Approved Supported Vesicles,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 8: Pancreas - Proteolysis" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 "Vesicles, Cytosol" "HPA017646: , HPA061452: " "unprognostic (1.10e-2)" "unprognostic (6.00e-2)" "unprognostic (3.16e-1)" "unprognostic (5.88e-2)" "unprognostic (2.73e-2)" "unprognostic (1.62e-1)" "unprognostic (4.82e-2)" "unprognostic (3.60e-2)" "unprognostic (1.06e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (2.71e-10)" "unprognostic (2.57e-2)" "unprognostic (1.18e-3)" "unprognostic (3.11e-2)" "unprognostic (1.82e-2)" "unprognostic (3.75e-1)" "unprognostic (3.59e-2)" "unprognostic (3.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (1.91e-1)" "unprognostic (9.63e-2)" "unprognostic (1.49e-1)" "unprognostic (8.17e-2)" "unprognostic (8.34e-3)" "unprognostic (7.33e-2)" "unprognostic (1.25e-1)" "unprognostic (3.04e-1)" "unprognostic (8.93e-2)" "unprognostic (7.24e-3)" "unprognostic (2.81e-2)" ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 233.5;urinary bladder: 200.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 906.0;Alveolar cells type 2: 735.5;Kupffer cells: 314.6;Macrophages: 300.0;monocytes: 568.2;Neutrophils: 1484.9;Transitional alveolar cells: 695.7;Vascular endothelial cells: 507.8" "Cell type enhanced" "Detected in many" "Alveolar cells: 906.0;Endothelial cells: 507.8;Mononuclear phagocytes: 568.2;Neutrophils: 1484.9" "Cell type enriched" "Detected in some" 8 "endothelial cell: 105.4" "Cancer enhanced" "Detected in all" "Lung Adenocarcinoma (TCGA): 244.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 38277670.2;Glomeruli: 40834548.9;Macrophages: 31894531.0" "Group enriched" "Detected in all" "lung: 137496284.8;lymphoid tissue: 49531377.0" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 240000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 36 "Plasma membrane" "Vesicles, Cytosol" "CAB002142: , HPA002126: , HPA004877: " "unprognostic (8.42e-2)" "unprognostic (4.57e-3)" "unprognostic (7.39e-2)" "unprognostic (2.30e-2)" "unprognostic (3.86e-1)" "unprognostic (1.59e-1)" "unprognostic (1.61e-3)" "unprognostic (4.21e-2)" "unprognostic (1.04e-1)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (2.22e-2)" "unprognostic (2.58e-2)" "unprognostic (1.95e-3)" "unprognostic (3.28e-1)" "unprognostic (6.22e-2)" "unprognostic (1.21e-2)" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (4.08e-2)" "unprognostic (2.93e-1)" "unprognostic (2.24e-2)" "unprognostic (1.04e-2)" "unprognostic (8.65e-2)" "unprognostic (1.65e-1)" "potential prognostic favorable (2.21e-4)" "unprognostic (9.78e-2)" "unprognostic (1.21e-1)" "unprognostic (8.87e-3)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" ID1 "bHLHb24, dJ857M17.1.2" ENSG00000125968 "Inhibitor of DNA binding 1" P41134 20 31605283-31606515 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 1049.4;Esophageal apical cells: 3645.3;Esophageal basal cells: 1134.7;Esophageal suprabasal cells: 2030.4;Prostatic club cells: 1685.4;Prostatic hillock cells: 1926.8;Urothelial cells: 866.2;Vascular endothelial cells: 873.5" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 3645.3;Barrier epithelial cells: 1926.8;Glandular cells: 1685.4;Suprabasal cells: 2030.4" "Cell type enriched" "Detected in many" 5 "endothelial cell: 608.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025915, HPA027874, HPA058518, HPA068861" Approved Enhanced Nucleoplasm NA No "Cluster 21: Neutrophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 33 Nucleoplasm "CAB025915: , HPA027874: , HPA058518: , HPA068861: " "unprognostic (4.94e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (4.74e-4)" "unprognostic (1.56e-2)" "unprognostic (9.97e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-2)" "potential prognostic favorable (2.32e-4)" "unprognostic (1.10e-1)" "unprognostic (3.08e-2)" "unprognostic (8.42e-3)" "unprognostic (5.26e-3)" "unprognostic (3.33e-1)" "unprognostic (3.33e-1)" "unprognostic (4.85e-2)" "unprognostic (9.89e-3)" "unprognostic (3.71e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (1.52e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-1)" "unprognostic (1.93e-2)" "unprognostic (1.24e-2)" "unprognostic (1.97e-1)" "unprognostic (2.23e-2)" "unprognostic (1.67e-1)" "unprognostic (1.00e-1)" "unprognostic (2.35e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-3)" "unprognostic (1.95e-2)" IDH1 ENSG00000138413 "Isocitrate dehydrogenase (NADP(+)) 1" O75874 2 208236229-208266074 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glyoxylate bypass, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 501.4" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 343.6;Cytotrophoblasts: 401.9;Hepatocytes: 374.0;Hofbauer cells: 251.4;Urothelial cells: 284.5" "Cell type enhanced" "Detected in all" "Trophoblast cells: 401.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Macrophages, Pancreas - Macrophages, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 695964580.6" "Group enriched" "Detected in all" "liver: 768637345.6;skin: 192524949.0" "CAB033218, HPA035248, HPA057936, CAB062556" Enhanced Approved "Nuclear bodies,Cytosol" NA NA 21000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 7: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 "Nuclear bodies, Cytosol" "CAB033218: , CAB062556: , HPA035248: , HPA057936: " "potential prognostic favorable (3.03e-4)" "unprognostic (4.85e-2)" "unprognostic (3.55e-2)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (3.15e-3)" "unprognostic (2.31e-2)" "unprognostic (7.38e-2)" "unprognostic (8.56e-3)" "potential prognostic unfavorable (5.77e-6)" "unprognostic (7.13e-3)" "unprognostic (7.78e-3)" "unprognostic (5.31e-2)" "unprognostic (1.54e-3)" "unprognostic (4.10e-2)" "unprognostic (5.47e-2)" "unprognostic (4.10e-1)" "unprognostic (2.20e-1)" "unprognostic (5.93e-2)" "unprognostic (2.81e-2)" "unprognostic (3.10e-1)" "unprognostic (1.42e-2)" "unprognostic (8.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.01e-1)" "unprognostic (2.09e-2)" "unprognostic (4.89e-3)" "unprognostic (1.90e-1)" "unprognostic (2.89e-1)" "unprognostic (3.50e-2)" "unprognostic (6.75e-3)" IDH3A ENSG00000166411 "Isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha" P50213 15 78131498-78171945 "Citric acid cycle related proteins, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, FDA approved drug targets, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 92.7" "Cell type enhanced" "Detected in many" "pDCs: 205.6" "Cell type enhanced" "Detected in all" "dendritic cells: 205.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 144.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 481741476.2" "Group enriched" "Detected in all" "cerebral cortex: 210602822.5;heart muscle: 298877477.6" "HPA041465, HPA062971" Supported Enhanced Mitochondria No No 16000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 52: Non-specific - Cellular respiration" "Cluster 23: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 10 Mitochondria "HPA041465: , HPA062971: " "unprognostic (8.71e-2)" "unprognostic (4.76e-2)" "unprognostic (1.30e-1)" "unprognostic (2.41e-2)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (2.71e-2)" "unprognostic (1.04e-1)" "unprognostic (3.52e-1)" "potential prognostic unfavorable (6.15e-4)" "validated prognostic favorable (9.24e-5)" "validated prognostic favorable (4.52e-4)" "unprognostic (1.03e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-3)" "unprognostic (1.59e-1)" "unprognostic (1.19e-1)" "unprognostic (6.56e-2)" "unprognostic (8.43e-2)" "unprognostic (3.59e-1)" "unprognostic (3.83e-1)" "unprognostic (1.51e-2)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.46e-3)" "unprognostic (1.22e-1)" "unprognostic (4.29e-2)" "unprognostic (9.01e-2)" "unprognostic (2.97e-1)" "unprognostic (5.64e-2)" "unprognostic (1.14e-1)" IDH3B RP46 ENSG00000101365 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta" O43837 20 2658395-2664219 "Citric acid cycle related proteins, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 168.4;Late spermatids: 169.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 201663202.9" "Group enriched" "Detected in many" "cerebral cortex: 104710445.9;heart muscle: 147024052.8" "HPA049387, HPA054180" Supported Enhanced Mitochondria NA NA 4200 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 5 Mitochondria "HPA049387: , HPA054180: " "unprognostic (2.25e-1)" "unprognostic (1.85e-2)" "unprognostic (2.84e-1)" "unprognostic (8.35e-2)" "unprognostic (3.01e-1)" "unprognostic (2.16e-1)" "unprognostic (3.10e-2)" "unprognostic (7.97e-3)" "unprognostic (2.48e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (8.02e-8)" "unprognostic (1.97e-2)" "potential prognostic favorable (3.55e-4)" "validated prognostic unfavorable (1.04e-5)" "validated prognostic unfavorable (2.34e-4)" "unprognostic (6.60e-2)" "unprognostic (2.57e-1)" "unprognostic (4.72e-2)" "unprognostic (2.30e-1)" "unprognostic (2.33e-1)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.66e-1)" "unprognostic (2.87e-1)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (1.02e-1)" "unprognostic (3.16e-1)" "unprognostic (1.42e-1)" "unprognostic (5.00e-2)" "unprognostic (2.23e-1)" IDH3G ENSG00000067829 "Isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma" P51553 X 153785766-153794512 "Citric acid cycle related proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 443.8;Oocytes: 211.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 443.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 87265522.1" "Tissue enhanced" "Detected in all" "cerebral cortex: 38025810.2;heart muscle: 36706711.0" "HPA000425, HPA002017" Supported Approved "Nucleoli,Plasma membrane,Mitochondria" Yes No 9400 "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 10 "Nucleoli, Mitochondria" "Plasma membrane" "HPA000425: , HPA002017: " "unprognostic (2.31e-2)" "unprognostic (8.48e-3)" "unprognostic (2.95e-1)" "unprognostic (6.94e-2)" "unprognostic (1.03e-1)" "unprognostic (7.87e-3)" "unprognostic (1.89e-1)" "unprognostic (6.63e-3)" "unprognostic (2.08e-2)" "unprognostic (2.22e-3)" "unprognostic (4.52e-3)" "unprognostic (2.61e-1)" "potential prognostic favorable (1.31e-6)" "unprognostic (1.26e-2)" "unprognostic (5.57e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (1.55e-1)" "unprognostic (7.42e-2)" "unprognostic (1.25e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-2)" "unprognostic (1.70e-1)" "unprognostic (4.62e-1)" "unprognostic (3.95e-1)" "unprognostic (1.76e-1)" "unprognostic (3.46e-2)" "unprognostic (2.31e-1)" "unprognostic (3.16e-1)" "unprognostic (1.50e-1)" "unprognostic (9.51e-2)" IDO1 "IDO, INDO" ENSG00000131203 "Indoleamine 2,3-dioxygenase 1" P14902 8 39902275-39928790 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.0;placenta: 104.2" "Cell type enhanced" "Detected in some" "cDC: 109.7;Endometrial ciliated cells: 46.6;Endometrial glandular cells: 365.3;Endometrial luminal cells: 314.5;Endometrial secretory cells: 67.1;Epididymal basal cells: 75.8" "Cell type enhanced" "Detected in many" "dendritic cells: 109.7;Glandular cells: 365.3;Luminal cells: 314.5" "Cell type enhanced" "Detected in some" "leukocyte: 3.0;lower rhombic lip: 1.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 14 "eosinophil: 465.9" "Lineage enriched" "Detected in many" 18 "granulocytes: 465.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 15.4" "Adipose subcutaneous - T-cells, Kidney - T-cells, Skeletal muscle - Skeletal myocytes, Spleen - T-cells" "Region enriched" "Detected in many" 12 "basal ganglia: 34.1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 11286419.2;Microglia and Neuropil: 6848653.4" "Tissue enriched" "Detected in many" "heart muscle: 8730170.7" "HPA023072, HPA023149, HPA027772, CAB072820" Enhanced Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 1 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "CAB072820: , HPA023072: , HPA023149: , HPA027772: " "unprognostic (6.47e-2)" "unprognostic (3.04e-2)" "unprognostic (2.03e-1)" "unprognostic (8.61e-2)" "unprognostic (1.72e-1)" "unprognostic (8.76e-3)" "unprognostic (1.74e-1)" "unprognostic (2.37e-1)" "unprognostic (4.36e-3)" "unprognostic (1.73e-1)" "unprognostic (2.09e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (2.66e-1)" "unprognostic (1.43e-2)" "unprognostic (3.54e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (2.53e-1)" "unprognostic (9.08e-3)" "unprognostic (2.69e-1)" "unprognostic (4.00e-2)" "unprognostic (3.14e-2)" "unprognostic (2.02e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (2.20e-3)" "unprognostic (9.41e-2)" "unprognostic (5.36e-2)" "unprognostic (6.17e-2)" "unprognostic (4.03e-2)" IDO2 INDOL1 ENSG00000188676 "Indoleamine 2,3-dioxygenase 2" Q6ZQW0 8 39934614-40016392 "Metabolic proteins, Predicted intracellular proteins" "Immunity, Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "liver: 3.1;placenta: 5.2" "Group enriched" "Detected in some" 4 "Endometrial glandular cells: 245.6;Endometrial luminal cells: 316.5" "Group enriched" "Detected in many" 4 "Glandular cells: 245.6;Luminal cells: 316.5" "Cell type enriched" "Detected in some" 6 "lower rhombic lip: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Spleen - T-cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA054911 Approved Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" Cytosol "HPA054911: " "unprognostic (6.62e-2)" "potential prognostic favorable (1.96e-4)" IFI16 "IFNGIP1, PYHIN2" ENSG00000163565 "Interferon gamma inducible protein 16" Q16666 1 158999968-159055155 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 601.2;Hofbauer cells: 412.5;Microglia: 411.3;Neutrophils: 683.1;Vascular endothelial cells: 470.4" "Cell type enhanced" "Detected in all" "Neutrophils: 683.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 504.5;endothelial cell: 198.1;leukocyte: 347.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Skeletal muscle - Endothelial cells" "Cell type enhanced" "Detected in all" "B-cells: 87352237.0;T-cells: 65580079.5" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127978296.2" "HPA002134, CAB016293, HPA073514" Enhanced Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 154 "Nucleoplasm, Nucleoli" Cytosol "CAB016293: , HPA002134: , HPA073514: " "unprognostic (6.91e-2)" "unprognostic (9.73e-2)" "unprognostic (1.77e-1)" "unprognostic (3.15e-1)" "unprognostic (2.20e-1)" "unprognostic (1.80e-1)" "unprognostic (2.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (2.83e-1)" "unprognostic (2.43e-3)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (6.16e-5)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (1.77e-1)" "unprognostic (6.23e-2)" "unprognostic (1.69e-1)" "unprognostic (2.03e-2)" "unprognostic (1.18e-2)" "unprognostic (5.29e-2)" "unprognostic (1.27e-1)" "unprognostic (5.58e-2)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (2.00e-1)" "unprognostic (3.69e-1)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" IFI27L2 "FAM14A, TLH29" ENSG00000119632 "Interferon alpha inducible protein 27 like 2" Q9H2X8 14 94127779-94130253 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 257.0;Megakaryocytes: 513.1;Melanocytes: 250.0;Platelets: 395.4" "Cell type enhanced" "Detected in many" "Megakaryocytes: 513.1;Platelets: 395.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA049588 Approved Nucleoli,Cytosol "Intracellular and membrane" Other No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 47: Platelets - Hemostasis" Cytosol Nucleoli "HPA049588: " "unprognostic (2.05e-2)" "unprognostic (1.56e-2)" "unprognostic (2.11e-2)" "unprognostic (3.32e-2)" "unprognostic (4.65e-2)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (2.20e-1)" "unprognostic (2.31e-3)" "unprognostic (5.06e-1)" "unprognostic (6.91e-2)" "unprognostic (9.16e-2)" "unprognostic (8.86e-2)" "unprognostic (6.00e-3)" "unprognostic (2.56e-1)" "unprognostic (5.44e-2)" "unprognostic (1.41e-1)" "unprognostic (2.60e-2)" "unprognostic (8.05e-2)" "unprognostic (5.03e-2)" "unprognostic (1.93e-1)" "unprognostic (3.51e-2)" "unprognostic (1.13e-1)" "unprognostic (2.70e-2)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (3.17e-1)" "unprognostic (2.24e-1)" "unprognostic (3.68e-1)" "unprognostic (1.46e-1)" "unprognostic (2.40e-2)" IFIT1 "G10P1, GARG-16, IFI56, IFNAI1" ENSG00000185745 "Interferon induced protein with tetratricopeptide repeats 1" P09914 10 89392546-89406487 "Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 63.4;Epididymal efferent duct ciliated cells: 64.2;Hofbauer cells: 61.3;Müller glia: 76.1" "Cell type enhanced" "Detected in many" "Glial cells: 76.1" "Cell type enhanced" "Detected in all" "endothelial cell: 106.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 67.0" "Group enriched" "Detected in all" 8 "granulocytes: 67.0;monocytes: 21.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 11615185.9" "Low tissue specificity" "Detected in all" "CAB045980, HPA053890, HPA055380, CAB080338" Supported Enhanced Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 10 Cytosol "CAB045980: , CAB080338: , HPA053890: , HPA055380: " "unprognostic (1.20e-1)" "unprognostic (4.71e-2)" "unprognostic (2.18e-2)" "unprognostic (1.69e-1)" "unprognostic (4.93e-2)" "unprognostic (8.93e-2)" "unprognostic (4.72e-3)" "unprognostic (1.80e-2)" "unprognostic (2.12e-2)" "unprognostic (1.16e-1)" "potential prognostic favorable (3.60e-6)" "unprognostic (3.36e-2)" "potential prognostic favorable (2.60e-4)" "unprognostic (1.09e-1)" "unprognostic (4.46e-3)" "unprognostic (1.74e-1)" "unprognostic (1.65e-2)" "unprognostic (2.32e-1)" "unprognostic (2.73e-1)" "unprognostic (1.16e-1)" "unprognostic (9.48e-2)" "unprognostic (9.89e-3)" "unprognostic (2.61e-3)" "unprognostic (1.85e-1)" "unprognostic (5.09e-1)" "unprognostic (2.18e-3)" "unprognostic (2.00e-1)" "unprognostic (8.91e-3)" "unprognostic (6.69e-2)" "unprognostic (1.08e-1)" "unprognostic (3.32e-2)" IFRD1 "PC4, TIS7" ENSG00000006652 "Interferon related developmental regulator 1" O00458 7 112422887-112481017 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 54.0" "Cell type enhanced" "Detected in many" "Astrocytes: 82.0;Bergmann glia: 57.0;Brain excitatory neurons: 49.4;Choroid plexus epithelial cells: 100.0;Distal convoluted tubule cells: 65.3;Early spermatids: 108.6;Ependymal cells: 66.9;Loop of henle epithelial cells: 72.6;Microglia: 83.4;Neutrophils: 51.0;Oligodendrocytes: 49.9;Other brain neurons: 45.0;Podocytes: 49.6;Proximal tubule cells: 59.1;Renal collecting duct intercalated cells: 71.8;Renal collecting duct principal cells: 45.5;Renal connecting tubule cells: 77.4;Sertoli cells: 52.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 100.0;Ductal cells: 77.4;Glial cells: 83.4;Renal nephron cells: 72.6;Spermatogenic cell types: 108.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 64.3;neutrophil: 112.7" "Lineage enriched" "Detected in all" 13 "granulocytes: 112.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 173650.8;T-cells: 202388.6" "Group enriched" "Detected in some" "lymphoid tissue: 90961.3;pancreas: 193332.2" "HPA024122, HPA072413" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 2 "Plasma membrane" "Endoplasmic reticulum, Cytosol" "HPA024122: , HPA072413: " "unprognostic (1.22e-1)" "unprognostic (7.50e-2)" "unprognostic (5.63e-2)" "unprognostic (4.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.24e-1)" "unprognostic (9.35e-2)" "unprognostic (1.53e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (1.43e-4)" "unprognostic (5.36e-3)" "unprognostic (5.55e-2)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (2.47e-2)" "unprognostic (4.07e-2)" "unprognostic (1.04e-1)" "unprognostic (2.42e-1)" "unprognostic (3.42e-1)" "unprognostic (6.46e-2)" "unprognostic (1.28e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (6.73e-5)" "unprognostic (4.18e-2)" "unprognostic (2.60e-2)" "unprognostic (4.56e-2)" "unprognostic (1.95e-2)" "unprognostic (1.82e-1)" "unprognostic (8.00e-2)" "unprognostic (6.25e-2)" "unprognostic (1.35e-1)" IFT122 "FAP80, SPG, WDR10, WDR10p, WDR140" ENSG00000163913 "Intraflagellar transport 122" Q9HBG6 3 129429607-129520510 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 44.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 275.9;Early primary spermatocytes: 212.7;Early spermatids: 175.7;Ependymal cells: 152.2;Late primary spermatocytes: 164.0;Late spermatids: 231.4" "Cell type enhanced" "Detected in all" "Myocytes: 275.9;Spermatogenic cell types: 231.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 14215173.4" "Tissue enhanced" "Detected in many" "intestine: 4132905.3" HPA041815 Uncertain Approved "Primary cilium transition zone,Cytosol,Mid piece,Principal piece" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 25 "Primary cilium transition zone, Cytosol, Mid piece" "Principal piece" "HPA041815: " "unprognostic (2.08e-1)" "unprognostic (6.84e-2)" "unprognostic (6.23e-2)" "unprognostic (5.79e-2)" "unprognostic (2.11e-1)" "unprognostic (2.52e-1)" "unprognostic (4.49e-1)" "unprognostic (1.62e-1)" "unprognostic (2.25e-2)" "unprognostic (1.25e-1)" "validated prognostic favorable (2.53e-7)" "validated prognostic favorable (6.15e-4)" "unprognostic (8.78e-2)" "unprognostic (7.21e-2)" "unprognostic (1.68e-1)" "unprognostic (8.45e-2)" "unprognostic (4.39e-3)" "unprognostic (1.65e-1)" "unprognostic (4.33e-1)" "unprognostic (1.68e-1)" "unprognostic (7.82e-2)" "unprognostic (1.76e-1)" "unprognostic (4.59e-2)" "unprognostic (6.95e-2)" "unprognostic (1.44e-2)" "unprognostic (2.79e-1)" "unprognostic (5.44e-2)" "unprognostic (1.95e-1)" "unprognostic (2.77e-1)" "unprognostic (7.47e-2)" "unprognostic (1.42e-1)" IFT20 ENSG00000109083 "Intraflagellar transport 20" Q8IY31 17 28328325-28335489 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 212.5;Early spermatids: 254.5;Late primary spermatocytes: 245.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 254.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 1362979.0" "Group enriched" "Detected in many" "fallopian tube: 933788.4;Stomach: 2134185.6" HPA021376 Approved Approved "Microtubules,Mitotic spindle,Primary cilium,Basal body,Flagellar centriole,Mid piece,Principal piece,End piece" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 8: Pancreas - Proteolysis" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 73 "Microtubules, Primary cilium" "Mitotic spindle, Basal body, Flagellar centriole, Mid piece, Principal piece, End piece" "HPA021376: " "unprognostic (8.31e-2)" "unprognostic (1.17e-1)" "unprognostic (3.52e-1)" "unprognostic (1.72e-2)" "unprognostic (1.13e-1)" "unprognostic (2.30e-2)" "unprognostic (3.64e-3)" "unprognostic (1.11e-1)" "unprognostic (5.92e-3)" "unprognostic (4.53e-2)" "unprognostic (1.88e-3)" "unprognostic (9.09e-2)" "unprognostic (2.89e-1)" "validated prognostic unfavorable (8.10e-5)" "validated prognostic unfavorable (2.36e-4)" "unprognostic (2.48e-1)" "unprognostic (7.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.48e-1)" "unprognostic (2.28e-1)" "unprognostic (5.16e-2)" "unprognostic (3.09e-3)" "unprognostic (4.46e-2)" "unprognostic (1.63e-2)" "unprognostic (4.64e-2)" "unprognostic (1.45e-1)" "unprognostic (3.32e-3)" "unprognostic (7.14e-3)" "unprognostic (6.85e-2)" "unprognostic (4.65e-2)" "unprognostic (2.01e-2)" IFT22 "DKFZp761N0823, FAP9, FLJ13225, FLJ14117, RABL5" ENSG00000128581 "Intraflagellar transport 22" Q9H7X7 7 101310914-101321823 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 69.9" "Cell type enhanced" "Detected in many" "Early spermatids: 521.4;Epididymal efferent duct ciliated cells: 293.0;Fallopian tube ciliated cells: 310.8;Late primary spermatocytes: 776.8;Late spermatids: 2180.3;Respiratory ciliated cells: 286.8" "Cell type enriched" "Detected in many" 7 "Spermatogenic cell types: 2180.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 3241668.8" "Group enriched" "Detected in many" "fallopian tube: 5902479.6;lung: 4929654.3" HPA042930 Approved Approved "Microtubules,Mitotic spindle,Primary cilium,Basal body,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 56 "Microtubules, Cytosol" "Mitotic spindle, Primary cilium, Basal body, Flagellar centriole, Mid piece, Principal piece, End piece" "HPA042930: " "unprognostic (1.15e-1)" "unprognostic (2.27e-1)" "unprognostic (1.52e-1)" "unprognostic (2.77e-2)" "unprognostic (1.75e-1)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (6.35e-5)" "unprognostic (4.28e-2)" "unprognostic (2.56e-2)" "unprognostic (1.68e-1)" "unprognostic (7.40e-2)" "unprognostic (7.38e-3)" "unprognostic (2.80e-3)" "unprognostic (1.92e-1)" "unprognostic (1.66e-2)" "unprognostic (1.68e-1)" "unprognostic (1.62e-1)" "unprognostic (1.48e-1)" "unprognostic (3.83e-1)" "unprognostic (2.14e-1)" "unprognostic (2.51e-1)" "unprognostic (1.46e-3)" "unprognostic (9.95e-2)" "unprognostic (2.00e-1)" "unprognostic (2.12e-2)" "unprognostic (7.32e-2)" "unprognostic (3.37e-2)" "unprognostic (3.62e-1)" "unprognostic (2.75e-3)" IFT43 "C14orf179, FLJ32173, MGC16028" ENSG00000119650 "Intraflagellar transport 43" Q96FT9 14 75902136-76084585 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fallopian tube ciliated cells: 383.0;Respiratory ciliated cells: 366.2" "Cell type enhanced" "Detected in all" "Ciliated cells: 383.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 2545844.7" "Tissue enriched" "Detected in single" 22081 "fallopian tube: 2208052.3" HPA003438 Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body,Perinuclear theca,Principal piece,End piece" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 107: Ciliated cells - Cilia assembly & function" 27 "Microtubules, Primary cilium, Principal piece, End piece" "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Basal body, Perinuclear theca" "HPA003438: " "unprognostic (2.40e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (7.64e-4)" "unprognostic (7.14e-2)" "unprognostic (3.95e-2)" "unprognostic (7.25e-2)" "unprognostic (2.13e-1)" "unprognostic (2.56e-2)" "unprognostic (1.31e-3)" "unprognostic (2.43e-2)" "unprognostic (2.83e-1)" "unprognostic (3.52e-3)" "unprognostic (4.27e-3)" "unprognostic (8.21e-3)" "unprognostic (1.44e-1)" "unprognostic (9.22e-2)" "unprognostic (9.15e-2)" "unprognostic (3.26e-1)" "unprognostic (1.17e-1)" "unprognostic (2.03e-1)" "unprognostic (4.80e-2)" "unprognostic (7.82e-2)" "unprognostic (3.53e-1)" "unprognostic (6.32e-2)" "unprognostic (2.26e-1)" "unprognostic (1.55e-1)" "unprognostic (5.41e-2)" "unprognostic (5.79e-2)" "unprognostic (1.85e-1)" "unprognostic (4.58e-2)" IFT52 "C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5" ENSG00000101052 "Intraflagellar transport 52" Q9Y366 20 43590937-43647299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 8167492.4" "Group enriched" "Detected in some" 10293 "fallopian tube: 1601891.1;lymphoid tissue: 456769.6" "HPA063367, HPA067423" Enhanced Approved "Microtubules,Primary cilium,Basal body,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 107: Ciliated cells - Cilia assembly & function" 37 Microtubules "Primary cilium, Basal body, Cytosol" "HPA063367: , HPA067423: " "unprognostic (3.92e-2)" "unprognostic (1.20e-2)" "unprognostic (3.03e-1)" "unprognostic (4.48e-2)" "unprognostic (3.32e-1)" "unprognostic (5.27e-2)" "unprognostic (1.10e-1)" "unprognostic (5.51e-2)" "unprognostic (1.11e-1)" "unprognostic (2.95e-3)" "potential prognostic favorable (7.61e-6)" "unprognostic (2.22e-1)" "unprognostic (8.72e-2)" "potential prognostic unfavorable (5.11e-5)" "unprognostic (1.60e-2)" "unprognostic (6.16e-2)" "unprognostic (5.18e-2)" "unprognostic (1.96e-1)" "unprognostic (3.26e-1)" "unprognostic (2.32e-1)" "unprognostic (4.67e-3)" "unprognostic (6.47e-2)" "unprognostic (9.32e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (5.54e-3)" "unprognostic (1.32e-1)" "unprognostic (1.29e-1)" "unprognostic (9.38e-2)" "unprognostic (4.97e-2)" "unprognostic (2.41e-1)" IFT57 "ESRRBL1, FLJ10147, HIPPI, MHS4R2" ENSG00000114446 "Intraflagellar transport 57" Q9NWB7 3 108160812-108222435 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" DNA-binding Ciliopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1871.3;Epididymal efferent duct ciliated cells: 472.6;Fallopian tube ciliated cells: 599.9;Late primary spermatocytes: 901.9;Late spermatids: 3984.0;Respiratory ciliated cells: 798.6;Transitional alveolar cells: 526.5" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 3984.0" "Cell type enhanced" "Detected in all" "ependymal cell: 155.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 42.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 7301922.4" "Tissue enriched" "Detected in some" "pancreas: 24300031.3" "HPA035514, HPA035515" Supported Approved "Golgi apparatus,Primary cilium,Primary cilium transition zone,Centriolar satellite,Basal body,Cytosol,Mid piece" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 68 "Golgi apparatus, Primary cilium, Basal body, Mid piece" "Primary cilium transition zone, Centriolar satellite, Cytosol" "HPA035514: , HPA035515: " "unprognostic (1.45e-1)" "unprognostic (4.99e-2)" "unprognostic (9.08e-2)" "unprognostic (4.94e-2)" "unprognostic (6.45e-2)" "unprognostic (2.96e-3)" "unprognostic (3.02e-2)" "unprognostic (2.07e-2)" "unprognostic (2.96e-2)" "unprognostic (5.29e-2)" "potential prognostic favorable (1.88e-4)" "unprognostic (6.14e-2)" "unprognostic (5.89e-2)" "unprognostic (2.21e-2)" "unprognostic (1.91e-2)" "unprognostic (3.98e-2)" "unprognostic (1.56e-1)" "unprognostic (1.50e-2)" "unprognostic (1.05e-1)" "unprognostic (2.14e-2)" "unprognostic (1.47e-2)" "unprognostic (6.75e-2)" "unprognostic (2.60e-1)" "unprognostic (4.99e-1)" "unprognostic (4.28e-2)" "unprognostic (3.02e-1)" "unprognostic (3.63e-2)" "unprognostic (1.38e-1)" "unprognostic (1.50e-1)" "unprognostic (7.87e-2)" "unprognostic (2.03e-2)" IFT81 "CDV-1R, CDV1, MGC4027" ENSG00000122970 "Intraflagellar transport 81" Q8WYA0 12 110124335-110218793 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 184.2;Early primary spermatocytes: 243.9;Ependymal cells: 194.2;Fallopian tube ciliated cells: 218.9;Respiratory ciliated cells: 287.7" "Cell type enhanced" "Detected in all" "Ciliated cells: 287.7;Spermatogenic cell types: 243.9" "Cell type enhanced" "Detected in all" "ependymal cell: 215.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 12817270.1" "Tissue enriched" "Detected in some" "fallopian tube: 4863795.4" "HPA019087, HPA020051" Enhanced Approved "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 45 Cytosol "Primary cilium, Centrosome, Basal body" "HPA019087: , HPA020051: " "unprognostic (7.85e-2)" "unprognostic (3.80e-1)" "unprognostic (1.42e-1)" "unprognostic (7.95e-3)" "unprognostic (1.12e-1)" "unprognostic (7.45e-2)" "unprognostic (1.33e-1)" "unprognostic (1.58e-1)" "unprognostic (3.00e-2)" "unprognostic (5.72e-3)" "unprognostic (4.25e-2)" "unprognostic (9.13e-2)" "unprognostic (7.60e-2)" "unprognostic (8.19e-2)" "unprognostic (1.91e-1)" "unprognostic (2.52e-1)" "unprognostic (3.05e-1)" "unprognostic (2.07e-1)" "unprognostic (5.49e-2)" "unprognostic (7.19e-2)" "unprognostic (1.31e-1)" "unprognostic (2.88e-2)" "unprognostic (3.28e-2)" "unprognostic (2.80e-2)" "unprognostic (3.35e-2)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (1.35e-2)" "unprognostic (2.86e-1)" "unprognostic (6.04e-2)" "unprognostic (3.10e-1)" IFT88 "D13S1056E, hTg737, MGC26259, Tg737, TTC10" ENSG00000032742 "Intraflagellar transport 88" Q13099 13 20567138-20691444 "Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 65.5" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 375.3;Ependymal cells: 505.2;Late primary spermatocytes: 332.7;Respiratory ciliated cells: 454.2;Rod photoreceptor cells: 390.2" "Cell type enhanced" "Detected in all" "Ciliated cells: 505.2;Neuronal cells: 390.2;Spermatogenic cell types: 375.3" "Cell type enhanced" "Detected in all" "ependymal cell: 558.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 19746931.4" "Group enriched" "Detected in some" "fallopian tube: 1811302.7;ovary: 5194437.6" HPA078625 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body,Connecting piece,Mid piece,Principal piece,End piece" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 49 "Microtubules, Primary cilium, End piece" "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Basal body, Connecting piece, Mid piece, Principal piece" "HPA078625: " "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (9.64e-2)" "unprognostic (3.20e-2)" "unprognostic (2.32e-1)" "unprognostic (4.87e-2)" "unprognostic (1.33e-1)" "unprognostic (2.92e-1)" "unprognostic (4.58e-1)" "unprognostic (1.80e-3)" "validated prognostic favorable (2.29e-9)" "validated prognostic favorable (3.10e-4)" "unprognostic (8.55e-3)" "unprognostic (1.45e-1)" "unprognostic (2.19e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-1)" "unprognostic (3.94e-2)" "unprognostic (1.41e-1)" "unprognostic (1.29e-1)" "unprognostic (1.12e-1)" "unprognostic (8.96e-3)" "unprognostic (5.54e-3)" "unprognostic (2.44e-1)" "unprognostic (2.58e-2)" "unprognostic (3.67e-1)" "unprognostic (2.44e-2)" "unprognostic (1.46e-1)" "unprognostic (9.63e-2)" "unprognostic (1.89e-1)" "unprognostic (6.09e-2)" IGBP1 "alpha4, IBP1" ENSG00000089289 "Immunoglobulin binding protein 1" P78318 X 70133447-70166324 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "B-cell activation" Chaperone "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 341.3;Esophageal apical cells: 337.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA000634, HPA001004, CAB034139" Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes NA 34000 "Cluster 31: T-cells - T-cell receptor" "Cluster 54: Non-specific - Ribosome" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 47 "Microtubules, Primary cilium" "Cytokinetic bridge, Basal body" "CAB034139: , HPA000634: , HPA001004: " "unprognostic (1.23e-1)" "unprognostic (2.75e-1)" "unprognostic (5.27e-1)" "unprognostic (9.20e-3)" "unprognostic (4.48e-1)" "unprognostic (2.90e-1)" "unprognostic (2.02e-3)" "unprognostic (5.46e-2)" "unprognostic (8.29e-3)" "unprognostic (3.79e-1)" "validated prognostic favorable (3.38e-10)" "validated prognostic favorable (6.10e-4)" "unprognostic (5.63e-2)" "unprognostic (3.75e-3)" "potential prognostic unfavorable (7.16e-5)" "unprognostic (5.66e-1)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (2.24e-2)" "unprognostic (2.07e-2)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (9.06e-2)" "unprognostic (3.09e-1)" "unprognostic (3.05e-1)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (2.05e-1)" "unprognostic (1.48e-1)" "unprognostic (6.12e-2)" "unprognostic (8.45e-3)" "unprognostic (3.88e-2)" IGBP1P2 ENSG00000266826 "Immunoglobulin (CD79A) binding protein 1 pseudogene 2" 17 58660424-58692045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Tissue enriched" "Detected in single" 32 "testis: 8.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "HPA000634, HPA001004" Uncertain Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Microtubules, Primary cilium" "Cytokinetic bridge, Basal body" "HPA000634: , HPA001004: " IGF1R "CD221, IGFIR, IGFR, JTK13, MGC18216" ENSG00000140443 "Insulin like growth factor 1 receptor" P08069 15 98648539-98964530 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Host-virus interaction" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 2488.0;Podocytes: 1295.1;Proximal tubule cells: 1339.2" "Cell type enhanced" "Detected in many" "Neutrophils: 2488.0" "Cell type enhanced" "Detected in all" "endothelial cell: 1591.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 4.3;T-cells: 1.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 792421.3;Pancreatic islets: 673759.3" "Tissue enhanced" "Detected in many" "lung: 1257116.6" "HPA004822, CAB010268, HPA045563" Approved Approved "Nucleoli,Nucleoli rim,Plasma membrane,Primary cilium" NA NA 6800 "Cluster 35: Neutrophils - Protein binding" "Cluster 8: Pancreas - Proteolysis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 128 "Nucleoli, Plasma membrane" "Nucleoli rim, Primary cilium" "CAB010268: , HPA004822: , HPA045563: " "unprognostic (1.45e-2)" "unprognostic (2.28e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (4.03e-5)" "unprognostic (1.43e-1)" "unprognostic (9.27e-3)" "unprognostic (4.46e-2)" "unprognostic (3.08e-1)" "validated prognostic favorable (3.89e-9)" "validated prognostic favorable (2.90e-4)" "unprognostic (1.95e-1)" "unprognostic (4.72e-2)" "unprognostic (5.61e-2)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (1.75e-1)" "unprognostic (1.07e-1)" "unprognostic (1.66e-2)" "unprognostic (3.49e-1)" "unprognostic (8.00e-2)" "unprognostic (2.97e-2)" "unprognostic (2.84e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-2)" "unprognostic (5.71e-2)" "unprognostic (2.20e-1)" "unprognostic (3.04e-1)" "unprognostic (6.77e-2)" "unprognostic (4.48e-3)" IGF2 "C11orf43, FLJ44734, IGF-II" ENSG00000167244 "Insulin like growth factor 2" P01344 11 2129112-2158391 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Carbohydrate metabolism, Glucose metabolism, Osteogenesis" "Growth factor, Hormone, Mitogen" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "placenta: 2597.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 92.5;Extravillous trophoblasts: 411.3;Fibroblasts: 56.2;Leydig cells: 138.2;Migrating cytotrophoblasts: 149.7;Syncytiotrophoblasts: 148.5;Thymic myoid cells: 304.6" "Group enriched" "Detected in some" 5 "Leydig cells: 138.2;Stromal cells: 304.6;Trophoblast cells: 411.3" "Group enriched" "Detected in some" 11 "fibroblast: 396.0;pericyte: 307.1;vascular associated smooth muscle cell: 105.5" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 958.2;Ovary Serous Cystadenocarcinoma (TCGA): 1031.2" "Region enhanced" "Detected in all" "choroid plexus: 618.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 597.2;Sarcoma: 625.3" "Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 586 "Proximal tubules: 58560.3" "Tissue enriched" "Detected in single" 13075 "ovary: 1307501.2" HPA007556 Enhanced Approved "Golgi apparatus" "Secreted to blood" Hormone NA NA 609000000 520000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 9 "Golgi apparatus" "HPA007556: " "unprognostic (3.37e-2)" "unprognostic (3.48e-1)" "unprognostic (1.18e-1)" "unprognostic (3.61e-2)" "unprognostic (2.42e-1)" "unprognostic (3.21e-1)" "unprognostic (6.18e-3)" "unprognostic (2.77e-1)" "unprognostic (1.19e-1)" "unprognostic (2.28e-1)" "unprognostic (1.65e-2)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (2.28e-4)" "unprognostic (2.63e-3)" "unprognostic (5.39e-3)" "unprognostic (6.87e-2)" "unprognostic (4.74e-2)" "unprognostic (1.98e-1)" "unprognostic (2.09e-1)" "unprognostic (8.07e-3)" "potential prognostic unfavorable (4.85e-5)" "unprognostic (4.61e-2)" "unprognostic (1.30e-3)" "unprognostic (1.47e-1)" "unprognostic (1.64e-2)" "unprognostic (3.77e-2)" "unprognostic (7.35e-2)" "unprognostic (8.22e-3)" "unprognostic (2.04e-1)" "unprognostic (2.00e-2)" "unprognostic (2.75e-1)" IGFBP1 "AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12" ENSG00000146678 "Insulin like growth factor binding protein 1" P08833 7 45888360-45893660 "Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Growth factor binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "liver: 1120.5" "Group enriched" "Detected in some" 17 "Decidual stromal cells: 1196.6;Hepatocytes: 1209.6" "Group enriched" "Detected in many" 27 "Hepatocytes: 1209.6;Stromal cells: 1196.6" "Cell type enhanced" "Detected in single" "lower rhombic lip: 1.1" "Cancer enriched" "Detected in many" 16 "Liver Hepatocellular Carcinoma (TCGA): 538.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 38.2;liver cancer: 75.4;ovarian cancer: 50.4" "Adipose visceral - Mesothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004445, HPA046972, HPA050640" Enhanced Approved "Golgi apparatus" "Secreted to blood" Other NA NA 28100000 27000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 93: Hepatocytes - Bile production & excretion" 4 "Golgi apparatus" "CAB004445: , HPA046972: , HPA050640: " "unprognostic (1.57e-2)" "unprognostic (1.31e-1)" "unprognostic (3.22e-3)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (9.24e-7)" "unprognostic (5.58e-3)" "unprognostic (8.89e-2)" "unprognostic (8.70e-2)" "unprognostic (3.44e-1)" "potential prognostic unfavorable (2.02e-4)" "unprognostic (1.12e-1)" "unprognostic (9.01e-2)" "potential prognostic unfavorable (5.59e-7)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (5.35e-2)" IGFN1 "DKFZp434B1231, EEF1A2BP1" ENSG00000163395 "Immunoglobulin like and fibronectin type III domain containing 1" Q86VF2 1 201190824-201228952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skeletal muscle: 174.5" "Cell type enhanced" "Detected in some" "Astrocytes: 21.6;Leydig cells: 47.1;Myonuclei: 81.7;Pancreatic acinar cells: 86.2;Peritubular myoid cells: 17.2;Thymic myoid cells: 295.0" "Cell type enhanced" "Detected in many" "Acinar cells: 86.2;Leydig cells: 47.1;Myocytes: 81.7;Stromal cells: 295.0" "Cell type enhanced" "Detected in some" "astrocyte: 23.6;choroid plexus epithelial cell: 12.0" "Group enriched" "Detected in some" 6 "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.0;Thyroid Carcinoma (TCGA): 9.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 180.0;Rhabdoid: 98.7" "Testis - Peritubular cells" "Group enriched" "Detected in many" 7 "amygdala: 3.3;basal ganglia: 1.2;cerebral cortex: 2.9;hippocampal formation: 1.9" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 13325 "Skeletal myofibers: 1332490.0" "Tissue enriched" "Detected in single" 65453 "skeletal muscle: 6545285.4" HPA050415 Enhanced Approved "Midbody ring" Yes NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 2 "Midbody ring" "HPA050415: " "unprognostic (6.63e-2)" "unprognostic (4.46e-2)" "validated prognostic unfavorable (2.09e-10)" "validated prognostic unfavorable (5.51e-4)" "unprognostic (8.08e-3)" "unprognostic (1.81e-2)" "unprognostic (1.99e-1)" IKZF3 "Aiolos, ZNFN1A3" ENSG00000161405 "IKAROS family zinc finger 3" Q9UKT9 17 39757718-39864312 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "B-cell activation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "intestine: 11.1;lymphoid tissue: 38.4" "Group enriched" "Detected in many" 7 "B-cells: 402.3;Mast cells: 165.0;NK-cells: 309.7;Plasma cells: 207.3;T-cells: 314.3" "Group enriched" "Detected in many" 7 "B-cells: 402.3;Mast cells: 165.0;NK-cells: 309.7;Plasma cells: 207.3;T-cells: 314.3" "Cell type enriched" "Detected in some" 48 "leukocyte: 417.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 13.2;T-cells: 28.8" "Group enriched" "Detected in some" 7 "lymphoma: 42.4;Myeloma: 33.3" "Adipose subcutaneous - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "B-cells: 10963563.5;T-cells: 7998358.2" "Group enriched" "Detected in some" 46020 "bone marrow: 2187787.9;intestine: 3838329.4;lymphoid tissue: 7779746.9" "HPA024377, HPA073266" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 157 Nucleoplasm Cytosol "HPA024377: , HPA073266: " "potential prognostic favorable (8.02e-4)" "unprognostic (2.12e-2)" "unprognostic (7.81e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-1)" "unprognostic (4.10e-2)" "unprognostic (3.24e-1)" "unprognostic (1.06e-3)" "unprognostic (1.48e-1)" "unprognostic (2.41e-1)" "unprognostic (2.28e-2)" "potential prognostic favorable (8.07e-5)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" "unprognostic (1.22e-1)" "unprognostic (4.22e-2)" "unprognostic (7.62e-2)" "unprognostic (9.32e-3)" "unprognostic (2.34e-1)" "unprognostic (1.23e-3)" "unprognostic (6.44e-2)" "unprognostic (3.89e-2)" "unprognostic (1.44e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (9.58e-2)" IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 54.5;lymphoid tissue: 71.6" "Cell type enhanced" "Detected in many" "cDC: 186.9;Extravillous trophoblasts: 162.3;Hofbauer cells: 83.9;Kupffer cells: 342.3;Macrophages: 166.4;Microglia: 94.5;monocytes: 232.6;Neutrophils: 206.8;NK-cells: 87.3;pDCs: 108.8;Plasma cells: 87.3;T-cells: 113.9" "Cell type enhanced" "Detected in many" "dendritic cells: 186.9;Mononuclear phagocytes: 342.3;Neutrophils: 206.8;T-cells: 113.9;Trophoblast cells: 162.3" "Group enriched" "Detected in many" 32 "central nervous system macrophage: 125.7;leukocyte: 186.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 28.7;Myeloma: 13.1" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Skeletal muscle - Macrophages, Skin - T-cells, Testis - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA065647, HPA069086" Supported "Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 30 "Plasma membrane, Cytosol" "Primary cilium" "HPA065647: , HPA069086: " "unprognostic (4.85e-2)" "unprognostic (3.46e-2)" "unprognostic (3.32e-2)" "unprognostic (1.34e-2)" "unprognostic (1.01e-1)" "unprognostic (3.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.84e-2)" "unprognostic (5.03e-3)" "unprognostic (3.33e-1)" "unprognostic (9.06e-2)" "unprognostic (3.28e-1)" "unprognostic (1.79e-1)" "unprognostic (1.26e-1)" "unprognostic (2.16e-2)" "unprognostic (3.93e-3)" "unprognostic (8.50e-2)" "unprognostic (1.17e-1)" "unprognostic (4.22e-1)" "unprognostic (5.63e-2)" "unprognostic (1.57e-1)" "unprognostic (2.80e-2)" "unprognostic (1.32e-1)" "unprognostic (2.97e-1)" "unprognostic (1.14e-2)" "unprognostic (8.27e-2)" "unprognostic (1.04e-2)" "unprognostic (2.11e-1)" "unprognostic (4.26e-3)" "unprognostic (2.18e-1)" "unprognostic (2.53e-1)" IL18R1 "CD218a, IL-1Rrp, IL1RRP" ENSG00000115604 "Interleukin 18 receptor 1" Q13478 2 102311529-102398777 "CD markers, Enzymes, Plasma proteins, Predicted membrane proteins" "Inflammatory response" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 11.3" "Group enriched" "Detected in many" 8 "Mast cells: 1307.9;Neutrophils: 3312.5" "Group enriched" "Detected in many" 8 "Mast cells: 1307.9;Neutrophils: 3312.5" "Group enriched" "Detected in some" 6 "endothelial cell: 71.4;leukocyte: 89.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 45.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Neutrophils, Spleen - Neutrophils_2, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 8086664.5" "Group enriched" "Detected in some" 1512 "intestine: 178395.4;liver: 88505.7;lung: 194142.3;lymphoid tissue: 143805.9" HPA007615 Approved Approved Mitochondria Yes No "Cluster 15: NK-cells - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Mitochondria "HPA007615: " "potential prognostic favorable (1.88e-4)" "unprognostic (3.53e-1)" "unprognostic (6.53e-3)" "unprognostic (4.07e-2)" "potential prognostic favorable (7.74e-7)" "unprognostic (5.14e-2)" "unprognostic (7.94e-3)" "unprognostic (6.30e-2)" "unprognostic (2.99e-1)" "unprognostic (6.70e-2)" "unprognostic (1.17e-1)" "unprognostic (6.85e-3)" "unprognostic (3.33e-2)" "unprognostic (2.12e-1)" "unprognostic (3.25e-2)" "unprognostic (5.97e-3)" "unprognostic (1.30e-1)" "unprognostic (2.74e-2)" IL20RB "DIRS1, FNDC6, IL-20R2, MGC34923" ENSG00000174564 "Interleukin 20 receptor subunit beta" Q6UXL0 3 136946230-137011085 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "cervix: 58.4;esophagus: 121.1;skin 1: 165.8;vagina: 74.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 102.4;Early spermatids: 60.7;Esophageal apical cells: 547.3;Esophageal basal cells: 174.1;Esophageal suprabasal cells: 273.2;Ocular epithelial cells: 87.7;Suprabasal keratinocytes: 142.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 547.3;Basal cells: 174.1;Suprabasal cells: 273.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 87.7;Head and Neck Squamous Cell Carcinoma (TCGA): 80.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 56.6;head and neck cancer: 79.1" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA063914 Approved Vesicles,Cytosol NA NA "Cluster 58: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 14 Vesicles Cytosol "HPA063914: " "unprognostic (1.02e-2)" "unprognostic (2.36e-1)" "unprognostic (1.09e-1)" "unprognostic (2.14e-2)" "unprognostic (4.03e-1)" "validated prognostic unfavorable (2.22e-9)" "validated prognostic unfavorable (6.21e-4)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (4.57e-3)" "unprognostic (7.26e-2)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (4.61e-2)" "unprognostic (3.37e-2)" "unprognostic (1.73e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (1.67e-3)" "unprognostic (1.65e-1)" "unprognostic (4.56e-1)" "unprognostic (3.09e-3)" IL27RA "CRL1, IL-27R, TCCR, WSX-1, WSX1, zcytor1" ENSG00000104998 "Interleukin 27 receptor subunit alpha" Q6UWB1 19 14031762-14053218 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15.5" "Cell type enhanced" "Detected in some" "B-cells: 4.7;Brain excitatory neurons: 4.9;Ependymal cells: 8.1;Loop of henle epithelial cells: 4.4;monocytes: 3.7;NK-cells: 8.0;Other brain neurons: 4.9;Renal collecting duct intercalated cells: 3.8;Renal collecting duct principal cells: 4.6;T-cells: 6.7;Tuft cells: 11.5;Undifferentiated spermatogonia: 4.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 8.1;NK-cells: 8.0;Secretory gland support: 11.5" "Cell type enhanced" "Detected in many" "leukocyte: 44.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Spleen - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA073441 Approved Vesicles NA NA 150000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 102: Non-specific - Mixed function" 25 Vesicles "HPA073441: " "unprognostic (3.00e-1)" "potential prognostic favorable (9.04e-6)" "unprognostic (2.33e-2)" "unprognostic (1.52e-1)" "unprognostic (4.67e-2)" "unprognostic (2.30e-1)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (1.16e-1)" "unprognostic (2.70e-1)" "unprognostic (7.47e-2)" "unprognostic (5.89e-3)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (1.60e-2)" "unprognostic (6.03e-3)" "unprognostic (3.25e-1)" "unprognostic (2.36e-1)" "unprognostic (2.20e-2)" "unprognostic (7.30e-2)" "unprognostic (1.04e-1)" "unprognostic (3.14e-3)" "unprognostic (2.64e-1)" "unprognostic (2.42e-1)" "unprognostic (1.69e-2)" "unprognostic (2.09e-1)" "unprognostic (8.83e-2)" "unprognostic (1.16e-1)" "unprognostic (1.92e-1)" "unprognostic (2.48e-2)" "unprognostic (1.62e-2)" "unprognostic (1.31e-1)" "unprognostic (3.35e-1)" IL33 "C9orf26, DKFZp586H0523, DVS27, IL1F11, NF-HEV" ENSG00000137033 "Interleukin 33" O95760 9 6215786-6257983 "Predicted intracellular proteins, Predicted secreted proteins" Transcription Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 114.2" "Cell type enhanced" "Detected in many" "Astrocytes: 81.6;Bergmann glia: 70.5;Breast lactating cells: 91.7;Fibro-adipogenic progenitors: 65.4;Fibroblasts: 100.1;Gastric chief cells: 76.4;Lymphatic endothelial cells: 132.1;Medullary thymic epithelial cells: 127.2;Mucous neck cells: 128.4;Respiratory basal cells: 262.6;Respiratory secretory cells: 92.5;Vascular endothelial cells: 185.7" "Cell type enhanced" "Detected in many" "Basal cells: 262.6;Endothelial cells: 185.7;Gastric glandular cells: 128.4;Secretory gland support: 127.2" "Cell type enhanced" "Detected in some" "astrocyte: 86.9;Bergmann glia: 76.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "colorectal cancer: 24.6;Rhabdoid: 15.7;Sarcoma: 26.2;thyroid cancer: 8.9" "Adrenal gland - Endothelial cells, Heart muscle - Fibroblasts, Liver - Vascular endothelial cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 1055421.0" "Tissue enhanced" "Detected in many" "intestine: 5439206.6" "CAB007057, HPA022899, HPA024426" Supported Supported Nucleoplasm,Vesicles "Secreted to blood" Interleukin NA NA "Cluster 13: Lung - Secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 6 Nucleoplasm Vesicles "CAB007057: , HPA022899: , HPA024426: " "unprognostic (7.47e-3)" "unprognostic (1.17e-3)" "unprognostic (9.27e-3)" "unprognostic (1.13e-2)" "unprognostic (1.16e-2)" "unprognostic (1.41e-2)" "unprognostic (2.48e-1)" "unprognostic (5.28e-2)" "unprognostic (1.45e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (2.34e-5)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (3.70e-3)" "unprognostic (3.24e-3)" "potential prognostic favorable (4.43e-4)" "unprognostic (2.27e-2)" "unprognostic (2.53e-1)" "unprognostic (1.08e-1)" "unprognostic (1.75e-1)" "unprognostic (1.84e-1)" "unprognostic (2.63e-1)" "unprognostic (5.19e-2)" "unprognostic (1.51e-1)" "unprognostic (7.21e-2)" "unprognostic (9.60e-2)" "unprognostic (1.09e-1)" "unprognostic (1.43e-3)" "unprognostic (9.85e-2)" "unprognostic (9.30e-2)" "unprognostic (9.85e-2)" IL37 "FIL1, FIL1(ZETA), FIL1Z, IL-1F7, IL-1H4, IL-1RP1, IL1F7" ENSG00000125571 "Interleukin 37" Q9NZH6 2 112911165-112918882 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 114.2" "Cell type enhanced" "Detected in some" "Gastric chief cells: 1.1;Goblet cells: 1.3;Late spermatids: 3.1" "Cell type enhanced" "Detected in some" "Gastric glandular cells: 1.1;Goblet cells: 1.3;Spermatogenic cell types: 3.1" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Lung Adenocarcinoma (TCGA): 24.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.5" "Skin - Keratinocyte (granular)" "Cell type enriched" "Detected in single" 54240 "Keratinocytes: 5423964.2" "Tissue enriched" "Detected in all" "intestine: 28618938.5" "HPA045873, HPA054371, HPA057950" Uncertain Supported Nucleoplasm,Vesicles,Cytosol "Secreted to blood" Interleukin NA NA 76700 "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 6 "Nucleoplasm, Vesicles, Cytosol" "HPA045873: , HPA054371: , HPA057950: " "unprognostic (3.00e-3)" "unprognostic (3.57e-2)" "unprognostic (1.48e-2)" "unprognostic (4.00e-2)" "unprognostic (3.01e-1)" "unprognostic (1.68e-1)" "unprognostic (5.16e-2)" "unprognostic (4.14e-2)" "unprognostic (3.45e-1)" IL7R "CD127, IL7RA, lnc-IL7R" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 171.2" "Group enriched" "Detected in many" 5 "Innate lymphoid cells: 3240.4;T-cells: 1496.2" "Group enriched" "Detected in many" 10 "Innate lymphoid cells: 3240.4;T-cells: 1496.2" "Cell type enriched" "Detected in some" 115 "leukocyte: 454.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 102.3;MAIT T-cell: 370.2;memory CD4 T-cell: 214.4;memory CD8 T-cell: 151.1;naive CD4 T-cell: 180.0;naive CD8 T-cell: 125.1;NK-cell: 113.4" "Group enriched" "Detected in all" 34 "NK-cells: 113.4;T-cells: 370.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Colon - T-cells, Prostate - T-cells, Skin - T-cells, Stomach - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 1227 "T-cells: 122664.4" "Tissue enriched" "Detected in single" 348 "intestine: 34842.2" "CAB010215, HPA067550, CAB080603" Supported Supported "Plasma membrane" "Intracellular and membrane" Receptor NA NA 290000 "Cluster 27: T-cells - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 13 "Plasma membrane" "CAB010215: , CAB080603: , HPA067550: " "unprognostic (2.81e-1)" "unprognostic (5.36e-3)" "unprognostic (4.45e-2)" "unprognostic (6.91e-2)" "unprognostic (9.97e-2)" "unprognostic (3.73e-1)" "unprognostic (3.58e-2)" "unprognostic (1.17e-2)" "unprognostic (2.53e-1)" "unprognostic (1.38e-1)" "unprognostic (1.25e-1)" "unprognostic (1.04e-2)" "unprognostic (1.22e-1)" "unprognostic (6.18e-3)" "unprognostic (2.22e-2)" "unprognostic (2.20e-3)" "unprognostic (6.89e-2)" "unprognostic (6.82e-2)" "unprognostic (1.79e-1)" "unprognostic (8.32e-3)" "unprognostic (2.31e-1)" "unprognostic (1.92e-1)" "unprognostic (1.94e-2)" "unprognostic (3.92e-1)" "unprognostic (1.72e-2)" "unprognostic (2.01e-1)" "unprognostic (1.22e-1)" "unprognostic (1.68e-2)" "unprognostic (2.03e-2)" "unprognostic (8.41e-2)" "unprognostic (5.78e-2)" ILF2 NF45 ENSG00000143621 "Interleukin enhancer binding factor 2" Q12905 1 153661788-153671028 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 391.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 241635512.4" "Low tissue specificity" "Detected in all" "HPA007484, HPA072048" Supported Supported Nucleoplasm,Cytosol No No 1800000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 168 Nucleoplasm Cytosol "HPA007484: , HPA072048: " "unprognostic (1.10e-2)" "unprognostic (8.60e-3)" "unprognostic (2.19e-1)" "unprognostic (1.21e-1)" "unprognostic (2.24e-2)" "unprognostic (1.75e-2)" "unprognostic (3.87e-2)" "unprognostic (1.83e-2)" "unprognostic (3.11e-2)" "unprognostic (2.28e-3)" "unprognostic (2.40e-3)" "unprognostic (3.70e-1)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (9.59e-5)" "unprognostic (3.91e-3)" "unprognostic (8.48e-2)" "unprognostic (2.91e-2)" "unprognostic (2.30e-1)" "unprognostic (2.43e-1)" "unprognostic (1.45e-2)" "unprognostic (2.06e-1)" "unprognostic (6.12e-3)" "unprognostic (1.19e-1)" "unprognostic (5.71e-2)" "unprognostic (4.54e-2)" "unprognostic (3.15e-2)" "unprognostic (7.30e-2)" "unprognostic (2.47e-1)" "unprognostic (2.41e-1)" "unprognostic (1.02e-1)" "unprognostic (3.35e-1)" ILF3 "DRBP76, MPHOSPH4, MPP4, MPP4110, NF110, NF110b, NF90, NF90a, NF90c, NF90ctv, NFAR-1, NFAR-2, NFAR110, NFAR90, TCP110" ENSG00000129351 "Interleukin enhancer binding factor 3" Q12906 19 10654304-10692400 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, Transcription, Transcription regulation" "DNA-binding, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA001897 Supported Enhanced Nucleoplasm,Nucleoli,Mitochondria No No 2000000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 422 "Nucleoplasm, Nucleoli, Mitochondria" "HPA001897: " "unprognostic (1.73e-2)" "unprognostic (2.53e-1)" "unprognostic (8.14e-2)" "unprognostic (1.87e-3)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (2.14e-1)" "unprognostic (6.30e-3)" "unprognostic (4.18e-2)" "unprognostic (5.28e-3)" "potential prognostic favorable (8.93e-4)" "unprognostic (7.18e-2)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.39e-2)" "unprognostic (4.77e-3)" "unprognostic (1.27e-3)" "unprognostic (2.43e-1)" "unprognostic (4.94e-2)" "unprognostic (3.68e-2)" "unprognostic (5.52e-2)" "unprognostic (8.82e-2)" "unprognostic (7.75e-3)" "unprognostic (1.16e-1)" "unprognostic (4.30e-3)" "unprognostic (2.94e-2)" "unprognostic (1.22e-1)" "unprognostic (4.48e-2)" "unprognostic (3.46e-1)" "unprognostic (1.35e-2)" "unprognostic (7.41e-3)" IMP3 "BRMS2, C15orf12, FLJ10968, MRPS4" ENSG00000177971 "IMP U3 small nucleolar ribonucleoprotein 3" Q9NV31 15 75639085-75648706 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 353.4;Esophageal basal cells: 228.9;Esophageal suprabasal cells: 259.5" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 353.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 6593296.1;T-cells: 4416906.6" "Tissue enhanced" "Detected in many" "Stomach: 191797.6" "HPA061177, HPA077989" Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 58: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 67 Nucleoli "Nucleoplasm, Cytosol" "HPA061177: , HPA077989: " "unprognostic (1.62e-1)" "unprognostic (1.63e-1)" "unprognostic (1.63e-2)" "unprognostic (2.04e-1)" "unprognostic (1.59e-1)" "unprognostic (3.73e-1)" "unprognostic (3.79e-1)" "unprognostic (3.74e-2)" "unprognostic (1.73e-1)" "unprognostic (3.67e-2)" "potential prognostic favorable (1.04e-5)" "unprognostic (1.79e-3)" "unprognostic (1.73e-1)" "unprognostic (7.96e-2)" "unprognostic (1.55e-3)" "unprognostic (7.20e-2)" "unprognostic (1.54e-1)" "unprognostic (6.61e-2)" "unprognostic (9.80e-3)" "unprognostic (1.60e-1)" "unprognostic (1.30e-2)" "unprognostic (3.48e-1)" "unprognostic (1.92e-1)" "unprognostic (2.95e-1)" "unprognostic (2.81e-2)" "unprognostic (1.53e-1)" "unprognostic (7.81e-2)" "unprognostic (2.09e-2)" "unprognostic (2.83e-1)" "unprognostic (3.91e-1)" "unprognostic (1.26e-2)" IMPA2 ENSG00000141401 "Inositol monophosphatase 2" O14732 18 11981025-12030877 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 338.5;skeletal muscle: 260.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 379.7;Esophageal basal cells: 477.5;Esophageal suprabasal cells: 407.8;Extravillous trophoblasts: 378.0;Pancreatic acinar cells: 884.7;Suprabasal keratinocytes: 243.9" "Cell type enhanced" "Detected in all" "Acinar cells: 884.7;Basal cells: 477.5;Suprabasal cells: 407.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 26.0;neutrophil: 31.5" "Group enriched" "Detected in many" 11 "dendritic cells: 9.0;granulocytes: 31.5;monocytes: 11.4" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 191384053.3;Pancreatic islets: 208680253.7" "Tissue enriched" "Detected in all" "pancreas: 80563504.9" HPA029561 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 85: Squamous epithelial cells - Keratinization" 6 Nucleoplasm Mitochondria "HPA029561: " "unprognostic (1.90e-1)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.17e-2)" "unprognostic (9.91e-2)" "unprognostic (8.36e-3)" "unprognostic (6.55e-3)" "unprognostic (4.64e-2)" "unprognostic (1.17e-1)" "validated prognostic favorable (1.64e-13)" "validated prognostic favorable (9.85e-5)" "potential prognostic favorable (2.96e-5)" "unprognostic (1.07e-3)" "potential prognostic unfavorable (1.78e-5)" "unprognostic (3.25e-1)" "unprognostic (1.62e-2)" "unprognostic (2.12e-1)" "unprognostic (1.04e-1)" "unprognostic (6.66e-2)" "unprognostic (1.67e-1)" "unprognostic (9.60e-3)" "unprognostic (1.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (4.67e-2)" "unprognostic (1.40e-1)" "unprognostic (2.58e-1)" "unprognostic (5.47e-2)" "unprognostic (2.34e-3)" "unprognostic (3.52e-1)" IMPDH1 "LCA11, RP10, sWSS2608" ENSG00000106348 "Inosine monophosphate dehydrogenase 1" P20839 7 128392277-128410252 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "Disease variant, FDA approved drug targets, Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 98.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 89.0;monocytes: 64.6;Neutrophils: 146.0;Retinal bipolar cells: 113.1;Retinal horizontal cells: 74.1;Rod photoreceptor cells: 117.9" "Cell type enhanced" "Detected in many" "Neuronal cells: 117.9;Neutrophils: 146.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 89.2;eosinophil: 89.3;intermediate monocyte: 104.6;myeloid DC: 60.0;neutrophil: 198.3;non-classical monocyte: 136.7" "Group enriched" "Detected in all" 5 "dendritic cells: 60.0;granulocytes: 198.3;monocytes: 136.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Pituitary gland - Gonadotropes, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 22832126.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8539676.6" HPA001400 Approved Supported "Cytosol,Rods & Rings" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 "Cytosol, Rods & Rings" "HPA001400: " "unprognostic (1.05e-3)" "unprognostic (1.83e-2)" "unprognostic (3.79e-1)" "unprognostic (2.27e-3)" "unprognostic (1.00e-2)" "unprognostic (1.10e-1)" "unprognostic (1.14e-3)" "unprognostic (2.16e-2)" "unprognostic (1.87e-1)" "unprognostic (3.04e-2)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (1.09e-4)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (2.75e-8)" "unprognostic (3.46e-2)" "unprognostic (1.55e-1)" "unprognostic (1.30e-3)" "unprognostic (5.22e-2)" "unprognostic (9.50e-2)" "unprognostic (3.77e-2)" "unprognostic (1.10e-2)" "unprognostic (6.14e-2)" "unprognostic (4.74e-2)" "unprognostic (3.20e-2)" "unprognostic (2.89e-1)" "unprognostic (4.40e-1)" "unprognostic (8.84e-2)" "unprognostic (3.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.37e-2)" "unprognostic (1.76e-1)" IMPDH2 ENSG00000178035 "Inosine monophosphate dehydrogenase 2" P12268 3 49024325-49029447 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "GMP biosynthesis, Purine biosynthesis" "DNA-binding, Oxidoreductase, RNA-binding" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 36.5;Enteric stem cells: 139.6;Enteric transient amplifying cells: 105.8;Epididymal basal cells: 46.4;Epididymal efferent duct absorptive cells: 52.6;Gastric chief cells: 44.8;Paneth cells: 139.2" "Cell type enhanced" "Detected in many" "Proliferating cells: 105.8;Secretory gland support: 139.2;Stem cells: 139.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 116672408.8" "Low tissue specificity" "Detected in all" "HPA001400, CAB020717" Approved Supported "Cytosol,Rods & Rings" NA NA 290000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 40 Cytosol "Rods & Rings" "CAB020717: , HPA001400: " "unprognostic (1.39e-2)" "unprognostic (1.76e-1)" "unprognostic (8.39e-2)" "unprognostic (1.67e-2)" "unprognostic (4.55e-3)" "unprognostic (3.85e-1)" "unprognostic (1.73e-3)" "unprognostic (2.04e-3)" "unprognostic (1.03e-2)" "potential prognostic unfavorable (1.23e-4)" "potential prognostic favorable (4.86e-5)" "unprognostic (1.44e-2)" "unprognostic (4.19e-1)" "validated prognostic unfavorable (7.42e-5)" "validated prognostic unfavorable (4.15e-4)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (1.33e-1)" "unprognostic (6.53e-2)" "unprognostic (3.40e-2)" "unprognostic (8.28e-3)" "unprognostic (4.72e-3)" "unprognostic (5.49e-3)" "unprognostic (1.34e-2)" "unprognostic (3.14e-3)" "unprognostic (8.54e-2)" "unprognostic (1.54e-1)" "unprognostic (1.75e-1)" "unprognostic (1.92e-1)" "unprognostic (5.28e-2)" "unprognostic (3.46e-2)" INCA1 ENSG00000196388 "Inhibitor of CDK, cyclin A1 interacting protein 1" Q0VD86 17 4988130-4997610 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 46.1" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 254.0;Early spermatids: 121.7;Late primary spermatocytes: 87.5;Late spermatids: 512.8;Undifferentiated spermatogonia: 38.5" "Cell type enriched" "Detected in many" 45 "Spermatogenic cell types: 512.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2953 "Capillaries: 295301.6" "Not detected" "Not detected" "HPA044359, HPA052401" Uncertain Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 224 "Nucleoplasm, Nuclear bodies" "HPA044359: , HPA052401: " "unprognostic (1.22e-2)" "unprognostic (6.81e-2)" "unprognostic (8.49e-2)" "unprognostic (3.48e-3)" "unprognostic (4.83e-3)" "unprognostic (1.91e-1)" "unprognostic (2.90e-3)" "unprognostic (8.96e-2)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (1.05e-2)" "unprognostic (2.06e-1)" "unprognostic (1.09e-2)" "unprognostic (2.09e-2)" "unprognostic (2.66e-2)" "unprognostic (1.48e-2)" "unprognostic (2.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.53e-1)" "unprognostic (3.07e-1)" "unprognostic (1.34e-2)" "potential prognostic favorable (7.60e-4)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (4.23e-2)" "unprognostic (2.04e-1)" "unprognostic (5.64e-2)" "unprognostic (1.95e-1)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" INCENP FLJ31633 ENSG00000149503 "Inner centromere protein" Q9NQS7 11 62123998-62153169 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 19.8" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 41.0;Esophageal apical cells: 40.8;Megakaryocyte progenitors: 38.8;Monocyte progenitors: 79.6;Neutrophil progenitors: 30.8" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 79.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 1.2;NK-cell: 1.1" "Group enriched" "Detected in many" 7 "granulocytes: 1.2;NK-cells: 1.1" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5478 "Granulosa cells: 547780.5" "Tissue enriched" "Detected in single" 686 "bone marrow: 68607.9" "CAB013292, HPA051339, HPA070550" Enhanced Supported "Nucleoplasm,Nuclear bodies,Kinetochore,Midbody" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 32 "Nuclear bodies, Kinetochore" "Nucleoplasm, Midbody" "CAB013292: , HPA051339: , HPA070550: " "unprognostic (1.70e-1)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (4.90e-3)" "unprognostic (7.12e-2)" "unprognostic (2.06e-1)" "unprognostic (3.20e-1)" "unprognostic (5.84e-2)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (6.69e-5)" "unprognostic (1.28e-3)" "unprognostic (1.96e-1)" "unprognostic (3.31e-2)" "validated prognostic unfavorable (1.49e-4)" "validated prognostic unfavorable (2.27e-4)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.56e-1)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (7.34e-2)" "potential prognostic unfavorable (1.67e-5)" "unprognostic (2.34e-2)" "unprognostic (8.67e-2)" "unprognostic (1.22e-2)" "unprognostic (1.40e-1)" "unprognostic (9.51e-2)" "unprognostic (1.38e-2)" "unprognostic (1.72e-1)" "unprognostic (7.55e-2)" "unprognostic (1.22e-1)" ING4 "my036, p29ING4" ENSG00000111653 "Inhibitor of growth family member 4" Q9UNL4 12 6650301-6663142 "Predicted intracellular proteins" "Apoptosis, Cell cycle" "Chromatin regulator" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 126.8" "Cell type enhanced" "Detected in all" "Platelets: 126.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 335967.1;Neurons: 284111.8" "Tissue enriched" "Detected in some" "bone marrow: 1470250.8" "HPA031817, HPA057338" Approved Supported Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 36 Nucleoplasm "HPA031817: , HPA057338: " "unprognostic (1.11e-1)" "unprognostic (8.72e-2)" "unprognostic (2.42e-1)" "unprognostic (3.24e-2)" "unprognostic (2.90e-2)" "unprognostic (2.59e-1)" "unprognostic (1.77e-1)" "unprognostic (1.83e-2)" "unprognostic (1.69e-2)" "unprognostic (1.11e-1)" "unprognostic (4.59e-3)" "unprognostic (2.14e-2)" "potential prognostic favorable (3.36e-4)" "unprognostic (3.09e-3)" "unprognostic (7.10e-2)" "unprognostic (3.64e-2)" "unprognostic (1.74e-1)" "unprognostic (3.95e-2)" "unprognostic (2.14e-1)" "unprognostic (9.14e-2)" "unprognostic (6.80e-2)" "unprognostic (2.07e-1)" "unprognostic (7.14e-3)" "unprognostic (7.62e-2)" "unprognostic (1.63e-3)" "unprognostic (2.30e-1)" "unprognostic (6.96e-3)" "unprognostic (1.26e-1)" "unprognostic (1.22e-1)" "unprognostic (5.07e-1)" "unprognostic (9.40e-2)" INHA ENSG00000123999 "Inhibin subunit alpha" P05111 2 219569162-219575711 "Predicted secreted proteins" "Growth factor, Hormone" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "adrenal gland: 75.8;ovary: 108.7;testis: 101.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 48.3;Cardiomyocytes: 105.5;Extravillous trophoblasts: 60.8;Granulosa cells: 248.2;Migrating cytotrophoblasts: 39.3;Ovarian stromal cells: 67.9;Sertoli cells: 61.6;Syncytiotrophoblasts: 444.4" "Cell type enhanced" "Detected in many" "Myocytes: 105.5;Reproductive supporting cells: 248.2;Trophoblast cells: 444.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 12.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Granulosa cells: 8165616.4" "Tissue enriched" "Detected in single" 1828 "ovary: 182803.3" "CAB000047, HPA019141, HPA048834" Enhanced Approved "Golgi apparatus,Vesicles" "Secreted to blood" Hormone NA NA 26000 "Cluster 75: Ovary - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 1 Vesicles "Golgi apparatus" "CAB000047: , HPA019141: , HPA048834: " "unprognostic (8.30e-3)" "unprognostic (1.17e-3)" "unprognostic (2.88e-1)" "unprognostic (1.52e-1)" "unprognostic (1.19e-3)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (1.50e-4)" "unprognostic (1.15e-1)" "unprognostic (1.13e-2)" "unprognostic (2.89e-1)" "unprognostic (4.94e-2)" "unprognostic (2.62e-3)" "unprognostic (9.15e-2)" "unprognostic (3.21e-1)" "unprognostic (7.90e-2)" "unprognostic (1.37e-1)" "unprognostic (2.81e-1)" "unprognostic (1.68e-1)" "unprognostic (6.94e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-1)" INO80B "hIes2, HMGA1L4, HMGIYL4, IES2, PAP-1BP, PAPA-1, ZNHIT4" ENSG00000115274 "INO80 complex subunit B" Q9C086 2 74455087-74457944 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 4.2;Bergmann glia: 5.2;Brain excitatory neurons: 5.3;Brain inhibitory neurons: 4.6;Ependymal cells: 6.5;Megakaryocytes: 6.2;Microglia: 4.2;Oligodendrocyte progenitor cells: 3.6;Oligodendrocytes: 5.1;Other brain neurons: 7.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 6.5;Glial cells: 5.2;Megakaryocytes: 6.2;Neuronal cells: 7.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 1948798.2;T-cells: 2681618.2" "Tissue enriched" "Detected in single" 5954 "lymphoid tissue: 595381.0" "HPA070644, HPA078274" Supported "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 98: Neurons - Neurotransmission & signaling" 83 Nucleoplasm "Nucleoli, Nuclear bodies" "HPA070644: , HPA078274: " "unprognostic (3.83e-1)" "unprognostic (3.41e-3)" "unprognostic (4.95e-2)" "unprognostic (8.61e-3)" "unprognostic (2.08e-1)" "unprognostic (2.44e-1)" "unprognostic (1.95e-1)" "potential prognostic favorable (5.19e-4)" "unprognostic (1.03e-2)" "unprognostic (2.37e-1)" "unprognostic (7.62e-3)" "unprognostic (3.25e-1)" "unprognostic (2.97e-1)" "unprognostic (5.43e-3)" "unprognostic (9.00e-2)" "unprognostic (2.90e-2)" "unprognostic (8.00e-2)" "unprognostic (8.26e-3)" "unprognostic (9.40e-2)" "unprognostic (1.58e-1)" "unprognostic (5.29e-2)" "unprognostic (2.22e-1)" "unprognostic (6.14e-2)" "unprognostic (4.96e-2)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (3.92e-2)" "unprognostic (1.97e-2)" "unprognostic (1.83e-1)" "unprognostic (2.67e-1)" "unprognostic (5.32e-2)" INO80E "CCDC95, FLJ90652" ENSG00000169592 "INO80 complex subunit E" Q8NBZ0 16 29995715-30005793 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 295 "T-cells: 29504.6" "Group enriched" "Detected in some" "lymphoid tissue: 301588.1;ovary: 253108.3" HPA043146 Approved Supported "Nucleoplasm,Nucleoli rim" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 63 Nucleoplasm "Nucleoli rim" "HPA043146: " "unprognostic (1.54e-1)" "unprognostic (8.05e-2)" "unprognostic (8.79e-2)" "unprognostic (7.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.53e-1)" "unprognostic (1.22e-1)" "unprognostic (9.34e-3)" "unprognostic (3.27e-1)" "unprognostic (1.99e-1)" "unprognostic (2.53e-2)" "unprognostic (2.46e-1)" "unprognostic (2.93e-1)" "unprognostic (4.09e-3)" "unprognostic (1.04e-1)" "unprognostic (4.98e-2)" "unprognostic (3.06e-2)" "unprognostic (2.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.50e-2)" "unprognostic (2.42e-2)" "unprognostic (1.60e-2)" "unprognostic (9.03e-3)" "unprognostic (1.30e-1)" "unprognostic (1.91e-1)" "unprognostic (3.60e-1)" "unprognostic (4.60e-1)" "unprognostic (1.35e-1)" "unprognostic (3.83e-1)" "unprognostic (5.23e-2)" "unprognostic (3.80e-2)" INPP5B ENSG00000204084 "Inositol polyphosphate-5-phosphatase B" P32019 1 37860697-37947057 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 145.7;Retinal ganglion cells: 166.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1383610.1;T-cells: 1271852.7" "Low tissue specificity" "Detected in many" HPA028803 Approved Supported "Primary cilium tip,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 2 Cytosol "Primary cilium tip" "HPA028803: " "unprognostic (2.92e-2)" "unprognostic (8.74e-2)" "unprognostic (1.02e-1)" "unprognostic (1.56e-1)" "unprognostic (1.25e-1)" "unprognostic (8.00e-2)" "unprognostic (7.45e-3)" "unprognostic (7.71e-2)" "potential prognostic favorable (3.03e-4)" "unprognostic (2.85e-2)" "unprognostic (1.76e-1)" "unprognostic (2.91e-2)" "unprognostic (4.62e-1)" "unprognostic (6.60e-3)" "unprognostic (1.27e-2)" "potential prognostic favorable (8.55e-5)" "unprognostic (1.58e-1)" "unprognostic (5.29e-2)" "unprognostic (3.27e-2)" "unprognostic (4.88e-2)" "unprognostic (2.01e-1)" "potential prognostic favorable (4.53e-4)" "unprognostic (3.92e-2)" "unprognostic (4.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.51e-2)" "unprognostic (6.23e-2)" "unprognostic (1.91e-2)" "unprognostic (1.49e-1)" "unprognostic (1.13e-1)" "unprognostic (1.39e-1)" INPP5D "hp51CN, SHIP, SHIP1" ENSG00000168918 "Inositol polyphosphate-5-phosphatase D" Q92835 2 233059967-233207903 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 47.7;lymphoid tissue: 95.6" "Cell type enriched" "Detected in many" 10 "Microglia: 1021.1" "Cell type enriched" "Detected in many" 10 "Glial cells: 1021.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 1257.2;endothelial cell: 300.2;leukocyte: 431.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 43.8;lymphoma: 38.7" "Adipose subcutaneous - T-cells, Breast - T-cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 76268454.5;Macrophages: 48137657.1;T-cells: 54629672.5" "Tissue enhanced" "Detected in many" "lymphoid tissue: 77358055.9" "CAB016300, HPA070455" Enhanced Supported Cytosol No No 830000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 24 Cytosol "CAB016300: , HPA070455: " "unprognostic (6.03e-3)" "unprognostic (1.13e-1)" "unprognostic (1.51e-2)" "unprognostic (1.78e-1)" "unprognostic (2.59e-1)" "unprognostic (1.29e-1)" "unprognostic (2.62e-1)" "unprognostic (9.69e-2)" "potential prognostic favorable (7.21e-5)" "unprognostic (4.70e-2)" "unprognostic (7.17e-2)" "unprognostic (3.52e-2)" "unprognostic (2.70e-2)" "unprognostic (1.25e-1)" "unprognostic (1.84e-2)" "unprognostic (5.20e-2)" "unprognostic (3.41e-2)" "unprognostic (6.36e-2)" "unprognostic (3.24e-1)" "unprognostic (1.72e-1)" "unprognostic (2.77e-1)" "unprognostic (2.18e-1)" "unprognostic (8.93e-3)" "unprognostic (8.03e-2)" "unprognostic (1.01e-1)" "unprognostic (6.53e-2)" "unprognostic (2.21e-1)" "unprognostic (1.99e-1)" "unprognostic (4.65e-2)" "unprognostic (1.55e-2)" "unprognostic (1.40e-1)" INPP5F "hSac2, KIAA0966, SAC2" ENSG00000198825 "Inositol polyphosphate-5-phosphatase F" Q9Y2H2 10 119726042-119829147 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 137.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 516.9;Other brain neurons: 170.0" "Cell type enhanced" "Detected in all" "Glial cells: 516.9" "Cell type enhanced" "Detected in all" "Bergmann glia: 569.3" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 71.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 5 "skin cancer: 74.7;testis cancer: 167.2" "Prostate - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "cerebral cortex: 460360.6;lymphoid tissue: 453281.4" HPA042605 Supported Vesicles NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" 11 Vesicles "HPA042605: " "unprognostic (4.43e-2)" "unprognostic (6.84e-3)" "unprognostic (9.93e-2)" "unprognostic (1.22e-1)" "unprognostic (5.82e-2)" "unprognostic (1.52e-1)" "unprognostic (2.52e-2)" "potential prognostic favorable (1.63e-5)" "unprognostic (8.80e-2)" "unprognostic (2.75e-1)" "unprognostic (1.42e-3)" "potential prognostic favorable (1.06e-4)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (3.99e-5)" "unprognostic (2.52e-1)" "unprognostic (4.81e-1)" "unprognostic (1.98e-2)" "unprognostic (2.08e-2)" "unprognostic (3.03e-2)" "unprognostic (3.33e-2)" "potential prognostic unfavorable (9.12e-6)" "unprognostic (7.11e-2)" "unprognostic (2.10e-2)" "unprognostic (7.41e-2)" "unprognostic (2.99e-2)" "unprognostic (6.48e-2)" "unprognostic (1.34e-1)" "unprognostic (1.19e-1)" "unprognostic (1.25e-1)" "unprognostic (6.32e-2)" "unprognostic (3.40e-2)" INPPL1 SHIP2 ENSG00000165458 "Inositol polyphosphate phosphatase like 1" O15357 11 72223701-72239147 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Immunity, Lipid metabolism" "Actin-binding, Hydrolase" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "astrocyte: 76.3;central nervous system macrophage: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 7078677.4" HPA037601 Approved Supported "Golgi apparatus,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 71 Cytosol "Golgi apparatus" "HPA037601: " "unprognostic (2.13e-2)" "unprognostic (3.31e-1)" "unprognostic (3.34e-3)" "unprognostic (1.05e-2)" "unprognostic (8.53e-2)" "unprognostic (4.39e-2)" "unprognostic (7.21e-3)" "unprognostic (1.39e-1)" "unprognostic (3.62e-1)" "unprognostic (5.19e-2)" "unprognostic (1.94e-2)" "unprognostic (6.16e-2)" "unprognostic (5.77e-3)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (2.55e-1)" "unprognostic (6.71e-2)" "unprognostic (2.96e-2)" "unprognostic (1.48e-2)" "unprognostic (9.30e-2)" "unprognostic (7.15e-3)" "unprognostic (5.40e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (9.60e-4)" "potential prognostic unfavorable (9.11e-4)" "unprognostic (2.82e-2)" "unprognostic (1.22e-2)" "unprognostic (2.58e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-1)" "unprognostic (1.67e-3)" "unprognostic (5.92e-2)" INSM2 "IA-6, Mlt1" ENSG00000168348 "INSM transcriptional repressor 2" Q96T92 14 35534164-35537054 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;retina: 2.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 1.0;Brain inhibitory neurons: 1.5;Breast myoepithelial cells: 2.6;Cone photoreceptor cells: 4.1;Early primary spermatocytes: 5.1;Gastric chief cells: 1.1;Other brain neurons: 3.0;Retinal ganglion cells: 3.9;Retinal horizontal cells: 2.0;Rod photoreceptor cells: 4.2" "Cell type enhanced" "Detected in some" "Neuronal cells: 4.2;Secretory gland support: 2.6;Spermatogenic cell types: 5.1" "Cell type enhanced" "Detected in some" "mammillary body: 10.7;midbrain-derived inhibitory: 5.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 18 "Neuroblastoma: 49.9" "Adrenal gland - Adrenal medulla cells" "Region enhanced" "Detected in single" "hypothalamus: 1.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 165 "lymphoid tissue: 16526.9" "HPA044885, HPA051925" Uncertain Approved Nucleoplasm NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 82: Dendritic cells - Antigen presentation" Nucleoplasm "HPA044885: , HPA051925: " "potential prognostic favorable (7.51e-4)" INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic acinar cells: 1376.5;Peritubular myoid cells: 827.8" "Cell type enhanced" "Detected in all" "Acinar cells: 1376.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.6" "Cancer enhanced" "Detected in all" "Myeloma: 24.6" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Alveolar cell types: 84133269.2" "Low tissue specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane,Primary cilium transition zone,Centriolar satellite,Basal body" NA Yes 130000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 104 "Vesicles, Plasma membrane" "Primary cilium transition zone, Centriolar satellite, Basal body" "HPA036302: , HPA036303: " "unprognostic (1.21e-2)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" "unprognostic (4.41e-1)" "unprognostic (2.63e-1)" "unprognostic (2.03e-2)" "unprognostic (2.46e-1)" "unprognostic (4.55e-1)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "validated prognostic favorable (5.63e-8)" "validated prognostic favorable (5.67e-5)" "unprognostic (2.44e-1)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (2.10e-1)" "unprognostic (3.91e-2)" "unprognostic (9.70e-2)" "potential prognostic favorable (2.02e-4)" "unprognostic (2.30e-1)" "unprognostic (3.88e-2)" "unprognostic (6.86e-2)" "unprognostic (2.16e-2)" "unprognostic (1.41e-1)" "unprognostic (4.40e-1)" "unprognostic (2.01e-1)" "unprognostic (2.55e-2)" "unprognostic (1.14e-2)" "unprognostic (2.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.29e-1)" INSYN1 "C15orf59, LOC388135, MGC131524" ENSG00000205363 "Inhibitory synaptic factor 1" Q2T9L4 15 73735458-73753351 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.0;heart muscle: 41.8" "Cell type enhanced" "Detected in some" "Astrocytes: 18.1;Bergmann glia: 32.2;Brain excitatory neurons: 8.2;Brain inhibitory neurons: 14.1;Epididymal clear cells: 8.2;Epididymal efferent duct absorptive cells: 9.5;Müller glia: 7.7;Oligodendrocyte progenitor cells: 7.3;Other brain neurons: 10.3;Podocytes: 19.4;Renal collecting duct intercalated cells: 12.0;Retinal amacrine cells: 11.8;Retinal bipolar cells: 8.2" "Cell type enhanced" "Detected in many" "Ductal cells: 12.0;Glial cells: 32.2;Neuronal cells: 14.1;Renal nephron cells: 19.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 8 "Kidney Chromophobe (TCGA): 156.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Intercalated cells, Pancreas - Beta cells, Pituitary gland - Thyrotropes, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 36 "cerebral cortex: 3613.8" HPA041563 Approved Approved Nucleoplasm,Cytosol No NA "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 18 "Nucleoplasm, Cytosol" "HPA041563: " "unprognostic (2.75e-1)" "unprognostic (8.98e-2)" "unprognostic (1.09e-1)" "unprognostic (2.77e-1)" "unprognostic (9.48e-3)" "unprognostic (2.06e-1)" "unprognostic (8.46e-2)" "unprognostic (7.59e-3)" "potential prognostic favorable (5.45e-6)" "unprognostic (2.27e-3)" "unprognostic (2.52e-1)" "unprognostic (7.44e-2)" "unprognostic (1.30e-1)" "unprognostic (1.35e-1)" "potential prognostic favorable (1.47e-4)" "unprognostic (3.25e-2)" "unprognostic (3.02e-2)" "unprognostic (2.39e-1)" "unprognostic (4.34e-2)" "unprognostic (3.21e-2)" "unprognostic (1.49e-1)" INTS14 "C15orf44, DKFZP564O1664, VWA9" ENSG00000138614 "Integrator complex subunit 14" Q96SY0 15 65578753-65611289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 828593.7" "Tissue enhanced" "Detected in many" "cerebral cortex: 558086.9;lymphoid tissue: 598086.4" "HPA040255, HPA040651" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Mitochondria" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 40 "Nucleoplasm, Nuclear bodies, Mitochondria" "Nuclear membrane" "HPA040255: , HPA040651: " "unprognostic (2.45e-2)" "unprognostic (4.38e-2)" "unprognostic (3.85e-2)" "unprognostic (3.31e-1)" "unprognostic (2.19e-1)" "unprognostic (1.93e-1)" "unprognostic (7.11e-2)" "unprognostic (1.71e-2)" "unprognostic (1.06e-2)" "validated prognostic favorable (1.29e-7)" "validated prognostic favorable (1.75e-4)" "unprognostic (1.14e-1)" "unprognostic (6.27e-2)" "unprognostic (1.01e-1)" "unprognostic (1.08e-2)" "unprognostic (5.79e-2)" "unprognostic (1.65e-1)" "unprognostic (2.03e-1)" "unprognostic (3.86e-1)" "unprognostic (4.16e-2)" "unprognostic (2.03e-2)" "unprognostic (7.65e-2)" "unprognostic (2.30e-2)" "unprognostic (7.95e-2)" "unprognostic (5.23e-2)" "unprognostic (6.40e-2)" "unprognostic (5.35e-2)" "unprognostic (2.19e-1)" "unprognostic (4.66e-3)" INTS7 "C1orf73, DKFZP434B168, INT7" ENSG00000143493 "Integrator complex subunit 7" Q9NVH2 1 211940399-212035557 "Essential proteins, Predicted intracellular proteins" "DNA damage" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte-Erythroid progenitors: 108.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 1681 "bone marrow: 210092.1;fallopian tube: 207971.5;lymphoid tissue: 173544.7;pancreas: 80690.1" HPA072611 Supported "Nuclear bodies" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 "Nuclear bodies" "HPA072611: " "unprognostic (1.01e-1)" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.39e-2)" "unprognostic (1.02e-2)" "unprognostic (3.29e-2)" "unprognostic (7.20e-2)" "unprognostic (3.57e-3)" "unprognostic (1.25e-1)" "unprognostic (2.09e-3)" "unprognostic (8.06e-2)" "unprognostic (7.39e-2)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (7.98e-3)" "unprognostic (4.95e-2)" "potential prognostic unfavorable (1.84e-6)" "unprognostic (1.50e-2)" "unprognostic (1.20e-1)" "unprognostic (3.43e-1)" "unprognostic (4.68e-3)" "unprognostic (2.72e-2)" "unprognostic (1.12e-1)" "unprognostic (2.96e-2)" "unprognostic (1.64e-1)" "unprognostic (1.31e-1)" "unprognostic (1.64e-1)" "unprognostic (2.14e-3)" "unprognostic (1.37e-1)" "unprognostic (4.82e-2)" "unprognostic (3.60e-1)" "unprognostic (2.05e-1)" INTS8 "C8orf52, FLJ20530, INT8, MGC131633" ENSG00000164941 "Integrator complex subunit 8" Q75QN2 8 94813311-94881746 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 164.3" "Cell type enhanced" "Detected in many" "Neuronal cells: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in some" "intestine: 2350232.7" HPA057299 Approved Approved Nucleoplasm Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 19 Nucleoplasm "HPA057299: " "unprognostic (1.38e-1)" "unprognostic (1.50e-2)" "unprognostic (2.56e-2)" "unprognostic (2.79e-2)" "unprognostic (2.17e-1)" "unprognostic (4.71e-2)" "unprognostic (2.33e-1)" "unprognostic (1.35e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (1.27e-5)" "unprognostic (1.14e-1)" "unprognostic (6.40e-2)" "potential prognostic unfavorable (2.06e-4)" "potential prognostic unfavorable (1.86e-6)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (9.29e-2)" "unprognostic (2.28e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (1.40e-5)" "unprognostic (5.60e-2)" "unprognostic (2.94e-2)" "unprognostic (2.46e-3)" "unprognostic (2.03e-1)" "unprognostic (6.00e-2)" "unprognostic (6.73e-2)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" "unprognostic (1.77e-1)" "unprognostic (7.57e-2)" "unprognostic (3.75e-2)" INTS9 "CPSF2L, FLJ10871, RC-74" ENSG00000104299 "Integrator complex subunit 9" Q9NV88 8 28767661-28890242 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 184.0;Rod photoreceptor cells: 136.8" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 184.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 4847269.0" "Tissue enriched" "Detected in many" "intestine: 1706029.6" "HPA051615, HPA066822" Enhanced Nucleoplasm Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 38 Nucleoplasm "HPA051615: , HPA066822: " "unprognostic (1.57e-2)" "unprognostic (2.42e-2)" "unprognostic (2.13e-1)" "unprognostic (2.27e-1)" "unprognostic (2.18e-2)" "unprognostic (1.53e-2)" "unprognostic (2.30e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (2.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.86e-3)" "unprognostic (4.03e-2)" "unprognostic (5.75e-2)" "unprognostic (1.19e-2)" "unprognostic (6.94e-2)" "unprognostic (9.03e-2)" "unprognostic (1.91e-1)" "unprognostic (9.56e-3)" "unprognostic (1.68e-1)" "unprognostic (5.95e-2)" "unprognostic (9.61e-2)" "unprognostic (2.21e-2)" "unprognostic (1.01e-1)" "unprognostic (1.85e-2)" "unprognostic (1.89e-2)" "unprognostic (1.86e-2)" "unprognostic (1.82e-2)" "unprognostic (9.46e-2)" "unprognostic (3.54e-1)" "unprognostic (7.93e-2)" "unprognostic (4.34e-2)" INVS NPHP2 ENSG00000119509 Inversin Q9Y283 9 100099243-100302175 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Calmodulin-binding, Developmental protein" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 980 "Granulosa cells: 90687.7;Proximal tubules: 105301.0" "Not detected" "Not detected" HPA049994 Approved "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 4 "Primary cilium, Cytosol" "Centrosome, Basal body" "HPA049994: " "unprognostic (1.80e-1)" "unprognostic (2.10e-2)" "unprognostic (4.75e-2)" "unprognostic (1.52e-2)" "unprognostic (1.30e-1)" "unprognostic (5.35e-2)" "unprognostic (1.64e-1)" "unprognostic (3.26e-3)" "unprognostic (5.45e-2)" "unprognostic (5.62e-2)" "validated prognostic favorable (4.48e-7)" "validated prognostic favorable (6.46e-5)" "unprognostic (3.89e-1)" "unprognostic (1.38e-2)" "unprognostic (5.20e-2)" "unprognostic (1.11e-2)" "unprognostic (1.35e-1)" "unprognostic (9.07e-2)" "unprognostic (2.97e-2)" "unprognostic (7.08e-2)" "unprognostic (3.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.29e-2)" "unprognostic (1.09e-1)" "potential prognostic favorable (9.99e-4)" "unprognostic (2.45e-2)" "unprognostic (3.49e-1)" "unprognostic (4.82e-1)" "unprognostic (2.57e-1)" "unprognostic (2.12e-2)" "unprognostic (9.47e-2)" IP6K3 "IHPK3, INSP6K3" ENSG00000161896 "Inositol hexakisphosphate kinase 3" Q96PC2 6 33721662-33746905 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 290.7;tongue: 77.8" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 70.2;Myonuclei: 112.6;Myosatellite cells: 57.6;Podocytes: 48.5;Proximal tubule cells: 42.6;Thymic myoid cells: 80.2" "Group enriched" "Detected in many" 4 "Myocytes: 112.6;Renal nephron cells: 48.5;Stem cells: 57.6;Stromal cells: 80.2" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 7.7;oligodendrocyte: 26.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.8;testis cancer: 4.9" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053644, HPA062531" Enhanced Approved Nucleoplasm,Cytosol Yes NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 13 Nucleoplasm Cytosol "HPA053644: , HPA062531: " "unprognostic (2.92e-1)" "potential prognostic favorable (1.91e-5)" "unprognostic (4.56e-2)" "unprognostic (1.49e-1)" "unprognostic (1.82e-1)" "unprognostic (2.93e-3)" "unprognostic (4.57e-2)" "unprognostic (3.42e-3)" "unprognostic (4.23e-1)" "unprognostic (1.11e-3)" "unprognostic (7.16e-2)" "unprognostic (2.95e-2)" "unprognostic (1.32e-1)" "unprognostic (2.56e-1)" "unprognostic (1.12e-1)" "unprognostic (4.20e-3)" "unprognostic (7.20e-2)" "unprognostic (6.51e-3)" "unprognostic (4.07e-2)" "unprognostic (1.68e-1)" "unprognostic (2.90e-3)" IPO4 "FLJ23338, Imp4" ENSG00000196497 "Importin 4" Q8TEX9 14 24180219-24188869 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 55.2" "Cell type enhanced" "Detected in some" "Astrocytes: 2.3;Bergmann glia: 2.0;Brain excitatory neurons: 1.5;Brain inhibitory neurons: 1.5;Choroid plexus epithelial cells: 1.8;Distal convoluted tubule cells: 1.1;Ependymal cells: 3.2;Loop of henle epithelial cells: 1.2;Oligodendrocyte progenitor cells: 1.6;Oligodendrocytes: 1.8;Other brain neurons: 1.7;Proximal tubule cells: 1.5;Renal collecting duct principal cells: 1.5" "Cell type enhanced" "Detected in some" "Ciliated cells: 3.2;Ductal cells: 1.5;Glial cells: 2.3;Neuronal cells: 1.7;Renal nephron cells: 1.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 86247085.5" "Low tissue specificity" "Detected in many" "HPA039043, HPA064572" Uncertain Approved Cytosol NA NA 38000 "Cluster 30: Non-specific - DNA binding" "Cluster 21: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 98: Neurons - Neurotransmission & signaling" 47 Cytosol "HPA039043: , HPA064572: " "unprognostic (1.25e-3)" "unprognostic (1.63e-1)" "unprognostic (1.25e-1)" "unprognostic (1.54e-1)" "unprognostic (2.58e-2)" "unprognostic (2.43e-1)" "unprognostic (3.14e-1)" "unprognostic (1.21e-3)" "unprognostic (1.19e-2)" "unprognostic (2.15e-1)" "unprognostic (4.11e-2)" "unprognostic (2.26e-1)" "unprognostic (1.15e-1)" "validated prognostic unfavorable (4.46e-7)" "validated prognostic unfavorable (1.60e-4)" "unprognostic (7.39e-3)" "unprognostic (7.95e-3)" "unprognostic (3.03e-1)" "unprognostic (2.36e-1)" "unprognostic (3.30e-2)" "unprognostic (9.47e-2)" "unprognostic (8.50e-2)" "unprognostic (1.93e-1)" "unprognostic (5.70e-2)" "unprognostic (1.39e-1)" "unprognostic (1.99e-1)" "unprognostic (3.95e-2)" "unprognostic (2.98e-1)" "unprognostic (2.02e-1)" "unprognostic (3.60e-2)" "unprognostic (3.63e-1)" IPO5 "IMB3, KPNB3, MGC2068, PSE1, RANBP5" ENSG00000065150 "Importin 5" O00410 13 97953658-98024296 "Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 196.2" "Cell type enhanced" "Detected in all" "Early spermatids: 1447.9;Late primary spermatocytes: 586.0;Late spermatids: 3125.4" "Cell type enriched" "Detected in all" 18 "Spermatogenic cell types: 3125.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB009110, HPA040983, HPA056548" Approved Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus,Cytosol" NA NA 770000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 114 "Nucleoplasm, Nuclear membrane" "Golgi apparatus, Cytosol" "CAB009110: , HPA040983: , HPA056548: " "unprognostic (1.30e-1)" "unprognostic (1.36e-1)" "unprognostic (7.87e-2)" "unprognostic (4.95e-2)" "unprognostic (1.63e-1)" "unprognostic (2.63e-2)" "unprognostic (4.56e-2)" "unprognostic (2.79e-1)" "unprognostic (7.57e-2)" "unprognostic (4.04e-2)" "potential prognostic favorable (2.45e-9)" "unprognostic (1.86e-3)" "unprognostic (2.39e-1)" "unprognostic (2.11e-2)" "potential prognostic unfavorable (4.06e-6)" "unprognostic (8.19e-2)" "unprognostic (2.14e-3)" "unprognostic (7.91e-3)" "unprognostic (2.55e-1)" "unprognostic (1.90e-1)" "unprognostic (5.36e-2)" "unprognostic (4.94e-2)" "unprognostic (4.46e-2)" "unprognostic (9.71e-2)" "unprognostic (2.16e-3)" "unprognostic (5.63e-2)" "unprognostic (1.14e-1)" "unprognostic (2.75e-1)" "unprognostic (1.34e-1)" "unprognostic (9.91e-2)" "unprognostic (1.39e-1)" IPO8 "IMP8, RANBP8" ENSG00000133704 "Importin 8" O15397 12 30628988-30695869 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 22358279.1" "Low tissue specificity" "Detected in many" "HPA018439, HPA023765" Uncertain Approved "Nucleoplasm,Vesicles,End piece" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 77 Nucleoplasm "Vesicles, End piece" "HPA018439: , HPA023765: " "unprognostic (3.68e-1)" "unprognostic (2.50e-2)" "unprognostic (2.24e-1)" "unprognostic (2.78e-2)" "unprognostic (2.23e-1)" "unprognostic (1.00e-1)" "unprognostic (8.85e-2)" "unprognostic (2.46e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (3.23e-4)" "potential prognostic favorable (1.89e-5)" "unprognostic (1.54e-3)" "unprognostic (4.12e-2)" "unprognostic (1.04e-2)" "unprognostic (2.08e-2)" "unprognostic (2.66e-2)" "unprognostic (1.97e-3)" "unprognostic (1.34e-1)" "unprognostic (1.76e-1)" "unprognostic (3.23e-2)" "unprognostic (5.52e-2)" "unprognostic (9.47e-2)" "unprognostic (1.13e-1)" "unprognostic (7.72e-2)" "unprognostic (6.79e-2)" "unprognostic (8.42e-2)" "unprognostic (1.88e-2)" "unprognostic (3.73e-1)" "unprognostic (4.29e-1)" "unprognostic (1.99e-2)" "unprognostic (1.63e-1)" IPPK "C9orf12, FLJ13163, INSP5K2, IP5K, IPK1" ENSG00000127080 "Inositol-pentakisphosphate 2-kinase" Q9H8X2 9 92613183-92670131 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 30.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 207.9;Esophageal basal cells: 89.6;Esophageal suprabasal cells: 163.0;Suprabasal keratinocytes: 139.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 207.9;Suprabasal cells: 163.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 103 "Neurons: 10333.6" "Not detected" "Not detected" HPA020603 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 85: Squamous epithelial cells - Keratinization" Cytosol "HPA020603: " "unprognostic (2.79e-1)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (9.95e-2)" "unprognostic (3.47e-2)" "unprognostic (1.28e-1)" "unprognostic (5.53e-1)" "potential prognostic favorable (7.67e-5)" "unprognostic (3.19e-1)" "unprognostic (4.74e-1)" "potential prognostic favorable (5.24e-6)" "unprognostic (1.51e-3)" "unprognostic (9.31e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (9.53e-4)" "unprognostic (4.34e-2)" "unprognostic (2.05e-1)" "unprognostic (4.06e-2)" "unprognostic (1.77e-1)" "unprognostic (8.62e-2)" "unprognostic (4.36e-2)" "unprognostic (1.84e-1)" "unprognostic (8.85e-2)" "unprognostic (2.18e-2)" "unprognostic (6.70e-2)" "unprognostic (3.27e-1)" "unprognostic (1.96e-2)" "unprognostic (4.15e-2)" "unprognostic (2.03e-1)" "unprognostic (2.21e-1)" IQCB1 "KIAA0036, NPHP5, SLSN5" ENSG00000173226 "IQ motif containing B1" Q15051 3 121769761-121835079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Calmodulin-binding "Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 274.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 6717898.3" "Group enriched" "Detected in some" 357 "fallopian tube: 35520.8;lymphoid tissue: 35927.3" HPA042028 Approved Approved Uncertain "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 27 "Microtubules, Cytokinetic bridge, Mitotic spindle" "Nucleoplasm, Primary cilium, Basal body" "HPA042028: " "unprognostic (1.35e-2)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (4.78e-3)" "unprognostic (2.76e-1)" "unprognostic (3.92e-1)" "unprognostic (1.15e-1)" "unprognostic (3.22e-1)" "unprognostic (1.58e-2)" "unprognostic (1.09e-1)" "unprognostic (4.20e-3)" "unprognostic (1.74e-1)" "unprognostic (4.27e-2)" "potential prognostic unfavorable (3.74e-5)" "unprognostic (1.53e-2)" "unprognostic (2.22e-3)" "unprognostic (6.62e-2)" "unprognostic (6.29e-2)" "unprognostic (4.78e-2)" "unprognostic (2.98e-1)" "unprognostic (4.73e-1)" "unprognostic (2.63e-1)" "unprognostic (3.88e-2)" "unprognostic (3.91e-3)" "validated prognostic favorable (1.15e-4)" "validated prognostic favorable (2.35e-4)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (5.13e-1)" "unprognostic (5.38e-2)" "unprognostic (7.11e-2)" IQCE KIAA1023 ENSG00000106012 "IQ motif containing E" Q6IPM2 7 2558972-2614733 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 561.7;Late primary spermatocytes: 185.1;Late spermatids: 557.6;Respiratory ciliated cells: 137.7" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 561.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.8" "Group enriched" "Detected in many" 4 "dendritic cells: 2.4;granulocytes: 3.8;monocytes: 1.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 4737329.9" "Tissue enriched" "Detected in single" 6382 "fallopian tube: 638208.7" HPA019515 Approved Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Primary cilium" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 67: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 9 "Nucleoplasm, Plasma membrane" "Nuclear membrane, Primary cilium" "HPA019515: " "unprognostic (1.77e-1)" "unprognostic (4.05e-1)" "unprognostic (4.67e-1)" "unprognostic (8.65e-3)" "unprognostic (1.07e-1)" "unprognostic (3.01e-1)" "unprognostic (7.67e-2)" "unprognostic (5.90e-2)" "unprognostic (1.94e-1)" "unprognostic (6.50e-3)" "unprognostic (1.51e-1)" "unprognostic (2.49e-1)" "unprognostic (5.41e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (5.19e-2)" "unprognostic (1.20e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-1)" "unprognostic (3.69e-1)" "unprognostic (2.16e-2)" "unprognostic (2.16e-1)" "unprognostic (2.63e-2)" "unprognostic (2.35e-2)" "unprognostic (8.56e-2)" "unprognostic (6.75e-2)" "unprognostic (2.55e-1)" "unprognostic (2.02e-2)" "unprognostic (1.47e-2)" "unprognostic (4.56e-2)" "unprognostic (3.20e-2)" "unprognostic (2.43e-1)" IQCH FLJ12476 ENSG00000103599 "IQ motif containing H" Q86VS3 15 67254786-67502260 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 6.4;testis: 10.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 169.0;Early primary spermatocytes: 222.6;Endometrial ciliated cells: 189.5;Ependymal cells: 446.6;Fallopian tube ciliated cells: 191.5;Myonuclei: 169.5;Respiratory ciliated cells: 467.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 467.5;Spermatogenic cell types: 222.6" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 134.5;ependymal cell: 475.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA040845 Uncertain Approved "Vesicles,Cytosol,Mid piece" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" Cytosol "Vesicles, Mid piece" "HPA040845: " "unprognostic (1.60e-1)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (6.54e-3)" "unprognostic (2.09e-1)" "unprognostic (3.16e-2)" "unprognostic (4.40e-1)" "unprognostic (9.98e-3)" "potential prognostic favorable (6.75e-5)" "unprognostic (1.75e-3)" "potential prognostic favorable (4.46e-4)" "unprognostic (3.38e-2)" "unprognostic (9.50e-2)" "unprognostic (7.02e-2)" "unprognostic (1.97e-1)" "unprognostic (2.12e-1)" "unprognostic (5.08e-1)" "unprognostic (1.99e-1)" "unprognostic (3.23e-2)" "unprognostic (1.80e-1)" "unprognostic (1.12e-2)" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-2)" "unprognostic (3.74e-2)" IQCN KIAA1683 ENSG00000130518 "IQ motif containing N" Q9H0B3 19 18257098-18274500 "Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 30.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 113.7;Early spermatids: 122.1;Late spermatids: 141.7;Medullary thymic epithelial cells: 127.2;Transitional alveolar cells: 115.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 19598 "fallopian tube: 1959777.4" HPA042409 Enhanced Approved "Acrosome,Equatorial segment" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 20: Non-specific - Transcription regulation" 10 "Acrosome, Equatorial segment" "HPA042409: " "unprognostic (8.42e-3)" "unprognostic (5.98e-2)" "unprognostic (1.44e-2)" "unprognostic (1.73e-1)" "unprognostic (7.09e-3)" "unprognostic (2.95e-2)" "unprognostic (2.52e-3)" "unprognostic (6.88e-2)" "unprognostic (4.58e-2)" "unprognostic (4.72e-1)" "unprognostic (1.52e-1)" "unprognostic (9.60e-2)" "potential prognostic favorable (5.92e-4)" "unprognostic (9.88e-3)" "unprognostic (2.09e-1)" "unprognostic (1.24e-2)" "unprognostic (1.56e-1)" "unprognostic (3.85e-2)" "unprognostic (8.47e-2)" "unprognostic (2.37e-1)" "unprognostic (1.25e-1)" IQGAP3 ENSG00000183856 "IQ motif containing GTPase activating protein 3" Q86VI3 1 156525405-156572604 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 14.7" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 17.4;Enteric transient amplifying cells: 27.7;Erythrocyte progenitors: 11.3;Foveolar cells: 13.3;Gastric progenitor cells: 39.7;Late spermatids: 40.3;Monocyte progenitors: 39.2;Neutrophil progenitors: 14.7" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 39.2;Proliferating cells: 39.7;Spermatogenic cell types: 40.3" "Cell type enhanced" "Detected in some" "deep-layer near-projecting: 2.7;lower rhombic lip: 1.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Oocytes: 1380302.3" "Group enriched" "Detected in some" 255 "intestine: 29207.1;lymphoid tissue: 21791.1" "HPA030142, HPA030143" Uncertain Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 44: Bone marrow - Nuclear processes" "Cluster 24: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 52 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA030142: , HPA030143: " "unprognostic (3.55e-1)" "unprognostic (9.29e-2)" "unprognostic (4.26e-1)" "unprognostic (4.52e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-1)" "unprognostic (1.71e-1)" "unprognostic (1.48e-1)" "unprognostic (2.79e-2)" "validated prognostic unfavorable (3.88e-8)" "validated prognostic unfavorable (9.32e-7)" "potential prognostic unfavorable (1.74e-6)" "validated prognostic unfavorable (4.53e-5)" "validated prognostic unfavorable (4.57e-4)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.18e-4)" "unprognostic (1.29e-1)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (3.04e-3)" "unprognostic (5.96e-3)" "unprognostic (4.88e-2)" "unprognostic (1.66e-2)" "unprognostic (3.26e-1)" "unprognostic (8.74e-2)" "unprognostic (7.04e-2)" "unprognostic (4.47e-2)" "unprognostic (3.58e-1)" "unprognostic (3.82e-2)" IQSEC2 "BRAG1, IQ-ArfGEF, KIAA0522, MRX1, MRX18, MRX78" ENSG00000124313 "IQ motif and Sec7 domain ArfGEF 2" Q5JU85 X 53225828-53321350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 57.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 83.8;Late spermatids: 111.7;Podocytes: 267.4" "Cell type enhanced" "Detected in many" "Renal nephron cells: 267.4;Spermatogenic cell types: 111.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 10.4;plasmacytoid DC: 10.6" "Group enriched" "Detected in many" 17 "dendritic cells: 10.6;monocytes: 10.4" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 13811280.5;Astrocytes and Neuropil: 20949550.1;Microglia and Neuropil: 43522745.6;Neurons: 20551884.4" "Tissue enriched" "Detected in some" "cerebral cortex: 57027761.6" "HPA003973, HPA076533" Approved "Vesicles,Lipid droplets" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 57: Podocytes - Glomerular filtration" 6 "Vesicles, Lipid droplets" "HPA003973: , HPA076533: " "unprognostic (1.91e-1)" "unprognostic (3.49e-2)" "unprognostic (4.34e-1)" "unprognostic (1.79e-1)" "unprognostic (3.23e-1)" "unprognostic (3.81e-2)" "unprognostic (2.89e-3)" "unprognostic (1.63e-1)" "unprognostic (2.25e-1)" "unprognostic (5.08e-2)" "potential prognostic favorable (4.83e-4)" "unprognostic (7.36e-2)" "unprognostic (1.59e-1)" "unprognostic (2.83e-2)" "unprognostic (5.32e-2)" "unprognostic (6.71e-3)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (2.77e-1)" "unprognostic (4.12e-2)" "unprognostic (8.73e-2)" "unprognostic (2.56e-1)" "unprognostic (1.57e-2)" "unprognostic (7.01e-2)" "unprognostic (4.10e-2)" "unprognostic (3.13e-1)" "unprognostic (9.00e-2)" "unprognostic (1.95e-1)" "unprognostic (5.39e-3)" "unprognostic (1.75e-1)" "unprognostic (1.25e-1)" "unprognostic (2.64e-1)" IQUB FLJ35834 ENSG00000164675 "IQ motif and ubiquitin domain containing" Q8NA54 7 123452193-123535077 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 31.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 92.4;Early spermatids: 255.6;Endometrial ciliated cells: 142.3;Ependymal cells: 181.7;Fallopian tube ciliated cells: 151.8;Late primary spermatocytes: 393.6;Late spermatids: 258.8;Oocytes: 119.7;Renal collecting duct principal cells: 79.9;Renal connecting tubule cells: 98.1;Respiratory ciliated cells: 222.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 222.0;Ductal cells: 98.1;Oocytes: 119.7;Spermatogenic cell types: 393.6" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 93.1;ependymal cell: 213.8" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 30058 "Fallopian tube cells: 3005849.0" "Tissue enriched" "Detected in single" 50028 "fallopian tube: 5002754.8" HPA049626 Approved "Nucleoplasm,Nuclear speckles,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 58 "Nuclear speckles, Mid piece, Principal piece, End piece" "Nucleoplasm, Cytosol" "HPA049626: " "unprognostic (2.39e-1)" "unprognostic (9.24e-2)" "potential prognostic favorable (1.04e-11)" "unprognostic (2.13e-2)" "unprognostic (1.19e-3)" "unprognostic (2.49e-1)" "unprognostic (2.32e-1)" IRAK1 "IRAK, pelle" ENSG00000184216 "Interleukin 1 receptor associated kinase 1" P51617 X 154010506-154019902 "Enzymes, Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 86.5;monocytes: 90.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB004461, HPA054476" Supported Supported Nucleoplasm,Cytosol No No "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 78 Cytosol Nucleoplasm "CAB004461: , HPA054476: " "unprognostic (1.76e-1)" "unprognostic (2.47e-3)" "unprognostic (4.54e-2)" "unprognostic (2.21e-1)" "unprognostic (3.55e-2)" "unprognostic (1.63e-1)" "unprognostic (4.56e-3)" "unprognostic (2.33e-1)" "unprognostic (3.05e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (1.12e-3)" "unprognostic (2.71e-2)" "validated prognostic unfavorable (2.10e-4)" "validated prognostic unfavorable (3.81e-4)" "unprognostic (4.42e-2)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (8.35e-2)" "unprognostic (3.59e-1)" "unprognostic (3.38e-2)" "unprognostic (7.26e-3)" "unprognostic (5.18e-2)" "unprognostic (6.69e-2)" "unprognostic (1.28e-1)" "unprognostic (1.04e-2)" "unprognostic (1.11e-2)" "unprognostic (7.81e-2)" "unprognostic (9.35e-3)" "unprognostic (1.52e-1)" "unprognostic (1.11e-3)" "unprognostic (1.09e-1)" IRAK3 IRAK-M ENSG00000090376 "Interleukin 1 receptor associated kinase 3" Q9Y616 12 66189195-66254622 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 73.8" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 996.6;Monocyte progenitors: 1316.6;monocytes: 1517.4;Neutrophil progenitors: 2381.1;Neutrophils: 9249.9" "Cell type enriched" "Detected in many" 6 "Neutrophils: 9249.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 417.8;endothelial cell: 468.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 12.7;classical monocyte: 23.5;intermediate monocyte: 24.2;myeloid DC: 11.5;neutrophil: 12.9;non-classical monocyte: 42.3" "Group enriched" "Detected in many" 12 "dendritic cells: 11.5;granulocytes: 12.9;monocytes: 42.3" "Cancer enhanced" "Detected in many" "Leukemia: 15.6" "Breast - Adipocytes (Breast), Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neutrophils: 12721117.6" "Group enriched" "Detected in some" 26421 "bone marrow: 3401151.8;lymphoid tissue: 1883100.5" HPA043097 Approved Approved Vesicles NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 Vesicles "HPA043097: " "unprognostic (1.48e-1)" "unprognostic (2.72e-1)" "unprognostic (1.07e-1)" "unprognostic (2.50e-1)" "unprognostic (3.43e-1)" "unprognostic (4.83e-2)" "unprognostic (4.61e-1)" "unprognostic (2.09e-1)" "unprognostic (3.31e-2)" "potential prognostic favorable (4.50e-4)" "unprognostic (7.90e-3)" "unprognostic (1.43e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-1)" "unprognostic (1.41e-2)" "unprognostic (6.35e-3)" "unprognostic (1.54e-2)" "unprognostic (8.43e-2)" "unprognostic (2.76e-2)" "unprognostic (2.63e-1)" "unprognostic (1.13e-1)" "unprognostic (7.30e-2)" "unprognostic (1.24e-3)" "unprognostic (1.22e-1)" "unprognostic (4.54e-2)" "unprognostic (1.18e-1)" "unprognostic (2.38e-2)" IRF1 MAR ENSG00000125347 "Interferon regulatory factor 1" P10914 5 132440440-132508719 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 134.1" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 584.9;Neutrophils: 755.6;Salivary myoepithelial cells: 620.6;Smooth muscle cells: 567.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "endothelial cell: 56.0;leukocyte: 119.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB011662, HPA063131, HPA070953" Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 20: Non-specific - Transcription regulation" 23 Nucleoplasm Cytosol "CAB011662: , HPA063131: , HPA070953: " "unprognostic (1.83e-1)" "unprognostic (8.22e-3)" "unprognostic (9.90e-2)" "unprognostic (1.66e-1)" "unprognostic (4.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.50e-1)" "unprognostic (5.67e-2)" "unprognostic (3.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.00e-1)" "unprognostic (2.03e-3)" "unprognostic (3.94e-1)" "unprognostic (3.52e-2)" "unprognostic (8.59e-2)" "unprognostic (1.94e-1)" "unprognostic (1.86e-2)" "unprognostic (4.83e-1)" "unprognostic (1.42e-1)" "unprognostic (6.33e-3)" "unprognostic (6.93e-2)" "unprognostic (1.64e-1)" "unprognostic (2.54e-1)" "unprognostic (9.29e-3)" "unprognostic (8.19e-2)" "unprognostic (1.36e-2)" "unprognostic (3.32e-2)" "unprognostic (1.81e-1)" "unprognostic (1.75e-1)" "unprognostic (1.80e-1)" IRF6 "LPS, OFC6, VWS, VWS1" ENSG00000117595 "Interferon regulatory factor 6" O14896 1 209785617-209806175 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 86.6;skin 1: 104.1" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 17.3;Ependymal cells: 6.1;Loop of henle epithelial cells: 8.7;Papillary tip epithelial cells: 39.6;Proximal tubule cells: 7.0;Renal collecting duct intercalated cells: 25.7;Renal collecting duct principal cells: 14.5;Renal connecting tubule cells: 14.2" "Group enriched" "Detected in some" 5 "Ductal cells: 25.7;Renal nephron cells: 39.6" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 7.6;endothelial cell: 8.1;ependymal cell: 7.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 20.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 108.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 6582527.2;Large ducts: 5467783.6" "Tissue enriched" "Detected in many" "lung: 11070171.6" "HPA063121, HPA076162" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 58: Skin - Keratinization" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 4 Cytosol Nucleoplasm "HPA063121: , HPA076162: " "unprognostic (1.01e-1)" "unprognostic (9.31e-2)" "unprognostic (3.20e-2)" "unprognostic (1.63e-2)" "unprognostic (1.81e-1)" "unprognostic (6.02e-2)" "unprognostic (3.09e-2)" "unprognostic (3.71e-2)" "unprognostic (4.26e-1)" "validated prognostic favorable (5.53e-10)" "validated prognostic favorable (2.79e-5)" "unprognostic (4.47e-3)" "unprognostic (1.27e-1)" "unprognostic (4.46e-3)" "unprognostic (2.92e-1)" "unprognostic (7.34e-2)" "unprognostic (2.36e-1)" "unprognostic (2.85e-1)" "unprognostic (4.18e-2)" "unprognostic (3.43e-3)" "unprognostic (1.95e-3)" "unprognostic (3.01e-1)" "unprognostic (1.53e-1)" "unprognostic (6.58e-2)" "unprognostic (8.40e-2)" "unprognostic (7.93e-3)" "unprognostic (2.17e-1)" "unprognostic (4.54e-3)" "unprognostic (1.57e-1)" "unprognostic (3.29e-1)" IRF7 ENSG00000185507 "Interferon regulatory factor 7" Q92985 11 612553-615983 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.7;lymphoid tissue: 33.5" "Cell type enriched" "Detected in many" 14 "pDCs: 790.3" "Cell type enriched" "Detected in many" 14 "dendritic cells: 790.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.1;endothelial cell: 34.4;leukocyte: 19.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 12 "plasmacytoid DC: 597.5" "Lineage enriched" "Detected in all" 12 "dendritic cells: 597.5" "Low cancer specificity" "Detected in many" "Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2723 "B-cells: 244308.8;Macrophages: 333699.3;T-cells: 238919.8" "Not detected" "Not detected" "CAB017694, HPA052757" Approved Supported Nucleoplasm,Cytosol No NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 8: Immune cells - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 40 Nucleoplasm Cytosol "CAB017694: , HPA052757: " "unprognostic (1.02e-3)" "unprognostic (3.07e-2)" "unprognostic (5.34e-2)" "unprognostic (7.67e-3)" "unprognostic (8.36e-2)" "unprognostic (2.43e-2)" "unprognostic (3.09e-1)" "unprognostic (4.49e-2)" "unprognostic (1.17e-1)" "unprognostic (7.30e-2)" "unprognostic (9.18e-2)" "unprognostic (5.63e-2)" "unprognostic (1.05e-3)" "unprognostic (4.86e-3)" "unprognostic (3.06e-3)" "unprognostic (2.11e-2)" "unprognostic (3.54e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-3)" "unprognostic (4.01e-3)" "unprognostic (4.59e-3)" "unprognostic (2.88e-2)" "unprognostic (3.82e-1)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (2.43e-1)" "unprognostic (2.52e-1)" "unprognostic (1.92e-1)" "unprognostic (2.39e-3)" "unprognostic (1.55e-2)" IRF8 "ICSBP, ICSBP1, IRF-8" ENSG00000140968 "Interferon regulatory factor 8" Q02556 16 85899116-85922606 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 195.7" "Cell type enhanced" "Detected in many" "B-cells: 389.8;cDC: 357.1;Kupffer cells: 197.8;Macrophages: 158.9;Microglia: 182.7;Monocyte progenitors: 158.1;monocytes: 151.6;pDCs: 1306.7;Thymocytes: 107.6" "Group enriched" "Detected in many" 4 "B-cells: 389.8;dendritic cells: 1306.7" "Cell type enriched" "Detected in some" 11 "central nervous system macrophage: 202.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "plasmacytoid DC: 2405.3" "Lineage enriched" "Detected in all" 7 "dendritic cells: 2405.3" "Group enriched" "Detected in many" 8 "Leukemia: 59.6;lymphoma: 187.3" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 31985031.6;Macrophages: 9637034.4;T-cells: 17569746.5" "Tissue enriched" "Detected in some" "intestine: 18528190.6" "HPA002267, HPA002531, CAB013480" Enhanced Enhanced Nucleoplasm NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 8 Nucleoplasm "CAB013480: , HPA002267: , HPA002531: " "unprognostic (2.77e-3)" "unprognostic (1.12e-2)" "unprognostic (5.75e-2)" "unprognostic (3.04e-1)" "unprognostic (2.37e-1)" "unprognostic (1.52e-3)" "unprognostic (1.82e-1)" "unprognostic (1.81e-2)" "unprognostic (3.17e-3)" "unprognostic (2.61e-1)" "unprognostic (3.29e-3)" "unprognostic (1.53e-2)" "unprognostic (8.53e-2)" "unprognostic (7.16e-2)" "unprognostic (1.14e-2)" "potential prognostic favorable (2.23e-4)" "unprognostic (3.98e-2)" "unprognostic (2.21e-1)" "unprognostic (2.86e-1)" "unprognostic (2.26e-1)" "unprognostic (2.10e-1)" "unprognostic (1.04e-1)" "unprognostic (3.42e-2)" "unprognostic (6.63e-2)" "unprognostic (1.23e-2)" "unprognostic (1.77e-1)" "unprognostic (1.08e-1)" "unprognostic (4.85e-1)" "unprognostic (2.83e-2)" "unprognostic (8.13e-2)" "unprognostic (1.62e-1)" IRS1 HIRS-1 ENSG00000169047 "Insulin receptor substrate 1" P35568 2 226731312-226799820 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 166.1;Adrenal cortex cells: 122.4;Breast lactating cells: 120.0;Renal collecting duct intercalated cells: 137.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Granulosa cells: 3039924.9" "Tissue enhanced" "Detected in many" "lung: 12006072.5;ovary: 7507038.2" "CAB005261, HPA046433" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 72: Neuronal - Signal transduction" "Cluster 89: Adipocytes - Lipid metabolism" 58 "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane" "CAB005261: , HPA046433: " "unprognostic (6.97e-3)" "unprognostic (1.09e-1)" "potential prognostic favorable (5.38e-4)" "unprognostic (5.67e-3)" "unprognostic (1.63e-1)" "unprognostic (9.98e-2)" "unprognostic (2.93e-2)" "unprognostic (5.20e-2)" "unprognostic (1.64e-1)" "unprognostic (2.05e-1)" "unprognostic (2.35e-2)" "unprognostic (2.08e-1)" "unprognostic (6.22e-2)" "unprognostic (1.29e-1)" "unprognostic (2.97e-1)" "unprognostic (3.19e-3)" "unprognostic (4.11e-3)" "unprognostic (3.82e-2)" "unprognostic (5.37e-2)" "unprognostic (9.47e-3)" "unprognostic (3.53e-2)" "unprognostic (1.40e-2)" "unprognostic (1.83e-1)" "unprognostic (5.77e-2)" "unprognostic (1.62e-1)" "unprognostic (7.72e-2)" "unprognostic (9.93e-2)" "unprognostic (3.73e-2)" "unprognostic (1.60e-1)" "unprognostic (4.50e-2)" "unprognostic (2.22e-2)" IRS2 ENSG00000185950 "Insulin receptor substrate 2" Q9Y4H2 13 109752695-109786583 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.4" "Cell type enhanced" "Detected in all" "Monocyte progenitors: 732.0;monocytes: 574.1;Neutrophil progenitors: 778.1;Neutrophils: 2931.5" "Cell type enriched" "Detected in all" 4 "Neutrophils: 2931.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1583143.5" "Group enriched" "Detected in some" 1764 "bone marrow: 192332.4;cerebral cortex: 163743.6;ovary: 173078.7" "CAB016944, HPA054664" Approved Supported Aggresome,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 36 Cytosol Aggresome "CAB016944: , HPA054664: " "unprognostic (5.53e-3)" "unprognostic (9.75e-3)" "unprognostic (6.55e-2)" "unprognostic (8.76e-3)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.53e-5)" "unprognostic (2.83e-1)" "unprognostic (1.38e-1)" "unprognostic (1.14e-2)" "unprognostic (1.04e-1)" "unprognostic (7.52e-2)" "unprognostic (9.26e-2)" "unprognostic (6.62e-2)" "unprognostic (8.72e-2)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (1.44e-2)" "unprognostic (9.42e-2)" "unprognostic (2.71e-1)" "unprognostic (4.98e-3)" "unprognostic (1.26e-3)" "unprognostic (1.73e-1)" "unprognostic (2.72e-3)" "unprognostic (8.68e-2)" "unprognostic (5.43e-2)" "unprognostic (5.56e-2)" "unprognostic (1.89e-1)" "unprognostic (2.68e-1)" "unprognostic (1.79e-1)" "unprognostic (4.13e-2)" "unprognostic (1.43e-1)" IRX5 IRX-2a ENSG00000176842 "Iroquois homeobox 5" P78411 16 54930865-54934485 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Sensory transduction, Transcription, Vision" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 13.2;skin 1: 16.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 39.4;Basal prostatic cells: 44.5;Breast hormone-responsive cells: 50.4;Breast lactating cells: 90.2;Breast myoepithelial cells: 92.1;Breast secretory cells: 36.8;Melanocytes: 36.0;Müller glia: 46.9;Respiratory basal cells: 33.7;Respiratory ciliated cells: 35.2;Respiratory deuterosomal cells: 32.1;Respiratory ionocytes: 35.6;Respiratory secretory cells: 34.7" "Cell type enhanced" "Detected in many" "Secretory cells: 90.2;Secretory gland support: 92.1" "Cell type enhanced" "Detected in some" "astrocyte: 9.4;Bergmann glia: 26.8;ependymal cell: 13.7" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 39.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "breast cancer: 21.0" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 1708 "Granulosa cells: 170843.0" "Not detected" "Not detected" HPA047130 Approved "Nuclear speckles,Microtubules,Cytosol" No NA "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" "Nuclear speckles" "Microtubules, Cytosol" "HPA047130: " "unprognostic (1.89e-1)" "unprognostic (1.81e-1)" "unprognostic (2.12e-2)" "unprognostic (2.55e-1)" "unprognostic (9.18e-2)" "unprognostic (3.18e-2)" "unprognostic (1.55e-2)" "unprognostic (1.59e-2)" "unprognostic (4.44e-3)" "unprognostic (1.43e-1)" "potential prognostic favorable (6.49e-4)" "potential prognostic favorable (1.12e-7)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" "unprognostic (1.12e-1)" "unprognostic (6.33e-2)" "unprognostic (4.85e-2)" "unprognostic (1.50e-1)" "unprognostic (2.86e-1)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (2.16e-2)" "unprognostic (1.48e-1)" "unprognostic (1.51e-1)" IRX6 "IRX-3, IRX7" ENSG00000159387 "Iroquois homeobox 6" P78412 16 55324203-55330756 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 9.2;heart muscle: 10.8;skin 1: 9.8" "Cell type enhanced" "Detected in some" "Adipocytes: 16.0;Alveolar cells type 2: 8.5;Cardiomyocytes: 34.6;Epicardial cells: 4.5;Hofbauer cells: 12.7;Late spermatids: 12.2;Ocular epithelial cells: 4.2;Retinal bipolar cells: 11.9" "Cell type enhanced" "Detected in many" "Adipocytes: 16.0;Mononuclear phagocytes: 12.7;Myocytes: 34.6;Neuronal cells: 11.9;Spermatogenic cell types: 12.2" "Cell type enhanced" "Detected in some" "medium spiny neuron: 1.4" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 11.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2;skin cancer: 4.3;thyroid cancer: 5.1" "Pituitary gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 720 "lung: 72030.2" HPA018332 Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 58: Skin - Keratinization" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 9 "Nucleoplasm, Mitochondria" "HPA018332: " "unprognostic (2.58e-3)" "unprognostic (9.80e-3)" "unprognostic (9.17e-2)" "unprognostic (9.38e-2)" "unprognostic (2.73e-3)" "unprognostic (5.79e-2)" "unprognostic (2.01e-2)" "potential prognostic favorable (5.29e-4)" "unprognostic (1.95e-1)" "unprognostic (8.88e-2)" "unprognostic (7.49e-2)" "unprognostic (2.22e-3)" "unprognostic (5.70e-2)" "unprognostic (1.03e-1)" ISOC1 CGI-111 ENSG00000066583 "Isochorismatase domain containing 1" Q96CN7 5 129094749-129114028 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 119.4;Hepatocytes: 109.3;Oocytes: 124.3;Parietal cells: 123.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 75436658.8" "Low tissue specificity" "Detected in all" HPA070307 Approved "Endoplasmic reticulum,Vesicles" NA NA 1500000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 3 "Endoplasmic reticulum, Vesicles" "HPA070307: " "unprognostic (8.15e-3)" "unprognostic (1.22e-1)" "unprognostic (2.43e-3)" "unprognostic (8.00e-2)" "unprognostic (9.49e-2)" "unprognostic (9.46e-3)" "unprognostic (1.32e-2)" "unprognostic (2.68e-1)" "unprognostic (1.05e-1)" "unprognostic (2.17e-3)" "potential prognostic favorable (1.14e-6)" "unprognostic (4.53e-2)" "unprognostic (1.25e-2)" "unprognostic (6.85e-2)" "unprognostic (3.95e-2)" "unprognostic (9.51e-2)" "unprognostic (3.35e-1)" "unprognostic (2.35e-1)" "unprognostic (5.06e-2)" "unprognostic (2.21e-1)" "unprognostic (4.92e-2)" "unprognostic (1.12e-1)" "unprognostic (2.16e-1)" "unprognostic (1.43e-1)" "unprognostic (1.44e-1)" "unprognostic (9.30e-2)" "unprognostic (1.69e-1)" "unprognostic (7.64e-2)" "unprognostic (2.32e-1)" "unprognostic (6.18e-2)" "unprognostic (1.57e-1)" ITCH AIP4 ENSG00000078747 "Itchy E3 ubiquitin protein ligase" Q96J02 20 34363235-34511773 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 103.4;Bergmann glia: 133.0;Brain excitatory neurons: 107.4;Brain inhibitory neurons: 100.6;Choroid plexus epithelial cells: 286.1;Distal convoluted tubule cells: 226.0;Ependymal cells: 107.5;Loop of henle epithelial cells: 180.7;Microglia: 187.9;Oligodendrocyte progenitor cells: 123.6;Oligodendrocytes: 360.6;Papillary tip epithelial cells: 207.9;Podocytes: 211.1;Proximal tubule cells: 258.0;Renal collecting duct intercalated cells: 194.8;Renal collecting duct principal cells: 188.9;Renal connecting tubule cells: 219.6" "Group enriched" "Detected in some" 5 "Ciliated cells: 286.1;Ductal cells: 219.6;Glial cells: 360.6;Neuronal cells: 107.4;Renal nephron cells: 258.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA021126, HPA049032, CAB072824, CAB072825" Supported Enhanced Nucleoplasm,Vesicles No No "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 62: Non-specific - Plasma proteins" "Cluster 102: Non-specific - Mixed function" 141 Nucleoplasm Vesicles "CAB072824: , CAB072825: , HPA021126: , HPA049032: " "unprognostic (3.03e-1)" "unprognostic (1.28e-1)" "unprognostic (6.92e-2)" "unprognostic (1.37e-3)" "unprognostic (3.88e-2)" "unprognostic (3.76e-1)" "unprognostic (1.61e-1)" "unprognostic (3.01e-2)" "unprognostic (3.68e-1)" "unprognostic (1.23e-2)" "validated prognostic favorable (9.00e-6)" "validated prognostic favorable (8.48e-4)" "unprognostic (2.50e-1)" "unprognostic (1.02e-1)" "unprognostic (3.63e-1)" "unprognostic (2.98e-2)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (4.96e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (3.11e-3)" "potential prognostic unfavorable (5.27e-7)" "unprognostic (4.85e-2)" "unprognostic (1.85e-3)" "unprognostic (1.24e-1)" "unprognostic (1.09e-1)" "unprognostic (6.54e-2)" "unprognostic (3.40e-1)" "unprognostic (7.67e-3)" "unprognostic (1.09e-1)" ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 500.5;Papillary tip epithelial cells: 210.3;Podocytes: 417.1;Transitional alveolar cells: 168.5;Urothelial cells: 243.2" "Cell type enhanced" "Detected in many" "Alveolar cells: 500.5;Barrier epithelial cells: 243.2;Renal nephron cells: 417.1" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Kidney - Endothelial cells, Lung - Alveolar cells type 1, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 99777703.4;Neutrophils: 89128834.9" "Low tissue specificity" "Detected in many" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Urothelial cells - Basic cellular functions" 15 "Plasma membrane" "CAB018594: , HPA008572: " "unprognostic (7.22e-2)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "unprognostic (1.78e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (4.84e-3)" "unprognostic (2.05e-3)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (2.19e-1)" "potential prognostic favorable (6.07e-4)" "unprognostic (5.51e-2)" "unprognostic (7.36e-2)" "unprognostic (3.01e-2)" "unprognostic (3.32e-3)" "unprognostic (4.09e-2)" "unprognostic (8.18e-3)" "potential prognostic unfavorable (9.31e-5)" "unprognostic (3.58e-2)" "unprognostic (3.57e-2)" "unprognostic (2.72e-1)" "validated prognostic unfavorable (1.33e-4)" "validated prognostic unfavorable (2.27e-5)" "unprognostic (1.48e-2)" "unprognostic (2.27e-1)" "unprognostic (6.81e-2)" "potential prognostic favorable (8.80e-4)" "unprognostic (1.84e-1)" "unprognostic (2.48e-1)" "unprognostic (1.45e-1)" "unprognostic (2.40e-2)" ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 343.1;lymphoid tissue: 162.7" "Cell type enhanced" "Detected in many" "cDC: 399.5;Hofbauer cells: 522.8;Kupffer cells: 222.4;Macrophages: 344.6;Monocyte progenitors: 358.2;monocytes: 613.7;Neutrophil progenitors: 309.9;Neutrophils: 726.1;NK-cells: 269.4;T-cells: 148.4" "Cell type enhanced" "Detected in many" "dendritic cells: 399.5;Mononuclear phagocytes: 613.7;Neutrophils: 726.1;NK-cells: 269.4" "Group enriched" "Detected in some" 15 "central nervous system macrophage: 126.3;leukocyte: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Bone cancer: 64.2;Leukemia: 194.5;lymphoma: 74.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neutrophils: 1148991490.9" "Tissue enhanced" "Detected in all" "bone marrow: 275267948.5;lymphoid tissue: 288864689.0" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 5100000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 34 "Plasma membrane" "Rods & Rings" "HPA008877: , HPA016894: " "unprognostic (4.81e-2)" "unprognostic (4.76e-2)" "unprognostic (2.34e-2)" "unprognostic (5.75e-2)" "unprognostic (8.94e-2)" "unprognostic (1.28e-1)" "unprognostic (5.59e-3)" "unprognostic (2.22e-1)" "unprognostic (8.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.78e-3)" "unprognostic (2.33e-1)" "unprognostic (3.55e-1)" "unprognostic (1.18e-1)" "unprognostic (2.03e-1)" "unprognostic (1.74e-1)" "unprognostic (2.15e-2)" "unprognostic (2.83e-1)" "unprognostic (1.03e-1)" "unprognostic (5.88e-2)" "unprognostic (4.43e-1)" "unprognostic (1.60e-1)" "unprognostic (9.67e-2)" "unprognostic (1.04e-1)" "unprognostic (8.46e-2)" "unprognostic (1.94e-2)" "unprognostic (1.12e-1)" "unprognostic (8.14e-2)" "unprognostic (2.13e-2)" "unprognostic (1.74e-1)" "unprognostic (1.08e-2)" ITGB5 ENSG00000082781 "Integrin subunit beta 5" P18084 3 124761948-124901418 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 290.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 223.0;Hofbauer cells: 230.0;Platelets: 419.7;Podocytes: 308.9" "Cell type enhanced" "Detected in many" "Platelets: 419.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 188.5;central nervous system macrophage: 201.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 12090530.0;Smooth muscle cells: 20473223.3" "Tissue enhanced" "Detected in many" "blood vessel: 34214144.8" "HPA001820, CAB022050" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 240000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 39 "Plasma membrane, Mitochondria" "CAB022050: , HPA001820: " "unprognostic (2.49e-1)" "unprognostic (2.43e-1)" "unprognostic (7.11e-2)" "unprognostic (2.09e-3)" "unprognostic (3.44e-1)" "unprognostic (1.10e-2)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (8.73e-4)" "potential prognostic favorable (1.99e-6)" "unprognostic (6.84e-2)" "unprognostic (5.23e-2)" "unprognostic (1.02e-3)" "unprognostic (2.80e-3)" "unprognostic (1.64e-2)" "unprognostic (1.40e-3)" "unprognostic (1.99e-2)" "unprognostic (1.42e-1)" "unprognostic (9.64e-3)" "unprognostic (2.36e-3)" "unprognostic (1.74e-3)" "unprognostic (7.93e-2)" "unprognostic (3.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.36e-2)" "unprognostic (1.11e-1)" "unprognostic (5.76e-2)" "unprognostic (1.33e-1)" "unprognostic (5.28e-2)" "unprognostic (3.48e-1)" ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.1" "Cell type enhanced" "Detected in many" "B-cells: 21.4;cDC: 16.6;Innate lymphoid cells: 35.8;NK-cells: 40.3;pDCs: 15.4;Plasma cells: 69.6;T-cells: 34.0;Thymocytes: 16.9" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 35.8;NK-cells: 40.3;Plasma cells: 69.6;T-cells: 34.0" "Cell type enriched" "Detected in some" 5 "leukocyte: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in many" 18 "Myeloma: 982.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7148 "B-cells: 435646.2;Macrophages: 877503.9;T-cells: 831251.8" "Tissue enriched" "Detected in some" "lymphoid tissue: 2056139.1" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 390000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Plasma membrane, Cytosol" "HPA042277: " "unprognostic (8.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.38e-2)" "unprognostic (9.63e-3)" "unprognostic (7.07e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (9.37e-4)" "unprognostic (1.30e-1)" "potential prognostic favorable (1.09e-4)" "unprognostic (1.40e-1)" "unprognostic (1.88e-1)" "unprognostic (4.53e-2)" "unprognostic (3.70e-3)" "potential prognostic favorable (9.95e-4)" "unprognostic (1.40e-1)" "unprognostic (1.98e-3)" "unprognostic (8.08e-2)" "unprognostic (1.99e-1)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (7.97e-3)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (1.70e-1)" "unprognostic (1.75e-1)" "unprognostic (8.16e-2)" "unprognostic (1.85e-1)" "unprognostic (1.33e-2)" "unprognostic (5.55e-1)" "unprognostic (8.27e-2)" "unprognostic (2.11e-2)" "unprognostic (7.71e-2)" ITIH2 H2P ENSG00000151655 "Inter-alpha-trypsin inhibitor heavy chain 2" P19823 10 7703316-7749520 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 561 "liver: 2016.4" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 538.8" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 538.8" "Cell type enriched" "Detected in many" 29 "fibroblast: 184.1" "Cancer enriched" "Detected in many" 258 "Liver Hepatocellular Carcinoma (TCGA): 850.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 40 "liver cancer: 147.1" "Liver - Hepatocytes, Pituitary gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cell types: 179277291.6" "Low tissue specificity" "Detected in all" HPA059150 Supported Approved "Golgi apparatus" "Secreted to blood" "Enzyme inhibitor" NA NA 62000000000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 16: Non-specific - Transcription" "Cluster 18: Liver cancer - Metabolism" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 13 "Golgi apparatus" "HPA059150: " "unprognostic (1.34e-1)" "unprognostic (7.51e-2)" "unprognostic (4.93e-2)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (2.04e-3)" "unprognostic (1.67e-2)" "unprognostic (1.93e-1)" "unprognostic (7.79e-2)" "unprognostic (1.45e-2)" "unprognostic (1.21e-1)" "unprognostic (1.39e-2)" "unprognostic (3.89e-3)" "unprognostic (1.66e-1)" "unprognostic (5.31e-3)" ITLN1 "FLJ20022, hIntL, HL-1, ITLN, LFR" ENSG00000179914 "Intelectin 1" Q8WWA0 1 160876540-160885180 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 714.6;intestine: 1172.6" "Cell type enriched" "Detected in some" 4 "Mesothelial cells: 8631.6" "Cell type enriched" "Detected in many" 4 "Barrier epithelial cells: 8631.6" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 87.3;Lung Adenocarcinoma (TCGA): 53.0;Pancreatic Adenocarcinoma (TCGA): 73.5;Rectum Adenocarcinoma (TCGA): 117.2;Stomach Adenocarcinoma (TCGA): 56.5" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "intermediate monocyte: 9.2;non-classical monocyte: 24.2" "Lineage enriched" "Detected in many" 17 "monocytes: 24.2" "Cancer enhanced" "Detected in some" "Gastric cancer: 1.8;Leukemia: 1.4;liver cancer: 1.3" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Group enriched" "Detected in some" "Alveolar cell types: 1835951.2;Smooth muscle cells: 5104332.5" "Tissue enriched" "Detected in many" "intestine: 584136853.8" "CAB012652, HPA063275, HPA067326" Enhanced Approved "Vesicles,Acrosome,Equatorial segment,Mid piece,Principal piece" "Secreted to blood" "No annotated function" NA NA 294000000 5200000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 47: Leukemia - Hemostasis" "Cluster 70: Intestinal goblet cells - Mucin production" 39 "Vesicles, Equatorial segment" "Acrosome, Mid piece, Principal piece" "CAB012652: , HPA063275: , HPA067326: " "unprognostic (1.71e-1)" "unprognostic (2.25e-3)" "unprognostic (4.86e-2)" "unprognostic (1.42e-1)" "unprognostic (1.70e-2)" "unprognostic (1.11e-1)" "unprognostic (7.84e-3)" "unprognostic (2.85e-1)" "unprognostic (1.86e-2)" "unprognostic (1.01e-3)" "unprognostic (7.41e-2)" "unprognostic (1.09e-1)" "unprognostic (3.55e-1)" "unprognostic (1.60e-1)" "unprognostic (1.18e-1)" ITPA "C20orf37, dJ794I6.3, HLC14-06-P" ENSG00000125877 "Inosine triphosphatase" Q9BY32 20 3208868-3223870 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 3337211.0" "Low tissue specificity" "Detected in many" "HPA022824, HPA073963" Approved Supported Nucleoplasm,Cytosol NA NA 50000 "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 97: Non-specific - Cellular respiration" 6 "Nucleoplasm, Cytosol" "HPA022824: , HPA073963: " "unprognostic (4.80e-2)" "unprognostic (3.13e-1)" "unprognostic (4.56e-2)" "unprognostic (7.69e-3)" "unprognostic (2.57e-1)" "unprognostic (6.52e-2)" "unprognostic (1.02e-1)" "unprognostic (2.22e-2)" "unprognostic (6.60e-2)" "unprognostic (2.24e-1)" "unprognostic (2.93e-3)" "potential prognostic unfavorable (6.41e-4)" "unprognostic (5.68e-2)" "validated prognostic unfavorable (4.24e-6)" "validated prognostic unfavorable (6.03e-5)" "unprognostic (1.82e-2)" "unprognostic (4.90e-2)" "unprognostic (6.64e-3)" "unprognostic (1.15e-1)" "unprognostic (1.11e-1)" "unprognostic (7.61e-2)" "unprognostic (6.95e-2)" "unprognostic (3.73e-1)" "unprognostic (4.97e-1)" "unprognostic (2.16e-1)" "unprognostic (2.94e-2)" "unprognostic (1.57e-1)" "unprognostic (9.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.99e-1)" "unprognostic (9.75e-2)" ITPK1 ENSG00000100605 "Inositol-tetrakisphosphate 1-kinase" Q13572 14 92936914-93116320 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Isomerase, Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 190.5" "Cell type enhanced" "Detected in some" "Astrocytes: 64.8;Bergmann glia: 162.8;Brain excitatory neurons: 46.6;Brain inhibitory neurons: 42.4;Choroid plexus epithelial cells: 81.9;Distal convoluted tubule cells: 50.5;Loop of henle epithelial cells: 62.7;Microglia: 80.5;Oligodendrocyte progenitor cells: 54.6;Oligodendrocytes: 89.0;Other brain neurons: 38.6;Papillary tip epithelial cells: 56.5;Proximal tubule cells: 64.1;Renal collecting duct intercalated cells: 126.5;Renal collecting duct principal cells: 183.9;Renal connecting tubule cells: 89.2" "Group enriched" "Detected in many" 9 "Ciliated cells: 81.9;Ductal cells: 183.9;Glial cells: 162.8;Neuronal cells: 46.6;Renal nephron cells: 64.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 43.1" "Group enriched" "Detected in all" 5 "granulocytes: 43.1;monocytes: 26.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 2855091.9;Granulosa cells: 1396367.8;Microglia and Neuropil: 5389326.0;Neurons: 4507477.0" "Tissue enhanced" "Detected in many" "cerebral cortex: 1641528.3" HPA055230 Approved Approved Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 102: Non-specific - Mixed function" 1 Mitochondria "HPA055230: " "unprognostic (8.46e-2)" "unprognostic (5.11e-2)" "unprognostic (4.49e-2)" "unprognostic (5.06e-2)" "unprognostic (7.98e-2)" "unprognostic (5.00e-2)" "unprognostic (4.37e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.77e-1)" "potential prognostic favorable (3.27e-5)" "unprognostic (4.36e-2)" "unprognostic (2.38e-2)" "unprognostic (3.46e-2)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (2.01e-1)" "unprognostic (8.44e-2)" "unprognostic (2.69e-1)" "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" "unprognostic (2.14e-1)" "unprognostic (9.70e-2)" "unprognostic (1.40e-1)" "unprognostic (1.52e-1)" "unprognostic (2.65e-1)" "unprognostic (2.44e-1)" "unprognostic (7.50e-2)" "unprognostic (2.75e-1)" "unprognostic (2.15e-1)" "unprognostic (7.88e-2)" ITPKB "IP3-3KB, IP3KB" ENSG00000143772 "Inositol-trisphosphate 3-kinase B" P27987 1 226631690-226739323 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.8;choroid plexus: 90.2" "Cell type enhanced" "Detected in many" "Astrocytes: 373.3;Bergmann glia: 212.0;Choroid plexus epithelial cells: 888.6;Distal convoluted tubule cells: 420.3;Ependymal cells: 306.7;Mast cells: 175.9;T-cells: 190.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 888.6;Glial cells: 373.3;Renal nephron cells: 420.3" "Cell type enhanced" "Detected in many" "astrocyte: 600.5;choroid plexus epithelial cell: 637.3" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 87.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "skin cancer: 44.9" "Minor Salivary Gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1566521.8;T-cells: 1603645.8" "Tissue enhanced" "Detected in many" "intestine: 1583920.7" "HPA030273, HPA072923" Enhanced Approved Nucleoplasm NA NA 11000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 9 Nucleoplasm "HPA030273: , HPA072923: " "unprognostic (2.57e-3)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "unprognostic (2.55e-3)" "unprognostic (2.46e-1)" "unprognostic (1.84e-2)" "unprognostic (2.25e-1)" "unprognostic (3.34e-3)" "unprognostic (5.52e-3)" "unprognostic (1.15e-1)" "validated prognostic favorable (7.25e-6)" "validated prognostic favorable (2.37e-4)" "unprognostic (2.75e-2)" "unprognostic (7.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.16e-2)" "unprognostic (1.50e-1)" "unprognostic (4.16e-2)" "unprognostic (1.93e-3)" "unprognostic (4.82e-2)" "unprognostic (6.74e-2)" "unprognostic (8.45e-2)" "unprognostic (2.76e-1)" "unprognostic (5.91e-2)" "unprognostic (1.86e-2)" "unprognostic (5.68e-3)" "unprognostic (4.39e-1)" "unprognostic (1.55e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-2)" "unprognostic (3.10e-1)" ITPKC "IP3-3KC, IP3KC" ENSG00000086544 "Inositol-trisphosphate 3-kinase C" Q96DU7 19 40717112-40740860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 94.0" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 571.2;Esophageal apical cells: 1076.2;Esophageal suprabasal cells: 758.4;Fallopian secretory cells: 501.3;Ocular epithelial cells: 995.4;Prostatic hillock cells: 473.9;Respiratory basal cells: 736.5;Salivary acinar cells: 598.1;Suprabasal keratinocytes: 676.5;Urothelial cells: 916.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1076.2;Barrier epithelial cells: 995.4;Basal cells: 736.5;Suprabasal cells: 758.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Colon - Neutrophils, Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 32118.0;Fallopian tube cells: 41372.8" "Group enriched" "Detected in some" 1082 "lymphoid tissue: 170450.0;salivary gland: 45904.3" "HPA050760, HPA053003" Approved Supported "Nuclear speckles" No No "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 2 "Nuclear speckles" "HPA050760: , HPA053003: " "unprognostic (7.52e-2)" "unprognostic (1.45e-1)" "unprognostic (1.64e-1)" "unprognostic (1.69e-1)" "unprognostic (7.08e-2)" "unprognostic (1.54e-2)" "unprognostic (1.95e-2)" "unprognostic (1.63e-1)" "unprognostic (1.97e-1)" "unprognostic (7.30e-3)" "unprognostic (6.42e-2)" "unprognostic (9.32e-3)" "unprognostic (1.98e-1)" "unprognostic (5.41e-2)" "unprognostic (2.67e-1)" "unprognostic (2.32e-3)" "unprognostic (7.91e-2)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (9.68e-4)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (8.55e-4)" "unprognostic (1.46e-3)" "unprognostic (1.73e-1)" "unprognostic (6.74e-2)" "unprognostic (1.34e-3)" "unprognostic (4.04e-1)" "unprognostic (3.13e-1)" "unprognostic (7.76e-2)" "unprognostic (6.61e-2)" "unprognostic (1.53e-3)" ITPR1 "ACV, Insp3r1, IP3R1, PPP1R94, SCA15, SCA16, SCA29" ENSG00000150995 "Inositol 1,4,5-trisphosphate receptor type 1" Q14643 3 4493345-4847506 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 556.3;Choroid plexus epithelial cells: 718.2;Distal convoluted tubule cells: 893.4;Gonadotrophs: 1021.3;Pituitary stem cells: 648.3;Retinal pigment epithelial cells: 524.3;Salivary myoepithelial cells: 586.3" "Cell type enhanced" "Detected in all" "Pituitary endocrine cells: 1021.3;Renal nephron cells: 893.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 27.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Region enhanced" "Detected in all" "cerebellum: 697.2" "Region enhanced" "Detected in all" "cerebellum: 273.5" "Cell type enhanced" "Detected in many" "Neurons: 74585975.1;Smooth muscle cells: 69992832.0" "Tissue enhanced" "Detected in many" "cerebral cortex: 71976220.1" "HPA014765, HPA016487" Approved Uncertain Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 28 Vesicles "HPA014765: , HPA016487: " "unprognostic (3.34e-1)" "unprognostic (8.92e-2)" "unprognostic (5.14e-1)" "potential prognostic unfavorable (5.26e-5)" "unprognostic (1.46e-1)" "unprognostic (1.49e-1)" "unprognostic (1.91e-1)" "unprognostic (1.07e-1)" "unprognostic (2.28e-1)" "unprognostic (1.43e-2)" "potential prognostic favorable (2.27e-4)" "unprognostic (1.68e-2)" "unprognostic (2.18e-1)" "unprognostic (8.54e-2)" "unprognostic (3.30e-3)" "unprognostic (2.16e-1)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (2.58e-2)" "unprognostic (6.76e-3)" "unprognostic (5.64e-2)" "unprognostic (1.00e-1)" "unprognostic (5.84e-2)" "unprognostic (2.14e-1)" "unprognostic (1.12e-1)" "unprognostic (1.51e-2)" "unprognostic (6.37e-2)" "unprognostic (6.61e-2)" "unprognostic (1.71e-1)" "unprognostic (2.32e-3)" "unprognostic (1.52e-1)" ITPR3 IP3R3 ENSG00000096433 "Inositol 1,4,5-trisphosphate receptor type 3" Q14573 6 33620365-33696574 "Human disease related genes, Plasma proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Ligand-gated ion channel, Receptor" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 120.5;Alveolar cells type 2: 135.6;Early spermatids: 175.5;Foveolar cells: 220.8;Late spermatids: 339.9;Sertoli cells: 176.3" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 220.8;Spermatogenic cell types: 339.9" "Group enriched" "Detected in many" 4 "endothelial cell: 100.5;fibroblast: 28.7;leukocyte: 41.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 38321124.7" "Tissue enriched" "Detected in many" "lung: 40370175.4" "HPA003915, HPA064704" Approved Approved Vesicles,Cytosol No Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 77: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 37 Vesicles Cytosol "HPA003915: , HPA064704: " "unprognostic (7.10e-2)" "unprognostic (9.17e-2)" "unprognostic (1.70e-1)" "unprognostic (1.20e-2)" "unprognostic (2.46e-1)" "unprognostic (2.86e-2)" "unprognostic (1.66e-2)" "unprognostic (7.67e-2)" "unprognostic (1.77e-1)" "unprognostic (1.08e-2)" "unprognostic (1.07e-2)" "unprognostic (1.19e-1)" "unprognostic (3.37e-1)" "unprognostic (2.38e-2)" "unprognostic (2.87e-2)" "unprognostic (1.48e-1)" "unprognostic (4.31e-1)" "unprognostic (1.45e-1)" "unprognostic (1.36e-2)" "unprognostic (6.85e-2)" "unprognostic (2.56e-1)" "unprognostic (5.38e-3)" "unprognostic (9.28e-3)" "unprognostic (5.26e-1)" "unprognostic (1.76e-3)" "unprognostic (3.43e-2)" "unprognostic (2.39e-1)" "unprognostic (9.92e-2)" "unprognostic (1.67e-1)" "unprognostic (4.58e-2)" "unprognostic (6.07e-2)" IVD "ACAD2, IVDH" ENSG00000128928 "Isovaleryl-CoA dehydrogenase" P26440 15 40405485-40435947 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 170.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 170.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "liver: 254693044.6" "HPA041391, HPA044250" Enhanced Supported Nucleoplasm,Mitochondria NA NA 5600 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 19 Mitochondria Nucleoplasm "HPA041391: , HPA044250: " "unprognostic (4.87e-3)" "unprognostic (4.27e-2)" "unprognostic (3.32e-1)" "unprognostic (3.10e-2)" "unprognostic (1.18e-1)" "unprognostic (2.28e-1)" "unprognostic (4.60e-2)" "unprognostic (4.95e-2)" "unprognostic (7.79e-2)" "unprognostic (1.75e-1)" "validated prognostic favorable (4.85e-6)" "validated prognostic favorable (1.89e-7)" "unprognostic (8.80e-3)" "potential prognostic favorable (2.01e-4)" "unprognostic (3.58e-2)" "potential prognostic favorable (2.25e-4)" "unprognostic (1.94e-1)" "unprognostic (1.59e-1)" "unprognostic (6.36e-2)" "unprognostic (2.39e-2)" "unprognostic (1.36e-1)" "unprognostic (8.04e-2)" "unprognostic (2.94e-1)" "unprognostic (9.26e-2)" "unprognostic (5.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.89e-1)" "unprognostic (1.33e-1)" "unprognostic (2.71e-1)" "unprognostic (5.53e-2)" "unprognostic (3.04e-2)" IVL ENSG00000163207 Involucrin P07476 1 152908546-152911886 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 195.7;esophagus: 294.3;salivary gland: 84.6;skin 1: 156.4;vagina: 223.1" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 3166.6;Esophageal suprabasal cells: 1049.9" "Group enriched" "Detected in some" 15 "Apical squamous epithelial cells: 3166.6;Suprabasal cells: 1049.9" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bladder Urothelial Carcinoma (TCGA): 109.0;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 100.2;Head and Neck Squamous Cell Carcinoma (TCGA): 234.7;Skin Cutaneous Melanoma (TCGA): 112.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 46.5;head and neck cancer: 43.5" "Prostate - Urothelial cells" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 917724 "Keratinocytes: 91772393.2" "Tissue enriched" "Detected in all" "skin: 217565189.5" "CAB002243, HPA055211" Enhanced Supported "Nuclear bodies,Centrosome,Cytosol" NA NA 2900000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 33 Cytosol "Nuclear bodies, Centrosome" "CAB002243: , HPA055211: " "unprognostic (1.13e-1)" "unprognostic (4.38e-1)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (1.82e-1)" "unprognostic (6.35e-2)" "unprognostic (1.47e-1)" "unprognostic (1.96e-2)" "unprognostic (3.05e-2)" "unprognostic (1.07e-2)" "unprognostic (2.49e-1)" "unprognostic (2.69e-1)" "unprognostic (3.57e-1)" "unprognostic (1.21e-2)" "unprognostic (8.84e-2)" IZUMO3 "bA20A20.1, C9orf134" ENSG00000205442 "IZUMO family member 3" Q5VZ72 9 24542952-24545946 "Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 130 "testis: 12.9" "Group enriched" "Detected in some" 69 "Early spermatids: 211.8;Late primary spermatocytes: 189.0;Late spermatids: 142.5" "Cell type enriched" "Detected in some" 124 "Spermatogenic cell types: 211.8" "Cell type enriched" "Detected in some" 5 "lower rhombic lip: 8.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 17 "Sarcoma: 5.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045722 Approved "Acrosome,Equatorial segment" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Acrosome, Equatorial segment" "HPA045722: " IZUMO4 C19orf36 ENSG00000099840 "IZUMO family member 4" Q1ZYL8 19 2096429-2099593 "Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 23 "testis: 430.4" "Group enriched" "Detected in many" 21 "Early spermatids: 1650.2;Late primary spermatocytes: 2332.3;Late spermatids: 4016.7" "Cell type enriched" "Detected in many" 71 "Spermatogenic cell types: 4016.7" "Cell type enhanced" "Detected in all" "astrocyte: 34.8;Bergmann glia: 55.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "lymphoma: 10.8;Myeloma: 6.9;Rhabdoid: 2.9" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA048496 Enhanced Approved "Equatorial segment,Calyx,Connecting piece" "Secreted in male reproductive system" "No annotated function" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Equatorial segment, Calyx, Connecting piece" "HPA048496: " "unprognostic (9.63e-2)" "unprognostic (8.09e-3)" "unprognostic (1.65e-2)" "unprognostic (2.38e-2)" "unprognostic (3.16e-1)" "unprognostic (7.12e-3)" "unprognostic (3.09e-1)" "unprognostic (1.23e-2)" "unprognostic (3.72e-1)" "unprognostic (3.31e-2)" "unprognostic (2.26e-2)" "unprognostic (3.40e-2)" "unprognostic (3.94e-3)" "unprognostic (7.00e-2)" "unprognostic (9.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.77e-2)" "unprognostic (1.47e-2)" "unprognostic (3.78e-3)" "unprognostic (1.78e-1)" "unprognostic (1.74e-1)" "unprognostic (7.42e-2)" "unprognostic (1.46e-1)" "unprognostic (6.69e-2)" JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 371.0;Myonuclei: 421.3;Neutrophil progenitors: 438.8;Neutrophils: 666.3" "Cell type enhanced" "Detected in all" "Neutrophils: 666.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 133.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 133.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 984544.9;Oocytes: 1053578.9" "Group enriched" "Detected in some" "lung: 1559148.0;lymphoid tissue: 1072044.2" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - Proteolysis" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 44 Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: , HPA040820: , HPA043870: " "unprognostic (2.70e-2)" "unprognostic (5.40e-3)" "unprognostic (1.83e-1)" "unprognostic (2.05e-1)" "unprognostic (3.78e-2)" "unprognostic (2.35e-1)" "unprognostic (1.42e-1)" "unprognostic (1.00e-1)" "unprognostic (6.81e-3)" "unprognostic (2.82e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (1.09e-1)" "unprognostic (2.43e-3)" "unprognostic (2.89e-1)" "unprognostic (3.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.70e-2)" "unprognostic (9.49e-2)" "unprognostic (2.15e-1)" "unprognostic (6.38e-3)" "unprognostic (7.43e-2)" "unprognostic (1.49e-1)" "unprognostic (5.42e-2)" "unprognostic (3.80e-2)" "unprognostic (8.10e-3)" "unprognostic (4.82e-2)" "unprognostic (5.27e-2)" "unprognostic (2.30e-2)" "unprognostic (1.77e-1)" "unprognostic (5.43e-2)" "unprognostic (9.78e-3)" JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 40.7;lymphoid tissue: 64.8" "Cell type enhanced" "Detected in many" "cDC: 419.8;Hematopoietic stem cells: 70.4;Innate lymphoid cells: 120.2;Macrophages: 136.8;monocytes: 203.1;Neutrophils: 649.0;pDCs: 284.8;T-cells: 160.5" "Cell type enhanced" "Detected in many" "dendritic cells: 419.8;Mononuclear phagocytes: 203.1;Neutrophils: 649.0;T-cells: 160.5" "Cell type enriched" "Detected in some" 7 "leukocyte: 106.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in all" "eosinophil: 3539.1" "Group enriched" "Detected in all" 5 "dendritic cells: 1018.9;granulocytes: 3539.1;monocytes: 1025.5" "Group enriched" "Detected in some" 11 "Leukemia: 7.5;lymphoma: 18.0" "Adipose subcutaneous - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - Neutrophils_2, Stomach - T-cells, Thyroid gland - T-cells" "Region enriched" "Detected in many" 11 "cerebellum: 63.6" "Cell type enriched" "Detected in some" "Neutrophils: 7294782.0" "Tissue enriched" "Detected in some" "lung: 2592035.8" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1000000 "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: " "unprognostic (7.91e-3)" "unprognostic (2.20e-2)" "unprognostic (2.63e-3)" "unprognostic (8.83e-2)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (3.75e-5)" "unprognostic (2.31e-1)" "potential prognostic favorable (6.22e-4)" "unprognostic (4.34e-2)" "unprognostic (1.46e-2)" "unprognostic (1.05e-1)" "unprognostic (3.54e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (6.64e-4)" "unprognostic (8.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.19e-1)" "unprognostic (3.94e-1)" "unprognostic (6.06e-2)" "unprognostic (8.68e-2)" "unprognostic (3.52e-2)" "unprognostic (4.46e-1)" "unprognostic (9.35e-2)" "unprognostic (1.22e-2)" "unprognostic (6.91e-2)" "unprognostic (4.65e-2)" "unprognostic (4.25e-2)" "unprognostic (1.49e-2)" "unprognostic (1.93e-1)" JMJD1C "DKFZp761F0118, FLJ14374, KDM3C, KIAA1380, TRIP8" ENSG00000171988 "Jumonji domain containing 1C" Q15652 10 63167221-63521850 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 2309.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 14.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 155745.8;Macrophages: 144238.9;Neurons: 42381.3" "Tissue enriched" "Detected in single" 7274 "lymphoid tissue: 727383.3" "HPA056175, HPA066195" Approved Supported Nucleoplasm,Cytosol No No "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 11 Nucleoplasm Cytosol "HPA056175: , HPA066195: " "unprognostic (2.60e-1)" "unprognostic (3.41e-2)" "unprognostic (1.75e-1)" "unprognostic (1.09e-2)" "unprognostic (8.57e-2)" "unprognostic (7.35e-3)" "unprognostic (1.44e-2)" "potential prognostic favorable (1.09e-4)" "unprognostic (9.55e-2)" "unprognostic (8.06e-3)" "validated prognostic favorable (3.47e-6)" "validated prognostic favorable (2.66e-4)" "unprognostic (7.40e-2)" "unprognostic (1.06e-1)" "unprognostic (3.27e-3)" "unprognostic (1.81e-1)" "unprognostic (1.53e-1)" "unprognostic (4.86e-2)" "unprognostic (9.74e-2)" "unprognostic (3.60e-3)" "unprognostic (2.52e-2)" "unprognostic (2.73e-3)" "unprognostic (1.21e-2)" "unprognostic (1.91e-1)" "unprognostic (3.02e-2)" "unprognostic (4.96e-2)" "unprognostic (2.21e-1)" "unprognostic (2.83e-1)" "unprognostic (2.80e-1)" "unprognostic (5.72e-3)" "unprognostic (3.62e-1)" JMJD6 "KIAA0585, PTDSR, PTDSR1" ENSG00000070495 "Jumonji domain containing 6, arginine demethylase and lysine hydroxylase" Q6NYC1 17 76712832-76726799 "Essential proteins, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, Dioxygenase, Oxidoreductase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.0" "Cell type enhanced" "Detected in all" "Neutrophils: 294.8" "Cell type enhanced" "Detected in all" "Neutrophils: 294.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1600560.2" "Tissue enhanced" "Detected in many" "lung: 699766.8" "CAB004548, HPA059156, HPA074031" Supported Supported Nucleoplasm No No 8900 "Cluster 25: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 63 Nucleoplasm "CAB004548: , HPA059156: , HPA074031: " "unprognostic (4.09e-1)" "unprognostic (7.62e-3)" "unprognostic (1.34e-1)" "unprognostic (7.16e-2)" "unprognostic (3.72e-1)" "unprognostic (1.68e-1)" "unprognostic (4.62e-2)" "unprognostic (4.45e-2)" "unprognostic (1.72e-3)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "unprognostic (3.57e-2)" "potential prognostic unfavorable (1.52e-4)" "validated prognostic unfavorable (5.74e-6)" "validated prognostic unfavorable (4.85e-5)" "unprognostic (2.31e-2)" "potential prognostic unfavorable (5.49e-5)" "unprognostic (1.78e-1)" "unprognostic (2.66e-2)" "unprognostic (1.68e-1)" "unprognostic (7.45e-2)" "unprognostic (2.50e-2)" "unprognostic (1.27e-3)" "unprognostic (3.04e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (5.49e-2)" "unprognostic (2.38e-1)" "unprognostic (9.41e-2)" "unprognostic (1.76e-2)" "unprognostic (2.45e-1)" JPH3 "CAGL237, HDL2, JP-3, JP3, TNRC22" ENSG00000154118 "Junctophilin 3" Q8WXH2 16 87601835-87698156 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 112.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 62.5;Brain inhibitory neurons: 47.8;Cone photoreceptor cells: 39.3;Early spermatids: 62.8;Gonadotrophs: 22.9;Lactotrophs: 25.4;Oligodendrocyte progenitor cells: 21.7;Oocytes: 50.7;Other brain neurons: 49.2;Retinal amacrine cells: 51.5;Retinal bipolar cells: 46.3;Retinal horizontal cells: 42.1;Rod photoreceptor cells: 25.9;Somatotrophs: 30.5;Thyrotrophs: 25.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 31.9;Neuronal cells: 62.5;Oocytes: 50.7;Pituitary endocrine cells: 30.5;Spermatogenic cell types: 62.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.6;Ovary Serous Cystadenocarcinoma (TCGA): 5.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 5.8;Neuroblastoma: 6.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Microglia and Neuropil: 425212.1;Neurons: 906894.0;Oocytes: 1392749.5" "Tissue enriched" "Detected in single" 6961 "cerebral cortex: 696119.8" HPA076304 Approved Nucleoplasm,Cytosol Yes No "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 146 Nucleoplasm Cytosol "HPA076304: " "unprognostic (1.39e-1)" "unprognostic (3.12e-1)" "potential prognostic favorable (4.26e-4)" "unprognostic (2.45e-1)" "unprognostic (7.48e-3)" "unprognostic (2.08e-1)" JPT1 "ARM2, HN1, HN1A" ENSG00000189159 "Jupiter microtubule associated homolog 1" Q9UK76 17 75135248-75168281 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 394.7" "Cell type enhanced" "Detected in many" "Early spermatids: 1314.5;Esophageal apical cells: 1438.3;Esophageal suprabasal cells: 1069.5;Extravillous trophoblasts: 2151.7;Gastric progenitor cells: 975.4;Late primary spermatocytes: 2043.7;Late spermatids: 1773.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1438.3;Spermatogenic cell types: 2043.7;Suprabasal cells: 1069.5;Trophoblast cells: 2151.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 773.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 2209597.3;Granulosa cells: 2286149.3" "Tissue enhanced" "Detected in many" "cerebral cortex: 38546537.9" "HPA011097, HPA059729, HPA076731" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Cytosol" Yes NA 41000 "Cluster 7: Non-specific - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 Cytosol "Nucleoplasm, Microtubules, Cytokinetic bridge" "HPA011097: , HPA059729: , HPA076731: " "unprognostic (1.88e-3)" "unprognostic (5.97e-3)" "unprognostic (1.67e-1)" "potential prognostic favorable (7.89e-4)" "unprognostic (2.90e-1)" "unprognostic (8.84e-2)" "unprognostic (3.28e-3)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (8.16e-3)" "validated prognostic unfavorable (2.16e-7)" "validated prognostic unfavorable (6.88e-5)" "unprognostic (2.10e-3)" "potential prognostic unfavorable (5.87e-9)" "unprognostic (3.19e-3)" "unprognostic (6.93e-3)" "unprognostic (1.66e-1)" "unprognostic (9.68e-2)" "unprognostic (1.17e-2)" "unprognostic (3.20e-1)" "unprognostic (3.80e-3)" "unprognostic (2.16e-1)" "unprognostic (3.82e-2)" "unprognostic (9.85e-2)" "unprognostic (1.73e-1)" "unprognostic (7.82e-2)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (1.74e-2)" "unprognostic (6.71e-2)" JRK "jerky, JH8" ENSG00000234616 "Jrk helix-turn-helix protein" O75564 8 142657460-142681968 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 2078345.3" "Not detected" "Not detected" HPA052675 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" No No "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 1 "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA052675: " "unprognostic (1.04e-1)" "unprognostic (6.87e-3)" "unprognostic (6.52e-2)" "unprognostic (4.36e-2)" "unprognostic (3.86e-2)" "unprognostic (2.61e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (5.51e-2)" "unprognostic (3.26e-2)" "unprognostic (1.02e-3)" "unprognostic (1.16e-3)" "unprognostic (1.14e-1)" "unprognostic (3.92e-3)" "unprognostic (2.73e-1)" "unprognostic (7.81e-2)" "unprognostic (9.64e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-1)" "unprognostic (8.85e-3)" "unprognostic (2.79e-1)" "unprognostic (9.41e-2)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (1.18e-1)" "unprognostic (2.47e-1)" "unprognostic (3.71e-2)" "unprognostic (1.80e-1)" "unprognostic (2.34e-1)" "unprognostic (1.61e-1)" "unprognostic (1.06e-2)" "unprognostic (2.28e-1)" JRKL HHMJG ENSG00000183340 "JRK like" Q9Y4A0 11 96389989-96507574 "Plasma proteins, Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 327.0;Late primary spermatocytes: 70.6;Late spermatids: 128.3" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 327.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046184, HPA060341" Uncertain Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm "Cytokinetic bridge" "HPA046184: , HPA060341: " "unprognostic (3.62e-3)" "unprognostic (5.57e-3)" "unprognostic (3.77e-2)" "unprognostic (3.97e-3)" "unprognostic (3.30e-2)" "unprognostic (3.09e-1)" "unprognostic (6.81e-2)" "unprognostic (9.99e-2)" "unprognostic (2.27e-1)" "unprognostic (2.20e-1)" "potential prognostic favorable (6.84e-4)" "unprognostic (3.70e-2)" "unprognostic (2.72e-2)" "unprognostic (1.32e-3)" "unprognostic (3.29e-1)" "unprognostic (6.64e-3)" "potential prognostic unfavorable (9.22e-4)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (2.73e-2)" "unprognostic (7.10e-2)" "unprognostic (1.85e-2)" "unprognostic (6.74e-2)" "unprognostic (1.17e-1)" "unprognostic (1.84e-2)" "unprognostic (1.28e-1)" "unprognostic (1.52e-2)" "unprognostic (9.46e-2)" "unprognostic (2.66e-1)" "unprognostic (8.49e-2)" "unprognostic (6.34e-2)" JUN "AP-1, c-Jun" ENSG00000177606 "Jun proto-oncogene, AP-1 transcription factor subunit" P05412 1 58776845-58784048 "Cancer-related genes, FDA approved drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 3947.7;Epididymal principal cells: 3795.9;Ovarian stromal cells: 4609.4;Pancreatic duct cells: 3632.0" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "astrocyte: 239.9;endothelial cell: 299.8;vascular associated smooth muscle cell: 260.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Keratinocytes: 25092.7;Large ducts: 20194.4" "Tissue enriched" "Detected in some" "intestine: 1203884.1" "CAB003801, CAB007780, HPA059474, HPA066898, CAB080216, CAB080219, CAB080220" Enhanced Enhanced Nucleoplasm Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" 202 Nucleoplasm "CAB003801: , CAB007780: , CAB080216: , CAB080219: , CAB080220: , HPA059474: , HPA066898: " "unprognostic (1.36e-2)" "unprognostic (9.79e-2)" "unprognostic (8.33e-2)" "unprognostic (4.53e-2)" "unprognostic (3.67e-2)" "unprognostic (2.01e-2)" "unprognostic (1.54e-1)" "unprognostic (3.08e-1)" "unprognostic (2.91e-2)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.22e-4)" "unprognostic (2.36e-1)" "unprognostic (2.68e-2)" "unprognostic (1.81e-3)" "unprognostic (2.71e-2)" "unprognostic (2.26e-1)" "unprognostic (1.31e-1)" "unprognostic (2.39e-2)" "unprognostic (3.61e-1)" "unprognostic (1.59e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-1)" "unprognostic (1.36e-1)" "unprognostic (1.31e-2)" "unprognostic (2.01e-1)" "unprognostic (2.48e-2)" "unprognostic (4.66e-1)" "unprognostic (1.15e-1)" "unprognostic (1.39e-1)" JUND AP-1 ENSG00000130522 "JunD proto-oncogene, AP-1 transcription factor subunit" P17535 19 18279694-18281622 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 2148.7;Mast cells: 1959.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 49434.9;Neurons: 176866.3;T-cells: 159007.0" "Tissue enriched" "Detected in some" "ovary: 2412031.2" "CAB005268, HPA063029, HPA068905" Supported Enhanced Nucleoplasm No No "Cluster 7: Non-specific - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 20: Non-specific - Transcription regulation" 35 Nucleoplasm "CAB005268: , HPA063029: , HPA068905: " "unprognostic (7.21e-3)" "potential prognostic favorable (8.05e-4)" "unprognostic (7.91e-2)" "unprognostic (1.50e-1)" "unprognostic (2.42e-2)" "unprognostic (1.15e-1)" "unprognostic (1.90e-1)" "unprognostic (8.35e-2)" "unprognostic (2.31e-2)" "unprognostic (6.72e-2)" "unprognostic (1.15e-1)" "unprognostic (3.38e-2)" "unprognostic (8.93e-2)" "unprognostic (1.24e-2)" "unprognostic (1.85e-1)" "unprognostic (2.17e-1)" "unprognostic (2.11e-2)" "unprognostic (1.59e-2)" "unprognostic (2.40e-2)" "unprognostic (1.17e-1)" "unprognostic (5.29e-2)" "unprognostic (4.38e-3)" "unprognostic (2.08e-2)" "unprognostic (1.67e-1)" "unprognostic (4.51e-2)" "potential prognostic favorable (7.75e-6)" "unprognostic (2.99e-1)" "unprognostic (1.29e-1)" "unprognostic (1.29e-1)" "unprognostic (1.69e-2)" "unprognostic (6.58e-2)" KALRN "ARHGEF24, DUET, duo, HAPIP, Hs.8004, Kalirin, TRAD" ENSG00000160145 "Kalirin RhoGEF kinase" O60229 3 124033369-124726325 "Cancer-related genes, Enzymes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 972.0;Brain inhibitory neurons: 697.8;Gonadotrophs: 812.9;Lymphatic endothelial cells: 1324.3;Peritubular myoid cells: 539.3;Vascular endothelial cells: 529.1;Vascular smooth muscle cells: 542.4" "Cell type enhanced" "Detected in many" "Endothelial cells: 1324.3;Neuronal cells: 972.0;Pituitary endocrine cells: 812.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.7" "Lineage enriched" "Detected in single" 6 "T-cells: 1.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 8923991.1" "Low tissue specificity" "Detected in many" "HPA011913, CAB026456" Approved Approved Nucleoplasm,Cytosol NA NA 45000 "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Nucleoplasm, Cytosol" "CAB026456: , HPA011913: " "unprognostic (2.11e-1)" "unprognostic (1.94e-2)" "unprognostic (1.88e-1)" "unprognostic (7.86e-2)" "unprognostic (9.66e-2)" "unprognostic (9.37e-2)" "unprognostic (1.85e-1)" "unprognostic (5.12e-2)" "unprognostic (1.96e-1)" "unprognostic (3.03e-2)" "potential prognostic favorable (2.92e-7)" "unprognostic (2.86e-2)" "unprognostic (1.54e-1)" "unprognostic (2.66e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (7.13e-2)" "unprognostic (1.21e-2)" "unprognostic (7.97e-2)" "unprognostic (1.35e-1)" "unprognostic (2.30e-2)" "unprognostic (1.98e-1)" "unprognostic (4.27e-3)" "unprognostic (1.63e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "unprognostic (4.43e-2)" "unprognostic (9.62e-2)" "unprognostic (2.46e-1)" "unprognostic (2.54e-3)" "unprognostic (2.19e-1)" KANSL1 "CENP-36, DKFZP727C091, KIAA1267, MSL1v1, NSL1" ENSG00000120071 "KAT8 regulatory NSL complex subunit 1" Q7Z3B3 17 46029916-46225389 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 466.3;Bergmann glia: 542.1;Brain excitatory neurons: 455.9;Brain inhibitory neurons: 448.5;Choroid plexus epithelial cells: 976.6;Distal convoluted tubule cells: 550.0;Ependymal cells: 642.6;Loop of henle epithelial cells: 515.3;Microglia: 790.8;Oligodendrocyte progenitor cells: 621.2;Oligodendrocytes: 660.0;Other brain neurons: 352.0;Papillary tip epithelial cells: 449.6;Podocytes: 417.1;Proximal tubule cells: 463.7;Renal collecting duct intercalated cells: 509.4;Renal collecting duct principal cells: 519.6;Renal connecting tubule cells: 515.6" "Group enriched" "Detected in many" 4 "Ciliated cells: 976.6;Ductal cells: 519.6;Glial cells: 790.8;Neuronal cells: 455.9;Renal nephron cells: 550.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 155825.3;T-cells: 163307.4" "Tissue enriched" "Detected in single" 6338 "lymphoid tissue: 633783.4" "HPA006874, HPA007208" Approved Supported Nucleoplasm No No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 102: Non-specific - Mixed function" 51 Nucleoplasm "HPA006874: , HPA007208: " "unprognostic (8.93e-2)" "unprognostic (2.77e-1)" "unprognostic (2.69e-1)" "unprognostic (5.99e-2)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (8.55e-2)" "unprognostic (9.72e-2)" "unprognostic (9.23e-2)" "unprognostic (2.64e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (3.17e-2)" "unprognostic (4.95e-2)" "unprognostic (6.45e-2)" "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (4.29e-2)" "unprognostic (3.19e-2)" "unprognostic (1.76e-1)" "unprognostic (4.78e-3)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (5.22e-2)" "unprognostic (1.79e-2)" "unprognostic (2.21e-2)" "unprognostic (3.20e-2)" "unprognostic (2.49e-1)" "unprognostic (3.99e-2)" "unprognostic (2.23e-2)" "unprognostic (2.95e-2)" KANSL3 "FLJ10081, KIAA1310, NSL3, Rcd1" ENSG00000114982 "KAT8 regulatory NSL complex subunit 3" Q9P2N6 2 96593170-96642787 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 182.1" "Cell type enhanced" "Detected in all" "Myocytes: 182.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 10952581.2" "Tissue enriched" "Detected in single" 11246 "lymphoid tissue: 1124553.5" "HPA035017, HPA035018" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 Nucleoplasm Vesicles "HPA035017: , HPA035018: " "unprognostic (1.36e-1)" "unprognostic (7.38e-3)" "unprognostic (7.29e-2)" "unprognostic (8.64e-2)" "unprognostic (1.33e-2)" "unprognostic (3.25e-1)" "unprognostic (6.25e-2)" "unprognostic (1.29e-3)" "unprognostic (3.06e-3)" "potential prognostic favorable (2.32e-6)" "unprognostic (1.38e-2)" "unprognostic (1.22e-1)" "unprognostic (2.57e-1)" "unprognostic (4.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.00e-1)" "potential prognostic favorable (8.99e-4)" "unprognostic (7.73e-2)" "unprognostic (1.94e-1)" "unprognostic (9.25e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (7.41e-2)" "unprognostic (3.08e-1)" "unprognostic (3.34e-1)" "unprognostic (2.58e-1)" "unprognostic (3.03e-2)" "unprognostic (1.53e-1)" "unprognostic (6.64e-3)" "unprognostic (1.06e-2)" KARS1 "DFNB89, KARS, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase 1" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Intellectual disability, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 269.0;Late primary spermatocytes: 281.3;Late spermatids: 394.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 394.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" Enzyme NA NA 74000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 46 Cytosol "Plasma membrane" "HPA041345: , HPA041550: " "unprognostic (1.23e-3)" "unprognostic (5.25e-2)" "unprognostic (9.31e-2)" "unprognostic (1.63e-1)" "unprognostic (1.99e-1)" "unprognostic (4.85e-2)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (1.54e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (9.69e-2)" "unprognostic (1.48e-1)" "unprognostic (8.27e-3)" "potential prognostic unfavorable (6.35e-5)" "unprognostic (5.33e-3)" "unprognostic (1.74e-1)" "unprognostic (2.69e-1)" "unprognostic (2.02e-1)" "unprognostic (2.24e-2)" "unprognostic (3.75e-3)" "unprognostic (1.43e-1)" "unprognostic (3.36e-2)" "unprognostic (5.11e-2)" "unprognostic (3.80e-1)" "unprognostic (1.67e-1)" "unprognostic (1.05e-1)" "unprognostic (9.64e-2)" "unprognostic (2.63e-1)" "unprognostic (4.42e-2)" KAT2B "GCN5, GCN5L, P/CAF, PCAF" ENSG00000114166 "Lysine acetyltransferase 2B" Q92831 3 20040446-20154404 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 451.1;Oligodendrocyte progenitor cells: 760.0;Oligodendrocytes: 331.8;Pituicytes/FSCs: 663.0" "Cell type enhanced" "Detected in many" "Glial cells: 760.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 887.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "skin cancer: 35.4" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 305806.9;Neutrophils: 312470.5" "Tissue enriched" "Detected in single" 935 "lymphoid tissue: 93524.9" "HPA002470, CAB004526, HPA055839, HPA073897" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 144 Nucleoplasm Cytosol "CAB004526: , HPA002470: , HPA055839: , HPA073897: " "unprognostic (4.17e-2)" "unprognostic (2.80e-2)" "unprognostic (9.93e-3)" "unprognostic (1.37e-1)" "unprognostic (2.77e-1)" "unprognostic (1.52e-1)" "unprognostic (2.91e-2)" "unprognostic (8.25e-2)" "unprognostic (1.21e-2)" "unprognostic (2.67e-2)" "potential prognostic favorable (8.72e-7)" "unprognostic (3.88e-2)" "unprognostic (1.07e-1)" "unprognostic (3.61e-1)" "potential prognostic favorable (1.84e-4)" "potential prognostic favorable (8.66e-4)" "unprognostic (2.63e-1)" "unprognostic (8.12e-2)" "unprognostic (7.31e-2)" "unprognostic (1.70e-1)" "unprognostic (4.25e-1)" "unprognostic (2.01e-2)" "unprognostic (9.52e-2)" "unprognostic (1.22e-1)" "unprognostic (1.55e-1)" "unprognostic (2.47e-1)" "unprognostic (7.58e-2)" "unprognostic (3.61e-2)" "unprognostic (1.92e-1)" "unprognostic (9.87e-2)" "unprognostic (3.20e-1)" KAT5 "cPLA2, ESA1, HTATIP, HTATIP1, PLIP, TIP60, ZC2HC5" ENSG00000172977 "Lysine acetyltransferase 5" Q92993 11 65711996-65719604 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "DNA damage, DNA repair, Growth regulation, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 152.5" "Cell type enhanced" "Detected in all" "Trophoblast cells: 152.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Keratinocytes: 1658112.4" "Group enriched" "Detected in many" "intestine: 840082.6;lymphoid tissue: 443564.5;ovary: 503745.2" "HPA016953, HPA074328" Approved Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 288 Nucleoplasm "Vesicles, Cytosol" "HPA016953: , HPA074328: " "unprognostic (3.47e-1)" "unprognostic (2.35e-1)" "unprognostic (1.45e-2)" "unprognostic (7.01e-2)" "unprognostic (1.10e-1)" "unprognostic (4.54e-1)" "unprognostic (1.34e-1)" "unprognostic (1.99e-1)" "unprognostic (1.06e-1)" "unprognostic (3.34e-1)" "validated prognostic favorable (4.81e-10)" "validated prognostic favorable (7.57e-5)" "potential prognostic favorable (2.19e-5)" "unprognostic (6.92e-3)" "unprognostic (3.79e-1)" "unprognostic (4.68e-3)" "unprognostic (7.04e-3)" "unprognostic (4.27e-1)" "unprognostic (2.18e-1)" "unprognostic (2.72e-1)" "unprognostic (3.65e-1)" "unprognostic (2.86e-1)" "unprognostic (1.01e-1)" "unprognostic (2.38e-1)" "unprognostic (1.03e-1)" "unprognostic (5.61e-2)" "unprognostic (3.21e-1)" "unprognostic (2.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" KATNA1 ENSG00000186625 "Katanin catalytic subunit A1" O75449 6 149594873-149648972 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 462.8;Late primary spermatocytes: 275.1;Late spermatids: 278.4" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 462.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 406916.4" "Group enriched" "Detected in many" "bone marrow: 880885.2;lymphoid tissue: 398717.7;salivary gland: 239674.1" HPA036207 Approved Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 18 "Centriolar satellite" Nucleoplasm "HPA036207: " "unprognostic (7.00e-2)" "unprognostic (5.03e-2)" "unprognostic (3.86e-2)" "unprognostic (9.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.59e-1)" "unprognostic (5.75e-2)" "unprognostic (1.67e-2)" "unprognostic (6.54e-2)" "unprognostic (3.81e-2)" "potential prognostic favorable (1.93e-6)" "unprognostic (5.49e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (8.88e-8)" "unprognostic (1.83e-3)" "unprognostic (7.60e-2)" "unprognostic (2.38e-1)" "unprognostic (1.59e-2)" "unprognostic (3.92e-2)" "unprognostic (7.48e-3)" "unprognostic (6.07e-2)" "unprognostic (1.38e-1)" "unprognostic (1.49e-2)" "unprognostic (2.92e-1)" "unprognostic (5.78e-3)" "unprognostic (1.51e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-1)" "unprognostic (8.66e-2)" "unprognostic (2.16e-2)" "unprognostic (2.51e-1)" KATNAL1 MGC2599 ENSG00000102781 "Katanin catalytic subunit A1 like 1" Q9BW62 13 30202630-30307551 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 220.3;Ependymal cells: 152.5;Late primary spermatocytes: 155.6" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 220.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 2004383.1;Fallopian tube cells: 853639.0;Microglia and Neuropil: 1901196.3;Neurons: 2076202.6" "Tissue enriched" "Detected in many" "cerebral cortex: 4109700.0" HPA039759 Supported "Mitotic spindle,Centrosome,Mitochondria,Cytosol" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 21 "Centrosome, Cytosol" "Mitotic spindle, Mitochondria" "HPA039759: " "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (2.73e-1)" "unprognostic (3.43e-3)" "unprognostic (9.14e-2)" "potential prognostic unfavorable (2.66e-4)" "unprognostic (1.43e-1)" "unprognostic (1.69e-1)" "unprognostic (5.75e-2)" "unprognostic (3.19e-3)" "potential prognostic favorable (1.23e-6)" "unprognostic (6.86e-3)" "unprognostic (3.00e-1)" "unprognostic (6.90e-3)" "unprognostic (1.46e-1)" "unprognostic (1.55e-1)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (3.45e-3)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (4.00e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-2)" "unprognostic (1.04e-1)" "unprognostic (3.22e-1)" "unprognostic (2.51e-3)" "unprognostic (1.33e-1)" "unprognostic (2.49e-1)" "unprognostic (5.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.42e-1)" KATNAL2 "DKFZP667C165, MGC33211" ENSG00000167216 "Katanin catalytic subunit A1 like 2" Q8IYT4 18 46917492-47103478 "Enzymes, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 11.7;testis: 12.2" "Cell type enhanced" "Detected in many" "Astrocytes: 129.0;Choroid plexus epithelial cells: 298.5;Distal convoluted tubule cells: 114.0;Ependymal cells: 254.7;Late primary spermatocytes: 163.7;Loop of henle epithelial cells: 114.8;Renal connecting tubule cells: 133.4;Respiratory ciliated cells: 126.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 298.5;Spermatogenic cell types: 163.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 271.6;ependymal cell: 257.8" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 17713018.8;Hepatocytes: 20970697.3;Large ducts: 20005245.0;Pancreas epithelial cells: 41112325.8;T-cells: 15799162.9" "Tissue enhanced" "Detected in some" "lymphoid tissue: 16071293.9" "HPA040712, HPA042029" Approved Supported "Nucleoplasm,Intermediate filaments" No No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 3 "Intermediate filaments" Nucleoplasm "HPA040712: , HPA042029: " "unprognostic (1.27e-1)" "unprognostic (1.53e-1)" "unprognostic (2.80e-2)" "unprognostic (1.26e-1)" "unprognostic (4.26e-2)" "unprognostic (2.25e-1)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (2.95e-4)" "unprognostic (9.82e-3)" "unprognostic (6.02e-2)" "unprognostic (2.56e-1)" "potential prognostic favorable (4.45e-4)" "potential prognostic favorable (9.95e-8)" "unprognostic (5.52e-3)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (2.72e-2)" "unprognostic (1.76e-3)" "unprognostic (6.64e-2)" "unprognostic (2.81e-2)" "unprognostic (1.49e-1)" "unprognostic (1.61e-2)" "unprognostic (1.48e-3)" "unprognostic (3.26e-1)" "unprognostic (3.14e-1)" "unprognostic (1.40e-2)" "unprognostic (1.26e-3)" "unprognostic (7.32e-3)" "unprognostic (3.65e-1)" "unprognostic (1.54e-2)" "unprognostic (4.90e-3)" "unprognostic (3.49e-2)" KATNBL1 "C15orf29, FLJ22557" ENSG00000134152 "Katanin regulatory subunit B1 like 1" Q9H079 15 34140674-34210096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1325.5;Neutrophils: 1075.4;Syncytiotrophoblasts: 424.4" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1325.5;Neutrophils: 1075.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 127.9" "Lineage enriched" "Detected in all" 4 "granulocytes: 127.9" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Macrophages: 259005.6;Oocytes: 156455.9" "Not detected" "Not detected" HPA062573 Approved Supported "Nucleoplasm,Midbody,Cleavage furrow,Mitotic spindle" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 39 "Midbody, Mitotic spindle" "Nucleoplasm, Cleavage furrow" "HPA062573: " "unprognostic (3.20e-1)" "unprognostic (1.10e-1)" "unprognostic (7.85e-2)" "unprognostic (7.31e-2)" "potential prognostic favorable (6.92e-4)" "unprognostic (2.67e-2)" "unprognostic (2.14e-3)" "unprognostic (2.00e-2)" "unprognostic (1.81e-3)" "unprognostic (4.72e-2)" "unprognostic (2.61e-1)" "unprognostic (3.69e-1)" "unprognostic (9.64e-2)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (1.59e-1)" "unprognostic (1.91e-1)" "unprognostic (9.58e-3)" "unprognostic (1.03e-1)" "unprognostic (9.30e-3)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (3.81e-5)" "unprognostic (7.37e-2)" "unprognostic (8.11e-3)" "unprognostic (1.11e-1)" "unprognostic (3.65e-3)" "unprognostic (7.10e-2)" "unprognostic (3.28e-2)" "unprognostic (2.23e-2)" "unprognostic (1.95e-1)" KATNIP "JBTS26, KIAA0556" ENSG00000047578 "Katanin interacting protein" O60303 16 27550133-27780344 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 260.1;Cone photoreceptor cells: 225.6;Endometrial ciliated cells: 224.7;Fallopian tube ciliated cells: 217.5;Respiratory ciliated cells: 336.6" "Cell type enhanced" "Detected in all" "Ciliated cells: 336.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 14.3;eosinophil: 3.6;neutrophil: 10.0;NK-cell: 5.0" "Group enriched" "Detected in all" 5 "granulocytes: 14.3;NK-cells: 5.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 2233714.0" "Tissue enriched" "Detected in single" 21796 "fallopian tube: 2179575.3" "HPA035089, HPA035090" Enhanced Approved "Nucleoplasm,Primary cilium,Centriolar satellite,Basal body" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 1: Neuronal - Visual perception" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 "Nucleoplasm, Basal body" "Primary cilium, Centriolar satellite" "HPA035089: , HPA035090: " "unprognostic (9.64e-2)" "unprognostic (2.34e-1)" "unprognostic (2.17e-3)" "unprognostic (1.19e-1)" "unprognostic (2.97e-1)" "unprognostic (1.15e-1)" "unprognostic (1.44e-1)" "unprognostic (8.25e-3)" "potential prognostic unfavorable (5.69e-4)" "unprognostic (1.19e-2)" "unprognostic (2.83e-1)" "unprognostic (1.14e-2)" "unprognostic (6.34e-3)" "unprognostic (4.23e-2)" "unprognostic (7.67e-3)" "unprognostic (1.35e-1)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" "unprognostic (3.56e-1)" "unprognostic (1.11e-1)" "unprognostic (6.79e-3)" "unprognostic (2.02e-1)" "unprognostic (1.83e-2)" "unprognostic (1.06e-2)" "unprognostic (4.19e-2)" "unprognostic (2.49e-1)" "unprognostic (2.35e-1)" "unprognostic (5.52e-3)" "unprognostic (9.39e-3)" KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;lymphoid tissue: 2.2;retina: 4.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 338.9;Cone photoreceptor cells: 5059.4;Corticotrophs: 1310.8;Gonadotrophs: 593.3;Neuroendocrine cells: 864.1;Other brain neurons: 383.4;Pancreatic islet cells: 560.3;Pituitary stem cells: 793.2;Retinal amacrine cells: 469.4;Somatotrophs: 481.7;Thyrotrophs: 359.1" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 864.1;Neuronal cells: 5059.4;Pituitary endocrine cells: 1310.8;Stem cells: 793.2" "Cell type enhanced" "Detected in all" "miscellaneous: 1482.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 2.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 150 "cerebral cortex: 15022.4" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 2 "Plasma membrane" "Nucleoli, Midbody" "HPA065970: " "unprognostic (3.13e-2)" KCND1 Kv4.1 ENSG00000102057 "Potassium voltage-gated channel subfamily D member 1" Q9NSA2 X 48961378-48971844 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in some" "Fibroblasts: 2.4;Hepatic stellate cells: 6.5;Neutrophil progenitors: 2.7;Neutrophils: 3.0;pDCs: 2.6;Peritubular myoid cells: 3.9" "Cell type enhanced" "Detected in some" "Stellate cells: 6.5;Stromal cells: 3.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000524, HPA001066" Supported Uncertain Nucleoplasm Yes No "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "HPA000524: , HPA001066: " "unprognostic (2.38e-2)" "unprognostic (1.78e-1)" "unprognostic (3.50e-1)" "unprognostic (1.10e-1)" "unprognostic (2.20e-2)" "unprognostic (1.67e-1)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (1.64e-2)" "unprognostic (9.18e-3)" "unprognostic (6.29e-3)" "unprognostic (1.23e-1)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (1.48e-1)" "potential prognostic favorable (3.21e-5)" "unprognostic (8.48e-3)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (1.00e-1)" "unprognostic (4.37e-2)" "unprognostic (6.83e-2)" "unprognostic (3.44e-2)" KCNF1 "IK8, KCNF, kH1, Kv5.1" ENSG00000162975 "Potassium voltage-gated channel modifier subfamily F member 1" Q9H3M0 2 10911934-10914225 "Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 28 "brain: 45.3;choroid plexus: 23.5" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 7.8;Brain inhibitory neurons: 10.7;Choroid plexus epithelial cells: 17.0;Extravillous trophoblasts: 22.9;Fallopian secretory cells: 5.1;Late spermatids: 5.8;Oligodendrocyte progenitor cells: 31.4;Other brain neurons: 7.7;Schwann cells: 4.9;Syncytiotrophoblasts: 10.4" "Cell type enhanced" "Detected in some" "Ciliated cells: 17.0;Glial cells: 31.4;Neuronal cells: 10.7;Trophoblast cells: 22.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 46.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 11.5;lung cancer: 9.0" "Breast - Breast glandular cells (progenitors), Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 13085 "lung: 1308536.6" "HPA014738, HPA062278" Enhanced Approved "Nucleoplasm,Golgi apparatus,Vesicles,Primary cilium transition zone" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 35: Neurons - Synaptic function & neurogenesis" 9 "Golgi apparatus" "Nucleoplasm, Vesicles, Primary cilium transition zone" "HPA014738: , HPA062278: " "unprognostic (1.30e-1)" "unprognostic (1.26e-1)" "unprognostic (2.13e-1)" "unprognostic (9.72e-2)" "unprognostic (6.57e-2)" "potential prognostic favorable (9.92e-4)" "unprognostic (6.80e-2)" "unprognostic (1.11e-1)" "unprognostic (5.33e-2)" "unprognostic (8.49e-2)" "unprognostic (3.43e-3)" "unprognostic (1.29e-1)" KCNH5 "eag2, H-EAG2, hEAG2, Kv10.2" ENSG00000140015 "Potassium voltage-gated channel subfamily H member 5" Q8NCM2 14 62699464-63102037 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;retina: 4.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Brain excitatory neurons: 89.8;Brain inhibitory neurons: 87.8;Choroid plexus epithelial cells: 357.0;Corticotrophs: 416.1;Mesothelial cells: 111.8;Oligodendrocyte progenitor cells: 119.3;Other brain neurons: 90.6;Pituitary stem cells: 95.2;Retinal amacrine cells: 498.5;Retinal bipolar cells: 417.9;Retinal pigment epithelial cells: 439.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 357.0;Neuronal cells: 498.5;Pigment cells: 439.1;Pituitary endocrine cells: 416.1" "Cell type enhanced" "Detected in all" "thalamic excitatory: 525.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 1.4;cervical cancer: 1.2" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030487, HPA072351" Uncertain Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 1 Centrosome "Nucleoplasm, Cytosol" "HPA030487: , HPA072351: " "unprognostic (1.56e-1)" KCNJ12 "hIRK1, IRK2, KCNJN1, Kir2.2, Kir2.2v" ENSG00000184185 "Potassium inwardly rectifying channel subfamily J member 12" Q14500 17 21376357-21419870 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 41.8;skeletal muscle: 64.7;tongue: 24.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 19.2;Conjunctival goblet cells: 29.1;Endometrial secretory cells: 31.8;Müller glia: 13.3;Myonuclei: 15.3;Respiratory ionocytes: 15.2;Retinal amacrine cells: 15.4;Retinal horizontal cells: 74.1;Salivary ionocytes: 13.0" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 31.9;Goblet cells: 29.1;Neuronal cells: 74.1;Secretory cells: 31.8" "Cell type enhanced" "Detected in many" "upper rhombic lip: 44.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 58.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA027021 Approved Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 13 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: " "unprognostic (1.01e-3)" "unprognostic (2.04e-1)" "unprognostic (3.70e-2)" "unprognostic (5.14e-3)" "unprognostic (4.92e-2)" "unprognostic (1.56e-1)" "unprognostic (2.78e-3)" "unprognostic (1.35e-1)" "unprognostic (4.27e-2)" "unprognostic (9.21e-2)" KCNJ13 "Kir1.4, Kir7.1, LCA16" ENSG00000115474 "Potassium inwardly rectifying channel subfamily J member 13" O60928 2 232765802-232776565 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Cataract, Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 165.9;intestine: 85.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 62.9;Choroid plexus epithelial cells: 154.5;Enteric transient amplifying cells: 36.9;Enterocytes: 119.0;Epicardial cells: 79.6;Melanocytes: 38.6;Retinal pigment epithelial cells: 68.2" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 79.6;Ciliated cells: 154.5;Enterocytes: 119.0;Myocytes: 62.9;Pigment cells: 68.2" "Cell type enriched" "Detected in all" 31 "choroid plexus epithelial cell: 238.7" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 4.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.8;Skin Cutaneous Melanoma (TCGA): 12.0" "Region enriched" "Detected in all" 15 "choroid plexus: 342.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Kidney cancer: 1.1" "Kidney - Ascending Loop of Henle cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 851 "intestine: 85067.5" HPA051609 Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Nuclear membrane" "Plasma membrane" "HPA051609: " "unprognostic (1.97e-2)" "unprognostic (3.23e-2)" "unprognostic (2.59e-1)" "unprognostic (8.71e-2)" "unprognostic (4.82e-2)" "unprognostic (2.75e-3)" "unprognostic (6.18e-3)" "unprognostic (2.20e-2)" KCNJ18 "KIR2.6, TTPP2" ENSG00000260458 "Potassium inwardly rectifying channel subfamily J member 18" B7U540 17 21692523-21704612 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 7.3" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 1.9;Suprabasal keratinocytes: 1.4" "Cell type enhanced" "Detected in some" "Goblet cells: 1.9;Suprabasal cells: 1.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027021 Uncertain Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 7: Liver cancer - Metabolism" "Cluster 26: Keratinocytes - Keratinization" 3 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA027021: " "unprognostic (2.36e-1)" KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 578.5;Brain inhibitory neurons: 266.8;Choroid plexus epithelial cells: 560.5;Corticotrophs: 996.3;Ependymal cells: 262.3;Lactotrophs: 642.9;Pituicytes/FSCs: 355.3;Renal collecting duct intercalated cells: 328.1;Renal collecting duct principal cells: 237.3;Renal connecting tubule cells: 337.7;Retinal amacrine cells: 271.3;Retinal horizontal cells: 565.0;Somatotrophs: 401.4;Thyrotrophs: 723.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 560.5;Ductal cells: 337.7;Glial cells: 355.3;Neuronal cells: 578.5;Pituitary endocrine cells: 996.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 21.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 2.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Kidney - Ascending Loop of Henle cells, Liver - Hepatocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5803 "Astrocytes and Neuropil: 299238.0;Microglia and Neuropil: 737215.2;Neurons: 704369.2" "Tissue enriched" "Detected in single" 6076 "cerebral cortex: 607570.7" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Mitochondria "Plasma membrane" "HPA024231: , HPA064138: " "unprognostic (1.63e-1)" "unprognostic (2.04e-1)" "unprognostic (7.17e-2)" "unprognostic (1.54e-2)" "unprognostic (8.51e-2)" "unprognostic (3.52e-2)" "unprognostic (2.23e-1)" "potential prognostic favorable (8.20e-9)" "unprognostic (9.44e-3)" "unprognostic (5.39e-2)" "unprognostic (1.18e-1)" "unprognostic (1.42e-1)" "unprognostic (9.15e-2)" "unprognostic (1.02e-2)" "unprognostic (3.22e-1)" "unprognostic (2.83e-1)" "unprognostic (4.09e-2)" "unprognostic (1.27e-3)" "unprognostic (2.30e-1)" "unprognostic (1.04e-1)" KCNK17 "K2p17.1, TALK-2, TALK2, TASK-4, TASK4" ENSG00000124780 "Potassium two pore domain channel subfamily K member 17" Q96T54 6 39299001-39314461 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 26.6" "Cell type enhanced" "Detected in some" "Epididymal efferent duct absorptive cells: 10.3;Fibroblasts: 6.5;Hepatic stellate cells: 19.4;Innate lymphoid cells: 7.0;Pancreatic islet cells: 38.2;pDCs: 33.2;Pericytes: 19.6;Thymocytes: 46.6;Vascular smooth muscle cells: 6.7" "Cell type enhanced" "Detected in many" "dendritic cells: 33.2;Mural cells: 19.6;Pancreatic islet cells: 38.2;Stellate cells: 19.4;T-cells: 46.6" "Cell type enriched" "Detected in some" 21 "fibroblast: 115.2" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 4.2" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 63.9" "Lineage enriched" "Detected in many" 34 "dendritic cells: 63.9" "Cancer enhanced" "Detected in some" "Leukemia: 5.6;thyroid cancer: 3.4" "Colon - Colon enteroendocrine cells" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5102 "Pancreatic islets: 510197.1" "Not detected" "Not detected" HPA043892 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 110: Mural cells - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA043892: " "unprognostic (1.22e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (2.30e-2)" "potential prognostic favorable (4.33e-4)" "potential prognostic favorable (4.67e-5)" "unprognostic (2.58e-1)" "unprognostic (2.76e-2)" "unprognostic (2.08e-2)" "unprognostic (8.90e-3)" "unprognostic (7.89e-2)" "unprognostic (3.70e-2)" "unprognostic (2.14e-1)" "unprognostic (1.35e-1)" KCNN1 "hSK1, KCa2.1" ENSG00000105642 "Potassium calcium-activated channel subfamily N member 1" Q92952 19 17951293-18000085 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "brain: 23.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 12.4;Brain inhibitory neurons: 6.8;cDC: 8.8;Differentiating spermatogonia: 10.6;Endometrial glandular cells: 7.9;Retinal ganglion cells: 15.5;Undifferentiated spermatogonia: 14.2" "Cell type enhanced" "Detected in many" "Neuronal cells: 15.5;Spermatogenic cell types: 14.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 16.2" "Breast - Breast glandular cells, Colon - Enteric glia cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA065938 Approved "Actin filaments,Cytosol" Yes No "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Actin filaments, Cytosol" "HPA065938: " "unprognostic (7.84e-2)" "unprognostic (2.36e-1)" "unprognostic (4.00e-1)" "unprognostic (1.00e-2)" "unprognostic (6.57e-3)" "unprognostic (7.98e-2)" "unprognostic (2.80e-1)" "unprognostic (2.47e-1)" "unprognostic (1.62e-1)" "unprognostic (2.95e-1)" KCNRG ENSG00000198553 "Potassium channel regulator" Q8N5I3 13 50015254-50020922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "fallopian tube: 33.6" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 51.8;Epicardial cells: 18.2;Epididymal efferent duct ciliated cells: 30.6;Fallopian tube ciliated cells: 110.8;Late primary spermatocytes: 29.0;Late spermatids: 20.3;Respiratory ciliated cells: 99.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 18.2;Ciliated cells: 110.8;Spermatogenic cell types: 29.0" "Cell type enriched" "Detected in single" 6 "ependymal cell: 6.2" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 34296 "Fallopian tube cells: 3429631.6" "Tissue enriched" "Detected in single" 9259 "fallopian tube: 925900.1" HPA001027 Uncertain "Golgi apparatus,Vesicles,Basal body" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 6: Non-specific - Immune response" "Cluster 60: Prostate cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 2 "Golgi apparatus, Vesicles" "Basal body" "HPA001027: " "unprognostic (2.12e-1)" "unprognostic (3.18e-1)" "unprognostic (2.26e-1)" "unprognostic (1.04e-1)" "unprognostic (5.53e-3)" "unprognostic (2.13e-2)" "unprognostic (2.54e-1)" "unprognostic (4.49e-2)" "unprognostic (1.63e-2)" "unprognostic (1.20e-2)" "unprognostic (2.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.85e-1)" KCNU1 "KCa5.1, Kcnma3, KCNMC1, Slo3" ENSG00000215262 "Potassium calcium-activated channel subfamily U member 1" A8MYU2 8 36784324-36936125 "Human disease related genes, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 18 "testis: 6.5" "Group enriched" "Detected in some" 9 "Adipocytes: 106.5;Early spermatids: 112.2;Late primary spermatocytes: 65.2;Late spermatids: 32.0" "Group enriched" "Detected in some" 12 "Adipocytes: 106.5;Spermatogenic cell types: 112.2" "Cell type enhanced" "Detected in some" "astrocyte: 5.1;choroid plexus epithelial cell: 4.5" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA063317 Approved "Plasma membrane,Principal piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 7: Liver cancer - Metabolism" "Cluster 89: Adipocytes - Lipid metabolism" "Plasma membrane, Principal piece" "HPA063317: " "unprognostic (2.99e-2)" "unprognostic (4.25e-2)" "unprognostic (1.62e-2)" KCTD1 C18orf5 ENSG00000134504 "Potassium channel tetramerization domain containing 1" Q719H9 18 26454910-26657401 "Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 559.6;Ependymal cells: 301.5;Loop of henle epithelial cells: 309.6;Pituicytes/FSCs: 494.4;Pituitary stem cells: 322.6" "Cell type enhanced" "Detected in many" "Glial cells: 494.4;Renal nephron cells: 559.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 981738.4;Neurons: 665273.6" "Low tissue specificity" "Detected in many" "HPA057808, HPA062486" Approved "Nucleoplasm,Nucleoli,Cytokinetic bridge,Centriolar satellite" Yes NA "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 23 Nucleoplasm "Nucleoli, Cytokinetic bridge, Centriolar satellite" "HPA057808: , HPA062486: " "unprognostic (1.14e-2)" "unprognostic (5.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (9.82e-2)" "unprognostic (5.39e-3)" "unprognostic (1.66e-2)" "unprognostic (1.40e-1)" "unprognostic (2.39e-1)" "unprognostic (9.69e-2)" "unprognostic (1.65e-3)" "potential prognostic favorable (6.32e-4)" "unprognostic (3.25e-3)" "unprognostic (1.13e-1)" "unprognostic (1.16e-3)" "unprognostic (2.85e-1)" "unprognostic (8.69e-3)" "unprognostic (4.64e-3)" "unprognostic (1.86e-2)" "unprognostic (2.67e-1)" "unprognostic (1.18e-2)" "unprognostic (1.57e-1)" "unprognostic (1.08e-1)" "unprognostic (5.44e-2)" "unprognostic (2.74e-2)" "unprognostic (1.57e-1)" "unprognostic (2.53e-2)" "unprognostic (1.24e-2)" "unprognostic (1.00e-1)" "unprognostic (9.50e-2)" KCTD13 "FKSG86, PDIP1, POLDIP1" ENSG00000174943 "Potassium channel tetramerization domain containing 13" Q8WZ19 16 29905012-29926236 "Disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Autism, Autism spectrum disorder, Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 64.5;testis: 61.7" "Group enriched" "Detected in many" 4 "Epicardial cells: 270.6;Sertoli cells: 133.9" "Group enriched" "Detected in all" 4 "Barrier epithelial cells: 270.6;Reproductive supporting cells: 133.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 252 "Neurons: 25169.4" "Not detected" "Not detected" HPA043524 Enhanced Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 43 "Nucleoplasm, Nuclear bodies" "HPA043524: " "unprognostic (1.32e-1)" "unprognostic (6.30e-3)" "unprognostic (2.02e-2)" "potential prognostic favorable (2.34e-5)" "unprognostic (1.34e-1)" "unprognostic (1.25e-1)" "unprognostic (2.77e-1)" "unprognostic (2.06e-3)" "unprognostic (1.36e-1)" "unprognostic (1.41e-2)" "unprognostic (2.30e-2)" "unprognostic (4.32e-2)" "unprognostic (5.37e-3)" "unprognostic (8.89e-2)" "unprognostic (3.12e-2)" "unprognostic (6.70e-2)" "unprognostic (2.20e-1)" "unprognostic (3.58e-2)" "unprognostic (1.98e-1)" "unprognostic (2.71e-2)" "unprognostic (4.49e-2)" "unprognostic (2.43e-2)" "unprognostic (5.37e-3)" "unprognostic (1.86e-2)" "unprognostic (3.07e-1)" "unprognostic (6.15e-2)" "unprognostic (3.09e-3)" "unprognostic (2.26e-1)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (2.92e-2)" KCTD9 "BTBD27, FLJ20038" ENSG00000104756 "Potassium channel tetramerization domain containing 9" Q7L273 8 25427847-25458476 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 159.8;Innate lymphoid cells: 164.9" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "fibroblast: 210.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 1089042.2;Smooth muscle cells: 1158996.5" "Not detected" "Not detected" "HPA042468, HPA047902" Approved "Nucleoplasm,Intermediate filaments,Cytosol" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 93 Nucleoplasm "Intermediate filaments, Cytosol" "HPA042468: , HPA047902: " "unprognostic (2.11e-2)" "unprognostic (5.00e-2)" "unprognostic (8.88e-2)" "unprognostic (1.87e-1)" "unprognostic (1.70e-3)" "unprognostic (2.14e-1)" "unprognostic (4.63e-2)" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.88e-2)" "validated prognostic favorable (2.37e-5)" "validated prognostic favorable (7.99e-4)" "unprognostic (4.29e-2)" "unprognostic (1.24e-2)" "unprognostic (1.90e-2)" "unprognostic (2.19e-3)" "unprognostic (1.04e-1)" "unprognostic (2.42e-1)" "unprognostic (1.48e-1)" "unprognostic (1.96e-1)" "unprognostic (1.32e-3)" "unprognostic (3.65e-3)" "unprognostic (1.92e-2)" "unprognostic (3.59e-1)" "unprognostic (3.31e-2)" "unprognostic (3.78e-3)" "unprognostic (2.54e-1)" "unprognostic (1.47e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (4.95e-2)" KDELR3 ENSG00000100196 "KDEL endoplasmic reticulum protein retention receptor 3" O43731 22 38468078-38483447 "Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 48.4;Extravillous trophoblasts: 112.6;Gastric chief cells: 56.8;Gastric progenitor cells: 80.7;Goblet cells: 57.5;Hepatic stellate cells: 154.9;Lacrimal acinar cells: 48.0" "Cell type enhanced" "Detected in many" "Stellate cells: 154.9;Trophoblast cells: 112.6" "Cell type enhanced" "Detected in many" "ependymal cell: 6.1;fibroblast: 6.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Pancreas epithelial cells: 2911896.4" "Group enriched" "Detected in some" 2142 "intestine: 294853.8;salivary gland: 133635.4" "HPA043477, HPA076405" Uncertain Supported "Endoplasmic reticulum" No No "Cluster 14: Non-specific - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 16: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 19 "Endoplasmic reticulum" "HPA043477: , HPA076405: " "unprognostic (1.65e-2)" "unprognostic (1.34e-1)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "unprognostic (2.60e-1)" "unprognostic (6.39e-2)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (2.77e-4)" "unprognostic (4.36e-2)" "unprognostic (3.11e-1)" "validated prognostic unfavorable (1.47e-8)" "validated prognostic unfavorable (2.30e-4)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (1.64e-2)" "unprognostic (5.79e-2)" "unprognostic (2.21e-2)" "unprognostic (2.97e-1)" "unprognostic (2.08e-1)" "unprognostic (3.13e-1)" "unprognostic (3.08e-2)" "unprognostic (1.69e-2)" "unprognostic (1.56e-1)" "unprognostic (9.75e-2)" "unprognostic (1.66e-1)" "unprognostic (2.55e-2)" "unprognostic (2.96e-1)" "unprognostic (1.26e-1)" "unprognostic (1.61e-1)" "unprognostic (7.41e-2)" "unprognostic (4.27e-1)" KDM4B "JMJD2B, KIAA0876, TDRD14B" ENSG00000127663 "Lysine demethylase 4B" O94953 19 4969113-5153598 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 748.1" "Cell type enhanced" "Detected in all" "Neutrophils: 748.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 5.1;dendritic cells: 1.7;granulocytes: 4.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 4027205.3" "Tissue enriched" "Detected in single" 49105 "lymphoid tissue: 4910538.2" HPA071568 Supported Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 31 Nucleoplasm Cytosol "HPA071568: " "unprognostic (3.44e-2)" "unprognostic (1.73e-2)" "unprognostic (4.64e-1)" "unprognostic (9.84e-2)" "unprognostic (3.47e-1)" "unprognostic (8.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.25e-2)" "unprognostic (1.08e-3)" "unprognostic (3.18e-2)" "unprognostic (2.81e-3)" "unprognostic (1.97e-1)" "unprognostic (4.25e-2)" "unprognostic (4.64e-2)" "unprognostic (2.61e-1)" "unprognostic (2.77e-1)" "unprognostic (1.56e-1)" "unprognostic (2.44e-1)" "unprognostic (3.55e-2)" "unprognostic (1.05e-1)" "unprognostic (3.98e-1)" "unprognostic (8.04e-3)" "unprognostic (2.93e-3)" "unprognostic (3.46e-2)" "unprognostic (5.23e-2)" "unprognostic (4.30e-2)" "unprognostic (1.47e-2)" "unprognostic (2.26e-1)" "unprognostic (9.04e-2)" "unprognostic (1.68e-2)" "potential prognostic favorable (4.33e-5)" KDM6A UTX ENSG00000147050 "Lysine demethylase 6A" O15550 X 44873188-45112779 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1305.9;Neutrophils: 1251.5" "Cell type enhanced" "Detected in all" "Neutrophils: 1305.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 4014481.3;Neutrophils: 5825735.2" "Tissue enriched" "Detected in single" 2585 "lymphoid tissue: 258540.3" "HPA000568, HPA001165, HPA002111" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA000568: , HPA001165: , HPA002111: " "unprognostic (2.15e-2)" "unprognostic (5.81e-3)" "unprognostic (2.07e-1)" "unprognostic (3.83e-2)" "unprognostic (3.81e-3)" "unprognostic (6.59e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-1)" "unprognostic (7.68e-2)" "unprognostic (4.89e-1)" "unprognostic (1.10e-1)" "unprognostic (6.51e-2)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.14e-1)" "unprognostic (2.98e-2)" "unprognostic (8.95e-2)" "unprognostic (7.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.29e-2)" "unprognostic (3.20e-1)" "unprognostic (1.55e-1)" "unprognostic (1.21e-1)" "unprognostic (3.75e-3)" "unprognostic (1.73e-1)" "unprognostic (7.95e-2)" "unprognostic (2.25e-2)" "unprognostic (1.11e-1)" "unprognostic (1.34e-2)" KDM7A "JHDM1D, KIAA1718" ENSG00000006459 "Lysine demethylase 7A" Q6ZMT4 7 140084746-140176983 "Enzymes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 318.5;Neutrophil progenitors: 425.8;Neutrophils: 627.1" "Cell type enhanced" "Detected in all" "Neutrophils: 627.1" "Cell type enhanced" "Detected in all" "endothelial cell: 263.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA012114 Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 32: Non-specific - Cell proliferation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 Nucleoplasm Nucleoli "HPA012114: " "unprognostic (1.38e-3)" "unprognostic (1.64e-1)" "unprognostic (8.04e-3)" "unprognostic (6.39e-2)" "unprognostic (8.14e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-3)" "unprognostic (6.65e-2)" "unprognostic (7.89e-2)" "validated prognostic favorable (1.44e-5)" "validated prognostic favorable (1.51e-4)" "unprognostic (2.58e-1)" "unprognostic (2.19e-2)" "unprognostic (3.77e-2)" "unprognostic (1.40e-1)" "potential prognostic favorable (2.71e-4)" "unprognostic (1.16e-2)" "unprognostic (5.84e-2)" "unprognostic (3.83e-3)" "unprognostic (1.10e-1)" "unprognostic (2.73e-1)" "unprognostic (1.04e-2)" "unprognostic (2.23e-1)" "unprognostic (1.06e-1)" "unprognostic (1.79e-1)" "unprognostic (1.19e-1)" "unprognostic (8.51e-2)" "unprognostic (3.00e-1)" KDR "CD309, FLK1, VEGFR, VEGFR2" ENSG00000128052 "Kinase insert domain receptor" P35968 4 55078481-55125595 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Lymphatic endothelial cells: 240.8;Mesothelial cells: 191.9;Müller glia: 283.5;Vascular endothelial cells: 240.6" "Group enriched" "Detected in many" 4 "Barrier epithelial cells: 191.9;Endothelial cells: 240.8;Glial cells: 283.5" "Group enriched" "Detected in many" 4 "endothelial cell: 114.8;fibroblast: 55.5" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 27.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 6 "Rhabdoid: 54.8" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Liver - Sinusoid Endothelial cells, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9122 "Glomeruli: 1342129.4;Macrophages: 904831.4;Pancreatic islets: 489654.2" "Tissue enriched" "Detected in single" 30376 "heart muscle: 3037579.7" "CAB004028, HPA069304, HPA073577" Enhanced Approved "Nuclear membrane,Vesicles,Cytosol,Connecting piece,Mid piece,Principal piece" "Intracellular and membrane" Receptor NA NA 2300000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 44 Vesicles "Nuclear membrane, Cytosol, Connecting piece, Mid piece, Principal piece" "CAB004028: , HPA069304: , HPA073577: " "unprognostic (2.09e-2)" "unprognostic (1.63e-1)" "unprognostic (2.24e-1)" "unprognostic (3.63e-1)" "unprognostic (1.95e-1)" "unprognostic (2.04e-1)" "unprognostic (7.05e-2)" "unprognostic (1.31e-2)" "unprognostic (1.09e-1)" "validated prognostic favorable (5.31e-10)" "validated prognostic favorable (1.73e-5)" "unprognostic (3.65e-3)" "unprognostic (1.16e-2)" "unprognostic (1.62e-3)" "unprognostic (8.98e-2)" "unprognostic (2.02e-3)" "unprognostic (5.90e-2)" "unprognostic (1.76e-2)" "unprognostic (3.31e-2)" "unprognostic (2.51e-2)" "unprognostic (4.01e-2)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (7.48e-2)" "unprognostic (1.26e-1)" "unprognostic (5.11e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-2)" "unprognostic (3.72e-1)" "unprognostic (1.09e-3)" KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 53.1;testis: 36.6" "Group enriched" "Detected in some" 4 "Erythrocyte progenitors: 28.6;Oligodendrocytes: 32.9;Sertoli cells: 22.8" "Group enriched" "Detected in some" 4 "Erythrocytes: 28.6;Glial cells: 32.9;Reproductive supporting cells: 22.8" "Cell type enriched" "Detected in many" 5 "oligodendrocyte: 54.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 19 "Leukemia: 10.4" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 10852 "Alveolar cell types: 1396357.2;Glomeruli: 774093.1" "Tissue enhanced" "Detected in many" "pancreas: 2091663.3;skin: 1468707.4" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 80: Oligodendrocytes - Myelination" 8 "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (9.70e-2)" "unprognostic (2.99e-2)" "potential prognostic favorable (2.19e-4)" "unprognostic (1.98e-2)" "unprognostic (1.49e-2)" "unprognostic (1.35e-2)" "unprognostic (4.43e-2)" "unprognostic (5.55e-2)" "unprognostic (1.52e-1)" KHDRBS3 "Etle, etoile, SALP, SLM-2, SLM2, T-STAR" ENSG00000131773 "KH RNA binding domain containing, signal transduction associated 3" O75525 8 135457456-135656722 "Predicted intracellular proteins" "Host-virus interaction, mRNA processing, Transcription, Transcription regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 147.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 347.9;Breast lactating cells: 365.9;Early spermatids: 433.2;Late primary spermatocytes: 548.5;Microglia: 873.7;Oligodendrocyte progenitor cells: 831.5;Retinal bipolar cells: 450.4;Schwann cells: 656.4" "Cell type enhanced" "Detected in many" "Glial cells: 873.7;Neuronal cells: 450.4;Spermatogenic cell types: 548.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 72.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "eosinophil: 1.2" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.2" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Spleen - Fibroblasts_1, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 196259169.5" "Tissue enhanced" "Detected in many" "heart muscle: 16605101.2" "HPA000275, HPA000500, HPA000981" Enhanced Supported Nucleoplasm NA NA "Cluster 67: Testis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 55 Nucleoplasm "HPA000275: , HPA000500: , HPA000981: " "unprognostic (1.02e-1)" "unprognostic (2.19e-1)" "unprognostic (4.49e-2)" "unprognostic (1.59e-1)" "unprognostic (1.94e-1)" "unprognostic (4.38e-3)" "unprognostic (2.94e-1)" "unprognostic (1.11e-3)" "unprognostic (4.06e-1)" "unprognostic (7.00e-3)" "potential prognostic favorable (2.85e-9)" "unprognostic (2.11e-3)" "unprognostic (1.00e-1)" "unprognostic (2.10e-2)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (2.31e-1)" "unprognostic (5.04e-2)" "unprognostic (1.05e-1)" "unprognostic (1.26e-2)" "unprognostic (4.84e-2)" "unprognostic (7.60e-3)" "unprognostic (3.67e-2)" "unprognostic (5.48e-2)" "unprognostic (5.19e-2)" "unprognostic (9.43e-2)" "unprognostic (1.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.30e-1)" "unprognostic (1.38e-1)" "unprognostic (3.09e-1)" "unprognostic (1.42e-1)" KIAA0319 NMIG ENSG00000137261 KIAA0319 Q5VV43 6 24544104-24646191 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 11.2;pituitary gland: 3.9" "Cell type enhanced" "Detected in many" "Astrocytes: 190.9;Brain excitatory neurons: 157.5;Brain inhibitory neurons: 102.8;Corticotrophs: 140.4;Early spermatids: 121.3;Ependymal cells: 277.2;Lactotrophs: 85.9;Late spermatids: 153.1;Neutrophils: 149.8;Other brain neurons: 154.2;Pancreatic islet cells: 91.4;Respiratory ciliated cells: 240.2;Somatotrophs: 111.7;Thyrotrophs: 183.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 277.2;Glial cells: 190.9;Neuronal cells: 157.5;Neutrophils: 149.8;Pituitary endocrine cells: 183.9;Spermatogenic cell types: 153.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.6" "Lineage enhanced" "Detected in single" "granulocytes: 1.6" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Neurons: 1409494.8;Pancreatic islets: 499131.7" "Tissue enriched" "Detected in single" 3579 "cerebral cortex: 357870.8" "HPA015607, HPA076313" Enhanced Supported Approved Vesicles "Secreted in brain" "Developmental protein" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" Vesicles "HPA015607: , HPA076313: " "unprognostic (7.62e-2)" "unprognostic (9.61e-3)" "unprognostic (5.34e-2)" "unprognostic (8.98e-2)" "unprognostic (3.64e-1)" "unprognostic (3.99e-3)" "unprognostic (2.87e-1)" "unprognostic (2.78e-1)" "unprognostic (2.64e-2)" "unprognostic (2.11e-3)" "unprognostic (7.01e-2)" "unprognostic (1.51e-2)" KIAA0753 "MNR, OFIP" ENSG00000198920 KIAA0753 Q2KHM9 17 6578147-6640711 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 122.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 122.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 2814 "Fallopian tube cells: 428219.6;Granulosa cells: 134567.9" "Tissue enriched" "Detected in single" 364 "lung: 36441.8" "HPA023057, HPA023494" Enhanced Supported "Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 48 Centrosome "Primary cilium, Basal body, Cytosol" "HPA023057: , HPA023494: " "unprognostic (8.92e-2)" "unprognostic (9.25e-3)" "unprognostic (2.06e-1)" "unprognostic (4.21e-3)" "unprognostic (1.08e-2)" "unprognostic (4.42e-2)" "unprognostic (3.76e-1)" "unprognostic (2.58e-2)" "unprognostic (5.07e-2)" "unprognostic (2.48e-2)" "unprognostic (1.42e-1)" "unprognostic (3.30e-3)" "unprognostic (8.72e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (6.92e-2)" "unprognostic (1.07e-1)" "unprognostic (2.14e-1)" "unprognostic (4.16e-1)" "unprognostic (3.43e-2)" "unprognostic (1.82e-1)" "unprognostic (4.20e-1)" "unprognostic (5.47e-2)" "unprognostic (3.48e-3)" "unprognostic (7.71e-3)" "unprognostic (1.79e-2)" "unprognostic (1.37e-2)" "unprognostic (6.99e-3)" "unprognostic (3.14e-1)" "unprognostic (2.72e-1)" "unprognostic (9.29e-3)" "unprognostic (3.59e-1)" KIAA0930 "bK268H5.C22.1, C22orf9" ENSG00000100364 KIAA0930 Q6ICG6 22 45192244-45240894 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 183.3" "Cell type enhanced" "Detected in many" "Astrocytes: 261.2;Brain excitatory neurons: 112.9;Erythrocyte progenitors: 110.7;Monocyte progenitors: 151.5;Oligodendrocytes: 251.7;Other brain neurons: 130.4" "Cell type enhanced" "Detected in all" "Glial cells: 261.2;Mononuclear phagocytes: 151.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 11.0;eosinophil: 8.6;intermediate monocyte: 13.9;myeloid DC: 12.1;non-classical monocyte: 17.4;plasmacytoid DC: 10.1" "Group enriched" "Detected in all" 5 "dendritic cells: 12.1;granulocytes: 8.6;monocytes: 17.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in some" "bone marrow: 12422326.2;cerebral cortex: 11689171.0" HPA038091 Uncertain Approved "Nucleoplasm,Nuclear membrane,Mitochondria" No No "Cluster 29: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 22 "Nuclear membrane, Mitochondria" Nucleoplasm "HPA038091: " "unprognostic (2.28e-2)" "unprognostic (2.00e-1)" "unprognostic (3.52e-2)" "unprognostic (7.03e-2)" "unprognostic (1.72e-2)" "unprognostic (3.04e-2)" "unprognostic (4.51e-2)" "unprognostic (1.23e-1)" "unprognostic (2.01e-1)" "unprognostic (1.93e-3)" "unprognostic (1.66e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (3.06e-7)" "unprognostic (1.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.71e-1)" "unprognostic (7.69e-2)" "unprognostic (1.85e-2)" "unprognostic (5.99e-3)" "unprognostic (1.13e-1)" "unprognostic (2.32e-1)" "unprognostic (2.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-1)" "unprognostic (2.06e-2)" "unprognostic (4.50e-1)" "unprognostic (1.11e-1)" "unprognostic (6.66e-2)" "unprognostic (7.03e-3)" "unprognostic (2.91e-2)" KIAA1143 ENSG00000163807 KIAA1143 Q96AT1 3 44737661-44761619 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Early spermatids: 198.6;Late primary spermatocytes: 82.1;Late spermatids: 66.2" "Cell type enriched" "Detected in many" 13 "Spermatogenic cell types: 198.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 507521.3" "Tissue enhanced" "Detected in many" "skin: 4675440.6" "HPA045018, HPA061799" Approved Enhanced "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 Nucleoplasm "Cytokinetic bridge" "HPA045018: , HPA061799: " "potential prognostic favorable (2.24e-5)" "unprognostic (8.54e-2)" "unprognostic (3.77e-1)" "unprognostic (1.00e-1)" "unprognostic (1.62e-1)" "unprognostic (8.04e-2)" "unprognostic (5.20e-1)" "unprognostic (5.03e-2)" "unprognostic (2.71e-3)" "potential prognostic unfavorable (6.17e-5)" "potential prognostic favorable (1.35e-6)" "unprognostic (6.92e-3)" "unprognostic (3.85e-2)" "unprognostic (6.20e-3)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (1.34e-1)" "unprognostic (2.08e-1)" "unprognostic (9.34e-2)" "unprognostic (3.94e-1)" "unprognostic (1.25e-2)" "unprognostic (2.63e-1)" "unprognostic (4.31e-2)" "unprognostic (4.51e-2)" "unprognostic (4.95e-3)" "unprognostic (7.70e-3)" "unprognostic (1.85e-1)" "unprognostic (1.84e-1)" "unprognostic (1.74e-1)" "unprognostic (1.36e-2)" "unprognostic (4.20e-3)" KIAA1586 ENSG00000168116 KIAA1586 Q9HCI6 6 57046532-57055239 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 135.0;Erythrocyte progenitors: 80.2;Platelets: 72.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 135.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Cell type enriched" "Detected in single" 58 "Neurons: 5822.4" "Not detected" "Not detected" HPA036370 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" "Nucleoplasm, Nuclear membrane" "HPA036370: " "unprognostic (3.36e-2)" "unprognostic (1.87e-1)" "unprognostic (2.34e-1)" "unprognostic (3.73e-2)" "unprognostic (9.86e-2)" "unprognostic (1.74e-1)" "unprognostic (2.48e-2)" "unprognostic (1.48e-2)" "unprognostic (1.52e-1)" "unprognostic (3.29e-3)" "unprognostic (2.04e-3)" "unprognostic (4.91e-3)" "unprognostic (1.72e-1)" "unprognostic (1.78e-2)" "unprognostic (8.10e-3)" "unprognostic (1.84e-1)" "unprognostic (7.59e-2)" "unprognostic (3.05e-1)" "unprognostic (1.78e-1)" "unprognostic (6.82e-2)" "unprognostic (8.80e-2)" "unprognostic (6.43e-2)" "unprognostic (1.07e-3)" "unprognostic (4.26e-2)" "unprognostic (1.05e-1)" "unprognostic (5.68e-2)" "unprognostic (1.70e-3)" "unprognostic (1.83e-2)" "unprognostic (1.26e-1)" "unprognostic (1.45e-2)" "unprognostic (6.30e-2)" KIAA2026 FLJ20375 ENSG00000183354 KIAA2026 Q5HYC2 9 5881596-6008482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Choroid plexus epithelial cells: 1520.3" "Cell type enriched" "Detected in all" 5 "Ciliated cells: 1520.3" "Cell type enriched" "Detected in all" 4 "choroid plexus epithelial cell: 1292.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 86 "Neurons: 8644.0" "Not detected" "Not detected" HPA002109 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 101: Choroid plexus epithelial cells - Ion transport" "Vesicles, Cytosol" Nucleoplasm "HPA002109: " "unprognostic (2.15e-1)" "unprognostic (1.25e-1)" "unprognostic (9.73e-2)" "unprognostic (2.21e-1)" "unprognostic (3.10e-2)" "unprognostic (1.94e-3)" "unprognostic (9.24e-3)" "unprognostic (2.64e-1)" "unprognostic (2.43e-1)" "unprognostic (2.59e-1)" "potential prognostic favorable (2.24e-5)" "unprognostic (4.14e-3)" "unprognostic (6.96e-3)" "unprognostic (7.45e-3)" "unprognostic (1.87e-2)" "unprognostic (2.05e-2)" "unprognostic (1.69e-1)" "unprognostic (3.36e-1)" "unprognostic (1.62e-1)" "unprognostic (4.74e-2)" "unprognostic (1.90e-1)" "unprognostic (2.09e-1)" "unprognostic (4.98e-2)" "unprognostic (9.77e-2)" "unprognostic (1.11e-1)" "unprognostic (4.11e-2)" "unprognostic (1.93e-2)" "unprognostic (1.93e-1)" "unprognostic (1.89e-1)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" KICS2 "C12orf66, FLJ32549" ENSG00000174206 "KICSTOR subunit 2" Q96MD2 12 64186316-64222296 "Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2069 "Collecting ducts: 200743.6;Distal tubules: 243141.4;Fallopian tube cells: 176741.8" "Tissue enriched" "Detected in single" 1242 "lymphoid tissue: 124200.4" "HPA046743, HPA052855" Uncertain Approved "Lysosomes,Cytokinetic bridge" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 7 Lysosomes "Cytokinetic bridge" "HPA046743: , HPA052855: " "unprognostic (2.53e-2)" "unprognostic (3.11e-3)" "unprognostic (6.66e-3)" "unprognostic (9.75e-2)" "unprognostic (8.48e-2)" "unprognostic (2.44e-2)" "unprognostic (1.03e-1)" "unprognostic (6.21e-3)" "unprognostic (6.08e-3)" "unprognostic (4.90e-3)" "potential prognostic favorable (1.42e-4)" "unprognostic (2.11e-1)" "unprognostic (7.24e-2)" "unprognostic (4.19e-2)" "unprognostic (1.02e-1)" "unprognostic (2.44e-2)" "unprognostic (1.33e-3)" "unprognostic (6.47e-2)" "unprognostic (1.28e-1)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (3.12e-1)" "unprognostic (2.19e-1)" "unprognostic (2.95e-1)" "unprognostic (2.87e-2)" "unprognostic (4.58e-3)" "unprognostic (1.31e-1)" "unprognostic (3.22e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (9.76e-2)" KIF11 "Eg5, HKSP, KNSL1, TRIP5" ENSG00000138160 "Kinesin family member 11" P52732 10 92574105-92655395 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2;lymphoid tissue: 35.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 69.6;Erythrocyte progenitors: 145.3;Megakaryocyte progenitors: 90.1;Monocyte progenitors: 256.8;Neutrophil progenitors: 117.7" "Group enriched" "Detected in many" 4 "Erythrocytes: 145.3;Megakaryocytes: 90.1;Mononuclear phagocytes: 256.8;Neutrophils: 117.7;Spermatogenic cell types: 69.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" "Granulosa cells: 12796913.2" "Group enriched" "Detected in some" 10783 "bone marrow: 1222857.3;intestine: 1413561.5;lymphoid tissue: 598532.3" "HPA006916, HPA010093, HPA010568, CAB017617" Enhanced Supported "Vesicles,Mitotic spindle,Basal body,Cytosol,Mid piece,Principal piece,End piece" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 16 "Cytosol, Mid piece" "Vesicles, Mitotic spindle, Basal body, Principal piece, End piece" "CAB017617: , HPA006916: , HPA010093: , HPA010568: " "unprognostic (1.65e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-2)" "unprognostic (1.02e-1)" "unprognostic (3.10e-2)" "unprognostic (4.02e-1)" "unprognostic (3.88e-1)" "unprognostic (7.54e-2)" "unprognostic (5.38e-2)" "validated prognostic unfavorable (3.97e-4)" "validated prognostic unfavorable (4.41e-4)" "potential prognostic unfavorable (8.70e-10)" "validated prognostic unfavorable (7.61e-7)" "validated prognostic unfavorable (9.18e-5)" "potential prognostic unfavorable (7.79e-5)" "unprognostic (1.48e-2)" "unprognostic (7.72e-2)" "unprognostic (1.97e-1)" "unprognostic (3.93e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (8.86e-5)" "unprognostic (6.00e-3)" "unprognostic (7.17e-2)" "unprognostic (8.40e-2)" "unprognostic (4.03e-2)" "unprognostic (3.89e-2)" "unprognostic (1.91e-2)" "unprognostic (3.45e-1)" "unprognostic (1.94e-2)" "unprognostic (2.04e-1)" KIF12 ENSG00000136883 "Kinesin family member 12" 9 114086126-114099292 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "kidney: 214.1;pancreas: 91.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 115.3;Distal convoluted tubule cells: 94.5;Enteric stem cells: 47.0;Enterocytes: 54.2;Epididymal efferent duct absorptive cells: 62.9;Loop of henle epithelial cells: 93.6;Neuroendocrine cells: 86.6;Pancreatic duct cells: 66.8;Paneth cells: 54.1;Proximal tubule cells: 215.2;Renal collecting duct intercalated cells: 73.2;Renal collecting duct principal cells: 58.5;Renal connecting tubule cells: 97.5" "Cell type enhanced" "Detected in many" "Ductal cells: 115.3;Enteroendocrine cells: 86.6;Renal nephron cells: 215.2" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 12.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 96.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 23.3;liver cancer: 14.7" "Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020192, HPA024127" Uncertain Approved "Nucleoplasm,Mid piece,Principal piece" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Nucleoplasm, Mid piece, Principal piece" "HPA020192: , HPA024127: " "unprognostic (1.29e-3)" "unprognostic (2.51e-1)" "unprognostic (3.55e-2)" "unprognostic (5.48e-2)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (4.48e-2)" "unprognostic (1.63e-2)" "potential prognostic favorable (3.83e-5)" "unprognostic (1.15e-2)" "potential prognostic favorable (3.23e-6)" "unprognostic (5.30e-2)" "unprognostic (2.69e-1)" "unprognostic (4.09e-2)" "unprognostic (2.71e-2)" "unprognostic (2.70e-2)" "unprognostic (2.77e-1)" "unprognostic (2.42e-2)" "unprognostic (1.43e-2)" "unprognostic (9.48e-3)" "unprognostic (6.60e-2)" "unprognostic (1.50e-2)" "potential prognostic favorable (4.79e-4)" "unprognostic (2.87e-1)" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (9.59e-2)" "unprognostic (2.91e-1)" KIF14 KIAA0042 ENSG00000118193 "Kinesin family member 14" Q15058 1 200551497-200620751 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Meckel syndrome, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.2;lymphoid tissue: 10.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.4;Early primary spermatocytes: 57.5;Enteric transient amplifying cells: 47.3;Erythrocyte progenitors: 74.3;Esophageal basal cells: 31.6;Gastric progenitor cells: 30.8;Megakaryocyte progenitors: 66.3;Monocyte progenitors: 181.7;Neutrophil progenitors: 93.1;Paneth cells: 38.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 74.3;Megakaryocytes: 66.3;Mononuclear phagocytes: 181.7;Neutrophils: 93.1" "Cell type enhanced" "Detected in many" "lower rhombic lip: 5.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 644 "Granulosa cells: 59750.4;Oocytes: 69069.4" "Tissue enriched" "Detected in single" 417 "skeletal muscle: 41745.7" "HPA038061, HPA058220" Uncertain Supported "Plasma membrane,Midbody ring,Cytosol,Calyx,Connecting piece,Mid piece,Principal piece,End piece" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 57 "Cytosol, End piece" "Plasma membrane, Midbody ring, Calyx, Connecting piece, Mid piece, Principal piece" "HPA038061: , HPA058220: " "unprognostic (6.10e-2)" "unprognostic (1.48e-1)" "unprognostic (1.32e-1)" "unprognostic (5.21e-2)" "unprognostic (4.97e-2)" "unprognostic (2.01e-1)" "unprognostic (1.77e-1)" "unprognostic (4.53e-3)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (6.04e-4)" "validated prognostic unfavorable (2.84e-6)" "validated prognostic unfavorable (1.61e-4)" "unprognostic (1.44e-1)" "unprognostic (6.50e-2)" "unprognostic (3.85e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (2.01e-5)" "unprognostic (1.67e-3)" "unprognostic (3.64e-2)" "unprognostic (2.45e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-2)" "unprognostic (8.28e-2)" "unprognostic (1.39e-2)" KIF17 "KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3" ENSG00000117245 "Kinesin family member 17" Q9P2E2 1 20664014-20718017 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 21.0" "Cell type enhanced" "Detected in many" "Early spermatids: 56.5;Endometrial ciliated cells: 18.6;Ependymal cells: 41.8;Epididymal efferent duct ciliated cells: 26.4;Fallopian tube ciliated cells: 21.6;Late primary spermatocytes: 35.2;Late spermatids: 164.0;Lymphatic endothelial cells: 17.8;Respiratory ciliated cells: 30.4;Vascular endothelial cells: 18.2" "Group enriched" "Detected in many" 5 "Ciliated cells: 41.8;Spermatogenic cell types: 164.0" "Cell type enhanced" "Detected in many" "ependymal cell: 40.8" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 3.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 7790 "Neurons: 779042.4" "Group enriched" "Detected in some" 160 "cerebral cortex: 9590.0;intestine: 22494.8" HPA032085 Enhanced Approved "Nucleoplasm,Plasma membrane,Primary cilium tip,Basal body,Cytosol,Acrosome,Principal piece" NA NA "Cluster 67: Testis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Nucleoplasm "Plasma membrane, Primary cilium tip, Basal body, Cytosol, Acrosome, Principal piece" "HPA032085: " "unprognostic (2.19e-2)" "unprognostic (2.69e-2)" "potential prognostic favorable (3.20e-4)" "unprognostic (2.00e-1)" KIF18A "DKFZP434G2226, PPP1R99" ENSG00000121621 "Kinesin family member 18A" Q8NI77 11 28020619-28108156 "Essential proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 7.8;lymphoid tissue: 8.9;testis: 12.8" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 94.6;Erythrocyte progenitors: 72.4;Late primary spermatocytes: 92.8;Megakaryocyte progenitors: 79.7;Monocyte progenitors: 93.4;Neutrophil progenitors: 49.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 72.4;Megakaryocytes: 79.7;Mononuclear phagocytes: 93.4;Spermatogenic cell types: 94.6" "Cell type enhanced" "Detected in some" "vascular associated smooth muscle cell: 7.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 37793.2;Smooth muscle cells: 119362.3" "Not detected" "Not detected" "HPA039312, HPA039484" Approved Supported "Microtubules,Cytokinetic bridge" Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 20 "Microtubules, Cytokinetic bridge" "HPA039312: , HPA039484: " "unprognostic (2.07e-3)" "unprognostic (1.71e-1)" "unprognostic (5.85e-2)" "unprognostic (2.16e-1)" "unprognostic (2.40e-1)" "unprognostic (3.87e-3)" "unprognostic (2.87e-1)" "unprognostic (7.65e-2)" "unprognostic (2.93e-1)" "validated prognostic unfavorable (5.56e-8)" "validated prognostic unfavorable (3.15e-5)" "validated prognostic unfavorable (4.54e-6)" "validated prognostic unfavorable (8.13e-7)" "potential prognostic unfavorable (2.20e-5)" "unprognostic (2.00e-3)" "unprognostic (6.91e-2)" "unprognostic (3.12e-1)" "unprognostic (6.29e-2)" "unprognostic (2.50e-1)" "validated prognostic unfavorable (1.10e-4)" "validated prognostic unfavorable (4.29e-6)" "unprognostic (2.30e-2)" "unprognostic (5.83e-2)" "unprognostic (2.47e-2)" "unprognostic (1.61e-1)" "unprognostic (3.27e-1)" "unprognostic (1.83e-1)" "unprognostic (6.93e-3)" KIF18B ENSG00000186185 "Kinesin family member 18B" Q86Y91 17 44924709-44947773 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.9;lymphoid tissue: 13.4" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 22.8;Enteric transient amplifying cells: 22.6;Erythrocyte progenitors: 63.8;Esophageal basal cells: 16.3;Megakaryocyte progenitors: 40.1;Monocyte progenitors: 73.8;Neutrophil progenitors: 27.4;Oligodendrocyte progenitor cells: 12.9;Plasma cells: 12.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 63.8;Megakaryocytes: 40.1;Mononuclear phagocytes: 73.8;Neutrophils: 27.4" "Cell type enriched" "Detected in some" 14 "oligodendrocyte precursor cell: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in single" "white matter: 1.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 66 "Collecting ducts: 6571.8" "Tissue enriched" "Detected in single" 111 "cerebral cortex: 11113.2" HPA024205 Enhanced Supported "Nucleoplasm,Nucleoli,Nuclear bodies,Microtubule ends,Cytosol" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 13 "Nucleoplasm, Microtubule ends" "Nucleoli, Nuclear bodies, Cytosol" "HPA024205: " "unprognostic (6.90e-2)" "unprognostic (2.21e-1)" "unprognostic (3.31e-1)" "unprognostic (6.31e-3)" "unprognostic (1.67e-1)" "unprognostic (3.07e-2)" "unprognostic (3.85e-1)" "unprognostic (8.27e-2)" "unprognostic (3.54e-2)" "validated prognostic unfavorable (1.10e-11)" "validated prognostic unfavorable (7.94e-8)" "potential prognostic unfavorable (1.39e-7)" "validated prognostic unfavorable (1.05e-6)" "validated prognostic unfavorable (8.91e-5)" "validated prognostic unfavorable (5.75e-6)" "validated prognostic unfavorable (2.95e-4)" "unprognostic (2.02e-1)" "unprognostic (1.88e-3)" "unprognostic (8.25e-2)" "unprognostic (7.67e-2)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.28e-3)" "unprognostic (8.12e-2)" "unprognostic (4.40e-2)" "unprognostic (3.80e-3)" "unprognostic (1.06e-2)" "unprognostic (1.33e-1)" "unprognostic (2.55e-2)" KIF20A "MKLP2, RAB6KIFL" ENSG00000112984 "Kinesin family member 20A" O95235 5 138178719-138187723 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.3;lymphoid tissue: 22.9;testis: 10.9" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 13.3;Differentiating spermatogonia: 11.9;Early primary spermatocytes: 17.1;Enteric transient amplifying cells: 9.5;Erythrocyte progenitors: 22.5;Esophageal basal cells: 11.5;Extravillous trophoblasts: 14.0;Gastric progenitor cells: 16.7;Hofbauer cells: 9.2;Late primary spermatocytes: 13.6;Megakaryocyte progenitors: 14.4;Migrating cytotrophoblasts: 15.1;Monocyte progenitors: 39.1;Neutrophil progenitors: 13.5;Oocytes: 13.8" "Cell type enhanced" "Detected in many" "Erythrocytes: 22.5;Mononuclear phagocytes: 39.1;Proliferating cells: 16.7;Spermatogenic cell types: 17.1" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 12 "NK-cell: 6.7;T-reg: 2.5" "Group enriched" "Detected in many" 46 "NK-cells: 6.7;T-cells: 2.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 7785562.4" "Tissue enriched" "Detected in single" 613 "bone marrow: 61274.8" "HPA036909, HPA036910" Approved Approved "Nucleoplasm,Cytokinetic bridge,Cleavage furrow,Mitotic spindle" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 26 "Nucleoplasm, Cytokinetic bridge, Cleavage furrow, Mitotic spindle" "HPA036909: , HPA036910: " "unprognostic (6.91e-3)" "unprognostic (7.53e-2)" "unprognostic (1.21e-1)" "unprognostic (7.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.50e-1)" "unprognostic (1.16e-1)" "unprognostic (4.61e-2)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (1.17e-5)" "validated prognostic unfavorable (8.01e-11)" "validated prognostic unfavorable (1.58e-6)" "potential prognostic unfavorable (5.78e-12)" "validated prognostic unfavorable (2.10e-9)" "validated prognostic unfavorable (1.50e-7)" "validated prognostic unfavorable (1.58e-5)" "validated prognostic unfavorable (4.64e-5)" "unprognostic (1.37e-1)" "unprognostic (2.03e-1)" "unprognostic (2.17e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (2.06e-5)" "unprognostic (1.78e-3)" "unprognostic (1.03e-1)" "unprognostic (6.51e-2)" "unprognostic (1.64e-1)" "unprognostic (9.01e-2)" "unprognostic (1.85e-1)" "unprognostic (1.46e-1)" "unprognostic (9.84e-2)" "unprognostic (4.39e-2)" KIF20B "CT90, KRMP1, MPHOSPH1, MPP1" ENSG00000138182 "Kinesin family member 20B" Q96Q89 10 89701590-89774939 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.6;lymphoid tissue: 9.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 136.5;Early primary spermatocytes: 186.7;Erythrocyte progenitors: 233.4;Megakaryocyte progenitors: 135.3;Monocyte progenitors: 233.5" "Cell type enhanced" "Detected in all" "Erythrocytes: 233.4;Mononuclear phagocytes: 233.5;Spermatogenic cell types: 186.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 73.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 50228 "Granulosa cells: 5022822.6" "Group enriched" "Detected in some" 8104 "fallopian tube: 852947.7;skeletal muscle: 767833.9" HPA050214 Supported Supported "Nucleoplasm,Cytokinetic bridge,Midbody,Centrosome,Basal body,Cytosol,Perinuclear theca" Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 15: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 8 "Nucleoplasm, Cytokinetic bridge, Basal body" "Midbody, Centrosome, Cytosol, Perinuclear theca" "HPA050214: " "unprognostic (1.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.44e-1)" "unprognostic (6.48e-2)" "unprognostic (2.42e-2)" "unprognostic (2.14e-1)" "unprognostic (8.55e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (1.26e-4)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (8.47e-4)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (6.50e-3)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (1.03e-2)" "unprognostic (4.18e-3)" "validated prognostic unfavorable (1.82e-5)" "validated prognostic unfavorable (3.64e-7)" "unprognostic (2.75e-3)" "unprognostic (1.48e-2)" "unprognostic (2.04e-1)" "unprognostic (2.04e-2)" "unprognostic (1.12e-1)" "unprognostic (8.42e-2)" KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.3;brain: 19.3;retina: 19.9" "Cell type enhanced" "Detected in many" "Astrocytes: 36.2;Cone photoreceptor cells: 58.0;Early spermatids: 47.0;Late spermatids: 157.0;Microglia: 33.7;Müller glia: 101.1;Neutrophil progenitors: 76.8;Neutrophils: 86.1;NK-cells: 39.6;Retinal bipolar cells: 41.1;Retinal pigment epithelial cells: 38.4;Rod photoreceptor cells: 42.1;T-cells: 33.0" "Cell type enhanced" "Detected in many" "Glial cells: 101.1;Neuronal cells: 58.0;Neutrophils: 86.1;Spermatogenic cell types: 157.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Group enriched" "Detected in many" 8 "Leukemia: 30.9;lymphoma: 31.2;Myeloma: 75.3" "Colon - T-cells, Kidney - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 4186270.0;Microglia and Neuropil: 4046227.0;Neurons: 3619092.2;Neutrophils: 2514747.6" "Tissue enriched" "Detected in some" "bone marrow: 7697983.0" "HPA027249, HPA027274" Approved Uncertain "Plasma membrane,Mitotic spindle,Cytosol,Mid piece" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "Plasma membrane, Mid piece" "Mitotic spindle, Cytosol" "HPA027249: , HPA027274: " "unprognostic (1.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.24e-3)" "unprognostic (6.62e-2)" "unprognostic (5.65e-2)" "unprognostic (8.30e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (4.78e-4)" "unprognostic (3.35e-3)" "unprognostic (8.61e-2)" "unprognostic (7.40e-2)" "unprognostic (1.09e-2)" "unprognostic (1.41e-2)" "unprognostic (2.05e-2)" "unprognostic (4.43e-2)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (1.87e-1)" "unprognostic (5.05e-2)" "unprognostic (1.32e-1)" "unprognostic (2.17e-1)" "unprognostic (1.69e-1)" "unprognostic (3.07e-1)" "unprognostic (1.20e-2)" "unprognostic (1.84e-1)" KIF23 "KNSL5, MKLP-1, MKLP1" ENSG00000137807 "Kinesin family member 23" Q02241 15 69414246-69448427 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 20.4;lymphoid tissue: 14.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 41.7;Differentiating spermatogonia: 34.8;Early primary spermatocytes: 45.5;Enteric transient amplifying cells: 33.7;Erythrocyte progenitors: 86.7;Extravillous trophoblasts: 49.4;Late primary spermatocytes: 60.8;Megakaryocyte progenitors: 36.1;Migrating cytotrophoblasts: 52.5;Monocyte progenitors: 74.3;Neutrophil progenitors: 36.2" "Cell type enhanced" "Detected in many" "Erythrocytes: 86.7;Mononuclear phagocytes: 74.3;Spermatogenic cell types: 60.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 14.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 4 "choroid plexus: 2.9" "Immune cell enhanced" "Detected in some" "eosinophil: 4.6" "Group enriched" "Detected in many" 13 "granulocytes: 4.6;monocytes: 1.2;T-cells: 1.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Smooth muscle cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 12385 "Granulosa cells: 1238504.0" "Tissue enriched" "Detected in single" 948 "bone marrow: 94799.2" "CAB010414, HPA045208, HPA068831" Uncertain Supported "Nucleoplasm,Midbody ring,Mitotic spindle,Mid piece,Principal piece,Annulus" Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 78 Nucleoplasm "Midbody ring, Mitotic spindle, Mid piece, Principal piece, Annulus" "CAB010414: , HPA045208: , HPA068831: " "unprognostic (3.17e-2)" "unprognostic (1.43e-1)" "unprognostic (9.49e-2)" "unprognostic (1.32e-1)" "unprognostic (9.50e-2)" "unprognostic (1.48e-1)" "unprognostic (1.88e-1)" "unprognostic (2.79e-2)" "unprognostic (5.14e-2)" "potential prognostic unfavorable (1.64e-4)" "validated prognostic unfavorable (3.72e-10)" "validated prognostic unfavorable (2.37e-6)" "potential prognostic unfavorable (1.50e-7)" "validated prognostic unfavorable (9.80e-6)" "validated prognostic unfavorable (6.19e-7)" "validated prognostic unfavorable (4.08e-6)" "validated prognostic unfavorable (1.82e-4)" "unprognostic (9.01e-2)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.80e-2)" "validated prognostic unfavorable (2.85e-5)" "validated prognostic unfavorable (9.51e-5)" "unprognostic (3.17e-2)" "unprognostic (1.69e-2)" "unprognostic (1.72e-2)" "unprognostic (1.93e-2)" "unprognostic (3.27e-2)" "unprognostic (1.53e-1)" "unprognostic (5.97e-2)" KIF26B FLJ10157 ENSG00000162849 "Kinesin family member 26B" Q2KJY2 1 245154985-245709432 "Predicted intracellular proteins" "Developmental protein, Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 167.8;Brain inhibitory neurons: 183.5;Endometrial stromal cells: 217.7;Loop of henle epithelial cells: 156.0;Microglia: 244.9;Oligodendrocyte progenitor cells: 565.4;Other brain neurons: 141.3;Papillary tip epithelial cells: 212.1;Proximal tubule cells: 215.0;Renal collecting duct principal cells: 477.6;Renal connecting tubule cells: 237.1" "Cell type enhanced" "Detected in many" "Ductal cells: 477.6;Glial cells: 565.4;Stromal cells: 217.7" "Cell type enhanced" "Detected in all" "MGE interneuron: 774.3;oligodendrocyte precursor cell: 654.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 18 "dendritic cells: 1.8" "Cancer enriched" "Detected in many" 5 "Neuroblastoma: 18.4" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Alveolar cell types: 1791796.1;Oocytes: 463151.9" "Group enriched" "Detected in some" "fallopian tube: 1107245.7;Stomach: 2682457.7" "HPA027709, HPA028478, HPA028561, HPA028562" Enhanced Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 2 "Microtubules, Primary cilium" "Plasma membrane, Cytokinetic bridge" "HPA027709: , HPA028478: , HPA028561: , HPA028562: " "potential prognostic favorable (1.11e-4)" "unprognostic (1.96e-1)" "unprognostic (6.83e-3)" "unprognostic (5.97e-3)" "unprognostic (1.57e-2)" "unprognostic (9.28e-2)" "unprognostic (4.17e-2)" "unprognostic (1.06e-2)" "unprognostic (5.53e-2)" "unprognostic (1.40e-1)" "unprognostic (4.06e-1)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (1.96e-1)" "validated prognostic unfavorable (6.64e-4)" "validated prognostic unfavorable (4.16e-7)" "unprognostic (7.25e-3)" "unprognostic (7.63e-2)" "unprognostic (1.41e-1)" "unprognostic (4.01e-2)" "unprognostic (1.58e-1)" "unprognostic (8.70e-2)" "unprognostic (4.31e-2)" "unprognostic (1.42e-1)" KIF2A "HK2, KIF2" ENSG00000068796 "Kinesin family member 2A" O00139 5 62306162-62391025 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Neurogenesis" "Developmental protein, Motor protein" "Cancer-related genes, Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Megakaryocytes: 457.4;Platelets: 1557.0" "Group enriched" "Detected in all" 6 "Megakaryocytes: 457.4;Platelets: 1557.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 43041003.2" "Tissue enriched" "Detected in many" "cerebral cortex: 59279852.0" "HPA004715, HPA004716" Approved Supported "Nucleoplasm,Nucleoli,Mitotic spindle,Centrosome,Basal body,Cytosol,Mid piece,Principal piece,Annulus" Yes No 350000 "Cluster 1: T-cells - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 47: Platelets - Hemostasis" 42 "Nucleoplasm, Nucleoli, Centrosome, Basal body, Annulus" "Mitotic spindle, Cytosol, Mid piece, Principal piece" "HPA004715: , HPA004716: " "unprognostic (1.85e-1)" "unprognostic (8.24e-2)" "unprognostic (4.52e-1)" "unprognostic (1.71e-1)" "unprognostic (8.71e-3)" "unprognostic (2.11e-2)" "unprognostic (2.11e-1)" "unprognostic (1.89e-2)" "unprognostic (2.79e-3)" "potential prognostic unfavorable (9.89e-6)" "unprognostic (1.25e-3)" "unprognostic (6.55e-3)" "unprognostic (6.76e-2)" "potential prognostic unfavorable (1.96e-4)" "unprognostic (2.68e-3)" "unprognostic (9.74e-2)" "unprognostic (1.62e-3)" "unprognostic (2.14e-2)" "unprognostic (4.43e-1)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (4.38e-5)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (1.14e-1)" "unprognostic (2.73e-2)" "unprognostic (1.48e-1)" "unprognostic (1.01e-1)" "unprognostic (1.23e-1)" "unprognostic (1.94e-1)" "unprognostic (6.24e-2)" "unprognostic (1.32e-1)" KIF2B ENSG00000141200 "Kinesin family member 2B" Q8N4N8 17 53822927-53825193 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 705 "testis: 70.5" "Group enriched" "Detected in some" 127 "Early spermatids: 817.0;Late primary spermatocytes: 239.8;Late spermatids: 765.2" "Cell type enriched" "Detected in some" 171 "Spermatogenic cell types: 817.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 1691 "Cardiomyocytes: 127552.3;Smooth muscle cells: 210590.3" "Not detected" "Not detected" "HPA023081, HPA023103, HPA024795" Uncertain Uncertain "Nucleoli,Microtubules,Cytokinetic bridge,Mitotic spindle,Mid piece,Principal piece,End piece" Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 "Microtubules, Cytokinetic bridge, Mitotic spindle" "Nucleoli, Mid piece, Principal piece, End piece" "HPA023081: , HPA023103: , HPA024795: " KIF2C "CT139, KNSL6, MCAK" ENSG00000142945 "Kinesin family member 2C" Q99661 1 44739818-44767767 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 31.1;lymphoid tissue: 34.8;testis: 72.6" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3084.5" "Cell type enriched" "Detected in many" 22 "Spermatogenic cell types: 3084.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Region enhanced" "Detected in some" "white matter: 2.1" "Not detected" "Not detected" "Group enriched" "Detected in some" "Granulosa cells: 474854.1;Oocytes: 1341000.4" "Tissue enriched" "Detected in single" 44853 "bone marrow: 4485274.2" "HPA006219, HPA079172, CAB080091" Enhanced Approved Nucleoplasm,Midbody,Centrosome,Cytosol Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 39: Testis - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 21 "Nucleoplasm, Midbody, Centrosome" Cytosol "CAB080091: , HPA006219: , HPA079172: " "unprognostic (3.89e-2)" "unprognostic (7.14e-2)" "unprognostic (1.64e-2)" "unprognostic (2.04e-1)" "unprognostic (2.45e-2)" "unprognostic (2.41e-2)" "unprognostic (3.60e-1)" "unprognostic (5.59e-2)" "unprognostic (2.08e-1)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (1.25e-7)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (1.49e-8)" "validated prognostic unfavorable (6.27e-8)" "validated prognostic unfavorable (5.57e-8)" "validated prognostic unfavorable (2.61e-4)" "validated prognostic unfavorable (2.26e-5)" "unprognostic (1.01e-1)" "unprognostic (2.05e-1)" "unprognostic (1.75e-1)" "unprognostic (9.29e-3)" "potential prognostic unfavorable (6.70e-4)" "unprognostic (5.27e-2)" "unprognostic (5.80e-2)" "unprognostic (3.13e-2)" "unprognostic (1.29e-2)" "unprognostic (4.21e-3)" "unprognostic (6.68e-2)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "unprognostic (2.25e-1)" KIF3A "FLA10, KLP-20" ENSG00000131437 "Kinesin family member 3A" Q9Y496 5 132692628-132737638 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 40.4;retina: 31.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 194.0;Brain inhibitory neurons: 190.0;Gonadotrophs: 202.7;Other brain neurons: 195.2;Respiratory ciliated cells: 204.6;Retinal horizontal cells: 220.4" "Cell type enhanced" "Detected in all" "Ciliated cells: 204.6;Neuronal cells: 220.4;Pituitary endocrine cells: 202.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "basophil: 68.3" "Lineage enriched" "Detected in all" 10 "granulocytes: 68.3" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 14030584.4;Microglia and Neuropil: 16754288.1;Neurons: 17851353.5" "Group enriched" "Detected in many" "cerebral cortex: 9677335.2;Stomach: 2515467.1" "CAB037085, HPA063063" Approved Approved "Nucleoplasm,Primary cilium,Basal body,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 31 "Nucleoplasm, Primary cilium, Basal body, Cytosol" "CAB037085: , HPA063063: " "unprognostic (2.37e-2)" "unprognostic (1.11e-3)" "unprognostic (1.85e-1)" "unprognostic (4.60e-3)" "unprognostic (1.51e-2)" "unprognostic (1.82e-1)" "unprognostic (8.74e-2)" "unprognostic (5.28e-3)" "unprognostic (3.10e-1)" "unprognostic (7.63e-2)" "potential prognostic favorable (1.76e-5)" "unprognostic (1.54e-2)" "unprognostic (1.46e-1)" "unprognostic (1.83e-3)" "unprognostic (6.41e-3)" "unprognostic (8.61e-2)" "unprognostic (1.35e-1)" "unprognostic (9.53e-3)" "unprognostic (9.00e-2)" "unprognostic (8.15e-2)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (4.26e-2)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (9.89e-2)" "unprognostic (1.56e-1)" "unprognostic (1.19e-1)" "unprognostic (5.43e-2)" "unprognostic (2.08e-2)" "unprognostic (1.57e-1)" "unprognostic (9.86e-2)" "unprognostic (4.01e-2)" KIF3B "FLA8, KIAA0359, KLP-11" ENSG00000101350 "Kinesin family member 3B" O15066 20 32277651-32335011 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein" "Ciliopathy, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 156.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 18223045.3;Neurons: 19182730.7" "Tissue enhanced" "Detected in many" "cerebral cortex: 18320687.1" HPA007119 Approved Approved "Nucleoplasm,Primary cilium tip,Cytosol,Connecting piece,Flagellar centriole" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 79: Photoreceptor cells - Phototransduction" 15 "Nucleoplasm, Primary cilium tip, Flagellar centriole" "Cytosol, Connecting piece" "HPA007119: " "unprognostic (1.97e-2)" "unprognostic (3.19e-3)" "unprognostic (9.42e-2)" "unprognostic (3.75e-3)" "unprognostic (1.44e-1)" "unprognostic (5.79e-2)" "unprognostic (3.17e-1)" "unprognostic (1.24e-2)" "unprognostic (2.74e-1)" "unprognostic (2.69e-1)" "validated prognostic favorable (5.77e-10)" "validated prognostic favorable (1.58e-4)" "potential prognostic favorable (1.06e-4)" "unprognostic (2.78e-2)" "unprognostic (4.41e-2)" "unprognostic (2.04e-1)" "unprognostic (3.52e-3)" "unprognostic (4.02e-2)" "unprognostic (9.35e-2)" "unprognostic (8.48e-3)" "unprognostic (4.67e-3)" "unprognostic (8.95e-2)" "unprognostic (2.31e-1)" "unprognostic (5.89e-2)" "potential prognostic favorable (3.93e-4)" "unprognostic (7.50e-2)" "unprognostic (2.22e-1)" "unprognostic (6.91e-2)" "unprognostic (4.79e-1)" "unprognostic (4.05e-2)" "unprognostic (1.74e-1)" KIF4A "FLJ12530, FLJ12655, FLJ14204, FLJ20631, HSA271784, KIF4, KIF4-G1, MRX100" ENSG00000090889 "Kinesin family member 4A" O95239 X 70290104-70420886 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA-binding, Motor protein" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 10.6;lymphoid tissue: 11.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 31.1;Enteric transient amplifying cells: 33.3;Ependymal cells: 42.8;Erythrocyte progenitors: 88.8;Extravillous trophoblasts: 25.1;Fallopian tube ciliated cells: 26.3;Hepatic stellate cells: 25.8;Megakaryocyte progenitors: 62.2;Monocyte progenitors: 107.6;Neutrophil progenitors: 53.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 88.8;Megakaryocytes: 62.2;Mononuclear phagocytes: 107.6;Neutrophils: 53.6" "Cell type enriched" "Detected in many" 14 "ependymal cell: 52.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Thyrotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in some" "Granulosa cells: 6268496.9;Neutrophils: 1946780.7" "Tissue enriched" "Detected in some" "bone marrow: 2110325.4" "HPA034745, HPA034746, HPA061583" Approved Approved "Nucleoplasm,Midbody,Acrosome,Equatorial segment,Mid piece,Principal piece" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 46: Brainstem - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 15 "Nucleoplasm, Midbody" "Acrosome, Equatorial segment, Mid piece, Principal piece" "HPA034745: , HPA034746: , HPA061583: " "unprognostic (9.60e-3)" "unprognostic (1.99e-2)" "unprognostic (2.15e-1)" "unprognostic (4.48e-2)" "unprognostic (1.11e-1)" "unprognostic (2.05e-1)" "unprognostic (4.03e-1)" "unprognostic (9.23e-2)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (8.60e-5)" "validated prognostic unfavorable (5.64e-8)" "validated prognostic unfavorable (2.40e-6)" "validated prognostic unfavorable (2.45e-7)" "validated prognostic unfavorable (1.01e-10)" "validated prognostic unfavorable (2.08e-4)" "validated prognostic unfavorable (3.22e-4)" "unprognostic (2.81e-2)" "unprognostic (7.69e-2)" "unprognostic (1.48e-1)" "unprognostic (3.75e-2)" "potential prognostic unfavorable (1.60e-6)" "unprognostic (1.84e-2)" "unprognostic (3.57e-2)" "unprognostic (3.64e-3)" "unprognostic (5.94e-2)" "unprognostic (9.73e-2)" "unprognostic (1.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.22e-2)" KIF4B ENSG00000226650 "Kinesin family member 4B" Q2VIQ3 5 155013755-155018141 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 3.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Early spermatids: 4.5;Late primary spermatocytes: 22.4;Late spermatids: 6.8" "Cell type enriched" "Detected in some" 10 "Spermatogenic cell types: 22.4" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Cell type enriched" "Detected in single" 642 "Granulosa cells: 64200.3" "Not detected" "Not detected" "HPA034745, HPA034746, HPA061583" Uncertain Approved "Nucleoplasm,Midbody,Acrosome,Equatorial segment,Mid piece,Principal piece" Yes NA "Cluster 57: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Nucleoplasm, Midbody" "Acrosome, Equatorial segment, Mid piece, Principal piece" "HPA034745: , HPA034746: , HPA061583: " KIF5A "D12S1889, MY050, NKHC, SPG10" ENSG00000155980 "Kinesin family member 5A" Q12840 12 57546026-57586633 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Hydrolase, Isomerase, Motor protein" "Amyotrophic lateral sclerosis, Disease variant, Epilepsy, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "brain: 1437.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 98.4;Brain inhibitory neurons: 87.3;Cardiomyocytes: 100.4;Corticotrophs: 41.3;Early spermatids: 51.6;Epicardial cells: 36.4;Late spermatids: 60.3;Other brain neurons: 124.9;Retinal bipolar cells: 43.3;Retinal ganglion cells: 104.3;Retinal horizontal cells: 54.1" "Cell type enhanced" "Detected in many" "Myocytes: 100.4;Neuronal cells: 124.9;Spermatogenic cell types: 60.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 11 "Glioblastoma Multiforme (TCGA): 83.7;Testicular Germ Cell Tumor (TCGA): 23.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 31.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Fibroblasts, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 78282 "Astrocytes and Neuropil: 9737476.0;Microglia and Neuropil: 6889272.1;Neurons: 6857930.3" "Tissue enriched" "Detected in single" 221649 "cerebral cortex: 22164920.7" "HPA004469, HPA073448" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitotic spindle,Cytosol,Mid piece,Principal piece" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 19 "Nucleoplasm, Cytosol" "Plasma membrane, Mitotic spindle, Mid piece, Principal piece" "HPA004469: , HPA073448: " "unprognostic (1.18e-1)" "unprognostic (7.15e-2)" "unprognostic (3.24e-1)" "unprognostic (4.02e-2)" "unprognostic (8.46e-2)" "unprognostic (6.95e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (7.58e-5)" "unprognostic (1.02e-1)" "unprognostic (1.08e-1)" "unprognostic (1.19e-1)" "unprognostic (1.40e-2)" "unprognostic (1.50e-1)" "unprognostic (3.43e-2)" "unprognostic (3.76e-3)" "unprognostic (3.55e-2)" "unprognostic (5.43e-3)" "unprognostic (1.33e-1)" "unprognostic (4.76e-2)" "unprognostic (1.06e-1)" "unprognostic (2.34e-1)" "unprognostic (1.74e-3)" "unprognostic (2.56e-2)" "unprognostic (4.56e-1)" "unprognostic (8.52e-3)" KIF6 "C6orf102, dJ1043E3.1, dJ137F1.4, dJ188D3.1, DKFZp451I2418, MGC33317" ENSG00000164627 "Kinesin family member 6" Q6ZMV9 6 39329990-39725408 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;fallopian tube: 3.6;testis: 4.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 134.8;Ependymal cells: 454.0;Epididymal efferent duct ciliated cells: 81.8;Fallopian tube ciliated cells: 158.9;Oligodendrocytes: 325.1;Respiratory ciliated cells: 321.7;Rod photoreceptor cells: 85.4;Thyrotrophs: 85.6" "Group enriched" "Detected in many" 4 "Ciliated cells: 454.0;Glial cells: 325.1" "Cell type enhanced" "Detected in all" "ependymal cell: 477.7;oligodendrocyte: 443.9" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 3.5;Skin Cutaneous Melanoma (TCGA): 3.9;Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "skin cancer: 9.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 11237 "Fallopian tube cells: 1123734.0" "Tissue enriched" "Detected in single" 47 "pancreas: 4727.4" "HPA038811, HPA058624" Enhanced Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA038811: , HPA058624: " "unprognostic (1.27e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (2.76e-1)" "unprognostic (1.07e-1)" "unprognostic (1.29e-1)" "unprognostic (8.76e-2)" KIF7 JBTS12 ENSG00000166813 "Kinesin family member 7" Q2M1P5 15 89608789-89663086 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein, Repressor" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 37.4;Astrocytes: 27.6;Fibro-adipogenic progenitors: 26.3" "Cell type enhanced" "Detected in many" "Adipocytes: 37.4" "Cell type enhanced" "Detected in many" "astrocyte: 31.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2956 "Granulosa cells: 147670.0;Oocytes: 443501.8" "Tissue enriched" "Detected in single" 3661 "blood vessel: 366116.5" HPA043145 Approved Supported "Nucleoli fibrillar center,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 74: Non-specific - Signal transduction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 18 "Primary cilium, Primary cilium tip" "Nucleoli fibrillar center, Cytosol" "HPA043145: " "unprognostic (3.13e-1)" "unprognostic (5.07e-2)" "unprognostic (3.13e-1)" "unprognostic (1.08e-2)" "unprognostic (1.15e-2)" "unprognostic (5.07e-1)" "unprognostic (1.07e-1)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.45e-1)" "unprognostic (5.74e-3)" "potential prognostic unfavorable (9.05e-5)" "unprognostic (2.00e-1)" "unprognostic (1.32e-1)" "unprognostic (1.27e-3)" "unprognostic (1.33e-1)" "unprognostic (1.41e-2)" "unprognostic (3.04e-2)" "unprognostic (4.89e-2)" "unprognostic (2.39e-1)" "unprognostic (1.15e-1)" "unprognostic (8.13e-3)" "unprognostic (4.99e-2)" "unprognostic (2.34e-1)" "unprognostic (7.00e-2)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" KIF9 MGC104186 ENSG00000088727 "Kinesin family member 9" Q9HAQ2 3 47227998-47283451 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 107.2;testis: 60.4" "Cell type enhanced" "Detected in many" "Early spermatids: 637.2;Endometrial ciliated cells: 460.6;Epididymal efferent duct ciliated cells: 753.0;Fallopian tube ciliated cells: 455.4;Late primary spermatocytes: 1062.5;Respiratory ciliated cells: 378.8" "Group enriched" "Detected in all" 5 "Ciliated cells: 753.0;Spermatogenic cell types: 1062.5" "Cell type enhanced" "Detected in all" "ependymal cell: 154.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15718 "Fallopian tube cells: 1571825.7" "Tissue enriched" "Detected in some" "pancreas: 902557.3" "HPA022031, HPA022033, HPA030429" Approved Approved "Primary cilium,Primary cilium tip,Cytosol,Mid piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 107: Ciliated cells - Cilia assembly & function" 44 "Primary cilium, Primary cilium tip, Cytosol" "Mid piece" "HPA022031: , HPA022033: , HPA030429: " "unprognostic (6.13e-2)" "unprognostic (9.40e-2)" "unprognostic (1.77e-2)" "potential prognostic favorable (3.51e-7)" "unprognostic (3.71e-1)" "unprognostic (1.60e-2)" "unprognostic (1.54e-2)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (4.69e-2)" "potential prognostic unfavorable (2.25e-4)" "validated prognostic favorable (1.79e-4)" "validated prognostic favorable (1.28e-4)" "potential prognostic favorable (4.19e-5)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (8.76e-2)" "unprognostic (1.43e-1)" "unprognostic (2.31e-1)" "unprognostic (4.07e-1)" "unprognostic (1.52e-1)" "unprognostic (2.27e-2)" "unprognostic (7.27e-2)" "unprognostic (3.55e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-1)" "unprognostic (4.02e-3)" "unprognostic (7.37e-3)" "unprognostic (2.48e-1)" "unprognostic (9.64e-3)" "unprognostic (1.18e-1)" "unprognostic (7.93e-2)" "unprognostic (3.34e-2)" KIFAP3 "FLA3, KAP-1, KAP3, SMAP" ENSG00000075945 "Kinesin associated protein 3" Q92845 1 169921326-170085208 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 319.2;Platelets: 395.1" "Cell type enhanced" "Detected in all" "Platelets: 395.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 9846117.9" "Tissue enhanced" "Detected in many" "cerebral cortex: 1245189.5;fallopian tube: 1046299.0;lymphoid tissue: 1032766.4" "HPA023738, HPA023742" Supported Approved "Nucleoplasm,Microtubules,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 39 "Microtubules, Basal body" Nucleoplasm "HPA023738: , HPA023742: " "unprognostic (3.53e-2)" "unprognostic (5.95e-2)" "unprognostic (1.93e-2)" "unprognostic (5.75e-2)" "unprognostic (1.00e-1)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (9.56e-2)" "unprognostic (3.51e-1)" "unprognostic (3.25e-2)" "potential prognostic favorable (3.55e-5)" "unprognostic (2.51e-3)" "unprognostic (4.22e-2)" "unprognostic (3.98e-3)" "unprognostic (3.68e-1)" "unprognostic (2.14e-1)" "unprognostic (2.28e-1)" "unprognostic (7.81e-3)" "unprognostic (3.75e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (6.68e-5)" "unprognostic (1.14e-1)" "unprognostic (5.85e-2)" "unprognostic (1.68e-1)" "unprognostic (2.91e-1)" "unprognostic (7.65e-2)" "unprognostic (1.28e-2)" "unprognostic (7.08e-3)" "unprognostic (4.66e-2)" "unprognostic (1.45e-2)" "unprognostic (3.70e-1)" KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657267-54740783 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 79.2" "Cell type enhanced" "Detected in many" "Breast secretory cells: 230.0;Innate lymphoid cells: 512.9;Mast cells: 1765.7;Melanocytes: 649.5;Renal collecting duct intercalated cells: 569.2;Respiratory ionocytes: 396.2;Salivary ionocytes: 263.8;Tuft cells: 253.6" "Cell type enhanced" "Detected in many" "Ductal cells: 569.2;Innate lymphoid cells: 512.9;Mast cells: 1765.7;Pigment cells: 649.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 699.5;CGE interneuron: 325.6;midbrain-derived inhibitory: 571.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 143.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 16.1;eosinophil: 9.6;NK-cell: 11.1" "Group enriched" "Detected in many" 7 "granulocytes: 16.1;NK-cells: 11.1" "Cancer enhanced" "Detected in many" "Leukemia: 28.3" "Adipose subcutaneous - Mast cells, Lung - Mast cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Oocytes: 9387301.0;Smooth muscle cells: 19739938.0" "Tissue enriched" "Detected in some" "cerebral cortex: 2247494.4" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Nucleoli fibrillar center,Plasma membrane" NA NA 33000000 "Cluster 32: Basophils - Transcription" "Cluster 55: Breast - Lactation" "Cluster 35: Non-specific - DNA binding" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 42 "Plasma membrane" "Nucleoli fibrillar center" "CAB003288: , CAB068253: , CAB072867: , HPA004471: , HPA073252: " "unprognostic (7.25e-2)" "unprognostic (1.24e-2)" "unprognostic (1.08e-1)" "unprognostic (3.57e-1)" "unprognostic (2.82e-1)" "unprognostic (4.48e-2)" "unprognostic (1.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.25e-2)" "unprognostic (1.60e-1)" "validated prognostic favorable (7.36e-5)" "validated prognostic favorable (6.08e-5)" "unprognostic (2.94e-1)" "unprognostic (7.19e-3)" "unprognostic (2.19e-3)" "unprognostic (1.04e-2)" "unprognostic (3.27e-2)" "unprognostic (1.38e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (9.24e-2)" "potential prognostic favorable (3.33e-4)" "unprognostic (1.39e-2)" "unprognostic (8.07e-2)" "unprognostic (2.38e-3)" "unprognostic (7.41e-2)" "unprognostic (1.10e-2)" "unprognostic (3.71e-1)" KLF11 "FKLF, MODY7, TIEG2, Tieg3" ENSG00000172059 "KLF transcription factor 11" O14901 2 10042849-10054836 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 188.3;Suprabasal keratinocytes: 73.5" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 188.3" "Cell type enhanced" "Detected in many" "endothelial cell: 32.4;pericyte: 22.2;vascular associated smooth muscle cell: 24.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 581 "B-cells: 105511.1;Hepatocytes: 30469.0;T-cells: 38198.6" "Not detected" "Not detected" HPA058276 Supported "Nucleoplasm,Nuclear bodies,Focal adhesion sites,Cytosol" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 167 Nucleoplasm "Nuclear bodies, Focal adhesion sites, Cytosol" "HPA058276: " "unprognostic (1.10e-2)" "unprognostic (5.54e-3)" "unprognostic (7.76e-3)" "unprognostic (3.31e-1)" "unprognostic (1.90e-1)" "unprognostic (3.24e-2)" "unprognostic (3.24e-3)" "unprognostic (2.29e-2)" "unprognostic (2.79e-3)" "unprognostic (1.56e-1)" "potential prognostic favorable (2.81e-7)" "unprognostic (4.56e-2)" "unprognostic (3.94e-1)" "unprognostic (1.13e-2)" "unprognostic (3.76e-1)" "unprognostic (9.97e-2)" "unprognostic (1.62e-1)" "unprognostic (8.60e-2)" "unprognostic (4.42e-2)" "unprognostic (7.37e-2)" "unprognostic (2.95e-1)" "unprognostic (3.28e-3)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (1.24e-1)" "unprognostic (1.05e-2)" "unprognostic (2.04e-1)" "unprognostic (2.21e-1)" "unprognostic (4.09e-1)" "unprognostic (4.18e-3)" "unprognostic (2.66e-2)" KLF2 LKLF ENSG00000127528 "KLF transcription factor 2" Q9Y5W3 19 16324826-16328685 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 765.7;Foveolar cells: 532.3;Innate lymphoid cells: 408.3;Lymphatic endothelial cells: 534.2;Monocyte progenitors: 384.4;Myosatellite cells: 395.2;Neutrophils: 1079.9;NK-cells: 428.9;Plasma cells: 683.2;Smooth muscle cells: 627.9;Vascular endothelial cells: 636.1;Vascular smooth muscle cells: 652.5" "Cell type enhanced" "Detected in all" "B-cells: 765.7;Neutrophils: 1079.9" "Cell type enhanced" "Detected in many" "endothelial cell: 567.9;leukocyte: 174.5;vascular associated smooth muscle cell: 227.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Myeloma: 61.1" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1170 "B-cells: 55991.8;T-cells: 178090.7" "Tissue enriched" "Detected in single" 1388 "lymphoid tissue: 138790.1" "HPA055964, HPA076411" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 11 Nucleoplasm Cytosol "HPA055964: , HPA076411: " "unprognostic (2.15e-1)" "unprognostic (1.02e-2)" "unprognostic (2.81e-3)" "unprognostic (1.17e-1)" "unprognostic (7.76e-3)" "unprognostic (4.68e-2)" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (5.36e-4)" "unprognostic (6.64e-2)" "validated prognostic favorable (4.14e-8)" "validated prognostic favorable (1.25e-4)" "unprognostic (8.97e-3)" "validated prognostic favorable (1.23e-6)" "validated prognostic favorable (5.01e-5)" "unprognostic (2.57e-3)" "unprognostic (4.28e-3)" "unprognostic (2.59e-2)" "unprognostic (2.16e-1)" "unprognostic (4.19e-2)" "unprognostic (2.90e-3)" "unprognostic (3.68e-1)" "unprognostic (3.76e-3)" "unprognostic (2.25e-1)" "unprognostic (3.32e-1)" "unprognostic (5.82e-3)" "unprognostic (8.09e-2)" "unprognostic (1.36e-1)" "unprognostic (2.27e-2)" "unprognostic (1.41e-1)" "unprognostic (6.32e-2)" KLF4 "EZF, GKLF" ENSG00000136826 "KLF transcription factor 4" O43474 9 107484852-107490482 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 185.8" "Cell type enhanced" "Detected in many" "Breast secretory cells: 465.6;Colonocytes: 645.1;Esophageal apical cells: 600.4;Goblet cells: 916.9;Ocular epithelial cells: 494.6;Suprabasal keratinocytes: 583.4" "Cell type enhanced" "Detected in many" "Goblet cells: 916.9" "Cell type enhanced" "Detected in some" "endothelial cell: 101.2;fibroblast: 36.6;vascular associated smooth muscle cell: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.0;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 65 "lymphoid tissue: 6477.8" HPA002926 Enhanced Approved Nucleoplasm,Microtubules,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 58: Skin - Keratinization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 70: Intestinal goblet cells - Mucin production" 31 Nucleoplasm "Microtubules, Cytosol" "HPA002926: " "unprognostic (2.55e-2)" "unprognostic (1.72e-1)" "unprognostic (2.56e-2)" "unprognostic (1.99e-2)" "unprognostic (5.12e-3)" "unprognostic (1.06e-1)" "unprognostic (3.31e-1)" "unprognostic (3.77e-3)" "unprognostic (2.90e-3)" "unprognostic (8.80e-2)" "validated prognostic favorable (2.11e-5)" "validated prognostic favorable (1.13e-4)" "unprognostic (1.07e-2)" "unprognostic (4.46e-2)" "unprognostic (4.96e-2)" "unprognostic (3.16e-3)" "unprognostic (5.82e-2)" "unprognostic (1.59e-1)" "unprognostic (2.54e-1)" "unprognostic (8.49e-2)" "unprognostic (4.23e-2)" "unprognostic (1.42e-3)" "unprognostic (2.50e-1)" "unprognostic (1.36e-1)" "unprognostic (1.42e-1)" "unprognostic (1.35e-1)" "unprognostic (3.17e-1)" "unprognostic (2.87e-1)" "unprognostic (2.26e-1)" "unprognostic (1.20e-1)" "unprognostic (2.99e-2)" KLF6 "BCD1, COPEB, CPBP, GBF, PAC1, ST12, Zf9" ENSG00000067082 "KLF transcription factor 6" Q99612 10 3775996-3785281 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 412.7" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 2246.3;Epididymal basal cells: 2752.0;Epididymal efferent duct absorptive cells: 2778.8" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "endothelial cell: 296.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013529, HPA069585" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Vesicles,Cytosol" No No "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 Nucleoplasm "Nucleoli, Nucleoli fibrillar center, Vesicles, Cytosol" "CAB013529: , HPA069585: " "unprognostic (7.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.47e-3)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (3.54e-3)" "unprognostic (2.30e-1)" "unprognostic (1.18e-1)" "unprognostic (2.98e-2)" "unprognostic (1.62e-1)" "unprognostic (3.42e-2)" "potential prognostic favorable (2.14e-7)" "unprognostic (1.77e-3)" "unprognostic (3.83e-2)" "unprognostic (1.40e-1)" "unprognostic (1.30e-1)" "unprognostic (2.83e-1)" "unprognostic (5.03e-2)" "unprognostic (1.70e-3)" "unprognostic (2.97e-2)" "unprognostic (7.75e-3)" "unprognostic (3.92e-1)" "unprognostic (1.03e-2)" "unprognostic (4.13e-3)" "unprognostic (3.76e-2)" "unprognostic (1.72e-2)" "potential prognostic favorable (8.17e-4)" "unprognostic (1.51e-1)" "unprognostic (4.97e-3)" "unprognostic (7.44e-2)" "unprognostic (6.79e-2)" "unprognostic (5.97e-2)" KLHDC1 MST025 ENSG00000197776 "Kelch domain containing 1" Q8N7A1 14 49693105-49753150 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 205.6" "Cell type enhanced" "Detected in many" "Myocytes: 205.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 3030 "intestine: 303049.5" HPA020461 Approved Supported Cytosol No No "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 7: Non-specific - Transcription" Cytosol "HPA020461: " "unprognostic (3.94e-1)" "unprognostic (1.07e-1)" "unprognostic (2.49e-1)" "unprognostic (2.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.46e-1)" "unprognostic (3.78e-3)" "potential prognostic favorable (1.37e-4)" "unprognostic (1.10e-2)" "unprognostic (1.42e-3)" "unprognostic (8.65e-3)" "unprognostic (6.21e-2)" "unprognostic (4.43e-2)" "unprognostic (1.80e-1)" "potential prognostic favorable (6.32e-4)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (3.58e-2)" "unprognostic (5.92e-2)" "unprognostic (1.04e-1)" "unprognostic (4.96e-2)" KLHDC8B MGC35097 ENSG00000185909 "Kelch domain containing 8B" Q8IXV7 3 49171598-49176486 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 123.7" "Cell type enriched" "Detected in many" 4 "Platelets: 388.1" "Cell type enriched" "Detected in many" 4 "Platelets: 388.1" "Cell type enhanced" "Detected in many" "pericyte: 54.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 28.8" "Group enriched" "Detected in many" 10 "granulocytes: 28.8;monocytes: 8.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 1560865.6;Oocytes: 1210897.5" "Not detected" "Not detected" "HPA008463, HPA014467" Approved Enhanced Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 3 Cytosol "HPA008463: , HPA014467: " "unprognostic (2.34e-1)" "unprognostic (1.03e-1)" "unprognostic (2.39e-1)" "unprognostic (1.66e-1)" "unprognostic (6.49e-3)" "unprognostic (2.84e-1)" "unprognostic (7.03e-2)" "unprognostic (2.40e-2)" "unprognostic (2.59e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (1.36e-7)" "unprognostic (6.44e-3)" "potential prognostic favorable (6.76e-4)" "potential prognostic unfavorable (9.41e-4)" "unprognostic (5.59e-2)" "unprognostic (1.56e-3)" "unprognostic (2.82e-1)" "unprognostic (2.15e-2)" "unprognostic (1.35e-1)" "unprognostic (7.96e-2)" "unprognostic (1.42e-1)" "unprognostic (2.32e-2)" "unprognostic (2.58e-1)" "unprognostic (3.15e-2)" "unprognostic (3.00e-2)" "unprognostic (1.67e-1)" "unprognostic (3.60e-2)" "unprognostic (1.64e-2)" "unprognostic (1.73e-1)" "unprognostic (2.48e-2)" "unprognostic (6.51e-2)" KLHDC9 KARCA1 ENSG00000162755 "Kelch domain containing 9" Q8NEP7 1 161098361-161100346 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 24.6" "Group enriched" "Detected in many" 4 "Early spermatids: 381.9;Late primary spermatocytes: 473.0;Late spermatids: 589.9" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 589.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Oocytes: 1389283.3" "Tissue enriched" "Detected in single" 6514 "cerebral cortex: 651381.9" HPA043197 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes NA "Cluster 79: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "Nucleoplasm, Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA043197: " "unprognostic (2.24e-1)" "unprognostic (1.44e-1)" "unprognostic (1.52e-2)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (1.95e-2)" "unprognostic (1.09e-2)" "unprognostic (9.28e-2)" "unprognostic (4.70e-2)" "potential prognostic favorable (3.71e-4)" "unprognostic (8.04e-3)" "unprognostic (4.91e-1)" "unprognostic (2.53e-2)" "unprognostic (1.32e-1)" "unprognostic (2.75e-3)" "unprognostic (7.24e-2)" KLHL11 FLJ10572 ENSG00000178502 "Kelch like family member 11" Q9NVR0 17 41848518-41865423 "Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 158.2;Late spermatids: 58.6;Retinal horizontal cells: 34.1" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 158.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 145532.0" "Not detected" "Not detected" "HPA023021, HPA052403, HPA054269" Uncertain Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 5 Nucleoplasm "Nuclear membrane" "HPA023021: , HPA052403: , HPA054269: " "unprognostic (1.46e-1)" "unprognostic (1.41e-2)" "unprognostic (1.67e-1)" "unprognostic (6.06e-2)" "unprognostic (7.46e-2)" "unprognostic (6.45e-3)" "unprognostic (2.68e-1)" "unprognostic (5.82e-3)" "unprognostic (6.87e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (8.45e-3)" "unprognostic (2.15e-1)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.42e-1)" "unprognostic (2.63e-1)" "unprognostic (2.01e-1)" "potential prognostic favorable (1.57e-4)" "unprognostic (1.26e-2)" "unprognostic (4.99e-3)" "unprognostic (1.87e-1)" "unprognostic (1.27e-1)" "unprognostic (6.97e-3)" "unprognostic (1.67e-2)" "unprognostic (4.87e-2)" "unprognostic (1.84e-1)" "unprognostic (4.88e-2)" "unprognostic (2.49e-2)" "unprognostic (3.77e-1)" KLHL22 "FLJ14360, KELCHL" ENSG00000099910 "Kelch like family member 22" Q53GT1 22 20441519-20495844 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 106.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 18574069.0" "Low tissue specificity" "Detected in many" HPA040766 Supported "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 70 "Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA040766: " "unprognostic (3.48e-3)" "unprognostic (3.13e-1)" "unprognostic (1.67e-1)" "unprognostic (3.18e-1)" "unprognostic (6.09e-2)" "unprognostic (1.31e-1)" "unprognostic (4.36e-1)" "unprognostic (1.08e-2)" "unprognostic (4.30e-3)" "unprognostic (7.45e-2)" "potential prognostic favorable (2.30e-6)" "unprognostic (6.57e-3)" "potential prognostic favorable (1.46e-5)" "unprognostic (4.14e-2)" "unprognostic (8.63e-2)" "unprognostic (2.86e-1)" "unprognostic (6.92e-2)" "unprognostic (1.29e-1)" "unprognostic (2.35e-2)" "unprognostic (2.10e-1)" "unprognostic (5.27e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (3.86e-2)" "unprognostic (2.19e-2)" "unprognostic (1.57e-1)" "unprognostic (3.19e-1)" "unprognostic (2.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.64e-1)" "unprognostic (4.11e-2)" "unprognostic (4.68e-2)" KLHL38 C8ORFK36 ENSG00000175946 "Kelch like family member 38" Q2WGJ6 8 123644442-123653801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 50.8;skeletal muscle: 238.4;tongue: 66.4" "Group enriched" "Detected in some" 16 "Cardiomyocytes: 44.1;Myonuclei: 25.9;Thymic myoid cells: 21.8" "Group enriched" "Detected in some" 17 "Myocytes: 44.1;Stromal cells: 21.8" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Breast Invasive Carcinoma (TCGA): 1.8;Skin Cutaneous Melanoma (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024770, HPA027115" Uncertain Approved Nucleoplasm,Cytosol Yes NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 72 Nucleoplasm Cytosol "HPA024770: , HPA027115: " "unprognostic (5.99e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-1)" KLHL4 "DKELCHL, KHL4, KIAA1687" ENSG00000102271 "Kelch like family member 4" Q9C0H6 X 87517409-87670050 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.1;brain: 9.6;ovary: 9.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 366.9;Cone photoreceptor cells: 93.2;Lymphatic endothelial cells: 234.8;Mesothelial cells: 105.3;Oligodendrocyte progenitor cells: 75.9;Oligodendrocytes: 325.6;Ovarian stromal cells: 58.6;Sertoli cells: 405.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 366.9;Endothelial cells: 234.8;Glial cells: 325.6;Reproductive supporting cells: 405.5" "Cell type enhanced" "Detected in many" "oligodendrocyte: 441.8" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 16.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 16.4" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" "fallopian tube: 521105.8;ovary: 315456.1" HPA029192 Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Centrosome,Basal body" Yes NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Centrosome, Basal body" "HPA029192: " "unprognostic (3.51e-2)" "unprognostic (1.13e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-3)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (4.96e-2)" "unprognostic (3.33e-1)" "unprognostic (4.59e-3)" "unprognostic (2.65e-3)" KLHL41 "KBTBD10, Krp1, SARCOSIN" ENSG00000239474 "Kelch like family member 41" O60662 2 169509702-169526258 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 42 "skeletal muscle: 4718.5;tongue: 3245.2" "Cell type enriched" "Detected in some" 7 "Thymic myoid cells: 492.2" "Cell type enriched" "Detected in some" 7 "Stromal cells: 492.2" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 8 "Head and Neck Squamous Cell Carcinoma (TCGA): 27.1;Prostate Adenocarcinoma (TCGA): 7.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Sarcoma: 16.3" "Pituitary gland - Gonadotropes, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Skeletal myofibers: 734600053.7" "Tissue enriched" "Detected in some" "skeletal muscle: 180137070.7" "HPA021165, HPA021753, HPA021760" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 12000 "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 10 Cytosol "Nucleoplasm, Plasma membrane" "HPA021165: , HPA021753: , HPA021760: " "unprognostic (1.07e-1)" "unprognostic (3.06e-1)" "unprognostic (4.00e-3)" "potential prognostic favorable (3.34e-4)" "unprognostic (2.49e-1)" "unprognostic (2.66e-1)" "unprognostic (1.65e-3)" KLHL6 FLJ00029 ENSG00000172578 "Kelch like family member 6" Q8WZ60 3 183487551-183555706 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "lymphoid tissue: 29.1" "Cell type enhanced" "Detected in many" "B-cells: 134.0;cDC: 126.9;Hematopoietic stem cells: 83.5;Innate lymphoid cells: 109.4;Kupffer cells: 59.4;Macrophages: 134.5;Mast cells: 74.6;Microglia: 69.6;monocytes: 92.9;Neutrophils: 63.9;NK-cells: 61.0;pDCs: 78.2;Plasma cells: 284.5;Platelets: 168.1;Respiratory ciliated cells: 90.2;Thymocytes: 87.2" "Cell type enhanced" "Detected in many" "B-cells: 134.0;dendritic cells: 126.9;Mononuclear phagocytes: 134.5;Plasma cells: 284.5;Platelets: 168.1" "Group enriched" "Detected in some" 9 "central nervous system macrophage: 95.1;leukocyte: 48.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 78 "Leukemia: 13.6;lymphoma: 35.9;Myeloma: 27.1" "Adipose visceral - T-cells, Minor Salivary Gland - Plasma cells, Prostate - T-cells, Spleen - B-cells (Spleen), Stomach - Plasma cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 220374.7;Neutrophils: 221538.7" "Tissue enriched" "Detected in single" 14147 "lymphoid tissue: 1414724.6" HPA024512 Uncertain Approved "Plasma membrane,Microtubules,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 12 "Plasma membrane, Centriolar satellite" "Microtubules, Mitotic spindle, Cytosol" "HPA024512: " "unprognostic (4.66e-2)" "unprognostic (6.01e-2)" "unprognostic (2.23e-1)" "unprognostic (5.14e-3)" "unprognostic (2.41e-1)" "unprognostic (7.30e-2)" "unprognostic (7.59e-2)" "unprognostic (5.97e-1)" "potential prognostic favorable (3.13e-4)" "unprognostic (1.13e-1)" "unprognostic (2.60e-2)" "unprognostic (1.97e-1)" "unprognostic (2.24e-2)" "potential prognostic favorable (3.80e-4)" "unprognostic (7.88e-2)" "unprognostic (5.34e-2)" "unprognostic (3.49e-1)" "unprognostic (4.90e-1)" "unprognostic (5.88e-2)" "unprognostic (4.81e-2)" "unprognostic (6.24e-2)" "unprognostic (4.88e-1)" "unprognostic (3.85e-1)" "unprognostic (1.45e-1)" "unprognostic (3.06e-1)" KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 90.8;skin 1: 189.2" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 1071.4;Salivary duct cells: 306.6" "Group enriched" "Detected in some" 4 "Apical squamous epithelial cells: 1071.4;Ductal cells: 306.6" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 12.6;hippocampal CA4: 18.6;lower rhombic lip: 9.3" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 241.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Bile duct cancer: 63.9;colorectal cancer: 23.3;Gastric cancer: 17.6;head and neck cancer: 31.1;ovarian cancer: 27.9" "Adipose visceral - Mesothelial cells, Kidney - Podocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 13458 "Keratinocytes: 1345780.3" "Tissue enhanced" "Detected in all" "intestine: 15374979.3" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" Enzyme NA NA 7300000 "Cluster 58: Skin - Keratinization" "Cluster 24: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: , HPA062126: " "unprognostic (9.81e-2)" "unprognostic (2.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.19e-1)" "unprognostic (8.42e-2)" "potential prognostic favorable (1.42e-4)" "unprognostic (1.94e-1)" "unprognostic (1.29e-2)" "unprognostic (3.03e-1)" "unprognostic (1.30e-2)" "unprognostic (8.15e-2)" "unprognostic (2.55e-2)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (7.47e-5)" "unprognostic (2.27e-1)" "unprognostic (2.18e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "unprognostic (3.75e-1)" "unprognostic (1.38e-2)" "unprognostic (8.22e-2)" KLLN killin ENSG00000227268 "Killin, p53 regulated DNA replication inhibitor" B2CW77 10 87859158-87863533 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "skeletal muscle: 4.1" "Cell type enhanced" "Detected in single" "Papillary tip epithelial cells: 1.1" "Cell type enhanced" "Detected in single" "Renal nephron cells: 1.1" "Cell type enhanced" "Detected in some" "pericyte: 3.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA074502 Supported Nucleoplasm,Nucleoli No No "Cluster 20: Non-specific - DNA binding" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm Nucleoli "HPA074502: " "unprognostic (4.49e-2)" "unprognostic (8.18e-3)" "unprognostic (5.64e-2)" "unprognostic (2.58e-1)" "unprognostic (1.16e-1)" "unprognostic (2.97e-2)" "unprognostic (2.36e-1)" "unprognostic (2.09e-1)" "unprognostic (2.91e-2)" "unprognostic (5.69e-2)" "unprognostic (1.48e-1)" KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.2" "Group enriched" "Detected in some" 4 "NK-cells: 282.6;T-cells: 107.0" "Group enriched" "Detected in many" 4 "NK-cells: 282.6;T-cells: 107.0" "Cell type enriched" "Detected in some" 60 "leukocyte: 107.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "gdT-cell: 229.7;NK-cell: 368.5" "Group enriched" "Detected in many" 47 "NK-cells: 368.5;T-cells: 229.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Liver - NK-cells (Liver), Minor Salivary Gland - T-cells, Pancreas - T-cells, Prostate - T-cells, Spleen - NK-cells (Spleen), Stomach - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA058052 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 44 "Plasma membrane" "HPA058052: " "unprognostic (4.00e-2)" "unprognostic (2.80e-1)" "unprognostic (5.81e-2)" "unprognostic (5.44e-3)" "unprognostic (7.23e-2)" "unprognostic (3.31e-3)" "unprognostic (5.21e-3)" "unprognostic (3.31e-3)" "unprognostic (1.84e-1)" "unprognostic (1.03e-1)" "unprognostic (4.05e-1)" "unprognostic (6.17e-3)" "unprognostic (3.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.38e-1)" "unprognostic (5.03e-2)" "unprognostic (1.04e-1)" "unprognostic (9.46e-2)" "unprognostic (1.53e-1)" "unprognostic (3.88e-1)" KLRC2 "CD159c, NKG2-C, NKG2C" ENSG00000205809 "Killer cell lectin like receptor C2" P26717 12 10426854-10442300 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.0;lymphoid tissue: 5.1" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 3.0;NK-cells: 30.3;Oligodendrocyte progenitor cells: 49.9;Oligodendrocytes: 3.9;T-cells: 11.5" "Cell type enhanced" "Detected in some" "Glial cells: 49.9;NK-cells: 30.3;T-cells: 11.5" "Group enriched" "Detected in some" 5 "leukocyte: 49.4;oligodendrocyte precursor cell: 56.1" "Cancer enriched" "Detected in many" 10 "Glioblastoma Multiforme (TCGA): 18.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "gdT-cell: 24.7;NK-cell: 84.6" "Group enriched" "Detected in many" 103 "NK-cells: 84.6;T-cells: 24.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 16.2" "Adipose visceral - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA058052 Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 3 "Plasma membrane" "HPA058052: " "unprognostic (1.42e-1)" "unprognostic (1.81e-1)" "unprognostic (2.27e-3)" "unprognostic (7.21e-2)" "unprognostic (3.94e-1)" "unprognostic (1.63e-1)" "potential prognostic favorable (6.25e-4)" "unprognostic (1.25e-1)" "unprognostic (1.22e-1)" "unprognostic (9.02e-2)" "unprognostic (9.67e-3)" "unprognostic (5.52e-3)" "unprognostic (4.02e-1)" "potential prognostic favorable (8.59e-5)" "unprognostic (1.13e-1)" "unprognostic (2.34e-2)" KLRC3 NKG2-E ENSG00000205810 "Killer cell lectin like receptor C3" Q07444 12 10412315-10420595 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 1.8;brain: 4.7;intestine: 1.2;lymphoid tissue: 3.9" "Cell type enriched" "Detected in some" 4 "Oligodendrocyte progenitor cells: 64.0" "Cell type enriched" "Detected in some" 9 "Glial cells: 64.0" "Cell type enhanced" "Detected in some" "leukocyte: 52.4;oligodendrocyte precursor cell: 76.4" "Cancer enriched" "Detected in single" 6 "Glioblastoma Multiforme (TCGA): 4.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "NK-cell: 63.5" "Lineage enriched" "Detected in many" 6 "NK-cells: 63.5" "Cancer enhanced" "Detected in some" "lymphoma: 5.2;thyroid cancer: 5.6" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - NK-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039910, HPA062570" Approved Uncertain Vesicles NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Vesicles "HPA039910: , HPA062570: " "unprognostic (3.47e-1)" "unprognostic (8.34e-2)" "potential prognostic favorable (4.36e-4)" "unprognostic (5.42e-2)" KLRG1 "2F1, CLEC15A, MAFA, MAFA-L" ENSG00000139187 "Killer cell lectin like receptor G1" Q96E93 12 8950044-9010760 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 45.4;Mast cells: 135.4;Myonuclei: 56.6;NK-cells: 72.4;T-cells: 98.3" "Cell type enhanced" "Detected in many" "Mast cells: 135.4;NK-cells: 72.4;T-cells: 98.3" "Cell type enhanced" "Detected in all" "leukocyte: 109.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "gdT-cell: 391.8;MAIT T-cell: 462.2" "Lineage enriched" "Detected in all" 22 "T-cells: 462.2" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts, Spleen - T-cells, Stomach - Fibroblasts, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051403, HPA076494" Approved Enhanced Vesicles NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 9 Vesicles "HPA051403: , HPA076494: " "unprognostic (1.71e-1)" "unprognostic (8.72e-2)" "unprognostic (1.54e-2)" "unprognostic (1.98e-2)" "unprognostic (1.85e-1)" "unprognostic (6.42e-3)" "unprognostic (5.37e-2)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.30e-5)" "unprognostic (1.20e-1)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (8.78e-2)" "unprognostic (5.07e-1)" "unprognostic (3.02e-3)" "unprognostic (6.36e-2)" "unprognostic (5.97e-2)" "unprognostic (5.75e-3)" "unprognostic (1.39e-1)" "unprognostic (2.22e-1)" "unprognostic (1.03e-1)" "unprognostic (1.72e-2)" KMT2C "HALR, KIAA1506, MLL3" ENSG00000055609 "Lysine methyltransferase 2C" Q8NEZ4 7 152134922-152436644 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Acyltransferase, Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1797.6" "Cell type enhanced" "Detected in all" "Neutrophils: 1797.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 535622.0;Fallopian tube cells: 325996.9" "Low tissue specificity" "Detected in many" "HPA062814, HPA074736" Enhanced Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 39: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 34 Nucleoplasm Cytosol "HPA062814: , HPA074736: " "unprognostic (4.41e-2)" "unprognostic (5.97e-2)" "unprognostic (1.74e-1)" "unprognostic (9.00e-2)" "unprognostic (5.25e-2)" "unprognostic (2.91e-1)" "unprognostic (1.01e-1)" "unprognostic (9.48e-3)" "unprognostic (7.98e-2)" "potential prognostic favorable (1.62e-6)" "unprognostic (2.75e-3)" "unprognostic (2.35e-1)" "unprognostic (1.89e-1)" "unprognostic (1.69e-2)" "unprognostic (2.04e-1)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (1.95e-1)" "unprognostic (2.32e-1)" "unprognostic (1.72e-1)" "unprognostic (4.90e-2)" "unprognostic (2.75e-1)" "unprognostic (3.22e-2)" "unprognostic (1.77e-2)" "unprognostic (9.91e-2)" "unprognostic (2.35e-1)" "unprognostic (3.67e-1)" "unprognostic (9.95e-3)" "unprognostic (9.79e-2)" KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018975-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Congenital hypothyroidism, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 88.6" "Cell type enhanced" "Detected in many" "Neutrophils: 88.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 2626467.2" "Tissue enhanced" "Detected in many" "lymphoid tissue: 910825.3" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 39 "Plasma membrane, Cytosol" Nucleoplasm "HPA035977: " "unprognostic (5.28e-2)" "unprognostic (1.03e-1)" "unprognostic (7.45e-3)" "unprognostic (6.54e-2)" "unprognostic (1.11e-1)" "unprognostic (7.03e-2)" "unprognostic (1.78e-1)" "unprognostic (1.34e-1)" "unprognostic (7.31e-2)" "unprognostic (1.77e-2)" "unprognostic (1.96e-2)" "unprognostic (7.98e-2)" "unprognostic (8.26e-3)" "unprognostic (1.86e-1)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.81e-3)" "unprognostic (9.90e-2)" "unprognostic (1.79e-1)" "unprognostic (3.29e-2)" "unprognostic (2.21e-2)" "unprognostic (4.77e-3)" "unprognostic (1.56e-1)" "unprognostic (8.17e-3)" "unprognostic (1.61e-1)" "unprognostic (2.27e-1)" "unprognostic (9.95e-2)" "unprognostic (7.85e-2)" "unprognostic (1.26e-1)" KMT2E "HDCMC04P, MLL5, SETD5B" ENSG00000005483 "Lysine methyltransferase 2E (inactive)" Q8IZD2 7 104940943-105115019 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Growth arrest, Transcription, Transcription regulation" "Chromatin regulator" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1496.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 196919.9" "Not detected" "Not detected" "HPA042866, HPA056125" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 40: Non-specific - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 5 Nucleoplasm "Nuclear bodies, Cytosol" "HPA042866: , HPA056125: " "potential prognostic favorable (7.96e-4)" "unprognostic (2.13e-1)" "unprognostic (8.44e-3)" "unprognostic (1.00e-1)" "unprognostic (1.19e-2)" "unprognostic (2.94e-1)" "unprognostic (1.17e-1)" "unprognostic (8.17e-2)" "unprognostic (3.50e-3)" "validated prognostic favorable (3.55e-5)" "validated prognostic favorable (5.22e-4)" "unprognostic (3.73e-2)" "unprognostic (8.57e-2)" "unprognostic (6.64e-2)" "unprognostic (9.94e-2)" "unprognostic (1.41e-2)" "unprognostic (1.07e-1)" "unprognostic (1.78e-3)" "unprognostic (1.69e-1)" "unprognostic (2.16e-2)" "unprognostic (2.53e-2)" "unprognostic (1.36e-1)" "unprognostic (1.97e-1)" "unprognostic (1.38e-2)" "unprognostic (2.48e-2)" "unprognostic (1.00e-1)" "unprognostic (1.67e-1)" "unprognostic (3.19e-2)" "unprognostic (1.74e-1)" KMT5A "PR-Set7, SET07, SET8, SETD8" ENSG00000183955 "Lysine methyltransferase 5A" Q9NQR1 12 123384132-123409353 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 136.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "pancreas: 531063.0" HPA064495 Supported Nucleoplasm,Cytosol NA Yes "Cluster 32: Basophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 33 Nucleoplasm Cytosol "HPA064495: " "unprognostic (1.52e-2)" "unprognostic (1.84e-1)" "unprognostic (2.10e-2)" "unprognostic (2.58e-1)" "unprognostic (1.40e-3)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (2.08e-1)" "unprognostic (1.27e-1)" "unprognostic (2.77e-3)" "unprognostic (1.33e-2)" "unprognostic (5.60e-2)" "potential prognostic unfavorable (1.99e-8)" "potential prognostic unfavorable (6.56e-4)" "unprognostic (1.69e-2)" "unprognostic (2.20e-2)" "unprognostic (5.97e-2)" "unprognostic (2.84e-2)" "unprognostic (2.17e-2)" "unprognostic (8.50e-2)" "unprognostic (2.68e-2)" "unprognostic (3.65e-1)" "unprognostic (2.00e-1)" "unprognostic (2.00e-2)" "unprognostic (6.01e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (4.40e-2)" "unprognostic (9.21e-2)" KMT5B "CGI-85, SUV420H1" ENSG00000110066 "Lysine methyltransferase 5B" Q4FZB7 11 68154863-68213852 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 66 "Collecting ducts: 9846.2;Fallopian tube cells: 3339.4" "Not detected" "Not detected" HPA038509 Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centrosome,Basal body,Cytoplasmic bodies" Yes NA "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 4 "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane, Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium, Centrosome, Basal body, Cytoplasmic bodies" "HPA038509: " "unprognostic (1.14e-1)" "unprognostic (3.70e-2)" "unprognostic (2.36e-3)" "unprognostic (2.27e-1)" "unprognostic (6.98e-3)" "unprognostic (4.75e-1)" "unprognostic (1.20e-2)" "unprognostic (6.20e-2)" "unprognostic (2.31e-1)" "potential prognostic favorable (3.27e-4)" "unprognostic (2.69e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (2.13e-2)" "unprognostic (2.00e-3)" "unprognostic (5.41e-2)" "unprognostic (3.73e-1)" "unprognostic (2.65e-1)" "unprognostic (1.31e-2)" "unprognostic (6.81e-3)" "potential prognostic unfavorable (6.17e-4)" "unprognostic (3.88e-2)" "unprognostic (7.03e-2)" "unprognostic (5.54e-2)" "unprognostic (1.65e-1)" "unprognostic (4.02e-1)" "unprognostic (4.20e-1)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" KNL1 "AF15Q14, CASC5, CT29, D40, hKNL-1, hSpc105, KIAA1570, MCPH4, PPP1R55, Spc7" ENSG00000137812 "Kinetochore scaffold 1" Q8NG31 15 40594020-40664342 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Cancer-related genes, Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 4.9;lymphoid tissue: 6.9;testis: 15.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 203.3;Early primary spermatocytes: 498.2;Erythrocyte progenitors: 141.6;Late primary spermatocytes: 92.9;Megakaryocyte progenitors: 120.0;Monocyte progenitors: 210.6;Neutrophil progenitors: 124.9;Undifferentiated spermatogonia: 87.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 141.6;Megakaryocytes: 120.0;Mononuclear phagocytes: 210.6;Neutrophils: 124.9;Spermatogenic cell types: 498.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 7.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Liver - Hepatocytes, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in some" "Oocytes: 1137984.8" "Not detected" "Not detected" "HPA026624, HPA049647" Enhanced Supported "Nucleoplasm,Nuclear bodies" Yes Yes "Cluster 39: Testis - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 30 Nucleoplasm "Nuclear bodies" "HPA026624: , HPA049647: " "unprognostic (2.31e-2)" "unprognostic (8.58e-2)" "unprognostic (2.45e-2)" "unprognostic (3.27e-1)" "unprognostic (2.55e-1)" "unprognostic (8.79e-3)" "unprognostic (2.78e-2)" "validated prognostic unfavorable (1.94e-4)" "validated prognostic unfavorable (1.86e-4)" "unprognostic (1.06e-1)" "unprognostic (8.52e-2)" "unprognostic (2.30e-1)" "unprognostic (1.60e-2)" "unprognostic (4.11e-3)" "unprognostic (1.17e-1)" "unprognostic (3.57e-1)" "unprognostic (4.94e-2)" "unprognostic (4.80e-1)" "unprognostic (1.59e-1)" KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394288 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 59.0;thyroid gland: 51.2" "Group enriched" "Detected in many" 11 "Early spermatids: 405.3;Late primary spermatocytes: 260.5;Late spermatids: 939.6" "Cell type enriched" "Detected in many" 19 "Spermatogenic cell types: 939.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1501 "Granulosa cells: 150059.2" "Tissue enriched" "Detected in single" 5158 "bone marrow: 515819.6" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 40: Monocytes - Innate immune response" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 40 "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: " "unprognostic (2.57e-3)" "unprognostic (8.13e-3)" "unprognostic (6.90e-2)" "unprognostic (1.94e-1)" "unprognostic (1.87e-1)" "unprognostic (6.45e-2)" "unprognostic (1.07e-2)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (1.47e-3)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.35e-3)" "potential prognostic unfavorable (1.88e-4)" "validated prognostic unfavorable (2.28e-7)" "validated prognostic unfavorable (6.92e-4)" "unprognostic (4.11e-2)" "unprognostic (2.39e-2)" "unprognostic (1.09e-1)" "unprognostic (2.38e-2)" "validated prognostic unfavorable (7.28e-6)" "validated prognostic unfavorable (4.08e-4)" "unprognostic (1.40e-1)" "unprognostic (6.59e-2)" "unprognostic (1.13e-1)" "unprognostic (5.40e-3)" "unprognostic (4.10e-1)" "unprognostic (2.97e-1)" "unprognostic (2.36e-1)" "unprognostic (3.55e-2)" KPNA2 "IPOA1, PTAC58, QIP2, RCH1, SRP1alpha" ENSG00000182481 "Karyopherin subunit alpha 2" P52292 17 68035636-68047364 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 195.6" "Cell type enhanced" "Detected in all" "Early spermatids: 805.7;Extravillous trophoblasts: 357.8;Late primary spermatocytes: 1344.4;Late spermatids: 324.4;Oocytes: 534.2" "Cell type enhanced" "Detected in all" "Oocytes: 534.2;Spermatogenic cell types: 1344.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 7810773.2" "Tissue enhanced" "Detected in many" "blood vessel: 2975022.7;bone marrow: 3145217.7" "CAB015460, HPA041270" Enhanced Supported Nucleoplasm,Cytosol Yes Yes 170000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 203 Nucleoplasm Cytosol "CAB015460: , HPA041270: " "potential prognostic unfavorable (2.46e-4)" "unprognostic (7.03e-2)" "unprognostic (3.62e-2)" "unprognostic (3.04e-3)" "potential prognostic favorable (5.31e-4)" "unprognostic (1.89e-1)" "unprognostic (3.16e-1)" "unprognostic (2.58e-1)" "unprognostic (6.36e-3)" "unprognostic (2.64e-3)" "unprognostic (3.18e-3)" "potential prognostic unfavorable (3.93e-6)" "potential prognostic unfavorable (2.74e-5)" "validated prognostic unfavorable (1.53e-10)" "validated prognostic unfavorable (8.25e-8)" "potential prognostic unfavorable (5.62e-5)" "unprognostic (1.18e-3)" "unprognostic (6.14e-2)" "unprognostic (4.35e-2)" "unprognostic (4.04e-2)" "unprognostic (4.07e-2)" "potential prognostic unfavorable (2.68e-4)" "unprognostic (2.84e-2)" "unprognostic (6.26e-2)" "unprognostic (7.32e-2)" "unprognostic (1.46e-2)" "unprognostic (1.76e-1)" "unprognostic (6.70e-2)" "unprognostic (5.05e-2)" "unprognostic (8.12e-2)" "unprognostic (1.07e-1)" KPNB1 "IMB1, Impnb, IPO1, IPOB, MGC2155, MGC2156, MGC2157, NTF97" ENSG00000108424 "Karyopherin subunit beta 1" Q14974 17 47649476-47685505 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 523.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA029878, CAB034449, HPA050302" Supported Enhanced "Nucleoplasm,Nuclear membrane,Cytosol" Yes No 3400000 "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 237 "Nuclear membrane" "Nucleoplasm, Cytosol" "CAB034449: , HPA029878: , HPA050302: " "unprognostic (5.64e-2)" "unprognostic (2.77e-2)" "unprognostic (1.73e-2)" "unprognostic (1.91e-2)" "unprognostic (8.81e-3)" "unprognostic (1.38e-1)" "unprognostic (7.79e-2)" "unprognostic (2.92e-2)" "unprognostic (8.79e-3)" "potential prognostic unfavorable (2.31e-4)" "potential prognostic favorable (6.91e-5)" "unprognostic (4.31e-2)" "unprognostic (1.62e-2)" "unprognostic (1.04e-3)" "unprognostic (1.59e-3)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (4.21e-5)" "unprognostic (1.09e-1)" "unprognostic (5.30e-2)" "unprognostic (2.89e-1)" "unprognostic (3.93e-2)" "unprognostic (5.43e-3)" "potential prognostic unfavorable (7.58e-5)" "unprognostic (1.98e-2)" "potential prognostic favorable (6.42e-4)" "unprognostic (1.17e-2)" "unprognostic (2.87e-2)" "unprognostic (1.56e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-3)" "unprognostic (6.44e-2)" KRI1 FLJ12949 ENSG00000129347 "KRI1 homolog" Q8N9T8 19 10553085-10566031 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 9951629.6" "Tissue enhanced" "Detected in many" "intestine: 648009.6" "HPA043110, HPA043574" Approved Enhanced Nucleoli Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 22 Nucleoli "HPA043110: , HPA043574: " "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (4.69e-2)" "unprognostic (4.11e-2)" "unprognostic (3.20e-3)" "unprognostic (1.11e-2)" "unprognostic (1.84e-2)" "unprognostic (1.16e-3)" "unprognostic (1.93e-3)" "potential prognostic unfavorable (1.01e-5)" "unprognostic (6.75e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-1)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (6.08e-2)" "unprognostic (1.41e-1)" "unprognostic (3.76e-3)" "unprognostic (1.57e-2)" "unprognostic (4.55e-3)" "unprognostic (7.44e-2)" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (1.98e-3)" "unprognostic (1.00e-2)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (2.62e-1)" "unprognostic (8.80e-2)" "unprognostic (9.99e-2)" "unprognostic (7.84e-2)" "unprognostic (3.02e-1)" KRR1 "HRB2, RIP-1" ENSG00000111615 "KRR1 small subunit processome component homolog" Q13601 12 75490863-75511636 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 32785559.5" "Tissue enhanced" "Detected in many" "pancreas: 1932575.5" "HPA043433, HPA051690" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 147 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA043433: , HPA051690: " "unprognostic (3.54e-2)" "unprognostic (9.71e-2)" "unprognostic (3.20e-2)" "unprognostic (2.28e-2)" "unprognostic (2.56e-1)" "unprognostic (1.62e-1)" "unprognostic (1.05e-1)" "unprognostic (1.80e-1)" "unprognostic (2.03e-2)" "unprognostic (2.22e-3)" "potential prognostic favorable (7.27e-7)" "unprognostic (1.65e-3)" "unprognostic (3.10e-1)" "unprognostic (2.43e-3)" "unprognostic (3.51e-2)" "unprognostic (4.80e-3)" "unprognostic (7.79e-3)" "unprognostic (7.70e-3)" "unprognostic (1.04e-1)" "unprognostic (2.24e-1)" "unprognostic (8.77e-3)" "unprognostic (3.84e-3)" "unprognostic (4.92e-3)" "unprognostic (5.57e-2)" "unprognostic (5.30e-2)" "unprognostic (8.21e-2)" "unprognostic (1.37e-1)" "unprognostic (9.55e-2)" "unprognostic (1.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.41e-1)" KRT13 "CK13, K13, MGC161462, MGC3781" ENSG00000171401 "Keratin 13" P13646 17 41500981-41505705 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 11736.9;esophagus: 38499.7;vagina: 12358.9" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 297830.3;Esophageal suprabasal cells: 146075.8" "Group enriched" "Detected in many" 7 "Apical squamous epithelial cells: 297830.3;Suprabasal cells: 146075.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Bladder Urothelial Carcinoma (TCGA): 1729.0;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2656.8;Head and Neck Squamous Cell Carcinoma (TCGA): 2165.1;Lung Squamous Cell Carcinoma (TCGA): 729.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "cervical cancer: 3545.3" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells" "Group enriched" "Detected in some" "Pancreas epithelial cells: 3495894.3;Smooth muscle cells: 12038475.5" "Low tissue specificity" "Detected in all" "CAB000133, HPA030877, HPA069771" Enhanced Enhanced "Intermediate filaments" NA NA 420000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 35 "Intermediate filaments" "CAB000133: , HPA030877: , HPA069771: " "unprognostic (1.01e-3)" "unprognostic (3.05e-1)" "unprognostic (3.63e-2)" "unprognostic (2.30e-1)" "unprognostic (2.77e-1)" "unprognostic (8.93e-3)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.81e-1)" "unprognostic (3.26e-1)" "unprognostic (3.02e-2)" "unprognostic (7.37e-2)" "unprognostic (9.56e-2)" "unprognostic (4.75e-3)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.57e-5)" "unprognostic (4.85e-3)" "unprognostic (4.56e-1)" "unprognostic (5.07e-2)" "unprognostic (1.21e-1)" "unprognostic (2.38e-1)" "unprognostic (7.46e-2)" "unprognostic (2.09e-1)" KRT14 "EBS3, EBS4" ENSG00000186847 "Keratin 14" P02533 17 41582279-41586895 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 6581.3" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 32869.7;Esophageal basal cells: 8944.1;Suprabasal keratinocytes: 11198.6" "Group enriched" "Detected in many" 5 "Basal cells: 32869.7;Suprabasal cells: 11198.6" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 14138.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 2098.9" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Cell type enriched" "Detected in many" "Keratinocytes: 17976047976.9" "Tissue enhanced" "Detected in all" "skin: 1237418705.0" "CAB000134, HPA000452, HPA000539, HPA023040" Enhanced Enhanced "Intermediate filaments" NA NA 1100000000 "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 39 "Intermediate filaments" "CAB000134: , HPA000452: , HPA000539: , HPA023040: " "unprognostic (1.48e-3)" "potential prognostic favorable (1.36e-4)" "unprognostic (1.96e-1)" "unprognostic (2.84e-1)" "unprognostic (3.57e-2)" "unprognostic (5.39e-2)" "unprognostic (4.11e-1)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (2.35e-1)" "unprognostic (1.86e-1)" "unprognostic (1.79e-1)" "unprognostic (1.77e-1)" "unprognostic (4.43e-3)" "unprognostic (1.32e-1)" "unprognostic (2.71e-3)" "unprognostic (2.61e-1)" "unprognostic (9.65e-2)" "unprognostic (2.43e-1)" "unprognostic (1.53e-2)" "unprognostic (6.60e-2)" KRT15 "CK15, K15, K1CO" ENSG00000171346 "Keratin 15" P19012 17 41513745-41522529 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1708.0;skin 1: 1245.8;vagina: 627.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2280.7;Basal prostatic cells: 1586.7;Breast secretory cells: 1528.1;Esophageal basal cells: 8444.0;Ocular epithelial cells: 966.0;Respiratory basal cells: 1473.1;Submucosal glandular cells: 919.1" "Cell type enriched" "Detected in many" 5 "Basal cells: 8444.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 966.5;Head and Neck Squamous Cell Carcinoma (TCGA): 610.0;Lung Squamous Cell Carcinoma (TCGA): 787.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 522.2;head and neck cancer: 469.4" "Minor Salivary Gland - Minor salivary gland basal cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "white matter: 1.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Keratinocytes: 458082386.3" "Tissue enriched" "Detected in many" "skin: 56793257.1" "HPA023910, HPA024554" Enhanced Supported "Nucleoplasm,Intermediate filaments" No No 220000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 153 "Intermediate filaments" Nucleoplasm "HPA023910: , HPA024554: " "unprognostic (1.39e-2)" "potential prognostic favorable (5.79e-4)" "unprognostic (5.50e-3)" "unprognostic (9.09e-2)" "unprognostic (2.76e-2)" "unprognostic (5.84e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (5.63e-2)" "unprognostic (1.85e-2)" "unprognostic (2.05e-1)" "unprognostic (3.12e-2)" "unprognostic (1.68e-1)" "unprognostic (1.08e-3)" "unprognostic (2.18e-3)" "unprognostic (1.37e-1)" "unprognostic (8.96e-3)" "unprognostic (7.92e-2)" "unprognostic (1.98e-1)" "unprognostic (2.38e-3)" "unprognostic (1.35e-1)" "potential prognostic favorable (1.72e-4)" "unprognostic (1.09e-1)" KRT16 NEPPK ENSG00000186832 "Keratin 16" P08779 17 41609778-41615899 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 437.0;esophagus: 1008.0;skin 1: 348.3;vagina: 476.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 2585.0;Esophageal apical cells: 5443.3;Esophageal basal cells: 1830.8;Esophageal suprabasal cells: 5797.7;Suprabasal keratinocytes: 8134.1" "Group enriched" "Detected in many" 13 "Apical squamous epithelial cells: 5443.3;Basal cells: 2585.0;Suprabasal cells: 8134.1" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 7107.0" "Group enriched" "Detected in some" 4 "cerebellum: 9.8;cerebral cortex: 2.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 107.9;head and neck cancer: 324.1" "Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Group enriched" "Detected in many" "Cardiomyocytes: 39464733.9;Keratinocytes: 62996676.1" "Low tissue specificity" "Detected in all" "CAB000136, HPA000539" Approved Approved "Intermediate filaments" NA NA 950000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 72 "Intermediate filaments" "CAB000136: , HPA000539: " "unprognostic (3.51e-1)" "unprognostic (7.89e-3)" "unprognostic (3.10e-1)" "unprognostic (8.07e-2)" "unprognostic (1.37e-1)" "unprognostic (3.85e-1)" "unprognostic (5.50e-3)" "unprognostic (8.41e-2)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (4.47e-6)" "unprognostic (3.15e-2)" "unprognostic (8.15e-2)" "unprognostic (2.95e-2)" "unprognostic (1.36e-2)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (1.50e-5)" "unprognostic (2.14e-3)" "unprognostic (7.12e-3)" "unprognostic (2.15e-1)" "unprognostic (3.15e-1)" "unprognostic (1.93e-1)" "unprognostic (3.69e-1)" "unprognostic (1.30e-1)" "unprognostic (8.63e-2)" "unprognostic (8.42e-2)" KRT17 PCHC1 ENSG00000128422 "Keratin 17" Q04695 17 41619442-41624842 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 409.9;skin 1: 953.7;urinary bladder: 590.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2277.6;Breast myoepithelial cells: 4203.0;Endometrial secretory cells: 1827.0;Epididymal basal cells: 6663.4;Esophageal apical cells: 2167.8;Esophageal basal cells: 1467.2;Esophageal suprabasal cells: 2048.6;Ocular epithelial cells: 1007.4;Respiratory basal cells: 1606.8;Salivary basal cells: 1414.2;Salivary myoepithelial cells: 1788.0;Suprabasal keratinocytes: 2631.4;Urothelial cells: 1726.6" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 2167.8;Barrier epithelial cells: 1726.6;Basal cells: 6663.4;Secretory cells: 1827.0;Secretory gland support: 4203.0;Suprabasal cells: 2631.4" "Cell type enriched" "Detected in some" 5 "deep-layer corticothalamic and 6b: 20.1" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 4447.8;Head and Neck Squamous Cell Carcinoma (TCGA): 9171.1" "Region enhanced" "Detected in many" "cerebral cortex: 11.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 2953.8;head and neck cancer: 2649.4" "Breast - Breast myoepithelial cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" "Keratinocytes: 95683275.2;Large ducts: 49959228.2" "Low tissue specificity" "Detected in all" "CAB000029, HPA000452, HPA000453, HPA000539, HPA045062" Enhanced Enhanced "Intermediate filaments" Yes No 380000000 "Cluster 58: Skin - Keratinization" "Cluster 53: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 26 "Intermediate filaments" "CAB000029: , HPA000452: , HPA000453: , HPA000539: , HPA045062: " "unprognostic (4.86e-2)" "potential prognostic favorable (3.36e-4)" "unprognostic (3.67e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (9.90e-2)" "potential prognostic unfavorable (5.58e-5)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (5.19e-6)" "unprognostic (5.08e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (7.57e-4)" "unprognostic (8.79e-2)" "unprognostic (4.92e-3)" "unprognostic (7.70e-2)" "unprognostic (1.31e-1)" "unprognostic (1.15e-1)" "unprognostic (7.92e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-3)" "potential prognostic unfavorable (6.71e-4)" "unprognostic (7.81e-2)" "unprognostic (8.23e-3)" "unprognostic (3.44e-2)" "unprognostic (1.97e-1)" "unprognostic (1.83e-1)" "unprognostic (1.22e-2)" "unprognostic (3.35e-1)" "unprognostic (3.38e-3)" KRT19 "CK19, K19, K1CS, MGC15366" ENSG00000171345 "Keratin 19" P08727 17 41523617-41528308 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 857.0;intestine: 737.0;salivary gland: 772.3;urinary bladder: 729.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 3796.0;Colonocytes: 5383.5;Conjunctival goblet cells: 4806.7;Enterocytes: 7897.8;Esophageal apical cells: 8716.3;Extravillous trophoblasts: 10172.3;Migrating cytotrophoblasts: 4269.9;Respiratory basal cells: 5118.0;Respiratory deuterosomal cells: 3589.8;Respiratory secretory cells: 8050.2;Salivary duct cells: 4002.9;Submucosal glandular cells: 4482.7;Urothelial cells: 5849.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 8716.3;Enterocytes: 7897.8;Secretory cells: 8050.2;Trophoblast cells: 10172.3" "Cell type enhanced" "Detected in some" "endothelial cell: 5.4;upper rhombic lip: 10.4;vascular associated smooth muscle cell: 6.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 13.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 4070.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Skin - Eccrine sweat gland cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Region enriched" "Detected in many" 7 "spinal cord: 62.5" "Cell type enriched" "Detected in many" "Large ducts: 8369207249.3" "Tissue enhanced" "Detected in many" "lung: 1877543485.5" "CAB000031, HPA002465" Enhanced Supported "Intermediate filaments" NA NA 140000000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 124 "Intermediate filaments" "CAB000031: , HPA002465: " "unprognostic (3.95e-1)" "unprognostic (3.36e-1)" "unprognostic (4.25e-1)" "unprognostic (1.70e-1)" "unprognostic (2.03e-1)" "unprognostic (8.89e-2)" "unprognostic (1.97e-1)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (4.67e-4)" "validated prognostic unfavorable (7.42e-4)" "unprognostic (2.68e-1)" "unprognostic (1.93e-1)" "unprognostic (6.24e-2)" "unprognostic (4.19e-3)" "unprognostic (1.46e-1)" "unprognostic (2.33e-1)" "unprognostic (3.48e-1)" "unprognostic (1.79e-2)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (1.27e-1)" "unprognostic (6.11e-2)" "unprognostic (1.16e-1)" "unprognostic (8.29e-2)" "unprognostic (1.97e-1)" "unprognostic (2.48e-2)" "unprognostic (2.29e-1)" "unprognostic (3.51e-2)" "unprognostic (2.35e-1)" KRT20 "CK20, K20, MGC35423" ENSG00000171431 "Keratin 20" P35900 17 40875889-40885242 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 609.5" "Cell type enhanced" "Detected in some" "Colonocytes: 113.0;Enteric transient amplifying cells: 12.0;Enterocytes: 78.9;Foveolar cells: 12.8;Goblet cells: 24.4;Neuroendocrine cells: 20.6;Urothelial cells: 37.7" "Cell type enhanced" "Detected in some" "Barrier epithelial cells: 37.7;Enterocytes: 113.0;Enteroendocrine cells: 20.6;Goblet cells: 24.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "Bladder Urothelial Carcinoma (TCGA): 47.9;Colon Adenocarcinoma (TCGA): 112.1;Rectum Adenocarcinoma (TCGA): 136.2;Stomach Adenocarcinoma (TCGA): 46.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 41.5;colorectal cancer: 95.3;liver cancer: 50.6" "Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 3082 "Large ducts: 308208.7" "Group enriched" "Detected in many" "heart muscle: 486007902.2;intestine: 213415682.7" "CAB000032, HPA024309, HPA024684, HPA027236" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 38000000 "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 45 "Intermediate filaments, Cytosol" "CAB000032: , HPA024309: , HPA024684: , HPA027236: " "unprognostic (3.02e-1)" "unprognostic (9.94e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (5.37e-2)" "unprognostic (1.56e-2)" "unprognostic (2.06e-1)" "unprognostic (2.18e-2)" "unprognostic (1.69e-2)" "unprognostic (1.15e-1)" KRT24 "FLJ20261, MGC138169, MGC138173" ENSG00000167916 "Keratin 24" Q2M2I5 17 40697991-40703752 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "cervix: 43.7;esophagus: 167.8;lymphoid tissue: 71.5" "Group enriched" "Detected in some" 8 "Esophageal apical cells: 940.3;Ocular epithelial cells: 385.8" "Group enriched" "Detected in some" 8 "Apical squamous epithelial cells: 940.3;Barrier epithelial cells: 385.8" "Cell type enhanced" "Detected in single" "cerebellar inhibitory: 1.6" "Group enriched" "Detected in some" 19 "Bladder Urothelial Carcinoma (TCGA): 19.4;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 14.2;Head and Neck Squamous Cell Carcinoma (TCGA): 20.7;Lung Squamous Cell Carcinoma (TCGA): 6.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 316 "Rhabdoid: 170.8" "Skin - Keratinocyte (other), Stomach - Fibroblasts" "Region enriched" "Detected in single" 10 "cerebellum: 1.0" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA022978 Uncertain Approved "Intermediate filaments,Cytosol" No NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 29 "Intermediate filaments, Cytosol" "HPA022978: " "unprognostic (3.78e-1)" "unprognostic (1.32e-1)" "unprognostic (3.11e-2)" "unprognostic (2.49e-2)" "unprognostic (7.84e-1)" "unprognostic (4.99e-2)" "unprognostic (4.94e-3)" KRT31 "Ha-1, KRTHA1" ENSG00000094796 "Keratin 31" Q15323 17 41393721-41397608 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "skin 1: 257.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 7.9;Brain excitatory neurons: 5.3;Endometrial luminal cells: 3.2;Esophageal apical cells: 1.2;Esophageal suprabasal cells: 1.1;Suprabasal keratinocytes: 1.4" "Cell type enhanced" "Detected in some" "Basal cells: 7.9;Luminal cells: 3.2;Neuronal cells: 5.3" "Group enriched" "Detected in some" 5 "thalamic excitatory: 7.3;upper rhombic lip: 17.1" "Cancer enriched" "Detected in single" 8 "Lung Squamous Cell Carcinoma (TCGA): 6.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skeletal muscle - Skeletal myocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Cell type enriched" "Detected in single" 51635 "Keratinocytes: 5163496.0" "Tissue enhanced" "Detected in many" "cerebral cortex: 82521125.4" "HPA049550, HPA055194" Enhanced Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 65000000 "Cluster 9: Skin - Hair follicle development" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 324 "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA049550: , HPA055194: " "unprognostic (1.38e-2)" "unprognostic (2.73e-1)" KRT33A "Ha-3I, Krt1-3, KRTHA3A" ENSG00000006059 "Keratin 33A" O76009 17 41346092-41350828 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "skin 1: 42.6" "Group enriched" "Detected in some" 5 "Early spermatids: 1.2;Late spermatids: 1.7" "Cell type enriched" "Detected in single" 6 "Spermatogenic cell types: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055194 Supported Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 17000000 "Cluster 37: Skin - Keratinization" "Cluster 11: Neuronal - Sensory perception" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA055194: " KRT33B "Ha-3II, KRTHA3B" ENSG00000131738 "Keratin 33B" Q14525 17 41363498-41369813 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 56 "skin 1: 74.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in many" "intestine: 14706015.3;ovary: 20004915.4;skin: 28719083.4" HPA055194 Supported Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 58000000 "Cluster 9: Skin - Hair follicle development" "Cluster 64: Connective tissue cells - ECM organization" 81 "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA055194: " KRT34 "Ha-4, KRTHA4" ENSG00000131737 "Keratin 34" O76011 17 41377669-41382306 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 22 "skin 1: 64.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 7.1" "Skin - Hair cortex cells, Testis - Late spermatids" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 69501 "Distal tubules: 6950094.5" "Tissue enriched" "Detected in many" "heart muscle: 66861528.3" "HPA055194, HPA072208" Enhanced Approved "Cytosol,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 17000000 "Cluster 9: Skin - Hair follicle development" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 211 "Cytosol, Principal piece, End piece" "Equatorial segment, Mid piece" "HPA055194: , HPA072208: " "unprognostic (2.72e-2)" KRT4 "CK4, CYK4, K4" ENSG00000170477 "Keratin 4" P19013 12 52806549-52814116 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 18547.1" "Group enriched" "Detected in some" 4 "Esophageal apical cells: 74822.7;Esophageal suprabasal cells: 30263.3" "Group enriched" "Detected in many" 48 "Apical squamous epithelial cells: 74822.7;Suprabasal cells: 30263.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 230.8;Head and Neck Squamous Cell Carcinoma (TCGA): 328.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "cervical cancer: 1151.1;Gallbladder cancer: 1422.0" "Prostate - Urothelial cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 37829 "Alveolar cell types: 4320506.8;Keratinocytes: 2106341.0;Large ducts: 4921722.4" "Low tissue specificity" "Detected in many" "CAB002154, HPA034881" Enhanced Supported "Intermediate filaments" NA NA 170000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 28 "Intermediate filaments" "CAB002154: , HPA034881: " "unprognostic (4.16e-1)" "unprognostic (4.44e-1)" "unprognostic (9.03e-2)" "potential prognostic favorable (6.05e-5)" "unprognostic (9.85e-2)" "unprognostic (2.10e-1)" "unprognostic (4.62e-2)" "unprognostic (5.53e-2)" "unprognostic (6.13e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (2.49e-1)" "unprognostic (3.18e-3)" "unprognostic (6.94e-2)" "unprognostic (5.52e-2)" "unprognostic (5.70e-1)" "unprognostic (1.02e-1)" "unprognostic (8.98e-1)" "unprognostic (2.62e-1)" KRT5 "CK-5, EBS2, KRT5A" ENSG00000186081 "Keratin 5" P13647 12 52514575-52520530 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 2249.7;esophagus: 6496.3;skin 1: 5566.5;vagina: 2417.1" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 7750.0;Esophageal basal cells: 12161.5;Esophageal suprabasal cells: 8165.7;Ocular epithelial cells: 6624.3;Suprabasal keratinocytes: 3358.8" "Group enriched" "Detected in many" 6 "Barrier epithelial cells: 6624.3;Basal cells: 12161.5;Suprabasal cells: 8165.7" "Cell type enriched" "Detected in single" 24 "choroid plexus epithelial cell: 14.2" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 5619.7;Head and Neck Squamous Cell Carcinoma (TCGA): 10039.4" "Region enriched" "Detected in many" 34 "choroid plexus: 129.6" "Immune cell enriched" "Detected in single" 327 "plasmacytoid DC: 32.6" "Lineage enriched" "Detected in single" 327 "dendritic cells: 32.6" "Cancer enhanced" "Detected in many" "cervical cancer: 3091.5;Esophageal cancer: 1910.0;head and neck cancer: 3757.4" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in many" "Keratinocytes: 31122474446.3" "Low tissue specificity" "Detected in all" "CAB000027, CAB000129, HPA059479, CAB080101" Enhanced Approved "Intermediate filaments" NA NA 1300000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 35 "Intermediate filaments" "CAB000027: , CAB000129: , CAB080101: , HPA059479: " "unprognostic (4.14e-3)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.46e-1)" "unprognostic (4.11e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-2)" "unprognostic (8.76e-2)" "unprognostic (1.96e-1)" "unprognostic (2.00e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" "unprognostic (8.13e-2)" "unprognostic (2.82e-2)" "unprognostic (8.69e-2)" "unprognostic (7.89e-2)" "unprognostic (1.26e-1)" "unprognostic (2.29e-2)" "potential prognostic unfavorable (4.11e-4)" "unprognostic (1.39e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-1)" "unprognostic (8.29e-2)" "unprognostic (6.51e-2)" "unprognostic (1.15e-1)" "unprognostic (1.69e-2)" KRT6A "CK6C, CK6D, K6C, K6D, KRT6C, KRT6D" ENSG00000205420 "Keratin 6A" P02538 12 52487176-52493257 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Allergen, Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 5174.7;esophagus: 7111.4;vagina: 4763.0" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 41303.6;Esophageal suprabasal cells: 27326.1;Suprabasal keratinocytes: 10474.8" "Group enriched" "Detected in many" 5 "Apical squamous epithelial cells: 41303.6;Suprabasal cells: 27326.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 10248.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 2730.0;head and neck cancer: 1413.8" "Skin - Outer root sheath cells" "Cell type enriched" "Detected in many" "Keratinocytes: 29626730.4" "Low tissue specificity" "Detected in all" "HPA045697, HPA061168" Supported Enhanced "Intermediate filaments" NA NA 1400000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 46 "Intermediate filaments" "HPA045697: , HPA061168: " "unprognostic (1.99e-1)" "unprognostic (6.10e-3)" "unprognostic (9.62e-2)" "unprognostic (2.56e-1)" "unprognostic (2.93e-2)" "unprognostic (1.41e-2)" "unprognostic (2.30e-1)" "unprognostic (4.77e-1)" "potential prognostic unfavorable (6.90e-8)" "unprognostic (3.05e-1)" "unprognostic (2.94e-2)" "unprognostic (2.83e-2)" "unprognostic (1.72e-2)" "unprognostic (2.79e-1)" "unprognostic (1.00e-3)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (7.47e-2)" "unprognostic (1.87e-1)" "unprognostic (1.49e-1)" "unprognostic (2.44e-1)" "unprognostic (1.42e-1)" "unprognostic (8.64e-2)" "unprognostic (1.01e-1)" "unprognostic (4.98e-2)" KRT6B KRTL1 ENSG00000185479 "Keratin 6B" P04259 12 52446651-52452146 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 341.3;esophagus: 923.4;skin 1: 266.2" "Group enriched" "Detected in some" 5 "Esophageal apical cells: 6596.3;Esophageal suprabasal cells: 6596.2" "Group enriched" "Detected in many" 10 "Apical squamous epithelial cells: 6596.3;Suprabasal cells: 6596.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 3497.7;Skin Cutaneous Melanoma (TCGA): 934.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 104.9" "Skin - Outer root sheath cells" "Cell type enriched" "Detected in many" "Keratinocytes: 10058846.8" "Low tissue specificity" "Detected in all" "CAB000130, HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA 1600000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 30 "Intermediate filaments" "CAB000130: , HPA045697: , HPA061168: " "unprognostic (1.61e-1)" "unprognostic (2.67e-3)" "unprognostic (2.80e-1)" "unprognostic (1.62e-1)" "unprognostic (1.77e-1)" "unprognostic (1.55e-1)" "unprognostic (1.80e-1)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (1.15e-6)" "unprognostic (1.42e-2)" "unprognostic (1.38e-1)" "unprognostic (4.37e-2)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (6.78e-2)" "unprognostic (1.66e-1)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (1.89e-1)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" KRT6C KRT6E ENSG00000170465 "Keratin 6C" P48668 12 52468516-52473805 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 482.5;esophagus: 792.4;vagina: 322.2" "Group enriched" "Detected in some" 13 "Esophageal apical cells: 5611.0;Esophageal suprabasal cells: 5141.4;Suprabasal keratinocytes: 1605.7" "Group enriched" "Detected in many" 17 "Apical squamous epithelial cells: 5611.0;Suprabasal cells: 5141.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 1854.2;Skin Cutaneous Melanoma (TCGA): 583.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 33.2;head and neck cancer: 14.4" "Skin - Hair cortex cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045697, HPA061168" Supported Approved "Intermediate filaments" NA NA 1400000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 29 "Intermediate filaments" "HPA045697: , HPA061168: " "unprognostic (2.19e-1)" "unprognostic (3.79e-2)" "unprognostic (3.45e-1)" "unprognostic (1.00e-1)" "unprognostic (8.59e-2)" "unprognostic (3.34e-1)" "potential prognostic unfavorable (1.76e-7)" "unprognostic (5.41e-2)" "unprognostic (6.42e-2)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (1.88e-1)" "unprognostic (1.83e-1)" "unprognostic (4.96e-1)" KRT7 "CK-7, CK7, K2C7, K7, SCL" ENSG00000135480 "Keratin 7" P08729 12 52232520-52252186 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 341.9;salivary gland: 952.4;thyroid gland: 405.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 7673.7;Alveolar cells type 2: 1622.9;Cytotrophoblasts: 1975.3;Epididymal clear cells: 1586.1;Extravillous trophoblasts: 5987.0;Migrating cytotrophoblasts: 2713.5;Salivary acinar cells: 1611.4;Salivary duct cells: 1683.3;Salivary ionocytes: 2130.1;Submucosal glandular cells: 1541.1;Syncytiotrophoblasts: 1377.9;Transitional alveolar cells: 1574.9;Urothelial cells: 1483.0" "Cell type enhanced" "Detected in many" "Alveolar cells: 7673.7;Trophoblast cells: 5987.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 2593.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in many" "Large ducts: 4994478684.5" "Group enriched" "Detected in many" "lung: 779614250.5;salivary gland: 1059864226.8" "CAB000028, HPA007272, HPA007315, CAB079970, CAB080115" Enhanced Supported "Intermediate filaments,Cytosol" NA NA 130000000 "Cluster 82: Salivary gland - Secretion" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 9 "Intermediate filaments, Cytosol" "CAB000028: , CAB079970: , CAB080115: , HPA007272: , HPA007315: " "unprognostic (1.15e-1)" "unprognostic (3.68e-3)" "unprognostic (7.15e-2)" "unprognostic (1.47e-1)" "unprognostic (1.72e-1)" "unprognostic (9.46e-2)" "unprognostic (1.29e-1)" "unprognostic (3.39e-2)" "unprognostic (5.96e-2)" "unprognostic (4.48e-2)" "potential prognostic favorable (4.28e-7)" "unprognostic (1.52e-1)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (2.37e-6)" "unprognostic (8.79e-2)" "unprognostic (7.59e-2)" "unprognostic (4.07e-3)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (3.96e-3)" "validated prognostic unfavorable (4.87e-5)" "validated prognostic unfavorable (4.51e-4)" "unprognostic (2.70e-2)" "unprognostic (8.53e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-1)" "unprognostic (2.68e-1)" "unprognostic (3.74e-2)" "unprognostic (5.60e-2)" "unprognostic (3.53e-2)" KRT74 "K6IRS4, KRT5C, KRT6IRS4" ENSG00000170484 "Keratin 74" Q7RTS7 12 52565782-52573843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "epididymis: 5.3;skin 1: 14.6" "Group enriched" "Detected in some" 9 "Epididymal principal cells: 2.5;Late spermatids: 7.7" "Group enriched" "Detected in some" 9 "Reproductive supporting cells: 2.5;Spermatogenic cell types: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "Gallbladder cancer: 3.6" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Group enriched" "Detected in some" 18039 "Keratinocytes: 2232421.2;Large ducts: 2200897.3;Macrophages: 978427.1" "Tissue enriched" "Detected in single" 2025 "salivary gland: 202501.2" "HPA040655, HPA048596" Enhanced Approved "Nucleoli,Intermediate filaments,Cytosol" NA NA 88000000 "Cluster 9: Skin - Hair follicle development" "Cluster 32: Non-specific - Cell proliferation" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 16 "Intermediate filaments" "Nucleoli, Cytosol" "HPA040655: , HPA048596: " KRT80 KB20 ENSG00000167767 "Keratin 80" Q6KB66 12 52168996-52192014 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 211.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 101.4;Breast lactating cells: 55.3;Breast secretory cells: 46.3;Endometrial ciliated cells: 50.8;Endometrial glandular cells: 48.0;Epididymal efferent duct ciliated cells: 52.0;Esophageal apical cells: 341.8;Pancreatic duct cells: 78.4;Salivary duct cells: 86.8;Suprabasal keratinocytes: 44.7;Syncytiotrophoblasts: 69.8;Urothelial cells: 67.0" "Cell type enhanced" "Detected in many" "Alveolar cells: 101.4;Apical squamous epithelial cells: 341.8;Ductal cells: 86.8" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Liver - Cholangiocytes, Pancreas - Ductal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 48538979.8;Keratinocytes: 113527819.5;Large ducts: 57091851.6" "Tissue enhanced" "Detected in all" "intestine: 183619758.2" "HPA077836, HPA077918" Enhanced "Intermediate filaments" No No 63000000 "Cluster 58: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 4 "Intermediate filaments" "HPA077836: , HPA077918: " "unprognostic (3.45e-1)" "unprognostic (4.18e-3)" "unprognostic (9.24e-2)" "unprognostic (6.24e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (9.83e-2)" "unprognostic (2.28e-1)" "unprognostic (3.13e-3)" "unprognostic (9.77e-2)" "unprognostic (2.26e-2)" "unprognostic (5.33e-3)" "unprognostic (9.83e-2)" "potential prognostic unfavorable (1.52e-5)" "unprognostic (2.92e-2)" "unprognostic (1.46e-1)" "unprognostic (1.87e-2)" "unprognostic (1.22e-2)" "unprognostic (7.29e-2)" "unprognostic (7.52e-3)" "unprognostic (2.58e-2)" "unprognostic (9.53e-2)" "unprognostic (8.34e-2)" "unprognostic (6.19e-2)" "unprognostic (3.30e-2)" "unprognostic (1.15e-1)" "unprognostic (2.63e-1)" "unprognostic (3.53e-1)" "unprognostic (2.46e-2)" KYAT1 "CCBL1, GTK, KATI" ENSG00000171097 "Kynurenine aminotransferase 1" Q16773 9 128832942-128882494 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 37.9;Bergmann glia: 54.8;Brain excitatory neurons: 43.2;Brain inhibitory neurons: 47.6;Choroid plexus epithelial cells: 77.7;Distal convoluted tubule cells: 28.6;Ependymal cells: 25.4;Loop of henle epithelial cells: 30.7;Oligodendrocyte progenitor cells: 19.8;Oligodendrocytes: 22.4;Other brain neurons: 33.8;Papillary tip epithelial cells: 24.6;Podocytes: 79.5;Proximal tubule cells: 29.6;Renal collecting duct principal cells: 29.5;Renal connecting tubule cells: 29.8" "Group enriched" "Detected in some" 8 "Ciliated cells: 77.7;Ductal cells: 29.8;Glial cells: 54.8;Neuronal cells: 47.6;Renal nephron cells: 79.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 7824728.3" "Low tissue specificity" "Detected in many" "HPA021176, HPA021177, HPA027736" Approved Supported Cytosol NA NA 11000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" 4 Cytosol "HPA021176: , HPA021177: , HPA027736: " "unprognostic (1.24e-1)" "unprognostic (2.95e-2)" "unprognostic (1.93e-1)" "unprognostic (4.73e-3)" "unprognostic (1.96e-1)" "unprognostic (1.45e-2)" "potential prognostic favorable (9.25e-6)" "unprognostic (2.27e-1)" "unprognostic (2.56e-1)" "potential prognostic favorable (1.22e-4)" "unprognostic (1.14e-3)" "potential prognostic favorable (5.64e-5)" "unprognostic (4.80e-2)" "unprognostic (3.22e-2)" "unprognostic (5.32e-2)" "unprognostic (4.03e-2)" "unprognostic (7.57e-3)" "unprognostic (7.08e-2)" "unprognostic (4.99e-2)" "unprognostic (1.19e-1)" "unprognostic (1.25e-2)" "unprognostic (1.84e-1)" "unprognostic (2.22e-1)" "unprognostic (1.90e-1)" "unprognostic (3.34e-1)" "unprognostic (5.88e-2)" "unprognostic (6.73e-2)" "unprognostic (2.98e-2)" "unprognostic (2.64e-2)" KYAT3 "CCBL2, KAT3, KATIII, RBM1, RP11-82K18.3" ENSG00000137944 "Kynurenine aminotransferase 3" Q6YP21 1 88935773-88992953 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA026538, HPA027168" Enhanced Approved "Nucleoli,Cytokinetic bridge,Cytosol" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 2 Cytosol "Nucleoli, Cytokinetic bridge" "HPA026538: , HPA027168: " "unprognostic (1.16e-2)" "potential prognostic favorable (4.76e-5)" "unprognostic (1.24e-1)" "potential prognostic favorable (4.52e-4)" "unprognostic (1.40e-2)" "unprognostic (3.28e-2)" "unprognostic (1.42e-1)" "unprognostic (3.29e-3)" "unprognostic (6.40e-2)" "potential prognostic favorable (6.60e-8)" "unprognostic (1.72e-3)" "potential prognostic favorable (1.32e-5)" "unprognostic (9.45e-2)" "unprognostic (3.39e-2)" "unprognostic (1.75e-2)" "unprognostic (8.31e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-2)" "unprognostic (4.41e-1)" "unprognostic (1.49e-1)" "unprognostic (1.32e-1)" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (1.32e-1)" "unprognostic (2.73e-1)" "unprognostic (1.30e-1)" "unprognostic (4.35e-2)" "unprognostic (8.24e-2)" "unprognostic (5.63e-2)" KYNU ENSG00000115919 Kynureninase Q16719 2 142877657-143055833 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 82.6;urinary bladder: 48.0" "Cell type enhanced" "Detected in many" "B-cells: 234.9;cDC: 837.5;Endometrial secretory cells: 330.9;Kupffer cells: 259.3;Macrophages: 585.3;Megakaryocyte-Erythroid progenitors: 251.1;monocytes: 1977.3;Syncytiotrophoblasts: 408.3;Urothelial cells: 346.0" "Cell type enhanced" "Detected in many" "dendritic cells: 837.5;Mononuclear phagocytes: 1977.3" "Group enriched" "Detected in some" 15 "central nervous system macrophage: 180.0;endothelial cell: 66.6;leukocyte: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 17 "classical monocyte: 109.6;intermediate monocyte: 142.9;memory B-cell: 73.8;myeloid DC: 111.3;naive B-cell: 51.6;non-classical monocyte: 124.0;plasmacytoid DC: 77.8" "Group enriched" "Detected in many" 19 "B-cells: 73.8;dendritic cells: 111.3;monocytes: 142.9" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Macrophages, Stomach - Macrophages, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 21102996.3;Hepatocytes: 38333072.5;Proximal tubules: 24266539.1" "Tissue enriched" "Detected in many" "liver: 32613303.3" HPA031686 Enhanced Supported Nucleoplasm,Cytosol NA NA 550000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 2 Cytosol Nucleoplasm "HPA031686: " "unprognostic (1.59e-1)" "unprognostic (2.26e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.56e-4)" "unprognostic (3.59e-1)" "unprognostic (7.51e-2)" "unprognostic (4.08e-2)" "unprognostic (3.24e-1)" "unprognostic (7.38e-2)" "unprognostic (1.60e-2)" "unprognostic (1.82e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (2.63e-2)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (1.35e-1)" "unprognostic (8.47e-2)" "unprognostic (1.48e-1)" "unprognostic (1.91e-1)" "unprognostic (8.76e-2)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (6.85e-5)" "unprognostic (5.28e-2)" "unprognostic (8.72e-2)" "unprognostic (1.89e-2)" "unprognostic (3.05e-2)" "unprognostic (1.01e-2)" "unprognostic (5.05e-2)" "unprognostic (2.97e-2)" "unprognostic (2.97e-1)" L1CAM "CAML1, CD171, HSAS, HSAS1, MASA, MIC5, NCAM-L1, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.9;intestine: 47.5" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 85.1;Brain excitatory neurons: 32.9;Brain inhibitory neurons: 25.3;Melanocytes: 47.9;Other brain neurons: 44.3;Renal collecting duct principal cells: 41.0;Retinal ganglion cells: 34.8;Retinal horizontal cells: 20.0;Schwann cells: 186.8" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 85.1;Ductal cells: 41.0;Glial cells: 186.8;Neuronal cells: 44.3;Pigment cells: 47.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 114.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 288.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 93422377.0;Collecting ducts: 111859877.2;Microglia and Neuropil: 115114108.0;Neurons: 36918944.2" "Tissue enriched" "Detected in many" "cerebral cortex: 418505127.5" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 13000000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 8 "Nucleoplasm, Plasma membrane" "CAB010896: " "unprognostic (5.60e-2)" "unprognostic (3.02e-3)" "unprognostic (1.12e-1)" "unprognostic (2.95e-2)" "unprognostic (1.88e-1)" "unprognostic (5.01e-2)" "unprognostic (3.49e-2)" "unprognostic (3.43e-2)" "unprognostic (8.82e-3)" "unprognostic (3.16e-2)" "validated prognostic unfavorable (7.43e-6)" "validated prognostic unfavorable (1.01e-4)" "unprognostic (1.68e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (1.98e-1)" "unprognostic (1.16e-3)" "unprognostic (1.83e-1)" "unprognostic (1.87e-1)" "unprognostic (6.44e-2)" "unprognostic (2.94e-2)" "unprognostic (2.60e-3)" "unprognostic (8.42e-2)" "unprognostic (9.50e-2)" "unprognostic (7.11e-3)" "unprognostic (1.03e-1)" "unprognostic (3.05e-1)" "unprognostic (2.62e-1)" "unprognostic (3.16e-3)" L3MBTL1 "dJ138B7.3, DKFZp586P1522, KIAA0681, L3MBTL, ZC2HC3" ENSG00000185513 "L3MBTL histone methyl-lysine binding protein 1" Q9Y468 20 43489442-43550954 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 13.5" "Cell type enhanced" "Detected in some" "Astrocytes: 23.8;Bergmann glia: 24.0;Brain excitatory neurons: 30.0;Brain inhibitory neurons: 31.0;Choroid plexus epithelial cells: 22.8;Distal convoluted tubule cells: 25.2;Ependymal cells: 17.5;Loop of henle epithelial cells: 22.7;Microglia: 14.8;Oligodendrocyte progenitor cells: 31.3;Oligodendrocytes: 34.5;Other brain neurons: 30.5;Papillary tip epithelial cells: 17.5;Podocytes: 24.8;Proximal tubule cells: 22.1;Renal collecting duct intercalated cells: 23.4;Renal collecting duct principal cells: 24.0;Renal connecting tubule cells: 19.6" "Group enriched" "Detected in some" 8 "Ciliated cells: 22.8;Ductal cells: 24.0;Glial cells: 34.5;Neuronal cells: 31.0;Renal nephron cells: 25.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 4.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA059648 Supported "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 102: Non-specific - Mixed function" 40 Nucleoplasm "Nuclear bodies, Midbody ring" "HPA059648: " "unprognostic (1.38e-1)" "unprognostic (1.14e-2)" "unprognostic (8.69e-3)" "unprognostic (2.04e-1)" "unprognostic (1.82e-3)" "unprognostic (9.53e-2)" "unprognostic (8.05e-3)" "unprognostic (7.86e-2)" "unprognostic (1.25e-1)" "unprognostic (1.09e-3)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (4.30e-4)" "unprognostic (1.46e-1)" "unprognostic (3.02e-2)" "unprognostic (1.93e-1)" "unprognostic (4.75e-2)" "unprognostic (2.74e-2)" L3MBTL3 KIAA1798 ENSG00000198945 "L3MBTL histone methyl-lysine binding protein 3" Q96JM7 6 130013699-130141449 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 117.2;B-cells: 90.9;Choroid plexus epithelial cells: 101.9;Pituicytes/FSCs: 234.7" "Cell type enhanced" "Detected in many" "Glial cells: 234.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 623692.0;Neurons: 174443.8;T-cells: 159586.4" "Not detected" "Not detected" "HPA044382, HPA053035" Approved Supported "Nucleoplasm,Nucleoli,Vesicles,Cytokinetic bridge,Primary cilium" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 43 "Nucleoplasm, Nucleoli" "Vesicles, Cytokinetic bridge, Primary cilium" "HPA044382: , HPA053035: " "unprognostic (2.52e-1)" "unprognostic (4.08e-1)" "unprognostic (3.59e-1)" "unprognostic (4.31e-2)" "unprognostic (1.16e-1)" "unprognostic (7.70e-3)" "unprognostic (1.79e-2)" "unprognostic (1.10e-1)" "unprognostic (3.76e-2)" "unprognostic (1.45e-2)" "potential prognostic favorable (4.65e-4)" "unprognostic (3.22e-2)" "unprognostic (1.22e-1)" "unprognostic (5.61e-3)" "unprognostic (8.99e-2)" "unprognostic (7.72e-3)" "unprognostic (1.64e-2)" "unprognostic (6.78e-2)" "unprognostic (1.38e-1)" "unprognostic (2.78e-2)" "unprognostic (7.27e-2)" "unprognostic (1.92e-2)" "unprognostic (3.79e-3)" "unprognostic (1.72e-1)" "unprognostic (1.99e-1)" "unprognostic (8.45e-2)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (1.79e-2)" "unprognostic (2.20e-1)" "unprognostic (2.93e-2)" "unprognostic (6.47e-2)" LACTBL1 ENSG00000215906 "Lactamase beta like 1" 1 22953043-22972866 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 18 "retina: 3.6" "Cell type enriched" "Detected in some" 8 "Retinal bipolar cells: 33.9" "Cell type enriched" "Detected in some" 8 "Neuronal cells: 33.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA066810 Approved "Nuclear bodies" NA NA "Cluster 42: Retina - Visual perception" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nuclear bodies" "HPA066810: " LAMC2 "BM600-100kDa, EBR2, EBR2A, kalinin-105kDa, LAMB2T, LAMNB2, nicein-100kDa" ENSG00000058085 "Laminin subunit gamma 2" Q13753 1 183186238-183245127 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 36.5" "Cell type enriched" "Detected in many" 6 "Epididymal basal cells: 5218.8" "Cell type enriched" "Detected in many" 6 "Basal cells: 5218.8" "Cell type enhanced" "Detected in many" "upper rhombic lip: 8.5" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 403.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 511.2" "Breast - Breast myoepithelial cells, Liver - Cholangiocytes, Pancreas - Ductal cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" "Alveolar cell types: 88691573.6" "Tissue enriched" "Detected in many" "lung: 60706913.7" "CAB004257, HPA024638, HPA046539, HPA046540, CAB078165" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus" "Secreted to extracellular matrix" "Cell adhesion" No No 27000 "Cluster 13: Lung - Secretion" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 4 "Endoplasmic reticulum, Golgi apparatus" "CAB004257: , CAB078165: , HPA024638: , HPA046539: , HPA046540: " "unprognostic (1.17e-1)" "unprognostic (1.07e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (9.80e-2)" "unprognostic (3.57e-1)" "unprognostic (4.63e-2)" "unprognostic (4.25e-3)" "unprognostic (2.72e-2)" "unprognostic (1.74e-1)" "unprognostic (7.78e-2)" "unprognostic (3.83e-2)" "unprognostic (4.42e-2)" "unprognostic (1.36e-1)" "potential prognostic unfavorable (5.82e-6)" "unprognostic (1.02e-2)" "unprognostic (4.56e-3)" "potential prognostic unfavorable (4.73e-6)" "unprognostic (2.32e-1)" "unprognostic (9.19e-2)" "potential prognostic unfavorable (7.41e-5)" "unprognostic (4.32e-2)" "unprognostic (3.33e-1)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" "unprognostic (1.70e-1)" "unprognostic (2.22e-1)" "unprognostic (2.90e-1)" "unprognostic (1.09e-1)" "unprognostic (6.00e-2)" LAMP5 "BAD-LAMP, C20orf103, dJ1119D9.3, UNC-46" ENSG00000125869 "Lysosomal associated membrane protein family member 5" Q9UJQ1 20 9514358-9530524 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 297.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 92.0;Brain inhibitory neurons: 72.8;Granulosa cells: 142.7;Megakaryocytes: 30.9;Ovarian stromal cells: 65.0;pDCs: 215.6;Plasma cells: 31.2;Retinal horizontal cells: 36.1" "Cell type enhanced" "Detected in many" "dendritic cells: 215.6;Glial cells: 92.0;Neuronal cells: 72.8;Reproductive supporting cells: 142.7;Stromal cells: 65.0" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 305.4;medium spiny neuron: 143.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "plasmacytoid DC: 141.6" "Lineage enriched" "Detected in many" 31 "dendritic cells: 141.6" "Group enriched" "Detected in some" 8 "Leukemia: 56.6;Myeloma: 90.7;Neuroblastoma: 37.5" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Pituitary gland - Thyrotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 953600.1;Microglia and Neuropil: 1094599.2;Neurons: 468607.1;Oocytes: 941572.2" "Tissue enriched" "Detected in single" 57341 "cerebral cortex: 5734134.4" "HPA004802, HPA070765" Enhanced Uncertain "Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 Cytosol "Mitotic spindle, Centriolar satellite" "HPA004802: , HPA070765: " "unprognostic (4.54e-2)" "unprognostic (5.59e-2)" "unprognostic (6.16e-3)" "potential prognostic unfavorable (8.57e-4)" "unprognostic (7.09e-2)" "unprognostic (9.29e-3)" "unprognostic (2.84e-1)" "unprognostic (2.53e-1)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (2.65e-1)" "unprognostic (2.24e-3)" "unprognostic (2.62e-3)" "unprognostic (1.87e-1)" "unprognostic (8.52e-2)" "unprognostic (6.68e-2)" "unprognostic (1.04e-2)" "unprognostic (1.56e-1)" "unprognostic (1.35e-1)" "unprognostic (8.36e-2)" "unprognostic (2.76e-2)" "unprognostic (1.00e-1)" "unprognostic (4.47e-1)" "unprognostic (3.78e-2)" "unprognostic (5.40e-2)" "unprognostic (3.14e-3)" "unprognostic (1.29e-2)" "unprognostic (1.68e-2)" "unprognostic (7.85e-2)" LAMTOR2 "ENDAP, MAPBPIP, MAPKSP1AP, p14, Ragulator2, ROBLD3" ENSG00000116586 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 2" Q9Y2Q5 1 156054782-156058506 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 401.6;Esophageal suprabasal cells: 364.9;Hepatocytes: 361.0;Hofbauer cells: 576.6" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 576.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 1651876.2" "Low tissue specificity" "Detected in all" HPA004126 Approved Approved Nucleoplasm,Vesicles No No 8000 "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 49 "Nucleoplasm, Vesicles" "HPA004126: " "unprognostic (3.46e-3)" "unprognostic (2.85e-1)" "unprognostic (3.28e-2)" "unprognostic (9.06e-2)" "unprognostic (4.43e-2)" "unprognostic (3.96e-2)" "unprognostic (2.92e-1)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "potential prognostic unfavorable (1.78e-7)" "unprognostic (8.96e-3)" "unprognostic (2.53e-2)" "unprognostic (1.79e-2)" "unprognostic (6.71e-2)" "unprognostic (1.74e-1)" "unprognostic (2.07e-1)" "unprognostic (2.08e-1)" "unprognostic (1.25e-1)" "unprognostic (5.18e-2)" "unprognostic (6.51e-2)" "unprognostic (1.24e-1)" "unprognostic (5.58e-2)" "unprognostic (1.21e-2)" "unprognostic (2.26e-2)" "unprognostic (7.63e-2)" "unprognostic (2.94e-1)" "unprognostic (3.33e-2)" "unprognostic (4.43e-1)" "unprognostic (2.10e-1)" "unprognostic (9.91e-2)" LANCL1 "GPR69A, p40" ENSG00000115365 "LanC like glutathione S-transferase 1" O43813 2 210427131-210477652 "Enzymes, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 161.6" "Cell type enhanced" "Detected in many" "Lactotrophs: 221.7;Oligodendrocytes: 662.4;Pituicytes/FSCs: 200.6" "Cell type enhanced" "Detected in all" "Glial cells: 662.4;Pituitary endocrine cells: 221.7" "Cell type enhanced" "Detected in all" "oligodendrocyte: 992.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 62130637.2" HPA034994 Enhanced Approved "Microtubules,Primary cilium,Basal body,Flagellar centriole,End piece" NA NA 22000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 80: Oligodendrocytes - Myelination" 23 "Microtubules, Primary cilium, Basal body, End piece" "Flagellar centriole" "HPA034994: " "unprognostic (6.61e-3)" "unprognostic (5.92e-2)" "unprognostic (2.68e-1)" "unprognostic (2.71e-1)" "unprognostic (2.10e-1)" "unprognostic (2.54e-1)" "unprognostic (1.84e-1)" "unprognostic (1.70e-2)" "unprognostic (9.42e-2)" "unprognostic (1.71e-3)" "potential prognostic favorable (1.22e-7)" "unprognostic (6.65e-3)" "unprognostic (1.43e-1)" "unprognostic (2.00e-2)" "unprognostic (2.85e-2)" "unprognostic (2.97e-2)" "unprognostic (2.81e-2)" "unprognostic (2.14e-1)" "unprognostic (3.03e-1)" "unprognostic (3.04e-2)" "unprognostic (5.30e-2)" "unprognostic (1.47e-2)" "unprognostic (3.04e-1)" "unprognostic (1.05e-1)" "unprognostic (9.06e-2)" "unprognostic (7.68e-3)" "unprognostic (8.55e-2)" "unprognostic (3.43e-1)" "unprognostic (1.29e-2)" "unprognostic (7.42e-2)" "unprognostic (1.40e-1)" LAP3 "LAP, LAPEP, PEPS" ENSG00000002549 "Leucine aminopeptidase 3" P28838 4 17577198-17607972 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 219.4;Hofbauer cells: 374.7;Late primary spermatocytes: 202.0" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 374.7" "Cell type enhanced" "Detected in all" "endothelial cell: 82.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "liver: 480241322.6" "HPA029606, HPA029607" Enhanced Approved "Cytosol,Calyx,Mid piece,Principal piece" NA No 8000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 15 Cytosol "Calyx, Mid piece, Principal piece" "HPA029606: , HPA029607: " "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "unprognostic (8.74e-3)" "unprognostic (1.30e-1)" "unprognostic (7.42e-2)" "unprognostic (1.10e-1)" "unprognostic (8.95e-2)" "unprognostic (2.01e-1)" "unprognostic (4.51e-1)" "unprognostic (6.17e-2)" "potential prognostic favorable (9.89e-5)" "unprognostic (2.87e-2)" "unprognostic (1.02e-2)" "unprognostic (4.15e-2)" "unprognostic (5.62e-2)" "unprognostic (1.06e-1)" "unprognostic (3.18e-2)" "unprognostic (2.82e-3)" "unprognostic (3.46e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-1)" "unprognostic (1.68e-2)" "unprognostic (2.47e-1)" "unprognostic (2.58e-1)" "unprognostic (7.32e-2)" "unprognostic (4.02e-2)" "unprognostic (4.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.44e-2)" "unprognostic (4.42e-1)" "unprognostic (2.31e-1)" LARP6 "acheron, FLJ11196" ENSG00000166173 "La ribonucleoprotein 6, translational regulator" Q9BRS8 15 70829130-70854157 "Predicted intracellular proteins" "Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 123.6" "Cell type enhanced" "Detected in many" "Early spermatids: 365.0;Epididymal efferent duct absorptive cells: 98.2;Epididymal efferent duct ciliated cells: 141.4;Epididymal principal cells: 231.1;Late primary spermatocytes: 481.3;Late spermatids: 328.2;Oligodendrocytes: 141.9" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 231.1;Spermatogenic cell types: 481.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 166.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 6678124.3;Neurons: 7690665.9" "Group enriched" "Detected in many" "cerebral cortex: 6403518.5;kidney: 3914497.1" "HPA020338, HPA049029" Approved Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 4 Microtubules "Cytokinetic bridge" "HPA020338: , HPA049029: " "unprognostic (8.72e-2)" "potential prognostic favorable (7.89e-4)" "unprognostic (1.77e-1)" "unprognostic (3.82e-1)" "unprognostic (1.04e-1)" "unprognostic (4.13e-2)" "unprognostic (2.31e-2)" "unprognostic (1.51e-1)" "unprognostic (1.58e-2)" "unprognostic (9.94e-2)" "unprognostic (2.15e-2)" "unprognostic (4.95e-3)" "unprognostic (2.72e-1)" "unprognostic (9.88e-3)" "unprognostic (1.57e-2)" "unprognostic (5.21e-3)" "unprognostic (2.78e-1)" "unprognostic (2.56e-2)" "unprognostic (1.77e-2)" "unprognostic (2.75e-2)" "unprognostic (4.04e-1)" "unprognostic (3.89e-2)" "unprognostic (2.44e-3)" "unprognostic (3.57e-2)" "unprognostic (1.81e-1)" "unprognostic (6.47e-2)" "unprognostic (1.41e-1)" "unprognostic (3.51e-3)" "unprognostic (3.62e-2)" "unprognostic (2.44e-1)" "unprognostic (3.49e-2)" LARS1 "FLJ10595, FLJ21788, HSPC192, LARS, LEUS, RNTLS" ENSG00000133706 "Leucyl-tRNA synthetase 1" Q9P2J5 5 146110566-146182696 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA036424, HPA040881" Supported Approved "Nuclear bodies,Cytosol" NA NA 78000 "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 49 "Nuclear bodies, Cytosol" "HPA036424: , HPA040881: " "unprognostic (6.61e-2)" "unprognostic (4.30e-3)" "unprognostic (2.28e-1)" "unprognostic (2.75e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "unprognostic (1.37e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.75e-5)" "potential prognostic favorable (1.88e-4)" "unprognostic (9.53e-2)" "unprognostic (4.83e-1)" "potential prognostic unfavorable (3.06e-5)" "unprognostic (1.29e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (8.93e-4)" "unprognostic (1.38e-1)" "unprognostic (2.96e-2)" "unprognostic (2.75e-2)" "unprognostic (1.36e-1)" "unprognostic (1.75e-1)" "unprognostic (6.21e-2)" "unprognostic (1.30e-3)" "unprognostic (1.67e-1)" "unprognostic (4.44e-2)" "unprognostic (5.78e-2)" "unprognostic (7.80e-2)" "unprognostic (1.19e-2)" "unprognostic (1.59e-1)" LAS1L "FLJ12525, Las1" ENSG00000001497 "LAS1 like ribosome biogenesis factor" Q9Y4W2 X 65438549-65534810 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "rRNA processing" Hydrolase "Disease variant, Intellectual disability, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 235.2;Sertoli cells: 111.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 235.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 40912327.7" "Tissue enhanced" "Detected in many" "bone marrow: 3337068.2" "HPA044431, HPA061463" Supported Approved "Nucleoplasm,Primary cilium transition zone,Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 51 Nucleoplasm "Primary cilium transition zone, Centriolar satellite, Centrosome, Basal body, Cytosol" "HPA044431: , HPA061463: " "unprognostic (1.04e-1)" "unprognostic (8.13e-3)" "unprognostic (2.47e-1)" "unprognostic (2.64e-3)" "unprognostic (9.13e-2)" "unprognostic (6.41e-2)" "unprognostic (2.95e-1)" "potential prognostic favorable (9.08e-4)" "unprognostic (9.47e-3)" "unprognostic (2.12e-2)" "unprognostic (2.27e-3)" "unprognostic (8.36e-2)" "unprognostic (6.82e-2)" "unprognostic (2.64e-2)" "unprognostic (1.11e-3)" "unprognostic (6.10e-2)" "unprognostic (4.06e-3)" "unprognostic (3.29e-2)" "unprognostic (1.15e-1)" "unprognostic (8.57e-2)" "unprognostic (9.90e-2)" "unprognostic (3.53e-2)" "unprognostic (2.48e-1)" "unprognostic (4.37e-2)" "unprognostic (4.46e-1)" "unprognostic (5.31e-2)" "unprognostic (1.71e-1)" "unprognostic (7.63e-2)" "potential prognostic favorable (7.60e-4)" "unprognostic (3.72e-2)" "unprognostic (2.69e-2)" LATS2 ENSG00000150457 "Large tumor suppressor kinase 2" Q9NRM7 13 20973036-21061586 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 250.1;Neutrophils: 446.0" "Cell type enhanced" "Detected in many" "Neutrophils: 446.0" "Cell type enhanced" "Detected in many" "endothelial cell: 124.1;fibroblast: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039191, HPA049037" Approved Approved "Centriolar satellite,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 72 "Centriolar satellite, Cytosol" "HPA039191: , HPA049037: " "potential prognostic favorable (9.37e-4)" "unprognostic (2.59e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (3.08e-2)" "unprognostic (2.99e-2)" "unprognostic (9.01e-2)" "potential prognostic unfavorable (2.24e-6)" "unprognostic (3.24e-2)" "potential prognostic favorable (8.96e-4)" "potential prognostic favorable (4.53e-6)" "unprognostic (2.42e-3)" "unprognostic (7.98e-2)" "unprognostic (1.76e-1)" "unprognostic (7.41e-2)" "unprognostic (5.21e-3)" "unprognostic (2.93e-2)" "unprognostic (1.40e-2)" "unprognostic (2.99e-1)" "unprognostic (2.02e-3)" "unprognostic (2.81e-3)" "unprognostic (4.23e-2)" "unprognostic (9.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.30e-2)" "unprognostic (5.01e-2)" "unprognostic (2.50e-1)" "unprognostic (2.10e-2)" "unprognostic (2.68e-1)" "unprognostic (9.29e-2)" "unprognostic (9.29e-2)" LBX1 "HPX6, LBX1H" ENSG00000138136 "Ladybird homeobox 1" P52954 10 101226994-101229463 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "skeletal muscle: 23.7" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 10 "cerebellar inhibitory: 13.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebellum: 4.4;medulla oblongata: 8.1;pons: 6.0;spinal cord: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 5.0" "Group enriched" "Detected in some" 24 "cerebellum: 1.6;pons and medulla: 3.0" "Group enriched" "Detected in some" 23 "cerebellum: 1.6;medulla oblongata: 2.6;spinal cord: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002016, HPA002086, CAB079927" Uncertain Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 43: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 20 Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB079927: , HPA002016: , HPA002086: " LBX2 ENSG00000179528 "Ladybird homeobox 2" Q6XYB7 2 74497517-74503316 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 5.0;liver: 9.1;stomach 1: 3.0" "Cell type enhanced" "Detected in many" "Enterocytes: 5.6;Epididymal efferent duct absorptive cells: 5.4;Gastric chief cells: 6.6;Gastric progenitor cells: 7.7;Hepatocytes: 5.8;Hofbauer cells: 6.9;Megakaryocytes: 12.4" "Cell type enhanced" "Detected in many" "Megakaryocytes: 12.4" "Cell type enhanced" "Detected in some" "endothelial cell: 1.3;fibroblast: 1.7;pericyte: 2.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA044257 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Nucleoplasm Midbody "HPA044257: " "unprognostic (2.66e-2)" "unprognostic (1.21e-1)" "unprognostic (2.10e-1)" "unprognostic (1.38e-1)" "unprognostic (1.90e-3)" "unprognostic (4.69e-2)" "unprognostic (9.14e-2)" "unprognostic (2.89e-1)" "unprognostic (3.42e-1)" "unprognostic (3.20e-2)" "unprognostic (2.01e-1)" "unprognostic (3.47e-2)" "unprognostic (5.73e-2)" "unprognostic (3.56e-1)" "unprognostic (1.46e-1)" "unprognostic (8.19e-2)" "unprognostic (2.35e-2)" "unprognostic (3.09e-1)" "unprognostic (1.19e-2)" "unprognostic (4.47e-1)" "unprognostic (1.30e-1)" "unprognostic (5.68e-1)" "unprognostic (5.03e-2)" "unprognostic (7.85e-2)" "unprognostic (8.74e-2)" "unprognostic (1.71e-2)" LCA5L "C21orf13, MGC33295" ENSG00000157578 "Lebercilin LCA5 like" O95447 21 39405728-39445805 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "testis: 103.2" "Group enriched" "Detected in many" 8 "Early spermatids: 1231.7;Late primary spermatocytes: 1581.2;Late spermatids: 684.6" "Cell type enriched" "Detected in many" 11 "Spermatogenic cell types: 1581.2" "Cell type enriched" "Detected in all" 4 "ependymal cell: 145.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 445 "Fallopian tube cells: 44480.8" "Tissue enriched" "Detected in single" 14895 "Stomach: 1489516.4" HPA032010 Enhanced Approved "Nucleoplasm,Nuclear speckles,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 "Nucleoplasm, Nuclear speckles, Flagellar centriole, Mid piece" "Cytosol, Principal piece, End piece" "HPA032010: " "unprognostic (3.76e-1)" "unprognostic (8.58e-2)" "unprognostic (3.32e-1)" "unprognostic (1.05e-2)" "unprognostic (7.79e-3)" "unprognostic (1.99e-1)" "unprognostic (1.07e-1)" "unprognostic (9.41e-2)" "unprognostic (4.26e-3)" "unprognostic (8.33e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-2)" "unprognostic (1.37e-1)" "unprognostic (5.44e-3)" "unprognostic (1.88e-1)" "unprognostic (2.38e-1)" "unprognostic (1.47e-1)" "unprognostic (1.26e-1)" "unprognostic (9.58e-2)" LCLAT1 "AGPAT8, ALCAT1, FLJ37965, LPLAT6, LYCAT" ENSG00000172954 "Lysocardiolipin acyltransferase 1" Q6UWP7 2 30447226-30644225 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 322.1" "Cell type enhanced" "Detected in all" "Myocytes: 322.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA031880, HPA049217" Uncertain Supported "Endoplasmic reticulum,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 32: Non-specific - Cell proliferation" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 10 "Endoplasmic reticulum" Cytosol "HPA031880: , HPA049217: " "unprognostic (3.41e-1)" "unprognostic (1.05e-2)" "unprognostic (2.23e-2)" "unprognostic (1.61e-2)" "unprognostic (8.86e-2)" "unprognostic (1.65e-1)" "unprognostic (2.06e-1)" "unprognostic (7.19e-3)" "unprognostic (3.07e-3)" "unprognostic (5.04e-3)" "potential prognostic favorable (3.22e-5)" "unprognostic (1.00e-1)" "unprognostic (2.97e-1)" "validated prognostic unfavorable (2.12e-4)" "validated prognostic unfavorable (7.48e-5)" "unprognostic (1.49e-2)" "unprognostic (1.91e-2)" "unprognostic (5.52e-3)" "unprognostic (1.20e-2)" "unprognostic (2.08e-1)" "unprognostic (3.31e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" "unprognostic (3.07e-2)" "unprognostic (6.88e-2)" "unprognostic (5.54e-2)" "unprognostic (2.55e-1)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (6.46e-3)" "unprognostic (1.93e-1)" LCMT1 "CGI-68, PPMT1" ENSG00000205629 "Leucine carboxyl methyltransferase 1" Q9UIC8 16 25111731-25178231 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 247.6;Oocytes: 460.5;Syncytiotrophoblasts: 205.7" "Cell type enhanced" "Detected in all" "Oocytes: 460.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 21780551.5" "Low tissue specificity" "Detected in all" "HPA041559, HPA043530" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 3 "Nucleoplasm, Cytosol" "HPA041559: , HPA043530: " "unprognostic (2.54e-1)" "unprognostic (3.77e-3)" "unprognostic (1.76e-1)" "unprognostic (8.34e-3)" "unprognostic (1.88e-1)" "unprognostic (2.92e-1)" "unprognostic (1.16e-1)" "unprognostic (1.61e-1)" "unprognostic (1.64e-1)" "unprognostic (7.35e-2)" "potential prognostic favorable (3.60e-4)" "unprognostic (2.12e-1)" "unprognostic (2.96e-2)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (1.26e-1)" "unprognostic (2.98e-2)" "unprognostic (9.85e-2)" "unprognostic (2.16e-1)" "unprognostic (3.76e-2)" "unprognostic (2.85e-1)" "unprognostic (1.64e-2)" "unprognostic (7.30e-3)" "unprognostic (1.82e-1)" "unprognostic (7.24e-3)" "unprognostic (1.45e-1)" "unprognostic (1.24e-2)" "unprognostic (2.72e-2)" "unprognostic (8.72e-2)" "unprognostic (9.63e-3)" "unprognostic (1.36e-2)" LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 669.6;epididymis: 380.4;lymphoid tissue: 566.7" "Cell type enhanced" "Detected in many" "cDC: 637.7;Epididymal principal cells: 754.0;Kupffer cells: 562.7;Late spermatids: 534.6;Monocyte progenitors: 1308.9;monocytes: 1174.8;Neutrophil progenitors: 1996.1;Neutrophils: 6753.3;NK-cells: 569.2" "Cell type enriched" "Detected in many" 5 "Neutrophils: 6753.3" "Cell type enriched" "Detected in many" 4 "leukocyte: 549.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 582.6;lymphoma: 986.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Prostate glandular cells, Skeletal muscle - Macrophages, Skin - Langerhans cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "B-cells: 492175257.4;Macrophages: 480632473.2;Neutrophils: 318979382.4;T-cells: 626222655.5" "Group enriched" "Detected in all" "bone marrow: 609553260.8;lymphoid tissue: 1542150648.0" "HPA000895, HPA019493, CAB020673" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 770000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 20 "Plasma membrane" "Actin filaments, Cytosol" "CAB020673: , HPA000895: , HPA019493: " "unprognostic (6.48e-2)" "unprognostic (1.11e-2)" "unprognostic (5.99e-3)" "unprognostic (6.13e-2)" "unprognostic (1.71e-2)" "unprognostic (1.20e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (5.92e-2)" "unprognostic (5.42e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-1)" "unprognostic (5.43e-2)" "unprognostic (1.82e-1)" "unprognostic (2.44e-1)" "unprognostic (3.43e-3)" "unprognostic (3.44e-2)" "unprognostic (7.19e-2)" "unprognostic (2.97e-1)" "unprognostic (3.18e-1)" "unprognostic (1.71e-1)" "unprognostic (2.74e-2)" "potential prognostic unfavorable (7.47e-4)" "unprognostic (1.24e-1)" "unprognostic (5.28e-2)" "unprognostic (3.77e-2)" "unprognostic (4.14e-3)" "unprognostic (1.74e-1)" "unprognostic (9.42e-2)" "unprognostic (7.22e-2)" "unprognostic (2.50e-1)" LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 583.0;Brain inhibitory neurons: 408.7;Endometrial stromal cells: 319.6;Fibro-adipogenic progenitors: 598.9;Leydig cells: 325.3;Lymphatic endothelial cells: 1916.8;Peritubular myoid cells: 326.1;Pituicytes/FSCs: 406.0;Vascular endothelial cells: 2327.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 2327.2;Fibro-adipogenic progenitors: 598.9;Neuronal cells: 583.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 51.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cancer enriched" "Detected in many" 6 "Bone cancer: 28.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Neurons: 782874.4;T-cells: 210262.9" "Group enriched" "Detected in some" 15665 "cerebral cortex: 1675540.9;ovary: 1457451.0" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 14: Non-specific - Unknown function" "Cluster 13: Lung - Secretion" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 30 "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: , HPA068634: " "unprognostic (8.44e-2)" "unprognostic (2.80e-1)" "unprognostic (4.11e-2)" "unprognostic (1.07e-1)" "unprognostic (4.28e-2)" "unprognostic (9.27e-2)" "unprognostic (8.08e-2)" "unprognostic (8.19e-2)" "unprognostic (2.17e-2)" "unprognostic (3.73e-1)" "validated prognostic favorable (4.47e-9)" "validated prognostic favorable (4.48e-4)" "unprognostic (4.27e-3)" "unprognostic (4.21e-3)" "potential prognostic favorable (4.34e-4)" "unprognostic (2.65e-2)" "unprognostic (3.10e-1)" "unprognostic (2.23e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-2)" "unprognostic (3.36e-3)" "unprognostic (2.37e-2)" "unprognostic (2.09e-2)" "unprognostic (7.96e-2)" "unprognostic (7.41e-2)" "unprognostic (2.34e-1)" "potential prognostic unfavorable (3.56e-6)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (2.75e-1)" "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" LDHA ENSG00000134333 "Lactate dehydrogenase A" P00338 11 18394560-18408425 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes, Disease variant, FDA approved drug targets, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 68.0;Ocular epithelial cells: 128.9;Other brain neurons: 90.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 128.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 1631087936.7" "Low tissue specificity" "Detected in all" "CAB015336, CAB069404, HPA075026" Uncertain Enhanced Cytosol NA NA 160000000 "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 98: Neurons - Neurotransmission & signaling" 38 Cytosol "CAB015336: , CAB069404: , HPA075026: " "unprognostic (2.96e-3)" "unprognostic (2.59e-1)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (2.29e-1)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (8.71e-7)" "potential prognostic favorable (1.22e-6)" "unprognostic (2.02e-1)" "unprognostic (1.26e-3)" "validated prognostic unfavorable (6.75e-9)" "validated prognostic unfavorable (4.81e-6)" "validated prognostic unfavorable (2.07e-7)" "validated prognostic unfavorable (7.09e-5)" "unprognostic (6.23e-2)" "unprognostic (2.83e-1)" "unprognostic (7.11e-2)" "unprognostic (4.23e-2)" "validated prognostic unfavorable (4.52e-6)" "validated prognostic unfavorable (7.22e-4)" "unprognostic (1.90e-3)" "unprognostic (4.76e-3)" "unprognostic (1.14e-1)" "unprognostic (2.63e-2)" "unprognostic (1.20e-2)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" "unprognostic (2.23e-1)" LDHB ENSG00000111716 "Lactate dehydrogenase B" P07195 12 21635342-21757857 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1824.5;kidney: 1610.4" "Cell type enriched" "Detected in many" 5 "Parietal cells: 1143.8" "Cell type enriched" "Detected in many" 5 "Gastric glandular cells: 1143.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004641, HPA019007" Enhanced Supported "Primary cilium,Cytosol" No No 390000000 "Cluster 39: T-cells - T-cell receptor" "Cluster 52: Non-specific - Cellular respiration" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 39 Cytosol "Primary cilium" "CAB004641: , HPA019007: " "unprognostic (7.47e-2)" "unprognostic (3.29e-1)" "unprognostic (1.12e-1)" "unprognostic (1.95e-1)" "unprognostic (5.43e-2)" "unprognostic (4.39e-2)" "unprognostic (2.46e-3)" "unprognostic (1.52e-3)" "unprognostic (3.39e-3)" "unprognostic (4.03e-2)" "potential prognostic favorable (7.02e-5)" "unprognostic (1.27e-2)" "unprognostic (3.69e-1)" "unprognostic (3.71e-2)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (8.99e-5)" "unprognostic (9.36e-2)" "unprognostic (2.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.86e-1)" "unprognostic (1.12e-2)" "unprognostic (1.67e-1)" "unprognostic (3.55e-3)" "unprognostic (2.22e-1)" "unprognostic (7.04e-3)" "unprognostic (3.09e-2)" "unprognostic (1.57e-1)" "unprognostic (2.13e-1)" "unprognostic (1.89e-1)" "unprognostic (2.89e-1)" "unprognostic (9.25e-2)" LDHC CT32 ENSG00000166796 "Lactate dehydrogenase C" P07864 11 18412318-18452063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 179 "testis: 247.8" "Group enriched" "Detected in many" 6 "Early spermatids: 1059.7;Late primary spermatocytes: 4060.8" "Cell type enriched" "Detected in many" 85 "Spermatogenic cell types: 4060.8" "Low cell type specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA045442 Enhanced Supported "Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 15 Cytosol "Mid piece, Principal piece, End piece" "HPA045442: " "unprognostic (1.83e-1)" "unprognostic (1.96e-3)" "unprognostic (1.53e-1)" "unprognostic (1.46e-1)" "unprognostic (2.63e-1)" "unprognostic (2.27e-1)" "unprognostic (4.16e-1)" LDHD ENSG00000166816 "Lactate dehydrogenase D" Q86WU2 16 75111860-75116780 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 78.8;liver: 126.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 50.6;Colonocytes: 73.2;Esophageal apical cells: 40.8;Foveolar cells: 24.4;Hepatocytes: 94.7;Parietal cells: 58.3" "Cell type enhanced" "Detected in many" "Enterocytes: 73.2;Gastric glandular cells: 58.3;Hepatocytes: 94.7;Secretory cells: 50.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 19.3" "Group enriched" "Detected in all" 4 "Kidney Chromophobe (TCGA): 85.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 54.3;Liver Hepatocellular Carcinoma (TCGA): 46.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 11.0" "Group enriched" "Detected in many" 45 "granulocytes: 11.0;monocytes: 4.8" "Cancer enhanced" "Detected in many" "prostate cancer: 10.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 61967815.8;Proximal tubules: 102456121.8" "Tissue enhanced" "Detected in many" "kidney: 56118492.7;liver: 82433459.6" "HPA041766, HPA048639, HPA066148" Enhanced Approved Mitochondria,Cytosol No NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Cytosol Mitochondria "HPA041766: , HPA048639: , HPA066148: " "unprognostic (1.30e-1)" "unprognostic (4.84e-2)" "unprognostic (2.42e-2)" "unprognostic (3.60e-2)" "unprognostic (9.27e-2)" "unprognostic (1.97e-1)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (5.64e-2)" "unprognostic (3.40e-2)" "potential prognostic favorable (3.43e-9)" "unprognostic (2.45e-2)" "potential prognostic favorable (3.97e-5)" "potential prognostic favorable (5.89e-4)" "unprognostic (3.75e-3)" "unprognostic (7.01e-3)" "unprognostic (1.73e-3)" "unprognostic (3.65e-1)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.51e-1)" "unprognostic (1.90e-1)" "unprognostic (5.54e-2)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (8.88e-3)" "unprognostic (4.14e-2)" "unprognostic (1.84e-2)" "unprognostic (4.22e-2)" "unprognostic (6.23e-2)" "unprognostic (1.54e-1)" LDLRAD1 ENSG00000203985 "Low density lipoprotein receptor class A domain containing 1" Q5T700 1 54007298-54018186 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "fallopian tube: 109.3" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 129.4;Epididymal efferent duct ciliated cells: 93.2;Fallopian tube ciliated cells: 428.3;Respiratory ciliated cells: 370.7" "Cell type enriched" "Detected in some" 33 "Ciliated cells: 428.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA052489 Enhanced Approved "Nucleoplasm,Golgi apparatus,Primary cilium" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 48: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 85 Nucleoplasm "Golgi apparatus, Primary cilium" "HPA052489: " "potential prognostic favorable (8.07e-4)" "unprognostic (1.78e-2)" "unprognostic (2.43e-1)" "unprognostic (1.74e-1)" "unprognostic (2.16e-1)" "unprognostic (2.98e-1)" "unprognostic (2.20e-1)" "unprognostic (2.60e-1)" "unprognostic (1.77e-1)" "unprognostic (1.12e-1)" "unprognostic (2.49e-1)" "unprognostic (9.97e-3)" "unprognostic (7.77e-2)" "unprognostic (8.11e-2)" "unprognostic (3.76e-2)" LEF1 "TCF10, TCF1ALPHA, TCF7L3" ENSG00000138795 "Lymphoid enhancer binding factor 1" Q9UJU2 4 108047545-108168956 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 27 "lymphoid tissue: 325.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 94.1;Choroid plexus epithelial cells: 264.9;Endometrial stromal cells: 73.6;Ependymal cells: 107.5;Melanocytes: 213.5;Pituicytes/FSCs: 72.1;Renal collecting duct intercalated cells: 255.8;T-cells: 142.3;Thymocytes: 347.2;Vascular endothelial cells: 82.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 264.9;Ductal cells: 255.8;Pigment cells: 213.5;T-cells: 347.2" "Cell type enhanced" "Detected in many" "endothelial cell: 1148.3;pericyte: 340.2" "Cancer enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 54.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 143.0" "Lineage enriched" "Detected in many" 4 "T-cells: 143.0" "Cancer enhanced" "Detected in many" "Leukemia: 151.1" "Adrenal gland - Adrenal cortex cells, Skin - Inner root sheath cells, Spleen - T-cells, Testis - Early spermatids" "Region enhanced" "Detected in all" "thalamus: 22.6" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4326 "T-cells: 432598.9" "Not detected" "Not detected" "HPA002087, CAB019405" Enhanced Approved Nucleoplasm NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 80: Thymus - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 9: T-cells - Adaptive immunity: Regulation" 23 Nucleoplasm "CAB019405: , HPA002087: " "unprognostic (2.39e-1)" "unprognostic (1.94e-3)" "unprognostic (3.46e-2)" "unprognostic (3.60e-2)" "unprognostic (1.10e-1)" "unprognostic (1.42e-1)" "unprognostic (3.42e-1)" "unprognostic (3.80e-3)" "unprognostic (4.92e-2)" "unprognostic (3.11e-1)" "unprognostic (2.66e-2)" "unprognostic (5.73e-2)" "unprognostic (1.14e-2)" "unprognostic (3.88e-1)" "unprognostic (3.73e-2)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (5.24e-2)" "unprognostic (7.55e-2)" "unprognostic (3.84e-1)" "unprognostic (2.73e-1)" "unprognostic (1.89e-1)" "unprognostic (3.82e-1)" "unprognostic (5.56e-2)" "unprognostic (1.76e-1)" "unprognostic (6.82e-2)" "unprognostic (2.98e-1)" "unprognostic (6.62e-2)" "unprognostic (4.58e-2)" "unprognostic (2.09e-2)" "unprognostic (2.84e-2)" LEKR1 FLJ16641 ENSG00000197980 "Leucine, glutamate and lysine rich 1" Q6ZMV7 3 156825481-157046129 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 12.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 149.4;Ependymal cells: 297.0;Epicardial cells: 143.3;Fallopian tube ciliated cells: 145.8;Late primary spermatocytes: 226.7;Respiratory ciliated cells: 317.6;Thyrotrophs: 116.2" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 143.3;Ciliated cells: 317.6;Spermatogenic cell types: 226.7" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 146.3;ependymal cell: 318.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044039, HPA047774" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm Nucleoli "HPA044039: , HPA047774: " "unprognostic (1.69e-1)" "unprognostic (1.78e-1)" "unprognostic (1.97e-2)" "unprognostic (1.24e-2)" "unprognostic (1.56e-1)" "unprognostic (5.68e-2)" "unprognostic (4.23e-2)" "potential prognostic favorable (5.38e-4)" "unprognostic (1.24e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (2.18e-1)" "unprognostic (3.18e-2)" "unprognostic (3.59e-1)" "unprognostic (7.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.39e-3)" "unprognostic (3.70e-1)" LEMD1 "CT50, LEMP-1" ENSG00000186007 "LEM domain containing 1" Q68G75 1 205381378-205455954 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "epididymis: 14.0;testis: 52.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 6870.8" "Cell type enriched" "Detected in many" 120 "Spermatogenic cell types: 6870.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 47.5;thalamic excitatory: 20.1" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 32.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 18.4" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.1" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 17548 "lymphoid tissue: 1754820.8" HPA076708 Approved "Plasma membrane" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 12 "Plasma membrane" "HPA076708: " "unprognostic (4.00e-2)" "unprognostic (2.30e-1)" "unprognostic (2.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.70e-2)" "unprognostic (2.57e-2)" "unprognostic (6.74e-2)" "unprognostic (3.92e-2)" "unprognostic (3.33e-1)" "unprognostic (5.49e-3)" "unprognostic (6.36e-2)" "unprognostic (1.57e-2)" "unprognostic (8.97e-2)" "unprognostic (6.39e-2)" "unprognostic (1.82e-1)" "unprognostic (1.03e-3)" "unprognostic (1.85e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (6.74e-2)" "unprognostic (2.86e-2)" "unprognostic (3.98e-2)" "unprognostic (2.08e-2)" "unprognostic (4.01e-2)" "unprognostic (1.13e-1)" "unprognostic (1.43e-1)" LEO1 ENSG00000166477 "LEO1 homolog, Paf1/RNA polymerase II complex component" Q8WVC0 15 51938025-51971778 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 236.5;Mast cells: 244.2" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 236.5;Mast cells: 244.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 5898167.6" "HPA040741, HPA040941" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Centrosome" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 58: Mast cells - Allergic inflammatory responses" 43 "Nucleoplasm, Nucleoli fibrillar center" Centrosome "HPA040741: , HPA040941: " "unprognostic (1.33e-1)" "unprognostic (8.34e-2)" "unprognostic (6.04e-2)" "unprognostic (1.93e-2)" "unprognostic (1.79e-1)" "unprognostic (3.10e-2)" "unprognostic (9.10e-2)" "unprognostic (4.39e-3)" "unprognostic (3.64e-2)" "unprognostic (2.60e-2)" "validated prognostic favorable (2.23e-6)" "validated prognostic favorable (2.84e-4)" "unprognostic (1.85e-1)" "unprognostic (4.41e-3)" "unprognostic (8.68e-3)" "unprognostic (1.20e-2)" "unprognostic (2.38e-3)" "unprognostic (1.86e-1)" "unprognostic (2.68e-1)" "unprognostic (1.49e-1)" "unprognostic (1.42e-1)" "unprognostic (3.27e-1)" "unprognostic (8.50e-2)" "unprognostic (2.19e-2)" "unprognostic (1.69e-1)" "unprognostic (5.44e-2)" "unprognostic (3.83e-3)" "unprognostic (1.50e-1)" "unprognostic (1.93e-1)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" LEPR "CD295, OBR" ENSG00000116678 "Leptin receptor" P48357 1 65420652-65641559 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "liver: 121.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 174.1;Fibro-adipogenic progenitors: 188.5;Fibroblasts: 237.9;Gastric chief cells: 252.3;Hepatocytes: 226.1;Parietal cells: 139.7;Podocytes: 204.7;Vascular endothelial cells: 189.8" "Cell type enhanced" "Detected in all" "Fibroblasts: 237.9;Gastric glandular cells: 252.3;Hepatocytes: 226.1" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 132.0;endothelial cell: 493.1;fibroblast: 492.0" "Cancer enriched" "Detected in many" 5 "Liver Hepatocellular Carcinoma (TCGA): 39.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 5.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 5.0" "Low cancer specificity" "Detected in all" "Prostate - Endothelial cells, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 4725 "liver: 472457.4" HPA030899 Approved Supported Approved "Vesicles,Plasma membrane,Primary cilium,Basal body,Cytosol" "Intracellular and membrane" Receptor NA NA 3300000 "Cluster 33: Non-specific - ATP binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 108: Fibroblasts - ECM organization" 7 Vesicles "Plasma membrane, Primary cilium, Basal body, Cytosol" "HPA030899: " "unprognostic (4.19e-1)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-3)" "unprognostic (1.17e-2)" "unprognostic (4.71e-2)" "unprognostic (2.98e-1)" "unprognostic (1.97e-2)" "unprognostic (1.83e-1)" "unprognostic (5.06e-2)" "potential prognostic favorable (5.17e-7)" "unprognostic (3.92e-3)" "unprognostic (1.75e-1)" "unprognostic (2.26e-1)" "unprognostic (3.74e-2)" "unprognostic (1.92e-2)" "unprognostic (2.10e-1)" "unprognostic (4.85e-2)" "unprognostic (4.63e-1)" "unprognostic (1.54e-2)" "unprognostic (2.57e-2)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-1)" "unprognostic (1.66e-1)" "unprognostic (7.42e-2)" "unprognostic (3.69e-1)" "unprognostic (3.10e-2)" "unprognostic (4.15e-2)" LETM2 "FLJ25409, SLC55A2" ENSG00000165046 "Leucine zipper and EF-hand containing transmembrane protein 2" Q2VYF4 8 38386207-38409527 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 13.7;testis: 22.2" "Cell type enhanced" "Detected in many" "Early spermatids: 50.4;Epicardial cells: 175.1;Late primary spermatocytes: 131.6;Late spermatids: 75.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 175.1;Spermatogenic cell types: 131.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 21.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 21.7" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 6 "cerebellum: 32.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA025032 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm "Nuclear bodies, Cytosol" "HPA025032: " "unprognostic (6.36e-2)" "unprognostic (2.00e-1)" "unprognostic (6.90e-2)" "unprognostic (2.20e-2)" "unprognostic (2.08e-1)" "unprognostic (6.13e-3)" "potential prognostic unfavorable (7.45e-5)" "unprognostic (3.58e-1)" "unprognostic (4.73e-2)" "unprognostic (8.62e-3)" "unprognostic (1.20e-2)" "unprognostic (3.29e-1)" "unprognostic (9.53e-2)" "unprognostic (5.35e-1)" "potential prognostic unfavorable (2.21e-5)" "unprognostic (2.49e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-1)" "unprognostic (4.13e-2)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (7.97e-5)" "unprognostic (1.85e-2)" "unprognostic (7.77e-2)" "unprognostic (1.45e-1)" "unprognostic (1.24e-2)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-2)" "unprognostic (8.57e-2)" LFNG SCDO3 ENSG00000106003 "LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q8NES3 7 2512529-2529177 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 71.9;skin 1: 54.9" "Cell type enhanced" "Detected in many" "Astrocytes: 46.2;Basal prostatic cells: 34.9;Bergmann glia: 51.7;Breast myoepithelial cells: 34.4;cDC: 41.3;Goblet cells: 36.8;Mast cells: 32.6;monocytes: 79.2;Müller glia: 39.6;Neuroendocrine cells: 40.0;NK-cells: 32.5;Pancreatic acinar cells: 29.7" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 79.2" "Group enriched" "Detected in many" 6 "astrocyte: 57.6;Bergmann glia: 64.1;endothelial cell: 23.9;fibroblast: 24.0;leukocyte: 55.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Kidney cancer: 108.5" "Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 970 "Smooth muscle cells: 96950.6" "Tissue enriched" "Detected in many" "intestine: 4395096.1" HPA069130 Approved Approved "Nuclear membrane,Golgi apparatus" "Intracellular and membrane" "Developmental protein" NA NA 390000 "Cluster 25: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Nuclear membrane, Golgi apparatus" "HPA069130: " "unprognostic (1.44e-1)" "unprognostic (5.03e-2)" "unprognostic (3.60e-1)" "unprognostic (2.46e-2)" "unprognostic (9.35e-2)" "unprognostic (1.30e-1)" "unprognostic (4.95e-2)" "unprognostic (1.31e-3)" "unprognostic (3.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (9.94e-2)" "unprognostic (1.06e-2)" "unprognostic (4.01e-1)" "unprognostic (1.39e-1)" "unprognostic (6.51e-2)" "unprognostic (1.75e-1)" "unprognostic (2.16e-1)" "unprognostic (4.83e-2)" "unprognostic (2.11e-1)" "unprognostic (2.65e-1)" "unprognostic (2.43e-2)" "unprognostic (7.23e-2)" "unprognostic (1.56e-1)" "unprognostic (5.45e-2)" "unprognostic (5.30e-2)" "unprognostic (8.44e-2)" "unprognostic (5.91e-2)" "unprognostic (4.19e-1)" "unprognostic (7.72e-2)" "unprognostic (2.98e-1)" LGALS1 GBP ENSG00000100097 "Galectin 1" P09382 22 37675636-37679802 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 1781.1;Decidual stromal cells: 10329.3;Endometrial stromal cells: 2107.5;Extravillous trophoblasts: 2291.6;Fibroblasts: 1910.9;Hepatic stellate cells: 6725.9;Hofbauer cells: 2831.6;Melanocytes: 1948.2;Monocyte progenitors: 1860.1;monocytes: 1613.0;Ovarian stromal cells: 2597.2;Pericytes: 1746.4;Schwann cells: 1920.5;Smooth muscle cells: 3074.6" "Cell type enhanced" "Detected in all" "Stellate cells: 6725.9;Stromal cells: 10329.3" "Cell type enhanced" "Detected in all" "pericyte: 504.3;vascular associated smooth muscle cell: 383.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 2024.9" "Cell type enhanced" "Detected in all" "Oocytes: 146887719.6" "Low tissue specificity" "Detected in all" "HPA000646, HPA001130, CAB002157" Enhanced Supported Cytosol "Secreted to blood" Other No Yes 10000000 14000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 74: Non-specific - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 108: Fibroblasts - ECM organization" 89 Cytosol "CAB002157: , HPA000646: , HPA001130: " "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (2.12e-2)" "unprognostic (1.54e-1)" "unprognostic (7.12e-3)" "unprognostic (3.54e-1)" "unprognostic (3.36e-2)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (1.62e-3)" "unprognostic (1.92e-2)" "validated prognostic unfavorable (3.26e-5)" "validated prognostic unfavorable (1.96e-5)" "unprognostic (1.61e-3)" "potential prognostic unfavorable (3.67e-5)" "unprognostic (7.00e-2)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (8.27e-4)" "unprognostic (6.60e-2)" "unprognostic (3.39e-2)" "unprognostic (6.79e-2)" "unprognostic (3.02e-1)" "unprognostic (8.21e-3)" "unprognostic (2.25e-1)" "unprognostic (2.55e-1)" "unprognostic (2.48e-1)" "unprognostic (1.30e-3)" "potential prognostic favorable (4.92e-4)" "unprognostic (8.22e-3)" "unprognostic (8.92e-3)" "unprognostic (8.92e-2)" "unprognostic (1.10e-1)" LGALS2 HL14 ENSG00000100079 "Galectin 2" P05162 22 37570248-37582616 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 315.1;intestine: 186.3;kidney: 142.2;pancreas: 199.3" "Cell type enhanced" "Detected in many" "cDC: 636.9;Cholangiocytes: 577.7;Colonocytes: 755.0;Enteric stem cells: 316.8;Enteric transient amplifying cells: 688.6;Enterocytes: 2372.2;Epididymal efferent duct absorptive cells: 336.7;Gastric progenitor cells: 398.6;Goblet cells: 310.1;Pancreatic acinar cells: 259.8;Paneth cells: 220.4" "Cell type enhanced" "Detected in many" "dendritic cells: 636.9;Ductal cells: 577.7;Enterocytes: 2372.2;Proliferating cells: 688.6" "Cell type enhanced" "Detected in single" "leukocyte: 2.4" "Group enriched" "Detected in all" 4 "Kidney Renal Clear Cell Carcinoma (TCGA): 162.6;Kidney Renal Papillary Cell Carcinoma (TCGA): 123.7;Pancreatic Adenocarcinoma (TCGA): 53.8;Stomach Adenocarcinoma (TCGA): 81.0;Testicular Germ Cell Tumor (TCGA): 46.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 27 "classical monocyte: 1470.6;intermediate monocyte: 555.0;myeloid DC: 1211.4" "Group enriched" "Detected in all" 50 "dendritic cells: 1211.4;monocytes: 1470.6" "Cancer enhanced" "Detected in many" "Gastric cancer: 36.8;liver cancer: 20.7" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Pancreas epithelial cells: 54692083.9;Pancreatic islets: 24500928.4;Proximal tubules: 15037484.1" "Group enriched" "Detected in some" "kidney: 60840613.6;pancreas: 143093460.8" "HPA003536, CAB025198" Enhanced Approved Nucleoplasm,Mitochondria NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 7 Mitochondria Nucleoplasm "CAB025198: , HPA003536: " "unprognostic (2.50e-1)" "unprognostic (6.25e-3)" "unprognostic (5.35e-2)" "unprognostic (4.73e-3)" "unprognostic (1.23e-2)" "unprognostic (4.20e-3)" "unprognostic (1.04e-1)" "unprognostic (6.21e-3)" "unprognostic (1.91e-1)" "validated prognostic favorable (1.85e-10)" "validated prognostic favorable (1.52e-11)" "unprognostic (5.32e-2)" "unprognostic (4.35e-1)" "unprognostic (2.58e-2)" "unprognostic (5.44e-2)" "unprognostic (8.78e-2)" "unprognostic (1.25e-1)" "unprognostic (1.60e-2)" "unprognostic (3.38e-1)" "unprognostic (9.83e-2)" "unprognostic (5.91e-2)" "unprognostic (3.55e-1)" "unprognostic (1.84e-1)" "potential prognostic favorable (4.72e-4)" "unprognostic (1.08e-1)" "unprognostic (2.83e-3)" "unprognostic (3.63e-1)" "unprognostic (1.75e-2)" "unprognostic (6.67e-2)" "unprognostic (2.97e-1)" LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1118.6" "Cell type enhanced" "Detected in many" "Colonocytes: 6455.8;Decidual stromal cells: 2188.3;Enteric transient amplifying cells: 2414.7;Enterocytes: 4003.9;Esophageal apical cells: 3989.9;Ocular epithelial cells: 1947.0;Salivary duct cells: 1971.6" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 3989.9;Enterocytes: 6455.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 129.2;endothelial cell: 145.4;fibroblast: 89.4;vascular associated smooth muscle cell: 69.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 652.7;intermediate monocyte: 545.4;myeloid DC: 398.3;non-classical monocyte: 443.7;T-reg: 252.7" "Group enriched" "Detected in all" 13 "dendritic cells: 398.3;monocytes: 652.7;T-cells: 252.7" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Keratinocytes: 550300178.7;Large ducts: 467510215.8" "Low tissue specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" Immunity NA NA 1800000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 77: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 86 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: , HPA003162: , HPA076528: " "unprognostic (7.29e-2)" "unprognostic (2.02e-1)" "unprognostic (9.10e-2)" "unprognostic (1.73e-1)" "unprognostic (5.97e-2)" "unprognostic (4.11e-2)" "unprognostic (5.90e-3)" "potential prognostic unfavorable (2.47e-6)" "unprognostic (1.27e-1)" "unprognostic (5.26e-2)" "unprognostic (4.83e-3)" "unprognostic (1.34e-1)" "unprognostic (4.38e-1)" "unprognostic (1.26e-3)" "unprognostic (1.09e-1)" "unprognostic (2.27e-3)" "unprognostic (2.76e-2)" "unprognostic (3.24e-3)" "unprognostic (5.62e-2)" "unprognostic (1.39e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-3)" "unprognostic (1.88e-1)" "unprognostic (3.62e-2)" "unprognostic (1.20e-1)" "unprognostic (1.34e-2)" "unprognostic (9.73e-2)" "unprognostic (9.17e-2)" "unprognostic (1.24e-2)" "unprognostic (3.36e-3)" "unprognostic (1.16e-1)" LHFPL3 LHFPL4 ENSG00000187416 "LHFPL tetraspan subfamily member 3" Q86UP9 7 104328603-104908561 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 13.7;retina: 12.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 1598.1;Oligodendrocyte progenitor cells: 4454.9;Rod photoreceptor cells: 2734.9" "Group enriched" "Detected in many" 5 "Glial cells: 4454.9;Neuronal cells: 2734.9" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 4970.5" "Cancer enriched" "Detected in many" 15 "Glioblastoma Multiforme (TCGA): 52.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA069691 Approved Vesicles No NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 38: Sub-cortical - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 2 Vesicles "HPA069691: " "unprognostic (5.65e-2)" "unprognostic (1.60e-1)" "unprognostic (5.93e-2)" "unprognostic (9.88e-2)" "unprognostic (3.70e-2)" "unprognostic (7.26e-2)" "unprognostic (1.36e-1)" "unprognostic (2.42e-1)" "unprognostic (5.43e-2)" "unprognostic (5.35e-2)" "unprognostic (3.65e-1)" "unprognostic (6.80e-3)" LHFPL5 "DFNB67, dJ510O8.8, MGC33835, Tmhs" ENSG00000197753 "LHFPL tetraspan subfamily member 5" Q8TAF8 6 35797206-35845397 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.2;epididymis: 11.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 57.9;Epicardial cells: 59.1;Neutrophils: 91.5;Pancreatic acinar cells: 66.0;Suprabasal keratinocytes: 55.3" "Cell type enhanced" "Detected in many" "Neutrophils: 91.5" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 127.7" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 12.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029421, HPA055110" Uncertain Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 111 Vesicles "HPA029421: , HPA055110: " "unprognostic (1.03e-1)" "unprognostic (9.94e-2)" "unprognostic (9.65e-2)" "unprognostic (3.98e-3)" "unprognostic (3.15e-2)" "unprognostic (9.35e-3)" "unprognostic (3.69e-2)" "potential prognostic unfavorable (2.86e-7)" "unprognostic (8.85e-2)" "unprognostic (3.18e-1)" "unprognostic (7.43e-2)" "unprognostic (5.83e-2)" "unprognostic (1.31e-2)" "unprognostic (3.57e-3)" "unprognostic (3.34e-1)" "unprognostic (8.72e-2)" "unprognostic (2.82e-3)" "unprognostic (4.18e-2)" "potential prognostic favorable (8.01e-4)" "unprognostic (7.86e-3)" "unprognostic (1.02e-2)" "unprognostic (2.59e-1)" "unprognostic (1.65e-1)" "unprognostic (7.67e-2)" LHX1 "LIM-1, LIM1" ENSG00000273706 "LIM homeobox 1" P48742 17 36936785-36944612 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 32.2;kidney: 10.0" "Group enriched" "Detected in some" 5 "Distal convoluted tubule cells: 292.6;Renal collecting duct principal cells: 96.3;Renal connecting tubule cells: 196.8" "Group enriched" "Detected in some" 8 "Ductal cells: 196.8;Renal nephron cells: 292.6" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 54.2;mammillary body: 98.7;upper rhombic lip: 74.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 1.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.5" "Region enhanced" "Detected in many" "cerebellum: 19.1" "Region enriched" "Detected in many" 4 "cerebellum: 21.0" "Group enriched" "Detected in some" 5786 "Collecting ducts: 472091.5;Distal tubules: 685056.5" "Not detected" "Not detected" "HPA044307, HPA073521, HPA074382" Enhanced Approved "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 7 Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA044307: , HPA073521: , HPA074382: " "unprognostic (9.60e-3)" "unprognostic (1.17e-1)" "unprognostic (2.55e-1)" "unprognostic (1.72e-1)" LHX5 ENSG00000089116 "LIM homeobox 5" Q9H2C1 12 113462033-113472280 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "brain: 3.3;stomach 1: 1.3" "Cell type enriched" "Detected in some" 6 "Neuroendocrine cells: 18.7" "Cell type enriched" "Detected in some" 6 "Enteroendocrine cells: 18.7" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 19.3;mammillary body: 6.5;midbrain-derived inhibitory: 7.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "medulla oblongata: 10.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1;head and neck cancer: 1.5" "Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA053908 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 109: Neurons - Neuronal signaling" 17 Cytosol "Nucleoplasm, Nuclear bodies" "HPA053908: " "unprognostic (4.55e-2)" "unprognostic (1.11e-2)" "unprognostic (1.05e-1)" LHX8 Lhx7 ENSG00000162624 "LIM homeobox 8" Q68G74 1 75128434-75161533 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1.4;salivary gland: 1.9" "Cell type enriched" "Detected in some" 19 "Oocytes: 557.2" "Cell type enriched" "Detected in some" 19 "Oocytes: 557.2" "Group enriched" "Detected in some" 5 "ependymal cell: 3.0;splatter: 3.3" "Low cancer specificity" "Detected in some" "Group enriched" "Detected in some" 6 "cerebral cortex: 17.9;hypothalamus: 11.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.1;Neuroblastoma: 4.0" "Minor Salivary Gland - Fibroblasts, Testis - Spermatogonia" "Region enhanced" "Detected in many" "basal ganglia: 9.9" "Region enriched" "Detected in some" 5 "basal ganglia: 15.9" "Cell type enriched" "Detected in single" 6370 "Oocytes: 636965.2" "Not detected" "Not detected" HPA071806 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 33: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 41: Oocytes - Oogenesis" 35 "Nucleoplasm, Nucleoli" Cytosol "HPA071806: " "unprognostic (9.58e-2)" "unprognostic (1.07e-1)" LIAS LAS ENSG00000121897 "Lipoic acid synthetase" O43766 4 39459004-39485109 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 131.2;Late primary spermatocytes: 87.6;Late spermatids: 153.9" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 153.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Cardiomyocytes: 1863301.6;Large ducts: 1783751.9;Proximal tubules: 1941630.9" "Tissue enriched" "Detected in some" "cerebral cortex: 8808289.8" "HPA018842, HPA019076" Approved Supported Approved Nucleoplasm,Mitochondria Yes No "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm Mitochondria "HPA018842: , HPA019076: " "unprognostic (2.68e-2)" "unprognostic (1.22e-2)" "unprognostic (2.09e-1)" "unprognostic (3.63e-2)" "unprognostic (1.31e-1)" "unprognostic (1.49e-1)" "unprognostic (1.51e-1)" "unprognostic (1.88e-2)" "unprognostic (4.47e-2)" "unprognostic (8.43e-2)" "validated prognostic favorable (2.03e-5)" "validated prognostic favorable (4.23e-4)" "unprognostic (3.42e-3)" "unprognostic (7.45e-2)" "unprognostic (3.13e-1)" "unprognostic (1.38e-1)" "unprognostic (1.10e-1)" "unprognostic (9.01e-3)" "unprognostic (4.90e-2)" "unprognostic (3.05e-2)" "unprognostic (1.30e-1)" "unprognostic (1.86e-1)" "unprognostic (1.06e-1)" "unprognostic (5.69e-3)" "unprognostic (9.16e-2)" "potential prognostic favorable (1.24e-4)" "unprognostic (1.53e-1)" "unprognostic (3.96e-2)" "unprognostic (3.72e-1)" "unprognostic (2.66e-2)" "unprognostic (8.28e-3)" LIG1 "hLig1, LIGI" ENSG00000105486 "DNA ligase 1" P18858 19 48115445-48170603 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, DNA replication" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.1;lymphoid tissue: 20.3" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 100.5;Respiratory deuterosomal cells: 59.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 100.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 9308182.6;Neutrophils: 5824043.1" "Tissue enhanced" "Detected in many" "bone marrow: 8932058.3" "CAB037015, HPA041431, HPA048071" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No 3400 "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 10 Nucleoplasm "Golgi apparatus, Vesicles" "CAB037015: , HPA041431: , HPA048071: " "unprognostic (6.89e-2)" "unprognostic (1.38e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" "unprognostic (2.97e-2)" "unprognostic (4.55e-2)" "unprognostic (3.21e-1)" "unprognostic (4.27e-1)" "unprognostic (3.47e-2)" "potential prognostic unfavorable (1.39e-4)" "potential prognostic favorable (3.74e-6)" "unprognostic (1.12e-1)" "unprognostic (3.20e-1)" "unprognostic (1.49e-2)" "unprognostic (2.16e-2)" "unprognostic (4.00e-3)" "unprognostic (7.98e-3)" "unprognostic (2.20e-1)" "unprognostic (3.25e-1)" "unprognostic (1.96e-1)" "unprognostic (3.19e-2)" "unprognostic (2.74e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-2)" "unprognostic (6.72e-2)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (9.15e-4)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" "unprognostic (9.59e-2)" "unprognostic (3.92e-2)" LIMK1 LIMK ENSG00000106683 "LIM domain kinase 1" P53667 7 74082933-74122525 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 87.1" "Cell type enhanced" "Detected in many" "Megakaryocytes: 49.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 4092132.1" "Group enriched" "Detected in some" 33127 "cerebral cortex: 1479684.2;intestine: 5665146.7;lymphoid tissue: 2793380.4" "HPA028516, HPA073571" Approved Supported "Nuclear speckles,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" 22 "Nuclear speckles, Cytosol" "HPA028516: , HPA073571: " "unprognostic (2.77e-1)" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (4.20e-2)" "unprognostic (1.02e-2)" "unprognostic (2.09e-1)" "unprognostic (1.89e-2)" "unprognostic (4.32e-2)" "unprognostic (9.64e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (6.17e-6)" "unprognostic (9.86e-3)" "unprognostic (1.75e-2)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (6.50e-3)" "unprognostic (1.56e-2)" "unprognostic (1.54e-2)" "unprognostic (3.79e-2)" "unprognostic (2.99e-1)" "unprognostic (7.32e-2)" "unprognostic (6.95e-3)" "unprognostic (3.05e-2)" "unprognostic (7.89e-2)" "unprognostic (1.20e-1)" "unprognostic (7.52e-2)" "unprognostic (7.78e-2)" "unprognostic (1.64e-2)" "unprognostic (5.50e-2)" "unprognostic (7.73e-2)" "unprognostic (1.71e-1)" "unprognostic (4.77e-1)" LIMK2 ENSG00000182541 "LIM domain kinase 2" P53671 22 31212239-31280080 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 10 "Neutrophils: 3235.3" "Cell type enriched" "Detected in all" 13 "Neutrophils: 3235.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 40.1;neutrophil: 97.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 97.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1156304.4" "Tissue enriched" "Detected in some" "lymphoid tissue: 1212893.9" "HPA008183, CAB019313, HPA053882" Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 15 Nucleoplasm Cytosol "CAB019313: , HPA008183: , HPA053882: " "unprognostic (3.01e-2)" "unprognostic (2.74e-1)" "unprognostic (1.16e-1)" "unprognostic (2.20e-3)" "unprognostic (1.24e-1)" "unprognostic (3.21e-2)" "unprognostic (1.30e-1)" "unprognostic (6.57e-2)" "unprognostic (9.90e-2)" "unprognostic (7.21e-2)" "unprognostic (5.09e-3)" "unprognostic (5.03e-3)" "unprognostic (1.25e-2)" "unprognostic (2.51e-2)" "unprognostic (2.49e-2)" "unprognostic (6.83e-2)" "unprognostic (1.23e-1)" "unprognostic (4.51e-2)" "unprognostic (1.05e-1)" "unprognostic (3.01e-1)" "unprognostic (5.68e-3)" "unprognostic (2.07e-1)" "unprognostic (4.47e-1)" "unprognostic (1.52e-1)" "unprognostic (6.99e-2)" "unprognostic (1.57e-1)" "unprognostic (1.39e-1)" "unprognostic (1.68e-1)" "unprognostic (3.53e-1)" "unprognostic (3.49e-3)" "unprognostic (2.16e-1)" LIN28A "CSDD1, FLJ12457, LIN-28, LIN28, ZCCHC1" ENSG00000131914 "Lin-28 homolog A" Q9H9Z2 1 26410817-26429728 "Predicted intracellular proteins" "RNA-mediated gene silencing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.9" "Cell type enriched" "Detected in some" 4 "Late spermatids: 111.0" "Cell type enriched" "Detected in some" 48 "Spermatogenic cell types: 111.0" "Cell type enhanced" "Detected in single" "midbrain-derived inhibitory: 1.2" "Cancer enriched" "Detected in some" 85 "Testicular Germ Cell Tumor (TCGA): 334.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 10 "testis cancer: 277.3" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 2943 "Oocytes: 294253.5" "Not detected" "Not detected" "CAB020785, HPA063074, HPA068814" Enhanced Supported "Nucleoli,Cytosol,Rods & Rings" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 250 Cytosol "Nucleoli, Rods & Rings" "CAB020785: , HPA063074: , HPA068814: " "unprognostic (1.82e-2)" "unprognostic (2.33e-1)" "unprognostic (8.97e-2)" "unprognostic (3.69e-2)" "unprognostic (1.04e-1)" LIPA "CESD, LAL" ENSG00000107798 "Lipase A, lysosomal acid type" P38571 10 89213569-89414557 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 375.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 319.2;Kupffer cells: 1525.1;Macrophages: 360.9;Oligodendrocytes: 407.0" "Group enriched" "Detected in all" 4 "Glial cells: 407.0;Mononuclear phagocytes: 1525.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 564.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 167.7;intermediate monocyte: 355.8;myeloid DC: 123.8;non-classical monocyte: 199.7" "Group enriched" "Detected in all" 6 "dendritic cells: 123.8;monocytes: 355.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Skeletal muscle - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 3689157.0;Macrophages: 5806028.3;Pancreatic islets: 8610293.6" "Tissue enriched" "Detected in many" "lymphoid tissue: 26983393.7" "CAB034892, HPA057052" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA 330000 "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Vesicles, Cytosol" "Nucleoplasm, Nucleoli fibrillar center" "CAB034892: , HPA057052: " "unprognostic (2.69e-1)" "unprognostic (1.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.54e-1)" "unprognostic (3.46e-1)" "unprognostic (3.73e-2)" "unprognostic (1.21e-1)" "unprognostic (9.04e-2)" "unprognostic (2.22e-2)" "unprognostic (9.56e-2)" "potential prognostic favorable (6.59e-9)" "unprognostic (3.22e-2)" "unprognostic (5.76e-2)" "unprognostic (1.16e-1)" "unprognostic (3.71e-2)" "unprognostic (5.78e-2)" "unprognostic (3.41e-2)" "unprognostic (3.49e-2)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (3.60e-2)" "unprognostic (3.02e-1)" "unprognostic (2.98e-1)" "unprognostic (3.44e-2)" "unprognostic (6.16e-2)" "unprognostic (4.49e-2)" "unprognostic (1.20e-1)" "unprognostic (2.19e-2)" "unprognostic (4.79e-2)" "unprognostic (3.56e-1)" "unprognostic (6.06e-2)" LIPI "CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5" ENSG00000188992 "Lipase I" Q6XZB0 21 14108813-14210955 "Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 169 "epididymis: 395.8" "Cell type enriched" "Detected in some" 9 "Epididymal principal cells: 497.2" "Cell type enriched" "Detected in many" 9 "Reproductive supporting cells: 497.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 54 "Bone cancer: 22.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA049665 Supported "Plasma membrane" "Secreted in male reproductive system" Enzyme NA NA "Cluster 50: Epididymis - Male reproductive secretion" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" "Plasma membrane" "HPA049665: " LIX1 "C5orf11, Lft" ENSG00000145721 "Limb and CNS expressed 1" Q8N485 5 97091867-97142753 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 25.9;retina: 39.5" "Cell type enhanced" "Detected in some" "Astrocytes: 50.7;B-cells: 20.1;Bergmann glia: 16.7;Epididymal efferent duct absorptive cells: 53.1;Loop of henle epithelial cells: 37.2;Müller glia: 210.0;Pituitary stem cells: 59.7;Retinal amacrine cells: 15.7" "Cell type enhanced" "Detected in many" "Ductal cells: 53.1;Glial cells: 210.0;Renal nephron cells: 37.2;Stem cells: 59.7" "Group enriched" "Detected in many" 4 "astrocyte: 63.8;Bergmann glia: 19.0;ependymal cell: 19.9" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 25.0;Ovary Serous Cystadenocarcinoma (TCGA): 12.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.2" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.4;testis cancer: 28.9" "Colon - Colon enteroendocrine cells, Kidney - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 114778 "Keratinocytes: 11477846.7" "Not detected" "Not detected" HPA058426 Uncertain Approved "Vesicles,Cytokinetic bridge,Cytosol" Yes NA "Cluster 34: B-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 4 Cytosol "Vesicles, Cytokinetic bridge" "HPA058426: " "unprognostic (4.63e-1)" "unprognostic (8.44e-2)" "unprognostic (3.63e-2)" "unprognostic (3.67e-2)" "unprognostic (4.31e-1)" "unprognostic (1.71e-2)" "unprognostic (1.73e-3)" "unprognostic (2.49e-1)" "unprognostic (7.61e-2)" "unprognostic (2.99e-1)" LKAAEAR1 C20orf201 ENSG00000171695 "LKAAEAR motif containing 1" Q8TD35 20 64083376-64084398 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 29.1" "Group enriched" "Detected in some" 7 "Early spermatids: 495.8;Late primary spermatocytes: 312.5;Late spermatids: 890.3" "Cell type enriched" "Detected in many" 11 "Spermatogenic cell types: 890.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.2;Ovary Serous Cystadenocarcinoma (TCGA): 2.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 8.2;non-classical monocyte: 13.0" "Lineage enriched" "Detected in many" 13 "monocytes: 13.0" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA056463 Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Nucleoplasm "HPA056463: " "unprognostic (4.12e-1)" "unprognostic (6.75e-2)" "unprognostic (6.81e-3)" "unprognostic (1.28e-2)" LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 381.9;skeletal muscle: 537.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 479.6;Hepatic stellate cells: 458.3;Myonuclei: 488.6;Pericytes: 218.1;Smooth muscle cells: 1089.9;Thymic myoid cells: 522.1;Vascular endothelial cells: 278.7" "Cell type enhanced" "Detected in many" "Myocytes: 488.6;Smooth muscle cells: 1089.9;Stellate cells: 458.3;Stromal cells: 522.1" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 161.9;endothelial cell: 254.0;vascular associated smooth muscle cell: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.6" "Lineage enriched" "Detected in many" 6 "T-cells: 20.6" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_2, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Skeletal myofibers: 434211042.9;Smooth muscle cells: 376719253.7" "Group enriched" "Detected in all" "blood vessel: 347948217.0;skeletal muscle: 332519735.8" HPA024059 Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 5700 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 27: Breast cancer - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 2 "Nucleoplasm, Plasma membrane" "Cell Junctions, Cytosol" "HPA024059: " "unprognostic (2.76e-2)" "unprognostic (3.21e-1)" "unprognostic (4.21e-2)" "unprognostic (9.28e-2)" "unprognostic (3.11e-3)" "unprognostic (2.56e-2)" "unprognostic (3.20e-2)" "unprognostic (2.83e-2)" "unprognostic (5.49e-2)" "unprognostic (2.52e-2)" "unprognostic (2.12e-3)" "unprognostic (1.64e-2)" "potential prognostic unfavorable (7.86e-4)" "unprognostic (5.99e-2)" "unprognostic (3.27e-1)" "unprognostic (4.93e-1)" "unprognostic (2.06e-1)" "unprognostic (3.44e-2)" "unprognostic (2.95e-1)" "unprognostic (1.44e-2)" "unprognostic (2.09e-1)" "unprognostic (2.32e-1)" "unprognostic (2.04e-2)" "unprognostic (1.58e-2)" "unprognostic (2.67e-2)" "unprognostic (9.75e-3)" "unprognostic (1.97e-1)" "unprognostic (2.10e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (2.45e-1)" LMO4 ENSG00000143013 "LIM domain only 4" P61968 1 87328880-87348923 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 239.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 457.6;Lacrimal acinar cells: 1216.5" "Cell type enhanced" "Detected in all" "Acinar cells: 1216.5" "Cell type enhanced" "Detected in all" "hippocampal CA4: 374.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2041 "ovary: 204077.7" "CAB022345, HPA045877, HPA061638" Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 106 Nucleoplasm "Midbody ring, Cytosol" "CAB022345: , HPA045877: , HPA061638: " "unprognostic (3.11e-1)" "unprognostic (1.66e-1)" "unprognostic (2.47e-1)" "unprognostic (9.18e-2)" "unprognostic (3.42e-1)" "unprognostic (3.50e-2)" "unprognostic (2.38e-1)" "unprognostic (1.66e-3)" "unprognostic (5.07e-3)" "potential prognostic unfavorable (1.21e-5)" "potential prognostic favorable (8.23e-4)" "unprognostic (2.49e-3)" "unprognostic (3.54e-3)" "potential prognostic unfavorable (5.07e-4)" "unprognostic (7.63e-2)" "unprognostic (1.89e-1)" "unprognostic (2.31e-2)" "potential prognostic favorable (5.19e-4)" "unprognostic (1.69e-3)" "unprognostic (2.09e-2)" "unprognostic (1.04e-1)" "unprognostic (7.90e-3)" "unprognostic (1.40e-2)" "unprognostic (6.74e-2)" "unprognostic (8.64e-3)" "unprognostic (8.12e-2)" "unprognostic (5.19e-1)" "unprognostic (8.51e-2)" "unprognostic (4.56e-2)" "unprognostic (6.74e-3)" "unprognostic (6.70e-2)" LMOD1 "1D, 64kD, D1, SM-LMOD, SMLMOD" ENSG00000163431 "Leiomodin 1" P29536 1 201896456-201946588 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 897.6;intestine: 491.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 205.8;Cone photoreceptor cells: 455.4;Decidual stromal cells: 194.1;Hepatic stellate cells: 193.6;Leydig cells: 249.6;Pericytes: 320.7;Peritubular myoid cells: 413.2;Rod photoreceptor cells: 253.3;Salivary myoepithelial cells: 167.0;Smooth muscle cells: 698.6;Vascular smooth muscle cells: 812.0" "Cell type enhanced" "Detected in many" "Mural cells: 812.0;Neuronal cells: 455.4;Smooth muscle cells: 698.6;Stromal cells: 413.2" "Cell type enriched" "Detected in many" 5 "vascular associated smooth muscle cell: 416.3" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 64.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 8.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 209816156.0" "Tissue enhanced" "Detected in many" "blood vessel: 208220975.4" "HPA028325, HPA028435, HPA030097" Enhanced Approved Cytosol No No "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Cytosol "HPA028325: , HPA028435: , HPA030097: " "unprognostic (2.84e-3)" "unprognostic (2.10e-2)" "unprognostic (4.51e-1)" "unprognostic (2.59e-1)" "unprognostic (2.33e-2)" "unprognostic (1.11e-2)" "unprognostic (1.74e-1)" "unprognostic (2.87e-1)" "unprognostic (1.14e-1)" "unprognostic (1.84e-2)" "validated prognostic favorable (3.87e-4)" "validated prognostic favorable (1.24e-4)" "potential prognostic unfavorable (1.34e-6)" "potential prognostic favorable (1.01e-5)" "unprognostic (1.00e-2)" "unprognostic (1.42e-1)" "unprognostic (4.49e-1)" "unprognostic (6.11e-3)" "unprognostic (5.86e-2)" "unprognostic (2.84e-3)" "unprognostic (4.42e-3)" "unprognostic (3.47e-1)" "unprognostic (1.85e-3)" "unprognostic (9.01e-2)" "unprognostic (4.78e-2)" "unprognostic (1.58e-2)" "unprognostic (4.92e-2)" "unprognostic (2.29e-2)" "unprognostic (1.70e-1)" "unprognostic (5.01e-3)" "unprognostic (5.14e-3)" LMX1B NPS1 ENSG00000136944 "LIM homeobox transcription factor 1 beta" O60663 9 126613928-126701032 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 17.5" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 23.5;Breast myoepithelial cells: 29.3;Breast secretory cells: 19.0;Lacrimal acinar cells: 77.9;Podocytes: 268.7;Salivary acinar cells: 58.4;Salivary myoepithelial cells: 18.4" "Group enriched" "Detected in many" 5 "Acinar cells: 77.9;Renal nephron cells: 268.7" "Group enriched" "Detected in some" 5 "ependymal cell: 14.6;splatter: 13.4" "Cancer enriched" "Detected in some" 14 "Breast Invasive Carcinoma (TCGA): 18.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 6.5;Rhabdoid: 7.4" "Colon - Enteric glia cells, Kidney - Podocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Pituitary gland - Gonadotropes, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Region enhanced" "Detected in some" "pons and medulla: 2.3" "Region enhanced" "Detected in many" "midbrain: 5.8" "Cell type enriched" "Detected in single" 2864 "Glomeruli: 286356.0" "Not detected" "Not detected" "HPA073716, HPA075656" Approved Nucleoplasm NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 6 Nucleoplasm "HPA073716: , HPA075656: " "unprognostic (3.71e-1)" "unprognostic (1.57e-1)" "unprognostic (1.33e-1)" "unprognostic (1.40e-1)" LONP1 "hLON, LonHS, PIM1, PRSS15" ENSG00000196365 "Lon peptidase 1, mitochondrial" P36776 19 5691834-5720572 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA-binding, Hydrolase, Protease, Serine protease" "Cataract, Deafness, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 190.0" "Cell type enhanced" "Detected in many" "Epicardial cells: 118.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA002034, HPA002192" Supported Supported Nucleoplasm,Mitochondria,Cytosol No No 52000 "Cluster 18: Non-specific - Translation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 65: Non-specific - Cell growth & division" 84 Mitochondria "Nucleoplasm, Cytosol" "HPA002034: , HPA002192: " "unprognostic (1.30e-2)" "unprognostic (9.59e-2)" "unprognostic (3.97e-1)" "unprognostic (2.05e-1)" "unprognostic (3.61e-1)" "unprognostic (3.51e-1)" "unprognostic (4.10e-2)" "unprognostic (3.59e-2)" "unprognostic (2.61e-2)" "unprognostic (1.74e-2)" "unprognostic (2.63e-1)" "unprognostic (1.13e-1)" "unprognostic (2.32e-1)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (3.34e-3)" "unprognostic (1.50e-1)" "unprognostic (4.72e-3)" "unprognostic (3.68e-3)" "unprognostic (1.49e-2)" "unprognostic (1.53e-1)" "unprognostic (3.35e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (2.39e-1)" "unprognostic (3.60e-3)" "unprognostic (2.13e-1)" "unprognostic (1.82e-2)" "unprognostic (7.18e-3)" "unprognostic (1.21e-1)" "unprognostic (3.13e-2)" LOXHD1 "DFNB77, FLJ32670, LH2D1" ENSG00000167210 "Lipoxygenase homology PLAT domains 1" Q8IVV2 18 46476972-46657220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 6.8;testis: 21.5" "Cell type enhanced" "Detected in some" "Early spermatids: 365.4;Lactotrophs: 74.4;Late primary spermatocytes: 89.8;Late spermatids: 1054.5;Mesothelial cells: 72.2;Neutrophil progenitors: 147.6;Neutrophils: 199.7;Thyrotrophs: 98.5" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 1054.5" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 53.4;medium spiny neuron: 51.1" "Group enriched" "Detected in some" 5 "Kidney Chromophobe (TCGA): 1.8;Testicular Germ Cell Tumor (TCGA): 1.9" "Region enhanced" "Detected in many" "basal ganglia: 7.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 38 "Bone cancer: 49.3" "Pituitary gland - Lactotropes, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 2373 "Fallopian tube cells: 237285.6" "Tissue enriched" "Detected in single" 7255 "lymphoid tissue: 725544.2" HPA077128 Approved "Plasma membrane" NA NA "Cluster 22: Epididymis - Mixed function" "Cluster 33: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Plasma membrane" "HPA077128: " "unprognostic (6.30e-3)" "unprognostic (2.42e-1)" "unprognostic (1.20e-1)" LOXL1 "LOL, LOXL" ENSG00000129038 "Lysyl oxidase like 1" Q08397 15 73925989-73952137 "Disease related genes, Plasma proteins, Predicted secreted proteins" Oxidoreductase Glaucoma "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 67.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 164.7;Extravillous trophoblasts: 245.8;Fibroblasts: 60.4;Hepatic stellate cells: 213.0;Podocytes: 58.8;Retinal pigment epithelial cells: 85.3;Smooth muscle cells: 53.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 164.7;Stellate cells: 213.0;Trophoblast cells: 245.8" "Group enriched" "Detected in many" 6 "choroid plexus epithelial cell: 120.7;fibroblast: 31.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 26.2" "Immune cell enhanced" "Detected in some" "T-reg: 3.4" "Lineage enriched" "Detected in single" 34 "T-cells: 3.4" "Cancer enhanced" "Detected in many" "Brain cancer: 89.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Liver - Hepatic stellate cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Smooth muscle cells: 55776221.7" "Tissue enriched" "Detected in many" "blood vessel: 63106229.6" "HPA042111, HPA063583" Approved Approved "Endoplasmic reticulum" "Secreted to extracellular matrix" Enzyme No No 130000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 "Endoplasmic reticulum" "HPA042111: , HPA063583: " "unprognostic (1.44e-2)" "unprognostic (8.54e-2)" "unprognostic (2.26e-1)" "unprognostic (4.83e-3)" "unprognostic (1.92e-2)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (2.00e-4)" "validated prognostic unfavorable (2.00e-4)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "validated prognostic unfavorable (3.76e-5)" "validated prognostic unfavorable (1.57e-4)" "unprognostic (9.91e-3)" "unprognostic (1.60e-1)" "unprognostic (2.08e-2)" "unprognostic (2.94e-2)" "unprognostic (1.19e-1)" "unprognostic (3.24e-1)" "unprognostic (1.43e-1)" "unprognostic (5.60e-2)" "unprognostic (3.59e-2)" "unprognostic (1.58e-1)" "unprognostic (2.29e-1)" "unprognostic (1.52e-1)" "unprognostic (2.87e-1)" "unprognostic (2.70e-2)" "unprognostic (3.46e-2)" "unprognostic (4.63e-2)" "unprognostic (2.25e-2)" "unprognostic (2.34e-3)" "unprognostic (4.63e-1)" LOXL2 "LOR, WS9-14" ENSG00000134013 "Lysyl oxidase like 2" Q9Y4K0 8 23296897-23425328 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Transcription, Transcription regulation" "Chromatin regulator, Oxidoreductase, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 38.5" "Cell type enhanced" "Detected in many" "Adipocytes: 77.1;Breast myoepithelial cells: 71.5;Endometrial stromal cells: 72.4;Fibro-adipogenic progenitors: 76.0;Fibroblasts: 72.6;Hepatic stellate cells: 264.6;Oocytes: 322.4;Ovarian stromal cells: 99.1;Pericytes: 117.7;Smooth muscle cells: 101.7;Vascular endothelial cells: 93.8" "Cell type enhanced" "Detected in many" "Oocytes: 322.4;Stellate cells: 264.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Kidney cancer: 665.7" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 29506 "Oocytes: 2950595.2" "Tissue enriched" "Detected in single" 6942 "blood vessel: 694179.1" "CAB025848, HPA036257, HPA056542" Approved Enhanced Nucleoplasm "Secreted to extracellular matrix" Transcription NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 41 Nucleoplasm "CAB025848: , HPA036257: , HPA056542: " "unprognostic (1.49e-1)" "unprognostic (1.73e-1)" "unprognostic (2.53e-2)" "potential prognostic unfavorable (4.72e-4)" "unprognostic (3.63e-2)" "unprognostic (6.19e-2)" "unprognostic (8.40e-3)" "unprognostic (1.29e-1)" "unprognostic (2.95e-2)" "unprognostic (4.10e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (2.56e-2)" "unprognostic (2.24e-3)" "unprognostic (1.40e-1)" "validated prognostic unfavorable (9.74e-7)" "validated prognostic unfavorable (1.68e-5)" "unprognostic (3.81e-3)" "unprognostic (3.28e-3)" "unprognostic (1.48e-3)" "potential prognostic unfavorable (4.38e-4)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (1.48e-1)" "unprognostic (2.69e-1)" "unprognostic (3.28e-1)" "unprognostic (8.33e-2)" "unprognostic (1.59e-1)" "unprognostic (3.61e-2)" "unprognostic (1.67e-1)" "unprognostic (7.36e-3)" "unprognostic (2.00e-1)" LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2885296-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 141.2" "Cell type enhanced" "Detected in all" "Foveolar cells: 385.3;Microglia: 333.7" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 422.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 6 "granulocytes: 32.0;NK-cells: 13.3;T-cells: 12.0" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 3185891.5;Glomeruli: 3130944.6;Granulosa cells: 6983135.6" "Low tissue specificity" "Detected in many" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 4 Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: , HPA030550: " "unprognostic (1.94e-1)" "unprognostic (1.52e-1)" "unprognostic (8.36e-2)" "unprognostic (2.09e-1)" "unprognostic (6.32e-2)" "unprognostic (1.16e-3)" "unprognostic (2.91e-1)" "unprognostic (8.27e-3)" "potential prognostic favorable (5.62e-4)" "unprognostic (1.33e-2)" "potential prognostic favorable (6.85e-5)" "unprognostic (2.74e-3)" "unprognostic (1.47e-1)" "unprognostic (2.24e-3)" "unprognostic (1.33e-1)" "unprognostic (4.75e-2)" "unprognostic (2.39e-2)" "unprognostic (9.05e-3)" "unprognostic (2.43e-1)" "unprognostic (3.16e-3)" "unprognostic (3.81e-3)" "unprognostic (4.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.11e-1)" "unprognostic (4.78e-2)" "unprognostic (2.77e-1)" "unprognostic (9.61e-3)" "unprognostic (1.99e-1)" "unprognostic (4.86e-1)" "unprognostic (1.30e-1)" "unprognostic (6.73e-3)" LPXN LDPL ENSG00000110031 Leupaxin O60711 11 58526871-58578220 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 111.0" "Cell type enhanced" "Detected in many" "cDC: 190.7;Innate lymphoid cells: 348.1;Macrophages: 191.6;Mast cells: 181.6;monocytes: 366.5;pDCs: 296.2;Plasma cells: 184.0;T-cells: 165.9" "Cell type enhanced" "Detected in all" "dendritic cells: 296.2;Innate lymphoid cells: 348.1;Mononuclear phagocytes: 366.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 167.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 180.9" "Breast - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 14571062.6;Macrophages: 4615862.4;T-cells: 14211255.0" "Tissue enriched" "Detected in many" "lymphoid tissue: 9134355.6" "HPA043741, CAB046478, HPA061441" Enhanced Supported "Nuclear speckles,Focal adhesion sites,Cytosol" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 20 "Focal adhesion sites" "Nuclear speckles, Cytosol" "CAB046478: , HPA043741: , HPA061441: " "unprognostic (5.26e-3)" "unprognostic (4.26e-3)" "unprognostic (5.51e-2)" "unprognostic (1.84e-1)" "unprognostic (2.70e-1)" "unprognostic (1.01e-1)" "unprognostic (1.99e-1)" "unprognostic (1.91e-2)" "unprognostic (7.51e-3)" "unprognostic (9.15e-2)" "unprognostic (1.64e-1)" "unprognostic (1.83e-1)" "unprognostic (9.01e-3)" "unprognostic (9.56e-3)" "unprognostic (1.03e-2)" "potential prognostic favorable (3.74e-4)" "unprognostic (3.52e-2)" "unprognostic (1.07e-1)" "unprognostic (2.58e-1)" "unprognostic (1.77e-1)" "unprognostic (5.49e-2)" "unprognostic (3.06e-2)" "unprognostic (2.25e-2)" "unprognostic (1.71e-1)" "unprognostic (2.12e-1)" "unprognostic (1.79e-2)" "unprognostic (6.47e-2)" "unprognostic (9.75e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-1)" "unprognostic (3.85e-2)" LRAT LCA14 ENSG00000121207 "Lecithin retinol acyltransferase" O95237 4 154626945-154753120 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sensory transduction, Vision" "Acyltransferase, Transferase" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;liver: 2.0" "Cell type enriched" "Detected in many" 12 "Retinal pigment epithelial cells: 1956.7" "Cell type enriched" "Detected in many" 12 "Pigment cells: 1956.7" "Group enriched" "Detected in many" 5 "astrocyte: 62.5;choroid plexus epithelial cell: 85.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Alveolar cells type 2, Skin - Hair cortex cells, Skin - Outer root sheath cells, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 6283 "Granulosa cells: 628293.9" "Not detected" "Not detected" HPA070726 Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Basal body" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 3 "Endoplasmic reticulum, Golgi apparatus" "Plasma membrane, Basal body" "HPA070726: " "unprognostic (2.23e-1)" "unprognostic (1.87e-1)" "unprognostic (4.95e-2)" "unprognostic (2.04e-1)" "unprognostic (2.46e-1)" "unprognostic (3.32e-2)" "unprognostic (2.60e-2)" "unprognostic (6.11e-2)" LRATD1 "FAM84A, FLJ35392, NSE1" ENSG00000162981 "LRAT domain containing 1" Q96KN4 2 14632700-14650814 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 30.4;intestine: 38.4" "Cell type enhanced" "Detected in many" "Colonocytes: 171.1;Cytotrophoblasts: 198.5;Enteric stem cells: 203.7;Enteric transient amplifying cells: 158.1;Epididymal principal cells: 187.8;Esophageal apical cells: 184.9;Esophageal suprabasal cells: 163.4;Goblet cells: 118.8;Migrating cytotrophoblasts: 120.3;Prostatic glandular cells: 125.4;Syncytiotrophoblasts: 222.4;Urothelial cells: 220.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 220.0;Stem cells: 203.7;Trophoblast cells: 222.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 52.2" "Adipose subcutaneous - Smooth muscle cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 72385.2" "Group enriched" "Detected in some" 22 "cerebral cortex: 1988.9;salivary gland: 2416.4" HPA047703 Uncertain Approved Nucleoplasm NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Nucleoplasm "HPA047703: " "unprognostic (6.67e-2)" "unprognostic (2.72e-2)" "unprognostic (5.28e-2)" "unprognostic (2.04e-2)" "potential prognostic favorable (9.29e-5)" "unprognostic (1.09e-1)" "unprognostic (1.40e-3)" "unprognostic (2.03e-1)" "unprognostic (7.97e-2)" "potential prognostic favorable (2.43e-5)" "unprognostic (2.70e-2)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (2.10e-1)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (1.86e-2)" "unprognostic (7.52e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (5.57e-2)" "potential prognostic favorable (7.28e-5)" "unprognostic (1.07e-1)" "unprognostic (3.48e-2)" "unprognostic (6.14e-2)" "unprognostic (1.48e-1)" "unprognostic (9.93e-2)" "unprognostic (1.04e-1)" LRCH3 MGC4126 ENSG00000186001 "Leucine rich repeats and calponin homology domain containing 3" Q96II8 3 197791226-197888436 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 39.0" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 2102770.9;Neutrophils: 2255640.0" "Tissue enhanced" "Detected in many" "lymphoid tissue: 5804574.4" "HPA012380, HPA017299" Uncertain Enhanced Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 28 Cytosol "HPA012380: , HPA017299: " "unprognostic (3.62e-2)" "unprognostic (7.49e-3)" "unprognostic (3.07e-2)" "unprognostic (2.97e-3)" "unprognostic (4.98e-2)" "unprognostic (1.16e-1)" "unprognostic (1.40e-1)" "unprognostic (4.95e-3)" "unprognostic (8.71e-2)" "unprognostic (1.23e-2)" "unprognostic (2.28e-2)" "unprognostic (4.02e-3)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (1.65e-4)" "unprognostic (1.46e-1)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (6.02e-4)" "unprognostic (2.19e-1)" "unprognostic (1.62e-1)" "unprognostic (2.98e-3)" "unprognostic (6.92e-2)" "unprognostic (1.08e-1)" "unprognostic (8.23e-3)" "unprognostic (2.83e-2)" "unprognostic (4.68e-2)" "unprognostic (2.52e-1)" "unprognostic (9.51e-2)" "unprognostic (1.69e-1)" "unprognostic (1.20e-1)" "unprognostic (7.88e-2)" "unprognostic (1.44e-1)" LRG1 LRG ENSG00000171236 "Leucine rich alpha-2-glycoprotein 1" P02750 19 4536402-4540036 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 20 "liver: 1004.2" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 1.9;Fallopian secretory cells: 1.6;Fallopian tube ciliated cells: 6.2;Hepatocytes: 3.8;Neutrophils: 5.9;Pancreatic duct cells: 1.4;Prostatic hillock cells: 1.3;Salivary acinar cells: 1.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 6.2;Hepatocytes: 3.8;Neutrophils: 5.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 226.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 19 "neutrophil: 285.0" "Lineage enriched" "Detected in many" 45 "granulocytes: 285.0" "Low cancer specificity" "Detected in many" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Kidney - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in single" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA001888, HPA001889" Enhanced Approved Vesicles "Secreted to blood" "No annotated function" NA NA 21000000000 12000000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 Vesicles "HPA001888: , HPA001889: " "unprognostic (8.36e-2)" "unprognostic (3.04e-2)" "unprognostic (2.71e-1)" "unprognostic (2.48e-1)" "unprognostic (4.79e-2)" "unprognostic (8.46e-2)" "unprognostic (2.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.63e-1)" "unprognostic (6.28e-3)" "unprognostic (7.05e-2)" "unprognostic (2.69e-3)" "unprognostic (4.77e-2)" "potential prognostic favorable (2.39e-4)" "unprognostic (5.74e-2)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (3.26e-2)" "unprognostic (9.12e-2)" "unprognostic (3.77e-2)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (1.02e-1)" "unprognostic (1.87e-1)" "unprognostic (3.09e-1)" "unprognostic (1.06e-2)" "unprognostic (1.68e-1)" "unprognostic (8.62e-2)" "unprognostic (1.10e-1)" "unprognostic (2.35e-3)" "unprognostic (1.62e-2)" LRIF1 "C1orf103, FLJ11269, RIF1" ENSG00000121931 "Ligand dependent nuclear receptor interacting factor 1" Q5T3J3 1 110947190-110963965 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 150.4;Epididymal principal cells: 188.4;Neutrophils: 138.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 87199.4;Fallopian tube cells: 52765.5;Neutrophils: 65765.3" "Tissue enriched" "Detected in single" 7705 "lymphoid tissue: 770489.4" HPA044515 Uncertain Supported "Nucleoplasm,Centriolar satellite" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 75: Non-specific - Chaperones and protein folding" 39 Nucleoplasm "Centriolar satellite" "HPA044515: " "unprognostic (2.77e-1)" "unprognostic (1.48e-1)" "unprognostic (3.82e-2)" "unprognostic (7.39e-2)" "unprognostic (1.77e-1)" "unprognostic (2.82e-2)" "unprognostic (6.20e-2)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (7.62e-4)" "potential prognostic favorable (3.09e-5)" "unprognostic (4.82e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.40e-3)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (1.63e-1)" "unprognostic (2.94e-3)" "unprognostic (6.09e-2)" "unprognostic (2.07e-3)" "unprognostic (1.80e-1)" "unprognostic (7.85e-2)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (1.73e-1)" "unprognostic (3.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.93e-1)" "unprognostic (1.84e-1)" "unprognostic (1.67e-1)" "unprognostic (1.57e-2)" "unprognostic (3.40e-1)" LRPPRC "GP130, LRP130, LSFC" ENSG00000138095 "Leucine rich pentatricopeptide repeat containing" P42704 2 43886224-43996226 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Autophagy, mRNA transport, Transcription, Transcription regulation, Transport" "DNA-binding, RNA-binding" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB033786, HPA036408, HPA036409" Enhanced Enhanced "Mitochondria,Acrosome,Mid piece,End piece" No No 290000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 92 Mitochondria "Acrosome, Mid piece, End piece" "CAB033786: , HPA036408: , HPA036409: " "unprognostic (7.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.45e-1)" "unprognostic (1.94e-1)" "unprognostic (5.14e-2)" "unprognostic (7.66e-2)" "unprognostic (3.51e-1)" "unprognostic (1.26e-1)" "unprognostic (8.75e-2)" "unprognostic (7.23e-3)" "potential prognostic favorable (6.12e-7)" "unprognostic (5.39e-3)" "unprognostic (3.41e-1)" "validated prognostic unfavorable (1.22e-5)" "validated prognostic unfavorable (1.47e-5)" "unprognostic (3.79e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (4.56e-3)" "unprognostic (3.91e-2)" "unprognostic (1.43e-1)" "unprognostic (7.88e-2)" "unprognostic (1.35e-2)" "unprognostic (6.40e-2)" "unprognostic (5.39e-2)" "unprognostic (3.12e-2)" "unprognostic (6.13e-2)" "unprognostic (2.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.53e-1)" "unprognostic (6.69e-3)" "unprognostic (1.87e-2)" LRR1 "LRR-1, MGC20689, PPIL5" ENSG00000165501 "Leucine rich repeat protein 1" Q96L50 14 49598761-49614672 "Essential proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 27.2" "Cell type enhanced" "Detected in many" "Early spermatids: 103.9;Erythrocyte progenitors: 68.7;Late primary spermatocytes: 345.6;Late spermatids: 52.9" "Cell type enriched" "Detected in all" 5 "Spermatogenic cell types: 345.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 9.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 241 "cerebral cortex: 24108.9" "HPA065703, HPA069364" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 17 "Nucleoplasm, Nuclear membrane" Vesicles "HPA065703: , HPA069364: " "unprognostic (8.03e-2)" "unprognostic (1.19e-2)" "unprognostic (2.01e-1)" "unprognostic (1.55e-3)" "unprognostic (1.16e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (9.94e-2)" "potential prognostic unfavorable (9.29e-7)" "unprognostic (5.74e-3)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (6.87e-7)" "unprognostic (2.07e-3)" "unprognostic (3.50e-2)" "unprognostic (2.01e-3)" "unprognostic (1.74e-1)" "unprognostic (8.39e-2)" "unprognostic (3.78e-2)" "unprognostic (1.01e-2)" "unprognostic (4.91e-3)" "unprognostic (7.40e-2)" "unprognostic (1.79e-1)" "unprognostic (2.05e-2)" "unprognostic (4.10e-2)" "unprognostic (8.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.76e-1)" "unprognostic (1.08e-1)" LRRC10B ENSG00000204950 "Leucine rich repeat containing 10B" A6NIK2 11 61508749-61511018 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.2;fallopian tube: 27.0;pituitary gland: 31.9" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 56.9;Ependymal cells: 32.4;Epididymal efferent duct ciliated cells: 49.5;Fallopian tube ciliated cells: 179.1;Pancreatic islet cells: 32.8;Respiratory ciliated cells: 225.3;Vascular smooth muscle cells: 38.3" "Cell type enriched" "Detected in some" 5 "Ciliated cells: 225.3" "Cell type enhanced" "Detected in many" "ependymal cell: 37.9;medium spiny neuron: 20.7;vascular associated smooth muscle cell: 24.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 7.4" "Region enhanced" "Detected in many" "basal ganglia: 90.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 4.0;Sarcoma: 3.6" "Heart muscle - Smooth muscle cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Pituitary gland - Somatotropes, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 7 "basal ganglia: 222.6" "Group enriched" "Detected in many" 5 "basal ganglia: 40.7;hippocampal formation: 31.6" "Cell type enriched" "Detected in single" 1357 "Smooth muscle cells: 135732.4" "Tissue enriched" "Detected in single" 7498 "ovary: 749779.6" HPA047619 Uncertain Approved Nucleoplasm,Nucleoli No NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" Nucleoplasm Nucleoli "HPA047619: " "unprognostic (1.05e-1)" "unprognostic (6.40e-2)" "unprognostic (1.39e-3)" "unprognostic (4.36e-2)" "unprognostic (9.86e-2)" "unprognostic (2.22e-1)" "unprognostic (2.42e-3)" "unprognostic (6.19e-2)" "potential prognostic favorable (6.64e-4)" "unprognostic (2.36e-3)" "unprognostic (1.95e-1)" "unprognostic (3.08e-2)" "unprognostic (2.31e-1)" "unprognostic (1.88e-2)" "unprognostic (1.53e-2)" "unprognostic (1.73e-1)" "unprognostic (6.74e-2)" "unprognostic (1.81e-2)" "unprognostic (7.64e-2)" "unprognostic (6.26e-2)" LRRC14B ENSG00000185028 "Leucine rich repeat containing 14B" A6NHZ5 5 191495-196334 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 4 "heart muscle: 39.2;skeletal muscle: 106.6" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 9.6;Myonuclei: 14.7;Oocytes: 4.6;Retinal ganglion cells: 11.6;Retinal horizontal cells: 6.0" "Group enriched" "Detected in some" 4 "Myocytes: 14.7;Neuronal cells: 11.6;Oocytes: 4.6" "Cell type enhanced" "Detected in single" "mammillary body: 1.6" "Cancer enriched" "Detected in some" 21 "Kidney Chromophobe (TCGA): 26.7" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.6" "Group enriched" "Detected in some" 16 "Leukemia: 9.4;lymphoma: 5.8;Myeloma: 16.2" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Capillaries: 3496909.7;Cardiomyocytes: 5578068.3;Skeletal myofibers: 1765798.3" "Tissue enriched" "Detected in some" "heart muscle: 979741.8" "HPA038046, HPA038047" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 55: Myocytes - Oxidative muscle function" "Nucleoplasm, Cytosol" "HPA038046: , HPA038047: " "potential prognostic unfavorable (4.55e-4)" "unprognostic (3.02e-1)" "unprognostic (7.30e-2)" "unprognostic (5.90e-3)" LRRC17 "H_RG318M05.3, P37NB" ENSG00000128606 "Leucine rich repeat containing 17" Q8N6Y2 7 102913000-102945111 "Predicted secreted proteins" Osteogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 92.6" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 201.0;Epicardial cells: 63.7;Gastric chief cells: 146.3;Granulosa cells: 72.2;Hepatic stellate cells: 71.0;Leydig cells: 103.1;Mucous neck cells: 57.1;Oocytes: 64.5;Ovarian stromal cells: 181.9;Parietal cells: 60.1" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 146.3;Goblet cells: 201.0;Leydig cells: 103.1;Stromal cells: 181.9" "Cell type enhanced" "Detected in all" "endothelial cell: 77.6;fibroblast: 81.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 21.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "eosinophil: 9.9" "Lineage enriched" "Detected in single" 94 "granulocytes: 9.9" "Cancer enhanced" "Detected in many" "Brain cancer: 51.0;Sarcoma: 69.5" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_2, Minor Salivary Gland - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Chief cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Fallopian tube cells: 1507294.9;Smooth muscle cells: 5625253.0" "Group enriched" "Detected in many" "blood vessel: 5918092.3;skin: 8065714.2" HPA073458 Approved "Vesicles,Cytokinetic bridge" "Secreted in other tissues" Other Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 94: Gonadal somatic cells - Mixed function" 9 Vesicles "Cytokinetic bridge" "HPA073458: " "unprognostic (2.85e-1)" "unprognostic (3.86e-1)" "unprognostic (1.35e-1)" "unprognostic (1.46e-1)" "unprognostic (5.07e-2)" "unprognostic (2.18e-1)" "unprognostic (3.99e-1)" "unprognostic (3.47e-1)" "unprognostic (2.69e-1)" "unprognostic (6.14e-2)" "unprognostic (2.82e-3)" "potential prognostic favorable (9.55e-4)" "unprognostic (8.38e-3)" "unprognostic (9.91e-2)" "unprognostic (1.49e-1)" "unprognostic (8.92e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-2)" "unprognostic (4.28e-2)" "unprognostic (9.49e-3)" "unprognostic (2.33e-2)" "unprognostic (2.01e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "unprognostic (1.62e-1)" "unprognostic (7.00e-2)" "unprognostic (1.71e-3)" "unprognostic (3.73e-2)" "unprognostic (1.38e-2)" "unprognostic (2.70e-1)" LRRC20 "FLJ10751, FLJ10844" ENSG00000172731 "Leucine rich repeat containing 20" Q8TCA0 10 70298970-70382650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 286.3;tongue: 116.7" "Cell type enhanced" "Detected in many" "Early spermatids: 39.1;Esophageal apical cells: 101.2;Gonadotrophs: 43.6;Late primary spermatocytes: 61.6;Late spermatids: 91.0;Myonuclei: 111.8;Somatotrophs: 38.3;Thyrotrophs: 46.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 101.2;Myocytes: 111.8;Spermatogenic cell types: 91.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Pituitary gland - Gonadotropes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 62423499.5" "Tissue enriched" "Detected in all" "skeletal muscle: 110451633.2" HPA039630 Approved Nucleoplasm,Cytosol No No "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 Nucleoplasm Cytosol "HPA039630: " "unprognostic (5.60e-3)" "unprognostic (2.68e-2)" "unprognostic (5.93e-2)" "unprognostic (1.01e-2)" "unprognostic (1.28e-1)" "unprognostic (3.11e-1)" "unprognostic (4.10e-2)" "potential prognostic favorable (2.91e-4)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (3.16e-4)" "unprognostic (2.19e-1)" "unprognostic (4.62e-3)" "potential prognostic favorable (3.53e-6)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-1)" "unprognostic (9.50e-3)" "unprognostic (2.53e-1)" "unprognostic (2.85e-1)" "unprognostic (1.20e-1)" "unprognostic (1.01e-1)" "unprognostic (5.37e-2)" "unprognostic (1.80e-1)" "unprognostic (1.00e-1)" "unprognostic (6.00e-2)" "unprognostic (3.28e-1)" "unprognostic (1.27e-3)" "unprognostic (1.07e-1)" "unprognostic (6.03e-2)" "unprognostic (1.98e-2)" LRRC28 "FLJ34269, FLJ45242, MGC24976" ENSG00000168904 "Leucine rich repeat containing 28" Q86X40 15 99251362-99390729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 44.0" "Cell type enhanced" "Detected in many" "Late spermatids: 635.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 635.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 110067.5;Hepatocytes: 57408.6;Neurons: 104908.9" "Group enriched" "Detected in some" 30 "intestine: 1912.5;liver: 4079.0" "HPA039378, HPA040784, HPA066130" Approved Approved "Nucleoplasm,Golgi apparatus,Mitochondria" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 3 Nucleoplasm "Golgi apparatus, Mitochondria" "HPA039378: , HPA040784: , HPA066130: " "unprognostic (2.06e-1)" "unprognostic (1.29e-1)" "unprognostic (2.78e-1)" "unprognostic (2.45e-1)" "unprognostic (6.26e-2)" "unprognostic (6.20e-2)" "unprognostic (1.45e-2)" "unprognostic (2.38e-1)" "unprognostic (5.62e-3)" "unprognostic (1.01e-1)" "validated prognostic favorable (4.76e-10)" "validated prognostic favorable (6.95e-4)" "unprognostic (2.55e-1)" "unprognostic (1.71e-1)" "unprognostic (9.94e-3)" "unprognostic (2.87e-2)" "unprognostic (1.86e-1)" "unprognostic (8.22e-2)" "unprognostic (4.42e-1)" "potential prognostic favorable (4.44e-4)" "unprognostic (4.46e-2)" "unprognostic (8.20e-2)" "unprognostic (1.44e-1)" "unprognostic (1.37e-1)" "unprognostic (5.29e-2)" "unprognostic (5.16e-2)" "unprognostic (9.90e-3)" "unprognostic (1.20e-2)" "unprognostic (1.93e-1)" "unprognostic (7.61e-3)" "potential prognostic favorable (7.70e-4)" LRRC34 MGC27085 ENSG00000171757 "Leucine rich repeat containing 34" Q8IZ02 3 169793003-169812986 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 11.9" "Cell type enhanced" "Detected in many" "Early spermatids: 106.4;Ependymal cells: 79.0;Epididymal efferent duct ciliated cells: 72.2;Fallopian tube ciliated cells: 93.8;Late primary spermatocytes: 264.6;Respiratory ciliated cells: 134.4" "Group enriched" "Detected in many" 5 "Ciliated cells: 134.4;Spermatogenic cell types: 264.6" "Cell type enhanced" "Detected in all" "ependymal cell: 92.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 13551 "Fallopian tube cells: 1355082.5" "Tissue enriched" "Detected in single" 6188 "fallopian tube: 618792.4" HPA035747 Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "HPA035747: " "unprognostic (1.85e-1)" "unprognostic (4.25e-3)" "validated prognostic unfavorable (8.00e-4)" "validated prognostic unfavorable (1.63e-5)" "unprognostic (1.12e-1)" "unprognostic (4.35e-1)" "unprognostic (8.69e-2)" "unprognostic (1.64e-2)" "unprognostic (3.09e-2)" "unprognostic (6.54e-3)" "unprognostic (1.23e-1)" "unprognostic (1.18e-1)" LRRC46 MGC16309 ENSG00000141294 "Leucine rich repeat containing 46" Q96FV0 17 47831634-47837719 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 73.8;testis: 49.1" "Cell type enhanced" "Detected in some" "Early spermatids: 126.8;Endometrial ciliated cells: 171.1;Ependymal cells: 87.6;Epididymal efferent duct ciliated cells: 183.8;Fallopian tube ciliated cells: 392.7;Late primary spermatocytes: 305.5;Late spermatids: 85.5;Respiratory ciliated cells: 318.3" "Group enriched" "Detected in many" 42 "Ciliated cells: 392.7;Spermatogenic cell types: 305.5" "Cell type enriched" "Detected in some" 9 "ependymal cell: 107.0" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 14.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in single" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 175092 "Fallopian tube cells: 17509213.9" "Tissue enriched" "Detected in single" 111361 "fallopian tube: 11136092.1" HPA074893 Enhanced Approved "Nuclear bodies,Plasma membrane,Primary cilium,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "Plasma membrane" "Nuclear bodies, Primary cilium, Basal body" "HPA074893: " "unprognostic (1.91e-1)" "unprognostic (2.45e-1)" "potential prognostic favorable (5.86e-4)" "unprognostic (5.47e-3)" "unprognostic (6.66e-2)" "unprognostic (1.16e-2)" "unprognostic (1.44e-1)" "unprognostic (4.80e-2)" "unprognostic (2.06e-1)" "unprognostic (1.93e-1)" "unprognostic (2.58e-1)" "unprognostic (9.39e-2)" "unprognostic (1.61e-2)" "unprognostic (3.74e-1)" "unprognostic (3.09e-1)" "unprognostic (1.53e-1)" LRRC75A "C17orf76, FAM211A, FLJ35696" ENSG00000181350 "Leucine rich repeat containing 75A" Q8NAA5 17 16441577-16492193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7473 "Astrocytes and Neuropil: 492700.2;Microglia and Neuropil: 794497.5;Neurons: 954710.3" "Group enriched" "Detected in some" 5655 "cerebral cortex: 821408.5;lymphoid tissue: 309572.1" "HPA028528, HPA065840" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 51: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 17: Non-specific - RNA processing" Nucleoplasm "Nucleoli, Cytosol" "HPA028528: , HPA065840: " "unprognostic (7.69e-3)" "unprognostic (5.11e-3)" "unprognostic (1.42e-1)" "unprognostic (1.57e-1)" "unprognostic (1.16e-1)" "unprognostic (9.48e-2)" "unprognostic (3.21e-2)" "unprognostic (2.68e-2)" "unprognostic (1.51e-1)" "unprognostic (5.56e-3)" "unprognostic (3.44e-2)" "unprognostic (2.17e-1)" "unprognostic (7.15e-3)" "unprognostic (2.53e-2)" "unprognostic (5.81e-2)" "unprognostic (4.01e-3)" "unprognostic (1.56e-1)" "unprognostic (6.61e-2)" "unprognostic (1.02e-2)" "unprognostic (8.46e-2)" "unprognostic (2.97e-1)" "potential prognostic favorable (6.09e-4)" "unprognostic (3.85e-1)" "unprognostic (6.06e-3)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (4.97e-4)" LRRC8C AD158 ENSG00000171488 "Leucine rich repeat containing 8 VRAC subunit C" Q8TDW0 1 89633072-89769903 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Early spermatids: 4.9;Late spermatids: 9.5" "Cell type enriched" "Detected in single" 9 "Spermatogenic cell types: 9.5" "Cell type enhanced" "Detected in single" "endothelial cell: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 9.0;monocytes: 6.6;T-cells: 11.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 5990712.7" "Group enriched" "Detected in many" "fallopian tube: 6141524.4;lymphoid tissue: 2120656.4;ovary: 4377631.4" HPA029347 Uncertain Uncertain "Golgi apparatus" No No "Cluster 33: Non-specific - ATP binding" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 "Golgi apparatus" "HPA029347: " "unprognostic (2.74e-1)" "unprognostic (3.24e-2)" "unprognostic (3.50e-3)" "unprognostic (6.20e-2)" "unprognostic (8.73e-2)" "unprognostic (9.78e-2)" "unprognostic (6.92e-2)" "unprognostic (3.22e-2)" "unprognostic (4.23e-3)" "unprognostic (5.68e-2)" "potential prognostic favorable (1.09e-6)" "unprognostic (2.13e-3)" "unprognostic (2.85e-2)" "unprognostic (3.30e-2)" "unprognostic (1.22e-1)" "unprognostic (2.14e-2)" "unprognostic (3.02e-2)" "unprognostic (2.03e-2)" "unprognostic (5.12e-1)" "unprognostic (1.77e-2)" "unprognostic (2.48e-1)" "unprognostic (1.71e-1)" "unprognostic (2.27e-3)" "unprognostic (2.13e-1)" "unprognostic (3.98e-1)" "unprognostic (6.66e-2)" "unprognostic (2.20e-1)" "unprognostic (1.80e-2)" "unprognostic (8.81e-2)" "unprognostic (7.47e-3)" "unprognostic (2.57e-2)" LRRCC1 "CLERC, KIAA1764, VFL1" ENSG00000133739 "Leucine rich repeat and coiled-coil centrosomal protein 1" Q9C099 8 85107215-85146080 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 31.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 109.5;Early spermatids: 154.9;Erythrocyte progenitors: 96.4;Late primary spermatocytes: 389.0;Late spermatids: 246.7" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 389.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 895 "Fallopian tube cells: 89542.2" "Not detected" "Not detected" "HPA012893, HPA075880" Uncertain Supported "Vesicles,Primary cilium,Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 "Centrosome, Basal body" "Vesicles, Primary cilium, Primary cilium tip, Cytosol" "HPA012893: , HPA075880: " "unprognostic (2.40e-2)" "unprognostic (1.03e-2)" "unprognostic (3.62e-1)" "unprognostic (5.44e-2)" "unprognostic (7.05e-2)" "unprognostic (7.71e-3)" "unprognostic (3.35e-1)" "unprognostic (9.94e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (1.15e-3)" "unprognostic (4.81e-2)" "unprognostic (6.77e-2)" "unprognostic (8.28e-3)" "unprognostic (1.56e-2)" "unprognostic (6.74e-2)" "unprognostic (5.44e-2)" "unprognostic (5.14e-2)" "unprognostic (1.11e-1)" "unprognostic (1.87e-1)" "unprognostic (2.49e-2)" "unprognostic (1.18e-1)" "unprognostic (2.05e-1)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (9.77e-2)" "unprognostic (8.32e-2)" "unprognostic (8.33e-2)" "unprognostic (1.70e-1)" "unprognostic (2.06e-2)" "unprognostic (6.31e-2)" LRRN4 "C20orf75, dJ1056H1.1, NLRR4" ENSG00000125872 "Leucine rich repeat neuronal 4" Q8WUT4 20 6040546-6054060 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.8;lung: 9.8" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Alveolar cells type 1: 49.7;Cardiomyocytes: 29.9;Epicardial cells: 70.5;Mesothelial cells: 25.7;Oocytes: 13.8" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Alveolar cells: 49.7;Barrier epithelial cells: 70.5;Myocytes: 29.9" "Cell type enhanced" "Detected in some" "medium spiny neuron: 1.9" "Group enriched" "Detected in some" 6 "Kidney Renal Papillary Cell Carcinoma (TCGA): 45.6;Lung Adenocarcinoma (TCGA): 12.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 49.3" "Adipose visceral - Mesothelial cells, Pancreas - Ductal cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enhanced" "Detected in some" "blood vessel: 60191.7;lung: 123152.9" HPA075974 Uncertain "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 21000 "Cluster 13: Lung - Secretion" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 5 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA075974: " "unprognostic (1.18e-1)" "unprognostic (1.04e-1)" "unprognostic (2.84e-1)" "potential prognostic favorable (7.86e-4)" "unprognostic (5.82e-2)" "unprognostic (1.86e-1)" "unprognostic (2.08e-1)" "unprognostic (6.48e-3)" "unprognostic (8.88e-2)" "unprognostic (4.53e-2)" LRSAM1 "CMT2P, FLJ31641, RIFLE, TAL" ENSG00000148356 "Leucine rich repeat and sterile alpha motif containing 1" Q6UWE0 9 127451489-127503499 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia and Neuropil: 11450172.4" "Tissue enhanced" "Detected in many" "cerebral cortex: 27658282.0" "HPA021403, HPA021844, CAB037304" Supported Approved Cytosol NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 16 Cytosol "CAB037304: , HPA021403: , HPA021844: " "unprognostic (8.84e-3)" "unprognostic (3.66e-2)" "unprognostic (2.66e-1)" "unprognostic (2.08e-2)" "unprognostic (6.10e-2)" "unprognostic (1.53e-2)" "unprognostic (3.00e-2)" "potential prognostic favorable (3.52e-4)" "unprognostic (5.78e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (5.13e-8)" "unprognostic (3.78e-2)" "unprognostic (8.32e-3)" "unprognostic (2.05e-1)" "unprognostic (7.42e-2)" "unprognostic (2.77e-1)" "unprognostic (2.52e-1)" "unprognostic (5.01e-2)" "unprognostic (4.86e-2)" "unprognostic (2.51e-2)" "unprognostic (1.93e-2)" "unprognostic (9.39e-3)" "unprognostic (3.26e-2)" "unprognostic (5.51e-2)" "unprognostic (1.76e-1)" "unprognostic (8.52e-2)" "unprognostic (1.37e-2)" "unprognostic (3.26e-1)" "unprognostic (5.66e-1)" "unprognostic (2.99e-1)" "unprognostic (1.45e-1)" LSG1 FLJ11301 ENSG00000041802 "Large 60S subunit nuclear export GTPase 1" Q9H089 3 194640791-194672463 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "pancreas: 8676482.9" "HPA037704, HPA037705" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 63: Non-specific - Protein processing" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 30 "Nuclear bodies, Cytosol" Nucleoplasm "HPA037704: , HPA037705: " "unprognostic (2.79e-1)" "potential prognostic unfavorable (8.25e-4)" "unprognostic (1.27e-1)" "unprognostic (2.20e-1)" "unprognostic (1.76e-1)" "unprognostic (3.75e-1)" "unprognostic (4.18e-2)" "unprognostic (5.41e-3)" "unprognostic (9.76e-2)" "unprognostic (2.02e-3)" "unprognostic (1.92e-3)" "unprognostic (1.33e-1)" "unprognostic (9.20e-2)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (1.38e-1)" "unprognostic (2.66e-3)" "unprognostic (2.71e-2)" "unprognostic (6.65e-2)" "unprognostic (5.04e-2)" "unprognostic (3.55e-1)" "unprognostic (6.99e-2)" "unprognostic (1.53e-2)" "unprognostic (5.56e-2)" "unprognostic (9.18e-3)" "unprognostic (6.44e-3)" "unprognostic (1.49e-1)" "unprognostic (8.84e-2)" "unprognostic (6.01e-2)" "unprognostic (2.24e-1)" "unprognostic (4.29e-2)" "unprognostic (2.78e-2)" LUZP1 LUZP ENSG00000169641 "Leucine zipper protein 1" Q86V48 1 23084030-23177808 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 366.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 39.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Lung - Endothelial cells, Spleen - Endothelial cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "fallopian tube: 8744867.4" "HPA028506, HPA028542, HPA028552" Enhanced Approved "Vesicles,Plasma membrane,Actin filaments,Cytokinetic bridge,Centrosome,Cytosol" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 24 "Actin filaments" "Vesicles, Plasma membrane, Cytokinetic bridge, Centrosome, Cytosol" "HPA028506: , HPA028542: , HPA028552: " "unprognostic (1.41e-1)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (3.36e-3)" "unprognostic (1.64e-2)" "unprognostic (7.75e-2)" "unprognostic (8.16e-2)" "unprognostic (1.55e-1)" "unprognostic (2.68e-1)" "unprognostic (1.86e-3)" "validated prognostic favorable (3.92e-7)" "validated prognostic favorable (5.65e-5)" "potential prognostic favorable (2.56e-4)" "unprognostic (5.01e-3)" "unprognostic (1.43e-1)" "unprognostic (2.70e-2)" "unprognostic (1.32e-3)" "unprognostic (9.91e-3)" "unprognostic (2.38e-1)" "unprognostic (9.69e-3)" "unprognostic (1.03e-3)" "unprognostic (5.40e-2)" "unprognostic (1.48e-1)" "unprognostic (2.64e-1)" "unprognostic (3.42e-2)" "unprognostic (5.53e-3)" "unprognostic (5.46e-2)" "unprognostic (2.78e-1)" "unprognostic (5.06e-1)" "unprognostic (1.98e-1)" "unprognostic (2.10e-1)" LXN ENSG00000079257 Latexin Q9BS40 3 158645822-158672648 "Predicted intracellular proteins" "Inflammatory response" "Heparin-binding, Metalloenzyme inhibitor, Metalloprotease inhibitor, Protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 135.9;Erythrocyte progenitors: 120.1;Fallopian tube ciliated cells: 196.4;Mast cells: 130.4;Mesothelial cells: 202.6;Platelets: 131.4;Prostatic club cells: 249.5;Respiratory ciliated cells: 136.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 202.6;Ciliated cells: 196.4;Glandular cells: 249.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Lung - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA014179, CAB025128" Enhanced Approved Nucleoplasm,Cytosol No NA 880000 "Cluster 35: Neutrophils - Protein binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 21 "Nucleoplasm, Cytosol" "CAB025128: , HPA014179: " "unprognostic (3.74e-3)" "unprognostic (1.26e-1)" "unprognostic (6.87e-2)" "unprognostic (6.08e-2)" "unprognostic (9.34e-2)" "unprognostic (9.36e-2)" "unprognostic (6.92e-2)" "unprognostic (2.86e-2)" "unprognostic (5.91e-2)" "unprognostic (6.54e-2)" "validated prognostic favorable (9.11e-4)" "validated prognostic favorable (3.37e-5)" "unprognostic (1.03e-2)" "unprognostic (6.72e-2)" "unprognostic (2.06e-1)" "unprognostic (5.02e-2)" "unprognostic (2.96e-2)" "unprognostic (2.19e-2)" "unprognostic (2.22e-1)" "unprognostic (5.98e-2)" "unprognostic (2.03e-2)" "unprognostic (9.32e-2)" "unprognostic (6.32e-2)" "unprognostic (4.94e-2)" "unprognostic (4.15e-2)" "unprognostic (2.64e-2)" "unprognostic (5.66e-3)" "unprognostic (3.91e-2)" "unprognostic (6.92e-2)" "unprognostic (1.74e-1)" "unprognostic (1.58e-1)" LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.9;intestine: 11.2;lymphoid tissue: 29.2" "Cell type enhanced" "Detected in some" "B-cells: 425.1;cDC: 47.6;Innate lymphoid cells: 28.3;NK-cells: 53.0;pDCs: 102.5;Plasma cells: 124.2;T-cells: 73.5" "Cell type enhanced" "Detected in many" "B-cells: 425.1;dendritic cells: 102.5;Plasma cells: 124.2;T-cells: 73.5" "Cell type enriched" "Detected in single" 149 "leukocyte: 105.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 113.2;MAIT T-cell: 113.7;memory B-cell: 56.2;memory CD4 T-cell: 97.8;memory CD8 T-cell: 109.8;naive B-cell: 53.0;naive CD4 T-cell: 110.0;naive CD8 T-cell: 112.6;plasmacytoid DC: 73.0;T-reg: 80.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 15.9;Myeloma: 38.0" "Adipose visceral - T-cells, Adrenal gland - T-cells, Colon - T-cells, Heart muscle - T-cells, Liver - T-cells, Minor Salivary Gland - Plasma cells, Pancreas - T-cells, Prostate - T-cells, Skin - T-cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "T-cells: 404826.8" "Tissue enriched" "Detected in single" 1544 "lymphoid tissue: 154396.0" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" "Secreted - unknown location" Immunity NA NA 25000 "Cluster 11: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Plasma membrane" "Centriolar satellite" "HPA050917: " "unprognostic (8.79e-2)" "unprognostic (2.67e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (4.94e-4)" "unprognostic (5.62e-2)" "unprognostic (2.44e-1)" "potential prognostic favorable (1.37e-4)" "unprognostic (1.07e-1)" "unprognostic (8.10e-2)" "unprognostic (2.28e-1)" "unprognostic (3.03e-3)" "potential prognostic favorable (1.86e-4)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (5.74e-2)" "unprognostic (2.82e-1)" "unprognostic (5.85e-2)" "unprognostic (2.86e-1)" "unprognostic (1.11e-3)" "potential prognostic favorable (3.48e-4)" "unprognostic (4.69e-2)" "unprognostic (5.81e-2)" "unprognostic (2.47e-2)" LYPD5 FLJ30469 ENSG00000159871 "LY6/PLAUR domain containing 5" Q6UWN5 19 43785874-43827206 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skin 1: 48.2" "Cell type enhanced" "Detected in many" "Early spermatids: 36.9;Esophageal apical cells: 130.1;Late primary spermatocytes: 52.0;Late spermatids: 158.5;Syncytiotrophoblasts: 35.6" "Group enriched" "Detected in many" 4 "Apical squamous epithelial cells: 130.1;Spermatogenic cell types: 158.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 25.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 10.5" "Colon - Enteric glia cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Urothelial cells, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042511, HPA054670" Approved Approved Nucleoplasm,Cytosol No NA "Cluster 40: Monocytes - Innate immune response" "Cluster 37: Skin - Keratinization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 8 "Nucleoplasm, Cytosol" "HPA042511: , HPA054670: " "potential prognostic favorable (7.20e-6)" "unprognostic (7.03e-2)" "unprognostic (1.26e-1)" "unprognostic (4.65e-2)" "unprognostic (1.58e-1)" "unprognostic (6.38e-2)" "unprognostic (4.49e-2)" "unprognostic (2.24e-1)" "unprognostic (1.88e-2)" "potential prognostic favorable (1.83e-5)" "unprognostic (3.04e-2)" "unprognostic (4.80e-3)" "unprognostic (1.33e-2)" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (2.70e-1)" "unprognostic (8.25e-2)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (7.15e-2)" "unprognostic (3.47e-1)" "unprognostic (1.14e-1)" "unprognostic (1.18e-2)" "unprognostic (5.96e-2)" "unprognostic (2.20e-1)" "unprognostic (1.92e-1)" "unprognostic (2.37e-1)" LYPLA1 "APT-1, LPL1" ENSG00000120992 "Lysophospholipase 1" O75608 8 54046367-54102017 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 974.8;Esophageal apical cells: 886.5;Extravillous trophoblasts: 482.5;Late spermatids: 1093.6;Syncytiotrophoblasts: 543.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 886.5;Spermatogenic cell types: 1093.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA050941, HPA063151" Enhanced Approved Nucleoplasm,Cytosol NA NA 280000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 2 "Nucleoplasm, Cytosol" "HPA050941: , HPA063151: " "unprognostic (3.76e-2)" "unprognostic (5.67e-2)" "unprognostic (3.81e-2)" "unprognostic (4.99e-2)" "unprognostic (5.31e-2)" "unprognostic (2.16e-1)" "unprognostic (3.95e-1)" "unprognostic (8.13e-2)" "unprognostic (7.96e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (9.38e-4)" "unprognostic (4.46e-2)" "unprognostic (4.91e-2)" "unprognostic (3.83e-2)" "unprognostic (5.23e-2)" "unprognostic (4.49e-3)" "unprognostic (1.49e-1)" "unprognostic (4.08e-2)" "unprognostic (1.04e-2)" "unprognostic (9.71e-2)" "unprognostic (7.54e-3)" "validated prognostic unfavorable (5.24e-4)" "validated prognostic unfavorable (9.32e-4)" "unprognostic (1.56e-1)" "unprognostic (2.62e-2)" "unprognostic (3.63e-1)" "unprognostic (5.54e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "unprognostic (1.30e-1)" LYPLA2 APT-2 ENSG00000011009 "Lysophospholipase 2" O95372 1 23791145-23795539 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 78.0;Epididymal efferent duct ciliated cells: 100.3;Esophageal apical cells: 94.3;Extravillous trophoblasts: 77.7;Megakaryocytes: 74.2;Migrating cytotrophoblasts: 79.8;Syncytiotrophoblasts: 77.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" HPA063151 Approved Nucleoplasm,Cytosol NA NA 59000 "Cluster 29: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 3 "Nucleoplasm, Cytosol" "HPA063151: " "unprognostic (4.79e-2)" "unprognostic (5.40e-2)" "unprognostic (3.79e-1)" "unprognostic (2.81e-2)" "unprognostic (5.82e-2)" "unprognostic (2.28e-1)" "unprognostic (1.75e-2)" "unprognostic (1.18e-2)" "unprognostic (2.14e-2)" "unprognostic (2.15e-2)" "unprognostic (1.97e-2)" "unprognostic (5.75e-2)" "unprognostic (1.59e-3)" "potential prognostic unfavorable (6.08e-8)" "unprognostic (1.20e-3)" "unprognostic (1.52e-1)" "unprognostic (7.48e-2)" "unprognostic (1.52e-1)" "unprognostic (1.09e-1)" "unprognostic (1.52e-1)" "unprognostic (4.51e-2)" "unprognostic (4.63e-2)" "unprognostic (1.03e-1)" "unprognostic (1.02e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (5.49e-2)" "unprognostic (7.45e-2)" "unprognostic (3.15e-1)" "unprognostic (1.05e-2)" "unprognostic (6.51e-2)" LYRM1 A211C6.1 ENSG00000102897 "LYR motif containing 1" O43325 16 20899868-20925006 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 204.2;Late primary spermatocytes: 198.8;Late spermatids: 779.3" "Cell type enriched" "Detected in all" 6 "Spermatogenic cell types: 779.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 155.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 155.4" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Microglia and Neuropil: 7090996.5" "Group enriched" "Detected in some" "cerebral cortex: 2525166.4;fallopian tube: 873473.6;heart muscle: 3216439.2;liver: 1790851.2" HPA059840 Supported Nucleoplasm,Midbody Yes No "Cluster 32: Basophils - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Nucleoplasm Midbody "HPA059840: " "unprognostic (2.25e-2)" "unprognostic (1.77e-1)" "unprognostic (7.15e-2)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (1.76e-1)" "unprognostic (3.12e-1)" "unprognostic (5.20e-1)" "unprognostic (3.45e-1)" "unprognostic (3.17e-2)" "unprognostic (1.20e-1)" "unprognostic (2.32e-2)" "unprognostic (8.26e-2)" "unprognostic (2.47e-1)" "unprognostic (8.59e-2)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (8.21e-2)" "unprognostic (9.38e-2)" "unprognostic (1.50e-1)" "unprognostic (2.90e-2)" "unprognostic (2.49e-2)" "unprognostic (1.58e-1)" "unprognostic (1.09e-1)" "unprognostic (4.11e-1)" "unprognostic (1.90e-1)" "unprognostic (7.06e-2)" "unprognostic (4.90e-2)" "unprognostic (4.09e-2)" "unprognostic (2.42e-1)" "potential prognostic favorable (6.58e-5)" LYSMD4 FLJ33008 ENSG00000183060 "LysM domain containing 4" Q5XG99 15 99715697-99733561 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 72.4;Epicardial cells: 40.9" "Cell type enhanced" "Detected in all" "Myocytes: 72.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029152, HPA059824" Approved Approved "Actin filaments,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" Cytosol "Actin filaments" "HPA029152: , HPA059824: " "unprognostic (4.93e-2)" "unprognostic (1.67e-1)" "unprognostic (3.50e-2)" "unprognostic (2.83e-1)" "unprognostic (7.08e-2)" "unprognostic (1.84e-1)" "unprognostic (5.19e-3)" "unprognostic (9.55e-2)" "unprognostic (1.08e-1)" "unprognostic (7.46e-2)" "unprognostic (3.93e-2)" "unprognostic (4.61e-3)" "unprognostic (2.38e-2)" "unprognostic (6.50e-3)" "unprognostic (3.08e-2)" "unprognostic (1.05e-1)" "unprognostic (3.16e-1)" "unprognostic (2.42e-1)" "unprognostic (1.19e-2)" "unprognostic (2.37e-1)" "unprognostic (1.71e-2)" "unprognostic (7.80e-2)" "unprognostic (1.92e-1)" "unprognostic (3.72e-1)" "unprognostic (1.27e-2)" "unprognostic (1.58e-1)" "unprognostic (1.54e-1)" "unprognostic (1.12e-1)" "unprognostic (3.34e-1)" "unprognostic (1.45e-1)" "unprognostic (3.86e-1)" LYST "CHS, CHS1, Mauve" ENSG00000143669 "Lysosomal trafficking regulator" Q99698 1 235661041-235883724 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 97.8" "Cell type enhanced" "Detected in all" "Melanocytes: 779.3;Monocyte progenitors: 1213.5;Neutrophil progenitors: 1647.3;Neutrophils: 1674.5;Rod photoreceptor cells: 597.4" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 1213.5;Neutrophils: 1674.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 14.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 156.2" "Group enriched" "Detected in all" 9 "granulocytes: 156.2;monocytes: 52.4" "Cancer enhanced" "Detected in all" "skin cancer: 53.4" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Keratinocytes: 5945356.7;Neutrophils: 16403376.6" "Tissue enriched" "Detected in many" "bone marrow: 29920608.3" "HPA053366, HPA055725" Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 5: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA053366: , HPA055725: " "unprognostic (5.36e-2)" "unprognostic (1.45e-1)" "unprognostic (6.68e-2)" "unprognostic (1.02e-1)" "unprognostic (7.98e-2)" "unprognostic (8.80e-2)" "unprognostic (1.12e-1)" "unprognostic (4.95e-2)" "unprognostic (1.37e-1)" "unprognostic (6.01e-2)" "potential prognostic favorable (3.52e-4)" "unprognostic (3.10e-2)" "unprognostic (9.39e-2)" "unprognostic (6.25e-3)" "unprognostic (2.68e-3)" "unprognostic (3.24e-2)" "unprognostic (4.96e-2)" "unprognostic (9.41e-2)" "unprognostic (1.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.22e-1)" "unprognostic (7.10e-2)" "unprognostic (1.31e-1)" "unprognostic (3.54e-1)" "unprognostic (3.55e-2)" "unprognostic (1.42e-1)" "unprognostic (1.82e-1)" "unprognostic (1.38e-1)" "unprognostic (5.41e-2)" "unprognostic (5.39e-2)" LZIC MGC15436 ENSG00000162441 "Leucine zipper and CTNNBIP1 domain containing" Q8WZA0 1 9922113-9943407 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 176.9;Early spermatids: 285.6;Late primary spermatocytes: 345.7;Megakaryocytes: 204.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 345.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA028184, HPA058614" Approved Approved Nucleoplasm,Cytosol NA NA 310000 "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 5 Nucleoplasm Cytosol "HPA028184: , HPA058614: " "unprognostic (1.90e-1)" "unprognostic (2.02e-2)" "unprognostic (2.60e-1)" "unprognostic (8.05e-2)" "unprognostic (5.22e-2)" "unprognostic (1.68e-1)" "unprognostic (1.16e-1)" "unprognostic (3.76e-1)" "unprognostic (6.58e-2)" "unprognostic (6.32e-3)" "potential prognostic favorable (1.72e-6)" "unprognostic (1.32e-3)" "unprognostic (2.89e-1)" "validated prognostic unfavorable (2.08e-4)" "validated prognostic unfavorable (3.53e-4)" "unprognostic (2.22e-1)" "unprognostic (2.23e-1)" "unprognostic (2.73e-2)" "unprognostic (2.65e-1)" "unprognostic (4.29e-1)" "unprognostic (9.68e-3)" "unprognostic (1.65e-3)" "unprognostic (1.93e-1)" "unprognostic (2.46e-1)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (9.33e-2)" "unprognostic (6.19e-2)" "unprognostic (7.83e-2)" "unprognostic (2.31e-2)" LZTFL1 BBS17 ENSG00000163818 "Leucine zipper transcription factor like 1" Q9NQ48 3 45823316-45916042 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 97.8;Fallopian tube ciliated cells: 106.1;Late primary spermatocytes: 355.8;Respiratory ciliated cells: 121.2;Thymocytes: 141.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 355.8;T-cells: 141.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 25387310.5" "Low tissue specificity" "Detected in many" "HPA043466, HPA048447" Enhanced Supported "Primary cilium,Primary cilium transition zone,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 31 Cytosol "Primary cilium, Primary cilium transition zone" "HPA043466: , HPA048447: " "unprognostic (1.91e-2)" "unprognostic (1.41e-2)" "unprognostic (4.77e-2)" "unprognostic (7.97e-2)" "unprognostic (1.99e-1)" "unprognostic (2.56e-1)" "unprognostic (2.51e-1)" "unprognostic (1.54e-2)" "unprognostic (8.04e-2)" "unprognostic (1.02e-2)" "potential prognostic favorable (2.20e-6)" "unprognostic (1.15e-2)" "unprognostic (1.38e-1)" "unprognostic (1.56e-2)" "unprognostic (2.83e-1)" "unprognostic (2.09e-2)" "unprognostic (8.90e-2)" "unprognostic (8.08e-2)" "unprognostic (4.35e-2)" "unprognostic (1.85e-1)" "unprognostic (2.35e-3)" "unprognostic (1.16e-1)" "unprognostic (1.24e-1)" "unprognostic (1.94e-1)" "unprognostic (6.88e-3)" "unprognostic (5.19e-2)" "unprognostic (2.89e-1)" "unprognostic (2.81e-2)" "unprognostic (8.32e-2)" "unprognostic (6.37e-2)" "unprognostic (2.02e-2)" LZTR1 "BTBD29, LZTR-1" ENSG00000099949 "Leucine zipper like transcription regulator 1" Q8N653 22 20982269-20999032 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 23.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Oocytes: 11220383.2" "Tissue enhanced" "Detected in some" "lymphoid tissue: 11717.8" "HPA067852, HPA068772, HPA071248" Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 102: Non-specific - Mixed function" 15 Nucleoplasm "Centrosome, Cytosol" "HPA067852: , HPA068772: , HPA071248: " "unprognostic (6.18e-2)" "unprognostic (1.65e-1)" "unprognostic (2.94e-3)" "unprognostic (3.34e-2)" "unprognostic (3.53e-2)" "unprognostic (3.49e-1)" "unprognostic (1.09e-1)" "unprognostic (2.56e-2)" "unprognostic (2.17e-1)" "unprognostic (4.18e-3)" "potential prognostic favorable (1.12e-4)" "unprognostic (6.63e-2)" "unprognostic (2.25e-2)" "unprognostic (1.08e-2)" "unprognostic (3.76e-1)" "unprognostic (9.92e-2)" "unprognostic (5.38e-2)" "unprognostic (1.35e-1)" "unprognostic (1.86e-1)" "unprognostic (6.36e-2)" "unprognostic (1.56e-2)" "unprognostic (2.23e-1)" "unprognostic (1.48e-3)" "unprognostic (3.62e-2)" "unprognostic (3.99e-2)" "unprognostic (1.45e-2)" "unprognostic (6.22e-3)" "unprognostic (4.88e-2)" "unprognostic (8.92e-2)" "unprognostic (8.65e-3)" "unprognostic (2.56e-1)" LZTS2 "KIAA1813, LAPSER1" ENSG00000107816 "Leucine zipper tumor suppressor 2" Q9BRK4 10 100996618-101007836 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 63.3;Tuft cells: 69.2" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "oligodendrocyte: 83.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Glomeruli: 5105372.3" "Tissue enriched" "Detected in some" "lymphoid tissue: 1711677.1" HPA044956 Approved Approved "Plasma membrane,Cytosol" No Yes "Cluster 24: Non-specific - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 62: Smooth muscle cells - Muscle contraction" 256 "Plasma membrane, Cytosol" "HPA044956: " "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (1.95e-2)" "unprognostic (3.52e-2)" "unprognostic (2.53e-3)" "unprognostic (2.61e-1)" "unprognostic (5.63e-2)" "potential prognostic favorable (7.04e-4)" "unprognostic (2.12e-1)" "unprognostic (3.41e-1)" "unprognostic (4.77e-2)" "unprognostic (1.19e-1)" "unprognostic (1.86e-2)" "unprognostic (6.44e-3)" "unprognostic (1.57e-1)" "unprognostic (3.35e-1)" "unprognostic (2.37e-2)" "unprognostic (3.18e-1)" "unprognostic (5.58e-2)" "unprognostic (1.11e-1)" "unprognostic (2.69e-1)" "unprognostic (1.03e-1)" "unprognostic (6.02e-2)" "unprognostic (2.58e-1)" "unprognostic (1.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.85e-1)" "unprognostic (3.30e-1)" "unprognostic (1.18e-1)" "unprognostic (2.91e-1)" "unprognostic (1.33e-1)" MACC1 "7A5, SH3BP4L" ENSG00000183742 "MET transcriptional regulator MACC1" Q6ZN28 7 20134655-20217404 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 11.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 671.7;Endometrial glandular cells: 663.8;Endometrial luminal cells: 741.0;Endometrial secretory cells: 1365.8;Epididymal clear cells: 526.7;Epididymal efferent duct ciliated cells: 428.1;Respiratory deuterosomal cells: 458.2;Respiratory secretory cells: 448.8;Salivary duct cells: 457.0;Urothelial cells: 709.3" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 709.3;Luminal cells: 741.0;Secretory cells: 1365.8" "Cell type enhanced" "Detected in many" "CGE interneuron: 6.7;leukocyte: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Urothelial cells, Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 899247.8;Keratinocytes: 585898.9" "Tissue enriched" "Detected in some" "intestine: 263044.1" "HPA020081, HPA020103, HPA029476, CAB068194" Supported Approved Mitochondria NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" Mitochondria "CAB068194: , HPA020081: , HPA020103: , HPA029476: " "unprognostic (2.65e-1)" "unprognostic (3.77e-2)" "unprognostic (9.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.17e-3)" "unprognostic (1.30e-1)" "unprognostic (2.64e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-2)" "validated prognostic favorable (2.59e-8)" "validated prognostic favorable (2.52e-5)" "potential prognostic favorable (8.02e-8)" "unprognostic (2.18e-1)" "unprognostic (4.90e-2)" "unprognostic (5.12e-2)" "unprognostic (2.28e-1)" "unprognostic (1.01e-1)" "unprognostic (1.10e-2)" "unprognostic (7.15e-3)" "unprognostic (3.71e-3)" "potential prognostic favorable (8.86e-4)" "unprognostic (1.84e-1)" "unprognostic (4.28e-2)" "unprognostic (5.97e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (6.41e-2)" MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA0754, KIAA1251, Lnc-PMIF, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ocular epithelial cells: 2163.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 174552613.5" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments,Basal body" NA NA 3500 "Cluster 3: Non-specific - Nuclear processes" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 100: Stratified epithelial cells - Barrier functions" 19 "Plasma membrane, Actin filaments" "Cell Junctions, Basal body" "HPA013713: , HPA068064: , HPA068103: " "unprognostic (2.46e-2)" "unprognostic (6.12e-2)" "unprognostic (5.98e-2)" "unprognostic (2.65e-1)" "unprognostic (2.75e-1)" "unprognostic (3.92e-1)" "unprognostic (7.24e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (2.04e-1)" "potential prognostic favorable (1.67e-5)" "unprognostic (1.84e-2)" "unprognostic (1.68e-2)" "unprognostic (5.64e-3)" "unprognostic (1.02e-1)" "unprognostic (1.20e-1)" "unprognostic (3.07e-2)" "unprognostic (8.56e-2)" "unprognostic (4.14e-2)" "unprognostic (3.14e-1)" "unprognostic (1.82e-1)" "unprognostic (1.13e-1)" "unprognostic (3.51e-3)" "unprognostic (4.16e-1)" "unprognostic (9.16e-2)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (2.89e-1)" "unprognostic (2.38e-1)" "unprognostic (1.88e-1)" "unprognostic (1.44e-1)" MACROD2 "C20orf133, dJ631M13.5" ENSG00000172264 "Mono-ADP ribosylhydrolase 2" A1Z1Q3 20 13995369-16053197 "Metabolic proteins, Predicted intracellular proteins" "DNA damage" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6002.6;Brain inhibitory neurons: 2370.3;Corticotrophs: 2219.1;Retinal bipolar cells: 3840.5;Thyrotrophs: 2543.9;Transitional alveolar cells: 5447.3" "Cell type enhanced" "Detected in all" "Alveolar cells: 6002.6;Neuronal cells: 3840.5;Pituitary endocrine cells: 2543.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 8.7;naive B-cell: 11.8;neutrophil: 3.6" "Group enriched" "Detected in many" 4 "B-cells: 11.8;granulocytes: 3.6" "Cancer enhanced" "Detected in many" "Kidney cancer: 31.9" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary gland ductal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 6649743.9;Microglia and Neuropil: 6642437.9;Neurons: 6508839.2" "Tissue enriched" "Detected in many" "cerebral cortex: 1910468.5" HPA049076 Enhanced Supported Nucleoplasm,Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nucleoplasm, Nucleoli" "HPA049076: " "unprognostic (8.53e-3)" "unprognostic (4.77e-2)" "unprognostic (1.05e-1)" "unprognostic (5.32e-3)" "unprognostic (3.19e-3)" "unprognostic (3.06e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (3.65e-4)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (4.94e-4)" "unprognostic (3.35e-2)" "unprognostic (3.07e-3)" "unprognostic (2.14e-1)" "unprognostic (2.02e-2)" "unprognostic (1.16e-3)" "unprognostic (1.11e-2)" "unprognostic (6.34e-2)" "unprognostic (4.65e-3)" "unprognostic (2.01e-1)" "unprognostic (1.37e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" "unprognostic (9.55e-2)" "unprognostic (1.67e-1)" "validated prognostic favorable (5.55e-5)" "validated prognostic favorable (7.17e-4)" "unprognostic (1.88e-2)" "unprognostic (5.98e-2)" "unprognostic (1.40e-1)" "unprognostic (4.29e-1)" "unprognostic (4.63e-2)" MACROH2A1 "H2AFY, macroH2A1.2" ENSG00000113648 "MacroH2A.1 histone" O75367 5 135334381-135399914 "Plasma proteins, Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1167.7;Monocyte progenitors: 645.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1167.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA041189, HPA050962" Supported Supported Nucleoplasm NA NA 4700000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 87 Nucleoplasm "HPA041189: , HPA050962: " "unprognostic (2.15e-2)" "unprognostic (9.76e-3)" "unprognostic (1.84e-1)" "unprognostic (5.72e-2)" "unprognostic (8.95e-2)" "unprognostic (3.61e-1)" "unprognostic (5.23e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (2.97e-4)" "potential prognostic favorable (2.15e-4)" "unprognostic (1.29e-2)" "unprognostic (7.43e-2)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (3.94e-2)" "unprognostic (6.03e-2)" "unprognostic (1.51e-1)" "unprognostic (4.59e-2)" "unprognostic (1.20e-1)" "unprognostic (2.73e-1)" "unprognostic (1.75e-1)" "unprognostic (1.86e-1)" "unprognostic (5.69e-2)" "unprognostic (8.85e-2)" "unprognostic (1.57e-2)" "unprognostic (8.82e-2)" "unprognostic (1.35e-1)" "unprognostic (6.26e-2)" "unprognostic (1.59e-1)" "unprognostic (2.64e-1)" MACROH2A2 H2AFY2 ENSG00000099284 "MacroH2A.2 histone" Q9P0M6 10 70052544-70112282 "Predicted intracellular proteins" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 270.1;Granulosa cells: 93.3;Sertoli cells: 111.1" "Cell type enhanced" "Detected in many" "Adipocytes: 270.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "myeloid DC: 12.6" "Group enriched" "Detected in many" 8 "dendritic cells: 12.6;monocytes: 5.4" "Cancer enhanced" "Detected in all" "Neuroblastoma: 116.2" "Kidney - Fibroblasts, Skin - Keratinocyte (other), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 116030881.9" "Low tissue specificity" "Detected in many" "HPA035865, HPA041189" Enhanced Supported Nucleoplasm No No 510000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 89: Adipocytes - Lipid metabolism" 31 Nucleoplasm "HPA035865: , HPA041189: " "potential prognostic favorable (4.96e-4)" "unprognostic (1.54e-1)" "unprognostic (2.32e-1)" "unprognostic (1.67e-1)" "unprognostic (9.58e-2)" "unprognostic (1.37e-2)" "potential prognostic favorable (1.97e-6)" "unprognostic (2.47e-1)" "unprognostic (2.30e-1)" "unprognostic (1.66e-2)" "unprognostic (3.11e-1)" "unprognostic (3.42e-2)" "unprognostic (6.41e-3)" "unprognostic (3.88e-3)" "unprognostic (2.27e-1)" "unprognostic (1.54e-1)" "unprognostic (7.66e-2)" "unprognostic (2.03e-1)" "unprognostic (3.08e-1)" "unprognostic (2.49e-1)" "unprognostic (8.00e-3)" "unprognostic (2.41e-2)" "unprognostic (3.22e-2)" "unprognostic (1.07e-1)" "unprognostic (4.06e-1)" "unprognostic (5.22e-2)" "unprognostic (2.62e-2)" "unprognostic (4.08e-1)" "unprognostic (7.94e-3)" MAEA "EMP, GID9, HLC-10, p44EMLP" ENSG00000090316 "Macrophage erythroblast attacher, E3 ubiquitin ligase" Q7L5Y9 4 1289887-1340147 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Erythrocyte maturation, Ubl conjugation pathway" "Actin-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 282.7" "Cell type enhanced" "Detected in all" "Neutrophils: 282.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in some" "lymphoid tissue: 1384793.9" "HPA036886, HPA058185" Approved Enhanced Nucleoplasm Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 70: Non-specific - Protein processing" "Cluster 1: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 40 Nucleoplasm "HPA036886: , HPA058185: " "unprognostic (1.00e-1)" "unprognostic (8.05e-3)" "unprognostic (1.65e-1)" "unprognostic (1.17e-2)" "unprognostic (6.00e-3)" "unprognostic (5.98e-2)" "unprognostic (9.17e-2)" "unprognostic (1.93e-2)" "unprognostic (3.84e-3)" "unprognostic (2.86e-1)" "potential prognostic favorable (4.00e-6)" "unprognostic (1.67e-2)" "potential prognostic favorable (4.46e-5)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (7.65e-3)" "unprognostic (6.59e-2)" "unprognostic (7.17e-3)" "unprognostic (8.29e-3)" "unprognostic (4.17e-1)" "unprognostic (1.84e-1)" "unprognostic (3.95e-3)" "unprognostic (8.39e-3)" "unprognostic (5.31e-2)" "unprognostic (2.83e-2)" "unprognostic (5.04e-2)" "unprognostic (1.31e-1)" "unprognostic (3.41e-1)" "unprognostic (4.74e-2)" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (6.03e-3)" MAF1 DKFZp586G1123 ENSG00000179632 "MAF1 homolog, negative regulator of RNA polymerase III" Q9H063 8 144104461-144107611 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 210.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 223886.8;Large ducts: 458475.5" "Group enriched" "Detected in some" 292 "bone marrow: 34615.2;lymphoid tissue: 23775.0" "HPA024821, HPA058548, HPA072409" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 34 Nucleoplasm Cytosol "HPA024821: , HPA058548: , HPA072409: " "unprognostic (1.44e-1)" "unprognostic (7.67e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (4.71e-2)" "unprognostic (2.23e-2)" "unprognostic (6.99e-2)" "unprognostic (2.94e-3)" "unprognostic (8.61e-2)" "unprognostic (2.64e-2)" "unprognostic (6.28e-2)" "unprognostic (5.17e-2)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (3.61e-3)" "unprognostic (2.66e-2)" "unprognostic (4.22e-2)" "unprognostic (1.21e-2)" "unprognostic (4.97e-2)" "unprognostic (1.12e-2)" "unprognostic (3.16e-2)" "unprognostic (3.26e-2)" "unprognostic (1.51e-1)" "unprognostic (1.19e-1)" "unprognostic (3.77e-1)" "unprognostic (2.35e-1)" "unprognostic (1.13e-1)" "unprognostic (2.28e-1)" "unprognostic (2.03e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" MAFB KRML ENSG00000204103 "MAF bZIP transcription factor B" Q9Y5Q3 20 40685848-40689236 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 256.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 312.0;Breast myoepithelial cells: 285.0;Hofbauer cells: 568.0;Kupffer cells: 1002.4;Macrophages: 477.8;monocytes: 651.7;Pancreatic islet cells: 192.9" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 1002.4;Secretory cells: 312.0" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 59.7;CGE interneuron: 21.9;LAMP5-LHX6 and Chandelier: 40.1;leukocyte: 23.5;MGE interneuron: 48.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 88.3;non-classical monocyte: 121.9" "Lineage enriched" "Detected in many" 15 "monocytes: 121.9" "Cancer enhanced" "Detected in many" "Bone cancer: 29.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Fibroblasts, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 142 "Hepatocytes: 14235.6" "Not detected" "Not detected" HPA005653 Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Cytosol" Yes NA "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 9 Nucleoplasm "Nucleoli, Golgi apparatus, Cytosol" "HPA005653: " "unprognostic (8.92e-3)" "unprognostic (3.64e-1)" "unprognostic (1.94e-1)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (9.15e-3)" "unprognostic (4.66e-2)" "unprognostic (1.96e-1)" "unprognostic (6.05e-2)" "unprognostic (6.40e-2)" "unprognostic (1.00e-1)" "unprognostic (1.23e-1)" "unprognostic (2.91e-2)" "unprognostic (6.52e-2)" "unprognostic (1.24e-3)" "unprognostic (3.08e-1)" "unprognostic (2.20e-3)" "unprognostic (4.38e-1)" "unprognostic (8.04e-3)" "unprognostic (1.94e-2)" "unprognostic (2.73e-2)" "unprognostic (9.30e-3)" "unprognostic (4.86e-2)" "unprognostic (1.32e-1)" "unprognostic (4.22e-2)" "unprognostic (1.06e-2)" "unprognostic (1.28e-1)" "unprognostic (1.48e-1)" "unprognostic (2.40e-3)" "unprognostic (1.15e-2)" "unprognostic (2.42e-1)" MAFF hMafF ENSG00000185022 "MAF bZIP transcription factor F" Q9ULX9 22 38200767-38216507 "Predicted intracellular proteins, Transcription factors" "Stress response, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 472.2;Endometrial glandular cells: 819.0;Endometrial luminal cells: 687.6;Endometrial secretory cells: 434.0;Epididymal basal cells: 771.6;Esophageal apical cells: 771.1;Syncytiotrophoblasts: 607.3;Urothelial cells: 527.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 771.1;Basal cells: 771.6;Glandular cells: 819.0" "Cell type enhanced" "Detected in many" "endothelial cell: 44.4;vascular associated smooth muscle cell: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 23.9;neutrophil: 8.6;NK-cell: 21.1" "Group enriched" "Detected in many" 6 "granulocytes: 23.9;NK-cells: 21.1" "Cancer enhanced" "Detected in all" "skin cancer: 80.1" "Colon - Neutrophils, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 86 "Keratinocytes: 8641.2" "Tissue enriched" "Detected in many" "ovary: 111713.5" "CAB025341, HPA055371" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 32: Basophils - Transcription" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 18: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 23 Nucleoplasm Mitochondria "CAB025341: , HPA055371: " "unprognostic (1.51e-1)" "unprognostic (3.17e-3)" "unprognostic (3.43e-2)" "unprognostic (4.91e-3)" "unprognostic (2.97e-2)" "unprognostic (2.07e-2)" "unprognostic (2.86e-2)" "unprognostic (3.50e-2)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (3.03e-1)" "unprognostic (4.02e-1)" "unprognostic (2.14e-3)" "unprognostic (2.48e-1)" "unprognostic (1.28e-2)" "unprognostic (9.48e-2)" "unprognostic (4.12e-3)" "unprognostic (2.70e-1)" "unprognostic (4.28e-2)" "unprognostic (1.25e-1)" "unprognostic (8.93e-3)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (6.66e-4)" "unprognostic (1.06e-1)" "unprognostic (3.07e-1)" "unprognostic (3.25e-2)" "unprognostic (1.68e-3)" "unprognostic (3.76e-2)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (8.88e-2)" "unprognostic (1.97e-1)" MAFK "NFE2U, P18" ENSG00000198517 "MAF bZIP transcription factor K" O60675 7 1530702-1543043 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 123.8;Syncytiotrophoblasts: 112.9;Urothelial cells: 78.7" "Cell type enhanced" "Detected in many" "Glandular cells: 123.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Neurons: 102827.2;T-cells: 76141.8" "Not detected" "Not detected" "CAB026820, HPA060841" Enhanced Enhanced Nucleoplasm No No "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 18: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 11 Nucleoplasm "CAB026820: , HPA060841: " "unprognostic (1.40e-1)" "unprognostic (4.14e-2)" "unprognostic (5.87e-2)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (4.46e-2)" "unprognostic (1.62e-1)" "unprognostic (5.84e-3)" "unprognostic (3.60e-3)" "unprognostic (3.58e-2)" "unprognostic (4.84e-3)" "unprognostic (2.63e-2)" "unprognostic (5.49e-2)" "unprognostic (1.01e-1)" "unprognostic (7.82e-2)" "unprognostic (2.44e-2)" "unprognostic (5.45e-3)" "unprognostic (2.18e-1)" "unprognostic (5.46e-2)" "unprognostic (1.48e-1)" "unprognostic (5.26e-2)" "unprognostic (2.27e-1)" "unprognostic (3.49e-1)" "unprognostic (2.35e-3)" "unprognostic (6.65e-2)" "unprognostic (1.21e-1)" "potential prognostic favorable (7.19e-4)" "unprognostic (4.91e-2)" "unprognostic (3.04e-2)" "unprognostic (2.55e-1)" "unprognostic (1.54e-2)" "unprognostic (1.11e-1)" MAG "GMA, S-MAG, SIGLEC-4A, SIGLEC4A" ENSG00000105695 "Myelin associated glycoprotein" P20916 19 35292125-35313807 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 37 "brain: 699.7" "Cell type enriched" "Detected in some" 5 "Oligodendrocytes: 466.0" "Cell type enriched" "Detected in many" 5 "Glial cells: 466.0" "Group enriched" "Detected in many" 34 "committed oligodendrocyte precursor: 230.4;oligodendrocyte: 563.7" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 39.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 12 "plasmacytoid DC: 2.9" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.9" "Cancer enriched" "Detected in single" 8 "skin cancer: 7.6" "Region enhanced" "Detected in all" "white matter: 2743.6" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Astrocytes and Neuropil: 311204892.5" "Tissue enriched" "Detected in some" "cerebral cortex: 190560369.2" "CAB009345, HPA012499" Enhanced Approved "Equatorial segment,Perinuclear theca" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 1 "Equatorial segment, Perinuclear theca" "CAB009345: , HPA012499: " "unprognostic (1.30e-1)" "unprognostic (3.60e-2)" "unprognostic (2.20e-1)" "unprognostic (1.57e-1)" "unprognostic (7.24e-2)" "unprognostic (9.19e-2)" "unprognostic (9.26e-2)" "unprognostic (3.90e-1)" "unprognostic (8.40e-2)" MAGEA9 "CT1.9, MAGE9, MGC8421" ENSG00000123584 "MAGE family member A9" P43362 X 149781930-149787737 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 38 "testis: 3.8" "Cell type enriched" "Detected in single" 4 "Early primary spermatocytes: 2.2" "Cell type enriched" "Detected in single" 22 "Spermatogenic cell types: 2.2" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Esophageal cancer: 3.8;lymphoma: 5.7;Myeloma: 4.1;Sarcoma: 4.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045401, HPA051687" Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 8 "Nucleoplasm, Golgi apparatus" "HPA045401: , HPA051687: " "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "unprognostic (1.68e-1)" "unprognostic (4.10e-1)" "unprognostic (2.65e-1)" "unprognostic (7.22e-3)" MAGEA9B ENSG00000267978 "MAGE family member A9B" P43362 X 149581653-149587459 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 9.5" "Cell type enriched" "Detected in some" 6 "Early primary spermatocytes: 48.3" "Cell type enriched" "Detected in single" 128 "Spermatogenic cell types: 48.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 14.9;Lung Squamous Cell Carcinoma (TCGA): 25.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045401, HPA051687" Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 55: Lymphoma - Immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 5 "Nucleoplasm, Golgi apparatus" "HPA045401: , HPA051687: " "unprognostic (3.27e-2)" "unprognostic (1.81e-1)" "unprognostic (1.97e-2)" "unprognostic (4.58e-1)" "unprognostic (3.15e-1)" "unprognostic (2.20e-2)" "unprognostic (4.84e-2)" "unprognostic (3.34e-2)" "unprognostic (9.55e-2)" "unprognostic (4.45e-2)" "unprognostic (7.11e-3)" "unprognostic (9.64e-3)" MAGEC1 "CT7, CT7.1, MAGE-C1, MGC39366" ENSG00000155495 "MAGE family member C1" O60732 X 141903894-141909374 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 7.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 4.4;Early primary spermatocytes: 22.7;Oocytes: 4.6;Undifferentiated spermatogonia: 12.1" "Cell type enriched" "Detected in some" 4 "Spermatogenic cell types: 22.7" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Skin Cutaneous Melanoma (TCGA): 13.2;Testicular Germ Cell Tumor (TCGA): 5.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 29.3" "Testis - Spermatogonia" "Cell type enriched" "Detected in single" 4756 "Oocytes: 475595.2" "Not detected" "Not detected" "HPA004622, CAB015452" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 4 "Nucleoplasm, Cytosol" "CAB015452: , HPA004622: " "potential prognostic unfavorable (9.12e-4)" "unprognostic (2.97e-3)" "unprognostic (9.27e-2)" "unprognostic (7.32e-2)" "unprognostic (7.42e-2)" "unprognostic (6.52e-2)" "unprognostic (1.17e-1)" "unprognostic (2.47e-1)" "unprognostic (1.03e-1)" "unprognostic (2.17e-3)" "unprognostic (9.33e-2)" MAGEC2 "CT10, HCA587, MAGE-C2, MAGEE1" ENSG00000046774 "MAGE family member C2" Q9UBF1 X 142202342-142205290 "Cancer-related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 184 "testis: 18.4" "Group enriched" "Detected in some" 75 "Differentiating spermatogonia: 61.4;Early primary spermatocytes: 111.4;Undifferentiated spermatogonia: 72.3" "Cell type enriched" "Detected in single" 384 "Spermatogenic cell types: 111.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 33.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 60.2;thyroid cancer: 51.5" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" HPA062230 Enhanced Supported Nucleoplasm,Cytosol Yes NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 19 Nucleoplasm Cytosol "HPA062230: " "unprognostic (4.78e-2)" "unprognostic (2.11e-1)" "unprognostic (5.37e-1)" "unprognostic (7.18e-2)" "unprognostic (6.90e-2)" "unprognostic (3.41e-2)" "unprognostic (7.08e-1)" "unprognostic (3.20e-2)" "unprognostic (5.56e-2)" "unprognostic (4.60e-1)" "unprognostic (1.14e-3)" "unprognostic (3.19e-1)" "unprognostic (2.53e-1)" "unprognostic (4.57e-1)" "unprognostic (8.66e-2)" "unprognostic (6.86e-2)" MAGED2 "11B6, BCG1, HCA10, JCL-1, MAGE-D2, MAGED, MGC8386" ENSG00000102316 "MAGE family member D2" Q9UNF1 X 54807599-54816015 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Tumor antigen" "Bartter syndrome, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 314.7;Granulosa cells: 752.6;Ovarian stromal cells: 337.6;Peritubular myoid cells: 278.5;Platelets: 332.3" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 752.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 403.0" "Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Granulosa cells: 105419062.7" "Low tissue specificity" "Detected in many" "HPA031572, HPA031573" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No 33000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 75: Ovary - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 26 "Nucleoplasm, Nucleoli, Cytosol" "HPA031572: , HPA031573: " "unprognostic (1.07e-1)" "unprognostic (1.49e-1)" "unprognostic (4.62e-2)" "unprognostic (4.92e-1)" "unprognostic (1.84e-1)" "unprognostic (4.51e-2)" "unprognostic (3.78e-3)" "unprognostic (2.10e-2)" "unprognostic (1.33e-1)" "unprognostic (7.88e-2)" "potential prognostic favorable (2.21e-5)" "unprognostic (9.27e-2)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (6.35e-4)" "unprognostic (9.11e-3)" "unprognostic (3.74e-1)" "unprognostic (1.10e-1)" "unprognostic (5.56e-3)" "unprognostic (5.47e-1)" "unprognostic (1.07e-3)" "unprognostic (5.57e-1)" "potential prognostic favorable (6.13e-4)" "unprognostic (1.43e-1)" "unprognostic (2.02e-1)" "unprognostic (2.59e-1)" "unprognostic (9.23e-2)" "unprognostic (2.00e-1)" "unprognostic (2.97e-2)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (4.98e-2)" MAGEE1 "DAMAGE, KIAA1587" ENSG00000198934 "MAGE family member E1" Q9HCI5 X 76427710-76431342 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Tumor antigen" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 25.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 16.1;Brain inhibitory neurons: 15.9;Corticotrophs: 10.4;Other brain neurons: 24.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 31.9;Neuronal cells: 24.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 127785.8;Neurons: 476171.4" "Tissue enriched" "Detected in single" 963 "cerebral cortex: 96334.5" HPA003047 Approved Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 98: Neurons - Neurotransmission & signaling" 22 Cytosol "Cytokinetic bridge" "HPA003047: " "unprognostic (5.33e-2)" "unprognostic (1.43e-2)" "unprognostic (2.34e-1)" "unprognostic (3.80e-2)" "unprognostic (1.03e-1)" "unprognostic (5.33e-3)" "unprognostic (9.46e-2)" "unprognostic (1.57e-2)" "potential prognostic favorable (4.58e-6)" "unprognostic (3.61e-3)" "unprognostic (2.29e-1)" "unprognostic (1.69e-2)" "unprognostic (1.47e-2)" "unprognostic (6.35e-2)" "unprognostic (2.11e-3)" "unprognostic (1.68e-1)" "unprognostic (2.45e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (3.02e-1)" "unprognostic (5.07e-2)" "unprognostic (4.61e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" MAGIX "FLJ21687, JM10, PDZX" ENSG00000269313 "MAGI family member, X-linked" Q9H6Y5 X 49162564-49168774 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 19.0" "Cell type enhanced" "Detected in many" "Breast lactating cells: 128.6;Epididymal efferent duct ciliated cells: 42.4;Fallopian tube ciliated cells: 66.4;Megakaryocytes: 43.3;Respiratory ciliated cells: 50.2;Tuft cells: 57.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 66.4;Secretory cells: 128.6" "Cell type enhanced" "Detected in many" "ependymal cell: 15.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 4.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 768103.6;Hepatocytes: 631396.2" "Tissue enriched" "Detected in some" "Stomach: 1869922.9" "HPA007390, HPA035302" Uncertain Approved "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 70: Non-specific - Protein processing" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 4: Breast lactating luminal cells - Lactation" Nucleoplasm "Mitotic chromosome" "HPA007390: , HPA035302: " "unprognostic (1.05e-3)" "unprognostic (5.35e-2)" "unprognostic (1.65e-1)" "unprognostic (6.86e-2)" "unprognostic (8.11e-3)" "unprognostic (1.92e-1)" "unprognostic (1.19e-3)" "potential prognostic favorable (3.02e-4)" "unprognostic (2.63e-2)" "potential prognostic favorable (1.22e-6)" "unprognostic (3.30e-1)" "potential prognostic favorable (1.32e-5)" "unprognostic (1.90e-1)" "unprognostic (4.43e-2)" "potential prognostic favorable (8.91e-4)" "unprognostic (8.19e-2)" "unprognostic (3.00e-1)" "unprognostic (5.35e-2)" "unprognostic (1.90e-2)" "unprognostic (4.77e-2)" "unprognostic (2.64e-2)" "unprognostic (2.87e-2)" "unprognostic (2.48e-1)" "unprognostic (2.17e-1)" "unprognostic (4.65e-3)" "unprognostic (2.00e-1)" "unprognostic (6.02e-2)" "unprognostic (6.38e-2)" MAL "MVP17, VIP17" ENSG00000172005 "Mal, T cell differentiation protein" P21145 2 95025677-95053992 "Predicted membrane proteins, Transporters" Leukodystrophy "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 687.1;esophagus: 2851.1;vagina: 835.9" "Cell type enriched" "Detected in many" 33 "Esophageal apical cells: 40845.9" "Cell type enriched" "Detected in many" 33 "Apical squamous epithelial cells: 40845.9" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 96.2;oligodendrocyte: 286.7" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 644.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 423.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "memory CD4 T-cell: 218.3;naive CD4 T-cell: 294.2;naive CD8 T-cell: 138.5;T-reg: 234.3" "Lineage enriched" "Detected in many" 38 "T-cells: 294.2" "Cancer enhanced" "Detected in many" "Leukemia: 35.0;ovarian cancer: 68.6;Uterine cancer: 46.9" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Lung - Fibroblasts_1, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA065691 Approved "Golgi apparatus,Centrosome,Basal body" NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 84: Apical squamous epithelium - Cornification" 68 "Golgi apparatus" "Centrosome, Basal body" "HPA065691: " "unprognostic (5.06e-2)" "potential prognostic favorable (5.92e-4)" "unprognostic (3.73e-3)" "unprognostic (3.01e-3)" "unprognostic (2.37e-2)" "unprognostic (3.78e-1)" "unprognostic (2.50e-2)" "unprognostic (3.17e-2)" "unprognostic (7.02e-2)" "unprognostic (1.46e-2)" "unprognostic (6.50e-2)" "unprognostic (4.36e-3)" "potential prognostic favorable (9.54e-4)" "unprognostic (1.86e-2)" "unprognostic (1.92e-2)" "unprognostic (1.43e-1)" "unprognostic (1.94e-1)" "unprognostic (7.50e-2)" "unprognostic (6.90e-2)" "unprognostic (6.08e-2)" "unprognostic (6.32e-2)" "unprognostic (2.31e-1)" "unprognostic (2.91e-1)" "unprognostic (2.98e-2)" "unprognostic (6.92e-2)" "unprognostic (1.82e-2)" MALT1 "MLT, PCASP1" ENSG00000172175 "MALT1 paracaspase" Q9UDY8 18 58671465-58754477 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Ubl conjugation pathway" "Hydrolase, Protease" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 19.0" "Cell type enhanced" "Detected in many" "cDC: 328.8;Innate lymphoid cells: 328.7;monocytes: 322.9;Myonuclei: 283.0;pDCs: 468.6;Prostatic glandular cells: 331.7;Thymocytes: 419.2" "Cell type enhanced" "Detected in all" "dendritic cells: 468.6;T-cells: 419.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in some" "fallopian tube: 5235731.4;lymphoid tissue: 2996860.3" "CAB004494, HPA048432" Enhanced Approved "Nucleoli fibrillar center,Cytosol" No No "Cluster 14: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 15: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 29 "Nucleoli fibrillar center" Cytosol "CAB004494: , HPA048432: " "unprognostic (1.07e-1)" "unprognostic (9.97e-2)" "unprognostic (2.70e-1)" "unprognostic (1.21e-1)" "unprognostic (1.81e-1)" "unprognostic (1.92e-1)" "unprognostic (1.10e-2)" "unprognostic (1.78e-1)" "unprognostic (2.93e-2)" "unprognostic (4.71e-2)" "unprognostic (2.43e-2)" "unprognostic (1.00e-2)" "unprognostic (4.95e-2)" "unprognostic (8.43e-2)" "unprognostic (2.11e-1)" "unprognostic (4.64e-2)" "unprognostic (1.47e-1)" "unprognostic (3.99e-2)" "unprognostic (2.49e-1)" "unprognostic (9.96e-2)" "unprognostic (8.96e-2)" "unprognostic (2.96e-1)" "unprognostic (1.58e-2)" "unprognostic (1.80e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-2)" "unprognostic (3.22e-2)" "unprognostic (1.32e-1)" "unprognostic (2.86e-1)" "unprognostic (2.06e-1)" "unprognostic (5.37e-2)" MAMDC4 "AEGP, DKFZp434M1411, EDTB" ENSG00000177943 "MAM domain containing 4" Q6UXC1 9 136850943-136860799 "Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.6;liver: 31.0" "Cell type enhanced" "Detected in many" "Colonocytes: 24.8;Enterocytes: 20.6;Goblet cells: 25.3;Hepatocytes: 30.1;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "Enterocytes: 24.8;Goblet cells: 25.3;Hepatocytes: 30.1;Secretory gland support: 23.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026377, HPA059977" Approved Nucleoplasm,Cytosol NA Yes "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 65: Non-specific - Cell growth & division" Nucleoplasm Cytosol "CAB026377: , HPA059977: " "unprognostic (2.46e-2)" "unprognostic (7.21e-2)" "unprognostic (1.46e-1)" "unprognostic (1.48e-1)" "unprognostic (2.94e-1)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (1.32e-2)" "unprognostic (1.57e-3)" "unprognostic (6.15e-2)" "unprognostic (8.75e-3)" "unprognostic (1.99e-2)" "unprognostic (8.66e-3)" "unprognostic (7.06e-2)" "unprognostic (2.43e-2)" "unprognostic (1.62e-1)" "unprognostic (1.19e-3)" "potential prognostic favorable (1.78e-5)" "unprognostic (1.95e-1)" "unprognostic (9.33e-3)" "unprognostic (1.05e-1)" "unprognostic (7.41e-3)" "unprognostic (6.76e-3)" "unprognostic (5.25e-1)" "unprognostic (1.17e-1)" "unprognostic (3.10e-1)" MAML2 "KIAA1819, MAM3" ENSG00000184384 "Mastermind like transcriptional coactivator 2" Q8IZL2 11 95976598-96343195 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Notch signaling pathway, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 2700.3" "Cell type enhanced" "Detected in all" "Renal nephron cells: 2700.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 3870.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 335046.9;T-cells: 384428.8" "Tissue enriched" "Detected in single" 1657 "lymphoid tissue: 165662.0" HPA035223 Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" "Nuclear bodies" "Nucleoplasm, Cytosol" "HPA035223: " "unprognostic (7.10e-2)" "unprognostic (4.51e-2)" "unprognostic (4.29e-1)" "unprognostic (4.13e-3)" "unprognostic (1.14e-1)" "unprognostic (1.72e-2)" "unprognostic (9.12e-3)" "unprognostic (1.07e-2)" "unprognostic (1.63e-2)" "unprognostic (9.46e-2)" "validated prognostic favorable (3.01e-9)" "validated prognostic favorable (5.11e-5)" "unprognostic (8.27e-2)" "unprognostic (6.84e-2)" "unprognostic (4.87e-2)" "unprognostic (7.53e-3)" "unprognostic (7.88e-2)" "unprognostic (1.45e-1)" "unprognostic (5.27e-2)" "unprognostic (3.15e-2)" "unprognostic (3.04e-3)" "unprognostic (1.92e-1)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (3.54e-2)" "unprognostic (3.34e-2)" "unprognostic (3.09e-2)" "unprognostic (1.04e-1)" "unprognostic (1.35e-1)" "unprognostic (3.92e-1)" MAN1A1 ENSG00000111885 "Mannosidase alpha class 1A member 1" P33908 6 119177205-119349761 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.6" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 809.4;Macrophages: 845.5;Plasma cells: 754.7;Thymocytes: 637.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 117.4" "Liver - Hepatocytes, Minor Salivary Gland - Macrophages, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 40007790.6" "Tissue enhanced" "Detected in many" "skin: 137975771.6" "CAB037058, HPA053198, HPA063561" Uncertain Supported "Golgi apparatus" NA NA 330000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 16 "Golgi apparatus" "CAB037058: , HPA053198: , HPA063561: " "unprognostic (9.84e-3)" "unprognostic (1.22e-1)" "unprognostic (1.21e-1)" "unprognostic (6.10e-2)" "unprognostic (2.90e-1)" "unprognostic (2.52e-2)" "unprognostic (1.25e-2)" "unprognostic (9.76e-3)" "unprognostic (2.52e-1)" "unprognostic (6.50e-2)" "potential prognostic favorable (9.44e-6)" "unprognostic (1.07e-1)" "unprognostic (1.07e-1)" "unprognostic (6.92e-3)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" "unprognostic (4.37e-2)" "unprognostic (1.35e-1)" "unprognostic (4.76e-3)" "unprognostic (7.48e-2)" "unprognostic (1.15e-3)" "unprognostic (4.49e-3)" "unprognostic (1.71e-1)" "unprognostic (3.37e-1)" "unprognostic (1.44e-1)" "unprognostic (2.16e-1)" "unprognostic (1.97e-1)" "unprognostic (1.25e-2)" "unprognostic (1.54e-1)" "unprognostic (3.00e-2)" "unprognostic (9.37e-2)" MANBA ENSG00000109323 "Mannosidase beta" O00462 4 102630770-102760994 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 298.1;Macrophages: 398.0;Mast cells: 282.6;Microglia: 413.5;monocytes: 536.5;Neutrophil progenitors: 569.7;Neutrophils: 711.9" "Cell type enhanced" "Detected in all" "Glial cells: 413.5;Mononuclear phagocytes: 536.5;Neutrophils: 711.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 545.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 16.6" "Group enriched" "Detected in many" 5 "dendritic cells: 5.3;granulocytes: 16.6;monocytes: 9.1" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 1079494.9;Neutrophils: 1138817.3" "Low tissue specificity" "Detected in many" "HPA037698, HPA047826, HPA053478" Approved Enhanced Vesicles NA NA 13000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 19 Vesicles "HPA037698: , HPA047826: , HPA053478: " "unprognostic (1.23e-1)" "unprognostic (6.74e-3)" "unprognostic (2.60e-1)" "unprognostic (1.34e-2)" "unprognostic (2.03e-1)" "unprognostic (6.70e-2)" "unprognostic (4.85e-3)" "unprognostic (1.40e-2)" "unprognostic (1.93e-1)" "unprognostic (1.96e-1)" "unprognostic (4.04e-3)" "unprognostic (4.09e-2)" "unprognostic (9.81e-3)" "unprognostic (2.27e-1)" "unprognostic (5.79e-2)" "unprognostic (5.56e-2)" "unprognostic (3.38e-2)" "unprognostic (2.30e-1)" "unprognostic (3.77e-2)" "unprognostic (9.64e-2)" "unprognostic (2.69e-1)" "unprognostic (1.28e-2)" MANEA "FLJ12838, mandaselin" ENSG00000172469 "Mannosidase endo-alpha" Q5SRI9 6 95577485-95609470 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 68.8;Plasma cells: 129.9" "Cell type enhanced" "Detected in all" "Plasma cells: 129.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 1678266.5" "Tissue enriched" "Detected in some" "salivary gland: 16625120.1" "HPA011046, HPA011069" Enhanced Supported "Golgi apparatus" NA NA 55000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 "Golgi apparatus" "HPA011046: , HPA011069: " "unprognostic (2.36e-2)" "unprognostic (4.81e-2)" "unprognostic (4.46e-3)" "unprognostic (7.11e-2)" "unprognostic (4.48e-2)" "unprognostic (1.35e-1)" "unprognostic (6.77e-2)" "unprognostic (5.91e-3)" "unprognostic (1.89e-1)" "unprognostic (7.02e-3)" "potential prognostic favorable (9.81e-6)" "unprognostic (2.74e-2)" "unprognostic (2.20e-1)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.70e-1)" "unprognostic (4.93e-2)" "unprognostic (2.03e-1)" "unprognostic (1.40e-1)" "unprognostic (1.18e-1)" "unprognostic (6.90e-3)" "unprognostic (1.03e-1)" "unprognostic (5.21e-2)" "unprognostic (9.63e-2)" "unprognostic (4.85e-2)" "unprognostic (2.51e-2)" "unprognostic (1.07e-1)" "unprognostic (2.04e-1)" "unprognostic (2.79e-1)" "unprognostic (9.03e-2)" "unprognostic (1.51e-1)" MANSC1 "FLJ10298, LOH12CR3" ENSG00000111261 "MANSC domain containing 1" Q9H8J5 12 12326056-12350242 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 65.5" "Cell type enhanced" "Detected in some" "Astrocytes: 10.9;Bergmann glia: 10.3;Brain excitatory neurons: 18.4;Brain inhibitory neurons: 17.8;Choroid plexus epithelial cells: 12.7;Ependymal cells: 23.6;Loop of henle epithelial cells: 7.9;Oligodendrocyte progenitor cells: 9.1;Oligodendrocytes: 13.5;Other brain neurons: 14.2;Papillary tip epithelial cells: 16.6;Podocytes: 14.7;Renal collecting duct principal cells: 18.4;Retinal pigment epithelial cells: 8.5" "Cell type enhanced" "Detected in some" "Ciliated cells: 23.6;Ductal cells: 18.4;Glial cells: 13.5;Neuronal cells: 18.4;Renal nephron cells: 16.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "neutrophil: 98.6" "Lineage enriched" "Detected in many" 39 "granulocytes: 98.6" "Cancer enriched" "Detected in many" 6 "Bile duct cancer: 134.6" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Thyrotropes, Skeletal muscle - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 382465.8;Pancreas epithelial cells: 303173.2" "Tissue enriched" "Detected in many" "salivary gland: 5624174.3" "HPA007955, HPA007956" Approved Approved "Golgi apparatus,Vesicles" NA NA 1600000 "Cluster 4: Neutrophils - Degranulation" "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 98: Neurons - Neurotransmission & signaling" 5 Vesicles "Golgi apparatus" "HPA007955: , HPA007956: " "potential prognostic favorable (3.61e-4)" "unprognostic (2.28e-3)" "unprognostic (1.75e-1)" "unprognostic (3.42e-2)" "unprognostic (4.81e-2)" "unprognostic (1.11e-1)" "unprognostic (3.86e-1)" "unprognostic (4.05e-3)" "unprognostic (1.30e-1)" "unprognostic (3.25e-2)" "potential prognostic favorable (2.17e-8)" "unprognostic (1.27e-3)" "unprognostic (2.84e-1)" "unprognostic (4.29e-2)" "unprognostic (2.48e-3)" "unprognostic (4.65e-3)" "unprognostic (3.44e-2)" "unprognostic (3.97e-1)" "unprognostic (1.52e-1)" "unprognostic (2.81e-1)" "unprognostic (2.81e-1)" "unprognostic (1.97e-2)" "unprognostic (3.76e-2)" "unprognostic (2.38e-1)" "unprognostic (3.53e-1)" "unprognostic (1.24e-2)" "unprognostic (2.41e-1)" "unprognostic (1.47e-2)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (8.05e-2)" MAOA ENSG00000189221 "Monoamine oxidase A" P21397 X 43654907-43746817 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Catecholamine metabolism, Neurotransmitter degradation" Oxidoreductase "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.3" "Cell type enhanced" "Detected in many" "Adipocytes: 378.3;Alveolar cells type 2: 420.3;Basal prostatic cells: 402.5;Enteric transient amplifying cells: 357.0;Enterocytes: 920.0;Medullary thymic epithelial cells: 355.2;Syncytiotrophoblasts: 391.3" "Cell type enhanced" "Detected in all" "Enterocytes: 920.0" "Cell type enhanced" "Detected in many" "endothelial cell: 246.7;pericyte: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 47.6;prostate cancer: 69.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cell types: 355796198.5" "Low tissue specificity" "Detected in all" "CAB009437, HPA054807, HPA059299" Enhanced Supported Mitochondria,Cytosol No No "Cluster 77: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 50: Lymphoma - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 4 Mitochondria Cytosol "CAB009437: , HPA054807: , HPA059299: " "unprognostic (7.11e-2)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (9.44e-2)" "unprognostic (1.29e-1)" "unprognostic (1.78e-2)" "unprognostic (5.28e-2)" "unprognostic (4.23e-2)" "unprognostic (3.11e-1)" "unprognostic (4.52e-2)" "potential prognostic favorable (5.86e-4)" "unprognostic (6.34e-3)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (5.16e-2)" "unprognostic (3.29e-3)" "unprognostic (2.82e-2)" "unprognostic (2.23e-1)" "unprognostic (2.68e-1)" "unprognostic (1.25e-1)" "unprognostic (8.83e-2)" "unprognostic (2.19e-1)" "unprognostic (2.44e-1)" "unprognostic (1.04e-1)" "unprognostic (2.90e-1)" "unprognostic (3.04e-3)" "unprognostic (4.16e-1)" "unprognostic (1.70e-2)" "unprognostic (6.12e-2)" "unprognostic (6.87e-2)" "unprognostic (2.75e-1)" MAP1A MAP1L ENSG00000166963 "Microtubule associated protein 1A" P78559 15 43510958-43531620 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 149.9" "Cell type enhanced" "Detected in many" "Corticotrophs: 137.2;Fallopian tube ciliated cells: 98.5;Oligodendrocytes: 77.7;pDCs: 158.3;Peritubular myoid cells: 77.4;Platelets: 329.6;Respiratory ciliated cells: 181.2;Retinal horizontal cells: 124.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 181.2;dendritic cells: 158.3;Pituitary endocrine cells: 137.2;Platelets: 329.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 29.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 61 "plasmacytoid DC: 10.5" "Lineage enriched" "Detected in single" 61 "dendritic cells: 10.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Breast - Fibroblasts, Lung - Fibroblasts_2, Prostate - Smooth muscle cells, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 361261820.2;Microglia and Neuropil: 394673681.2;Neurons: 662072913.1" "Tissue enriched" "Detected in many" "cerebral cortex: 678579967.9" "HPA039063, HPA039064, HPA066488" Enhanced Approved "Cytosol,Mid piece,Principal piece" No No 28000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 10 Cytosol "Mid piece, Principal piece" "HPA039063: , HPA039064: , HPA066488: " "unprognostic (2.36e-1)" "unprognostic (2.24e-1)" "unprognostic (1.09e-1)" "unprognostic (6.07e-2)" "unprognostic (1.73e-2)" "unprognostic (1.51e-1)" "unprognostic (1.24e-1)" "unprognostic (5.07e-2)" "unprognostic (2.44e-2)" "potential prognostic unfavorable (8.23e-4)" "unprognostic (2.44e-1)" "unprognostic (6.56e-2)" "unprognostic (1.93e-3)" "unprognostic (4.38e-2)" "unprognostic (9.01e-2)" "unprognostic (7.19e-2)" "unprognostic (2.17e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (1.46e-1)" "unprognostic (9.63e-3)" "unprognostic (6.82e-2)" "unprognostic (5.89e-3)" "unprognostic (1.77e-1)" "unprognostic (1.27e-2)" "unprognostic (2.09e-2)" "unprognostic (7.01e-2)" "unprognostic (4.59e-2)" "potential prognostic unfavorable (1.72e-5)" "unprognostic (2.33e-1)" MAP1B "MAP5, PPP1R102" ENSG00000131711 "Microtubule associated protein 1B" P46821 5 72107234-72209565 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 83.8;brain: 116.7;retina: 143.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 734.6;Cone photoreceptor cells: 813.6;Epididymal clear cells: 622.6;Other brain neurons: 747.1;Pericytes: 770.7;Pituicytes/FSCs: 728.0;Retinal ganglion cells: 838.2;Rod photoreceptor cells: 580.6;Salivary myoepithelial cells: 507.5;Schwann cells: 548.3;Sertoli cells: 551.0;Smooth muscle cells: 599.9;Vascular smooth muscle cells: 689.7" "Cell type enhanced" "Detected in many" "Glial cells: 728.0;Mural cells: 770.7;Neuronal cells: 838.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 79.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Neuroblastoma: 131.4" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 640294198.7;Microglia and Neuropil: 612093697.1;Neurons: 566265746.4;Smooth muscle cells: 329315875.5" "Tissue enriched" "Detected in all" "cerebral cortex: 1438272791.6" "CAB009792, HPA022275" Enhanced Supported Supported "Cytosol,Equatorial segment" NA NA 110000 "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 45: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 110: Mural cells - ECM organization" 64 Cytosol "Equatorial segment" "CAB009792: , HPA022275: " "unprognostic (2.61e-1)" "unprognostic (6.67e-2)" "unprognostic (2.51e-1)" "unprognostic (9.36e-2)" "unprognostic (3.37e-2)" "unprognostic (3.94e-2)" "unprognostic (2.85e-2)" "unprognostic (1.16e-2)" "unprognostic (3.37e-2)" "unprognostic (5.66e-2)" "unprognostic (6.02e-3)" "unprognostic (9.07e-2)" "unprognostic (1.71e-2)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (9.68e-3)" "unprognostic (2.73e-3)" "unprognostic (1.54e-1)" "unprognostic (7.62e-2)" "unprognostic (6.88e-2)" "unprognostic (1.61e-2)" "unprognostic (2.25e-3)" "unprognostic (4.27e-2)" "unprognostic (4.31e-2)" "unprognostic (2.10e-3)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (2.76e-2)" "unprognostic (3.26e-1)" MAP2 "MAP2A, MAP2B, MAP2C" ENSG00000078018 "Microtubule associated protein 2" P11137 2 209424047-209734147 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 259.5;retina: 379.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 576.4;Bergmann glia: 601.1;Brain excitatory neurons: 919.9;Brain inhibitory neurons: 970.9;Cone photoreceptor cells: 2546.2;Oligodendrocyte progenitor cells: 1122.0;Other brain neurons: 936.3;Pituicytes/FSCs: 1295.2;Rod photoreceptor cells: 1758.2" "Cell type enhanced" "Detected in many" "Glial cells: 1295.2;Neuronal cells: 2546.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 101.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 63.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 516846207.0;Microglia and Neuropil: 830759757.4;Neurons: 1154589723.4" "Tissue enriched" "Detected in many" "cerebral cortex: 1267416060.7" "CAB001984, HPA008273, HPA012828" Enhanced Supported Approved "Plasma membrane,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 79: Photoreceptor cells - Phototransduction" 10 Cytosol "Plasma membrane, Primary cilium, Primary cilium tip" "CAB001984: , HPA008273: , HPA012828: " "unprognostic (1.22e-1)" "unprognostic (3.02e-2)" "unprognostic (9.15e-2)" "unprognostic (1.58e-2)" "unprognostic (9.87e-2)" "unprognostic (5.13e-2)" "unprognostic (1.91e-3)" "unprognostic (1.49e-1)" "unprognostic (1.51e-2)" "validated prognostic favorable (2.05e-5)" "validated prognostic favorable (3.23e-4)" "potential prognostic unfavorable (8.85e-4)" "unprognostic (2.08e-2)" "unprognostic (9.43e-2)" "unprognostic (2.41e-2)" "unprognostic (8.47e-2)" "unprognostic (3.91e-1)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-1)" "unprognostic (3.13e-1)" "unprognostic (6.29e-2)" "unprognostic (2.80e-2)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (1.91e-1)" "unprognostic (5.14e-2)" "unprognostic (3.66e-2)" MAP2K2 "MEK2, PRKMK2" ENSG00000126934 "Mitogen-activated protein kinase kinase 2" P36507 19 4090321-4124122 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 291.0;Erythrocyte progenitors: 318.8;Esophageal apical cells: 392.2;Late spermatids: 1280.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1280.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB003835, HPA051993" Supported Enhanced "Cytosol,Mid piece,Principal piece,End piece" NA NA 130000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 122 Cytosol "Mid piece, Principal piece, End piece" "CAB003835: , HPA051993: " "unprognostic (1.46e-1)" "unprognostic (1.86e-1)" "unprognostic (1.70e-2)" "potential prognostic favorable (1.87e-4)" "unprognostic (4.76e-2)" "unprognostic (3.72e-1)" "unprognostic (1.81e-1)" "unprognostic (4.85e-2)" "unprognostic (2.14e-2)" "unprognostic (2.64e-1)" "unprognostic (7.34e-2)" "potential prognostic unfavorable (5.03e-5)" "unprognostic (2.20e-2)" "unprognostic (5.07e-3)" "potential prognostic unfavorable (1.42e-6)" "unprognostic (2.50e-2)" "unprognostic (2.98e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "unprognostic (1.97e-1)" "unprognostic (2.18e-1)" "unprognostic (6.44e-2)" "unprognostic (1.30e-1)" "unprognostic (1.49e-1)" "unprognostic (1.28e-1)" "unprognostic (3.68e-2)" "unprognostic (1.55e-1)" "unprognostic (8.17e-3)" "unprognostic (1.01e-2)" "unprognostic (3.26e-1)" "unprognostic (3.15e-2)" MAP2K5 "HsT17454, MAPKK5, MEK5, PRKMK5" ENSG00000137764 "Mitogen-activated protein kinase kinase 5" Q13163 15 67542703-67807117 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1077551.3;Large ducts: 505507.0" "Group enriched" "Detected in some" 124 "cerebral cortex: 13673.0;lymphoid tissue: 11109.1" "CAB022094, HPA027347, HPA027755" Supported Approved "Nucleoli,Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 26 "Microtubules, Primary cilium" "Nucleoli, Cytokinetic bridge, Basal body" "CAB022094: , HPA027347: , HPA027755: " "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (1.16e-1)" "unprognostic (6.58e-2)" "unprognostic (3.33e-2)" "unprognostic (1.86e-1)" "unprognostic (2.09e-2)" "unprognostic (5.44e-3)" "unprognostic (1.39e-1)" "unprognostic (2.62e-1)" "validated prognostic favorable (3.83e-6)" "validated prognostic favorable (2.52e-5)" "unprognostic (2.09e-1)" "unprognostic (2.15e-1)" "unprognostic (4.68e-3)" "unprognostic (7.37e-2)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (2.36e-1)" "unprognostic (2.34e-1)" "unprognostic (2.13e-1)" "unprognostic (2.06e-3)" "unprognostic (9.80e-2)" "unprognostic (6.09e-2)" "unprognostic (8.46e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (3.83e-1)" "unprognostic (1.69e-2)" "unprognostic (3.90e-1)" MAP3K11 "MEKK11, MLK3, PTK1, SPRK" ENSG00000173327 "Mitogen-activated protein kinase kinase kinase 11" Q16584 11 65597756-65615382 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 106.5;Late spermatids: 110.3;Neutrophils: 128.7" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "endothelial cell: 62.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 706346.6" "Group enriched" "Detected in some" 3271 "lung: 288882.1;lymphoid tissue: 365262.6" CAB010165 Approved Supported "Centriolar satellite,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 17 "Centriolar satellite, Cytosol" "CAB010165: " "unprognostic (3.93e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (1.41e-1)" "unprognostic (2.39e-1)" "unprognostic (9.67e-2)" "unprognostic (1.03e-1)" "unprognostic (5.18e-2)" "unprognostic (3.44e-1)" "unprognostic (1.61e-1)" "unprognostic (2.47e-2)" "unprognostic (7.53e-2)" "unprognostic (3.74e-2)" "unprognostic (2.34e-3)" "unprognostic (3.46e-1)" "unprognostic (8.23e-2)" "unprognostic (6.91e-2)" "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (8.33e-4)" "unprognostic (5.29e-2)" "unprognostic (6.03e-2)" "unprognostic (7.24e-2)" "unprognostic (5.38e-2)" "unprognostic (1.31e-1)" "unprognostic (4.15e-1)" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (2.87e-1)" "unprognostic (8.87e-2)" MAP3K5 "ASK1, MAPKKK5, MEKK5" ENSG00000197442 "Mitogen-activated protein kinase kinase kinase 5" Q99683 6 136557046-136793097 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Immunity, Innate immunity, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 83.2" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 2392.7;Neutrophils: 1381.5;Pituicytes/FSCs: 1412.2;Prostatic glandular cells: 895.0" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 2392.7;Glial cells: 1412.2;Neutrophils: 1381.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB007824, HPA063245" Supported Supported Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 102 Cytosol "CAB007824: , HPA063245: " "unprognostic (1.84e-2)" "unprognostic (1.09e-1)" "unprognostic (3.71e-1)" "unprognostic (6.58e-2)" "unprognostic (4.73e-2)" "unprognostic (1.70e-1)" "unprognostic (2.11e-1)" "unprognostic (3.26e-1)" "unprognostic (1.63e-3)" "unprognostic (2.45e-1)" "potential prognostic favorable (2.25e-6)" "unprognostic (2.27e-2)" "unprognostic (1.48e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (7.48e-4)" "unprognostic (1.50e-1)" "unprognostic (1.95e-2)" "unprognostic (7.31e-2)" "unprognostic (4.66e-3)" "unprognostic (2.03e-2)" "unprognostic (4.71e-2)" "unprognostic (1.11e-3)" "unprognostic (3.01e-1)" "unprognostic (2.43e-1)" "unprognostic (4.11e-2)" "unprognostic (6.78e-2)" "unprognostic (1.26e-1)" "unprognostic (3.71e-1)" "unprognostic (2.25e-1)" "unprognostic (5.47e-2)" "unprognostic (1.43e-2)" MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587086 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 1690407.5" "Low tissue specificity" "Detected in many" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 7: Non-specific - Transcription" 108 Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: , HPA075335: " "unprognostic (1.28e-1)" "unprognostic (1.26e-2)" "unprognostic (1.16e-3)" "unprognostic (6.96e-3)" "unprognostic (7.22e-2)" "unprognostic (4.36e-2)" "unprognostic (1.62e-1)" "unprognostic (3.48e-2)" "unprognostic (3.03e-1)" "unprognostic (7.73e-3)" "unprognostic (6.42e-2)" "unprognostic (1.22e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (6.81e-5)" "unprognostic (4.18e-2)" "unprognostic (2.31e-2)" "unprognostic (1.06e-1)" "unprognostic (1.67e-1)" "unprognostic (1.17e-1)" "unprognostic (2.32e-1)" "unprognostic (3.44e-1)" "unprognostic (7.60e-2)" "unprognostic (1.02e-2)" "unprognostic (3.75e-1)" "unprognostic (1.74e-2)" "unprognostic (7.38e-2)" "unprognostic (3.01e-2)" "unprognostic (7.14e-2)" "unprognostic (4.73e-1)" "unprognostic (2.87e-1)" "unprognostic (1.74e-1)" MAP4 ENSG00000047849 "Microtubule associated protein 4" P27816 3 47850690-48089272 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 890.0;skeletal muscle: 562.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1467.7;Myonuclei: 2090.4;Thymic myoid cells: 964.0" "Cell type enhanced" "Detected in all" "Myocytes: 2090.4;Neuronal cells: 1467.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA038149, HPA038150" Enhanced Approved "Plasma membrane,Microtubules,Primary cilium,Basal body,Cytosol,Acrosome,Equatorial segment" NA NA 600000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 75 "Plasma membrane, Microtubules, Primary cilium, Cytosol" "Basal body, Acrosome, Equatorial segment" "HPA038149: , HPA038150: " "unprognostic (3.70e-2)" "unprognostic (1.77e-1)" "unprognostic (9.34e-2)" "unprognostic (6.10e-3)" "unprognostic (1.09e-1)" "unprognostic (7.42e-2)" "unprognostic (2.75e-1)" "unprognostic (5.11e-2)" "unprognostic (2.74e-1)" "unprognostic (3.76e-3)" "unprognostic (3.31e-3)" "unprognostic (3.68e-2)" "potential prognostic favorable (6.40e-4)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (1.26e-2)" "unprognostic (8.11e-2)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (3.61e-2)" "unprognostic (7.13e-2)" "unprognostic (3.87e-2)" "unprognostic (9.64e-2)" "unprognostic (6.07e-2)" "unprognostic (7.45e-2)" "unprognostic (6.59e-2)" "unprognostic (1.69e-1)" "unprognostic (2.26e-3)" "unprognostic (3.22e-1)" "unprognostic (9.14e-2)" "unprognostic (1.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.90e-2)" MAP6D1 "FLJ12748, SL21" ENSG00000180834 "MAP6 domain containing 1" Q9H9H5 3 183815922-183825594 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 120.4" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 102.1" "Cell type enriched" "Detected in some" 4 "Glial cells: 102.1" "Group enriched" "Detected in all" 4 "committed oligodendrocyte precursor: 50.6;oligodendrocyte: 129.3;upper rhombic lip: 40.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 14.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53257 "Astrocytes and Neuropil: 6494771.2;Microglia and Neuropil: 4119232.7;Neurons: 5363159.6" "Tissue enriched" "Detected in single" 46139 "cerebral cortex: 4613868.1" HPA037991 Enhanced Supported Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 27: Breast cancer - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" Cytosol "HPA037991: " "potential prognostic unfavorable (3.70e-4)" "unprognostic (3.89e-2)" "unprognostic (2.25e-1)" "unprognostic (1.80e-1)" "unprognostic (1.04e-2)" "unprognostic (3.75e-1)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.91e-2)" "unprognostic (4.77e-3)" "unprognostic (2.05e-1)" "unprognostic (3.11e-3)" "unprognostic (8.29e-2)" "unprognostic (2.22e-2)" "unprognostic (6.53e-2)" "unprognostic (4.69e-2)" "unprognostic (6.38e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-2)" "unprognostic (2.02e-1)" "unprognostic (6.85e-2)" "unprognostic (2.21e-2)" MAP7D3 FLJ12649 ENSG00000129680 "MAP7 domain containing 3" Q8IWC1 X 136213220-136256482 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 128.0;Early spermatids: 191.3;Extravillous trophoblasts: 159.0;Late primary spermatocytes: 126.9;Late spermatids: 280.5;Oocytes: 142.8;Sertoli cells: 106.2;Undifferentiated spermatogonia: 100.2;Vascular smooth muscle cells: 112.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 280.5;Trophoblast cells: 159.0" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 59.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Endothelial cells" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Fallopian tube cells: 645976.7;Oocytes: 2077195.2" "Group enriched" "Detected in some" 4661 "fallopian tube: 500408.7;lymphoid tissue: 548396.9;ovary: 349413.5" "HPA035598, HPA058101" Approved Uncertain "Nucleoplasm,Plasma membrane,Primary cilium,Centrosome,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 16 "Plasma membrane, Centrosome" "Nucleoplasm, Primary cilium, Basal body" "HPA035598: , HPA058101: " "unprognostic (3.40e-1)" "unprognostic (1.69e-1)" "unprognostic (7.51e-3)" "unprognostic (5.53e-2)" "unprognostic (2.12e-3)" "unprognostic (1.77e-2)" "unprognostic (3.17e-2)" "unprognostic (3.18e-1)" "unprognostic (1.27e-2)" "unprognostic (7.59e-2)" "potential prognostic favorable (4.16e-4)" "unprognostic (4.81e-2)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.36e-4)" "unprognostic (5.37e-2)" "unprognostic (1.00e-1)" "unprognostic (6.98e-2)" "unprognostic (1.74e-1)" "unprognostic (9.79e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (3.23e-1)" "unprognostic (2.97e-2)" "unprognostic (6.89e-2)" "unprognostic (8.19e-2)" "unprognostic (3.48e-1)" "unprognostic (4.05e-2)" "unprognostic (4.42e-3)" "unprognostic (3.95e-1)" "unprognostic (1.03e-2)" "unprognostic (1.54e-2)" MAPK1 "ERK, ERK2, MAPK2, p41mapk, PRKM1, PRKM2" ENSG00000100030 "Mitogen-activated protein kinase 1" P28482 22 21759657-21867680 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "DNA-binding, Kinase, Repressor, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 608.3;Neutrophil progenitors: 707.3;Neutrophils: 1044.8" "Cell type enhanced" "Detected in all" "Mast cells: 608.3;Neutrophils: 1044.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 243012851.9" "Tissue enriched" "Detected in all" "cerebral cortex: 258964271.6" "HPA003995, CAB004229, HPA005700, HPA030069, CAB079932, CAB079933" Enhanced Supported "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA 270000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 193 Nucleoplasm "Microtubules, Primary cilium, Primary cilium tip, Basal body, Cytosol" "CAB004229: , CAB079932: , CAB079933: , HPA003995: , HPA005700: , HPA030069: " "unprognostic (6.01e-2)" "unprognostic (4.30e-2)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (1.51e-2)" "unprognostic (2.84e-1)" "unprognostic (2.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (1.27e-6)" "unprognostic (4.91e-3)" "unprognostic (1.33e-1)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (1.52e-1)" "unprognostic (9.62e-2)" "unprognostic (9.27e-2)" "unprognostic (8.98e-3)" "unprognostic (1.70e-1)" "unprognostic (9.52e-3)" "unprognostic (9.83e-3)" "unprognostic (2.45e-1)" "unprognostic (1.56e-1)" "unprognostic (1.40e-2)" "unprognostic (9.44e-2)" "unprognostic (5.94e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (7.79e-2)" "unprognostic (2.30e-1)" MAPK12 "ERK6, p38gamma, PRKM12, SAPK-3, SAPK3" ENSG00000188130 "Mitogen-activated protein kinase 12" P53778 22 50245450-50261716 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 280.4;tongue: 112.9" "Cell type enhanced" "Detected in many" "Astrocytes: 31.8;Bergmann glia: 16.3;Corticotrophs: 17.3;Epididymal principal cells: 33.5;Gonadotrophs: 26.2;Megakaryocyte progenitors: 17.3;Megakaryocytes: 18.5;Myonuclei: 25.4;Thymic myoid cells: 27.2;Vascular endothelial cells: 19.4" "Cell type enhanced" "Detected in many" "Glial cells: 31.8;Reproductive supporting cells: 33.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Skin - Endothelial cells" "Region enhanced" "Detected in all" "cerebellum: 31.6" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 16649281.4" "Group enriched" "Detected in some" 5008 "cerebral cortex: 229665.6;skeletal muscle: 771852.8" "CAB025483, HPA054562" Enhanced Approved "Nuclear speckles,Cytosol" NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 19 "Nuclear speckles" Cytosol "CAB025483: , HPA054562: " "unprognostic (8.62e-2)" "unprognostic (2.92e-2)" "unprognostic (2.62e-2)" "unprognostic (9.39e-2)" "unprognostic (1.23e-2)" "unprognostic (1.68e-2)" "unprognostic (8.25e-2)" "unprognostic (2.80e-3)" "unprognostic (5.07e-3)" "unprognostic (4.20e-3)" "unprognostic (8.04e-2)" "unprognostic (7.32e-2)" "unprognostic (1.08e-1)" "unprognostic (7.93e-3)" "unprognostic (3.52e-2)" "unprognostic (1.53e-3)" "unprognostic (5.43e-2)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "unprognostic (2.53e-2)" "unprognostic (1.98e-1)" "unprognostic (1.23e-1)" "unprognostic (1.47e-3)" "unprognostic (2.55e-1)" "unprognostic (5.92e-3)" "unprognostic (7.77e-2)" "unprognostic (2.51e-1)" "unprognostic (8.00e-2)" "unprognostic (2.68e-1)" "unprognostic (1.24e-2)" "unprognostic (1.53e-1)" MAPK14 "CSBP1, CSBP2, CSPB1, Mxi2, p38, PRKM14, PRKM15" ENSG00000112062 "Mitogen-activated protein kinase 14" Q16539 6 36027782-36111236 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Monocyte progenitors: 731.2;Neutrophil progenitors: 1492.2;Neutrophils: 2779.7" "Group enriched" "Detected in all" 5 "Mononuclear phagocytes: 731.2;Neutrophils: 2779.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 78.0;neutrophil: 25.8" "Lineage enriched" "Detected in all" 7 "granulocytes: 78.0" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 24173947.9" "Low tissue specificity" "Detected in all" "CAB010285, CAB040578, HPA051825" Approved Supported "Nuclear speckles,Cytosol" NA NA 650000 "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 31: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 121 "Nuclear speckles" Cytosol "CAB010285: , CAB040578: , HPA051825: " "unprognostic (2.70e-2)" "unprognostic (1.33e-1)" "unprognostic (6.38e-2)" "unprognostic (8.86e-3)" "unprognostic (6.92e-2)" "unprognostic (2.51e-3)" "unprognostic (3.78e-1)" "unprognostic (1.62e-1)" "unprognostic (9.50e-2)" "potential prognostic unfavorable (2.90e-4)" "potential prognostic favorable (7.79e-5)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (1.35e-1)" "unprognostic (6.04e-2)" "unprognostic (9.57e-2)" "unprognostic (6.94e-2)" "unprognostic (5.39e-2)" "unprognostic (2.40e-3)" "unprognostic (1.72e-2)" "unprognostic (3.96e-3)" "unprognostic (6.07e-2)" "unprognostic (1.97e-3)" "unprognostic (2.20e-1)" "unprognostic (5.49e-3)" "unprognostic (6.84e-3)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (4.02e-1)" MAPK3 "ERK1, p44erk1, p44mapk, PRKM3" ENSG00000102882 "Mitogen-activated protein kinase 3" P27361 16 30114105-30123506 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 268.7;Early spermatids: 326.3;Enterocytes: 226.1;Esophageal apical cells: 543.4;Extravillous trophoblasts: 188.0;Foveolar cells: 172.9;Goblet cells: 190.0;Late spermatids: 229.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 543.4;Enterocytes: 268.7;Spermatogenic cell types: 326.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 49.2;neutrophil: 21.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 49.2" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 206808434.0" "CAB002683, HPA003995, HPA005700, HPA030069" Approved Supported "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA 92000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 110 Nucleoplasm "Microtubules, Primary cilium, Primary cilium tip, Basal body, Cytosol" "CAB002683: , HPA003995: , HPA005700: , HPA030069: " "unprognostic (1.23e-1)" "unprognostic (3.99e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-1)" "unprognostic (9.14e-2)" "unprognostic (2.28e-1)" "unprognostic (1.90e-1)" "unprognostic (3.04e-1)" "unprognostic (2.41e-1)" "unprognostic (7.32e-2)" "potential prognostic favorable (4.11e-7)" "unprognostic (3.91e-3)" "unprognostic (2.61e-2)" "validated prognostic unfavorable (7.45e-5)" "validated prognostic unfavorable (3.39e-4)" "unprognostic (4.37e-2)" "unprognostic (4.88e-2)" "unprognostic (4.41e-3)" "unprognostic (4.10e-2)" "unprognostic (9.34e-2)" "unprognostic (5.80e-2)" "unprognostic (1.06e-2)" "unprognostic (5.11e-2)" "unprognostic (2.41e-1)" "unprognostic (1.64e-1)" "unprognostic (1.92e-2)" "unprognostic (1.28e-1)" "unprognostic (1.72e-1)" "unprognostic (2.78e-1)" "unprognostic (9.64e-2)" "unprognostic (9.83e-2)" MAPK4 "Erk3-related, Erk4, PRKM4" ENSG00000141639 "Mitogen-activated protein kinase 4" P31152 18 50560087-50731826 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.2;parathyroid gland: 47.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 215.7;Astrocytes: 388.3;Bergmann glia: 489.0;Brain inhibitory neurons: 190.1;Cardiomyocytes: 189.3;Choroid plexus epithelial cells: 533.1;Ependymal cells: 229.4;Müller glia: 345.3;Pituicytes/FSCs: 1914.2" "Group enriched" "Detected in many" 5 "Ciliated cells: 533.1;Glial cells: 1914.2" "Cell type enhanced" "Detected in many" "astrocyte: 509.5;Bergmann glia: 522.4" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 38.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 18.0;Rhabdoid: 9.6" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Kidney - Ascending Loop of Henle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 1275802.9" "Tissue enriched" "Detected in single" 1299 "cerebral cortex: 129858.3" HPA007461 Approved "Nucleoplasm,Golgi apparatus,Midbody,Cytosol" Yes NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 23 "Nucleoplasm, Golgi apparatus" "Midbody, Cytosol" "HPA007461: " "unprognostic (1.22e-1)" "unprognostic (5.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.88e-1)" "unprognostic (1.50e-1)" "unprognostic (1.89e-1)" "unprognostic (5.56e-2)" "unprognostic (1.76e-3)" "unprognostic (1.40e-2)" "unprognostic (3.80e-2)" "potential prognostic favorable (6.32e-4)" "unprognostic (8.22e-2)" "unprognostic (4.93e-3)" "unprognostic (1.07e-1)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (4.54e-4)" "unprognostic (6.21e-3)" "unprognostic (8.78e-3)" MAPK6 "ERK3, HsT17250, p97MAPK, PRKM6" ENSG00000069956 "Mitogen-activated protein kinase 6" Q16659 15 51952106-52067375 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 401.0;Mast cells: 378.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1500 "Oocytes: 91430.3;Pancreatic islets: 208583.8" "Not detected" "Not detected" "CAB005184, HPA030262, HPA047825" Approved Supported Approved "Microtubules,Primary cilium,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 37 Cytosol "Microtubules, Primary cilium" "CAB005184: , HPA030262: , HPA047825: " "unprognostic (1.07e-1)" "unprognostic (3.05e-2)" "unprognostic (9.56e-2)" "unprognostic (1.61e-2)" "unprognostic (3.95e-2)" "unprognostic (6.03e-2)" "unprognostic (3.66e-1)" "unprognostic (4.14e-1)" "unprognostic (7.79e-2)" "unprognostic (1.55e-2)" "unprognostic (5.65e-2)" "unprognostic (1.55e-1)" "unprognostic (5.81e-2)" "unprognostic (4.09e-2)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (1.82e-3)" "unprognostic (4.06e-1)" "unprognostic (1.84e-1)" "unprognostic (3.90e-1)" "unprognostic (4.82e-2)" "unprognostic (5.92e-3)" "unprognostic (1.43e-2)" "unprognostic (1.50e-1)" "unprognostic (7.25e-2)" "unprognostic (4.70e-2)" "unprognostic (7.60e-2)" "unprognostic (1.67e-1)" "unprognostic (2.20e-1)" "unprognostic (1.34e-2)" "unprognostic (2.17e-1)" MAPK8IP3 "JIP3, JSAP1, KIAA1066, syd" ENSG00000138834 "Mitogen-activated protein kinase 8 interacting protein 3" Q9UPT6 16 1706166-1770351 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 184.1" "Cell type enhanced" "Detected in many" "Retinal ganglion cells: 239.5;Retinal horizontal cells: 228.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 8410956.8;Microglia and Neuropil: 7297848.1" "Group enriched" "Detected in some" "cerebral cortex: 14998885.8;heart muscle: 6701267.4" "CAB005580, HPA041785, HPA069311" Approved Approved "Vesicles,Cytokinetic bridge,Centrosome,Cytosol" Yes NA "Cluster 19: Eosinophils - Unknown function" "Cluster 71: Cerebellum - Nervous system development" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 51: Secretory epithelial cells - Mixed function" 24 Vesicles "Cytokinetic bridge, Centrosome, Cytosol" "CAB005580: , HPA041785: , HPA069311: " "unprognostic (4.99e-2)" "unprognostic (5.45e-1)" "unprognostic (7.62e-2)" "unprognostic (5.62e-2)" "unprognostic (7.16e-2)" "unprognostic (2.69e-2)" "unprognostic (3.39e-1)" "unprognostic (5.50e-3)" "unprognostic (1.27e-2)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (2.27e-6)" "unprognostic (8.05e-2)" "unprognostic (4.06e-2)" "unprognostic (2.98e-2)" "unprognostic (4.82e-1)" "unprognostic (4.41e-2)" "unprognostic (1.02e-1)" "unprognostic (4.07e-2)" "unprognostic (2.87e-3)" "unprognostic (2.42e-1)" "unprognostic (4.19e-2)" "unprognostic (1.20e-2)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (1.73e-2)" "unprognostic (2.18e-1)" "unprognostic (1.64e-2)" "unprognostic (5.40e-2)" "unprognostic (3.49e-1)" "unprognostic (3.91e-1)" "unprognostic (2.22e-1)" "unprognostic (9.54e-2)" MAPKAP1 "MGC2745, MIP1, SIN1" ENSG00000119487 "MAPK associated protein 1" Q9BPZ7 9 125437393-125707234 "Predicted intracellular proteins" "Stress response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 5357777.4;Granulosa cells: 3372705.4" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8051985.5" "HPA029091, HPA029092" Supported Approved "Nucleoplasm,Primary cilium,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 29 Nucleoplasm "Primary cilium, Cytosol" "HPA029091: , HPA029092: " "unprognostic (7.46e-2)" "unprognostic (1.60e-2)" "unprognostic (2.35e-2)" "unprognostic (5.98e-2)" "unprognostic (2.98e-1)" "unprognostic (8.50e-3)" "unprognostic (3.80e-1)" "unprognostic (8.39e-2)" "unprognostic (1.13e-1)" "unprognostic (1.73e-2)" "potential prognostic favorable (6.63e-4)" "unprognostic (4.04e-2)" "unprognostic (1.44e-2)" "potential prognostic unfavorable (5.82e-4)" "unprognostic (1.71e-3)" "unprognostic (5.30e-3)" "unprognostic (2.01e-2)" "unprognostic (2.06e-1)" "unprognostic (4.32e-3)" "unprognostic (2.38e-2)" "unprognostic (1.81e-1)" "unprognostic (3.15e-2)" "unprognostic (9.91e-2)" "unprognostic (3.40e-1)" "unprognostic (3.32e-1)" "unprognostic (5.15e-2)" "unprognostic (3.73e-1)" "unprognostic (2.17e-2)" "unprognostic (2.77e-1)" "unprognostic (3.26e-1)" "unprognostic (3.32e-1)" MAPKAPK5 "MK5, PRAK" ENSG00000089022 "MAPK activated protein kinase 5" Q8IW41 12 111842228-111902222 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004546, HPA015515" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 10 Nucleoplasm Cytosol "CAB004546: , HPA015515: " "unprognostic (1.28e-1)" "unprognostic (2.11e-2)" "unprognostic (8.48e-3)" "unprognostic (9.24e-2)" "unprognostic (6.92e-2)" "unprognostic (1.85e-1)" "unprognostic (4.10e-2)" "unprognostic (9.21e-2)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (1.21e-3)" "unprognostic (4.14e-2)" "unprognostic (6.80e-3)" "validated prognostic unfavorable (9.68e-10)" "validated prognostic unfavorable (1.00e-5)" "unprognostic (1.39e-2)" "unprognostic (1.89e-3)" "unprognostic (1.99e-2)" "unprognostic (8.89e-2)" "unprognostic (1.82e-1)" "unprognostic (1.10e-1)" "unprognostic (2.09e-1)" "unprognostic (2.57e-2)" "unprognostic (1.93e-2)" "potential prognostic favorable (8.11e-4)" "unprognostic (3.11e-1)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" "unprognostic (1.23e-1)" "unprognostic (6.86e-2)" "unprognostic (2.74e-2)" MAPKBP1 "KIAA0596, NPHP20" ENSG00000137802 "Mitogen-activated protein kinase binding protein 1" O60336 15 41774434-41827855 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 69.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 256.6;Cone photoreceptor cells: 335.4;Sertoli cells: 216.1;Suprabasal keratinocytes: 222.2" "Cell type enhanced" "Detected in all" "Basal cells: 256.6;Neuronal cells: 335.4;Suprabasal cells: 222.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1041516.6;Keratinocytes: 771329.1" "Group enriched" "Detected in some" 316 "fallopian tube: 32064.5;lymphoid tissue: 28560.9;ovary: 34269.0" "HPA030832, HPA030833" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 51 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA030832: , HPA030833: " "unprognostic (1.20e-1)" "unprognostic (5.34e-2)" "unprognostic (1.02e-1)" "unprognostic (4.11e-2)" "unprognostic (1.10e-1)" "unprognostic (2.04e-1)" "unprognostic (1.55e-2)" "potential prognostic favorable (8.10e-4)" "unprognostic (4.15e-1)" "unprognostic (3.41e-2)" "unprognostic (3.25e-3)" "unprognostic (2.27e-3)" "unprognostic (1.26e-1)" "unprognostic (8.49e-3)" "unprognostic (3.74e-1)" "unprognostic (3.71e-2)" "unprognostic (9.55e-2)" "unprognostic (2.26e-1)" "unprognostic (6.03e-3)" "unprognostic (1.18e-3)" "unprognostic (3.42e-2)" "unprognostic (6.59e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (6.39e-2)" "unprognostic (1.61e-1)" "unprognostic (2.29e-3)" "unprognostic (1.71e-1)" "unprognostic (3.35e-2)" "unprognostic (2.47e-1)" "unprognostic (5.79e-2)" "unprognostic (2.18e-2)" MAPRE1 EB1 ENSG00000101367 "Microtubule associated protein RP/EB family member 1" Q15691 20 32819954-32850405 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 278.2;Neutrophils: 304.3;Platelets: 287.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA003600, CAB009337, CAB019391" Supported Supported "Centrosome,Basal body,Cytosol" NA NA 4500000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 386 "Centrosome, Cytosol" "Basal body" "CAB009337: , CAB019391: , HPA003600: " "unprognostic (1.24e-1)" "unprognostic (1.29e-1)" "unprognostic (5.79e-2)" "unprognostic (1.21e-3)" "unprognostic (7.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (1.96e-1)" "unprognostic (7.07e-2)" "unprognostic (5.76e-3)" "potential prognostic favorable (3.21e-5)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (8.68e-3)" "unprognostic (1.98e-2)" "unprognostic (3.97e-3)" "unprognostic (7.87e-2)" "unprognostic (9.30e-2)" "unprognostic (2.52e-2)" "unprognostic (1.30e-3)" "unprognostic (2.10e-2)" "unprognostic (8.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" "unprognostic (9.23e-2)" "unprognostic (1.11e-1)" "unprognostic (1.08e-2)" "unprognostic (2.39e-1)" "unprognostic (7.10e-3)" "unprognostic (5.12e-2)" MARCHF1 "FLJ20668, MARCH-I, MARCH1, RNF171" ENSG00000145416 "Membrane associated ring-CH-type finger 1" Q8TCQ1 4 163524298-164384050 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 29.3;retina: 21.3" "Cell type enhanced" "Detected in many" "B-cells: 788.7;Cone photoreceptor cells: 2192.3;Corticotrophs: 581.3;Kupffer cells: 563.7;Lactotrophs: 1336.2;Oligodendrocyte progenitor cells: 1400.5;Oligodendrocytes: 1945.9;Other brain neurons: 787.2;Retinal amacrine cells: 608.6;Rod photoreceptor cells: 2793.1" "Cell type enhanced" "Detected in many" "Glial cells: 1945.9;Neuronal cells: 2793.1;Pituitary endocrine cells: 1336.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 94 "classical monocyte: 41.8;eosinophil: 25.5;intermediate monocyte: 41.0;memory B-cell: 42.4;myeloid DC: 44.2;naive B-cell: 35.9;non-classical monocyte: 45.6;plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014600, HPA048024" Uncertain Supported "Endoplasmic reticulum,Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 109: Neurons - Neuronal signaling" 2 Vesicles "Endoplasmic reticulum, Golgi apparatus" "HPA014600: , HPA048024: " "unprognostic (7.88e-3)" "unprognostic (6.06e-2)" "unprognostic (4.79e-2)" "unprognostic (2.95e-2)" "unprognostic (6.81e-2)" "unprognostic (2.35e-1)" "unprognostic (5.98e-3)" "unprognostic (7.91e-2)" "unprognostic (4.01e-1)" "unprognostic (8.76e-2)" "unprognostic (1.11e-1)" "unprognostic (1.84e-1)" "unprognostic (1.46e-2)" "unprognostic (3.18e-2)" "unprognostic (4.25e-2)" "unprognostic (3.76e-1)" "unprognostic (1.41e-1)" "unprognostic (3.06e-2)" "unprognostic (2.09e-1)" "unprognostic (6.37e-2)" "unprognostic (7.34e-2)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" "unprognostic (7.25e-2)" "unprognostic (7.25e-2)" "unprognostic (2.73e-2)" "unprognostic (4.65e-2)" "unprognostic (1.34e-1)" MARCHF7 "AXOT, MARCH-VII, MARCH7, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 586.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Capillaries: 505470.0" "Not detected" "Not detected" "HPA014275, HPA022152" Enhanced Approved "Plasma membrane,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 24: Neutrophils - Innate immunity signal integration" 42 "Plasma membrane, Cytosol" "Basal body" "HPA014275: , HPA022152: " "unprognostic (4.47e-2)" "unprognostic (1.48e-1)" "unprognostic (7.71e-2)" "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "unprognostic (3.28e-1)" "unprognostic (3.04e-2)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.90e-4)" "potential prognostic favorable (9.41e-5)" "unprognostic (2.49e-2)" "unprognostic (8.63e-2)" "unprognostic (4.66e-3)" "unprognostic (2.34e-1)" "unprognostic (4.48e-2)" "unprognostic (3.78e-2)" "unprognostic (1.47e-1)" "unprognostic (5.73e-2)" "unprognostic (1.60e-3)" "unprognostic (5.14e-3)" "potential prognostic unfavorable (7.63e-4)" "unprognostic (1.05e-1)" "unprognostic (1.27e-1)" "unprognostic (6.74e-3)" "unprognostic (8.34e-2)" "unprognostic (1.22e-2)" "unprognostic (1.94e-1)" "unprognostic (4.88e-2)" "unprognostic (9.44e-2)" MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857345-113863475 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 931.9;Neutrophils: 1059.3;Urothelial cells: 964.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 931.9;Barrier epithelial cells: 964.5;Neutrophils: 1059.3" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 489.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 12.8;neutrophil: 18.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 158601611.4;Microglia and Neuropil: 119564104.1" "Tissue enhanced" "Detected in all" "cerebral cortex: 961792113.3" "CAB022062, HPA067595, HPA069443" Enhanced Supported "Nucleoplasm,Plasma membrane,Primary cilium,Cytosol" NA NA 8500000 "Cluster 40: Monocytes - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 22: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 21 "Plasma membrane" "Nucleoplasm, Primary cilium, Cytosol" "CAB022062: , HPA067595: , HPA069443: " "unprognostic (6.09e-3)" "unprognostic (1.12e-1)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (7.71e-2)" "unprognostic (2.32e-1)" "unprognostic (5.78e-2)" "unprognostic (1.94e-2)" "unprognostic (9.95e-3)" "potential prognostic favorable (3.38e-4)" "unprognostic (9.98e-2)" "unprognostic (8.23e-2)" "validated prognostic unfavorable (1.23e-9)" "validated prognostic unfavorable (8.92e-5)" "unprognostic (6.66e-3)" "unprognostic (3.11e-3)" "unprognostic (1.91e-1)" "unprognostic (5.11e-2)" "unprognostic (1.41e-2)" "unprognostic (3.61e-1)" "unprognostic (2.51e-2)" "unprognostic (8.02e-2)" "unprognostic (6.57e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (5.52e-2)" "unprognostic (6.03e-2)" "unprognostic (9.05e-2)" MARCKSL1 "F52, MacMARCKS, MLP, MLP1" ENSG00000175130 "MARCKS like 1" P49006 1 32333839-32336233 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1097.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 511.5;Breast secretory cells: 628.3;Enteric stem cells: 558.6;Granulosa cells: 862.9;Neuroendocrine cells: 524.3;Oligodendrocytes: 476.7;Ovarian stromal cells: 606.1;Peritubular myoid cells: 534.7;Tuft cells: 1026.0" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 862.9;Secretory gland support: 1026.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 298.1;oligodendrocyte: 724.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "eosinophil: 253.1" "Lineage enriched" "Detected in all" 8 "granulocytes: 253.1" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 19238583.3;Granulosa cells: 34873834.7" "Group enriched" "Detected in all" "cerebral cortex: 58238497.1;ovary: 115451952.0" "CAB020787, HPA030528" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes Yes 420000 "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 15: Non-specific - Protein processing" 18 "Plasma membrane" "Endoplasmic reticulum, Cytokinetic bridge, Mitotic spindle, Primary cilium" "CAB020787: , HPA030528: " "unprognostic (1.81e-2)" "unprognostic (4.32e-1)" "unprognostic (5.61e-2)" "unprognostic (1.28e-1)" "unprognostic (7.66e-2)" "unprognostic (1.30e-1)" "unprognostic (7.78e-2)" "potential prognostic favorable (6.33e-5)" "unprognostic (3.58e-2)" "unprognostic (9.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.16e-2)" "unprognostic (2.99e-1)" "validated prognostic unfavorable (8.35e-7)" "validated prognostic unfavorable (7.27e-6)" "unprognostic (7.80e-2)" "unprognostic (3.00e-3)" "unprognostic (2.25e-1)" "unprognostic (1.75e-1)" "unprognostic (4.63e-2)" "unprognostic (3.18e-2)" "unprognostic (3.47e-1)" "unprognostic (2.12e-3)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (1.05e-1)" "unprognostic (3.25e-2)" "unprognostic (4.32e-2)" "unprognostic (3.15e-2)" "unprognostic (8.37e-3)" MARVELD3 MRVLDC3 ENSG00000140832 "MARVEL domain containing 3" Q96A59 16 71626161-71642114 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 31.2" "Cell type enhanced" "Detected in many" "Colonocytes: 151.6;Enteric stem cells: 69.1;Enteric transient amplifying cells: 74.7;Enterocytes: 274.3;Goblet cells: 91.6;Tuft cells: 69.2" "Cell type enhanced" "Detected in many" "Enterocytes: 274.3" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 9.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 33 "fallopian tube: 3297.8" "HPA043514, HPA045471" Approved "Vesicles,Intermediate filaments" No NA "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Vesicles "Intermediate filaments" "HPA043514: , HPA045471: " "unprognostic (6.25e-3)" "unprognostic (2.85e-1)" "unprognostic (3.75e-2)" "unprognostic (1.23e-2)" "unprognostic (2.47e-1)" "unprognostic (1.91e-1)" "unprognostic (1.29e-1)" "unprognostic (3.64e-1)" "unprognostic (2.95e-2)" "unprognostic (3.98e-2)" "potential prognostic favorable (1.51e-5)" "unprognostic (1.37e-3)" "unprognostic (1.00e-3)" "unprognostic (2.17e-1)" "unprognostic (5.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.29e-1)" "unprognostic (1.26e-1)" "unprognostic (1.46e-2)" "unprognostic (6.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.00e-1)" "unprognostic (1.38e-3)" "unprognostic (4.40e-2)" "unprognostic (1.24e-1)" "unprognostic (2.54e-2)" "unprognostic (2.21e-1)" "unprognostic (4.85e-2)" "unprognostic (5.13e-1)" "unprognostic (2.70e-1)" "unprognostic (4.61e-2)" MASP1 "CRARF, MAP-1, Map44, MASP, MASP-3, PRSS5" ENSG00000127241 "MBL associated serine protease 1" P48740 3 187217282-187291980 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement activation lectin pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 100.9;heart muscle: 108.6;liver: 171.6" "Cell type enhanced" "Detected in some" "Astrocytes: 61.5;Bergmann glia: 25.8;Cardiomyocytes: 60.7;Cholangiocytes: 40.1;Decidual stromal cells: 82.8;Endometrial stromal cells: 43.6;Ependymal cells: 42.5;Epididymal efferent duct absorptive cells: 28.1;Epididymal efferent duct ciliated cells: 25.6;Fibro-adipogenic progenitors: 53.1;Hepatic stellate cells: 90.4;Hepatocytes: 108.9;Oligodendrocyte progenitor cells: 37.3" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 53.1;Glial cells: 61.5;Hepatocytes: 108.9;Myocytes: 60.7;Stellate cells: 90.4;Stromal cells: 82.8" "Cell type enhanced" "Detected in many" "astrocyte: 114.5;ependymal cell: 51.3;oligodendrocyte precursor cell: 42.0" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 40.6;Kidney Renal Clear Cell Carcinoma (TCGA): 20.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 22.8;Liver Hepatocellular Carcinoma (TCGA): 28.4;Prostate Adenocarcinoma (TCGA): 14.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 11.8;Rhabdoid: 14.6" "Adipose visceral - Mast cells, Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Pancreas - Fibroblasts, Prostate - Smooth muscle cells, Skin - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 157 "Hepatocytes: 15716.5" "Tissue enhanced" "Detected in many" "heart muscle: 28969996.7" "HPA001617, HPA009641" Supported Enhanced Nucleoplasm,Cytosol "Secreted to blood" Immunity No NA 8670000000 2200000000 "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Nucleoplasm, Cytosol" "HPA001617: , HPA009641: " "unprognostic (6.70e-2)" "unprognostic (1.13e-3)" "unprognostic (1.17e-1)" "unprognostic (1.20e-1)" "unprognostic (4.39e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (8.75e-6)" "unprognostic (1.49e-2)" "validated prognostic favorable (2.10e-6)" "validated prognostic favorable (2.18e-4)" "unprognostic (2.97e-1)" "unprognostic (1.08e-3)" "potential prognostic favorable (2.16e-4)" "unprognostic (5.65e-3)" "unprognostic (1.67e-1)" "unprognostic (1.27e-1)" "unprognostic (2.15e-1)" "unprognostic (4.35e-1)" "unprognostic (5.26e-2)" "unprognostic (2.32e-1)" "unprognostic (1.33e-1)" "unprognostic (9.69e-2)" "unprognostic (6.74e-2)" "unprognostic (5.01e-2)" MAST1 "KIAA0973, SAST" ENSG00000105613 "Microtubule associated serine/threonine kinase 1" Q9Y2H9 19 12833951-12874952 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 92.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 103.4;Brain inhibitory neurons: 75.7;Cone photoreceptor cells: 101.4;Early spermatids: 44.9;Lactotrophs: 62.9;Late spermatids: 62.8;Other brain neurons: 107.5;Retinal amacrine cells: 150.4;Retinal bipolar cells: 87.8;Retinal ganglion cells: 193.1;Retinal horizontal cells: 84.1;Rod photoreceptor cells: 75.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 42.5;Neuronal cells: 193.1;Pituitary endocrine cells: 62.9;Spermatogenic cell types: 62.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 52772 "Astrocytes and Neuropil: 3817399.3;Microglia and Neuropil: 6610845.2;Neurons: 5403433.6" "Tissue enriched" "Detected in single" 51335 "cerebral cortex: 5133527.1" "HPA028181, HPA073106" Enhanced Supported Vesicles,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 17 Vesicles Cytosol "HPA028181: , HPA073106: " "unprognostic (1.36e-1)" "unprognostic (1.63e-2)" "unprognostic (1.14e-1)" "unprognostic (1.08e-3)" "unprognostic (8.50e-2)" "potential prognostic favorable (2.75e-4)" "unprognostic (2.79e-3)" "unprognostic (1.04e-2)" "unprognostic (3.57e-1)" "unprognostic (2.96e-1)" "unprognostic (4.33e-3)" "unprognostic (8.78e-3)" "unprognostic (2.44e-1)" "unprognostic (6.94e-3)" MAST3 KIAA0561 ENSG00000099308 "Microtubule associated serine/threonine kinase 3" O60307 19 18097778-18151692 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 44.9" "Cell type enriched" "Detected in many" 4 "Neutrophils: 378.5" "Cell type enriched" "Detected in many" 4 "Neutrophils: 378.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 11912524.9;Pancreas epithelial cells: 11537062.0" "Group enriched" "Detected in many" "cerebral cortex: 1130542.1;lung: 3970222.5;pancreas: 1034085.0" "HPA035061, HPA035062" Uncertain Approved "Nuclear speckles" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 13 "Nuclear speckles" "HPA035061: , HPA035062: " "unprognostic (6.90e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (9.90e-4)" "unprognostic (2.96e-1)" "unprognostic (7.37e-2)" "unprognostic (5.58e-2)" "unprognostic (6.03e-2)" "unprognostic (2.06e-1)" "potential prognostic favorable (8.09e-4)" "unprognostic (1.01e-2)" "unprognostic (1.85e-1)" "unprognostic (6.13e-3)" "unprognostic (2.46e-1)" "unprognostic (2.07e-1)" "unprognostic (1.55e-2)" "unprognostic (1.32e-2)" "unprognostic (4.88e-2)" "unprognostic (9.59e-2)" "unprognostic (1.09e-2)" "unprognostic (9.87e-2)" "unprognostic (1.58e-2)" "unprognostic (1.48e-3)" "unprognostic (5.63e-2)" "unprognostic (3.12e-1)" "unprognostic (1.80e-2)" "unprognostic (7.55e-2)" "unprognostic (3.25e-1)" "unprognostic (1.21e-2)" "unprognostic (2.76e-1)" "unprognostic (1.61e-2)" "unprognostic (2.58e-1)" MATCAP2 KIAA0895 ENSG00000164542 "Microtubule associated tyrosine carboxypeptidase 2" Q8NCT3 7 36324152-36390125 "Predicted intracellular proteins" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 20.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 101.4;Early spermatids: 121.8;Endometrial ciliated cells: 107.3;Gastric chief cells: 104.8;Late spermatids: 108.2;Parietal cells: 100.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 107.3;Gastric glandular cells: 104.8;Neuronal cells: 101.4;Spermatogenic cell types: 121.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 1616 "skin: 161562.3" "HPA021036, HPA061066" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 67: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" Nucleoplasm "Plasma membrane, Cell Junctions, Cytosol" "HPA021036: , HPA061066: " "unprognostic (4.08e-2)" "unprognostic (2.21e-2)" "unprognostic (1.53e-1)" "unprognostic (9.78e-2)" "unprognostic (2.81e-1)" "unprognostic (6.01e-2)" "unprognostic (5.20e-2)" "potential prognostic unfavorable (6.89e-4)" "unprognostic (1.58e-2)" "unprognostic (8.63e-2)" "potential prognostic favorable (9.73e-6)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "unprognostic (7.36e-3)" "potential prognostic unfavorable (8.22e-4)" "unprognostic (2.08e-2)" "unprognostic (9.71e-2)" "unprognostic (2.07e-1)" "unprognostic (4.30e-2)" "unprognostic (2.56e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.51e-2)" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (3.04e-1)" "unprognostic (1.16e-2)" "unprognostic (1.02e-2)" "unprognostic (1.51e-2)" "unprognostic (3.60e-3)" MATK "CHK, CTK, DKFZp434N1212, HHYLTK, HYL, HYLTK, Lsk, MGC1708, MGC2101" ENSG00000007264 "Megakaryocyte-associated tyrosine kinase" P42679 19 3777970-3802129 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 19.3;brain: 55.6" "Group enriched" "Detected in many" 5 "NK-cells: 179.7;Tuft cells: 495.7" "Group enriched" "Detected in many" 5 "NK-cells: 179.7;Secretory gland support: 495.7" "Cell type enhanced" "Detected in many" "leukocyte: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 77.1" "Group enriched" "Detected in many" 57 "NK-cells: 77.1;T-cells: 46.3" "Cancer enhanced" "Detected in many" "Leukemia: 56.3" "Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Large ducts: 398676.1;T-cells: 434480.4" "Group enriched" "Detected in some" 45758 "cerebral cortex: 5042114.7;lymphoid tissue: 4109432.8" "HPA004847, HPA066547" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 11 Microtubules "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Cytosol" "HPA004847: , HPA066547: " "unprognostic (2.28e-1)" "potential prognostic favorable (3.81e-4)" "unprognostic (1.49e-2)" "unprognostic (7.38e-3)" "unprognostic (2.35e-1)" "unprognostic (2.45e-1)" "unprognostic (8.35e-2)" "unprognostic (2.44e-1)" "unprognostic (3.62e-2)" "unprognostic (1.82e-1)" "unprognostic (5.78e-3)" "unprognostic (2.65e-2)" "unprognostic (1.66e-1)" "unprognostic (1.83e-2)" "unprognostic (3.70e-2)" "unprognostic (2.16e-2)" "unprognostic (9.24e-2)" "unprognostic (7.10e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (9.35e-2)" "unprognostic (2.07e-2)" "unprognostic (7.23e-2)" "unprognostic (3.47e-2)" "unprognostic (9.41e-2)" "unprognostic (7.92e-2)" "unprognostic (1.83e-1)" "unprognostic (5.83e-2)" "unprognostic (2.20e-1)" "unprognostic (1.21e-1)" "unprognostic (1.79e-1)" MBD5 "FLJ11113, KIAA1461" ENSG00000204406 "Methyl-CpG binding domain protein 5" Q9P267 2 148021011-148516971 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2334 "Neurons: 206485.4;Pancreatic islets: 260348.4" "Tissue enriched" "Detected in single" 3963 "intestine: 396300.2" HPA035964 Supported Nucleoplasm,Midbody Yes NA "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 4 Nucleoplasm Midbody "HPA035964: " "unprognostic (9.06e-2)" "unprognostic (3.20e-2)" "unprognostic (1.65e-1)" "unprognostic (2.33e-2)" "unprognostic (1.86e-1)" "unprognostic (1.11e-1)" "unprognostic (9.43e-2)" "unprognostic (6.25e-2)" "unprognostic (3.21e-2)" "unprognostic (2.08e-1)" "potential prognostic favorable (6.39e-4)" "unprognostic (1.49e-3)" "unprognostic (4.50e-3)" "unprognostic (4.10e-1)" "unprognostic (3.34e-1)" "unprognostic (2.31e-1)" "unprognostic (9.01e-2)" "unprognostic (5.29e-2)" "unprognostic (1.48e-1)" "unprognostic (1.49e-3)" "unprognostic (9.64e-2)" "unprognostic (4.67e-3)" "unprognostic (7.23e-2)" "unprognostic (3.18e-1)" "unprognostic (1.05e-2)" "unprognostic (7.61e-2)" "unprognostic (1.44e-1)" "unprognostic (5.07e-2)" "unprognostic (2.58e-2)" "unprognostic (2.86e-1)" MBLAC2 "DKFZp686P15118, MGC46734" ENSG00000176055 "Metallo-beta-lactamase domain containing 2" Q68D91 5 90458209-90474771 "Enzymes, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.3;Corticotrophs: 29.1" "Cell type enhanced" "Detected in many" "Neuronal cells: 39.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 12608173.7" "Tissue enriched" "Detected in all" "cerebral cortex: 60984951.7" "HPA037757, HPA037758" Uncertain Approved Nucleoplasm,Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 3 Mitochondria Nucleoplasm "HPA037757: , HPA037758: " "unprognostic (8.12e-2)" "unprognostic (1.09e-1)" "unprognostic (2.00e-1)" "unprognostic (1.57e-1)" "unprognostic (2.85e-1)" "unprognostic (1.95e-1)" "unprognostic (1.56e-1)" "unprognostic (2.65e-1)" "unprognostic (9.55e-3)" "unprognostic (5.71e-3)" "potential prognostic favorable (6.77e-8)" "unprognostic (1.11e-1)" "unprognostic (5.96e-2)" "unprognostic (2.78e-2)" "unprognostic (4.51e-2)" "unprognostic (1.50e-1)" "unprognostic (3.28e-1)" "unprognostic (2.46e-1)" "unprognostic (4.33e-3)" "unprognostic (6.40e-2)" "unprognostic (3.87e-2)" "unprognostic (2.74e-1)" "unprognostic (1.01e-3)" "unprognostic (5.72e-2)" "unprognostic (3.81e-2)" "unprognostic (4.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.09e-1)" "unprognostic (1.49e-1)" MBOAT2 "FLJ14415, FLJ90298, LPLAT13, OACT2" ENSG00000143797 "Membrane bound O-acyltransferase domain containing 2" Q6ZWT7 2 8852690-9003709 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 486.0;Choroid plexus epithelial cells: 441.6;Conjunctival goblet cells: 412.6;Erythrocyte progenitors: 618.9;Esophageal apical cells: 1372.2;Esophageal suprabasal cells: 523.1;Neutrophil progenitors: 666.9;Neutrophils: 645.1;Retinal horizontal cells: 418.7;Salivary duct cells: 712.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 1372.2;Ductal cells: 712.9;Neutrophils: 666.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 4.7;eosinophil: 1.7;neutrophil: 4.0" "Lineage enriched" "Detected in single" 10 "granulocytes: 4.7" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Prostate glandular cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 8258993.8" "Group enriched" "Detected in some" "bone marrow: 957168.4;cerebral cortex: 2392055.4;lung: 1931848.8;lymphoid tissue: 1365394.0" HPA014836 Uncertain Approved Vesicles NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Vesicles "HPA014836: " "unprognostic (3.08e-3)" "unprognostic (4.37e-1)" "unprognostic (9.44e-2)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (2.10e-1)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (2.39e-1)" "unprognostic (4.22e-2)" "unprognostic (5.41e-2)" "unprognostic (9.81e-2)" "unprognostic (4.96e-3)" "unprognostic (1.66e-2)" "unprognostic (3.60e-1)" "unprognostic (2.82e-3)" "unprognostic (2.17e-3)" "potential prognostic unfavorable (2.29e-5)" "unprognostic (4.73e-2)" "unprognostic (1.17e-1)" "unprognostic (3.40e-1)" "unprognostic (4.77e-3)" "unprognostic (7.52e-3)" "unprognostic (1.78e-2)" "unprognostic (3.88e-1)" "unprognostic (1.28e-1)" "unprognostic (4.76e-2)" "unprognostic (2.57e-1)" "unprognostic (1.68e-1)" "unprognostic (1.64e-1)" "unprognostic (1.51e-1)" "unprognostic (5.49e-3)" MCCC2 "MCCB, MCCCbeta" ENSG00000131844 "Methylcrotonyl-CoA carboxylase subunit 2" Q9HCC0 5 71579531-71658706 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 109.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 184.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA038300, HPA038301, HPA061546" Enhanced Enhanced Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 60: Prostate cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 14 Mitochondria "HPA038300: , HPA038301: , HPA061546: " "unprognostic (6.22e-2)" "unprognostic (1.04e-1)" "unprognostic (2.39e-1)" "unprognostic (5.48e-2)" "unprognostic (3.24e-2)" "unprognostic (4.61e-3)" "unprognostic (4.34e-2)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (3.31e-4)" "potential prognostic favorable (2.19e-7)" "unprognostic (5.56e-2)" "unprognostic (4.34e-3)" "unprognostic (2.40e-3)" "unprognostic (2.31e-2)" "unprognostic (2.39e-3)" "unprognostic (3.14e-1)" "unprognostic (3.51e-1)" "unprognostic (1.43e-2)" "unprognostic (8.06e-2)" "unprognostic (6.70e-2)" "unprognostic (2.54e-1)" "unprognostic (1.99e-1)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "unprognostic (7.71e-2)" "unprognostic (2.28e-1)" "unprognostic (6.09e-2)" "unprognostic (3.09e-1)" "unprognostic (3.28e-2)" "unprognostic (8.79e-2)" MCEE "GLOD2, MCE, MMCE" ENSG00000124370 "Methylmalonyl-CoA epimerase" Q96PE7 2 71109684-71130239 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 181.2;Myonuclei: 164.2" "Cell type enhanced" "Detected in many" "Secretory cells: 181.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "heart muscle: 93371975.2" HPA035196 Approved Nucleoli No No 15000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Myocytes - Oxidative muscle function" 6 Nucleoli "HPA035196: " "unprognostic (4.36e-2)" "unprognostic (1.20e-3)" "unprognostic (6.46e-2)" "unprognostic (1.78e-1)" "unprognostic (4.95e-2)" "unprognostic (4.13e-2)" "unprognostic (2.97e-1)" "unprognostic (1.10e-1)" "unprognostic (6.55e-3)" "unprognostic (6.28e-3)" "potential prognostic favorable (2.07e-5)" "unprognostic (2.00e-2)" "unprognostic (2.23e-2)" "potential prognostic favorable (2.50e-5)" "unprognostic (4.33e-2)" "unprognostic (3.76e-1)" "unprognostic (4.63e-2)" "unprognostic (2.16e-2)" "unprognostic (3.48e-1)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (7.17e-3)" "unprognostic (9.95e-2)" "unprognostic (2.63e-1)" "unprognostic (2.00e-1)" "unprognostic (2.46e-2)" "unprognostic (7.54e-2)" "unprognostic (2.81e-1)" "unprognostic (9.81e-2)" "unprognostic (1.61e-1)" "unprognostic (1.17e-1)" MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7677088-7679829 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 77.3;lung: 82.9;lymphoid tissue: 49.5" "Cell type enriched" "Detected in some" 4 "Neutrophils: 82.5" "Cell type enriched" "Detected in some" 7 "Neutrophils: 82.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 10.2" "Group enriched" "Detected in some" 5 "cerebral cortex: 6.2;pons: 2.8;thalamus: 2.9" "Group enriched" "Detected in many" 5 "classical monocyte: 124.0;neutrophil: 57.5" "Group enriched" "Detected in many" 5 "granulocytes: 57.5;monocytes: 124.0" "Cancer enriched" "Detected in some" 6 "Leukemia: 17.5" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Kidney - Macrophages, Liver - Neutrophils, Pituitary gland - Neutrophils, Prostate - Macrophages, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Neutrophils: 26203287.3" "Group enriched" "Detected in some" "bone marrow: 5770617.8;lung: 2257910.5" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 9 "Plasma membrane" "HPA014731: " "unprognostic (2.73e-1)" "unprognostic (2.53e-1)" "potential prognostic unfavorable (5.33e-4)" "unprognostic (4.41e-3)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (2.08e-5)" "unprognostic (3.08e-2)" "unprognostic (1.76e-2)" "unprognostic (2.22e-2)" "unprognostic (8.57e-3)" "unprognostic (1.12e-1)" "unprognostic (2.05e-3)" "unprognostic (1.63e-2)" MCL1 "BCL2L3, Mcl-1" ENSG00000143384 "MCL1 apoptosis regulator, BCL2 family member" Q07820 1 150560895-150579738 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 646.6" "Cell type enhanced" "Detected in many" "monocytes: 1779.3;Neutrophils: 5897.5" "Cell type enhanced" "Detected in many" "Neutrophils: 5897.5" "Cell type enhanced" "Detected in all" "endothelial cell: 125.3;leukocyte: 128.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 106.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 33303.1;B-cells: 30463.3;Hepatocytes: 34086.5;Macrophages: 100467.0;T-cells: 113571.3" "Group enriched" "Detected in some" "liver: 140930.8;lung: 287259.9;lymphoid tissue: 261425.7" "CAB002781, HPA008455, HPA031125, CAB068195" Enhanced Enhanced Mitochondria Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 63 Mitochondria "CAB002781: , CAB068195: , HPA008455: , HPA031125: " "unprognostic (2.71e-2)" "unprognostic (3.47e-1)" "unprognostic (6.85e-3)" "unprognostic (5.89e-3)" "unprognostic (4.59e-2)" "unprognostic (2.80e-2)" "unprognostic (2.62e-1)" "unprognostic (2.40e-1)" "unprognostic (2.79e-2)" "unprognostic (4.12e-1)" "potential prognostic favorable (6.96e-4)" "unprognostic (1.74e-2)" "unprognostic (2.68e-2)" "unprognostic (1.31e-2)" "unprognostic (2.81e-2)" "unprognostic (1.75e-2)" "unprognostic (4.14e-2)" "unprognostic (2.37e-2)" "unprognostic (2.09e-1)" "unprognostic (2.87e-3)" "unprognostic (7.62e-2)" "unprognostic (1.06e-2)" "unprognostic (1.16e-2)" "unprognostic (8.05e-2)" "unprognostic (3.92e-1)" "unprognostic (2.35e-2)" "unprognostic (1.05e-1)" "unprognostic (5.04e-2)" "unprognostic (2.89e-1)" "unprognostic (7.09e-2)" "unprognostic (1.26e-1)" MCM10 "CNA43, DNA43, PRO2249" ENSG00000065328 "Minichromosome maintenance 10 replication initiation factor" Q7L590 10 13161558-13211110 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA replication" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;lymphoid tissue: 7.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 17.2;Differentiating spermatogonia: 16.4;Early primary spermatocytes: 32.1;Erythrocyte progenitors: 96.8;Extravillous trophoblasts: 28.4;Megakaryocyte progenitors: 62.8;Megakaryocytes: 18.5;Migrating cytotrophoblasts: 27.3;Monocyte progenitors: 47.7;Neutrophil progenitors: 22.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 96.8;Megakaryocytes: 62.8;Mononuclear phagocytes: 47.7;Spermatogenic cell types: 32.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pituitary gland - Thyrotropes, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 28124 "Glomeruli: 1640315.8;Oocytes: 3984500.7" "Not detected" "Not detected" "HPA045899, HPA071952" Approved Supported Nucleoplasm,Nucleoli Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 31 "Nucleoplasm, Nucleoli" "HPA045899: , HPA071952: " "unprognostic (2.08e-3)" "unprognostic (2.73e-2)" "unprognostic (2.08e-1)" "unprognostic (5.97e-2)" "unprognostic (1.70e-1)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "potential prognostic favorable (3.76e-4)" "unprognostic (1.56e-2)" "unprognostic (1.88e-3)" "validated prognostic unfavorable (8.32e-9)" "validated prognostic unfavorable (4.21e-8)" "validated prognostic unfavorable (3.72e-5)" "validated prognostic unfavorable (3.15e-4)" "unprognostic (1.68e-1)" "unprognostic (1.52e-2)" "unprognostic (4.38e-2)" "unprognostic (1.94e-1)" "validated prognostic unfavorable (5.15e-4)" "validated prognostic unfavorable (1.11e-4)" "unprognostic (1.05e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-2)" "unprognostic (6.80e-2)" "unprognostic (1.61e-1)" "unprognostic (2.17e-1)" MCM2 "BM28, CCNL1, cdc19, CDCL1, D3S3194, DFNA70, KIAA0030" ENSG00000073111 "Minichromosome maintenance complex component 2" P49736 3 127598410-127622436 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 63.9;lymphoid tissue: 35.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 77.1;Differentiating spermatogonia: 37.8;Erythrocyte progenitors: 121.7;Extravillous trophoblasts: 28.4;Megakaryocyte progenitors: 62.7;Megakaryocyte-Erythroid progenitors: 38.4;Migrating cytotrophoblasts: 58.6;Monocyte progenitors: 44.2;Neutrophil progenitors: 30.1;Platelets: 28.2;Syncytiotrophoblasts: 30.4" "Cell type enhanced" "Detected in many" "Erythrocytes: 121.7;Megakaryocytes: 62.7;Trophoblast cells: 77.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "Granulosa cells: 96849840.2;Neutrophils: 30006882.3;Oocytes: 31169646.2" "Tissue enriched" "Detected in many" "bone marrow: 52663238.9" "CAB000303, HPA031450, HPA031495, HPA031496" Enhanced Supported "Nucleoplasm,Vesicles,Primary cilium,Cytosol" Yes Yes 160000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 227 Nucleoplasm "Vesicles, Primary cilium, Cytosol" "CAB000303: , HPA031450: , HPA031495: , HPA031496: " "unprognostic (1.64e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (5.08e-2)" "unprognostic (4.13e-1)" "unprognostic (1.88e-1)" "unprognostic (2.18e-1)" "unprognostic (3.68e-1)" "unprognostic (5.12e-2)" "unprognostic (8.23e-3)" "unprognostic (5.57e-2)" "unprognostic (6.29e-3)" "unprognostic (5.65e-3)" "validated prognostic unfavorable (1.10e-6)" "validated prognostic unfavorable (8.17e-8)" "unprognostic (1.54e-3)" "unprognostic (2.22e-3)" "unprognostic (3.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.84e-1)" "unprognostic (1.84e-1)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (4.09e-2)" "unprognostic (5.96e-3)" "unprognostic (2.65e-2)" "unprognostic (2.34e-2)" "unprognostic (1.64e-2)" "unprognostic (3.06e-2)" "unprognostic (8.52e-2)" "unprognostic (7.68e-2)" "unprognostic (4.10e-1)" MCM3 ENSG00000112118 "Minichromosome maintenance complex component 3" P25205 6 52264014-52284881 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 155.9;Erythrocyte progenitors: 221.2;Megakaryocyte progenitors: 175.8;Megakaryocyte-Erythroid progenitors: 105.9;Migrating cytotrophoblasts: 124.1;Monocyte progenitors: 99.9;Oocytes: 105.9" "Cell type enhanced" "Detected in all" "Erythrocytes: 221.2;Megakaryocytes: 175.8;Trophoblast cells: 155.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 87021718.4;Neutrophils: 52774055.2;Oocytes: 118912819.6" "Tissue enhanced" "Detected in many" "bone marrow: 188248171.2" "CAB002162, HPA004789, HPA004790" Supported Approved Nucleoplasm NA Yes 52000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 76 Nucleoplasm "CAB002162: , HPA004789: , HPA004790: " "unprognostic (4.63e-1)" "unprognostic (4.31e-2)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (2.07e-1)" "unprognostic (2.01e-1)" "unprognostic (2.88e-1)" "unprognostic (5.15e-2)" "unprognostic (4.11e-2)" "unprognostic (1.20e-3)" "unprognostic (2.57e-3)" "unprognostic (9.29e-2)" "unprognostic (1.19e-1)" "validated prognostic unfavorable (4.66e-5)" "validated prognostic unfavorable (8.22e-6)" "unprognostic (8.17e-3)" "unprognostic (2.11e-3)" "unprognostic (6.00e-2)" "unprognostic (2.34e-2)" "unprognostic (1.88e-3)" "unprognostic (1.04e-2)" "unprognostic (3.37e-2)" "unprognostic (2.05e-2)" "unprognostic (1.93e-1)" "unprognostic (1.10e-1)" "unprognostic (3.58e-2)" "potential prognostic unfavorable (9.02e-4)" "unprognostic (2.25e-2)" "unprognostic (2.40e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-1)" MCM4 "CDC21, CDC54, hCdc21, MGC33310, P1-Cdc21" ENSG00000104738 "Minichromosome maintenance complex component 4" P33991 8 47960185-47978160 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 52.0" "Cell type enhanced" "Detected in many" "Early spermatids: 160.3;Erythrocyte progenitors: 288.2;Late primary spermatocytes: 147.1;Late spermatids: 110.6;Megakaryocyte progenitors: 134.0;Monocyte progenitors: 123.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 288.2;Megakaryocytes: 134.0;Mononuclear phagocytes: 123.6;Spermatogenic cell types: 160.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 59899345.6;Neutrophils: 47519810.5;Oocytes: 25289949.2" "Tissue enriched" "Detected in many" "bone marrow: 55638085.7" "CAB004497, HPA004873, HPA031052" Enhanced Enhanced Nucleoplasm NA Yes 85000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 90 Nucleoplasm "CAB004497: , HPA004873: , HPA031052: " "unprognostic (7.68e-2)" "unprognostic (4.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.09e-2)" "unprognostic (4.67e-2)" "unprognostic (3.64e-1)" "unprognostic (7.39e-2)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (9.02e-5)" "unprognostic (3.65e-3)" "unprognostic (1.29e-3)" "unprognostic (4.88e-3)" "validated prognostic unfavorable (2.36e-5)" "validated prognostic unfavorable (5.39e-5)" "validated prognostic unfavorable (1.65e-4)" "validated prognostic unfavorable (6.35e-5)" "unprognostic (1.58e-2)" "unprognostic (1.55e-1)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (5.63e-2)" "unprognostic (1.68e-2)" "unprognostic (4.44e-2)" "unprognostic (1.72e-2)" "unprognostic (1.65e-2)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "unprognostic (4.27e-2)" "unprognostic (2.26e-1)" MCM5 CDC46 ENSG00000100297 "Minichromosome maintenance complex component 5" P33992 22 35400134-35425431 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 130.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 178.9;Differentiating spermatogonia: 91.9;Erythrocyte progenitors: 183.2;Extravillous trophoblasts: 81.7;Megakaryocyte progenitors: 89.9;Migrating cytotrophoblasts: 147.3;Monocyte progenitors: 89.8;Oocytes: 133.5;Syncytiotrophoblasts: 79.5" "Cell type enhanced" "Detected in all" "Erythrocytes: 183.2;Oocytes: 133.5;Trophoblast cells: 178.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 22.8;leukocyte: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 52403874.8;Neutrophils: 31616271.9;Oocytes: 125054202.8" "Tissue enhanced" "Detected in many" "bone marrow: 257242968.5" "CAB000101, HPA000845, HPA052880" Enhanced Enhanced Nucleoplasm Yes Yes 68000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 76 Nucleoplasm "CAB000101: , HPA000845: , HPA052880: " "unprognostic (1.43e-1)" "unprognostic (4.79e-2)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" "unprognostic (8.39e-2)" "unprognostic (3.11e-1)" "unprognostic (3.70e-1)" "unprognostic (3.15e-3)" "unprognostic (1.21e-2)" "unprognostic (5.79e-3)" "unprognostic (3.97e-3)" "unprognostic (1.82e-1)" "unprognostic (4.30e-2)" "validated prognostic unfavorable (4.86e-5)" "validated prognostic unfavorable (4.47e-7)" "potential prognostic unfavorable (4.15e-7)" "unprognostic (5.09e-2)" "unprognostic (1.63e-2)" "unprognostic (1.07e-2)" "unprognostic (1.20e-1)" "unprognostic (2.88e-2)" "unprognostic (9.34e-3)" "unprognostic (3.96e-2)" "unprognostic (3.91e-2)" "unprognostic (1.21e-2)" "unprognostic (5.05e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-2)" "unprognostic (3.10e-1)" "unprognostic (2.56e-2)" "unprognostic (1.91e-1)" MCM6 Mis5 ENSG00000076003 "Minichromosome maintenance complex component 6" Q14566 2 135839626-135876443 "Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication" "DNA-binding, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 45.2" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 171.2;Megakaryocyte progenitors: 112.6;Megakaryocyte-Erythroid progenitors: 62.8;Monocyte progenitors: 94.8;Neutrophil progenitors: 58.3" "Cell type enhanced" "Detected in many" "Erythrocytes: 171.2;Megakaryocytes: 112.6;Mononuclear phagocytes: 94.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 82411285.1;Neutrophils: 46808529.3;Oocytes: 22430750.2" "Group enriched" "Detected in many" "bone marrow: 67492388.7;intestine: 22721529.6" "HPA004818, CAB009577" Enhanced Supported Nucleoplasm NA Yes 180000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 35: Non-specific - DNA binding" "Cluster 58: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 101 Nucleoplasm "CAB009577: , HPA004818: " "unprognostic (2.07e-1)" "unprognostic (1.26e-1)" "unprognostic (1.81e-1)" "unprognostic (2.73e-2)" "unprognostic (8.32e-2)" "unprognostic (1.75e-1)" "unprognostic (1.24e-1)" "unprognostic (2.08e-1)" "unprognostic (5.45e-2)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (3.61e-3)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.30e-7)" "validated prognostic unfavorable (1.03e-6)" "validated prognostic unfavorable (6.26e-8)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (2.54e-2)" "unprognostic (6.26e-2)" "unprognostic (5.69e-2)" "unprognostic (2.24e-1)" "unprognostic (2.10e-2)" "unprognostic (3.24e-2)" "unprognostic (6.46e-2)" "unprognostic (1.74e-3)" "unprognostic (9.69e-2)" "unprognostic (1.40e-3)" "unprognostic (8.94e-2)" "unprognostic (7.37e-2)" "unprognostic (4.99e-2)" "unprognostic (1.86e-1)" MCM8 "C20orf154, dJ967N21.5, MGC119522, MGC119523, MGC12866, MGC4816, REC" ENSG00000125885 "Minichromosome maintenance 8 homologous recombination repair factor" Q9UJA3 20 5950652-5998977 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 12.6;Distal convoluted tubule cells: 13.0;Early primary spermatocytes: 8.9;Ependymal cells: 8.2;Erythrocyte progenitors: 8.5;Loop of henle epithelial cells: 19.1;Microglia: 7.7;Oligodendrocytes: 9.9;Papillary tip epithelial cells: 8.8;Podocytes: 7.5;Proximal tubule cells: 14.5;Renal collecting duct intercalated cells: 14.5;Renal collecting duct principal cells: 15.3;Renal connecting tubule cells: 12.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 12.6;Ductal cells: 15.3;Glial cells: 9.9;Renal nephron cells: 19.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 93 "Granulosa cells: 9289.4" "Tissue enriched" "Detected in some" "skeletal muscle: 379944.1" "HPA045141, HPA066433" Supported Nucleoplasm,Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 102: Non-specific - Mixed function" 16 Nucleoplasm Cytosol "HPA045141: , HPA066433: " "unprognostic (1.70e-3)" "unprognostic (1.10e-1)" "unprognostic (8.67e-2)" "unprognostic (1.39e-1)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (3.27e-1)" "unprognostic (7.37e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-2)" "unprognostic (3.09e-2)" "unprognostic (7.91e-3)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.00e-6)" "unprognostic (1.97e-3)" "validated prognostic unfavorable (8.10e-4)" "validated prognostic unfavorable (9.62e-4)" "unprognostic (1.30e-2)" "unprognostic (5.61e-2)" "unprognostic (2.17e-1)" "unprognostic (3.53e-1)" "unprognostic (1.64e-3)" "unprognostic (8.72e-3)" "unprognostic (8.49e-2)" "unprognostic (3.89e-2)" "unprognostic (3.05e-2)" "unprognostic (2.68e-2)" "unprognostic (8.60e-2)" "unprognostic (1.52e-1)" "unprognostic (2.35e-3)" "unprognostic (3.49e-2)" MCOLN1 "ML4, MLIV, MST080, MSTP080, TRPM-L1, TRPML1" ENSG00000090674 "Mucolipin TRP cation channel 1" Q9GZU1 19 7522624-7534009 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Calcium transport, Immunity, Ion transport, Transport" "Ion channel" "Corneal dystrophy, Disease variant, Mucolipidosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 84.9;Hofbauer cells: 111.6;Kupffer cells: 136.3;Macrophages: 67.5;Neutrophils: 74.0" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 136.3;Pituitary endocrine cells: 84.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 118.2;classical monocyte: 45.3;eosinophil: 106.1;intermediate monocyte: 95.7;neutrophil: 41.4;non-classical monocyte: 105.7" "Group enriched" "Detected in all" 5 "granulocytes: 118.2;monocytes: 105.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Prostate - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 5130290.5" "Tissue enhanced" "Detected in some" "bone marrow: 16129.0;lymphoid tissue: 11028.2" "HPA031763, CAB032637" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 5: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 7 "Plasma membrane" Cytosol "CAB032637: , HPA031763: " "unprognostic (8.33e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.74e-3)" "unprognostic (1.18e-1)" "unprognostic (6.11e-2)" "unprognostic (1.65e-1)" "unprognostic (6.66e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (4.86e-4)" "potential prognostic favorable (1.04e-6)" "unprognostic (1.65e-1)" "unprognostic (6.02e-2)" "unprognostic (1.85e-2)" "unprognostic (2.23e-2)" "unprognostic (1.84e-1)" "unprognostic (8.75e-2)" "unprognostic (1.59e-1)" "unprognostic (1.46e-1)" "unprognostic (3.87e-1)" "unprognostic (1.43e-1)" "potential prognostic favorable (4.11e-4)" "unprognostic (1.02e-1)" "unprognostic (3.06e-1)" "unprognostic (2.86e-3)" "unprognostic (1.07e-2)" "unprognostic (2.77e-1)" "unprognostic (2.78e-1)" "unprognostic (2.68e-2)" "unprognostic (1.44e-1)" "unprognostic (1.24e-1)" MCU "C10orf42, CCDC109A, FLJ46135" ENSG00000156026 "Mitochondrial calcium uniporter" Q8NE86 10 72692143-72887694 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 51.2" "Cell type enhanced" "Detected in many" "Foveolar cells: 945.3;Myonuclei: 1130.9;Neutrophil progenitors: 1471.2" "Cell type enhanced" "Detected in all" "Myocytes: 1130.9;Neutrophils: 1471.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Stomach - Gastric mucous cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 34204802.0" "Low tissue specificity" "Detected in all" HPA016480 Approved Supported Mitochondria No No 37000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 15 Mitochondria "HPA016480: " "unprognostic (1.81e-2)" "unprognostic (4.86e-2)" "unprognostic (1.15e-1)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (3.53e-1)" "potential prognostic favorable (1.65e-5)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (9.86e-4)" "potential prognostic favorable (1.99e-7)" "unprognostic (7.06e-2)" "unprognostic (4.12e-1)" "unprognostic (3.17e-2)" "unprognostic (3.32e-2)" "unprognostic (6.42e-2)" "unprognostic (2.66e-1)" "unprognostic (9.85e-3)" "unprognostic (8.80e-2)" "unprognostic (2.45e-2)" "unprognostic (1.14e-1)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (1.42e-1)" "unprognostic (4.74e-3)" "unprognostic (1.35e-2)" "unprognostic (2.84e-2)" "unprognostic (7.80e-2)" "unprognostic (3.97e-1)" "unprognostic (1.77e-1)" "unprognostic (3.26e-2)" MDC1 "Em:AB023051.5, KIAA0170, NFBD1" ENSG00000137337 "Mediator of DNA damage checkpoint 1" Q14676 6 30699807-30717447 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.3;Bergmann glia: 19.8;Distal convoluted tubule cells: 15.7;Ependymal cells: 13.0;Loop of henle epithelial cells: 21.8;Microglia: 13.6;Oligodendrocyte progenitor cells: 17.9;Oligodendrocytes: 13.9;Podocytes: 15.7;Proximal tubule cells: 19.9;Renal collecting duct intercalated cells: 19.5;Renal collecting duct principal cells: 19.8;Renal connecting tubule cells: 19.2;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "Ductal cells: 19.8;Glial cells: 19.8;Renal nephron cells: 21.8;Secretory gland support: 23.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 4 "NK-cells: 3.2" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 12484430.6" "Group enriched" "Detected in many" "intestine: 4306528.0;skin: 5068814.8" "HPA006915, CAB080094, CAB080116" Enhanced Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 87 "Nucleoplasm, Nuclear bodies" "CAB080094: , CAB080116: , HPA006915: " "unprognostic (1.67e-1)" "unprognostic (1.32e-1)" "unprognostic (3.66e-1)" "unprognostic (1.25e-2)" "unprognostic (1.44e-1)" "unprognostic (1.21e-1)" "unprognostic (7.46e-2)" "unprognostic (3.76e-1)" "unprognostic (1.95e-1)" "unprognostic (1.39e-3)" "unprognostic (1.45e-2)" "potential prognostic favorable (6.14e-4)" "unprognostic (1.09e-1)" "unprognostic (1.21e-3)" "unprognostic (3.80e-2)" "unprognostic (1.74e-1)" "unprognostic (2.49e-2)" "unprognostic (4.30e-1)" "unprognostic (1.97e-2)" "unprognostic (1.71e-1)" "unprognostic (2.29e-2)" "unprognostic (7.57e-2)" "potential prognostic unfavorable (9.90e-4)" "unprognostic (3.58e-1)" "unprognostic (6.32e-3)" "unprognostic (2.17e-2)" "unprognostic (1.30e-2)" "unprognostic (1.49e-1)" "unprognostic (1.52e-1)" "unprognostic (1.62e-2)" "unprognostic (2.09e-1)" MDH2 ENSG00000146701 "Malate dehydrogenase 2" P40926 7 76048051-76067508 "Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 652.9;tongue: 562.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 569.8;Esophageal basal cells: 563.5;Esophageal suprabasal cells: 690.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "heart muscle: 2302210838.2" "HPA019714, HPA019716, HPA019848, HPA026720" Enhanced Enhanced Mitochondria No No 8100000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 42 Mitochondria "HPA019714: , HPA019716: , HPA019848: , HPA026720: " "unprognostic (1.85e-1)" "unprognostic (5.60e-2)" "unprognostic (6.48e-2)" "unprognostic (1.52e-1)" "unprognostic (4.56e-3)" "unprognostic (7.76e-2)" "unprognostic (4.29e-3)" "unprognostic (7.59e-3)" "unprognostic (2.95e-2)" "unprognostic (1.16e-3)" "potential prognostic favorable (2.76e-4)" "unprognostic (2.45e-3)" "unprognostic (1.87e-3)" "unprognostic (6.77e-2)" "unprognostic (4.38e-3)" "unprognostic (2.46e-3)" "unprognostic (6.50e-2)" "unprognostic (1.17e-1)" "unprognostic (2.89e-1)" "unprognostic (6.69e-2)" "unprognostic (1.11e-1)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "unprognostic (6.93e-2)" "unprognostic (1.85e-2)" "unprognostic (2.54e-1)" "unprognostic (2.62e-1)" "unprognostic (1.84e-1)" "unprognostic (1.82e-2)" "unprognostic (4.40e-2)" "unprognostic (1.38e-2)" MDM2 "HDM2, MGC5370" ENSG00000135679 "MDM2 proto-oncogene" Q00987 12 68808177-68845544 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Ubl conjugation pathway" Transferase "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 661.7;Neutrophils: 371.8;Thymic myoid cells: 1042.8;Urothelial cells: 760.6" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 760.6;Ciliated cells: 661.7;Stromal cells: 1042.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 604 "Oocytes: 60383.4" "Not detected" "Not detected" "CAB000086, CAB016303, HPA045159, CAB079977" Supported Supported "Nucleoplasm,Centriolar satellite,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 6: Leukemia - Signal transduction" "Cluster 69: Urothelial cells - Basic cellular functions" 369 "Nucleoplasm, Cytosol" "Centriolar satellite, Mid piece, Principal piece, End piece" "CAB000086: , CAB016303: , CAB079977: , HPA045159: " "unprognostic (9.41e-2)" "unprognostic (6.79e-2)" "unprognostic (7.07e-2)" "unprognostic (1.74e-2)" "unprognostic (5.81e-2)" "unprognostic (1.53e-2)" "unprognostic (6.28e-2)" "potential prognostic unfavorable (3.17e-4)" "unprognostic (2.30e-1)" "unprognostic (6.72e-2)" "potential prognostic favorable (4.89e-5)" "unprognostic (3.36e-3)" "unprognostic (1.27e-1)" "unprognostic (1.03e-1)" "unprognostic (3.75e-2)" "unprognostic (2.28e-1)" "unprognostic (1.43e-1)" "unprognostic (9.98e-2)" "unprognostic (4.24e-3)" "unprognostic (6.18e-3)" "unprognostic (5.90e-2)" "validated prognostic unfavorable (3.14e-4)" "validated prognostic unfavorable (2.89e-5)" "unprognostic (1.67e-1)" "unprognostic (1.47e-1)" "unprognostic (3.23e-3)" "unprognostic (3.73e-3)" "unprognostic (8.38e-3)" "unprognostic (4.32e-1)" "unprognostic (3.24e-1)" "unprognostic (1.78e-2)" MEAF6 "C1orf149, CENP-28, Eaf6, FLJ11730, NY-SAR-91" ENSG00000163875 "MYST/Esa1 associated factor 6" Q9HAF1 1 37489993-37514766 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 327.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 5092227.6" HPA029599 Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 46 "Nuclear bodies" Nucleoplasm "HPA029599: " "unprognostic (7.08e-2)" "unprognostic (2.36e-1)" "unprognostic (7.85e-2)" "unprognostic (1.97e-1)" "unprognostic (2.98e-1)" "unprognostic (4.21e-2)" "unprognostic (1.06e-1)" "unprognostic (1.40e-3)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (9.48e-5)" "potential prognostic favorable (2.81e-7)" "unprognostic (2.86e-3)" "unprognostic (2.55e-1)" "unprognostic (4.55e-2)" "unprognostic (3.45e-2)" "unprognostic (5.91e-3)" "unprognostic (1.18e-1)" "unprognostic (1.00e-2)" "unprognostic (8.67e-2)" "unprognostic (1.41e-1)" "unprognostic (9.27e-2)" "unprognostic (9.34e-2)" "unprognostic (1.49e-1)" "unprognostic (4.40e-2)" "unprognostic (3.78e-3)" "unprognostic (5.61e-2)" "unprognostic (9.76e-2)" "unprognostic (2.08e-1)" "unprognostic (2.76e-1)" "unprognostic (1.40e-1)" "unprognostic (4.14e-2)" MED26 "CRSP7, CRSP70" ENSG00000105085 "Mediator complex subunit 26" O95402 19 16574907-16629062 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 34.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in all" 8 "Uterine Corpus Endometrial Carcinoma (TCGA): 92.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 444694.1;Neurons: 374641.4" "Group enriched" "Detected in some" 236 "bone marrow: 40266.9;lymphoid tissue: 12400.0;ovary: 18134.1" "HPA036798, HPA057997, HPA071835" Enhanced Approved "Nucleoplasm,Mitotic chromosome" Yes No "Cluster 32: Basophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 101 Nucleoplasm "Mitotic chromosome" "HPA036798: , HPA057997: , HPA071835: " "unprognostic (6.86e-3)" "unprognostic (7.81e-2)" "unprognostic (7.26e-2)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (1.49e-1)" "unprognostic (2.41e-1)" "unprognostic (6.50e-3)" "unprognostic (2.37e-2)" "unprognostic (6.85e-3)" "unprognostic (9.59e-2)" "unprognostic (1.07e-1)" "unprognostic (3.95e-1)" "unprognostic (6.81e-2)" "unprognostic (5.36e-3)" "unprognostic (5.98e-2)" "unprognostic (2.77e-1)" "unprognostic (4.60e-2)" "unprognostic (9.94e-2)" "unprognostic (2.70e-1)" "unprognostic (1.08e-3)" "unprognostic (7.02e-2)" "unprognostic (2.67e-2)" "unprognostic (3.27e-2)" "potential prognostic favorable (8.56e-4)" "unprognostic (1.51e-1)" "unprognostic (1.81e-2)" "unprognostic (4.59e-2)" "unprognostic (2.79e-2)" "unprognostic (2.75e-1)" MED31 "CGI-125, Soh1" ENSG00000108590 "Mediator complex subunit 31" Q9Y3C7 17 6643311-6651634 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 240.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 240.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2885 "Granulosa cells: 288523.6" "Tissue enriched" "Detected in single" 251 "lymphoid tissue: 25086.8" HPA035947 Uncertain Approved Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 2: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 135 Nucleoplasm "HPA035947: " "unprognostic (1.98e-1)" "unprognostic (6.28e-2)" "unprognostic (1.10e-3)" "unprognostic (1.03e-1)" "unprognostic (4.73e-2)" "unprognostic (1.27e-1)" "unprognostic (1.19e-1)" "unprognostic (1.89e-1)" "unprognostic (6.10e-2)" "unprognostic (7.11e-3)" "unprognostic (4.70e-2)" "unprognostic (2.30e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-2)" "unprognostic (3.94e-2)" "unprognostic (1.17e-2)" "unprognostic (1.83e-1)" "unprognostic (5.91e-2)" "unprognostic (1.39e-1)" "unprognostic (1.39e-2)" "unprognostic (7.61e-2)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (2.47e-2)" "unprognostic (8.22e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.20e-1)" "unprognostic (4.03e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" MED7 "CRSP33, CRSP9" ENSG00000155868 "Mediator complex subunit 7" O43513 5 157137424-157159019 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 47.9;Late primary spermatocytes: 16.1;Late spermatids: 30.5;Tuft cells: 11.5" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 47.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA067181 Supported "Nuclear bodies" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 100 "Nuclear bodies" "HPA067181: " "unprognostic (6.65e-3)" "unprognostic (2.31e-1)" "unprognostic (1.79e-1)" "unprognostic (9.22e-2)" "unprognostic (8.46e-2)" "unprognostic (6.00e-2)" "potential prognostic unfavorable (1.69e-6)" "unprognostic (4.02e-2)" "unprognostic (1.07e-2)" "unprognostic (2.17e-3)" "potential prognostic favorable (6.79e-10)" "unprognostic (4.09e-3)" "potential prognostic favorable (1.33e-4)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (2.73e-1)" "unprognostic (2.00e-2)" "unprognostic (2.12e-1)" "unprognostic (1.28e-1)" "unprognostic (3.04e-1)" "unprognostic (2.54e-2)" "unprognostic (1.82e-2)" "unprognostic (3.70e-1)" "unprognostic (5.74e-3)" "unprognostic (5.91e-2)" "potential prognostic favorable (4.09e-4)" "unprognostic (6.72e-2)" "unprognostic (5.84e-2)" "unprognostic (1.99e-1)" "unprognostic (1.75e-1)" "unprognostic (8.49e-2)" "unprognostic (4.75e-2)" MED9 "FLJ10193, MED25" ENSG00000141026 "Mediator complex subunit 9" Q9NWA0 17 17476994-17493221 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Collecting ducts: 87797.3;Fallopian tube cells: 110016.8;Macrophages: 130889.5;Neurons: 36420.5" "Low tissue specificity" "Detected in many" HPA056415 Uncertain Approved Nucleoplasm,Midbody Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 42: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 140 Nucleoplasm Midbody "HPA056415: " "unprognostic (1.14e-2)" "unprognostic (3.46e-1)" "unprognostic (1.67e-1)" "unprognostic (2.67e-1)" "unprognostic (3.14e-1)" "unprognostic (1.18e-1)" "unprognostic (3.79e-1)" "unprognostic (5.58e-3)" "unprognostic (2.36e-1)" "unprognostic (2.47e-1)" "validated prognostic favorable (2.82e-6)" "validated prognostic favorable (3.59e-4)" "unprognostic (1.52e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-1)" "unprognostic (1.75e-1)" "unprognostic (1.28e-1)" "unprognostic (1.63e-1)" "unprognostic (5.61e-1)" "unprognostic (1.40e-1)" "unprognostic (1.57e-1)" "potential prognostic favorable (2.14e-5)" "unprognostic (9.68e-2)" "unprognostic (6.55e-3)" "unprognostic (2.79e-2)" "unprognostic (1.42e-1)" "unprognostic (2.05e-1)" "unprognostic (7.74e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (2.32e-1)" MEF2A "RSRFC4, RSRFC9" ENSG00000068305 "Myocyte enhancer factor 2A" Q02078 15 99565417-99716488 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia: 3037.3;Neutrophils: 1663.6" "Cell type enhanced" "Detected in all" "Glial cells: 3037.3;Neutrophils: 1663.6" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 3820.0;endothelial cell: 1120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Capillaries: 316896.3;Cardiomyocytes: 197136.3" "Tissue enriched" "Detected in some" "heart muscle: 64404.3" "CAB004499, HPA046597, HPA056563" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 6: Leukemia - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 19 Nucleoplasm Cytosol "CAB004499: , HPA046597: , HPA056563: " "unprognostic (5.40e-2)" "unprognostic (2.89e-1)" "unprognostic (4.67e-3)" "unprognostic (2.23e-1)" "unprognostic (1.84e-1)" "unprognostic (2.87e-2)" "unprognostic (2.83e-1)" "unprognostic (1.76e-1)" "unprognostic (3.93e-1)" "unprognostic (7.81e-2)" "potential prognostic favorable (3.69e-6)" "unprognostic (1.94e-3)" "unprognostic (3.82e-3)" "unprognostic (2.23e-1)" "unprognostic (2.17e-1)" "unprognostic (8.08e-2)" "unprognostic (1.86e-2)" "unprognostic (3.27e-2)" "unprognostic (1.94e-1)" "unprognostic (2.43e-2)" "unprognostic (1.08e-3)" "unprognostic (1.68e-2)" "unprognostic (1.64e-2)" "unprognostic (4.03e-1)" "unprognostic (2.26e-1)" "unprognostic (5.91e-3)" "unprognostic (9.21e-3)" "unprognostic (2.53e-3)" "unprognostic (2.28e-1)" "unprognostic (2.51e-1)" "unprognostic (7.94e-3)" MEGF10 "KIAA1780, SR-F3" ENSG00000145794 "Multiple EGF like domains 10" Q96KG7 5 127290796-127465737 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Myogenesis, Phagocytosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.2;retina: 7.4" "Cell type enhanced" "Detected in many" "Astrocytes: 300.8;Ependymal cells: 70.4;Müller glia: 186.0;Myosatellite cells: 365.0;Oligodendrocyte progenitor cells: 108.9;Oligodendrocytes: 455.9;Other brain neurons: 109.2;Pituicytes/FSCs: 127.5;Pituitary stem cells: 80.8" "Cell type enhanced" "Detected in many" "Glial cells: 455.9;Neuronal cells: 109.2;Stem cells: 365.0" "Cell type enhanced" "Detected in all" "astrocyte: 343.9;cerebellar inhibitory: 510.3;oligodendrocyte: 637.4" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Sarcoma: 10.0;skin cancer: 6.9" "Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Liver - Hepatocytes, Minor Salivary Gland - Smooth muscle cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 6139 "bone marrow: 613857.9" HPA011401 Supported "Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 8100000 "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 80: Oligodendrocytes - Myelination" 1 "Plasma membrane" "HPA011401: " "unprognostic (6.64e-2)" "unprognostic (1.87e-1)" "unprognostic (5.66e-2)" "potential prognostic unfavorable (6.09e-4)" "unprognostic (6.15e-2)" "unprognostic (1.35e-3)" "unprognostic (4.93e-2)" "unprognostic (1.12e-1)" MEGF6 EGFL3 ENSG00000162591 "Multiple EGF like domains 6" O75095 1 3487951-3611508 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 85.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 40.2;Basal prostatic cells: 50.2;Epicardial cells: 100.1;Hepatic stellate cells: 71.0;Lymphatic endothelial cells: 42.8;Müller glia: 38.9;Salivary myoepithelial cells: 34.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 100.1;Stellate cells: 71.0" "Cell type enriched" "Detected in many" 4 "endothelial cell: 50.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 1.9" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 12586361.3" "Tissue enriched" "Detected in many" "blood vessel: 21405866.0" HPA052129 Uncertain Approved "Microtubules,Cytokinetic bridge" "Secreted to blood" "No annotated function" Yes No 250000 "Cluster 22: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 Microtubules "Cytokinetic bridge" "HPA052129: " "potential prognostic favorable (4.63e-4)" "unprognostic (1.69e-2)" "unprognostic (1.51e-1)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (4.15e-4)" "unprognostic (1.30e-1)" "unprognostic (1.39e-1)" "unprognostic (5.89e-2)" "potential prognostic favorable (2.30e-4)" "unprognostic (9.61e-2)" "unprognostic (1.89e-1)" "unprognostic (5.28e-2)" "unprognostic (6.71e-2)" "unprognostic (1.80e-1)" "unprognostic (1.81e-3)" "unprognostic (1.25e-2)" "unprognostic (1.17e-1)" "unprognostic (9.61e-2)" "unprognostic (7.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.78e-1)" "unprognostic (2.16e-2)" "unprognostic (8.81e-2)" "unprognostic (4.81e-1)" "unprognostic (2.05e-1)" "unprognostic (1.53e-3)" "unprognostic (6.65e-2)" "unprognostic (2.98e-1)" "unprognostic (9.82e-2)" "unprognostic (3.82e-3)" "unprognostic (1.02e-1)" MEIS1 ENSG00000143995 "Meis homeobox 1" O00470 2 66433452-66573869 "Predicted intracellular proteins, Transcription factors" Transcription "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 708.9;Endometrial stromal cells: 713.0;Hematopoietic stem cells: 994.7;Lacrimal acinar cells: 902.2;Megakaryocyte progenitors: 607.8;Mesothelial cells: 520.0;Rod photoreceptor cells: 591.2;Salivary acinar cells: 508.7" "Cell type enhanced" "Detected in many" "Acinar cells: 902.2;Stem cells: 994.7" "Cell type enhanced" "Detected in many" "Bergmann glia: 402.4;oligodendrocyte: 348.5;upper rhombic lip: 403.4" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 64.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 1.6;plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 38.0" "Breast - Fibroblasts, Kidney - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 2981409.1;Large ducts: 1500126.6;Pancreas epithelial cells: 1221164.4" "Tissue enhanced" "Detected in many" "pancreas: 9758624.2" "CAB011521, HPA056000, HPA058641" Approved Supported Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 6 Nucleoplasm "CAB011521: , HPA056000: , HPA058641: " "unprognostic (3.26e-2)" "unprognostic (1.58e-1)" "unprognostic (5.70e-3)" "unprognostic (2.16e-1)" "unprognostic (1.32e-1)" "unprognostic (7.05e-2)" "unprognostic (4.02e-1)" "unprognostic (7.36e-2)" "potential prognostic favorable (3.56e-5)" "unprognostic (1.22e-1)" "validated prognostic favorable (8.24e-4)" "validated prognostic favorable (6.10e-4)" "unprognostic (7.30e-3)" "unprognostic (1.15e-2)" "unprognostic (5.55e-3)" "unprognostic (3.03e-2)" "unprognostic (7.37e-2)" "unprognostic (3.34e-2)" "unprognostic (3.69e-1)" "unprognostic (2.98e-1)" "unprognostic (2.59e-1)" "unprognostic (7.08e-2)" "unprognostic (2.34e-2)" "unprognostic (4.97e-2)" "unprognostic (4.65e-1)" "unprognostic (2.20e-2)" "unprognostic (6.46e-2)" "unprognostic (2.51e-1)" "unprognostic (2.21e-1)" "unprognostic (2.60e-1)" MEOX1 MOX1 ENSG00000005102 "Mesenchyme homeobox 1" P50221 17 43640389-43661922 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 31.3;breast: 22.5;heart muscle: 22.4" "Cell type enriched" "Detected in some" 9 "Vascular endothelial cells: 62.3" "Cell type enriched" "Detected in many" 9 "Endothelial cells: 62.3" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 11.1" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 4 "T-reg: 17.5" "Lineage enriched" "Detected in single" 48 "T-cells: 17.5" "Group enriched" "Detected in many" 6 "ovarian cancer: 14.0;Rhabdoid: 19.9;Sarcoma: 5.1;Uterine cancer: 11.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Lung - Fibroblasts_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 792 "lymphoid tissue: 79192.7" "HPA045214, HPA063788" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 81 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA045214: , HPA063788: " "unprognostic (1.54e-1)" "unprognostic (1.60e-2)" "unprognostic (2.01e-3)" "unprognostic (2.77e-3)" "unprognostic (5.10e-2)" "unprognostic (3.14e-1)" "unprognostic (8.01e-2)" "unprognostic (7.81e-3)" "unprognostic (7.90e-2)" "unprognostic (7.95e-2)" "unprognostic (2.17e-2)" "unprognostic (2.63e-1)" "unprognostic (1.24e-1)" "unprognostic (1.15e-1)" "unprognostic (3.23e-1)" "unprognostic (6.91e-2)" "unprognostic (2.25e-1)" "unprognostic (7.39e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (1.41e-1)" MEPCE "BCDIN3, FLJ20257" ENSG00000146834 "Methylphosphate capping enzyme" Q7L2J0 7 100428322-100434126 "Essential proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 9.9;Epididymal basal cells: 13.8;Epididymal efferent duct ciliated cells: 10.9;Platelets: 17.0" "Cell type enhanced" "Detected in many" "Platelets: 17.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "salivary gland: 1018570.1" "CAB026384, HPA051587" Supported Approved "Nucleoplasm,Cell Junctions" NA Yes "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 39: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 200 Nucleoplasm "Cell Junctions" "CAB026384: , HPA051587: " "unprognostic (9.32e-2)" "unprognostic (5.44e-2)" "unprognostic (6.82e-2)" "unprognostic (1.79e-1)" "unprognostic (2.13e-2)" "unprognostic (2.14e-1)" "unprognostic (2.16e-1)" "unprognostic (2.37e-1)" "unprognostic (1.08e-1)" "unprognostic (3.22e-1)" "potential prognostic favorable (1.22e-6)" "unprognostic (2.46e-2)" "potential prognostic favorable (5.34e-6)" "unprognostic (2.69e-3)" "unprognostic (2.45e-3)" "unprognostic (2.16e-2)" "unprognostic (1.00e-1)" "unprognostic (3.23e-3)" "unprognostic (7.17e-2)" "unprognostic (2.16e-1)" "unprognostic (5.92e-1)" "unprognostic (1.88e-2)" "unprognostic (4.12e-1)" "unprognostic (1.57e-1)" "unprognostic (6.74e-2)" "unprognostic (2.39e-2)" "unprognostic (8.67e-2)" "unprognostic (4.95e-1)" "unprognostic (2.79e-1)" "unprognostic (4.25e-1)" "unprognostic (1.73e-1)" MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 89.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 246.3;Astrocytes: 223.7;Bergmann glia: 193.1;Choroid plexus epithelial cells: 188.0;Kupffer cells: 732.8;Macrophages: 427.7;Microglia: 378.9;monocytes: 167.3;Pituicytes/FSCs: 247.6" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 246.3;Glial cells: 378.9;Mononuclear phagocytes: 732.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 214.6;central nervous system macrophage: 478.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 11 "intermediate monocyte: 8.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.7" "Low cancer specificity" "Detected in many" "Adipose visceral - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 580163.5;Distal tubules: 515845.6;Microglia and Neuropil: 757508.9" "Group enriched" "Detected in some" "intestine: 1510319.4;lymphoid tissue: 4149250.9" "HPA036196, HPA075622" Enhanced Supported "Plasma membrane,Midbody,Cytosol,Acrosome,Mid piece,Principal piece" Yes NA 8400000 "Cluster 40: Monocytes - Innate immune response" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 11 "Plasma membrane" "Midbody, Cytosol, Acrosome, Mid piece, Principal piece" "HPA036196: , HPA075622: " "unprognostic (3.26e-1)" "unprognostic (2.03e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (8.83e-4)" "unprognostic (1.92e-2)" "unprognostic (1.05e-1)" "unprognostic (6.18e-2)" "unprognostic (6.39e-2)" "unprognostic (1.50e-1)" "unprognostic (1.20e-3)" "potential prognostic favorable (2.36e-6)" "unprognostic (6.69e-3)" "unprognostic (3.02e-1)" "unprognostic (7.89e-3)" "unprognostic (6.29e-3)" "unprognostic (1.14e-2)" "unprognostic (3.75e-2)" "unprognostic (1.59e-2)" "unprognostic (2.33e-2)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (1.42e-1)" "unprognostic (6.60e-2)" "unprognostic (4.06e-1)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (2.60e-1)" "unprognostic (1.63e-2)" "unprognostic (3.24e-1)" "unprognostic (1.40e-1)" "unprognostic (3.71e-2)" MESP1 "bHLHc5, MGC10676" ENSG00000166823 "Mesoderm posterior bHLH transcription factor 1" Q9BRJ9 15 89749875-89751249 "Predicted intracellular proteins, Transcription factors" "Notch signaling pathway, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.4;prostate: 21.4;skeletal muscle: 12.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 65.3;Breast secretory cells: 100.0;Oocytes: 170.4;Prostatic glandular cells: 76.2;Respiratory secretory cells: 61.2;Salivary duct cells: 56.3" "Cell type enhanced" "Detected in many" "Glandular cells: 76.2;Oocytes: 170.4;Secretory cells: 100.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Prostate Adenocarcinoma (TCGA): 16.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 23.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA069981 Supported Nucleoplasm,Nucleoli NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 3 Nucleoplasm Nucleoli "HPA069981: " "unprognostic (1.80e-2)" "unprognostic (1.11e-2)" "unprognostic (2.66e-1)" "unprognostic (7.42e-2)" "unprognostic (4.03e-3)" "unprognostic (9.11e-2)" "unprognostic (2.07e-1)" "unprognostic (4.05e-3)" "potential prognostic unfavorable (1.71e-4)" "unprognostic (1.90e-2)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.85e-1)" "unprognostic (5.20e-2)" "unprognostic (1.21e-1)" METTL14 KIAA1627 ENSG00000145388 "Methyltransferase 14, N6-adenosine-methyltransferase subunit" Q9HCE5 4 118685392-118715433 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 134.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 134.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 2570994.4" "Tissue enhanced" "Detected in many" "ovary: 1316981.2" HPA038002 Supported Supported Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 47: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 33 Nucleoplasm "HPA038002: " "unprognostic (2.17e-1)" "unprognostic (1.33e-1)" "unprognostic (3.67e-1)" "unprognostic (3.30e-3)" "unprognostic (3.51e-2)" "unprognostic (2.32e-1)" "unprognostic (1.99e-1)" "unprognostic (3.11e-1)" "unprognostic (3.09e-1)" "unprognostic (5.89e-3)" "validated prognostic favorable (6.57e-8)" "validated prognostic favorable (8.70e-5)" "unprognostic (1.46e-1)" "unprognostic (1.16e-1)" "unprognostic (7.94e-2)" "unprognostic (5.04e-2)" "unprognostic (6.07e-2)" "unprognostic (2.17e-1)" "unprognostic (1.23e-1)" "unprognostic (3.61e-2)" "unprognostic (8.30e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.10e-3)" "unprognostic (2.12e-1)" "unprognostic (6.10e-2)" "unprognostic (1.39e-1)" "unprognostic (1.80e-1)" "unprognostic (4.92e-2)" "unprognostic (4.93e-2)" METTL17 "FLJ20859, METT11D1" ENSG00000165792 "Methyltransferase like 17" Q9H7H0 14 20989973-20997035 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 107.2;Ocular epithelial cells: 108.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 107.2;Barrier epithelial cells: 108.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 4984659.0" "Tissue enhanced" "Detected in many" "cerebral cortex: 764984.6" "HPA002955, HPA059802" Uncertain Enhanced Nucleoplasm No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 100: Stratified epithelial cells - Barrier functions" 50 Nucleoplasm "HPA002955: , HPA059802: " "unprognostic (2.10e-1)" "unprognostic (6.86e-2)" "unprognostic (7.84e-2)" "unprognostic (6.25e-3)" "unprognostic (1.82e-2)" "unprognostic (7.65e-2)" "potential prognostic favorable (5.72e-4)" "unprognostic (1.85e-2)" "unprognostic (3.86e-2)" "unprognostic (1.11e-3)" "unprognostic (3.33e-2)" "potential prognostic favorable (3.90e-4)" "unprognostic (3.18e-3)" "unprognostic (2.56e-2)" "unprognostic (1.32e-1)" "unprognostic (1.77e-1)" "unprognostic (3.27e-1)" "unprognostic (9.98e-2)" "unprognostic (1.50e-1)" "unprognostic (1.83e-2)" "unprognostic (2.94e-1)" "unprognostic (2.16e-2)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (4.67e-2)" "unprognostic (2.32e-1)" "unprognostic (5.51e-2)" "unprognostic (1.13e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (8.76e-4)" METTL22 "C16orf68, FLJ12433,MGC2654" ENSG00000067365 "Methyltransferase 22, Kin17 lysine" Q9BUU2 16 8621683-8649654 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Late spermatids: 641.8" "Cell type enriched" "Detected in all" 7 "Spermatogenic cell types: 641.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040803, HPA059882, HPA074173" Uncertain Supported "Nucleoplasm,Nucleoli rim" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 54: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 3 "Nucleoli rim" Nucleoplasm "HPA040803: , HPA059882: , HPA074173: " "unprognostic (2.35e-1)" "unprognostic (2.52e-1)" "unprognostic (3.94e-3)" "unprognostic (1.38e-1)" "unprognostic (4.34e-2)" "unprognostic (1.19e-1)" "unprognostic (4.98e-3)" "unprognostic (9.89e-2)" "unprognostic (1.58e-3)" "potential prognostic unfavorable (6.11e-6)" "unprognostic (1.90e-2)" "unprognostic (2.65e-2)" "unprognostic (3.79e-2)" "unprognostic (6.87e-2)" "unprognostic (2.90e-1)" "unprognostic (7.62e-2)" "unprognostic (2.12e-1)" "unprognostic (1.58e-2)" "unprognostic (5.26e-2)" "unprognostic (2.58e-1)" "potential prognostic favorable (7.99e-4)" "potential prognostic unfavorable (6.97e-4)" "unprognostic (1.61e-1)" "unprognostic (7.51e-2)" "unprognostic (1.80e-2)" "unprognostic (1.04e-1)" "unprognostic (3.47e-3)" "unprognostic (2.81e-1)" "unprognostic (3.70e-2)" "unprognostic (1.37e-2)" METTL23 "C17orf95, LOC124512" ENSG00000181038 "Methyltransferase like 23" Q86XA0 17 76726830-76733936 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 77.8;Late primary spermatocytes: 203.9" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 203.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA022889 Approved Vesicles No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Vesicles "HPA022889: " "unprognostic (9.50e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-1)" "unprognostic (3.08e-1)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (1.45e-1)" "unprognostic (5.02e-2)" "unprognostic (6.26e-2)" "unprognostic (1.63e-2)" "unprognostic (3.45e-2)" "unprognostic (1.31e-1)" "validated prognostic unfavorable (5.32e-6)" "validated prognostic unfavorable (3.67e-4)" "unprognostic (1.87e-2)" "unprognostic (3.13e-2)" "unprognostic (5.62e-2)" "unprognostic (1.52e-1)" "unprognostic (1.66e-1)" "unprognostic (1.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.52e-1)" "unprognostic (8.05e-2)" "unprognostic (5.43e-3)" "unprognostic (8.86e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-2)" "unprognostic (1.90e-1)" "unprognostic (1.50e-1)" "unprognostic (2.92e-2)" METTL27 WBSCR27 ENSG00000165171 "Methyltransferase like 27" Q8N6F8 7 73834590-73842516 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.1" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 63.9;Enterocytes: 44.3;Epididymal efferent duct ciliated cells: 102.0;Fallopian tube ciliated cells: 75.7;Gastric progenitor cells: 44.9;Megakaryocytes: 49.5;Respiratory ciliated cells: 89.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 102.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 12.1;ependymal cell: 20.4" "Cancer enriched" "Detected in all" 4 "Kidney Renal Papillary Cell Carcinoma (TCGA): 64.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA074662 Approved Approved Mitochondria,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 107: Ciliated cells - Cilia assembly & function" 43 "Mitochondria, Cytosol" "HPA074662: " "unprognostic (5.99e-3)" "unprognostic (1.28e-1)" "unprognostic (9.43e-2)" "unprognostic (3.65e-3)" "unprognostic (2.03e-1)" "unprognostic (4.98e-3)" "unprognostic (1.93e-2)" "unprognostic (1.80e-2)" "unprognostic (1.09e-1)" "validated prognostic favorable (2.17e-7)" "validated prognostic favorable (4.36e-5)" "potential prognostic favorable (3.64e-5)" "unprognostic (3.44e-3)" "unprognostic (1.60e-1)" "unprognostic (1.47e-3)" "unprognostic (9.58e-2)" "unprognostic (2.48e-1)" "unprognostic (2.10e-1)" "unprognostic (1.64e-1)" "unprognostic (5.47e-2)" "unprognostic (1.89e-1)" "unprognostic (1.57e-1)" "unprognostic (2.74e-1)" "unprognostic (1.23e-1)" "unprognostic (1.59e-1)" "unprognostic (8.89e-2)" "unprognostic (2.46e-2)" "unprognostic (4.66e-2)" "unprognostic (2.69e-2)" METTL6 MGC24132 ENSG00000206562 "Methyltransferase 6, methylcytidine" Q8TCB7 3 15381275-15440566 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 263.9;Epicardial cells: 136.4;Late primary spermatocytes: 178.7;Late spermatids: 160.1" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 136.4;Spermatogenic cell types: 263.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA035166 Uncertain Approved Vesicles No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 7 Vesicles "HPA035166: " "unprognostic (9.42e-2)" "unprognostic (5.34e-2)" "unprognostic (4.25e-2)" "unprognostic (7.06e-3)" "unprognostic (3.86e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-1)" "unprognostic (6.74e-3)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (9.27e-6)" "unprognostic (1.42e-1)" "unprognostic (3.17e-1)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (3.20e-7)" "unprognostic (1.02e-3)" "unprognostic (1.72e-2)" "unprognostic (2.23e-2)" "unprognostic (1.58e-1)" "unprognostic (6.60e-2)" "unprognostic (2.43e-1)" "unprognostic (2.34e-3)" "unprognostic (3.48e-1)" "unprognostic (8.04e-3)" "unprognostic (7.76e-2)" "potential prognostic favorable (1.43e-4)" "unprognostic (2.31e-2)" "unprognostic (7.55e-2)" "unprognostic (5.56e-3)" "unprognostic (1.83e-1)" "unprognostic (3.95e-3)" "unprognostic (6.58e-2)" METTL7B "ALDI, MGC17301" ENSG00000170439 "Methyltransferase like 7B" Q6UX53 12 55681736-55684611 "Enzymes, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 126.1;heart muscle: 136.0;liver: 267.4" "Cell type enhanced" "Detected in some" "Colonocytes: 33.8;Enteric transient amplifying cells: 30.9;Enterocytes: 181.6;Epididymal efferent duct absorptive cells: 86.2;Epididymal principal cells: 136.3;Hepatocytes: 93.1;Hofbauer cells: 166.6;Kupffer cells: 34.8;Pituicytes/FSCs: 37.2" "Cell type enhanced" "Detected in many" "Ductal cells: 86.2;Enterocytes: 181.6;Hepatocytes: 93.1;Mononuclear phagocytes: 166.6;Reproductive supporting cells: 136.3" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 5.0;hippocampal CA4: 11.0;hippocampal dentate gyrus: 12.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 181.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "intermediate monocyte: 4.5;myeloid DC: 7.0;naive B-cell: 1.7;non-classical monocyte: 3.3" "Group enriched" "Detected in many" 44 "B-cells: 1.7;dendritic cells: 7.0;monocytes: 4.5" "Cancer enhanced" "Detected in many" "colorectal cancer: 44.0" "Kidney - Proximal tubular cells, Skin - Sebaceous gland cells" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" "Glomeruli: 8580237.6;Hepatocytes: 24820298.8;Proximal tubules: 13040980.3" "Tissue enriched" "Detected in many" "liver: 24903877.3" HPA038644 Enhanced Approved Vesicles,Microtubules NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" Microtubules Vesicles "HPA038644: " "unprognostic (7.50e-3)" "unprognostic (7.09e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-1)" "unprognostic (1.48e-1)" "unprognostic (5.22e-2)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (6.59e-4)" "potential prognostic unfavorable (4.27e-4)" "unprognostic (1.72e-1)" "unprognostic (1.60e-3)" "unprognostic (2.63e-1)" "unprognostic (5.92e-2)" "unprognostic (2.09e-1)" "unprognostic (3.07e-2)" "unprognostic (3.50e-1)" "unprognostic (5.31e-2)" "unprognostic (1.64e-2)" "unprognostic (1.22e-1)" "unprognostic (1.50e-1)" "unprognostic (1.77e-1)" "unprognostic (1.50e-2)" "unprognostic (2.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.84e-1)" "unprognostic (1.21e-1)" "unprognostic (4.22e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (4.84e-4)" "unprognostic (2.92e-2)" MEX3B "DKFZp434J0617, RKHD3, RNF195" ENSG00000183496 "Mex-3 RNA binding family member B" Q6ZN04 15 82041778-82046119 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 12.4;testis: 45.1" "Group enriched" "Detected in many" 7 "Early spermatids: 264.0;Late spermatids: 304.0" "Cell type enriched" "Detected in many" 9 "Spermatogenic cell types: 304.0" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 24.4" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 214 "Collecting ducts: 19195.1;Neurons: 23648.6" "Not detected" "Not detected" HPA041093 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 11 "Nucleoplasm, Cytosol" "HPA041093: " "unprognostic (1.45e-1)" "unprognostic (1.85e-1)" "unprognostic (1.79e-1)" "unprognostic (1.30e-1)" "unprognostic (8.22e-3)" "unprognostic (2.87e-2)" "unprognostic (4.19e-1)" "unprognostic (1.24e-3)" "unprognostic (2.26e-1)" "unprognostic (2.55e-2)" "unprognostic (1.12e-1)" "unprognostic (1.63e-1)" "unprognostic (3.56e-1)" "unprognostic (1.05e-1)" "unprognostic (2.08e-2)" "unprognostic (2.06e-1)" "unprognostic (1.17e-1)" "unprognostic (3.48e-1)" "unprognostic (2.73e-1)" "unprognostic (2.20e-1)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (9.18e-4)" "unprognostic (1.99e-1)" "unprognostic (6.45e-2)" "unprognostic (2.56e-2)" "unprognostic (5.29e-2)" "unprognostic (8.32e-2)" "unprognostic (8.32e-2)" MFAP1 AMP ENSG00000140259 "Microfibril associated protein 1" P55081 15 43804492-43824690 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 183.9" "Cell type enhanced" "Detected in all" "Trophoblast cells: 183.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 21628610.7" "Low tissue specificity" "Detected in many" "HPA015583, HPA042370" Uncertain Supported Nucleoplasm,Centrosome NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 139 Nucleoplasm Centrosome "HPA015583: , HPA042370: " "unprognostic (2.97e-1)" "unprognostic (2.01e-2)" "unprognostic (2.21e-1)" "unprognostic (6.35e-2)" "unprognostic (4.30e-2)" "unprognostic (3.40e-2)" "unprognostic (3.39e-1)" "unprognostic (8.97e-2)" "unprognostic (3.58e-2)" "unprognostic (2.07e-2)" "validated prognostic favorable (2.07e-9)" "validated prognostic favorable (1.55e-4)" "unprognostic (3.67e-2)" "validated prognostic unfavorable (5.12e-6)" "validated prognostic unfavorable (2.80e-4)" "unprognostic (7.31e-2)" "unprognostic (9.89e-2)" "unprognostic (1.18e-1)" "unprognostic (1.73e-2)" "unprognostic (5.79e-2)" "unprognostic (9.44e-2)" "unprognostic (2.74e-2)" "unprognostic (1.24e-2)" "unprognostic (1.54e-1)" "unprognostic (1.39e-1)" "unprognostic (1.97e-2)" "unprognostic (5.50e-2)" "unprognostic (1.03e-1)" "unprognostic (6.68e-2)" "unprognostic (6.70e-2)" "unprognostic (3.51e-2)" MFF "C2orf33, GL004" ENSG00000168958 "Mitochondrial fission factor" Q9GZY8 2 227325151-227357833 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 5 "Early spermatids: 894.0;Late primary spermatocytes: 1010.9;Late spermatids: 3172.8" "Cell type enriched" "Detected in all" 10 "Spermatogenic cell types: 3172.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "cerebral cortex: 3672582.7" "HPA010968, HPA074625" Enhanced Supported "Mitochondria,Principal piece" No No 15000 "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 13 Mitochondria "Principal piece" "HPA010968: , HPA074625: " "unprognostic (2.76e-1)" "unprognostic (6.85e-3)" "unprognostic (5.10e-2)" "unprognostic (1.68e-1)" "unprognostic (7.94e-2)" "unprognostic (1.61e-1)" "unprognostic (9.66e-2)" "unprognostic (2.83e-2)" "unprognostic (1.82e-2)" "unprognostic (9.37e-3)" "potential prognostic favorable (2.12e-5)" "unprognostic (1.56e-3)" "unprognostic (1.22e-1)" "validated prognostic unfavorable (6.74e-7)" "validated prognostic unfavorable (1.16e-4)" "potential prognostic unfavorable (4.52e-4)" "unprognostic (3.58e-1)" "unprognostic (1.57e-1)" "unprognostic (2.62e-1)" "unprognostic (1.31e-1)" "unprognostic (3.09e-1)" "unprognostic (1.14e-1)" "unprognostic (7.62e-2)" "unprognostic (3.22e-3)" "unprognostic (9.10e-2)" "unprognostic (7.54e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (3.30e-2)" "unprognostic (1.91e-1)" "unprognostic (1.29e-1)" MFN2 "CMT2A2, CPRP1, KIAA0214, MARF" ENSG00000116688 "Mitofusin 2" O95140 1 11980181-12015211 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy, Unfolded protein response" Hydrolase "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 253.1;skeletal muscle: 290.9;tongue: 315.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 144.9;Neutrophils: 256.3;Platelets: 260.5" "Cell type enhanced" "Detected in all" "Neutrophils: 256.3;Platelets: 260.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 23519971.1" "HPA030554, CAB079902" Uncertain Supported Mitochondria NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 25 Mitochondria "CAB079902: , HPA030554: " "unprognostic (2.03e-1)" "unprognostic (2.68e-2)" "unprognostic (3.91e-2)" "unprognostic (2.74e-3)" "potential prognostic favorable (8.00e-4)" "unprognostic (3.71e-1)" "unprognostic (1.75e-1)" "unprognostic (1.93e-1)" "unprognostic (2.64e-1)" "unprognostic (7.47e-2)" "validated prognostic favorable (2.58e-8)" "validated prognostic favorable (2.81e-4)" "unprognostic (4.22e-3)" "unprognostic (3.10e-1)" "unprognostic (3.05e-2)" "unprognostic (1.31e-1)" "unprognostic (2.96e-1)" "unprognostic (7.22e-2)" "unprognostic (1.08e-1)" "unprognostic (2.60e-2)" "unprognostic (1.44e-1)" "unprognostic (1.43e-2)" "unprognostic (1.99e-2)" "unprognostic (7.49e-2)" "unprognostic (1.10e-1)" "unprognostic (3.58e-1)" "unprognostic (4.88e-1)" "unprognostic (6.91e-2)" "unprognostic (8.16e-2)" "unprognostic (6.10e-2)" "unprognostic (1.45e-1)" MFNG ENSG00000100060 "MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" O00587 22 37469063-37486393 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 64.6" "Cell type enhanced" "Detected in many" "B-cells: 31.1;cDC: 36.0;Hofbauer cells: 37.3;Kupffer cells: 32.8;Lymphatic endothelial cells: 46.7;Megakaryocyte progenitors: 65.6;Megakaryocyte-Erythroid progenitors: 34.5;Megakaryocytes: 173.1;monocytes: 34.6;NK-cells: 41.7;Platelets: 138.0;T-cells: 35.3;Vascular endothelial cells: 39.9" "Cell type enhanced" "Detected in many" "Megakaryocytes: 173.1;Platelets: 138.0" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 16.1;endothelial cell: 25.7;leukocyte: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 149.5;lymphoma: 165.2;Myeloma: 119.2" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 24 "lymphoid tissue: 2367.4" "HPA048936, HPA056479" Approved Approved Vesicles "Intracellular and membrane" "Developmental protein" NA NA 60000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 47: Platelets - Hemostasis" Vesicles "HPA048936: , HPA056479: " "unprognostic (6.07e-2)" "unprognostic (3.47e-1)" "unprognostic (6.31e-2)" "unprognostic (8.93e-3)" "unprognostic (3.07e-2)" "unprognostic (1.53e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (9.12e-3)" "unprognostic (1.26e-1)" "unprognostic (2.30e-3)" "unprognostic (2.56e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-1)" "unprognostic (5.21e-2)" "potential prognostic favorable (3.92e-4)" "unprognostic (2.58e-1)" "unprognostic (7.56e-2)" "unprognostic (4.75e-1)" "unprognostic (1.74e-1)" "unprognostic (8.60e-2)" "unprognostic (2.88e-2)" "unprognostic (2.94e-2)" "unprognostic (1.57e-2)" "unprognostic (2.42e-1)" "unprognostic (3.39e-1)" "unprognostic (4.52e-1)" "unprognostic (2.46e-1)" "unprognostic (4.24e-2)" "unprognostic (3.21e-1)" "unprognostic (9.15e-2)" MFSD10 "IT10C3, TETRAN" ENSG00000109736 "Major facilitator superfamily domain containing 10" Q14728 4 2930561-2934834 "Predicted membrane proteins" "Apoptosis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 41297666.4" "Tissue enhanced" "Detected in many" "ovary: 2483486.3" HPA043209 Uncertain Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 15: Non-specific - Protein processing" 8 "Nuclear membrane" Nucleoplasm "HPA043209: " "unprognostic (2.21e-1)" "unprognostic (6.16e-3)" "unprognostic (1.26e-2)" "unprognostic (4.03e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "unprognostic (3.51e-3)" "unprognostic (1.59e-1)" "unprognostic (2.20e-2)" "unprognostic (1.79e-1)" "unprognostic (4.73e-3)" "unprognostic (7.51e-3)" "unprognostic (9.35e-2)" "potential prognostic unfavorable (9.77e-6)" "unprognostic (1.18e-1)" "unprognostic (5.03e-2)" "unprognostic (1.09e-2)" "unprognostic (2.40e-2)" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "unprognostic (4.01e-3)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" "unprognostic (2.40e-3)" "unprognostic (4.40e-2)" "unprognostic (1.87e-1)" "unprognostic (7.92e-2)" "unprognostic (8.04e-2)" "unprognostic (2.06e-1)" "unprognostic (4.73e-2)" "unprognostic (1.05e-1)" MGARP "C4orf49, CESP-1, HUMMR, OSAP" ENSG00000137463 "Mitochondria localized glutamic acid rich protein" Q8TDB4 4 139266165-139280225 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 215.3;retina: 108.3" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 120.1;Granulosa cells: 77.9;Müller glia: 352.9;Ocular epithelial cells: 408.6;Retinal amacrine cells: 59.2;Retinal bipolar cells: 76.7;Retinal horizontal cells: 100.2" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 120.1;Barrier epithelial cells: 408.6;Glial cells: 352.9;Neuronal cells: 100.2" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 7.3;upper rhombic lip: 8.3" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 5.6;Kidney Renal Clear Cell Carcinoma (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Rhabdoid: 47.0" "Adipose visceral - Mesothelial cells, Pituitary gland - Thyrotropes, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 28.0" "Cell type enriched" "Detected in some" "Granulosa cells: 20645696.4" "Group enriched" "Detected in some" 15182 "kidney: 868991.3;ovary: 2167383.4" "HPA015994, HPA070835" Enhanced Supported Mitochondria NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 5: Rhabdoid - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 132 Mitochondria "HPA015994: , HPA070835: " "unprognostic (1.20e-2)" "potential prognostic unfavorable (1.06e-6)" "potential prognostic favorable (7.74e-7)" "unprognostic (5.94e-3)" "unprognostic (5.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.02e-1)" "unprognostic (1.52e-1)" MGAT4A "GnT-4a, GnT-Iva" ENSG00000071073 "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A" Q9UM21 2 98619106-98731132 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 90.5" "Cell type enhanced" "Detected in many" "Microglia: 851.4;Neutrophil progenitors: 259.4;T-cells: 237.1" "Cell type enhanced" "Detected in all" "Glial cells: 851.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 1092.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Skin - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Pancreas epithelial cells: 672836.7;Pancreatic islets: 602344.6" "Group enriched" "Detected in some" 5204 "pancreas: 669922.1;salivary gland: 370888.6" HPA007608 Enhanced Approved "Golgi apparatus" "Secreted to blood" Enzyme NA NA "Cluster 11: T-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Golgi apparatus" "HPA007608: " "unprognostic (2.90e-3)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.02e-1)" "unprognostic (9.14e-2)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (3.62e-2)" "unprognostic (2.27e-1)" "unprognostic (2.96e-2)" "potential prognostic favorable (4.38e-5)" "unprognostic (2.09e-3)" "unprognostic (3.12e-1)" "unprognostic (1.15e-2)" "unprognostic (1.53e-2)" "unprognostic (8.19e-3)" "unprognostic (2.99e-2)" "unprognostic (4.59e-2)" "unprognostic (2.35e-1)" "unprognostic (3.16e-1)" "unprognostic (3.28e-3)" "unprognostic (1.33e-1)" "unprognostic (2.26e-2)" "unprognostic (7.57e-2)" "unprognostic (1.58e-1)" "unprognostic (1.24e-1)" "unprognostic (1.42e-1)" "unprognostic (2.89e-2)" "unprognostic (1.69e-1)" "unprognostic (8.81e-2)" "potential prognostic unfavorable (1.30e-4)" MGAT5B "FLJ25132, GnT-IX, GnT-VB" ENSG00000167889 "Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B" Q3V5L5 17 76868404-76950393 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "brain: 39.4" "Cell type enhanced" "Detected in some" "Astrocytes: 15.7;Bergmann glia: 56.3;Brain excitatory neurons: 29.3;Brain inhibitory neurons: 38.2;Early spermatids: 15.4;Gonadotrophs: 12.6;Late spermatids: 18.8;Oocytes: 73.7;Other brain neurons: 12.8;Retinal amacrine cells: 30.5;Retinal ganglion cells: 19.3;Thyrotrophs: 11.2" "Cell type enhanced" "Detected in some" "Glial cells: 56.3;Neuronal cells: 38.2;Oocytes: 73.7;Spermatogenic cell types: 18.8" "Cell type enhanced" "Detected in many" "upper-layer intratelencephalic: 117.4" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 12.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 3108 "Neurons: 310768.0" "Not detected" "Not detected" HPA011082 Approved "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 2 "Nucleoplasm, Mitotic spindle" "Cytokinetic bridge" "HPA011082: " "unprognostic (3.89e-1)" "unprognostic (1.33e-2)" "unprognostic (2.08e-2)" "unprognostic (5.10e-2)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" MGST1 "GST12, MGST-I, PMAN" ENSG00000008394 "Microsomal glutathione S-transferase 1" P10620 12 16347142-16609259 "Enzymes, Metabolic proteins, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1028.7;adrenal gland: 1044.9;liver: 2898.8" "Cell type enhanced" "Detected in many" "Adipocytes: 1314.2;Alveolar cells type 1: 1350.9;Alveolar cells type 2: 2177.9;Endometrial glandular cells: 1213.7;Hepatocytes: 5068.2;Respiratory secretory cells: 1122.4;Transitional alveolar cells: 1536.8;Urothelial cells: 1075.1" "Cell type enhanced" "Detected in all" "Alveolar cells: 2177.9;Hepatocytes: 5068.2" "Cell type enhanced" "Detected in all" "astrocyte: 527.2;Bergmann glia: 723.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 171.3;myeloid DC: 124.0" "Group enriched" "Detected in many" 13 "dendritic cells: 124.0;monocytes: 171.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Colon - Macrophages, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 16542954.7;Neutrophils: 9656343.5" "Group enriched" "Detected in many" "bone marrow: 1207361.8;liver: 1935626.0" HPA044840 Enhanced Approved "Endoplasmic reticulum,Mitochondria" NA NA 34000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 76: Non-specific - Metabolism" "Cluster 46: Brainstem - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 81: Alveolar cells - Lung function" 11 Mitochondria "Endoplasmic reticulum" "HPA044840: " "unprognostic (3.26e-1)" "unprognostic (3.06e-2)" "unprognostic (6.44e-2)" "unprognostic (9.71e-3)" "unprognostic (8.55e-2)" "unprognostic (3.35e-2)" "unprognostic (1.84e-3)" "unprognostic (3.46e-1)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "unprognostic (3.26e-2)" "unprognostic (1.89e-2)" "unprognostic (3.89e-3)" "unprognostic (1.09e-1)" "unprognostic (5.80e-2)" "unprognostic (1.64e-2)" "unprognostic (3.74e-1)" "unprognostic (9.85e-3)" "unprognostic (6.90e-2)" "unprognostic (8.26e-2)" "unprognostic (2.65e-1)" "unprognostic (4.02e-3)" "potential prognostic unfavorable (4.87e-4)" "unprognostic (2.51e-1)" "unprognostic (1.79e-1)" "unprognostic (2.93e-2)" "unprognostic (6.35e-2)" "unprognostic (2.10e-1)" "unprognostic (4.83e-1)" "unprognostic (8.81e-3)" "unprognostic (1.57e-3)" MGST2 MGST-II ENSG00000085871 "Microsomal glutathione S-transferase 2" Q99735 4 139665768-139740745 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Leukotriene biosynthesis, Lipid metabolism" "Lyase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 366.8" "Cell type enhanced" "Detected in many" "Breast lactating cells: 490.9;Esophageal apical cells: 1055.4;Esophageal basal cells: 479.5;Esophageal suprabasal cells: 847.6;Gastric progenitor cells: 775.4;Hepatocytes: 513.1;Hofbauer cells: 691.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1055.4;Proliferating cells: 775.4;Suprabasal cells: 847.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 158.6;endothelial cell: 209.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 195.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 61231404.1" "Tissue enriched" "Detected in many" "liver: 27262090.9" "HPA010690, HPA010707" Enhanced Uncertain "Endoplasmic reticulum,Cytosol" NA NA 11000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 22 Cytosol "Endoplasmic reticulum" "HPA010690: , HPA010707: " "unprognostic (6.09e-2)" "unprognostic (1.77e-2)" "unprognostic (4.33e-2)" "unprognostic (1.92e-1)" "unprognostic (2.07e-3)" "unprognostic (3.07e-1)" "unprognostic (2.04e-2)" "unprognostic (5.70e-2)" "unprognostic (1.32e-1)" "unprognostic (2.30e-1)" "validated prognostic favorable (2.25e-10)" "validated prognostic favorable (3.05e-5)" "potential prognostic favorable (6.42e-4)" "unprognostic (1.67e-3)" "unprognostic (9.07e-3)" "unprognostic (9.83e-2)" "unprognostic (1.05e-1)" "unprognostic (1.46e-1)" "unprognostic (1.83e-1)" "unprognostic (7.77e-2)" "unprognostic (3.89e-2)" "unprognostic (1.36e-1)" "unprognostic (2.99e-1)" "unprognostic (2.14e-1)" "unprognostic (2.23e-1)" "unprognostic (1.17e-1)" "unprognostic (1.03e-1)" "unprognostic (3.70e-1)" "unprognostic (5.75e-1)" "unprognostic (7.20e-2)" "unprognostic (1.17e-2)" MIA3 "FLJ39207, KIAA0268, TANGO, TANGO1, UNQ6077" ENSG00000154305 "MIA SH3 domain ER export factor 3" Q5JRA6 1 222618097-222668007 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "ER-Golgi transport, Exocytosis, Protein transport, Transport" "Deafness, Diabetes mellitus, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 304.2" "Cell type enhanced" "Detected in all" "Glandular cells: 304.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islets: 85928350.6" "Tissue enhanced" "Detected in all" "salivary gland: 53098816.2" "HPA055922, HPA056816" Supported Enhanced Vesicles NA NA 4400000 "Cluster 35: Neutrophils - Protein binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 26 Vesicles "HPA055922: , HPA056816: " "unprognostic (5.23e-2)" "unprognostic (2.24e-1)" "unprognostic (1.98e-1)" "unprognostic (6.98e-2)" "unprognostic (1.22e-1)" "unprognostic (2.94e-2)" "unprognostic (5.70e-2)" "unprognostic (4.05e-1)" "unprognostic (5.09e-2)" "unprognostic (4.07e-2)" "potential prognostic favorable (2.10e-4)" "unprognostic (3.68e-1)" "unprognostic (1.02e-2)" "unprognostic (5.41e-3)" "potential prognostic favorable (4.57e-4)" "unprognostic (1.19e-1)" "unprognostic (1.66e-1)" "unprognostic (2.36e-1)" "unprognostic (6.07e-2)" "unprognostic (1.88e-1)" "unprognostic (9.98e-2)" "unprognostic (3.74e-2)" "unprognostic (1.12e-1)" "unprognostic (3.72e-2)" "unprognostic (2.48e-1)" "unprognostic (2.16e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (4.19e-1)" "unprognostic (1.77e-2)" "unprognostic (2.47e-1)" MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "MIB E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2576.9;Myonuclei: 980.3;Podocytes: 526.0" "Cell type enriched" "Detected in all" 4 "Myocytes: 2576.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 6614773.4" "HPA019100, CAB037044, HPA067539" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centriolar satellite,Basal body" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 50 "Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Centriolar satellite, Basal body" "CAB037044: , HPA019100: , HPA067539: " "unprognostic (4.48e-2)" "unprognostic (2.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-3)" "unprognostic (3.78e-2)" "unprognostic (1.48e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (7.18e-4)" "unprognostic (5.01e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.18e-4)" "unprognostic (3.54e-2)" "unprognostic (4.29e-2)" "unprognostic (1.52e-2)" "unprognostic (3.09e-2)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (2.79e-1)" "unprognostic (1.16e-2)" "unprognostic (8.92e-2)" "unprognostic (1.10e-2)" "unprognostic (3.80e-2)" "unprognostic (5.02e-2)" "unprognostic (3.54e-2)" "unprognostic (2.25e-1)" "unprognostic (4.68e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-2)" "unprognostic (3.81e-1)" "unprognostic (2.00e-2)" "unprognostic (1.56e-1)" MICAL1 "DKFZp434B1517, FLJ11937, FLJ21739, MICAL, NICAL" ENSG00000135596 "Microtubule associated monooxygenase, calponin and LIM domain containing 1" Q8TDZ2 6 109444062-109465968 "Enzymes, Predicted intracellular proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 57.9;Decidual stromal cells: 62.1;Goblet cells: 57.8;Neutrophil progenitors: 85.3;Neutrophils: 86.3;pDCs: 59.8;Smooth muscle cells: 66.6;Vascular smooth muscle cells: 58.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 35475897.6;T-cells: 26311167.5" "Tissue enhanced" "Detected in many" "lymphoid tissue: 77293044.0" "HPA030175, HPA030176, HPA030178" Approved Approved "Nucleoplasm,Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 30: White matter - Myelination" "Cluster 35: RS4;11 - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Nucleoplasm, Primary cilium, Cytosol" "Plasma membrane, Basal body" "HPA030175: , HPA030176: , HPA030178: " "unprognostic (1.15e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-1)" "unprognostic (1.14e-2)" "unprognostic (7.31e-2)" "unprognostic (6.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.74e-3)" "unprognostic (1.46e-2)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (7.72e-4)" "unprognostic (3.29e-1)" "unprognostic (2.27e-2)" "unprognostic (9.54e-3)" "unprognostic (1.29e-1)" "unprognostic (3.94e-3)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.65e-1)" "unprognostic (1.07e-2)" "unprognostic (6.58e-2)" "potential prognostic favorable (3.16e-6)" "unprognostic (2.90e-2)" "unprognostic (1.96e-1)" "unprognostic (2.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.06e-1)" "unprognostic (1.59e-1)" "unprognostic (1.54e-1)" "unprognostic (1.75e-1)" "unprognostic (1.05e-1)" MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 429.5;Choroid plexus epithelial cells: 439.4;Myonuclei: 337.3;Oligodendrocytes: 359.7;Proximal tubule cells: 365.9" "Cell type enhanced" "Detected in all" "Ciliated cells: 439.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "basophil: 11.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.2" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 31161613.9" "Low tissue specificity" "Detected in many" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 6 "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: , HPA003421: , HPA034882: " "unprognostic (2.56e-1)" "unprognostic (8.71e-2)" "unprognostic (2.78e-2)" "unprognostic (2.43e-2)" "unprognostic (1.03e-1)" "unprognostic (2.73e-1)" "unprognostic (6.68e-2)" "potential prognostic favorable (7.74e-5)" "unprognostic (2.63e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (2.53e-4)" "unprognostic (1.85e-2)" "unprognostic (2.52e-2)" "unprognostic (9.58e-2)" "unprognostic (3.29e-2)" "unprognostic (6.30e-3)" "unprognostic (1.84e-2)" "unprognostic (1.07e-1)" "unprognostic (1.89e-2)" "unprognostic (1.22e-1)" "unprognostic (1.49e-1)" "unprognostic (2.24e-1)" "unprognostic (1.14e-2)" "unprognostic (3.79e-1)" "unprognostic (1.99e-3)" "unprognostic (1.59e-1)" "unprognostic (8.41e-2)" "unprognostic (1.19e-1)" "unprognostic (4.18e-1)" "unprognostic (1.68e-1)" "unprognostic (4.69e-2)" MIDN Stx ENSG00000167470 Midnolin Q504T8 19 1248553-1259143 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 772.5;Neutrophils: 749.2" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 772.5;Neutrophils: 749.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 11.7" "Lineage enriched" "Detected in many" 9 "granulocytes: 11.7" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042018, HPA049432" Uncertain Approved Nucleoplasm Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 27 Nucleoplasm "HPA042018: , HPA049432: " "unprognostic (3.48e-2)" "unprognostic (2.19e-1)" "unprognostic (2.88e-1)" "unprognostic (2.51e-3)" "unprognostic (3.56e-2)" "unprognostic (3.02e-1)" "unprognostic (2.45e-1)" "unprognostic (2.21e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (8.54e-3)" "unprognostic (2.70e-2)" "unprognostic (3.87e-2)" "potential prognostic unfavorable (8.43e-4)" "unprognostic (1.36e-1)" "unprognostic (2.99e-2)" "unprognostic (2.93e-2)" "unprognostic (6.33e-3)" "unprognostic (1.01e-1)" "unprognostic (1.75e-1)" "unprognostic (3.93e-1)" "unprognostic (3.79e-1)" "unprognostic (2.52e-2)" "unprognostic (3.53e-2)" "unprognostic (1.29e-1)" "unprognostic (1.81e-1)" "unprognostic (2.02e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-1)" "unprognostic (1.50e-1)" "unprognostic (2.70e-2)" MIF "GIF, GLIF" ENSG00000240972 "Macrophage migration inhibitory factor" P14174 22 23894383-23895227 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Isomerase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 786.6;Esophageal apical cells: 652.6;Extravillous trophoblasts: 637.0;Gastric chief cells: 823.4;Parietal cells: 887.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 4313577.8" "Low tissue specificity" "Detected in all" "HPA003868, CAB005284" Approved Enhanced Nucleoplasm,Cytosol "Secreted to blood" Cytokine No No 13800000 2500000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 112 Cytosol Nucleoplasm "CAB005284: , HPA003868: " "unprognostic (1.70e-2)" "unprognostic (1.62e-1)" "unprognostic (2.78e-1)" "unprognostic (5.73e-3)" "unprognostic (7.28e-2)" "unprognostic (2.11e-1)" "unprognostic (2.92e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (2.54e-2)" "unprognostic (5.68e-2)" "unprognostic (1.03e-1)" "unprognostic (1.39e-1)" "unprognostic (9.21e-3)" "potential prognostic unfavorable (5.90e-5)" "validated prognostic unfavorable (8.93e-5)" "validated prognostic unfavorable (6.75e-4)" "unprognostic (2.84e-2)" "unprognostic (2.93e-1)" "unprognostic (1.33e-1)" "unprognostic (2.78e-2)" "unprognostic (1.43e-1)" "unprognostic (2.62e-2)" "unprognostic (7.36e-2)" "unprognostic (8.19e-2)" "unprognostic (2.40e-1)" "unprognostic (1.78e-2)" "unprognostic (1.87e-1)" "unprognostic (1.41e-1)" "unprognostic (4.15e-2)" "unprognostic (8.42e-2)" MINDY1 "FAM63A, FLJ11280, MINDY-1" ENSG00000143409 "MINDY lysine 48 deubiquitinase 1" Q8N5J2 1 150996549-151008376 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 150.4;Neutrophils: 91.6;Platelets: 476.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 150.4;Platelets: 476.3" "Cell type enhanced" "Detected in many" "endothelial cell: 35.0;oligodendrocyte: 28.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 99.8;eosinophil: 56.7;neutrophil: 93.9" "Lineage enriched" "Detected in all" 8 "granulocytes: 99.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA028358, HPA061086" Supported Nucleoplasm NA NA 55000 "Cluster 21: Neutrophils - Unknown function" "Cluster 82: Salivary gland - Secretion" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "HPA028358: , HPA061086: " "unprognostic (3.65e-3)" "unprognostic (2.67e-1)" "unprognostic (3.51e-2)" "unprognostic (7.52e-2)" "unprognostic (1.44e-1)" "unprognostic (9.13e-2)" "unprognostic (4.63e-2)" "unprognostic (3.20e-2)" "unprognostic (7.81e-2)" "validated prognostic favorable (7.56e-8)" "validated prognostic favorable (4.97e-8)" "unprognostic (4.82e-2)" "unprognostic (3.55e-2)" "unprognostic (2.36e-1)" "unprognostic (2.08e-1)" "unprognostic (1.98e-3)" "unprognostic (3.41e-2)" "unprognostic (6.67e-2)" "unprognostic (2.13e-1)" "unprognostic (4.58e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (1.37e-2)" "unprognostic (1.09e-1)" "unprognostic (5.75e-2)" "unprognostic (7.11e-2)" "unprognostic (4.66e-2)" "unprognostic (2.36e-2)" "unprognostic (1.06e-1)" MINDY2 "FAM63B, KIAA1164" ENSG00000128923 "MINDY lysine 48 deubiquitinase 2" Q8NBR6 15 58771192-58861900 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 941433.6;Fallopian tube cells: 493505.5" "Group enriched" "Detected in many" "heart muscle: 194592.0;ovary: 258504.7" "HPA051103, HPA063669" Approved Enhanced Nucleoplasm No No "Cluster 20: Non-specific - DNA binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Nucleoplasm "HPA051103: , HPA063669: " "potential prognostic favorable (1.95e-4)" "unprognostic (7.09e-2)" "unprognostic (1.17e-3)" "unprognostic (7.49e-2)" "unprognostic (9.34e-2)" "unprognostic (9.35e-2)" "unprognostic (1.46e-2)" "unprognostic (2.04e-1)" "unprognostic (4.01e-2)" "potential prognostic favorable (3.22e-6)" "unprognostic (2.09e-3)" "unprognostic (1.39e-1)" "unprognostic (3.96e-2)" "unprognostic (3.58e-2)" "unprognostic (5.49e-2)" "unprognostic (2.18e-1)" "unprognostic (1.80e-1)" "unprognostic (3.57e-2)" "unprognostic (3.01e-2)" "unprognostic (6.28e-3)" "unprognostic (1.37e-2)" "unprognostic (1.16e-1)" "unprognostic (8.30e-2)" "unprognostic (2.75e-1)" "unprognostic (5.28e-2)" "unprognostic (4.46e-1)" "unprognostic (3.13e-1)" "unprognostic (4.94e-2)" "unprognostic (1.48e-1)" MINDY3 "C10orf97, CARP, DERP5, FAM188A, FLJ13397, my042" ENSG00000148481 "MINDY lysine 48 deubiquitinase 3" Q9H8M7 10 15778170-15860507 "Enzymes, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 229556.0;Pancreatic islets: 196601.3" "Low tissue specificity" "Detected in many" "HPA038400, HPA038406" Uncertain Supported "Nucleoplasm,Nuclear membrane,Microtubules,Primary cilium,Primary cilium tip,Cytosol" NA NA 11000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 55: Breast - Lactation" "Cluster 34: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 7: Non-specific - Transcription" 9 "Nucleoplasm, Nuclear membrane" "Microtubules, Primary cilium, Primary cilium tip, Cytosol" "HPA038400: , HPA038406: " "unprognostic (9.23e-2)" "unprognostic (8.05e-2)" "unprognostic (1.95e-1)" "unprognostic (1.57e-1)" "unprognostic (1.60e-2)" "unprognostic (2.54e-2)" "potential prognostic favorable (3.41e-5)" "unprognostic (1.80e-1)" "unprognostic (5.03e-2)" "potential prognostic favorable (1.20e-6)" "unprognostic (2.02e-2)" "unprognostic (2.18e-1)" "unprognostic (8.43e-2)" "unprognostic (2.02e-1)" "unprognostic (8.79e-2)" "unprognostic (5.46e-2)" "unprognostic (3.17e-1)" "unprognostic (8.01e-2)" "unprognostic (1.41e-3)" "unprognostic (7.29e-3)" "unprognostic (3.02e-2)" "unprognostic (1.08e-1)" "unprognostic (2.30e-2)" "unprognostic (4.89e-2)" "unprognostic (3.32e-1)" "unprognostic (1.58e-1)" "unprognostic (2.95e-1)" "unprognostic (3.43e-1)" "unprognostic (2.11e-2)" MIPEP MIP ENSG00000027001 "Mitochondrial intermediate peptidase" Q99797 13 23730189-23889400 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 223.7;Ependymal cells: 317.0;Respiratory ciliated cells: 306.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 317.0" "Cell type enhanced" "Detected in all" "ependymal cell: 344.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 27007748.4" "Low tissue specificity" "Detected in many" "HPA030676, HPA031669, HPA031670" Approved Enhanced Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 13 Mitochondria "HPA030676: , HPA031669: , HPA031670: " "unprognostic (1.82e-1)" "unprognostic (3.46e-2)" "unprognostic (2.89e-2)" "unprognostic (4.51e-2)" "unprognostic (1.47e-1)" "unprognostic (7.91e-2)" "unprognostic (1.25e-1)" "unprognostic (2.00e-2)" "unprognostic (4.35e-2)" "unprognostic (1.74e-1)" "potential prognostic favorable (2.64e-12)" "unprognostic (8.88e-2)" "potential prognostic favorable (4.54e-4)" "unprognostic (1.28e-1)" "unprognostic (1.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (6.46e-2)" "unprognostic (1.09e-1)" "unprognostic (1.57e-2)" "unprognostic (7.66e-2)" "unprognostic (1.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.35e-3)" "unprognostic (8.72e-3)" "unprognostic (3.14e-1)" "unprognostic (2.54e-2)" "unprognostic (2.71e-1)" "unprognostic (3.09e-1)" "unprognostic (1.69e-1)" MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 185.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 116.6;Colonocytes: 703.5;Enteric stem cells: 135.8;Enteric transient amplifying cells: 190.7;Enterocytes: 1134.4;Fallopian tube ciliated cells: 126.0;Foveolar cells: 103.8;Goblet cells: 251.5;Paneth cells: 108.3" "Cell type enriched" "Detected in many" 4 "Enterocytes: 1134.4" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 185.9;Rectum Adenocarcinoma (TCGA): 174.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 104.4" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Fallopian tube cells: 2350595.3;Proximal tubules: 6225893.6" "Group enriched" "Detected in some" "intestine: 879785.6;kidney: 1795682.3" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 77 "Plasma membrane, Focal adhesion sites" "HPA049511: , HPA062232: " "unprognostic (1.62e-2)" "unprognostic (5.85e-2)" "unprognostic (9.27e-2)" "unprognostic (1.02e-1)" "unprognostic (1.89e-1)" "unprognostic (6.83e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-1)" "unprognostic (2.24e-1)" "unprognostic (1.57e-2)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (7.58e-2)" "unprognostic (1.37e-3)" "unprognostic (1.42e-1)" "unprognostic (1.07e-2)" "unprognostic (8.40e-2)" "unprognostic (2.15e-3)" "unprognostic (3.26e-2)" "unprognostic (2.35e-1)" "unprognostic (8.03e-3)" "unprognostic (5.34e-2)" "unprognostic (6.51e-3)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" MIX23 "CCDC58, FLJ33273" ENSG00000160124 "Mitochondrial matrix import factor 23" Q4VC31 3 122359591-122383231 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 71.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 10521769.3" "Group enriched" "Detected in all" "heart muscle: 29671715.0;intestine: 44381550.1;kidney: 25275644.8;liver: 24332773.5" HPA051965 Approved Approved Nucleoli,Mitochondria No No 22000 "Cluster 30: Non-specific - DNA binding" "Cluster 76: Non-specific - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 5 Mitochondria Nucleoli "HPA051965: " "unprognostic (1.38e-1)" "unprognostic (5.17e-2)" "unprognostic (1.40e-1)" "unprognostic (3.08e-1)" "unprognostic (3.17e-2)" "unprognostic (1.04e-1)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (5.05e-4)" "potential prognostic unfavorable (1.35e-5)" "unprognostic (1.96e-1)" "unprognostic (1.62e-2)" "unprognostic (2.90e-2)" "validated prognostic unfavorable (1.32e-6)" "validated prognostic unfavorable (1.89e-4)" "potential prognostic unfavorable (3.33e-4)" "unprognostic (6.80e-3)" "unprognostic (6.26e-2)" "unprognostic (3.11e-1)" "unprognostic (2.58e-2)" "unprognostic (4.48e-2)" "validated prognostic unfavorable (5.97e-5)" "validated prognostic unfavorable (3.14e-4)" "unprognostic (4.07e-3)" "unprognostic (1.54e-1)" "unprognostic (2.78e-1)" "unprognostic (3.40e-3)" "unprognostic (6.11e-2)" "unprognostic (1.55e-1)" "unprognostic (8.51e-2)" "unprognostic (1.88e-1)" MIXL1 "MILD1, MIXL" ENSG00000185155 "Mix paired-like homeobox" Q9H2W2 1 226223618-226227060 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.2" "Group enriched" "Detected in some" 5 "Oocytes: 23.0;Plasma cells: 16.2" "Group enriched" "Detected in some" 5 "Oocytes: 23.0;Plasma cells: 16.2" "Cell type enhanced" "Detected in single" "endothelial cell: 1.1" "Cancer enriched" "Detected in some" 8 "Testicular Germ Cell Tumor (TCGA): 11.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "lymphoma: 1.7;testis cancer: 1.7" "Adipose visceral - Mesothelial cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA005662 Approved Nucleoplasm NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 35: Non-specific - DNA binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 44: Plasma cells - Antibody production & secretion" Nucleoplasm "HPA005662: " "unprognostic (1.70e-1)" "unprognostic (1.60e-2)" "unprognostic (1.68e-1)" "unprognostic (2.83e-3)" "unprognostic (1.74e-1)" "unprognostic (2.02e-1)" "unprognostic (3.08e-2)" "unprognostic (1.17e-2)" MKI67 "Ki-67, MIB-1, PPP1R105" ENSG00000148773 "Marker of proliferation Ki-67" P46013 10 128096659-128126423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 43.7;lymphoid tissue: 49.0" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 104.2;Erythrocyte progenitors: 369.6;Esophageal basal cells: 115.3;Extravillous trophoblasts: 100.0;Megakaryocyte progenitors: 312.5;Monocyte progenitors: 752.7;Neutrophil progenitors: 203.8;Plasma cells: 84.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 369.6;Megakaryocytes: 312.5;Mononuclear phagocytes: 752.7;Neutrophils: 203.8" "Cell type enriched" "Detected in single" 6 "leukocyte: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 11764827.1;Neutrophils: 20328908.8;T-cells: 5854314.7" "Tissue enriched" "Detected in some" "Stomach: 35522522.3" "CAB000058, HPA000451, HPA001164, CAB068198, CAB080228" Enhanced Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 61 "Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "CAB000058: , CAB068198: , CAB080228: , HPA000451: , HPA001164: " "unprognostic (5.51e-2)" "unprognostic (1.16e-1)" "unprognostic (3.60e-1)" "unprognostic (1.92e-1)" "unprognostic (1.37e-1)" "unprognostic (3.24e-1)" "unprognostic (5.37e-1)" "unprognostic (1.60e-1)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (5.49e-5)" "potential prognostic unfavorable (3.53e-5)" "unprognostic (1.66e-3)" "potential prognostic unfavorable (1.62e-11)" "validated prognostic unfavorable (1.29e-5)" "validated prognostic unfavorable (6.56e-7)" "validated prognostic unfavorable (5.03e-5)" "validated prognostic unfavorable (4.94e-5)" "unprognostic (1.58e-1)" "unprognostic (1.50e-1)" "unprognostic (2.12e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (5.08e-5)" "unprognostic (1.91e-2)" "unprognostic (2.14e-2)" "unprognostic (1.63e-2)" "unprognostic (1.56e-2)" "unprognostic (4.98e-2)" "unprognostic (3.22e-2)" "unprognostic (2.21e-1)" "unprognostic (1.89e-1)" "unprognostic (4.76e-1)" MKNK2 "GPRK7, MNK2" ENSG00000099875 "MAPK interacting serine/threonine kinase 2" Q9HBH9 19 2037465-2051244 "Enzymes, Predicted intracellular proteins" "Apoptosis, Translation regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1308.2" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 726.9;Esophageal suprabasal cells: 320.3;Neutrophils: 272.1;Pancreatic acinar cells: 296.4;Thymic myoid cells: 282.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 726.9" "Cell type enhanced" "Detected in all" "endothelial cell: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 445 "B-cells: 83400.2;Large ducts: 28307.7;Macrophages: 26307.5;T-cells: 40182.4" "Group enriched" "Detected in some" 722 "bone marrow: 30793.6;lymphoid tissue: 113600.6" "HPA021875, CAB037253, HPA070499" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 20: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 20: Non-specific - Transcription regulation" 7 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB037253: , HPA021875: , HPA070499: " "unprognostic (5.60e-2)" "unprognostic (1.44e-1)" "unprognostic (5.86e-2)" "unprognostic (2.21e-1)" "unprognostic (2.37e-1)" "unprognostic (1.58e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-1)" "unprognostic (5.87e-2)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "potential prognostic favorable (6.79e-4)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.13e-6)" "unprognostic (8.95e-2)" "unprognostic (7.21e-2)" "unprognostic (2.22e-2)" "unprognostic (4.29e-2)" "unprognostic (5.98e-2)" "unprognostic (1.15e-1)" "unprognostic (2.84e-1)" "unprognostic (6.23e-2)" "unprognostic (7.20e-2)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (1.94e-1)" "unprognostic (2.21e-1)" "unprognostic (2.33e-1)" "potential prognostic favorable (9.22e-4)" "unprognostic (4.25e-2)" "unprognostic (1.94e-1)" "unprognostic (4.17e-2)" MKRN1 RNF61 ENSG00000133606 "Makorin ring finger protein 1" Q9UHC7 7 140453033-140479536 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocytes: 411.5;Late primary spermatocytes: 662.7;Late spermatids: 509.7;Platelets: 409.0" "Cell type enhanced" "Detected in all" "Erythrocytes: 411.5;Platelets: 409.0;Spermatogenic cell types: 662.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Testicular Germ Cell Tumor (TCGA): 421.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 156 "Distal tubules: 7663.7;Microglia and Neuropil: 8872.2;Neurons: 30189.7" "Not detected" "Not detected" HPA000567 Approved Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 36 "Nucleoplasm, Cytosol" "HPA000567: " "unprognostic (1.92e-1)" "unprognostic (2.29e-1)" "unprognostic (2.62e-1)" "unprognostic (9.13e-2)" "unprognostic (2.34e-1)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (8.66e-2)" "unprognostic (2.21e-1)" "unprognostic (7.39e-2)" "validated prognostic favorable (4.14e-7)" "validated prognostic favorable (8.19e-4)" "unprognostic (2.24e-1)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (6.12e-2)" "unprognostic (5.18e-2)" "unprognostic (7.48e-2)" "unprognostic (1.70e-1)" "unprognostic (3.10e-2)" "potential prognostic unfavorable (6.79e-4)" "unprognostic (4.54e-2)" "unprognostic (9.36e-2)" "unprognostic (8.88e-2)" "unprognostic (1.16e-1)" "unprognostic (4.62e-2)" "unprognostic (3.97e-2)" "unprognostic (1.07e-2)" "unprognostic (3.47e-1)" "unprognostic (6.84e-2)" "unprognostic (1.29e-1)" MKRN2 "HSPC070, RNF62" ENSG00000075975 "Makorin ring finger protein 2" Q9H000 3 12557057-12586208 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 722.3;Late spermatids: 1168.5" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 1168.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "lung: 16875228.8" "HPA037559, HPA037560" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 36 "Nucleoplasm, Cytosol" "HPA037559: , HPA037560: " "unprognostic (5.57e-2)" "unprognostic (5.95e-2)" "unprognostic (4.21e-2)" "unprognostic (5.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-1)" "unprognostic (6.43e-2)" "unprognostic (1.76e-1)" "unprognostic (8.61e-2)" "unprognostic (4.68e-3)" "potential prognostic favorable (1.65e-5)" "unprognostic (2.31e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (3.06e-5)" "unprognostic (2.06e-2)" "unprognostic (1.86e-2)" "unprognostic (2.65e-2)" "unprognostic (1.47e-1)" "unprognostic (7.37e-2)" "unprognostic (9.14e-2)" "unprognostic (4.35e-2)" "unprognostic (4.67e-2)" "unprognostic (9.70e-2)" "unprognostic (2.35e-2)" "unprognostic (1.75e-2)" "unprognostic (1.22e-1)" "unprognostic (3.83e-1)" "unprognostic (2.77e-1)" "unprognostic (2.81e-2)" "unprognostic (5.85e-2)" "unprognostic (2.76e-1)" MLIP "C6orf142, CIP, MGC18257" ENSG00000146147 "Muscular LMNA interacting protein" Q5VWP3 6 53929982-54266280 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "heart muscle: 186.2;liver: 119.5;skeletal muscle: 205.1;tongue: 139.5" "Group enriched" "Detected in many" 12 "Cardiomyocytes: 2539.9;Myonuclei: 3506.9;Thymic myoid cells: 4190.4" "Group enriched" "Detected in many" 13 "Myocytes: 3506.9;Stromal cells: 4190.4" "Cell type enhanced" "Detected in many" "deep-layer corticothalamic and 6b: 459.2;miscellaneous: 429.2;upper-layer intratelencephalic: 657.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 16.9;skin cancer: 10.3" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Capillaries: 33139651.6;Cardiomyocytes: 59627295.0;Skeletal myofibers: 32192574.2" "Group enriched" "Detected in some" "heart muscle: 248927522.1;skeletal muscle: 134743003.6" "HPA029252, HPA046654, HPA077663" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 41: Striated muscle - Muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 1 "Nucleoplasm, Plasma membrane" Vesicles "HPA029252: , HPA046654: , HPA077663: " "unprognostic (3.89e-2)" "unprognostic (6.07e-3)" "potential prognostic favorable (1.68e-4)" "unprognostic (2.74e-2)" "unprognostic (1.18e-3)" "unprognostic (7.03e-2)" "unprognostic (1.81e-2)" "potential prognostic favorable (6.67e-5)" "unprognostic (7.77e-3)" "potential prognostic favorable (4.98e-5)" "unprognostic (3.26e-2)" "unprognostic (3.02e-3)" "unprognostic (2.56e-3)" "unprognostic (1.74e-1)" "unprognostic (7.83e-2)" "unprognostic (6.34e-2)" "unprognostic (5.32e-2)" "unprognostic (2.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.28e-2)" MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hofbauer cells: 37.5;Macrophages: 46.9;Monocyte progenitors: 54.3;monocytes: 69.4;Neutrophil progenitors: 74.8;Neutrophils: 118.8;Plasma cells: 58.0;Vascular endothelial cells: 69.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 69.7;Mononuclear phagocytes: 69.4;Neutrophils: 118.8" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 32.7;endothelial cell: 57.5;leukocyte: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Testis - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 1499506.8;Pancreatic islets: 1093275.0" "Tissue enhanced" "Detected in many" "blood vessel: 4509652.7" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 47: Endothelial cells - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 4 "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (1.15e-1)" "unprognostic (2.76e-1)" "potential prognostic favorable (5.44e-4)" "unprognostic (5.85e-3)" "unprognostic (1.84e-1)" "unprognostic (4.88e-2)" "unprognostic (6.53e-3)" "unprognostic (1.11e-1)" "unprognostic (4.82e-1)" "unprognostic (1.39e-1)" "unprognostic (7.01e-3)" "unprognostic (7.01e-2)" "unprognostic (1.75e-2)" "unprognostic (3.67e-2)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (7.30e-2)" "unprognostic (5.03e-2)" "unprognostic (1.29e-1)" "unprognostic (1.40e-1)" "unprognostic (1.05e-1)" "unprognostic (5.94e-2)" "potential prognostic unfavorable (3.47e-5)" "unprognostic (3.29e-1)" "unprognostic (1.37e-2)" "unprognostic (1.37e-1)" "unprognostic (2.53e-1)" "unprognostic (2.52e-1)" "unprognostic (1.52e-2)" "unprognostic (3.36e-1)" "unprognostic (4.89e-2)" MLLT11 AF1Q ENSG00000213190 "MLLT11 transcription factor 7 cofactor" Q13015 1 151060397-151069544 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 131.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 58.3;Brain inhibitory neurons: 45.9;Early spermatids: 94.2;Late spermatids: 364.6;Other brain neurons: 76.3;Smooth muscle cells: 43.3" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 364.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 79.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Neuroblastoma: 257.8" "Colon - Colon enteroendocrine cells, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 2453780.1" "Group enriched" "Detected in some" 12334 "cerebral cortex: 1326275.2;intestine: 1140611.4" HPA000540 Uncertain Supported Nucleoplasm,Cytosol No No "Cluster 24: Non-specific - Transcription" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 103: Non-specific - Basic cellular processes" 5 "Nucleoplasm, Cytosol" "HPA000540: " "unprognostic (7.41e-2)" "unprognostic (8.63e-2)" "unprognostic (2.00e-1)" "unprognostic (2.73e-2)" "unprognostic (6.41e-3)" "unprognostic (2.10e-1)" "unprognostic (9.82e-2)" "unprognostic (3.09e-3)" "unprognostic (6.87e-3)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (7.69e-9)" "unprognostic (4.69e-3)" "potential prognostic unfavorable (8.86e-7)" "unprognostic (2.35e-2)" "unprognostic (6.53e-3)" "unprognostic (1.17e-1)" "unprognostic (1.66e-1)" "unprognostic (5.90e-2)" "unprognostic (5.14e-2)" "unprognostic (7.08e-2)" "unprognostic (8.59e-2)" "unprognostic (3.58e-1)" "unprognostic (2.22e-2)" "unprognostic (8.21e-2)" "unprognostic (5.87e-2)" "unprognostic (3.46e-2)" "unprognostic (6.41e-2)" "unprognostic (3.61e-3)" "unprognostic (1.58e-1)" "unprognostic (3.20e-1)" "unprognostic (2.39e-1)" MMAA cblA ENSG00000151611 "Metabolism of cobalamin associated A" Q8IVH4 4 145599042-145660033 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Chaperone, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 22.9" "Cell type enriched" "Detected in many" 6 "Early spermatids: 299.8" "Cell type enriched" "Detected in many" 7 "Spermatogenic cell types: 299.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 19926249.9;Proximal tubules: 22431237.4" "Tissue enhanced" "Detected in many" "liver: 13171883.8" "HPA037361, HPA058187" Supported Supported Cytosol No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 2: Neurons - Nucleosome" "Cluster 55: Lymphoma - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Cytosol "HPA037361: , HPA058187: " "unprognostic (1.35e-1)" "unprognostic (9.04e-3)" "unprognostic (7.53e-2)" "unprognostic (1.32e-1)" "potential prognostic favorable (7.70e-4)" "unprognostic (2.26e-1)" "unprognostic (2.60e-1)" "unprognostic (1.54e-2)" "unprognostic (1.26e-1)" "unprognostic (3.48e-1)" "validated prognostic favorable (1.69e-10)" "validated prognostic favorable (1.34e-5)" "unprognostic (2.85e-2)" "unprognostic (1.26e-2)" "potential prognostic favorable (3.57e-9)" "unprognostic (2.13e-1)" "unprognostic (1.02e-1)" "unprognostic (4.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.11e-1)" "unprognostic (7.04e-3)" "potential prognostic unfavorable (5.15e-4)" "unprognostic (4.23e-1)" "unprognostic (2.80e-1)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (2.51e-1)" "unprognostic (3.60e-2)" "unprognostic (3.53e-1)" "unprognostic (2.87e-2)" "unprognostic (3.43e-1)" MMAB "cblB, CFAP23" ENSG00000139428 "Metabolism of cobalamin associated B" Q96EY8 12 109553715-109573580 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 105.3" "Cell type enhanced" "Detected in many" "Breast lactating cells: 202.3;Esophageal apical cells: 162.7;Hepatocytes: 220.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 43804562.0" "Tissue enhanced" "Detected in many" "liver: 21280610.3" HPA039017 Supported Approved Mitochondria NA NA 43000 "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 30: White matter - Myelination" "Cluster 35: RS4;11 - Unknown function" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 19 Mitochondria "HPA039017: " "unprognostic (2.27e-2)" "unprognostic (6.90e-3)" "unprognostic (4.06e-2)" "unprognostic (3.47e-3)" "unprognostic (1.81e-1)" "unprognostic (2.88e-1)" "unprognostic (8.90e-3)" "unprognostic (1.14e-1)" "unprognostic (2.42e-1)" "unprognostic (2.82e-2)" "unprognostic (3.40e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-3)" "unprognostic (1.55e-1)" "unprognostic (3.98e-2)" "unprognostic (2.09e-1)" "unprognostic (1.06e-2)" "unprognostic (1.55e-1)" "unprognostic (6.61e-2)" "unprognostic (4.11e-1)" "unprognostic (1.78e-2)" "unprognostic (2.17e-2)" "unprognostic (8.60e-2)" "unprognostic (2.07e-1)" "unprognostic (8.57e-2)" "unprognostic (2.05e-1)" "unprognostic (4.25e-2)" "unprognostic (1.17e-1)" "unprognostic (1.93e-1)" "unprognostic (7.31e-2)" "unprognostic (3.36e-2)" MMD "MMA, PAQR11" ENSG00000108960 "Monocyte to macrophage differentiation associated" Q15546 17 55392622-55421924 "Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 142.9;brain: 101.7" "Cell type enriched" "Detected in many" 11 "Platelets: 2538.3" "Cell type enriched" "Detected in many" 11 "Platelets: 2538.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA026978 Approved Vesicles NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 47: Platelets - Hemostasis" 19 Vesicles "HPA026978: " "unprognostic (9.40e-2)" "unprognostic (1.68e-1)" "unprognostic (1.84e-1)" "unprognostic (4.34e-2)" "unprognostic (2.13e-2)" "unprognostic (1.06e-1)" "unprognostic (8.53e-2)" "unprognostic (3.45e-3)" "unprognostic (3.89e-2)" "unprognostic (1.95e-3)" "potential prognostic favorable (6.84e-4)" "unprognostic (2.02e-2)" "potential prognostic unfavorable (1.24e-6)" "validated prognostic unfavorable (9.76e-5)" "validated prognostic unfavorable (2.47e-5)" "unprognostic (3.76e-3)" "unprognostic (3.38e-2)" "unprognostic (1.30e-1)" "unprognostic (6.05e-2)" "unprognostic (5.52e-2)" "unprognostic (1.62e-2)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (7.42e-5)" "potential prognostic unfavorable (8.27e-5)" "unprognostic (5.08e-1)" "unprognostic (2.03e-3)" "unprognostic (1.40e-1)" "unprognostic (6.22e-3)" "unprognostic (3.70e-2)" "unprognostic (1.54e-2)" "unprognostic (1.89e-1)" MME "CALLA, CD10, NEP" ENSG00000196549 "Membrane metalloendopeptidase" P08473 3 155024124-155183704 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, FDA approved drug targets, Neurodegeneration, Neuropathy, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 314.1;kidney: 282.6" "Cell type enhanced" "Detected in many" "Adipocytes: 329.8;Basal prostatic cells: 283.8;Breast myoepithelial cells: 274.7;Endometrial stromal cells: 456.0;Enterocytes: 898.7;Fibro-adipogenic progenitors: 274.6;Neutrophils: 1431.5;Podocytes: 2387.7;Prostatic glandular cells: 346.5;Proximal tubule cells: 929.1;Thymocytes: 293.9" "Cell type enhanced" "Detected in many" "Enterocytes: 898.7;Neutrophils: 1431.5;Renal nephron cells: 2387.7" "Group enriched" "Detected in many" 7 "lower rhombic lip: 200.6;medium spiny neuron: 247.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "basal ganglia: 37.9" "Immune cell enriched" "Detected in some" 123 "neutrophil: 139.9" "Lineage enriched" "Detected in many" 123 "granulocytes: 139.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Kidney - Podocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Region enhanced" "Detected in many" "basal ganglia: 28.1" "Region enhanced" "Detected in all" "basal ganglia: 43.8" "Group enriched" "Detected in many" "Glomeruli: 1015433470.2;Proximal tubules: 604723299.0" "Tissue enriched" "Detected in many" "kidney: 393497683.9" "CAB000013, HPA052583, HPA056072" Enhanced Approved "Plasma membrane,Centrosome,Basal body,Cytosol" NA NA 470000 "Cluster 35: Neutrophils - Protein binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 "Plasma membrane, Centrosome, Basal body" Cytosol "CAB000013: , HPA052583: , HPA056072: " "unprognostic (2.30e-1)" "unprognostic (2.49e-1)" "unprognostic (5.64e-2)" "unprognostic (5.09e-3)" "unprognostic (8.46e-2)" "unprognostic (2.60e-2)" "unprognostic (3.20e-2)" "unprognostic (1.01e-2)" "unprognostic (1.31e-2)" "potential prognostic favorable (3.40e-4)" "unprognostic (2.64e-2)" "unprognostic (2.59e-2)" "unprognostic (1.41e-1)" "unprognostic (2.37e-2)" "unprognostic (3.78e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.61e-4)" "unprognostic (1.59e-1)" "unprognostic (1.64e-1)" "unprognostic (9.93e-2)" "unprognostic (6.95e-3)" "unprognostic (1.39e-2)" "unprognostic (1.07e-1)" "unprognostic (6.95e-2)" "unprognostic (1.87e-1)" "unprognostic (2.21e-1)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (3.37e-3)" "unprognostic (3.65e-2)" MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 34 "endometrium 1: 249.7" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 142.7;Endometrial secretory cells: 628.4;Ocular epithelial cells: 411.7;Respiratory basal cells: 174.5" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 411.7;Basal cells: 174.5;Goblet cells: 142.7;Secretory cells: 628.4" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 85.8;Head and Neck Squamous Cell Carcinoma (TCGA): 152.9;Lung Squamous Cell Carcinoma (TCGA): 122.0" "Region enhanced" "Detected in some" "thalamus: 3.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "head and neck cancer: 33.9;Rhabdoid: 128.8;Sarcoma: 41.0" "Not detected" "Not detected" "Not detected" "Not detected" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Enzyme NA NA "Cluster 75: Ovary - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 7 Cytosol "Plasma membrane" "CAB002159: " "unprognostic (2.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.10e-1)" "unprognostic (2.15e-1)" "unprognostic (3.72e-2)" "unprognostic (1.67e-1)" "unprognostic (2.90e-2)" "unprognostic (1.62e-1)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (1.32e-2)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (9.12e-2)" "unprognostic (4.05e-1)" "unprognostic (5.74e-2)" "unprognostic (1.39e-2)" "unprognostic (1.55e-3)" "unprognostic (3.99e-1)" "unprognostic (6.23e-2)" "unprognostic (1.31e-2)" "unprognostic (2.52e-1)" "unprognostic (4.43e-2)" "unprognostic (3.50e-1)" MMP14 MT1-MMP ENSG00000157227 "Matrix metallopeptidase 14" P50281 14 22836560-22849041 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes, Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 121.7;Decidual stromal cells: 198.3;Extravillous trophoblasts: 375.3;Fibroblasts: 127.1;Hofbauer cells: 102.2;Migrating cytotrophoblasts: 127.8;Syncytiotrophoblasts: 131.0" "Cell type enhanced" "Detected in many" "Stromal cells: 198.3;Trophoblast cells: 375.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 25.9;choroid plexus epithelial cell: 59.8;fibroblast: 38.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "choroid plexus: 126.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 882105.4;Keratinocytes: 881962.8" "Tissue enhanced" "Detected in many" "ovary: 7324128.2" "CAB009918, HPA051432" Approved Approved "Intermediate filaments,Cytosol" No No 630000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 36 Cytosol "Intermediate filaments" "CAB009918: , HPA051432: " "unprognostic (3.28e-1)" "unprognostic (2.05e-1)" "unprognostic (9.42e-2)" "unprognostic (9.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.84e-2)" "unprognostic (5.94e-2)" "unprognostic (1.91e-2)" "unprognostic (2.15e-2)" "unprognostic (5.32e-2)" "unprognostic (6.79e-2)" "unprognostic (1.89e-3)" "unprognostic (1.76e-1)" "unprognostic (2.56e-3)" "unprognostic (7.45e-2)" "unprognostic (3.87e-3)" "potential prognostic unfavorable (2.56e-5)" "unprognostic (1.75e-1)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (2.09e-3)" "unprognostic (1.08e-2)" "unprognostic (4.61e-2)" "unprognostic (4.33e-2)" "unprognostic (7.78e-2)" "unprognostic (1.57e-3)" "unprognostic (9.46e-2)" "unprognostic (4.49e-2)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (8.64e-2)" MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 67.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "upper rhombic lip: 194.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 39.4" "Region enriched" "Detected in all" 4 "cerebellum: 88.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 30.5;Kidney cancer: 41.0" "Adipose visceral - Mesothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 68.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" "Cell adhesion" Yes No "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 2: Cerebellar granular cells - Neuronal signaling" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (3.73e-2)" "unprognostic (5.61e-2)" "unprognostic (9.50e-2)" "unprognostic (8.41e-2)" "unprognostic (1.66e-2)" "unprognostic (2.49e-2)" "unprognostic (2.70e-3)" "potential prognostic favorable (9.37e-9)" "unprognostic (1.71e-3)" "unprognostic (5.26e-3)" "unprognostic (1.05e-1)" "unprognostic (3.07e-2)" "unprognostic (2.23e-2)" "unprognostic (3.87e-1)" "unprognostic (1.16e-1)" "unprognostic (2.91e-1)" "unprognostic (4.79e-2)" "unprognostic (5.78e-2)" "unprognostic (6.95e-3)" "unprognostic (3.91e-1)" "unprognostic (1.90e-2)" "unprognostic (1.97e-1)" "unprognostic (1.66e-2)" "unprognostic (3.77e-2)" "unprognostic (8.96e-2)" "unprognostic (1.62e-1)" MNAT1 "MAT1, RNF66" ENSG00000020426 "MNAT1 component of CDK activating kinase" P51948 14 60734742-60969965 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 593.1" "Cell type enhanced" "Detected in all" "Myocytes: 593.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 4642102.1;T-cells: 4557524.7" "Tissue enriched" "Detected in some" "lymphoid tissue: 146166.3" "HPA000701, HPA001154, CAB004495" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 47 Nucleoplasm "CAB004495: , HPA000701: , HPA001154: " "unprognostic (3.96e-2)" "unprognostic (3.22e-1)" "unprognostic (1.95e-1)" "unprognostic (9.92e-3)" "unprognostic (1.59e-1)" "unprognostic (3.06e-3)" "unprognostic (4.62e-2)" "potential prognostic favorable (1.92e-4)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (1.34e-1)" "potential prognostic favorable (3.72e-4)" "unprognostic (9.98e-3)" "unprognostic (1.92e-1)" "unprognostic (1.14e-2)" "unprognostic (8.05e-2)" "unprognostic (1.63e-3)" "unprognostic (1.77e-1)" "unprognostic (5.63e-2)" "unprognostic (9.25e-2)" "unprognostic (7.67e-2)" "unprognostic (9.12e-3)" "unprognostic (3.64e-2)" "potential prognostic unfavorable (5.94e-4)" "unprognostic (8.32e-2)" "unprognostic (1.09e-1)" "unprognostic (3.46e-1)" "unprognostic (6.90e-2)" "unprognostic (9.49e-2)" "unprognostic (1.16e-1)" "unprognostic (9.12e-2)" "unprognostic (9.13e-3)" MNDA PYHIN3 ENSG00000163563 "Myeloid cell nuclear differentiation antigen" P41218 1 158831351-158849506 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 276.9;lymphoid tissue: 101.5" "Cell type enhanced" "Detected in some" "cDC: 323.6;Monocyte progenitors: 1201.1;monocytes: 851.3;Neutrophil progenitors: 2911.0;Neutrophils: 4000.3" "Group enriched" "Detected in many" 8 "Mononuclear phagocytes: 1201.1;Neutrophils: 4000.3" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 159.8;pericyte: 70.3;vascular associated smooth muscle cell: 96.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 6034.1" "Lineage enriched" "Detected in all" 4 "granulocytes: 6034.1" "Group enriched" "Detected in some" 20 "Leukemia: 41.4;lymphoma: 11.9" "Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neutrophils: 206817230.4" "Group enriched" "Detected in many" "bone marrow: 55203676.3;lymphoid tissue: 35822243.1" "HPA034532, HPA073215" Enhanced Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Vesicles,Cytosol" NA NA 570000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 22 Nucleoplasm "Nucleoli, Nucleoli rim, Vesicles, Cytosol" "HPA034532: , HPA073215: " "unprognostic (7.16e-2)" "unprognostic (5.02e-2)" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" "unprognostic (2.27e-1)" "unprognostic (1.46e-1)" "unprognostic (3.75e-2)" "unprognostic (7.40e-2)" "unprognostic (1.65e-2)" "unprognostic (4.97e-1)" "unprognostic (2.87e-3)" "unprognostic (2.39e-1)" "unprognostic (1.67e-1)" "unprognostic (1.38e-2)" "unprognostic (2.86e-1)" "unprognostic (2.48e-3)" "unprognostic (4.40e-2)" "unprognostic (2.73e-1)" "unprognostic (1.17e-1)" "unprognostic (5.08e-1)" "unprognostic (2.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.28e-1)" "unprognostic (9.13e-2)" "unprognostic (7.74e-2)" "unprognostic (1.06e-1)" "unprognostic (4.94e-2)" "unprognostic (9.93e-2)" "unprognostic (4.22e-2)" "unprognostic (2.72e-2)" "unprognostic (2.11e-1)" MNX1 "HB9, HLXB9, HOXHB9, SCRA1" ENSG00000130675 "Motor neuron and pancreas homeobox 1" P50219 7 156994051-157010663 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "intestine: 6.8;pancreas: 15.3" "Cell type enhanced" "Detected in some" "Colonocytes: 20.5;Corticotrophs: 85.8;Enteric stem cells: 26.5;Enteric transient amplifying cells: 22.4;Goblet cells: 40.2;Neuroendocrine cells: 46.1;Pancreatic duct cells: 77.1;Pancreatic islet cells: 53.8;Paneth cells: 42.5;Tuft cells: 34.6" "Cell type enhanced" "Detected in many" "Ductal cells: 77.1;Enteroendocrine cells: 46.1;Goblet cells: 40.2;Pancreatic islet cells: 53.8;Pituitary endocrine cells: 85.8;Secretory gland support: 42.5" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 1.5;upper rhombic lip: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Pituitary gland - Corticotropes" "Not detected" "Not detected" "Region enriched" "Detected in single" 41 "spinal cord: 4.1" "Cell type enriched" "Detected in single" 1735 "Pancreatic islets: 173483.9" "Not detected" "Not detected" HPA071717 Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 8: Pancreas - Proteolysis" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 2 Nucleoplasm "Nucleoli, Cytosol" "HPA071717: " "unprognostic (1.39e-1)" "unprognostic (1.24e-1)" "unprognostic (3.39e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-2)" "unprognostic (2.89e-2)" "unprognostic (4.97e-2)" "unprognostic (4.08e-1)" "unprognostic (3.65e-3)" "unprognostic (1.01e-1)" "unprognostic (1.37e-2)" "unprognostic (7.45e-2)" "unprognostic (1.83e-2)" "unprognostic (6.81e-2)" "unprognostic (1.27e-1)" "unprognostic (1.87e-1)" "unprognostic (2.36e-1)" "unprognostic (3.88e-2)" "unprognostic (4.85e-2)" "unprognostic (2.56e-1)" MOCS1 MOCOD ENSG00000124615 "Molybdenum cofactor synthesis 1" Q9NZB8 6 39899578-39934551 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Molybdenum cofactor biosynthesis" Lyase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 91.9;Cardiomyocytes: 28.4;Cytotrophoblasts: 46.2;Epicardial cells: 43.2;Hepatocytes: 48.9;Pericytes: 92.9;Vascular smooth muscle cells: 37.8" "Cell type enhanced" "Detected in many" "Adipocytes: 91.9;Mural cells: 92.9" "Cell type enhanced" "Detected in all" "pericyte: 49.1;vascular associated smooth muscle cell: 39.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43129616.9" "Group enriched" "Detected in many" "cerebral cortex: 396483.4;heart muscle: 938929.3;Stomach: 630718.5" "HPA045783, HPA058177, HPA075505" Uncertain Enhanced Cytosol NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "HPA045783: , HPA058177: , HPA075505: " "unprognostic (1.87e-1)" "unprognostic (1.50e-1)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (3.97e-5)" "unprognostic (2.09e-1)" "unprognostic (9.61e-2)" "unprognostic (1.29e-1)" "unprognostic (9.96e-2)" "unprognostic (1.11e-1)" "unprognostic (2.09e-1)" "unprognostic (1.45e-3)" "unprognostic (6.56e-3)" "unprognostic (2.29e-2)" "unprognostic (6.97e-2)" "unprognostic (5.72e-2)" "potential prognostic favorable (7.29e-4)" "unprognostic (1.19e-1)" "unprognostic (2.17e-2)" "unprognostic (5.27e-2)" "unprognostic (4.70e-2)" "unprognostic (2.49e-1)" "unprognostic (2.58e-3)" "unprognostic (9.66e-2)" "unprognostic (2.58e-2)" "unprognostic (3.48e-1)" "unprognostic (9.05e-2)" "unprognostic (1.41e-1)" "unprognostic (2.57e-3)" "unprognostic (2.11e-1)" "unprognostic (6.25e-2)" "unprognostic (6.27e-2)" MORC4 "FLJ11565, ZCW4, ZCWCC2" ENSG00000133131 "MORC family CW-type zinc finger 4" Q8TE76 X 106813871-107000212 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 74.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 500.6;Migrating cytotrophoblasts: 248.0;Pancreatic duct cells: 133.1;Syncytiotrophoblasts: 325.4" "Cell type enhanced" "Detected in many" "Trophoblast cells: 500.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1458 "Oocytes: 145795.3" "Not detected" "Not detected" "HPA000395, HPA015547, HPA050250" Enhanced Enhanced Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 6 Nucleoplasm "HPA000395: , HPA015547: , HPA050250: " "unprognostic (3.49e-1)" "potential prognostic unfavorable (2.09e-4)" "unprognostic (7.89e-2)" "unprognostic (1.27e-2)" "unprognostic (1.49e-3)" "unprognostic (3.78e-1)" "unprognostic (3.70e-1)" "unprognostic (2.94e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (3.41e-2)" "unprognostic (7.88e-2)" "unprognostic (2.00e-2)" "unprognostic (2.43e-1)" "unprognostic (3.43e-1)" "unprognostic (2.80e-1)" "unprognostic (3.49e-2)" "unprognostic (7.06e-2)" "unprognostic (2.98e-2)" "unprognostic (6.94e-2)" "unprognostic (2.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.03e-1)" "unprognostic (1.36e-1)" "unprognostic (5.43e-3)" "unprognostic (6.34e-3)" "unprognostic (1.19e-1)" "unprognostic (2.15e-1)" "unprognostic (4.53e-2)" "unprognostic (4.39e-1)" "unprognostic (1.89e-1)" MOXD1 "dJ248E1.1, DKFZP564G202, MOX" ENSG00000079931 "Monooxygenase DBH like 1" Q6UVY6 6 132296055-132401475 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 59.9;smooth muscle: 73.5" "Cell type enhanced" "Detected in many" "Astrocytes: 73.2;Decidual stromal cells: 132.8;Early spermatids: 127.8;Endometrial stromal cells: 95.5;Esophageal basal cells: 92.9;Fibroblasts: 70.0;Müller glia: 46.7;Pituicytes/FSCs: 262.4;Salivary myoepithelial cells: 130.5" "Cell type enhanced" "Detected in many" "Basal cells: 92.9;Glial cells: 262.4;Secretory gland support: 130.5;Spermatogenic cell types: 127.8;Stromal cells: 132.8" "Cell type enhanced" "Detected in many" "amygdala excitatory: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "memory B-cell: 3.1;naive B-cell: 1.7;plasmacytoid DC: 5.1" "Group enriched" "Detected in many" 41 "B-cells: 3.1;dendritic cells: 5.1" "Cancer enhanced" "Detected in many" "skin cancer: 61.1" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 2812987.5;Collecting ducts: 2194941.5;Microglia and Neuropil: 3213070.5;Neurons: 1053736.8" "Tissue enhanced" "Detected in many" "skin: 8559322.2" HPA035740 Approved Approved Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 5 Cytosol "HPA035740: " "unprognostic (1.41e-2)" "unprognostic (1.14e-1)" "unprognostic (2.39e-1)" "unprognostic (3.04e-2)" "unprognostic (5.83e-2)" "unprognostic (1.56e-1)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (1.01e-5)" "potential prognostic favorable (3.75e-4)" "unprognostic (5.42e-2)" "unprognostic (9.01e-2)" "unprognostic (2.41e-3)" "unprognostic (2.06e-3)" "unprognostic (1.01e-1)" "unprognostic (2.66e-2)" "unprognostic (1.33e-1)" "unprognostic (1.97e-1)" "unprognostic (4.23e-2)" "unprognostic (6.60e-3)" "unprognostic (4.68e-2)" "potential prognostic unfavorable (2.33e-5)" "unprognostic (1.61e-1)" "unprognostic (1.39e-1)" "unprognostic (7.59e-2)" "unprognostic (1.71e-1)" "unprognostic (7.09e-3)" "unprognostic (6.99e-2)" "unprognostic (1.06e-3)" "unprognostic (5.33e-2)" "unprognostic (6.94e-2)" "unprognostic (9.07e-2)" MPC1 "BRP44L, CGI-129, dJ68L15.3, SLC54A1" ENSG00000060762 "Mitochondrial pyruvate carrier 1" Q9Y5U8 6 166364919-166383013 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 692.4;tongue: 521.3" "Cell type enhanced" "Detected in all" "Epididymal clear cells: 481.8;Hepatocytes: 480.3;Parietal cells: 1069.6" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 1069.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enhanced" "Detected in many" "liver: 7952385.3" "HPA045119, HPA055790" Enhanced Enhanced "Mitochondria,Principal piece" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 3 Mitochondria "Principal piece" "HPA045119: , HPA055790: " "unprognostic (2.16e-1)" "potential prognostic unfavorable (4.03e-4)" "unprognostic (2.68e-3)" "unprognostic (1.26e-2)" "unprognostic (2.08e-1)" "unprognostic (2.53e-2)" "unprognostic (1.76e-3)" "unprognostic (6.92e-2)" "unprognostic (2.24e-1)" "potential prognostic favorable (1.71e-7)" "unprognostic (2.59e-3)" "potential prognostic favorable (2.35e-4)" "unprognostic (5.25e-2)" "unprognostic (3.74e-3)" "unprognostic (1.13e-2)" "unprognostic (1.27e-1)" "unprognostic (4.95e-2)" "unprognostic (6.59e-2)" "unprognostic (1.63e-1)" "unprognostic (2.96e-3)" "unprognostic (9.79e-2)" "unprognostic (1.66e-2)" "unprognostic (1.69e-1)" "unprognostic (1.29e-1)" "unprognostic (2.77e-1)" "unprognostic (4.96e-2)" "unprognostic (8.75e-2)" "unprognostic (3.56e-2)" "unprognostic (6.46e-2)" MPHOSPH10 "CT90, MPP10, MPP10P, PPP1R106" ENSG00000124383 "M-phase phosphoprotein 10" O00566 2 71130310-71150101 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 3740447.0;T-cells: 3527209.8" "Group enriched" "Detected in many" "intestine: 3102137.8;lymphoid tissue: 1017630.5" "HPA035059, HPA035060, HPA049907" Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 79 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA035059: , HPA035060: , HPA049907: " "unprognostic (2.95e-1)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (2.12e-1)" "unprognostic (4.02e-2)" "unprognostic (7.02e-3)" "unprognostic (1.07e-1)" "unprognostic (1.00e-1)" "unprognostic (4.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.01e-2)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (2.20e-3)" "unprognostic (4.26e-3)" "unprognostic (2.38e-2)" "unprognostic (4.38e-2)" "unprognostic (3.98e-2)" "unprognostic (4.88e-2)" "unprognostic (2.14e-1)" "unprognostic (3.23e-2)" "unprognostic (4.00e-2)" "unprognostic (9.02e-3)" "unprognostic (4.61e-2)" "unprognostic (1.69e-1)" "unprognostic (4.67e-2)" "unprognostic (1.36e-2)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (9.30e-2)" "unprognostic (1.71e-1)" MPHOSPH6 MPP6 ENSG00000135698 "M-phase phosphoprotein 6" Q99547 16 82147798-82170224 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast lactating cells: 186.0" "Cell type enhanced" "Detected in all" "Secretory cells: 186.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 2339117.5" "Tissue enriched" "Detected in many" "bone marrow: 21086444.9" "CAB003674, HPA026948" Approved Supported Nucleoplasm,Nucleoli No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 49 "Nucleoplasm, Nucleoli" "CAB003674: , HPA026948: " "unprognostic (5.29e-2)" "unprognostic (1.08e-3)" "unprognostic (3.29e-1)" "unprognostic (2.73e-2)" "unprognostic (1.74e-1)" "unprognostic (2.70e-1)" "unprognostic (6.91e-2)" "unprognostic (5.19e-2)" "unprognostic (4.09e-3)" "unprognostic (9.91e-3)" "unprognostic (6.34e-3)" "unprognostic (1.73e-2)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (7.10e-7)" "unprognostic (8.68e-3)" "unprognostic (3.68e-2)" "unprognostic (1.92e-2)" "unprognostic (6.10e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (5.55e-4)" "unprognostic (4.73e-2)" "unprognostic (3.66e-2)" "potential prognostic unfavorable (1.70e-6)" "potential prognostic unfavorable (6.41e-4)" "unprognostic (6.74e-2)" "unprognostic (2.77e-2)" "unprognostic (5.95e-2)" "unprognostic (3.18e-1)" "unprognostic (1.62e-1)" "unprognostic (3.70e-1)" "unprognostic (2.58e-1)" MPND FLJ14981 ENSG00000008382 "MPN domain containing" Q8N594 19 4343527-4360086 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 70.9;Enterocytes: 50.1;Megakaryocytes: 49.5" "Cell type enhanced" "Detected in many" "Enterocytes: 70.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 880157.8" "Not detected" "Not detected" "HPA043274, HPA045475" Approved Approved "Nucleoplasm,Nucleoli rim" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 37: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 15 "Nucleoli rim" Nucleoplasm "HPA043274: , HPA045475: " "unprognostic (2.50e-3)" "unprognostic (1.55e-2)" "unprognostic (5.86e-2)" "unprognostic (1.34e-2)" "unprognostic (2.09e-1)" "unprognostic (5.30e-2)" "unprognostic (1.50e-1)" "unprognostic (5.53e-2)" "unprognostic (1.60e-2)" "unprognostic (5.03e-3)" "potential prognostic favorable (7.56e-4)" "unprognostic (2.38e-1)" "potential prognostic favorable (1.76e-6)" "unprognostic (9.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.34e-2)" "unprognostic (4.53e-1)" "unprognostic (3.03e-2)" "unprognostic (3.80e-2)" "unprognostic (1.49e-1)" "unprognostic (6.41e-3)" "unprognostic (1.52e-1)" "unprognostic (5.36e-2)" "unprognostic (7.55e-2)" "unprognostic (1.29e-1)" "unprognostic (2.19e-1)" "unprognostic (3.25e-1)" "potential prognostic favorable (4.11e-4)" "unprognostic (1.22e-1)" "unprognostic (6.19e-1)" "unprognostic (6.68e-3)" MPO ENSG00000005381 Myeloperoxidase P05164 17 58269855-58280935 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrogen peroxide" "Oxidoreductase, Peroxidase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 158 "bone marrow: 3249.5" "Group enriched" "Detected in some" 61 "Monocyte progenitors: 2629.0;Neutrophil progenitors: 2271.8" "Group enriched" "Detected in some" 61 "Mononuclear phagocytes: 2629.0;Neutrophils: 2271.8" "Cell type enhanced" "Detected in some" "leukocyte: 2.5" "Cancer enhanced" "Detected in single" "Stomach Adenocarcinoma (TCGA): 2.0" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.2" "Low lineage specificity" "Detected in single" "Cancer enriched" "Detected in some" 776 "Leukemia: 854.7" "Lung - Neutrophils_1, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Spleen - Neutrophils_1" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in many" "Neutrophils: 3178365350.9" "Group enriched" "Detected in all" "bone marrow: 5955208536.8;lymphoid tissue: 1642950901.7" "CAB000059, HPA021147, HPA061464, CAB080352, CAB080353, CAB080354" Enhanced Supported Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme No NA 81000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 Vesicles Nucleoplasm "CAB000059: , CAB080352: , CAB080353: , CAB080354: , HPA021147: , HPA061464: " "potential prognostic unfavorable (7.87e-4)" MPP1 "DXS552E, PEMP" ENSG00000130830 "MAGUK p55 scaffold protein 1" Q00013 X 154778684-154821007 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 110.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 528.4;Erythrocyte progenitors: 184.6;Erythrocytes: 305.6;Hofbauer cells: 412.4;Megakaryocytes: 463.6;Migrating cytotrophoblasts: 211.1;Neutrophils: 297.6;Platelets: 1825.7;Syncytiotrophoblasts: 518.1" "Cell type enhanced" "Detected in many" "Megakaryocytes: 463.6;Mononuclear phagocytes: 412.4;Platelets: 1825.7;Trophoblast cells: 528.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 216.2;neutrophil: 203.0" "Group enriched" "Detected in all" 8 "dendritic cells: 57.8;granulocytes: 216.2;monocytes: 99.4" "Cancer enhanced" "Detected in many" "Leukemia: 109.3" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Lung - Neutrophils_2, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 33624819.5" "Tissue enhanced" "Detected in all" "bone marrow: 99511560.4" HPA076675 Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 370000 "Cluster 7: Non-specific - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 28 "Plasma membrane" "Centriolar satellite" "HPA076675: " "unprognostic (7.40e-2)" "unprognostic (6.25e-2)" "unprognostic (3.47e-1)" "unprognostic (9.64e-2)" "unprognostic (9.94e-2)" "unprognostic (2.23e-1)" "unprognostic (8.35e-2)" "unprognostic (2.52e-1)" "unprognostic (3.34e-3)" "unprognostic (1.78e-1)" "potential prognostic favorable (1.82e-9)" "unprognostic (7.18e-2)" "unprognostic (7.43e-2)" "unprognostic (6.94e-2)" "unprognostic (1.55e-1)" "unprognostic (8.79e-2)" "unprognostic (2.64e-2)" "unprognostic (1.96e-1)" "unprognostic (1.93e-1)" "unprognostic (2.18e-3)" "unprognostic (3.47e-2)" "unprognostic (7.24e-3)" "unprognostic (6.33e-2)" "unprognostic (2.40e-2)" "unprognostic (5.65e-2)" "unprognostic (9.04e-2)" "unprognostic (2.58e-1)" "unprognostic (1.51e-1)" "unprognostic (1.85e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" MPP4 DLG6 ENSG00000082126 "MAGUK p55 scaffold protein 4" Q96JB8 2 201644870-201698694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 175 "retina: 265.2" "Group enriched" "Detected in some" 37 "Cone photoreceptor cells: 1343.5;Rod photoreceptor cells: 930.4" "Cell type enriched" "Detected in many" 74 "Neuronal cells: 1343.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 7.8;Sarcoma: 8.8" "Testis - Late spermatids" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "cerebellum: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" HPA057393 Supported "Actin filaments,Cytosol" No No "Cluster 42: Retina - Visual perception" "Cluster 35: Non-specific - DNA binding" "Cluster 72: Neuronal - Signal transduction" "Cluster 79: Photoreceptor cells - Phototransduction" 2 Cytosol "Actin filaments" "HPA057393: " "unprognostic (4.54e-1)" "unprognostic (7.56e-3)" MPP7 FLJ32798 ENSG00000150054 "MAGUK p55 scaffold protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 34.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 381.2;Lymphatic endothelial cells: 424.1;Neutrophil progenitors: 655.5;Neutrophils: 609.7;Renal collecting duct intercalated cells: 408.4" "Cell type enhanced" "Detected in all" "Neutrophils: 655.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 9824003.1" "Tissue enriched" "Detected in many" "intestine: 17997354.7" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 27 "Cell Junctions" Nucleoplasm "HPA037597: , HPA037598: " "unprognostic (8.65e-2)" "unprognostic (1.79e-1)" "unprognostic (2.48e-1)" "unprognostic (1.45e-1)" "unprognostic (7.48e-2)" "potential prognostic favorable (3.01e-4)" "unprognostic (1.80e-1)" "unprognostic (7.99e-2)" "unprognostic (2.21e-2)" "potential prognostic favorable (7.31e-8)" "unprognostic (4.01e-2)" "unprognostic (1.02e-1)" "unprognostic (1.43e-3)" "unprognostic (4.27e-2)" "unprognostic (3.45e-3)" "unprognostic (1.63e-2)" "unprognostic (6.67e-2)" "unprognostic (2.78e-1)" "unprognostic (1.41e-1)" "unprognostic (3.31e-2)" "unprognostic (9.31e-2)" "unprognostic (2.82e-1)" "unprognostic (2.46e-1)" "unprognostic (5.89e-3)" "unprognostic (7.93e-2)" "unprognostic (2.48e-1)" "unprognostic (6.09e-2)" "unprognostic (4.08e-2)" MPPED2 "239FB, C11orf8, D11S302E, dJ1024C24.1, dJ873F21.1, FAM1B, Hs.46638" ENSG00000066382 "Metallophosphoesterase domain containing 2" Q15777 11 30384493-30586872 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 23.0;thyroid gland: 23.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 536.9;Cone photoreceptor cells: 621.0;Kupffer cells: 401.8;Oligodendrocyte progenitor cells: 459.1;Pituitary stem cells: 1422.7;Prostatic glandular cells: 843.4;Prostatic hillock cells: 398.1;Renal collecting duct intercalated cells: 1167.8;Renal collecting duct principal cells: 582.9;Renal connecting tubule cells: 777.8" "Cell type enhanced" "Detected in many" "Ductal cells: 1167.8;Glandular cells: 843.4;Stem cells: 1422.7" "Cell type enhanced" "Detected in all" "pericyte: 819.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "MAIT T-cell: 1.8" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Rhabdoid: 8.1" "Pituitary gland - Thyrotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 20278 "Granulosa cells: 2027803.7" "Group enriched" "Detected in some" "fallopian tube: 1359882.1;kidney: 593827.3" HPA062575 Approved Nucleoli,Vesicles,Mitochondria NA NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 24: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 12 Nucleoli "Vesicles, Mitochondria" "HPA062575: " "unprognostic (3.02e-2)" "unprognostic (3.77e-2)" "unprognostic (4.71e-2)" "unprognostic (4.97e-3)" "unprognostic (3.59e-2)" "unprognostic (6.01e-2)" "unprognostic (2.07e-3)" "unprognostic (4.14e-2)" "unprognostic (7.97e-3)" "validated prognostic favorable (1.69e-8)" "validated prognostic favorable (9.59e-4)" "unprognostic (4.89e-3)" "unprognostic (1.08e-1)" "unprognostic (2.71e-2)" "unprognostic (5.55e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (7.19e-4)" "unprognostic (8.75e-2)" "unprognostic (9.75e-2)" "unprognostic (2.01e-2)" "unprognostic (4.05e-3)" "unprognostic (1.50e-1)" "unprognostic (2.58e-2)" "unprognostic (3.16e-1)" MPST "MST, TST2, TUM1" ENSG00000128309 "Mercaptopyruvate sulfurtransferase" P25325 22 37019635-37029821 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 370.6" "Cell type enhanced" "Detected in many" "Colonocytes: 517.0;Enteric stem cells: 312.8;Enteric transient amplifying cells: 379.8;Enterocytes: 1169.7;Esophageal apical cells: 675.2;Esophageal suprabasal cells: 348.4;Hepatocytes: 650.0;Paneth cells: 313.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 675.2;Enterocytes: 1169.7;Hepatocytes: 650.0" "Cell type enhanced" "Detected in many" "Bergmann glia: 37.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 224541692.0" "Tissue enhanced" "Detected in all" "liver: 488931502.2" HPA001240 Enhanced Approved Mitochondria,Cytosol NA NA 3600000 "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 25: Non-specific - Ribosome" "Cluster 1: Enterocytes - Absorption and Digestion" 2 Mitochondria Cytosol "HPA001240: " "unprognostic (1.25e-1)" "unprognostic (1.15e-2)" "unprognostic (4.05e-2)" "unprognostic (9.72e-2)" "unprognostic (2.66e-1)" "unprognostic (8.24e-2)" "validated prognostic favorable (1.54e-4)" "validated prognostic favorable (1.71e-5)" "unprognostic (1.09e-2)" "unprognostic (2.82e-1)" "unprognostic (1.49e-1)" "unprognostic (6.12e-2)" "unprognostic (2.17e-2)" "unprognostic (4.66e-2)" "unprognostic (3.89e-2)" "unprognostic (7.06e-2)" "unprognostic (1.83e-1)" "unprognostic (2.70e-2)" "unprognostic (8.89e-2)" "unprognostic (1.79e-1)" "unprognostic (6.58e-2)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "unprognostic (8.53e-2)" "unprognostic (8.46e-2)" "unprognostic (4.98e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-2)" "unprognostic (8.03e-2)" "unprognostic (9.40e-2)" "unprognostic (3.61e-3)" MRAS "M-RAs, R-RAS3, RRAS3" ENSG00000158186 "Muscle RAS oncogene homolog" O14807 3 138347648-138405534 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 111.6;heart muscle: 113.4" "Cell type enhanced" "Detected in many" "Adipocytes: 149.0;Adrenal cortex cells: 88.4;Astrocytes: 131.7;Bergmann glia: 86.9;Cardiomyocytes: 126.9;Gonadotrophs: 82.1;Late spermatids: 103.3" "Cell type enhanced" "Detected in many" "Adipocytes: 149.0;Glial cells: 131.7;Myocytes: 126.9" "Cell type enhanced" "Detected in all" "astrocyte: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "non-classical monocyte: 25.3" "Lineage enriched" "Detected in many" 9 "monocytes: 25.3" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 10768790.1;Microglia and Neuropil: 11195933.5;Neurons: 5177217.0" "Tissue enriched" "Detected in many" "cerebral cortex: 25992413.1" HPA042728 Approved Approved Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 7 Cytosol Vesicles "HPA042728: " "unprognostic (5.24e-3)" "unprognostic (7.18e-2)" "unprognostic (8.80e-2)" "unprognostic (3.13e-2)" "unprognostic (5.16e-3)" "unprognostic (8.41e-2)" "unprognostic (2.36e-1)" "unprognostic (2.68e-1)" "unprognostic (4.03e-1)" "unprognostic (3.94e-2)" "unprognostic (8.61e-3)" "unprognostic (1.94e-1)" "unprognostic (1.60e-2)" "unprognostic (2.23e-1)" "unprognostic (4.41e-3)" "unprognostic (2.15e-2)" "unprognostic (1.92e-1)" "unprognostic (9.26e-2)" "unprognostic (2.51e-2)" "unprognostic (1.56e-1)" "unprognostic (7.88e-3)" "unprognostic (2.35e-1)" "unprognostic (2.48e-1)" "unprognostic (9.43e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-2)" "unprognostic (1.24e-1)" "unprognostic (8.47e-3)" "unprognostic (7.38e-2)" "unprognostic (1.77e-1)" "unprognostic (8.30e-2)" MRFAP1 "PAM14, PGR1" ENSG00000179010 "Morf4 family associated protein 1" Q9Y605 4 6640091-6642729 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 657.3;Migrating cytotrophoblasts: 525.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Cell type enhanced" "Detected in many" "T-cells: 202645.0" "Tissue enhanced" "Detected in many" "intestine: 1447412.7" "CAB042447, HPA056367" Approved Supported Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 64 Nucleoplasm "CAB042447: , HPA056367: " "unprognostic (6.97e-3)" "unprognostic (9.76e-2)" "unprognostic (1.55e-1)" "unprognostic (1.84e-2)" "unprognostic (4.79e-2)" "unprognostic (1.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.36e-1)" "unprognostic (2.08e-1)" "unprognostic (2.65e-3)" "validated prognostic favorable (1.48e-6)" "validated prognostic favorable (1.78e-4)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (4.93e-3)" "validated prognostic unfavorable (1.52e-4)" "validated prognostic unfavorable (2.42e-4)" "unprognostic (5.07e-3)" "unprognostic (8.92e-2)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (4.12e-2)" "unprognostic (3.77e-1)" "unprognostic (1.32e-2)" "unprognostic (1.84e-1)" "unprognostic (1.28e-1)" "unprognostic (5.26e-2)" "unprognostic (6.05e-2)" "unprognostic (3.76e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (5.48e-4)" MRI1 "MGC3207, MRDI, mtnA, Ypr118w" ENSG00000037757 "Methylthioribose-1-phosphate isomerase 1" Q9BV20 19 13764522-13774282 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA042744, CAB045988" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No 13000 "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 23: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 8 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "CAB045988: , HPA042744: " "unprognostic (4.02e-2)" "unprognostic (2.42e-1)" "potential prognostic favorable (8.40e-4)" "unprognostic (1.56e-1)" "unprognostic (3.18e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-1)" "unprognostic (1.62e-1)" "unprognostic (1.44e-1)" "unprognostic (6.47e-2)" "unprognostic (1.35e-2)" "unprognostic (1.04e-1)" "unprognostic (3.68e-2)" "unprognostic (1.60e-1)" "unprognostic (1.97e-1)" "unprognostic (1.89e-2)" "unprognostic (6.27e-2)" "unprognostic (5.69e-2)" "unprognostic (7.70e-3)" "unprognostic (1.17e-1)" "unprognostic (5.55e-2)" "unprognostic (7.92e-2)" "unprognostic (6.93e-2)" "unprognostic (1.43e-3)" "potential prognostic favorable (8.29e-4)" "unprognostic (3.33e-3)" "potential prognostic unfavorable (9.41e-4)" "unprognostic (2.11e-2)" "unprognostic (1.72e-1)" "unprognostic (3.85e-1)" "unprognostic (8.42e-2)" MRM3 "FLJ10581, HC90, RMTL1, RNMTL1" ENSG00000171861 "Mitochondrial rRNA methyltransferase 3" Q9HC36 17 782353-792509 "Predicted intracellular proteins" "rRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 127.8;Late spermatids: 47.6" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 127.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 1156348.6" "Tissue enriched" "Detected in many" "heart muscle: 4881908.5" "HPA022534, HPA023031, HPA023292" Enhanced Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 46 Mitochondria "HPA022534: , HPA023031: , HPA023292: " "unprognostic (9.24e-2)" "unprognostic (1.14e-1)" "unprognostic (6.27e-2)" "unprognostic (3.64e-2)" "unprognostic (5.80e-2)" "unprognostic (1.44e-1)" "unprognostic (2.14e-2)" "unprognostic (1.47e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (5.68e-7)" "unprognostic (7.08e-3)" "unprognostic (3.77e-3)" "unprognostic (2.81e-1)" "unprognostic (2.35e-3)" "unprognostic (1.77e-1)" "unprognostic (1.88e-1)" "unprognostic (5.43e-2)" "unprognostic (7.65e-2)" "unprognostic (1.26e-1)" "unprognostic (3.36e-2)" "unprognostic (9.24e-2)" "unprognostic (9.30e-2)" "unprognostic (5.13e-2)" "unprognostic (3.82e-2)" "unprognostic (6.36e-2)" "unprognostic (2.23e-1)" "unprognostic (2.92e-1)" "unprognostic (9.93e-2)" "unprognostic (1.37e-2)" MROH2B "DKFZp781F0822, FLJ40243, HEATR7B2, SPIF" ENSG00000171495 "Maestro heat like repeat family member 2B" Q7Z745 5 40998017-41071342 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 193 "testis: 28.2" "Group enriched" "Detected in some" 5 "Adipocytes: 29.9;Early spermatids: 21.4;Late primary spermatocytes: 35.8;Late spermatids: 74.3" "Group enriched" "Detected in some" 7 "Adipocytes: 29.9;Spermatogenic cell types: 74.3" "Cell type enhanced" "Detected in single" "fibroblast: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 140 "lymphoid tissue: 13990.8" HPA059457 Enhanced Approved "Cytosol,Acrosome,Mid piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 72: Neuronal - Signal transduction" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Acrosome, Mid piece" Cytosol "HPA059457: " MROH8 "C20orf131, C20orf132, dJ621N11.3, dJ621N11.4" ENSG00000101353 "Maestro heat like repeat family member 8" 20 37101226-37179588 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 17.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 71.5;Myonuclei: 67.7;Retinal ganglion cells: 96.6" "Cell type enhanced" "Detected in many" "Neuronal cells: 96.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 2.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA058316, HPA060298" Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 55: Myocytes - Oxidative muscle function" Nucleoplasm "Vesicles, Cytosol" "HPA058316: , HPA060298: " "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (1.81e-2)" "unprognostic (1.43e-2)" "unprognostic (4.73e-2)" "unprognostic (2.49e-2)" "unprognostic (3.79e-1)" "unprognostic (1.64e-3)" "unprognostic (2.06e-1)" "unprognostic (1.03e-1)" "unprognostic (6.41e-3)" "unprognostic (2.41e-1)" MRPL23 "L23MRP, RPL23L" ENSG00000214026 "Mitochondrial ribosomal protein L23" Q16540 11 1947278-1984522 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 174.7;Epididymal efferent duct ciliated cells: 159.9;Extravillous trophoblasts: 170.6;Parietal cells: 224.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Large ducts: 20581295.0" "Tissue enhanced" "Detected in many" "blood vessel: 8071872.9" HPA050406 Approved Approved "Nucleoli fibrillar center,Mitochondria" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 93 "Nucleoli fibrillar center, Mitochondria" "HPA050406: " "unprognostic (2.60e-2)" "unprognostic (7.22e-2)" "unprognostic (1.26e-1)" "potential prognostic favorable (7.26e-5)" "unprognostic (1.09e-1)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (4.75e-4)" "unprognostic (3.84e-2)" "unprognostic (2.98e-1)" "unprognostic (1.47e-1)" "unprognostic (1.50e-2)" "unprognostic (2.68e-2)" "unprognostic (1.16e-1)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (3.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.10e-1)" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (3.17e-1)" "unprognostic (7.23e-2)" "unprognostic (1.45e-1)" "unprognostic (3.12e-1)" "unprognostic (6.45e-2)" "unprognostic (3.90e-2)" "unprognostic (3.75e-1)" "unprognostic (2.87e-1)" "unprognostic (2.05e-3)" "unprognostic (3.93e-2)" MRPL28 "MAAT1, p15" ENSG00000086504 "Mitochondrial ribosomal protein L28" Q13084 16 366969-371289 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 218.0;Late spermatids: 365.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 365.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 7141157.0;Large ducts: 7648814.9" "Group enriched" "Detected in many" "bone marrow: 960928.8;heart muscle: 3535990.6" "HPA030594, CAB033542, HPA055589" Supported Supported Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 118 Mitochondria "CAB033542: , HPA030594: , HPA055589: " "unprognostic (1.94e-1)" "unprognostic (7.80e-2)" "unprognostic (3.81e-1)" "unprognostic (3.48e-1)" "unprognostic (1.64e-1)" "unprognostic (2.77e-1)" "unprognostic (4.35e-2)" "unprognostic (1.99e-1)" "unprognostic (1.73e-2)" "unprognostic (1.86e-1)" "unprognostic (1.44e-2)" "unprognostic (1.71e-1)" "unprognostic (8.73e-2)" "unprognostic (1.07e-2)" "unprognostic (8.43e-3)" "unprognostic (2.84e-3)" "unprognostic (2.15e-2)" "unprognostic (2.83e-3)" "unprognostic (1.26e-1)" "unprognostic (2.63e-2)" "unprognostic (1.39e-1)" "unprognostic (1.95e-3)" "unprognostic (3.68e-3)" "unprognostic (2.82e-1)" "unprognostic (1.47e-1)" "unprognostic (1.87e-1)" "unprognostic (2.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.97e-1)" "unprognostic (2.64e-1)" "unprognostic (1.54e-1)" MRPL36 "L36mt, MRP-L36, PRPL36, RPMJ" ENSG00000171421 "Mitochondrial ribosomal protein L36" Q9P0J6 5 1798385-1801366 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 430.9;Esophageal basal cells: 220.8;Esophageal suprabasal cells: 202.6;Late primary spermatocytes: 498.7;Late spermatids: 598.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 598.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA047238 Approved Supported "Nuclear bodies,Mitochondria" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 29: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 1 Mitochondria "Nuclear bodies" "HPA047238: " "potential prognostic unfavorable (6.54e-5)" "potential prognostic unfavorable (9.99e-4)" "unprognostic (3.86e-2)" "unprognostic (1.28e-2)" "unprognostic (6.78e-2)" "unprognostic (1.45e-1)" "unprognostic (1.92e-3)" "unprognostic (1.26e-1)" "unprognostic (2.38e-2)" "unprognostic (8.11e-2)" "unprognostic (2.72e-3)" "unprognostic (1.11e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (2.78e-5)" "unprognostic (4.69e-3)" "unprognostic (5.47e-2)" "unprognostic (2.92e-3)" "unprognostic (1.28e-2)" "unprognostic (2.75e-1)" "unprognostic (1.61e-1)" "unprognostic (1.20e-1)" "unprognostic (9.19e-2)" "unprognostic (1.84e-1)" "unprognostic (4.68e-2)" "unprognostic (1.94e-1)" "unprognostic (3.68e-1)" "unprognostic (1.37e-2)" "unprognostic (2.50e-1)" "unprognostic (2.64e-1)" "unprognostic (3.64e-1)" "unprognostic (1.32e-2)" MRPL37 "MRP-L2, RPML2" ENSG00000116221 "Mitochondrial ribosomal protein L37" Q9BZE1 1 54184041-54225464 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 191.0;Esophageal suprabasal cells: 174.5;Extravillous trophoblasts: 167.4;Hepatocytes: 201.2;Migrating cytotrophoblasts: 173.5;Oocytes: 188.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Large ducts: 26964035.6" "Tissue enhanced" "Detected in many" "intestine: 5962069.5" "HPA025767, HPA025826, HPA025951" Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 105 Mitochondria "HPA025767: , HPA025826: , HPA025951: " "unprognostic (1.12e-1)" "unprognostic (1.32e-1)" "unprognostic (6.26e-2)" "unprognostic (3.45e-1)" "potential prognostic favorable (1.70e-4)" "unprognostic (5.16e-2)" "unprognostic (1.98e-1)" "unprognostic (4.00e-2)" "unprognostic (6.10e-2)" "unprognostic (5.66e-3)" "potential prognostic favorable (3.80e-4)" "unprognostic (1.07e-1)" "unprognostic (5.93e-2)" "validated prognostic unfavorable (1.20e-6)" "validated prognostic unfavorable (8.56e-4)" "unprognostic (5.56e-3)" "unprognostic (2.15e-3)" "unprognostic (9.24e-2)" "unprognostic (5.14e-1)" "unprognostic (2.31e-1)" "unprognostic (4.15e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (7.61e-2)" "unprognostic (1.16e-1)" "unprognostic (3.28e-3)" "unprognostic (2.59e-1)" "unprognostic (2.90e-1)" "unprognostic (5.40e-2)" "unprognostic (3.17e-1)" "unprognostic (1.14e-1)" "unprognostic (3.92e-1)" MRPL52 ENSG00000172590 "Mitochondrial ribosomal protein L52" Q86TS9 14 22829879-22835037 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 405.6;Gastric progenitor cells: 588.3" "Cell type enhanced" "Detected in all" "Proliferating cells: 588.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 612335.1;Large ducts: 1103265.2" "Tissue enriched" "Detected in many" "liver: 6808137.1" HPA012319 Approved Supported Nucleoplasm,Mitochondria Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 98 Mitochondria Nucleoplasm "HPA012319: " "unprognostic (1.00e-1)" "unprognostic (1.18e-1)" "unprognostic (2.16e-2)" "unprognostic (6.91e-2)" "unprognostic (4.14e-3)" "unprognostic (1.06e-2)" "unprognostic (2.29e-1)" "unprognostic (1.82e-3)" "unprognostic (2.17e-3)" "unprognostic (6.11e-3)" "unprognostic (3.47e-3)" "unprognostic (1.83e-3)" "unprognostic (5.24e-2)" "unprognostic (1.74e-3)" "unprognostic (2.11e-3)" "unprognostic (2.11e-3)" "unprognostic (5.04e-2)" "unprognostic (1.68e-1)" "unprognostic (6.27e-2)" "unprognostic (1.98e-1)" "unprognostic (5.02e-2)" "unprognostic (2.46e-2)" "unprognostic (8.34e-2)" "unprognostic (9.06e-2)" "unprognostic (1.68e-1)" "unprognostic (2.14e-1)" "unprognostic (2.43e-2)" "unprognostic (3.85e-1)" "unprognostic (2.78e-1)" "unprognostic (8.81e-2)" "unprognostic (5.67e-2)" MRPL54 ENSG00000183617 "Mitochondrial ribosomal protein L54" Q6P161 19 3762682-3768575 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 291.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA042117, HPA046767" Uncertain Approved Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 14 Mitochondria "HPA042117: , HPA046767: " "unprognostic (2.05e-1)" "unprognostic (3.98e-1)" "unprognostic (2.98e-1)" "unprognostic (1.10e-2)" "unprognostic (2.17e-1)" "unprognostic (8.08e-3)" "unprognostic (8.79e-2)" "unprognostic (2.03e-1)" "unprognostic (9.89e-2)" "unprognostic (4.50e-2)" "unprognostic (6.94e-3)" "unprognostic (7.69e-3)" "potential prognostic favorable (6.62e-7)" "unprognostic (9.36e-3)" "unprognostic (5.96e-2)" "unprognostic (8.56e-3)" "unprognostic (7.84e-2)" "unprognostic (7.18e-2)" "unprognostic (3.70e-1)" "unprognostic (1.16e-1)" "unprognostic (2.44e-1)" "unprognostic (4.01e-2)" "unprognostic (1.59e-1)" "unprognostic (2.48e-1)" "unprognostic (1.57e-2)" "unprognostic (2.75e-1)" "unprognostic (2.77e-1)" "unprognostic (3.39e-1)" "unprognostic (2.53e-1)" "unprognostic (7.88e-2)" "potential prognostic favorable (1.98e-4)" MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 92.8;Esophageal suprabasal cells: 97.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 18645444.3" "Tissue enhanced" "Detected in many" "fallopian tube: 6232813.2" "HPA003634, HPA076987" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 172 Mitochondria "Nucleoplasm, Plasma membrane" "HPA003634: , HPA076987: " "unprognostic (1.43e-1)" "unprognostic (8.51e-2)" "unprognostic (1.10e-1)" "potential prognostic favorable (1.47e-4)" "unprognostic (1.50e-1)" "unprognostic (1.40e-1)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (2.81e-3)" "unprognostic (6.67e-3)" "unprognostic (3.78e-1)" "unprognostic (4.60e-2)" "potential prognostic unfavorable (9.76e-4)" "unprognostic (2.48e-2)" "potential prognostic unfavorable (4.69e-4)" "unprognostic (1.11e-1)" "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (1.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.30e-1)" "unprognostic (1.03e-3)" "unprognostic (3.81e-3)" "unprognostic (2.73e-2)" "unprognostic (3.39e-1)" "unprognostic (6.68e-2)" "unprognostic (2.00e-1)" "unprognostic (1.33e-1)" "unprognostic (2.33e-1)" MRPS27 KIAA0264 ENSG00000113048 "Mitochondrial ribosomal protein S27" Q92552 5 72214953-72321717 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Translation regulation" "Ribonucleoprotein, Ribosomal protein, RNA-binding, rRNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "heart muscle: 12757119.6" HPA071751 Approved Supported Nucleoli,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 122 Mitochondria Nucleoli "HPA071751: " "unprognostic (6.02e-3)" "unprognostic (1.45e-1)" "unprognostic (7.58e-2)" "unprognostic (4.73e-2)" "unprognostic (4.70e-2)" "unprognostic (2.58e-2)" "unprognostic (2.88e-2)" "unprognostic (3.61e-1)" "unprognostic (1.16e-1)" "unprognostic (2.88e-3)" "potential prognostic favorable (1.71e-4)" "unprognostic (5.65e-3)" "unprognostic (1.74e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-2)" "unprognostic (1.31e-2)" "unprognostic (3.39e-2)" "unprognostic (4.04e-2)" "unprognostic (2.82e-1)" "unprognostic (8.04e-3)" "unprognostic (1.50e-3)" "unprognostic (6.49e-2)" "unprognostic (3.25e-1)" "unprognostic (3.14e-1)" "unprognostic (1.20e-2)" "unprognostic (3.48e-1)" "unprognostic (5.61e-2)" "unprognostic (6.44e-2)" "unprognostic (5.09e-2)" "unprognostic (1.96e-2)" "unprognostic (2.36e-2)" MRPS35 "MDS023, MRPS28" ENSG00000061794 "Mitochondrial ribosomal protein S35" P82673 12 27710822-27756295 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "blood vessel: 16540959.2" HPA038513 Supported Supported "Mitochondria,Cytosol,Connecting piece" No No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 97: Non-specific - Cellular respiration" 87 Mitochondria "Cytosol, Connecting piece" "HPA038513: " "unprognostic (1.30e-1)" "unprognostic (1.14e-3)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (8.11e-2)" "unprognostic (1.51e-1)" "unprognostic (3.89e-1)" "unprognostic (1.67e-2)" "unprognostic (3.38e-1)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (3.01e-4)" "potential prognostic favorable (7.24e-6)" "unprognostic (1.84e-1)" "unprognostic (1.14e-1)" "validated prognostic unfavorable (5.33e-5)" "validated prognostic unfavorable (5.82e-5)" "potential prognostic unfavorable (1.11e-4)" "unprognostic (3.45e-3)" "unprognostic (1.07e-2)" "unprognostic (2.24e-1)" "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (1.60e-2)" "unprognostic (3.04e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (9.43e-4)" "unprognostic (7.16e-2)" "unprognostic (3.61e-2)" "unprognostic (7.92e-2)" "unprognostic (1.44e-1)" "unprognostic (7.60e-2)" "unprognostic (9.86e-2)" MRPS5 "MRP-S5, S5mt" ENSG00000144029 "Mitochondrial ribosomal protein S5" P82675 2 95085369-95122006 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 71.6;Bergmann glia: 72.5;Brain excitatory neurons: 83.5;Brain inhibitory neurons: 73.0;Choroid plexus epithelial cells: 69.9;Distal convoluted tubule cells: 83.6;Oligodendrocyte progenitor cells: 69.7;Oligodendrocytes: 84.5;Other brain neurons: 74.9;Renal collecting duct intercalated cells: 107.9;Renal connecting tubule cells: 68.1" "Cell type enhanced" "Detected in many" "Ductal cells: 107.9;Glial cells: 84.5;Neuronal cells: 83.5;Renal nephron cells: 83.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22355265.5" HPA055765 Approved Supported "Midbody,Primary cilium,Mitochondria" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 102: Non-specific - Mixed function" 73 Mitochondria "Midbody, Primary cilium" "HPA055765: " "unprognostic (5.45e-3)" "unprognostic (4.52e-3)" "unprognostic (6.05e-3)" "unprognostic (1.64e-1)" "unprognostic (1.82e-1)" "unprognostic (2.01e-1)" "unprognostic (3.39e-2)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (5.49e-7)" "unprognostic (1.57e-2)" "potential prognostic favorable (9.41e-6)" "unprognostic (1.67e-2)" "unprognostic (2.90e-1)" "validated prognostic unfavorable (8.43e-5)" "validated prognostic unfavorable (1.10e-6)" "potential prognostic unfavorable (2.70e-4)" "unprognostic (7.85e-2)" "unprognostic (4.77e-3)" "unprognostic (1.65e-1)" "unprognostic (1.45e-2)" "unprognostic (1.44e-1)" "unprognostic (8.53e-2)" "unprognostic (4.74e-3)" "unprognostic (1.50e-2)" "unprognostic (1.66e-1)" "unprognostic (3.73e-1)" "unprognostic (2.68e-1)" "unprognostic (1.89e-1)" "unprognostic (5.30e-1)" "unprognostic (1.79e-2)" "unprognostic (1.16e-1)" MRPS7 "MRP-S, RP-S7, RPMS7" ENSG00000125445 "Mitochondrial ribosomal protein S7" Q9Y2R9 17 75261674-75266376 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 231.3;Esophageal suprabasal cells: 240.0;Late spermatids: 846.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 846.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "heart muscle: 9026250.9" "HPA022522, HPA023007" Supported Approved Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 94 Mitochondria "HPA022522: , HPA023007: " "unprognostic (1.28e-1)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (8.64e-2)" "potential prognostic favorable (4.62e-4)" "unprognostic (2.79e-1)" "unprognostic (4.23e-2)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (1.70e-4)" "unprognostic (5.77e-2)" "potential prognostic favorable (6.89e-4)" "unprognostic (8.23e-3)" "unprognostic (1.56e-2)" "validated prognostic unfavorable (7.79e-4)" "validated prognostic unfavorable (1.92e-5)" "unprognostic (9.65e-3)" "unprognostic (1.29e-1)" "unprognostic (9.03e-2)" "unprognostic (6.70e-3)" "unprognostic (2.80e-2)" "unprognostic (4.70e-2)" "unprognostic (4.51e-2)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (3.02e-2)" "unprognostic (2.01e-1)" "unprognostic (1.44e-1)" "unprognostic (2.00e-1)" "unprognostic (1.41e-1)" "unprognostic (4.47e-1)" "unprognostic (1.18e-1)" MRPS9 "MRP-S9, RPMS9, S9mt" ENSG00000135972 "Mitochondrial ribosomal protein S9" P82933 2 105038069-105099960 "Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 218.9" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 218.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "pancreas: 7001295.4;skeletal muscle: 7466142.9" "HPA043476, HPA048479" Supported Supported Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 111 Mitochondria "HPA043476: , HPA048479: " "unprognostic (5.49e-3)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (1.35e-1)" "unprognostic (8.78e-2)" "unprognostic (2.17e-1)" "unprognostic (4.31e-2)" "unprognostic (2.30e-1)" "unprognostic (1.46e-2)" "unprognostic (4.71e-3)" "unprognostic (1.06e-2)" "potential prognostic favorable (2.04e-5)" "unprognostic (1.36e-3)" "unprognostic (3.17e-1)" "validated prognostic unfavorable (1.91e-7)" "validated prognostic unfavorable (1.20e-4)" "unprognostic (6.14e-3)" "unprognostic (5.82e-2)" "unprognostic (1.53e-2)" "unprognostic (1.12e-2)" "unprognostic (1.98e-1)" "unprognostic (4.47e-2)" "unprognostic (3.92e-1)" "unprognostic (1.69e-1)" "unprognostic (1.38e-1)" "unprognostic (9.47e-2)" "unprognostic (1.60e-1)" "unprognostic (2.94e-1)" "unprognostic (3.14e-1)" "unprognostic (4.67e-1)" "unprognostic (8.10e-2)" "unprognostic (1.94e-1)" MRRF RRF ENSG00000148187 "Mitochondrial ribosome recycling factor" Q96E11 9 122264603-122331337 "Predicted intracellular proteins" "Protein biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 295.4;Late spermatids: 280.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 295.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA047177, HPA049987" Supported Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 20 "Microtubules, Cytokinetic bridge" "HPA047177: , HPA049987: " "unprognostic (2.78e-1)" "potential prognostic unfavorable (2.00e-4)" "unprognostic (3.73e-1)" "unprognostic (5.06e-2)" "unprognostic (2.64e-1)" "unprognostic (2.10e-2)" "unprognostic (8.11e-2)" "unprognostic (9.94e-3)" "unprognostic (1.55e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (7.47e-9)" "unprognostic (1.06e-2)" "unprognostic (1.08e-1)" "unprognostic (5.80e-2)" "unprognostic (8.77e-2)" "unprognostic (9.10e-3)" "unprognostic (4.27e-2)" "unprognostic (1.65e-1)" "unprognostic (2.89e-1)" "unprognostic (3.61e-2)" "unprognostic (3.11e-2)" "unprognostic (4.74e-3)" "unprognostic (2.72e-2)" "unprognostic (2.70e-1)" "unprognostic (1.91e-2)" "unprognostic (3.49e-2)" "unprognostic (8.46e-2)" "unprognostic (1.96e-1)" "unprognostic (1.58e-1)" "unprognostic (7.12e-2)" "unprognostic (1.71e-1)" MRTFA "BSAC, KIAA1438, MAL, MKL, MKL1, MRTF-A" ENSG00000196588 "Myocardin related transcription factor A" Q969V6 22 40410281-40636719 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Actin-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 694.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 189.9" "Group enriched" "Detected in all" 5 "dendritic cells: 93.0;granulocytes: 189.9;monocytes: 58.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA030782 Approved Supported "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 29: Non-specific - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 51: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 103: Non-specific - Basic cellular processes" 11 Nucleoplasm "Nuclear membrane, Cytosol" "HPA030782: " "unprognostic (1.23e-2)" "unprognostic (1.49e-2)" "unprognostic (1.37e-2)" "unprognostic (3.83e-1)" "unprognostic (3.05e-2)" "unprognostic (7.16e-2)" "unprognostic (5.46e-2)" "unprognostic (2.51e-1)" "unprognostic (9.92e-2)" "unprognostic (4.11e-3)" "unprognostic (1.18e-1)" "unprognostic (2.66e-1)" "unprognostic (5.83e-3)" "unprognostic (8.73e-3)" "unprognostic (7.99e-2)" "unprognostic (1.27e-1)" "unprognostic (2.69e-2)" "unprognostic (3.48e-3)" "unprognostic (1.43e-1)" "unprognostic (8.92e-2)" "unprognostic (3.34e-2)" "unprognostic (1.46e-1)" "unprognostic (8.17e-2)" "potential prognostic favorable (6.13e-4)" "unprognostic (3.47e-1)" "unprognostic (5.36e-2)" "unprognostic (2.16e-1)" "unprognostic (3.28e-3)" "unprognostic (1.13e-1)" MRTO4 "C1orf33, dJ657E11.4, MRT4" ENSG00000053372 "MRT4 homolog, ribosome maturation factor" Q9UKD2 1 19251805-19260128 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 127.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "bone marrow: 1372236.2;fallopian tube: 1835846.5;intestine: 3183306.1;lymphoid tissue: 4333934.1" HPA026446 Approved Approved "Nucleoplasm,Nuclear membrane,Nucleoli" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 19 "Nucleoplasm, Nuclear membrane" Nucleoli "HPA026446: " "unprognostic (7.59e-2)" "unprognostic (2.80e-1)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.95e-1)" "unprognostic (2.65e-1)" "unprognostic (3.78e-1)" "unprognostic (3.15e-2)" "unprognostic (2.46e-3)" "unprognostic (7.76e-3)" "unprognostic (6.65e-2)" "unprognostic (1.44e-1)" "unprognostic (1.01e-1)" "validated prognostic unfavorable (1.01e-11)" "validated prognostic unfavorable (7.74e-8)" "unprognostic (1.70e-3)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (9.25e-2)" "unprognostic (6.93e-2)" "unprognostic (2.64e-1)" "unprognostic (9.00e-2)" "unprognostic (4.15e-3)" "unprognostic (2.20e-1)" "unprognostic (2.11e-2)" "unprognostic (2.01e-1)" "unprognostic (1.99e-2)" "unprognostic (8.11e-2)" "unprognostic (2.69e-1)" "unprognostic (3.71e-2)" "unprognostic (1.18e-1)" "unprognostic (2.38e-2)" MS4A1 "B1, Bp35, CD20, FMC7" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 631.0" "Cell type enriched" "Detected in some" 52 "B-cells: 884.8" "Cell type enriched" "Detected in many" 52 "B-cells: 884.8" "Cell type enriched" "Detected in single" 99 "leukocyte: 50.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 627.9;naive B-cell: 630.0" "Lineage enriched" "Detected in many" 96 "B-cells: 630.0" "Cancer enriched" "Detected in some" 6 "lymphoma: 397.8" "Adrenal gland - T-cells, Lung - B-cells (Lung), Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "B-cells: 10017612.2;T-cells: 3121050.8" "Tissue enriched" "Detected in some" "lymphoid tissue: 30318168.9" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 34 "Plasma membrane" "CAB000015: , HPA014341: , HPA014391: " "unprognostic (1.71e-1)" "validated prognostic favorable (3.10e-4)" "validated prognostic favorable (2.75e-5)" "potential prognostic favorable (4.40e-5)" "unprognostic (1.25e-1)" "unprognostic (9.81e-2)" "potential prognostic favorable (9.96e-7)" "unprognostic (6.54e-3)" "unprognostic (9.61e-2)" "unprognostic (1.54e-2)" "potential prognostic favorable (1.29e-4)" "unprognostic (3.75e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (6.53e-2)" "unprognostic (8.62e-2)" "unprognostic (3.32e-1)" "unprognostic (3.46e-2)" "unprognostic (4.36e-2)" "unprognostic (3.36e-3)" "unprognostic (2.04e-1)" "unprognostic (1.93e-1)" "unprognostic (6.81e-2)" "unprognostic (6.82e-2)" MSGN1 pMesogenin1 ENSG00000151379 "Mesogenin 1" A6NI15 2 17816460-17817798 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 5 "choroid plexus: 1.1" "Cell type enhanced" "Detected in single" "Sertoli cells: 1.1" "Cell type enhanced" "Detected in single" "Reproductive supporting cells: 1.1" "Cell type enhanced" "Detected in single" "choroid plexus epithelial cell: 1.1" "Not detected" "Not detected" "Region enhanced" "Detected in single" "choroid plexus: 1.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA067516 Approved "Acrosome,Equatorial segment,Mid piece" NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 24 "Acrosome, Equatorial segment, Mid piece" "HPA067516: " MSH2 "COCA1, HNPCC, HNPCC1, MSH-2" ENSG00000095002 "MutS homolog 2" P43246 2 47403067-47663146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 294.0;Erythrocyte progenitors: 145.5;Rod photoreceptor cells: 158.9" "Cell type enhanced" "Detected in many" "Neuronal cells: 294.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 90.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 115443446.1" "Low tissue specificity" "Detected in many" "CAB009572, HPA066845, CAB070867, CAB080131" Supported Supported Nucleoplasm NA Yes 18000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 79: Photoreceptor cells - Phototransduction" 79 Nucleoplasm "CAB009572: , CAB070867: , CAB080131: , HPA066845: " "unprognostic (1.50e-1)" "unprognostic (3.35e-1)" "unprognostic (1.19e-1)" "unprognostic (2.42e-1)" "unprognostic (3.56e-2)" "unprognostic (2.54e-1)" "unprognostic (3.41e-1)" "unprognostic (3.90e-3)" "unprognostic (9.82e-2)" "potential prognostic unfavorable (4.89e-4)" "potential prognostic favorable (1.29e-4)" "unprognostic (1.38e-1)" "unprognostic (2.10e-2)" "validated prognostic unfavorable (2.60e-7)" "validated prognostic unfavorable (3.63e-5)" "unprognostic (1.73e-2)" "unprognostic (1.64e-2)" "potential prognostic favorable (1.22e-4)" "unprognostic (3.47e-2)" "unprognostic (3.37e-1)" "unprognostic (1.66e-1)" "unprognostic (3.51e-3)" "unprognostic (1.13e-3)" "unprognostic (5.04e-2)" "unprognostic (5.02e-3)" "unprognostic (1.20e-1)" "unprognostic (1.03e-2)" "unprognostic (8.53e-3)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (4.95e-2)" MSH4 ENSG00000057468 "MutS homolog 4" O15457 1 75796882-75913242 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Meiosis DNA-binding "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 1.7;testis: 4.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 23.7;Brain inhibitory neurons: 23.1;Early primary spermatocytes: 81.5;Late primary spermatocytes: 20.0;Myonuclei: 85.5;Papillary tip epithelial cells: 19.9;Retinal ganglion cells: 23.2;Retinal horizontal cells: 48.1" "Cell type enhanced" "Detected in many" "Myocytes: 85.5;Neuronal cells: 48.1;Spermatogenic cell types: 81.5" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA028117 Approved "Nucleoplasm,Equatorial segment,Flagellar centriole,Mid piece" NA NA "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 12 Nucleoplasm "Equatorial segment, Flagellar centriole, Mid piece" "HPA028117: " "unprognostic (4.88e-2)" MSMP "PC-3, PSMP" ENSG00000215183 "Microseminoprotein, prostate associated" Q1L6U9 9 35752990-35756613 "Predicted secreted proteins" "Chemotaxis, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.1;pituitary gland: 1.3;placenta: 1.1" "Group enriched" "Detected in some" 7 "Early spermatids: 123.6;Late spermatids: 326.4" "Cell type enriched" "Detected in many" 11 "Spermatogenic cell types: 326.4" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 61.7;Thyroid Carcinoma (TCGA): 34.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 13 "prostate cancer: 70.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055174 Uncertain Supported Vesicles,Cytosol "Secreted in other tissues" Cytokine No No 14000 "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Vesicles Cytosol "HPA055174: " "unprognostic (6.84e-2)" "unprognostic (4.28e-2)" "unprognostic (3.84e-1)" "unprognostic (1.37e-1)" "unprognostic (3.17e-1)" "unprognostic (3.13e-2)" "unprognostic (9.34e-2)" "unprognostic (4.73e-2)" "unprognostic (2.66e-1)" "unprognostic (2.41e-2)" "unprognostic (1.95e-1)" "unprognostic (4.36e-1)" "unprognostic (5.59e-2)" "unprognostic (4.75e-2)" MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 85.5;liver: 61.6" "Cell type enhanced" "Detected in many" "Astrocytes: 321.0;Bergmann glia: 499.2;Brain excitatory neurons: 929.3;Brain inhibitory neurons: 365.2;Choroid plexus epithelial cells: 316.1;Ependymal cells: 286.7;Late spermatids: 228.0;Oligodendrocyte progenitor cells: 371.9;Proximal tubule cells: 784.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 316.1;Glial cells: 499.2;Neuronal cells: 929.3;Renal nephron cells: 784.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 5.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 8201324.4;Proximal tubules: 18517381.8" "Tissue enriched" "Detected in all" "kidney: 171953571.7" "HPA023804, HPA053069, HPA075766" Approved Supported Nucleoplasm,Cytosol No No 40000 "Cluster 7: Non-specific - Innate immune response" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 7 "Nucleoplasm, Cytosol" "HPA023804: , HPA053069: , HPA075766: " "unprognostic (1.62e-2)" "unprognostic (4.79e-2)" "unprognostic (2.31e-2)" "unprognostic (2.67e-1)" "unprognostic (1.53e-1)" "unprognostic (9.63e-2)" "unprognostic (2.60e-2)" "unprognostic (1.78e-3)" "unprognostic (9.41e-2)" "unprognostic (4.23e-3)" "unprognostic (6.03e-3)" "potential prognostic favorable (5.73e-4)" "unprognostic (1.71e-1)" "unprognostic (8.14e-2)" "unprognostic (2.60e-1)" "unprognostic (4.43e-2)" "unprognostic (9.38e-2)" "unprognostic (1.68e-3)" "unprognostic (2.02e-1)" "unprognostic (8.87e-2)" "unprognostic (3.32e-2)" "unprognostic (4.65e-2)" "unprognostic (3.32e-2)" "unprognostic (1.11e-1)" "unprognostic (2.50e-2)" "unprognostic (1.88e-1)" "unprognostic (1.41e-1)" "unprognostic (3.39e-2)" "unprognostic (3.68e-1)" "unprognostic (1.02e-1)" MSS51 "FLJ39565, ZMYND17" ENSG00000166343 "MSS51 mitochondrial translational activator" Q4VC12 10 73423579-73433561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 244.5" "Cell type enriched" "Detected in many" 7 "Myonuclei: 120.8" "Cell type enriched" "Detected in many" 7 "Myocytes: 120.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Skeletal myocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA038564 Uncertain Vesicles,Cytosol NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 56: Non-specific - Sensory perception" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 19 Vesicles Cytosol "HPA038564: " "unprognostic (6.23e-2)" "potential prognostic favorable (2.59e-4)" "unprognostic (1.66e-1)" "unprognostic (1.12e-2)" "unprognostic (1.07e-2)" "unprognostic (2.89e-1)" "unprognostic (2.02e-1)" MT-CO1 "COI, COX1, MTCO1" ENSG00000198804 "Mitochondrially encoded cytochrome c oxidase I" P00395 MT 5904-7445 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Electron transport, Respiratory chain, Transport" Translocase "Deafness, Disease variant, Leber hereditary optic neuropathy, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265338.6;tongue: 172333.2" "Cell type enhanced" "Detected in many" "Colonocytes: 61581.5;Enterocytes: 89897.0;Hepatocytes: 54246.7" "Cell type enhanced" "Detected in many" "Enterocytes: 89897.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 6626033.7" "Tissue enhanced" "Detected in many" "skeletal muscle: 9111692.7" "CAB016241, HPA069328" Enhanced Supported "Mitochondria,End piece" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 1: Enterocytes - Absorption and Digestion" 12 Mitochondria "End piece" "CAB016241: , HPA069328: " "unprognostic (2.64e-1)" "unprognostic (6.46e-2)" "unprognostic (2.95e-2)" "unprognostic (5.03e-2)" "unprognostic (4.75e-3)" "unprognostic (2.29e-1)" "unprognostic (6.30e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (4.32e-5)" "unprognostic (3.13e-2)" "unprognostic (3.25e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (6.61e-5)" "unprognostic (8.70e-2)" "unprognostic (6.54e-2)" "unprognostic (4.12e-1)" "unprognostic (7.51e-3)" "unprognostic (1.18e-2)" "unprognostic (5.42e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-2)" "unprognostic (8.85e-2)" "unprognostic (4.35e-1)" "unprognostic (1.65e-1)" "unprognostic (3.15e-2)" "unprognostic (2.07e-2)" "unprognostic (2.55e-1)" "unprognostic (8.59e-3)" "unprognostic (1.86e-3)" MT-CYB "COB, CYTB, MTCYB, UQCR3" ENSG00000198727 "Mitochondrially encoded cytochrome b" P00156 MT 14747-15887 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Cataract, Deafness, Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 131222.4" "Cell type enhanced" "Detected in many" "Enterocytes: 23189.4;Pancreatic acinar cells: 24886.2;Retinal bipolar cells: 27394.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 81821039.3" "Tissue enhanced" "Detected in many" "heart muscle: 6047731.4" "CAB032215, HPA068400, HPA074796" Approved Supported Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Mitochondria "CAB032215: , HPA068400: , HPA074796: " "potential prognostic favorable (6.90e-4)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-2)" "unprognostic (1.18e-1)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" "unprognostic (1.19e-3)" "unprognostic (5.82e-3)" "unprognostic (5.50e-2)" "unprognostic (3.92e-3)" "potential prognostic favorable (6.45e-4)" "unprognostic (1.34e-1)" "unprognostic (5.48e-2)" "unprognostic (6.53e-2)" "unprognostic (9.93e-2)" "unprognostic (1.06e-2)" "unprognostic (8.29e-2)" "potential prognostic favorable (7.74e-4)" "unprognostic (8.06e-3)" "unprognostic (5.88e-2)" "unprognostic (1.00e-1)" "unprognostic (3.35e-2)" "unprognostic (1.88e-1)" "unprognostic (3.53e-3)" "unprognostic (2.92e-1)" "unprognostic (2.78e-2)" "unprognostic (7.09e-2)" MT-ND4L "MTND4L, NAD4L, ND4L" ENSG00000212907 "Mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4L" P03901 MT 10470-10766 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" Translocase "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 149995.1;tongue: 96029.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 3652.1;Urothelial cells: 1473.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 3652.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA075648 Approved Centrosome,Mitochondria,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 52: Non-specific - Cellular respiration" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" Mitochondria "Centrosome, Cytosol" "HPA075648: " "unprognostic (2.89e-2)" "unprognostic (9.45e-2)" "unprognostic (4.06e-2)" "unprognostic (2.34e-1)" "unprognostic (1.31e-1)" "unprognostic (2.85e-2)" "unprognostic (2.23e-1)" "unprognostic (1.32e-1)" "unprognostic (3.14e-3)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (1.09e-1)" "unprognostic (1.62e-1)" "unprognostic (6.71e-3)" "unprognostic (1.64e-1)" "unprognostic (7.57e-3)" "unprognostic (1.32e-2)" "unprognostic (2.26e-2)" "unprognostic (5.10e-3)" "unprognostic (1.89e-1)" "unprognostic (3.65e-2)" "unprognostic (1.41e-3)" "unprognostic (1.48e-2)" "unprognostic (2.60e-1)" "unprognostic (2.17e-1)" "unprognostic (5.55e-2)" "unprognostic (3.69e-2)" "unprognostic (3.79e-1)" "unprognostic (6.22e-3)" "unprognostic (2.39e-3)" MTAP "c86fus, MSAP" ENSG00000099810 "Methylthioadenosine phosphorylase" Q13126 9 21802636-21937651 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 12.6;Early spermatids: 19.1;Late primary spermatocytes: 29.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 29.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA046915, CAB080036, CAB080037" Approved Supported Nucleoplasm,Cytosol NA NA 1500000 "Cluster 30: Non-specific - DNA binding" "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 6 Cytosol Nucleoplasm "CAB080036: , CAB080037: , HPA046915: " "unprognostic (1.86e-2)" "unprognostic (6.71e-2)" "unprognostic (1.83e-1)" "unprognostic (4.40e-2)" "unprognostic (4.62e-3)" "potential prognostic unfavorable (4.20e-4)" "unprognostic (1.68e-1)" "potential prognostic favorable (3.93e-6)" "unprognostic (3.82e-2)" "unprognostic (2.51e-2)" "potential prognostic favorable (1.22e-5)" "unprognostic (5.29e-3)" "unprognostic (4.04e-2)" "unprognostic (1.01e-3)" "unprognostic (2.56e-3)" "unprognostic (4.55e-3)" "unprognostic (2.26e-3)" "unprognostic (1.83e-1)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (2.97e-2)" "unprognostic (2.53e-2)" "unprognostic (4.83e-2)" "unprognostic (4.14e-2)" "unprognostic (5.09e-3)" "unprognostic (4.12e-1)" "unprognostic (8.34e-2)" "unprognostic (2.36e-1)" "unprognostic (5.05e-2)" "unprognostic (2.37e-1)" MTBP ENSG00000172167 "MDM2 binding protein" Q96DY7 8 120445400-120542133 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Growth arrest, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 66.8;Early primary spermatocytes: 112.0;Erythrocyte progenitors: 57.0" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 112.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA025694, HPA050594" Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 40: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 13 Nucleoplasm "Nuclear bodies" "HPA025694: , HPA050594: " "unprognostic (1.01e-1)" "unprognostic (3.97e-2)" "unprognostic (4.96e-2)" "unprognostic (1.94e-1)" "unprognostic (1.94e-2)" "unprognostic (8.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.91e-2)" "unprognostic (1.29e-3)" "unprognostic (7.34e-2)" "unprognostic (2.93e-2)" "potential prognostic unfavorable (4.03e-5)" "unprognostic (1.24e-3)" "potential prognostic unfavorable (3.66e-5)" "unprognostic (1.07e-2)" "unprognostic (2.62e-2)" "unprognostic (9.17e-3)" "unprognostic (2.20e-2)" "unprognostic (1.66e-1)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (7.60e-5)" "unprognostic (8.19e-2)" "unprognostic (1.23e-2)" "unprognostic (6.29e-3)" "unprognostic (3.91e-2)" "unprognostic (1.16e-2)" "unprognostic (3.57e-1)" "unprognostic (6.08e-2)" MTERF4 "MGC61716, MTERFD2" ENSG00000122085 "Mitochondrial transcription termination factor 4" Q7Z6M4 2 241072169-241102332 "Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 296.1" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 296.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1413565.9;Large ducts: 929620.5" "Tissue enhanced" "Detected in some" "ovary: 55430625.5" HPA027097 Uncertain Supported Mitochondria,Cytosol Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 "Mitochondria, Cytosol" "HPA027097: " "unprognostic (9.18e-3)" "unprognostic (5.48e-2)" "unprognostic (9.37e-3)" "unprognostic (2.35e-2)" "unprognostic (1.57e-1)" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (4.08e-2)" "unprognostic (8.82e-2)" "validated prognostic favorable (8.61e-7)" "validated prognostic favorable (2.41e-4)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (5.98e-4)" "unprognostic (1.57e-1)" "unprognostic (3.69e-1)" "unprognostic (5.41e-2)" "unprognostic (5.68e-2)" "unprognostic (1.76e-3)" "unprognostic (1.75e-1)" "unprognostic (3.17e-2)" "unprognostic (4.15e-2)" "unprognostic (7.31e-2)" "unprognostic (8.65e-2)" "unprognostic (3.56e-1)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "unprognostic (1.73e-1)" MTHFR ENSG00000177000 "Methylenetetrahydrofolate reductase" P42898 1 11785723-11806455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 152.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 12639901.9" "Low tissue specificity" "Detected in many" "HPA063389, HPA076180, HPA077255" Enhanced Approved "Cell Junctions,Centrosome,Basal body" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 103: Non-specific - Basic cellular processes" 3 "Cell Junctions" "Centrosome, Basal body" "HPA063389: , HPA076180: , HPA077255: " "unprognostic (1.92e-3)" "unprognostic (1.78e-1)" "unprognostic (3.16e-2)" "unprognostic (6.24e-3)" "unprognostic (1.36e-2)" "unprognostic (9.52e-3)" "unprognostic (1.78e-1)" "unprognostic (1.41e-3)" "unprognostic (5.98e-3)" "unprognostic (3.58e-3)" "validated prognostic favorable (2.31e-6)" "validated prognostic favorable (7.09e-6)" "unprognostic (1.58e-3)" "unprognostic (1.43e-3)" "unprognostic (6.36e-2)" "unprognostic (2.15e-2)" "unprognostic (2.22e-2)" "unprognostic (1.93e-2)" "unprognostic (2.44e-2)" "unprognostic (1.55e-1)" "unprognostic (2.72e-1)" "unprognostic (2.25e-3)" "unprognostic (3.34e-2)" "unprognostic (3.80e-1)" "unprognostic (1.84e-1)" "unprognostic (1.66e-2)" "unprognostic (3.65e-1)" "unprognostic (4.11e-2)" "unprognostic (1.25e-2)" "unprognostic (2.76e-2)" "unprognostic (3.70e-2)" MTMR10 FLJ20313 ENSG00000166912 "Myotubularin related protein 10" Q9NXD2 15 30938941-30991628 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 77.6" "Cell type enhanced" "Detected in many" "Astrocytes: 107.9;Bergmann glia: 88.9;Choroid plexus epithelial cells: 80.6;Distal convoluted tubule cells: 142.9;Loop of henle epithelial cells: 130.7;Microglia: 115.6;Oligodendrocytes: 159.3;Papillary tip epithelial cells: 62.6;Podocytes: 95.5;Proximal tubule cells: 103.2;Renal collecting duct intercalated cells: 115.7;Renal collecting duct principal cells: 177.0;Renal connecting tubule cells: 223.6" "Group enriched" "Detected in many" 4 "Ciliated cells: 80.6;Ductal cells: 223.6;Glial cells: 159.3;Renal nephron cells: 142.9" "Cell type enhanced" "Detected in all" "oligodendrocyte: 242.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 13.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 6335644.9" "Tissue enriched" "Detected in many" "cerebral cortex: 4833207.7" HPA006081 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 "Nucleoplasm, Nuclear bodies" Cytosol "HPA006081: " "unprognostic (6.53e-2)" "unprognostic (1.14e-1)" "unprognostic (1.91e-3)" "unprognostic (6.37e-2)" "unprognostic (6.62e-2)" "unprognostic (2.10e-1)" "unprognostic (5.62e-2)" "unprognostic (2.62e-1)" "unprognostic (3.75e-2)" "unprognostic (1.34e-1)" "validated prognostic favorable (7.49e-8)" "validated prognostic favorable (2.66e-5)" "unprognostic (4.42e-3)" "unprognostic (1.60e-1)" "unprognostic (1.20e-1)" "unprognostic (4.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.64e-2)" "unprognostic (8.26e-2)" "unprognostic (2.54e-2)" "unprognostic (1.35e-1)" "unprognostic (6.73e-2)" "unprognostic (3.32e-1)" "unprognostic (2.23e-1)" "unprognostic (1.73e-2)" "unprognostic (3.99e-2)" "unprognostic (1.53e-1)" "unprognostic (1.37e-1)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (9.01e-4)" MTPAP "FLJ10486, PAPD1, SPAX4, TENT6" ENSG00000107951 "Mitochondrial poly(A) polymerase" Q9NVV4 10 30309801-30374448 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transcription" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.6" "Cell type enhanced" "Detected in many" "Early spermatids: 195.0;Late primary spermatocytes: 108.3" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 195.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "cerebral cortex: 173068.8;lymphoid tissue: 96513.4" "HPA038620, HPA058232" Approved Supported Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 52: Non-specific - Mitochondria" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 36 Mitochondria "Nucleoplasm, Vesicles" "HPA038620: , HPA058232: " "unprognostic (9.87e-2)" "unprognostic (5.23e-2)" "unprognostic (4.76e-2)" "unprognostic (8.54e-3)" "unprognostic (9.89e-2)" "unprognostic (2.02e-1)" "unprognostic (4.47e-3)" "potential prognostic favorable (2.79e-6)" "unprognostic (5.00e-2)" "unprognostic (5.63e-3)" "potential prognostic favorable (6.94e-4)" "unprognostic (4.71e-3)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (4.03e-2)" "unprognostic (4.48e-2)" "unprognostic (4.66e-2)" "unprognostic (1.81e-1)" "unprognostic (4.82e-3)" "unprognostic (1.81e-2)" "unprognostic (5.05e-1)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (2.07e-2)" "unprognostic (1.22e-2)" "unprognostic (2.68e-2)" "unprognostic (1.64e-1)" "unprognostic (4.10e-2)" "unprognostic (3.40e-2)" "unprognostic (3.38e-1)" "unprognostic (1.97e-3)" "unprognostic (9.69e-2)" MTR cblG ENSG00000116984 "5-methyltetrahydrofolate-homocysteine methyltransferase" Q99707 1 236795260-236921278 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Methionine biosynthesis" "Methyltransferase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 454.8;Renal collecting duct intercalated cells: 835.5;Renal collecting duct principal cells: 503.8;Renal connecting tubule cells: 486.5" "Cell type enhanced" "Detected in all" "Ductal cells: 835.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "heart muscle: 34379667.1;intestine: 14683924.3" HPA054915 Approved Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 72: Kidney - Transmembrane transport" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 13 "Microtubules, Primary cilium" "Cytokinetic bridge, Basal body, Cytosol" "HPA054915: " "unprognostic (2.30e-2)" "unprognostic (8.50e-2)" "unprognostic (2.63e-2)" "unprognostic (4.15e-2)" "unprognostic (2.54e-1)" "unprognostic (1.44e-2)" "unprognostic (1.73e-1)" "unprognostic (3.38e-1)" "unprognostic (1.41e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (7.87e-6)" "unprognostic (3.29e-2)" "unprognostic (8.02e-2)" "unprognostic (1.11e-1)" "unprognostic (9.75e-2)" "unprognostic (1.46e-1)" "unprognostic (1.67e-1)" "unprognostic (3.20e-1)" "unprognostic (9.10e-2)" "unprognostic (2.78e-2)" "unprognostic (5.82e-2)" "unprognostic (4.16e-2)" "unprognostic (3.54e-1)" "unprognostic (1.10e-1)" "unprognostic (3.90e-2)" "unprognostic (6.76e-2)" "unprognostic (1.33e-2)" "unprognostic (1.80e-3)" "unprognostic (4.82e-1)" "unprognostic (2.08e-3)" "unprognostic (8.46e-2)" MTRFR "C12orf65, COXPD7, FLJ38663, mtRF-R, SPG55" ENSG00000130921 "Mitochondrial translation release factor in rescue" Q9H3J6 12 123233385-123258079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" RNA-binding "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 55.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 140.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "heart muscle: 2120414.8" HPA057595 Approved Approved Nucleoplasm,Mitochondria,Cytosol No Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 80: Thymus - Adaptive immune response" "Cluster 9: Non-specific - Receptor signaling" "Cluster 38: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 4 "Nucleoplasm, Cytosol" Mitochondria "HPA057595: " "unprognostic (4.06e-2)" "unprognostic (6.07e-2)" "unprognostic (7.01e-2)" "unprognostic (3.59e-1)" "unprognostic (1.02e-1)" "unprognostic (1.74e-1)" "unprognostic (8.82e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (2.06e-1)" "unprognostic (6.43e-3)" "unprognostic (1.05e-2)" "unprognostic (9.24e-2)" "unprognostic (2.46e-1)" "validated prognostic unfavorable (4.05e-6)" "validated prognostic unfavorable (7.97e-4)" "unprognostic (1.35e-1)" "unprognostic (4.44e-2)" "unprognostic (4.56e-2)" "unprognostic (3.82e-2)" "unprognostic (5.17e-2)" "unprognostic (2.68e-1)" "unprognostic (4.04e-2)" "unprognostic (3.57e-3)" "potential prognostic unfavorable (3.35e-5)" "unprognostic (1.96e-1)" "unprognostic (5.26e-2)" "unprognostic (9.75e-2)" "unprognostic (1.84e-1)" "unprognostic (3.12e-2)" "unprognostic (2.03e-2)" "unprognostic (1.14e-1)" MTUS1 "ATBP, ATIP1, ATIP3, DKFZp586D1519, FLJ14295, ICIS, KIAA1288, MP44, MTSG1" ENSG00000129422 "Microtubule associated scaffold protein 1" Q9ULD2 8 17643795-17801094 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 717.5;Endometrial glandular cells: 743.8;Endometrial luminal cells: 815.3" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 889.0;oligodendrocyte: 679.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.4" "Lineage enriched" "Detected in single" 19 "T-cells: 1.8" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 7066175.9" "Group enriched" "Detected in some" "heart muscle: 694800.9;liver: 664688.8;lymphoid tissue: 283309.9" "HPA067903, HPA069795" Enhanced Nucleoli,Microtubules No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 11: White matter - Signal transduction" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 5 "Nucleoli, Microtubules" "HPA067903: , HPA069795: " "potential prognostic favorable (3.83e-4)" "unprognostic (2.53e-1)" "unprognostic (1.16e-3)" "unprognostic (1.26e-1)" "potential prognostic favorable (1.49e-4)" "unprognostic (6.01e-2)" "unprognostic (2.27e-1)" "unprognostic (6.71e-2)" "unprognostic (3.68e-3)" "potential prognostic unfavorable (4.89e-4)" "validated prognostic favorable (2.23e-5)" "validated prognostic favorable (5.05e-4)" "unprognostic (1.97e-3)" "unprognostic (2.58e-1)" "unprognostic (1.41e-1)" "unprognostic (7.28e-3)" "unprognostic (8.21e-2)" "unprognostic (8.75e-3)" "unprognostic (3.99e-1)" "unprognostic (4.37e-2)" "unprognostic (3.22e-2)" "unprognostic (4.32e-2)" "unprognostic (1.69e-1)" "unprognostic (2.88e-1)" "unprognostic (3.33e-2)" "unprognostic (5.72e-3)" "unprognostic (4.41e-1)" "unprognostic (5.01e-2)" "unprognostic (2.49e-1)" "unprognostic (3.51e-3)" "unprognostic (4.27e-1)" MTUS2 "CAZIP, ICIS, KIAA0774, TIP150" ENSG00000132938 "Microtubule associated scaffold protein 2" Q5JR59 13 28820339-29505947 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 12.9;heart muscle: 47.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 481.8;Brain inhibitory neurons: 560.7;Cardiomyocytes: 1357.5;Choroid plexus epithelial cells: 599.1;Gonadotrophs: 582.1;Lactotrophs: 830.5;Other brain neurons: 367.8;Pituitary stem cells: 317.6;Retinal amacrine cells: 530.1;Retinal bipolar cells: 911.1;Retinal ganglion cells: 529.2;Salivary ionocytes: 524.4;Somatotrophs: 594.3;Thyrotrophs: 597.8;Undifferentiated spermatogonia: 298.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 599.1;Ionocytes: 524.4;Myocytes: 1357.5;Neuronal cells: 911.1;Pituitary endocrine cells: 830.5" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 1736.6" "Cancer enhanced" "Detected in some" "Bladder Urothelial Carcinoma (TCGA): 2.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.5" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Capillaries: 12853618.0;Cardiomyocytes: 8600664.9" "Tissue enriched" "Detected in some" "heart muscle: 43019485.5" "HPA031473, HPA031474, HPA031475" Enhanced Supported "Microtubules,Cytokinetic bridge" Yes NA "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 139 "Microtubules, Cytokinetic bridge" "HPA031473: , HPA031474: , HPA031475: " "unprognostic (8.82e-2)" "unprognostic (1.20e-1)" "unprognostic (2.30e-3)" "unprognostic (1.12e-1)" "unprognostic (2.85e-3)" MUC5B "MG1, MUC5" ENSG00000117983 "Mucin 5B, oligomeric mucus/gel-forming" Q9HC84 11 1223066-1262172 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "salivary gland: 2643.1" "Group enriched" "Detected in some" 4 "Conjunctival goblet cells: 784.5;Endometrial secretory cells: 1975.7;Submucosal glandular cells: 1170.9" "Group enriched" "Detected in many" 5 "Glandular cells: 1170.9;Goblet cells: 784.5;Secretory cells: 1975.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 218.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 23.1" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skin - Eccrine sweat gland cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Large ducts: 6112231.1" "Tissue enriched" "Detected in all" "salivary gland: 1198316946.5" "HPA008246, CAB009396" Enhanced Supported Vesicles "Secreted in other tissues" "No annotated function" NA NA 5300000 "Cluster 82: Salivary gland - Secretion" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 5 Vesicles "CAB009396: , HPA008246: " "unprognostic (2.48e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (8.93e-4)" "unprognostic (2.03e-1)" "unprognostic (1.94e-3)" "unprognostic (1.42e-2)" "unprognostic (8.36e-2)" "unprognostic (1.56e-1)" "unprognostic (1.67e-1)" "unprognostic (4.08e-3)" "unprognostic (5.64e-2)" "unprognostic (3.18e-1)" "unprognostic (9.38e-2)" "unprognostic (1.32e-1)" "unprognostic (4.47e-2)" "unprognostic (4.84e-2)" "unprognostic (1.66e-1)" "unprognostic (3.32e-1)" "unprognostic (4.33e-3)" "unprognostic (2.44e-1)" "unprognostic (1.79e-2)" MVB12B "C9orf28, FAM125B, FLJ00001" ENSG00000196814 "Multivesicular body subunit 12B" Q9H7P6 9 126326829-126507041 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 110.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 437.9;Ependymal cells: 226.1;Microglia: 261.9;Oligodendrocytes: 603.4;Renal collecting duct intercalated cells: 265.4" "Cell type enhanced" "Detected in all" "Ciliated cells: 437.9;Glial cells: 603.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 976.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Oocytes: 935717.9;Skeletal myofibers: 3186345.6" "Tissue enriched" "Detected in many" "liver: 10278124.9" HPA043683 Supported "Vesicles,Primary cilium,Primary cilium tip,Primary cilium transition zone" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 80: Oligodendrocytes - Myelination" 6 Vesicles "Primary cilium, Primary cilium tip, Primary cilium transition zone" "HPA043683: " "unprognostic (1.71e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (1.82e-1)" "unprognostic (2.26e-3)" "unprognostic (8.07e-2)" "unprognostic (3.99e-3)" "unprognostic (1.57e-1)" "unprognostic (3.77e-1)" "unprognostic (2.11e-3)" "unprognostic (7.49e-2)" "unprognostic (1.21e-1)" "unprognostic (1.68e-2)" "unprognostic (1.02e-3)" "unprognostic (2.53e-1)" "unprognostic (8.18e-2)" "potential prognostic favorable (4.80e-4)" "unprognostic (5.26e-2)" "unprognostic (4.36e-1)" "unprognostic (1.14e-3)" "unprognostic (7.46e-3)" "unprognostic (1.96e-1)" "unprognostic (1.04e-2)" "unprognostic (1.60e-3)" "unprognostic (1.07e-1)" "unprognostic (6.85e-2)" "unprognostic (1.45e-1)" "unprognostic (2.55e-1)" "unprognostic (1.68e-1)" MX1 "IFI-78K, lncMX1-215, MxA" ENSG00000157601 "MX dynamin like GTPase 1" P20591 21 41420020-41470071 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 119.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 132.5;pDCs: 137.6" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 174.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 32871000.2;Macrophages: 70094328.6;T-cells: 33025169.5" "Tissue enriched" "Detected in many" "lymphoid tissue: 59373464.5" "HPA030917, HPA030918, HPA049724" Approved Approved Supported "Nuclear membrane,Cytosol" No NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 18 "Nuclear membrane, Cytosol" "HPA030917: , HPA030918: , HPA049724: " "unprognostic (3.23e-1)" "unprognostic (1.66e-1)" "unprognostic (2.00e-1)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (4.88e-2)" "unprognostic (2.57e-1)" "unprognostic (4.33e-2)" "unprognostic (7.64e-2)" "unprognostic (1.09e-1)" "unprognostic (4.54e-3)" "unprognostic (4.83e-2)" "unprognostic (1.47e-2)" "unprognostic (3.57e-2)" "unprognostic (2.68e-2)" "unprognostic (2.90e-2)" "unprognostic (1.12e-2)" "unprognostic (5.11e-2)" "unprognostic (2.60e-1)" "unprognostic (4.49e-1)" "unprognostic (1.80e-2)" "unprognostic (4.50e-3)" "unprognostic (3.30e-2)" "unprognostic (3.94e-1)" "unprognostic (2.77e-1)" "unprognostic (4.81e-3)" "unprognostic (2.63e-1)" "unprognostic (8.69e-2)" "unprognostic (1.80e-1)" "unprognostic (3.39e-1)" "unprognostic (5.48e-2)" MXI1 "bHLHc11, MAD2, MXD2, MXI" ENSG00000119950 "MAX interactor 1, dimerization protein" P50539 10 110207605-110287365 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocytes: 303.8;Esophageal apical cells: 317.3;Melanocytes: 341.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035319, HPA035320, HPA056762" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Cytosol" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 73: Brain - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 Nucleoplasm "Nucleoli, Nucleoli rim, Cytosol" "HPA035319: , HPA035320: , HPA056762: " "unprognostic (4.98e-1)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (2.64e-1)" "unprognostic (5.18e-2)" "unprognostic (7.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.38e-1)" "unprognostic (1.58e-2)" "unprognostic (2.77e-2)" "unprognostic (9.84e-3)" "potential prognostic favorable (2.69e-7)" "unprognostic (1.82e-2)" "unprognostic (6.77e-2)" "unprognostic (2.80e-2)" "unprognostic (4.49e-2)" "unprognostic (3.79e-1)" "unprognostic (4.55e-3)" "unprognostic (1.65e-1)" "unprognostic (4.25e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (5.50e-3)" "unprognostic (7.63e-2)" "unprognostic (8.61e-3)" "unprognostic (7.33e-3)" "unprognostic (2.47e-1)" "unprognostic (3.22e-1)" "unprognostic (1.49e-1)" "unprognostic (5.32e-2)" "unprognostic (4.22e-1)" "unprognostic (1.04e-1)" MYB c-myb ENSG00000118513 "MYB proto-oncogene, transcription factor" P10242 6 135181308-135219173 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 33.1;breast: 18.9;intestine: 24.9;lymphoid tissue: 61.5" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 107.8;Enteric stem cells: 83.8;Erythrocyte progenitors: 174.9;Fallopian tube ciliated cells: 79.1;Hematopoietic stem cells: 280.5;Mast cells: 70.4;Megakaryocyte progenitors: 102.3;Megakaryocyte-Erythroid progenitors: 314.5;Monocyte progenitors: 100.0;Neutrophil progenitors: 215.4;Respiratory ciliated cells: 124.6;Respiratory deuterosomal cells: 157.6;Thymocytes: 90.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 157.6;Erythrocytes: 174.9;Megakaryocytes: 314.5;Neutrophils: 215.4;Stem cells: 280.5" "Group enriched" "Detected in many" 7 "ependymal cell: 54.4;LAMP5-LHX6 and Chandelier: 49.1;medium spiny neuron: 30.6" "Group enriched" "Detected in many" 4 "Breast Invasive Carcinoma (TCGA): 37.9;Colon Adenocarcinoma (TCGA): 32.5;Rectum Adenocarcinoma (TCGA): 35.7;Stomach Adenocarcinoma (TCGA): 13.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "basophil: 4.5;eosinophil: 5.3;plasmacytoid DC: 1.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.5;granulocytes: 5.3" "Cancer enhanced" "Detected in many" "Leukemia: 175.7;lymphoma: 55.4" "Adipose subcutaneous - Mast cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Stomach - Mitotic cells (Stomach), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "CAB017704, HPA071605" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 26 Nucleoplasm Cytosol "CAB017704: , HPA071605: " "unprognostic (2.06e-1)" "unprognostic (5.37e-1)" "unprognostic (5.41e-2)" "unprognostic (6.34e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-3)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (1.80e-1)" "unprognostic (2.00e-3)" "unprognostic (9.39e-2)" "unprognostic (3.30e-2)" "unprognostic (1.99e-1)" "unprognostic (4.65e-2)" "unprognostic (7.13e-2)" "unprognostic (9.47e-2)" "unprognostic (1.19e-3)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" "unprognostic (6.15e-3)" "unprognostic (6.13e-2)" "unprognostic (1.77e-1)" MYBBP1A "FLJ37886, P160, PAP2, Pol5" ENSG00000132382 "MYB binding protein 1a" Q9BQG0 17 4538897-4555386 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Ribosome biogenesis, Transcription, Transcription regulation" "Activator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 59225370.2" "Low tissue specificity" "Detected in many" HPA005466 Supported Supported Nucleoli,Vesicles No No 49000 "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 84 Nucleoli Vesicles "HPA005466: " "unprognostic (5.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (1.46e-4)" "unprognostic (3.88e-1)" "unprognostic (4.59e-2)" "unprognostic (1.06e-1)" "unprognostic (9.71e-3)" "unprognostic (2.28e-1)" "unprognostic (6.08e-2)" "unprognostic (8.19e-2)" "unprognostic (3.02e-1)" "unprognostic (3.51e-1)" "unprognostic (6.01e-2)" "unprognostic (1.52e-2)" "unprognostic (3.38e-2)" "unprognostic (1.87e-2)" "unprognostic (6.37e-2)" "unprognostic (1.03e-1)" "unprognostic (9.03e-3)" "unprognostic (1.07e-2)" "unprognostic (1.05e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (8.17e-2)" "unprognostic (3.29e-2)" "unprognostic (1.75e-2)" "unprognostic (6.28e-2)" "unprognostic (2.62e-1)" "unprognostic (8.87e-3)" "unprognostic (1.50e-2)" MYBL2 "B-MYB, BMYB" ENSG00000101057 "MYB proto-oncogene like 2" P10244 20 43667019-43716495 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 86.6;lymphoid tissue: 51.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 54.5;Erythrocyte progenitors: 172.2;Extravillous trophoblasts: 38.4;Megakaryocyte progenitors: 62.3;Migrating cytotrophoblasts: 37.1;Monocyte progenitors: 65.8;Neutrophil progenitors: 44.9;pDCs: 123.2;Plasma cells: 117.9" "Cell type enhanced" "Detected in many" "dendritic cells: 123.2;Erythrocytes: 172.2;Plasma cells: 117.9" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 478.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 91.7" "Lineage enriched" "Detected in many" 34 "dendritic cells: 91.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 295953.5" "Not detected" "Not detected" "CAB017114, HPA030530, HPA055416" Uncertain Supported Nucleoplasm,Cytosol Yes Yes "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 62: Non-specific - Plasma proteins" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 35 Nucleoplasm Cytosol "CAB017114: , HPA030530: , HPA055416: " "unprognostic (1.53e-1)" "unprognostic (1.73e-2)" "unprognostic (1.35e-1)" "unprognostic (7.28e-2)" "unprognostic (1.76e-1)" "unprognostic (3.24e-2)" "unprognostic (1.70e-1)" "unprognostic (8.10e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (3.85e-6)" "validated prognostic unfavorable (2.06e-9)" "validated prognostic unfavorable (2.73e-6)" "potential prognostic unfavorable (9.83e-9)" "validated prognostic unfavorable (3.54e-9)" "validated prognostic unfavorable (9.59e-9)" "validated prognostic unfavorable (1.64e-5)" "validated prognostic unfavorable (7.37e-4)" "unprognostic (8.91e-2)" "unprognostic (7.00e-2)" "unprognostic (2.26e-1)" "unprognostic (1.07e-1)" "unprognostic (1.65e-3)" "unprognostic (5.02e-3)" "unprognostic (1.66e-2)" "unprognostic (1.08e-1)" "unprognostic (4.45e-2)" "unprognostic (7.46e-3)" "unprognostic (9.33e-2)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" "unprognostic (1.31e-1)" MYCBP AMY-1 ENSG00000214114 "MYC binding protein" Q99417 1 38862493-38873368 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 51.4;Endometrial ciliated cells: 24.7;Fallopian tube ciliated cells: 32.4;Late primary spermatocytes: 17.2;Megakaryocytes: 24.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 32.4;Megakaryocytes: 24.7;Spermatogenic cell types: 51.4" "Cell type enhanced" "Detected in many" "ependymal cell: 11.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 47344021.3" "Tissue enhanced" "Detected in all" "bone marrow: 133642877.5" "HPA041188, HPA078331" Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 30 Nucleoplasm Mitochondria "HPA041188: , HPA078331: " "unprognostic (9.87e-2)" "unprognostic (3.79e-2)" "unprognostic (1.25e-1)" "unprognostic (2.41e-2)" "potential prognostic favorable (2.51e-4)" "unprognostic (1.25e-2)" "unprognostic (9.23e-2)" "unprognostic (1.65e-1)" "unprognostic (1.69e-2)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (5.16e-2)" "unprognostic (3.21e-2)" "unprognostic (3.13e-1)" "potential prognostic unfavorable (1.73e-5)" "unprognostic (1.75e-3)" "unprognostic (3.90e-1)" "unprognostic (9.60e-2)" "unprognostic (3.49e-1)" "unprognostic (8.02e-2)" "unprognostic (1.35e-1)" "unprognostic (1.53e-2)" "unprognostic (3.12e-3)" "unprognostic (1.91e-1)" "unprognostic (4.81e-3)" "unprognostic (3.29e-2)" "unprognostic (8.79e-2)" "unprognostic (3.32e-2)" "unprognostic (2.59e-2)" "unprognostic (3.64e-1)" "unprognostic (1.36e-1)" "unprognostic (4.58e-1)" MYCL "bHLHe38, LMYC, MYCL1" ENSG00000116990 "MYCL proto-oncogene, bHLH transcription factor" P12524 1 39895426-39902256 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 63.9;skin 1: 37.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 43.5;Esophageal suprabasal cells: 30.6;Hepatocytes: 31.2;pDCs: 28.1;Prostatic hillock cells: 40.7;Respiratory deuterosomal cells: 79.8;Respiratory secretory cells: 26.1;Retinal pigment epithelial cells: 25.6;Urothelial cells: 85.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 85.7;Ciliated cells: 79.8" "Group enriched" "Detected in some" 4 "central nervous system macrophage: 3.7;committed oligodendrocyte precursor: 11.6" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 63.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 17.3;intermediate monocyte: 8.2;myeloid DC: 18.7;plasmacytoid DC: 22.8" "Group enriched" "Detected in many" 72 "dendritic cells: 22.8;monocytes: 17.3" "Cancer enhanced" "Detected in many" "lung cancer: 54.1;Myeloma: 31.7" "Breast - Breast glandular cells, Liver - Hepatocytes, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA063132, HPA074515" Enhanced "Nucleoplasm,Mitotic chromosome" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 69: Urothelial cells - Basic cellular functions" 4 Nucleoplasm "Mitotic chromosome" "HPA063132: , HPA074515: " "unprognostic (1.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.38e-1)" "unprognostic (8.05e-2)" "unprognostic (1.51e-1)" "unprognostic (2.12e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (7.28e-3)" "unprognostic (3.12e-1)" "unprognostic (4.92e-3)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (1.74e-2)" "unprognostic (6.04e-3)" "unprognostic (5.31e-2)" "unprognostic (3.17e-2)" "unprognostic (6.11e-2)" "unprognostic (5.24e-2)" "unprognostic (1.16e-2)" "unprognostic (3.66e-2)" "unprognostic (4.83e-2)" "unprognostic (2.01e-1)" "unprognostic (2.14e-2)" "unprognostic (6.57e-3)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (7.16e-2)" "unprognostic (1.33e-2)" "unprognostic (2.67e-1)" MYH10 NMMHCB ENSG00000133026 "Myosin heavy chain 10" P35580 17 8474207-8631376 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Host cell receptor for virus entry, Motor protein, Myosin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "blood vessel: 253.8" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 378.9;Epicardial cells: 723.2;Hepatic stellate cells: 387.3;Mesothelial cells: 335.7;Thyrotrophs: 352.9" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 723.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Skeletal muscle - Fibroblasts, Testis - Spermatogonia, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Smooth muscle cells: 11132704374.3" "Tissue enriched" "Detected in all" "blood vessel: 2510281799.4" "CAB017180, HPA047541, HPA057198" Enhanced Uncertain "Actin filaments,Mitochondria,Cytosol" NA NA 41000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 46 "Actin filaments" "Mitochondria, Cytosol" "CAB017180: , HPA047541: , HPA057198: " "unprognostic (3.73e-1)" "unprognostic (2.03e-1)" "potential prognostic favorable (5.26e-4)" "unprognostic (8.12e-3)" "unprognostic (9.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.24e-1)" "potential prognostic favorable (1.72e-4)" "unprognostic (2.29e-2)" "unprognostic (7.80e-3)" "potential prognostic favorable (6.28e-6)" "unprognostic (2.17e-3)" "unprognostic (1.82e-1)" "unprognostic (2.56e-1)" "unprognostic (1.08e-1)" "unprognostic (4.62e-2)" "unprognostic (2.86e-1)" "unprognostic (4.74e-2)" "unprognostic (2.97e-1)" "unprognostic (1.04e-1)" "unprognostic (7.44e-3)" "potential prognostic favorable (3.40e-4)" "unprognostic (3.24e-1)" "unprognostic (6.15e-2)" "unprognostic (9.55e-2)" "unprognostic (1.67e-1)" "unprognostic (3.18e-2)" "unprognostic (7.81e-3)" "unprognostic (2.60e-1)" "unprognostic (7.52e-2)" "unprognostic (8.71e-2)" MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36388010 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Host cell receptor for virus entry, Motor protein, Myosin, Receptor" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 530.2" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 1041.5;Neutrophils: 1873.8;Pancreatic acinar cells: 1111.2;Platelets: 1643.8" "Cell type enhanced" "Detected in all" "Neutrophils: 1873.8;Platelets: 1643.8" "Cell type enhanced" "Detected in all" "endothelial cell: 385.5;leukocyte: 332.7;vascular associated smooth muscle cell: 382.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 4717902556.8" "Low tissue specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 630000000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 156 "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: , HPA001644: , HPA064783: " "unprognostic (3.63e-2)" "unprognostic (3.27e-1)" "unprognostic (3.22e-1)" "unprognostic (1.26e-3)" "unprognostic (6.75e-2)" "unprognostic (3.86e-1)" "unprognostic (4.15e-1)" "unprognostic (1.70e-2)" "unprognostic (2.75e-3)" "unprognostic (5.55e-2)" "potential prognostic favorable (7.09e-5)" "unprognostic (1.48e-3)" "unprognostic (1.71e-1)" "unprognostic (5.07e-2)" "unprognostic (1.71e-1)" "unprognostic (6.74e-2)" "potential prognostic unfavorable (2.17e-5)" "unprognostic (4.63e-1)" "unprognostic (3.22e-1)" "unprognostic (4.29e-2)" "unprognostic (1.15e-1)" "unprognostic (3.49e-2)" "unprognostic (8.07e-2)" "unprognostic (2.36e-1)" "unprognostic (2.28e-2)" "unprognostic (8.78e-3)" "unprognostic (4.05e-1)" "unprognostic (2.77e-1)" "unprognostic (1.28e-1)" "unprognostic (1.22e-2)" "unprognostic (2.97e-1)" MYMX MINION ENSG00000262179 "Myomixer, myoblast fusion factor" A0A1B0GTQ4 6 44216926-44218234 "Disease related genes, Predicted intracellular proteins" Myogenesis "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Group enriched" "Detected in some" 4 "adipose tissue: 7.1;blood vessel: 1.9;breast: 6.7;pancreas: 5.2;stomach 1: 2.2" "Cell type enhanced" "Detected in some" "Conjunctival goblet cells: 1.9;Extravillous trophoblasts: 2.3;Gastric chief cells: 3.3;Kupffer cells: 4.1;Parietal cells: 5.3;pDCs: 10.9;Peritubular myoid cells: 1.8;Respiratory ionocytes: 5.1;Salivary basal cells: 1.4;Salivary duct cells: 2.3" "Cell type enhanced" "Detected in some" "dendritic cells: 10.9;Gastric glandular cells: 5.3;Ionocytes: 5.1;Mononuclear phagocytes: 4.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 3.4;Testicular Germ Cell Tumor (TCGA): 4.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 107 "plasmacytoid DC: 10.6" "Lineage enriched" "Detected in single" 107 "dendritic cells: 10.6" "Cancer enhanced" "Detected in some" "Rhabdoid: 5.8;Sarcoma: 14.5" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA051451 Supported Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 70: Non-specific - Protein processing" "Cluster 24: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" Vesicles "Mitochondria, Cytosol" "HPA051451: " "unprognostic (6.27e-2)" "unprognostic (1.65e-1)" MYO15B MYO15BP ENSG00000266714 "Myosin XVB" 17 75587800-75626849 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "intestine: 201.7" "Cell type enhanced" "Detected in many" "Colonocytes: 295.8;Enterocytes: 426.9;Tuft cells: 368.9" "Cell type enhanced" "Detected in many" "Enterocytes: 426.9;Secretory gland support: 368.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 113.2;ependymal cell: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.4;Gastric cancer: 16.9" "Skin - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA022857, HPA023105" Approved Cytosol No No "Cluster 77: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Cytosol "HPA022857: , HPA023105: " "unprognostic (3.26e-3)" "unprognostic (3.84e-2)" "unprognostic (3.38e-2)" "unprognostic (4.63e-2)" "unprognostic (7.51e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (1.83e-1)" "unprognostic (1.14e-2)" "unprognostic (2.45e-1)" "unprognostic (3.69e-2)" "unprognostic (2.00e-2)" "unprognostic (2.25e-3)" "unprognostic (2.60e-3)" "unprognostic (1.44e-3)" "unprognostic (7.93e-2)" "unprognostic (4.26e-2)" "unprognostic (1.13e-1)" "unprognostic (2.66e-2)" "unprognostic (1.12e-1)" "unprognostic (1.90e-2)" "unprognostic (1.80e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.57e-1)" "unprognostic (3.99e-2)" "unprognostic (2.15e-2)" "unprognostic (1.48e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (7.15e-2)" MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 25.3" "Cell type enhanced" "Detected in some" "B-cells: 41.3;cDC: 44.2;Innate lymphoid cells: 26.7;Macrophages: 29.7;Megakaryocyte-Erythroid progenitors: 24.1;Monocyte progenitors: 98.6;monocytes: 154.3;Neutrophil progenitors: 47.6;Neutrophils: 30.6;NK-cells: 69.0;T-cells: 60.9;Thymocytes: 53.4" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 154.3;Neutrophils: 47.6;NK-cells: 69.0;T-cells: 60.9" "Cell type enriched" "Detected in some" 49 "leukocyte: 72.2" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 16.5" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 15 "Leukemia: 88.2;lymphoma: 96.1" "Adipose subcutaneous - T-cells, Breast - T-cells, Kidney - T-cells, Prostate - T-cells, Spleen - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" "B-cells: 105312649.2;Neutrophils: 92353576.9;T-cells: 110465789.0" "Tissue enriched" "Detected in many" "lymphoid tissue: 96043676.6" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 37000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Plasma membrane" Nucleoplasm "HPA021252: " "unprognostic (3.21e-2)" "unprognostic (1.22e-1)" "unprognostic (2.80e-2)" "unprognostic (2.10e-3)" "unprognostic (2.21e-1)" "unprognostic (4.31e-1)" "unprognostic (2.97e-3)" "unprognostic (2.68e-1)" "potential prognostic favorable (5.46e-4)" "unprognostic (1.93e-3)" "unprognostic (2.31e-1)" "unprognostic (1.45e-1)" "unprognostic (3.70e-2)" "unprognostic (2.24e-1)" "unprognostic (8.57e-2)" "unprognostic (8.25e-3)" "unprognostic (2.75e-1)" "unprognostic (8.48e-2)" "unprognostic (4.98e-2)" "unprognostic (2.82e-2)" "unprognostic (4.46e-3)" "unprognostic (8.50e-2)" "unprognostic (3.41e-2)" "unprognostic (9.33e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-1)" "unprognostic (2.85e-3)" "unprognostic (1.90e-1)" MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934229-26212532 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "retina: 14.3;testis: 5.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 136.6;Early spermatids: 249.7;Ependymal cells: 129.1;Gonadotrophs: 110.7;Late primary spermatocytes: 129.1;Late spermatids: 96.4;Müller glia: 475.7;Pancreatic islet cells: 263.1;Vascular smooth muscle cells: 75.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 129.1;Glial cells: 475.7;Pancreatic islet cells: 263.1;Spermatogenic cell types: 249.7" "Group enriched" "Detected in many" 4 "ependymal cell: 122.2;medium spiny neuron: 99.2;midbrain-derived inhibitory: 61.9;vascular associated smooth muscle cell: 141.9" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3.5;Kidney Renal Clear Cell Carcinoma (TCGA): 3.1" "Region enhanced" "Detected in some" "basal ganglia: 3.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 3.5" "Adipose subcutaneous - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Cluster 42: Retina - Visual perception" "Cluster 33: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (4.96e-2)" "unprognostic (9.57e-3)" "unprognostic (3.03e-2)" "potential prognostic favorable (1.73e-4)" "unprognostic (1.51e-2)" "unprognostic (9.28e-2)" "unprognostic (4.34e-2)" "potential prognostic unfavorable (8.57e-4)" "unprognostic (3.52e-2)" MYO6 "DFNA22, DFNB37, KIAA0389" ENSG00000196586 "Myosin VI" Q9UM54 6 75749201-75919537 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Hearing, Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Cardiomyopathy, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1170.1;Esophageal apical cells: 1109.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 1109.3;Glandular cells: 1170.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 5.4;MAIT T-cell: 3.0;memory CD4 T-cell: 1.7;memory CD8 T-cell: 3.1;naive CD8 T-cell: 3.0;NK-cell: 2.9" "Group enriched" "Detected in many" 7 "NK-cells: 2.9;T-cells: 5.4" "Cancer enhanced" "Detected in all" "prostate cancer: 146.4" "Adipose visceral - Endothelial cells, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 124598138.1;Proximal tubules: 175013072.0" "Low tissue specificity" "Detected in many" "CAB010762, HPA035482, HPA035483" Enhanced Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 11: Neuronal - Sensory perception" "Cluster 51: Secretory epithelial cells - Mixed function" 90 Nucleoplasm "CAB010762: , HPA035482: , HPA035483: " "unprognostic (2.75e-2)" "unprognostic (6.80e-3)" "unprognostic (1.70e-1)" "potential prognostic unfavorable (4.32e-4)" "unprognostic (9.87e-3)" "unprognostic (5.96e-2)" "unprognostic (3.16e-2)" "unprognostic (1.21e-1)" "unprognostic (4.55e-3)" "unprognostic (4.49e-2)" "validated prognostic favorable (2.23e-12)" "validated prognostic favorable (7.91e-4)" "unprognostic (4.30e-3)" "unprognostic (5.12e-2)" "unprognostic (1.52e-2)" "potential prognostic favorable (5.40e-4)" "unprognostic (3.92e-2)" "unprognostic (9.76e-3)" "unprognostic (4.55e-2)" "unprognostic (2.22e-1)" "unprognostic (2.00e-2)" "unprognostic (1.04e-1)" "unprognostic (1.48e-1)" "unprognostic (5.60e-2)" "unprognostic (5.16e-3)" "unprognostic (2.52e-1)" "unprognostic (9.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-1)" "unprognostic (1.94e-1)" "unprognostic (8.73e-2)" MYOD1 "bHLHc1, MYF3, MYOD, PUM" ENSG00000129152 "Myogenic differentiation 1" P15172 11 17719571-17722136 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skeletal muscle: 34.4" "Group enriched" "Detected in some" 8 "Myonuclei: 16.9;Myosatellite cells: 40.3;Thymic myoid cells: 10.9" "Group enriched" "Detected in some" 8 "Myocytes: 16.9;Stem cells: 40.3;Stromal cells: 10.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 65 "Sarcoma: 76.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055436, HPA078647" Enhanced Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 39 Nucleoplasm "HPA055436: , HPA078647: " "unprognostic (3.82e-1)" "unprognostic (1.23e-1)" MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 1114.0;Endometrial secretory cells: 712.1;Prostatic hillock cells: 676.7;Urothelial cells: 1157.3" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 1157.3;Glandular cells: 1114.0" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 264.4;choroid plexus epithelial cell: 346.6;endothelial cell: 251.4;pericyte: 248.4;vascular associated smooth muscle cell: 224.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 78.3" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.7" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.7" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 228661161.8;Smooth muscle cells: 289638377.6" "Low tissue specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Centriolar satellite,Basal body" NA NA 62000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 8: Immune cells - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 5 "Vesicles, Plasma membrane, Centriolar satellite" "Primary cilium, Primary cilium tip, Basal body" "HPA014245: " "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (1.25e-1)" "unprognostic (1.34e-1)" "unprognostic (3.56e-1)" "unprognostic (3.64e-2)" "unprognostic (1.12e-1)" "unprognostic (6.23e-3)" "unprognostic (9.08e-2)" "unprognostic (4.73e-1)" "potential prognostic favorable (4.25e-5)" "unprognostic (1.51e-1)" "unprognostic (1.38e-1)" "unprognostic (2.67e-2)" "unprognostic (1.89e-1)" "unprognostic (5.30e-3)" "unprognostic (4.18e-2)" "unprognostic (2.64e-2)" "unprognostic (2.76e-3)" "unprognostic (6.93e-3)" "unprognostic (4.41e-3)" "potential prognostic unfavorable (4.95e-4)" "unprognostic (2.69e-2)" "unprognostic (1.37e-1)" "unprognostic (6.53e-2)" "unprognostic (7.82e-2)" "unprognostic (3.01e-2)" "unprognostic (3.40e-1)" "unprognostic (4.88e-3)" "unprognostic (5.23e-2)" "unprognostic (4.34e-3)" MYOG "bHLHc3, MYF4" ENSG00000122180 Myogenin P15173 1 203083129-203086012 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "skeletal muscle: 98.4;tongue: 43.5" "Group enriched" "Detected in some" 53 "Myonuclei: 31.8;Thymic myoid cells: 53.0" "Group enriched" "Detected in some" 53 "Myocytes: 31.8;Stromal cells: 53.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Head and Neck Squamous Cell Carcinoma (TCGA): 6.2;Testicular Germ Cell Tumor (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 61 "Sarcoma: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA028336 Supported Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 36 Nucleoplasm "HPA028336: " "unprognostic (3.06e-3)" "unprognostic (7.33e-1)" MYOM3 FLJ35961 ENSG00000142661 "Myomesin 3" Q5VTT5 1 24056035-24112135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "heart muscle: 209.7;skeletal muscle: 308.7;tongue: 238.9" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 227.0;Myonuclei: 685.8;Thymic myoid cells: 172.7" "Group enriched" "Detected in many" 5 "Myocytes: 685.8;Stromal cells: 172.7" "Cell type enhanced" "Detected in single" "ependymal cell: 1.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 34.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "colorectal cancer: 3.9;Kidney cancer: 8.9;Rhabdoid: 9.5" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skeletal muscle - Skeletal myocytes, Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1051262718.4;Skeletal myofibers: 2377473452.8" "Group enriched" "Detected in some" "heart muscle: 205988592.4;skeletal muscle: 528776612.7" "HPA028132, HPA028340" Approved "Golgi apparatus,Vesicles,Cytokinetic bridge" Yes No 750000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" Vesicles "Golgi apparatus, Cytokinetic bridge" "HPA028132: , HPA028340: " "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (1.11e-1)" "unprognostic (5.07e-2)" "unprognostic (8.46e-2)" "validated prognostic favorable (1.01e-4)" "validated prognostic favorable (2.34e-5)" "potential prognostic favorable (2.20e-4)" "unprognostic (1.05e-3)" "unprognostic (1.01e-2)" "unprognostic (3.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.15e-2)" "unprognostic (2.68e-2)" "unprognostic (2.42e-2)" MYPN MYOP ENSG00000138347 Myopalladin Q86TC9 10 68087897-68212017 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 64.0;skeletal muscle: 269.9;tongue: 171.2" "Cell type enriched" "Detected in many" 4 "Myonuclei: 2111.1" "Cell type enriched" "Detected in many" 6 "Myocytes: 2111.1" "Cell type enriched" "Detected in some" 7 "hippocampal CA4: 25.8" "Cancer enhanced" "Detected in single" "Head and Neck Squamous Cell Carcinoma (TCGA): 1.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 27 "NK-cell: 1.4;plasmacytoid DC: 4.4" "Group enriched" "Detected in many" 27 "dendritic cells: 4.4;NK-cells: 1.4" "Cancer enriched" "Detected in many" 5 "Adrenocortical cancer: 85.1" "Skeletal muscle - Skeletal myocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" "Capillaries: 29866656.3;Cardiomyocytes: 44271041.5;Skeletal myofibers: 103280786.0" "Group enriched" "Detected in some" 874530 "heart muscle: 53491498.1;skeletal muscle: 121414481.6" "HPA036299, HPA061494" Enhanced Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 2 Nucleoplasm "Vesicles, Cytosol" "HPA036299: , HPA061494: " "unprognostic (1.19e-2)" "unprognostic (2.20e-1)" MYSM1 KIAA1915 ENSG00000162601 "Myb like, SWIRM and MPN domains 1" Q5VVJ2 1 58643440-58700090 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Immunity, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, DNA-binding, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 16490537.4" "Tissue enriched" "Detected in single" 1106 "lymphoid tissue: 110632.3" "HPA054291, HPA057306" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 7 Nucleoplasm Nucleoli "HPA054291: , HPA057306: " "unprognostic (8.15e-3)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.79e-3)" "unprognostic (2.42e-1)" "unprognostic (1.47e-2)" "unprognostic (3.98e-2)" "unprognostic (2.68e-1)" "potential prognostic favorable (7.82e-4)" "unprognostic (3.63e-1)" "unprognostic (1.97e-1)" "unprognostic (4.67e-2)" "potential prognostic favorable (5.74e-4)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (2.23e-2)" "unprognostic (2.29e-3)" "unprognostic (3.52e-2)" "unprognostic (1.87e-3)" "unprognostic (3.42e-2)" "unprognostic (5.66e-2)" "unprognostic (3.31e-1)" "unprognostic (2.62e-1)" "unprognostic (2.31e-2)" "unprognostic (2.89e-2)" "unprognostic (8.11e-2)" "unprognostic (2.03e-1)" "unprognostic (8.76e-3)" "unprognostic (1.15e-1)" "unprognostic (2.95e-1)" "unprognostic (2.23e-2)" "unprognostic (1.53e-1)" MYT1 "MTF1, MYTI, NZF2, PLPB1, ZC2H2C1, ZC2HC4A" ENSG00000196132 "Myelin transcription factor 1" Q01538 20 64102394-64242253 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 32.9" "Cell type enriched" "Detected in some" 9 "Oligodendrocyte progenitor cells: 238.7" "Cell type enriched" "Detected in some" 9 "Glial cells: 238.7" "Cell type enriched" "Detected in many" 4 "oligodendrocyte precursor cell: 284.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.2" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Spleen - B-cells (Spleen), Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 30.2" "Cell type enriched" "Detected in single" 2518 "Macrophages: 251759.6" "Not detected" "Not detected" "HPA006303, HPA067092" Uncertain Enhanced Nucleoplasm,Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 Nucleoplasm Cytosol "HPA006303: , HPA067092: " "unprognostic (1.15e-2)" "unprognostic (1.49e-1)" "unprognostic (9.85e-2)" "potential prognostic favorable (4.11e-4)" "unprognostic (4.06e-2)" MZB1 "HSPC190, MEDA-7, MGC29506, PACAP, pERp1" ENSG00000170476 "Marginal zone B and B1 cell specific protein" Q8WU39 5 139387467-139390081 "Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 84.5;lymphoid tissue: 214.9" "Cell type enriched" "Detected in many" 8 "Plasma cells: 4016.9" "Cell type enriched" "Detected in many" 8 "Plasma cells: 4016.9" "Group enriched" "Detected in some" 10 "ependymal cell: 2.5;leukocyte: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 5 "memory B-cell: 160.8;plasmacytoid DC: 570.5" "Group enriched" "Detected in many" 115 "B-cells: 160.8;dendritic cells: 570.5" "Cancer enriched" "Detected in some" 5 "Myeloma: 759.0" "Adipose subcutaneous - Plasma cells, Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Colon - Plasma cells, Heart muscle - Plasma cells, Kidney - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Pituitary gland - Plasma cells, Skin - Plasma cells, Spleen - Plasma cells, Stomach - Plasma cells, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" "Alveolar cell types: 28896444.8;B-cells: 16091762.0;Macrophages: 10098432.4;Neutrophils: 27841737.4;T-cells: 21217244.6" "Tissue enhanced" "Detected in many" "bone marrow: 318287216.7;salivary gland: 276300505.1" "HPA043745, HPA052694" Enhanced Approved "Golgi apparatus" "Secreted to blood" Other NA NA 260000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 6 "Golgi apparatus" "HPA043745: , HPA052694: " "unprognostic (1.08e-1)" "potential prognostic favorable (5.58e-4)" "unprognostic (1.29e-3)" "unprognostic (1.24e-1)" "unprognostic (3.48e-1)" "potential prognostic favorable (1.29e-4)" "unprognostic (2.68e-3)" "unprognostic (4.10e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (7.43e-2)" "unprognostic (1.77e-2)" "unprognostic (2.53e-2)" "unprognostic (4.01e-3)" "unprognostic (2.00e-1)" "unprognostic (6.01e-2)" "unprognostic (5.00e-3)" "unprognostic (4.17e-2)" "unprognostic (3.36e-1)" "unprognostic (2.23e-2)" "unprognostic (1.20e-1)" "unprognostic (1.98e-2)" "unprognostic (7.35e-2)" "unprognostic (8.93e-2)" "unprognostic (6.28e-2)" "unprognostic (5.11e-1)" "unprognostic (6.90e-2)" "unprognostic (2.54e-1)" N4BP1 ENSG00000102921 "NEDD4 binding protein 1" O75113 16 48538726-48620148 "Predicted intracellular proteins" "Immunity, Innate immunity" "Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Neutrophils: 2433.8" "Cell type enriched" "Detected in many" 5 "Neutrophils: 2433.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 8.5" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.5" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA040849, HPA041080" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 58: Skin - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 8 "Nucleoli fibrillar center" "Nucleoplasm, Cytosol" "HPA040849: , HPA041080: " "unprognostic (9.16e-2)" "unprognostic (1.23e-1)" "unprognostic (1.54e-1)" "unprognostic (5.59e-2)" "unprognostic (2.04e-1)" "unprognostic (1.59e-1)" "unprognostic (2.40e-1)" "unprognostic (9.30e-2)" "unprognostic (2.62e-1)" "unprognostic (5.49e-3)" "potential prognostic favorable (1.97e-7)" "unprognostic (4.66e-2)" "unprognostic (2.28e-3)" "unprognostic (1.50e-2)" "unprognostic (7.93e-2)" "unprognostic (2.47e-1)" "unprognostic (6.66e-2)" "unprognostic (1.65e-1)" "unprognostic (1.52e-1)" "unprognostic (9.51e-2)" "unprognostic (2.09e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.88e-5)" "unprognostic (2.43e-1)" "unprognostic (2.13e-2)" "unprognostic (6.37e-2)" "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (7.39e-2)" "unprognostic (1.09e-1)" "unprognostic (2.12e-2)" N4BP2 B3BP ENSG00000078177 "NEDD4 binding protein 2" Q86UW6 4 40056797-40158252 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.5" "Cell type enhanced" "Detected in many" "Thymocytes: 197.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 448367.2" "Not detected" "Not detected" "HPA036770, HPA042607, HPA072549" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 12 Nucleoplasm "Plasma membrane, Cytosol" "HPA036770: , HPA042607: , HPA072549: " "unprognostic (2.20e-2)" "unprognostic (1.65e-1)" "unprognostic (6.71e-2)" "unprognostic (3.46e-2)" "potential prognostic favorable (6.39e-5)" "unprognostic (3.63e-1)" "unprognostic (1.50e-1)" "unprognostic (3.12e-2)" "unprognostic (1.26e-2)" "unprognostic (1.40e-2)" "unprognostic (2.04e-1)" "unprognostic (2.01e-2)" "unprognostic (8.94e-2)" "unprognostic (2.27e-1)" "unprognostic (5.11e-2)" "unprognostic (7.99e-3)" "unprognostic (2.67e-1)" "unprognostic (9.14e-2)" "unprognostic (5.92e-2)" "unprognostic (1.22e-1)" "unprognostic (1.33e-1)" "unprognostic (9.26e-3)" "potential prognostic unfavorable (1.19e-4)" "unprognostic (3.42e-2)" "unprognostic (2.83e-1)" "unprognostic (7.50e-2)" "unprognostic (1.66e-2)" "unprognostic (2.00e-1)" "unprognostic (2.96e-2)" "unprognostic (1.02e-2)" "unprognostic (5.30e-2)" N6AMT1 "C21orf127, HEMK2, KMT9, MTQ2, N6AMT, PRED28, PrmC" ENSG00000156239 "N-6 adenine-specific DNA methyltransferase 1" Q9Y5N5 21 28872191-28885371 "Predicted intracellular proteins" "Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "bone marrow: 862642.0" "CAB034133, CAB034135, HPA059242" Approved Approved Nucleoplasm,Centrosome Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm Centrosome "CAB034133: , CAB034135: , HPA059242: " "unprognostic (2.83e-2)" "unprognostic (1.14e-3)" "unprognostic (1.86e-1)" "unprognostic (6.42e-2)" "unprognostic (7.01e-2)" "unprognostic (8.83e-2)" "unprognostic (1.52e-1)" "unprognostic (2.38e-2)" "unprognostic (2.83e-1)" "unprognostic (6.66e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (9.10e-6)" "unprognostic (3.09e-2)" "unprognostic (3.73e-3)" "unprognostic (8.06e-2)" "unprognostic (8.37e-3)" "unprognostic (7.18e-2)" "unprognostic (7.22e-2)" "unprognostic (2.51e-2)" "unprognostic (3.05e-2)" "unprognostic (1.21e-1)" "unprognostic (1.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (1.40e-4)" "unprognostic (7.13e-2)" "unprognostic (2.66e-1)" "unprognostic (4.47e-3)" "unprognostic (2.62e-1)" "unprognostic (1.95e-1)" "unprognostic (5.89e-3)" NAA10 "ARD1, ARD1A, DXS707, TE2" ENSG00000102030 "N-alpha-acetyltransferase 10, NatA catalytic subunit" P41227 X 153929225-153935080 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 92.7" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "CAB006269, HPA030711" Supported Supported Nucleoli,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 76 Cytosol Nucleoli "CAB006269: , HPA030711: " "unprognostic (3.77e-2)" "unprognostic (2.54e-2)" "unprognostic (1.84e-1)" "unprognostic (2.07e-1)" "unprognostic (1.41e-1)" "unprognostic (1.67e-1)" "unprognostic (8.10e-2)" "unprognostic (1.91e-3)" "unprognostic (5.88e-3)" "unprognostic (1.08e-2)" "unprognostic (1.09e-1)" "unprognostic (1.37e-3)" "unprognostic (8.45e-3)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (1.32e-3)" "unprognostic (9.50e-3)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.16e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (3.89e-4)" "unprognostic (7.59e-2)" "unprognostic (2.13e-1)" "unprognostic (9.72e-2)" "unprognostic (4.58e-1)" "unprognostic (1.68e-1)" "unprognostic (2.48e-1)" "unprognostic (4.05e-2)" "unprognostic (2.04e-2)" "unprognostic (4.12e-2)" "unprognostic (1.49e-1)" NAA11 "ARD1B, ARD2, hARD2" ENSG00000156269 "N-alpha-acetyltransferase 11, NatA catalytic subunit" Q9BSU3 4 79225694-79326061 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "placenta: 3.9;testis: 5.8" "Cell type enhanced" "Detected in many" "Astrocytes: 26.0;Cardiomyocytes: 25.8;Cytotrophoblasts: 56.0;Differentiating spermatogonia: 21.9;Early primary spermatocytes: 42.0;Early spermatids: 43.8;Ependymal cells: 36.1;Epicardial cells: 52.3;Extravillous trophoblasts: 29.2;Fibro-adipogenic progenitors: 43.6;Fibroblasts: 30.9;Late primary spermatocytes: 67.6;Late spermatids: 40.4;Migrating cytotrophoblasts: 35.6;Syncytiotrophoblasts: 31.9;Undifferentiated spermatogonia: 26.0;Vascular smooth muscle cells: 33.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 52.3;Ciliated cells: 36.1;Fibro-adipogenic progenitors: 43.6;Mural cells: 33.9;Spermatogenic cell types: 67.6;Trophoblast cells: 56.0" "Group enriched" "Detected in many" 7 "astrocyte: 81.9;ependymal cell: 71.2;fibroblast: 42.7" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 1.2;Testicular Germ Cell Tumor (TCGA): 4.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 7.0;thyroid cancer: 7.2" "Testis - Early spermatids" "Not detected" "Not detected" "Cell type enriched" "Detected in many" "Capillaries: 730644.1" "Tissue enriched" "Detected in single" 39 "lymphoid tissue: 3863.7" HPA035922 Approved Supported "Nucleoplasm,Golgi apparatus,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 28: Astrocytes - Homeostasis & neuron support" 15 "Golgi apparatus, Centrosome, Cytosol" "Nucleoplasm, Primary cilium, Basal body" "HPA035922: " "unprognostic (2.73e-1)" "unprognostic (1.74e-2)" "unprognostic (2.41e-1)" NAA15 "FLJ13340, NARG1, NATH, TBDN100" ENSG00000164134 "N-alpha-acetyltransferase 15, NatA auxiliary subunit" Q9BXJ9 4 139301446-139420033 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA023589, HPA050661" Approved Approved "Nuclear bodies,Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Cytosol" Yes NA 59000 "Cluster 14: Non-specific - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 18 Cytosol "Nuclear bodies, Vesicles, Microtubules, Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA023589: , HPA050661: " "unprognostic (2.53e-1)" "unprognostic (3.57e-2)" "unprognostic (2.73e-1)" "unprognostic (2.36e-3)" "unprognostic (7.12e-3)" "unprognostic (1.67e-1)" "unprognostic (1.99e-1)" "unprognostic (1.91e-1)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (2.50e-4)" "potential prognostic favorable (1.09e-4)" "unprognostic (4.53e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (2.30e-6)" "unprognostic (7.14e-3)" "unprognostic (2.38e-3)" "unprognostic (6.67e-3)" "unprognostic (4.37e-1)" "unprognostic (2.67e-1)" "unprognostic (3.20e-2)" "unprognostic (1.26e-3)" "unprognostic (4.84e-3)" "unprognostic (6.11e-3)" "unprognostic (1.33e-2)" "unprognostic (7.33e-2)" "unprognostic (3.93e-2)" "unprognostic (4.26e-2)" "unprognostic (1.85e-1)" "unprognostic (1.68e-1)" "unprognostic (4.53e-3)" "unprognostic (4.44e-3)" NAA20 "dJ1002M8.1, NAT3, NAT5" ENSG00000173418 "N-alpha-acetyltransferase 20, NatB catalytic subunit" P61599 20 20017310-20033655 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1708.5;Esophageal basal cells: 394.4;Esophageal suprabasal cells: 780.6;Hofbauer cells: 430.5;Late primary spermatocytes: 858.2" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1708.5;Spermatogenic cell types: 858.2;Suprabasal cells: 780.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 8193452.2" "Group enriched" "Detected in many" "cerebral cortex: 6214701.4;lymphoid tissue: 4519640.8" HPA063344 Supported Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 21: Non-specific - Metabolism" "Cluster 62: Non-specific - Plasma proteins" "Cluster 85: Squamous epithelial cells - Keratinization" 5 Cytosol "HPA063344: " "unprognostic (1.37e-2)" "unprognostic (5.70e-3)" "unprognostic (2.14e-1)" "unprognostic (4.27e-2)" "unprognostic (1.76e-1)" "unprognostic (6.22e-2)" "unprognostic (4.48e-3)" "unprognostic (3.20e-2)" "unprognostic (1.57e-3)" "unprognostic (1.89e-1)" "potential prognostic favorable (1.30e-4)" "unprognostic (1.53e-1)" "unprognostic (6.61e-2)" "unprognostic (9.20e-3)" "unprognostic (1.42e-3)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (3.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.79e-1)" "unprognostic (1.50e-1)" "unprognostic (1.61e-1)" "unprognostic (4.06e-2)" "unprognostic (6.05e-2)" "unprognostic (2.43e-2)" "unprognostic (4.58e-1)" "unprognostic (3.41e-2)" "unprognostic (3.19e-1)" "unprognostic (6.28e-2)" "unprognostic (4.12e-2)" NAA25 "C12orf30, FLJ13089" ENSG00000111300 "N-alpha-acetyltransferase 25, NatB auxiliary subunit" Q14CX7 12 112026689-112108796 "Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 255.7;Cone photoreceptor cells: 242.2;Myonuclei: 248.9;Retinal pigment epithelial cells: 298.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 3204858.6" "Group enriched" "Detected in many" "fallopian tube: 1447862.0;lymphoid tissue: 1646847.1;Stomach: 3352518.4" HPA039322 Approved Supported "Golgi apparatus,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 3 "Golgi apparatus, Cytosol" "HPA039322: " "unprognostic (2.86e-1)" "unprognostic (9.31e-3)" "unprognostic (1.35e-2)" "unprognostic (1.49e-2)" "unprognostic (1.05e-1)" "unprognostic (4.53e-2)" "unprognostic (1.63e-1)" "unprognostic (2.96e-2)" "unprognostic (8.02e-2)" "unprognostic (3.91e-2)" "unprognostic (1.04e-2)" "unprognostic (2.69e-3)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.29e-5)" "unprognostic (1.26e-2)" "unprognostic (3.62e-3)" "unprognostic (3.22e-3)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (1.28e-1)" "unprognostic (2.37e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-3)" "unprognostic (1.31e-2)" "potential prognostic favorable (1.50e-4)" "unprognostic (9.06e-2)" "unprognostic (1.38e-1)" "unprognostic (7.26e-2)" "unprognostic (2.01e-1)" "unprognostic (5.89e-2)" "unprognostic (5.52e-2)" NAA38 "LSMD1, MGC14151, PFAAP2" ENSG00000183011 "N-alpha-acetyltransferase 38, NatC auxiliary subunit" Q9BRA0 17 7856685-7885238 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 803.1;Epicardial cells: 991.5;Late spermatids: 2248.9;Megakaryocytes: 3078.4" "Cell type enhanced" "Detected in all" "Megakaryocytes: 3078.4;Spermatogenic cell types: 2248.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2471 "Collecting ducts: 134914.0;Neurons: 197140.5;Oocytes: 409272.8" "Tissue enriched" "Detected in many" "ovary: 6556159.2" HPA059189 Supported Nucleoplasm No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 47: Platelets - Hemostasis" 5 Nucleoplasm "HPA059189: " "unprognostic (1.32e-1)" "unprognostic (2.13e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (6.80e-5)" "unprognostic (1.37e-1)" "unprognostic (4.94e-2)" "unprognostic (2.99e-2)" "unprognostic (8.61e-2)" "unprognostic (1.08e-1)" "unprognostic (1.46e-3)" "unprognostic (1.45e-1)" "unprognostic (1.90e-2)" "unprognostic (6.18e-2)" "unprognostic (9.36e-2)" "unprognostic (1.21e-3)" "unprognostic (2.26e-2)" "unprognostic (2.34e-1)" "unprognostic (4.63e-2)" "unprognostic (3.35e-1)" "unprognostic (1.86e-3)" "unprognostic (2.30e-1)" "potential prognostic favorable (7.81e-4)" "unprognostic (8.14e-2)" "unprognostic (1.15e-1)" "unprognostic (3.35e-1)" "unprognostic (1.99e-2)" "unprognostic (8.53e-2)" "unprognostic (1.73e-1)" "unprognostic (5.54e-2)" "unprognostic (1.53e-1)" "unprognostic (1.75e-1)" NAA40 "FLJ13848, NAT11" ENSG00000110583 "N-alpha-acetyltransferase 40, NatD catalytic subunit" Q86UY6 11 63938959-63957319 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 195.3;Retinal horizontal cells: 106.2" "Cell type enhanced" "Detected in many" "Neuronal cells: 106.2;Spermatogenic cell types: 195.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 725609.0" "Group enriched" "Detected in many" "lymphoid tissue: 616832.5;salivary gland: 186598.6;Stomach: 237087.7" "HPA037816, HPA056142" Uncertain Supported "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 31 Nucleoplasm "Centriolar satellite, Cytosol" "HPA037816: , HPA056142: " "unprognostic (9.02e-2)" "unprognostic (9.22e-3)" "unprognostic (2.40e-2)" "unprognostic (9.26e-2)" "unprognostic (7.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.65e-1)" "unprognostic (1.29e-3)" "unprognostic (7.76e-2)" "unprognostic (3.76e-2)" "unprognostic (3.72e-1)" "unprognostic (2.56e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.03e-7)" "unprognostic (4.60e-2)" "unprognostic (6.62e-2)" "unprognostic (2.45e-2)" "unprognostic (3.60e-2)" "unprognostic (2.32e-2)" "unprognostic (4.01e-1)" "unprognostic (2.00e-1)" "unprognostic (1.59e-1)" "unprognostic (3.58e-3)" "unprognostic (3.99e-2)" "unprognostic (1.38e-2)" "unprognostic (8.98e-2)" "unprognostic (6.86e-3)" "unprognostic (3.46e-3)" "unprognostic (1.64e-1)" "unprognostic (7.08e-2)" "unprognostic (2.62e-1)" NACAD KIAA0363 ENSG00000136274 "NAC alpha domain containing" O15069 7 45080437-45088969 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 63.4;pituitary gland: 22.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Brain inhibitory neurons: 9.4;Gonadotrophs: 15.1;Lactotrophs: 12.2;Oligodendrocytes: 40.2;Other brain neurons: 18.1;Peritubular myoid cells: 11.1;Retinal horizontal cells: 14.0;Thyrotrophs: 9.5" "Cell type enhanced" "Detected in many" "Glial cells: 40.2;Neuronal cells: 18.1;Pituitary endocrine cells: 15.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 49.7" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 25.7;Testicular Germ Cell Tumor (TCGA): 30.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Neuroblastoma: 25.4" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Microglia and Neuropil: 3861354.3;Neurons: 13591246.3" "Tissue enriched" "Detected in some" "cerebral cortex: 18951286.9" "HPA020981, HPA079208" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 3 Cytosol Nucleoplasm "HPA020981: , HPA079208: " "unprognostic (1.02e-2)" "unprognostic (1.34e-3)" "unprognostic (4.30e-1)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (6.25e-4)" "unprognostic (2.21e-2)" "unprognostic (2.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (7.04e-2)" "unprognostic (1.63e-2)" "unprognostic (6.97e-2)" "unprognostic (1.10e-1)" "unprognostic (3.46e-2)" "unprognostic (1.07e-1)" "unprognostic (3.98e-2)" "unprognostic (6.47e-2)" "unprognostic (4.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.47e-2)" "unprognostic (2.53e-2)" "unprognostic (1.27e-2)" "unprognostic (3.51e-2)" "unprognostic (2.88e-1)" "unprognostic (1.18e-2)" NACC1 "BEND8, BTBD14B, BTBD30, NAC-1, NAC1" ENSG00000160877 "Nucleus accumbens associated 1" Q96RE7 19 13116862-13141147 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 7774033.9;Neurons: 13046655.1" "Tissue enriched" "Detected in many" "lymphoid tissue: 5833175.3" "HPA021238, HPA062245, CAB069927" Enhanced Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 81: Alveolar cells - Lung function" 27 Nucleoplasm "Vesicles, Cytosol" "CAB069927: , HPA021238: , HPA062245: " "unprognostic (5.84e-2)" "unprognostic (3.05e-2)" "unprognostic (3.39e-1)" "unprognostic (5.41e-2)" "unprognostic (2.24e-2)" "unprognostic (1.14e-1)" "unprognostic (4.28e-1)" "unprognostic (1.69e-1)" "unprognostic (1.61e-1)" "unprognostic (2.49e-2)" "unprognostic (5.90e-2)" "potential prognostic unfavorable (9.36e-4)" "unprognostic (2.15e-1)" "unprognostic (1.34e-2)" "unprognostic (2.60e-2)" "unprognostic (3.36e-3)" "unprognostic (1.92e-2)" "unprognostic (1.53e-1)" "unprognostic (4.17e-2)" "unprognostic (2.51e-1)" "unprognostic (8.21e-2)" "unprognostic (1.91e-2)" "unprognostic (1.32e-1)" "unprognostic (3.72e-2)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (7.69e-3)" "unprognostic (8.23e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-1)" "unprognostic (3.03e-2)" NADK FLJ13052 ENSG00000008130 "NAD kinase" O95544 1 1751232-1780457 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Neutrophil progenitors: 191.4;Neutrophils: 342.4" "Cell type enriched" "Detected in many" 5 "Neutrophils: 342.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 507.6" "Group enriched" "Detected in all" 7 "granulocytes: 507.6;monocytes: 163.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Macrophages: 3243683.5" "Tissue enhanced" "Detected in many" "intestine: 5380250.0" "HPA048909, HPA053368" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 21 Nucleoplasm Cytosol "HPA048909: , HPA053368: " "unprognostic (4.01e-2)" "unprognostic (1.38e-1)" "unprognostic (2.10e-2)" "unprognostic (5.56e-2)" "unprognostic (2.91e-2)" "unprognostic (8.04e-3)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "unprognostic (3.31e-2)" "unprognostic (1.82e-1)" "unprognostic (1.07e-1)" "unprognostic (8.26e-2)" "unprognostic (8.86e-3)" "unprognostic (2.19e-1)" "unprognostic (6.65e-3)" "unprognostic (1.87e-1)" "unprognostic (4.74e-1)" "unprognostic (5.72e-2)" "unprognostic (3.71e-1)" "unprognostic (6.87e-2)" "potential prognostic favorable (1.61e-4)" "unprognostic (3.37e-1)" "unprognostic (2.13e-1)" "unprognostic (4.16e-1)" "unprognostic (2.07e-1)" "unprognostic (2.17e-1)" "unprognostic (2.37e-2)" "unprognostic (1.65e-1)" "unprognostic (2.25e-1)" "unprognostic (1.63e-2)" "unprognostic (3.10e-1)" NAGS "AGAS, ARGA, NAT7" ENSG00000161653 "N-acetylglutamate synthase" Q8N159 17 44004622-44009068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Urea cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 14.9;liver: 49.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.8;Enterocytes: 43.2;Epididymal efferent duct absorptive cells: 15.9;Epididymal principal cells: 13.5;Esophageal apical cells: 15.7;Hepatocytes: 23.8;Late primary spermatocytes: 23.1" "Cell type enhanced" "Detected in many" "Enterocytes: 43.2;Hepatocytes: 23.8;Spermatogenic cell types: 23.1" "Cell type enriched" "Detected in single" 7 "endothelial cell: 6.5" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 18.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Hepatocytes: 23055965.1" "Tissue enriched" "Detected in single" 91796 "liver: 9179593.1" HPA027300 Approved Mitochondria "Intracellular and membrane" Enzyme NA NA "Cluster 77: Intestine - Digestion" "Cluster 24: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 1: Enterocytes - Absorption and Digestion" 5 Mitochondria "HPA027300: " "unprognostic (1.02e-2)" "potential prognostic favorable (4.60e-4)" "unprognostic (9.94e-2)" "unprognostic (2.29e-2)" "unprognostic (9.75e-3)" "unprognostic (3.91e-2)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (3.18e-3)" "unprognostic (5.92e-2)" "unprognostic (1.20e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (6.19e-4)" "unprognostic (7.34e-2)" "unprognostic (2.48e-1)" "potential prognostic favorable (6.90e-4)" "unprognostic (2.43e-1)" "unprognostic (6.09e-3)" "unprognostic (2.73e-3)" "potential prognostic unfavorable (5.35e-5)" "unprognostic (1.95e-2)" "unprognostic (1.49e-2)" "unprognostic (1.53e-1)" "unprognostic (1.81e-1)" "unprognostic (2.03e-1)" "unprognostic (1.73e-1)" "unprognostic (4.05e-1)" NALCN "bA430M15.1, CanIon, VGCNL1" ENSG00000102452 "Sodium leak channel, non-selective" Q8IZF0 13 101053776-101416508 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 15.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 255.3;Astrocytes: 233.4;Bergmann glia: 241.6;Brain excitatory neurons: 331.6;Brain inhibitory neurons: 382.8;Corticotrophs: 326.5;Gonadotrophs: 418.8;Lactotrophs: 453.9;Oligodendrocyte progenitor cells: 440.0;Oligodendrocytes: 606.0;Other brain neurons: 340.3;Pituicytes/FSCs: 377.7;Retinal pigment epithelial cells: 366.6;Somatotrophs: 459.7;Thyrotrophs: 454.0" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 255.3;Glial cells: 606.0;Neuronal cells: 382.8;Pigment cells: 366.6;Pituitary endocrine cells: 459.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 2.5" "Lineage enriched" "Detected in single" 7 "granulocytes: 2.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Skin - Eccrine sweat gland cells, Spleen - Smooth muscle cells, Stomach - Gastric enteroendocrine cells, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2417 "Microglia and Neuropil: 173022.4;Neurons: 310450.1" "Tissue enriched" "Detected in single" 50 "cerebral cortex: 4971.7" "HPA031889, HPA031890, HPA031958" Approved Uncertain "Nucleoli,Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Cytosol" Yes NA "Cluster 32: Basophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 "Microtubules, Primary cilium, Cytosol" "Nucleoli, Plasma membrane, Cytokinetic bridge, Mitotic spindle" "HPA031889: , HPA031890: , HPA031958: " "unprognostic (1.20e-1)" "unprognostic (1.37e-1)" "unprognostic (7.49e-3)" "unprognostic (4.22e-2)" "unprognostic (3.31e-3)" "unprognostic (5.87e-2)" "unprognostic (8.02e-2)" "unprognostic (3.71e-1)" "unprognostic (3.67e-2)" "unprognostic (3.12e-1)" "unprognostic (1.07e-1)" "unprognostic (1.94e-3)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (5.39e-5)" "unprognostic (3.75e-2)" "unprognostic (2.00e-2)" "unprognostic (1.27e-1)" NANOG "FLJ12581, FLJ40451" ENSG00000111704 "Nanog homeobox" Q9H9S0 12 7787794-7799146 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Distal convoluted tubule cells: 3.3;Foveolar cells: 2.7;Loop of henle epithelial cells: 2.1;Papillary tip epithelial cells: 1.5;Parietal cells: 1.8;Podocytes: 1.8;Proximal tubule cells: 2.0;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 1.5;Renal connecting tubule cells: 2.3" "Group enriched" "Detected in some" 4 "Ductal cells: 2.3;Gastric glandular cells: 2.7;Neuronal cells: 2.1;Renal nephron cells: 3.3" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 238 "Testicular Germ Cell Tumor (TCGA): 293.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 1.7" "Group enriched" "Detected in many" 5 "dendritic cells: 1.7;granulocytes: 1.4" "Cancer enriched" "Detected in single" 81 "testis cancer: 23.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB019380, HPA072117, CAB080504, CAB080505" Supported Enhanced Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 10 Nucleoplasm "CAB019380: , CAB080504: , CAB080505: , HPA072117: " "unprognostic (6.34e-2)" "unprognostic (4.36e-2)" "unprognostic (5.15e-2)" "unprognostic (1.76e-1)" "unprognostic (1.40e-1)" NANOGP8 ENSG00000255192 "Nanog homeobox retrogene P8" Q6NSW7 15 35083410-35085295 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Adrenal cortex cells: 3.1;Early spermatids: 1.2;Sertoli cells: 3.4" "Group enriched" "Detected in some" 4 "Adrenal endocrine cells: 3.1;Reproductive supporting cells: 3.4;Spermatogenic cell types: 1.2" "Cancer enriched" "Detected in some" 61 "Testicular Germ Cell Tumor (TCGA): 87.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "testis cancer: 10.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA072117 Supported Nucleoplasm,Vesicles NA NA "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" Nucleoplasm Vesicles "HPA072117: " "unprognostic (1.37e-1)" "unprognostic (6.84e-2)" NANS SAS ENSG00000095380 "N-acetylneuraminate synthase" Q9NR45 9 98056732-98083077 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 289.2;Goblet cells: 310.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 51258327.6" "Tissue enhanced" "Detected in all" "salivary gland: 169348458.9" HPA019223 Approved Enhanced Nucleoplasm No No 290000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 60: Stomach - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 9 Nucleoplasm "HPA019223: " "unprognostic (7.60e-3)" "unprognostic (3.73e-2)" "unprognostic (4.49e-1)" "unprognostic (7.82e-2)" "unprognostic (1.57e-1)" "unprognostic (4.36e-1)" "unprognostic (2.75e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-2)" "unprognostic (1.30e-3)" "unprognostic (8.55e-3)" "unprognostic (2.40e-1)" "unprognostic (1.11e-1)" "validated prognostic unfavorable (4.01e-6)" "validated prognostic unfavorable (8.34e-6)" "unprognostic (1.44e-3)" "unprognostic (2.62e-1)" "unprognostic (2.91e-1)" "unprognostic (2.01e-1)" "unprognostic (6.62e-2)" "unprognostic (1.51e-1)" "unprognostic (1.05e-2)" "unprognostic (2.81e-2)" "unprognostic (1.51e-1)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (2.60e-2)" "unprognostic (4.74e-2)" "unprognostic (3.23e-2)" "unprognostic (1.85e-1)" "unprognostic (1.65e-3)" NAP1L4 NAP2 ENSG00000205531 "Nucleosome assembly protein 1 like 4" Q99733 11 2944431-2992377 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 378.9;Distal convoluted tubule cells: 239.4;Renal collecting duct intercalated cells: 213.8;Renal connecting tubule cells: 188.2" "Cell type enhanced" "Detected in all" "Ciliated cells: 378.9;Renal nephron cells: 239.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" CAB011567 Approved Supported Nucleoplasm NA NA 3800000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 32 Nucleoplasm "CAB011567: " "unprognostic (8.46e-2)" "unprognostic (9.64e-2)" "unprognostic (4.00e-2)" "unprognostic (6.58e-3)" "unprognostic (7.12e-2)" "unprognostic (6.43e-2)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (1.10e-1)" "unprognostic (6.76e-2)" "unprognostic (9.51e-2)" "unprognostic (2.87e-2)" "unprognostic (5.30e-2)" "unprognostic (2.33e-2)" "unprognostic (2.69e-3)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (7.75e-2)" "unprognostic (5.89e-3)" "unprognostic (1.34e-1)" "unprognostic (2.26e-2)" "unprognostic (6.29e-2)" "unprognostic (1.42e-1)" "unprognostic (2.17e-1)" "unprognostic (1.37e-3)" "unprognostic (7.45e-2)" "unprognostic (7.01e-2)" "unprognostic (2.85e-2)" "unprognostic (3.31e-2)" "unprognostic (1.45e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (9.46e-5)" "unprognostic (2.53e-3)" NARS2 "DFNB94, FLJ23441, SLM5" ENSG00000137513 "Asparaginyl-tRNA synthetase 2, mitochondrial" Q96I59 11 78435620-78575194 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Deafness, Disease variant, Leigh syndrome, Non-syndromic deafness, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 342.6" "Cell type enhanced" "Detected in all" "Ciliated cells: 342.6" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 289.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA026793 Supported Supported Nucleoplasm,Mitochondria,Cytosol No No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 16 Mitochondria "Nucleoplasm, Cytosol" "HPA026793: " "unprognostic (2.41e-2)" "unprognostic (7.64e-2)" "unprognostic (1.80e-2)" "unprognostic (4.84e-2)" "unprognostic (9.68e-2)" "unprognostic (1.41e-2)" "unprognostic (6.85e-2)" "unprognostic (2.44e-3)" "unprognostic (4.01e-2)" "potential prognostic unfavorable (2.76e-4)" "potential prognostic favorable (6.47e-5)" "unprognostic (3.57e-1)" "unprognostic (8.17e-3)" "unprognostic (4.65e-2)" "unprognostic (2.48e-2)" "unprognostic (5.45e-2)" "unprognostic (4.02e-2)" "unprognostic (1.65e-1)" "unprognostic (4.95e-2)" "potential prognostic favorable (1.03e-4)" "unprognostic (2.15e-1)" "unprognostic (1.28e-1)" "unprognostic (3.08e-2)" "unprognostic (1.13e-1)" "unprognostic (3.90e-3)" "unprognostic (9.70e-2)" "potential prognostic unfavorable (2.23e-5)" "unprognostic (1.66e-1)" "unprognostic (5.51e-1)" "unprognostic (6.69e-2)" "unprognostic (4.40e-1)" NASP "DKFZp547F162, FLB7527, FLJ31599, FLJ35510, MGC19722, MGC20372, MGC2297, PRO1999" ENSG00000132780 "Nuclear autoantigenic sperm protein" P49321 1 45583846-45618904 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA replication, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Differentiating spermatogonia: 600.2;Early primary spermatocytes: 694.2;Erythrocyte progenitors: 484.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 694.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 386.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 70238824.2;Oocytes: 62517411.7" "Tissue enhanced" "Detected in all" "skeletal muscle: 133084923.8" "HPA028136, HPA030518, HPA030520" Enhanced Enhanced Nucleoplasm NA Yes 320000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 48 Nucleoplasm "HPA028136: , HPA030518: , HPA030520: " "unprognostic (6.05e-2)" "unprognostic (3.33e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (4.38e-1)" "unprognostic (2.09e-1)" "unprognostic (4.08e-2)" "unprognostic (9.42e-3)" "unprognostic (1.39e-2)" "unprognostic (2.19e-2)" "unprognostic (3.08e-1)" "unprognostic (7.80e-2)" "potential prognostic unfavorable (5.02e-7)" "unprognostic (8.61e-3)" "unprognostic (7.38e-3)" "unprognostic (1.02e-2)" "unprognostic (1.03e-2)" "unprognostic (9.49e-3)" "unprognostic (8.47e-2)" "unprognostic (2.23e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-2)" "unprognostic (4.01e-2)" "unprognostic (1.25e-1)" "unprognostic (3.36e-2)" "unprognostic (2.69e-3)" "unprognostic (8.33e-3)" "unprognostic (5.99e-2)" "unprognostic (2.37e-1)" "unprognostic (1.15e-1)" NAT10 "FLJ10774, FLJ12179, hALP, KIAA1709, Kre33, NET43" ENSG00000135372 "N-acetyltransferase 10" Q9H0A0 11 34105617-34147670 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "rRNA processing, tRNA processing" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB035546, HPA057576, HPA071628" Approved Enhanced Nucleoli,Midbody Yes No 54000 "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 88 Nucleoli Midbody "CAB035546: , HPA057576: , HPA071628: " "unprognostic (3.62e-2)" "unprognostic (2.43e-1)" "unprognostic (1.56e-1)" "unprognostic (2.03e-2)" "unprognostic (3.79e-2)" "unprognostic (1.34e-1)" "unprognostic (2.17e-2)" "unprognostic (3.79e-1)" "potential prognostic unfavorable (5.30e-5)" "unprognostic (5.32e-3)" "unprognostic (3.44e-1)" "unprognostic (9.97e-2)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (3.48e-9)" "unprognostic (2.58e-3)" "unprognostic (6.40e-2)" "potential prognostic unfavorable (7.49e-7)" "unprognostic (3.58e-2)" "unprognostic (1.38e-1)" "unprognostic (1.27e-1)" "unprognostic (8.31e-2)" "unprognostic (5.30e-3)" "unprognostic (2.18e-2)" "unprognostic (2.41e-1)" "unprognostic (5.39e-2)" "unprognostic (7.98e-2)" "unprognostic (4.02e-1)" "unprognostic (1.25e-1)" "unprognostic (6.36e-2)" "unprognostic (2.20e-1)" "unprognostic (5.85e-2)" NAXE "AIBP, APOA1BP, MGC119143, MGC119144, MGC119145, YJEFN1" ENSG00000163382 "NAD(P)HX epimerase" Q8NCW5 1 156591756-156609507 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted secreted proteins" "Lipid transport, Transport" Isomerase "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 197.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA043766, HPA048164" Enhanced Approved Nucleoplasm,Vesicles,Cytosol "Secreted to blood" Transport NA NA 1200000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 97: Non-specific - Cellular respiration" 4 Nucleoplasm "Vesicles, Cytosol" "HPA043766: , HPA048164: " "unprognostic (4.67e-2)" "unprognostic (1.31e-1)" "unprognostic (3.72e-2)" "unprognostic (3.99e-3)" "unprognostic (3.31e-2)" "unprognostic (2.39e-2)" "unprognostic (1.53e-1)" "unprognostic (3.04e-3)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (4.37e-2)" "unprognostic (3.45e-2)" "unprognostic (1.68e-2)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (8.28e-2)" "unprognostic (7.73e-2)" "unprognostic (1.11e-1)" "unprognostic (6.75e-2)" "unprognostic (2.25e-2)" "unprognostic (5.78e-2)" "unprognostic (7.63e-2)" "unprognostic (1.02e-1)" "unprognostic (7.84e-3)" "unprognostic (8.41e-2)" "unprognostic (3.07e-1)" "unprognostic (1.41e-1)" "unprognostic (6.09e-2)" "unprognostic (6.30e-2)" "unprognostic (1.26e-1)" "unprognostic (2.96e-1)" NBN "AT-V1, AT-V2, ATV, NBS, NBS1" ENSG00000104320 Nibrin O60934 8 89924515-90003228 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Host-virus interaction, Meiosis" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 372.7;Cardiomyocytes: 1314.0;Neutrophils: 854.9" "Group enriched" "Detected in all" 5 "Adipocytes: 372.7;Myocytes: 1314.0;Neutrophils: 854.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 11980277.0" "Tissue enhanced" "Detected in many" "ovary: 3385466.7" "HPA001429, CAB003836, CAB080233" Supported Supported "Nucleoplasm,Mitotic chromosome,Golgi apparatus" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 79 Nucleoplasm "Mitotic chromosome, Golgi apparatus" "CAB003836: , CAB080233: , HPA001429: " "unprognostic (1.29e-3)" "unprognostic (1.13e-1)" "unprognostic (2.55e-1)" "unprognostic (3.41e-2)" "unprognostic (3.90e-2)" "unprognostic (1.44e-2)" "unprognostic (1.28e-1)" "unprognostic (3.13e-3)" "unprognostic (7.32e-2)" "unprognostic (6.29e-3)" "potential prognostic favorable (2.17e-4)" "unprognostic (1.85e-2)" "unprognostic (9.17e-2)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (1.51e-6)" "unprognostic (2.04e-2)" "unprognostic (8.16e-2)" "unprognostic (1.60e-1)" "unprognostic (6.57e-3)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (1.49e-2)" "unprognostic (7.70e-2)" "unprognostic (2.50e-2)" "unprognostic (4.73e-2)" "unprognostic (1.29e-2)" "unprognostic (1.48e-1)" "unprognostic (2.45e-1)" "unprognostic (7.81e-3)" "unprognostic (1.79e-1)" NBPF3 AE2 ENSG00000142794 "NBPF member 3" Q9H094 1 21440128-21485005 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 9.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 98.6;Early primary spermatocytes: 46.0;Leydig cells: 44.8" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 98.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Cell type enriched" "Detected in single" 2210 "Collecting ducts: 220962.2" "Not detected" "Not detected" "HPA042595, HPA043692, HPA044023, HPA046971, HPA058050, HPA073664" Approved Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 18: Adrenal cortex cells - Steroidogensis" "Nucleoplasm, Cytosol" "Nuclear speckles" "HPA042595: , HPA043692: , HPA044023: , HPA046971: , HPA058050: , HPA073664: " "potential prognostic favorable (9.12e-4)" "unprognostic (3.76e-2)" "unprognostic (1.88e-1)" "unprognostic (1.38e-2)" "unprognostic (1.75e-3)" "unprognostic (2.80e-1)" "unprognostic (7.35e-2)" "unprognostic (6.09e-2)" "unprognostic (9.45e-2)" "unprognostic (7.26e-3)" "unprognostic (7.88e-2)" "unprognostic (3.10e-1)" "unprognostic (7.19e-3)" "unprognostic (1.72e-1)" "unprognostic (2.23e-2)" "unprognostic (2.90e-1)" "unprognostic (1.88e-1)" "potential prognostic favorable (3.29e-4)" "unprognostic (2.05e-1)" "unprognostic (3.29e-1)" "unprognostic (3.07e-1)" "unprognostic (5.39e-3)" "unprognostic (5.39e-2)" "unprognostic (1.63e-1)" "unprognostic (3.03e-1)" NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 11.3;brain: 38.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1097.0;Adrenal medulla cells: 1106.2;Astrocytes: 1271.1;Bergmann glia: 2749.5;Brain excitatory neurons: 1376.0;Brain inhibitory neurons: 926.8;Ependymal cells: 975.9;Oligodendrocyte progenitor cells: 2609.3;Oligodendrocytes: 2578.9;Other brain neurons: 921.1;Schwann cells: 1302.0;Sertoli cells: 1315.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 1106.2;Ciliated cells: 975.9;Glial cells: 2749.5;Neuronal cells: 1376.0;Reproductive supporting cells: 1315.1" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Breast Invasive Carcinoma (TCGA): 6.5;Glioblastoma Multiforme (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "prostate cancer: 45.3;Rhabdoid: 16.5" "Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 129398139.6;Microglia and Neuropil: 163899448.8;Neurons: 47767882.5" "Tissue enriched" "Detected in many" "cerebral cortex: 221262343.6" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 30000000 "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Nuclear bodies, Plasma membrane" "HPA030900: , HPA030901: " "unprognostic (5.71e-2)" "unprognostic (3.28e-2)" "unprognostic (1.38e-1)" "unprognostic (1.41e-1)" "potential prognostic favorable (6.43e-4)" "unprognostic (1.27e-1)" "unprognostic (3.59e-2)" "unprognostic (6.73e-3)" "unprognostic (1.15e-1)" "unprognostic (7.35e-3)" "unprognostic (2.12e-1)" "unprognostic (1.11e-2)" "unprognostic (2.05e-2)" NCAPD2 "CAP-D2, CNAP1, hCAP-D2, KIAA0159" ENSG00000010292 "Non-SMC condensin I complex subunit D2" Q15021 12 6493356-6531955 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 71.5" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 108.4;Megakaryocyte progenitors: 77.7;Monocyte progenitors: 159.2;Neutrophil progenitors: 126.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 108.4;Mononuclear phagocytes: 159.2;Neutrophils: 126.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 2238578.8;Neutrophils: 2694394.0" "Tissue enriched" "Detected in some" "bone marrow: 5439879.8" "CAB012423, HPA036947, HPA037363" Approved Supported "Nucleoplasm,Nucleoli,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA Yes 22000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 37 "Nucleoplasm, Cytosol" "Nucleoli, Primary cilium, Centriolar satellite, Basal body" "CAB012423: , HPA036947: , HPA037363: " "unprognostic (2.51e-3)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" "unprognostic (4.47e-1)" "unprognostic (6.46e-2)" "unprognostic (1.45e-1)" "unprognostic (2.70e-1)" "unprognostic (1.37e-2)" "unprognostic (3.03e-1)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (4.02e-3)" "unprognostic (8.45e-3)" "unprognostic (1.55e-3)" "validated prognostic unfavorable (1.36e-7)" "validated prognostic unfavorable (2.81e-5)" "potential prognostic unfavorable (3.05e-4)" "unprognostic (1.23e-2)" "unprognostic (1.45e-2)" "unprognostic (2.88e-1)" "unprognostic (2.54e-2)" "unprognostic (6.99e-2)" "unprognostic (7.36e-3)" "unprognostic (3.01e-3)" "unprognostic (2.27e-1)" "unprognostic (2.94e-2)" "unprognostic (1.31e-2)" "unprognostic (1.51e-2)" "unprognostic (1.73e-2)" "unprognostic (1.98e-1)" "unprognostic (1.48e-1)" "unprognostic (2.11e-1)" NCAPG2 "CAP-G2, FLJ20311, hCAP-G2, LUZP5, MTB" ENSG00000146918 "Non-SMC condensin II complex subunit G2" Q86XI2 7 158631169-158704804 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 23.0;lymphoid tissue: 26.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 71.0;Endometrial luminal cells: 65.7;Erythrocyte progenitors: 156.6;Megakaryocyte progenitors: 98.9;Monocyte progenitors: 197.4;Neutrophil progenitors: 127.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 156.6;Mononuclear phagocytes: 197.4;Neutrophils: 127.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 2025901.0;Neutrophils: 971113.0" "Tissue enriched" "Detected in single" 13680 "bone marrow: 1368027.0" "HPA026631, HPA049637" Approved Supported "Nucleoplasm,Nuclear speckles" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 8 Nucleoplasm "Nuclear speckles" "HPA026631: , HPA049637: " "unprognostic (1.05e-1)" "unprognostic (3.64e-2)" "unprognostic (1.86e-2)" "unprognostic (2.32e-1)" "unprognostic (3.79e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (2.67e-2)" "unprognostic (2.06e-3)" "potential prognostic unfavorable (4.65e-7)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (1.37e-3)" "validated prognostic unfavorable (1.60e-5)" "validated prognostic unfavorable (6.71e-6)" "validated prognostic unfavorable (1.55e-4)" "validated prognostic unfavorable (6.53e-4)" "unprognostic (2.49e-1)" "unprognostic (3.29e-1)" "unprognostic (6.29e-2)" "unprognostic (2.30e-1)" "unprognostic (1.10e-3)" "unprognostic (2.46e-2)" "unprognostic (8.73e-2)" "unprognostic (2.61e-2)" "unprognostic (7.12e-2)" "unprognostic (1.25e-2)" "unprognostic (4.65e-2)" "unprognostic (2.52e-1)" "unprognostic (1.40e-2)" "unprognostic (7.25e-2)" NCAPH "BRRN1, CAP-H, hCAP-H" ENSG00000121152 "Non-SMC condensin I complex subunit H" Q15003 2 96335766-96377091 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 33.3;intestine: 8.7;lymphoid tissue: 34.8;testis: 33.1" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.0;Early primary spermatocytes: 71.5;Erythrocyte progenitors: 96.5;Late primary spermatocytes: 102.8;Megakaryocyte progenitors: 59.8;Monocyte progenitors: 89.9;Neutrophil progenitors: 42.4;Oocytes: 73.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 96.5;Megakaryocytes: 59.8;Mononuclear phagocytes: 89.9;Oocytes: 73.7;Spermatogenic cell types: 102.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 6.2" "Group enriched" "Detected in many" 5 "granulocytes: 3.7;T-cells: 6.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Pancreas - Macrophages, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" "Granulosa cells: 5074533.1;Neutrophils: 5758546.5" "Group enriched" "Detected in some" "bone marrow: 143492.4;lymphoid tissue: 53171.1" "HPA002647, HPA003008" Enhanced Supported Nucleoplasm,Vesicles,Cytosol Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 9: Non-specific - Receptor signaling" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 165 Cytosol "Nucleoplasm, Vesicles" "HPA002647: , HPA003008: " "unprognostic (2.89e-2)" "unprognostic (4.30e-2)" "unprognostic (1.05e-1)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (6.92e-2)" "unprognostic (2.43e-1)" "unprognostic (4.53e-3)" "unprognostic (8.65e-2)" "potential prognostic unfavorable (2.27e-5)" "potential prognostic unfavorable (4.32e-8)" "unprognostic (1.92e-3)" "potential prognostic unfavorable (3.98e-9)" "validated prognostic unfavorable (4.18e-6)" "validated prognostic unfavorable (3.91e-7)" "potential prognostic unfavorable (8.60e-5)" "unprognostic (1.13e-3)" "unprognostic (4.25e-2)" "unprognostic (8.59e-3)" "unprognostic (1.04e-1)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (3.67e-3)" "unprognostic (2.92e-1)" "unprognostic (1.72e-1)" "unprognostic (7.19e-2)" "unprognostic (1.73e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-1)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" NCAPH2 "384D8-2, CAP-H2, hCAP-H2" ENSG00000025770 "Non-SMC condensin II complex subunit H2" Q6IBW4 22 50508224-50524780 "Essential proteins, Predicted intracellular proteins" "DNA condensation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 67.2;Late spermatids: 189.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 189.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 3647 "Granulosa cells: 389339.4;Neurons: 426775.9;Neutrophils: 569129.9;Oocytes: 188644.1;T-cells: 249469.0" "Tissue enriched" "Detected in some" "bone marrow: 4159300.2" "HPA067932, HPA069056" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytokinetic bridge" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 15 Nucleoplasm "Cell Junctions, Cytokinetic bridge" "HPA067932: , HPA069056: " "unprognostic (1.93e-1)" "unprognostic (3.48e-1)" "unprognostic (8.66e-3)" "potential prognostic favorable (3.72e-4)" "unprognostic (2.95e-2)" "unprognostic (1.34e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-2)" "unprognostic (5.70e-3)" "unprognostic (9.13e-2)" "unprognostic (6.43e-2)" "unprognostic (1.95e-1)" "potential prognostic favorable (8.23e-4)" "validated prognostic unfavorable (3.67e-4)" "validated prognostic unfavorable (1.72e-4)" "unprognostic (1.21e-1)" "unprognostic (3.00e-2)" "unprognostic (1.33e-2)" "unprognostic (1.35e-1)" "unprognostic (5.54e-2)" "unprognostic (2.53e-2)" "unprognostic (3.42e-2)" "unprognostic (1.18e-2)" "unprognostic (8.08e-3)" "unprognostic (3.01e-1)" "unprognostic (8.02e-3)" "unprognostic (1.25e-1)" "unprognostic (5.58e-2)" "unprognostic (5.15e-2)" "unprognostic (2.44e-2)" "unprognostic (9.41e-2)" NCBP2 "Cbc2, CBP20, NIP1" ENSG00000114503 "Nuclear cap binding protein subunit 2" P52298 3 196935402-196942594 "Essential proteins, Predicted intracellular proteins, Transporters" "mRNA processing, mRNA splicing, mRNA transport, Nonsense-mediated mRNA decay, RNA-mediated gene silencing, Translation regulation, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 3716204.6" "Low tissue specificity" "Detected in many" "HPA044850, HPA062483" Supported Supported "Nucleoplasm,Basal body,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 33 Nucleoplasm "Basal body, Cytosol" "HPA044850: , HPA062483: " "unprognostic (2.51e-1)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (1.39e-1)" "unprognostic (9.06e-2)" "unprognostic (1.60e-2)" "unprognostic (1.44e-1)" "unprognostic (1.03e-1)" "unprognostic (5.25e-2)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (4.82e-2)" "unprognostic (8.94e-2)" "unprognostic (1.18e-3)" "validated prognostic unfavorable (1.28e-7)" "validated prognostic unfavorable (2.75e-4)" "unprognostic (1.11e-3)" "unprognostic (1.80e-3)" "unprognostic (4.62e-2)" "unprognostic (2.89e-2)" "unprognostic (3.55e-1)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (6.44e-5)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (4.06e-4)" "unprognostic (1.92e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.81e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-2)" "unprognostic (7.83e-2)" NCEH1 "AADACL1, KIAA1363, NCEH" ENSG00000144959 "Neutral cholesterol ester hydrolase 1" Q6PIU2 3 172630249-172711218 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 306.9;Endometrial glandular cells: 366.5;Pancreatic duct cells: 761.4;Urothelial cells: 570.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 570.9;Ductal cells: 761.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 201121507.9;Neurons: 92286376.3" "Tissue enhanced" "Detected in many" "cerebral cortex: 46412587.4;lymphoid tissue: 41894993.4" "HPA026888, HPA043873" Enhanced Approved "Endoplasmic reticulum" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 4 "Endoplasmic reticulum" "HPA026888: , HPA043873: " "unprognostic (8.66e-2)" "unprognostic (7.18e-2)" "unprognostic (5.31e-2)" "unprognostic (2.15e-2)" "unprognostic (9.16e-2)" "unprognostic (1.78e-1)" "unprognostic (2.67e-2)" "unprognostic (1.57e-3)" "unprognostic (2.24e-2)" "potential prognostic unfavorable (7.05e-4)" "potential prognostic favorable (7.38e-6)" "unprognostic (2.12e-1)" "unprognostic (3.96e-2)" "unprognostic (4.88e-2)" "unprognostic (3.48e-1)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (2.16e-2)" "unprognostic (1.36e-1)" "unprognostic (1.58e-1)" "unprognostic (9.40e-3)" "potential prognostic unfavorable (6.23e-4)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (2.32e-1)" "unprognostic (1.28e-1)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (6.94e-2)" "unprognostic (1.62e-1)" "unprognostic (5.17e-2)" "unprognostic (6.53e-3)" "unprognostic (2.84e-1)" NCKIPSD "AF3P21, DIP1, ORF1, SPIN90, WASLBP, WISH" ENSG00000213672 "NCK interacting protein with SH3 domain" Q9NZQ3 3 48673844-48686364 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 114.5" "Cell type enhanced" "Detected in many" "Megakaryocytes: 68.0;Oocytes: 69.1;Peritubular myoid cells: 45.9;Platelets: 70.5" "Cell type enhanced" "Detected in all" "Megakaryocytes: 68.0;Oocytes: 69.1;Platelets: 70.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 16109623.9;Microglia and Neuropil: 17447924.0" "Group enriched" "Detected in many" "bone marrow: 6202815.4;cerebral cortex: 18784824.3" HPA064985 Supported "Nucleoplasm,Plasma membrane" NA NA 33000 "Cluster 13: Non-specific - Mitochondria" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 47: Platelets - Hemostasis" 36 Nucleoplasm "Plasma membrane" "HPA064985: " "unprognostic (9.70e-2)" "unprognostic (1.09e-1)" "unprognostic (2.15e-1)" "unprognostic (1.30e-1)" "unprognostic (1.69e-1)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" "unprognostic (2.93e-1)" "unprognostic (2.43e-1)" "unprognostic (4.30e-3)" "validated prognostic favorable (8.93e-5)" "validated prognostic favorable (4.23e-4)" "potential prognostic favorable (2.28e-5)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (1.27e-1)" "unprognostic (4.55e-3)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (5.88e-2)" "unprognostic (6.51e-3)" "unprognostic (2.07e-1)" "unprognostic (2.68e-1)" "unprognostic (5.68e-2)" "unprognostic (2.09e-2)" "unprognostic (1.78e-1)" "unprognostic (1.66e-1)" "unprognostic (2.44e-1)" "unprognostic (1.65e-1)" "unprognostic (8.40e-2)" "unprognostic (4.30e-1)" "unprognostic (2.20e-1)" "unprognostic (1.22e-1)" NCL "C23, Nsr1" ENSG00000115053 Nucleolin P19338 2 231453531-231483641 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 1065.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004210, HPA023981, HPA071110" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 1900000 "Cluster 30: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 300 "Nucleoplasm, Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB004210: , HPA023981: , HPA071110: " "unprognostic (6.96e-2)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (4.25e-3)" "unprognostic (1.00e-1)" "unprognostic (3.56e-1)" "unprognostic (2.33e-2)" "unprognostic (2.85e-2)" "unprognostic (1.57e-2)" "unprognostic (5.20e-2)" "potential prognostic favorable (6.60e-5)" "unprognostic (4.51e-2)" "unprognostic (5.17e-2)" "validated prognostic unfavorable (2.59e-7)" "validated prognostic unfavorable (3.33e-7)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (1.83e-3)" "unprognostic (4.79e-2)" "unprognostic (1.83e-2)" "unprognostic (1.89e-1)" "unprognostic (2.77e-1)" "unprognostic (1.40e-2)" "unprognostic (1.33e-2)" "unprognostic (7.44e-2)" "unprognostic (5.52e-2)" "unprognostic (2.77e-2)" "unprognostic (3.87e-2)" "unprognostic (4.95e-2)" "unprognostic (3.49e-1)" "unprognostic (1.41e-1)" "unprognostic (2.25e-2)" NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491254-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Bergmann glia: 1220.4;Neutrophils: 2074.9" "Cell type enhanced" "Detected in all" "Neutrophils: 2074.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Distal tubules: 11614103.1;Proximal tubules: 12870528.3" "Group enriched" "Detected in some" "bone marrow: 831425.9;intestine: 2358373.2;ovary: 1357149.3" "CAB019402, HPA070213, HPA070520" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" 84 "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane" "CAB019402: , HPA070213: , HPA070520: " "unprognostic (1.90e-1)" "unprognostic (2.11e-1)" "unprognostic (5.11e-2)" "unprognostic (3.61e-2)" "unprognostic (1.98e-2)" "unprognostic (3.14e-2)" "unprognostic (8.90e-2)" "unprognostic (9.48e-2)" "unprognostic (2.00e-2)" "unprognostic (5.22e-3)" "potential prognostic favorable (1.39e-6)" "unprognostic (5.70e-3)" "unprognostic (2.35e-1)" "unprognostic (1.73e-2)" "unprognostic (2.01e-1)" "unprognostic (1.20e-1)" "unprognostic (2.79e-1)" "unprognostic (1.58e-1)" "unprognostic (1.73e-1)" "unprognostic (1.69e-1)" "unprognostic (2.88e-1)" "unprognostic (3.34e-2)" "unprognostic (8.23e-2)" "unprognostic (1.97e-1)" "unprognostic (9.24e-2)" "unprognostic (6.04e-2)" "unprognostic (1.15e-1)" "unprognostic (2.63e-2)" "unprognostic (2.90e-1)" "unprognostic (3.12e-2)" "unprognostic (1.52e-2)" NCOA7 "dJ187J11.3, ERAP140, TLDC4" ENSG00000111912 "Nuclear receptor coactivator 7" Q8NI08 6 125781161-125932034 "Predicted intracellular proteins, Transporters" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 1214.6;Salivary ionocytes: 924.6" "Cell type enhanced" "Detected in all" "Basal cells: 1214.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 7860422.2;Microglia and Neuropil: 10136468.1;Neurons: 4758553.4;Oocytes: 2545718.7" "Tissue enhanced" "Detected in many" "cerebral cortex: 26766966.2" "HPA030289, HPA030290, HPA030291, HPA030292" Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 41: Basophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 8 "Nucleoplasm, Nuclear bodies" "Golgi apparatus" "HPA030289: , HPA030290: , HPA030291: , HPA030292: " "unprognostic (6.56e-2)" "unprognostic (7.62e-2)" "unprognostic (1.72e-1)" "unprognostic (5.34e-3)" "unprognostic (1.03e-2)" "unprognostic (1.30e-1)" "unprognostic (9.99e-2)" "unprognostic (1.70e-2)" "unprognostic (3.38e-2)" "unprognostic (1.69e-1)" "validated prognostic favorable (4.72e-7)" "validated prognostic favorable (8.44e-4)" "unprognostic (1.80e-2)" "unprognostic (1.24e-1)" "unprognostic (3.98e-2)" "unprognostic (6.63e-2)" "unprognostic (1.81e-1)" "unprognostic (2.24e-2)" "unprognostic (1.66e-1)" "unprognostic (1.54e-2)" "unprognostic (4.08e-3)" "unprognostic (4.31e-2)" "unprognostic (1.46e-1)" "unprognostic (1.35e-1)" "unprognostic (3.01e-2)" "potential prognostic favorable (9.40e-5)" "unprognostic (2.40e-1)" "unprognostic (3.61e-1)" "unprognostic (4.68e-2)" "unprognostic (1.25e-1)" "unprognostic (1.02e-1)" NDC80 "HEC, HEC1, hsNDC80, KNTC2, TID3" ENSG00000080986 "NDC80 kinetochore complex component" O14777 18 2571557-2616635 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.4;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 71.9;Enteric transient amplifying cells: 29.6;Erythrocyte progenitors: 80.5;Extravillous trophoblasts: 31.1;Late primary spermatocytes: 73.0;Megakaryocyte progenitors: 62.0;Monocyte progenitors: 101.4;Neutrophil progenitors: 50.2;Oocytes: 82.9" "Cell type enhanced" "Detected in many" "Erythrocytes: 80.5;Megakaryocytes: 62.0;Mononuclear phagocytes: 101.4;Oocytes: 82.9;Spermatogenic cell types: 73.0" "Group enriched" "Detected in some" 5 "fibroblast: 7.8;leukocyte: 8.8;pericyte: 3.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 7.1;granulocytes: 8.4;T-cells: 11.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Fibroblasts, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 5713 "Granulosa cells: 813183.9;Neutrophils: 343738.1;Oocytes: 556853.1" "Tissue enriched" "Detected in single" 822 "bone marrow: 82186.9" HPA066330 Supported "Nucleoplasm,Nuclear speckles,Centrosome,Cytosol" NA Yes "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 37: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 114 "Nucleoplasm, Nuclear speckles" "Centrosome, Cytosol" "HPA066330: " "unprognostic (1.23e-1)" "unprognostic (2.26e-1)" "unprognostic (3.72e-1)" "unprognostic (7.83e-2)" "unprognostic (2.84e-1)" "unprognostic (2.00e-2)" "unprognostic (1.79e-1)" "unprognostic (1.56e-2)" "unprognostic (4.33e-2)" "unprognostic (2.33e-3)" "potential prognostic unfavorable (2.06e-9)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (4.98e-4)" "validated prognostic unfavorable (4.20e-7)" "validated prognostic unfavorable (2.19e-8)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (4.54e-2)" "unprognostic (1.35e-2)" "unprognostic (8.94e-2)" "unprognostic (3.93e-2)" "unprognostic (2.92e-1)" "unprognostic (4.03e-3)" "unprognostic (4.61e-2)" "unprognostic (2.42e-2)" "unprognostic (3.47e-1)" "unprognostic (2.64e-1)" "unprognostic (3.38e-3)" "unprognostic (8.57e-3)" "unprognostic (2.14e-1)" "unprognostic (6.79e-2)" "unprognostic (1.24e-1)" NDFIP2 "KIAA1165, N4wbp5a" ENSG00000102471 "Nedd4 family interacting protein 2" Q9NV92 13 79481155-79556077 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 404.4;Esophageal apical cells: 719.9;Late spermatids: 495.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 719.9;Spermatogenic cell types: 495.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 28.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 28.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2672 "cerebral cortex: 267211.7" HPA009160 Uncertain Supported Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 76: Non-specific - Metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 10 Vesicles "HPA009160: " "unprognostic (1.87e-1)" "unprognostic (6.80e-2)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (1.09e-1)" "unprognostic (3.79e-2)" "unprognostic (8.36e-2)" "unprognostic (8.74e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (9.83e-4)" "unprognostic (4.34e-2)" "potential prognostic favorable (1.73e-11)" "unprognostic (8.89e-2)" "unprognostic (3.80e-1)" "unprognostic (2.70e-1)" "unprognostic (6.57e-2)" "unprognostic (1.30e-3)" "unprognostic (3.48e-3)" "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (1.84e-1)" "unprognostic (1.40e-2)" "unprognostic (3.60e-3)" "unprognostic (3.74e-2)" "unprognostic (2.23e-2)" "unprognostic (1.17e-2)" "unprognostic (1.74e-1)" "unprognostic (1.06e-1)" "unprognostic (6.38e-2)" "unprognostic (1.58e-1)" "unprognostic (1.33e-1)" "unprognostic (2.68e-2)" NDP "EVR2, norrin" ENSG00000124479 "Norrin cystine knot growth factor NDP" Q00604 X 43948776-43973395 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Sensory transduction, Vision, Wnt signaling pathway" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.4;ovary: 31.8" "Cell type enhanced" "Detected in some" "Astrocytes: 34.9;Bergmann glia: 13.0;Decidual stromal cells: 52.9;Endometrial luminal cells: 40.5;Epididymal principal cells: 15.3;Granulosa cells: 89.2;Müller glia: 88.7;Oligodendrocytes: 13.1;Ovarian stromal cells: 49.1" "Group enriched" "Detected in some" 8 "Glial cells: 88.7;Luminal cells: 40.5;Reproductive supporting cells: 89.2;Stromal cells: 52.9" "Cell type enhanced" "Detected in many" "astrocyte: 36.7;Bergmann glia: 19.8" "Cancer enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 46.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Brain cancer: 9.5" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 99691.5;Oocytes: 226255.2" "Tissue enriched" "Detected in some" "ovary: 176435.9" HPA003095 Supported Nucleoplasm,Nucleoli,Vesicles "Secreted to extracellular matrix" Other NA NA "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 94: Gonadal somatic cells - Mixed function" 13 Vesicles "Nucleoplasm, Nucleoli" "HPA003095: " "unprognostic (4.09e-2)" "unprognostic (4.92e-2)" "unprognostic (9.24e-3)" "unprognostic (2.77e-1)" "unprognostic (1.09e-1)" "unprognostic (1.37e-1)" "unprognostic (1.32e-1)" "unprognostic (2.46e-1)" "unprognostic (2.99e-1)" "unprognostic (2.58e-1)" "unprognostic (8.67e-2)" "unprognostic (2.63e-1)" "unprognostic (9.57e-3)" NDRG4 "KIAA1180, SMAP-8" ENSG00000103034 "NDRG family member 4" Q9ULP0 16 58462846-58513628 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 347.4;heart muscle: 326.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 149.0;Adrenal medulla cells: 265.9;Bergmann glia: 254.6;Brain excitatory neurons: 141.6;Brain inhibitory neurons: 143.1;Cardiomyocytes: 264.1;Corticotrophs: 153.5;Epididymal basal cells: 115.7;Other brain neurons: 109.8;Retinal amacrine cells: 105.7;Retinal ganglion cells: 181.6;Retinal horizontal cells: 454.8;Sertoli cells: 196.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 265.9;Glial cells: 254.6;Myocytes: 264.1;Neuronal cells: 454.8;Reproductive supporting cells: 196.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 84.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Neuroblastoma: 65.0;Rhabdoid: 37.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 30644226.6;Cardiomyocytes: 10011597.6;Microglia and Neuropil: 33150689.3;Neurons: 12648765.8" "Group enriched" "Detected in many" "cerebral cortex: 44242933.8;heart muscle: 15399668.7" "HPA015313, HPA015779" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 9 Cytosol "Plasma membrane" "HPA015313: , HPA015779: " "unprognostic (1.86e-1)" "unprognostic (1.34e-1)" "unprognostic (2.08e-1)" "unprognostic (4.04e-1)" "unprognostic (1.49e-1)" "unprognostic (1.19e-1)" "unprognostic (4.22e-1)" "unprognostic (7.78e-2)" "unprognostic (2.35e-1)" "unprognostic (9.94e-2)" "unprognostic (1.81e-1)" "unprognostic (9.48e-2)" "unprognostic (5.98e-2)" "unprognostic (5.11e-2)" "unprognostic (1.10e-1)" "unprognostic (1.82e-2)" "unprognostic (6.67e-2)" "unprognostic (1.34e-1)" "unprognostic (7.76e-2)" "unprognostic (2.51e-1)" "unprognostic (4.97e-1)" "unprognostic (1.36e-2)" "unprognostic (3.02e-3)" "unprognostic (9.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (8.29e-2)" "unprognostic (5.59e-3)" "unprognostic (1.75e-1)" "unprognostic (5.02e-3)" "unprognostic (3.95e-2)" NDST2 "HSST2, NST2" ENSG00000166507 "N-deacetylase and N-sulfotransferase 2" P52849 10 73801911-73811798 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Multifunctional enzyme, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Epididymal principal cells: 2.9;Late primary spermatocytes: 2.4;Late spermatids: 5.1;Mast cells: 9.0;Microglia: 3.0;Paneth cells: 3.9" "Cell type enhanced" "Detected in some" "Mast cells: 9.0;Spermatogenic cell types: 5.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 369646.1;Neutrophils: 507037.0" "Tissue enriched" "Detected in single" 999 "lymphoid tissue: 99944.7" HPA051515 Approved Approved Cytosol NA NA 130000 "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 15: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" Cytosol "HPA051515: " "unprognostic (8.77e-2)" "unprognostic (1.16e-1)" "unprognostic (9.71e-2)" "unprognostic (1.60e-2)" "unprognostic (1.55e-2)" "unprognostic (1.22e-1)" "unprognostic (2.68e-2)" "potential prognostic favorable (6.41e-5)" "unprognostic (6.93e-2)" "unprognostic (8.85e-2)" "unprognostic (6.51e-2)" "unprognostic (2.01e-2)" "unprognostic (1.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.33e-1)" "unprognostic (8.85e-3)" "unprognostic (7.43e-2)" "unprognostic (4.25e-2)" "unprognostic (1.40e-1)" "unprognostic (1.28e-2)" "unprognostic (1.10e-1)" "unprognostic (8.75e-3)" "unprognostic (5.39e-2)" "unprognostic (1.06e-1)" "unprognostic (4.81e-2)" "unprognostic (3.65e-1)" "unprognostic (1.77e-1)" "unprognostic (1.96e-1)" "unprognostic (3.01e-1)" "unprognostic (8.58e-2)" "unprognostic (1.02e-1)" NDUFA1 "CI-MWFE, MWFE" ENSG00000125356 "NADH:ubiquinone oxidoreductase subunit A1" O15239 X 119871832-119876662 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 1658.3" "Cell type enhanced" "Detected in many" "Colonocytes: 1316.4;Enterocytes: 1380.3;Hepatocytes: 1151.9;Parietal cells: 2681.9" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 2681.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 10480631.9;Proximal tubules: 9321105.1" "Tissue enhanced" "Detected in many" "heart muscle: 36285795.1" "HPA029768, HPA054359" Enhanced Supported Mitochondria,Cytosol No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 35 "Mitochondria, Cytosol" "HPA029768: , HPA054359: " "unprognostic (1.98e-1)" "unprognostic (1.38e-2)" "unprognostic (3.92e-2)" "potential prognostic favorable (1.84e-4)" "unprognostic (3.09e-1)" "unprognostic (2.16e-3)" "unprognostic (5.89e-2)" "unprognostic (1.69e-1)" "unprognostic (1.54e-3)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (1.17e-2)" "unprognostic (2.08e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-1)" "unprognostic (1.66e-2)" "unprognostic (7.22e-2)" "unprognostic (3.06e-1)" "unprognostic (9.28e-3)" "unprognostic (8.41e-2)" "unprognostic (1.52e-1)" "unprognostic (2.08e-1)" "unprognostic (1.87e-2)" "unprognostic (2.77e-2)" "unprognostic (8.66e-2)" "unprognostic (2.83e-2)" "unprognostic (1.73e-2)" "unprognostic (3.85e-2)" "unprognostic (1.89e-1)" "unprognostic (3.12e-2)" "unprognostic (5.09e-2)" "unprognostic (1.23e-1)" NDUFA11 B14.7 ENSG00000174886 "NADH:ubiquinone oxidoreductase subunit A11" Q86Y39 19 5891276-5904006 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 833.1;Hepatocytes: 621.8;Late spermatids: 602.8;Parietal cells: 712.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 20728816.3;Distal tubules: 18519208.7" "Tissue enhanced" "Detected in many" "heart muscle: 3459717.5" HPA072209 Approved "Mitochondria,Perinuclear theca,Principal piece,End piece" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 5 "Mitochondria, End piece" "Perinuclear theca, Principal piece" "HPA072209: " "unprognostic (2.23e-1)" "unprognostic (2.66e-1)" "unprognostic (1.89e-2)" "potential prognostic favorable (5.46e-4)" "unprognostic (2.40e-1)" "unprognostic (2.43e-2)" "unprognostic (9.80e-2)" "unprognostic (2.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.08e-2)" "unprognostic (6.94e-3)" "unprognostic (4.60e-3)" "unprognostic (7.94e-3)" "unprognostic (1.08e-1)" "unprognostic (2.78e-2)" "unprognostic (1.79e-1)" "unprognostic (4.15e-2)" "unprognostic (8.59e-2)" "unprognostic (3.21e-1)" "unprognostic (6.17e-2)" "unprognostic (2.42e-1)" "unprognostic (3.80e-3)" "unprognostic (2.61e-1)" "unprognostic (3.07e-1)" "unprognostic (2.89e-1)" "unprognostic (8.18e-2)" "unprognostic (2.08e-1)" "unprognostic (8.40e-2)" "potential prognostic favorable (6.92e-4)" "unprognostic (5.17e-3)" "unprognostic (1.27e-2)" NDUFA12 "B17.2, DAP13" ENSG00000184752 "NADH:ubiquinone oxidoreductase subunit A12" Q9UI09 12 94895297-95003748 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 522.0;tongue: 528.2" "Cell type enhanced" "Detected in many" "Parietal cells: 466.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 170933404.8" "Tissue enhanced" "Detected in all" "heart muscle: 173234264.8" HPA039903 Supported Supported Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 55 Mitochondria Cytosol "HPA039903: " "unprognostic (1.02e-1)" "unprognostic (1.52e-2)" "unprognostic (2.27e-2)" "unprognostic (8.73e-3)" "unprognostic (6.47e-3)" "unprognostic (3.40e-2)" "unprognostic (2.67e-1)" "unprognostic (8.67e-2)" "potential prognostic unfavorable (9.08e-4)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (4.36e-2)" "unprognostic (2.62e-1)" "unprognostic (1.80e-2)" "unprognostic (2.00e-3)" "potential prognostic unfavorable (2.17e-5)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (4.96e-2)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (5.25e-2)" "unprognostic (1.43e-2)" "unprognostic (7.66e-2)" "unprognostic (5.44e-3)" "unprognostic (3.42e-2)" "unprognostic (2.45e-2)" "unprognostic (2.30e-1)" "unprognostic (2.08e-1)" "unprognostic (7.84e-2)" "unprognostic (1.33e-1)" "unprognostic (1.65e-1)" "unprognostic (2.56e-1)" NDUFA8 "MGC793, PGIV" ENSG00000119421 "NADH:ubiquinone oxidoreductase subunit A8" P51970 9 122144058-122159779 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.0" "Cell type enhanced" "Detected in many" "Early spermatids: 374.1;Late primary spermatocytes: 791.3;Oocytes: 400.6;Parietal cells: 355.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 791.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 278395451.0;Cardiomyocytes: 395193571.6" "Tissue enriched" "Detected in all" "heart muscle: 1309303153.0" "HPA041510, HPA041600" Enhanced Supported "Mitochondria,Mid piece,Principal piece,End piece" NA NA 9300 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 28 Mitochondria "Mid piece, Principal piece, End piece" "HPA041510: , HPA041600: " "unprognostic (2.58e-3)" "unprognostic (1.76e-1)" "unprognostic (9.62e-2)" "unprognostic (2.37e-3)" "unprognostic (3.69e-1)" "unprognostic (1.19e-2)" "unprognostic (5.09e-1)" "unprognostic (1.56e-1)" "unprognostic (7.54e-3)" "unprognostic (1.37e-1)" "potential prognostic favorable (7.44e-5)" "unprognostic (6.46e-2)" "unprognostic (2.10e-2)" "unprognostic (1.80e-3)" "potential prognostic unfavorable (1.94e-4)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (3.41e-1)" "unprognostic (1.75e-1)" "unprognostic (1.66e-1)" "unprognostic (1.95e-1)" "unprognostic (3.83e-1)" "unprognostic (3.05e-2)" "unprognostic (3.01e-3)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.72e-1)" "unprognostic (1.49e-1)" "unprognostic (1.46e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-1)" "unprognostic (5.36e-2)" NDUFA9 "CI-39k, COQ11, NDUFS2L, SDR22E1" ENSG00000139180 "NADH:ubiquinone oxidoreductase subunit A9" Q16795 12 4649095-4694317 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 786.5" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 786.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 803174362.0" "Tissue enhanced" "Detected in all" "heart muscle: 149353825.9" "HPA042268, HPA073212" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 37: Neurons - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 114 Mitochondria Nucleoplasm "HPA042268: , HPA073212: " "unprognostic (1.02e-1)" "unprognostic (1.24e-1)" "unprognostic (5.97e-2)" "unprognostic (5.16e-3)" "unprognostic (1.57e-1)" "unprognostic (1.35e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (2.06e-4)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (8.88e-2)" "unprognostic (6.13e-2)" "potential prognostic favorable (1.94e-4)" "unprognostic (7.42e-3)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (5.05e-3)" "unprognostic (7.69e-2)" "unprognostic (1.45e-2)" "unprognostic (1.62e-1)" "unprognostic (4.45e-1)" "unprognostic (1.27e-1)" "unprognostic (1.08e-1)" "unprognostic (1.79e-3)" "unprognostic (3.15e-1)" "unprognostic (1.59e-2)" "unprognostic (9.44e-2)" "unprognostic (1.65e-1)" "unprognostic (3.55e-1)" "unprognostic (1.86e-1)" "unprognostic (2.70e-1)" "unprognostic (1.71e-1)" NDUFAB1 "ACP, ACP1, FASN2A, SDAP" ENSG00000004779 "NADH:ubiquinone oxidoreductase subunit AB1" O14561 16 23581014-23596316 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 612.8" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 492.7;Esophageal suprabasal cells: 491.9;Parietal cells: 666.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14905826.2" "Tissue enriched" "Detected in all" "heart muscle: 247621006.2" "HPA054364, HPA076020" Approved Supported Mitochondria No No 26000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 60 Mitochondria "HPA054364: , HPA076020: " "unprognostic (6.81e-2)" "potential prognostic unfavorable (8.25e-5)" "unprognostic (1.68e-2)" "unprognostic (6.83e-3)" "unprognostic (1.11e-1)" "unprognostic (2.41e-2)" "unprognostic (2.53e-1)" "unprognostic (1.46e-1)" "unprognostic (1.41e-2)" "unprognostic (1.94e-1)" "unprognostic (1.50e-3)" "unprognostic (1.85e-1)" "unprognostic (6.77e-3)" "unprognostic (2.24e-2)" "unprognostic (9.91e-3)" "unprognostic (8.49e-3)" "unprognostic (5.14e-3)" "unprognostic (9.14e-2)" "unprognostic (2.83e-2)" "unprognostic (1.79e-1)" "unprognostic (9.32e-2)" "unprognostic (8.38e-2)" "unprognostic (8.97e-2)" "unprognostic (9.22e-2)" "unprognostic (2.91e-2)" "unprognostic (3.27e-1)" "unprognostic (2.13e-1)" "unprognostic (4.74e-2)" "unprognostic (2.12e-1)" "unprognostic (1.95e-1)" "unprognostic (4.09e-2)" NDUFB11 "ESSS, Np15, NP17.3" ENSG00000147123 "NADH:ubiquinone oxidoreductase subunit B11" Q9NX14 X 47142071-47145466 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Cardiomyopathy, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 661.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1352.4;Hepatocytes: 762.1;Parietal cells: 972.3" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1352.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 129006250.5" "Tissue enriched" "Detected in all" "heart muscle: 188686782.5" HPA030367 Supported Supported "Mitochondria,Acrosome,Equatorial segment,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 40 Mitochondria "Acrosome, Equatorial segment, Connecting piece, Mid piece, Principal piece" "HPA030367: " "unprognostic (1.27e-1)" "unprognostic (2.96e-2)" "unprognostic (1.97e-1)" "unprognostic (6.33e-3)" "unprognostic (1.83e-1)" "unprognostic (3.14e-2)" "unprognostic (4.14e-1)" "unprognostic (1.18e-2)" "unprognostic (1.21e-1)" "unprognostic (4.69e-2)" "unprognostic (1.37e-2)" "unprognostic (1.16e-2)" "unprognostic (2.43e-2)" "unprognostic (4.16e-3)" "potential prognostic unfavorable (4.69e-4)" "unprognostic (5.67e-2)" "unprognostic (2.15e-1)" "unprognostic (6.42e-2)" "unprognostic (1.82e-1)" "unprognostic (1.42e-2)" "unprognostic (5.29e-2)" "unprognostic (8.82e-3)" "unprognostic (1.93e-1)" "unprognostic (2.67e-1)" "unprognostic (2.90e-1)" "unprognostic (2.44e-1)" "unprognostic (3.37e-1)" "unprognostic (7.67e-2)" "unprognostic (1.70e-1)" "unprognostic (1.34e-1)" "unprognostic (3.27e-2)" NDUFB2 "AGGG, CI-AGGG" ENSG00000090266 "NADH:ubiquinone oxidoreductase subunit B2" O95178 7 140690777-140722790 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1116.6;Hepatocytes: 1216.3;Parietal cells: 1419.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 84737087.7" "Group enriched" "Detected in many" "heart muscle: 154917835.1;skeletal muscle: 43960258.0" HPA051377 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 1 Nucleoplasm Mitochondria "HPA051377: " "unprognostic (1.85e-1)" "unprognostic (3.69e-1)" "unprognostic (2.38e-1)" "unprognostic (5.55e-2)" "unprognostic (2.46e-2)" "unprognostic (3.75e-3)" "potential prognostic unfavorable (3.65e-6)" "unprognostic (4.26e-2)" "unprognostic (1.39e-1)" "unprognostic (1.20e-3)" "unprognostic (2.67e-3)" "unprognostic (1.47e-2)" "potential prognostic favorable (1.86e-4)" "unprognostic (3.78e-3)" "potential prognostic unfavorable (5.94e-4)" "unprognostic (4.48e-2)" "unprognostic (9.30e-2)" "unprognostic (3.09e-2)" "unprognostic (4.33e-2)" "unprognostic (4.09e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (1.91e-4)" "unprognostic (3.48e-2)" "unprognostic (9.66e-2)" "unprognostic (1.05e-1)" "unprognostic (1.36e-1)" "unprognostic (1.97e-1)" "unprognostic (1.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.79e-2)" "unprognostic (1.03e-1)" NDUFB4 B15 ENSG00000065518 "NADH:ubiquinone oxidoreductase subunit B4" O95168 3 120596328-120602507 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 887.5" "Cell type enhanced" "Detected in many" "Early spermatids: 955.0;Esophageal apical cells: 940.3;Late primary spermatocytes: 1280.0;Parietal cells: 1127.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1280.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Capillaries: 214129867.4;Cardiomyocytes: 322285327.5" "Group enriched" "Detected in all" "cerebral cortex: 40035281.1;heart muscle: 90757949.2;skeletal muscle: 24096287.7" "HPA051739, HPA064441" Enhanced Approved "Nucleoplasm,Nuclear membrane,Mitochondria,Principal piece" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "Nucleoplasm, Nuclear membrane, Principal piece" "HPA051739: , HPA064441: " "unprognostic (2.12e-1)" "unprognostic (4.60e-2)" "unprognostic (2.52e-2)" "potential prognostic favorable (4.81e-4)" "unprognostic (5.10e-3)" "unprognostic (5.94e-2)" "unprognostic (1.89e-1)" "unprognostic (9.76e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-2)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "unprognostic (2.29e-1)" "unprognostic (1.91e-3)" "unprognostic (4.80e-3)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (5.63e-2)" "unprognostic (3.04e-1)" "unprognostic (2.96e-1)" "potential prognostic favorable (9.06e-4)" "unprognostic (5.59e-2)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (1.89e-1)" "unprognostic (2.88e-1)" "unprognostic (3.42e-1)" "unprognostic (9.58e-3)" "unprognostic (2.96e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-1)" "unprognostic (7.68e-2)" "unprognostic (3.85e-2)" NDUFB6 "B17, CI" ENSG00000165264 "NADH:ubiquinone oxidoreductase subunit B6" O95139 9 32553001-32573184 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 1080.7;Late primary spermatocytes: 689.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1080.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 25162327.8" "Group enriched" "Detected in many" "cerebral cortex: 19288308.4;heart muscle: 42859642.6;skeletal muscle: 18002952.9" "HPA044001, HPA053334" Supported Approved Nucleoplasm,Mitochondria No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 28 Mitochondria Nucleoplasm "HPA044001: , HPA053334: " "unprognostic (1.39e-1)" "unprognostic (2.78e-1)" "unprognostic (1.99e-3)" "unprognostic (4.64e-2)" "unprognostic (1.29e-1)" "unprognostic (1.16e-1)" "unprognostic (5.74e-1)" "unprognostic (2.08e-1)" "unprognostic (4.42e-2)" "unprognostic (1.37e-2)" "potential prognostic favorable (1.20e-11)" "unprognostic (9.10e-2)" "potential prognostic favorable (8.83e-5)" "unprognostic (9.13e-2)" "unprognostic (2.49e-2)" "unprognostic (2.95e-2)" "unprognostic (3.90e-2)" "unprognostic (6.28e-2)" "unprognostic (1.01e-1)" "unprognostic (2.84e-3)" "unprognostic (8.61e-2)" "unprognostic (2.06e-1)" "unprognostic (8.33e-2)" "unprognostic (8.02e-2)" "unprognostic (5.05e-2)" "unprognostic (1.61e-1)" "unprognostic (5.99e-3)" "unprognostic (3.91e-1)" "unprognostic (1.64e-1)" "unprognostic (2.23e-1)" "unprognostic (2.33e-1)" NDUFB9 "B22, LYRM3, UQOR22" ENSG00000147684 "NADH:ubiquinone oxidoreductase subunit B9" Q9Y6M9 8 124539101-124580648 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1286.6;tongue: 1386.4" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 813.4;Esophageal suprabasal cells: 779.5;Gastric progenitor cells: 1027.9;Late spermatids: 1280.7;Parietal cells: 1002.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1280.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 279928303.7" "Tissue enhanced" "Detected in all" "heart muscle: 185003604.5" HPA042768 Approved Supported Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 55 Mitochondria "HPA042768: " "unprognostic (2.20e-1)" "unprognostic (4.21e-3)" "unprognostic (2.29e-1)" "unprognostic (8.08e-2)" "unprognostic (3.24e-1)" "unprognostic (4.56e-3)" "unprognostic (3.80e-1)" "unprognostic (1.56e-3)" "unprognostic (2.03e-2)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.79e-1)" "unprognostic (1.54e-2)" "unprognostic (1.23e-1)" "unprognostic (3.19e-3)" "unprognostic (3.90e-2)" "unprognostic (4.26e-2)" "unprognostic (2.68e-1)" "unprognostic (7.03e-2)" "unprognostic (2.58e-1)" "unprognostic (1.63e-1)" "unprognostic (2.19e-2)" "unprognostic (6.86e-2)" "unprognostic (2.85e-1)" "unprognostic (2.31e-1)" "unprognostic (1.05e-1)" "unprognostic (2.34e-1)" "unprognostic (2.22e-1)" "unprognostic (1.17e-1)" "unprognostic (1.33e-1)" "unprognostic (2.16e-1)" NDUFC1 KFYI ENSG00000109390 "NADH:ubiquinone oxidoreductase subunit C1" O43677 4 139266880-139302551 "Metabolic proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "heart muscle: 78.4;skeletal muscle: 251.3;tongue: 148.5" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 966.0;Parietal cells: 857.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2236694.9;Skeletal myofibers: 2507214.6" "Tissue enriched" "Detected in single" 7961 "heart muscle: 796067.9" "HPA044556, HPA062427" Enhanced Supported Mitochondria No No "Cluster 46: Basophils - Proteolysis" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" Mitochondria "HPA044556: , HPA062427: " "unprognostic (4.07e-2)" "unprognostic (1.39e-2)" "unprognostic (4.81e-3)" "unprognostic (3.14e-2)" "unprognostic (8.18e-3)" "unprognostic (3.03e-1)" "unprognostic (5.58e-3)" "unprognostic (7.52e-2)" "unprognostic (9.97e-2)" "unprognostic (5.06e-3)" "potential prognostic favorable (3.17e-4)" "unprognostic (5.65e-3)" "potential prognostic favorable (9.51e-5)" "unprognostic (1.08e-2)" "unprognostic (1.57e-1)" "unprognostic (9.62e-2)" "unprognostic (6.70e-2)" "unprognostic (2.28e-1)" "unprognostic (1.48e-2)" "unprognostic (3.36e-1)" "unprognostic (4.05e-1)" "unprognostic (1.30e-3)" "unprognostic (1.41e-1)" "unprognostic (7.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.29e-1)" "unprognostic (4.48e-2)" "unprognostic (2.07e-1)" "unprognostic (1.91e-1)" "unprognostic (4.75e-2)" "unprognostic (1.26e-1)" NDUFS2 CI-49 ENSG00000158864 "NADH:ubiquinone oxidoreductase core subunit S2" O75306 1 161197104-161214723 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leber hereditary optic neuropathy, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 435.2;tongue: 591.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 668782720.5" "Group enriched" "Detected in all" "cerebral cortex: 128481983.4;heart muscle: 380617559.4;skeletal muscle: 118750158.4" "HPA055140, HPA061953" Enhanced Approved "Mitochondria,Calyx,Connecting piece" NA NA 37000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 68 Mitochondria "Calyx, Connecting piece" "HPA055140: , HPA061953: " "unprognostic (5.07e-3)" "unprognostic (1.61e-2)" "unprognostic (3.03e-1)" "unprognostic (2.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.40e-2)" "unprognostic (2.34e-1)" "potential prognostic favorable (5.35e-5)" "unprognostic (2.37e-1)" "unprognostic (7.41e-3)" "potential prognostic favorable (3.63e-8)" "unprognostic (3.41e-3)" "unprognostic (6.29e-3)" "unprognostic (1.12e-2)" "unprognostic (1.48e-1)" "unprognostic (6.28e-3)" "unprognostic (1.35e-2)" "unprognostic (4.12e-1)" "unprognostic (3.79e-2)" "unprognostic (4.08e-1)" "unprognostic (3.20e-1)" "unprognostic (9.60e-2)" "unprognostic (9.23e-2)" "unprognostic (9.06e-2)" "unprognostic (1.90e-1)" "unprognostic (6.72e-3)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" NDUFS4 "AQDQ, CI-18" ENSG00000164258 "NADH:ubiquinone oxidoreductase subunit S4" O43181 5 53560633-53683338 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 84064320.8" "Tissue enriched" "Detected in all" "heart muscle: 284661943.8" HPA003884 Supported Supported "Mitochondria,Equatorial segment,Perinuclear theca,Calyx" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 48 Mitochondria "Equatorial segment, Perinuclear theca, Calyx" "HPA003884: " "unprognostic (1.00e-1)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (1.37e-4)" "potential prognostic favorable (5.22e-6)" "unprognostic (5.55e-2)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (3.27e-1)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (3.09e-2)" "potential prognostic favorable (4.30e-10)" "unprognostic (1.55e-2)" "unprognostic (4.80e-3)" "unprognostic (1.61e-1)" "unprognostic (1.92e-2)" "unprognostic (7.65e-2)" "unprognostic (8.14e-2)" "unprognostic (1.02e-1)" "unprognostic (2.27e-1)" "unprognostic (9.07e-2)" "unprognostic (2.03e-2)" "unprognostic (6.92e-2)" "potential prognostic unfavorable (3.45e-4)" "unprognostic (5.39e-2)" "unprognostic (4.70e-2)" "unprognostic (2.80e-2)" "unprognostic (3.17e-1)" "unprognostic (5.23e-3)" "unprognostic (8.01e-2)" "unprognostic (1.36e-1)" "unprognostic (2.98e-1)" NDUFV1 CI-51K ENSG00000167792 "NADH:ubiquinone oxidoreductase core subunit V1" P49821 11 67605653-67612554 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 465.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 971753345.2" "Tissue enhanced" "Detected in all" "heart muscle: 570650268.6" "HPA045211, HPA075051" Enhanced Approved Mitochondria,Cytosol No No 87000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 64 Mitochondria Cytosol "HPA045211: , HPA075051: " "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.48e-2)" "unprognostic (7.39e-2)" "unprognostic (1.23e-1)" "unprognostic (4.66e-2)" "unprognostic (4.13e-2)" "unprognostic (1.31e-1)" "unprognostic (4.87e-3)" "unprognostic (8.90e-3)" "unprognostic (1.88e-2)" "potential prognostic favorable (1.15e-8)" "unprognostic (1.89e-1)" "potential prognostic favorable (6.64e-5)" "unprognostic (4.96e-2)" "unprognostic (1.36e-1)" "unprognostic (7.35e-2)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-1)" "unprognostic (4.39e-1)" "unprognostic (5.79e-2)" "unprognostic (1.12e-1)" "unprognostic (1.20e-1)" "unprognostic (2.40e-2)" "unprognostic (3.18e-2)" "unprognostic (3.87e-2)" "unprognostic (3.22e-1)" "unprognostic (3.79e-2)" "unprognostic (1.05e-1)" "unprognostic (2.19e-1)" "unprognostic (8.87e-2)" NDUFV2 CI-24k ENSG00000178127 "NADH:ubiquinone oxidoreductase core subunit V2" P19404 18 9102630-9134345 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "Oxidoreductase, Translocase" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 133.9;Enteric stem cells: 115.1;Enteric transient amplifying cells: 147.5;Enterocytes: 173.1;Epididymal basal cells: 113.1;Epididymal clear cells: 122.5;Epididymal efferent duct ciliated cells: 122.1;Epididymal principal cells: 94.1;Gastric chief cells: 88.5;Goblet cells: 87.5;Paneth cells: 108.3;Parietal cells: 244.0" "Cell type enhanced" "Detected in many" "Enterocytes: 173.1;Gastric glandular cells: 244.0;Proliferating cells: 147.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 470569011.3" "Group enriched" "Detected in all" "heart muscle: 850640002.2;kidney: 213123219.8;skeletal muscle: 233614462.5" "HPA003404, HPA077896" Enhanced Approved Nucleoplasm,Mitochondria,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 15: Non-specific - Protein processing" 110 Mitochondria "Nucleoplasm, Cytosol" "HPA003404: , HPA077896: " "unprognostic (1.06e-2)" "unprognostic (4.92e-1)" "unprognostic (2.31e-1)" "unprognostic (7.99e-3)" "unprognostic (1.28e-1)" "unprognostic (1.48e-1)" "unprognostic (7.46e-3)" "unprognostic (1.51e-3)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (5.98e-2)" "unprognostic (7.95e-3)" "unprognostic (2.22e-2)" "unprognostic (3.51e-2)" "unprognostic (1.55e-1)" "unprognostic (4.91e-2)" "unprognostic (3.42e-2)" "unprognostic (9.68e-2)" "unprognostic (2.11e-1)" "unprognostic (8.07e-2)" "unprognostic (2.95e-3)" "unprognostic (4.03e-1)" "unprognostic (1.22e-1)" "unprognostic (8.32e-2)" "unprognostic (4.88e-2)" "unprognostic (4.72e-2)" "unprognostic (3.12e-1)" "unprognostic (9.02e-2)" "unprognostic (4.03e-1)" "unprognostic (2.35e-1)" "unprognostic (5.88e-2)" "unprognostic (1.78e-1)" NDUFV3 CI-10k ENSG00000160194 "NADH:ubiquinone oxidoreductase subunit V3" P56181 21 42879644-42913304 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Respiratory chain, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 30.8" "Cell type enriched" "Detected in all" 4 "Late spermatids: 2576.9" "Cell type enriched" "Detected in all" 5 "Spermatogenic cell types: 2576.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 40236629.0" "Tissue enriched" "Detected in all" "heart muscle: 358706607.0" "HPA019791, HPA020463, HPA030427, CAB034142" Enhanced Enhanced Mitochondria NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 52: Non-specific - Cellular respiration" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 28 Mitochondria "CAB034142: , HPA019791: , HPA020463: , HPA030427: " "unprognostic (4.69e-3)" "unprognostic (3.43e-2)" "unprognostic (2.55e-1)" "unprognostic (3.04e-2)" "unprognostic (1.01e-1)" "unprognostic (5.04e-3)" "unprognostic (3.50e-1)" "unprognostic (4.02e-1)" "unprognostic (8.32e-2)" "unprognostic (3.35e-2)" "unprognostic (8.75e-2)" "unprognostic (4.52e-3)" "unprognostic (1.56e-2)" "unprognostic (3.29e-1)" "unprognostic (3.14e-1)" "unprognostic (2.69e-1)" "unprognostic (3.73e-3)" "unprognostic (9.91e-2)" "unprognostic (2.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.02e-3)" "unprognostic (1.28e-3)" "unprognostic (2.68e-1)" "unprognostic (4.55e-1)" "unprognostic (3.33e-2)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (6.73e-4)" "unprognostic (1.73e-1)" "unprognostic (3.97e-2)" NECAB1 EFCBP1 ENSG00000123119 "N-terminal EF-hand calcium binding protein 1" Q8N987 8 90791741-90959393 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 49.7;choroid plexus: 15.9" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 127.6;Alveolar cells type 2: 145.5;Brain excitatory neurons: 208.5;Brain inhibitory neurons: 250.6;Cardiomyocytes: 354.2;Choroid plexus epithelial cells: 566.3;Epicardial cells: 213.8;Neutrophils: 214.9;Oligodendrocytes: 360.7;Other brain neurons: 152.5;Pituicytes/FSCs: 267.9;Podocytes: 454.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 566.3;Glial cells: 360.7;Myocytes: 354.2;Renal nephron cells: 454.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 4905693.2;Glomeruli: 2382357.1;Microglia and Neuropil: 4609527.5;Neurons: 5667686.8" "Tissue enriched" "Detected in many" "cerebral cortex: 22851643.5" "HPA023252, HPA023629, HPA025963, HPA031262, CAB068208, CAB068209, CAB068210" Enhanced Supported Supported "Nucleoplasm,Mitotic spindle,Primary cilium,Primary cilium tip,Cytosol" Yes NA "Cluster 78: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 11 Nucleoplasm "Mitotic spindle, Primary cilium, Primary cilium tip, Cytosol" "CAB068208: , CAB068209: , CAB068210: , HPA023252: , HPA023629: , HPA025963: , HPA031262: " "unprognostic (1.63e-1)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (2.78e-1)" "unprognostic (1.56e-3)" "potential prognostic favorable (9.16e-4)" "potential prognostic favorable (6.45e-4)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (9.58e-3)" "unprognostic (1.85e-3)" "unprognostic (6.72e-3)" "unprognostic (7.31e-2)" NECAP2 FLJ10420 ENSG00000157191 "NECAP endocytosis associated 2" Q9NVZ3 1 16440721-16460078 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 153.8;Hofbauer cells: 188.8;Kupffer cells: 167.1" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 188.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 12682751.9;T-cells: 8973662.8" "Group enriched" "Detected in many" "bone marrow: 10814836.8;lymphoid tissue: 17821507.2;ovary: 4581284.6" HPA028077 Approved Approved "Endoplasmic reticulum" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 26 "Endoplasmic reticulum" "HPA028077: " "unprognostic (3.03e-2)" "unprognostic (6.83e-2)" "unprognostic (1.05e-2)" "unprognostic (4.71e-2)" "unprognostic (1.04e-1)" "unprognostic (1.41e-1)" "unprognostic (1.85e-1)" "unprognostic (1.88e-1)" "unprognostic (8.95e-2)" "unprognostic (5.31e-2)" "validated prognostic favorable (3.43e-6)" "validated prognostic favorable (8.50e-4)" "unprognostic (3.08e-1)" "potential prognostic unfavorable (1.67e-5)" "unprognostic (1.04e-2)" "unprognostic (7.10e-2)" "unprognostic (1.66e-3)" "unprognostic (3.18e-2)" "unprognostic (2.20e-2)" "unprognostic (8.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.88e-1)" "unprognostic (2.03e-2)" "unprognostic (1.63e-1)" "unprognostic (1.87e-1)" "unprognostic (9.82e-3)" "unprognostic (1.21e-1)" "unprognostic (2.54e-1)" "unprognostic (2.24e-1)" "unprognostic (2.93e-1)" "unprognostic (9.68e-3)" NECTIN2 "CD112, HVEB, Nectin-2, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 597.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 597.7" "Cell type enhanced" "Detected in many" "endothelial cell: 130.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Colon - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 6174167.9" "Low tissue specificity" "Detected in all" "HPA012374, HPA012759, CAB026138" Enhanced Approved "Vesicles,Plasma membrane,Mitotic spindle" Yes Yes 4300000 "Cluster 19: Eosinophils - Unknown function" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 66: Non-specific - Mitochondria" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 26 Vesicles "Plasma membrane, Mitotic spindle" "CAB026138: , HPA012374: , HPA012759: " "unprognostic (1.21e-2)" "unprognostic (1.20e-2)" "unprognostic (1.38e-1)" "unprognostic (2.14e-2)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.40e-2)" "unprognostic (2.34e-2)" "unprognostic (2.73e-1)" "unprognostic (1.66e-2)" "unprognostic (2.91e-1)" "unprognostic (2.11e-1)" "unprognostic (1.68e-2)" "unprognostic (3.38e-3)" "unprognostic (1.79e-1)" "unprognostic (3.05e-1)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (3.60e-2)" "unprognostic (1.72e-1)" "unprognostic (8.19e-2)" "unprognostic (2.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.52e-1)" "unprognostic (1.40e-1)" "unprognostic (2.85e-1)" "unprognostic (2.00e-1)" "unprognostic (3.25e-1)" "unprognostic (1.39e-1)" NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 40.7;esophagus: 96.0;salivary gland: 32.2;skin 1: 110.2;vagina: 56.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 743.5;Esophageal suprabasal cells: 312.2;Extravillous trophoblasts: 115.1;Ocular epithelial cells: 247.1;Prostatic hillock cells: 174.2;Suprabasal keratinocytes: 233.0;Syncytiotrophoblasts: 571.5;Urothelial cells: 241.4" "Group enriched" "Detected in many" 4 "Apical squamous epithelial cells: 743.5;Barrier epithelial cells: 247.1;Suprabasal cells: 312.2;Trophoblast cells: 571.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 112.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 27.9" "Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Keratinocytes: 18960977.8" "Group enriched" "Detected in some" "salivary gland: 1038641.1;skin: 1756359.9" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" Receptor No No 2300000 "Cluster 22: Eosinophils - Transcription" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 6 "Plasma membrane" "HPA010775: " "unprognostic (1.86e-1)" "potential prognostic unfavorable (3.01e-4)" "unprognostic (4.27e-1)" "unprognostic (1.77e-1)" "unprognostic (9.91e-2)" "unprognostic (8.36e-2)" "unprognostic (1.83e-1)" "unprognostic (1.55e-2)" "unprognostic (1.01e-1)" "unprognostic (1.35e-3)" "unprognostic (1.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.92e-1)" "unprognostic (2.21e-2)" "unprognostic (1.17e-2)" "unprognostic (3.19e-1)" "unprognostic (2.24e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-2)" "unprognostic (4.56e-3)" "unprognostic (5.30e-2)" "unprognostic (2.90e-1)" "unprognostic (2.79e-2)" "unprognostic (1.02e-1)" NEDD8 Nedd-8 ENSG00000129559 "NEDD8 ubiquitin like modifier" Q15843 14 24216857-24232367 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric chief cells: 150.7;Parietal cells: 182.1" "Cell type enhanced" "Detected in many" "Gastric glandular cells: 182.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004082, HPA027583, HPA060254" Uncertain Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 1100000 "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 100 Nucleoplasm "Golgi apparatus, Cytosol" "CAB004082: , HPA027583: , HPA060254: " "unprognostic (1.62e-1)" "unprognostic (5.37e-2)" "unprognostic (3.71e-2)" "unprognostic (9.34e-3)" "unprognostic (3.33e-2)" "unprognostic (1.40e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" "potential prognostic unfavorable (1.45e-4)" "potential prognostic unfavorable (3.91e-4)" "potential prognostic favorable (5.90e-6)" "unprognostic (3.86e-2)" "unprognostic (1.72e-1)" "unprognostic (7.68e-3)" "potential prognostic unfavorable (2.01e-4)" "unprognostic (7.97e-3)" "unprognostic (7.12e-3)" "unprognostic (1.48e-2)" "unprognostic (2.43e-1)" "unprognostic (1.34e-1)" "unprognostic (2.69e-1)" "unprognostic (7.68e-2)" "unprognostic (6.57e-2)" "unprognostic (2.72e-1)" "unprognostic (1.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.55e-1)" "unprognostic (1.27e-2)" "unprognostic (1.44e-1)" "unprognostic (1.36e-1)" "unprognostic (2.73e-1)" NEFL "CMT1F, CMT2E, NF68, NFL, PPP1R110" ENSG00000277586 "Neurofilament light chain" P07196 8 24950955-24956721 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "brain: 298.8;retina: 82.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 24.5;Brain excitatory neurons: 76.1;Brain inhibitory neurons: 52.9;Corticotrophs: 98.6;Esophageal suprabasal cells: 26.1;Gonadotrophs: 32.0;Oocytes: 50.7;Other brain neurons: 114.2;Retinal ganglion cells: 92.7;Suprabasal keratinocytes: 23.0" "Cell type enhanced" "Detected in many" "Neuronal cells: 114.2;Oocytes: 50.7;Pituitary endocrine cells: 98.6" "Cell type enhanced" "Detected in all" "lower rhombic lip: 444.3;thalamic excitatory: 281.4" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 84.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "memory CD4 T-cell: 11.2" "Lineage enriched" "Detected in single" 113 "T-cells: 11.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 73.2" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 2080384483.8;Microglia and Neuropil: 1038112079.8" "Tissue enriched" "Detected in many" "cerebral cortex: 1945269655.0" "HPA014850, HPA015021" Enhanced Supported Approved "Nucleoplasm,Intermediate filaments,Midbody" Yes NA 720000 "Cluster 39: T-cells - T-cell receptor" "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 98: Neurons - Neurotransmission & signaling" 93 "Nucleoplasm, Intermediate filaments" Midbody "HPA014850: , HPA015021: " "unprognostic (4.49e-2)" "unprognostic (2.78e-2)" "unprognostic (1.63e-1)" "unprognostic (6.17e-2)" "unprognostic (5.79e-2)" "unprognostic (3.04e-2)" "unprognostic (5.92e-2)" "unprognostic (1.78e-1)" "unprognostic (3.72e-1)" "unprognostic (2.31e-3)" "unprognostic (1.57e-3)" "unprognostic (6.50e-2)" "unprognostic (1.23e-1)" "unprognostic (6.24e-2)" "unprognostic (2.51e-1)" "unprognostic (4.38e-2)" "unprognostic (1.88e-1)" "unprognostic (4.39e-1)" NEFM "NEF3, NF-M, NFM" ENSG00000104722 "Neurofilament medium chain" P07197 8 24913758-24919098 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "brain: 308.0;retina: 84.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 49.8;Breast myoepithelial cells: 42.2;Corticotrophs: 114.9;Early spermatids: 81.4;Gonadotrophs: 151.8;Late primary spermatocytes: 121.9;Late spermatids: 178.3;Oocytes: 50.7;Other brain neurons: 54.5;Pancreatic islet cells: 58.5;Retinal ganglion cells: 135.2;Thymic myoid cells: 58.5" "Cell type enhanced" "Detected in many" "Neuronal cells: 135.2;Pituitary endocrine cells: 151.8;Spermatogenic cell types: 178.3" "Cell type enhanced" "Detected in all" "lower rhombic lip: 249.4;thalamic excitatory: 202.2" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 16.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 56.7;Neuroblastoma: 79.7;Rhabdoid: 129.8" "Colon - Colon enteroendocrine cells, Pituitary gland - Gonadotropes, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 967531721.1;Microglia and Neuropil: 618546744.8" "Tissue enriched" "Detected in many" "cerebral cortex: 2210790682.6" "CAB010900, CAB012976, HPA022845, HPA023138" Enhanced Enhanced "Intermediate filaments" Yes NA 800000 "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 43 "Intermediate filaments" "CAB010900: , CAB012976: , HPA022845: , HPA023138: " "unprognostic (1.15e-1)" "unprognostic (4.20e-1)" "unprognostic (1.20e-1)" "unprognostic (1.90e-1)" "unprognostic (1.84e-1)" "unprognostic (1.67e-2)" "unprognostic (1.17e-1)" "unprognostic (2.09e-1)" "unprognostic (6.99e-2)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.11e-2)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" NEGR1 "IGLON4, KILON, MGC46680, Ntra" ENSG00000172260 "Neuronal growth regulator 1" Q7Z3B1 1 71395943-72282539 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1921.0;Brain inhibitory neurons: 1564.4;Cone photoreceptor cells: 1409.7;Corticotrophs: 1720.7;Fibro-adipogenic progenitors: 4285.0;Fibroblasts: 1059.9;Lactotrophs: 1631.0;Leydig cells: 2587.9;Other brain neurons: 1312.9;Retinal amacrine cells: 1246.0;Rod photoreceptor cells: 2355.1;Schwann cells: 1373.2;Somatotrophs: 1267.5;Thymocytes: 1311.1;Thyrotrophs: 2372.6" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 4285.0;Leydig cells: 2587.9;Neuronal cells: 2355.1;Pituitary endocrine cells: 2372.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pancreas - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 46779256.6;Microglia and Neuropil: 27207371.6" "Tissue enriched" "Detected in all" "cerebral cortex: 338774353.9" HPA011894 Uncertain Approved "Vesicles,Actin filaments,Cytosol" NA NA 14000000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 "Vesicles, Actin filaments, Cytosol" "HPA011894: " "unprognostic (8.82e-3)" "unprognostic (1.96e-1)" "unprognostic (6.68e-3)" "unprognostic (2.92e-1)" "unprognostic (1.01e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-3)" "potential prognostic favorable (9.40e-4)" "unprognostic (1.72e-2)" "unprognostic (3.33e-2)" "unprognostic (2.63e-1)" "unprognostic (4.62e-1)" "unprognostic (7.46e-2)" "unprognostic (4.73e-2)" "unprognostic (1.32e-1)" "unprognostic (6.64e-2)" "unprognostic (1.24e-2)" "unprognostic (2.03e-2)" "unprognostic (7.23e-3)" "unprognostic (7.37e-2)" "unprognostic (8.68e-2)" NEK1 "KIAA1901, NY-REN-55" ENSG00000137601 "NIMA related kinase 1" Q96PY6 4 169369704-169612632 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Cilium biogenesis/degradation, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Amyotrophic lateral sclerosis, Ciliopathy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 458.3;Somatotrophs: 447.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 4107585.6" "Tissue enriched" "Detected in many" 1 "intestine: 128654461.2" "HPA020873, HPA040413" Approved Supported "Nucleoplasm,Primary cilium,Centriolar satellite,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 103: Non-specific - Basic cellular processes" 35 Nucleoplasm "Primary cilium, Centriolar satellite, Cytosol" "HPA020873: , HPA040413: " "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "unprognostic (4.03e-2)" "unprognostic (1.11e-1)" "unprognostic (2.81e-1)" "unprognostic (3.74e-1)" "unprognostic (9.29e-2)" "unprognostic (1.11e-1)" "unprognostic (3.21e-1)" "unprognostic (1.05e-3)" "validated prognostic favorable (8.57e-7)" "validated prognostic favorable (2.73e-4)" "unprognostic (1.25e-1)" "unprognostic (4.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.30e-1)" "unprognostic (3.26e-1)" "unprognostic (1.12e-1)" "unprognostic (1.06e-1)" "unprognostic (2.55e-2)" "unprognostic (2.10e-1)" "unprognostic (1.07e-2)" "unprognostic (9.85e-2)" "unprognostic (1.30e-1)" "unprognostic (3.26e-2)" "unprognostic (8.35e-2)" "unprognostic (6.93e-2)" "unprognostic (2.20e-1)" "unprognostic (2.02e-2)" "unprognostic (8.65e-2)" NEK2 "NEK2A, NLK1, PPP1R111, RP67" ENSG00000117650 "NIMA related kinase 2" P51955 1 211658657-211675630 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 16.7;lymphoid tissue: 17.9;testis: 62.8" "Cell type enriched" "Detected in many" 4 "Late primary spermatocytes: 413.5" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 413.5" "Cell type enhanced" "Detected in some" "ependymal cell: 2.5;hippocampal CA4: 2.6;upper-layer intratelencephalic: 1.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in many" "cerebellum: 5.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB017530, HPA064967" Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Primary cilium,Centrosome,Basal body" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 48 "Nucleoplasm, Centrosome" "Cytokinetic bridge, Primary cilium, Basal body" "CAB017530: , HPA064967: " "unprognostic (3.15e-3)" "unprognostic (3.28e-2)" "unprognostic (1.42e-1)" "unprognostic (1.64e-1)" "unprognostic (6.47e-2)" "unprognostic (6.65e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-2)" "unprognostic (8.54e-2)" "potential prognostic unfavorable (1.83e-4)" "validated prognostic unfavorable (1.77e-7)" "validated prognostic unfavorable (6.90e-6)" "potential prognostic unfavorable (1.70e-8)" "validated prognostic unfavorable (1.06e-6)" "validated prognostic unfavorable (1.06e-6)" "potential prognostic unfavorable (6.66e-5)" "unprognostic (1.98e-3)" "unprognostic (3.77e-2)" "unprognostic (2.41e-1)" "unprognostic (1.87e-1)" "unprognostic (3.81e-1)" "potential prognostic unfavorable (2.35e-4)" "unprognostic (6.18e-3)" "unprognostic (6.85e-2)" "unprognostic (2.73e-2)" "unprognostic (2.15e-2)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.31e-1)" "unprognostic (8.97e-2)" NEK3 "HSPK36, MGC29949" ENSG00000136098 "NIMA related kinase 3" P51956 13 52132639-52159861 "Enzymes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 121.7" "Cell type enhanced" "Detected in many" "Glial cells: 121.7" "Cell type enhanced" "Detected in all" "endothelial cell: 123.8;oligodendrocyte: 159.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 226930.1;Fallopian tube cells: 231386.2;Granulosa cells: 192344.9;Large ducts: 197950.4" "Group enriched" "Detected in some" 14062 "intestine: 568798.3;Stomach: 2243602.5" "HPA019062, HPA043230" Enhanced Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 19: Non-specific - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Microtubules "Plasma membrane, Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA019062: , HPA043230: " "unprognostic (6.93e-2)" "unprognostic (5.91e-2)" "unprognostic (2.50e-1)" "unprognostic (8.82e-2)" "unprognostic (9.24e-2)" "unprognostic (1.01e-1)" "unprognostic (1.18e-2)" "unprognostic (6.75e-3)" "unprognostic (1.25e-1)" "unprognostic (7.93e-2)" "unprognostic (4.94e-2)" "unprognostic (8.88e-2)" "unprognostic (5.54e-2)" "unprognostic (2.15e-1)" "unprognostic (3.92e-2)" "unprognostic (6.94e-2)" "unprognostic (8.35e-2)" "unprognostic (1.55e-2)" "unprognostic (1.72e-1)" "unprognostic (3.56e-2)" "unprognostic (4.08e-2)" "unprognostic (5.68e-2)" "unprognostic (3.58e-2)" "unprognostic (5.85e-3)" "unprognostic (2.35e-2)" "unprognostic (4.75e-2)" "unprognostic (2.27e-1)" "unprognostic (8.18e-3)" "unprognostic (1.34e-2)" "unprognostic (4.34e-2)" "unprognostic (5.86e-3)" NEK5 ENSG00000197168 "NIMA related kinase 5" Q6P3R8 13 52033611-52129092 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.1;testis: 10.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 152.4;Endometrial ciliated cells: 188.0;Ependymal cells: 663.9;Epididymal efferent duct ciliated cells: 164.5;Fallopian tube ciliated cells: 270.0;Respiratory ciliated cells: 469.4" "Cell type enriched" "Detected in many" 8 "Ciliated cells: 663.9" "Cell type enriched" "Detected in all" 5 "ependymal cell: 738.2" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Macrophages: 1855424.8" "Group enriched" "Detected in some" 3933 "bone marrow: 263832.6;lymphoid tissue: 522794.7" "HPA035565, HPA037016, HPA041399" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 Nucleoplasm Cytosol "HPA035565: , HPA037016: , HPA041399: " "unprognostic (1.37e-1)" "unprognostic (1.09e-1)" "unprognostic (6.54e-3)" "unprognostic (1.49e-1)" "unprognostic (1.42e-2)" "unprognostic (4.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.01e-2)" "unprognostic (1.05e-1)" "unprognostic (7.09e-3)" "unprognostic (5.44e-2)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (7.12e-3)" "unprognostic (9.55e-2)" "unprognostic (1.43e-1)" "unprognostic (6.04e-2)" NEK7 ENSG00000151414 "NIMA related kinase 7" Q8TDX7 1 198156994-198322420 "Enzymes, Predicted intracellular proteins, Transporters" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 131.4" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 612.2;Neutrophils: 794.2" "Cell type enhanced" "Detected in all" "Neutrophils: 794.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA015520, HPA018193" Approved Supported Nucleoplasm Yes No "Cluster 1: T-cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 97 Nucleoplasm "HPA015520: , HPA018193: " "unprognostic (6.34e-3)" "unprognostic (1.65e-1)" "unprognostic (6.22e-2)" "unprognostic (2.20e-2)" "unprognostic (1.04e-1)" "unprognostic (3.91e-2)" "unprognostic (1.21e-1)" "unprognostic (3.20e-1)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (6.12e-7)" "unprognostic (1.89e-2)" "unprognostic (3.30e-2)" "unprognostic (1.67e-2)" "unprognostic (5.33e-1)" "unprognostic (3.47e-1)" "unprognostic (1.65e-1)" "unprognostic (1.94e-1)" "unprognostic (8.05e-2)" "unprognostic (4.71e-2)" "potential prognostic unfavorable (6.72e-4)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (7.02e-2)" "unprognostic (1.33e-1)" "unprognostic (1.40e-1)" "unprognostic (1.64e-1)" "unprognostic (8.06e-2)" "unprognostic (5.57e-3)" "unprognostic (1.84e-1)" "unprognostic (2.60e-3)" "unprognostic (9.61e-2)" NEK8 NPHP9 ENSG00000160602 "NIMA related kinase 8" Q86SG6 17 28725897-28743455 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Disease variant, Nephronophthisis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 49.7;pDCs: 120.6" "Cell type enhanced" "Detected in many" "dendritic cells: 120.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 14.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 52595.7;Fallopian tube cells: 93413.0;Granulosa cells: 159083.4;Oocytes: 46709.6" "Tissue enriched" "Detected in single" 46 "lymphoid tissue: 4590.2" "HPA040661, HPA040679" Approved Approved "Nuclear speckles,Microtubules,Mitotic spindle,Primary cilium" Yes NA "Cluster 41: Basophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 23 Microtubules "Nuclear speckles, Mitotic spindle, Primary cilium" "HPA040661: , HPA040679: " "unprognostic (3.92e-2)" "unprognostic (9.29e-2)" "unprognostic (7.04e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (5.56e-4)" "unprognostic (2.02e-2)" "unprognostic (7.64e-2)" "potential prognostic unfavorable (8.77e-4)" "unprognostic (2.13e-2)" "unprognostic (7.72e-2)" "unprognostic (2.02e-1)" "unprognostic (7.29e-3)" "potential prognostic favorable (8.91e-4)" "unprognostic (1.11e-2)" "unprognostic (2.88e-2)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (3.38e-1)" "unprognostic (2.89e-2)" "unprognostic (1.65e-1)" "unprognostic (1.79e-1)" "unprognostic (1.66e-3)" "unprognostic (4.44e-2)" "unprognostic (2.23e-1)" "unprognostic (4.22e-2)" "unprognostic (6.55e-2)" "unprognostic (1.23e-1)" "unprognostic (3.09e-1)" "unprognostic (2.62e-1)" "unprognostic (5.24e-2)" "unprognostic (3.38e-2)" NEPRO "C3orf17, DKFZP434F2021, NET17" ENSG00000163608 "Nucleolus and neural progenitor protein" Q6NW34 3 113002444-113019861 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 3321113.3" "Tissue enriched" "Detected in single" 37191 "intestine: 3719094.2" HPA069654 Supported Nucleoplasm,Nucleoli Yes No "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 21 "Nucleoplasm, Nucleoli" "HPA069654: " "unprognostic (1.33e-1)" "unprognostic (2.23e-1)" "unprognostic (1.93e-1)" "unprognostic (2.01e-3)" "unprognostic (1.83e-1)" "unprognostic (1.17e-1)" "unprognostic (1.16e-2)" "unprognostic (5.59e-2)" "unprognostic (1.32e-1)" "potential prognostic favorable (2.09e-5)" "unprognostic (2.51e-1)" "unprognostic (2.03e-2)" "unprognostic (7.40e-3)" "unprognostic (1.81e-1)" "unprognostic (4.21e-1)" "unprognostic (1.74e-1)" "unprognostic (5.04e-2)" "unprognostic (1.35e-2)" "unprognostic (1.18e-1)" "unprognostic (5.57e-2)" "unprognostic (7.07e-3)" "unprognostic (9.48e-2)" "unprognostic (1.09e-2)" "unprognostic (3.46e-2)" "unprognostic (1.10e-1)" "unprognostic (2.46e-1)" "unprognostic (9.84e-2)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" NES FLJ21841 ENSG00000132688 Nestin P48681 1 156668763-156677407 "Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 151.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 83.5;Endometrial stromal cells: 25.9;Hepatic stellate cells: 64.5;Pericytes: 77.3;Podocytes: 141.2;Schwann cells: 81.1;Smooth muscle cells: 51.8;Vascular endothelial cells: 101.7;Vascular smooth muscle cells: 55.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 101.7;Glial cells: 81.1;Mural cells: 77.3;Renal nephron cells: 141.2;Secretory gland support: 83.5;Stellate cells: 64.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 29.3;endothelial cell: 73.9;vascular associated smooth muscle cell: 32.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 240.1;Skin Cutaneous Melanoma (TCGA): 186.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 313.9" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Glomeruli: 942741878.4" "Tissue enhanced" "Detected in all" "heart muscle: 299616851.6" "CAB005889, HPA006286, HPA007007, HPA026111, CAB058692" Enhanced Enhanced "Intermediate filaments" No No 51000 "Cluster 35: Non-specific - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 21 "Intermediate filaments" "CAB005889: , CAB058692: , HPA006286: , HPA007007: , HPA026111: " "unprognostic (3.27e-1)" "unprognostic (8.59e-2)" "unprognostic (4.76e-2)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (2.33e-1)" "unprognostic (1.51e-1)" "unprognostic (4.38e-3)" "unprognostic (1.92e-1)" "unprognostic (8.46e-3)" "validated prognostic favorable (1.50e-4)" "validated prognostic favorable (7.83e-4)" "unprognostic (3.47e-3)" "unprognostic (2.39e-2)" "unprognostic (2.59e-1)" "unprognostic (1.88e-2)" "unprognostic (2.65e-2)" "unprognostic (6.04e-2)" "unprognostic (2.02e-1)" "unprognostic (1.81e-1)" "unprognostic (3.50e-1)" "unprognostic (4.69e-2)" "unprognostic (1.83e-2)" "unprognostic (7.60e-2)" "unprognostic (1.47e-1)" "unprognostic (3.42e-2)" "unprognostic (1.23e-1)" "unprognostic (1.16e-1)" "unprognostic (2.30e-1)" "unprognostic (5.08e-2)" "unprognostic (1.74e-2)" NET1 "ARHGEF8, NET1A" ENSG00000173848 "Neuroepithelial cell transforming 1" Q7Z628 10 5412557-5459056 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 776.6;Ocular epithelial cells: 425.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 776.6" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 218.3;endothelial cell: 415.6;vascular associated smooth muscle cell: 219.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 8.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA020068 Uncertain Approved Nucleoplasm,Vesicles Yes Yes "Cluster 31: T-cells - T-cell receptor" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 9 Nucleoplasm Vesicles "HPA020068: " "unprognostic (7.70e-2)" "unprognostic (3.26e-3)" "potential prognostic favorable (4.80e-4)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (8.53e-3)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.28e-4)" "unprognostic (1.94e-1)" "unprognostic (4.49e-2)" "potential prognostic favorable (2.20e-5)" "unprognostic (2.26e-3)" "unprognostic (6.78e-2)" "potential prognostic unfavorable (5.63e-5)" "unprognostic (1.08e-3)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (9.67e-3)" "unprognostic (4.25e-2)" "unprognostic (2.91e-2)" "unprognostic (5.22e-3)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (2.15e-1)" "unprognostic (2.44e-1)" "unprognostic (4.71e-2)" "unprognostic (2.91e-1)" "unprognostic (2.31e-1)" "unprognostic (1.03e-1)" "unprognostic (9.60e-2)" "unprognostic (1.67e-1)" "unprognostic (4.32e-2)" NEU3 ENSG00000162139 "Neuraminidase 3" Q9UQ49 11 74988279-75018893 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 53.0;Cone photoreceptor cells: 84.9;Early primary spermatocytes: 52.5;Myonuclei: 90.3" "Cell type enhanced" "Detected in many" "Myocytes: 90.3;Neuronal cells: 84.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 655464.4;Microglia and Neuropil: 837191.5" "Tissue enriched" "Detected in some" "cerebral cortex: 1512234.2" "HPA038729, HPA070381" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 5 Nucleoplasm Vesicles "HPA038729: , HPA070381: " "unprognostic (9.56e-2)" "unprognostic (8.81e-2)" "unprognostic (3.02e-1)" "unprognostic (8.22e-2)" "unprognostic (1.97e-1)" "unprognostic (4.76e-2)" "unprognostic (2.67e-1)" "potential prognostic favorable (2.40e-4)" "unprognostic (1.94e-1)" "unprognostic (4.29e-3)" "unprognostic (1.09e-1)" "unprognostic (2.82e-1)" "unprognostic (1.04e-1)" "unprognostic (1.36e-2)" "unprognostic (2.16e-2)" "unprognostic (1.65e-1)" "unprognostic (6.76e-3)" "unprognostic (3.97e-3)" "unprognostic (1.80e-1)" "unprognostic (3.01e-2)" "unprognostic (9.18e-2)" "unprognostic (4.42e-3)" "potential prognostic unfavorable (8.99e-4)" "unprognostic (9.63e-3)" "potential prognostic favorable (9.29e-5)" "unprognostic (4.38e-3)" "unprognostic (2.77e-2)" "unprognostic (2.47e-1)" "unprognostic (7.91e-2)" "unprognostic (9.52e-2)" "unprognostic (1.54e-1)" NEXMIF "KIAA2022, KIDLIA, MRX98, XPN" ENSG00000050030 "Neurite extension and migration factor" Q5QGS0 X 74732856-74925472 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 127.3;Brain inhibitory neurons: 157.0;Corticotrophs: 114.9;Distal convoluted tubule cells: 120.5;Gonadotrophs: 103.5;Lactotrophs: 187.4;Oligodendrocyte progenitor cells: 98.0;Other brain neurons: 155.8;Retinal amacrine cells: 129.1;Somatotrophs: 291.6;Thyrotrophs: 159.0" "Cell type enhanced" "Detected in many" "Neuronal cells: 157.0;Pituitary endocrine cells: 291.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.6;Neuroblastoma: 1.3" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 167 "Neurons: 16679.8" "Tissue enriched" "Detected in single" 597 "skin: 59740.3" HPA000407 Uncertain Supported Nucleoplasm,Midbody,Cytosol Yes NA "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 11: Neuronal - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 1 Nucleoplasm "Midbody, Cytosol" "HPA000407: " "unprognostic (1.83e-1)" "unprognostic (6.97e-2)" "unprognostic (1.07e-1)" NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 29.1;lymphoid tissue: 18.8" "Cell type enriched" "Detected in many" 4 "Neutrophils: 560.4" "Cell type enriched" "Detected in many" 4 "Neutrophils: 560.4" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 38.4;leukocyte: 16.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.6" "Group enriched" "Detected in many" 4 "granulocytes: 90.6;monocytes: 48.2" "Cancer enriched" "Detected in single" 10 "Leukemia: 5.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Liver - Kupffer cells, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" "Neutrophils: 2369885.5" "Tissue enriched" "Detected in some" "lymphoid tissue: 152905.0" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "Plasma membrane, Cytosol" "HPA031812: " "unprognostic (6.23e-2)" "unprognostic (3.17e-2)" "unprognostic (2.56e-2)" "unprognostic (1.42e-1)" "unprognostic (4.51e-1)" "unprognostic (4.67e-1)" "unprognostic (2.59e-2)" "unprognostic (7.04e-2)" "unprognostic (4.41e-3)" "unprognostic (2.49e-1)" "unprognostic (1.67e-1)" "unprognostic (1.54e-1)" "unprognostic (3.68e-2)" "unprognostic (1.24e-1)" "unprognostic (2.09e-2)" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (1.70e-1)" "unprognostic (9.19e-2)" "unprognostic (3.35e-1)" "unprognostic (2.14e-1)" "unprognostic (3.71e-2)" "unprognostic (2.60e-1)" "unprognostic (8.62e-2)" "unprognostic (5.06e-2)" "potential prognostic favorable (2.81e-5)" "unprognostic (2.09e-1)" "unprognostic (3.95e-2)" "unprognostic (6.58e-2)" "unprognostic (3.74e-3)" NFAT5 "KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP" ENSG00000102908 "Nuclear factor of activated T cells 5" O94916 16 69565094-69704666 "Predicted intracellular proteins, Transcription factors" "DNA damage, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Neutrophils: 1704.9;Renal collecting duct principal cells: 1386.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Large ducts: 1064148.5" "Tissue enriched" "Detected in some" "intestine: 374919.9" "HPA051528, HPA057304, HPA069711, HPA074040" Approved Enhanced Nucleoplasm,Cytosol Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 12 Nucleoplasm Cytosol "HPA051528: , HPA057304: , HPA069711: , HPA074040: " "unprognostic (7.40e-2)" "unprognostic (7.49e-2)" "unprognostic (8.20e-2)" "unprognostic (3.66e-2)" "unprognostic (3.93e-1)" "unprognostic (1.06e-2)" "unprognostic (1.09e-1)" "unprognostic (3.69e-2)" "unprognostic (1.34e-1)" "validated prognostic favorable (2.82e-7)" "validated prognostic favorable (5.39e-4)" "unprognostic (4.18e-2)" "unprognostic (5.38e-2)" "unprognostic (4.21e-1)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (5.13e-2)" "unprognostic (2.38e-2)" "unprognostic (4.19e-3)" "unprognostic (7.38e-2)" "potential prognostic unfavorable (8.07e-4)" "unprognostic (2.54e-1)" "unprognostic (5.24e-2)" "unprognostic (4.12e-3)" "unprognostic (2.32e-1)" "unprognostic (2.20e-2)" "unprognostic (9.71e-3)" NFATC4 NFAT3 ENSG00000100968 "Nuclear factor of activated T cells 4" Q14934 14 24365673-24379604 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Astrocytes: 54.4;Bergmann glia: 39.5" "Cell type enriched" "Detected in some" 5 "Glial cells: 54.4" "Group enriched" "Detected in many" 6 "astrocyte: 51.7;Bergmann glia: 42.6;fibroblast: 64.9;pericyte: 76.1;vascular associated smooth muscle cell: 47.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 23.4" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 6330 "Oocytes: 632980.0" "Tissue enriched" "Detected in some" "intestine: 1863654.4" "HPA031641, CAB032859, HPA076526" Uncertain Supported "Nuclear speckles,Cytosol" No No "Cluster 75: Ovary - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 4 "Nuclear speckles, Cytosol" "CAB032859: , HPA031641: , HPA076526: " "unprognostic (9.21e-3)" "unprognostic (2.35e-1)" "unprognostic (1.57e-1)" "unprognostic (3.11e-2)" "unprognostic (9.22e-2)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (6.08e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (6.68e-2)" "unprognostic (1.44e-2)" "unprognostic (7.46e-2)" "unprognostic (1.28e-1)" "unprognostic (2.17e-2)" "unprognostic (4.24e-2)" "unprognostic (4.61e-3)" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (6.75e-2)" "unprognostic (4.42e-2)" "unprognostic (1.45e-1)" "unprognostic (4.24e-2)" "unprognostic (2.83e-2)" "unprognostic (4.95e-3)" "unprognostic (3.69e-1)" "unprognostic (2.21e-1)" "unprognostic (2.97e-2)" "unprognostic (1.07e-1)" "unprognostic (4.62e-2)" "unprognostic (1.49e-1)" NFKB2 "LYT-10, NF-kB2, p105, p49/p100, p52" ENSG00000077150 "Nuclear factor kappa B subunit 2" Q00653 10 102394110-102402524 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Mast cells: 93.3;monocytes: 80.6;Neutrophils: 258.6;Oocytes: 101.3;Pancreatic duct cells: 84.1" "Cell type enhanced" "Detected in many" "Neutrophils: 258.6" "Cell type enhanced" "Detected in some" "endothelial cell: 13.5;leukocyte: 9.8;vascular associated smooth muscle cell: 10.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 129.7" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 23230565.2" "Tissue enhanced" "Detected in many" "lymphoid tissue: 61167054.8" "HPA008422, CAB022098, HPA023900" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 43 "Nucleoplasm, Cytosol" "CAB022098: , HPA008422: , HPA023900: " "unprognostic (9.83e-2)" "unprognostic (9.75e-3)" "unprognostic (2.18e-3)" "unprognostic (1.66e-1)" "unprognostic (1.66e-2)" "unprognostic (8.13e-2)" "unprognostic (3.23e-3)" "unprognostic (6.83e-2)" "unprognostic (1.38e-1)" "unprognostic (9.92e-3)" "potential prognostic unfavorable (5.50e-4)" "unprognostic (2.31e-2)" "unprognostic (3.48e-3)" "unprognostic (1.02e-3)" "unprognostic (1.59e-1)" "unprognostic (9.04e-3)" "unprognostic (2.77e-2)" "unprognostic (3.19e-2)" "unprognostic (3.17e-1)" "unprognostic (2.20e-1)" "unprognostic (2.18e-1)" "unprognostic (2.12e-1)" "unprognostic (1.07e-3)" "unprognostic (4.38e-3)" "unprognostic (9.50e-2)" "potential prognostic favorable (3.88e-4)" "potential prognostic favorable (1.19e-4)" "unprognostic (3.84e-2)" "unprognostic (1.90e-1)" "unprognostic (2.20e-1)" "unprognostic (1.09e-2)" NFRKB "DKFZp547B2013, INO80G" ENSG00000170322 "Nuclear factor related to kappaB binding protein" Q6P4R8 11 129863636-129895590 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 85.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 2759252.5" "Group enriched" "Detected in some" "bone marrow: 719514.2;Stomach: 309577.9" "HPA007082, HPA007128" Approved Enhanced Nucleoplasm Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 24: Non-specific - Unknown function" "Cluster 26: Keratinocytes - Keratinization" 32 Nucleoplasm "HPA007082: , HPA007128: " "unprognostic (4.57e-3)" "unprognostic (2.38e-2)" "potential prognostic favorable (1.81e-4)" "unprognostic (1.07e-1)" "unprognostic (1.63e-1)" "unprognostic (1.76e-2)" "unprognostic (5.23e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (9.21e-2)" "unprognostic (3.91e-2)" "unprognostic (2.08e-3)" "unprognostic (4.88e-3)" "unprognostic (2.36e-1)" "unprognostic (1.20e-3)" "unprognostic (1.99e-1)" "unprognostic (4.21e-1)" "unprognostic (5.44e-3)" "unprognostic (8.23e-2)" "unprognostic (9.17e-2)" "unprognostic (2.33e-1)" "unprognostic (2.10e-1)" "unprognostic (1.61e-1)" "unprognostic (7.47e-3)" "unprognostic (7.91e-2)" "potential prognostic favorable (4.64e-4)" "unprognostic (9.11e-2)" "unprognostic (2.18e-3)" "unprognostic (1.08e-1)" "unprognostic (2.57e-1)" "unprognostic (3.57e-1)" "unprognostic (7.76e-2)" NFYB "CBF-A, HAP3, NF-YB" ENSG00000120837 "Nuclear transcription factor Y subunit beta" P25208 12 104117086-104138241 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Syncytiotrophoblasts: 486.0" "Cell type enriched" "Detected in all" 6 "Trophoblast cells: 486.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 795638.4;Neutrophils: 859134.3;T-cells: 524596.9" "Low tissue specificity" "Detected in many" "CAB004211, HPA065646" Supported Supported Nucleoplasm NA NA "Cluster 1: T-cells - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 22 Nucleoplasm "CAB004211: , HPA065646: " "unprognostic (7.37e-2)" "unprognostic (1.11e-2)" "unprognostic (3.73e-2)" "unprognostic (1.34e-2)" "unprognostic (3.79e-2)" "unprognostic (5.46e-2)" "unprognostic (1.05e-1)" "unprognostic (6.23e-2)" "unprognostic (1.08e-1)" "unprognostic (2.83e-1)" "unprognostic (6.04e-2)" "unprognostic (3.50e-2)" "unprognostic (2.81e-2)" "unprognostic (7.11e-2)" "unprognostic (4.13e-2)" "unprognostic (5.14e-2)" "unprognostic (3.82e-2)" "unprognostic (1.07e-1)" "unprognostic (3.19e-1)" "unprognostic (1.07e-1)" "unprognostic (3.32e-2)" "unprognostic (1.26e-1)" "unprognostic (1.85e-1)" "unprognostic (7.76e-2)" "unprognostic (1.53e-1)" "unprognostic (2.54e-2)" "unprognostic (2.95e-2)" "unprognostic (3.47e-3)" "unprognostic (3.77e-1)" "unprognostic (1.07e-1)" "unprognostic (9.70e-2)" NGDN "C14orf120, CANu1, DKFZP564O092, LCP5, lpd-2, NGD" ENSG00000129460 Neuroguidin Q8NEJ9 14 23469679-23509862 "Essential proteins, Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 119.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 2256673.9" "Tissue enriched" "Detected in single" 646 "lymphoid tissue: 64623.5" HPA000944 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 12 "Nucleoli, Mitochondria" Nucleoplasm "HPA000944: " "unprognostic (7.37e-3)" "unprognostic (2.18e-1)" "unprognostic (7.12e-2)" "unprognostic (3.42e-2)" "unprognostic (1.52e-1)" "unprognostic (1.89e-1)" "unprognostic (7.13e-2)" "unprognostic (1.85e-3)" "unprognostic (5.87e-3)" "unprognostic (6.00e-2)" "potential prognostic favorable (6.42e-7)" "unprognostic (1.10e-3)" "unprognostic (2.23e-1)" "unprognostic (3.34e-2)" "potential prognostic unfavorable (6.21e-6)" "unprognostic (1.89e-2)" "unprognostic (2.14e-3)" "unprognostic (1.34e-2)" "unprognostic (6.37e-2)" "unprognostic (1.61e-2)" "unprognostic (1.41e-1)" "unprognostic (1.63e-1)" "unprognostic (6.70e-2)" "unprognostic (7.01e-2)" "unprognostic (1.22e-1)" "unprognostic (4.58e-2)" "unprognostic (3.74e-2)" "unprognostic (2.69e-1)" "unprognostic (8.63e-2)" "unprognostic (9.91e-2)" "unprognostic (3.92e-2)" NGRN DSC92 ENSG00000182768 "Neugrin, neurite outgrowth associated" Q9NPE2 15 90265659-90275778 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 402.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 5.1;Brain inhibitory neurons: 4.5;Endometrial secretory cells: 2.9;Medullary thymic epithelial cells: 2.4;Oocytes: 4.6;Other brain neurons: 8.1" "Cell type enhanced" "Detected in some" "Neuronal cells: 8.1;Oocytes: 4.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 244036.1;Distal tubules: 75435.0;Large ducts: 113017.0;Neurons: 98395.3;Oocytes: 94430.7" "Group enriched" "Detected in some" "heart muscle: 452994.2;liver: 158214.8" "HPA041367, HPA076267" Supported Supported "Nucleoplasm,Cytokinetic bridge,Mitochondria" "Intracellular and membrane" "Developmental protein" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 58 Mitochondria "Nucleoplasm, Cytokinetic bridge" "HPA041367: , HPA076267: " "unprognostic (4.07e-3)" "unprognostic (9.11e-2)" "unprognostic (3.21e-1)" "unprognostic (8.28e-2)" "unprognostic (1.30e-3)" "unprognostic (2.65e-1)" "unprognostic (6.28e-2)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (3.00e-2)" "unprognostic (1.62e-1)" "unprognostic (1.42e-3)" "unprognostic (1.08e-1)" "unprognostic (1.04e-1)" "potential prognostic unfavorable (4.27e-7)" "unprognostic (3.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (4.16e-2)" "unprognostic (3.09e-3)" "unprognostic (1.53e-1)" "unprognostic (1.04e-1)" "unprognostic (7.52e-2)" "unprognostic (2.74e-1)" "unprognostic (4.58e-2)" "unprognostic (1.11e-1)" "unprognostic (4.69e-3)" "unprognostic (9.54e-2)" "unprognostic (6.02e-2)" "unprognostic (1.37e-1)" "unprognostic (4.32e-1)" NHLH2 "bHLHa34, HEN2, NSCL2" ENSG00000177551 "Nescient helix-loop-helix 2" Q02577 1 115836377-115843917 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.6;esophagus: 2.2;retina: 1.9;skin 1: 3.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 4.3;Brain excitatory neurons: 8.0;Breast myoepithelial cells: 11.2;Early primary spermatocytes: 5.3;Ependymal cells: 7.4;Epididymal basal cells: 4.3;Esophageal basal cells: 7.4;Esophageal suprabasal cells: 4.7;Oligodendrocytes: 7.3;Other brain neurons: 6.0;Retinal amacrine cells: 5.5;Retinal ganglion cells: 3.9;Suprabasal keratinocytes: 3.9;Thymic myoid cells: 19.0;Undifferentiated spermatogonia: 5.4" "Cell type enhanced" "Detected in some" "Basal cells: 7.4;Ciliated cells: 7.4;Glial cells: 7.3;Neuronal cells: 8.0;Secretory gland support: 11.2;Stromal cells: 19.0" "Cell type enhanced" "Detected in many" "thalamic excitatory: 27.7" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Neuroblastoma: 7.4" "Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA055238 Uncertain Approved "Nucleoplasm,Nuclear bodies" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 44: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 12 "Nuclear bodies" Nucleoplasm "HPA055238: " "unprognostic (1.04e-1)" "unprognostic (2.73e-2)" "unprognostic (9.06e-2)" NID1 "entactin, NID" ENSG00000116962 "Nidogen 1" P14543 1 235975830-236065109 "Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 216.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 295.2;Decidual stromal cells: 278.9;Endometrial stromal cells: 478.1;Fibro-adipogenic progenitors: 219.3;Fibroblasts: 541.9;Hepatic stellate cells: 335.6;Leydig cells: 272.4;Parietal cells: 175.0;Pericytes: 407.2;Peritubular myoid cells: 201.4;Smooth muscle cells: 186.6;Vascular smooth muscle cells: 157.0" "Cell type enhanced" "Detected in many" "Fibroblasts: 541.9;Mural cells: 407.2;Stellate cells: 335.6;Stromal cells: 478.1" "Cell type enhanced" "Detected in many" "fibroblast: 284.6;pericyte: 269.7;vascular associated smooth muscle cell: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16 "classical monocyte: 5.7;intermediate monocyte: 11.2;myeloid DC: 4.4;non-classical monocyte: 7.3" "Group enriched" "Detected in many" 17 "dendritic cells: 4.4;monocytes: 11.2" "Cancer enhanced" "Detected in many" "Rhabdoid: 108.0" "Adrenal gland - Fibroblasts, Minor Salivary Gland - Macrophages, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glomeruli: 884178290.3" "Low tissue specificity" "Detected in all" "CAB010044, HPA065049" Approved Uncertain "Vesicles,Mitotic spindle" "Secreted to extracellular matrix" "Cell adhesion" Yes NA 180000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 2 Vesicles "Mitotic spindle" "CAB010044: , HPA065049: " "unprognostic (9.66e-2)" "unprognostic (1.67e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-3)" "unprognostic (1.72e-1)" "unprognostic (4.16e-2)" "unprognostic (3.37e-1)" "unprognostic (2.99e-2)" "unprognostic (3.99e-2)" "unprognostic (2.06e-2)" "potential prognostic favorable (5.45e-4)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (8.48e-5)" "unprognostic (1.04e-3)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.50e-2)" "unprognostic (3.02e-3)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (4.11e-2)" "unprognostic (2.01e-2)" "unprognostic (1.65e-1)" "unprognostic (3.87e-1)" "unprognostic (2.25e-1)" "unprognostic (4.75e-2)" "unprognostic (3.89e-2)" "unprognostic (7.22e-2)" "unprognostic (8.78e-3)" "unprognostic (1.19e-1)" "unprognostic (6.54e-2)" "unprognostic (2.30e-2)" NIFK "hNIFK, MKI67IP, Nopp34" ENSG00000155438 "Nucleolar protein interacting with the FHA domain of MKI67" Q9BYG3 2 121726945-121736911 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 172.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 7725185.5;T-cells: 8282240.7" "Tissue enhanced" "Detected in many" "bone marrow: 438296.1" "CAB015382, HPA035735, HPA035736, CAB075728, CAB075729" Supported Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 190 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "CAB015382: , CAB075728: , CAB075729: , HPA035735: , HPA035736: " "unprognostic (3.00e-2)" "unprognostic (1.21e-1)" "unprognostic (4.17e-2)" "unprognostic (2.77e-2)" "unprognostic (3.83e-2)" "unprognostic (9.43e-2)" "unprognostic (3.70e-1)" "potential prognostic unfavorable (6.33e-5)" "unprognostic (5.68e-3)" "unprognostic (8.30e-3)" "unprognostic (4.05e-1)" "potential prognostic unfavorable (8.84e-5)" "potential prognostic unfavorable (1.52e-7)" "validated prognostic unfavorable (8.56e-5)" "validated prognostic unfavorable (8.39e-4)" "unprognostic (3.86e-2)" "unprognostic (4.52e-2)" "unprognostic (5.28e-2)" "unprognostic (7.52e-3)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (3.18e-2)" "unprognostic (3.75e-2)" "unprognostic (4.76e-2)" "unprognostic (3.29e-2)" "unprognostic (1.38e-1)" "unprognostic (1.64e-1)" "unprognostic (2.38e-1)" "unprognostic (7.14e-2)" "unprognostic (2.25e-1)" NIN ENSG00000100503 Ninein Q8N4C6 14 50719763-50831162 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 38.9" "Cell type enhanced" "Detected in many" "Müller glia: 339.6;Neutrophil progenitors: 451.7;Neutrophils: 1499.1" "Cell type enriched" "Detected in all" 4 "Neutrophils: 1499.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 24.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 635937.0;Macrophages: 660210.1;T-cells: 1250059.8" "Tissue enhanced" "Detected in some" "bone marrow: 8174506.5" "HPA005939, HPA070691" Approved Supported "Nucleoli,Nucleoli rim,Centrosome,Basal body" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 69 "Centrosome, Basal body" "Nucleoli, Nucleoli rim" "HPA005939: , HPA070691: " "unprognostic (1.50e-3)" "unprognostic (8.50e-2)" "unprognostic (2.87e-2)" "unprognostic (3.05e-2)" "unprognostic (4.74e-2)" "unprognostic (9.28e-2)" "unprognostic (6.15e-2)" "unprognostic (2.51e-3)" "unprognostic (6.05e-2)" "unprognostic (6.40e-3)" "potential prognostic favorable (1.93e-5)" "unprognostic (9.08e-3)" "unprognostic (2.32e-2)" "unprognostic (9.79e-2)" "unprognostic (2.10e-1)" "unprognostic (2.02e-2)" "unprognostic (1.29e-2)" "unprognostic (2.41e-1)" "unprognostic (1.80e-1)" "unprognostic (1.80e-3)" "unprognostic (1.32e-1)" "unprognostic (4.35e-2)" "unprognostic (2.26e-3)" "unprognostic (2.35e-1)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" "unprognostic (1.17e-3)" "unprognostic (3.34e-1)" "unprognostic (2.38e-1)" "unprognostic (2.65e-2)" "unprognostic (1.84e-1)" NIPBL "DKFZp434L1319, FLJ11203, FLJ12597, FLJ13354, FLJ13648, IDN3, Scc2" ENSG00000164190 "NIPBL cohesin loading factor" Q6KC79 5 36876769-37066413 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Activator, Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1263.5" "Cell type enhanced" "Detected in all" "Neutrophils: 1263.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "intestine: 6409107.4" "HPA040834, HPA058239" Approved Supported Nucleoplasm,Vesicles,Cytosol No No "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 37 Nucleoplasm "Vesicles, Cytosol" "HPA040834: , HPA058239: " "unprognostic (1.08e-1)" "unprognostic (4.46e-2)" "unprognostic (3.44e-1)" "unprognostic (1.99e-3)" "unprognostic (1.76e-1)" "unprognostic (3.26e-1)" "unprognostic (7.37e-2)" "unprognostic (1.18e-1)" "unprognostic (8.10e-2)" "unprognostic (8.94e-3)" "validated prognostic favorable (1.85e-5)" "validated prognostic favorable (1.67e-4)" "unprognostic (6.71e-2)" "unprognostic (2.03e-2)" "unprognostic (4.73e-1)" "unprognostic (3.20e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-1)" "unprognostic (1.82e-1)" "unprognostic (9.61e-2)" "unprognostic (2.05e-1)" "unprognostic (5.88e-3)" "unprognostic (1.51e-3)" "unprognostic (1.63e-1)" "unprognostic (7.27e-3)" "unprognostic (2.06e-1)" "unprognostic (4.99e-2)" "unprognostic (1.71e-1)" "unprognostic (3.03e-1)" "unprognostic (9.61e-3)" "unprognostic (1.80e-1)" NKPD1 FLJ33600 ENSG00000179846 "NTPase KAP family P-loop domain containing 1" Q17RQ9 19 45149744-45160982 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "skin 1: 11.2" "Cell type enhanced" "Detected in many" "Epicardial cells: 6.8;Epididymal basal cells: 5.3;Late primary spermatocytes: 7.7;Retinal ganglion cells: 7.7;Suprabasal keratinocytes: 4.4" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 6.8;Neuronal cells: 7.7;Spermatogenic cell types: 7.7" "Cell type enhanced" "Detected in many" "lower rhombic lip: 6.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary gland basal cells, Pituitary gland - Corticotropes, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 265 "Fallopian tube cells: 31123.1;Granulosa cells: 21854.6" "Not detected" "Not detected" HPA043339 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "HPA043339: " "unprognostic (1.49e-1)" "unprognostic (1.98e-1)" "unprognostic (5.68e-2)" "unprognostic (2.23e-1)" NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600655-42648735 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" "bone marrow: 1355563.4;lymphoid tissue: 483336.5" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 16 "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: , HPA051576: " "potential prognostic favorable (5.56e-5)" "unprognostic (7.25e-2)" "unprognostic (2.72e-1)" "unprognostic (8.63e-2)" "unprognostic (5.77e-2)" "unprognostic (1.14e-1)" "unprognostic (6.53e-3)" "unprognostic (3.31e-2)" "potential prognostic favorable (6.80e-4)" "unprognostic (1.02e-2)" "potential prognostic unfavorable (9.72e-4)" "unprognostic (1.18e-1)" "unprognostic (1.93e-2)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (2.67e-2)" "unprognostic (1.32e-1)" "unprognostic (4.49e-3)" "unprognostic (1.15e-1)" "potential prognostic favorable (3.52e-4)" "unprognostic (3.71e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-2)" "unprognostic (7.23e-3)" "unprognostic (1.11e-2)" "unprognostic (1.94e-2)" "unprognostic (7.83e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-1)" "unprognostic (2.93e-1)" "unprognostic (2.92e-2)" "unprognostic (2.93e-1)" NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 72.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 888.5;Cone photoreceptor cells: 931.6;Podocytes: 841.9;Retinal bipolar cells: 612.9;Retinal pigment epithelial cells: 989.0" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 888.5;Neuronal cells: 931.6;Pigment cells: 989.0;Renal nephron cells: 841.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 45 "basophil: 30.0" "Lineage enriched" "Detected in single" 45 "granulocytes: 30.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 218655.1" "Not detected" "Not detected" "HPA018192, HPA056511" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 18: Adrenal cortex cells - Steroidogensis" 32 Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: , HPA056511: " "unprognostic (8.81e-2)" "unprognostic (9.97e-3)" "unprognostic (1.01e-1)" "unprognostic (4.26e-2)" "unprognostic (2.02e-1)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" "unprognostic (1.01e-1)" "unprognostic (5.76e-2)" "unprognostic (2.88e-1)" "potential prognostic favorable (3.62e-4)" "unprognostic (8.83e-3)" "unprognostic (4.55e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (6.66e-2)" "unprognostic (4.56e-2)" "unprognostic (1.55e-2)" "unprognostic (3.93e-3)" "unprognostic (3.21e-3)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.60e-2)" "unprognostic (3.09e-3)" "unprognostic (5.94e-2)" "unprognostic (2.74e-2)" "unprognostic (1.21e-1)" "unprognostic (2.29e-1)" "unprognostic (4.82e-2)" "unprognostic (5.40e-2)" NLN "AGTBP, KIAA1226" ENSG00000123213 Neurolysin Q9BYT8 5 65722205-65871725 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.6;intermediate monocyte: 3.3;myeloid DC: 2.2;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 5 "dendritic cells: 2.2;monocytes: 3.3" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "liver: 22417212.5" HPA031862 Approved Approved Mitochondria Yes No 29000 "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Mitochondria "HPA031862: " "unprognostic (2.95e-1)" "unprognostic (4.45e-3)" "unprognostic (1.40e-1)" "unprognostic (5.41e-2)" "unprognostic (7.47e-2)" "unprognostic (7.05e-2)" "unprognostic (7.73e-2)" "unprognostic (4.53e-1)" "unprognostic (2.22e-2)" "unprognostic (6.74e-2)" "unprognostic (3.91e-3)" "unprognostic (1.75e-1)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (1.10e-2)" "unprognostic (2.41e-3)" "unprognostic (1.78e-2)" "unprognostic (8.12e-2)" "unprognostic (1.67e-1)" "unprognostic (4.23e-1)" "unprognostic (1.95e-2)" "unprognostic (1.55e-3)" "unprognostic (6.89e-3)" "unprognostic (3.30e-2)" "unprognostic (1.07e-1)" "unprognostic (1.01e-3)" "unprognostic (4.09e-2)" "unprognostic (1.16e-2)" "unprognostic (4.36e-2)" "unprognostic (4.82e-2)" "unprognostic (3.32e-2)" NLRC3 "CLR16.2, FLJ00348, NOD3" ENSG00000167984 "NLR family CARD domain containing 3" Q7RTR2 16 3539033-3577403 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 6.1;lymphoid tissue: 12.7" "Cell type enhanced" "Detected in many" "B-cells: 35.0;Cardiomyocytes: 96.9;Endometrial ciliated cells: 24.9;Epicardial cells: 61.4;Hematopoietic stem cells: 27.2;Innate lymphoid cells: 58.9;Megakaryocyte-Erythroid progenitors: 26.7;NK-cells: 107.6;Respiratory ciliated cells: 24.5;T-cells: 73.6;Thymocytes: 41.5" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 61.4;Innate lymphoid cells: 58.9;Myocytes: 96.9;NK-cells: 107.6;T-cells: 73.6" "Cell type enriched" "Detected in many" 9 "leukocyte: 91.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Leukemia: 10.5;lymphoma: 10.5" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Spleen - B-cells (Spleen), Stomach - T-cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" "B-cells: 3387740.7;T-cells: 3075459.1" "Tissue enriched" "Detected in single" 5753 "lymphoid tissue: 575334.0" HPA048062 Supported "Vesicles,Centriolar satellite,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 Cytosol "Vesicles, Centriolar satellite" "HPA048062: " "unprognostic (2.64e-2)" "unprognostic (1.29e-2)" "unprognostic (4.42e-3)" "unprognostic (2.03e-2)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "potential prognostic favorable (1.62e-4)" "unprognostic (4.14e-2)" "unprognostic (2.02e-1)" "potential prognostic favorable (9.36e-5)" "potential prognostic favorable (7.21e-4)" "unprognostic (3.94e-1)" "unprognostic (2.06e-1)" "unprognostic (6.70e-2)" "unprognostic (3.48e-3)" "unprognostic (2.00e-1)" "unprognostic (1.11e-1)" "unprognostic (3.46e-3)" "unprognostic (6.70e-2)" "unprognostic (1.50e-1)" NLRC4 "CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, ipaf" ENSG00000091106 "NLR family CARD domain containing 4" Q9NPP4 2 32224453-32265732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 8.5;lymphoid tissue: 11.3" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 139.4;Neutrophil progenitors: 320.1;Neutrophils: 348.1" "Group enriched" "Detected in many" 4 "Myocytes: 139.4;Neutrophils: 348.1" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 36.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 49.6;intermediate monocyte: 57.2;myeloid DC: 32.5;neutrophil: 24.7;non-classical monocyte: 46.7" "Group enriched" "Detected in many" 28 "dendritic cells: 32.5;granulocytes: 24.7;monocytes: 57.2" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Kidney - Macrophages, Prostate - Macrophages, Spleen - Neutrophils_2, Thyroid gland - Macrophages" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Neutrophils: 73083454.8" "Tissue enhanced" "Detected in some" "bone marrow: 11613739.4" "HPA006592, HPA075894" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 9 Cytosol "Vesicles, Plasma membrane" "HPA006592: , HPA075894: " "unprognostic (2.48e-1)" "unprognostic (7.11e-2)" "unprognostic (1.59e-1)" "unprognostic (8.65e-3)" "unprognostic (3.08e-1)" "unprognostic (4.52e-2)" "unprognostic (7.36e-2)" "unprognostic (3.42e-2)" "unprognostic (4.59e-1)" "unprognostic (1.90e-1)" "unprognostic (3.27e-1)" "unprognostic (3.63e-3)" "unprognostic (2.93e-2)" "unprognostic (6.75e-2)" "unprognostic (2.36e-1)" "unprognostic (5.37e-2)" "unprognostic (1.06e-1)" "unprognostic (1.95e-1)" "unprognostic (2.66e-2)" NME4 "NDPKD, nm23-H4, NM23H4" ENSG00000103202 "NME/NM23 nucleoside diphosphate kinase 4" O00746 16 396725-410367 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 204.5;Epididymal efferent duct absorptive cells: 193.6;Erythrocyte progenitors: 372.5;Hofbauer cells: 217.0;Megakaryocytes: 259.6;Smooth muscle cells: 255.4" "Cell type enhanced" "Detected in all" "Erythrocytes: 372.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 10533931.5" "Tissue enhanced" "Detected in some" "bone marrow: 3107795.0;ovary: 2734825.8" "CAB045997, HPA072588" Approved Supported Mitochondria Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 62 Mitochondria "CAB045997: , HPA072588: " "unprognostic (6.57e-2)" "unprognostic (2.60e-1)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (8.32e-4)" "unprognostic (1.90e-1)" "unprognostic (1.27e-1)" "unprognostic (1.59e-1)" "unprognostic (1.71e-1)" "unprognostic (1.94e-1)" "unprognostic (1.12e-2)" "validated prognostic unfavorable (6.14e-7)" "validated prognostic unfavorable (1.16e-7)" "unprognostic (9.05e-2)" "unprognostic (1.15e-2)" "unprognostic (6.25e-3)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (2.37e-2)" "unprognostic (3.81e-1)" "unprognostic (3.84e-2)" "unprognostic (1.81e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (4.79e-2)" "potential prognostic favorable (6.84e-4)" "unprognostic (1.23e-1)" "unprognostic (2.51e-1)" "unprognostic (2.49e-2)" "unprognostic (9.41e-2)" "unprognostic (1.56e-1)" "unprognostic (4.89e-3)" "unprognostic (1.81e-2)" NME5 "nm23-H5, RSPH23" ENSG00000112981 "NME/NM23 family member 5" P56597 5 138115175-138139443 "Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hydrolase" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 35.0;testis: 49.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 251.8;Early spermatids: 647.6;Endometrial ciliated cells: 219.1;Ependymal cells: 328.2;Epididymal efferent duct ciliated cells: 259.8;Fallopian tube ciliated cells: 333.0;Late primary spermatocytes: 1077.9;Late spermatids: 351.1;Respiratory ciliated cells: 408.3" "Group enriched" "Detected in many" 7 "Ciliated cells: 408.3;Spermatogenic cell types: 1077.9" "Cell type enhanced" "Detected in all" "ependymal cell: 357.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 3.8" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 167196 "Fallopian tube cells: 16719614.1" "Tissue enriched" "Detected in single" 65459 "fallopian tube: 6545939.2" "HPA044555, HPA058103" Enhanced Approved "Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 Cytosol "Plasma membrane, Primary cilium" "HPA044555: , HPA058103: " "unprognostic (4.36e-2)" "unprognostic (5.63e-2)" "unprognostic (9.69e-3)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (4.85e-2)" "potential prognostic favorable (4.85e-4)" "unprognostic (1.89e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (1.60e-1)" "unprognostic (5.58e-2)" "unprognostic (6.41e-2)" "unprognostic (3.53e-1)" "unprognostic (5.83e-2)" "unprognostic (2.15e-1)" "unprognostic (2.00e-2)" "unprognostic (3.43e-1)" "unprognostic (3.22e-1)" "unprognostic (1.17e-1)" "unprognostic (4.48e-2)" "unprognostic (1.06e-1)" "unprognostic (4.84e-2)" NME8 "CILD6, DNAI8, NM23-H8, SPTRX2, TXNDC3" ENSG00000086288 "NME/NM23 family member 8" Q8N427 7 37848597-37900397 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Hydrolase" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "bone marrow: 11.6;testis: 9.7" "Group enriched" "Detected in some" 6 "Early spermatids: 33.9;Late primary spermatocytes: 74.6;Late spermatids: 27.7" "Cell type enriched" "Detected in some" 10 "Spermatogenic cell types: 74.6" "Cell type enhanced" "Detected in single" "leukocyte: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.7" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in single" "Leukemia: 1.2" "Kidney - T-cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 10315 "heart muscle: 1031462.3" "CAB016416, HPA019259, HPA029572" Enhanced Supported "Nucleoplasm,Nuclear speckles,Primary cilium,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 30: White matter - Myelination" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Cytosol "Nucleoplasm, Nuclear speckles, Primary cilium" "CAB016416: , HPA019259: , HPA029572: " "unprognostic (2.37e-1)" NME9 "NM23-H9, TXL-2, TXNDC6" ENSG00000181322 "NME/NM23 family member 9" Q86XW9 3 138261437-138329886 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 19.5;fallopian tube: 16.5" "Cell type enhanced" "Detected in many" "Adipocytes: 97.4;Cardiomyocytes: 165.4;Choroid plexus epithelial cells: 170.9;Ependymal cells: 263.8;Epicardial cells: 109.2;Fallopian tube ciliated cells: 95.8;Myonuclei: 102.3;Oligodendrocyte progenitor cells: 159.3;Respiratory ciliated cells: 159.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 109.2;Ciliated cells: 263.8;Glial cells: 159.3;Myocytes: 165.4" "Cell type enhanced" "Detected in all" "ependymal cell: 279.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 92337 "Fallopian tube cells: 9233667.5" "Tissue enriched" "Detected in single" 132294 "fallopian tube: 13229403.7" "CAB020943, HPA040000, HPA043881" Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "Centriolar satellite" "CAB020943: , HPA040000: , HPA043881: " "unprognostic (4.61e-2)" "unprognostic (4.44e-2)" "unprognostic (1.71e-1)" "unprognostic (2.75e-2)" "unprognostic (1.03e-3)" "unprognostic (1.94e-2)" "unprognostic (2.21e-2)" "unprognostic (7.53e-2)" "unprognostic (3.02e-2)" "unprognostic (2.79e-2)" "unprognostic (1.90e-1)" "unprognostic (9.60e-2)" "unprognostic (5.46e-2)" "unprognostic (3.31e-2)" NMNAT2 "C1orf15, KIAA0479, PNAT2" ENSG00000157064 "Nicotinamide nucleotide adenylyltransferase 2" Q9BZQ4 1 183248237-183418380 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 79.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Brain excitatory neurons: 315.7;Brain inhibitory neurons: 314.2;Corticotrophs: 127.9;Gonadotrophs: 122.8;Lactotrophs: 266.6;Oligodendrocyte progenitor cells: 149.4;Other brain neurons: 253.6;Retinal amacrine cells: 175.9;Retinal ganglion cells: 312.9;Sertoli cells: 251.7;Somatotrophs: 205.6;Thyrotrophs: 261.1" "Cell type enhanced" "Detected in many" "Glial cells: 149.4;Neuronal cells: 315.7;Pituitary endocrine cells: 266.6;Reproductive supporting cells: 251.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 39.2;testis cancer: 23.1" "Breast - Endothelial cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 23849 "Neurons: 2384894.7" "Tissue enriched" "Detected in single" 71 "cerebral cortex: 7103.8" "HPA015708, HPA061714" Enhanced Supported Cytosol NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Cytosol "HPA015708: , HPA061714: " "unprognostic (2.59e-2)" "unprognostic (2.66e-1)" "unprognostic (4.97e-2)" "unprognostic (3.00e-2)" "unprognostic (7.05e-2)" "unprognostic (9.87e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.55e-3)" "unprognostic (8.48e-2)" "unprognostic (3.00e-3)" "potential prognostic unfavorable (8.48e-4)" "unprognostic (1.26e-1)" "unprognostic (2.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.82e-2)" "unprognostic (4.85e-2)" "potential prognostic favorable (3.67e-4)" "unprognostic (8.28e-3)" "unprognostic (3.66e-1)" "unprognostic (5.34e-2)" "unprognostic (1.41e-1)" NMRK1 "bA235O14.2, C9orf95, FLJ20559, NRK1" ENSG00000106733 "Nicotinamide riboside kinase 1" Q9NWW6 9 75060573-75088217 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 1132.6" "Cell type enriched" "Detected in all" 7 "Apical squamous epithelial cells: 1132.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 2158277.4" "Tissue enriched" "Detected in many" "skin: 6888743.5" HPA049795 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 11: T-cells - Unknown function" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 84: Apical squamous epithelium - Cornification" 3 "Nucleoplasm, Cytosol" Centrosome "HPA049795: " "unprognostic (8.44e-3)" "unprognostic (2.64e-2)" "unprognostic (7.19e-2)" "unprognostic (6.01e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (6.36e-2)" "unprognostic (1.76e-2)" "unprognostic (2.90e-2)" "potential prognostic favorable (9.23e-8)" "unprognostic (6.57e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (2.41e-2)" "unprognostic (1.12e-1)" "unprognostic (2.71e-2)" "unprognostic (6.02e-2)" "unprognostic (8.52e-2)" "unprognostic (1.39e-2)" "unprognostic (2.80e-1)" "unprognostic (2.24e-1)" "unprognostic (2.41e-1)" "unprognostic (1.74e-1)" "unprognostic (2.58e-1)" "unprognostic (1.31e-1)" "unprognostic (3.45e-1)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (3.19e-1)" "unprognostic (1.88e-2)" NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 44957992-45109016 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 424.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" NA NA 180000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 93: Hepatocytes - Bile production & excretion" 19 Cytosol "Plasma membrane" "HPA022949: , HPA022963: " "unprognostic (1.42e-1)" "unprognostic (4.72e-3)" "unprognostic (3.58e-1)" "unprognostic (2.16e-2)" "unprognostic (2.99e-2)" "unprognostic (2.60e-2)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (5.41e-4)" "unprognostic (1.09e-3)" "unprognostic (1.17e-1)" "unprognostic (8.36e-2)" "unprognostic (1.88e-2)" "unprognostic (1.49e-1)" "unprognostic (2.73e-2)" "unprognostic (1.54e-2)" "unprognostic (5.44e-2)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.10e-2)" "unprognostic (7.08e-2)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (1.23e-1)" "unprognostic (1.08e-3)" "unprognostic (2.70e-2)" "unprognostic (2.34e-1)" "unprognostic (6.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.07e-1)" "unprognostic (8.01e-2)" NNMT ENSG00000166741 "Nicotinamide N-methyltransferase" P40261 11 114257787-114313536 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 297.1" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 748.3;Endometrial secretory cells: 624.9;Fibroblasts: 759.4;Hepatocytes: 4376.1;Lymphatic endothelial cells: 435.4;Mesothelial cells: 554.7;Myosatellite cells: 1317.3" "Cell type enhanced" "Detected in many" "Hepatocytes: 4376.1;Stem cells: 1317.3" "Cell type enhanced" "Detected in many" "CGE interneuron: 27.7;endothelial cell: 37.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 89.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 59.6" "Colon - Neutrophils, Liver - Neutrophils, Skin - Macrophages, Testis - Endothelial cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in many" "Hepatocytes: 71071206.5" "Tissue enriched" "Detected in all" "liver: 92855584.1" HPA059180 Approved Approved "Golgi apparatus,Cytosol" NA NA 360000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 1 "Golgi apparatus" Cytosol "HPA059180: " "unprognostic (1.78e-1)" "unprognostic (1.83e-1)" "unprognostic (2.91e-1)" "unprognostic (2.43e-2)" "unprognostic (7.34e-2)" "unprognostic (2.33e-2)" "unprognostic (1.86e-1)" "unprognostic (3.01e-3)" "unprognostic (9.17e-3)" "unprognostic (3.38e-1)" "unprognostic (2.59e-2)" "unprognostic (5.59e-2)" "unprognostic (4.14e-1)" "unprognostic (5.68e-2)" "unprognostic (2.32e-3)" "unprognostic (6.90e-2)" "unprognostic (3.43e-1)" "unprognostic (7.25e-3)" "unprognostic (3.52e-2)" "unprognostic (2.26e-3)" "unprognostic (6.41e-3)" "unprognostic (3.09e-2)" "unprognostic (4.26e-1)" "unprognostic (5.29e-2)" "unprognostic (1.64e-1)" "unprognostic (2.52e-2)" "unprognostic (4.96e-2)" "potential prognostic unfavorable (4.23e-4)" "unprognostic (3.74e-2)" "unprognostic (1.02e-3)" "unprognostic (1.73e-1)" NNT ENSG00000112992 "Nicotinamide nucleotide transhydrogenase" Q13423 5 43602692-43707405 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Translocase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 223.6;tongue: 358.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 795.4;Choroid plexus epithelial cells: 278.3;Distal convoluted tubule cells: 275.7;Hepatocytes: 425.4;Myonuclei: 472.1;Parietal cells: 307.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 425.4;Myocytes: 795.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 105.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 2274318810.9" "Tissue enhanced" "Detected in all" "heart muscle: 893203680.5" "HPA004829, CAB004975, HPA066564" Enhanced Approved Mitochondria NA NA 120000 "Cluster 33: Non-specific - ATP binding" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 55: Myocytes - Oxidative muscle function" 11 Mitochondria "CAB004975: , HPA004829: , HPA066564: " "unprognostic (1.03e-1)" "unprognostic (2.96e-1)" "unprognostic (4.73e-1)" "unprognostic (2.25e-1)" "unprognostic (7.90e-2)" "unprognostic (1.49e-1)" "unprognostic (6.72e-2)" "unprognostic (5.32e-2)" "unprognostic (6.25e-2)" "potential prognostic unfavorable (1.57e-4)" "potential prognostic favorable (2.05e-10)" "unprognostic (2.31e-2)" "unprognostic (3.06e-3)" "unprognostic (2.82e-2)" "unprognostic (1.04e-3)" "unprognostic (1.82e-2)" "unprognostic (7.17e-2)" "unprognostic (1.41e-1)" "unprognostic (2.47e-2)" "unprognostic (1.04e-1)" "unprognostic (1.96e-1)" "unprognostic (1.16e-1)" "unprognostic (1.87e-1)" "unprognostic (2.01e-1)" "unprognostic (8.60e-3)" "unprognostic (1.97e-2)" "unprognostic (1.03e-1)" "unprognostic (6.48e-2)" "unprognostic (1.61e-1)" "unprognostic (1.49e-1)" "unprognostic (2.29e-1)" NOC2L "DKFZP564C186, NET15, NET7, NIR, PPP1R112" ENSG00000188976 "NOC2 like nucleolar associated transcriptional repressor" Q9Y3T9 1 944203-959309 "Essential proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" "fallopian tube: 2017752.2;intestine: 1826406.7;lymphoid tissue: 5099630.9;ovary: 5735172.1" "HPA044258, HPA062195" Approved Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 91000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 59 "Nucleoli, Nucleoli rim, Mitotic chromosome" "HPA044258: , HPA062195: " "unprognostic (1.07e-3)" "unprognostic (1.24e-1)" "unprognostic (1.54e-1)" "unprognostic (4.41e-2)" "unprognostic (1.80e-2)" "unprognostic (1.61e-1)" "unprognostic (9.16e-2)" "unprognostic (4.01e-3)" "unprognostic (2.60e-3)" "unprognostic (2.01e-2)" "potential prognostic favorable (5.32e-4)" "unprognostic (3.38e-1)" "unprognostic (1.10e-1)" "unprognostic (6.83e-3)" "potential prognostic unfavorable (5.01e-5)" "unprognostic (5.23e-2)" "unprognostic (4.87e-3)" "unprognostic (2.01e-1)" "unprognostic (2.16e-1)" "unprognostic (1.61e-1)" "unprognostic (6.84e-2)" "unprognostic (2.11e-1)" "unprognostic (2.14e-1)" "unprognostic (2.85e-1)" "unprognostic (1.11e-1)" "unprognostic (3.88e-3)" "unprognostic (4.46e-2)" "unprognostic (1.20e-1)" "unprognostic (8.53e-2)" "unprognostic (2.35e-2)" "unprognostic (2.44e-1)" NOC4L "MGC3162, NET49, Noc4, UTP19" ENSG00000184967 "Nucleolar complex associated 4 homolog" Q9BVI4 12 132144457-132152473 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 72.9;Late primary spermatocytes: 54.5;Late spermatids: 106.8;Oocytes: 73.7;Undifferentiated spermatogonia: 99.2" "Cell type enhanced" "Detected in many" "Oocytes: 73.7;Spermatogenic cell types: 106.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 2279195.1" "Group enriched" "Detected in many" "bone marrow: 475984.9;intestine: 645320.0;lymphoid tissue: 602825.1;salivary gland: 326573.5" HPA053424 Supported Nucleoplasm,Nucleoli No No "Cluster 13: Non-specific - Mitochondria" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 44 Nucleoli Nucleoplasm "HPA053424: " "unprognostic (1.27e-3)" "unprognostic (2.83e-2)" "unprognostic (1.01e-1)" "unprognostic (4.19e-2)" "unprognostic (3.82e-1)" "unprognostic (7.26e-2)" "unprognostic (7.10e-2)" "unprognostic (1.92e-2)" "unprognostic (5.41e-2)" "unprognostic (1.17e-1)" "unprognostic (1.90e-1)" "unprognostic (7.24e-2)" "unprognostic (5.73e-2)" "unprognostic (5.72e-3)" "unprognostic (1.18e-1)" "unprognostic (3.83e-3)" "unprognostic (2.35e-1)" "unprognostic (2.26e-1)" "unprognostic (2.60e-2)" "unprognostic (2.05e-1)" "unprognostic (2.46e-1)" "unprognostic (4.49e-2)" "unprognostic (1.69e-1)" "unprognostic (1.08e-1)" "unprognostic (8.24e-2)" "unprognostic (2.01e-1)" "unprognostic (2.09e-1)" "unprognostic (3.70e-2)" "unprognostic (5.76e-2)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" NOD2 "BLAU, CARD15, CD, CLR16.3, IBD1, NLRC2, PSORAS1" ENSG00000167207 "Nucleotide binding oligomerization domain containing 2" Q9HC29 16 50693588-50733077 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Autophagy, Immunity, Innate immunity" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.0;esophagus: 9.5;skin 1: 12.8;vagina: 10.2" "Cell type enhanced" "Detected in many" "cDC: 35.9;Endometrial luminal cells: 22.8;Esophageal apical cells: 57.1;Esophageal suprabasal cells: 42.0;Macrophages: 19.0;Monocyte progenitors: 28.1;monocytes: 61.3;Neutrophils: 58.2;Suprabasal keratinocytes: 29.6" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 57.1;dendritic cells: 35.9;Mononuclear phagocytes: 61.3;Neutrophils: 58.2;Suprabasal cells: 42.0" "Cell type enriched" "Detected in some" 4 "leukocyte: 15.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 4 "classical monocyte: 21.7;eosinophil: 5.6;intermediate monocyte: 12.2;myeloid DC: 20.4;neutrophil: 10.0;non-classical monocyte: 8.4" "Group enriched" "Detected in many" 9 "dendritic cells: 20.4;granulocytes: 10.0;monocytes: 21.7" "Cancer enhanced" "Detected in some" "lymphoma: 5.7" "Adipose visceral - Macrophages, Adrenal gland - Macrophages, Lung - NK-cells (Lung)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041985, HPA054494" Enhanced Supported "Golgi apparatus,Cytosol" No NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 69 "Golgi apparatus, Cytosol" "HPA041985: , HPA054494: " "unprognostic (5.48e-3)" "unprognostic (1.53e-1)" "unprognostic (2.59e-1)" "unprognostic (2.55e-1)" "unprognostic (1.79e-1)" "unprognostic (2.87e-1)" "unprognostic (3.42e-3)" "unprognostic (3.49e-1)" "unprognostic (6.89e-2)" "potential prognostic unfavorable (7.23e-4)" "unprognostic (1.09e-3)" "unprognostic (7.31e-3)" "unprognostic (8.10e-2)" "unprognostic (1.44e-2)" "unprognostic (1.86e-2)" "unprognostic (5.50e-2)" "unprognostic (1.66e-1)" "unprognostic (4.01e-2)" "unprognostic (7.01e-3)" "unprognostic (3.35e-3)" "unprognostic (5.06e-2)" "unprognostic (4.19e-2)" "unprognostic (1.53e-1)" "unprognostic (2.81e-3)" "unprognostic (1.09e-3)" "unprognostic (2.55e-1)" NOL12 "MGC3731, Nop25, RRP17" ENSG00000273899 "Nucleolar protein 12" Q9UGY1 22 37681673-37693476 "Essential proteins, Predicted intracellular proteins" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 14.9;Brain inhibitory neurons: 13.6;Colonocytes: 17.3;Early spermatids: 50.2;Enteric transient amplifying cells: 14.5;Enterocytes: 15.6;Goblet cells: 13.9;Late primary spermatocytes: 35.7;Late spermatids: 14.9" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 50.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 747047.7;T-cells: 780749.9" "Tissue enriched" "Detected in some" "lymphoid tissue: 290050.6" HPA003547 Uncertain Approved "Nucleoplasm,Nucleoli,Mitotic chromosome,Vesicles" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 15: Non-specific - Protein processing" 42 "Nucleoli, Mitotic chromosome" "Nucleoplasm, Vesicles" "HPA003547: " "unprognostic (5.26e-2)" "unprognostic (1.30e-1)" "unprognostic (1.57e-1)" "unprognostic (2.10e-2)" "unprognostic (2.82e-2)" "unprognostic (1.21e-1)" "unprognostic (3.14e-1)" "unprognostic (2.10e-1)" "unprognostic (1.41e-3)" "unprognostic (8.57e-3)" "unprognostic (1.67e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (2.22e-5)" "unprognostic (6.16e-2)" "unprognostic (2.29e-1)" "unprognostic (1.31e-3)" "unprognostic (1.16e-2)" "unprognostic (1.15e-2)" "unprognostic (1.22e-2)" "unprognostic (6.08e-3)" "unprognostic (2.72e-1)" "unprognostic (9.51e-2)" "unprognostic (8.67e-3)" "unprognostic (2.09e-1)" "unprognostic (3.68e-2)" "unprognostic (3.40e-3)" "unprognostic (6.63e-2)" "unprognostic (2.12e-1)" NOL3 "ARC, CARD2, MYP, NOP30" ENSG00000140939 "Nucleolar protein 3" O60936 16 67170154-67175737 "Disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 329.0;Esophageal suprabasal cells: 108.6;Myonuclei: 115.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 329.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 3.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Skeletal myofibers: 51857821.7" "Group enriched" "Detected in all" "heart muscle: 66742454.6;skeletal muscle: 70258600.5" CAB009208 Enhanced Supported Nucleoplasm,Cytosol NA NA 9700 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 45: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 62: Smooth muscle cells - Muscle contraction" 9 "Nucleoplasm, Cytosol" "CAB009208: " "unprognostic (2.66e-1)" "potential prognostic unfavorable (9.43e-4)" "unprognostic (7.96e-2)" "unprognostic (8.56e-3)" "unprognostic (1.26e-2)" "unprognostic (1.09e-1)" "validated prognostic unfavorable (8.58e-5)" "validated prognostic unfavorable (5.09e-4)" "unprognostic (6.14e-2)" "unprognostic (5.44e-2)" "unprognostic (5.71e-2)" "unprognostic (4.48e-1)" "unprognostic (2.07e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (8.86e-2)" "unprognostic (1.88e-1)" "unprognostic (2.47e-1)" "unprognostic (2.04e-2)" "unprognostic (2.09e-1)" "unprognostic (1.22e-1)" "unprognostic (4.52e-2)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (1.27e-2)" "unprognostic (8.52e-2)" "unprognostic (6.15e-2)" "unprognostic (1.03e-2)" "unprognostic (6.14e-3)" "unprognostic (3.80e-1)" "unprognostic (9.57e-2)" "unprognostic (1.42e-2)" NOL4 "CT125, HRIHFB2255, NOLP" ENSG00000101746 "Nucleolar protein 4" O94818 18 33851100-34224952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.6;pituitary gland: 6.3;retina: 5.8;testis: 11.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Bergmann glia: 210.9;Brain excitatory neurons: 225.4;Brain inhibitory neurons: 256.0;Corticotrophs: 1001.4;Early spermatids: 389.7;Gonadotrophs: 252.9;Lactotrophs: 567.9;Late primary spermatocytes: 279.7;Oligodendrocyte progenitor cells: 454.9;Other brain neurons: 250.5;Pancreatic islet cells: 397.4;Somatotrophs: 523.0;Thyrotrophs: 493.2" "Cell type enhanced" "Detected in many" "Glial cells: 454.9;Neuronal cells: 256.0;Pancreatic islet cells: 397.4;Pituitary endocrine cells: 1001.4;Spermatogenic cell types: 389.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 4.2;Kidney Renal Papillary Cell Carcinoma (TCGA): 2.4;Pancreatic Adenocarcinoma (TCGA): 1.9;Prostate Adenocarcinoma (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 8.6;Neuroblastoma: 7.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Liver - Hepatocytes, Minor Salivary Gland - Smooth muscle cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 7980973.3" "Group enriched" "Detected in some" 3725 "cerebral cortex: 456785.9;intestine: 288161.4" HPA046740 Supported Nucleoplasm No NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 5 Nucleoplasm "HPA046740: " "unprognostic (7.93e-2)" "unprognostic (3.52e-1)" "potential prognostic favorable (1.77e-4)" "unprognostic (1.59e-2)" "unprognostic (2.42e-2)" "unprognostic (1.16e-2)" "unprognostic (1.69e-2)" "unprognostic (7.41e-2)" NOL7 "C6orf90, dJ223E5.2, NOP27, PQBP3, RARG-1" ENSG00000225921 "Nucleolar protein 7" Q9UMY1 6 13615335-13632739 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 10797 "fallopian tube: 692058.6;lymphoid tissue: 698420.9;ovary: 1848696.5" HPA029185 Supported Supported "Nucleoli,Mitotic chromosome,Mitochondria" Yes Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 20 "Nucleoli, Mitotic chromosome" Mitochondria "HPA029185: " "unprognostic (2.46e-1)" "unprognostic (5.62e-2)" "unprognostic (1.34e-1)" "unprognostic (5.98e-2)" "unprognostic (1.12e-1)" "unprognostic (1.56e-1)" "unprognostic (1.43e-1)" "unprognostic (4.28e-2)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (2.09e-4)" "validated prognostic favorable (7.78e-6)" "validated prognostic favorable (6.90e-5)" "unprognostic (7.90e-3)" "unprognostic (2.76e-3)" "potential prognostic unfavorable (1.60e-6)" "unprognostic (2.66e-1)" "unprognostic (6.46e-2)" "unprognostic (3.24e-1)" "unprognostic (2.35e-3)" "potential prognostic favorable (1.22e-5)" "unprognostic (4.11e-2)" "unprognostic (1.51e-1)" "unprognostic (1.14e-1)" "unprognostic (2.96e-2)" "unprognostic (8.64e-3)" "unprognostic (2.15e-1)" "unprognostic (3.03e-1)" "unprognostic (2.42e-1)" "unprognostic (1.51e-1)" "unprognostic (2.23e-1)" "unprognostic (1.39e-1)" NOL8 "C9orf34, FLJ20736, Nop132" ENSG00000198000 "Nucleolar protein 8" Q76FK4 9 92297358-92325636 "Essential proteins, Predicted intracellular proteins" "rRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocyte-Erythroid progenitors: 113.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1447780.9;Neurons: 1959253.1" "Tissue enriched" "Detected in single" 133208 "lymphoid tissue: 13320840.5" "HPA044440, HPA062922" Uncertain Supported "Nucleoli,Mitotic chromosome" Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 9 Nucleoli "Mitotic chromosome" "HPA044440: , HPA062922: " "unprognostic (5.31e-2)" "unprognostic (5.26e-2)" "unprognostic (2.64e-2)" "unprognostic (1.60e-1)" "unprognostic (4.23e-1)" "unprognostic (3.27e-1)" "unprognostic (2.36e-1)" "unprognostic (7.77e-2)" "unprognostic (4.30e-2)" "unprognostic (6.66e-3)" "potential prognostic favorable (5.33e-6)" "unprognostic (5.09e-2)" "unprognostic (1.06e-1)" "unprognostic (7.89e-2)" "unprognostic (2.19e-1)" "unprognostic (8.96e-2)" "unprognostic (5.36e-3)" "unprognostic (6.97e-2)" "unprognostic (2.89e-1)" "unprognostic (1.66e-1)" "unprognostic (8.22e-2)" "unprognostic (1.17e-1)" "unprognostic (4.67e-2)" "unprognostic (5.32e-3)" "unprognostic (2.74e-2)" "unprognostic (1.69e-1)" "unprognostic (2.98e-2)" "unprognostic (3.07e-1)" "unprognostic (7.61e-2)" "unprognostic (1.31e-1)" "unprognostic (4.77e-2)" NOL9 "FLJ23323, Grc3, NET6" ENSG00000162408 "Nucleolar protein 9" Q5SY16 1 6521347-6554513 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "rRNA processing" "Kinase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 11174003.8" "Group enriched" "Detected in many" "lung: 1630197.9;pancreas: 790945.8" HPA036347 Supported "Nucleoli,Intermediate filaments" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 39 Nucleoli "Intermediate filaments" "HPA036347: " "unprognostic (8.97e-2)" "unprognostic (5.13e-2)" "unprognostic (7.81e-2)" "unprognostic (4.14e-2)" "unprognostic (8.43e-2)" "unprognostic (1.74e-1)" "unprognostic (2.88e-1)" "unprognostic (1.37e-3)" "unprognostic (2.09e-1)" "unprognostic (4.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.88e-3)" "unprognostic (4.25e-3)" "potential prognostic unfavorable (4.09e-8)" "unprognostic (2.06e-3)" "unprognostic (2.11e-1)" "unprognostic (5.39e-2)" "unprognostic (5.98e-2)" "potential prognostic favorable (6.81e-4)" "unprognostic (1.06e-1)" "unprognostic (4.36e-2)" "unprognostic (3.98e-3)" "unprognostic (8.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "potential prognostic favorable (9.63e-4)" "unprognostic (1.07e-1)" "unprognostic (1.44e-2)" "unprognostic (3.03e-1)" "unprognostic (5.85e-2)" "unprognostic (2.00e-1)" NONO "NMT55, NRB54, P54, P54NRB, PPP1R114" ENSG00000147140 "Non-POU domain containing octamer binding" Q15233 X 71254814-71301522 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, DNA damage, DNA recombination, DNA repair, Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor, RNA-binding" "Cancer-related genes, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB022069, HPA054094, HPA054559" Enhanced Enhanced "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA 4300000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 98 Nucleoplasm "Nucleoli, Nucleoli fibrillar center" "CAB022069: , HPA054094: , HPA054559: " "unprognostic (8.33e-2)" "unprognostic (3.48e-3)" "unprognostic (1.90e-1)" "unprognostic (1.08e-2)" "unprognostic (1.34e-1)" "unprognostic (1.56e-1)" "unprognostic (1.41e-1)" "unprognostic (2.67e-3)" "unprognostic (3.82e-2)" "potential prognostic unfavorable (1.15e-4)" "validated prognostic favorable (1.18e-5)" "validated prognostic favorable (7.31e-4)" "potential prognostic unfavorable (1.95e-4)" "validated prognostic unfavorable (3.83e-4)" "validated prognostic unfavorable (2.73e-6)" "unprognostic (9.95e-2)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (5.37e-2)" "unprognostic (5.87e-2)" "unprognostic (3.68e-1)" "unprognostic (7.54e-2)" "unprognostic (2.44e-2)" "unprognostic (1.92e-1)" "unprognostic (5.42e-2)" "unprognostic (3.01e-2)" "unprognostic (8.74e-2)" "unprognostic (9.44e-2)" "unprognostic (1.62e-1)" "unprognostic (1.62e-1)" "unprognostic (1.46e-1)" "unprognostic (2.30e-1)" NOP2 "NOL1, NOP120, NSUN1, p120" ENSG00000111641 "NOP2 nucleolar protein" P46087 12 6556863-6568691 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 10.3;Bergmann glia: 8.7;Brain excitatory neurons: 10.0;Brain inhibitory neurons: 10.6;Choroid plexus epithelial cells: 7.9;Enteric stem cells: 7.0;Ependymal cells: 6.8;Epididymal basal cells: 7.1;Microglia: 13.0;Oligodendrocyte progenitor cells: 6.9;Oligodendrocytes: 7.6;Other brain neurons: 9.7" "Cell type enhanced" "Detected in many" "Glial cells: 13.0;Neuronal cells: 10.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 56172948.3;T-cells: 65114369.4" "Tissue enriched" "Detected in many" "intestine: 54915882.3" HPA040119 Supported Enhanced Nucleoli No No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 98: Neurons - Neurotransmission & signaling" 78 Nucleoli "HPA040119: " "unprognostic (4.02e-2)" "unprognostic (1.57e-1)" "unprognostic (2.28e-1)" "unprognostic (8.53e-3)" "unprognostic (1.18e-1)" "unprognostic (9.89e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (5.16e-4)" "unprognostic (6.17e-2)" "unprognostic (1.83e-3)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (2.02e-3)" "unprognostic (4.30e-3)" "potential prognostic unfavorable (1.62e-6)" "unprognostic (5.55e-3)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (7.47e-3)" "unprognostic (6.23e-2)" "unprognostic (3.04e-1)" "unprognostic (2.47e-2)" "unprognostic (7.15e-3)" "unprognostic (4.20e-2)" "unprognostic (2.41e-2)" "unprognostic (1.03e-1)" "unprognostic (3.46e-3)" "unprognostic (7.41e-2)" "unprognostic (4.47e-2)" "unprognostic (8.79e-3)" "unprognostic (3.03e-1)" "unprognostic (1.28e-1)" "unprognostic (3.02e-1)" NOP53 "GLTSCR2, PICT-1, PICT1" ENSG00000105373 "NOP53 ribosome biogenesis factor" Q9NZM5 19 47745546-47757058 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ovarian stromal cells: 962.8;Pancreatic acinar cells: 1100.5" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "leukocyte: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "B-cells: 313.6;NK-cells: 97.4;T-cells: 245.6" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 1116548.7" "Tissue enriched" "Detected in single" 452 "lymphoid tissue: 45159.9" "HPA018999, HPA049600" Approved Supported Nucleoli NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 47: Endothelial cells - Vasculature" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 103 Nucleoli "HPA018999: , HPA049600: " "potential prognostic favorable (9.32e-4)" "unprognostic (1.27e-3)" "unprognostic (2.49e-1)" "unprognostic (2.60e-2)" "unprognostic (6.66e-2)" "unprognostic (4.89e-2)" "unprognostic (1.88e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (2.42e-2)" "potential prognostic favorable (4.94e-5)" "unprognostic (2.37e-1)" "unprognostic (1.77e-1)" "unprognostic (2.11e-1)" "unprognostic (9.72e-2)" "unprognostic (4.08e-3)" "unprognostic (1.57e-1)" "unprognostic (5.71e-2)" "unprognostic (1.12e-1)" "unprognostic (3.30e-3)" "unprognostic (1.00e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-1)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (6.32e-2)" "unprognostic (1.22e-1)" "unprognostic (1.82e-1)" "unprognostic (4.30e-2)" NOP9 C14orf21 ENSG00000196943 "NOP9 nucleolar protein" Q86U38 14 24299850-24309124 "Essential proteins, Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cholangiocytes: 3.9;Early spermatids: 2.7;Esophageal apical cells: 2.5;Retinal pigment epithelial cells: 4.3" "Cell type enhanced" "Detected in many" "Pigment cells: 4.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "intestine: 8745155.0;ovary: 7577847.3" HPA000850 Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 13 Nucleoplasm "Nucleoli, Cytosol" "HPA000850: " "unprognostic (2.61e-1)" "unprognostic (9.19e-2)" "unprognostic (4.15e-3)" "unprognostic (2.39e-2)" "unprognostic (3.75e-2)" "unprognostic (1.18e-1)" "unprognostic (2.64e-3)" "unprognostic (1.82e-1)" "unprognostic (1.86e-3)" "validated prognostic favorable (2.99e-6)" "validated prognostic favorable (2.12e-4)" "unprognostic (7.95e-3)" "unprognostic (2.46e-2)" "unprognostic (3.20e-1)" "unprognostic (8.32e-3)" "unprognostic (9.66e-2)" "unprognostic (6.66e-2)" "unprognostic (7.62e-3)" "unprognostic (4.72e-1)" "unprognostic (2.00e-1)" "unprognostic (5.17e-2)" "unprognostic (1.23e-2)" "unprognostic (4.69e-2)" "unprognostic (9.63e-2)" "unprognostic (2.83e-1)" "unprognostic (2.04e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (1.35e-1)" NOTUM ENSG00000185269 "Notum, palmitoleoyl-protein carboxylesterase" Q6P988 17 81952507-81961840 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "placenta: 127.5" "Cell type enriched" "Detected in some" 44 "Extravillous trophoblasts: 1955.2" "Cell type enriched" "Detected in many" 44 "Trophoblast cells: 1955.2" "Cell type enhanced" "Detected in many" "astrocyte: 8.1;endothelial cell: 13.1" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 113.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gastric cancer: 49.8" "Breast - Breast glandular cells (progenitors), Heart muscle - Cardiomyocytes, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2757 "intestine: 275707.8" HPA022851 Approved "Endoplasmic reticulum" "Secreted in female reproductive system" Enzyme NA NA 2000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 1 "Endoplasmic reticulum" "HPA022851: " "unprognostic (3.31e-2)" "unprognostic (9.11e-2)" "unprognostic (1.67e-1)" "unprognostic (4.21e-3)" "unprognostic (1.60e-1)" "unprognostic (6.02e-3)" "unprognostic (2.48e-2)" "unprognostic (1.10e-2)" "unprognostic (5.02e-3)" "unprognostic (3.47e-2)" "unprognostic (3.70e-1)" "unprognostic (7.54e-2)" "unprognostic (1.22e-1)" "unprognostic (4.94e-2)" "unprognostic (2.19e-1)" "unprognostic (1.60e-1)" "unprognostic (9.88e-2)" "unprognostic (7.82e-2)" "unprognostic (5.56e-3)" "unprognostic (9.15e-2)" "unprognostic (1.82e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (4.45e-4)" NOVA2 "ANOVA, NOVA-2, NOVA3" ENSG00000104967 "NOVA alternative splicing regulator 2" Q9UNW9 19 45933734-45974044 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Autism spectrum disorder, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.3" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 39.1;Brain inhibitory neurons: 47.6;Corticotrophs: 29.1;Lactotrophs: 23.8;Lymphatic endothelial cells: 54.0;Oligodendrocyte progenitor cells: 29.2;Oligodendrocytes: 20.0;Other brain neurons: 38.3;Retinal amacrine cells: 46.1;Retinal bipolar cells: 80.4;Vascular endothelial cells: 68.9" "Group enriched" "Detected in many" 4 "Endothelial cells: 68.9;Glial cells: 29.2;Neuronal cells: 80.4;Pituitary endocrine cells: 29.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Neuroblastoma: 11.5" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 64346590.5" "Tissue enhanced" "Detected in some" "cerebral cortex: 3361990.7;lung: 4601161.2" HPA045607 Enhanced Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus" No No "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" "Golgi apparatus" "Nucleoplasm, Nuclear bodies" "HPA045607: " "unprognostic (1.33e-1)" "unprognostic (2.57e-2)" "unprognostic (1.20e-1)" "unprognostic (2.23e-2)" "unprognostic (3.15e-1)" "unprognostic (2.13e-1)" "unprognostic (2.27e-3)" "validated prognostic favorable (1.18e-5)" "validated prognostic favorable (5.48e-5)" "unprognostic (2.48e-3)" "unprognostic (1.18e-1)" "unprognostic (8.36e-2)" "unprognostic (1.84e-2)" "unprognostic (1.46e-3)" "unprognostic (8.26e-3)" "unprognostic (1.55e-2)" "unprognostic (3.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.14e-1)" "unprognostic (1.47e-1)" "unprognostic (7.05e-3)" NOXRED1 "C14orf148, FLJ32809" ENSG00000165555 "NADP dependent oxidoreductase domain containing 1" Q6NXP6 14 77394021-77423523 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "retina: 4.0;testis: 5.7" "Group enriched" "Detected in many" 4 "Early spermatids: 152.5;Late primary spermatocytes: 76.9;Late spermatids: 182.0" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 182.0" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055658, HPA060408" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 47: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Vesicles "Plasma membrane" "HPA055658: , HPA060408: " "unprognostic (2.51e-1)" NPEPPS "MP100, PSA" ENSG00000141279 "Aminopeptidase puromycin sensitive" P55786 17 47522942-47624665 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1612.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1612.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 659558849.6" "Low tissue specificity" "Detected in all" "HPA021453, HPA045649" Uncertain Supported Cytosol No No 4300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 12 Cytosol "HPA021453: , HPA045649: " "unprognostic (2.51e-2)" "unprognostic (2.16e-1)" "unprognostic (4.68e-2)" "unprognostic (6.69e-3)" "potential prognostic favorable (3.84e-4)" "unprognostic (1.75e-1)" "unprognostic (3.12e-1)" "unprognostic (1.64e-1)" "unprognostic (6.43e-2)" "potential prognostic unfavorable (2.99e-6)" "potential prognostic favorable (1.45e-5)" "unprognostic (1.07e-2)" "unprognostic (1.61e-2)" "potential prognostic unfavorable (7.82e-5)" "unprognostic (4.06e-3)" "unprognostic (2.80e-2)" "unprognostic (2.66e-3)" "unprognostic (3.62e-2)" "unprognostic (3.80e-1)" "unprognostic (4.76e-2)" "unprognostic (5.44e-3)" "unprognostic (5.80e-3)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (4.10e-2)" "unprognostic (1.88e-2)" "unprognostic (4.07e-1)" "unprognostic (1.57e-1)" "unprognostic (6.63e-2)" "unprognostic (4.43e-2)" "unprognostic (8.64e-3)" "unprognostic (1.64e-1)" NPHP4 "KIAA0673, POC10, SLSN4" ENSG00000131697 "Nephrocystin 4" O75161 1 5862811-5992473 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 84.2;Ependymal cells: 85.4;Gonadotrophs: 100.2;Lactotrophs: 90.6;Somatotrophs: 79.0" "Cell type enhanced" "Detected in all" "Ciliated cells: 85.4;Pituitary endocrine cells: 100.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 26396616.7" "Tissue enriched" "Detected in single" 131587 "fallopian tube: 13158693.7" "HPA063852, HPA065526" Approved Approved "Nucleoplasm,Nuclear bodies,Vesicles,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 23 Nucleoplasm "Nuclear bodies, Vesicles, Cytosol" "HPA063852: , HPA065526: " "unprognostic (7.14e-3)" "unprognostic (5.67e-2)" "unprognostic (2.42e-1)" "unprognostic (3.29e-2)" "unprognostic (4.86e-2)" "unprognostic (1.75e-1)" "unprognostic (1.51e-1)" "unprognostic (2.89e-3)" "unprognostic (1.56e-2)" "potential prognostic favorable (3.10e-5)" "unprognostic (1.05e-1)" "unprognostic (1.28e-2)" "unprognostic (1.05e-2)" "unprognostic (2.51e-1)" "unprognostic (3.51e-2)" "unprognostic (9.62e-3)" "unprognostic (2.21e-1)" "unprognostic (1.79e-2)" "potential prognostic favorable (7.98e-4)" "unprognostic (1.85e-1)" "unprognostic (1.08e-2)" "unprognostic (3.77e-1)" "unprognostic (1.69e-1)" "unprognostic (2.48e-3)" "unprognostic (2.66e-2)" "unprognostic (6.11e-2)" "unprognostic (3.38e-1)" "unprognostic (1.11e-1)" "unprognostic (7.59e-2)" NPM1 "B23, NPM" ENSG00000181163 "Nucleophosmin 1" P06748 5 171387116-171411810 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, RNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Migrating cytotrophoblasts: 1912.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA011384, CAB012983" Supported Enhanced "Nucleoplasm,Nucleoli rim" NA Yes 2300000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 697 "Nucleoli rim" Nucleoplasm "CAB012983: , HPA011384: " "unprognostic (3.50e-3)" "unprognostic (1.99e-2)" "unprognostic (1.10e-1)" "unprognostic (6.30e-2)" "unprognostic (1.38e-1)" "unprognostic (2.19e-1)" "unprognostic (1.41e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (3.04e-2)" "potential prognostic favorable (1.58e-6)" "unprognostic (3.38e-2)" "unprognostic (1.14e-3)" "validated prognostic unfavorable (2.17e-6)" "validated prognostic unfavorable (3.24e-5)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (5.97e-3)" "unprognostic (1.89e-1)" "unprognostic (3.85e-1)" "unprognostic (4.79e-2)" "unprognostic (7.50e-3)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (6.99e-2)" "unprognostic (4.56e-2)" "unprognostic (5.33e-3)" "unprognostic (3.28e-1)" "unprognostic (4.40e-2)" "unprognostic (3.04e-1)" "unprognostic (4.15e-1)" "unprognostic (5.82e-2)" "unprognostic (5.17e-2)" NPM2 ENSG00000158806 "Nucleophosmin/nucleoplasmin 2" Q86SE8 8 22024125-22036897 "Predicted intracellular proteins" Fertilization "Chaperone, Chromatin regulator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 62.0;parathyroid gland: 36.9" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 31.2;Brain inhibitory neurons: 28.5;Cone photoreceptor cells: 29.0;Epididymal clear cells: 30.6;Late spermatids: 24.8;Oocytes: 59.9;Other brain neurons: 34.1;Pancreatic islet cells: 25.5;Retinal amacrine cells: 47.5;Retinal ganglion cells: 46.4" "Cell type enhanced" "Detected in many" "Neuronal cells: 47.5;Oocytes: 59.9" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 28.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "eosinophil: 1.5" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Oocytes: 7092823.5" "Tissue enhanced" "Detected in many" "lymphoid tissue: 1731167.0" HPA041070 Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 9 "Nucleoplasm, Nucleoli" "HPA041070: " "unprognostic (3.05e-2)" "unprognostic (1.53e-1)" "unprognostic (4.61e-2)" "unprognostic (1.59e-2)" "unprognostic (3.54e-2)" "unprognostic (2.37e-1)" "unprognostic (1.82e-2)" "potential prognostic favorable (5.56e-4)" "unprognostic (2.04e-1)" "unprognostic (3.86e-2)" "unprognostic (9.26e-3)" "unprognostic (2.96e-2)" "unprognostic (2.67e-3)" "unprognostic (2.56e-1)" "unprognostic (1.89e-1)" "unprognostic (1.69e-1)" "unprognostic (7.72e-2)" "unprognostic (4.91e-2)" "unprognostic (1.95e-1)" "unprognostic (1.61e-1)" "unprognostic (2.22e-1)" "unprognostic (1.26e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (4.43e-1)" "unprognostic (5.14e-3)" "unprognostic (2.70e-2)" "unprognostic (2.22e-3)" "unprognostic (1.61e-1)" "unprognostic (1.15e-1)" "unprognostic (8.86e-2)" "unprognostic (5.39e-2)" NQO1 "DHQU, DIA4, DTD, NMOR1, QR1" ENSG00000181019 "NAD(P)H quinone dehydrogenase 1" P15559 16 69706996-69726668 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 493.1" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 466.0;Esophageal basal cells: 347.8;Esophageal suprabasal cells: 343.2;Foveolar cells: 711.0;Gastric progenitor cells: 880.5;Ocular epithelial cells: 1049.3;Parietal cells: 367.7;Respiratory ciliated cells: 328.2;Salivary duct cells: 558.0;Suprabasal keratinocytes: 255.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 1049.3;Ductal cells: 558.0;Gastric glandular cells: 711.0;Proliferating cells: 880.5" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Distal tubules: 14211355.5;Glomeruli: 53507965.2;Large ducts: 50659839.2" "Tissue enhanced" "Detected in many" "intestine: 11108310.3" "HPA007308, CAB012421" Enhanced Enhanced Cytosol NA NA 100000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 12 Cytosol "CAB012421: , HPA007308: " "unprognostic (3.56e-3)" "unprognostic (4.07e-3)" "unprognostic (8.12e-2)" "unprognostic (1.07e-2)" "unprognostic (2.64e-1)" "unprognostic (1.70e-1)" "unprognostic (7.46e-3)" "unprognostic (1.38e-2)" "unprognostic (1.12e-3)" "unprognostic (3.77e-1)" "unprognostic (2.06e-2)" "unprognostic (1.70e-2)" "potential prognostic unfavorable (8.44e-5)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (5.50e-3)" "unprognostic (8.62e-2)" "unprognostic (2.20e-1)" "unprognostic (9.53e-2)" "unprognostic (3.07e-1)" "unprognostic (1.24e-1)" "unprognostic (2.41e-1)" "unprognostic (1.03e-2)" "unprognostic (4.69e-2)" "unprognostic (6.81e-2)" "unprognostic (6.48e-2)" "unprognostic (1.59e-2)" "unprognostic (5.35e-2)" "unprognostic (1.27e-1)" "unprognostic (2.35e-1)" "unprognostic (1.47e-1)" "unprognostic (3.46e-2)" NR0B1 "AHC, AHCH, DAX1, DSS" ENSG00000169297 "Nuclear receptor subfamily 0 group B member 1" P51843 X 30304206-30309390 "Cancer-related genes, Disease related genes, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Receptor, Repressor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 34.7;testis: 19.7" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 58.8;Adrenal medulla cells: 10.6;Corticotrophs: 6.8;Epididymal efferent duct ciliated cells: 12.2;Gonadotrophs: 21.7;Oligodendrocyte progenitor cells: 18.8;Pancreatic islet cells: 20.7;Sertoli cells: 47.5" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 58.8;Glial cells: 18.8;Pancreatic islet cells: 20.7;Pituitary endocrine cells: 21.7;Reproductive supporting cells: 47.5" "Group enriched" "Detected in some" 35 "committed oligodendrocyte precursor: 7.2;oligodendrocyte precursor cell: 21.5" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 11.6" "Region enriched" "Detected in many" 7 "hypothalamus: 10.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 57.1" "Adrenal gland - Adrenal cortex cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Sertoli cells" "Not detected" "Not detected" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Cell type enriched" "Detected in single" 37 "Pancreatic islets: 3727.1" "Not detected" "Not detected" "HPA061948, HPA067207" Supported "Nuclear speckles,Vesicles,Centriolar satellite" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 7: Liver cancer - Metabolism" "Cluster 18: Adrenal cortex cells - Steroidogensis" 20 "Nuclear speckles" "Vesicles, Centriolar satellite" "HPA061948: , HPA067207: " "unprognostic (3.24e-1)" "unprognostic (1.12e-1)" "unprognostic (4.65e-2)" "potential prognostic favorable (1.25e-4)" "unprognostic (3.32e-2)" "unprognostic (4.96e-2)" "unprognostic (1.51e-2)" "unprognostic (2.59e-1)" "unprognostic (6.16e-2)" "unprognostic (1.07e-1)" "unprognostic (8.96e-3)" "unprognostic (5.37e-2)" "unprognostic (1.91e-3)" NR1D1 "ear-1, hRev, Rev-ErbAalpha, REVERBA, REVERBalpha, THRA1, THRAL" ENSG00000126368 "Nuclear receptor subfamily 1 group D member 1" P20393 17 40092793-40100589 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 329.3" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 102.4;Epididymal efferent duct absorptive cells: 146.4;Esophageal apical cells: 146.7;Ocular epithelial cells: 169.0;Oocytes: 110.5" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 146.7;Barrier epithelial cells: 169.0;Ductal cells: 146.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 18.5" "Group enriched" "Detected in many" 6 "monocytes: 5.6;T-cells: 18.5" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA007935 Uncertain Supported "Nuclear bodies" NA Yes "Cluster 1: T-cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 17 "Nuclear bodies" "HPA007935: " "unprognostic (8.14e-2)" "unprognostic (4.08e-3)" "unprognostic (6.78e-2)" "unprognostic (4.45e-2)" "unprognostic (7.13e-2)" "unprognostic (5.22e-1)" "unprognostic (2.69e-2)" "unprognostic (2.80e-2)" "unprognostic (4.15e-2)" "unprognostic (2.67e-1)" "unprognostic (2.65e-2)" "potential prognostic favorable (1.78e-4)" "unprognostic (7.14e-3)" "unprognostic (2.34e-2)" "unprognostic (3.57e-1)" "unprognostic (6.07e-2)" "unprognostic (2.24e-3)" "unprognostic (1.73e-1)" "unprognostic (1.14e-1)" "unprognostic (1.72e-3)" "unprognostic (1.62e-1)" "unprognostic (1.20e-2)" "unprognostic (2.31e-2)" "unprognostic (2.28e-1)" "unprognostic (1.61e-1)" "unprognostic (9.12e-2)" "unprognostic (2.82e-3)" "unprognostic (2.28e-3)" "unprognostic (2.75e-1)" "unprognostic (2.92e-1)" "unprognostic (9.59e-3)" NR1H4 "FXR, HRR-1, HRR1, RIP14" ENSG00000012504 "Nuclear receptor subfamily 1 group H member 4" Q96RI1 12 100473708-100564414 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Immunity, Inflammatory response, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Disease variant, FDA approved drug targets, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 36.8;liver: 112.7" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 212.1;Cholangiocytes: 212.2;Enteric transient amplifying cells: 137.8;Enterocytes: 673.5;Hepatic stellate cells: 154.9;Hepatocytes: 255.6;Loop of henle epithelial cells: 82.8;Oocytes: 138.2;Paneth cells: 77.3;Proximal tubule cells: 174.9;Renal collecting duct principal cells: 82.3;Urothelial cells: 87.0" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 212.1;Ductal cells: 212.2;Enterocytes: 673.5;Hepatocytes: 255.6" "Group enriched" "Detected in some" 5 "ependymal cell: 24.3;vascular associated smooth muscle cell: 13.6" "Group enriched" "Detected in many" 10 "Kidney Renal Clear Cell Carcinoma (TCGA): 37.4;Kidney Renal Papillary Cell Carcinoma (TCGA): 37.4;Liver Hepatocellular Carcinoma (TCGA): 40.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 3.8;Kidney cancer: 14.8;liver cancer: 12.1" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5765 "Skeletal myofibers: 576473.4" "Not detected" "Not detected" HPA047699 Supported "Nucleoplasm,Nuclear speckles,Primary cilium tip,Cytosol" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" 13 "Nucleoplasm, Nuclear speckles" "Primary cilium tip, Cytosol" "HPA047699: " "unprognostic (3.35e-1)" "unprognostic (7.52e-2)" "unprognostic (4.48e-2)" "unprognostic (2.87e-1)" "potential prognostic favorable (7.74e-4)" "unprognostic (1.94e-2)" "unprognostic (1.55e-1)" "unprognostic (1.59e-1)" "unprognostic (7.80e-2)" "unprognostic (7.18e-2)" "unprognostic (2.10e-2)" "unprognostic (3.86e-3)" "unprognostic (3.52e-1)" "unprognostic (1.55e-1)" NR2E1 "TLL, TLX, XTLL" ENSG00000112333 "Nuclear receptor subfamily 2 group E member 1" Q9Y466 6 108166022-108188805 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 56 "brain: 23.9;choroid plexus: 7.8;retina: 28.4" "Cell type enriched" "Detected in some" 4 "Müller glia: 91.3" "Cell type enriched" "Detected in some" 6 "Glial cells: 91.3" "Group enriched" "Detected in some" 4 "astrocyte: 15.9;CGE interneuron: 26.1;choroid plexus epithelial cell: 7.4" "Cancer enriched" "Detected in some" 9 "Glioblastoma Multiforme (TCGA): 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 2.5" "Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 21 "Neurons: 2126.4" "Tissue enriched" "Detected in some" "pancreas: 1526464.7" "HPA036954, HPA055642" Uncertain Approved "Nuclear bodies" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Muller glia cells - Retinal homeostasis" 8 "Nuclear bodies" "HPA036954: , HPA055642: " "unprognostic (1.25e-1)" "potential prognostic unfavorable (9.28e-6)" "unprognostic (7.83e-2)" "unprognostic (3.06e-1)" NR3C1 "GR, GRL" ENSG00000113580 "Nuclear receptor subfamily 3 group C member 1" P04150 5 143277931-143435512 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Receptor, RNA-binding" "Disease variant, FDA approved drug targets, Pseudohermaphroditism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Corticotrophs: 1168.5;Myonuclei: 691.5;Neutrophils: 1012.2;pDCs: 861.8" "Cell type enhanced" "Detected in all" "Pituitary endocrine cells: 1168.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "intestine: 69440780.3" "HPA004248, CAB010435" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 9: T-cells - Adaptive immunity: Regulation" 122 "Nucleoplasm, Cytosol" Mitochondria "CAB010435: , HPA004248: " "unprognostic (9.89e-2)" "unprognostic (2.02e-1)" "unprognostic (1.77e-2)" "unprognostic (1.21e-1)" "unprognostic (9.03e-2)" "unprognostic (3.09e-1)" "unprognostic (6.11e-2)" "unprognostic (1.73e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (1.01e-5)" "potential prognostic favorable (9.64e-5)" "unprognostic (2.33e-2)" "unprognostic (8.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.06e-3)" "unprognostic (2.63e-1)" "unprognostic (1.33e-1)" "unprognostic (4.87e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-2)" "unprognostic (1.30e-2)" "unprognostic (2.20e-1)" "unprognostic (5.84e-3)" "unprognostic (1.24e-1)" "unprognostic (1.75e-1)" "unprognostic (2.57e-2)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (5.86e-2)" "unprognostic (4.19e-3)" "unprognostic (2.20e-2)" NR4A1 "GFRP1, HMR, N10, NAK-1, NGFIB, NUR77, TR3" ENSG00000123358 "Nuclear receptor subfamily 4 group A member 1" P22736 12 52022832-52059507 "Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Inflammatory response, Transcription, Transcription regulation" "DNA-binding, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast secretory cells: 820.7;Endometrial luminal cells: 1029.1;Epicardial cells: 1491.8;Ovarian stromal cells: 1172.8;Vascular smooth muscle cells: 825.0" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 1491.8" "Cell type enhanced" "Detected in all" "endothelial cell: 259.2;vascular associated smooth muscle cell: 497.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 36.7;non-classical monocyte: 54.4" "Lineage enriched" "Detected in many" 15 "monocytes: 54.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 5 "salivary gland: 479.3" "HPA027311, HPA059742, HPA070142" Approved Supported "Nucleoplasm,Nuclear membrane,Nucleoli fibrillar center,Nuclear speckles,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 103: Non-specific - Basic cellular processes" 48 Nucleoplasm "Nuclear membrane, Nucleoli fibrillar center, Nuclear speckles, Cytosol" "HPA027311: , HPA059742: , HPA070142: " "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.31e-2)" "unprognostic (1.36e-1)" "unprognostic (8.26e-2)" "unprognostic (2.93e-1)" "unprognostic (1.07e-1)" "unprognostic (1.57e-1)" "unprognostic (1.25e-1)" "unprognostic (7.08e-3)" "unprognostic (1.21e-3)" "potential prognostic favorable (1.61e-6)" "unprognostic (1.00e-1)" "unprognostic (3.56e-2)" "unprognostic (1.54e-2)" "unprognostic (3.49e-1)" "unprognostic (3.10e-3)" "unprognostic (7.85e-2)" "unprognostic (7.26e-2)" "unprognostic (1.78e-3)" "unprognostic (8.72e-3)" "unprognostic (1.93e-1)" "unprognostic (9.92e-2)" "unprognostic (9.25e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (3.56e-6)" "unprognostic (9.95e-3)" "unprognostic (3.63e-2)" "unprognostic (1.59e-1)" "unprognostic (9.48e-3)" "unprognostic (5.86e-2)" NR5A1 "AD4BP, ELP, FTZ1, FTZF1, hSF-1, SF-1, SF1" ENSG00000136931 "Nuclear receptor subfamily 5 group A member 1" Q13285 9 124481236-124507420 "Disease related genes, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "Disease variant, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "adrenal gland: 182.1;lymphoid tissue: 136.6" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 89.5;Adrenal medulla cells: 10.6;Gonadotrophs: 100.0;Granulosa cells: 23.5;Leydig cells: 25.4;Lymphatic endothelial cells: 15.1;Ovarian stromal cells: 19.1;Peritubular myoid cells: 16.0;Platelets: 11.3;Sertoli cells: 17.2" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 89.5;Leydig cells: 25.4;Pituitary endocrine cells: 100.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 4.1;Testicular Germ Cell Tumor (TCGA): 4.8" "Region enriched" "Detected in single" 50 "hypothalamus: 37.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "head and neck cancer: 1.9;Leukemia: 3.2;liver cancer: 3.7" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes, Spleen - Endothelial cells" "Region enriched" "Detected in single" 52 "hypothalamus: 5.2" "Region enriched" "Detected in single" 8 "hypothalamus: 1.6" "Cell type enriched" "Detected in single" 6754 "Granulosa cells: 675439.6" "Not detected" "Not detected" HPA079181 Supported Nucleoplasm,Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 20 Nucleoplasm Cytosol "HPA079181: " "unprognostic (2.13e-1)" "unprognostic (6.37e-2)" "unprognostic (2.65e-2)" "unprognostic (3.33e-2)" "unprognostic (4.39e-2)" "unprognostic (6.60e-2)" NRAP ENSG00000197893 "Nebulin related anchoring protein" Q86VF7 10 113588714-113664070 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 2213.4;tongue: 1069.5" "Group enriched" "Detected in some" 39 "Cardiomyocytes: 632.9;Myonuclei: 1072.1;Thymic myoid cells: 425.6" "Group enriched" "Detected in many" 41 "Myocytes: 1072.1;Stromal cells: 425.6" "Cell type enhanced" "Detected in some" "deep-layer intratelencephalic: 1.6;thalamic excitatory: 1.2" "Group enriched" "Detected in some" 6 "Head and Neck Squamous Cell Carcinoma (TCGA): 12.4;Prostate Adenocarcinoma (TCGA): 4.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" "Cardiomyocytes: 103833801.1;Skeletal myofibers: 221066983.2" "Group enriched" "Detected in some" 563594 "heart muscle: 34773303.9;skeletal muscle: 77945555.3" "HPA037953, HPA037954, HPA075074" Enhanced Approved "Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 55: Myocytes - Oxidative muscle function" 4 "Intermediate filaments" "Vesicles, Cytosol" "HPA037953: , HPA037954: , HPA075074: " "unprognostic (3.68e-2)" "unprognostic (1.71e-3)" "unprognostic (1.07e-1)" "unprognostic (1.77e-1)" NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 35.1;brain: 101.7;retina: 34.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1220.5;Adrenal medulla cells: 542.5;Astrocytes: 935.1;Bergmann glia: 1268.7;Brain excitatory neurons: 588.9;Cone photoreceptor cells: 743.2;Corticotrophs: 769.9;Lactotrophs: 703.3;Oligodendrocyte progenitor cells: 1948.9;Pituitary stem cells: 2103.7;Somatotrophs: 570.3;Thyrotrophs: 747.3" "Group enriched" "Detected in many" 4 "Adrenal endocrine cells: 1220.5;Glial cells: 1948.9;Neuronal cells: 743.2;Pituitary endocrine cells: 769.9;Stem cells: 2103.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 79.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.1" "Lineage enriched" "Detected in single" 15 "T-cells: 2.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Pituitary gland - Lactotropes, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 150746978.8;Microglia and Neuropil: 137797537.5;Neurons: 47196805.3" "Tissue enriched" "Detected in many" "cerebral cortex: 529841320.3" "HPA012606, CAB080588" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Cytosol" "Secreted in brain" "Cell adhesion" NA NA 39000000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 72: Neuronal - Signal transduction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 1 Nucleoplasm "Vesicles, Plasma membrane, Primary cilium, Cytosol" "CAB080588: , HPA012606: " "unprognostic (1.75e-1)" "unprognostic (4.03e-1)" "unprognostic (2.17e-1)" "unprognostic (1.44e-1)" "unprognostic (2.31e-2)" "unprognostic (2.78e-1)" "unprognostic (2.95e-2)" "unprognostic (6.59e-3)" "unprognostic (3.11e-2)" "unprognostic (1.16e-3)" "potential prognostic favorable (6.74e-6)" "unprognostic (4.36e-3)" "unprognostic (1.35e-1)" "unprognostic (1.76e-3)" "unprognostic (1.76e-2)" "unprognostic (7.92e-2)" "unprognostic (2.10e-1)" "unprognostic (4.16e-3)" "unprognostic (4.21e-2)" "unprognostic (4.14e-1)" "unprognostic (5.67e-2)" "unprognostic (1.80e-2)" "unprognostic (2.81e-2)" "unprognostic (1.19e-1)" "unprognostic (1.80e-1)" "unprognostic (3.11e-2)" "unprognostic (3.63e-3)" "unprognostic (3.39e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-1)" NRG2 "Don-1, HRG2, NTAK" ENSG00000158458 "Neuregulin 2" O14511 5 139846779-140043299 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins" "Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 176.6;Brain inhibitory neurons: 208.6;Ependymal cells: 161.9;Oligodendrocyte progenitor cells: 201.7;Other brain neurons: 131.2;Retinal amacrine cells: 191.9;Salivary acinar cells: 151.6;Thyrotrophs: 186.7" "Cell type enhanced" "Detected in many" "Glial cells: 201.7;Neuronal cells: 208.6;Pituitary endocrine cells: 186.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 11.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA038935, HPA047973" Approved Supported Nucleoplasm,Nucleoli "Secreted in other tissues" "Growth factor" No NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 82: Dendritic cells - Antigen presentation" 3 Nucleoplasm Nucleoli "HPA038935: , HPA047973: " "unprognostic (1.11e-1)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (6.02e-2)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (2.07e-1)" NRIP2 DKFZP761G1913 ENSG00000053702 "Nuclear receptor interacting protein 2" Q9BQI9 12 2825348-2835544 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 16.7;brain: 55.5" "Cell type enhanced" "Detected in many" "Adipocytes: 7.4;Brain excitatory neurons: 8.3;Cardiomyocytes: 41.6;Epicardial cells: 25.0;Fibro-adipogenic progenitors: 7.4;Myonuclei: 8.7;Podocytes: 20.9;Vascular smooth muscle cells: 20.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 25.0;Mural cells: 20.7;Myocytes: 41.6;Renal nephron cells: 20.9" "Cell type enhanced" "Detected in many" "upper rhombic lip: 17.8;vascular associated smooth muscle cell: 28.0" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 17.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "basophil: 3.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 3.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Smooth muscle cells, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Glomeruli: 11313006.6" "Tissue enhanced" "Detected in many" "ovary: 4530058.7" "HPA039197, HPA039860" Enhanced Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 71: Cerebellum - Nervous system development" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 62: Smooth muscle cells - Muscle contraction" 2 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA039197: , HPA039860: " "unprognostic (2.38e-1)" "unprognostic (4.60e-2)" "unprognostic (8.03e-2)" "unprognostic (3.60e-2)" "unprognostic (2.27e-3)" "unprognostic (3.58e-1)" "unprognostic (7.60e-2)" "potential prognostic favorable (1.32e-4)" "unprognostic (4.36e-2)" "validated prognostic favorable (7.42e-4)" "validated prognostic favorable (1.32e-4)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (8.10e-3)" "unprognostic (1.43e-1)" "unprognostic (8.81e-2)" "unprognostic (1.52e-1)" "unprognostic (8.37e-2)" "unprognostic (4.69e-2)" "potential prognostic favorable (2.15e-4)" "unprognostic (2.40e-1)" "unprognostic (5.74e-3)" "unprognostic (1.53e-1)" "unprognostic (3.23e-2)" "unprognostic (5.48e-2)" "unprognostic (9.51e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-1)" "unprognostic (2.38e-2)" NRP1 "CD304, NRP, VEGF165R" ENSG00000099250 "Neuropilin 1" O14786 10 33177492-33336262 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Angiogenesis, Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 546.5;Endometrial stromal cells: 339.2;Fibro-adipogenic progenitors: 371.6;Hofbauer cells: 616.3;Kupffer cells: 469.4;Macrophages: 453.0;Medullary thymic epithelial cells: 410.4;pDCs: 321.7;Pericytes: 357.2;Proximal tubule cells: 611.9;Vascular endothelial cells: 593.1" "Cell type enhanced" "Detected in many" "Adipocytes: 546.5;Endothelial cells: 593.1;Mononuclear phagocytes: 616.3;Renal nephron cells: 611.9" "Cell type enhanced" "Detected in all" "hippocampal CA4: 1340.3;hippocampal dentate gyrus: 669.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 170.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 39.4" "Lineage enriched" "Detected in many" 16 "dendritic cells: 39.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 4482766.2" "Group enriched" "Detected in all" "heart muscle: 3475461.4;skeletal muscle: 13871393.6" "CAB004511, HPA030278" Approved Uncertain Mitochondria "Secreted in other tissues" Receptor NA NA 270000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 32 Mitochondria "CAB004511: , HPA030278: " "unprognostic (1.03e-1)" "unprognostic (3.53e-1)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (2.16e-6)" "unprognostic (2.32e-2)" "unprognostic (1.06e-2)" "unprognostic (2.37e-3)" "unprognostic (2.91e-1)" "unprognostic (2.74e-2)" "unprognostic (3.99e-2)" "validated prognostic favorable (4.67e-7)" "validated prognostic favorable (4.70e-4)" "unprognostic (1.42e-1)" "unprognostic (8.80e-3)" "unprognostic (3.60e-1)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (2.31e-2)" "unprognostic (3.57e-2)" "unprognostic (8.67e-2)" "unprognostic (1.69e-1)" "unprognostic (1.15e-1)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (8.75e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (3.33e-5)" "unprognostic (9.02e-2)" "unprognostic (2.75e-2)" "unprognostic (3.49e-1)" NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 73.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 145.2;Epididymal basal cells: 153.3;Hofbauer cells: 377.9;Lymphatic endothelial cells: 427.9;Macrophages: 210.5;Smooth muscle cells: 215.8;Transitional alveolar cells: 183.6;Vascular endothelial cells: 150.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 427.9;Mononuclear phagocytes: 377.9" "Cell type enhanced" "Detected in all" "mammillary body: 448.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 122.1" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" Receptor NA NA 28000000 "Cluster 75: Ovary - Mixed function" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" 2 "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: , HPA054974: " "unprognostic (3.32e-2)" "unprognostic (7.02e-2)" "unprognostic (1.37e-1)" "unprognostic (2.56e-1)" "unprognostic (1.18e-2)" "unprognostic (4.12e-2)" "unprognostic (1.96e-1)" "unprognostic (5.25e-2)" "unprognostic (2.80e-2)" "unprognostic (6.22e-3)" "unprognostic (1.90e-2)" "unprognostic (4.99e-3)" "unprognostic (1.06e-2)" "unprognostic (6.40e-2)" "unprognostic (1.14e-2)" "unprognostic (2.63e-2)" "unprognostic (2.41e-3)" "unprognostic (1.12e-1)" "unprognostic (3.24e-1)" "unprognostic (5.31e-3)" "unprognostic (6.36e-2)" "unprognostic (2.89e-3)" "unprognostic (5.78e-2)" "unprognostic (2.72e-1)" "unprognostic (6.58e-2)" "unprognostic (2.30e-3)" "unprognostic (3.26e-3)" "unprognostic (2.67e-3)" "unprognostic (3.39e-2)" "unprognostic (2.12e-2)" "unprognostic (3.04e-1)" NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Intellectual disability, Schizophrenia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 75.9" "Cell type enhanced" "Detected in many" "Astrocytes: 5666.4;Brain excitatory neurons: 4367.9;Brain inhibitory neurons: 2457.1;Corticotrophs: 4225.1;Ependymal cells: 1563.6;Gonadotrophs: 1381.5;Lactotrophs: 1179.4;Oligodendrocyte progenitor cells: 6784.3;Other brain neurons: 2385.1;Schwann cells: 3656.1;Thyrotrophs: 1451.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 1563.6;Glial cells: 6784.3;Neuronal cells: 4367.9;Pituitary endocrine cells: 4225.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 16.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Lineage enriched" "Detected in single" 12 "granulocytes: 1.5" "Cancer enhanced" "Detected in some" "lung cancer: 4.4;thyroid cancer: 4.6" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 22210413.2;Microglia and Neuropil: 29569139.6;Neurons: 20938990.1" "Tissue enriched" "Detected in single" 440791 "cerebral cortex: 44079050.4" HPA071400 Approved "Nucleoplasm,Nucleoli,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 1100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 2: Neurons - Nucleosome" "Cluster 65: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA071400: " "unprognostic (3.33e-2)" "unprognostic (2.60e-1)" "unprognostic (5.04e-1)" "unprognostic (4.06e-3)" "unprognostic (4.25e-1)" "unprognostic (8.80e-2)" "potential prognostic favorable (3.42e-4)" "unprognostic (8.55e-2)" "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" NSA2 "FLJ94393, HCLG1, HUSSY-29, TINP1" ENSG00000164346 "NSA2 ribosome biogenesis factor" O95478 5 74766991-74780113 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribosome biogenesis, rRNA processing" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 611.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Cell type enhanced" "Detected in many" "Macrophages: 13924522.4;T-cells: 11551931.4" "Group enriched" "Detected in some" 8632 "cerebral cortex: 331686.0;fallopian tube: 1186058.5;lymphoid tissue: 1071927.3" HPA043487 Approved Enhanced Nucleoplasm,Nucleoli No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 15: Non-specific - Protein processing" 66 "Nucleoplasm, Nucleoli" "HPA043487: " "unprognostic (1.99e-1)" "unprognostic (6.12e-2)" "unprognostic (2.59e-1)" "unprognostic (2.79e-1)" "unprognostic (4.07e-2)" "unprognostic (8.23e-2)" "unprognostic (4.27e-2)" "unprognostic (9.10e-2)" "unprognostic (2.28e-2)" "unprognostic (6.11e-2)" "validated prognostic favorable (1.24e-5)" "validated prognostic favorable (9.18e-4)" "unprognostic (2.92e-1)" "unprognostic (2.44e-2)" "unprognostic (2.04e-3)" "unprognostic (1.82e-1)" "unprognostic (8.07e-2)" "unprognostic (6.30e-2)" "unprognostic (1.51e-2)" "unprognostic (1.22e-1)" "unprognostic (1.79e-1)" "unprognostic (2.30e-1)" "unprognostic (5.79e-2)" "unprognostic (6.11e-2)" "unprognostic (3.35e-1)" "unprognostic (8.75e-2)" "unprognostic (1.11e-2)" "unprognostic (5.32e-2)" "unprognostic (2.35e-1)" "unprognostic (2.56e-1)" "unprognostic (1.83e-1)" NSD2 "KMT3G, MMSET, WHSC1" ENSG00000109685 "Nuclear receptor binding SET domain protein 2" O96028 4 1871393-1982207 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 342.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Smooth muscle cells: 6384166.4" "Tissue enriched" "Detected in single" 334 "bone marrow: 33382.7" "HPA015801, CAB068246, CAB068247" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 20: Non-specific - DNA binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 27: Non-specific - Cell proliferation" 77 Nucleoplasm Nucleoli "CAB068246: , CAB068247: , HPA015801: " "unprognostic (3.83e-1)" "unprognostic (1.46e-1)" "unprognostic (5.99e-2)" "unprognostic (4.90e-3)" "unprognostic (1.74e-1)" "unprognostic (1.96e-1)" "unprognostic (2.91e-3)" "unprognostic (5.57e-3)" "unprognostic (2.25e-3)" "unprognostic (5.20e-2)" "unprognostic (8.76e-2)" "unprognostic (2.55e-1)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (9.03e-3)" "unprognostic (3.41e-3)" "unprognostic (6.01e-2)" "unprognostic (3.67e-2)" "unprognostic (3.19e-1)" "unprognostic (3.40e-2)" "unprognostic (1.55e-1)" "unprognostic (1.41e-2)" "unprognostic (2.36e-2)" "unprognostic (1.74e-3)" "unprognostic (1.59e-1)" "unprognostic (8.56e-2)" "unprognostic (3.27e-2)" "unprognostic (2.58e-1)" "unprognostic (3.79e-2)" "unprognostic (2.17e-1)" NSDHL "H105e3, SDR31E1, XAP104" ENSG00000147383 "NAD(P) dependent steroid dehydrogenase-like" Q15738 X 152830967-152869729 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 70.7;Epididymal principal cells: 144.0;Esophageal apical cells: 238.6;Esophageal suprabasal cells: 95.0;Oocytes: 147.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 238.6;Oocytes: 147.4;Reproductive supporting cells: 144.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Colon - Macrophages, Skin - Sebaceous gland cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "liver: 18831300.6" "HPA000248, HPA000571" Enhanced Enhanced "Endoplasmic reticulum,Lipid droplets" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 37 "Endoplasmic reticulum" "Lipid droplets" "HPA000248: , HPA000571: " "unprognostic (3.04e-2)" "unprognostic (1.61e-2)" "unprognostic (1.68e-1)" "unprognostic (1.67e-1)" "unprognostic (6.50e-2)" "unprognostic (2.62e-1)" "unprognostic (2.21e-1)" "unprognostic (1.96e-1)" "unprognostic (1.00e-2)" "unprognostic (2.71e-3)" "potential prognostic favorable (1.17e-7)" "unprognostic (1.11e-2)" "unprognostic (3.26e-1)" "validated prognostic unfavorable (4.65e-4)" "validated prognostic unfavorable (4.15e-4)" "unprognostic (4.66e-2)" "unprognostic (1.47e-3)" "unprognostic (1.41e-1)" "unprognostic (2.19e-1)" "unprognostic (7.81e-2)" "unprognostic (1.95e-2)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "unprognostic (1.18e-1)" "unprognostic (5.53e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (1.19e-1)" "unprognostic (4.07e-2)" "unprognostic (2.69e-2)" "unprognostic (1.53e-1)" NSF "SEC18, SKD2" ENSG00000073969 "N-ethylmaleimide sensitive factor, vesicle fusing ATPase" P46459 17 46590669-46757679 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" Hydrolase "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 145.0" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 150.3;Brain inhibitory neurons: 184.5;Distal convoluted tubule cells: 142.6;Loop of henle epithelial cells: 123.5;Microglia: 76.0;Oligodendrocyte progenitor cells: 66.9;Other brain neurons: 157.3;Papillary tip epithelial cells: 151.0;Podocytes: 91.4;Proximal tubule cells: 86.0;Renal collecting duct intercalated cells: 109.0;Renal collecting duct principal cells: 147.3;Renal connecting tubule cells: 129.8" "Cell type enhanced" "Detected in many" "Ductal cells: 147.3;Glial cells: 76.0;Neuronal cells: 184.5;Renal nephron cells: 151.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Pituitary gland - Lactotropes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 883777952.2;Microglia and Neuropil: 1080532241.6" "Tissue enriched" "Detected in all" "cerebral cortex: 1250855965.1" "HPA003154, CAB009324, HPA071089" Enhanced Supported "Golgi apparatus,Cytosol,Acrosome,Equatorial segment,Mid piece,Principal piece,End piece" NA NA 88000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 102 "Golgi apparatus, Cytosol" "Acrosome, Equatorial segment, Mid piece, Principal piece, End piece" "CAB009324: , HPA003154: , HPA071089: " "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "unprognostic (3.81e-2)" "unprognostic (9.70e-2)" "potential prognostic favorable (5.87e-4)" "unprognostic (9.23e-2)" "unprognostic (2.33e-1)" "unprognostic (3.47e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (9.71e-4)" "unprognostic (1.05e-3)" "unprognostic (3.52e-1)" "unprognostic (2.03e-1)" "unprognostic (4.28e-2)" "unprognostic (2.90e-1)" "unprognostic (5.76e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (1.07e-4)" "unprognostic (1.12e-1)" "unprognostic (3.90e-2)" "unprognostic (1.06e-1)" "unprognostic (2.66e-2)" "unprognostic (1.61e-1)" "unprognostic (2.08e-2)" "unprognostic (1.60e-1)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" "unprognostic (1.13e-1)" NSFL1C "dJ776F14.1, p47, UBX1, UBXD10, UBXN2C" ENSG00000088833 "NSFL1 cofactor" Q9UNZ2 20 1442162-1473842 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 234.1;Oocytes: 271.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA047108, HPA050628" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 4300000 "Cluster 22: Eosinophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 24: Neutrophils - Innate immunity signal integration" 23 Nucleoplasm "Plasma membrane, Cytosol" "HPA047108: , HPA050628: " "unprognostic (4.31e-2)" "unprognostic (3.98e-2)" "unprognostic (2.03e-1)" "unprognostic (3.64e-2)" "unprognostic (2.65e-1)" "unprognostic (1.80e-3)" "unprognostic (6.44e-2)" "unprognostic (2.90e-1)" "unprognostic (4.33e-2)" "unprognostic (2.21e-1)" "unprognostic (1.15e-3)" "unprognostic (2.50e-1)" "unprognostic (2.92e-2)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (4.04e-3)" "unprognostic (1.76e-2)" "unprognostic (3.60e-2)" "unprognostic (1.31e-2)" "unprognostic (4.69e-2)" "unprognostic (1.18e-1)" "unprognostic (4.05e-2)" "unprognostic (3.12e-1)" "unprognostic (3.43e-2)" "unprognostic (3.19e-2)" "unprognostic (2.06e-1)" "unprognostic (3.47e-1)" "unprognostic (2.39e-1)" "unprognostic (9.19e-2)" "unprognostic (2.79e-1)" "unprognostic (4.05e-2)" "unprognostic (1.70e-1)" NSG2 "CALY3, HMP19" ENSG00000170091 "Neuronal vesicle trafficking associated 2" Q9Y328 5 174045706-174243501 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 442.8" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 95.7;Brain excitatory neurons: 115.4;Brain inhibitory neurons: 264.7;Early spermatids: 77.1;Late primary spermatocytes: 50.4;Late spermatids: 43.1;Oligodendrocyte progenitor cells: 176.3;Other brain neurons: 175.9;Retinal amacrine cells: 253.8;Retinal horizontal cells: 86.1" "Group enriched" "Detected in many" 12 "Adrenal endocrine cells: 95.7;Glial cells: 176.3;Neuronal cells: 264.7;Spermatogenic cell types: 77.1" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 8 "Glioblastoma Multiforme (TCGA): 34.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Neuroblastoma: 170.6;thyroid cancer: 79.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pituitary gland - Thyrotropes, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7264 "Microglia and Neuropil: 502548.3;Neurons: 950173.5" "Tissue enriched" "Detected in single" 3473 "cerebral cortex: 347339.3" "HPA046531, HPA056191" Enhanced Enhanced "Golgi apparatus" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Golgi apparatus" "HPA046531: , HPA056191: " "unprognostic (4.83e-2)" "unprognostic (2.24e-1)" "unprognostic (1.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.86e-1)" "unprognostic (1.44e-2)" "unprognostic (5.17e-1)" NSUN5 "FLJ10267, NOL1R, NSUN5A, p120(NOL1), WBSCR20, WBSCR20A, Ynl022cL" ENSG00000130305 "NOP2/Sun RNA methyltransferase 5" Q96P11 7 73302516-73308826 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Methyltransferase, RNA-binding, Transferase" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 60.2;Neutrophil progenitors: 109.7;Oocytes: 138.2" "Cell type enhanced" "Detected in many" "Neutrophils: 109.7;Oocytes: 138.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 21703259.7;T-cells: 18669163.7" "Tissue enhanced" "Detected in many" "intestine: 8559104.2" "HPA020536, HPA045590, HPA046867" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 39: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "Nucleoplasm, Nucleoli" "HPA020536: , HPA045590: , HPA046867: " "unprognostic (9.60e-3)" "unprognostic (6.87e-2)" "unprognostic (1.49e-1)" "unprognostic (1.26e-1)" "unprognostic (1.65e-1)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (1.91e-3)" "unprognostic (2.61e-1)" "unprognostic (1.11e-1)" "unprognostic (2.77e-3)" "unprognostic (1.72e-2)" "unprognostic (9.09e-2)" "potential prognostic unfavorable (1.81e-7)" "unprognostic (8.65e-3)" "unprognostic (5.48e-2)" "unprognostic (8.51e-2)" "unprognostic (2.37e-1)" "unprognostic (5.00e-1)" "unprognostic (3.79e-2)" "unprognostic (6.31e-3)" "unprognostic (9.05e-2)" "unprognostic (3.04e-1)" "unprognostic (1.77e-1)" "unprognostic (2.79e-1)" "unprognostic (1.46e-1)" "unprognostic (1.50e-2)" "unprognostic (1.36e-1)" "unprognostic (3.42e-1)" "unprognostic (2.88e-1)" "unprognostic (1.22e-1)" NSUN7 FLJ14001 ENSG00000179299 "NOP2/Sun RNA methyltransferase family member 7" Q8NE18 4 40749925-40811184 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 15.4" "Cell type enhanced" "Detected in many" "Ependymal cells: 131.5;Fallopian tube ciliated cells: 137.1;Late spermatids: 163.6;Neutrophils: 275.2;Respiratory ciliated cells: 366.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 366.2;Neutrophils: 275.2" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 93.0;ependymal cell: 140.6" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 13.6" "Region enhanced" "Detected in all" "choroid plexus: 15.6" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.7" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Hepatocytes: 3170279.0" "Tissue enriched" "Detected in single" 276 "intestine: 27605.6" HPA020653 Uncertain Approved Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 24: Neutrophils - Innate immunity signal integration" Vesicles "HPA020653: " "unprognostic (7.77e-3)" "unprognostic (1.37e-1)" "unprognostic (3.39e-1)" "unprognostic (1.20e-2)" "unprognostic (2.46e-2)" "unprognostic (2.19e-1)" "unprognostic (3.50e-2)" "potential prognostic unfavorable (5.56e-6)" "unprognostic (7.12e-2)" "potential prognostic favorable (1.44e-5)" "unprognostic (2.11e-3)" "potential prognostic favorable (3.31e-4)" "unprognostic (3.24e-2)" "unprognostic (3.10e-1)" "unprognostic (1.10e-1)" "unprognostic (1.19e-1)" "unprognostic (7.39e-2)" "unprognostic (4.53e-3)" "unprognostic (3.15e-1)" "unprognostic (1.12e-1)" "unprognostic (6.09e-2)" "unprognostic (6.24e-3)" "unprognostic (8.76e-3)" "unprognostic (1.81e-1)" "unprognostic (1.36e-1)" "unprognostic (1.68e-1)" "unprognostic (3.47e-1)" NT5C3A "cN-III, hUMP1, NT5C3, p36, P5'N-1, PN-I, POMP, PSN1, UMPH, UMPH1" ENSG00000122643 "5'-nucleotidase, cytosolic IIIA" Q9H0P0 7 33014130-33062796 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 82.6" "Cell type enriched" "Detected in all" 4 "Platelets: 1661.6" "Cell type enriched" "Detected in all" 4 "Platelets: 1661.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 126268538.0" "Tissue enriched" "Detected in all" "skeletal muscle: 97845642.3" "HPA010520, HPA010630, HPA029058" Uncertain Supported "Nucleoplasm,Nuclear bodies,Endoplasmic reticulum,Cytosol" NA NA 23000 "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 47: Platelets - Hemostasis" 5 "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA010520: , HPA010630: , HPA029058: " "unprognostic (2.59e-2)" "unprognostic (4.07e-2)" "unprognostic (4.39e-3)" "unprognostic (7.33e-2)" "unprognostic (9.81e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.13e-1)" "unprognostic (8.44e-2)" "unprognostic (2.06e-2)" "potential prognostic unfavorable (3.96e-4)" "potential prognostic unfavorable (5.59e-4)" "unprognostic (9.28e-3)" "unprognostic (2.22e-1)" "unprognostic (1.75e-1)" "unprognostic (3.62e-2)" "unprognostic (9.62e-2)" "unprognostic (1.40e-3)" "unprognostic (7.42e-2)" "unprognostic (5.09e-2)" "unprognostic (1.55e-1)" "unprognostic (1.58e-1)" "unprognostic (4.62e-3)" "unprognostic (3.14e-1)" "unprognostic (2.74e-1)" "unprognostic (5.52e-3)" "unprognostic (4.50e-2)" NT5DC3 "FLJ11266, TU12B1-TY" ENSG00000111696 "5'-nucleotidase domain containing 3" Q86UY8 12 103770453-103841234 "Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.2" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 122.0;Neutrophil progenitors: 160.5;Salivary acinar cells: 135.6;Salivary basal cells: 163.0;Salivary myoepithelial cells: 119.2;Smooth muscle cells: 130.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 31824613.8;Neurons: 27572867.6" "Tissue enhanced" "Detected in many" "cerebral cortex: 8861095.0;lymphoid tissue: 4255561.5" HPA041634 Approved Mitochondria,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Mitochondria Cytosol "HPA041634: " "unprognostic (2.44e-1)" "unprognostic (1.48e-1)" "unprognostic (1.41e-1)" "unprognostic (9.76e-2)" "unprognostic (1.52e-1)" "unprognostic (7.51e-2)" "unprognostic (8.72e-2)" "unprognostic (6.80e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.68e-1)" "unprognostic (2.54e-2)" "unprognostic (5.25e-3)" "validated prognostic unfavorable (7.99e-6)" "validated prognostic unfavorable (3.04e-5)" "unprognostic (2.12e-2)" "unprognostic (1.01e-3)" "unprognostic (6.44e-2)" "potential prognostic favorable (2.81e-4)" "unprognostic (4.53e-3)" "unprognostic (9.25e-2)" "unprognostic (8.16e-2)" "unprognostic (2.82e-1)" "unprognostic (3.07e-1)" "unprognostic (1.54e-1)" "unprognostic (9.38e-2)" "unprognostic (2.19e-1)" "unprognostic (2.27e-2)" "unprognostic (3.35e-2)" "unprognostic (7.70e-2)" "unprognostic (1.94e-2)" NTAN1 ENSG00000157045 "N-terminal asparagine amidase" Q96AB6 16 15037854-15056079 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 42.0;Lymphatic endothelial cells: 48.1;Oocytes: 92.1;Platelets: 40.8;Urothelial cells: 36.6" "Cell type enhanced" "Detected in many" "Oocytes: 92.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 17.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Oocytes: 2395528.9" "Group enriched" "Detected in many" "skin: 1457759.6;Stomach: 2889587.3" HPA051418 Approved "Nucleoplasm,Golgi apparatus" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 74: Non-specific - Signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 4 Nucleoplasm "Golgi apparatus" "HPA051418: " "unprognostic (3.41e-3)" "unprognostic (3.11e-3)" "unprognostic (6.90e-2)" "unprognostic (7.64e-3)" "potential prognostic unfavorable (2.45e-4)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (8.35e-3)" "unprognostic (2.66e-2)" "unprognostic (2.80e-2)" "unprognostic (2.94e-2)" "unprognostic (2.44e-1)" "unprognostic (1.54e-1)" "unprognostic (9.36e-3)" "unprognostic (2.04e-1)" "unprognostic (7.79e-2)" "unprognostic (7.21e-2)" "unprognostic (1.29e-2)" "unprognostic (1.22e-1)" "unprognostic (5.34e-1)" NTAQ1 "C8orf32, FLJ10204, WDYHV1" ENSG00000156795 "N-terminal glutamine amidase 1" Q96HA8 8 123416726-123470028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 496268.2;Oocytes: 995905.3" "Tissue enhanced" "Detected in many" "heart muscle: 2154387.5;lymphoid tissue: 2214447.9" "HPA024823, HPA053680" Approved Supported Nucleoplasm,Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 329 Nucleoplasm Vesicles "HPA024823: , HPA053680: " "unprognostic (1.44e-1)" "unprognostic (1.65e-2)" "unprognostic (6.33e-2)" "unprognostic (4.95e-2)" "unprognostic (4.16e-2)" "unprognostic (1.89e-1)" "unprognostic (1.03e-2)" "unprognostic (1.75e-2)" "unprognostic (5.81e-3)" "unprognostic (9.68e-2)" "unprognostic (2.09e-1)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (7.54e-4)" "potential prognostic unfavorable (7.62e-4)" "unprognostic (5.24e-2)" "unprognostic (5.82e-2)" "unprognostic (7.66e-2)" "unprognostic (4.14e-2)" "unprognostic (1.01e-1)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (1.80e-5)" "unprognostic (2.94e-1)" "unprognostic (1.68e-1)" "unprognostic (2.26e-1)" "unprognostic (2.97e-1)" "unprognostic (2.62e-2)" "unprognostic (2.85e-1)" "unprognostic (3.32e-2)" "unprognostic (2.35e-1)" NTPCR "C1orf57, HCR-NTPase, MGC13186, THEP1" ENSG00000135778 "Nucleoside-triphosphatase, cancer-related" Q9BSD7 1 232950605-232983882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA028125, HPA054304" Uncertain Approved Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 16 Cytosol "HPA028125: , HPA054304: " "unprognostic (2.36e-2)" "unprognostic (1.48e-1)" "unprognostic (3.07e-2)" "unprognostic (4.43e-2)" "unprognostic (3.03e-1)" "unprognostic (1.13e-1)" "unprognostic (3.90e-2)" "unprognostic (4.57e-2)" "unprognostic (3.53e-2)" "unprognostic (3.17e-3)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (8.16e-4)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (7.09e-3)" "unprognostic (2.33e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" "unprognostic (3.83e-1)" "unprognostic (2.25e-2)" "unprognostic (1.97e-3)" "unprognostic (9.58e-2)" "unprognostic (2.09e-1)" "unprognostic (2.62e-1)" "unprognostic (3.97e-1)" "unprognostic (1.34e-1)" "unprognostic (3.59e-1)" "unprognostic (1.83e-1)" "unprognostic (4.08e-3)" "unprognostic (9.56e-2)" NTRK1 "MTC, TRK, TRKA" ENSG00000198400 "Neurotrophic receptor tyrosine kinase 1" P04629 1 156815636-156881850 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 6.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Decidual stromal cells: 19.7;Fibro-adipogenic progenitors: 20.8;Mast cells: 34.7;Megakaryocyte-Erythroid progenitors: 13.8;Other brain neurons: 19.0;Platelets: 15.5;Renal collecting duct intercalated cells: 18.8;Retinal bipolar cells: 49.9;Retinal horizontal cells: 52.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 31.9;Mast cells: 34.7;Neuronal cells: 52.1" "Cell type enhanced" "Detected in many" "fibroblast: 21.3;lower rhombic lip: 25.4" "Not detected" "Not detected" "Group enriched" "Detected in all" 5 "cerebral cortex: 23.8;medulla oblongata: 30.7;pons: 47.8" "Immune cell enriched" "Detected in single" 116 "basophil: 94.9" "Lineage enriched" "Detected in single" 772 "granulocytes: 94.9" "Group enriched" "Detected in some" 8 "Leukemia: 9.0;Neuroblastoma: 17.4" "Adrenal gland - Adrenal medulla cells, Kidney - Intercalated cells, Lung - Mast cells, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "basal ganglia: 8.4" "Region enriched" "Detected in single" 6 "basal ganglia: 5.4" "Cell type enriched" "Detected in some" "Cardiomyocytes: 828878.3" "Not detected" "Not detected" "CAB004606, HPA035799, HPA076570, CAB080140" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 49: Hindbrain - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 145 "Vesicles, Cytosol" "CAB004606: , CAB080140: , HPA035799: , HPA076570: " "unprognostic (2.30e-2)" "unprognostic (3.70e-2)" NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668375-85095751 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins, Transporters" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 233.3;thyroid gland: 118.0" "Cell type enhanced" "Detected in many" "Astrocytes: 2373.3;Bergmann glia: 364.4;Brain excitatory neurons: 502.7;Brain inhibitory neurons: 585.1;Breast lactating cells: 558.5;Choroid plexus epithelial cells: 430.8;Ependymal cells: 1515.5;Oligodendrocyte progenitor cells: 780.5;Retinal horizontal cells: 751.3;Vascular smooth muscle cells: 473.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 1515.5;Glial cells: 2373.3;Neuronal cells: 751.3" "Cell type enhanced" "Detected in all" "astrocyte: 2595.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 135.6;Thyroid Carcinoma (TCGA): 104.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 8.8;Esophageal cancer: 9.1" "Breast - Breast myoepithelial cells, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 7353583.6;Microglia and Neuropil: 13384584.5;Neurons: 8972687.3" "Tissue enriched" "Detected in single" 95008 "cerebral cortex: 9500763.5" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Vesicles,Plasma membrane,Primary cilium tip" NA NA 1700000 "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 28: Astrocytes - Homeostasis & neuron support" 25 "Plasma membrane" "Vesicles, Primary cilium tip" "CAB010346: , HPA007637: , HPA074873: " "unprognostic (1.74e-1)" "unprognostic (1.65e-3)" "unprognostic (4.55e-2)" "unprognostic (9.27e-2)" "unprognostic (4.97e-2)" "unprognostic (6.57e-2)" "unprognostic (1.93e-1)" "unprognostic (6.15e-2)" "unprognostic (3.51e-2)" "unprognostic (1.48e-3)" "potential prognostic favorable (1.81e-4)" "unprognostic (9.59e-2)" "unprognostic (2.95e-2)" "unprognostic (3.52e-2)" "unprognostic (1.51e-2)" "unprognostic (1.90e-2)" "unprognostic (2.15e-1)" "unprognostic (5.05e-2)" "unprognostic (2.15e-1)" "unprognostic (2.23e-2)" "unprognostic (2.71e-1)" "unprognostic (5.08e-3)" "unprognostic (8.42e-3)" "unprognostic (1.99e-2)" "unprognostic (2.25e-2)" "unprognostic (8.57e-2)" "unprognostic (3.68e-2)" NUAK1 "ARK5, KIAA0537" ENSG00000074590 "NUAK family kinase 1" O60285 12 106063345-106138954 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 152.5;Brain excitatory neurons: 85.0;Cardiomyocytes: 85.3;Microglia: 186.8;Oligodendrocytes: 95.6;Vascular endothelial cells: 255.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 255.7;Glial cells: 186.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 16914 "Astrocytes and Neuropil: 1243460.7;Microglia and Neuropil: 1821444.8;Neurons: 2009291.9" "Tissue enriched" "Detected in single" 26960 "cerebral cortex: 2696012.8" HPA057143 Supported "Nucleoplasm,Nucleoli fibrillar center,Microtubules,Mitotic spindle,Primary cilium" Yes No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 21 "Nucleoli fibrillar center" "Nucleoplasm, Microtubules, Mitotic spindle, Primary cilium" "HPA057143: " "unprognostic (2.45e-1)" "unprognostic (1.01e-1)" "unprognostic (3.92e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-2)" "unprognostic (1.10e-2)" "unprognostic (1.40e-1)" "unprognostic (3.45e-1)" "unprognostic (2.18e-1)" "unprognostic (1.30e-2)" "unprognostic (2.09e-3)" "unprognostic (6.09e-2)" "unprognostic (2.78e-1)" "unprognostic (9.92e-2)" "unprognostic (5.81e-2)" "unprognostic (8.72e-2)" "unprognostic (2.17e-3)" "unprognostic (1.03e-1)" "unprognostic (2.64e-1)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (9.57e-8)" "unprognostic (5.36e-1)" "unprognostic (2.19e-2)" "unprognostic (8.61e-2)" "unprognostic (1.69e-1)" "unprognostic (2.57e-3)" "unprognostic (3.40e-1)" "unprognostic (1.47e-2)" "unprognostic (7.63e-2)" "unprognostic (7.08e-2)" "unprognostic (3.89e-2)" NUAK2 "FLJ90349, SNARK" ENSG00000163545 "NUAK family kinase 2" Q9H093 1 205302063-205321745 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 37.5;esophagus: 55.1;vagina: 42.5" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 98.0;Epididymal efferent duct absorptive cells: 215.4;Epididymal efferent duct ciliated cells: 102.0;Esophageal apical cells: 561.1;Esophageal suprabasal cells: 104.6;Ocular epithelial cells: 129.3;Pancreatic duct cells: 143.6" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 561.1;Ductal cells: 215.4" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 18.2;ependymal cell: 10.6;leukocyte: 11.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 120.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Pancreas - Ductal cells, Skin - Keratinocyte (other), Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in single" 192 "Collecting ducts: 19220.4" "Tissue enriched" "Detected in single" 113 "salivary gland: 11259.5" HPA008958 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 5 "Nucleoplasm, Cytosol" "HPA008958: " "unprognostic (3.29e-1)" "unprognostic (7.45e-2)" "unprognostic (1.16e-1)" "unprognostic (1.47e-1)" "unprognostic (5.87e-2)" "unprognostic (7.23e-2)" "unprognostic (6.08e-3)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (7.99e-3)" "unprognostic (1.43e-2)" "unprognostic (5.44e-2)" "unprognostic (1.23e-1)" "unprognostic (2.36e-2)" "unprognostic (3.35e-2)" "unprognostic (5.75e-2)" "unprognostic (1.60e-3)" "unprognostic (8.96e-2)" "unprognostic (3.10e-2)" "unprognostic (5.72e-3)" "unprognostic (1.29e-1)" "unprognostic (4.68e-1)" "potential prognostic favorable (2.86e-5)" "unprognostic (5.50e-2)" "unprognostic (9.40e-2)" "unprognostic (3.46e-2)" "unprognostic (1.19e-1)" "unprognostic (3.14e-1)" "unprognostic (1.74e-1)" "unprognostic (1.43e-1)" "unprognostic (4.59e-3)" "unprognostic (1.58e-2)" NUB1 "BS4, NUB1L, NYREN18" ENSG00000013374 "Negative regulator of ubiquitin like proteins 1" Q9Y5A7 7 151341772-151378449 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 212.6;Late primary spermatocytes: 393.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 393.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2621201.6" "HPA021220, HPA050722, HPA053648" Approved Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 82: Dendritic cells - Antigen presentation" 19 "Nucleoplasm, Nucleoli" "HPA021220: , HPA050722: , HPA053648: " "potential prognostic favorable (3.79e-4)" "unprognostic (1.66e-1)" "unprognostic (8.20e-2)" "unprognostic (1.97e-1)" "unprognostic (1.54e-1)" "unprognostic (9.24e-2)" "unprognostic (1.47e-1)" "unprognostic (7.35e-3)" "unprognostic (7.18e-2)" "potential prognostic unfavorable (6.44e-4)" "potential prognostic favorable (7.41e-6)" "unprognostic (1.01e-2)" "unprognostic (7.07e-2)" "unprognostic (6.45e-3)" "unprognostic (1.58e-1)" "unprognostic (5.06e-3)" "unprognostic (1.41e-2)" "unprognostic (3.03e-1)" "unprognostic (2.51e-1)" "unprognostic (7.79e-2)" "unprognostic (1.37e-1)" "unprognostic (3.43e-2)" "unprognostic (9.38e-2)" "unprognostic (1.23e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-2)" "unprognostic (5.29e-1)" "unprognostic (1.51e-1)" "unprognostic (1.01e-1)" "unprognostic (1.23e-1)" "unprognostic (8.45e-3)" NUCKS1 NUCKS ENSG00000069275 "Nuclear casein kinase and cyclin dependent kinase substrate 1" Q9H1E3 1 205712822-205750182 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "kidney: 215346428.9;ovary: 247879881.9" "HPA062351, HPA063843" Supported Supported Nucleoplasm,Nucleoli No No 140000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 118 Nucleoplasm Nucleoli "HPA062351: , HPA063843: " "unprognostic (1.36e-1)" "unprognostic (1.51e-2)" "unprognostic (3.62e-1)" "unprognostic (1.02e-1)" "unprognostic (1.96e-2)" "unprognostic (9.99e-2)" "unprognostic (1.32e-1)" "unprognostic (3.27e-1)" "unprognostic (3.24e-1)" "unprognostic (3.28e-2)" "potential prognostic favorable (6.84e-6)" "unprognostic (1.77e-2)" "unprognostic (1.42e-2)" "unprognostic (4.33e-2)" "unprognostic (2.94e-3)" "unprognostic (2.42e-2)" "unprognostic (3.34e-3)" "unprognostic (9.72e-2)" "unprognostic (2.71e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (1.18e-3)" "unprognostic (3.41e-1)" "unprognostic (2.64e-1)" "unprognostic (1.05e-2)" "unprognostic (2.21e-2)" "unprognostic (7.97e-3)" "unprognostic (1.82e-2)" "unprognostic (2.78e-1)" "unprognostic (1.81e-2)" "unprognostic (2.57e-1)" NUDCD2 "DKFZp686E10109, NudCL2" ENSG00000170584 "NudC domain containing 2" Q8WVJ2 5 163446526-163460102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA037384, HPA037385" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA 18000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 97: Non-specific - Cellular respiration" 22 Microtubules "Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA037384: , HPA037385: " "unprognostic (4.84e-2)" "unprognostic (7.25e-2)" "unprognostic (1.51e-1)" "unprognostic (7.14e-2)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" "unprognostic (2.85e-2)" "unprognostic (2.12e-1)" "unprognostic (4.46e-3)" "potential prognostic unfavorable (5.97e-5)" "potential prognostic favorable (5.47e-6)" "unprognostic (2.81e-2)" "unprognostic (3.28e-1)" "unprognostic (8.75e-2)" "unprognostic (1.44e-2)" "unprognostic (5.04e-3)" "unprognostic (2.41e-2)" "unprognostic (3.23e-1)" "unprognostic (6.14e-2)" "unprognostic (3.25e-1)" "unprognostic (5.51e-2)" "unprognostic (2.35e-1)" "unprognostic (8.02e-2)" "unprognostic (1.66e-1)" "unprognostic (2.81e-3)" "unprognostic (4.86e-2)" "unprognostic (2.44e-1)" "unprognostic (1.35e-1)" "unprognostic (6.25e-2)" "unprognostic (5.20e-2)" "unprognostic (2.14e-1)" NUDT1 MTH1 ENSG00000106268 "Nudix hydrolase 1" P36639 7 2242226-2251146 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 114.2;Esophageal basal cells: 175.1;Hofbauer cells: 125.0;Late primary spermatocytes: 105.8;Late spermatids: 167.4;Megakaryocyte progenitors: 112.0;Megakaryocytes: 340.0;Monocyte progenitors: 123.0" "Cell type enhanced" "Detected in many" "Basal cells: 175.1;Megakaryocytes: 340.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Fibroblasts, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "bone marrow: 12088656.4" HPA012636 Approved Supported Cytosol No No 52000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 7 Cytosol "HPA012636: " "unprognostic (1.26e-1)" "unprognostic (3.80e-2)" "unprognostic (3.33e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (8.07e-5)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (9.91e-4)" "unprognostic (3.53e-1)" "unprognostic (2.27e-1)" "unprognostic (1.34e-3)" "validated prognostic unfavorable (3.45e-6)" "validated prognostic unfavorable (7.31e-6)" "unprognostic (1.27e-1)" "validated prognostic unfavorable (3.28e-4)" "validated prognostic unfavorable (8.07e-8)" "validated prognostic unfavorable (6.28e-4)" "validated prognostic unfavorable (6.07e-4)" "unprognostic (3.77e-2)" "unprognostic (5.14e-2)" "unprognostic (5.86e-2)" "unprognostic (5.03e-2)" "unprognostic (4.85e-2)" "unprognostic (1.21e-1)" "unprognostic (1.91e-1)" "unprognostic (1.08e-1)" "unprognostic (1.30e-1)" "unprognostic (7.92e-2)" "unprognostic (9.84e-2)" "unprognostic (8.85e-2)" "unprognostic (1.54e-2)" "unprognostic (9.13e-2)" NUDT14 UGPP ENSG00000183828 "Nudix hydrolase 14" O95848 14 105172938-105181323 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 58.8;Hofbauer cells: 51.1;Parietal cells: 38.9" "Cell type enhanced" "Detected in many" "Enterocytes: 58.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 13331288.7" "Low tissue specificity" "Detected in many" "HPA046755, HPA058759" Approved Approved Nucleoli,Microtubules NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 9 Microtubules Nucleoli "HPA046755: , HPA058759: " "unprognostic (5.50e-3)" "unprognostic (9.15e-3)" "unprognostic (8.26e-2)" "unprognostic (2.90e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "unprognostic (9.61e-2)" "unprognostic (4.18e-1)" "unprognostic (1.85e-1)" "unprognostic (1.56e-1)" "potential prognostic favorable (2.09e-4)" "unprognostic (2.61e-1)" "unprognostic (2.89e-2)" "unprognostic (8.58e-3)" "unprognostic (9.36e-3)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (2.30e-1)" "unprognostic (3.81e-2)" "unprognostic (3.04e-2)" "unprognostic (4.16e-2)" "unprognostic (1.93e-3)" "unprognostic (1.08e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.08e-1)" "unprognostic (1.88e-1)" "unprognostic (4.85e-3)" "unprognostic (9.34e-3)" NUDT15 "FLJ10956, MTH2" ENSG00000136159 "Nudix hydrolase 15" Q9NV35 13 48037726-48047221 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 84.9;Extravillous trophoblasts: 98.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 175393.9;Large ducts: 158048.4;Pancreatic islets: 275798.4" "Tissue enriched" "Detected in many" "Stomach: 85057896.3" "HPA038968, HPA038969" Approved Supported Nucleoplasm Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 16: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 1 Nucleoplasm "HPA038968: , HPA038969: " "unprognostic (2.43e-1)" "unprognostic (7.74e-3)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (1.50e-1)" "unprognostic (1.82e-1)" "unprognostic (7.11e-2)" "unprognostic (1.01e-1)" "unprognostic (2.15e-3)" "unprognostic (2.82e-3)" "potential prognostic favorable (5.56e-6)" "unprognostic (2.80e-3)" "unprognostic (4.24e-2)" "unprognostic (5.24e-3)" "potential prognostic unfavorable (4.35e-6)" "unprognostic (1.00e-3)" "unprognostic (3.74e-3)" "unprognostic (3.50e-1)" "unprognostic (8.29e-2)" "unprognostic (1.31e-1)" "unprognostic (9.84e-2)" "unprognostic (2.43e-2)" "unprognostic (1.00e-2)" "unprognostic (1.33e-1)" "unprognostic (2.67e-1)" "unprognostic (2.29e-1)" "potential prognostic unfavorable (9.20e-5)" "unprognostic (1.30e-1)" "unprognostic (3.72e-1)" "unprognostic (1.95e-1)" "unprognostic (2.32e-1)" NUDT16 FLJ31265 ENSG00000198585 "Nudix hydrolase 16" Q96DE0 3 131381671-131388830 "Enzymes, Predicted intracellular proteins" "Nucleotide metabolism" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 159.7;Enterocytes: 307.1;Hepatocytes: 113.5;Kupffer cells: 224.5" "Cell type enhanced" "Detected in all" "Enterocytes: 307.1;Mononuclear phagocytes: 224.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 41.7;eosinophil: 47.1;intermediate monocyte: 54.6;myeloid DC: 32.5;neutrophil: 34.1;non-classical monocyte: 63.7" "Group enriched" "Detected in all" 4 "dendritic cells: 32.5;granulocytes: 47.1;monocytes: 63.7" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA060452, HPA062492" Uncertain Supported Nucleoplasm,Nucleoli NA NA 27000 "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 4 "Nucleoplasm, Nucleoli" "HPA060452: , HPA062492: " "unprognostic (3.27e-1)" "unprognostic (5.50e-2)" "unprognostic (1.95e-2)" "unprognostic (4.40e-2)" "unprognostic (2.55e-1)" "unprognostic (3.94e-1)" "unprognostic (6.37e-2)" "potential prognostic unfavorable (4.35e-5)" "unprognostic (1.16e-1)" "unprognostic (7.11e-3)" "potential prognostic favorable (1.72e-4)" "unprognostic (2.44e-2)" "potential prognostic favorable (1.44e-4)" "potential prognostic unfavorable (5.21e-4)" "unprognostic (1.95e-3)" "unprognostic (3.88e-2)" "unprognostic (1.43e-1)" "unprognostic (2.77e-1)" "unprognostic (1.43e-2)" "unprognostic (2.22e-1)" "unprognostic (6.38e-3)" "unprognostic (1.99e-1)" "unprognostic (6.83e-2)" "unprognostic (2.32e-1)" "potential prognostic favorable (2.98e-4)" "unprognostic (1.03e-2)" "unprognostic (3.83e-2)" "unprognostic (7.38e-2)" "unprognostic (3.82e-1)" "unprognostic (5.52e-3)" "unprognostic (2.16e-1)" NUDT2 APAH1 ENSG00000164978 "Nudix hydrolase 2" P50583 9 34329506-34343711 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Disease variant, Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB004684, HPA044903, HPA058623, HPA067639" Uncertain Approved Nucleoplasm NA NA 27000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 3 Nucleoplasm "CAB004684: , HPA044903: , HPA058623: , HPA067639: " "unprognostic (2.16e-1)" "unprognostic (1.01e-1)" "unprognostic (2.13e-1)" "unprognostic (1.37e-1)" "unprognostic (1.25e-1)" "unprognostic (5.83e-2)" "unprognostic (8.47e-2)" "unprognostic (5.31e-2)" "unprognostic (1.58e-1)" "unprognostic (3.10e-2)" "potential prognostic favorable (1.33e-4)" "unprognostic (1.99e-2)" "unprognostic (9.10e-2)" "unprognostic (7.63e-2)" "unprognostic (4.67e-2)" "unprognostic (1.48e-2)" "unprognostic (4.50e-2)" "unprognostic (6.45e-2)" "unprognostic (6.07e-3)" "unprognostic (1.36e-1)" "unprognostic (3.32e-1)" "unprognostic (3.31e-3)" "unprognostic (1.94e-1)" "unprognostic (7.62e-2)" "unprognostic (1.07e-1)" "unprognostic (1.96e-1)" "unprognostic (3.68e-2)" "unprognostic (1.08e-2)" "unprognostic (2.83e-1)" "unprognostic (1.38e-1)" "unprognostic (2.25e-3)" NUDT22 MGC13045 ENSG00000149761 "Nudix hydrolase 22" Q9BRQ3 11 64225941-64230686 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 133.3;Esophageal apical cells: 126.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 87584.4;Large ducts: 48406.9;Microglia and Neuropil: 68186.1" "Not detected" "Not detected" "HPA039334, HPA053464" Approved Enhanced Nucleoplasm No No "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 17 Nucleoplasm "HPA039334: , HPA053464: " "unprognostic (1.18e-3)" "unprognostic (1.15e-1)" "unprognostic (2.16e-2)" "unprognostic (5.90e-2)" "unprognostic (3.09e-2)" "unprognostic (3.42e-2)" "unprognostic (2.56e-2)" "unprognostic (3.47e-1)" "unprognostic (1.61e-2)" "unprognostic (1.66e-2)" "unprognostic (3.99e-1)" "unprognostic (5.08e-2)" "potential prognostic favorable (4.23e-5)" "unprognostic (4.00e-3)" "unprognostic (1.47e-1)" "unprognostic (1.73e-1)" "unprognostic (7.16e-2)" "unprognostic (2.67e-1)" "unprognostic (1.77e-1)" "unprognostic (2.45e-1)" "unprognostic (2.37e-1)" "unprognostic (1.20e-1)" "unprognostic (4.84e-2)" "unprognostic (1.90e-2)" "unprognostic (4.26e-2)" "unprognostic (2.96e-1)" "unprognostic (6.05e-2)" "unprognostic (3.87e-2)" "unprognostic (1.72e-1)" "unprognostic (7.90e-2)" "unprognostic (9.63e-3)" NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422573-87459455 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" Enzyme NA NA 42000 "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 5 "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: , HPA044866: , HPA078535: " "unprognostic (1.29e-1)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.95e-3)" "potential prognostic favorable (4.43e-4)" "unprognostic (1.24e-1)" "unprognostic (1.25e-1)" "unprognostic (6.98e-2)" "unprognostic (1.83e-2)" "unprognostic (5.60e-2)" "validated prognostic favorable (2.89e-9)" "validated prognostic favorable (4.98e-4)" "unprognostic (5.50e-3)" "unprognostic (5.61e-2)" "unprognostic (4.00e-3)" "unprognostic (1.23e-1)" "unprognostic (1.94e-1)" "unprognostic (5.59e-2)" "unprognostic (1.36e-1)" "unprognostic (3.96e-2)" "unprognostic (3.37e-2)" "unprognostic (3.20e-1)" "unprognostic (9.64e-3)" "unprognostic (4.85e-1)" "unprognostic (1.90e-2)" "unprognostic (1.13e-1)" "unprognostic (5.15e-2)" "unprognostic (7.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (8.21e-2)" NUF2 "CDCA1, CT106, NUF2R" ENSG00000143228 "NUF2 component of NDC80 kinetochore complex" Q9BZD4 1 163266576-163355764 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 26.8;lymphoid tissue: 24.2;testis: 50.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 194.3;Differentiating spermatogonia: 64.4;Early primary spermatocytes: 159.2;Epicardial cells: 113.7;Erythrocyte progenitors: 86.3;Late primary spermatocytes: 308.2;Monocyte progenitors: 89.6;Oocytes: 82.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 113.7;Myocytes: 194.3;Spermatogenic cell types: 308.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 4.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Granulosa cells: 2441088.3;Neutrophils: 986171.3" "Tissue enriched" "Detected in single" 727 "bone marrow: 72715.1" "HPA059692, HPA076604" Supported Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 44 Nucleoplasm "Kinetochore, Cytosol" "HPA059692: , HPA076604: " "unprognostic (4.21e-2)" "unprognostic (9.25e-2)" "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (2.59e-1)" "unprognostic (6.94e-2)" "unprognostic (4.23e-2)" "unprognostic (2.08e-3)" "unprognostic (2.33e-2)" "validated prognostic unfavorable (5.80e-13)" "validated prognostic unfavorable (7.05e-6)" "potential prognostic unfavorable (1.54e-8)" "validated prognostic unfavorable (2.44e-6)" "validated prognostic unfavorable (1.81e-6)" "potential prognostic unfavorable (7.33e-5)" "unprognostic (8.24e-3)" "unprognostic (3.69e-2)" "unprognostic (3.22e-2)" "unprognostic (3.91e-1)" "unprognostic (8.65e-2)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (5.05e-4)" "unprognostic (3.79e-2)" "unprognostic (3.81e-1)" "unprognostic (1.17e-1)" "unprognostic (5.40e-3)" "unprognostic (8.31e-2)" "unprognostic (6.41e-2)" "unprognostic (1.03e-2)" NUFIP1 "NUFIP, Rsa1" ENSG00000083635 "Nuclear FMR1 interacting protein 1" Q9UHK0 13 44939249-44989471 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 110.9;Oocytes: 69.1" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 110.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA029958, HPA029959" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 18: Non-specific - Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 26 Nucleoplasm Nucleoli "HPA029958: , HPA029959: " "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "unprognostic (5.57e-2)" "unprognostic (3.03e-3)" "unprognostic (9.61e-2)" "unprognostic (8.37e-2)" "unprognostic (6.38e-2)" "unprognostic (2.12e-2)" "unprognostic (9.03e-3)" "potential prognostic unfavorable (7.62e-5)" "potential prognostic favorable (1.41e-5)" "unprognostic (2.38e-2)" "unprognostic (3.74e-1)" "unprognostic (7.01e-2)" "potential prognostic unfavorable (6.71e-4)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (3.78e-2)" "unprognostic (6.02e-2)" "unprognostic (2.69e-3)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (3.50e-2)" "unprognostic (8.38e-2)" "unprognostic (2.09e-2)" "unprognostic (6.86e-2)" "unprognostic (9.41e-2)" "unprognostic (8.68e-3)" "unprognostic (2.22e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.48e-2)" NUP188 KIAA0169 ENSG00000095319 "Nucleoporin 188" Q5SRE5 9 128947699-129007096 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Cataract, Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 81.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 20986652.9" "Tissue enhanced" "Detected in many" "skin: 1735976.4;Stomach: 1287472.4" "HPA061750, HPA063942" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No 6700 "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 25: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 103: Non-specific - Basic cellular processes" 15 Nucleoplasm "Nucleoli, Cytosol" "HPA061750: , HPA063942: " "unprognostic (8.42e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-1)" "unprognostic (6.50e-2)" "unprognostic (7.76e-2)" "unprognostic (2.05e-2)" "unprognostic (1.09e-1)" "unprognostic (1.53e-2)" "unprognostic (7.68e-2)" "unprognostic (2.65e-3)" "potential prognostic favorable (6.59e-4)" "unprognostic (5.04e-3)" "unprognostic (3.29e-1)" "potential prognostic unfavorable (9.41e-4)" "unprognostic (3.99e-2)" "unprognostic (4.49e-2)" "potential prognostic unfavorable (2.62e-5)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (6.23e-2)" "unprognostic (5.76e-2)" "unprognostic (1.48e-1)" "unprognostic (4.44e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-1)" "unprognostic (9.19e-3)" "unprognostic (1.08e-1)" "unprognostic (1.08e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-3)" "unprognostic (5.35e-2)" NUP210L ENSG00000143552 "Nucleoporin 210 like" Q5VU65 1 153992690-154155116 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 41 "testis: 24.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 56.0;Early primary spermatocytes: 107.5;Endometrial luminal cells: 82.8;Late primary spermatocytes: 54.8" "Cell type enhanced" "Detected in many" "Luminal cells: 82.8;Spermatogenic cell types: 107.5" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 21993 "Skeletal myofibers: 2199276.7" "Not detected" "Not detected" "HPA047195, HPA064245, HPA066707" Enhanced Approved "Nuclear bodies,Cytosol" No No "Cluster 57: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Nuclear bodies" Cytosol "HPA047195: , HPA064245: , HPA066707: " NUP35 MP44 ENSG00000163002 "Nucleoporin 35" Q8NFH5 2 183117513-183161680 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 207.4;Late spermatids: 769.3" "Cell type enriched" "Detected in all" 7 "Spermatogenic cell types: 769.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 3804795.5" "Low tissue specificity" "Detected in many" "HPA018401, HPA018410, HPA018441" Enhanced Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 45 "Nucleoplasm, Nuclear membrane" "Plasma membrane" "HPA018401: , HPA018410: , HPA018441: " "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (1.87e-1)" "unprognostic (2.13e-1)" "unprognostic (2.48e-1)" "unprognostic (5.58e-2)" "unprognostic (1.01e-1)" "unprognostic (9.93e-3)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (5.70e-5)" "potential prognostic favorable (3.54e-4)" "unprognostic (2.81e-2)" "unprognostic (1.11e-2)" "unprognostic (4.70e-3)" "potential prognostic unfavorable (9.05e-4)" "unprognostic (4.99e-3)" "unprognostic (1.87e-2)" "unprognostic (4.77e-2)" "unprognostic (7.43e-2)" "unprognostic (2.01e-2)" "unprognostic (1.71e-1)" "unprognostic (1.40e-2)" "unprognostic (5.70e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (9.87e-2)" "unprognostic (1.08e-2)" "unprognostic (3.22e-2)" "unprognostic (1.22e-1)" "unprognostic (1.37e-1)" "unprognostic (2.51e-1)" "unprognostic (2.60e-1)" NUP42 "CG1, H_RG271G13.9, hCG1, NLP_1, NUPL2" ENSG00000136243 "Nucleoporin 42" O15504 7 23181841-23201011 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 332.6;Late primary spermatocytes: 201.5;Oligodendrocyte progenitor cells: 215.9" "Cell type enhanced" "Detected in all" "Glial cells: 215.9;Spermatogenic cell types: 332.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 766220.6" "Tissue enhanced" "Detected in many" "Stomach: 1425152.9" HPA058084 Supported "Nucleoplasm,Nuclear membrane,Cytosol" NA No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 21 "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA058084: " "unprognostic (5.60e-2)" "unprognostic (4.97e-2)" "unprognostic (4.20e-1)" "unprognostic (7.60e-2)" "unprognostic (4.05e-2)" "unprognostic (1.50e-1)" "unprognostic (8.30e-2)" "unprognostic (3.72e-1)" "unprognostic (1.92e-3)" "unprognostic (4.03e-3)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (6.94e-5)" "unprognostic (4.25e-3)" "unprognostic (1.25e-1)" "unprognostic (7.27e-2)" "unprognostic (1.13e-1)" "unprognostic (4.07e-2)" "unprognostic (8.41e-2)" "unprognostic (2.99e-2)" "unprognostic (4.06e-3)" "unprognostic (2.01e-2)" "unprognostic (3.88e-2)" "unprognostic (9.63e-3)" "unprognostic (3.27e-2)" "unprognostic (1.23e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-3)" "unprognostic (2.60e-2)" NUP85 "FLJ12549, NUP75" ENSG00000125450 "Nucleoporin 85" Q9BW27 17 75205659-75235758 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 119.7" "Cell type enhanced" "Detected in all" "Oocytes: 119.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA061910, HPA062595" Supported Supported "Nucleoplasm,Vesicles,Actin filaments,Basal body,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 40 Nucleoplasm "Vesicles, Actin filaments, Basal body, Cytosol" "HPA061910: , HPA062595: " "unprognostic (5.68e-3)" "unprognostic (8.04e-2)" "unprognostic (3.23e-2)" "unprognostic (1.75e-1)" "unprognostic (2.88e-3)" "unprognostic (1.14e-1)" "unprognostic (1.71e-1)" "unprognostic (1.23e-2)" "unprognostic (2.67e-1)" "unprognostic (2.14e-2)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (6.10e-2)" "unprognostic (5.74e-2)" "validated prognostic unfavorable (5.16e-7)" "validated prognostic unfavorable (7.96e-4)" "unprognostic (1.54e-3)" "potential prognostic unfavorable (4.73e-5)" "unprognostic (5.85e-2)" "unprognostic (5.19e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-3)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (2.49e-2)" "unprognostic (2.44e-2)" "unprognostic (6.28e-3)" "unprognostic (9.00e-2)" "unprognostic (4.08e-3)" "unprognostic (4.93e-2)" "unprognostic (3.73e-2)" "unprognostic (3.63e-1)" NUSAP1 "ANKT, BM037, FLJ13421, LNP, PRO0310p1, Q0310, SAPL" ENSG00000137804 "Nucleolar and spindle associated protein 1" Q9BXS6 15 41320794-41381050 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 83.5;lymphoid tissue: 94.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 5.0;Enteric transient amplifying cells: 17.9;Erythrocyte progenitors: 12.0;Extravillous trophoblasts: 9.2;Foveolar cells: 5.2;Gastric progenitor cells: 7.7;Hofbauer cells: 4.6;Migrating cytotrophoblasts: 5.2;Monocyte progenitors: 12.1;Oocytes: 4.6;Paneth cells: 11.6;Proximal tubule cells: 6.2" "Cell type enhanced" "Detected in many" "Erythrocytes: 12.0;Mononuclear phagocytes: 12.1;Proliferating cells: 17.9;Secretory gland support: 11.6;Trophoblast cells: 9.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 14 "basophil: 10.5;T-reg: 7.7" "Group enriched" "Detected in many" 14 "granulocytes: 10.5;T-cells: 7.7" "Low cancer specificity" "Detected in all" "Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 22856 "Granulosa cells: 4011426.2;Neutrophils: 1580318.5;T-cells: 1265142.1" "Tissue enriched" "Detected in single" 31237 "bone marrow: 3123695.6" "HPA042904, HPA074847" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" Yes Yes "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 14 "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA042904: , HPA074847: " "unprognostic (2.26e-1)" "unprognostic (6.47e-2)" "unprognostic (7.71e-2)" "unprognostic (4.36e-2)" "unprognostic (1.89e-1)" "unprognostic (5.96e-2)" "unprognostic (8.26e-2)" "unprognostic (6.89e-3)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (2.21e-4)" "validated prognostic unfavorable (7.02e-8)" "validated prognostic unfavorable (1.24e-4)" "potential prognostic unfavorable (4.07e-12)" "validated prognostic unfavorable (4.10e-4)" "validated prognostic unfavorable (1.96e-7)" "validated prognostic unfavorable (3.24e-5)" "validated prognostic unfavorable (1.13e-4)" "unprognostic (3.75e-2)" "unprognostic (2.46e-2)" "unprognostic (5.47e-2)" "unprognostic (5.95e-2)" "potential prognostic unfavorable (4.12e-4)" "unprognostic (8.19e-3)" "unprognostic (1.87e-2)" "unprognostic (3.16e-1)" "unprognostic (1.70e-1)" "unprognostic (9.36e-3)" "unprognostic (1.15e-2)" "unprognostic (5.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.21e-1)" NXNL2 "C9orf121, RdCVF2" ENSG00000130045 "Nucleoredoxin like 2" Q5VZ03 9 88534033-88584274 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "cervix: 9.6;fallopian tube: 14.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 22.8;Early spermatids: 23.5;Endometrial ciliated cells: 63.4;Endometrial glandular cells: 23.6;Endometrial luminal cells: 23.9;Endometrial secretory cells: 43.4;Ependymal cells: 22.7;Epididymal efferent duct absorptive cells: 78.1;Epididymal efferent duct ciliated cells: 44.9;Fallopian secretory cells: 79.6;Fallopian tube ciliated cells: 58.8;Pituitary stem cells: 23.1;Proximal tubule cells: 32.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 63.4;Ductal cells: 78.1;Secretory cells: 79.6" "Cell type enhanced" "Detected in many" "ependymal cell: 22.6" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 7.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Stomach - Fibroblasts, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Fallopian tube cells: 226557.3" "Tissue enriched" "Detected in single" 74 "fallopian tube: 7434.2" HPA045526 Uncertain Approved Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Cytosol "HPA045526: " "unprognostic (2.88e-3)" "unprognostic (7.45e-3)" "unprognostic (1.07e-2)" "unprognostic (8.83e-2)" "potential prognostic favorable (3.41e-5)" "unprognostic (3.41e-1)" "unprognostic (9.39e-3)" "unprognostic (1.22e-1)" "unprognostic (8.96e-3)" "unprognostic (2.03e-1)" "unprognostic (7.93e-2)" "unprognostic (1.66e-2)" "unprognostic (1.31e-1)" "unprognostic (3.15e-1)" "unprognostic (3.69e-2)" NYAP2 KIAA1486 ENSG00000144460 "Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 2" Q9P242 2 225399710-225729887 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.6;retina: 3.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 138.0;Brain inhibitory neurons: 314.6;Corticotrophs: 207.8;Gonadotrophs: 154.1;Lactotrophs: 155.4;Myonuclei: 88.2;Other brain neurons: 200.3;Retinal amacrine cells: 74.7;Retinal bipolar cells: 554.9;Somatotrophs: 108.4;Thyrotrophs: 197.6" "Group enriched" "Detected in many" 4 "Neuronal cells: 554.9;Pituitary endocrine cells: 207.8" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 1450.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 826 "Microglia and Neuropil: 41434.7;Neurons: 123800.9" "Tissue enriched" "Detected in single" 17213 "cerebral cortex: 1721261.6" HPA045531 Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 6 "Microtubules, Primary cilium, Cytosol" "Nucleoplasm, Cytokinetic bridge, Mitotic spindle, Basal body" "HPA045531: " "unprognostic (6.23e-3)" OAS3 ENSG00000111331 "2'-5'-oligoadenylate synthetase 3" Q9Y6K5 12 112938051-112976460 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 26.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 64.1;Esophageal basal cells: 32.9;Esophageal suprabasal cells: 38.4;Extravillous trophoblasts: 35.9;Foveolar cells: 46.2;Ocular epithelial cells: 35.5;Urothelial cells: 56.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 64.1;Barrier epithelial cells: 56.4" "Cell type enriched" "Detected in many" 4 "endothelial cell: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 15.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Macrophages: 29230819.9;T-cells: 19202429.4" "Group enriched" "Detected in many" "intestine: 31471240.5;lymphoid tissue: 25987914.3" "HPA041253, HPA041372" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 18 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041253: , HPA041372: " "unprognostic (9.88e-2)" "unprognostic (1.29e-1)" "unprognostic (3.44e-2)" "unprognostic (1.39e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.78e-2)" "unprognostic (1.25e-1)" "unprognostic (3.32e-1)" "unprognostic (1.13e-3)" "unprognostic (2.11e-1)" "unprognostic (1.17e-1)" "unprognostic (5.84e-2)" "unprognostic (1.53e-2)" "unprognostic (1.73e-2)" "unprognostic (3.43e-2)" "unprognostic (3.30e-2)" "unprognostic (1.27e-1)" "unprognostic (3.95e-1)" "unprognostic (1.86e-1)" "potential prognostic unfavorable (6.47e-5)" "unprognostic (3.06e-3)" "unprognostic (9.59e-2)" "unprognostic (3.68e-2)" "unprognostic (5.76e-3)" "unprognostic (2.17e-2)" "unprognostic (8.94e-2)" "unprognostic (7.91e-2)" "unprognostic (4.32e-2)" "unprognostic (2.54e-2)" OAT HOGA ENSG00000065154 "Ornithine aminotransferase" P04181 10 124397303-124418976 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Aminotransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 736.4" "Cell type enhanced" "Detected in all" "Breast lactating cells: 381.4;Enterocytes: 1241.2;Respiratory deuterosomal cells: 377.3" "Cell type enhanced" "Detected in all" "Enterocytes: 1241.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubules: 112519918.7" "Tissue enriched" "Detected in all" "intestine: 184351443.4" "CAB033576, HPA040098, HPA064742" Enhanced Supported Nucleoplasm,Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 1: Enterocytes - Absorption and Digestion" 20 Mitochondria Nucleoplasm "CAB033576: , HPA040098: , HPA064742: " "unprognostic (8.28e-2)" "unprognostic (1.01e-2)" "unprognostic (6.11e-2)" "unprognostic (3.40e-2)" "unprognostic (1.43e-1)" "unprognostic (1.64e-1)" "unprognostic (2.09e-1)" "unprognostic (1.03e-2)" "unprognostic (1.13e-1)" "unprognostic (2.15e-1)" "potential prognostic favorable (3.63e-6)" "unprognostic (7.76e-2)" "unprognostic (1.58e-1)" "unprognostic (2.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.61e-2)" "unprognostic (2.03e-1)" "unprognostic (1.29e-1)" "unprognostic (3.34e-2)" "unprognostic (2.62e-3)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (1.85e-1)" "unprognostic (1.02e-1)" "unprognostic (8.04e-2)" "unprognostic (4.21e-1)" "unprognostic (2.14e-1)" "unprognostic (4.05e-1)" "unprognostic (9.14e-2)" "unprognostic (1.78e-1)" "unprognostic (4.60e-2)" "unprognostic (2.11e-2)" OAZ3 ENSG00000143450 "Ornithine decarboxylase antizyme 3" Q9UMX2 1 151762899-151771334 "Predicted intracellular proteins" "Polyamine biosynthesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "testis: 224.4" "Cell type enriched" "Detected in many" 7 "Late spermatids: 21908.7" "Cell type enriched" "Detected in many" 329 "Spermatogenic cell types: 21908.7" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 31.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030136, HPA045808" Supported "Nucleoplasm,Mid piece,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 45: Non-specific - Nuclear processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 12 Nucleoplasm "Mid piece, Principal piece" "HPA030136: , HPA045808: " "unprognostic (2.41e-1)" "unprognostic (1.24e-1)" "unprognostic (2.43e-1)" "unprognostic (2.61e-3)" "unprognostic (2.48e-1)" "unprognostic (1.05e-1)" "unprognostic (4.68e-2)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (3.30e-4)" "unprognostic (3.65e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (4.91e-3)" "unprognostic (8.62e-3)" "unprognostic (2.02e-1)" "unprognostic (3.56e-1)" "unprognostic (6.44e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (8.55e-6)" "unprognostic (3.08e-2)" "unprognostic (3.04e-1)" "unprognostic (5.60e-1)" "unprognostic (3.10e-3)" "unprognostic (3.85e-1)" "unprognostic (4.61e-2)" "unprognostic (3.84e-1)" "unprognostic (1.91e-1)" "unprognostic (1.90e-1)" "unprognostic (1.58e-1)" OCIAD2 MGC45416 ENSG00000145247 "OCIA domain containing 2" Q56VL3 4 48885019-48906937 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 144.9" "Cell type enhanced" "Detected in many" "Colonocytes: 325.6;Enterocytes: 634.3;Epididymal efferent duct absorptive cells: 616.6;Gastric chief cells: 314.5;Gastric progenitor cells: 483.2" "Cell type enhanced" "Detected in many" "Ductal cells: 616.6;Enterocytes: 634.3;Proliferating cells: 483.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Proximal tubules: 16638743.7" "Tissue enhanced" "Detected in many" "kidney: 4196093.8" "HPA040979, HPA041090" Enhanced Enhanced Mitochondria No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 2 Mitochondria "HPA040979: , HPA041090: " "unprognostic (1.68e-1)" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (9.91e-2)" "unprognostic (5.14e-2)" "unprognostic (9.29e-2)" "unprognostic (1.71e-2)" "unprognostic (1.82e-3)" "unprognostic (2.28e-2)" "unprognostic (4.70e-2)" "potential prognostic favorable (2.01e-6)" "unprognostic (4.03e-3)" "potential prognostic favorable (2.26e-6)" "unprognostic (7.37e-2)" "potential prognostic favorable (3.40e-4)" "unprognostic (2.79e-3)" "unprognostic (3.11e-3)" "unprognostic (8.99e-2)" "unprognostic (4.01e-2)" "unprognostic (1.14e-2)" "unprognostic (8.46e-2)" "unprognostic (1.35e-2)" "unprognostic (2.80e-1)" "unprognostic (4.70e-2)" "unprognostic (9.16e-3)" "unprognostic (1.13e-1)" "unprognostic (2.03e-1)" "unprognostic (1.99e-1)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "unprognostic (9.79e-2)" OCRL "Dent-2, OCRL1" ENSG00000122126 "OCRL inositol polyphosphate-5-phosphatase" Q01968 X 129539849-129592561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Lipid metabolism" Hydrolase "Cataract, Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 97.3;Sertoli cells: 88.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 1.0;intermediate monocyte: 1.1;myeloid DC: 1.2;non-classical monocyte: 3.7" "Group enriched" "Detected in many" 8 "dendritic cells: 1.2;monocytes: 3.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "cerebral cortex: 18775425.3" HPA012495 Approved Approved "Microtubules,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 65: Brain - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 18: Adrenal cortex cells - Steroidogensis" 42 "Microtubules, Primary cilium" "Centriolar satellite, Basal body, Cytosol" "HPA012495: " "unprognostic (8.08e-3)" "potential prognostic unfavorable (2.08e-6)" "unprognostic (6.32e-2)" "unprognostic (1.95e-2)" "unprognostic (3.15e-2)" "unprognostic (3.42e-1)" "unprognostic (5.30e-2)" "potential prognostic favorable (6.08e-5)" "unprognostic (1.53e-1)" "unprognostic (2.23e-1)" "potential prognostic favorable (1.14e-5)" "unprognostic (1.29e-1)" "unprognostic (2.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.16e-1)" "unprognostic (3.98e-2)" "unprognostic (1.98e-2)" "unprognostic (1.73e-1)" "unprognostic (2.28e-1)" "unprognostic (1.98e-2)" "unprognostic (1.60e-1)" "unprognostic (3.98e-1)" "unprognostic (3.60e-1)" "unprognostic (3.11e-1)" "unprognostic (1.52e-3)" "unprognostic (1.80e-1)" "unprognostic (2.82e-2)" "unprognostic (2.15e-1)" "unprognostic (3.01e-1)" "unprognostic (5.91e-2)" "unprognostic (4.83e-3)" ODAD2 "ARMC4, CILD23, DKFZP434P1735, FLJ10376, FLJ10817, gudu" ENSG00000169126 "Outer dynein arm docking complex subunit 2" Q5T2S8 10 27775186-27999079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 21.8;testis: 38.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 183.9;Early spermatids: 399.1;Endometrial ciliated cells: 204.4;Ependymal cells: 572.7;Epididymal efferent duct ciliated cells: 182.2;Fallopian tube ciliated cells: 353.1;Gonadotrophs: 211.7;Late primary spermatocytes: 352.9;Respiratory ciliated cells: 653.3" "Group enriched" "Detected in many" 6 "Ciliated cells: 653.3;Pituitary endocrine cells: 211.7;Spermatogenic cell types: 399.1" "Group enriched" "Detected in many" 20 "choroid plexus epithelial cell: 188.9;ependymal cell: 624.0" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 4.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 7.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 116907 "Fallopian tube cells: 11690670.0" "Tissue enriched" "Detected in single" 96930 "fallopian tube: 9692998.9" HPA037829 Enhanced Approved "Acrosome,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" 11 "End piece" "Acrosome, Principal piece" "HPA037829: " "unprognostic (4.67e-1)" "unprognostic (1.20e-1)" "unprognostic (3.54e-2)" "unprognostic (1.60e-1)" "unprognostic (1.79e-1)" "unprognostic (1.47e-2)" "unprognostic (1.40e-1)" "unprognostic (6.23e-2)" "unprognostic (5.85e-2)" "unprognostic (2.19e-2)" ODAD4 "DKFZP434H0115, TTC25" ENSG00000204815 "Outer dynein arm docking complex subunit 4" Q96NG3 17 41930617-41966503 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "choroid plexus: 11.5;fallopian tube: 16.0;testis: 22.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 77.8;Early spermatids: 214.6;Endometrial ciliated cells: 97.9;Ependymal cells: 109.8;Epididymal efferent duct ciliated cells: 109.1;Fallopian tube ciliated cells: 195.2;Late primary spermatocytes: 307.9;Respiratory ciliated cells: 268.9" "Group enriched" "Detected in many" 8 "Ciliated cells: 268.9;Spermatogenic cell types: 307.9" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 66.8;ependymal cell: 112.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 30388613.5" "Tissue enriched" "Detected in single" 196334 "fallopian tube: 19633432.0" HPA023908 Enhanced Uncertain "Centrosome,Basal body,Acrosome,Mid piece,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 47: Leukemia - Hemostasis" "Cluster 107: Ciliated cells - Cilia assembly & function" 7 "Centrosome, Basal body" "Acrosome, Mid piece, Principal piece, End piece" "HPA023908: " "unprognostic (5.29e-2)" "unprognostic (8.55e-2)" "unprognostic (4.53e-2)" "potential prognostic favorable (1.41e-4)" "unprognostic (4.79e-2)" "unprognostic (8.42e-2)" "unprognostic (1.74e-2)" "unprognostic (2.41e-1)" "unprognostic (2.34e-2)" "unprognostic (2.42e-3)" "unprognostic (7.88e-2)" "unprognostic (1.64e-1)" "unprognostic (1.45e-1)" ODF2 "CT134, ODF84" ENSG00000136811 "Outer dense fiber of sperm tails 2" Q5BJF6 9 128455186-128501292 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 8 "testis: 292.3" "Cell type enriched" "Detected in many" 5 "Late spermatids: 13180.6" "Cell type enriched" "Detected in all" 110 "Spermatogenic cell types: 13180.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Somatotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 28948224.0" "Group enriched" "Detected in many" "fallopian tube: 3578416.9;kidney: 10103626.5" "HPA001874, HPA048841" Enhanced Supported "Vesicles,Microtubules,Primary cilium,Centrosome,Basal body,Calyx,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 47: Testis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 11 "Primary cilium, Centrosome, Basal body, Connecting piece" "Vesicles, Microtubules, Calyx, Mid piece, Principal piece" "HPA001874: , HPA048841: " "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (4.50e-2)" "unprognostic (1.39e-1)" "unprognostic (1.22e-2)" "unprognostic (3.17e-1)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-1)" "unprognostic (1.60e-3)" "unprognostic (1.85e-2)" "unprognostic (2.31e-1)" "unprognostic (1.93e-3)" "unprognostic (2.54e-2)" "unprognostic (2.59e-2)" "unprognostic (3.75e-3)" "unprognostic (2.05e-1)" "unprognostic (3.77e-2)" "unprognostic (4.00e-1)" "unprognostic (8.84e-2)" "unprognostic (4.17e-2)" "unprognostic (7.22e-2)" "unprognostic (8.45e-3)" "unprognostic (1.14e-1)" "unprognostic (6.62e-2)" "unprognostic (4.18e-2)" "unprognostic (2.09e-2)" "unprognostic (4.34e-2)" "unprognostic (1.30e-1)" "unprognostic (1.94e-2)" ODF4 "CT136, OPPO1" ENSG00000184650 "Outer dense fiber of sperm tails 4" Q2M2E3 17 8339840-8346048 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 124 "testis: 12.3" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 9.5;Early spermatids: 28.5;Esophageal apical cells: 13.6;Late primary spermatocytes: 115.4;Late spermatids: 46.0" "Cell type enriched" "Detected in some" 8 "Spermatogenic cell types: 115.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA072129 Enhanced Approved "Principal piece" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 20 "Principal piece" "HPA072129: " OGDH "E1k, KGD1, OGDC-E1, OGDH2" ENSG00000105953 "Oxoglutarate dehydrogenase" Q02218 7 44606572-44709066 "Citric acid cycle related proteins, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 302.2;skeletal muscle: 340.6;tongue: 349.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 398.8;Neutrophils: 393.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1295422916.3" "Tissue enhanced" "Detected in all" "heart muscle: 707934515.3" "HPA019514, HPA020347" Supported Enhanced Mitochondria No No 91000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 44: Non-specific - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 19 Mitochondria "HPA019514: , HPA020347: " "unprognostic (1.89e-1)" "unprognostic (2.15e-2)" "unprognostic (1.76e-1)" "unprognostic (9.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.99e-2)" "unprognostic (2.21e-2)" "unprognostic (6.14e-3)" "unprognostic (6.85e-2)" "unprognostic (5.28e-2)" "potential prognostic favorable (3.38e-11)" "unprognostic (1.66e-2)" "potential prognostic favorable (8.90e-4)" "unprognostic (2.07e-1)" "unprognostic (3.01e-3)" "unprognostic (7.95e-2)" "unprognostic (2.27e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" "unprognostic (1.97e-2)" "unprognostic (2.45e-1)" "unprognostic (5.84e-2)" "unprognostic (1.93e-1)" "unprognostic (1.27e-1)" "unprognostic (1.22e-1)" "unprognostic (7.14e-2)" "unprognostic (1.09e-1)" "unprognostic (1.98e-1)" "unprognostic (5.95e-2)" "unprognostic (4.41e-2)" "unprognostic (6.41e-2)" OGFOD1 "FLJ10826, KIAA1612, TPA1" ENSG00000087263 "2-oxoglutarate and iron dependent oxygenase domain containing 1" Q8N543 16 56451521-56479104 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 181.9" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 181.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 682745.9;T-cells: 357984.1" "Tissue enriched" "Detected in some" "lymphoid tissue: 87584.2" "HPA003215, HPA003722" Approved Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 5 Nucleoplasm Cytosol "HPA003215: , HPA003722: " "unprognostic (1.66e-1)" "unprognostic (2.88e-2)" "unprognostic (2.70e-1)" "unprognostic (5.47e-3)" "unprognostic (2.97e-1)" "unprognostic (1.36e-1)" "unprognostic (5.01e-2)" "unprognostic (1.34e-1)" "unprognostic (1.69e-2)" "unprognostic (1.08e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.98e-1)" "potential prognostic unfavorable (5.34e-5)" "unprognostic (3.32e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (9.23e-2)" "unprognostic (6.57e-2)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" "unprognostic (1.74e-2)" "unprognostic (1.64e-2)" "unprognostic (8.79e-2)" "unprognostic (1.09e-1)" "unprognostic (8.41e-2)" "unprognostic (5.28e-2)" "unprognostic (1.41e-1)" "unprognostic (5.66e-2)" "unprognostic (2.97e-2)" "unprognostic (1.03e-2)" OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533087-71575892 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia and Neuropil: 52147664.5;Neurons: 68812385.9" "Tissue enriched" "Detected in many" "cerebral cortex: 44017520.6" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Yes No 3600 "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 9: T-cells - Adaptive immunity: Regulation" 124 Nucleoplasm "Plasma membrane" "CAB034099: , HPA030751: , HPA030752: , HPA030753: , HPA030754: " "potential prognostic favorable (4.12e-4)" "unprognostic (9.34e-3)" "unprognostic (1.25e-1)" "unprognostic (9.57e-2)" "unprognostic (6.48e-2)" "unprognostic (2.73e-2)" "unprognostic (1.47e-2)" "unprognostic (4.18e-3)" "potential prognostic favorable (1.00e-3)" "unprognostic (7.74e-3)" "unprognostic (1.36e-3)" "unprognostic (1.76e-1)" "unprognostic (3.16e-1)" "potential prognostic unfavorable (1.02e-4)" "unprognostic (3.54e-1)" "unprognostic (1.49e-3)" "unprognostic (1.45e-1)" "unprognostic (2.48e-2)" "unprognostic (3.01e-2)" "unprognostic (8.39e-2)" "unprognostic (9.67e-2)" "unprognostic (1.37e-1)" "unprognostic (1.85e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-2)" "unprognostic (6.59e-3)" "unprognostic (4.64e-2)" "unprognostic (4.00e-2)" "unprognostic (2.21e-1)" "unprognostic (2.80e-2)" "unprognostic (1.29e-3)" OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1220.0;pancreas: 666.4" "Cell type enhanced" "Detected in many" "Enteric stem cells: 3771.2;Enteric transient amplifying cells: 1899.8;Gastric progenitor cells: 1996.8;Neutrophil progenitors: 3094.3;Pancreatic acinar cells: 888.4;Paneth cells: 6605.5;Prostatic club cells: 5605.8;Prostatic hillock cells: 1459.4" "Cell type enhanced" "Detected in many" "Glandular cells: 5605.8;Neutrophils: 3094.3;Proliferating cells: 1996.8;Secretory gland support: 6605.5;Stem cells: 3771.2" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 12 "Colon Adenocarcinoma (TCGA): 1060.5;Pancreatic Adenocarcinoma (TCGA): 847.1;Rectum Adenocarcinoma (TCGA): 758.1;Stomach Adenocarcinoma (TCGA): 974.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "colorectal cancer: 123.7;Gastric cancer: 42.1" "Colon - Colon enterocytes, Lung - Neutrophils_1, Prostate - Urothelial cells, Spleen - Neutrophils_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" "Neutrophils: 315806144.3" "Tissue enriched" "Detected in many" "intestine: 120935517.4" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" "Cell adhesion" Yes NA 840000 "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 27 "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: " "unprognostic (2.03e-1)" "unprognostic (8.08e-3)" "unprognostic (3.62e-3)" "unprognostic (8.93e-2)" "unprognostic (8.87e-2)" "unprognostic (8.59e-3)" "unprognostic (5.80e-2)" "unprognostic (1.47e-1)" "unprognostic (1.67e-3)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (8.54e-2)" "unprognostic (3.22e-1)" "unprognostic (6.21e-3)" "unprognostic (1.55e-1)" "unprognostic (6.87e-2)" "unprognostic (5.05e-2)" "unprognostic (1.80e-3)" "unprognostic (6.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.64e-3)" "unprognostic (4.90e-2)" "unprognostic (2.33e-1)" "unprognostic (5.08e-2)" OLFML2B DKFZP586L151 ENSG00000162745 "Olfactomedin like 2B" Q68BL8 1 161983192-162023869 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 52.2;Early spermatids: 67.3;Endometrial stromal cells: 28.7;Fibro-adipogenic progenitors: 39.7;Fibroblasts: 31.6;Hofbauer cells: 75.8;Kupffer cells: 49.2;Late primary spermatocytes: 143.4;Leydig cells: 29.5;Macrophages: 49.8;Myosatellite cells: 175.4;Pericytes: 47.8;Peritubular myoid cells: 41.8;Vascular smooth muscle cells: 32.2" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 75.8;Spermatogenic cell types: 143.4;Stem cells: 175.4" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 30.4;committed oligodendrocyte precursor: 13.2;deep-layer corticothalamic and 6b: 26.7;deep-layer intratelencephalic: 10.1;fibroblast: 29.3;hippocampal CA4: 23.4;midbrain-derived inhibitory: 29.0;vascular associated smooth muscle cell: 24.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "intermediate monocyte: 6.7;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 11 "monocytes: 6.7" "Cancer enhanced" "Detected in many" "Rhabdoid: 80.6;Sarcoma: 41.3" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Macrophages, Thyroid gland - Fibroblasts" "Group enriched" "Detected in all" 4 "hippocampal formation: 41.0;white matter: 11.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054136, HPA062739" Approved Approved Cytosol "Secreted - unknown location" "No annotated function" NA NA 42000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 1 Cytosol "HPA054136: , HPA062739: " "unprognostic (1.41e-1)" "unprognostic (2.21e-2)" "unprognostic (4.84e-2)" "unprognostic (3.10e-2)" "unprognostic (1.91e-2)" "unprognostic (6.84e-2)" "unprognostic (2.91e-2)" "unprognostic (1.06e-1)" "unprognostic (8.66e-3)" "unprognostic (2.96e-2)" "unprognostic (2.30e-2)" "unprognostic (3.59e-1)" "potential prognostic unfavorable (4.41e-6)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (3.16e-3)" "unprognostic (9.13e-2)" "unprognostic (2.84e-2)" "unprognostic (6.69e-2)" "unprognostic (9.74e-2)" "unprognostic (1.24e-3)" "unprognostic (7.44e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-1)" "unprognostic (3.42e-1)" "unprognostic (2.92e-1)" "unprognostic (3.55e-2)" "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (2.30e-2)" "unprognostic (8.61e-3)" "unprognostic (3.47e-2)" OLFML3 "HNOEL-iso, OLF44" ENSG00000116774 "Olfactomedin like 3" Q9NRN5 1 113979391-114035572 "Predicted intracellular proteins, Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 238.5" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 466.7;Endometrial stromal cells: 102.2;Fibroblasts: 261.8;Hepatic stellate cells: 664.8;Microglia: 67.5;Ovarian stromal cells: 171.2;Smooth muscle cells: 69.5" "Group enriched" "Detected in many" 6 "Fibroblasts: 261.8;Stellate cells: 664.8;Stromal cells: 466.7" "Group enriched" "Detected in some" 7 "central nervous system macrophage: 65.0;fibroblast: 125.7;pericyte: 32.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "myeloid DC: 2.1" "Lineage enriched" "Detected in single" 12 "dendritic cells: 2.1" "Cancer enhanced" "Detected in many" "Bone cancer: 137.5;testis cancer: 132.0" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Oocytes: 131758287.9" "Tissue enhanced" "Detected in all" "ovary: 313271977.6" HPA027991 Supported Vesicles "Secreted to extracellular matrix" "Developmental protein" NA NA 3100000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Vesicles "HPA027991: " "unprognostic (6.27e-3)" "unprognostic (8.04e-2)" "unprognostic (2.35e-1)" "unprognostic (5.04e-2)" "unprognostic (5.78e-2)" "unprognostic (2.41e-1)" "unprognostic (3.16e-1)" "unprognostic (4.21e-2)" "unprognostic (1.07e-1)" "unprognostic (2.09e-1)" "unprognostic (3.18e-2)" "unprognostic (9.12e-2)" "unprognostic (1.13e-1)" "unprognostic (2.97e-1)" "unprognostic (3.93e-2)" "unprognostic (8.59e-2)" "unprognostic (9.06e-3)" "unprognostic (5.84e-2)" "unprognostic (4.41e-2)" "unprognostic (8.68e-3)" "unprognostic (9.95e-3)" "unprognostic (9.03e-2)" "unprognostic (2.20e-2)" "unprognostic (2.29e-1)" "unprognostic (2.07e-1)" "unprognostic (4.94e-2)" "unprognostic (1.02e-1)" "unprognostic (5.55e-3)" "unprognostic (1.48e-1)" "unprognostic (9.37e-2)" "unprognostic (3.97e-1)" ONECUT1 "HNF-6, HNF6, HNF6A" ENSG00000169856 "One cut homeobox 1" Q9UBC0 15 52755053-52791078 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "gallbladder: 5.4;liver: 12.2;pancreas: 14.0;retina: 3.8" "Cell type enhanced" "Detected in some" "Cholangiocytes: 278.1;Hepatocytes: 116.3;Pancreatic acinar cells: 119.3;Pancreatic duct cells: 173.7;Retinal ganglion cells: 100.4;Retinal horizontal cells: 1041.8" "Group enriched" "Detected in some" 5 "Ductal cells: 278.1;Neuronal cells: 1041.8" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 16.5;oligodendrocyte precursor cell: 34.7" "Group enriched" "Detected in some" 6 "Liver Hepatocellular Carcinoma (TCGA): 5.5;Pancreatic Adenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 4.9" "Region enhanced" "Detected in single" "hypothalamus: 1.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2608 "intestine: 260800.0" HPA003457 Enhanced Supported Nucleoplasm NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 18: Liver cancer - Metabolism" "Cluster 109: Neurons - Neuronal signaling" 3 Nucleoplasm "HPA003457: " "unprognostic (6.48e-2)" "unprognostic (1.82e-1)" "unprognostic (2.43e-2)" "unprognostic (9.80e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-2)" ONECUT3 ENSG00000205922 "One cut homeobox 3" O60422 19 1753506-1780988 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 2.0;stomach 1: 4.1" "Cell type enriched" "Detected in some" 11 "Retinal horizontal cells: 342.6" "Cell type enriched" "Detected in some" 11 "Neuronal cells: 342.6" "Cell type enhanced" "Detected in single" "splatter: 1.5" "Group enriched" "Detected in some" 7 "Pancreatic Adenocarcinoma (TCGA): 5.5;Stomach Adenocarcinoma (TCGA): 5.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gastric cancer: 15.3" "Low region specificity" "Detected in single" "Region enhanced" "Detected in single" "hypothalamus: 2.4" "Cell type enriched" "Detected in single" 18053 "Capillaries: 1805292.7" "Not detected" "Not detected" HPA059936 Supported Nucleoplasm NA NA "Cluster 42: Retina - Visual perception" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 109: Neurons - Neuronal signaling" 3 Nucleoplasm "HPA059936: " "unprognostic (1.50e-1)" "unprognostic (3.82e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" OPRL1 "KOR-3, NOCIR, NOPr, OOR, ORL1, PNOCR" ENSG00000125510 "Opioid related nociceptin receptor 1" P41146 20 64080082-64100643 "G-protein coupled receptors, Predicted membrane proteins" Behavior "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 12.1;lymphoid tissue: 3.8;testis: 6.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 6.9;Brain inhibitory neurons: 8.4;Ependymal cells: 1.8;Microglia: 6.1;Neutrophils: 2.6;Other brain neurons: 11.9" "Cell type enhanced" "Detected in some" "Glial cells: 6.1;Neuronal cells: 11.9;Neutrophils: 2.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 3.9;eosinophil: 5.8;intermediate monocyte: 5.5;myeloid DC: 4.7;neutrophil: 4.9;non-classical monocyte: 12.5" "Group enriched" "Detected in many" 11 "dendritic cells: 4.7;granulocytes: 5.8;monocytes: 12.5" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA064863 Approved "Primary cilium,Primary cilium tip" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 98: Neurons - Neurotransmission & signaling" 5 "Primary cilium, Primary cilium tip" "HPA064863: " "unprognostic (2.42e-1)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (6.59e-2)" "unprognostic (3.65e-1)" "unprognostic (2.78e-1)" "unprognostic (1.09e-1)" "unprognostic (9.54e-2)" "unprognostic (4.49e-2)" "unprognostic (5.52e-2)" OR6P1 ENSG00000186440 "Olfactory receptor family 6 subfamily P member 1" Q8NGX9 1 158560606-158570580 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Late spermatids: 1.0" "Cell type enriched" "Detected in single" 5 "Spermatogenic cell types: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047466 Uncertain Approved "Mid piece,Principal piece" NA NA "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Mid piece, Principal piece" "HPA047466: " ORC6 ORC6L ENSG00000091651 "Origin recognition complex subunit 6" Q9Y5N6 16 46689643-46698394 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA replication" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 9.7;lymphoid tissue: 6.9;testis: 9.3" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 45.5;Differentiating spermatogonia: 91.2;Early primary spermatocytes: 154.4;Erythrocyte progenitors: 86.7;Esophageal basal cells: 36.6;Extravillous trophoblasts: 40.9;Megakaryocyte progenitors: 67.6;Migrating cytotrophoblasts: 53.2;Monocyte progenitors: 39.3;Sertoli cells: 39.9" "Cell type enhanced" "Detected in many" "Erythrocytes: 86.7;Megakaryocytes: 67.6;Spermatogenic cell types: 154.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1520 "Granulosa cells: 152016.1" "Not detected" "Not detected" "CAB016330, HPA072587" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 14: Neurons - Synaptic function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 16 "Nucleoplasm, Nucleoli fibrillar center" "CAB016330: , HPA072587: " "unprognostic (1.02e-3)" "unprognostic (1.26e-2)" "unprognostic (9.28e-3)" "unprognostic (1.89e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-2)" "unprognostic (4.00e-3)" "unprognostic (4.58e-3)" "unprognostic (3.69e-1)" "validated prognostic unfavorable (4.56e-6)" "validated prognostic unfavorable (5.40e-6)" "potential prognostic unfavorable (1.54e-7)" "validated prognostic unfavorable (2.22e-8)" "validated prognostic unfavorable (7.03e-6)" "potential prognostic unfavorable (3.39e-5)" "unprognostic (2.02e-3)" "unprognostic (2.01e-1)" "unprognostic (1.84e-2)" "unprognostic (4.57e-2)" "unprognostic (1.76e-1)" "validated prognostic unfavorable (7.66e-4)" "validated prognostic unfavorable (8.00e-5)" "unprognostic (2.70e-2)" "unprognostic (2.40e-1)" "unprognostic (5.08e-2)" "unprognostic (9.08e-3)" "unprognostic (3.91e-1)" "unprognostic (3.97e-1)" "unprognostic (3.75e-3)" "unprognostic (6.67e-2)" OSTM1 "GL, HSPC019" ENSG00000081087 "Osteoclastogenesis associated transmembrane protein 1" Q86WC4 6 108029245-108165854 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Osteopetrosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Melanocytes: 443.4;Neutrophils: 191.5;Retinal pigment epithelial cells: 247.3" "Cell type enhanced" "Detected in all" "Pigment cells: 443.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 323396.9;Macrophages: 335128.1" "Tissue enriched" "Detected in many" "heart muscle: 8484525.1" HPA010851 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No 77000 "Cluster 28: Neutrophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 6 Cytosol "Nucleoplasm, Vesicles" "HPA010851: " "unprognostic (2.99e-1)" "unprognostic (3.97e-3)" "potential prognostic unfavorable (4.14e-5)" "unprognostic (6.06e-3)" "unprognostic (2.06e-1)" "unprognostic (1.92e-1)" "unprognostic (4.14e-1)" "unprognostic (5.26e-3)" "unprognostic (5.01e-3)" "unprognostic (9.84e-3)" "potential prognostic favorable (2.20e-6)" "unprognostic (3.90e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" "unprognostic (2.56e-2)" "unprognostic (3.23e-1)" "unprognostic (1.33e-1)" "unprognostic (9.39e-3)" "unprognostic (7.84e-2)" "unprognostic (6.16e-2)" "potential prognostic unfavorable (4.46e-5)" "unprognostic (4.78e-2)" "unprognostic (2.39e-1)" "unprognostic (1.38e-1)" "unprognostic (3.04e-2)" "unprognostic (5.89e-3)" "unprognostic (9.64e-2)" "unprognostic (3.97e-3)" "unprognostic (3.05e-1)" "unprognostic (2.95e-1)" "unprognostic (8.85e-2)" OTC "OTC1, OTCase, OTCD" ENSG00000036473 "Ornithine transcarbamylase" P00480 X 38352586-38421446 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Arginine biosynthesis, Urea cycle" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 122 "intestine: 105.7;liver: 353.1" "Cell type enhanced" "Detected in some" "Enteric stem cells: 23.7;Enteric transient amplifying cells: 37.6;Enterocytes: 82.9;Hepatocytes: 136.0;Lymphatic endothelial cells: 28.5;Paneth cells: 46.4" "Cell type enhanced" "Detected in some" "Enterocytes: 82.9;Hepatocytes: 136.0;Proliferating cells: 37.6;Secretory gland support: 46.4" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in some" 18 "Liver Hepatocellular Carcinoma (TCGA): 75.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.0" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Hepatocytes: 764731102.6" "Group enriched" "Detected in some" "liver: 177699778.9;pancreas: 67847019.7;skin: 52173714.1" "HPA000243, HPA000570" Enhanced Supported Mitochondria NA NA 4400000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 2 Mitochondria "HPA000243: , HPA000570: " "unprognostic (1.48e-1)" "unprognostic (1.72e-1)" "unprognostic (6.77e-3)" "unprognostic (3.12e-2)" "unprognostic (3.44e-2)" "unprognostic (1.34e-2)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (8.34e-4)" "unprognostic (1.65e-2)" OTOP2 ENSG00000183034 "Otopetrin 2" Q7RTS6 17 74922950-74933912 "Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "intestine: 18.8;testis: 4.7" "Group enriched" "Detected in some" 4 "Colonocytes: 122.6;Late spermatids: 35.9" "Group enriched" "Detected in some" 18 "Enterocytes: 122.6;Spermatogenic cell types: 35.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Gallbladder cancer: 2.0" "Colon - Colon enterocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Late spermatids" "Region enriched" "Detected in some" 12 "olfactory bulb: 12.7" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 294 "bone marrow: 29358.9" "HPA024524, HPA053090" Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Intestine - Digestion" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Plasma membrane" "HPA024524: , HPA053090: " OTP ENSG00000171540 "Orthopedia homeobox" Q5XKR4 5 77628712-77638713 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 70 "brain: 17.3" "Group enriched" "Detected in some" 12 "Early primary spermatocytes: 6.4;Other brain neurons: 19.6" "Group enriched" "Detected in some" 12 "Neuronal cells: 19.6;Spermatogenic cell types: 6.4" "Group enriched" "Detected in some" 9 "amygdala excitatory: 5.0;splatter: 3.9" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 3.0" "Region enhanced" "Detected in many" "hypothalamus: 61.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 21 "lymphoma: 12.7;Rhabdoid: 6.1" "Region enriched" "Detected in many" 7 "hypothalamus: 20.0" "Group enriched" "Detected in some" 4 "basal ganglia: 8.4;hypothalamus: 22.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA059342 Enhanced Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 59: Leukemia - T-cell receptor" "Cluster 109: Neurons - Neuronal signaling" 5 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "HPA059342: " "unprognostic (2.63e-2)" "potential prognostic unfavorable (1.55e-5)" OTUD7B "CEZANNE, ZA20D1" ENSG00000264522 "OTU deubiquitinase 7B" Q6GQQ9 1 149937812-150010726 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 252.0;Oligodendrocytes: 251.3;Schwann cells: 246.2" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "oligodendrocyte: 354.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 1726125.0" "Tissue enhanced" "Detected in many" "skeletal muscle: 11134866.5" "HPA027045, HPA076357" Supported Uncertain "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 29 Microtubules "Cytokinetic bridge, Mitotic spindle" "HPA027045: , HPA076357: " "unprognostic (8.26e-2)" "unprognostic (2.12e-1)" "unprognostic (2.63e-1)" "unprognostic (2.53e-2)" "unprognostic (1.24e-1)" "unprognostic (1.20e-1)" "unprognostic (8.77e-2)" "unprognostic (1.90e-1)" "unprognostic (2.43e-2)" "validated prognostic favorable (4.33e-7)" "validated prognostic favorable (1.96e-4)" "unprognostic (8.64e-2)" "unprognostic (3.15e-3)" "unprognostic (8.06e-2)" "unprognostic (1.24e-1)" "unprognostic (4.09e-2)" "unprognostic (5.35e-2)" "unprognostic (3.49e-2)" "unprognostic (4.60e-3)" "unprognostic (3.81e-3)" "unprognostic (1.30e-1)" "unprognostic (2.29e-2)" "unprognostic (2.78e-1)" "unprognostic (1.23e-1)" "unprognostic (2.37e-1)" "unprognostic (1.54e-1)" "unprognostic (2.86e-2)" "unprognostic (8.81e-2)" OTX2 ENSG00000165588 "Orthodenticle homeobox 2" P32243 14 56799905-56816693 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "choroid plexus: 151.9;retina: 259.6" "Group enriched" "Detected in some" 8 "Choroid plexus epithelial cells: 232.4;Cone photoreceptor cells: 269.1;Retinal bipolar cells: 316.8;Retinal pigment epithelial cells: 264.3;Rod photoreceptor cells: 357.2" "Group enriched" "Detected in some" 16 "Ciliated cells: 232.4;Neuronal cells: 357.2;Pigment cells: 264.3" "Group enriched" "Detected in many" 20 "choroid plexus epithelial cell: 337.2;midbrain-derived inhibitory: 238.9" "Cancer enriched" "Detected in some" 23 "Testicular Germ Cell Tumor (TCGA): 32.5" "Region enriched" "Detected in many" 8 "choroid plexus: 230.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 44.8;Brain cancer: 32.5;Uterine cancer: 29.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000633, HPA001123" Uncertain Supported Nucleoplasm,Vesicles NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 4 Nucleoplasm Vesicles "HPA000633: , HPA001123: " "unprognostic (4.97e-1)" "unprognostic (1.12e-1)" "unprognostic (1.26e-2)" "unprognostic (9.90e-3)" "unprognostic (9.07e-2)" "unprognostic (3.55e-2)" OVOL1 HOVO1 ENSG00000172818 "Ovo like transcriptional repressor 1" O14753 11 65787063-65797214 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 55.4;skin 1: 49.1;testis: 33.8" "Cell type enhanced" "Detected in many" "Breast secretory cells: 143.1;Endometrial luminal cells: 162.7;Epididymal basal cells: 145.3;Esophageal apical cells: 604.2;Esophageal suprabasal cells: 233.0;Late primary spermatocytes: 191.9;Late spermatids: 137.8;Ocular epithelial cells: 158.3;Syncytiotrophoblasts: 392.4;Urothelial cells: 243.2" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 604.2;Barrier epithelial cells: 243.2;Suprabasal cells: 233.0;Trophoblast cells: 392.4" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA003984 Uncertain Approved Nucleoplasm Yes NA "Cluster 39: Testis - Nuclear processes" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 5 Nucleoplasm "HPA003984: " "unprognostic (9.27e-3)" "unprognostic (1.38e-2)" "unprognostic (4.36e-2)" "unprognostic (2.39e-1)" "unprognostic (2.05e-1)" "unprognostic (1.64e-3)" "unprognostic (1.77e-1)" "unprognostic (2.70e-1)" "validated prognostic favorable (1.95e-7)" "validated prognostic favorable (1.53e-4)" "potential prognostic favorable (1.84e-5)" "unprognostic (1.96e-1)" "unprognostic (1.45e-3)" "unprognostic (5.03e-3)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (2.27e-2)" "unprognostic (3.54e-3)" "unprognostic (1.65e-2)" "unprognostic (3.31e-1)" "unprognostic (7.20e-2)" "unprognostic (2.19e-1)" "unprognostic (4.94e-2)" "unprognostic (5.27e-2)" "unprognostic (1.37e-1)" "unprognostic (1.41e-1)" "unprognostic (1.46e-1)" OXCT1 "OXCT, SCOT" ENSG00000083720 "3-oxoacid CoA-transferase 1" P55809 5 41730065-41870425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 230.2" "Cell type enhanced" "Detected in many" "Epididymal clear cells: 534.8;Parietal cells: 265.2" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 534.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Kidney Chromophobe (TCGA): 190.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Skin - Mitotic cells (Skin), Stomach - Parietal cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 313971341.6" "Group enriched" "Detected in all" "cerebral cortex: 176914017.7;heart muscle: 230845361.9" "HPA012047, HPA061425" Enhanced Enhanced Mitochondria NA NA 660000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 29: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 10 Mitochondria "HPA012047: , HPA061425: " "unprognostic (1.48e-1)" "unprognostic (5.54e-2)" "unprognostic (7.97e-2)" "unprognostic (1.18e-2)" "unprognostic (1.31e-1)" "unprognostic (5.66e-3)" "unprognostic (1.91e-1)" "unprognostic (3.80e-2)" "unprognostic (7.03e-2)" "unprognostic (2.94e-1)" "potential prognostic favorable (5.36e-6)" "unprognostic (9.09e-3)" "unprognostic (2.71e-2)" "potential prognostic unfavorable (3.00e-4)" "unprognostic (8.96e-2)" "unprognostic (1.13e-1)" "unprognostic (2.59e-2)" "unprognostic (5.34e-2)" "unprognostic (2.84e-2)" "unprognostic (1.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.39e-3)" "unprognostic (3.67e-1)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (3.18e-5)" "unprognostic (9.33e-2)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (3.23e-4)" "unprognostic (9.36e-2)" OXSM "CEM1, FASN2D, FLJ20604, KS" ENSG00000151093 "3-oxoacyl-ACP synthase, mitochondrial" Q9NWU1 3 25782917-25794534 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 268.3;Early spermatids: 167.8;Epicardial cells: 75.0;Late primary spermatocytes: 139.6;Late spermatids: 147.9" "Group enriched" "Detected in all" 4 "Barrier epithelial cells: 75.0;Myocytes: 268.3;Spermatogenic cell types: 167.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 18011205.7;Large ducts: 23494342.9" "Low tissue specificity" "Detected in many" "HPA021293, HPA021300, HPA021337" Enhanced Approved Mitochondria,Cytosol No No 10000 "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 5 "Mitochondria, Cytosol" "HPA021293: , HPA021300: , HPA021337: " "unprognostic (1.37e-1)" "unprognostic (5.58e-3)" "unprognostic (6.13e-2)" "unprognostic (1.34e-1)" "unprognostic (1.55e-2)" "unprognostic (1.10e-2)" "unprognostic (3.76e-1)" "potential prognostic favorable (3.89e-4)" "unprognostic (5.54e-2)" "unprognostic (3.02e-3)" "potential prognostic favorable (6.68e-11)" "unprognostic (9.74e-3)" "unprognostic (6.91e-3)" "unprognostic (7.34e-3)" "unprognostic (1.39e-1)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (2.10e-1)" "unprognostic (4.53e-2)" "unprognostic (1.01e-1)" "unprognostic (4.41e-2)" "unprognostic (2.76e-1)" "unprognostic (2.55e-1)" "unprognostic (7.22e-2)" "potential prognostic favorable (9.26e-4)" "unprognostic (6.88e-2)" "unprognostic (3.52e-2)" "unprognostic (4.80e-2)" "unprognostic (2.51e-1)" "unprognostic (4.49e-2)" "unprognostic (2.58e-1)" P3H2 "FLJ10718, LEPREL1, MLAT4" ENSG00000090530 "Prolyl 3-hydroxylase 2" Q8IVL5 3 189956728-190122437 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 848.3;Alveolar cells type 2: 439.1;Basal keratinocytes: 349.4;Foveolar cells: 401.2;Loop of henle epithelial cells: 583.4;Ocular epithelial cells: 375.8;Pituicytes/FSCs: 522.8;Podocytes: 688.9;Prostatic glandular cells: 368.5;Proximal tubule cells: 1160.5;Renal collecting duct intercalated cells: 355.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 848.3;Renal nephron cells: 1160.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 389.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 22 "plasmacytoid DC: 28.9" "Lineage enriched" "Detected in single" 112 "dendritic cells: 28.9" "Cancer enhanced" "Detected in all" "Kidney cancer: 132.1" "Breast - Breast myoepithelial cells, Lung - Alveolar cells type 2, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 3382996.5" "Not detected" "Not detected" "HPA007890, HPA013355, HPA013611" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" "Intracellular and membrane" Enzyme NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 22: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Golgi apparatus" "Nucleoplasm, Vesicles, Cytosol" "HPA007890: , HPA013355: , HPA013611: " "unprognostic (3.16e-1)" "unprognostic (1.35e-2)" "unprognostic (1.21e-1)" "unprognostic (4.55e-1)" "unprognostic (1.06e-2)" "unprognostic (7.85e-3)" "unprognostic (3.08e-3)" "unprognostic (1.06e-1)" "unprognostic (3.70e-3)" "unprognostic (9.14e-3)" "unprognostic (1.81e-1)" "unprognostic (2.46e-1)" "unprognostic (5.35e-2)" "unprognostic (1.06e-1)" "unprognostic (8.81e-2)" "unprognostic (1.39e-1)" "unprognostic (1.53e-1)" "unprognostic (9.64e-2)" "unprognostic (2.73e-1)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (1.20e-1)" "unprognostic (2.68e-1)" "unprognostic (1.15e-1)" "unprognostic (1.36e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-3)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.24e-1)" P4HA1 "C-P4Halpha(I), P4HA" ENSG00000122884 "Prolyl 4-hydroxylase subunit alpha 1" P13674 10 73007217-73096974 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 565.9;Thymic myoid cells: 439.2" "Cell type enhanced" "Detected in all" "Myocytes: 565.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 23268264.9" "Low tissue specificity" "Detected in all" "HPA007599, HPA026593" Enhanced Supported "Endoplasmic reticulum,Vesicles,Mitochondria" "Intracellular and membrane" Enzyme Yes No 85000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 55: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 75: Non-specific - Chaperones and protein folding" 51 "Endoplasmic reticulum" "Vesicles, Mitochondria" "HPA007599: , HPA026593: " "unprognostic (1.20e-1)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (3.02e-2)" "unprognostic (7.95e-2)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (3.90e-1)" "potential prognostic unfavorable (4.15e-4)" "potential prognostic unfavorable (1.45e-7)" "unprognostic (3.74e-3)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (4.02e-6)" "unprognostic (3.96e-1)" "unprognostic (1.24e-1)" "unprognostic (2.79e-3)" "unprognostic (1.75e-2)" "unprognostic (5.90e-2)" "unprognostic (5.61e-2)" "unprognostic (3.23e-2)" "unprognostic (5.57e-3)" "potential prognostic unfavorable (7.01e-4)" "unprognostic (1.01e-3)" "unprognostic (3.10e-2)" "unprognostic (3.38e-1)" "unprognostic (1.70e-1)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "unprognostic (1.77e-1)" "unprognostic (4.35e-3)" "unprognostic (2.94e-2)" P4HA2 "C-P4Halpha(II), lncRNA-PE" ENSG00000072682 "Prolyl 4-hydroxylase subunit alpha 2" O15460 5 132190147-132295315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 190.2;Decidual stromal cells: 137.0;Epicardial cells: 211.5;Proximal tubule cells: 198.1" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 211.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Pancreatic islets: 4635752.7" "Group enriched" "Detected in many" "liver: 2293096.0;skin: 8781674.1" "HPA016997, HPA027824, CAB062557" Enhanced Enhanced "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Enzyme No No 15000 "Cluster 35: Neutrophils - Protein binding" "Cluster 60: Stomach - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 108: Fibroblasts - ECM organization" 18 "Endoplasmic reticulum, Vesicles" "CAB062557: , HPA016997: , HPA027824: " "unprognostic (2.74e-1)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (5.30e-2)" "unprognostic (4.80e-2)" "unprognostic (2.14e-3)" "unprognostic (3.33e-2)" "unprognostic (3.40e-3)" "potential prognostic unfavorable (2.05e-4)" "potential prognostic favorable (4.56e-4)" "unprognostic (3.19e-1)" "potential prognostic unfavorable (5.23e-5)" "potential prognostic unfavorable (9.38e-4)" "unprognostic (1.87e-1)" "unprognostic (9.81e-3)" "potential prognostic unfavorable (7.16e-5)" "unprognostic (1.03e-2)" "unprognostic (3.14e-2)" "unprognostic (1.24e-1)" "unprognostic (2.03e-3)" "unprognostic (5.57e-2)" "unprognostic (2.03e-2)" "unprognostic (2.42e-1)" "unprognostic (2.25e-1)" "unprognostic (9.08e-2)" "unprognostic (5.29e-2)" "unprognostic (9.59e-3)" "unprognostic (2.64e-1)" "unprognostic (1.69e-1)" "unprognostic (5.67e-2)" P4HB "DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PO4DB, PO4HB, PROHB" ENSG00000185624 "Prolyl 4-hydroxylase subunit beta" P07237 17 81843159-81860856 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Isomerase" "Craniosynostosis, Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 2108.3" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2747.6;Esophageal suprabasal cells: 1072.3;Extravillous trophoblasts: 1918.6;Migrating cytotrophoblasts: 1116.0;Pancreatic acinar cells: 2020.9;Syncytiotrophoblasts: 1193.1" "Cell type enhanced" "Detected in all" "Acinar cells: 2020.9;Apical squamous epithelial cells: 2747.6;Trophoblast cells: 1918.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 4093646367.7;Pancreatic islets: 4462404683.7" "Tissue enhanced" "Detected in all" "pancreas: 7865550654.3" "CAB012463, HPA018884" Enhanced Supported "Endoplasmic reticulum" "Intracellular and membrane" Enzyme No No 72000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 103 "Endoplasmic reticulum" "CAB012463: , HPA018884: " "unprognostic (8.56e-2)" "unprognostic (2.58e-1)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (3.87e-4)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (9.41e-3)" "unprognostic (3.41e-3)" "unprognostic (6.88e-2)" "unprognostic (4.46e-2)" "potential prognostic favorable (5.44e-4)" "potential prognostic unfavorable (5.26e-6)" "unprognostic (6.34e-3)" "unprognostic (2.26e-1)" "unprognostic (1.91e-3)" "unprognostic (4.06e-2)" "unprognostic (1.85e-3)" "unprognostic (3.73e-2)" "unprognostic (1.31e-1)" "unprognostic (6.36e-2)" "unprognostic (1.08e-2)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (2.74e-1)" "unprognostic (2.27e-1)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (6.12e-2)" "unprognostic (1.94e-1)" "unprognostic (1.58e-3)" "unprognostic (5.43e-2)" PABIR1 "C9orf42, FAM122A, MGC17347" ENSG00000187866 "PP2A Aalpha (PPP2R1A) and B55A (PPP2R2A) interacting phosphatase regulator 1" Q96E09 9 68780065-68785566 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 240186.8" "Tissue enhanced" "Detected in many" "bone marrow: 3249045.1" HPA056646 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 5: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 21 "Nucleoplasm, Nuclear bodies" "HPA056646: " "unprognostic (1.18e-2)" "unprognostic (5.49e-2)" "unprognostic (3.24e-1)" "unprognostic (5.81e-3)" "unprognostic (2.65e-1)" "unprognostic (1.52e-1)" "unprognostic (2.78e-1)" "unprognostic (3.06e-1)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "validated prognostic favorable (5.00e-8)" "validated prognostic favorable (6.12e-5)" "unprognostic (6.04e-2)" "unprognostic (5.02e-1)" "unprognostic (1.63e-1)" "unprognostic (2.17e-2)" "unprognostic (4.15e-1)" "unprognostic (7.47e-2)" "unprognostic (3.22e-2)" "unprognostic (1.77e-2)" "unprognostic (1.37e-1)" "unprognostic (3.48e-2)" "unprognostic (4.89e-2)" "unprognostic (8.13e-2)" "unprognostic (3.56e-1)" "unprognostic (2.60e-1)" "unprognostic (2.19e-2)" "unprognostic (4.23e-3)" "unprognostic (5.17e-2)" "unprognostic (3.12e-1)" "unprognostic (9.18e-3)" PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 577.8;Neutrophils: 1361.0;Pancreatic acinar cells: 524.8" "Cell type enhanced" "Detected in all" "Neutrophils: 1361.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 96.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Approved "Nuclear speckles,Vesicles,Plasma membrane,Primary cilium,Centriolar satellite" NA NA 1400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 49: Hindbrain - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 24: Neutrophils - Innate immunity signal integration" 48 "Nuclear speckles, Plasma membrane" "Vesicles, Primary cilium, Centriolar satellite" "HPA049854: , HPA056520: " "unprognostic (2.67e-3)" "unprognostic (4.28e-2)" "unprognostic (9.66e-2)" "unprognostic (2.74e-2)" "unprognostic (2.92e-2)" "unprognostic (1.66e-3)" "unprognostic (1.11e-2)" "unprognostic (3.95e-2)" "unprognostic (1.82e-1)" "unprognostic (4.21e-1)" "validated prognostic favorable (3.95e-7)" "validated prognostic favorable (2.02e-5)" "unprognostic (1.99e-3)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (2.34e-2)" "unprognostic (3.03e-1)" "unprognostic (1.25e-1)" "unprognostic (8.54e-2)" "unprognostic (2.17e-2)" "unprognostic (5.80e-2)" "unprognostic (1.92e-1)" "unprognostic (2.20e-2)" "unprognostic (2.56e-1)" "unprognostic (1.50e-1)" "unprognostic (3.27e-2)" "unprognostic (3.43e-2)" "unprognostic (2.24e-1)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" "unprognostic (7.72e-3)" "unprognostic (3.78e-2)" PAF1 "F23149_1, FLJ11123, PD2" ENSG00000006712 "PAF1 homolog, Paf1/RNA polymerase II complex component" Q8N7H5 19 39385629-39391154 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 157.3;Late primary spermatocytes: 137.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 157.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 8869265.6;Neutrophils: 7701446.3" "Low tissue specificity" "Detected in many" "HPA041875, HPA071954" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 79 Nucleoplasm "Nucleoli fibrillar center, Vesicles" "HPA041875: , HPA071954: " "unprognostic (5.82e-3)" "unprognostic (7.57e-2)" "unprognostic (2.68e-1)" "unprognostic (4.91e-2)" "unprognostic (6.29e-2)" "unprognostic (7.80e-2)" "unprognostic (2.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-1)" "unprognostic (8.60e-2)" "potential prognostic favorable (3.74e-5)" "unprognostic (3.07e-3)" "unprognostic (3.02e-2)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (5.89e-2)" "unprognostic (6.32e-2)" "unprognostic (2.39e-1)" "unprognostic (4.34e-3)" "unprognostic (2.93e-1)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (2.45e-2)" "unprognostic (3.02e-2)" "unprognostic (9.17e-2)" "unprognostic (2.55e-1)" "unprognostic (5.01e-2)" "unprognostic (3.05e-2)" "unprognostic (9.30e-2)" "unprognostic (2.64e-1)" "unprognostic (1.35e-1)" "unprognostic (9.77e-2)" PAFAH1B3 ENSG00000079462 "Platelet activating factor acetylhydrolase 1b catalytic subunit 3" Q15102 19 42297033-42303546 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 258.1;Esophageal basal cells: 164.8;Oocytes: 225.6;Undifferentiated spermatogonia: 150.1" "Cell type enhanced" "Detected in many" "Oocytes: 225.6;Spermatogenic cell types: 258.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Outer root sheath cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 61870836.5" "Low tissue specificity" "Detected in all" HPA035639 Uncertain Approved "Intermediate filaments" NA NA 300000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 4: Non-specific - Transcription" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 17 "Intermediate filaments" "HPA035639: " "unprognostic (2.89e-2)" "unprognostic (2.11e-1)" "unprognostic (8.22e-2)" "unprognostic (7.14e-3)" "unprognostic (1.23e-1)" "unprognostic (8.27e-2)" "unprognostic (4.81e-2)" "unprognostic (3.22e-1)" "unprognostic (4.90e-2)" "unprognostic (2.98e-2)" "unprognostic (1.24e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-1)" "validated prognostic unfavorable (7.69e-5)" "validated prognostic unfavorable (5.77e-5)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.41e-2)" "potential prognostic favorable (8.41e-4)" "unprognostic (1.73e-1)" "unprognostic (7.56e-2)" "unprognostic (3.04e-1)" "unprognostic (2.52e-1)" "unprognostic (1.30e-1)" "unprognostic (2.00e-1)" "unprognostic (3.29e-1)" "unprognostic (9.57e-3)" "unprognostic (1.70e-1)" "unprognostic (2.54e-1)" "unprognostic (4.91e-2)" "unprognostic (1.02e-1)" "unprognostic (1.92e-1)" PAH PH ENSG00000171759 "Phenylalanine hydroxylase" P00439 12 102836889-102958410 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Phenylalanine catabolism" "Allosteric enzyme, Monooxygenase, Oxidoreductase" "Disease variant, FDA approved drug targets, Phenylketonuria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "kidney: 463.6;liver: 1316.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 264.0;Corticotrophs: 102.3;Early spermatids: 184.7;Hepatocytes: 1063.0;Late primary spermatocytes: 143.2;Proximal tubule cells: 434.8" "Cell type enhanced" "Detected in many" "Ductal cells: 264.0;Hepatocytes: 1063.0;Renal nephron cells: 434.8;Spermatogenic cell types: 184.7" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 35.4" "Cancer enriched" "Detected in many" 13 "Liver Hepatocellular Carcinoma (TCGA): 322.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "liver cancer: 43.8" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Glomeruli: 190507481.7;Hepatocytes: 234686106.2;Proximal tubules: 262260520.8" "Tissue enriched" "Detected in some" "liver: 129427127.4" "HPA028407, HPA031642" Enhanced Approved "Endoplasmic reticulum,Vesicles" No NA 9900 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Endoplasmic reticulum, Vesicles" "HPA028407: , HPA031642: " "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "unprognostic (5.18e-1)" "unprognostic (8.74e-2)" "unprognostic (1.21e-1)" "unprognostic (5.93e-2)" "potential prognostic favorable (4.17e-5)" "unprognostic (2.19e-3)" "unprognostic (2.89e-1)" "potential prognostic favorable (2.34e-4)" "unprognostic (1.50e-3)" "unprognostic (1.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (6.57e-4)" "unprognostic (9.79e-3)" "unprognostic (1.13e-1)" "unprognostic (1.74e-1)" "unprognostic (1.87e-2)" "unprognostic (3.35e-2)" "unprognostic (1.89e-1)" PAICS "ADE2H1, AIRC, PAIS" ENSG00000128050 "Phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase" P22234 4 56435741-56464578 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Purine biosynthesis" "Decarboxylase, Ligase, Lyase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 178.0;Erythrocyte progenitors: 217.2;Esophageal basal cells: 184.0;Extravillous trophoblasts: 183.5;Migrating cytotrophoblasts: 204.2" "Cell type enhanced" "Detected in all" "Erythrocytes: 217.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Hepatocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "liver: 60263354.7" "HPA035895, HPA041538" Approved Approved Cytosol Yes No 1200000 "Cluster 18: Non-specific - Translation" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 35 Cytosol "HPA035895: , HPA041538: " "unprognostic (6.37e-2)" "unprognostic (2.86e-3)" "unprognostic (2.60e-1)" "unprognostic (5.40e-3)" "unprognostic (3.11e-2)" "unprognostic (2.31e-1)" "unprognostic (6.71e-2)" "unprognostic (5.39e-3)" "unprognostic (2.69e-3)" "unprognostic (1.42e-3)" "unprognostic (2.18e-3)" "unprognostic (2.31e-1)" "unprognostic (1.17e-3)" "potential prognostic unfavorable (1.57e-5)" "unprognostic (4.04e-3)" "validated prognostic unfavorable (5.52e-5)" "validated prognostic unfavorable (2.41e-4)" "unprognostic (2.69e-1)" "unprognostic (2.08e-2)" "unprognostic (1.21e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.70e-5)" "unprognostic (9.14e-2)" "unprognostic (8.93e-2)" "potential prognostic favorable (2.73e-4)" "unprognostic (4.36e-2)" "unprognostic (8.30e-3)" "unprognostic (7.06e-2)" "unprognostic (1.68e-1)" "unprognostic (2.47e-3)" "unprognostic (7.96e-3)" PAIP1 ENSG00000172239 "Poly(A) binding protein interacting protein 1" Q9H074 5 43526267-43557758 "Predicted intracellular proteins" "Host-virus interaction, Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 534.2" "Cell type enhanced" "Detected in all" "Oocytes: 534.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA073653, HPA076187" Approved Enhanced "Plasma membrane,Cytosol" No No 95000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 41: Oocytes - Oogenesis" 26 "Plasma membrane, Cytosol" "HPA073653: , HPA076187: " "unprognostic (1.90e-1)" "unprognostic (1.25e-2)" "potential prognostic unfavorable (7.11e-4)" "unprognostic (3.37e-2)" "unprognostic (2.81e-1)" "unprognostic (2.95e-1)" "unprognostic (1.02e-1)" "unprognostic (5.30e-2)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (1.80e-6)" "unprognostic (1.23e-2)" "unprognostic (1.74e-1)" "unprognostic (2.99e-1)" "potential prognostic unfavorable (9.33e-7)" "unprognostic (2.33e-2)" "unprognostic (1.84e-2)" "unprognostic (1.06e-2)" "unprognostic (4.47e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-1)" "unprognostic (3.16e-2)" "potential prognostic unfavorable (6.01e-4)" "unprognostic (7.42e-3)" "unprognostic (6.37e-2)" "unprognostic (1.24e-2)" "unprognostic (3.61e-1)" "unprognostic (7.54e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-2)" "unprognostic (1.36e-1)" "unprognostic (9.72e-2)" PAK5 "KIAA1264, PAK7" ENSG00000101349 "P21 (RAC1) activated kinase 5" Q9P286 20 9537370-9839076 "Enzymes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 16.3;retina: 4.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 248.2;Brain inhibitory neurons: 236.2;Cone photoreceptor cells: 103.5;Corticotrophs: 265.5;Ependymal cells: 103.8;Gonadotrophs: 87.3;Oligodendrocyte progenitor cells: 93.7;Other brain neurons: 118.0;Retinal amacrine cells: 126.9;Retinal horizontal cells: 607.0" "Group enriched" "Detected in many" 4 "Neuronal cells: 607.0;Pituitary endocrine cells: 265.5" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 1.3;Kidney Chromophobe (TCGA): 2.0;Lung Squamous Cell Carcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 2.4" "Colon - Colon enteroendocrine cells, Kidney - Intercalated cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14206 "Astrocytes and Neuropil: 1579240.8;Microglia and Neuropil: 1862476.8;Neurons: 820080.2" "Tissue enriched" "Detected in single" 47004 "cerebral cortex: 4700401.4" "HPA020444, HPA071060" Approved Supported "Nucleoplasm,Nuclear membrane,Mitochondria,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 41 Nucleoplasm "Nuclear membrane, Mitochondria, Cytosol" "HPA020444: , HPA071060: " "unprognostic (1.31e-1)" "potential prognostic favorable (6.03e-5)" "unprognostic (7.02e-2)" "unprognostic (1.25e-2)" "unprognostic (3.24e-2)" PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2730.0;Medullary thymic epithelial cells: 940.9;Myonuclei: 2714.2;Salivary ionocytes: 885.2;Smooth muscle cells: 1507.4" "Cell type enhanced" "Detected in all" "Myocytes: 2730.0;Smooth muscle cells: 1507.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "testis cancer: 254.7" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Smooth muscle cells: 517922909.4" "Tissue enhanced" "Detected in all" "intestine: 299249962.1" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 12000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 14 "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: , HPA035905: " "unprognostic (2.18e-1)" "unprognostic (3.77e-2)" "unprognostic (2.47e-3)" "unprognostic (8.88e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-2)" "unprognostic (4.45e-1)" "unprognostic (2.99e-3)" "unprognostic (1.91e-1)" "unprognostic (1.18e-2)" "potential prognostic favorable (6.17e-5)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (9.22e-2)" "unprognostic (1.02e-1)" "unprognostic (1.97e-2)" "unprognostic (4.21e-3)" "unprognostic (2.66e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-2)" "unprognostic (8.86e-3)" "unprognostic (9.53e-2)" "unprognostic (2.40e-1)" "unprognostic (1.97e-1)" "unprognostic (4.67e-2)" "unprognostic (3.58e-1)" "unprognostic (1.79e-1)" "unprognostic (4.17e-2)" "unprognostic (1.61e-1)" "unprognostic (1.21e-2)" "unprognostic (3.60e-1)" PALM2AKAP2 PALM2-AKAP2 ENSG00000157654 "PALM2 and AKAP2 fusion" "Q8IXS6, Q9Y2D5" 9 109498325-110172512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 916.8;Alveolar cells type 1: 485.6;Ependymal cells: 455.4;Lymphatic endothelial cells: 404.0;Mast cells: 682.4;Oligodendrocytes: 987.2;Vascular endothelial cells: 648.1" "Cell type enhanced" "Detected in many" "Adipocytes: 916.8;Glial cells: 987.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.7;naive B-cell: 10.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pancreas - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 39729004.9" "Low tissue specificity" "Detected in all" "HPA058905, HPA074153, HPA076866" Uncertain Supported "Plasma membrane" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 5 "Plasma membrane" "HPA058905: , HPA074153: , HPA076866: " "unprognostic (1.47e-1)" "unprognostic (8.54e-2)" "potential prognostic unfavorable (1.88e-5)" "unprognostic (2.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.63e-1)" "unprognostic (6.42e-2)" "unprognostic (4.18e-2)" "validated prognostic favorable (3.03e-5)" "validated prognostic favorable (5.78e-5)" "potential prognostic unfavorable (7.73e-4)" "unprognostic (1.53e-1)" "unprognostic (3.83e-2)" "unprognostic (3.28e-2)" "unprognostic (7.13e-2)" "unprognostic (3.84e-3)" "unprognostic (2.77e-3)" "unprognostic (2.94e-2)" "unprognostic (4.11e-1)" "unprognostic (1.10e-1)" "unprognostic (1.43e-1)" "unprognostic (6.99e-3)" "unprognostic (8.08e-2)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (9.39e-2)" "unprognostic (3.44e-1)" PANK2 "C20orf48, FLJ11729, HARP, HSS, NBIA1, PKAN" ENSG00000125779 "Pantothenate kinase 2" Q9BZ23 20 3888839-3929887 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Coenzyme A biosynthesis" "Kinase, Transferase" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 428.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 428.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2902273.6" HPA008440 Approved Supported Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 24: Neutrophils - Innate immunity signal integration" 15 Cytosol "HPA008440: " "unprognostic (1.88e-1)" "unprognostic (8.86e-3)" "unprognostic (4.17e-3)" "unprognostic (5.67e-2)" "unprognostic (4.07e-1)" "unprognostic (2.52e-1)" "unprognostic (3.38e-1)" "unprognostic (2.13e-2)" "unprognostic (3.36e-1)" "unprognostic (1.19e-2)" "potential prognostic favorable (4.15e-5)" "unprognostic (3.25e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.71e-6)" "unprognostic (3.11e-3)" "unprognostic (1.23e-1)" "unprognostic (1.62e-1)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (9.70e-4)" "unprognostic (7.90e-2)" "unprognostic (3.52e-1)" "unprognostic (1.85e-1)" "unprognostic (1.18e-2)" "unprognostic (2.06e-1)" "unprognostic (3.22e-1)" "unprognostic (1.58e-2)" "unprognostic (1.36e-2)" "unprognostic (6.56e-2)" "unprognostic (6.54e-2)" "unprognostic (5.51e-2)" "unprognostic (1.45e-1)" PANK4 FLJ10782 ENSG00000157881 "Pantothenate kinase 4 (inactive)" Q9NVE7 1 2508537-2526597 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Coenzyme A biosynthesis" Hydrolase Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 7.1;Bergmann glia: 6.9;Brain excitatory neurons: 7.9;Brain inhibitory neurons: 8.7;Distal convoluted tubule cells: 5.4;Ependymal cells: 3.7;Loop of henle epithelial cells: 4.3;Microglia: 4.7;Oligodendrocyte progenitor cells: 6.7;Oligodendrocytes: 5.4;Other brain neurons: 5.9;Renal collecting duct intercalated cells: 5.6;Renal connecting tubule cells: 4.3;Retinal pigment epithelial cells: 4.3" "Cell type enhanced" "Detected in some" "Ductal cells: 5.6;Glial cells: 7.1;Neuronal cells: 8.7;Renal nephron cells: 5.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 3.7" "Immune cell enhanced" "Detected in single" "eosinophil: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA011723, HPA012036, HPA027961" Uncertain Approved Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 98: Neurons - Neurotransmission & signaling" 12 Cytosol "HPA011723: , HPA012036: , HPA027961: " "unprognostic (8.14e-2)" "unprognostic (1.24e-2)" "unprognostic (1.36e-1)" "unprognostic (2.64e-1)" "unprognostic (3.59e-1)" "unprognostic (5.00e-2)" "potential prognostic favorable (6.72e-4)" "unprognostic (9.18e-3)" "unprognostic (4.44e-2)" "unprognostic (3.90e-2)" "unprognostic (2.26e-2)" "unprognostic (7.72e-2)" "unprognostic (3.83e-2)" "unprognostic (6.49e-2)" "unprognostic (7.29e-2)" "unprognostic (2.57e-1)" "unprognostic (8.23e-2)" "unprognostic (1.49e-3)" "unprognostic (5.62e-3)" "unprognostic (8.56e-2)" "unprognostic (3.10e-2)" "unprognostic (5.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.39e-1)" "unprognostic (5.54e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.17e-1)" PAPOLA PAP ENSG00000090060 "Poly(A) polymerase alpha" P51003 14 96501433-96567116 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 1282.5" "Cell type enhanced" "Detected in all" "Trophoblast cells: 1282.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 9869664.2" "Tissue enhanced" "Detected in many" "intestine: 3461095.9" HPA001788 Supported Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 4 Nucleoplasm "HPA001788: " "unprognostic (5.94e-2)" "unprognostic (7.23e-2)" "unprognostic (3.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.93e-1)" "unprognostic (2.94e-1)" "unprognostic (1.69e-1)" "unprognostic (2.33e-1)" "unprognostic (2.66e-2)" "unprognostic (4.59e-2)" "potential prognostic favorable (8.61e-4)" "unprognostic (1.41e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (9.97e-4)" "unprognostic (1.54e-2)" "unprognostic (2.06e-1)" "unprognostic (3.21e-1)" "unprognostic (9.49e-2)" "unprognostic (1.44e-1)" "unprognostic (5.04e-1)" "potential prognostic unfavorable (7.64e-5)" "unprognostic (6.93e-2)" "unprognostic (1.74e-2)" "unprognostic (1.26e-2)" "unprognostic (3.23e-1)" "unprognostic (2.64e-1)" "unprognostic (4.63e-2)" "unprognostic (1.76e-2)" "unprognostic (1.95e-1)" "unprognostic (4.15e-3)" "unprognostic (2.87e-1)" PAPOLG FLJ12972 ENSG00000115421 "Poly(A) polymerase gamma" Q9BWT3 2 60756253-60802086 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 254769.3;Neurons: 209721.9;Neutrophils: 639351.2" "Tissue enriched" "Detected in single" 222 "intestine: 22229.3" "CAB017795, HPA035349, HPA035350" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 9: T-cells - Adaptive immunity: Regulation" 6 Nucleoplasm "Nuclear bodies, Cytosol" "CAB017795: , HPA035349: , HPA035350: " "unprognostic (1.78e-2)" "unprognostic (1.29e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-1)" "unprognostic (2.88e-3)" "unprognostic (1.13e-2)" "unprognostic (4.96e-1)" "unprognostic (7.27e-2)" "unprognostic (3.86e-2)" "unprognostic (3.40e-2)" "unprognostic (1.71e-2)" "unprognostic (1.76e-1)" "unprognostic (2.85e-2)" "unprognostic (7.18e-2)" "unprognostic (2.78e-1)" "unprognostic (1.87e-1)" "potential prognostic favorable (6.84e-4)" "unprognostic (5.55e-3)" "unprognostic (1.56e-1)" "unprognostic (1.04e-1)" "unprognostic (1.95e-3)" "unprognostic (1.13e-1)" "unprognostic (3.39e-2)" "unprognostic (1.96e-1)" "unprognostic (1.83e-1)" "unprognostic (2.69e-1)" "unprognostic (1.75e-1)" "unprognostic (1.00e-1)" "unprognostic (9.05e-2)" PAPSS1 "ATPSK1, PAPSS" ENSG00000138801 "3'-phosphoadenosine 5'-phosphosulfate synthase 1" O43252 4 107590276-107720234 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 943.6;Endometrial luminal cells: 388.1" "Cell type enhanced" "Detected in all" "Glandular cells: 943.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "basophil: 322.6;eosinophil: 360.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 360.6" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA049781 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome" Yes No 9600 "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 5: Rhabdoid - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 2 "Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA049781: " "unprognostic (1.97e-2)" "unprognostic (9.44e-2)" "unprognostic (1.27e-2)" "unprognostic (1.85e-1)" "unprognostic (1.10e-2)" "unprognostic (3.60e-2)" "unprognostic (5.48e-2)" "unprognostic (9.90e-2)" "unprognostic (1.75e-1)" "unprognostic (7.19e-3)" "potential prognostic favorable (8.10e-5)" "unprognostic (6.87e-3)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (2.45e-7)" "unprognostic (4.02e-2)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (3.02e-1)" "unprognostic (2.30e-1)" "unprognostic (6.73e-2)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (2.23e-1)" "unprognostic (2.93e-1)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (2.23e-1)" "unprognostic (1.31e-1)" "unprognostic (9.25e-2)" "unprognostic (2.25e-2)" "unprognostic (6.58e-2)" PAPSS2 ATPSK2 ENSG00000198682 "3'-phosphoadenosine 5'-phosphosulfate synthase 2" O95340 10 87659613-87747705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Multifunctional enzyme, Nucleotidyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 132.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1065.3;Alveolar cells type 1: 595.0;cDC: 427.1;Colonocytes: 344.5;Enterocytes: 471.6;Hepatocytes: 293.4;Kupffer cells: 260.3;Macrophages: 360.3;monocytes: 493.4;Pancreatic islet cells: 508.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 1065.3;Alveolar cells: 595.0;Enterocytes: 471.6;Mononuclear phagocytes: 493.4;Pancreatic islet cells: 508.5" "Cell type enhanced" "Detected in many" "endothelial cell: 317.7;pericyte: 366.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.0;myeloid DC: 2.1;non-classical monocyte: 7.7" "Group enriched" "Detected in many" 7 "dendritic cells: 2.1;monocytes: 7.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Heart muscle - Endothelial cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Fibroblasts, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 130546028.2;Hepatocytes: 32994508.5" "Tissue enhanced" "Detected in many" "liver: 18648204.3;lung: 15918346.5" "HPA071224, HPA075267" Enhanced Approved Mitochondria No No 9800 "Cluster 40: Monocytes - Innate immune response" "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 Mitochondria "HPA071224: , HPA075267: " "unprognostic (1.62e-1)" "unprognostic (9.66e-3)" "unprognostic (2.85e-1)" "unprognostic (1.94e-2)" "unprognostic (6.57e-2)" "unprognostic (2.09e-2)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (2.58e-2)" "unprognostic (8.82e-2)" "unprognostic (1.28e-2)" "unprognostic (5.19e-2)" "unprognostic (4.66e-2)" "unprognostic (1.19e-2)" "unprognostic (3.98e-1)" "unprognostic (9.32e-3)" "unprognostic (8.03e-3)" "unprognostic (1.71e-2)" "unprognostic (3.79e-1)" "unprognostic (4.53e-2)" "unprognostic (2.62e-2)" "unprognostic (8.39e-3)" "unprognostic (9.19e-2)" "unprognostic (1.20e-1)" "unprognostic (1.94e-1)" "unprognostic (4.68e-3)" "potential prognostic unfavorable (2.85e-5)" "unprognostic (2.39e-3)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (6.10e-5)" "unprognostic (7.58e-3)" PARD3 "ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118" ENSG00000148498 "Par-3 family cell polarity regulator" Q8TEW0 10 34109560-34815325 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2031.3;Podocytes: 2848.1" "Cell type enhanced" "Detected in all" "Renal nephron cells: 2848.1" "Cell type enhanced" "Detected in all" "pericyte: 2229.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 50 "basophil: 9.6" "Lineage enriched" "Detected in single" 96 "granulocytes: 9.6" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "pancreas: 38806262.3" HPA030443 Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 54: Non-specific - Ribosome" "Cluster 46: Brainstem - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 74 "Plasma membrane, Cell Junctions" "HPA030443: " "unprognostic (2.87e-2)" "unprognostic (5.92e-3)" "unprognostic (2.50e-1)" "unprognostic (2.35e-1)" "unprognostic (8.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.74e-2)" "potential prognostic favorable (2.23e-6)" "unprognostic (1.20e-1)" "unprognostic (5.70e-3)" "potential prognostic favorable (9.59e-4)" "unprognostic (2.33e-2)" "unprognostic (2.31e-2)" "validated prognostic unfavorable (1.07e-4)" "validated prognostic unfavorable (8.27e-4)" "unprognostic (1.08e-1)" "unprognostic (1.45e-3)" "unprognostic (1.32e-1)" "unprognostic (3.28e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (2.65e-2)" "unprognostic (1.41e-3)" "unprognostic (2.29e-2)" "unprognostic (1.66e-1)" "unprognostic (1.07e-2)" "unprognostic (2.36e-1)" "unprognostic (3.45e-1)" "unprognostic (5.04e-2)" "unprognostic (2.18e-1)" "unprognostic (1.51e-2)" "unprognostic (2.92e-1)" PARD6A "PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40" ENSG00000102981 "Par-6 family cell polarity regulator alpha" Q9NPB6 16 67660946-67662774 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1;testis: 41.3" "Cell type enriched" "Detected in many" 9 "Late spermatids: 487.2" "Cell type enriched" "Detected in many" 15 "Spermatogenic cell types: 487.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1644 "Astrocytes and Neuropil: 89140.9;Microglia and Neuropil: 201027.5;Neurons: 202979.8" "Tissue enriched" "Detected in single" 203 "cerebral cortex: 20299.5" "CAB009733, HPA041551" Approved Approved "Plasma membrane,Cell Junctions,Actin filaments,Cytosol" No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 30 "Actin filaments" "Plasma membrane, Cell Junctions, Cytosol" "CAB009733: , HPA041551: " "unprognostic (1.37e-2)" "unprognostic (6.03e-3)" "unprognostic (2.14e-2)" "unprognostic (1.68e-1)" "unprognostic (1.92e-2)" "unprognostic (1.13e-1)" "unprognostic (6.88e-2)" "unprognostic (1.60e-2)" "unprognostic (4.76e-3)" "unprognostic (9.84e-2)" "unprognostic (9.24e-3)" "unprognostic (1.27e-2)" "unprognostic (5.35e-3)" "unprognostic (1.67e-3)" "unprognostic (1.89e-2)" "unprognostic (2.14e-1)" "unprognostic (9.85e-2)" "unprognostic (5.59e-2)" "unprognostic (1.64e-1)" "unprognostic (8.89e-2)" "unprognostic (2.27e-1)" "potential prognostic favorable (7.34e-5)" "unprognostic (1.65e-1)" "unprognostic (5.69e-2)" "unprognostic (1.02e-2)" "unprognostic (2.72e-2)" "unprognostic (1.80e-1)" "unprognostic (1.24e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-2)" "unprognostic (3.63e-2)" PARK7 "DJ-1, DJ1, GATD2" ENSG00000116288 "Parkinsonism associated deglycase" Q99497 1 7954291-7985505 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Fertilization, Inflammatory response, Stress response" "Chaperone, Hydrolase, Protease, RNA-binding" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Platelets: 982.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "skeletal muscle: 2093561370.1" "HPA004190, CAB005870" Supported Supported "Nucleoplasm,Cytosol,Flagellar centriole,Mid piece" NA NA 28000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 11: Muller glia cells - Retinal homeostasis" 78 "Nucleoplasm, Cytosol" "Flagellar centriole, Mid piece" "CAB005870: , HPA004190: " "unprognostic (3.42e-2)" "unprognostic (1.90e-1)" "unprognostic (3.44e-3)" "unprognostic (3.25e-3)" "unprognostic (1.86e-2)" "unprognostic (1.64e-1)" "unprognostic (2.54e-2)" "unprognostic (2.28e-1)" "unprognostic (3.73e-3)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (2.98e-3)" "unprognostic (9.71e-2)" "potential prognostic favorable (9.00e-4)" "unprognostic (4.40e-2)" "potential prognostic unfavorable (1.77e-4)" "unprognostic (1.53e-1)" "unprognostic (3.40e-2)" "unprognostic (4.72e-1)" "unprognostic (2.05e-1)" "unprognostic (1.71e-1)" "unprognostic (1.39e-1)" "unprognostic (5.96e-2)" "unprognostic (2.51e-1)" "unprognostic (3.10e-1)" "unprognostic (1.25e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (6.62e-2)" "unprognostic (8.07e-2)" "unprognostic (4.82e-2)" "unprognostic (2.14e-2)" "unprognostic (5.61e-3)" PARP1 "ADPRT, ARTD1, PARP, PARS, Poly-PARP, PPOL" ENSG00000143799 "Poly(ADP-ribose) polymerase 1" P09874 1 226360210-226408154 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Immunity, Innate immunity, Transcription, Transcription regulation" "Allosteric enzyme, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 606.2;Migrating cytotrophoblasts: 329.2" "Cell type enhanced" "Detected in all" "Trophoblast cells: 606.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "B-cells: 613473095.9" "Tissue enhanced" "Detected in all" "lymphoid tissue: 292985496.9" "CAB000147, CAB003839, CAB003840, HPA045168, CAB075726, CAB075727, CAB080368" Supported Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli fibrillar center,Nuclear bodies" NA NA 120000 "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 548 Nucleoplasm "Nucleoli, Nucleoli fibrillar center, Nuclear bodies" "CAB000147: , CAB003839: , CAB003840: , CAB075726: , CAB075727: , CAB080368: , HPA045168: " "unprognostic (2.34e-1)" "unprognostic (3.23e-1)" "unprognostic (3.71e-1)" "unprognostic (2.67e-1)" "unprognostic (1.09e-2)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (1.81e-1)" "unprognostic (1.60e-1)" "unprognostic (3.72e-2)" "unprognostic (1.56e-3)" "unprognostic (5.57e-2)" "unprognostic (6.57e-2)" "unprognostic (1.15e-2)" "unprognostic (3.23e-3)" "unprognostic (6.09e-2)" "unprognostic (1.11e-3)" "unprognostic (4.18e-2)" "unprognostic (7.97e-3)" "unprognostic (3.00e-1)" "unprognostic (1.73e-1)" "unprognostic (1.51e-2)" "unprognostic (4.43e-2)" "unprognostic (3.51e-1)" "unprognostic (2.41e-2)" "unprognostic (1.73e-2)" "unprognostic (1.39e-1)" "unprognostic (1.64e-1)" "unprognostic (2.33e-1)" "unprognostic (2.56e-2)" "unprognostic (4.23e-1)" PARP10 "ARTD10, FLJ14464" ENSG00000178685 "Poly(ADP-ribose) polymerase family member 10" Q53GL7 8 143977153-144012772 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 170.6;Cardiomyocytes: 153.4;Early primary spermatocytes: 95.1;Epicardial cells: 88.7;Proximal tubule cells: 87.9" "Cell type enhanced" "Detected in many" "Adipocytes: 170.6;Myocytes: 153.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 16.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - T-cells" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Macrophages: 13675753.7" "Low tissue specificity" "Detected in many" "HPA028122, HPA052427" Approved Supported "Nucleoli rim,Golgi apparatus,Cytosol" No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 7 "Nucleoli rim" "Golgi apparatus, Cytosol" "HPA028122: , HPA052427: " "unprognostic (1.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.36e-1)" "unprognostic (1.16e-1)" "unprognostic (1.19e-1)" "unprognostic (3.26e-1)" "unprognostic (5.31e-2)" "unprognostic (2.74e-1)" "unprognostic (3.08e-2)" "unprognostic (5.65e-2)" "unprognostic (9.91e-3)" "unprognostic (3.62e-1)" "unprognostic (9.42e-3)" "unprognostic (2.00e-1)" "unprognostic (3.83e-2)" "unprognostic (8.03e-2)" "unprognostic (2.30e-1)" "unprognostic (3.25e-1)" "potential prognostic favorable (1.67e-4)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (4.67e-2)" "unprognostic (1.88e-1)" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (4.13e-3)" "unprognostic (2.09e-2)" "unprognostic (7.76e-2)" "unprognostic (3.84e-2)" PARP12 "ARTD12, FLJ22693, PARP-12, ZC3H1, ZC3HDC1" ENSG00000059378 "Poly(ADP-ribose) polymerase family member 12" Q9H0J9 7 140023749-140062951 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 84.0" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "endothelial cell: 119.0;leukocyte: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 16873572.6" "Low tissue specificity" "Detected in many" "HPA003584, HPA063872" Approved Approved Nucleoplasm NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Nucleoplasm "HPA003584: , HPA063872: " "unprognostic (1.54e-1)" "unprognostic (1.06e-1)" "unprognostic (3.35e-1)" "unprognostic (1.11e-1)" "unprognostic (4.01e-2)" "unprognostic (1.11e-2)" "unprognostic (2.80e-1)" "unprognostic (1.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.80e-2)" "unprognostic (2.67e-2)" "unprognostic (7.94e-2)" "unprognostic (5.58e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (1.17e-1)" "unprognostic (4.68e-2)" "unprognostic (1.77e-2)" "unprognostic (1.10e-1)" "unprognostic (5.23e-2)" "unprognostic (2.03e-1)" "unprognostic (3.78e-2)" "unprognostic (7.77e-3)" "potential prognostic unfavorable (3.86e-4)" "unprognostic (5.28e-1)" "unprognostic (1.10e-1)" "unprognostic (1.92e-2)" "unprognostic (1.81e-2)" "unprognostic (1.59e-1)" "unprognostic (1.65e-1)" "unprognostic (1.97e-1)" "unprognostic (2.32e-3)" PARP14 "ARTD8, BAL2, KIAA1268, pART8" ENSG00000173193 "Poly(ADP-ribose) polymerase family member 14" Q460N5 3 122680839-122730840 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 415.6;B-cells: 251.3;Endometrial luminal cells: 252.6;Transitional alveolar cells: 262.0" "Cell type enhanced" "Detected in all" "Alveolar cells: 415.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 314.3;endothelial cell: 385.0;leukocyte: 183.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 31974793.2;Macrophages: 60643746.4;T-cells: 32897381.6" "Tissue enhanced" "Detected in many" "lymphoid tissue: 28367597.3" "HPA008846, HPA012063" Supported Supported Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 Cytosol "HPA008846: , HPA012063: " "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.23e-1)" "unprognostic (5.27e-2)" "unprognostic (1.57e-1)" "unprognostic (1.18e-1)" "unprognostic (2.55e-1)" "unprognostic (2.73e-1)" "unprognostic (8.12e-2)" "unprognostic (1.33e-2)" "potential prognostic favorable (2.15e-8)" "unprognostic (9.67e-2)" "unprognostic (4.93e-2)" "unprognostic (1.83e-1)" "unprognostic (5.52e-2)" "unprognostic (2.53e-1)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (2.03e-1)" "unprognostic (1.67e-1)" "unprognostic (9.36e-2)" "validated prognostic unfavorable (6.95e-4)" "validated prognostic unfavorable (1.46e-5)" "unprognostic (3.54e-1)" "unprognostic (1.07e-3)" "unprognostic (1.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.40e-1)" "unprognostic (1.19e-1)" "unprognostic (8.68e-2)" "unprognostic (1.31e-1)" PARP2 "ADPRTL2, ARTD2" ENSG00000129484 "Poly(ADP-ribose) polymerase 2" Q9UGN5 14 20343615-20357904 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Allosteric enzyme, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 60.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 104507.0" "Tissue enriched" "Detected in some" "lymphoid tissue: 805767.6" "HPA018137, HPA052003" Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" 20 Nucleoplasm Nucleoli "HPA018137: , HPA052003: " "unprognostic (9.96e-3)" "unprognostic (1.16e-1)" "unprognostic (5.10e-2)" "unprognostic (6.78e-3)" "unprognostic (3.18e-1)" "unprognostic (2.14e-1)" "unprognostic (7.42e-2)" "unprognostic (1.41e-2)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (5.68e-4)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (8.50e-2)" "validated prognostic unfavorable (1.10e-4)" "validated prognostic unfavorable (1.51e-4)" "unprognostic (1.00e-2)" "unprognostic (1.84e-2)" "unprognostic (1.17e-1)" "unprognostic (1.61e-3)" "unprognostic (1.83e-2)" "unprognostic (2.31e-1)" "unprognostic (6.35e-2)" "unprognostic (2.83e-3)" "unprognostic (4.44e-2)" "unprognostic (3.94e-1)" "unprognostic (2.16e-1)" "unprognostic (2.25e-2)" "unprognostic (1.47e-1)" "unprognostic (7.45e-2)" "unprognostic (1.23e-1)" "unprognostic (3.76e-1)" PARP3 "ADPRT3, ADPRTL3, ARTD3, hPARP-3, IRT1, pADPRT-3" ENSG00000041880 "Poly(ADP-ribose) polymerase family member 3" Q9Y6F1 3 51942345-51948867 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 30.7;Foveolar cells: 21.5;Late spermatids: 20.9" "Cell type enhanced" "Detected in many" "Enterocytes: 30.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020984, HPA067657" Supported Supported "Nucleoplasm,Nuclear bodies" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 1: Enterocytes - Absorption and Digestion" 5 "Nucleoplasm, Nuclear bodies" "HPA020984: , HPA067657: " "potential prognostic favorable (8.19e-4)" "unprognostic (1.18e-3)" "unprognostic (2.30e-2)" "unprognostic (2.42e-1)" "unprognostic (1.24e-1)" "unprognostic (3.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.89e-2)" "unprognostic (1.26e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (1.85e-1)" "potential prognostic favorable (5.91e-8)" "unprognostic (5.75e-2)" "unprognostic (1.39e-3)" "unprognostic (3.45e-2)" "unprognostic (5.22e-2)" "unprognostic (1.61e-2)" "unprognostic (1.54e-1)" "unprognostic (8.89e-2)" "unprognostic (9.98e-2)" "unprognostic (1.61e-3)" "unprognostic (2.30e-1)" "unprognostic (4.30e-1)" "unprognostic (5.67e-2)" "unprognostic (2.17e-2)" "unprognostic (2.78e-1)" "unprognostic (1.35e-1)" "unprognostic (2.85e-1)" "unprognostic (3.21e-2)" "unprognostic (8.41e-3)" PARP4 "ADPRTL1, ARTD4, p193, VAULT3, VPARP, VWA5C" ENSG00000102699 "Poly(ADP-ribose) polymerase family member 4" Q9UKK3 13 24420931-24512778 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Ribonucleoprotein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Mast cells: 338.6;Neutrophil progenitors: 350.1;Neutrophils: 656.7" "Cell type enhanced" "Detected in many" "Neutrophils: 656.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 170.8;leukocyte: 162.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 32174126.8;Proximal tubules: 26372497.2" "Low tissue specificity" "Detected in many" HPA011739 Approved Supported "Nucleoplasm,Microtubules,Mitotic spindle,Primary cilium,Cytosol" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 30: White matter - Myelination" "Cluster 19: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "Nucleoplasm, Microtubules, Cytosol" "Mitotic spindle, Primary cilium" "HPA011739: " "unprognostic (2.32e-1)" "unprognostic (2.02e-1)" "unprognostic (3.35e-1)" "unprognostic (1.06e-2)" "unprognostic (1.94e-1)" "unprognostic (3.90e-2)" "unprognostic (3.39e-1)" "unprognostic (1.10e-2)" "unprognostic (3.00e-1)" "unprognostic (2.55e-2)" "potential prognostic favorable (1.47e-7)" "unprognostic (2.20e-2)" "unprognostic (1.10e-2)" "unprognostic (8.04e-2)" "unprognostic (1.15e-2)" "unprognostic (6.54e-2)" "unprognostic (3.30e-3)" "unprognostic (7.73e-2)" "unprognostic (2.16e-1)" "unprognostic (2.94e-3)" "unprognostic (5.88e-3)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (1.79e-1)" "unprognostic (5.67e-2)" "unprognostic (4.81e-3)" "unprognostic (7.13e-2)" "unprognostic (1.65e-1)" "unprognostic (7.76e-2)" "unprognostic (3.22e-1)" "unprognostic (6.48e-2)" "unprognostic (2.09e-1)" PARP6 "ARTD17, pART17" ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 310.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 310.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA026991 Approved Approved "Plasma membrane" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Plasma membrane" "HPA026991: " "unprognostic (2.52e-1)" "unprognostic (2.15e-1)" "unprognostic (6.11e-2)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (7.07e-4)" "unprognostic (3.35e-2)" "unprognostic (1.22e-1)" "unprognostic (1.33e-3)" "unprognostic (6.58e-2)" "unprognostic (9.71e-3)" "unprognostic (2.02e-3)" "unprognostic (5.04e-3)" "unprognostic (2.42e-1)" "unprognostic (2.02e-2)" "unprognostic (1.95e-2)" "unprognostic (1.16e-1)" "unprognostic (5.07e-2)" "unprognostic (1.68e-1)" "unprognostic (7.33e-3)" "unprognostic (8.40e-2)" "unprognostic (5.16e-3)" "unprognostic (1.19e-2)" "unprognostic (7.58e-3)" "unprognostic (2.61e-2)" "unprognostic (9.84e-2)" "unprognostic (8.22e-2)" "unprognostic (9.86e-2)" "unprognostic (8.90e-2)" "unprognostic (1.14e-1)" "unprognostic (7.41e-2)" "unprognostic (5.52e-3)" PARP8 "ARTD16, FLJ21308, pART16" ENSG00000151883 "Poly(ADP-ribose) polymerase family member 8" Q8N3A8 5 50665899-50846519 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 81.6" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 612.5;Neutrophil progenitors: 717.1;Neutrophils: 1886.6;NK-cells: 1462.3;T-cells: 1713.9" "Cell type enhanced" "Detected in many" "Neutrophils: 1886.6;NK-cells: 1462.3;T-cells: 1713.9" "Cell type enhanced" "Detected in all" "leukocyte: 1862.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 15230 "intestine: 1522969.7" HPA049183 Approved Approved "Nucleoplasm,Midbody ring,Cytosol" Yes No "Cluster 1: T-cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 Nucleoplasm "Midbody ring, Cytosol" "HPA049183: " "unprognostic (2.40e-1)" "unprognostic (2.86e-2)" "unprognostic (1.00e-1)" "unprognostic (2.46e-1)" "unprognostic (2.90e-1)" "unprognostic (2.99e-1)" "unprognostic (1.63e-1)" "unprognostic (6.21e-3)" "unprognostic (1.75e-2)" "unprognostic (2.16e-1)" "unprognostic (1.44e-1)" "unprognostic (2.09e-1)" "unprognostic (2.00e-2)" "unprognostic (8.36e-2)" "unprognostic (9.49e-2)" "unprognostic (2.01e-3)" "unprognostic (4.70e-2)" "unprognostic (3.49e-3)" "unprognostic (3.38e-1)" "unprognostic (3.97e-2)" "unprognostic (3.27e-1)" "unprognostic (1.81e-1)" "unprognostic (1.31e-2)" "unprognostic (3.70e-2)" "unprognostic (2.03e-2)" "unprognostic (3.48e-2)" "unprognostic (2.97e-1)" "unprognostic (2.34e-2)" "unprognostic (3.02e-1)" "unprognostic (9.15e-2)" "unprognostic (1.13e-1)" PARS2 DKFZp727A071 ENSG00000162396 "Prolyl-tRNA synthetase 2, mitochondrial" Q7L3T8 1 54756898-54764523 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 16.0;Late primary spermatocytes: 13.1;Retinal horizontal cells: 16.0" "Cell type enhanced" "Detected in many" "Neuronal cells: 16.0;Spermatogenic cell types: 16.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 15409258.9;Large ducts: 15975536.1" "Low tissue specificity" "Detected in all" "HPA028308, HPA028314, HPA028518" Uncertain Approved "Nucleoli fibrillar center,Mitochondria" No No "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 13 "Nucleoli fibrillar center, Mitochondria" "HPA028308: , HPA028314: , HPA028518: " "unprognostic (1.23e-1)" "unprognostic (1.45e-1)" "unprognostic (1.31e-1)" "unprognostic (5.49e-2)" "unprognostic (1.29e-3)" "unprognostic (1.28e-1)" "unprognostic (2.60e-2)" "unprognostic (1.20e-2)" "unprognostic (2.06e-3)" "unprognostic (5.37e-3)" "validated prognostic favorable (3.68e-7)" "validated prognostic favorable (8.90e-4)" "unprognostic (5.97e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (5.78e-3)" "unprognostic (7.12e-2)" "unprognostic (7.32e-3)" "unprognostic (3.11e-1)" "unprognostic (1.32e-2)" "unprognostic (9.16e-2)" "unprognostic (1.81e-1)" "unprognostic (9.07e-2)" "unprognostic (3.05e-3)" "unprognostic (8.99e-2)" "potential prognostic favorable (2.74e-5)" "unprognostic (3.51e-2)" "unprognostic (3.46e-1)" "unprognostic (6.90e-2)" "unprognostic (1.55e-1)" "unprognostic (1.49e-1)" "unprognostic (4.57e-1)" PATJ "Cipp, INADL" ENSG00000132849 "PATJ crumbs cell polarity complex component" Q8NI35 1 61742477-62178675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubule cells: 1347.0" "Cell type enhanced" "Detected in all" "Renal nephron cells: 1347.0" "Cell type enhanced" "Detected in all" "upper rhombic lip: 969.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 161.2" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 93.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 20223885.2" "Group enriched" "Detected in many" "intestine: 14694819.0;lung: 3704901.7" "HPA066352, HPA066960, HPA069079" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 16 "Cell Junctions" "Centriolar satellite, Cytosol" "HPA066352: , HPA066960: , HPA069079: " "unprognostic (2.76e-3)" "unprognostic (2.93e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (3.12e-1)" "unprognostic (4.59e-1)" "unprognostic (2.10e-1)" "unprognostic (9.60e-3)" "unprognostic (6.40e-2)" "unprognostic (5.91e-2)" "validated prognostic favorable (1.46e-5)" "validated prognostic favorable (2.34e-4)" "unprognostic (1.45e-1)" "unprognostic (2.43e-3)" "unprognostic (1.73e-1)" "unprognostic (5.82e-3)" "unprognostic (1.02e-1)" "unprognostic (2.15e-1)" "unprognostic (1.18e-1)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (3.89e-4)" "unprognostic (1.26e-1)" "unprognostic (5.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (5.03e-2)" "potential prognostic favorable (9.95e-4)" "unprognostic (9.75e-3)" "unprognostic (8.67e-2)" "unprognostic (1.08e-1)" PATZ1 "dJ400N23, MAZR, PATZ, RIAZ, ZBTB19, ZNF278, ZSG" ENSG00000100105 "POZ/BTB and AT hook containing zinc finger 1" Q9HBE1 22 31325804-31346346 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Spleen - B-cells (Spleen), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 76861.7;Granulosa cells: 79758.0" "Group enriched" "Detected in some" 389 "lymphoid tissue: 40384.6;ovary: 37371.8" "HPA047893, HPA048315" Approved Supported Nucleoplasm No No "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 4: Breast lactating luminal cells - Lactation" 7 Nucleoplasm "HPA047893: , HPA048315: " "unprognostic (2.12e-2)" "unprognostic (9.28e-2)" "unprognostic (4.14e-1)" "unprognostic (9.04e-2)" "unprognostic (3.26e-1)" "unprognostic (2.04e-1)" "unprognostic (4.19e-2)" "unprognostic (2.28e-3)" "unprognostic (2.01e-1)" "unprognostic (2.26e-1)" "validated prognostic favorable (1.86e-7)" "validated prognostic favorable (5.25e-4)" "unprognostic (6.03e-3)" "unprognostic (1.55e-2)" "unprognostic (5.58e-3)" "unprognostic (2.00e-1)" "unprognostic (2.74e-1)" "unprognostic (5.77e-3)" "potential prognostic favorable (1.16e-4)" "unprognostic (3.49e-1)" "unprognostic (3.47e-1)" "unprognostic (1.76e-1)" "unprognostic (1.12e-1)" "unprognostic (2.56e-1)" "unprognostic (1.31e-3)" "unprognostic (2.26e-1)" "unprognostic (1.41e-1)" "unprognostic (1.42e-1)" "unprognostic (1.45e-1)" "unprognostic (1.02e-1)" "unprognostic (4.12e-2)" PAX2 PAX-2 ENSG00000075891 "Paired box 2" Q02962 10 100735396-100829944 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "epididymis: 28.0;kidney: 94.2" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 142.0;Endometrial glandular cells: 152.3;Endometrial luminal cells: 543.6;Epididymal principal cells: 335.6;Loop of henle epithelial cells: 340.7;Papillary tip epithelial cells: 181.5;Proximal tubule cells: 296.5;Renal collecting duct intercalated cells: 243.5;Renal collecting duct principal cells: 537.7;Renal connecting tubule cells: 327.3" "Group enriched" "Detected in many" 7 "Ductal cells: 537.7;Glandular cells: 152.3;Luminal cells: 543.6;Renal nephron cells: 340.7;Reproductive supporting cells: 335.6" "Cell type enriched" "Detected in some" 6 "cerebellar inhibitory: 82.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 30.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 68.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Kidney cancer: 17.9;ovarian cancer: 5.4;Rhabdoid: 10.8;Uterine cancer: 8.5" "Group enriched" "Detected in some" 9 "cerebellum: 1.3;pons and medulla: 3.4" "Group enriched" "Detected in some" 6 "cerebellum: 5.2;medulla oblongata: 7.7;spinal cord: 6.9" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013024, HPA047704, HPA070751" Enhanced Supported Nucleoplasm "Intracellular and membrane" "Developmental protein" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 43: Hindbrain - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 3 Nucleoplasm "CAB013024: , HPA047704: , HPA070751: " "unprognostic (5.51e-2)" "unprognostic (7.96e-2)" "potential prognostic favorable (6.48e-4)" "potential prognostic favorable (1.19e-4)" "unprognostic (1.37e-2)" "unprognostic (7.08e-2)" "unprognostic (2.07e-2)" "unprognostic (5.85e-2)" "unprognostic (8.76e-2)" "unprognostic (4.67e-2)" PBX1 ENSG00000185630 "PBX homeobox 1" P40424 1 164555584-164899296 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Sexual differentiation, Steroidogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pituitary stem cells: 1944.2" "Cell type enhanced" "Detected in all" "Stem cells: 1944.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Distal tubules: 6969529.8;Fallopian tube cells: 5995957.7;Large ducts: 1989589.6" "Group enriched" "Detected in many" "fallopian tube: 3982248.5;ovary: 2196954.0" "HPA003505, HPA003881, CAB018768" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 105: Non-specific - Mixed function" 30 Nucleoplasm "Nuclear bodies, Cytosol" "CAB018768: , HPA003505: , HPA003881: " "potential prognostic favorable (7.04e-5)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "unprognostic (1.31e-1)" "unprognostic (1.59e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-2)" "unprognostic (1.70e-1)" "unprognostic (5.22e-3)" "unprognostic (1.01e-2)" "validated prognostic favorable (1.08e-5)" "validated prognostic favorable (5.97e-5)" "unprognostic (8.21e-3)" "unprognostic (1.52e-1)" "unprognostic (6.65e-2)" "unprognostic (4.58e-1)" "unprognostic (1.71e-1)" "unprognostic (1.06e-1)" "unprognostic (4.53e-2)" "unprognostic (1.60e-1)" "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "unprognostic (1.04e-1)" "unprognostic (2.27e-1)" "unprognostic (2.35e-1)" "unprognostic (2.03e-1)" "unprognostic (1.21e-1)" "unprognostic (1.15e-1)" "unprognostic (5.47e-2)" "unprognostic (1.33e-1)" "unprognostic (1.69e-1)" PBX3 ENSG00000167081 "PBX homeobox 3" P40426 9 125747345-125967377 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 144.0" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 709.4;Cone photoreceptor cells: 507.2" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 1632.7" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 93.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 14.0" "Lineage enriched" "Detected in all" 4 "dendritic cells: 14.0" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Region enhanced" "Detected in all" "olfactory bulb: 167.4" "Group enriched" "Detected in all" 5 "basal ganglia: 56.8;olfactory bulb: 199.8" "Cell type enriched" "Detected in single" 1466 "Pancreatic islets: 146581.4" "Not detected" "Not detected" HPA003881 Supported Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Nucleoplasm "Nuclear bodies, Cytosol" "HPA003881: " "unprognostic (6.00e-2)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (8.18e-2)" "unprognostic (1.19e-2)" "unprognostic (3.85e-3)" "unprognostic (2.87e-1)" "unprognostic (7.10e-2)" "unprognostic (1.05e-1)" "unprognostic (1.26e-1)" "unprognostic (2.06e-3)" "unprognostic (1.59e-1)" "unprognostic (6.05e-2)" "unprognostic (1.55e-1)" "unprognostic (1.74e-1)" "unprognostic (1.80e-1)" "unprognostic (1.62e-2)" "unprognostic (4.64e-3)" "unprognostic (1.18e-1)" "unprognostic (1.51e-1)" "unprognostic (2.72e-2)" "unprognostic (1.62e-2)" "unprognostic (1.73e-1)" "unprognostic (5.62e-2)" "unprognostic (1.05e-2)" "unprognostic (8.45e-2)" "unprognostic (1.84e-1)" "unprognostic (2.15e-2)" "unprognostic (3.27e-1)" "unprognostic (9.33e-2)" "unprognostic (1.10e-1)" PC PCB ENSG00000173599 "Pyruvate carboxylase" P11498 11 66848417-66958386 "Citric acid cycle related proteins, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Lipid biosynthesis, Lipid metabolism" "Ligase, Multifunctional enzyme" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 182.1" "Cell type enhanced" "Detected in many" "Adipocytes: 252.6;Hepatocytes: 250.1;Lacrimal acinar cells: 97.8;Late spermatids: 89.6;Proximal tubule cells: 104.2" "Cell type enhanced" "Detected in many" "Adipocytes: 252.6;Hepatocytes: 250.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 63.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 585381310.2;Proximal tubules: 994076096.3" "Tissue enriched" "Detected in all" "liver: 427880240.8" "CAB033742, HPA043922, HPA058765, HPA070392" Enhanced Enhanced Mitochondria Yes No 180000 "Cluster 13: Non-specific - Mitochondria" "Cluster 36: Brain & Liver - Signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 14 Mitochondria "CAB033742: , HPA043922: , HPA058765: , HPA070392: " "unprognostic (1.41e-2)" "unprognostic (1.71e-1)" "unprognostic (1.11e-2)" "unprognostic (1.64e-2)" "potential prognostic favorable (8.68e-4)" "unprognostic (3.58e-2)" "unprognostic (3.44e-1)" "unprognostic (4.42e-3)" "unprognostic (1.13e-1)" "unprognostic (1.71e-2)" "potential prognostic favorable (6.67e-7)" "unprognostic (2.27e-1)" "unprognostic (2.24e-3)" "unprognostic (3.24e-1)" "unprognostic (7.21e-3)" "unprognostic (1.18e-1)" "unprognostic (3.38e-3)" "unprognostic (6.52e-2)" "unprognostic (3.78e-2)" "potential prognostic unfavorable (5.97e-4)" "unprognostic (1.67e-1)" "unprognostic (1.49e-1)" "unprognostic (3.06e-2)" "unprognostic (8.20e-2)" "unprognostic (8.91e-2)" "unprognostic (2.21e-1)" "unprognostic (5.13e-1)" "unprognostic (5.21e-2)" "unprognostic (4.11e-1)" "unprognostic (1.66e-2)" "unprognostic (1.23e-3)" PCBD1 "DCOH, PCBD, PCD" ENSG00000166228 "Pterin-4 alpha-carbinolamine dehydratase 1" P61457 10 70882280-70888565 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis, Transcription, Transcription regulation" "Activator, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 488.2" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 416.2;Gastric progenitor cells: 325.5;Hepatocytes: 604.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 604.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 87725377.4" "Tissue enhanced" "Detected in all" "liver: 1521541164.9" "HPA037575, HPA061723" Enhanced Enhanced Nucleoplasm,Cytosol NA NA 540000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 26 Nucleoplasm Cytosol "HPA037575: , HPA061723: " "unprognostic (6.80e-3)" "unprognostic (2.35e-2)" "unprognostic (3.68e-1)" "unprognostic (6.28e-3)" "unprognostic (1.50e-1)" "unprognostic (1.18e-2)" "unprognostic (5.59e-3)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.59e-2)" "unprognostic (3.69e-2)" "unprognostic (9.65e-3)" "unprognostic (6.90e-3)" "unprognostic (1.04e-1)" "unprognostic (4.74e-2)" "unprognostic (1.84e-1)" "unprognostic (8.32e-2)" "unprognostic (4.15e-2)" "unprognostic (3.35e-2)" "unprognostic (1.56e-1)" "unprognostic (2.03e-1)" "unprognostic (1.47e-1)" "unprognostic (2.82e-1)" "unprognostic (3.72e-2)" "unprognostic (1.72e-1)" "unprognostic (1.65e-2)" "unprognostic (1.43e-1)" "unprognostic (4.36e-2)" "unprognostic (1.90e-1)" "unprognostic (5.17e-2)" "unprognostic (4.60e-2)" PCBP1 "hnRNP-E1, hnRNP-X, HNRPE1, HNRPX" ENSG00000169564 "Poly(rC) binding protein 1" Q15365 2 70087477-70089203 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Viral RNA replication" "DNA-binding, Ribonucleoprotein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1253.8;Syncytiotrophoblasts: 804.4" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1253.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB037113, HPA043803, HPA068497" Approved Supported "Nucleoplasm,Nuclear speckles,Cytosol,Cytoplasmic bodies" No No 2700000 "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 111 "Nuclear speckles" "Nucleoplasm, Cytosol, Cytoplasmic bodies" "CAB037113: , HPA043803: , HPA068497: " "unprognostic (2.51e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (2.20e-2)" "unprognostic (2.15e-1)" "unprognostic (2.98e-1)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (9.99e-4)" "unprognostic (1.09e-2)" "unprognostic (3.37e-1)" "potential prognostic favorable (1.48e-9)" "unprognostic (1.51e-3)" "unprognostic (1.02e-1)" "unprognostic (6.47e-3)" "unprognostic (6.82e-3)" "potential prognostic unfavorable (7.88e-4)" "unprognostic (8.52e-2)" "unprognostic (7.72e-2)" "unprognostic (1.88e-2)" "unprognostic (1.36e-1)" "unprognostic (1.97e-2)" "unprognostic (2.21e-2)" "unprognostic (4.36e-3)" "unprognostic (1.17e-1)" "unprognostic (2.18e-1)" "unprognostic (1.08e-1)" "unprognostic (1.48e-1)" "unprognostic (1.68e-1)" "unprognostic (4.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.67e-1)" PCBP3 "FLJ44028, PCBP3-OT1, PCBP3OT" ENSG00000183570 "Poly(rC) binding protein 3" P57721 21 45643694-45942454 "Plasma proteins, Predicted intracellular proteins" "DNA-binding, Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 59.3;retina: 75.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 1289.7;Corticotrophs: 568.8;Early primary spermatocytes: 415.8;Retinal amacrine cells: 402.2;Retinal bipolar cells: 741.8;Retinal ganglion cells: 633.5;Retinal horizontal cells: 414.7;Rod photoreceptor cells: 1187.2;Thymocytes: 418.4" "Cell type enhanced" "Detected in many" "Neuronal cells: 1289.7;Pituitary endocrine cells: 568.8;Spermatogenic cell types: 415.8;T-cells: 418.4" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 1029.0;pericyte: 591.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.0" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 37.3" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in all" 5 "olfactory bulb: 229.2" "Region enhanced" "Detected in all" "olfactory bulb: 111.2" "Group enriched" "Detected in some" "Neurons: 3292363.9;Oocytes: 928173.4" "Group enriched" "Detected in some" 336 "bone marrow: 15547.7;cerebral cortex: 28860.5;intestine: 28738.3;lymphoid tissue: 61138.8" "HPA030247, HPA073145" Approved Uncertain Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 7 "Nucleoplasm, Mitochondria" Vesicles "HPA030247: , HPA073145: " "unprognostic (2.63e-2)" "unprognostic (2.08e-3)" "potential prognostic unfavorable (3.44e-4)" "unprognostic (2.02e-3)" "unprognostic (2.44e-1)" "unprognostic (1.28e-2)" "unprognostic (1.70e-1)" "unprognostic (6.47e-2)" "validated prognostic unfavorable (7.00e-7)" "validated prognostic unfavorable (8.45e-4)" "unprognostic (1.93e-3)" "unprognostic (1.90e-2)" "unprognostic (6.11e-2)" "unprognostic (4.86e-3)" "unprognostic (1.22e-1)" "unprognostic (1.27e-3)" "potential prognostic favorable (2.99e-4)" "unprognostic (3.80e-1)" "unprognostic (4.04e-2)" "unprognostic (2.24e-2)" "unprognostic (1.65e-3)" "unprognostic (4.62e-2)" "unprognostic (3.61e-2)" "unprognostic (3.71e-2)" "unprognostic (4.27e-3)" PCCA ENSG00000175198 "Propionyl-CoA carboxylase subunit alpha" P05165 13 100089015-100530437 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Ligase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 206.3" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 837.4;Distal convoluted tubule cells: 879.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubules: 538793952.1;Proximal tubules: 426296896.7" "Low tissue specificity" "Detected in all" "HPA041716, HPA047792" Enhanced Supported Mitochondria NA NA 300000 "Cluster 33: Non-specific - ATP binding" "Cluster 22: Epididymis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 8 Mitochondria "HPA041716: , HPA047792: " "unprognostic (6.74e-2)" "unprognostic (8.69e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-2)" "unprognostic (9.14e-2)" "unprognostic (2.01e-2)" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" "unprognostic (5.54e-2)" "validated prognostic favorable (2.50e-9)" "validated prognostic favorable (1.02e-4)" "potential prognostic favorable (5.51e-8)" "unprognostic (2.01e-1)" "unprognostic (9.22e-3)" "unprognostic (5.30e-2)" "unprognostic (1.77e-1)" "unprognostic (6.48e-2)" "unprognostic (1.09e-1)" "unprognostic (1.29e-1)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.93e-1)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (4.96e-2)" "unprognostic (1.82e-2)" "unprognostic (3.41e-2)" "unprognostic (4.92e-3)" "unprognostic (1.59e-1)" "unprognostic (4.54e-3)" PCDH10 "KIAA1400, OL-PCDH" ENSG00000138650 "Protocadherin 10" Q9P2E7 4 133149294-133208606 "Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 19.1;brain: 35.0;placenta: 24.3;prostate: 10.0;seminal vesicle: 16.3" "Cell type enhanced" "Detected in many" "Astrocytes: 74.6;Brain excitatory neurons: 39.7;Brain inhibitory neurons: 108.7;Corticotrophs: 44.3;Endometrial luminal cells: 85.2;Epididymal efferent duct absorptive cells: 131.8;Epididymal efferent duct ciliated cells: 42.8;Oligodendrocyte progenitor cells: 69.0;Oligodendrocytes: 121.6;Other brain neurons: 79.4;Schwann cells: 41.1" "Cell type enhanced" "Detected in many" "Ductal cells: 131.8;Glial cells: 121.6;Luminal cells: 85.2;Neuronal cells: 108.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 18.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 44.4" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27205 "Astrocytes and Neuropil: 3327713.6;Microglia and Neuropil: 2774697.9;Neurons: 2059133.6" "Group enriched" "Detected in some" "cerebral cortex: 15463216.9;kidney: 7903084.6;liver: 4129949.7" "HPA011220, HPA073462" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA 21000 "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" 7 "Golgi apparatus" "Nucleoplasm, Vesicles" "HPA011220: , HPA073462: " "unprognostic (1.96e-1)" "unprognostic (2.27e-1)" "unprognostic (1.65e-1)" "unprognostic (8.17e-2)" "unprognostic (2.42e-3)" "unprognostic (1.17e-2)" "unprognostic (4.77e-3)" "unprognostic (1.20e-1)" "unprognostic (5.48e-2)" "unprognostic (8.50e-2)" PCDH18 "KIAA1562, PCDH68L" ENSG00000189184 "Protocadherin 18" Q9HCL0 4 137518918-137532494 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 59.4;Decidual stromal cells: 28.0;Endometrial stromal cells: 65.1;Fibro-adipogenic progenitors: 31.4;Fibroblasts: 72.3;Hepatic stellate cells: 19.4;Leydig cells: 40.0;Pericytes: 48.3;Peritubular myoid cells: 62.6;Retinal pigment epithelial cells: 106.6;Vascular smooth muscle cells: 24.9" "Cell type enhanced" "Detected in many" "Adipocytes: 59.4;Fibroblasts: 72.3;Leydig cells: 40.0;Mural cells: 48.3;Pigment cells: 106.6;Stromal cells: 65.1" "Cell type enhanced" "Detected in many" "fibroblast: 46.6;pericyte: 123.4;vascular associated smooth muscle cell: 50.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 22.0;testis cancer: 35.3" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in many" "skin: 1717664.5" HPA017976 Approved Approved "Golgi apparatus,Cytosol" No NA 8700000 "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 1 Cytosol "Golgi apparatus" "HPA017976: " "unprognostic (6.38e-2)" "unprognostic (3.65e-1)" "unprognostic (2.61e-1)" "unprognostic (1.15e-1)" "unprognostic (6.32e-2)" "unprognostic (3.96e-2)" "unprognostic (2.68e-1)" "unprognostic (2.20e-1)" "unprognostic (1.48e-2)" "unprognostic (1.37e-1)" "unprognostic (2.61e-2)" "unprognostic (1.89e-3)" "unprognostic (4.05e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-2)" "unprognostic (3.04e-1)" "unprognostic (1.50e-1)" "unprognostic (8.58e-2)" "unprognostic (5.91e-2)" "unprognostic (3.00e-1)" "unprognostic (2.66e-1)" "unprognostic (1.05e-1)" "unprognostic (4.81e-2)" "unprognostic (4.26e-3)" "potential prognostic unfavorable (6.75e-4)" "unprognostic (4.74e-2)" "unprognostic (3.09e-1)" "unprognostic (1.61e-1)" PCDH20 "FLJ22218, PCDH13" ENSG00000280165 "Protocadherin 20" Q8N6Y1 13 61409685-61415849 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.8;smooth muscle: 7.8" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 14.2;Brain inhibitory neurons: 9.1;Oligodendrocyte progenitor cells: 45.5;Oligodendrocytes: 3.1;Other brain neurons: 9.0;Paneth cells: 3.9" "Group enriched" "Detected in some" 7 "Glial cells: 45.5;Neuronal cells: 14.2" "Cell type enhanced" "Detected in many" "hippocampal CA4: 66.8;hippocampal dentate gyrus: 75.1;oligodendrocyte precursor cell: 47.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 3.8;Kidney cancer: 4.6" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Neurons: 159203.3" "Not detected" "Not detected" HPA062669 Approved "Vesicles,Cytokinetic bridge" Yes NA 6500 "Cluster 73: Brain - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 Vesicles "Cytokinetic bridge" "HPA062669: " "unprognostic (3.93e-1)" "unprognostic (1.08e-1)" "unprognostic (1.62e-1)" "unprognostic (4.13e-1)" "unprognostic (1.96e-1)" "unprognostic (8.04e-2)" "unprognostic (7.11e-3)" "unprognostic (7.82e-2)" "unprognostic (3.90e-1)" "unprognostic (5.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.57e-2)" "unprognostic (1.89e-2)" PCDHA12 PCDH-ALPHA12 ENSG00000251664 "Protocadherin alpha 12" Q9UN75 5 140875302-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.6;lung: 1.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1.0;Cholangiocytes: 2.0;Late spermatids: 1.6" "Cell type enhanced" "Detected in some" "Alveolar cells: 1.0;Ductal cells: 2.0;Spermatogenic cell types: 1.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Adrenal gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA035812 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Plasma membrane, Cytosol" "HPA035812: " "unprognostic (6.84e-2)" "unprognostic (2.25e-1)" "unprognostic (7.64e-3)" "unprognostic (3.35e-2)" "unprognostic (2.71e-1)" "unprognostic (6.29e-2)" "unprognostic (2.08e-1)" "unprognostic (1.02e-1)" "unprognostic (2.29e-2)" "unprognostic (1.54e-1)" "unprognostic (1.39e-2)" PCDHA2 ENSG00000204969 "Protocadherin alpha 2" Q9Y5H9 5 140794852-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.1;pituitary gland: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in single" "Bergmann glia: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA035653 Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" 2 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA035653: " "unprognostic (9.70e-2)" "unprognostic (1.51e-1)" "unprognostic (2.59e-2)" PCDHA8 ENSG00000204962 "Protocadherin alpha 8" Q9Y5H6 5 140841187-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.3" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA044585 Uncertain Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 35: Non-specific - DNA binding" "Cluster 10: Ciliated cells - Ion channel activity" "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle, Primary cilium" "HPA044585: " "unprognostic (5.71e-2)" "unprognostic (1.12e-1)" PCDHAC1 ENSG00000248383 "Protocadherin alpha subfamily C, 1" Q9H158 5 140926299-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "parathyroid gland: 28.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Lung Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.2;Rhabdoid: 3.4" "Colon - Colon enteroendocrine cells, Lung - Alveolar cells type 2, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Microglia and Neuropil: 1067115.1" "Not detected" "Not detected" HPA052775 Approved Nucleoplasm,Nucleoli,Vesicles No No "Cluster 69: Parathyroid gland - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Nucleoplasm, Nucleoli" Vesicles "HPA052775: " "unprognostic (1.49e-1)" "unprognostic (5.23e-3)" "unprognostic (1.15e-1)" "unprognostic (1.05e-3)" "unprognostic (1.45e-1)" "unprognostic (1.48e-1)" PCDHB14 PCDH-BETA14 ENSG00000120327 "Protocadherin beta 14" Q9Y5E9 5 141223343-141227759 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Astrocytes: 12.3;Bergmann glia: 11.9;Brain excitatory neurons: 11.5;Brain inhibitory neurons: 13.9;Ependymal cells: 10.1;Oligodendrocyte progenitor cells: 9.8;Oligodendrocytes: 4.9;Other brain neurons: 6.0;Podocytes: 4.1" "Group enriched" "Detected in some" 11 "Ciliated cells: 10.1;Glial cells: 12.3;Neuronal cells: 13.9;Renal nephron cells: 4.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 10.8" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Fibroblasts, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 282 "Microglia and Neuropil: 28174.5" "Tissue enriched" "Detected in single" 9228 "cerebral cortex: 922816.2" "HPA007692, HPA045248" Uncertain Approved Vesicles NA NA 31000 "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 15 Vesicles "HPA007692: , HPA045248: " "unprognostic (3.46e-1)" "unprognostic (3.99e-2)" "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (4.63e-2)" "unprognostic (2.33e-2)" "unprognostic (1.37e-2)" "unprognostic (1.77e-1)" "unprognostic (1.52e-2)" "unprognostic (3.10e-1)" "unprognostic (8.37e-3)" "unprognostic (7.33e-2)" "unprognostic (2.80e-1)" "unprognostic (1.20e-2)" "unprognostic (2.27e-2)" "unprognostic (2.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.01e-1)" "unprognostic (2.23e-2)" "unprognostic (4.23e-2)" "unprognostic (2.00e-1)" "unprognostic (6.60e-2)" "unprognostic (1.27e-1)" "unprognostic (1.93e-2)" "unprognostic (2.86e-2)" "unprognostic (8.38e-2)" "unprognostic (4.05e-2)" "unprognostic (2.17e-1)" "unprognostic (7.06e-2)" "unprognostic (5.27e-2)" "unprognostic (3.00e-2)" PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 "Protocadherin gamma subfamily A, 1" Q9Y5H4 5 141330514-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Cardiomyocytes: 13.2;Corticotrophs: 24.2;Lactotrophs: 21.0;Myonuclei: 9.0;Pituitary stem cells: 10.3;Sertoli cells: 13.7;Somatotrophs: 14.0;Thymic myoid cells: 6.8;Thyrotrophs: 19.6" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 10.6;Myocytes: 13.2;Pituitary endocrine cells: 24.2;Reproductive supporting cells: 13.7;Stem cells: 10.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580, HPA036547" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: , HPA036547: " "unprognostic (1.46e-1)" "unprognostic (4.74e-1)" "unprognostic (1.93e-1)" "unprognostic (3.22e-3)" "unprognostic (4.01e-1)" "unprognostic (2.03e-3)" "unprognostic (3.97e-3)" "unprognostic (1.23e-1)" "unprognostic (5.68e-3)" PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 14.9" "Group enriched" "Detected in some" 5 "Astrocytes: 30.1;Bergmann glia: 39.3;Brain excitatory neurons: 19.2;Brain inhibitory neurons: 16.0;Choroid plexus epithelial cells: 14.1;Ependymal cells: 12.5;Oligodendrocyte progenitor cells: 25.3;Oligodendrocytes: 10.0;Other brain neurons: 13.5" "Group enriched" "Detected in some" 20 "Ciliated cells: 14.1;Glial cells: 39.3;Neuronal cells: 19.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580, HPA077276" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 30000 "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 5 "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: , HPA010580: , HPA077276: " "unprognostic (3.44e-2)" "unprognostic (2.06e-1)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (2.85e-1)" "unprognostic (7.05e-2)" "unprognostic (3.73e-2)" "unprognostic (1.15e-1)" "unprognostic (3.34e-2)" "unprognostic (5.47e-2)" "unprognostic (7.08e-3)" "unprognostic (6.85e-2)" "unprognostic (1.39e-2)" "unprognostic (1.93e-1)" "unprognostic (2.11e-1)" "unprognostic (7.01e-3)" "unprognostic (2.23e-1)" "unprognostic (8.07e-2)" "unprognostic (2.62e-1)" "unprognostic (2.79e-2)" "unprognostic (2.72e-2)" "unprognostic (8.59e-2)" "unprognostic (3.92e-2)" "unprognostic (2.58e-1)" "unprognostic (8.96e-2)" "unprognostic (7.71e-3)" "unprognostic (2.90e-1)" "unprognostic (2.84e-1)" "unprognostic (2.08e-2)" PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Astrocytes: 1.4;Choroid plexus epithelial cells: 2.4" "Group enriched" "Detected in some" 4 "Ciliated cells: 2.4;Glial cells: 1.4" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5690 "Microglia and Neuropil: 569028.2" "Group enriched" "Detected in some" "intestine: 580127.2;skin: 1334881.8" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 1 "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.05e-2)" "unprognostic (7.07e-2)" "unprognostic (1.91e-1)" "unprognostic (2.68e-1)" "unprognostic (5.29e-3)" "unprognostic (2.56e-3)" "unprognostic (6.06e-3)" "unprognostic (1.49e-2)" "unprognostic (7.97e-2)" "unprognostic (3.46e-2)" "unprognostic (1.64e-1)" "unprognostic (1.29e-2)" PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.2" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Bergmann glia: 1.5;Choroid plexus epithelial cells: 1.3;Oligodendrocyte progenitor cells: 2.8" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.3;Glial cells: 2.8" "Low cell type specificity" "Detected in some" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 5.6;Skin Cutaneous Melanoma (TCGA): 16.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cancer enhanced" "Detected in some" "Sarcoma: 5.8;skin cancer: 5.7" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 24000 "Cluster 73: Brain - Neuronal signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.48e-2)" "unprognostic (1.99e-1)" "unprognostic (5.78e-2)" "unprognostic (1.54e-1)" "unprognostic (4.91e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (1.35e-1)" "unprognostic (6.62e-3)" "unprognostic (6.62e-2)" "unprognostic (2.17e-2)" "unprognostic (1.42e-1)" "unprognostic (1.19e-3)" "unprognostic (2.98e-1)" "unprognostic (2.64e-2)" "unprognostic (3.27e-3)" "unprognostic (7.40e-2)" "unprognostic (1.96e-2)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.9;Bergmann glia: 1.5;Brain inhibitory neurons: 1.2;Choroid plexus epithelial cells: 1.2;Ependymal cells: 1.4;Oligodendrocyte progenitor cells: 1.6" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.4;Glial cells: 1.9;Neuronal cells: 1.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Fibroblasts, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 750 "Pancreatic islets: 75034.5" "Tissue enriched" "Detected in single" 56 "cerebral cortex: 5628.7" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: , HPA010580: , HPA038625: " "unprognostic (1.24e-2)" "unprognostic (4.10e-1)" "unprognostic (1.31e-1)" "unprognostic (1.52e-2)" "unprognostic (7.82e-2)" "potential prognostic favorable (2.66e-6)" "unprognostic (5.18e-3)" "unprognostic (7.04e-3)" "unprognostic (9.83e-3)" "unprognostic (3.27e-1)" "unprognostic (8.18e-2)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (8.66e-2)" "unprognostic (9.27e-3)" "unprognostic (7.41e-2)" "unprognostic (4.30e-2)" PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Bergmann glia: 2.4;Ependymal cells: 2.2" "Cell type enhanced" "Detected in some" "Ciliated cells: 2.2;Glial cells: 3.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 922584.8;Microglia and Neuropil: 268919.7" "Group enriched" "Detected in some" 6616 "cerebral cortex: 431522.1;intestine: 891704.6" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 1 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.53e-1)" "unprognostic (4.16e-2)" "unprognostic (6.79e-2)" "unprognostic (3.22e-2)" "unprognostic (1.87e-2)" "unprognostic (7.63e-2)" "unprognostic (2.83e-1)" PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (8.90e-3)" "unprognostic (1.98e-1)" "unprognostic (1.78e-1)" "unprognostic (7.60e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.32e-4)" "unprognostic (1.77e-1)" "unprognostic (2.41e-2)" "unprognostic (2.13e-1)" "unprognostic (3.20e-1)" "unprognostic (2.58e-2)" "unprognostic (8.79e-3)" "unprognostic (2.68e-1)" "unprognostic (1.50e-1)" "unprognostic (1.04e-1)" "unprognostic (8.85e-2)" PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364162-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.2;Bergmann glia: 6.4;Brain excitatory neurons: 3.1;Brain inhibitory neurons: 2.8;Choroid plexus epithelial cells: 2.7;Ependymal cells: 3.9;Oligodendrocyte progenitor cells: 5.2;Oligodendrocytes: 1.9;Other brain neurons: 1.7" "Group enriched" "Detected in some" 13 "Ciliated cells: 3.9;Glial cells: 8.2;Neuronal cells: 3.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Prostate Adenocarcinoma (TCGA): 5.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Fibroblasts_1, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (2.01e-2)" "unprognostic (2.54e-2)" "unprognostic (2.83e-1)" "unprognostic (2.22e-2)" "unprognostic (1.37e-1)" "unprognostic (4.14e-3)" "unprognostic (4.60e-1)" "unprognostic (5.37e-2)" "unprognostic (5.97e-3)" "unprognostic (1.75e-2)" "unprognostic (4.94e-2)" "unprognostic (7.31e-3)" PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.6;Bergmann glia: 10.6;Brain excitatory neurons: 3.9;Brain inhibitory neurons: 3.5;Choroid plexus epithelial cells: 6.3;Ependymal cells: 7.2;Oligodendrocyte progenitor cells: 6.5;Oligodendrocytes: 3.7;Other brain neurons: 2.1" "Group enriched" "Detected in some" 15 "Ciliated cells: 7.2;Glial cells: 10.6;Neuronal cells: 3.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4539 "Fallopian tube cells: 453939.1" "Tissue enriched" "Detected in single" 192 "pancreas: 19198.7" "HPA008755, HPA010580" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: , HPA010580: " "unprognostic (7.48e-3)" "unprognostic (4.04e-2)" "unprognostic (2.46e-1)" "unprognostic (1.18e-1)" "unprognostic (1.48e-1)" "unprognostic (4.58e-2)" "unprognostic (4.21e-2)" "unprognostic (1.47e-1)" "unprognostic (4.37e-3)" "unprognostic (9.00e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-1)" "unprognostic (1.72e-2)" "unprognostic (1.48e-2)" "unprognostic (6.05e-2)" "unprognostic (1.14e-2)" "unprognostic (9.03e-3)" "unprognostic (1.08e-1)" "unprognostic (7.44e-2)" "unprognostic (2.42e-1)" "unprognostic (6.26e-2)" "unprognostic (1.97e-1)" PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 3.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.8;Bergmann glia: 1.8;Choroid plexus epithelial cells: 1.3;Ependymal cells: 2.2;Oligodendrocyte progenitor cells: 1.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 2.2;Glial cells: 1.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblasts_1, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (8.03e-2)" "unprognostic (1.17e-1)" "unprognostic (3.13e-1)" "unprognostic (2.19e-2)" "unprognostic (1.30e-2)" "unprognostic (2.71e-1)" "unprognostic (1.60e-2)" "unprognostic (4.11e-2)" "unprognostic (2.51e-2)" "unprognostic (2.33e-1)" "unprognostic (1.62e-1)" "unprognostic (2.10e-2)" "unprognostic (5.17e-2)" PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (4.02e-1)" "unprognostic (7.29e-2)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (2.96e-2)" "unprognostic (2.03e-2)" "unprognostic (2.97e-1)" PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402778-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.7;Bergmann glia: 1.4;Choroid plexus epithelial cells: 2.1;Ependymal cells: 1.3;Oligodendrocyte progenitor cells: 1.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 2.1;Glial cells: 1.9" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 10.3;Kidney Renal Clear Cell Carcinoma (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 9312 "cerebral cortex: 931210.4" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 22: Non-specific - Basic cellular functions" 1 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (3.92e-2)" "unprognostic (1.74e-1)" "unprognostic (7.50e-2)" "unprognostic (3.96e-2)" "unprognostic (3.53e-1)" "potential prognostic favorable (7.32e-6)" "unprognostic (8.15e-2)" "unprognostic (1.12e-1)" "unprognostic (4.36e-3)" "unprognostic (9.14e-3)" "unprognostic (6.29e-2)" "unprognostic (1.97e-1)" "unprognostic (5.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.77e-2)" "unprognostic (1.05e-1)" "unprognostic (3.21e-2)" "unprognostic (2.62e-1)" "unprognostic (4.32e-2)" "unprognostic (1.97e-1)" PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350099-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 1473 "cerebral cortex: 147327.0" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 73: Brain - Neuronal signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: , HPA010580: , HPA076182: " "potential prognostic unfavorable (3.30e-4)" "unprognostic (1.12e-2)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "unprognostic (1.30e-1)" "unprognostic (1.75e-1)" "unprognostic (1.30e-2)" "unprognostic (2.85e-3)" "unprognostic (1.00e-1)" "unprognostic (2.52e-2)" "unprognostic (4.56e-3)" "unprognostic (1.29e-2)" "unprognostic (1.77e-2)" "unprognostic (3.59e-2)" "unprognostic (2.64e-2)" "unprognostic (1.73e-2)" "unprognostic (2.09e-1)" "unprognostic (3.83e-2)" "unprognostic (4.19e-2)" "unprognostic (6.94e-2)" "unprognostic (2.46e-1)" "unprognostic (2.60e-1)" "unprognostic (1.25e-1)" "unprognostic (6.38e-2)" PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141359994-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.1;Oligodendrocyte progenitor cells: 1.4" "Cell type enhanced" "Detected in single" "Glial cells: 1.4" "Cell type enhanced" "Detected in some" "oligodendrocyte precursor cell: 2.1" "Cancer enriched" "Detected in many" 6 "Glioblastoma Multiforme (TCGA): 22.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: , HPA010580: , HPA077526: " "unprognostic (1.09e-2)" "unprognostic (2.12e-1)" "unprognostic (2.27e-1)" "unprognostic (1.61e-2)" "unprognostic (4.34e-3)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (3.08e-3)" "unprognostic (5.09e-1)" "unprognostic (3.69e-2)" "unprognostic (1.62e-2)" "unprognostic (7.89e-2)" "unprognostic (3.56e-1)" "unprognostic (2.08e-1)" "unprognostic (1.61e-1)" "unprognostic (1.10e-1)" "unprognostic (7.15e-2)" "unprognostic (8.02e-3)" "unprognostic (3.06e-3)" "unprognostic (3.07e-2)" "unprognostic (2.57e-1)" "unprognostic (1.91e-1)" "unprognostic (2.33e-2)" "unprognostic (6.13e-2)" PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in single" "Astrocytes: 1.1" "Cell type enhanced" "Detected in single" "Glial cells: 1.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.9" "Cancer enhanced" "Detected in single" "Glioblastoma Multiforme (TCGA): 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Cell type enriched" "Detected in single" 382 "Microglia and Neuropil: 38161.8" "Not detected" "Not detected" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: , HPA010580: , HPA035822: , HPA035823: " "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (9.39e-2)" "unprognostic (9.12e-2)" "unprognostic (5.20e-3)" "unprognostic (3.95e-2)" "unprognostic (3.78e-2)" PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.0;Bergmann glia: 9.2;Brain excitatory neurons: 4.0;Brain inhibitory neurons: 3.6;Choroid plexus epithelial cells: 6.3;Ependymal cells: 6.2;Oligodendrocyte progenitor cells: 7.5;Oligodendrocytes: 3.1;Other brain neurons: 2.2" "Group enriched" "Detected in some" 14 "Ciliated cells: 6.3;Glial cells: 9.2;Neuronal cells: 4.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 9.7;testis cancer: 14.2" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 28: Liver & Adrenal gland - Secretion" "Cluster 25: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA008755: , HPA010580: " "unprognostic (3.70e-1)" "unprognostic (2.68e-1)" "unprognostic (2.74e-1)" "unprognostic (7.46e-2)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "potential prognostic favorable (9.34e-5)" "unprognostic (8.90e-2)" "unprognostic (9.95e-3)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (9.78e-2)" "unprognostic (1.65e-1)" "unprognostic (1.16e-1)" "unprognostic (4.01e-2)" "unprognostic (6.04e-2)" "unprognostic (1.43e-1)" "unprognostic (4.78e-2)" "unprognostic (3.04e-1)" "unprognostic (4.13e-2)" PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397947-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 18.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 1.1;Choroid plexus epithelial cells: 1.7" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.7;Glial cells: 1.1" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2305 "Collecting ducts: 148045.5;Glomeruli: 312956.8" "Not detected" "Not detected" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 44: Non-specific - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" 3 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.25e-1)" "unprognostic (2.27e-2)" "unprognostic (4.43e-2)" "unprognostic (3.92e-2)" "unprognostic (3.03e-1)" "unprognostic (3.52e-1)" "unprognostic (3.49e-1)" "unprognostic (4.25e-1)" "validated prognostic favorable (2.38e-4)" "validated prognostic favorable (3.13e-4)" "unprognostic (2.13e-1)" "unprognostic (9.67e-2)" "unprognostic (4.61e-3)" "unprognostic (3.17e-1)" "unprognostic (2.28e-1)" "unprognostic (1.06e-3)" "unprognostic (2.58e-1)" "unprognostic (2.47e-2)" "unprognostic (3.22e-1)" "unprognostic (3.24e-1)" "unprognostic (3.70e-2)" "unprognostic (1.31e-1)" "unprognostic (3.43e-2)" "unprognostic (1.34e-2)" "unprognostic (3.33e-1)" "unprognostic (2.07e-1)" "unprognostic (1.78e-1)" PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.7" "Cell type enhanced" "Detected in some" "Astrocytes: 6.1;Bergmann glia: 6.6;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 2.5;Choroid plexus epithelial cells: 5.2;Ependymal cells: 3.5;Microglia: 1.1;Oligodendrocyte progenitor cells: 4.4;Oligodendrocytes: 2.1;Other brain neurons: 2.1" "Group enriched" "Detected in some" 8 "Ciliated cells: 5.2;Glial cells: 6.6;Neuronal cells: 2.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 7.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.58e-1)" "unprognostic (1.03e-1)" "unprognostic (3.67e-1)" "unprognostic (2.19e-1)" "unprognostic (1.93e-1)" "unprognostic (2.16e-1)" "unprognostic (4.04e-1)" "unprognostic (3.62e-1)" "unprognostic (3.18e-1)" "unprognostic (2.52e-3)" "unprognostic (1.39e-3)" "unprognostic (2.09e-1)" "unprognostic (1.66e-2)" "unprognostic (1.42e-1)" "unprognostic (1.96e-1)" "unprognostic (3.73e-2)" "unprognostic (1.66e-2)" "unprognostic (1.60e-1)" "unprognostic (2.25e-1)" "unprognostic (9.81e-2)" "unprognostic (1.64e-1)" "unprognostic (7.51e-2)" "unprognostic (1.31e-1)" "unprognostic (2.43e-2)" "unprognostic (3.55e-1)" "unprognostic (2.11e-2)" "unprognostic (3.86e-2)" PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Bergmann glia: 2.5;Brain excitatory neurons: 1.1;Choroid plexus epithelial cells: 1.9;Ependymal cells: 1.6;Oligodendrocyte progenitor cells: 1.9" "Group enriched" "Detected in some" 5 "Ciliated cells: 1.9;Glial cells: 2.5;Neuronal cells: 1.1" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 23.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 14.2;Rhabdoid: 16.1" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 28013 "Glomeruli: 2801313.9" "Tissue enriched" "Detected in single" 6232 "intestine: 623249.0" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 4400 "Cluster 73: Brain - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 5: Rhabdoid - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (4.29e-1)" "unprognostic (8.58e-2)" "unprognostic (7.91e-2)" "unprognostic (8.46e-3)" "unprognostic (8.47e-2)" "unprognostic (2.07e-1)" "unprognostic (1.68e-1)" "unprognostic (2.74e-1)" "unprognostic (1.62e-1)" "unprognostic (4.92e-3)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.14e-2)" "unprognostic (8.49e-2)" "unprognostic (3.08e-1)" "unprognostic (8.18e-3)" "unprognostic (6.96e-2)" "unprognostic (4.73e-2)" "unprognostic (5.48e-2)" "unprognostic (2.88e-2)" "unprognostic (1.85e-2)" "unprognostic (3.06e-2)" "unprognostic (2.90e-2)" "unprognostic (4.24e-3)" "unprognostic (5.42e-3)" "unprognostic (1.86e-2)" "unprognostic (4.62e-1)" "unprognostic (1.68e-1)" "unprognostic (3.24e-2)" PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512975 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 17.3;retina: 6.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 16.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 3.1;testis cancer: 9.0" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7520 "Microglia and Neuropil: 585880.6;Neurons: 918072.6" "Tissue enriched" "Detected in single" 27 "cerebral cortex: 2657.3" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: " "unprognostic (1.76e-2)" "unprognostic (1.08e-1)" "unprognostic (1.01e-1)" "unprognostic (3.49e-2)" "unprognostic (1.83e-2)" "unprognostic (6.72e-2)" PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 "Protocadherin gamma subfamily C, 5" Q9Y5F6 5 141489081-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 28.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 4.4;testis cancer: 6.8" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10526 "Astrocytes and Neuropil: 1215263.6;Microglia and Neuropil: 1118983.5;Neurons: 823486.4" "Tissue enriched" "Detected in single" 39305 "cerebral cortex: 3930540.5" "HPA008755, HPA010580, HPA076140" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: , HPA010580: , HPA076140: " "unprognostic (9.29e-3)" "unprognostic (1.35e-1)" "unprognostic (1.14e-1)" "unprognostic (1.27e-1)" "unprognostic (6.36e-3)" "unprognostic (3.31e-3)" PCIF1 "bA465L10.1, C20orf67, CAPAM, PPP1R121" ENSG00000100982 "Phosphorylated CTD interacting factor 1" Q9H4Z3 20 45934683-45948023 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 5351739.7" "Tissue enhanced" "Detected in many" "bone marrow: 13105374.6" HPA049517 Enhanced Supported "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 41: Basophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "Microtubules, Cytokinetic bridge" "HPA049517: " "potential prognostic favorable (1.69e-4)" "unprognostic (4.68e-2)" "unprognostic (2.36e-1)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (2.07e-1)" "unprognostic (8.06e-2)" "unprognostic (5.80e-2)" "unprognostic (2.23e-2)" "unprognostic (1.83e-1)" "unprognostic (8.14e-3)" "unprognostic (5.11e-2)" "unprognostic (4.48e-3)" "unprognostic (4.33e-3)" "unprognostic (6.22e-3)" "unprognostic (1.11e-1)" "unprognostic (4.22e-3)" "unprognostic (4.69e-1)" "unprognostic (1.74e-1)" "unprognostic (1.62e-1)" "unprognostic (4.84e-2)" "unprognostic (1.35e-2)" "unprognostic (3.98e-3)" "unprognostic (3.95e-1)" "unprognostic (1.91e-1)" "unprognostic (1.78e-3)" "unprognostic (3.85e-2)" "unprognostic (7.21e-2)" "unprognostic (1.14e-1)" "unprognostic (1.36e-1)" "unprognostic (4.68e-2)" PCMT1 ENSG00000120265 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase" P22061 6 149749444-149811420 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 1214.2;Late primary spermatocytes: 414.6;Late spermatids: 616.2;Neutrophil progenitors: 536.6" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1214.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA003239 Approved Supported Cytosol No No 2200000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 23 Cytosol "HPA003239: " "unprognostic (3.87e-2)" "validated prognostic unfavorable (5.19e-7)" "validated prognostic unfavorable (5.23e-4)" "unprognostic (1.25e-2)" "unprognostic (1.17e-2)" "unprognostic (1.82e-3)" "unprognostic (1.30e-1)" "unprognostic (9.92e-2)" "potential prognostic unfavorable (2.96e-5)" "unprognostic (2.60e-2)" "potential prognostic favorable (2.67e-6)" "unprognostic (4.64e-2)" "unprognostic (1.88e-1)" "validated prognostic unfavorable (6.85e-6)" "validated prognostic unfavorable (9.76e-4)" "unprognostic (3.22e-2)" "unprognostic (1.12e-1)" "unprognostic (5.01e-3)" "unprognostic (2.49e-1)" "unprognostic (2.02e-2)" "unprognostic (8.26e-3)" "unprognostic (1.69e-1)" "unprognostic (1.14e-2)" "unprognostic (1.57e-1)" "unprognostic (2.67e-2)" "unprognostic (6.42e-2)" "unprognostic (8.57e-2)" "unprognostic (2.45e-1)" "unprognostic (2.68e-1)" "unprognostic (3.82e-2)" "unprognostic (2.38e-1)" PCMTD2 "C20orf36, FLJ10883" ENSG00000203880 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2" Q9NV79 20 64255695-64304820 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 164.6" "Cell type enhanced" "Detected in many" "Oligodendrocyte progenitor cells: 167.9;Podocytes: 186.3;Retinal pigment epithelial cells: 127.9" "Cell type enhanced" "Detected in many" "Glial cells: 167.9;Renal nephron cells: 186.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 893514.8" "Tissue enriched" "Detected in single" 15156 "intestine: 1515599.7" HPA057849 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 11: T-cells - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 16: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 57: Podocytes - Glomerular filtration" 12 Mitochondria Nucleoplasm "HPA057849: " "unprognostic (3.71e-3)" "unprognostic (1.43e-1)" "unprognostic (7.79e-2)" "unprognostic (6.70e-2)" "unprognostic (1.18e-1)" "unprognostic (2.35e-1)" "unprognostic (5.16e-1)" "unprognostic (3.27e-2)" "unprognostic (4.84e-2)" "unprognostic (3.53e-2)" "potential prognostic favorable (4.21e-6)" "unprognostic (1.84e-3)" "unprognostic (2.53e-1)" "unprognostic (9.67e-2)" "unprognostic (8.93e-2)" "unprognostic (1.34e-2)" "unprognostic (6.23e-2)" "unprognostic (4.42e-2)" "unprognostic (7.75e-2)" "unprognostic (2.82e-2)" "unprognostic (5.89e-2)" "unprognostic (2.53e-2)" "unprognostic (6.56e-2)" "unprognostic (2.68e-2)" "unprognostic (5.79e-2)" "unprognostic (1.90e-2)" "unprognostic (3.32e-1)" "unprognostic (2.43e-1)" "unprognostic (3.45e-2)" "unprognostic (2.04e-2)" "unprognostic (2.09e-1)" PCNA ENSG00000132646 "Proliferating cell nuclear antigen" P12004 20 5114953-5126626 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Host-virus interaction" DNA-binding "Cancer-related genes, Deafness, Disease variant, Dwarfism, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 361.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 191.3;Early spermatids: 233.2;Erythrocyte progenitors: 361.4;Esophageal basal cells: 217.0;Late primary spermatocytes: 240.5;Migrating cytotrophoblasts: 238.2;Monocyte progenitors: 236.8;Oocytes: 492.7" "Cell type enhanced" "Detected in all" "Erythrocytes: 361.4;Oocytes: 492.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Pancreas - Macrophages, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 29533427.3" "Tissue enhanced" "Detected in all" "bone marrow: 104777323.4" "CAB000148, HPA030521, HPA030522, HPA030523, CAB080239, CAB080240, CAB080241, CAB080242" Enhanced Enhanced Nucleoplasm No Yes 130000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 245 Nucleoplasm "CAB000148: , CAB080239: , CAB080240: , CAB080241: , CAB080242: , HPA030521: , HPA030522: , HPA030523: " "unprognostic (2.49e-1)" "unprognostic (6.13e-2)" "unprognostic (2.63e-2)" "potential prognostic favorable (3.89e-4)" "unprognostic (4.37e-2)" "unprognostic (1.58e-1)" "unprognostic (2.30e-1)" "unprognostic (2.97e-1)" "unprognostic (5.89e-3)" "potential prognostic unfavorable (1.50e-4)" "potential prognostic favorable (4.61e-4)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (7.46e-4)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (4.24e-6)" "potential prognostic unfavorable (7.43e-4)" "unprognostic (7.72e-3)" "unprognostic (2.53e-2)" "unprognostic (2.43e-1)" "unprognostic (1.77e-1)" "unprognostic (9.45e-2)" "unprognostic (6.29e-3)" "unprognostic (4.44e-1)" "unprognostic (7.32e-2)" "unprognostic (2.76e-2)" "unprognostic (6.53e-3)" "unprognostic (1.18e-1)" "unprognostic (1.34e-2)" "unprognostic (9.25e-2)" "unprognostic (3.70e-3)" "unprognostic (1.50e-1)" PCNP ENSG00000081154 "PEST proteolytic signal containing nuclear protein" Q8WW12 3 101574180-101594465 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "T-cells: 6039932.8" "Low tissue specificity" "Detected in all" "HPA035011, HPA063861" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No 36000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 103: Non-specific - Basic cellular processes" 16 Nucleoplasm "Nuclear bodies" "HPA035011: , HPA063861: " "unprognostic (2.74e-1)" "unprognostic (1.47e-2)" "unprognostic (1.54e-2)" "unprognostic (1.41e-1)" "unprognostic (7.56e-2)" "unprognostic (1.32e-1)" "unprognostic (3.67e-1)" "potential prognostic unfavorable (4.17e-4)" "unprognostic (1.39e-1)" "unprognostic (1.70e-3)" "potential prognostic favorable (1.78e-5)" "unprognostic (1.69e-1)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (6.49e-6)" "unprognostic (1.30e-2)" "unprognostic (1.72e-1)" "unprognostic (4.06e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-1)" "unprognostic (2.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.87e-2)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (5.07e-2)" "unprognostic (3.04e-2)" "unprognostic (2.90e-2)" "unprognostic (2.77e-2)" "unprognostic (5.98e-2)" "unprognostic (8.97e-2)" "unprognostic (8.56e-2)" "unprognostic (1.89e-1)" PCNT "KEN, KIAA0402, PCN, PCNT2, PCNTB, SCKL4" ENSG00000160299 Pericentrin O95613 21 46324124-46445769 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "skeletal muscle: 234.7" "Group enriched" "Detected in many" 5 "Myonuclei: 757.7;Thymic myoid cells: 1000.7" "Group enriched" "Detected in all" 6 "Myocytes: 757.7;Stromal cells: 1000.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" "intestine: 2760044.1;Stomach: 7375550.4" "HPA016820, HPA019887, HPA032101" Approved Supported "Centriolar satellite,Centrosome,Cytosol,Flagellar centriole,Mid piece" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 27 Centrosome "Centriolar satellite, Cytosol, Flagellar centriole, Mid piece" "HPA016820: , HPA019887: , HPA032101: " "unprognostic (2.12e-1)" "unprognostic (4.08e-2)" "unprognostic (1.85e-2)" "unprognostic (2.06e-1)" "unprognostic (6.96e-2)" "unprognostic (2.76e-1)" "unprognostic (3.62e-1)" "unprognostic (8.48e-2)" "unprognostic (2.82e-2)" "unprognostic (7.85e-2)" "unprognostic (2.64e-1)" "unprognostic (2.90e-1)" "unprognostic (1.77e-2)" "unprognostic (3.65e-3)" "unprognostic (1.35e-2)" "unprognostic (5.55e-2)" "unprognostic (9.79e-2)" "unprognostic (1.02e-1)" "unprognostic (1.65e-3)" "unprognostic (9.59e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (2.46e-4)" "unprognostic (6.61e-3)" "unprognostic (5.71e-2)" "unprognostic (1.76e-2)" "unprognostic (1.13e-1)" "unprognostic (2.78e-1)" "unprognostic (2.36e-1)" "unprognostic (2.10e-2)" "unprognostic (1.20e-1)" "unprognostic (3.98e-1)" PCOLCE "PCPE, PCPE1" ENSG00000106333 "Procollagen C-endopeptidase enhancer" Q15113 7 100602363-100608175 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Decidual stromal cells: 2746.3" "Cell type enriched" "Detected in many" 5 "Stromal cells: 2746.3" "Cell type enriched" "Detected in many" 6 "fibroblast: 156.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 209.7;Neuroblastoma: 253.8;Sarcoma: 172.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Lung - Fibroblasts_2, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 106.9" "Cell type enriched" "Detected in many" "Smooth muscle cells: 29139245.4" "Group enriched" "Detected in all" "blood vessel: 133429735.3;skin: 58240171.6" "CAB017623, HPA042927" Approved Approved "Golgi apparatus,Vesicles" "Secreted to extracellular matrix" "No annotated function" NA NA 320000000 "Cluster 35: Non-specific - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "Golgi apparatus, Vesicles" "CAB017623: , HPA042927: " "unprognostic (9.81e-2)" "unprognostic (2.84e-1)" "unprognostic (3.73e-2)" "unprognostic (7.30e-3)" "unprognostic (6.11e-2)" "unprognostic (1.70e-1)" "unprognostic (2.27e-2)" "unprognostic (3.20e-3)" "unprognostic (6.11e-2)" "unprognostic (8.26e-2)" "unprognostic (9.13e-3)" "unprognostic (5.39e-3)" "potential prognostic unfavorable (3.07e-4)" "unprognostic (1.11e-2)" "unprognostic (5.78e-3)" "unprognostic (9.46e-2)" "unprognostic (8.35e-2)" "unprognostic (4.03e-2)" "unprognostic (2.89e-1)" "unprognostic (1.04e-3)" "unprognostic (1.85e-1)" "unprognostic (1.61e-1)" "unprognostic (1.82e-1)" "unprognostic (5.15e-2)" "unprognostic (6.03e-2)" "unprognostic (3.69e-3)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (3.38e-2)" "unprognostic (6.56e-2)" "unprognostic (2.58e-2)" "unprognostic (8.79e-2)" PCP2 "GPSM4, MGC41903" ENSG00000174788 "Purkinje cell protein 2" Q8IVA1 19 7631611-7633719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 111.4;retina: 31.1;testis: 110.8" "Cell type enriched" "Detected in many" 6 "Late spermatids: 6837.6" "Cell type enriched" "Detected in many" 17 "Spermatogenic cell types: 6837.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 4.1;leukocyte: 1.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 5 "cerebellum: 115.1;white matter: 36.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Leukemia: 4.9" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Testis - Late spermatids" "Region enriched" "Detected in many" 44 "cerebellum: 2160.1" "Region enriched" "Detected in all" 25 "cerebellum: 324.4" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "heart muscle: 375948.2" HPA057428 Approved "Nuclear speckles,Vesicles" Yes NA "Cluster 35: Neutrophils - Protein binding" "Cluster 67: Testis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 4 "Nuclear speckles" Vesicles "HPA057428: " "unprognostic (9.73e-2)" "unprognostic (2.71e-3)" "unprognostic (7.86e-2)" "potential prognostic favorable (3.27e-4)" "unprognostic (2.56e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (1.96e-4)" "unprognostic (4.57e-2)" "unprognostic (2.86e-1)" "unprognostic (4.89e-2)" "unprognostic (1.98e-2)" "unprognostic (1.05e-1)" "unprognostic (6.60e-3)" "unprognostic (1.53e-1)" "unprognostic (2.05e-1)" "unprognostic (1.64e-2)" "unprognostic (1.17e-1)" "unprognostic (3.01e-1)" "unprognostic (8.32e-3)" "unprognostic (1.55e-1)" "unprognostic (1.98e-1)" "unprognostic (2.76e-1)" "unprognostic (7.94e-3)" "unprognostic (3.47e-1)" "unprognostic (5.00e-1)" "unprognostic (1.52e-1)" PCYT1A "CCTalpha, CT, CTPCT, PCYT1" ENSG00000161217 "Phosphate cytidylyltransferase 1A, choline" P49585 3 196214222-196287957 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Nucleotidyltransferase, Transferase" "Cone-rod dystrophy, Congenital generalized lipodystrophy, Diabetes mellitus, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 196.6" "Cell type enhanced" "Detected in all" "Neutrophils: 196.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA035428 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 63: Non-specific - Protein processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 19 Nucleoplasm Cytosol "HPA035428: " "unprognostic (3.94e-1)" "unprognostic (8.24e-3)" "unprognostic (3.64e-2)" "unprognostic (7.15e-2)" "unprognostic (1.99e-1)" "unprognostic (3.00e-2)" "unprognostic (7.67e-2)" "unprognostic (5.83e-2)" "unprognostic (1.98e-1)" "unprognostic (1.25e-2)" "unprognostic (5.91e-3)" "unprognostic (2.29e-1)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (2.62e-1)" "unprognostic (2.49e-2)" "unprognostic (1.53e-3)" "unprognostic (8.36e-2)" "unprognostic (5.28e-2)" "unprognostic (1.11e-2)" "unprognostic (8.06e-2)" "unprognostic (4.68e-2)" "unprognostic (6.37e-3)" "unprognostic (3.60e-2)" "unprognostic (1.66e-2)" "unprognostic (7.53e-2)" "unprognostic (1.24e-3)" "unprognostic (1.86e-1)" "unprognostic (2.31e-1)" "unprognostic (6.50e-3)" "unprognostic (3.07e-1)" PDCD2 "RP8, ZMYND7" ENSG00000071994 "Programmed cell death 2" Q16342 6 170575295-170584692 "Essential proteins, Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 212497.3" "Tissue enriched" "Detected in many" "lymphoid tissue: 285546.0" "HPA026713, HPA075534" Approved Approved "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 21 Nucleoplasm "Cytokinetic bridge" "HPA026713: , HPA075534: " "unprognostic (4.14e-3)" "potential prognostic unfavorable (4.07e-5)" "unprognostic (1.45e-1)" "unprognostic (1.34e-2)" "unprognostic (1.33e-1)" "unprognostic (1.37e-2)" "unprognostic (1.04e-1)" "unprognostic (1.19e-2)" "unprognostic (3.94e-2)" "potential prognostic unfavorable (9.09e-4)" "potential prognostic favorable (1.80e-4)" "unprognostic (1.20e-1)" "unprognostic (3.82e-2)" "validated prognostic unfavorable (2.08e-9)" "validated prognostic unfavorable (1.49e-5)" "unprognostic (2.04e-2)" "unprognostic (1.44e-1)" "unprognostic (7.13e-2)" "unprognostic (3.80e-2)" "unprognostic (2.83e-3)" "unprognostic (5.33e-2)" "unprognostic (4.84e-1)" "unprognostic (6.06e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-2)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.42e-1)" "unprognostic (2.37e-1)" "unprognostic (1.86e-1)" "unprognostic (2.36e-1)" PDCD6 "ALG-2, PEF1B" ENSG00000249915 "Programmed cell death 6" O75340 5 271621-314974 "Plasma proteins, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 36.4;Bergmann glia: 41.5;Brain excitatory neurons: 57.0;Brain inhibitory neurons: 47.2;Choroid plexus epithelial cells: 57.1;Distal convoluted tubule cells: 50.7;Ependymal cells: 44.7;Loop of henle epithelial cells: 46.5;Microglia: 53.4;Oligodendrocyte progenitor cells: 36.8;Oligodendrocytes: 60.8;Other brain neurons: 57.6;Papillary tip epithelial cells: 28.8;Podocytes: 56.3;Proximal tubule cells: 45.6;Renal collecting duct intercalated cells: 51.9;Renal collecting duct principal cells: 39.3;Renal connecting tubule cells: 48.2" "Cell type enhanced" "Detected in some" "Ciliated cells: 57.1;Ductal cells: 51.9;Glial cells: 60.8;Neuronal cells: 57.6;Renal nephron cells: 56.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA047221 Supported Nucleoplasm,Cytosol No No 1400000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 50 Cytosol Nucleoplasm "HPA047221: " "unprognostic (9.50e-2)" "unprognostic (4.47e-3)" "unprognostic (5.22e-3)" "unprognostic (3.25e-1)" "unprognostic (1.16e-1)" "unprognostic (9.17e-2)" "unprognostic (4.05e-3)" "unprognostic (1.34e-2)" "unprognostic (1.61e-1)" "unprognostic (4.94e-3)" "unprognostic (7.50e-3)" "unprognostic (2.56e-2)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (5.78e-6)" "unprognostic (2.15e-3)" "unprognostic (6.29e-2)" "unprognostic (8.85e-2)" "unprognostic (3.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (2.71e-1)" "unprognostic (1.20e-1)" "unprognostic (5.24e-2)" "unprognostic (1.68e-1)" "unprognostic (8.18e-2)" "unprognostic (1.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.53e-1)" "unprognostic (1.27e-1)" "unprognostic (5.95e-2)" PDCL2 GCPHLP ENSG00000163440 "Phosducin like 2" Q8N4E4 4 55556519-55592245 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 206 "testis: 61.8" "Group enriched" "Detected in some" 17 "Early spermatids: 1630.0;Late primary spermatocytes: 529.8;Late spermatids: 904.2" "Cell type enriched" "Detected in some" 141 "Spermatogenic cell types: 1630.0" "Cell type enhanced" "Detected in some" "MGE interneuron: 8.6;thalamic excitatory: 5.4" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 2.5;Testicular Germ Cell Tumor (TCGA): 4.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" "Alveolar cell types: 543189.5;Cardiomyocytes: 141720.2" "Tissue enriched" "Detected in some" "intestine: 83562.5" "HPA048260, HPA072384" Enhanced Approved Microtubules,Centrosome NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 24: Non-specific - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Microtubules Centrosome "HPA048260: , HPA072384: " "unprognostic (1.89e-1)" "unprognostic (5.24e-3)" "unprognostic (3.77e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (7.93e-5)" PDCL3 VIAF1 ENSG00000115539 "Phosducin like 3" Q9H2J4 2 100562993-100576739 "Essential proteins, Predicted intracellular proteins" "Angiogenesis, Apoptosis" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 142.8;Undifferentiated spermatogonia: 84.7" "Cell type enhanced" "Detected in many" "Oocytes: 142.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 31974358.2" "Tissue enhanced" "Detected in many" "lymphoid tissue: 8232586.4" "HPA018469, HPA027094" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 9: T-cells - Adaptive immunity: Regulation" 81 Cytosol Nucleoplasm "HPA018469: , HPA027094: " "unprognostic (6.11e-2)" "unprognostic (2.26e-2)" "unprognostic (1.14e-1)" "unprognostic (2.48e-3)" "unprognostic (3.66e-3)" "unprognostic (2.06e-1)" "unprognostic (7.49e-2)" "potential prognostic unfavorable (7.40e-4)" "unprognostic (1.68e-2)" "unprognostic (4.12e-2)" "unprognostic (4.34e-2)" "unprognostic (2.39e-1)" "unprognostic (3.50e-2)" "validated prognostic unfavorable (1.92e-4)" "validated prognostic unfavorable (1.95e-5)" "unprognostic (8.84e-3)" "unprognostic (2.26e-2)" "unprognostic (5.65e-2)" "unprognostic (5.85e-2)" "unprognostic (1.32e-1)" "unprognostic (1.35e-1)" "unprognostic (2.18e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-1)" "unprognostic (1.70e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (2.35e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (1.29e-1)" PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 19.9;heart muscle: 28.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 4516.2;Enterocytes: 856.4;Pancreatic duct cells: 665.0;Pericytes: 705.6;Pituicytes/FSCs: 1070.1;Retinal amacrine cells: 730.9;Retinal bipolar cells: 581.8;Retinal horizontal cells: 1166.0;Vascular smooth muscle cells: 1060.7" "Cell type enhanced" "Detected in many" "Glial cells: 1070.1;Mural cells: 1060.7;Myocytes: 4516.2;Neuronal cells: 1166.0" "Cell type enriched" "Detected in all" 4 "vascular associated smooth muscle cell: 2523.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 7.4" "Adipose subcutaneous - Smooth muscle cells, Breast - Endothelial cells, Prostate - Smooth muscle cells, Skin - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.4" "Group enriched" "Detected in many" "Capillaries: 10118622.2;Cardiomyocytes: 28201489.6" "Tissue enhanced" "Detected in many" "heart muscle: 5665768.9" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 24000 "Cluster 35: Non-specific - Mixed function" "Cluster 38: Sub-cortical - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 "Plasma membrane" "HPA014492: , HPA074258: " "unprognostic (6.53e-2)" "unprognostic (8.36e-2)" "unprognostic (7.11e-3)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (2.67e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-3)" "potential prognostic favorable (4.05e-4)" "unprognostic (6.80e-2)" "unprognostic (3.94e-2)" "unprognostic (1.42e-2)" "unprognostic (2.96e-1)" "unprognostic (3.96e-1)" "unprognostic (2.73e-1)" "unprognostic (1.31e-1)" "unprognostic (2.90e-2)" "unprognostic (3.03e-1)" "unprognostic (5.24e-2)" "unprognostic (1.48e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (1.64e-1)" "unprognostic (1.03e-1)" PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469630 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 306.8;Innate lymphoid cells: 297.4;Late spermatids: 399.1;Macrophages: 130.5;Mast cells: 256.9;monocytes: 205.8;NK-cells: 237.4;pDCs: 153.3;T-cells: 187.5" "Cell type enhanced" "Detected in many" "dendritic cells: 306.8;Innate lymphoid cells: 297.4;Mast cells: 256.9;NK-cells: 237.4;Spermatogenic cell types: 399.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 128515.8;Microglia and Neuropil: 510586.5" "Tissue enriched" "Detected in some" "salivary gland: 4753963.4" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Plasma membrane" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Plasma membrane" "CAB017632: , HPA043310: , HPA076091: " "unprognostic (6.10e-3)" "unprognostic (1.21e-3)" "unprognostic (5.89e-2)" "unprognostic (1.37e-1)" "unprognostic (6.44e-2)" "unprognostic (1.88e-2)" "unprognostic (5.99e-2)" "unprognostic (5.61e-2)" "unprognostic (5.69e-2)" "unprognostic (8.71e-2)" "unprognostic (1.96e-3)" "unprognostic (2.05e-2)" "unprognostic (1.94e-1)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (2.72e-1)" "unprognostic (1.93e-2)" "unprognostic (3.51e-2)" "unprognostic (8.93e-2)" "potential prognostic unfavorable (8.66e-4)" "unprognostic (3.94e-2)" "unprognostic (8.68e-3)" "unprognostic (2.10e-1)" "unprognostic (2.12e-1)" "unprognostic (3.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.35e-2)" "unprognostic (7.77e-2)" "unprognostic (2.47e-2)" "unprognostic (1.27e-1)" "unprognostic (2.38e-1)" PDE4B DPDE4 ENSG00000184588 "Phosphodiesterase 4B" Q07343 1 65792514-66374579 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 71.3" "Cell type enhanced" "Detected in many" "Astrocytes: 983.5;Bergmann glia: 1175.3;monocytes: 1059.4;Neutrophils: 3699.4;Oligodendrocyte progenitor cells: 2472.8;Oligodendrocytes: 4839.5;pDCs: 1134.6;Plasma cells: 892.7;Retinal bipolar cells: 1183.4;Retinal horizontal cells: 1765.0" "Cell type enhanced" "Detected in many" "Glial cells: 4839.5;Neuronal cells: 1765.0;Neutrophils: 3699.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 5976.5" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 64.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 89.5" "Group enriched" "Detected in all" 5 "B-cells: 37.6;granulocytes: 89.5;T-cells: 34.8" "Cancer enhanced" "Detected in many" "Rhabdoid: 47.5" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12207 "Astrocytes and Neuropil: 1493645.1;Microglia and Neuropil: 1108427.8;Neurons: 1059973.3" "Tissue enriched" "Detected in some" "cerebral cortex: 37236504.6" HPA003005 Uncertain Approved "Golgi apparatus,Primary cilium,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 8 "Golgi apparatus" "Primary cilium, Cytosol" "HPA003005: " "unprognostic (2.02e-1)" "unprognostic (1.57e-1)" "unprognostic (1.94e-2)" "unprognostic (1.53e-1)" "unprognostic (4.87e-2)" "unprognostic (7.90e-2)" "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (8.85e-3)" "unprognostic (5.31e-2)" "unprognostic (5.20e-2)" "unprognostic (6.07e-3)" "unprognostic (3.94e-1)" "unprognostic (1.40e-1)" "unprognostic (1.94e-1)" "potential prognostic favorable (5.48e-4)" "unprognostic (5.17e-2)" "unprognostic (1.68e-1)" "unprognostic (1.29e-1)" "unprognostic (2.70e-3)" "unprognostic (5.40e-1)" "unprognostic (6.51e-2)" "unprognostic (3.07e-1)" "unprognostic (3.98e-2)" "unprognostic (5.31e-1)" "unprognostic (8.69e-2)" "unprognostic (1.81e-2)" "unprognostic (7.48e-3)" "unprognostic (2.47e-1)" "unprognostic (6.15e-3)" "unprognostic (3.10e-1)" PDE4C DPDE1 ENSG00000105650 "Phosphodiesterase 4C" Q08493 19 18207965-18248200 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 10.8;tongue: 23.0" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Bergmann glia: 1.2;Brain excitatory neurons: 6.1;Brain inhibitory neurons: 3.0;Ependymal cells: 1.3;Other brain neurons: 2.5;Pericytes: 4.4;Vascular smooth muscle cells: 4.9" "Group enriched" "Detected in some" 4 "Mural cells: 4.9;Neuronal cells: 6.1" "Group enriched" "Detected in many" 5 "pericyte: 107.6;vascular associated smooth muscle cell: 88.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 925 "Microglia and Neuropil: 92546.5" "Not detected" "Not detected" "HPA048975, HPA054218" Approved Approved "Midbody ring,Centrosome,Basal body,Cytosol" Yes NA "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 22: Non-specific - Basic cellular functions" "Centrosome, Basal body, Cytosol" "Midbody ring" "HPA048975: , HPA054218: " "unprognostic (7.28e-2)" "unprognostic (7.85e-2)" "unprognostic (2.52e-1)" "unprognostic (6.93e-3)" "unprognostic (5.55e-2)" "unprognostic (1.21e-3)" "unprognostic (5.57e-2)" "unprognostic (2.42e-2)" "unprognostic (7.16e-2)" "unprognostic (1.57e-1)" "unprognostic (1.36e-1)" "unprognostic (4.83e-2)" PDE6B "CSNB3, CSNBAD2, PDEB, rd1, RP40" ENSG00000133256 "Phosphodiesterase 6B" P35913 4 625573-670782 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Vision" Hydrolase "Congenital stationary night blindness, Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "retina: 357.2" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 628.1" "Cell type enriched" "Detected in many" 9 "Neuronal cells: 628.1" "Cell type enhanced" "Detected in many" "oligodendrocyte: 86.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054148, HPA059929" Enhanced Uncertain "Vesicles,Basal body,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 42: Retina - Visual perception" "Cluster 11: White matter - Signal transduction" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 79: Photoreceptor cells - Phototransduction" 1 "Basal body, Cytosol" Vesicles "HPA054148: , HPA059929: " "unprognostic (4.81e-3)" "unprognostic (1.06e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (1.32e-4)" "unprognostic (2.20e-1)" "unprognostic (1.53e-1)" "unprognostic (7.79e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (8.44e-3)" "unprognostic (3.25e-2)" "unprognostic (3.65e-3)" "unprognostic (1.12e-2)" "potential prognostic favorable (6.96e-4)" "potential prognostic unfavorable (3.03e-4)" "potential prognostic favorable (4.68e-4)" "unprognostic (3.75e-1)" "unprognostic (4.90e-2)" "unprognostic (1.61e-1)" "unprognostic (1.49e-1)" "unprognostic (1.10e-1)" "unprognostic (9.31e-3)" "unprognostic (1.83e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-1)" "unprognostic (2.87e-2)" "unprognostic (1.73e-1)" "unprognostic (6.53e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.46e-1)" PDE7B ENSG00000171408 "Phosphodiesterase 7B" Q9NP56 6 135851701-136195574 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 539.3;Distal convoluted tubule cells: 477.6;Mast cells: 457.9;Medullary thymic epithelial cells: 547.3;Myosatellite cells: 630.7;Oligodendrocyte progenitor cells: 510.8;Pituicytes/FSCs: 2708.0;Podocytes: 906.7;Renal collecting duct principal cells: 673.2" "Cell type enhanced" "Detected in many" "Glial cells: 2708.0;Renal nephron cells: 906.7" "Cell type enhanced" "Detected in all" "medium spiny neuron: 1106.8;pericyte: 2559.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 5.1" "Colon - Enteric glia cells" "Region enriched" "Detected in all" 5 "basal ganglia: 125.4" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1954 "Granulosa cells: 195421.0" "Not detected" "Not detected" HPA023967 Uncertain Approved Nucleoplasm No NA "Cluster 18: Non-specific - Translation" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" Nucleoplasm "HPA023967: " "unprognostic (2.22e-2)" "unprognostic (1.94e-1)" "unprognostic (5.47e-2)" "unprognostic (1.36e-1)" "unprognostic (3.71e-1)" "unprognostic (2.13e-3)" "unprognostic (3.49e-1)" "validated prognostic favorable (7.76e-7)" "validated prognostic favorable (1.67e-4)" "potential prognostic favorable (2.48e-4)" "potential prognostic favorable (1.20e-4)" "unprognostic (3.40e-1)" "unprognostic (6.59e-2)" "unprognostic (2.42e-1)" "unprognostic (9.09e-3)" "unprognostic (1.91e-2)" "unprognostic (2.72e-2)" "unprognostic (4.58e-2)" "unprognostic (8.64e-2)" "unprognostic (5.59e-3)" "unprognostic (1.01e-1)" "unprognostic (2.12e-1)" "unprognostic (1.10e-1)" PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 69.9" "Cell type enhanced" "Detected in many" "Enterocytes: 513.9;Loop of henle epithelial cells: 197.6;Oocytes: 216.4;Prostatic glandular cells: 323.4;Renal collecting duct principal cells: 165.5;Renal connecting tubule cells: 184.7;Retinal horizontal cells: 202.3;Somatotrophs: 191.4" "Cell type enhanced" "Detected in many" "Enterocytes: 513.9;Glandular cells: 323.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 4 "Prostate Adenocarcinoma (TCGA): 97.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "prostate cancer: 40.8" "Adipose subcutaneous - Endothelial cells, Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 3483 "Granulosa cells: 348312.4" "Not detected" "Not detected" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 17 Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: , HPA011978: " "unprognostic (9.94e-2)" "unprognostic (2.11e-2)" "unprognostic (2.61e-1)" "unprognostic (1.92e-2)" "unprognostic (2.84e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-1)" "unprognostic (1.43e-1)" "unprognostic (1.39e-1)" "unprognostic (3.17e-1)" "validated prognostic favorable (5.66e-7)" "validated prognostic favorable (8.31e-6)" "unprognostic (2.06e-2)" "unprognostic (3.00e-2)" "unprognostic (7.19e-3)" "unprognostic (1.03e-1)" "unprognostic (8.61e-2)" "unprognostic (3.25e-1)" "unprognostic (3.05e-2)" "unprognostic (2.24e-1)" "unprognostic (1.10e-3)" "unprognostic (1.62e-2)" "unprognostic (3.11e-2)" "unprognostic (5.90e-2)" "unprognostic (2.23e-1)" "potential prognostic unfavorable (7.06e-5)" "unprognostic (1.89e-2)" "unprognostic (1.94e-3)" "unprognostic (1.86e-1)" "unprognostic (1.59e-1)" "unprognostic (4.06e-2)" PDF ENSG00000258429 "Peptide deformylase, mitochondrial" Q9HBH1 16 69326913-69330588 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Protein biosynthesis" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "skeletal muscle: 21315062.6" HPA063409 Approved Approved Nucleoplasm,Mitochondria "Intracellular and membrane" Enzyme No No "Cluster 45: Eosinophils - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 78: Plasma cells - Antibody production & ER-stress response" 11 Mitochondria Nucleoplasm "HPA063409: " "unprognostic (3.83e-2)" "unprognostic (5.84e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-1)" "unprognostic (2.62e-1)" "unprognostic (1.31e-1)" "unprognostic (2.82e-1)" "unprognostic (1.49e-1)" "unprognostic (4.10e-3)" "unprognostic (7.51e-2)" "unprognostic (9.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.48e-3)" "unprognostic (1.50e-2)" "unprognostic (6.39e-2)" "unprognostic (3.63e-2)" "unprognostic (2.71e-2)" "unprognostic (4.82e-3)" "unprognostic (1.25e-1)" "unprognostic (1.95e-1)" "unprognostic (1.45e-2)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (5.17e-2)" "unprognostic (2.03e-2)" "unprognostic (2.00e-1)" "unprognostic (2.41e-1)" "unprognostic (9.00e-2)" "unprognostic (2.08e-1)" "unprognostic (9.31e-2)" "unprognostic (1.40e-1)" PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 188.3" "Group enriched" "Detected in many" 4 "Decidual stromal cells: 203.7;Endometrial stromal cells: 261.4;Fibroblasts: 245.6;Hepatic stellate cells: 154.9;Leydig cells: 301.5;Oligodendrocyte progenitor cells: 296.2;Ovarian stromal cells: 108.6;Peritubular myoid cells: 333.9" "Group enriched" "Detected in many" 5 "Fibroblasts: 245.6;Glial cells: 296.2;Leydig cells: 301.5;Stellate cells: 154.9;Stromal cells: 333.9" "Group enriched" "Detected in some" 13 "fibroblast: 133.8;oligodendrocyte precursor cell: 320.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 101.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 78.7;thyroid cancer: 38.5" "Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Minor Salivary Gland - Macrophages, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Fallopian tube cells: 84363.7;Glomeruli: 59850.3;Oocytes: 183658.0" "Tissue enriched" "Detected in many" "ovary: 6193217.7" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions,Primary cilium,Cytosol" "Intracellular and membrane" Receptor NA NA 310000 "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 36 "Nucleoplasm, Plasma membrane, Cell Junctions" "Nuclear bodies, Primary cilium, Cytosol" "CAB018143: , HPA004947: " "unprognostic (1.39e-1)" "unprognostic (2.75e-1)" "unprognostic (4.29e-1)" "unprognostic (3.15e-2)" "unprognostic (5.76e-2)" "unprognostic (9.07e-2)" "unprognostic (3.95e-1)" "unprognostic (8.34e-3)" "potential prognostic favorable (6.22e-5)" "unprognostic (2.31e-1)" "unprognostic (3.55e-2)" "unprognostic (3.37e-1)" "unprognostic (1.09e-3)" "unprognostic (7.37e-2)" "unprognostic (4.97e-3)" "unprognostic (1.86e-1)" "unprognostic (2.27e-1)" "unprognostic (1.51e-2)" "unprognostic (1.12e-1)" "unprognostic (1.17e-2)" "unprognostic (3.70e-3)" "unprognostic (9.86e-2)" "unprognostic (6.95e-2)" "unprognostic (8.35e-2)" "unprognostic (2.92e-1)" "unprognostic (3.93e-2)" "unprognostic (1.56e-2)" "unprognostic (6.53e-3)" "unprognostic (3.89e-2)" "unprognostic (1.59e-2)" "unprognostic (3.22e-2)" PDHA1 "E1alpha, PDHA" ENSG00000131828 "Pyruvate dehydrogenase E1 subunit alpha 1" P08559 X 19343893-19361718 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant, Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 239.9;skeletal muscle: 209.1;tongue: 419.9" "Cell type enhanced" "Detected in many" "Oocytes: 690.8;Parietal cells: 284.6" "Cell type enhanced" "Detected in all" "Oocytes: 690.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Cardiomyocytes, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1227478572.6" "Group enriched" "Detected in all" "cerebral cortex: 319749609.8;heart muscle: 817577068.5;skeletal muscle: 334154490.5" "HPA047487, HPA047864, HPA063053" Approved Supported Mitochondria NA NA 37000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 112 Mitochondria "HPA047487: , HPA047864: , HPA063053: " "unprognostic (2.12e-2)" "unprognostic (6.14e-3)" "unprognostic (1.99e-1)" "unprognostic (1.32e-1)" "unprognostic (1.71e-2)" "unprognostic (5.40e-3)" "unprognostic (2.82e-2)" "unprognostic (1.38e-2)" "unprognostic (5.78e-3)" "unprognostic (2.52e-2)" "potential prognostic favorable (5.75e-7)" "unprognostic (1.93e-1)" "potential prognostic favorable (6.01e-4)" "potential prognostic unfavorable (8.63e-4)" "unprognostic (1.80e-2)" "unprognostic (2.05e-2)" "unprognostic (5.88e-2)" "unprognostic (2.46e-2)" "unprognostic (3.85e-2)" "unprognostic (1.73e-1)" "unprognostic (5.10e-3)" "unprognostic (2.00e-1)" "unprognostic (2.85e-1)" "unprognostic (1.85e-2)" "unprognostic (9.35e-2)" "unprognostic (2.89e-1)" "unprognostic (3.30e-2)" "unprognostic (1.35e-1)" "unprognostic (3.54e-1)" "unprognostic (1.60e-2)" "unprognostic (3.54e-1)" PDHA2 PDHAL ENSG00000163114 "Pyruvate dehydrogenase E1 subunit alpha 2" P29803 4 95840093-95841464 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 563 "testis: 56.2" "Group enriched" "Detected in some" 25 "Early spermatids: 370.6;Late primary spermatocytes: 666.6;Late spermatids: 362.2" "Cell type enriched" "Detected in some" 138 "Spermatogenic cell types: 666.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in some" 4907 "Capillaries: 649470.0;Hepatocytes: 331865.8" "Tissue enriched" "Detected in single" 167 "blood vessel: 16712.0" "HPA047487, HPA047864, HPA063053" Approved Supported Nucleoli,Mitochondria NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 1 Mitochondria Nucleoli "HPA047487: , HPA047864: , HPA063053: " PDHB "E1beta, PDHE1B" ENSG00000168291 "Pyruvate dehydrogenase E1 subunit beta" P11177 3 58427630-58433857 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism, Tricarboxylic acid cycle" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 279.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 205.1;Syncytiotrophoblasts: 176.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 455533729.3" "Tissue enhanced" "Detected in all" "heart muscle: 1498256986.8" "CAB033794, HPA036744, HPA036745" Enhanced Supported "Nucleoplasm,Cell Junctions,Mitochondria" No No 26000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 40 Mitochondria "Nucleoplasm, Cell Junctions" "CAB033794: , HPA036744: , HPA036745: " "unprognostic (1.01e-1)" "unprognostic (3.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.23e-1)" "unprognostic (2.45e-3)" "unprognostic (1.22e-1)" "unprognostic (2.11e-1)" "unprognostic (1.90e-1)" "unprognostic (9.15e-2)" "unprognostic (1.89e-2)" "potential prognostic favorable (5.19e-7)" "unprognostic (1.22e-2)" "potential prognostic favorable (1.52e-4)" "unprognostic (4.30e-2)" "unprognostic (1.16e-2)" "unprognostic (9.59e-2)" "unprognostic (4.54e-2)" "unprognostic (6.69e-2)" "unprognostic (4.93e-1)" "unprognostic (4.83e-2)" "unprognostic (2.11e-2)" "unprognostic (2.90e-1)" "unprognostic (4.88e-1)" "unprognostic (6.10e-2)" "unprognostic (2.75e-1)" "unprognostic (9.57e-2)" "unprognostic (5.37e-2)" "unprognostic (1.37e-1)" "unprognostic (1.65e-1)" "unprognostic (2.80e-2)" "unprognostic (4.07e-1)" PDIA3 "ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC" ENSG00000167004 "Protein disulfide isomerase family A member 3" P30101 15 43746394-43773279 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Adaptive immunity, Immunity" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 292.0" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 1120.2;Extravillous trophoblasts: 1162.4;Syncytiotrophoblasts: 1401.4" "Cell type enhanced" "Detected in all" "Trophoblast cells: 1401.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islets: 2014287344.5" "Low tissue specificity" "Detected in all" "HPA002645, HPA003230, CAB011199, CAB015181, CAB075744" Enhanced Enhanced "Endoplasmic reticulum" "Intracellular and membrane" Immunity NA NA 110000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 68 "Endoplasmic reticulum" "CAB011199: , CAB015181: , CAB075744: , HPA002645: , HPA003230: " "unprognostic (8.47e-2)" "unprognostic (1.95e-1)" "unprognostic (3.38e-1)" "unprognostic (1.44e-1)" "unprognostic (2.00e-1)" "unprognostic (1.26e-1)" "unprognostic (7.79e-3)" "unprognostic (9.72e-3)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (3.99e-1)" "unprognostic (5.19e-3)" "potential prognostic unfavorable (6.14e-6)" "unprognostic (3.60e-2)" "unprognostic (4.25e-2)" "potential prognostic unfavorable (8.67e-4)" "unprognostic (8.35e-2)" "unprognostic (1.20e-1)" "unprognostic (1.43e-1)" "unprognostic (1.33e-1)" "unprognostic (1.04e-1)" "unprognostic (9.77e-2)" "unprognostic (9.50e-2)" "unprognostic (4.66e-3)" "unprognostic (2.70e-1)" "unprognostic (2.68e-1)" "unprognostic (6.38e-3)" "unprognostic (1.22e-1)" "unprognostic (4.64e-2)" "unprognostic (2.46e-1)" "unprognostic (2.81e-2)" "unprognostic (1.31e-1)" PDIA6 "ERp5, P5, TXNDC7" ENSG00000143870 "Protein disulfide isomerase family A member 6" Q15084 2 10783391-10837977 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 733.6;Epididymal principal cells: 1039.1;Extravillous trophoblasts: 1634.6;Migrating cytotrophoblasts: 727.0;Plasma cells: 859.0" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 1039.1;Trophoblast cells: 1634.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Pancreas epithelial cells: 1393620187.3;Pancreatic islets: 1364256129.4" "Tissue enriched" "Detected in all" "pancreas: 1091945673.0" "CAB034347, HPA034652, HPA034653" Enhanced Supported "Endoplasmic reticulum,Primary cilium,Centriolar satellite,Basal body" "Intracellular and membrane" Enzyme NA NA 14000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 31 "Endoplasmic reticulum" "Primary cilium, Centriolar satellite, Basal body" "CAB034347: , HPA034652: , HPA034653: " "unprognostic (1.06e-1)" "unprognostic (8.69e-3)" "unprognostic (2.84e-1)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (1.11e-1)" "unprognostic (3.04e-2)" "unprognostic (6.09e-2)" "unprognostic (1.76e-3)" "potential prognostic unfavorable (7.46e-4)" "potential prognostic unfavorable (1.79e-4)" "potential prognostic favorable (5.18e-4)" "unprognostic (2.02e-3)" "unprognostic (6.07e-3)" "validated prognostic unfavorable (1.13e-7)" "validated prognostic unfavorable (1.04e-6)" "unprognostic (4.95e-3)" "unprognostic (4.61e-2)" "unprognostic (1.59e-1)" "unprognostic (8.48e-2)" "unprognostic (2.01e-3)" "unprognostic (3.93e-2)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (9.26e-3)" "unprognostic (2.58e-1)" "unprognostic (2.08e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (8.04e-5)" "unprognostic (3.27e-1)" "unprognostic (1.71e-1)" "unprognostic (2.47e-2)" "unprognostic (1.79e-1)" PDK2 PDHK2 ENSG00000005882 "Pyruvate dehydrogenase kinase 2" Q15119 17 50094737-50112152 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 202.5;tongue: 265.8" "Cell type enhanced" "Detected in many" "Enterocytes: 113.5;Epididymal principal cells: 248.9;Retinal pigment epithelial cells: 110.8" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 248.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Spleen - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34415442.3;Proximal tubules: 25648504.0" "Tissue enhanced" "Detected in many" "heart muscle: 24613693.2" HPA008287 Supported Approved Nucleoplasm,Mitochondria NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 7 "Nucleoplasm, Mitochondria" "HPA008287: " "unprognostic (1.36e-1)" "unprognostic (8.49e-2)" "unprognostic (1.29e-1)" "unprognostic (3.35e-3)" "unprognostic (1.50e-1)" "unprognostic (6.93e-2)" "unprognostic (4.34e-1)" "unprognostic (2.77e-2)" "unprognostic (6.61e-3)" "unprognostic (3.36e-1)" "validated prognostic favorable (1.42e-6)" "validated prognostic favorable (7.17e-5)" "unprognostic (2.08e-3)" "unprognostic (3.00e-2)" "unprognostic (2.84e-2)" "potential prognostic favorable (5.32e-4)" "unprognostic (1.94e-1)" "unprognostic (1.47e-1)" "unprognostic (7.91e-2)" "unprognostic (1.47e-1)" "unprognostic (3.30e-1)" "unprognostic (1.21e-1)" "unprognostic (2.92e-2)" "unprognostic (8.27e-2)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (9.77e-2)" "unprognostic (2.68e-1)" "unprognostic (1.31e-1)" "unprognostic (2.69e-1)" "unprognostic (1.97e-1)" PDK3 ENSG00000067992 "Pyruvate dehydrogenase kinase 3" Q15120 X 24465244-24550466 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 33.6" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 261.8;Neutrophils: 200.7;Sertoli cells: 335.0" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 335.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA046583, HPA072492" Approved Supported Nucleoli,Mitochondria NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 14: Neurons - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 27 Mitochondria Nucleoli "HPA046583: , HPA072492: " "unprognostic (6.29e-2)" "potential prognostic unfavorable (2.69e-5)" "unprognostic (7.06e-2)" "unprognostic (9.88e-2)" "unprognostic (2.87e-2)" "unprognostic (1.64e-1)" "unprognostic (4.31e-2)" "unprognostic (1.16e-2)" "unprognostic (2.40e-2)" "potential prognostic unfavorable (8.49e-5)" "potential prognostic favorable (3.47e-6)" "unprognostic (3.17e-2)" "unprognostic (2.36e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (5.68e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (1.27e-4)" "unprognostic (1.62e-1)" "unprognostic (3.75e-1)" "unprognostic (1.34e-1)" "unprognostic (1.81e-1)" "unprognostic (6.03e-2)" "unprognostic (1.43e-2)" "unprognostic (9.66e-2)" "unprognostic (8.15e-3)" "unprognostic (9.23e-3)" "unprognostic (3.46e-2)" "unprognostic (5.18e-2)" "unprognostic (7.88e-2)" "unprognostic (3.06e-1)" "unprognostic (2.10e-1)" PDLIM2 ENSG00000120913 "PDZ and LIM domain 2" Q96JY6 8 22578279-22598025 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 11.7;Bergmann glia: 17.2;Brain excitatory neurons: 12.9;Enterocytes: 18.5;Ependymal cells: 8.3;Microglia: 7.7;Oligodendrocyte progenitor cells: 8.6;Other brain neurons: 8.8;Podocytes: 11.6;Syncytiotrophoblasts: 7.3;Transitional alveolar cells: 8.1" "Cell type enhanced" "Detected in many" "Enterocytes: 18.5;Glial cells: 17.2;Neuronal cells: 12.9" "Cell type enhanced" "Detected in many" "pericyte: 108.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Stomach - Fibroblasts" "Region enhanced" "Detected in all" "white matter: 429.4" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in many" "Glomeruli: 565282561.6" "Group enriched" "Detected in all" "kidney: 100270468.2;lung: 52962700.8;lymphoid tissue: 122512347.8" HPA003880 Approved Supported "Actin filaments,Focal adhesion sites" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 3 "Actin filaments, Focal adhesion sites" "HPA003880: " "unprognostic (4.96e-2)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (1.26e-1)" "unprognostic (8.15e-2)" "unprognostic (5.42e-2)" "unprognostic (2.02e-2)" "unprognostic (2.43e-1)" "unprognostic (6.11e-2)" "unprognostic (2.12e-1)" "unprognostic (3.38e-3)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (4.46e-6)" "unprognostic (2.97e-1)" "potential prognostic favorable (9.07e-4)" "unprognostic (9.59e-2)" "unprognostic (7.48e-2)" "unprognostic (6.89e-2)" "unprognostic (3.90e-1)" "unprognostic (1.97e-3)" "unprognostic (6.90e-2)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (4.51e-2)" "unprognostic (6.59e-2)" "unprognostic (4.71e-2)" "unprognostic (2.91e-1)" "unprognostic (9.39e-2)" "unprognostic (1.71e-1)" "unprognostic (3.89e-2)" PDP1 "PDH, PDP, PPM2A, PPM2C" ENSG00000164951 "Pyruvate dehydrogenase phosphatase catalytic subunit 1" Q9P0J1 8 93857807-93926068 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 165.4;Cardiomyocytes: 107.2;Early spermatids: 177.8;Endometrial glandular cells: 93.3;Ocular epithelial cells: 90.6;Salivary duct cells: 95.0" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 165.4;Spermatogenic cell types: 177.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Vascular endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 29420430.8" "Low tissue specificity" "Detected in all" "HPA018483, HPA019081, HPA021152" Uncertain Uncertain Nucleoplasm,Vesicles,Mitochondria,Cytosol Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 100: Stratified epithelial cells - Barrier functions" 8 "Nucleoplasm, Cytosol" "Vesicles, Mitochondria" "HPA018483: , HPA019081: , HPA021152: " "unprognostic (2.63e-2)" "potential prognostic unfavorable (2.63e-5)" "unprognostic (3.14e-1)" "unprognostic (2.70e-2)" "unprognostic (1.50e-1)" "unprognostic (2.99e-1)" "unprognostic (1.90e-1)" "unprognostic (7.15e-2)" "unprognostic (1.51e-1)" "unprognostic (1.44e-1)" "potential prognostic favorable (8.42e-6)" "unprognostic (1.56e-2)" "unprognostic (7.50e-3)" "unprognostic (1.69e-1)" "unprognostic (1.54e-1)" "unprognostic (2.17e-1)" "unprognostic (1.46e-2)" "unprognostic (7.61e-2)" "unprognostic (4.40e-1)" "validated prognostic unfavorable (1.11e-5)" "validated prognostic unfavorable (2.34e-4)" "unprognostic (8.36e-3)" "unprognostic (2.66e-3)" "unprognostic (2.56e-1)" "unprognostic (5.82e-2)" "unprognostic (1.08e-1)" "unprognostic (1.53e-1)" "unprognostic (9.23e-2)" "unprognostic (2.52e-1)" "unprognostic (1.71e-1)" "unprognostic (3.06e-2)" PDPN "aggrus, D2-40, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins, Transporters" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 108.9;Breast myoepithelial cells: 85.2;Decidual stromal cells: 204.4;Epicardial cells: 170.6;Epididymal basal cells: 98.5;Fibroblasts: 145.2;Lymphatic endothelial cells: 175.0;Mesothelial cells: 167.1;Müller glia: 119.6;Oocytes: 92.1;Ovarian stromal cells: 93.2;Peritubular myoid cells: 72.0;Retinal pigment epithelial cells: 102.3;Salivary myoepithelial cells: 95.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 170.6;Endothelial cells: 175.0;Fibroblasts: 145.2;Stromal cells: 204.4" "Group enriched" "Detected in many" 6 "astrocyte: 19.5;Bergmann glia: 26.1;central nervous system macrophage: 31.6;choroid plexus epithelial cell: 40.0;ependymal cell: 24.2;fibroblast: 21.6;oligodendrocyte precursor cell: 40.4" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 216.3;Testicular Germ Cell Tumor (TCGA): 288.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 109.6;thyroid cancer: 97.5" "Kidney - Podocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enhanced" "Detected in some" "ovary: 1163407.2" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 1 "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: , HPA007534: , HPA007949: " "unprognostic (1.31e-2)" "unprognostic (2.88e-1)" "unprognostic (5.46e-2)" "unprognostic (4.03e-2)" "unprognostic (3.82e-2)" "unprognostic (1.83e-1)" "unprognostic (3.41e-2)" "potential prognostic unfavorable (4.86e-7)" "unprognostic (3.34e-3)" "unprognostic (5.73e-2)" "unprognostic (4.78e-3)" "unprognostic (1.93e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-2)" "unprognostic (1.70e-1)" "unprognostic (1.50e-1)" "unprognostic (4.54e-2)" "unprognostic (6.44e-2)" "unprognostic (1.29e-1)" "unprognostic (5.75e-2)" "unprognostic (2.17e-2)" "unprognostic (1.07e-2)" "unprognostic (2.60e-1)" "unprognostic (6.07e-2)" "unprognostic (3.95e-1)" "unprognostic (5.39e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (5.24e-4)" "unprognostic (1.80e-1)" "unprognostic (2.88e-2)" "unprognostic (3.14e-2)" PDSS2 "bA59I9.3, C6orf210, COQ1B" ENSG00000164494 "Decaprenyl diphosphate synthase subunit 2" Q86YH6 6 107152562-107459564 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Isoprene biosynthesis, Lipid metabolism, Ubiquinone biosynthesis" Transferase "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 6767759.3" "Group enriched" "Detected in many" "liver: 624170.8;lymphoid tissue: 240292.4" "HPA029685, HPA029686" Approved Supported Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 1 Cytosol "HPA029685: , HPA029686: " "unprognostic (6.05e-2)" "validated prognostic unfavorable (4.97e-5)" "validated prognostic unfavorable (3.29e-6)" "unprognostic (2.45e-2)" "unprognostic (2.05e-2)" "potential prognostic favorable (3.45e-4)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (1.09e-1)" "unprognostic (7.52e-3)" "validated prognostic favorable (6.86e-7)" "validated prognostic favorable (6.76e-5)" "potential prognostic favorable (4.09e-4)" "unprognostic (1.20e-1)" "unprognostic (7.74e-2)" "unprognostic (2.15e-1)" "unprognostic (2.71e-1)" "unprognostic (1.21e-1)" "unprognostic (3.72e-1)" "unprognostic (1.52e-1)" "unprognostic (5.97e-2)" "unprognostic (1.65e-1)" "unprognostic (1.19e-1)" "unprognostic (1.70e-1)" "potential prognostic favorable (1.77e-5)" "unprognostic (1.32e-1)" "unprognostic (8.54e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" PDX1 "GSF, IDX-1, IPF1, IUF-1, MODY4, PDX-1, STF-1" ENSG00000139515 "Pancreatic and duodenal homeobox 1" P52945 13 27920000-27926313 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "intestine: 39.4;pancreas: 12.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 17.2;Foveolar cells: 5.7;Gastric chief cells: 3.3;Gastric progenitor cells: 10.3;Neuroendocrine cells: 10.6;Pancreatic acinar cells: 3.4;Pancreatic duct cells: 24.9;Pancreatic islet cells: 18.4" "Cell type enhanced" "Detected in some" "Ductal cells: 24.9;Enteroendocrine cells: 10.6;Gastric glandular cells: 5.7;Pancreatic islet cells: 18.4;Proliferating cells: 10.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Colon Adenocarcinoma (TCGA): 11.1;Pancreatic Adenocarcinoma (TCGA): 11.7;Rectum Adenocarcinoma (TCGA): 11.2;Stomach Adenocarcinoma (TCGA): 10.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.2;Gastric cancer: 6.1" "Colon - Colon enterocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 7010 "Pancreatic islets: 700968.2" "Not detected" "Not detected" "CAB025873, HPA059146" Enhanced Supported Nucleoplasm NA NA "Cluster 60: Stomach - Digestion" "Cluster 59: Leukemia - T-cell receptor" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 6 Nucleoplasm "CAB025873: , HPA059146: " "unprognostic (1.53e-1)" "unprognostic (5.56e-1)" "unprognostic (3.57e-1)" "unprognostic (3.22e-2)" "unprognostic (4.31e-2)" "unprognostic (6.85e-2)" "unprognostic (1.52e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "unprognostic (5.73e-2)" "unprognostic (9.86e-2)" "unprognostic (1.38e-1)" PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.6" "Cell type enhanced" "Detected in many" "Adipocytes: 797.9;Cardiomyocytes: 875.8;Choroid plexus epithelial cells: 2846.4;Cone photoreceptor cells: 772.2;Oligodendrocyte progenitor cells: 1244.7;Proximal tubule cells: 1410.4;Rod photoreceptor cells: 745.2" "Cell type enhanced" "Detected in all" "Ciliated cells: 2846.4;Glial cells: 1244.7;Renal nephron cells: 1410.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2518.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 1" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 2411582.9" "Group enriched" "Detected in some" 12864 "cerebral cortex: 1689211.2;lung: 883570.9" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" "Cell adhesion" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "Plasma membrane, Cytosol" "CAB020784: , HPA036503: , HPA036504: , HPA064387: , HPA076072: " "unprognostic (1.13e-1)" "unprognostic (1.21e-1)" "unprognostic (1.28e-2)" "unprognostic (3.32e-2)" "unprognostic (9.98e-2)" "unprognostic (2.59e-3)" "unprognostic (4.70e-3)" "unprognostic (7.44e-3)" "potential prognostic favorable (2.26e-8)" "unprognostic (3.60e-3)" "unprognostic (1.33e-2)" "unprognostic (3.61e-2)" "unprognostic (1.28e-2)" "unprognostic (3.54e-1)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (3.25e-1)" "unprognostic (3.42e-2)" "unprognostic (1.06e-1)" "unprognostic (2.07e-2)" "unprognostic (3.42e-2)" PDZD7 "bA108L7.8, DFNB57, FLJ23209, PDZK7" ENSG00000186862 "PDZ domain containing 7" Q9H5P4 10 101007679-101032295 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 21.2;intestine: 18.8;pituitary gland: 7.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 29.3;Brain inhibitory neurons: 28.0;Enterocytes: 88.4;Gonadotrophs: 33.2;Other brain neurons: 16.5;Podocytes: 16.8;Retinal amacrine cells: 26.9;Retinal ganglion cells: 38.6" "Cell type enhanced" "Detected in many" "Enterocytes: 88.4;Neuronal cells: 38.6;Pituitary endocrine cells: 33.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA074542 Approved "Nucleoplasm,Primary cilium,Basal body" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Nucleoplasm, Primary cilium" "Basal body" "HPA074542: " "unprognostic (1.37e-2)" "unprognostic (2.17e-2)" "unprognostic (1.72e-1)" "unprognostic (3.59e-2)" "unprognostic (3.40e-3)" "unprognostic (4.75e-2)" "unprognostic (7.53e-2)" "unprognostic (7.70e-2)" "unprognostic (1.18e-3)" "unprognostic (2.42e-2)" "unprognostic (1.30e-1)" "unprognostic (2.26e-1)" "unprognostic (1.24e-3)" "unprognostic (5.41e-2)" "unprognostic (6.23e-2)" "unprognostic (4.86e-2)" "unprognostic (2.62e-2)" "unprognostic (4.62e-1)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (1.98e-2)" "potential prognostic favorable (1.37e-4)" "unprognostic (2.85e-1)" "unprognostic (7.02e-2)" "unprognostic (2.14e-1)" "unprognostic (7.31e-3)" "unprognostic (6.55e-2)" PDZK1 "NHERF3, PDZD1" ENSG00000174827 "PDZ domain containing 1" Q5T2W1 1 145670852-145708148 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "kidney: 556.3" "Cell type enhanced" "Detected in many" "Cholangiocytes: 84.8;Enterocytes: 325.2;Epididymal efferent duct absorptive cells: 102.4;Hepatocytes: 63.3;Loop of henle epithelial cells: 50.1;Proximal tubule cells: 390.5" "Group enriched" "Detected in many" 4 "Ductal cells: 102.4;Enterocytes: 325.2;Renal nephron cells: 390.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 22.4;upper rhombic lip: 24.4" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 180.3;Kidney Renal Papillary Cell Carcinoma (TCGA): 190.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "NK-cell: 4.2" "Lineage enriched" "Detected in single" 5 "NK-cells: 4.2" "Cancer enhanced" "Detected in many" "Kidney cancer: 108.6" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "Glomeruli: 279527350.4;Proximal tubules: 436705063.9" "Tissue enriched" "Detected in some" "kidney: 504705323.1" "HPA005755, HPA006155, CAB008971" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 66000 "Cluster 14: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 27: Breast cancer - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 23 "Nucleoplasm, Vesicles" Cytosol "CAB008971: , HPA005755: , HPA006155: " "unprognostic (3.66e-2)" "unprognostic (9.21e-3)" "unprognostic (1.07e-1)" "unprognostic (5.44e-2)" "unprognostic (9.97e-2)" "unprognostic (1.55e-1)" "unprognostic (9.90e-2)" "unprognostic (7.57e-3)" "unprognostic (3.34e-1)" "unprognostic (2.17e-1)" "validated prognostic favorable (1.30e-9)" "validated prognostic favorable (8.22e-4)" "unprognostic (1.61e-2)" "unprognostic (2.32e-1)" "unprognostic (2.76e-2)" "unprognostic (2.17e-1)" "unprognostic (1.98e-1)" "unprognostic (3.53e-2)" "unprognostic (1.28e-1)" "unprognostic (3.43e-2)" "unprognostic (1.10e-1)" "unprognostic (1.75e-1)" "unprognostic (2.85e-1)" "unprognostic (1.84e-1)" PDZRN3 "KIAA1095, LNX3, SEMACAP3, SEMCAP3" ENSG00000121440 "PDZ domain containing ring finger 3" Q9UPQ7 3 73382431-73624941 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 1163.3;Adrenal cortex cells: 882.7;Cardiomyocytes: 1323.3;Choroid plexus epithelial cells: 3031.7;Endometrial stromal cells: 836.7;Myonuclei: 624.5;Prostatic glandular cells: 586.7" "Cell type enhanced" "Detected in many" "Adipocytes: 1163.3;Ciliated cells: 3031.7;Myocytes: 1323.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2398.4;fibroblast: 2333.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "plasmacytoid DC: 1.9" "Lineage enriched" "Detected in single" 19 "dendritic cells: 1.9" "Cancer enhanced" "Detected in many" "Neuroblastoma: 23.9;skin cancer: 17.9" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Heart muscle - Cardiomyocytes, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes, Skin - Outer root sheath cells, Spleen - Fibroblasts_1" "Group enriched" "Detected in many" 4 "amygdala: 15.2;basal ganglia: 8.1;cerebral cortex: 19.5;hippocampal formation: 16.1;white matter: 7.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "Granulosa cells: 5274034.0;Smooth muscle cells: 4260443.4" "Tissue enriched" "Detected in single" 25309 "skeletal muscle: 2530917.5" "HPA038822, HPA061420" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 9 Cytosol Nucleoplasm "HPA038822: , HPA061420: " "unprognostic (5.34e-2)" "unprognostic (2.29e-2)" "unprognostic (6.29e-2)" "unprognostic (7.46e-3)" "unprognostic (1.31e-1)" "unprognostic (1.34e-1)" "unprognostic (2.83e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (5.31e-2)" "validated prognostic favorable (5.28e-8)" "validated prognostic favorable (6.79e-4)" "unprognostic (1.45e-3)" "unprognostic (1.73e-1)" "unprognostic (8.40e-3)" "unprognostic (9.31e-2)" "unprognostic (4.83e-1)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (6.84e-4)" "unprognostic (1.51e-3)" "unprognostic (3.44e-1)" "unprognostic (1.53e-1)" "unprognostic (4.52e-2)" "unprognostic (3.68e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-2)" "unprognostic (1.77e-1)" "unprognostic (4.45e-2)" "unprognostic (2.45e-3)" PDZRN4 "DKFZp434B0417, FLJ33777, IMAGE5767589, LNX4" ENSG00000165966 "PDZ domain containing ring finger 4" Q6ZMN7 12 41188320-41574745 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 14.3;intestine: 14.6;seminal vesicle: 16.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 615.3;Corticotrophs: 586.8;Fibro-adipogenic progenitors: 359.6;Fibroblasts: 398.1;Gonadotrophs: 281.5;Granulosa cells: 279.0;Lactotrophs: 366.2;Leydig cells: 913.7;Mesothelial cells: 349.2;Oligodendrocyte progenitor cells: 962.1;Peritubular myoid cells: 1469.3;Retinal bipolar cells: 415.4;Smooth muscle cells: 496.1;Vascular smooth muscle cells: 396.6" "Cell type enhanced" "Detected in many" "Glial cells: 962.1;Leydig cells: 913.7;Pituitary endocrine cells: 586.8;Stromal cells: 1469.3" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 1015.3;oligodendrocyte precursor cell: 1133.5" "Cancer enhanced" "Detected in some" "Kidney Chromophobe (TCGA): 5.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 1.3;ovarian cancer: 1.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Smooth muscle cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Skin - Fibroblasts_2, Spleen - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4537 "Granulosa cells: 453691.4" "Not detected" "Not detected" HPA042101 Enhanced Approved Mitochondria NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" Mitochondria "HPA042101: " "unprognostic (1.97e-1)" "unprognostic (1.97e-1)" "unprognostic (1.76e-2)" "unprognostic (1.16e-1)" "unprognostic (3.53e-3)" "unprognostic (1.07e-1)" "unprognostic (1.48e-3)" "unprognostic (4.09e-2)" PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916429 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 4 "Platelets: 316.1" "Cell type enriched" "Detected in many" 4 "Platelets: 316.1" "Group enriched" "Detected in some" 39 "endothelial cell: 41.6;fibroblast: 45.2;pericyte: 113.4;vascular associated smooth muscle cell: 51.5" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 6.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.4" "Adipose subcutaneous - Endothelial cells, Adrenal gland - Fibroblasts, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Fibroblasts, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5205 "Macrophages: 520532.6" "Tissue enhanced" "Detected in some" "lymphoid tissue: 1224066.2;ovary: 548671.9" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centriolar satellite" NA NA 11000000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 47: Platelets - Hemostasis" 2 "Nucleoplasm, Cell Junctions, Centriolar satellite" "HPA035217: " "unprognostic (1.67e-1)" "unprognostic (2.16e-1)" "unprognostic (8.85e-2)" "unprognostic (7.79e-2)" "unprognostic (1.52e-1)" "unprognostic (5.63e-2)" "unprognostic (2.29e-1)" "validated prognostic favorable (5.88e-6)" "validated prognostic favorable (7.29e-4)" "potential prognostic favorable (9.65e-5)" "unprognostic (1.78e-2)" "unprognostic (7.15e-2)" "unprognostic (2.97e-2)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (5.74e-4)" "unprognostic (9.18e-2)" "unprognostic (2.64e-1)" "unprognostic (2.16e-3)" "unprognostic (2.38e-2)" "unprognostic (4.22e-3)" PEG10 "HB-1, KIAA1051, Mar2, Mart2, MEF3L, RGAG3, RTL2, SIRH1" ENSG00000242265 "Paternally expressed 10" Q86TG7 7 94656325-94669695 "Predicted intracellular proteins" "Apoptosis, Differentiation, Transport" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 162.5;placenta: 439.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 505.2;Corticotrophs: 1028.1;Cytotrophoblasts: 2584.1;Gonadotrophs: 933.2;Migrating cytotrophoblasts: 1309.9;Other brain neurons: 444.7;Pancreatic islet cells: 425.3;Syncytiotrophoblasts: 2986.8;Transitional alveolar cells: 537.7" "Cell type enhanced" "Detected in many" "Alveolar cells: 537.7;Pituitary endocrine cells: 1028.1;Trophoblast cells: 2986.8" "Cell type enhanced" "Detected in all" "eccentric medium spiny neuron: 216.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells" "Region enhanced" "Detected in all" "hypothalamus: 110.8" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 390974.3;Hepatocytes: 552031.4;Oocytes: 596962.6" "Tissue enriched" "Detected in some" "lung: 692405.8" "HPA021324, HPA029915, HPA051038" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 18: Liver cancer - Metabolism" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 32 Cytosol Nucleoplasm "HPA021324: , HPA029915: , HPA051038: " "unprognostic (8.25e-2)" "unprognostic (2.37e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-2)" "unprognostic (8.68e-2)" "unprognostic (1.43e-1)" "unprognostic (2.73e-1)" "unprognostic (5.74e-2)" "unprognostic (8.07e-3)" "unprognostic (7.83e-3)" "potential prognostic favorable (6.80e-4)" "unprognostic (3.53e-2)" "potential prognostic unfavorable (3.29e-6)" "unprognostic (3.45e-3)" "potential prognostic unfavorable (2.59e-4)" "unprognostic (1.12e-1)" "unprognostic (3.70e-2)" "unprognostic (5.43e-2)" "unprognostic (1.17e-1)" "unprognostic (9.14e-2)" "unprognostic (9.75e-2)" "unprognostic (3.08e-2)" "potential prognostic unfavorable (2.50e-6)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (2.74e-2)" "unprognostic (1.63e-1)" "unprognostic (4.95e-3)" "unprognostic (1.57e-1)" "unprognostic (8.12e-2)" "unprognostic (2.50e-1)" PEG3 "KIAA0287, ZKSCAN22, ZNF904, ZSCAN24" ENSG00000198300 "Paternally expressed 3" Q9GZU2 19 56810077-56840728 "Predicted intracellular proteins, Transcription factors" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 195.7;placenta: 126.9" "Cell type enhanced" "Detected in some" "Brain inhibitory neurons: 4.6;Cytotrophoblasts: 14.5;Early primary spermatocytes: 4.4;Gonadotrophs: 16.3;Late spermatids: 5.0;Migrating cytotrophoblasts: 13.4;Other brain neurons: 6.4;Ovarian stromal cells: 5.5;Retinal horizontal cells: 6.0;Syncytiotrophoblasts: 23.3" "Cell type enhanced" "Detected in some" "Neuronal cells: 6.4;Pituitary endocrine cells: 16.3;Trophoblast cells: 23.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 16.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 62.9;Rhabdoid: 163.0" "Adrenal gland - Adrenal cortex cells, Pituitary gland - Gonadotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 2993412.4;Oocytes: 2728464.2" "Tissue enriched" "Detected in single" 69151 "ovary: 6915055.0" HPA026070 Approved Approved Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 4 Nucleoplasm "HPA026070: " "unprognostic (1.67e-2)" "unprognostic (1.17e-2)" "unprognostic (1.68e-1)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "unprognostic (1.86e-2)" "unprognostic (4.38e-2)" "unprognostic (2.75e-2)" "unprognostic (5.34e-2)" "unprognostic (1.23e-1)" "unprognostic (6.49e-3)" "unprognostic (2.23e-2)" "unprognostic (2.99e-1)" "unprognostic (2.68e-1)" "unprognostic (1.42e-2)" "unprognostic (3.41e-1)" "unprognostic (1.49e-1)" "unprognostic (6.21e-3)" "unprognostic (3.65e-2)" "unprognostic (2.27e-2)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (5.78e-4)" PELI1 ENSG00000197329 "Pellino E3 ubiquitin protein ligase 1" Q96FA3 2 64092652-64144420 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 215.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1029.4;Esophageal apical cells: 1054.5;monocytes: 870.9;Neutrophils: 4332.1;Plasma cells: 1723.1;Transitional alveolar cells: 913.3" "Cell type enhanced" "Detected in all" "Neutrophils: 4332.1;Plasma cells: 1723.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 534.7;endothelial cell: 794.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 77.1" "Group enriched" "Detected in all" 4 "granulocytes: 77.1;monocytes: 23.3" "Cancer enhanced" "Detected in all" "lymphoma: 51.0" "Kidney - Endothelial cells, Liver - Neutrophils, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA053182 Approved Supported "Nucleoplasm,Nucleoli,Intermediate filaments,Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 37 "Nucleoplasm, Nucleoli, Basal body" "Intermediate filaments, Centriolar satellite, Centrosome, Cytosol" "HPA053182: " "unprognostic (1.67e-1)" "unprognostic (2.24e-1)" "unprognostic (7.52e-3)" "unprognostic (1.95e-1)" "unprognostic (2.29e-1)" "unprognostic (8.53e-2)" "unprognostic (1.38e-1)" "unprognostic (5.38e-3)" "unprognostic (2.59e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.70e-4)" "unprognostic (5.46e-3)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.48e-2)" "unprognostic (2.59e-1)" "unprognostic (6.91e-2)" "unprognostic (7.61e-2)" "unprognostic (3.67e-2)" "unprognostic (1.08e-1)" "unprognostic (2.03e-2)" "unprognostic (7.98e-3)" "unprognostic (1.51e-3)" "unprognostic (1.88e-1)" "unprognostic (3.12e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" "unprognostic (9.19e-2)" "unprognostic (4.08e-2)" "unprognostic (1.18e-1)" "unprognostic (1.07e-1)" PELI2 ENSG00000139946 "Pellino E3 ubiquitin protein ligase family member 2" Q9HAT8 14 56117814-56301524 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1062.9;Pancreatic acinar cells: 709.2" "Cell type enhanced" "Detected in many" "Neutrophils: 1062.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 5.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Stomach - Gastric mucous cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal tubules: 746745.4;Pancreatic islets: 310430.8" "Not detected" "Not detected" HPA053182 Uncertain Approved "Nucleoplasm,Nucleoli,Intermediate filaments,Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 29 "Nucleoplasm, Nucleoli, Basal body" "Intermediate filaments, Centriolar satellite, Centrosome, Cytosol" "HPA053182: " "unprognostic (6.81e-3)" "unprognostic (3.42e-1)" "unprognostic (1.02e-1)" "unprognostic (1.86e-1)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (7.98e-2)" "unprognostic (1.25e-2)" "unprognostic (3.36e-1)" "unprognostic (5.50e-2)" "validated prognostic favorable (8.33e-9)" "validated prognostic favorable (4.48e-4)" "unprognostic (3.34e-2)" "unprognostic (1.51e-2)" "unprognostic (2.53e-1)" "unprognostic (3.14e-2)" "potential prognostic favorable (8.44e-4)" "unprognostic (7.98e-3)" "unprognostic (2.71e-1)" "unprognostic (2.67e-1)" "unprognostic (1.70e-2)" "unprognostic (4.23e-1)" "unprognostic (1.10e-1)" "unprognostic (4.99e-2)" "unprognostic (7.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.58e-1)" "unprognostic (2.60e-2)" "unprognostic (1.29e-2)" PENK ENSG00000181195 Proenkephalin P01210 8 56436674-56446671 "Plasma proteins, Predicted secreted proteins, Transporters" "Endorphin, Neuropeptide, Opioid peptide" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 355.7;brain: 673.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 372.3;Brain inhibitory neurons: 114.2;Early primary spermatocytes: 128.7;Early spermatids: 67.1;Late primary spermatocytes: 456.2;Leydig cells: 922.0;Peritubular myoid cells: 213.7" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 372.3;Leydig cells: 922.0;Spermatogenic cell types: 456.2;Stromal cells: 213.7" "Group enriched" "Detected in many" 5 "eccentric medium spiny neuron: 116.6;medium spiny neuron: 341.4" "Cancer enhanced" "Detected in many" "Lung Squamous Cell Carcinoma (TCGA): 34.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Rhabdoid: 795.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Early spermatids" "Region enriched" "Detected in all" 7 "basal ganglia: 3628.7" "Region enriched" "Detected in all" 7 "basal ganglia: 1199.3" "Not detected" "Not detected" "Group enriched" "Detected in some" "intestine: 32202816.4;Stomach: 34251314.0" "HPA013138, CAB016390" Enhanced Approved Vesicles "Secreted in other tissues" Neuropeptide NA NA 130000 "Cluster 40: Monocytes - Innate immune response" "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" Vesicles "CAB016390: , HPA013138: " "unprognostic (4.43e-2)" "unprognostic (1.31e-2)" "unprognostic (3.59e-1)" "unprognostic (2.17e-2)" "unprognostic (6.48e-3)" "unprognostic (2.52e-2)" "unprognostic (3.78e-2)" "unprognostic (5.93e-2)" "unprognostic (9.49e-2)" "unprognostic (2.75e-1)" "unprognostic (1.27e-1)" "unprognostic (3.00e-1)" "unprognostic (3.93e-2)" "unprognostic (1.71e-1)" "unprognostic (4.29e-2)" "unprognostic (1.85e-3)" "unprognostic (1.96e-1)" "unprognostic (3.48e-2)" "unprognostic (3.95e-2)" PEPD ENSG00000124299 "Peptidase D" P12955 19 33386950-33521823 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Collagen degradation" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 201.1;kidney: 310.3" "Cell type enhanced" "Detected in many" "Enterocytes: 849.5;Hepatocytes: 210.4;Hofbauer cells: 394.7;Proximal tubule cells: 197.1" "Cell type enhanced" "Detected in all" "Enterocytes: 849.5;Mononuclear phagocytes: 394.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Macrophages, Pancreas - Macrophages, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Glomeruli: 197184061.5;Proximal tubules: 185874842.1" "Group enriched" "Detected in all" "intestine: 260437145.3;kidney: 320851071.8" "HPA015599, HPA072045" Enhanced Approved Nucleoplasm NA NA 250000000 "Cluster 33: Non-specific - ATP binding" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 1: Enterocytes - Absorption and Digestion" 3 Nucleoplasm "HPA015599: , HPA072045: " "unprognostic (4.73e-3)" "unprognostic (1.53e-1)" "unprognostic (2.74e-1)" "unprognostic (5.38e-1)" "unprognostic (3.39e-1)" "unprognostic (2.90e-2)" "unprognostic (2.25e-1)" "unprognostic (8.73e-3)" "unprognostic (2.83e-1)" "unprognostic (2.86e-1)" "potential prognostic favorable (1.87e-7)" "unprognostic (1.48e-1)" "unprognostic (6.23e-2)" "unprognostic (2.40e-1)" "unprognostic (1.52e-2)" "unprognostic (3.49e-1)" "unprognostic (9.54e-2)" "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (7.14e-2)" "unprognostic (9.27e-2)" "unprognostic (1.04e-2)" "unprognostic (6.66e-2)" "unprognostic (3.80e-1)" "unprognostic (1.15e-1)" "unprognostic (2.76e-2)" "unprognostic (7.74e-2)" "unprognostic (2.38e-2)" "unprognostic (1.97e-1)" "unprognostic (1.23e-1)" "unprognostic (2.10e-1)" PER2 KIAA0347 ENSG00000132326 "Period circadian regulator 2" O15055 2 238244044-238290102 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory basal cells: 338.0;Respiratory secretory cells: 282.8;Salivary basal cells: 290.3;Salivary myoepithelial cells: 278.1" "Cell type enhanced" "Detected in many" "Basal cells: 338.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053136, HPA060510" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 21: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 54: Non-specific - Transcription" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 27 Nucleoplasm Cytosol "HPA053136: , HPA060510: " "unprognostic (1.23e-2)" "unprognostic (1.91e-1)" "unprognostic (2.56e-1)" "unprognostic (3.02e-1)" "unprognostic (3.83e-1)" "unprognostic (1.33e-1)" "unprognostic (3.55e-1)" "unprognostic (1.08e-1)" "unprognostic (1.57e-3)" "unprognostic (4.68e-2)" "potential prognostic favorable (1.29e-5)" "unprognostic (2.16e-3)" "unprognostic (5.52e-2)" "unprognostic (3.68e-2)" "unprognostic (2.07e-1)" "unprognostic (1.09e-1)" "unprognostic (1.00e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (2.12e-5)" "unprognostic (5.12e-2)" "unprognostic (4.66e-2)" "unprognostic (7.31e-2)" "unprognostic (1.92e-1)" "unprognostic (6.81e-2)" "unprognostic (1.53e-1)" "unprognostic (1.28e-1)" "unprognostic (1.84e-3)" "unprognostic (3.60e-1)" "unprognostic (2.75e-2)" "unprognostic (6.87e-2)" "unprognostic (1.43e-1)" PES1 "NOP7, PES" ENSG00000100029 "Pescadillo ribosomal biogenesis factor 1" O00541 22 30576625-30607083 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 38.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "Stomach: 8455601.0" "HPA040210, HPA062439, HPA066670" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 58 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA040210: , HPA062439: , HPA066670: " "unprognostic (1.48e-1)" "unprognostic (1.78e-1)" "unprognostic (1.07e-1)" "unprognostic (1.78e-2)" "unprognostic (2.09e-1)" "unprognostic (1.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.51e-1)" "unprognostic (1.60e-3)" "unprognostic (3.57e-2)" "unprognostic (2.44e-2)" "unprognostic (1.04e-1)" "unprognostic (1.08e-2)" "validated prognostic unfavorable (8.03e-10)" "validated prognostic unfavorable (1.40e-5)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (2.55e-3)" "unprognostic (3.15e-2)" "unprognostic (1.86e-3)" "unprognostic (2.89e-1)" "unprognostic (1.18e-1)" "unprognostic (1.05e-2)" "unprognostic (3.70e-2)" "unprognostic (1.53e-1)" "unprognostic (1.26e-3)" "unprognostic (4.19e-2)" "unprognostic (7.97e-2)" "unprognostic (6.89e-2)" "unprognostic (2.21e-1)" "unprognostic (9.64e-2)" "unprognostic (1.81e-2)" PFKM "PFK-1, PFKX, PPP1R122" ENSG00000152556 "Phosphofructokinase, muscle" P08237 12 48105139-48146404 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 1472.3;tongue: 1300.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 239.5;Late primary spermatocytes: 94.5;Müller glia: 114.9;Myonuclei: 175.1;Thymic myoid cells: 407.9" "Cell type enhanced" "Detected in all" "Myocytes: 239.5;Stromal cells: 407.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Capillaries: 683351455.6;Cardiomyocytes: 868036035.8;Skeletal myofibers: 2045202429.0" "Group enriched" "Detected in all" "cerebral cortex: 270428179.1;heart muscle: 372078171.3;skeletal muscle: 543143775.4" HPA002117 Approved Approved "Endoplasmic reticulum,Principal piece" NA NA 240000 "Cluster 29: Non-specific - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 15 "Endoplasmic reticulum" "Principal piece" "HPA002117: " "unprognostic (1.18e-1)" "unprognostic (5.58e-3)" "unprognostic (2.83e-1)" "unprognostic (6.97e-3)" "unprognostic (2.78e-1)" "unprognostic (2.42e-2)" "unprognostic (2.76e-1)" "unprognostic (4.73e-3)" "potential prognostic unfavorable (6.74e-4)" "unprognostic (5.66e-3)" "potential prognostic favorable (1.44e-8)" "unprognostic (6.92e-2)" "unprognostic (1.29e-3)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (2.71e-2)" "unprognostic (1.36e-1)" "unprognostic (3.22e-1)" "unprognostic (8.52e-2)" "unprognostic (1.06e-1)" "unprognostic (1.17e-1)" "unprognostic (2.73e-2)" "unprognostic (2.49e-2)" "unprognostic (3.34e-2)" "unprognostic (1.23e-1)" "unprognostic (3.55e-1)" "unprognostic (3.31e-1)" "unprognostic (1.94e-1)" "unprognostic (6.91e-2)" "unprognostic (5.13e-2)" "unprognostic (8.43e-2)" PFKP "PFK-C, PFKF" ENSG00000067057 "Phosphofructokinase, platelet" Q01813 10 3066333-3137718 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 250.0" "Cell type enhanced" "Detected in many" "Early spermatids: 202.0;Late primary spermatocytes: 241.3;Late spermatids: 287.5;Müller glia: 186.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 287.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia and Neuropil: 159455868.9" "Tissue enriched" "Detected in all" "cerebral cortex: 280681474.6" "HPA018257, HPA056484" Uncertain Supported Cytosol No No 1400000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 45 Cytosol "HPA018257: , HPA056484: " "unprognostic (3.65e-2)" "unprognostic (1.38e-1)" "unprognostic (6.80e-2)" "unprognostic (5.20e-3)" "unprognostic (2.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (1.46e-3)" "potential prognostic favorable (1.09e-6)" "unprognostic (6.00e-2)" "unprognostic (8.11e-2)" "potential prognostic unfavorable (3.15e-5)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (2.00e-5)" "unprognostic (2.79e-2)" "unprognostic (6.67e-2)" "unprognostic (1.52e-1)" "unprognostic (9.97e-2)" "unprognostic (1.40e-1)" "unprognostic (1.12e-2)" "unprognostic (1.79e-2)" "unprognostic (1.96e-2)" "unprognostic (2.14e-1)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" "unprognostic (5.16e-2)" "unprognostic (2.53e-1)" "unprognostic (2.44e-1)" "unprognostic (1.56e-1)" PGAM1 "PGAM-B, PGAMA" ENSG00000171314 "Phosphoglycerate mutase 1" P18669 10 97426191-97433444 "Candidate cardiovascular disease genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 175.7;Suprabasal keratinocytes: 127.4" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 175.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA042528, HPA060483" Approved Approved "Nucleoplasm,Mid piece" NA NA 33000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 97: Non-specific - Cellular respiration" 18 Nucleoplasm "Mid piece" "HPA042528: , HPA060483: " "unprognostic (2.50e-3)" "potential prognostic unfavorable (5.65e-4)" "unprognostic (2.89e-1)" "unprognostic (1.67e-2)" "unprognostic (1.40e-1)" "unprognostic (2.02e-1)" "unprognostic (2.45e-1)" "unprognostic (1.50e-1)" "unprognostic (7.00e-3)" "unprognostic (1.62e-1)" "potential prognostic favorable (6.31e-5)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (6.82e-3)" "unprognostic (2.25e-3)" "validated prognostic unfavorable (8.26e-7)" "validated prognostic unfavorable (8.47e-5)" "unprognostic (1.27e-1)" "unprognostic (9.30e-3)" "unprognostic (5.48e-2)" "unprognostic (9.56e-2)" "unprognostic (5.98e-2)" "unprognostic (1.47e-2)" "unprognostic (9.46e-3)" "unprognostic (8.27e-2)" "unprognostic (1.56e-1)" "unprognostic (5.97e-2)" "unprognostic (5.80e-2)" "unprognostic (1.85e-1)" "unprognostic (4.39e-2)" "unprognostic (8.46e-2)" PGAM2 PGAM-M ENSG00000164708 "Phosphoglycerate mutase 2" P15259 7 44062727-44065567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 1112.4;skeletal muscle: 4078.1;tongue: 1636.7" "Cell type enriched" "Detected in many" 4 "Late spermatids: 3000.2" "Cell type enriched" "Detected in many" 27 "Spermatogenic cell types: 3000.2" "Cell type enhanced" "Detected in many" "astrocyte: 17.0;ependymal cell: 15.3;upper rhombic lip: 21.0;vascular associated smooth muscle cell: 13.3" "Cancer enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "prostate cancer: 8.8;thyroid cancer: 14.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Skeletal myofibers: 1405876755.7" "Group enriched" "Detected in many" "heart muscle: 993434664.7;skeletal muscle: 1805094303.9" "HPA043801, HPA050314, HPA060173" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA 16000000 "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 45 Nucleoplasm "Nucleoli, Cytosol" "HPA043801: , HPA050314: , HPA060173: " "unprognostic (2.07e-1)" "unprognostic (8.87e-2)" "unprognostic (1.18e-1)" "unprognostic (5.17e-3)" "unprognostic (2.17e-1)" "unprognostic (1.38e-2)" "unprognostic (6.74e-2)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (4.34e-1)" "unprognostic (6.63e-2)" "unprognostic (1.62e-1)" "unprognostic (3.25e-2)" "unprognostic (4.11e-2)" "unprognostic (2.68e-2)" "unprognostic (1.59e-1)" "unprognostic (8.66e-2)" "unprognostic (1.04e-2)" "unprognostic (3.24e-2)" "unprognostic (4.19e-2)" "unprognostic (2.84e-2)" "unprognostic (3.10e-2)" "unprognostic (1.24e-1)" "unprognostic (3.58e-2)" PGAM4 "dJ1000K24.1, PGAM-B, PGAM1, PGAM3" ENSG00000226784 "Phosphoglycerate mutase family member 4" Q8N0Y7 X 77967949-77969638 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Glycolysis "Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 320 "ovary: 32029.6" "HPA042528, HPA060483" Uncertain Approved "Nucleoplasm,Mid piece" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 24: Neurons - Mixed function" "Cluster 61: BICR 18 - Protein kinases" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 21 Nucleoplasm "Mid piece" "HPA042528: , HPA060483: " "unprognostic (3.76e-2)" PGAP6 "M83, TMEM6, TMEM8, TMEM8A" ENSG00000129925 "Post-GPI attachment to proteins 6" Q9HCN3 16 370788-387113 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 114.1;Epididymal principal cells: 79.9;Esophageal apical cells: 80.0;Late spermatids: 175.3;Syncytiotrophoblasts: 77.2" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 175.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Keratinocytes: 34450.7;Large ducts: 59296.8" "Not detected" "Not detected" "HPA051281, HPA064673" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 4: Neutrophils - Degranulation" "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 54: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 10 Nucleoplasm "Cytokinetic bridge" "HPA051281: , HPA064673: " "unprognostic (1.69e-1)" "unprognostic (8.30e-2)" "unprognostic (1.27e-3)" "unprognostic (3.50e-2)" "unprognostic (1.72e-1)" "unprognostic (9.81e-2)" "unprognostic (3.50e-1)" "unprognostic (8.44e-2)" "unprognostic (2.09e-3)" "unprognostic (1.24e-2)" "unprognostic (5.21e-2)" "unprognostic (2.00e-2)" "unprognostic (3.24e-3)" "unprognostic (7.24e-2)" "unprognostic (2.96e-1)" "unprognostic (3.48e-3)" "unprognostic (2.00e-1)" "unprognostic (2.14e-1)" "unprognostic (4.79e-2)" "unprognostic (3.58e-1)" "unprognostic (1.37e-2)" "unprognostic (2.86e-2)" "unprognostic (6.58e-2)" "unprognostic (2.99e-1)" "unprognostic (5.22e-1)" "unprognostic (8.04e-3)" "unprognostic (1.28e-1)" "unprognostic (3.75e-2)" "unprognostic (1.19e-1)" PGF "D12S1900, PGFL, PIGF, PLGF, PlGF-2, SHGC-10760" ENSG00000119630 "Placental growth factor" P49763 14 74941834-74955626 "Cancer-related genes, Candidate cardiovascular disease genes, FDA approved drug targets, Plasma proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Differentiation" "Developmental protein, Growth factor, Heparin-binding, Mitogen" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 66.8" "Group enriched" "Detected in many" 7 "Extravillous trophoblasts: 2360.8;Syncytiotrophoblasts: 2809.4" "Cell type enriched" "Detected in many" 26 "Trophoblast cells: 2809.4" "Group enriched" "Detected in some" 5 "pericyte: 117.7;vascular associated smooth muscle cell: 79.9" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 138.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Sarcoma: 41.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "spinal cord: 12.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA041624 Approved Nucleoplasm,Mitochondria,Cytosol "Secreted to blood" "Growth factor" No No 20800 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 Nucleoplasm "Mitochondria, Cytosol" "HPA041624: " "unprognostic (6.22e-2)" "unprognostic (2.41e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-1)" "unprognostic (1.96e-2)" "unprognostic (9.92e-2)" "unprognostic (1.30e-2)" "unprognostic (1.70e-3)" "unprognostic (1.09e-1)" "unprognostic (3.70e-2)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (2.67e-5)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (2.14e-1)" "unprognostic (5.53e-2)" "potential prognostic unfavorable (6.21e-5)" "unprognostic (6.96e-3)" "unprognostic (5.08e-2)" "unprognostic (1.17e-1)" "unprognostic (4.30e-3)" "unprognostic (6.48e-3)" "unprognostic (1.72e-2)" "unprognostic (5.25e-3)" "unprognostic (9.52e-3)" "unprognostic (8.82e-3)" "unprognostic (1.97e-1)" "unprognostic (3.42e-3)" "unprognostic (9.40e-2)" "unprognostic (2.93e-2)" "unprognostic (4.33e-2)" PGGHG "ATHL1, FLJ22635" ENSG00000142102 "Protein-glucosylgalactosylhydroxylysine glucosidase" Q32M88 11 289126-296107 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 622.9" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 46.7;Innate lymphoid cells: 61.5;Loop of henle epithelial cells: 53.4;Neutrophils: 105.4;Pancreatic acinar cells: 90.8;Papillary tip epithelial cells: 71.7;Proximal tubule cells: 46.5;Renal collecting duct principal cells: 122.4;Tuft cells: 46.1" "Cell type enhanced" "Detected in many" "Acinar cells: 90.8;Ductal cells: 122.4;Neutrophils: 105.4" "Cell type enhanced" "Detected in some" "leukocyte: 72.3" "Cancer enhanced" "Detected in all" "Kidney Renal Papillary Cell Carcinoma (TCGA): 119.3" "Region enriched" "Detected in all" 5 "cerebral cortex: 50.9" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" "Fallopian tube cells: 29562.1;Hepatocytes: 49292.5;Macrophages: 23495.5;Pancreatic islets: 16708.6;T-cells: 36863.0" "Low tissue specificity" "Detected in many" "HPA039383, HPA058829" Uncertain Enhanced Cytosol NA Yes "Cluster 15: NK-cells - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 Cytosol "HPA039383: , HPA058829: " "unprognostic (4.87e-2)" "unprognostic (1.68e-3)" "unprognostic (5.85e-2)" "unprognostic (1.61e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (1.73e-3)" "unprognostic (2.67e-2)" "unprognostic (1.45e-2)" "potential prognostic unfavorable (9.84e-4)" "unprognostic (1.79e-1)" "potential prognostic favorable (3.22e-4)" "unprognostic (6.42e-2)" "unprognostic (6.52e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-1)" "unprognostic (3.29e-1)" "unprognostic (2.18e-1)" "unprognostic (5.51e-2)" "unprognostic (1.58e-2)" "unprognostic (1.20e-2)" "unprognostic (1.10e-1)" "unprognostic (9.32e-2)" "unprognostic (3.47e-1)" "unprognostic (1.41e-2)" "potential prognostic favorable (5.56e-4)" "unprognostic (9.75e-2)" "unprognostic (2.22e-2)" "unprognostic (1.74e-1)" PGM1 ENSG00000079739 "Phosphoglucomutase 1" P36871 1 63593411-63660245 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" Isomerase "Congenital disorder of glycosylation, Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 1460.8;tongue: 735.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 250.0;Cardiomyocytes: 203.4;Extravillous trophoblasts: 300.5;Granulosa cells: 219.0;Hepatocytes: 305.8;Myonuclei: 368.0;Pancreatic acinar cells: 203.4;Thymic myoid cells: 225.7" "Cell type enhanced" "Detected in all" "Myocytes: 368.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Hepatocytes: 754315665.9;Skeletal myofibers: 1808245568.3" "Tissue enhanced" "Detected in all" "liver: 1545832833.5" "CAB004666, HPA024190, HPA024637, HPA046329" Enhanced Supported Cytosol NA NA 20000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 15: Kidney cancer - Membrane components" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 15 Cytosol "CAB004666: , HPA024190: , HPA024637: , HPA046329: " "unprognostic (1.11e-1)" "unprognostic (2.83e-1)" "unprognostic (1.21e-1)" "potential prognostic unfavorable (3.32e-4)" "unprognostic (5.74e-3)" "unprognostic (3.37e-2)" "unprognostic (2.17e-1)" "unprognostic (1.43e-2)" "unprognostic (6.07e-2)" "unprognostic (5.71e-2)" "potential prognostic favorable (7.55e-4)" "unprognostic (1.23e-2)" "unprognostic (7.35e-2)" "unprognostic (1.61e-2)" "unprognostic (1.52e-1)" "unprognostic (3.29e-3)" "unprognostic (6.60e-3)" "unprognostic (6.64e-3)" "unprognostic (9.37e-2)" "unprognostic (2.48e-1)" "unprognostic (1.21e-1)" "unprognostic (1.62e-3)" "unprognostic (6.14e-3)" "unprognostic (1.03e-1)" "unprognostic (1.06e-1)" "unprognostic (6.87e-2)" "unprognostic (2.60e-2)" "unprognostic (2.79e-2)" "unprognostic (1.81e-1)" "unprognostic (1.49e-1)" "unprognostic (1.02e-1)" PGM2L1 "BM32A, FLJ32029" ENSG00000165434 "Phosphoglucomutase 2 like 1" Q6PCE3 11 74330316-74398433 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glucose metabolism" "Isomerase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.1" "Cell type enhanced" "Detected in many" "Gonadotrophs: 192.9;Pancreatic acinar cells: 232.9;Pituicytes/FSCs: 239.0;Respiratory ciliated cells: 157.2;Schwann cells: 236.2" "Cell type enhanced" "Detected in many" "Acinar cells: 232.9;Glial cells: 239.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 91337588.9;Microglia and Neuropil: 72873372.7;Neurons: 67168843.3" "Tissue enriched" "Detected in many" "cerebral cortex: 113603290.5" "HPA056995, HPA060948" Enhanced Approved Mitochondria No No 140000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 1 Mitochondria "HPA056995: , HPA060948: " "unprognostic (3.72e-2)" "unprognostic (1.13e-2)" "unprognostic (6.96e-2)" "unprognostic (3.21e-1)" "unprognostic (3.54e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-2)" "unprognostic (2.69e-2)" "unprognostic (3.04e-1)" "unprognostic (6.48e-3)" "unprognostic (2.30e-3)" "potential prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (1.24e-2)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (8.30e-2)" "unprognostic (3.02e-1)" "unprognostic (2.38e-2)" "unprognostic (9.46e-2)" "unprognostic (9.22e-3)" "unprognostic (6.43e-2)" "unprognostic (2.78e-1)" "unprognostic (4.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.66e-1)" "unprognostic (1.87e-1)" "unprognostic (2.48e-1)" "unprognostic (3.29e-2)" "unprognostic (2.13e-1)" PGM5 PGMRP ENSG00000154330 "Phosphoglucomutase 5" Q15124 9 68328308-68531061 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 231.1;urinary bladder: 218.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 339.9;Cardiomyocytes: 193.8;Lymphatic endothelial cells: 532.9;Microglia: 246.9;Myonuclei: 219.2;Pituitary stem cells: 145.3;Retinal bipolar cells: 243.8;Retinal pigment epithelial cells: 200.4;Smooth muscle cells: 501.8;Vascular endothelial cells: 162.0;Vascular smooth muscle cells: 140.0" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 339.9;Endothelial cells: 532.9;Smooth muscle cells: 501.8" "Group enriched" "Detected in many" 6 "central nervous system macrophage: 314.7;endothelial cell: 453.4" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 47.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 48 "neutrophil: 4.8" "Lineage enriched" "Detected in single" 48 "granulocytes: 4.8" "Cancer enhanced" "Detected in many" "Sarcoma: 8.1" "Adipose subcutaneous - Smooth muscle cells, Kidney - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 850456674.5" "Tissue enhanced" "Detected in all" "bone marrow: 394002572.3" "CAB034397, HPA046329, HPA067102" Enhanced Uncertain Cytosol NA NA 250000 "Cluster 35: Neutrophils - Protein binding" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "CAB034397: , HPA046329: , HPA067102: " "unprognostic (1.10e-2)" "unprognostic (3.46e-1)" "unprognostic (6.02e-3)" "unprognostic (1.38e-2)" "unprognostic (2.47e-2)" "unprognostic (3.02e-1)" "unprognostic (2.51e-1)" "unprognostic (1.34e-1)" "unprognostic (1.15e-1)" "unprognostic (2.88e-2)" "validated prognostic favorable (8.13e-8)" "validated prognostic favorable (1.61e-6)" "unprognostic (1.30e-1)" "validated prognostic favorable (1.57e-4)" "validated prognostic favorable (8.36e-4)" "potential prognostic favorable (7.63e-4)" "unprognostic (9.17e-3)" "unprognostic (5.52e-2)" "unprognostic (5.01e-2)" "unprognostic (7.87e-3)" "unprognostic (9.00e-2)" "unprognostic (4.76e-2)" "unprognostic (2.19e-1)" "unprognostic (2.60e-2)" "unprognostic (1.30e-2)" "unprognostic (1.05e-2)" "unprognostic (1.39e-1)" "unprognostic (5.46e-3)" "unprognostic (1.81e-1)" "unprognostic (1.93e-1)" "unprognostic (1.48e-1)" PHAF1 "C16orf6, C16orf70, FLJ12076, lin-10, LIN10" ENSG00000125149 "Phagosome assembly factor 1" Q9BSU1 16 67109941-67148544 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 54.0" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 111.8;Hepatocytes: 99.9" "Cell type enhanced" "Detected in many" "Glandular cells: 111.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 3478676.1" "Low tissue specificity" "Detected in many" "HPA041131, HPA041214" Approved Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 30: White matter - Myelination" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 51: Secretory epithelial cells - Mixed function" 13 "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA041131: , HPA041214: " "unprognostic (9.55e-2)" "unprognostic (3.79e-2)" "unprognostic (2.82e-2)" "unprognostic (9.70e-2)" "unprognostic (2.85e-1)" "unprognostic (8.30e-2)" "unprognostic (1.60e-1)" "unprognostic (3.23e-3)" "unprognostic (1.22e-1)" "unprognostic (9.53e-2)" "unprognostic (2.66e-3)" "unprognostic (1.33e-1)" "unprognostic (2.77e-2)" "unprognostic (2.61e-1)" "unprognostic (5.91e-2)" "unprognostic (1.67e-1)" "unprognostic (7.20e-3)" "unprognostic (5.33e-2)" "unprognostic (6.94e-2)" "unprognostic (4.60e-2)" "unprognostic (3.54e-2)" "unprognostic (2.91e-3)" "unprognostic (4.75e-3)" "unprognostic (9.29e-2)" "unprognostic (4.14e-1)" "unprognostic (1.37e-1)" "unprognostic (1.34e-1)" "unprognostic (1.16e-1)" "unprognostic (2.16e-1)" "unprognostic (1.04e-1)" "unprognostic (7.34e-2)" PHC3 "EDR3, FLJ12729, FLJ12967, HPH3" ENSG00000173889 "Polyhomeotic homolog 3" Q8NDX5 3 170086732-170181749 "Predicted intracellular proteins" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.0" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 498.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1514656.7" "Tissue enhanced" "Detected in many" "intestine: 3410461.4" "HPA039162, HPA062031" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 40: Non-specific - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 14 Nucleoplasm "HPA039162: , HPA062031: " "unprognostic (6.02e-2)" "unprognostic (5.48e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-2)" "unprognostic (1.53e-1)" "unprognostic (1.15e-1)" "unprognostic (2.22e-1)" "unprognostic (2.94e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (2.22e-4)" "validated prognostic favorable (6.57e-4)" "validated prognostic favorable (4.60e-5)" "unprognostic (7.08e-2)" "unprognostic (1.56e-2)" "unprognostic (1.22e-1)" "unprognostic (2.83e-1)" "unprognostic (2.40e-1)" "unprognostic (6.56e-3)" "unprognostic (8.77e-2)" "unprognostic (8.66e-2)" "potential prognostic unfavorable (9.40e-4)" "potential prognostic unfavorable (6.12e-5)" "unprognostic (3.41e-3)" "unprognostic (1.60e-2)" "unprognostic (1.74e-3)" "unprognostic (4.12e-2)" "unprognostic (1.71e-2)" "unprognostic (1.57e-1)" "unprognostic (2.01e-1)" "unprognostic (1.61e-2)" "unprognostic (3.38e-1)" PHF12 "KIAA1523, PF1" ENSG00000109118 "PHD finger protein 12" Q96QT6 17 28905250-28951771 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 343.8" "Cell type enriched" "Detected in many" 4 "Neutrophils: 343.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 40.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 40.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 830189.8;Neurons: 484875.0" "Tissue enriched" "Detected in single" 7778 "lymphoid tissue: 777807.2" "HPA021410, HPA021452" Approved Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 20 Nucleoplasm "HPA021410: , HPA021452: " "potential prognostic favorable (3.47e-4)" "unprognostic (1.04e-1)" "unprognostic (1.14e-1)" "unprognostic (3.85e-2)" "unprognostic (1.17e-1)" "unprognostic (2.69e-2)" "unprognostic (2.87e-1)" "unprognostic (5.35e-2)" "unprognostic (3.42e-2)" "unprognostic (6.22e-3)" "unprognostic (6.94e-2)" "unprognostic (9.57e-2)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "unprognostic (5.71e-2)" "unprognostic (1.76e-1)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "potential prognostic favorable (5.54e-4)" "unprognostic (2.03e-2)" "unprognostic (1.24e-1)" "unprognostic (9.27e-2)" "unprognostic (1.79e-2)" "unprognostic (2.76e-1)" "unprognostic (6.10e-3)" "unprognostic (1.27e-1)" "unprognostic (6.39e-3)" "unprognostic (7.04e-2)" "unprognostic (2.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.83e-1)" PHF21A "BHC80, BM-006, KIAA1696" ENSG00000135365 "PHD finger protein 21A" Q96BD5 11 45929319-46121454 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Neutrophils: 3250.4" "Cell type enriched" "Detected in many" 6 "Neutrophils: 3250.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2388 "Granulosa cells: 144100.5;Neurons: 333544.4" "Not detected" "Not detected" "HPA023253, HPA023580" Uncertain Supported Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 65: Brain - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 39 Nucleoplasm "HPA023253: , HPA023580: " "unprognostic (2.69e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "unprognostic (6.52e-3)" "unprognostic (8.83e-2)" "unprognostic (4.38e-2)" "unprognostic (1.97e-1)" "unprognostic (4.00e-2)" "unprognostic (1.56e-1)" "unprognostic (2.60e-2)" "unprognostic (3.08e-2)" "unprognostic (5.30e-2)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (9.31e-6)" "unprognostic (1.86e-1)" "unprognostic (2.30e-1)" "unprognostic (1.16e-3)" "unprognostic (2.53e-2)" "unprognostic (1.91e-1)" "unprognostic (2.57e-3)" "unprognostic (4.92e-2)" "unprognostic (4.05e-2)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (1.03e-1)" "unprognostic (5.64e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-2)" "unprognostic (3.33e-1)" "unprognostic (7.31e-2)" "unprognostic (8.38e-2)" PHGDH "PDG, PGDH, SERA" ENSG00000092621 "Phosphoglycerate dehydrogenase" O43175 1 119648411-119744218 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cholangiocytes: 182.6;Epididymal principal cells: 269.4;Esophageal basal cells: 209.4;Lacrimal acinar cells: 199.3;Late spermatids: 198.0;Salivary acinar cells: 140.1" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 269.4" "Cell type enhanced" "Detected in many" "astrocyte: 54.4;Bergmann glia: 61.5;oligodendrocyte: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 25.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB003681, HPA021241, HPA024031, CAB068216" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitotic spindle,Primary cilium,Cytosol" Yes No 490000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 70: Non-specific - Protein processing" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 57 "Nucleoplasm, Plasma membrane, Cytosol" "Mitotic spindle, Primary cilium" "CAB003681: , CAB068216: , HPA021241: , HPA024031: " "unprognostic (9.51e-2)" "unprognostic (2.45e-1)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (2.52e-2)" "unprognostic (8.33e-2)" "unprognostic (2.37e-2)" "unprognostic (3.19e-1)" "unprognostic (4.85e-2)" "unprognostic (1.37e-3)" "unprognostic (5.79e-2)" "unprognostic (1.12e-1)" "unprognostic (5.12e-3)" "unprognostic (3.46e-3)" "unprognostic (5.01e-2)" "unprognostic (5.73e-2)" "unprognostic (1.03e-1)" "unprognostic (5.52e-3)" "unprognostic (4.16e-2)" "unprognostic (4.73e-3)" "unprognostic (2.90e-1)" "unprognostic (1.48e-2)" "unprognostic (4.48e-3)" "unprognostic (2.59e-2)" "unprognostic (1.93e-1)" "unprognostic (8.78e-2)" "unprognostic (1.99e-1)" "unprognostic (4.31e-2)" "unprognostic (1.50e-1)" "unprognostic (2.24e-1)" "unprognostic (3.56e-1)" PHKA1 PHKA ENSG00000067177 "Phosphorylase kinase regulatory subunit alpha 1" P46020 X 72578814-72714319 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Calmodulin-binding, Muscle protein" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "parathyroid gland: 30.1;skeletal muscle: 96.1;tongue: 83.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 147.7;Astrocytes: 153.7;Choroid plexus epithelial cells: 179.1;Gonadotrophs: 97.7;Lactotrophs: 123.5;Myonuclei: 181.8;Pituicytes/FSCs: 126.5;Retinal pigment epithelial cells: 170.5;Somatotrophs: 145.6;Thyrotrophs: 206.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 147.7;Ciliated cells: 179.1;Glial cells: 153.7;Myocytes: 181.8;Pigment cells: 170.5;Pituitary endocrine cells: 206.3" "Cell type enhanced" "Detected in all" "astrocyte: 187.6;choroid plexus epithelial cell: 151.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 35199820.2" "Tissue enhanced" "Detected in many" "fallopian tube: 13854627.2;skeletal muscle: 21868514.3" "HPA001081, HPA075355" Enhanced Approved Vesicles,Cytosol NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 50: Lymphoma - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 8 "Vesicles, Cytosol" "HPA001081: , HPA075355: " "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (2.76e-1)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" "unprognostic (1.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.37e-1)" "unprognostic (6.89e-2)" "unprognostic (2.09e-2)" "unprognostic (2.76e-2)" "unprognostic (1.33e-1)" "unprognostic (2.76e-2)" "unprognostic (1.25e-1)" "unprognostic (2.47e-3)" "unprognostic (8.60e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (8.96e-2)" "unprognostic (2.42e-1)" "unprognostic (1.48e-1)" "unprognostic (2.13e-1)" "unprognostic (1.28e-1)" "unprognostic (5.19e-1)" "unprognostic (1.43e-1)" "unprognostic (3.12e-2)" "unprognostic (3.85e-1)" "unprognostic (9.81e-2)" "unprognostic (2.35e-1)" PHLPP2 "KIAA0931, PHLPPL, PPM3B" ENSG00000040199 "PH domain and leucine rich repeat protein phosphatase 2" Q6ZVD8 16 71637835-71724701 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 20.7;retina: 29.8" "Cell type enhanced" "Detected in many" "Colonocytes: 153.1;Cone photoreceptor cells: 322.9;Enterocytes: 285.5;Retinal pigment epithelial cells: 200.4;Rod photoreceptor cells: 346.7" "Cell type enhanced" "Detected in many" "Enterocytes: 285.5;Neuronal cells: 346.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 166151.4;Granulosa cells: 524591.2;Microglia and Neuropil: 257494.2;Neurons: 500901.6" "Tissue enriched" "Detected in single" 4860 "cerebral cortex: 486045.0" "HPA040761, HPA041837, HPA048598" Approved Supported "Vesicles,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Centriolar satellite,Basal body,Cytosol" Yes No "Cluster 42: Retina - Visual perception" "Cluster 1: Neurons - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 79: Photoreceptor cells - Phototransduction" 12 "Cytokinetic bridge, Mitotic spindle, Primary cilium, Cytosol" "Vesicles, Primary cilium tip, Centriolar satellite, Basal body" "HPA040761: , HPA041837: , HPA048598: " "unprognostic (3.71e-2)" "unprognostic (8.38e-2)" "unprognostic (1.55e-1)" "unprognostic (2.36e-1)" "unprognostic (6.38e-2)" "unprognostic (1.70e-1)" "unprognostic (4.61e-1)" "unprognostic (1.47e-2)" "unprognostic (2.27e-1)" "unprognostic (2.48e-2)" "unprognostic (1.51e-2)" "unprognostic (2.49e-1)" "unprognostic (9.87e-2)" "unprognostic (5.21e-2)" "unprognostic (1.05e-1)" "unprognostic (9.80e-2)" "unprognostic (6.40e-3)" "unprognostic (7.96e-2)" "unprognostic (6.89e-2)" "unprognostic (6.54e-2)" "unprognostic (7.34e-2)" "unprognostic (6.03e-3)" "unprognostic (1.24e-1)" "unprognostic (2.30e-2)" "unprognostic (2.47e-2)" "unprognostic (1.74e-1)" "unprognostic (1.78e-1)" "unprognostic (3.31e-2)" "unprognostic (9.46e-2)" "unprognostic (3.20e-3)" "unprognostic (1.97e-2)" PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase 1" Q8TCT1 17 49223366-49230787 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 90.6" "Cell type enriched" "Detected in some" 8 "Late spermatids: 2845.4" "Cell type enriched" "Detected in some" 8 "Spermatogenic cell types: 2845.4" "Cell type enhanced" "Detected in some" "lower rhombic lip: 3.2;mammillary body: 3.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 160 "eosinophil: 171.7;neutrophil: 428.7" "Lineage enriched" "Detected in many" 228 "granulocytes: 428.7" "Cancer enriched" "Detected in many" 8 "Bone cancer: 39.9" "Adipose visceral - Neutrophils, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 361 "Glomeruli: 36130.0" "Group enriched" "Detected in some" 1380 "bone marrow: 192515.2;cerebral cortex: 83394.9" HPA065025 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Actin filaments" "Plasma membrane" "HPA065025: " "unprognostic (7.60e-3)" "unprognostic (7.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.79e-1)" "unprognostic (5.19e-2)" "unprognostic (1.35e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" "unprognostic (6.76e-2)" "unprognostic (2.37e-2)" "unprognostic (2.23e-1)" "unprognostic (1.18e-1)" "unprognostic (1.57e-1)" PHOX2A "ARIX, CFEOM2, FEOM2, PMX2A" ENSG00000165462 "Paired like homeobox 2A" O14813 11 72239077-72245664 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "adrenal gland: 18.8" "Cell type enriched" "Detected in some" 6 "Adrenal medulla cells: 63.8" "Cell type enriched" "Detected in some" 6 "Adrenal endocrine cells: 63.8" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Ovary Serous Cystadenocarcinoma (TCGA): 13.6" "Region enriched" "Detected in some" 9 "pons: 38.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 755 "Neuroblastoma: 337.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053810, HPA065621, HPA078004" Enhanced Supported Nucleoplasm No NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 18: Adrenal cortex cells - Steroidogensis" 3 Nucleoplasm "HPA053810: , HPA065621: , HPA078004: " "unprognostic (1.21e-1)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" PHOX2B "NBPhox, PMX2B" ENSG00000109132 "Paired like homeobox 2B" Q99453 4 41744082-41748725 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "adrenal gland: 8.1;intestine: 2.4" "Cell type enriched" "Detected in some" 72 "Adrenal medulla cells: 95.7" "Cell type enriched" "Detected in single" 432 "Adrenal endocrine cells: 95.7" "Cell type enriched" "Detected in single" 8 "splatter: 1.6" "Not detected" "Not detected" "Group enriched" "Detected in some" 41 "medulla oblongata: 21.8;pons: 32.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 93 "Neuroblastoma: 170.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells" "Region enriched" "Detected in single" 17 "pons and medulla: 5.6" "Group enriched" "Detected in some" 27 "medulla oblongata: 2.2;pons: 3.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA074325, HPA074941" Enhanced Enhanced Nucleoplasm NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 43: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 18: Adrenal cortex cells - Steroidogensis" 1 Nucleoplasm "HPA074325: , HPA074941: " PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 652.0;Extravillous trophoblasts: 626.3;Late spermatids: 1540.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1540.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myofibers: 121349011.7" "Tissue enhanced" "Detected in all" "heart muscle: 440190461.3;skeletal muscle: 560377427.1" "CAB013584, HPA020952" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 950000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 2 Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane" "CAB013584: , HPA020952: " "unprognostic (9.09e-2)" "unprognostic (1.79e-2)" "unprognostic (2.39e-1)" "unprognostic (2.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.61e-2)" "unprognostic (2.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (1.12e-5)" "unprognostic (1.37e-3)" "unprognostic (1.29e-3)" "unprognostic (3.93e-3)" "unprognostic (4.58e-2)" "unprognostic (1.09e-2)" "unprognostic (3.53e-2)" "unprognostic (1.26e-3)" "unprognostic (4.61e-1)" "unprognostic (2.50e-1)" "unprognostic (9.09e-2)" "unprognostic (6.15e-3)" "unprognostic (3.69e-2)" "unprognostic (3.00e-2)" "unprognostic (3.14e-2)" "unprognostic (5.51e-3)" "unprognostic (1.01e-1)" "unprognostic (2.18e-2)" "unprognostic (2.27e-1)" "unprognostic (9.34e-2)" "unprognostic (4.27e-2)" PHTF1 PHTF ENSG00000116793 "Putative homeodomain transcription factor 1" Q9UMS5 1 113696831-113759489 "Plasma proteins, Predicted membrane proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 257.4;Megakaryocyte-Erythroid progenitors: 661.9;Neutrophils: 485.0" "Cell type enhanced" "Detected in all" "Megakaryocytes: 661.9;Neutrophils: 485.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA059486 Approved "Nucleoli,Nuclear bodies" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 "Nuclear bodies" Nucleoli "HPA059486: " "unprognostic (2.84e-1)" "unprognostic (2.28e-1)" "unprognostic (2.37e-1)" "unprognostic (4.58e-1)" "unprognostic (3.32e-2)" "unprognostic (1.90e-1)" "unprognostic (2.41e-1)" "unprognostic (3.62e-1)" "unprognostic (1.26e-1)" "unprognostic (1.77e-2)" "unprognostic (8.70e-3)" "unprognostic (1.77e-1)" "unprognostic (1.66e-1)" "unprognostic (5.10e-2)" "unprognostic (2.74e-2)" "unprognostic (5.22e-2)" "unprognostic (6.66e-2)" "unprognostic (6.01e-2)" "unprognostic (1.73e-1)" "unprognostic (5.68e-3)" "unprognostic (6.98e-2)" "unprognostic (2.32e-1)" "unprognostic (6.10e-2)" "unprognostic (3.72e-1)" "unprognostic (2.12e-1)" "unprognostic (2.99e-1)" "unprognostic (1.72e-2)" "unprognostic (1.80e-1)" "unprognostic (3.24e-1)" "unprognostic (1.03e-1)" "unprognostic (4.27e-2)" PHYHIP "DYRK1AP3, KIAA0273, PAHX-AP" ENSG00000168490 "Phytanoyl-CoA 2-hydroxylase interacting protein" Q92561 8 22219703-22232101 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 347.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 88.7;Brain inhibitory neurons: 62.8;Corticotrophs: 44.2;Other brain neurons: 30.8;Pituicytes/FSCs: 22.0;Podocytes: 111.8;Smooth muscle cells: 38.7" "Cell type enhanced" "Detected in many" "Neuronal cells: 88.7;Pituitary endocrine cells: 44.2;Renal nephron cells: 111.8;Smooth muscle cells: 38.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 14.1;Thyroid Carcinoma (TCGA): 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Kidney - Podocytes, Lung - Fibroblasts_2, Spleen - Fibroblasts_2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "amygdala: 133.6;basal ganglia: 395.5;cerebellum: 336.2;cerebral cortex: 333.8;hippocampal formation: 387.6" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 42314958.5;Microglia and Neuropil: 57544295.3;Neurons: 78077363.8" "Group enriched" "Detected in some" 332746 "cerebral cortex: 31576304.1;intestine: 34972993.1" "HPA068030, HPA069318" Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 10 Mitochondria Nucleoplasm "HPA068030: , HPA069318: " "unprognostic (7.78e-3)" "potential prognostic favorable (3.77e-4)" "unprognostic (1.67e-2)" "unprognostic (5.41e-2)" "unprognostic (1.37e-3)" "unprognostic (3.06e-2)" "unprognostic (7.64e-2)" "unprognostic (7.02e-3)" "unprognostic (1.51e-1)" "unprognostic (1.86e-1)" "unprognostic (3.26e-1)" "unprognostic (7.70e-2)" "potential prognostic favorable (5.18e-4)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (3.68e-5)" "unprognostic (8.87e-2)" "unprognostic (2.43e-2)" "unprognostic (1.80e-1)" PHYKPL "AGXT2L2, MGC15875" ENSG00000175309 "5-phosphohydroxy-L-lysine phospho-lyase" Q8IUZ5 5 178208471-178232802 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Hepatocytes: 28352463.4;Proximal tubules: 9200648.2" "Low tissue specificity" "Detected in all" "HPA036461, HPA063608" Approved Approved Mitochondria Yes No 120000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 8 Mitochondria "HPA036461: , HPA063608: " "unprognostic (8.70e-2)" "unprognostic (2.18e-1)" "unprognostic (4.30e-2)" "unprognostic (3.65e-2)" "unprognostic (5.47e-2)" "unprognostic (1.06e-1)" "unprognostic (4.14e-1)" "unprognostic (4.30e-2)" "unprognostic (4.68e-2)" "potential prognostic favorable (6.18e-5)" "unprognostic (1.56e-2)" "unprognostic (1.28e-2)" "unprognostic (2.52e-2)" "unprognostic (4.66e-2)" "unprognostic (5.73e-2)" "unprognostic (1.50e-2)" "unprognostic (2.60e-1)" "unprognostic (2.60e-2)" "unprognostic (7.70e-2)" "unprognostic (1.13e-1)" "unprognostic (4.10e-3)" "unprognostic (4.35e-1)" "unprognostic (2.06e-3)" "unprognostic (1.15e-1)" "unprognostic (2.13e-3)" "unprognostic (2.06e-1)" "unprognostic (3.83e-3)" "unprognostic (2.16e-1)" "unprognostic (1.48e-1)" PIAS2 "ARIP3, miz, PIASX-ALPHA, PIASX-BETA, ZMIZ4" ENSG00000078043 "Protein inhibitor of activated STAT 2" O75928 18 46803218-46920160 "Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 62.8" "Cell type enhanced" "Detected in many" "Early spermatids: 533.7;Late primary spermatocytes: 548.0;Late spermatids: 799.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 799.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1657205.6" "Not detected" "Not detected" "HPA068792, HPA077584" Enhanced Enhanced Nucleoplasm Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 67: Testis - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 13: Non-specific - Mixed function" "Cluster 24: Neutrophils - Innate immunity signal integration" 55 Nucleoplasm "HPA068792: , HPA077584: " "unprognostic (5.95e-2)" "unprognostic (3.79e-1)" "unprognostic (8.96e-2)" "unprognostic (2.04e-1)" "unprognostic (3.11e-2)" "unprognostic (4.65e-1)" "unprognostic (1.80e-1)" "unprognostic (2.62e-3)" "unprognostic (1.41e-1)" "unprognostic (1.56e-2)" "unprognostic (1.79e-2)" "potential prognostic favorable (9.48e-4)" "unprognostic (1.83e-3)" "unprognostic (1.30e-3)" "unprognostic (1.31e-2)" "unprognostic (9.87e-2)" "unprognostic (1.17e-1)" "unprognostic (4.92e-2)" "unprognostic (6.02e-3)" "unprognostic (4.61e-2)" "unprognostic (1.62e-1)" "unprognostic (1.83e-2)" "unprognostic (4.12e-2)" "unprognostic (4.11e-2)" "unprognostic (8.32e-2)" "unprognostic (1.91e-1)" "unprognostic (5.41e-2)" "unprognostic (2.43e-1)" "unprognostic (1.66e-2)" "unprognostic (8.71e-3)" "unprognostic (7.10e-2)" PIAS4 "FLJ12419, Piasg, PIASY, ZMIZ6" ENSG00000105229 "Protein inhibitor of activated STAT 4" Q8N2W9 19 4007736-4039386 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway, Wnt signaling pathway" "DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 86.0;Late primary spermatocytes: 147.2;Late spermatids: 409.2" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 409.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 826188.7;Distal tubules: 389542.9" "Tissue enriched" "Detected in single" 94 "intestine: 9395.7" "HPA010598, HPA076008" Enhanced Supported Nucleoplasm,Centrosome NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 67: Testis - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 83 Nucleoplasm Centrosome "HPA010598: , HPA076008: " "unprognostic (1.06e-1)" "unprognostic (8.98e-2)" "unprognostic (2.30e-1)" "unprognostic (5.44e-2)" "unprognostic (2.31e-1)" "unprognostic (1.25e-1)" "unprognostic (2.19e-1)" "unprognostic (4.47e-2)" "unprognostic (9.30e-3)" "unprognostic (1.13e-1)" "unprognostic (8.60e-3)" "unprognostic (4.50e-2)" "unprognostic (4.94e-1)" "unprognostic (1.87e-3)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.46e-1)" "unprognostic (2.63e-1)" "unprognostic (4.95e-2)" "unprognostic (2.68e-1)" "unprognostic (3.92e-3)" "unprognostic (4.35e-3)" "unprognostic (4.22e-2)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (2.04e-2)" "unprognostic (2.47e-1)" "unprognostic (1.70e-2)" "unprognostic (4.34e-2)" "unprognostic (3.37e-1)" "unprognostic (8.42e-3)" PIF1 "C15orf20, FLJ22692" ENSG00000140451 "PIF1 5'-to-3' DNA helicase" Q9H611 15 64815632-64825668 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-binding, Helicase, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.6" "Cell type enhanced" "Detected in many" "Early spermatids: 29.5;Enteric transient amplifying cells: 12.7;Esophageal basal cells: 12.1;Hofbauer cells: 8.8;Megakaryocyte progenitors: 13.0;Monocyte progenitors: 21.0;NK-cells: 11.2;Plasma cells: 19.9" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 21.0;Plasma cells: 19.9;Spermatogenic cell types: 29.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 19.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Mitotic cells (Minor salivary gland), Prostate - Fibroblasts, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" CAB018701 Supported Supported Nucleoplasm NA Yes "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" Nucleoplasm "CAB018701: " "unprognostic (1.15e-2)" "unprognostic (2.08e-1)" "unprognostic (3.59e-1)" "unprognostic (1.17e-1)" "unprognostic (9.62e-2)" "unprognostic (1.39e-1)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (7.44e-3)" "validated prognostic unfavorable (4.70e-4)" "validated prognostic unfavorable (4.70e-6)" "unprognostic (2.71e-3)" "potential prognostic unfavorable (5.55e-4)" "unprognostic (7.36e-2)" "unprognostic (9.38e-2)" "unprognostic (1.98e-1)" "unprognostic (1.60e-2)" "unprognostic (6.65e-2)" "potential prognostic unfavorable (8.42e-4)" "unprognostic (3.32e-2)" "potential prognostic favorable (2.61e-4)" "potential prognostic unfavorable (8.81e-4)" "unprognostic (2.71e-3)" "unprognostic (2.73e-1)" "unprognostic (3.42e-2)" PIGL ENSG00000108474 "Phosphatidylinositol glycan anchor biosynthesis class L" Q9Y2B2 17 16217191-16351797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "GPI-anchor biosynthesis, Lipid metabolism" Hydrolase "Deafness, Disease variant, Ichthyosis, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 279 "Keratinocytes: 27925.3" "Not detected" "Not detected" HPA012739 Approved Approved Nucleoplasm,Cytosol No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 2 "Nucleoplasm, Cytosol" "HPA012739: " "unprognostic (2.42e-1)" "unprognostic (1.60e-1)" "unprognostic (8.38e-2)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" "unprognostic (4.78e-3)" "unprognostic (2.31e-2)" "unprognostic (7.93e-3)" "unprognostic (8.79e-2)" "unprognostic (1.18e-2)" "unprognostic (9.46e-3)" "unprognostic (3.37e-2)" "unprognostic (5.95e-2)" "unprognostic (5.23e-2)" "unprognostic (1.48e-1)" "unprognostic (1.50e-1)" "unprognostic (3.26e-1)" "unprognostic (1.40e-1)" "unprognostic (1.70e-1)" "unprognostic (1.80e-2)" "unprognostic (1.07e-1)" "unprognostic (1.55e-2)" "unprognostic (4.10e-3)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (7.99e-3)" "unprognostic (1.33e-1)" "unprognostic (2.58e-3)" "unprognostic (7.30e-2)" "unprognostic (1.26e-1)" "unprognostic (3.16e-1)" "unprognostic (6.39e-2)" PIGP "DCRC, DSCR5, DSRC" ENSG00000185808 "Phosphatidylinositol glycan anchor biosynthesis class P" P57054 21 37062846-37073170 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 416.1;Epididymal principal cells: 307.9;Gastric chief cells: 191.1;Oocytes: 188.8;Parietal cells: 224.5" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 307.9;Spermatogenic cell types: 416.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA026921 Uncertain Approved Vesicles Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 3: Early primary spermatocytes - Early meiosis" 21 Vesicles "HPA026921: " "unprognostic (1.56e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (9.54e-3)" "unprognostic (5.20e-2)" "unprognostic (3.55e-1)" "unprognostic (6.19e-2)" "unprognostic (5.82e-3)" "unprognostic (9.72e-2)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (2.95e-1)" "potential prognostic favorable (3.09e-5)" "unprognostic (4.76e-2)" "unprognostic (9.85e-2)" "unprognostic (8.50e-2)" "unprognostic (2.90e-1)" "unprognostic (1.55e-2)" "unprognostic (1.86e-1)" "unprognostic (2.86e-2)" "unprognostic (5.14e-2)" "unprognostic (1.42e-1)" "unprognostic (5.87e-2)" "unprognostic (3.84e-3)" "unprognostic (9.60e-2)" "unprognostic (6.89e-2)" "unprognostic (1.22e-3)" "unprognostic (1.96e-1)" "unprognostic (1.49e-1)" "unprognostic (2.56e-2)" "unprognostic (8.52e-2)" "unprognostic (2.14e-1)" "unprognostic (2.63e-1)" PIGW "FLJ37433, Gwt1" ENSG00000277161 "Phosphatidylinositol glycan anchor biosynthesis class W" Q7Z7B1 17 36534987-36539310 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Acyltransferase, Transferase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 2.1;Bergmann glia: 2.8;Brain excitatory neurons: 2.8;Brain inhibitory neurons: 3.2;Choroid plexus epithelial cells: 2.3;Distal convoluted tubule cells: 2.0;Ependymal cells: 3.3;Loop of henle epithelial cells: 2.0;Microglia: 2.4;Oligodendrocyte progenitor cells: 3.3;Oligodendrocytes: 3.4;Other brain neurons: 4.3;Papillary tip epithelial cells: 2.2;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 2.2" "Cell type enhanced" "Detected in some" "Ciliated cells: 3.3;Ductal cells: 2.2;Glial cells: 3.4;Neuronal cells: 4.3;Renal nephron cells: 2.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Hepatocytes: 367092.2;Large ducts: 498921.8" "Not detected" "Not detected" HPA023499 Approved "Plasma membrane" No Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "Plasma membrane" "HPA023499: " "unprognostic (1.00e-1)" "unprognostic (1.22e-2)" "unprognostic (2.75e-1)" "unprognostic (3.30e-1)" "unprognostic (1.20e-1)" "unprognostic (8.54e-2)" "unprognostic (1.37e-2)" "unprognostic (8.69e-2)" "unprognostic (4.06e-2)" "potential prognostic favorable (6.47e-4)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (9.51e-2)" "unprognostic (2.91e-2)" "unprognostic (2.79e-2)" "potential prognostic favorable (5.33e-4)" "unprognostic (2.85e-1)" "unprognostic (1.00e-1)" "unprognostic (2.97e-1)" "unprognostic (2.85e-3)" "unprognostic (1.09e-2)" "unprognostic (2.66e-1)" "unprognostic (9.56e-2)" "unprognostic (5.17e-2)" "unprognostic (1.58e-3)" "unprognostic (1.08e-1)" PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 77.8;lymphoid tissue: 58.6;salivary gland: 69.4" "Cell type enhanced" "Detected in many" "B-cells: 201.3;Kupffer cells: 353.6;Lacrimal acinar cells: 154.9;Macrophages: 228.3;Microglia: 242.8;Monocyte progenitors: 154.6;monocytes: 481.9;Neutrophil progenitors: 347.0;Neutrophils: 962.8;NK-cells: 178.2;pDCs: 182.8;Salivary acinar cells: 174.3" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 481.9;Neutrophils: 962.8" "Group enriched" "Detected in many" 12 "central nervous system macrophage: 313.6;leukocyte: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.6;memory B-cell: 48.4;naive B-cell: 44.6;non-classical monocyte: 123.7" "Group enriched" "Detected in all" 6 "B-cells: 48.4;monocytes: 123.7" "Cancer enhanced" "Detected in many" "Leukemia: 54.3;lymphoma: 97.4" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Ductal cells, Skeletal muscle - Macrophages, Spleen - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 20284904.0;Hepatocytes: 10868526.4" "Tissue enhanced" "Detected in many" "lymphoid tissue: 20318428.9" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 40: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 9 "Nucleoplasm, Cytosol" "Plasma membrane" "CAB026136: , HPA038452: " "unprognostic (6.24e-2)" "unprognostic (2.15e-1)" "unprognostic (3.45e-1)" "unprognostic (3.98e-3)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (3.22e-2)" "unprognostic (1.02e-1)" "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (1.51e-2)" "unprognostic (1.47e-1)" "unprognostic (3.36e-3)" "unprognostic (7.50e-2)" "unprognostic (1.16e-2)" "unprognostic (1.97e-1)" "unprognostic (1.95e-1)" "unprognostic (1.25e-1)" "unprognostic (1.76e-1)" "unprognostic (7.42e-2)" "unprognostic (9.52e-2)" "unprognostic (1.16e-1)" "unprognostic (5.70e-3)" "unprognostic (2.69e-2)" "unprognostic (3.15e-1)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (1.35e-1)" "unprognostic (4.42e-1)" PIK3C2A PI3K-C2alpha ENSG00000011405 "Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha" O00443 11 17077730-17207986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Exocytosis, Lipid metabolism" "Kinase, Transferase" "Cataract, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 967.2;Sertoli cells: 550.5;Syncytiotrophoblasts: 729.7" "Cell type enhanced" "Detected in many" "Glial cells: 967.2;Trophoblast cells: 729.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 1081.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "pancreas: 4955668.8" "HPA037641, HPA037642" Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 54: Immune cells - T cell receptor" "Cluster 24: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 49 Nucleoplasm "Vesicles, Cytosol" "HPA037641: , HPA037642: " "unprognostic (9.45e-3)" "unprognostic (6.76e-2)" "unprognostic (1.81e-1)" "unprognostic (3.48e-2)" "unprognostic (1.09e-1)" "unprognostic (1.35e-2)" "unprognostic (1.02e-1)" "unprognostic (5.35e-3)" "unprognostic (1.40e-1)" "unprognostic (6.46e-3)" "validated prognostic favorable (3.04e-7)" "validated prognostic favorable (5.71e-4)" "unprognostic (1.25e-1)" "unprognostic (3.44e-2)" "unprognostic (9.75e-2)" "unprognostic (2.22e-1)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (3.37e-1)" "unprognostic (7.42e-2)" "potential prognostic unfavorable (4.53e-5)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (6.06e-4)" "unprognostic (2.30e-1)" "unprognostic (4.45e-3)" "unprognostic (4.16e-1)" "unprognostic (5.70e-2)" "unprognostic (4.78e-2)" "unprognostic (2.24e-1)" "unprognostic (6.41e-2)" "unprognostic (3.25e-1)" PIK3CA PI3K ENSG00000121879 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha" P42336 3 179148114-179240093 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Lipid metabolism, Phagocytosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 384.7" "Cell type enhanced" "Detected in many" "Neutrophils: 384.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "blood vessel: 701267.1" "HPA009985, CAB017804" Approved Approved "Microtubules,Primary cilium,Mitochondria,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 45 "Primary cilium, Cytosol" "Microtubules, Mitochondria" "CAB017804: , HPA009985: " "unprognostic (2.75e-1)" "unprognostic (2.49e-2)" "unprognostic (9.47e-2)" "unprognostic (1.90e-1)" "unprognostic (3.80e-2)" "unprognostic (2.08e-2)" "unprognostic (2.58e-2)" "unprognostic (1.19e-2)" "unprognostic (2.17e-1)" "unprognostic (2.38e-2)" "potential prognostic favorable (2.60e-6)" "unprognostic (1.26e-3)" "unprognostic (3.71e-2)" "unprognostic (2.60e-2)" "unprognostic (3.56e-1)" "unprognostic (3.58e-3)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.17e-2)" "unprognostic (1.95e-3)" "unprognostic (2.39e-3)" "unprognostic (7.49e-2)" "unprognostic (6.69e-2)" "unprognostic (5.37e-2)" "unprognostic (9.64e-2)" "unprognostic (4.05e-2)" "unprognostic (8.15e-2)" "unprognostic (2.79e-1)" "unprognostic (1.11e-1)" "unprognostic (1.03e-1)" PIK3CB PIK3C1 ENSG00000051382 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta" P42338 3 138652698-138834928 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Autophagy, Cell adhesion, Endocytosis, Lipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 574.8;Neutrophils: 499.6;Platelets: 498.6" "Cell type enhanced" "Detected in all" "Neutrophils: 574.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lung: 3551441.7" "CAB031938, HPA042288, HPA064207" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Midbody Yes No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 23 "Nucleoplasm, Nucleoli" "Vesicles, Midbody" "CAB031938: , HPA042288: , HPA064207: " "unprognostic (2.53e-1)" "unprognostic (5.78e-3)" "unprognostic (1.10e-1)" "unprognostic (4.76e-3)" "unprognostic (9.74e-2)" "unprognostic (9.96e-2)" "unprognostic (1.75e-1)" "unprognostic (1.45e-1)" "unprognostic (1.21e-1)" "unprognostic (1.80e-2)" "validated prognostic favorable (4.34e-7)" "validated prognostic favorable (8.48e-4)" "unprognostic (1.26e-1)" "unprognostic (1.26e-1)" "unprognostic (7.55e-2)" "unprognostic (2.22e-2)" "unprognostic (1.62e-2)" "unprognostic (4.33e-2)" "unprognostic (2.32e-2)" "unprognostic (1.82e-1)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (1.64e-4)" "unprognostic (8.43e-3)" "unprognostic (3.11e-1)" "unprognostic (5.33e-3)" "unprognostic (1.22e-1)" "unprognostic (3.59e-1)" "unprognostic (1.53e-1)" "unprognostic (6.67e-2)" "unprognostic (7.90e-2)" "unprognostic (2.32e-1)" PIK3CD p110D ENSG00000171608 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta" O00329 1 9629889-9729114 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Adaptive immunity, Chemotaxis, Differentiation, Immunity, Inflammatory response, Innate immunity, Lipid metabolism" "Kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 44.2;lymphoid tissue: 44.5" "Cell type enhanced" "Detected in many" "B-cells: 117.5;Hematopoietic stem cells: 112.1;Innate lymphoid cells: 124.8;Kupffer cells: 163.0;Microglia: 153.2;Monocyte progenitors: 191.4;Neutrophil progenitors: 340.8;Neutrophils: 828.0;NK-cells: 159.4;pDCs: 245.3;T-cells: 132.6" "Cell type enhanced" "Detected in many" "dendritic cells: 245.3;Neutrophils: 828.0" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 185.3;leukocyte: 245.1;pericyte: 237.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 57.4;lymphoma: 54.3" "Adrenal gland - Macrophages, Breast - T-cells, Testis - Spermatogonia, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 5450082.4;Macrophages: 6789303.9;Oocytes: 4225182.5;T-cells: 15933279.5" "Group enriched" "Detected in many" "bone marrow: 10639633.4;intestine: 12362406.8;lymphoid tissue: 27970163.7" "CAB015420, HPA044953" Enhanced Approved "Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Cytosol" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 18: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 Vesicles "Microtubules, Cytokinetic bridge, Primary cilium, Primary cilium tip, Cytosol" "CAB015420: , HPA044953: " "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.12e-2)" "unprognostic (8.58e-2)" "unprognostic (1.70e-1)" "unprognostic (8.43e-2)" "unprognostic (6.33e-2)" "unprognostic (7.70e-2)" "unprognostic (7.00e-2)" "unprognostic (1.43e-1)" "unprognostic (2.50e-1)" "unprognostic (1.30e-1)" "potential prognostic favorable (5.14e-5)" "unprognostic (2.86e-1)" "unprognostic (1.11e-1)" "unprognostic (1.63e-3)" "unprognostic (1.99e-2)" "unprognostic (8.44e-3)" "unprognostic (1.97e-1)" "unprognostic (7.88e-3)" "unprognostic (1.18e-1)" "unprognostic (5.07e-2)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (4.25e-2)" "unprognostic (1.75e-1)" "unprognostic (3.37e-2)" "unprognostic (1.40e-2)" "unprognostic (1.43e-1)" "unprognostic (1.43e-1)" "unprognostic (1.86e-1)" "unprognostic (4.74e-1)" PIK3R1 "GRB1, p85, p85-ALPHA" ENSG00000145675 "Phosphoinositide-3-kinase regulatory subunit 1" P27986 5 68215740-68301821 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Protein transport, Stress response, Transport" "GTPase activation" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 628.4;Oligodendrocyte progenitor cells: 578.8;Schwann cells: 570.8;Thymic myoid cells: 775.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 33402220.2" "Tissue enhanced" "Detected in all" "lymphoid tissue: 20651843.3" "HPA001216, CAB004268" Approved Approved Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 190 Cytosol "CAB004268: , HPA001216: " "unprognostic (5.44e-3)" "unprognostic (4.41e-2)" "unprognostic (2.62e-1)" "unprognostic (7.67e-2)" "unprognostic (1.39e-1)" "unprognostic (2.04e-1)" "unprognostic (2.37e-1)" "unprognostic (3.12e-2)" "unprognostic (1.06e-2)" "unprognostic (7.24e-3)" "potential prognostic favorable (5.75e-6)" "unprognostic (2.46e-3)" "unprognostic (1.16e-1)" "unprognostic (7.80e-3)" "potential prognostic favorable (2.14e-4)" "potential prognostic favorable (2.08e-4)" "unprognostic (5.59e-2)" "unprognostic (1.59e-1)" "unprognostic (1.35e-1)" "unprognostic (2.26e-1)" "unprognostic (6.40e-3)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (3.27e-1)" "unprognostic (1.58e-1)" "unprognostic (6.19e-2)" "unprognostic (1.49e-1)" "unprognostic (3.76e-3)" "unprognostic (1.29e-1)" "unprognostic (8.97e-2)" "unprognostic (7.94e-2)" PIK3R4 "p150, VPS15" ENSG00000196455 "Phosphoinositide-3-kinase regulatory subunit 4" Q99570 3 130678934-130746829 "Enzymes, Essential proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA036032, HPA036033" Approved Approved "Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Basal body" Yes NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 47 "Vesicles, Microtubules, Primary cilium" "Cytokinetic bridge, Basal body" "HPA036032: , HPA036033: " "unprognostic (3.24e-1)" "unprognostic (3.24e-2)" "unprognostic (2.16e-1)" "unprognostic (6.57e-3)" "unprognostic (1.36e-1)" "unprognostic (1.83e-1)" "unprognostic (2.60e-1)" "unprognostic (2.11e-1)" "unprognostic (3.08e-2)" "unprognostic (1.68e-2)" "potential prognostic favorable (1.29e-7)" "unprognostic (2.64e-2)" "unprognostic (9.68e-2)" "unprognostic (1.57e-1)" "unprognostic (1.73e-1)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (2.62e-1)" "unprognostic (2.53e-1)" "unprognostic (1.67e-3)" "unprognostic (3.91e-1)" "unprognostic (1.63e-3)" "unprognostic (1.64e-2)" "unprognostic (1.51e-1)" "unprognostic (1.18e-2)" "unprognostic (8.88e-3)" "unprognostic (7.16e-2)" "unprognostic (1.46e-1)" "unprognostic (1.72e-1)" "unprognostic (8.77e-2)" "unprognostic (1.97e-1)" PIK3R5 "p101, P101-PI3K" ENSG00000141506 "Phosphoinositide-3-kinase regulatory subunit 5" Q8WYR1 17 8878911-8965712 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 84.2" "Cell type enhanced" "Detected in many" "cDC: 375.3;Kupffer cells: 320.8;Macrophages: 460.4;Microglia: 333.5;monocytes: 812.2;Neutrophil progenitors: 279.0;Neutrophils: 2074.7;NK-cells: 383.0;pDCs: 357.6;T-cells: 266.1" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 812.2;Neutrophils: 2074.7" "Group enriched" "Detected in some" 96 "central nervous system macrophage: 431.0;leukocyte: 339.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Leukemia: 11.8;lymphoma: 6.1" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "T-cells: 795264.0" "Tissue enriched" "Detected in single" 773 "lymphoid tissue: 77261.5" "HPA044505, HPA052247, HPA052412" Uncertain Supported "Centriolar satellite,Cytosol" No NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 59: Leukemia - T-cell receptor" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Cytosol "Centriolar satellite" "HPA044505: , HPA052247: , HPA052412: " "unprognostic (3.90e-1)" "unprognostic (9.69e-2)" "unprognostic (3.44e-3)" "unprognostic (6.89e-3)" "unprognostic (1.78e-1)" "unprognostic (5.64e-2)" "unprognostic (1.54e-1)" "unprognostic (2.37e-1)" "unprognostic (8.40e-3)" "unprognostic (5.35e-2)" "unprognostic (1.79e-2)" "unprognostic (4.60e-1)" "unprognostic (1.15e-2)" "unprognostic (1.17e-2)" "unprognostic (1.02e-2)" "unprognostic (1.17e-1)" "unprognostic (5.57e-2)" "unprognostic (1.33e-1)" "unprognostic (2.79e-2)" "unprognostic (1.96e-1)" "unprognostic (1.26e-1)" "unprognostic (7.76e-2)" "unprognostic (1.17e-1)" "unprognostic (1.20e-2)" "unprognostic (1.66e-3)" "unprognostic (1.03e-1)" "unprognostic (3.47e-2)" "unprognostic (1.55e-2)" "unprognostic (6.14e-2)" "unprognostic (1.07e-1)" PIM2 ENSG00000102096 "Pim-2 proto-oncogene, serine/threonine kinase" Q9P1W9 X 48913182-48919024 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 96.5;intestine: 82.3;lymphoid tissue: 152.7" "Cell type enriched" "Detected in many" 5 "Plasma cells: 420.8" "Cell type enriched" "Detected in many" 5 "Plasma cells: 420.8" "Cell type enhanced" "Detected in many" "leukocyte: 16.1" "Cancer enriched" "Detected in all" 7 "Testicular Germ Cell Tumor (TCGA): 384.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Myeloma: 827.3" "Adipose visceral - Plasma cells, Adrenal gland - Plasma cells, Breast - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Stomach - Plasma cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 159 "Proximal tubules: 15912.8" "Not detected" "Not detected" HPA000285 Approved Cytosol NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 29: Forebrain - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 5 Cytosol "HPA000285: " "unprognostic (1.59e-3)" "unprognostic (3.50e-3)" "unprognostic (2.98e-1)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (2.60e-1)" "unprognostic (1.91e-3)" "unprognostic (1.02e-2)" "unprognostic (3.29e-3)" "unprognostic (4.43e-3)" "potential prognostic unfavorable (1.51e-5)" "unprognostic (7.69e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (9.32e-2)" "unprognostic (5.17e-2)" "unprognostic (1.30e-2)" "unprognostic (3.65e-2)" "unprognostic (4.92e-2)" "unprognostic (1.43e-1)" "unprognostic (1.01e-1)" "unprognostic (5.00e-3)" "unprognostic (2.06e-2)" "unprognostic (1.96e-1)" "unprognostic (7.94e-2)" "unprognostic (7.53e-2)" "unprognostic (1.10e-2)" "unprognostic (1.53e-2)" "unprognostic (2.23e-1)" "unprognostic (2.45e-1)" "unprognostic (5.24e-2)" "unprognostic (1.18e-1)" PIM3 ENSG00000198355 "Pim-3 proto-oncogene, serine/threonine kinase" Q86V86 22 49960768-49964072 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 317.7;Extravillous trophoblasts: 461.2;Prostatic club cells: 352.4;Syncytiotrophoblasts: 458.3" "Cell type enhanced" "Detected in all" "Trophoblast cells: 461.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 20.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Neutrophils" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA068758 Supported Cytosol NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 1 Cytosol "HPA068758: " "unprognostic (1.06e-1)" "unprognostic (7.39e-2)" "unprognostic (8.11e-2)" "unprognostic (1.51e-2)" "unprognostic (3.29e-2)" "unprognostic (4.78e-2)" "unprognostic (1.56e-2)" "unprognostic (5.80e-2)" "unprognostic (9.04e-2)" "unprognostic (3.06e-2)" "unprognostic (3.78e-1)" "unprognostic (5.62e-2)" "unprognostic (3.05e-2)" "unprognostic (1.75e-2)" "unprognostic (2.28e-1)" "unprognostic (9.93e-3)" "unprognostic (1.89e-1)" "unprognostic (2.03e-1)" "unprognostic (3.07e-2)" "potential prognostic unfavorable (5.70e-4)" "unprognostic (8.65e-2)" "unprognostic (2.33e-2)" "unprognostic (1.03e-2)" "unprognostic (3.15e-1)" "unprognostic (4.24e-2)" "unprognostic (2.24e-2)" "unprognostic (4.54e-2)" "unprognostic (3.51e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (5.39e-2)" PIMREG "CATS, FAM64A, FLJ10156, FLJ10491, RCS1" ENSG00000129195 "PICALM interacting mitotic regulator" Q9BSJ6 17 6444441-6451469 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0" "Cell type enhanced" "Detected in some" "Enteric stem cells: 6.0;Enteric transient amplifying cells: 18.9;Epicardial cells: 6.8;Esophageal basal cells: 9.9;Gastric progenitor cells: 15.4;Granulosa cells: 12.2;Hofbauer cells: 15.2;Megakaryocyte progenitors: 12.8;Megakaryocytes: 6.2;Monocyte progenitors: 21.6;Neuroendocrine cells: 6.2;Paneth cells: 11.6" "Cell type enhanced" "Detected in many" "Megakaryocytes: 12.8;Mononuclear phagocytes: 21.6;Proliferating cells: 18.9;Reproductive supporting cells: 12.2;Secretory gland support: 11.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Region enhanced" "Detected in many" "white matter: 5.7" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043783, HPA049934" Uncertain Enhanced Nucleoplasm Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 2: Neurons - Nucleosome" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 20 Nucleoplasm "HPA043783: , HPA049934: " "unprognostic (8.36e-2)" "unprognostic (2.88e-2)" "unprognostic (7.76e-2)" "unprognostic (2.40e-1)" "unprognostic (4.39e-2)" "unprognostic (1.59e-1)" "unprognostic (2.97e-2)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (4.30e-6)" "validated prognostic unfavorable (1.57e-9)" "validated prognostic unfavorable (1.73e-4)" "potential prognostic unfavorable (6.70e-6)" "unprognostic (2.62e-2)" "potential prognostic unfavorable (7.49e-5)" "unprognostic (4.11e-3)" "unprognostic (3.46e-2)" "unprognostic (3.87e-2)" "unprognostic (3.47e-2)" "unprognostic (1.72e-1)" "unprognostic (2.55e-3)" "unprognostic (4.63e-2)" "unprognostic (6.91e-2)" "unprognostic (1.88e-1)" "unprognostic (6.06e-2)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (2.93e-1)" "unprognostic (8.64e-2)" PIN4 "EPVH, PAR14, PAR17" ENSG00000102309 "Peptidylprolyl cis/trans isomerase, NIMA-interacting 4" Q9Y237 X 72181353-72302926 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 292.9;Mesothelial cells: 310.5;Thymocytes: 421.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA054483, HPA064504" Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 44: Plasma cells - Antibody production & secretion" 13 "Nucleoplasm, Nucleoli" "Mitotic chromosome" "HPA054483: , HPA064504: " "unprognostic (2.62e-1)" "unprognostic (4.46e-2)" "unprognostic (2.39e-1)" "unprognostic (1.53e-2)" "unprognostic (9.33e-2)" "unprognostic (1.53e-1)" "unprognostic (6.52e-2)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (2.64e-4)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (8.09e-2)" "unprognostic (9.61e-2)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (8.65e-4)" "unprognostic (2.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.57e-1)" "unprognostic (2.15e-3)" "unprognostic (1.75e-2)" "unprognostic (9.69e-3)" "unprognostic (2.79e-1)" "unprognostic (2.13e-1)" "unprognostic (2.03e-1)" "unprognostic (1.84e-1)" "unprognostic (3.26e-1)" "unprognostic (1.71e-1)" "unprognostic (1.21e-1)" "unprognostic (3.48e-1)" "unprognostic (7.73e-3)" "unprognostic (9.31e-2)" "unprognostic (1.62e-1)" PINLYP ENSG00000234465 "Phospholipase A2 inhibitor and LY6/PLAUR domain containing" A6NC86 19 43575801-43583964 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 33.2;Leydig cells: 26.9;Ovarian stromal cells: 27.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 21.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 20.8" "Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA061218 Uncertain Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Centrosome,Basal body" "Secreted to blood" "No annotated function" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" "Vesicles, Microtubules, Primary cilium" "Cytokinetic bridge, Mitotic spindle, Centrosome, Basal body" "HPA061218: " "unprognostic (7.50e-2)" "unprognostic (1.06e-1)" "unprognostic (6.37e-2)" "unprognostic (3.43e-2)" "unprognostic (2.24e-1)" "unprognostic (1.86e-3)" "potential prognostic unfavorable (2.45e-6)" "unprognostic (5.67e-2)" "unprognostic (8.26e-2)" "unprognostic (2.55e-2)" "unprognostic (3.35e-2)" "unprognostic (7.19e-2)" "unprognostic (9.68e-2)" "potential prognostic favorable (6.89e-4)" "unprognostic (3.48e-3)" "unprognostic (5.56e-2)" "unprognostic (3.07e-2)" "unprognostic (1.65e-1)" "unprognostic (7.20e-2)" "unprognostic (1.06e-1)" "unprognostic (2.00e-1)" "unprognostic (1.29e-2)" "unprognostic (2.04e-1)" "unprognostic (2.36e-2)" "unprognostic (1.66e-1)" "unprognostic (3.47e-3)" "unprognostic (2.19e-1)" "unprognostic (2.48e-2)" "unprognostic (1.74e-1)" PIP5K1C "KIAA0589, LCCS3, PIP5Kgamma" ENSG00000186111 "Phosphatidylinositol-4-phosphate 5-kinase type 1 gamma" O60331 19 3630183-3700468 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell adhesion, Chemotaxis, Endocytosis, Exocytosis, Lipid metabolism, Phagocytosis" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 116.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Lung - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 23371522.6;Cardiomyocytes: 6113502.8;Microglia and Neuropil: 23947018.1;Neurons: 11209633.9" "Group enriched" "Detected in many" "cerebral cortex: 34089467.2;intestine: 11157896.6" HPA017168 Approved Supported Nucleoplasm,Cytosol No No "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 13 Nucleoplasm Cytosol "HPA017168: " "potential prognostic favorable (5.65e-4)" "unprognostic (1.24e-1)" "unprognostic (1.27e-2)" "unprognostic (1.65e-1)" "unprognostic (4.68e-2)" "unprognostic (1.14e-3)" "unprognostic (1.36e-1)" "unprognostic (1.17e-1)" "unprognostic (1.22e-2)" "unprognostic (1.78e-1)" "unprognostic (3.95e-3)" "unprognostic (2.47e-2)" "unprognostic (1.24e-1)" "unprognostic (5.58e-3)" "unprognostic (5.52e-2)" "unprognostic (1.59e-1)" "unprognostic (1.93e-1)" "unprognostic (5.30e-2)" "unprognostic (2.83e-2)" "unprognostic (1.78e-3)" "unprognostic (2.63e-1)" "unprognostic (6.17e-3)" "unprognostic (6.36e-2)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-1)" "unprognostic (6.51e-2)" "unprognostic (5.24e-2)" "unprognostic (8.23e-3)" PITX1 "BFT, POTX, PTX1" ENSG00000069011 "Paired like homeodomain 1" P78337 5 135027734-135034813 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 701.1;vagina: 194.5" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 313.2;Esophageal apical cells: 3695.3;Esophageal basal cells: 919.0;Esophageal suprabasal cells: 1804.8;Suprabasal keratinocytes: 838.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 3695.3;Basal cells: 919.0;Suprabasal cells: 1804.8" "Cell type enriched" "Detected in single" 43 "choroid plexus epithelial cell: 8.2" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 163.5" "Region enriched" "Detected in all" 4 "choroid plexus: 9.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 136.9" "Minor Salivary Gland - Minor salivary gland basal cells, Stomach - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 1490 "Large ducts: 148950.8" "Not detected" "Not detected" HPA008743 Approved Supported Nucleoli Yes No "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 70 Nucleoli "HPA008743: " "unprognostic (4.51e-2)" "unprognostic (8.87e-2)" "unprognostic (1.79e-1)" "unprognostic (3.25e-1)" "unprognostic (4.22e-2)" "unprognostic (6.03e-2)" "unprognostic (4.09e-2)" "unprognostic (3.13e-2)" "unprognostic (7.76e-3)" "unprognostic (3.70e-3)" "potential prognostic unfavorable (3.22e-15)" "unprognostic (5.50e-3)" "unprognostic (4.26e-3)" "unprognostic (6.14e-3)" "unprognostic (4.54e-2)" "unprognostic (1.68e-3)" "unprognostic (3.49e-2)" "unprognostic (3.05e-2)" "unprognostic (7.30e-2)" "unprognostic (8.64e-2)" "unprognostic (1.72e-1)" "unprognostic (6.81e-3)" "unprognostic (2.58e-1)" "unprognostic (2.35e-1)" "unprognostic (3.13e-2)" "unprognostic (3.96e-2)" "unprognostic (7.00e-2)" "unprognostic (9.49e-2)" "unprognostic (3.04e-2)" "unprognostic (3.60e-2)" PITX2 "ARP1, Brx1, IGDS, IHG2, IRID2, Otlx2, RGS, RIEG, RIEG1, RS" ENSG00000164093 "Paired like homeodomain 2" Q99697 4 110617423-110642123 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Disease variant, Peters anomaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 39.5;skeletal muscle: 40.4;tongue: 26.2;urinary bladder: 26.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 40.2;Enterocytes: 42.4;Epididymal efferent duct absorptive cells: 37.3;Fibroblasts: 53.2;Gonadotrophs: 90.1;Myonuclei: 34.7;Myosatellite cells: 54.2;Paneth cells: 27.1;Pituitary stem cells: 52.1;Smooth muscle cells: 27.6;Suprabasal keratinocytes: 48.3;Thymic myoid cells: 93.8;Thyrotrophs: 65.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 53.2;Pituitary endocrine cells: 90.1;Stem cells: 54.2;Stromal cells: 93.8" "Cell type enriched" "Detected in some" 28 "mammillary body: 75.2" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "hypothalamus: 29.9;thalamus: 10.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 23 "hypothalamus: 8.6;midbrain: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA050074, HPA062728" Enhanced "Nucleoplasm,Primary cilium tip" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 4 Nucleoplasm "Primary cilium tip" "HPA050074: , HPA062728: " "unprognostic (2.26e-2)" "unprognostic (1.79e-1)" "unprognostic (2.80e-2)" "unprognostic (3.42e-1)" "unprognostic (3.07e-1)" "unprognostic (9.42e-2)" "unprognostic (2.91e-3)" "potential prognostic unfavorable (9.96e-5)" "unprognostic (6.27e-3)" "potential prognostic unfavorable (4.07e-7)" "unprognostic (4.27e-2)" "unprognostic (4.00e-2)" "unprognostic (2.11e-1)" "unprognostic (1.21e-1)" "unprognostic (3.64e-3)" "unprognostic (8.82e-2)" "unprognostic (4.92e-3)" "unprognostic (2.19e-2)" "unprognostic (2.19e-1)" "unprognostic (1.47e-1)" PJA2 "KIAA0438, Neurodap1, PRAJA2, RNF131" ENSG00000198961 "Praja ring finger ubiquitin ligase 2" O43164 5 109334713-109409974 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 726.3" "Cell type enhanced" "Detected in all" "Neutrophils: 726.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1700996.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 342674.5" "HPA039602, HPA040347" Supported Supported "Microtubules,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA No "Cluster 35: Neutrophils - Protein binding" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 16 "Microtubules, Basal body, Cytosol" "Primary cilium, Primary cilium transition zone" "HPA039602: , HPA040347: " "unprognostic (1.33e-2)" "unprognostic (8.69e-2)" "unprognostic (4.18e-1)" "unprognostic (3.78e-2)" "unprognostic (1.96e-1)" "unprognostic (4.25e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (3.03e-2)" "unprognostic (2.32e-3)" "validated prognostic favorable (1.54e-7)" "validated prognostic favorable (4.22e-4)" "unprognostic (1.53e-1)" "unprognostic (3.90e-1)" "unprognostic (5.72e-2)" "unprognostic (2.55e-1)" "unprognostic (4.57e-1)" "unprognostic (3.72e-2)" "unprognostic (4.55e-3)" "unprognostic (3.36e-3)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (3.14e-1)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (1.50e-1)" "unprognostic (7.02e-2)" "unprognostic (2.53e-1)" "unprognostic (4.05e-3)" "unprognostic (2.14e-1)" "unprognostic (4.62e-2)" "unprognostic (3.61e-1)" PKIG ENSG00000168734 "CAMP-dependent protein kinase inhibitor gamma" Q9Y2B9 20 44531785-44624247 "Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 366.9;Megakaryocyte-Erythroid progenitors: 400.4;Smooth muscle cells: 334.8" "Cell type enhanced" "Detected in all" "Megakaryocytes: 400.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "memory B-cell: 371.9;naive B-cell: 378.7" "Lineage enriched" "Detected in all" 11 "B-cells: 378.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Capillaries: 532551.8" "Tissue enhanced" "Detected in many" "heart muscle: 13780139.4" "HPA042703, HPA063690" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 18: Non-specific - Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane" "HPA042703: , HPA063690: " "unprognostic (7.22e-3)" "unprognostic (2.55e-1)" "unprognostic (3.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.89e-1)" "unprognostic (5.21e-2)" "unprognostic (7.30e-2)" "unprognostic (3.81e-1)" "unprognostic (5.89e-2)" "unprognostic (8.69e-2)" "validated prognostic favorable (6.07e-6)" "validated prognostic favorable (1.21e-4)" "potential prognostic favorable (2.69e-4)" "unprognostic (4.38e-3)" "unprognostic (5.40e-2)" "unprognostic (1.56e-2)" "unprognostic (1.94e-1)" "unprognostic (1.02e-3)" "unprognostic (1.55e-1)" "unprognostic (1.43e-1)" "unprognostic (5.04e-3)" "unprognostic (1.40e-3)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (2.89e-1)" "unprognostic (1.27e-2)" "unprognostic (2.06e-1)" "unprognostic (5.25e-3)" "unprognostic (2.25e-1)" "unprognostic (2.16e-1)" "unprognostic (4.03e-2)" PKLR ENSG00000143627 "Pyruvate kinase L/R" P30613 1 155289293-155301438 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis "Allosteric enzyme, Kinase, Transferase" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 18.4;kidney: 23.5;liver: 86.5" "Group enriched" "Detected in some" 5 "Erythrocyte progenitors: 8.9;Late spermatids: 7.0;Proximal tubule cells: 11.3" "Group enriched" "Detected in some" 6 "Erythrocytes: 8.9;Renal nephron cells: 11.3;Spermatogenic cell types: 7.0" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 7 "Liver Hepatocellular Carcinoma (TCGA): 70.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 7.2;skin cancer: 2.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Late spermatids" "Region enhanced" "Detected in single" "basal ganglia: 1.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Glomeruli: 174957257.2;Hepatocytes: 460492121.2;Proximal tubules: 228043257.3" "Tissue enriched" "Detected in many" "liver: 542422717.4" "HPA006653, CAB034376, CAB034378" Enhanced Approved Cytosol No NA 8800000 "Cluster 16: Liver & Kidney - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 2 Cytosol "CAB034376: , CAB034378: , HPA006653: " "unprognostic (1.96e-1)" "potential prognostic favorable (7.04e-7)" "unprognostic (7.94e-3)" "unprognostic (2.73e-3)" "unprognostic (5.53e-2)" "unprognostic (2.20e-2)" "unprognostic (2.82e-2)" "unprognostic (2.30e-1)" "unprognostic (2.04e-1)" "unprognostic (1.14e-1)" PKM "OIP3, PK3, PKM2, THBP1" ENSG00000067225 "Pyruvate kinase M1/2" P14618 15 72199029-72231819 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Translation regulation" "Allosteric enzyme, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 3777.5;tongue: 2492.1" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1306.9;Esophageal basal cells: 1726.6;Esophageal suprabasal cells: 1757.1;Extravillous trophoblasts: 1864.4;Late spermatids: 3109.8;Platelets: 1678.6" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 3109.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Skeletal myocytes, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 4200744607.8" "Low tissue specificity" "Detected in all" "CAB019421, HPA029501" Uncertain Enhanced "Vesicles,Cytosol,Principal piece" No No 260000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 82 Cytosol "Vesicles, Principal piece" "CAB019421: , HPA029501: " "unprognostic (2.42e-2)" "unprognostic (1.27e-2)" "unprognostic (1.64e-2)" "unprognostic (9.33e-2)" "unprognostic (2.65e-2)" "unprognostic (8.85e-3)" "unprognostic (3.85e-2)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.14e-2)" "unprognostic (2.51e-2)" "unprognostic (1.17e-1)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (7.67e-6)" "validated prognostic unfavorable (3.97e-6)" "validated prognostic unfavorable (1.98e-6)" "unprognostic (1.33e-1)" "unprognostic (1.85e-2)" "unprognostic (3.64e-2)" "unprognostic (3.64e-1)" "potential prognostic unfavorable (1.28e-4)" "unprognostic (1.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.07e-1)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (4.06e-2)" "unprognostic (2.30e-1)" "unprognostic (3.18e-1)" "unprognostic (1.40e-3)" PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in all" "bone marrow: 18520730.6;lymphoid tissue: 21950586.0;skeletal muscle: 6542707.6" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 89 "Plasma membrane" "Cytokinetic bridge" "CAB010278: , HPA003982: " "unprognostic (4.50e-2)" "unprognostic (1.65e-1)" "unprognostic (2.68e-1)" "unprognostic (2.07e-1)" "unprognostic (9.61e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (6.56e-2)" "unprognostic (4.24e-1)" "unprognostic (1.65e-2)" "potential prognostic favorable (7.65e-4)" "unprognostic (3.79e-1)" "unprognostic (2.14e-1)" "unprognostic (1.01e-2)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (4.76e-2)" "unprognostic (1.36e-1)" "unprognostic (2.15e-1)" "unprognostic (2.58e-1)" "unprognostic (1.01e-2)" "unprognostic (1.25e-2)" "unprognostic (3.15e-2)" "unprognostic (5.45e-2)" "unprognostic (5.65e-2)" "unprognostic (1.22e-1)" "unprognostic (8.86e-3)" "unprognostic (1.56e-1)" "unprognostic (6.17e-2)" "unprognostic (1.40e-1)" "unprognostic (8.50e-2)" "unprognostic (1.15e-1)" PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 827.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 80.7" "Lineage enriched" "Detected in all" 8 "granulocytes: 80.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 41 "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: , HPA057913: " "unprognostic (1.10e-1)" "unprognostic (1.56e-1)" "unprognostic (2.23e-2)" "unprognostic (3.71e-2)" "unprognostic (3.50e-3)" "unprognostic (3.51e-2)" "unprognostic (4.49e-2)" "unprognostic (2.46e-1)" "unprognostic (2.27e-2)" "potential prognostic unfavorable (2.46e-4)" "validated prognostic favorable (1.43e-5)" "validated prognostic favorable (8.91e-5)" "unprognostic (3.46e-2)" "unprognostic (1.37e-3)" "unprognostic (1.55e-1)" "unprognostic (2.23e-2)" "unprognostic (3.38e-2)" "unprognostic (3.06e-1)" "unprognostic (2.23e-2)" "unprognostic (3.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.85e-3)" "unprognostic (1.56e-2)" "unprognostic (2.18e-1)" "unprognostic (1.31e-2)" "unprognostic (4.42e-2)" "unprognostic (1.00e-1)" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (3.62e-2)" "unprognostic (7.91e-3)" PKNOX2 ENSG00000165495 "PBX/knotted 1 homeobox 2" Q96KN3 11 125164687-125433389 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 33.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 356.9;Lactotrophs: 175.6;Melanocytes: 181.5;Myonuclei: 127.6;Myosatellite cells: 175.2;Oligodendrocyte progenitor cells: 135.4;Peritubular myoid cells: 109.5;Pituitary stem cells: 111.1;Prostatic glandular cells: 127.9;Retinal pigment epithelial cells: 225.9;Thymic myoid cells: 225.7;Thyrotrophs: 182.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 356.9;Pigment cells: 225.9;Stromal cells: 225.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 26.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bone cancer: 5.5;Sarcoma: 10.0;skin cancer: 11.0;testis cancer: 5.6" "Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 269993.5" "Group enriched" "Detected in some" 77 "cerebral cortex: 7638.4;ovary: 7857.3" "HPA028867, CAB034342, HPA055368, HPA066962" Supported Enhanced "Nucleoplasm,Cytokinetic bridge" Yes NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 32 Nucleoplasm "Cytokinetic bridge" "CAB034342: , HPA028867: , HPA055368: , HPA066962: " "unprognostic (6.00e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-2)" "unprognostic (2.22e-3)" "unprognostic (7.34e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (2.37e-1)" "unprognostic (8.94e-2)" "unprognostic (5.58e-2)" "unprognostic (8.99e-2)" "unprognostic (3.66e-2)" "unprognostic (2.14e-1)" "unprognostic (5.96e-2)" "unprognostic (1.40e-1)" "unprognostic (8.88e-3)" "unprognostic (1.95e-1)" PLA2G4A "cPLA2-alpha, PLA2G4" ENSG00000116711 "Phospholipase A2 group IVA" P47712 1 186828949-186988981 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Glycerol metabolism, Leukotriene biosynthesis, Lipid biosynthesis, Lipid degradation, Lipid metabolism, Phospholipid degradation, Phospholipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 82.0;seminal vesicle: 45.5" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 135.3;Microglia: 306.8;Neutrophil progenitors: 270.1;Urothelial cells: 228.8" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 228.8;Glial cells: 306.8;Neutrophils: 270.1" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 388.1;endothelial cell: 394.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 6.8;eosinophil: 7.9;intermediate monocyte: 8.4;myeloid DC: 7.7;non-classical monocyte: 4.0;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 7 "dendritic cells: 7.7;granulocytes: 7.9;monocytes: 8.4" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts, Kidney - Fibroblasts, Pituitary gland - Fibroblasts, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 11218493.3" "Low tissue specificity" "Detected in many" "CAB010050, HPA050062, HPA054206" Approved Supported Vesicles,Cytosol NA NA 29000 "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 20 Cytosol Vesicles "CAB010050: , HPA050062: , HPA054206: " "unprognostic (2.55e-1)" "unprognostic (2.10e-3)" "unprognostic (4.15e-1)" "unprognostic (2.07e-1)" "unprognostic (9.48e-2)" "unprognostic (1.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.68e-1)" "unprognostic (2.23e-3)" "unprognostic (7.24e-2)" "potential prognostic favorable (8.47e-4)" "unprognostic (1.38e-1)" "unprognostic (1.42e-1)" "unprognostic (4.72e-2)" "unprognostic (4.73e-2)" "unprognostic (7.33e-2)" "unprognostic (2.14e-1)" "unprognostic (7.06e-2)" "unprognostic (1.31e-2)" "unprognostic (7.00e-2)" "unprognostic (2.77e-1)" "unprognostic (4.34e-3)" "unprognostic (2.29e-1)" "unprognostic (5.80e-2)" "unprognostic (8.62e-2)" "unprognostic (1.85e-1)" "unprognostic (7.62e-2)" "unprognostic (3.45e-2)" "unprognostic (7.07e-2)" "potential prognostic favorable (8.08e-4)" PLA2G4D cPLA2delta ENSG00000159337 "Phospholipase A2 group IVD" Q86XP0 15 42067009-42094562 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "cervix: 14.6;prostate: 17.9;skin 1: 13.6;vagina: 18.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Epicardial cells: 4.5;Epididymal basal cells: 2.5;Esophageal apical cells: 11.0;Foveolar cells: 2.3;Prostatic glandular cells: 7.0;Retinal horizontal cells: 2.0;Somatotrophs: 4.4;Suprabasal keratinocytes: 11.0;Thyrotrophs: 3.6" "Cell type enhanced" "Detected in some" "Apical squamous epithelial cells: 11.0;Barrier epithelial cells: 4.5;Glandular cells: 7.0;Pituitary endocrine cells: 4.4;Suprabasal cells: 11.0" "Cell type enhanced" "Detected in some" "hippocampal CA1-3: 2.7" "Group enriched" "Detected in some" 4 "Bladder Urothelial Carcinoma (TCGA): 1.7;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.8;Head and Neck Squamous Cell Carcinoma (TCGA): 2.8;Prostate Adenocarcinoma (TCGA): 2.2;Skin Cutaneous Melanoma (TCGA): 3.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Stomach - Gastric mucous cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4337 "Keratinocytes: 433663.4" "Tissue enriched" "Detected in some" "intestine: 2030388.4" HPA074206 Approved "Plasma membrane,Cytosol" NA NA "Cluster 58: Skin - Keratinization" "Cluster 29: Forebrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Cytosol "Plasma membrane" "HPA074206: " "unprognostic (2.20e-1)" "unprognostic (1.28e-1)" "unprognostic (2.56e-3)" "unprognostic (9.02e-2)" "unprognostic (2.14e-1)" "unprognostic (1.75e-1)" "unprognostic (2.00e-1)" PLAAT1 "A-C1, H-REV107, HRASLS, HRASLS1, PLA/AT1, PLAAT-1" ENSG00000127252 "Phospholipase A and acyltransferase 1" Q9HDD0 3 193241128-193277738 "Enzymes, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "skeletal muscle: 84.4;testis: 77.8;tongue: 41.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 140.8;Early spermatids: 534.6;Late primary spermatocytes: 688.7;Late spermatids: 174.4;Myonuclei: 78.9;Oligodendrocyte progenitor cells: 177.0;Platelets: 147.6" "Cell type enhanced" "Detected in many" "Glial cells: 177.0;Neuronal cells: 140.8;Platelets: 147.6;Spermatogenic cell types: 688.7" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 229.6;oligodendrocyte precursor cell: 195.6" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 19.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Skeletal myocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA051179 Uncertain Approved "Focal adhesion sites,Cytosol" No No "Cluster 4: Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 11: Neuronal - Sensory perception" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 "Focal adhesion sites" Cytosol "HPA051179: " "unprognostic (6.54e-3)" "unprognostic (9.41e-3)" "unprognostic (1.18e-2)" "unprognostic (1.93e-1)" "unprognostic (4.93e-3)" "unprognostic (1.21e-1)" "unprognostic (3.85e-1)" "unprognostic (1.42e-2)" "unprognostic (2.87e-2)" "unprognostic (3.02e-1)" "unprognostic (4.86e-2)" "potential prognostic favorable (3.81e-4)" "unprognostic (4.30e-2)" "unprognostic (2.86e-1)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.73e-4)" "unprognostic (5.16e-2)" "unprognostic (7.00e-3)" "unprognostic (2.01e-3)" "unprognostic (6.60e-3)" PLAC8 "C15, onzin" ENSG00000145287 "Placenta associated 8" Q9NZF1 4 83090048-83137075 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 345.6;intestine: 221.2;lymphoid tissue: 149.0" "Cell type enhanced" "Detected in many" "Colonocytes: 1933.5;Enterocytes: 527.7;Esophageal apical cells: 2723.8;Extravillous trophoblasts: 968.2;Foveolar cells: 726.0;Kupffer cells: 694.9;Monocyte progenitors: 404.8;Neutrophil progenitors: 486.0;pDCs: 850.8;Respiratory ciliated cells: 591.7;Respiratory deuterosomal cells: 524.5;Respiratory secretory cells: 735.6" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 2723.8;Enterocytes: 1933.5;Trophoblast cells: 968.2" "Cell type enriched" "Detected in many" 12 "leukocyte: 141.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 2328.2" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Adrenocortical cancer: 300.0" "Adipose subcutaneous - T-cells, Colon - Colon enterocytes, Prostate - T-cells, Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040465, HPA077912" Enhanced Approved Cytosol NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Cytosol "HPA040465: , HPA077912: " "unprognostic (1.83e-2)" "potential prognostic favorable (4.48e-5)" "unprognostic (1.52e-2)" "unprognostic (1.25e-2)" "unprognostic (1.62e-2)" "unprognostic (3.96e-2)" "unprognostic (2.03e-1)" "unprognostic (1.50e-2)" "unprognostic (2.73e-2)" "unprognostic (6.18e-2)" "unprognostic (2.56e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-2)" "unprognostic (1.70e-1)" "unprognostic (5.67e-2)" "unprognostic (4.28e-2)" "unprognostic (5.71e-2)" "unprognostic (1.09e-2)" "unprognostic (1.33e-2)" "unprognostic (1.30e-1)" "unprognostic (2.38e-3)" "unprognostic (4.09e-3)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (9.46e-2)" "unprognostic (9.63e-2)" "unprognostic (2.46e-1)" "unprognostic (6.88e-2)" "unprognostic (6.55e-3)" "unprognostic (5.74e-2)" "unprognostic (5.85e-2)" PLAGL1 "LOT1, ZAC" ENSG00000118495 "PLAG1 like zinc finger 1" Q9UM63 6 143940300-144064599 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 232.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 548.6;Corticotrophs: 480.4;Fibro-adipogenic progenitors: 464.3;Leydig cells: 378.5;Somatotrophs: 1408.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 548.6;Pituitary endocrine cells: 1408.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Rhabdoid: 70.2" "Adipose subcutaneous - Adipose progenitor cells, Pituitary gland - Somatotropes, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA055706 Supported "Nuclear bodies,Golgi apparatus,Vesicles" No No "Cluster 7: Non-specific - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 10 "Nuclear bodies" "Golgi apparatus, Vesicles" "HPA055706: " "unprognostic (2.94e-1)" "unprognostic (4.93e-3)" "unprognostic (7.52e-3)" "unprognostic (5.20e-3)" "unprognostic (2.45e-1)" "unprognostic (9.23e-3)" "unprognostic (5.43e-2)" "unprognostic (2.06e-1)" "unprognostic (2.96e-1)" "unprognostic (2.88e-2)" "unprognostic (1.43e-1)" "unprognostic (7.77e-2)" "unprognostic (2.32e-2)" "unprognostic (3.67e-2)" "unprognostic (2.99e-2)" "unprognostic (2.64e-1)" "unprognostic (6.93e-2)" "unprognostic (6.00e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (2.51e-1)" "unprognostic (4.02e-3)" "unprognostic (3.61e-2)" "unprognostic (8.11e-2)" "unprognostic (8.43e-3)" "unprognostic (5.47e-2)" "unprognostic (1.72e-1)" "unprognostic (1.24e-3)" "unprognostic (5.34e-2)" "potential prognostic unfavorable (8.94e-4)" "unprognostic (1.04e-3)" PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 49.6;lymphoid tissue: 38.4" "Cell type enhanced" "Detected in many" "cDC: 57.5;Hofbauer cells: 46.5;Kupffer cells: 56.4;Macrophages: 45.3;Megakaryocytes: 49.5;Microglia: 109.5;Monocyte progenitors: 41.2;monocytes: 60.9;Neutrophil progenitors: 42.1;Neutrophils: 84.4;Tuft cells: 172.9" "Cell type enhanced" "Detected in many" "dendritic cells: 57.5;Glial cells: 109.5;Mononuclear phagocytes: 60.9;Neutrophils: 84.4;Secretory gland support: 172.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 125.3;leukocyte: 47.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 5 "Leukemia: 35.8" "Adrenal gland - Macrophages, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - Kupffer cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Alveolar cell types: 1057921.6;B-cells: 1933067.0;Macrophages: 3634917.9;Neutrophils: 2014989.3;T-cells: 3526385.4" "Tissue enhanced" "Detected in many" "cerebral cortex: 18269136.7" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Golgi apparatus,Plasma membrane,Basal body,Cytosol" NA NA 18000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 Cytosol "Golgi apparatus, Plasma membrane, Basal body" "CAB009443: , HPA041298: , HPA068595: , HPA069308: " "unprognostic (5.65e-2)" "unprognostic (1.79e-1)" "unprognostic (1.56e-2)" "unprognostic (6.58e-2)" "unprognostic (2.57e-1)" "unprognostic (3.38e-2)" "unprognostic (3.74e-1)" "unprognostic (1.99e-2)" "unprognostic (5.03e-3)" "unprognostic (2.37e-1)" "unprognostic (8.80e-2)" "unprognostic (4.01e-1)" "unprognostic (2.08e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.62e-4)" "unprognostic (1.04e-1)" "unprognostic (1.48e-1)" "unprognostic (3.54e-1)" "unprognostic (1.10e-1)" "unprognostic (7.61e-2)" "unprognostic (8.68e-2)" "unprognostic (1.36e-2)" "unprognostic (2.17e-1)" "unprognostic (7.52e-3)" "unprognostic (2.46e-1)" "unprognostic (2.49e-1)" "unprognostic (8.40e-2)" "unprognostic (3.36e-2)" "unprognostic (3.06e-1)" "unprognostic (1.29e-1)" PLCD4 ENSG00000115556 "Phospholipase C delta 4" Q9BRC7 2 218607855-218637184 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 153.9;skeletal muscle: 106.9" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 296.0;Myonuclei: 370.6;Retinal bipolar cells: 300.4;Rod photoreceptor cells: 311.7" "Group enriched" "Detected in many" 5 "Myocytes: 370.6;Neuronal cells: 311.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 3.8;Rhabdoid: 5.0" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Skeletal myofibers: 88391450.0" "Tissue enriched" "Detected in some" "skeletal muscle: 4099684.7" "CAB009914, HPA038139, HPA038140" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Cytosol "Endoplasmic reticulum, Plasma membrane" "CAB009914: , HPA038139: , HPA038140: " "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (9.74e-4)" "unprognostic (2.52e-1)" "unprognostic (7.82e-3)" "unprognostic (1.46e-1)" "unprognostic (3.52e-2)" "unprognostic (4.41e-2)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (8.65e-4)" PLCG1 "NCKAP3, PLC-II, PLC1, PLC148, PLCgamma1" ENSG00000124181 "Phospholipase C gamma 1" P19174 20 41136960-41196801 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Host-virus interaction, Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 94.6;Bergmann glia: 87.7;Cardiomyocytes: 117.3;Epicardial cells: 261.5" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 261.5;Myocytes: 117.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "gdT-cell: 4.7;MAIT T-cell: 6.4;memory CD4 T-cell: 4.1;memory CD8 T-cell: 3.9;naive CD4 T-cell: 4.3;naive CD8 T-cell: 4.3;NK-cell: 3.4;T-reg: 3.8" "Group enriched" "Detected in many" 9 "NK-cells: 3.4;T-cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 16233795.2" "Low tissue specificity" "Detected in many" "CAB004277, HPA036681, HPA036682" Approved Supported "Plasma membrane,Basal body,Cytosol" NA NA 10000 "Cluster 1: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 85 "Plasma membrane" "Basal body, Cytosol" "CAB004277: , HPA036681: , HPA036682: " "unprognostic (1.77e-3)" "unprognostic (3.60e-2)" "unprognostic (8.47e-2)" "unprognostic (7.77e-3)" "unprognostic (1.45e-1)" "unprognostic (3.03e-1)" "unprognostic (8.87e-2)" "unprognostic (2.11e-1)" "unprognostic (4.87e-2)" "unprognostic (3.66e-3)" "unprognostic (1.72e-2)" "unprognostic (9.73e-2)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (7.29e-2)" "unprognostic (6.43e-3)" "unprognostic (2.14e-2)" "unprognostic (1.05e-1)" "unprognostic (1.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.99e-1)" "unprognostic (1.43e-3)" "unprognostic (5.79e-3)" "unprognostic (3.41e-1)" "unprognostic (3.67e-2)" "unprognostic (6.36e-3)" "unprognostic (6.26e-3)" "unprognostic (2.24e-1)" "unprognostic (4.43e-1)" "unprognostic (6.01e-2)" "unprognostic (2.42e-1)" PLCG2 ENSG00000197943 "Phospholipase C gamma 2" P16885 16 81779279-81962685 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 42.3" "Cell type enhanced" "Detected in many" "B-cells: 96.3;Distal convoluted tubule cells: 218.4;Loop of henle epithelial cells: 91.7;Microglia: 346.3;Podocytes: 539.4;Proximal tubule cells: 100.6;Renal collecting duct intercalated cells: 1099.2;Renal collecting duct principal cells: 149.9;Renal connecting tubule cells: 195.3;Tuft cells: 115.3" "Group enriched" "Detected in many" 5 "Ductal cells: 1099.2;Glial cells: 346.3;Renal nephron cells: 539.4" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 427.3;endothelial cell: 158.6;leukocyte: 164.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 246.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 7 "Leukemia: 28.1;lymphoma: 88.4;Myeloma: 29.1" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Kidney - Intercalated cells, Prostate - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 76211331.7" "Tissue enriched" "Detected in many" "lymphoid tissue: 120264057.5" "CAB004280, HPA020099, HPA020100" Enhanced Approved Nucleoplasm,Vesicles,Cytosol NA NA 20000 "Cluster 14: Non-specific - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 27 "Vesicles, Cytosol" Nucleoplasm "CAB004280: , HPA020099: , HPA020100: " "unprognostic (2.29e-1)" "unprognostic (6.83e-2)" "unprognostic (1.04e-2)" "unprognostic (6.26e-2)" "unprognostic (2.34e-1)" "unprognostic (1.90e-3)" "unprognostic (7.51e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (7.20e-4)" "unprognostic (8.47e-2)" "potential prognostic favorable (9.03e-9)" "unprognostic (2.83e-3)" "potential prognostic unfavorable (4.92e-4)" "unprognostic (1.18e-1)" "potential prognostic favorable (3.98e-4)" "unprognostic (7.59e-3)" "unprognostic (7.38e-2)" "unprognostic (1.99e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-1)" "unprognostic (1.28e-1)" "unprognostic (2.92e-2)" "unprognostic (3.55e-3)" "unprognostic (9.65e-2)" "unprognostic (1.72e-1)" "unprognostic (4.34e-2)" "unprognostic (1.21e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-2)" "unprognostic (1.49e-1)" "unprognostic (6.89e-2)" PLCXD3 ENSG00000182836 "Phosphatidylinositol specific phospholipase C X domain containing 3" Q63HM9 5 41306952-41510628 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.6;heart muscle: 31.0;ovary: 26.4" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 319.1;Brain excitatory neurons: 161.7;Brain inhibitory neurons: 151.0;Cardiomyocytes: 694.2;Endometrial stromal cells: 266.1;Lactotrophs: 447.5;Neuroendocrine cells: 179.6;Ovarian stromal cells: 302.8;Pancreatic islet cells: 325.5;Pituitary stem cells: 191.2;Somatotrophs: 393.4;Thyrotrophs: 239.3;Vascular endothelial cells: 148.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 319.1;Myocytes: 694.2;Pancreatic islet cells: 325.5;Pituitary endocrine cells: 447.5;Stromal cells: 302.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Kidney Chromophobe (TCGA): 8.1;Pancreatic Adenocarcinoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.5" "Adrenal gland - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 9056983.1;Pancreatic islets: 5747227.4" "Group enriched" "Detected in many" "cerebral cortex: 9828845.4;heart muscle: 5972357.3;ovary: 2922655.7" HPA046849 Uncertain Approved "Golgi apparatus" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 "Golgi apparatus" "HPA046849: " "unprognostic (1.76e-1)" "unprognostic (1.23e-2)" "unprognostic (5.43e-2)" "unprognostic (3.11e-3)" "unprognostic (7.14e-2)" "unprognostic (1.89e-2)" "unprognostic (1.53e-1)" PLD5 FLJ40773 ENSG00000180287 "Phospholipase D family member 5" Q8N7P1 1 242082986-242524697 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "blood vessel: 10.5;brain: 7.0;choroid plexus: 26.1" "Group enriched" "Detected in many" 6 "Choroid plexus epithelial cells: 2655.7;Gonadotrophs: 697.7;Retinal pigment epithelial cells: 1956.7" "Group enriched" "Detected in many" 6 "Ciliated cells: 2655.7;Pigment cells: 1956.7;Pituitary endocrine cells: 697.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 2105.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.5;Lung Adenocarcinoma (TCGA): 1.6" "Group enriched" "Detected in all" 9 "cerebellum: 34.9;choroid plexus: 117.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 5.9;Neuroblastoma: 4.9" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA028389 Approved Mitochondria No No "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 5: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 5 Mitochondria "HPA028389: " "unprognostic (3.87e-1)" "unprognostic (1.54e-2)" "unprognostic (4.01e-2)" "unprognostic (2.48e-1)" PLEKHA4 PEPP1 ENSG00000105559 "Pleckstrin homology domain containing A4" Q9H4M7 19 48837092-48868617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 104.3;Epididymal clear cells: 61.2;Leydig cells: 65.9;Ovarian stromal cells: 65.7;Pituitary stem cells: 59.3;Salivary myoepithelial cells: 63.0;Schwann cells: 134.1" "Cell type enhanced" "Detected in many" "Basal cells: 104.3;Glial cells: 134.1" "Cell type enhanced" "Detected in many" "ependymal cell: 16.9;fibroblast: 16.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 35.4" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Minor Salivary Gland - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in some" "Region enriched" "Detected in all" 6 "spinal cord: 59.6" "Cell type enriched" "Detected in some" "Oocytes: 347861.4" "Tissue enriched" "Detected in single" 2112 "lymphoid tissue: 211182.8" "HPA042978, HPA048473" Uncertain Approved "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 5 "Plasma membrane, Cytosol" "Cytokinetic bridge, Centriolar satellite" "HPA042978: , HPA048473: " "unprognostic (7.09e-2)" "potential prognostic favorable (2.77e-4)" "unprognostic (5.65e-3)" "unprognostic (9.35e-2)" "unprognostic (7.55e-2)" "unprognostic (3.55e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (9.90e-2)" "unprognostic (1.12e-1)" "unprognostic (4.35e-1)" "unprognostic (1.82e-1)" "unprognostic (1.38e-3)" "potential prognostic unfavorable (5.83e-4)" "unprognostic (1.45e-1)" "unprognostic (2.32e-1)" "unprognostic (6.28e-3)" "unprognostic (5.94e-2)" "unprognostic (1.38e-1)" "unprognostic (1.73e-2)" "unprognostic (1.60e-1)" "unprognostic (2.69e-2)" "unprognostic (1.35e-1)" "unprognostic (4.47e-1)" "unprognostic (1.34e-1)" "potential prognostic favorable (1.49e-4)" "unprognostic (3.85e-2)" "unprognostic (1.58e-1)" "unprognostic (4.85e-2)" "unprognostic (8.12e-3)" "unprognostic (7.01e-2)" PLEKHA6 "KIAA0969, PEPP3" ENSG00000143850 "Pleckstrin homology domain containing A6" Q9Y2H5 1 204218853-204377665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 280.9;Proximal tubule cells: 565.1;Retinal amacrine cells: 272.4" "Cell type enhanced" "Detected in many" "Renal nephron cells: 565.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Fibroblasts, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 32688029.4" "Tissue enhanced" "Detected in many" "Stomach: 15415102.9" "HPA028152, HPA028157, HPA054311" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 "Cell Junctions" Vesicles "HPA028152: , HPA028157: , HPA054311: " "unprognostic (1.10e-1)" "unprognostic (7.70e-2)" "unprognostic (1.46e-1)" "unprognostic (2.50e-2)" "potential prognostic favorable (5.29e-4)" "unprognostic (2.02e-1)" "unprognostic (5.47e-2)" "unprognostic (1.27e-1)" "unprognostic (2.77e-1)" "unprognostic (1.13e-1)" "potential prognostic favorable (7.70e-6)" "unprognostic (1.98e-1)" "unprognostic (1.37e-1)" "unprognostic (1.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.43e-3)" "unprognostic (4.17e-3)" "potential prognostic unfavorable (2.50e-5)" "unprognostic (5.33e-2)" "unprognostic (2.31e-1)" "unprognostic (1.41e-1)" "unprognostic (1.91e-1)" "unprognostic (2.81e-1)" "unprognostic (1.64e-1)" "unprognostic (7.77e-2)" "unprognostic (4.43e-2)" "unprognostic (1.09e-1)" "unprognostic (1.93e-2)" "unprognostic (5.18e-2)" "unprognostic (1.74e-1)" "unprognostic (3.09e-2)" PLEKHA8 "FAPP2, MGC3358" ENSG00000106086 "Pleckstrin homology domain containing A8" Q96JA3 7 30027404-30130483 "Predicted intracellular proteins" "Lipid transport, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Renal collecting duct intercalated cells: 111.9" "Cell type enhanced" "Detected in many" "Ductal cells: 111.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Oocytes: 25075.8;Skeletal myofibers: 81876.2" "Tissue enriched" "Detected in single" 3575 "lung: 357511.5" HPA072314 Uncertain "Nucleoplasm,Golgi apparatus" NA NA "Cluster 42: Retina - Visual perception" "Cluster 31: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 1 "Golgi apparatus" Nucleoplasm "HPA072314: " "unprognostic (2.85e-1)" "unprognostic (1.03e-3)" "unprognostic (1.34e-1)" "unprognostic (1.41e-2)" "unprognostic (3.98e-1)" "unprognostic (3.26e-1)" "unprognostic (4.20e-1)" "unprognostic (1.66e-1)" "unprognostic (9.23e-2)" "unprognostic (3.04e-1)" "unprognostic (1.84e-3)" "unprognostic (1.78e-2)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (4.48e-4)" "unprognostic (2.53e-1)" "unprognostic (1.06e-1)" "unprognostic (3.91e-2)" "unprognostic (2.37e-1)" "unprognostic (1.22e-2)" "unprognostic (5.19e-2)" "unprognostic (2.02e-2)" "unprognostic (2.13e-2)" "potential prognostic unfavorable (2.34e-4)" "unprognostic (1.53e-1)" "unprognostic (3.74e-2)" "unprognostic (6.46e-2)" "unprognostic (8.39e-2)" "unprognostic (8.12e-2)" "unprognostic (2.53e-1)" "unprognostic (1.67e-3)" "unprognostic (2.24e-1)" PLEKHG1 "ARHGEF41, KIAA1209" ENSG00000120278 "Pleckstrin homology and RhoGEF domain containing G1" Q9ULL1 6 150599883-150843665 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 27.0" "Cell type enhanced" "Detected in many" "B-cells: 503.6;Lymphatic endothelial cells: 541.3;Pituicytes/FSCs: 362.2;Podocytes: 302.0;Sertoli cells: 508.3;Vascular endothelial cells: 740.3" "Cell type enhanced" "Detected in many" "B-cells: 503.6;Endothelial cells: 740.3;Reproductive supporting cells: 508.3" "Cell type enhanced" "Detected in all" "endothelial cell: 640.9;fibroblast: 371.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "memory B-cell: 22.9;naive B-cell: 21.7" "Lineage enriched" "Detected in single" 31 "B-cells: 22.9" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Sertoli cells" "Region enhanced" "Detected in all" "thalamus: 51.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6868 "B-cells: 470405.7;Fallopian tube cells: 756191.0;Oocytes: 833676.6" "Tissue enriched" "Detected in single" 15935 "lymphoid tissue: 1593542.9" "HPA027128, HPA027319, HPA028270" Approved Enhanced Nucleoplasm Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 Nucleoplasm "HPA027128: , HPA027319: , HPA028270: " "unprognostic (9.12e-3)" "unprognostic (4.12e-2)" "unprognostic (8.13e-2)" "unprognostic (1.84e-1)" "unprognostic (8.34e-2)" "unprognostic (2.54e-1)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (1.51e-4)" "unprognostic (3.95e-3)" "unprognostic (1.90e-1)" "validated prognostic favorable (7.96e-6)" "validated prognostic favorable (1.67e-5)" "unprognostic (8.30e-3)" "unprognostic (2.10e-1)" "unprognostic (1.12e-2)" "unprognostic (7.76e-2)" "unprognostic (7.21e-3)" "unprognostic (1.17e-1)" "unprognostic (2.48e-1)" "unprognostic (7.07e-2)" "unprognostic (3.38e-1)" "unprognostic (2.83e-2)" "unprognostic (1.70e-1)" "unprognostic (1.62e-1)" "unprognostic (4.01e-2)" "unprognostic (1.64e-3)" "unprognostic (8.45e-2)" "unprognostic (2.49e-1)" "unprognostic (9.37e-2)" "unprognostic (6.44e-2)" "unprognostic (6.07e-2)" PLEKHJ1 FLJ10297 ENSG00000104886 "Pleckstrin homology domain containing J1" Q9NW61 19 2230084-2237704 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 305.2;Enteric transient amplifying cells: 246.6;Enterocytes: 319.0;Paneth cells: 212.7" "Cell type enhanced" "Detected in all" "Enterocytes: 319.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 329396.5;Pancreatic islets: 248584.6" "Not detected" "Not detected" HPA048989 Approved Approved Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 Mitochondria "HPA048989: " "unprognostic (1.30e-1)" "unprognostic (9.77e-2)" "unprognostic (1.46e-1)" "unprognostic (3.38e-2)" "unprognostic (2.06e-1)" "unprognostic (1.18e-1)" "unprognostic (3.34e-1)" "unprognostic (7.79e-2)" "unprognostic (8.52e-2)" "unprognostic (3.02e-1)" "unprognostic (4.10e-3)" "unprognostic (1.22e-1)" "unprognostic (2.50e-2)" "unprognostic (1.56e-3)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (2.21e-2)" "unprognostic (5.94e-2)" "unprognostic (1.47e-2)" "unprognostic (4.40e-1)" "unprognostic (2.66e-1)" "unprognostic (1.64e-1)" "unprognostic (5.67e-2)" "unprognostic (4.59e-2)" "unprognostic (8.02e-3)" "unprognostic (1.41e-1)" "unprognostic (5.68e-2)" "unprognostic (3.28e-1)" "unprognostic (5.90e-3)" "unprognostic (1.14e-1)" "unprognostic (4.88e-2)" "unprognostic (1.03e-1)" PLEKHO1 "CKIP-1, OC120" ENSG00000023902 "Pleckstrin homology domain containing O1" Q53GL0 1 150149183-150164720 "Predicted intracellular proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 189.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.5;cDC: 226.4;Early spermatids: 256.2;Late primary spermatocytes: 292.1;Late spermatids: 525.8;Megakaryocytes: 197.8;Platelets: 1194.6;Smooth muscle cells: 349.4;Vascular smooth muscle cells: 167.9" "Cell type enhanced" "Detected in many" "Platelets: 1194.6;Smooth muscle cells: 349.4;Spermatogenic cell types: 525.8" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 169.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 2603876.6" "Tissue enhanced" "Detected in many" "fallopian tube: 3846922.6" HPA061018 Supported Mitochondria NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 15: Non-specific - Transcription" "Cluster 35: RS4;11 - Unknown function" "Cluster 47: Platelets - Hemostasis" 34 Mitochondria "HPA061018: " "unprognostic (3.84e-2)" "unprognostic (3.27e-3)" "unprognostic (2.17e-2)" "unprognostic (4.16e-2)" "unprognostic (5.47e-2)" "unprognostic (2.91e-1)" "unprognostic (3.86e-1)" "potential prognostic favorable (2.34e-4)" "unprognostic (1.26e-1)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (6.27e-5)" "unprognostic (2.48e-1)" "unprognostic (2.07e-1)" "unprognostic (2.79e-2)" "unprognostic (4.31e-2)" "unprognostic (6.79e-2)" "unprognostic (5.63e-2)" "unprognostic (8.22e-2)" "unprognostic (1.32e-1)" "unprognostic (1.02e-1)" "unprognostic (8.57e-2)" "unprognostic (3.60e-2)" "unprognostic (3.44e-2)" "unprognostic (1.13e-1)" "unprognostic (3.69e-2)" "unprognostic (6.36e-2)" "unprognostic (3.19e-2)" "unprognostic (3.74e-2)" "unprognostic (1.78e-1)" "unprognostic (2.30e-1)" "unprognostic (4.13e-2)" PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502192-4518486 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 715.6;breast: 303.4;skeletal muscle: 235.5" "Cell type enriched" "Detected in many" 9 "Adipocytes: 518.0" "Cell type enriched" "Detected in many" 9 "Adipocytes: 518.0" "Group enriched" "Detected in some" 4 "astrocyte: 21.7;Bergmann glia: 6.0;ependymal cell: 6.1" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 4.6" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Adipocytes (Minor salivary gland), Prostate - Smooth muscle cells, Skin - Adipocytes (Skin), Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" "Capillaries: 216926754.0;Cardiomyocytes: 357797217.1;Skeletal myofibers: 423896290.7" "Low tissue specificity" "Detected in many" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 130000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: , HPA054657: " "unprognostic (6.31e-2)" "unprognostic (4.31e-2)" "potential prognostic favorable (3.46e-4)" "unprognostic (2.70e-1)" "unprognostic (7.75e-2)" "unprognostic (2.96e-1)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "potential prognostic favorable (8.34e-4)" "unprognostic (1.14e-1)" "unprognostic (8.14e-3)" "unprognostic (5.45e-2)" "unprognostic (1.81e-1)" "unprognostic (1.89e-2)" "unprognostic (1.71e-2)" "unprognostic (4.13e-2)" "unprognostic (2.07e-2)" "unprognostic (1.37e-2)" "unprognostic (1.52e-1)" "unprognostic (7.04e-3)" "unprognostic (5.68e-2)" "unprognostic (2.28e-3)" PLIN5 "LSDA5, LSDP5, MLDP, OXPAT" ENSG00000214456 "Perilipin 5" Q00G26 19 4522531-4535224 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 199.6;skeletal muscle: 142.3" "Cell type enhanced" "Detected in many" "Adipocytes: 150.3;Hepatocytes: 148.8;Lacrimal acinar cells: 177.5;Myonuclei: 177.4;Neutrophils: 156.4;Pancreatic acinar cells: 157.0;Proximal tubule cells: 85.7;Salivary acinar cells: 155.4" "Cell type enhanced" "Detected in many" "Acinar cells: 177.5;Adipocytes: 150.3;Hepatocytes: 148.8;Myocytes: 177.4;Neutrophils: 156.4" "Cell type enhanced" "Detected in many" "astrocyte: 56.0;Bergmann glia: 27.5;choroid plexus epithelial cell: 29.8" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 23.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.8" "Lineage enriched" "Detected in single" 23 "granulocytes: 13.8" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Skin - Sebaceous gland cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Keratinocytes: 40506678.0;Skeletal myofibers: 33370756.5" "Tissue enhanced" "Detected in many" "skeletal muscle: 13045050.7" HPA077050 Supported "Vesicles,Lipid droplets" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 70: Non-specific - Protein processing" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 11: Neuronal - Sensory perception" "Cluster 55: Myocytes - Oxidative muscle function" 2 "Vesicles, Lipid droplets" "HPA077050: " "unprognostic (5.84e-3)" "unprognostic (3.87e-3)" "unprognostic (4.04e-2)" "unprognostic (1.01e-1)" "potential prognostic favorable (3.26e-4)" "unprognostic (1.26e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (7.60e-2)" "unprognostic (2.38e-2)" "unprognostic (3.51e-3)" "potential prognostic favorable (5.40e-4)" "unprognostic (1.09e-3)" "unprognostic (1.41e-2)" "unprognostic (5.95e-2)" "unprognostic (2.30e-2)" "unprognostic (6.41e-2)" "unprognostic (2.50e-1)" "unprognostic (3.33e-1)" "unprognostic (1.97e-3)" "unprognostic (2.13e-1)" "unprognostic (1.18e-1)" "unprognostic (8.62e-2)" "unprognostic (1.18e-1)" "unprognostic (1.30e-1)" "unprognostic (2.32e-2)" PLK2 SNK ENSG00000145632 "Polo like kinase 2" Q9NYY3 5 58453982-58460139 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 247.1;Breast secretory cells: 163.6;Endometrial glandular cells: 159.4;Endometrial luminal cells: 165.9;Endometrial secretory cells: 205.2;Epididymal basal cells: 262.5;Extravillous trophoblasts: 389.9" "Cell type enhanced" "Detected in many" "Basal cells: 262.5;Trophoblast cells: 389.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "NK-cell: 9.1" "Lineage enriched" "Detected in many" 4 "NK-cells: 9.1" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 116 "Neurons: 11555.6" "Tissue enriched" "Detected in single" 9272 "skeletal muscle: 927206.8" "CAB009624, HPA069329" Approved Approved Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 20: Non-specific - Transcription regulation" 7 "Nucleoplasm, Mitochondria, Cytosol" "CAB009624: , HPA069329: " "unprognostic (7.56e-2)" "unprognostic (5.58e-2)" "unprognostic (2.28e-1)" "unprognostic (2.30e-2)" "unprognostic (3.38e-1)" "unprognostic (6.25e-2)" "unprognostic (1.24e-3)" "unprognostic (5.17e-1)" "unprognostic (8.13e-2)" "unprognostic (7.04e-2)" "unprognostic (1.32e-2)" "unprognostic (1.56e-2)" "unprognostic (3.63e-2)" "unprognostic (4.64e-2)" "unprognostic (2.01e-3)" "unprognostic (1.43e-1)" "unprognostic (5.84e-3)" "unprognostic (1.69e-1)" "unprognostic (6.50e-2)" "unprognostic (2.77e-2)" "unprognostic (7.19e-3)" "unprognostic (1.78e-1)" "unprognostic (3.90e-3)" "unprognostic (3.29e-1)" "unprognostic (1.16e-1)" "unprognostic (6.32e-2)" "unprognostic (6.43e-2)" "unprognostic (1.86e-1)" "unprognostic (2.51e-1)" "unprognostic (2.13e-1)" "unprognostic (2.43e-1)" PLK4 "Sak, STK18" ENSG00000142731 "Polo like kinase 4" O00444 4 127880893-127899224 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" Dwarfism "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 21.3;lymphoid tissue: 13.4;testis: 21.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 28.7;Early spermatids: 63.2;Erythrocyte progenitors: 61.9;Late primary spermatocytes: 104.4;Late spermatids: 139.2;Megakaryocyte progenitors: 34.8;Monocyte progenitors: 47.4;Neutrophil progenitors: 32.2;Respiratory deuterosomal cells: 69.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 69.5;Erythrocytes: 61.9;Mononuclear phagocytes: 47.4;Spermatogenic cell types: 139.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 1060 "cerebral cortex: 105977.5" "HPA017327, HPA035026, HPA043198" Approved Supported Centrosome,Cytosol NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 24: Neurons - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 42 Centrosome Cytosol "HPA017327: , HPA035026: , HPA043198: " "unprognostic (2.64e-2)" "unprognostic (2.17e-1)" "unprognostic (7.67e-2)" "unprognostic (2.30e-1)" "unprognostic (3.52e-3)" "unprognostic (3.23e-1)" "unprognostic (3.77e-1)" "unprognostic (2.01e-2)" "unprognostic (3.68e-1)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (3.64e-2)" "unprognostic (5.21e-2)" "unprognostic (3.50e-2)" "validated prognostic unfavorable (4.39e-5)" "validated prognostic unfavorable (1.10e-4)" "validated prognostic unfavorable (9.07e-5)" "validated prognostic unfavorable (3.77e-4)" "unprognostic (2.70e-1)" "unprognostic (2.25e-1)" "unprognostic (1.13e-1)" "unprognostic (3.65e-2)" "unprognostic (1.10e-3)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (2.17e-2)" "unprognostic (1.09e-3)" "unprognostic (7.91e-2)" "unprognostic (3.68e-2)" "unprognostic (4.86e-2)" "unprognostic (2.56e-1)" "unprognostic (2.63e-2)" "unprognostic (6.97e-2)" PLPP3 "LPP3, PAP-2b, PPAP2B" ENSG00000162407 "Phospholipid phosphatase 3" O14495 1 56494761-56645301 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 279.4;Bergmann glia: 304.5;Cardiomyocytes: 301.3;Endometrial stromal cells: 325.2;Fibro-adipogenic progenitors: 291.9;Fibroblasts: 291.8;Leydig cells: 598.7;Pericytes: 262.3;Salivary myoepithelial cells: 273.9;Vascular endothelial cells: 275.2;Vascular smooth muscle cells: 284.0" "Cell type enhanced" "Detected in many" "Leydig cells: 598.7" "Cell type enhanced" "Detected in all" "astrocyte: 313.9;Bergmann glia: 310.9" "Cancer enhanced" "Detected in all" "Thyroid Carcinoma (TCGA): 405.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.4;naive B-cell: 2.3" "Lineage enriched" "Detected in single" 6 "B-cells: 2.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 65.5" "Kidney - Endothelial cells, Prostate - Fibroblasts, Skin - Fibroblasts_2, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 7750472.4" "Group enriched" "Detected in many" "cerebral cortex: 3735152.0;fallopian tube: 2153390.6;skin: 1361679.3" HPA072751 Approved Supported "Golgi apparatus,Mid piece,Principal piece" NA Yes "Cluster 23: B-cells - Immunoglobulins" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 103: Non-specific - Basic cellular processes" 7 "Golgi apparatus" "Mid piece, Principal piece" "HPA072751: " "unprognostic (1.22e-2)" "unprognostic (8.74e-2)" "unprognostic (9.95e-2)" "unprognostic (1.81e-1)" "unprognostic (5.20e-3)" "unprognostic (1.46e-1)" "unprognostic (1.28e-2)" "unprognostic (2.81e-3)" "unprognostic (1.48e-1)" "validated prognostic favorable (3.94e-13)" "validated prognostic favorable (5.01e-7)" "unprognostic (3.43e-1)" "unprognostic (1.91e-2)" "unprognostic (8.13e-2)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (8.05e-2)" "unprognostic (2.24e-2)" "unprognostic (5.66e-3)" "unprognostic (5.63e-2)" "unprognostic (1.87e-2)" "unprognostic (2.20e-1)" "unprognostic (1.26e-2)" "unprognostic (3.84e-2)" "unprognostic (1.58e-1)" "unprognostic (1.40e-2)" "unprognostic (1.55e-1)" "unprognostic (7.51e-2)" "unprognostic (3.93e-1)" PLPP5 "DPPL1, HTPAP, PPAPDC1B" ENSG00000147535 "Phospholipid phosphatase 5" Q8NEB5 8 38263130-38269243 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 232.3;Gastric chief cells: 180.2;Plasma cells: 303.7;Prostatic glandular cells: 168.9" "Cell type enhanced" "Detected in all" "Plasma cells: 303.7" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 82.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 8 "basophil: 80.7;memory B-cell: 212.7;naive B-cell: 307.0" "Group enriched" "Detected in all" 7 "B-cells: 307.0;granulocytes: 80.7" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 14754 "Pancreas epithelial cells: 2249772.1;Pancreatic islets: 700939.1" "Tissue enriched" "Detected in single" 12784 "salivary gland: 1278359.6" HPA055777 Approved Vesicles NA NA "Cluster 32: Basophils - Transcription" "Cluster 8: Pancreas - Proteolysis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 1 Vesicles "HPA055777: " "unprognostic (2.57e-2)" "unprognostic (2.06e-3)" "unprognostic (1.56e-1)" "unprognostic (4.84e-1)" "unprognostic (2.77e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (8.44e-2)" "unprognostic (2.84e-2)" "unprognostic (1.45e-1)" "unprognostic (2.13e-2)" "unprognostic (1.24e-2)" "potential prognostic unfavorable (3.26e-4)" "unprognostic (1.98e-2)" "unprognostic (1.85e-1)" "unprognostic (6.70e-2)" "unprognostic (1.29e-2)" "unprognostic (5.59e-3)" "unprognostic (1.29e-2)" "unprognostic (1.93e-1)" "unprognostic (7.05e-2)" "unprognostic (2.72e-2)" "unprognostic (4.19e-2)" "unprognostic (1.43e-1)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.47e-1)" "unprognostic (2.19e-2)" "unprognostic (2.46e-1)" PLPP6 "FLJ46512, FLJ90191, PDP1, PPAPDC2" ENSG00000205808 "Phospholipid phosphatase 6" Q8IY26 9 4662294-4665258 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Immunity, Innate immunity, Lipid metabolism" "Hydrolase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 24.1;Early spermatids: 110.2;Late spermatids: 63.5" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 110.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - B-cells (Spleen), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 1952861.3" "Group enriched" "Detected in some" 6512 "cerebral cortex: 542345.4;liver: 968192.9;lymphoid tissue: 442985.9" HPA018096 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 46 "Nucleoplasm, Vesicles" Cytosol "HPA018096: " "unprognostic (1.09e-2)" "unprognostic (4.32e-2)" "unprognostic (1.32e-1)" "unprognostic (2.61e-1)" "unprognostic (1.14e-1)" "unprognostic (2.06e-1)" "unprognostic (1.43e-1)" "unprognostic (1.50e-2)" "unprognostic (2.41e-1)" "potential prognostic favorable (2.05e-4)" "unprognostic (1.54e-1)" "unprognostic (9.08e-2)" "unprognostic (3.40e-2)" "unprognostic (9.26e-2)" "unprognostic (1.07e-1)" "unprognostic (9.07e-2)" "unprognostic (4.11e-2)" "unprognostic (7.33e-2)" "unprognostic (2.61e-1)" "unprognostic (1.76e-1)" "unprognostic (1.62e-1)" "unprognostic (1.06e-1)" "unprognostic (4.02e-2)" "unprognostic (1.15e-1)" "unprognostic (5.78e-3)" "unprognostic (3.03e-1)" "unprognostic (1.09e-1)" "unprognostic (5.99e-2)" "unprognostic (5.48e-2)" PLPP7 "C9orf67, FLJ14662, MGC12921, NET39, PPAPDC3" ENSG00000160539 "Phospholipid phosphatase 7 (inactive)" Q8NBV4 9 131289459-131359022 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "heart muscle: 87.4;skeletal muscle: 196.8;tongue: 69.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 84.4;Extravillous trophoblasts: 67.3;Myonuclei: 282.1;Oocytes: 69.1;Retinal amacrine cells: 107.4;Retinal bipolar cells: 222.8;Retinal ganglion cells: 38.6" "Cell type enhanced" "Detected in many" "Myocytes: 282.1;Neuronal cells: 222.8;Oocytes: 69.1" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 5.9;Rhabdoid: 5.8" "Heart muscle - Cardiomyocytes, Kidney - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Capillaries: 692722.0;Cardiomyocytes: 602440.0" "Tissue enriched" "Detected in some" "heart muscle: 152823.6" HPA070252 Uncertain Uncertain Nucleoplasm,Vesicles No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" "Nucleoplasm, Vesicles" "HPA070252: " "unprognostic (6.60e-2)" "unprognostic (2.11e-1)" "unprognostic (1.18e-1)" "unprognostic (1.62e-1)" "unprognostic (3.08e-1)" "unprognostic (1.13e-1)" "unprognostic (1.14e-1)" "unprognostic (6.16e-3)" "unprognostic (5.26e-2)" "potential prognostic favorable (5.00e-4)" "unprognostic (8.72e-3)" "unprognostic (6.61e-2)" "unprognostic (1.55e-2)" "unprognostic (3.63e-2)" "unprognostic (1.16e-1)" "unprognostic (2.65e-2)" "unprognostic (4.20e-2)" PLPPR1 "FLJ20300, LPPR1, MGC26189, PRG-3" ENSG00000148123 "Phospholipid phosphatase related 1" Q8TBJ4 9 101028727-101325135 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 24.7;kidney: 14.6" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 78.6;Brain inhibitory neurons: 291.4;Distal convoluted tubule cells: 344.5;Loop of henle epithelial cells: 96.4;Oligodendrocyte progenitor cells: 804.1;Oligodendrocytes: 553.6;Other brain neurons: 73.6;Proximal tubule cells: 157.9;Renal collecting duct intercalated cells: 101.0" "Group enriched" "Detected in some" 4 "Glial cells: 804.1;Neuronal cells: 291.4;Renal nephron cells: 344.5" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 1085.9;oligodendrocyte precursor cell: 885.3" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 16.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "lung cancer: 1.1" "Liver - Hepatocytes, Pancreas - Alpha cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Glomeruli: 24790.2;Proximal tubules: 70092.8" "Tissue enriched" "Detected in single" 924 "cerebral cortex: 92425.8" "HPA014760, HPA014968, HPA014979" Supported Supported Nucleoplasm NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 14 Nucleoplasm "HPA014760: , HPA014968: , HPA014979: " "unprognostic (2.02e-1)" "unprognostic (1.05e-3)" "unprognostic (2.73e-1)" "unprognostic (2.26e-2)" "unprognostic (3.06e-1)" "unprognostic (1.21e-3)" "unprognostic (1.83e-2)" "unprognostic (6.90e-2)" "unprognostic (3.21e-2)" "unprognostic (2.47e-1)" "unprognostic (2.62e-1)" PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 451.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 502.2;Esophageal apical cells: 826.7;Esophageal suprabasal cells: 316.3;Ocular epithelial cells: 414.1;Suprabasal keratinocytes: 344.1;Urothelial cells: 349.1;Vascular smooth muscle cells: 368.9" "Cell type enhanced" "Detected in many" "Alveolar cells: 502.2;Apical squamous epithelial cells: 826.7" "Cell type enhanced" "Detected in many" "vascular associated smooth muscle cell: 445.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "NK-cell: 3.8;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 5 "dendritic cells: 12.2;NK-cells: 3.8" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 267232084.7" "Tissue enhanced" "Detected in all" "blood vessel: 521023247.3" "HPA000895, HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 88000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 19 "Plasma membrane, Cytosol" "HPA000895: , HPA020433: , HPA076083: " "unprognostic (2.96e-3)" "unprognostic (2.94e-2)" "unprognostic (2.32e-1)" "unprognostic (1.31e-3)" "unprognostic (3.81e-1)" "unprognostic (2.41e-2)" "unprognostic (7.78e-2)" "unprognostic (2.42e-3)" "potential prognostic unfavorable (4.21e-4)" "unprognostic (5.86e-3)" "unprognostic (3.85e-3)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (4.11e-5)" "unprognostic (4.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (3.70e-4)" "unprognostic (2.65e-1)" "unprognostic (3.73e-2)" "unprognostic (1.95e-1)" "unprognostic (8.66e-2)" "unprognostic (4.77e-3)" "unprognostic (9.43e-2)" "unprognostic (1.32e-1)" "unprognostic (8.52e-2)" "unprognostic (1.65e-1)" "unprognostic (1.68e-1)" "unprognostic (1.63e-2)" "unprognostic (1.95e-1)" "unprognostic (1.31e-1)" "unprognostic (2.08e-1)" PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction, Lipid transport, Transport" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 626.4;monocytes: 403.3;Neutrophil progenitors: 470.1;Neutrophils: 830.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 626.4;Neutrophils: 830.3" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 138.4;endothelial cell: 201.9;pericyte: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 11449965.5" "Tissue enriched" "Detected in many" "lymphoid tissue: 3157781.6" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes 47000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 81 "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB070421: , HPA068923: " "unprognostic (8.19e-2)" "unprognostic (1.57e-1)" "unprognostic (4.39e-1)" "unprognostic (7.66e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (1.00e-1)" "unprognostic (4.68e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "potential prognostic favorable (7.04e-6)" "unprognostic (2.53e-2)" "unprognostic (2.14e-1)" "unprognostic (5.61e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (2.96e-4)" "unprognostic (5.24e-3)" "unprognostic (1.04e-1)" "unprognostic (4.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (4.65e-3)" "unprognostic (1.43e-2)" "unprognostic (1.95e-1)" "unprognostic (5.68e-2)" "unprognostic (1.58e-1)" "unprognostic (1.03e-1)" "unprognostic (2.01e-1)" "unprognostic (2.15e-2)" "unprognostic (1.68e-1)" "unprognostic (2.86e-2)" PLSCR2 ENSG00000163746 "Phospholipid scramblase 2" Q9NRY7 3 146391421-146495991 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 12.7" "Group enriched" "Detected in many" 6 "Early spermatids: 300.2;Late primary spermatocytes: 120.8;Late spermatids: 437.5" "Cell type enriched" "Detected in many" 10 "Spermatogenic cell types: 437.5" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 5.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA051352 Supported "Nucleoplasm,Endoplasmic reticulum,Vesicles" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 11 Nucleoplasm "Endoplasmic reticulum, Vesicles" "HPA051352: " "unprognostic (8.52e-2)" "unprognostic (2.12e-2)" PLXDC2 "FLJ14623, TEM7R" ENSG00000120594 "Plexin domain containing 2" Q6UX71 10 19816239-20289856 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fibro-adipogenic progenitors: 1608.6;Macrophages: 1941.1;Megakaryocyte progenitors: 1608.3;Microglia: 7582.4;monocytes: 1654.0;Neutrophils: 2495.4" "Cell type enhanced" "Detected in all" "Glial cells: 7582.4" "Group enriched" "Detected in all" 6 "central nervous system macrophage: 9410.5;mammillary body: 2635.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 57.6;intermediate monocyte: 33.4;myeloid DC: 36.1;neutrophil: 81.8;non-classical monocyte: 37.5" "Group enriched" "Detected in many" 13 "dendritic cells: 36.1;granulocytes: 81.8;monocytes: 57.6" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Lung - Fibroblasts_1, Prostate - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 4589920.6" "Low tissue specificity" "Detected in all" "HPA017268, HPA070793" Approved Supported "Nuclear bodies" No No 85000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 2 "Nuclear bodies" "HPA017268: , HPA070793: " "unprognostic (6.21e-2)" "unprognostic (1.39e-1)" "unprognostic (4.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.87e-2)" "potential prognostic unfavorable (7.36e-4)" "unprognostic (6.50e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" "unprognostic (1.17e-1)" "potential prognostic favorable (1.91e-7)" "unprognostic (1.88e-1)" "unprognostic (3.06e-1)" "unprognostic (1.88e-2)" "unprognostic (5.16e-2)" "unprognostic (3.32e-2)" "unprognostic (2.81e-2)" "unprognostic (2.01e-2)" "unprognostic (9.65e-2)" "unprognostic (5.57e-3)" "unprognostic (4.65e-3)" "unprognostic (1.36e-1)" "unprognostic (3.65e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.02e-2)" "unprognostic (3.19e-3)" "unprognostic (6.35e-2)" "unprognostic (6.87e-2)" "unprognostic (3.15e-1)" PLXNA1 "NOV, PLXN1" ENSG00000114554 "Plexin A1" Q9UIW2 3 126982693-127037389 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Alveolar cells type 1: 165.5" "Cell type enriched" "Detected in many" 5 "Alveolar cells: 165.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 25012555.7;Microglia and Neuropil: 30803727.8;Neurons: 9515882.2" "Tissue enriched" "Detected in many" "cerebral cortex: 79731976.7" "HPA007499, CAB012483" Uncertain Approved "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA 22000000 "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" 42 "Nucleoplasm, Cytosol" "Centrosome, Basal body" "CAB012483: , HPA007499: " "unprognostic (2.12e-1)" "unprognostic (2.13e-1)" "unprognostic (2.44e-2)" "unprognostic (2.67e-2)" "unprognostic (1.62e-1)" "unprognostic (2.00e-1)" "unprognostic (9.97e-2)" "unprognostic (3.57e-1)" "unprognostic (9.32e-3)" "unprognostic (3.71e-2)" "unprognostic (3.11e-2)" "unprognostic (1.11e-3)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (1.92e-5)" "unprognostic (8.81e-2)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (6.41e-2)" "potential prognostic unfavorable (6.12e-4)" "unprognostic (2.71e-1)" "unprognostic (3.41e-3)" "potential prognostic unfavorable (4.38e-4)" "unprognostic (1.05e-1)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (1.39e-1)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (1.26e-3)" "unprognostic (1.17e-2)" PMEL "D12S53E, gp100, HMB-45, HMB45, ME20, Pmel17, SI, SIL, SILV" ENSG00000185664 "Premelanosome protein" P40967 12 55954105-55973317 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Melanin biosynthesis" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6;skin 1: 109.1" "Group enriched" "Detected in many" 51 "Melanocytes: 3051.8;Retinal pigment epithelial cells: 780.1" "Cell type enriched" "Detected in many" 82 "Pigment cells: 3051.8" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 552 "Skin Cutaneous Melanoma (TCGA): 7481.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 49 "skin cancer: 3389.1" "Liver - Hepatocytes, Skin - Melanocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA031649 Enhanced Supported "Endoplasmic reticulum,Golgi apparatus" "Intracellular and membrane" Other NA NA 4000000 "Cluster 37: Skin - Keratinization" "Cluster 15: Non-specific - Transcription" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" "Endoplasmic reticulum" "Golgi apparatus" "HPA031649: " "unprognostic (9.14e-2)" "unprognostic (2.57e-1)" "unprognostic (1.91e-1)" "unprognostic (2.05e-2)" "unprognostic (2.05e-2)" "unprognostic (2.50e-2)" "unprognostic (1.35e-1)" "unprognostic (1.65e-1)" "potential prognostic favorable (9.28e-4)" "unprognostic (1.25e-1)" "unprognostic (1.63e-1)" "unprognostic (3.91e-1)" "unprognostic (2.70e-2)" "unprognostic (7.93e-3)" "unprognostic (1.48e-1)" "unprognostic (7.72e-3)" "unprognostic (1.53e-1)" "unprognostic (2.29e-1)" "unprognostic (2.29e-2)" "unprognostic (2.05e-2)" "unprognostic (6.08e-2)" "unprognostic (1.04e-1)" "unprognostic (1.78e-2)" "unprognostic (9.68e-2)" "unprognostic (4.82e-2)" "unprognostic (2.84e-1)" "unprognostic (1.80e-1)" "unprognostic (9.29e-2)" "unprognostic (1.02e-1)" PMF1 ENSG00000160783 "Polyamine modulated factor 1" Q6P1K2 1 156212993-156240042 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 18.8;Bergmann glia: 28.0;Brain excitatory neurons: 14.3;Brain inhibitory neurons: 11.9;Choroid plexus epithelial cells: 33.8;Ependymal cells: 18.4;Gastric chief cells: 9.8;Microglia: 20.4;Oligodendrocyte progenitor cells: 23.5;Oligodendrocytes: 32.9;Other brain neurons: 12.0" "Group enriched" "Detected in many" 4 "Ciliated cells: 33.8;Gastric glandular cells: 9.8;Glial cells: 32.9;Neuronal cells: 14.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "intestine: 9647481.0;skeletal muscle: 13861566.0" "HPA034583, HPA071854" Supported "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 37 Nucleoplasm "Golgi apparatus, Vesicles" "HPA034583: , HPA071854: " "unprognostic (2.67e-2)" "unprognostic (6.35e-2)" "unprognostic (2.71e-1)" "unprognostic (3.55e-1)" "unprognostic (4.67e-2)" "unprognostic (1.33e-1)" "unprognostic (4.08e-2)" "unprognostic (2.50e-3)" "unprognostic (2.34e-2)" "unprognostic (1.46e-1)" "unprognostic (1.46e-3)" "unprognostic (1.78e-2)" "unprognostic (8.38e-3)" "unprognostic (1.55e-2)" "unprognostic (1.26e-2)" "unprognostic (2.94e-2)" "unprognostic (8.46e-2)" "unprognostic (3.04e-2)" "unprognostic (7.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.21e-1)" "unprognostic (5.26e-2)" "unprognostic (1.22e-1)" "unprognostic (2.20e-1)" "unprognostic (3.04e-1)" "unprognostic (3.27e-1)" "unprognostic (1.45e-1)" "unprognostic (4.58e-2)" "unprognostic (1.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.49e-1)" PMF1-BGLAP ENSG00000260238 "PMF1-BGLAP readthrough" 1 156212982-156243332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 6.1;Ovarian stromal cells: 6.9;Salivary basal cells: 7.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "HPA034583, HPA071854" Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 67: Plasma cells - Plasma cell differentiation" Nucleoplasm "Golgi apparatus, Vesicles" "HPA034583: , HPA071854: " "potential prognostic unfavorable (1.96e-4)" "unprognostic (2.07e-1)" "unprognostic (2.78e-1)" "unprognostic (3.83e-2)" "unprognostic (2.77e-1)" "unprognostic (3.36e-2)" "unprognostic (4.96e-2)" "unprognostic (1.24e-2)" "unprognostic (9.72e-2)" "unprognostic (1.69e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (5.03e-4)" "unprognostic (1.74e-2)" "unprognostic (2.35e-2)" "unprognostic (1.97e-2)" "unprognostic (3.76e-2)" "unprognostic (7.63e-2)" "unprognostic (1.24e-1)" "unprognostic (3.55e-2)" "unprognostic (1.44e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (1.32e-2)" "unprognostic (1.85e-1)" "unprognostic (3.73e-2)" "unprognostic (1.82e-2)" "unprognostic (2.01e-1)" PMFBP1 ENSG00000118557 "Polyamine modulated factor 1 binding protein 1" Q8TBY8 16 72112157-72176878 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 12.7;testis: 20.0" "Cell type enhanced" "Detected in many" "Early spermatids: 152.4;Late primary spermatocytes: 83.4;Late spermatids: 464.5;Paneth cells: 54.1;Retinal amacrine cells: 53.9;Retinal horizontal cells: 224.4" "Group enriched" "Detected in many" 6 "Neuronal cells: 224.4;Spermatogenic cell types: 464.5" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 13.3" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 20.7" "Region enhanced" "Detected in all" "pons: 30.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Skin - Sebaceous gland cells, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 10001 "skeletal muscle: 1000055.9" HPA075825 Approved Uncertain "Nucleoplasm,Cell Junctions,Acrosome,Connecting piece,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 109: Neurons - Neuronal signaling" 2 "Nucleoplasm, Connecting piece" "Cell Junctions, Acrosome, Flagellar centriole, Mid piece, Principal piece" "HPA075825: " "unprognostic (4.09e-2)" "unprognostic (2.94e-2)" "unprognostic (2.19e-2)" "unprognostic (2.94e-1)" "unprognostic (1.26e-1)" "unprognostic (1.08e-1)" "unprognostic (7.31e-2)" "potential prognostic unfavorable (1.34e-8)" "unprognostic (3.13e-1)" "unprognostic (7.98e-3)" "potential prognostic unfavorable (9.31e-4)" "unprognostic (1.46e-2)" "unprognostic (2.02e-1)" "unprognostic (2.57e-1)" "unprognostic (2.81e-1)" "unprognostic (2.70e-1)" "unprognostic (5.08e-3)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (7.23e-2)" "unprognostic (2.04e-1)" "unprognostic (4.78e-2)" "unprognostic (2.77e-1)" "unprognostic (4.20e-2)" PMM2 "CDG1, CDG1a, CDGS, PMI, PMI1" ENSG00000140650 "Phosphomannomutase 2" O15305 16 8788823-8862534 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 313.8;Late spermatids: 458.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 458.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 8 "basophil: 207.1" "Lineage enriched" "Detected in all" 12 "granulocytes: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 147042117.2" "Low tissue specificity" "Detected in all" HPA063649 Approved Approved "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Cytosol" NA NA 39000 "Cluster 46: Basophils - Proteolysis" "Cluster 70: Non-specific - Protein processing" "Cluster 36: Choroid plexus - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 2 "Nucleoplasm, Cytosol" "Microtubules, Primary cilium, Primary cilium tip" "HPA063649: " "unprognostic (1.37e-1)" "potential prognostic unfavorable (7.71e-5)" "unprognostic (6.45e-2)" "unprognostic (1.65e-1)" "unprognostic (2.93e-3)" "unprognostic (4.39e-2)" "unprognostic (1.40e-2)" "unprognostic (2.56e-1)" "unprognostic (1.04e-2)" "unprognostic (1.36e-1)" "validated prognostic unfavorable (6.21e-4)" "validated prognostic unfavorable (1.71e-4)" "unprognostic (2.06e-2)" "unprognostic (1.90e-3)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (8.93e-3)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (1.05e-1)" "unprognostic (1.08e-1)" "unprognostic (1.65e-1)" "unprognostic (1.72e-1)" "unprognostic (2.43e-2)" "unprognostic (4.53e-2)" "unprognostic (7.02e-2)" "unprognostic (4.00e-2)" "unprognostic (2.65e-1)" "unprognostic (1.63e-1)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (4.55e-3)" "unprognostic (1.57e-1)" PMPCA "Alpha-MPP, CLA1, INPP5E, KIAA0123, MAS2, SCAR2" ENSG00000165688 "Peptidase, mitochondrial processing subunit alpha" Q10713 9 136410630-136427992 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 125.9;Syncytiotrophoblasts: 126.4" "Cell type enhanced" "Detected in many" "Trophoblast cells: 126.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "heart muscle: 83887185.3" "HPA021648, HPA063735" Supported Enhanced Mitochondria NA NA 37000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 42 Mitochondria "HPA021648: , HPA063735: " "unprognostic (7.50e-3)" "unprognostic (8.18e-2)" "unprognostic (2.52e-1)" "unprognostic (4.40e-2)" "unprognostic (3.20e-1)" "unprognostic (2.42e-1)" "unprognostic (1.02e-1)" "unprognostic (2.75e-2)" "unprognostic (1.44e-1)" "unprognostic (4.73e-2)" "potential prognostic favorable (8.00e-5)" "unprognostic (5.78e-2)" "potential prognostic favorable (2.40e-4)" "unprognostic (2.23e-2)" "unprognostic (6.68e-2)" "unprognostic (5.13e-2)" "unprognostic (2.27e-1)" "unprognostic (2.30e-2)" "unprognostic (1.00e-1)" "unprognostic (8.82e-2)" "unprognostic (2.28e-1)" "potential prognostic favorable (5.06e-4)" "unprognostic (8.82e-2)" "unprognostic (1.28e-2)" "unprognostic (8.88e-2)" "unprognostic (2.17e-2)" "unprognostic (7.24e-2)" "unprognostic (3.03e-2)" "unprognostic (5.42e-2)" "unprognostic (4.77e-2)" "unprognostic (5.79e-3)" PMPCB "beta-MPP, MAS1, MPPB, MPPP52" ENSG00000105819 "Peptidase, mitochondrial processing subunit beta" O75439 7 103297407-103331818 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 231.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA040674, HPA074168" Approved Enhanced Mitochondria No No 6700 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 34 Mitochondria "HPA040674: , HPA074168: " "unprognostic (1.42e-1)" "unprognostic (3.62e-1)" "unprognostic (1.94e-2)" "unprognostic (2.35e-1)" "unprognostic (2.61e-1)" "unprognostic (8.02e-2)" "unprognostic (3.20e-3)" "unprognostic (6.91e-2)" "unprognostic (7.23e-2)" "unprognostic (1.09e-3)" "potential prognostic favorable (8.51e-5)" "unprognostic (6.54e-3)" "unprognostic (6.09e-2)" "unprognostic (7.49e-2)" "unprognostic (1.07e-2)" "unprognostic (6.38e-2)" "unprognostic (2.07e-1)" "unprognostic (1.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.80e-3)" "unprognostic (1.54e-1)" "unprognostic (1.83e-1)" "unprognostic (4.39e-2)" "unprognostic (8.52e-2)" "unprognostic (5.98e-2)" "unprognostic (3.15e-1)" "unprognostic (4.51e-2)" "unprognostic (1.33e-1)" "unprognostic (2.85e-1)" "unprognostic (8.58e-2)" "unprognostic (1.90e-1)" PMS1 "MLH2, PMSL1" ENSG00000064933 "PMS1 homolog 1, mismatch repair system component" P54277 2 189784085-189877629 "Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 45.4" "Cell type enhanced" "Detected in all" "Early spermatids: 506.1;Late primary spermatocytes: 327.1;Late spermatids: 992.8" "Cell type enriched" "Detected in all" 6 "Spermatogenic cell types: 992.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Fallopian tube cells: 1266781.3;Granulosa cells: 738122.9;Neurons: 2463660.5" "Tissue enriched" "Detected in some" "lymphoid tissue: 29509.7" HPA031013 Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 16 "Nuclear bodies" Nucleoplasm "HPA031013: " "unprognostic (3.68e-1)" "unprognostic (6.93e-2)" "unprognostic (1.49e-1)" "unprognostic (4.17e-2)" "unprognostic (6.84e-2)" "unprognostic (5.50e-2)" "unprognostic (1.35e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (1.44e-2)" "unprognostic (1.93e-1)" "unprognostic (2.50e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (5.73e-2)" "unprognostic (7.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.18e-2)" "unprognostic (5.84e-2)" "unprognostic (1.33e-2)" "unprognostic (1.49e-1)" "unprognostic (7.42e-2)" "unprognostic (9.16e-3)" "unprognostic (2.02e-1)" "unprognostic (4.31e-2)" "potential prognostic favorable (5.42e-4)" "unprognostic (2.79e-2)" "unprognostic (1.13e-1)" "unprognostic (5.11e-2)" "unprognostic (2.91e-3)" "unprognostic (1.71e-1)" PMS2 "H_DJ0042M02.9, HNPCC4, MLH4, PMS-2, PMSL2" ENSG00000122512 "PMS1 homolog 2, mismatch repair system component" P54278 7 5970925-6009130 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Disease variant, Hereditary nonpolyposis colorectal cancer, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 40.2;Proximal tubule cells: 37.2" "Cell type enhanced" "Detected in many" "Renal nephron cells: 40.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 4380125.3" "Group enriched" "Detected in some" "bone marrow: 488916.8;lymphoid tissue: 157124.9" "CAB010235, HPA070310" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 67: Non-specific - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" 14 Nucleoplasm Cytosol "CAB010235: , HPA070310: " "unprognostic (1.59e-2)" "unprognostic (2.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.46e-1)" "unprognostic (6.94e-3)" "unprognostic (4.54e-2)" "unprognostic (7.87e-2)" "unprognostic (2.09e-2)" "unprognostic (2.60e-1)" "unprognostic (1.31e-2)" "potential prognostic favorable (3.53e-4)" "unprognostic (2.32e-3)" "unprognostic (3.42e-3)" "unprognostic (2.99e-3)" "unprognostic (5.87e-2)" "unprognostic (9.14e-2)" "unprognostic (5.27e-2)" "unprognostic (3.26e-2)" "unprognostic (7.76e-2)" "unprognostic (2.64e-1)" "unprognostic (1.26e-2)" "unprognostic (4.10e-2)" "unprognostic (3.20e-3)" "unprognostic (7.36e-2)" "unprognostic (5.52e-3)" "unprognostic (7.63e-2)" "unprognostic (1.58e-1)" "unprognostic (8.54e-2)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (2.57e-4)" "unprognostic (2.00e-1)" PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669733-153689010 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 101.3;intestine: 78.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 40.8;Brain inhibitory neurons: 57.5;Cone photoreceptor cells: 60.0;Extravillous trophoblasts: 94.4;Migrating cytotrophoblasts: 76.3;Other brain neurons: 61.8;Retinal bipolar cells: 45.6;Rod photoreceptor cells: 34.8;Sertoli cells: 49.3;Smooth muscle cells: 89.6;Syncytiotrophoblasts: 79.1" "Cell type enhanced" "Detected in many" "Neuronal cells: 61.8;Reproductive supporting cells: 49.3;Smooth muscle cells: 89.6;Trophoblast cells: 94.4" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 90.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 16.6" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Skin - Smooth muscle cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 1401170.3;Neurons: 4260714.7" "Tissue enriched" "Detected in single" 12070 "cerebral cortex: 1207001.6" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA007458: " "unprognostic (8.79e-2)" "unprognostic (2.83e-1)" "unprognostic (3.40e-1)" "unprognostic (1.58e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (2.97e-4)" "unprognostic (8.00e-3)" "unprognostic (1.50e-1)" "unprognostic (4.02e-2)" "unprognostic (7.79e-2)" "unprognostic (9.63e-2)" "unprognostic (2.60e-2)" "unprognostic (3.49e-2)" "validated prognostic unfavorable (3.90e-4)" "validated prognostic unfavorable (6.65e-6)" "unprognostic (7.11e-2)" "unprognostic (1.37e-1)" "unprognostic (7.76e-2)" "unprognostic (4.17e-3)" "unprognostic (1.10e-1)" "unprognostic (1.29e-1)" "unprognostic (1.95e-1)" "unprognostic (9.11e-3)" "unprognostic (1.50e-2)" "unprognostic (5.30e-2)" "unprognostic (5.75e-2)" "unprognostic (5.27e-2)" "unprognostic (5.08e-3)" "unprognostic (3.72e-2)" "unprognostic (5.36e-2)" PNMA1 MA1 ENSG00000176903 "PNMA family member 1" Q8ND90 14 73711783-73714384 "Predicted intracellular proteins" "Tumor antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 73.4;Late primary spermatocytes: 145.5;Late spermatids: 81.5;Peritubular myoid cells: 75.2;Platelets: 344.2" "Cell type enhanced" "Detected in many" "Platelets: 344.2;Spermatogenic cell types: 145.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 18340546.7" "Group enriched" "Detected in some" "cerebral cortex: 912306.4;intestine: 2013873.3;ovary: 981061.8" "HPA003817, HPA015007" Enhanced Uncertain Nucleoplasm,Cytosol NA NA "Cluster 31: T-cells - T-cell receptor" "Cluster 73: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 47: Platelets - Hemostasis" 129 Cytosol Nucleoplasm "HPA003817: , HPA015007: " "unprognostic (2.14e-1)" "unprognostic (1.37e-1)" "unprognostic (3.72e-2)" "unprognostic (1.41e-1)" "unprognostic (4.64e-2)" "unprognostic (1.60e-2)" "unprognostic (2.66e-1)" "unprognostic (3.89e-2)" "potential prognostic unfavorable (7.46e-5)" "unprognostic (2.21e-2)" "potential prognostic favorable (3.04e-5)" "unprognostic (3.37e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.06e-2)" "unprognostic (2.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.41e-1)" "unprognostic (1.59e-1)" "unprognostic (1.03e-1)" "unprognostic (5.30e-2)" "unprognostic (4.55e-2)" "unprognostic (2.03e-1)" "unprognostic (9.13e-2)" "unprognostic (7.53e-3)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (5.77e-3)" "unprognostic (9.71e-2)" "unprognostic (2.90e-2)" "unprognostic (4.54e-2)" PNPLA2 "ATGL, desnutrin, FP17548, iPLA2zeta, TTS-2.2" ENSG00000177666 "Patatin like phospholipase domain containing 2" Q96AD5 11 818914-825573 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 487.2;breast: 357.1" "Cell type enhanced" "Detected in many" "Adipocytes: 370.0;Syncytiotrophoblasts: 216.0" "Cell type enhanced" "Detected in all" "Adipocytes: 370.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 5836065.4;Capillaries: 2798953.5" "Tissue enriched" "Detected in some" "bone marrow: 717864.3" "HPA055173, HPA062602, HPA075175" Approved Enhanced "Nucleoplasm,Lipid droplets" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 49: Hindbrain - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 17 "Lipid droplets" Nucleoplasm "HPA055173: , HPA062602: , HPA075175: " "unprognostic (7.91e-2)" "unprognostic (3.52e-2)" "unprognostic (2.05e-1)" "unprognostic (1.79e-1)" "unprognostic (1.39e-1)" "unprognostic (1.72e-2)" "unprognostic (3.49e-2)" "unprognostic (3.26e-2)" "unprognostic (5.60e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (4.49e-4)" "unprognostic (3.19e-2)" "unprognostic (3.86e-2)" "unprognostic (5.51e-2)" "unprognostic (4.68e-3)" "unprognostic (7.32e-3)" "unprognostic (4.60e-1)" "unprognostic (2.80e-3)" "unprognostic (1.06e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-1)" "unprognostic (9.27e-2)" "unprognostic (6.74e-2)" "unprognostic (1.20e-2)" "unprognostic (4.25e-2)" "unprognostic (1.37e-1)" "unprognostic (6.44e-2)" "unprognostic (2.10e-1)" "unprognostic (9.11e-2)" "unprognostic (7.18e-2)" "unprognostic (3.96e-2)" PNPLA6 "iPLA2delta, NTE, SPG39, sws" ENSG00000032444 "Patatin like phospholipase domain containing 6" Q8IY17 19 7534004-7561764 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Disease variant, Dwarfism, Hereditary spastic paraplegia, Hypogonadotropic hypogonadism, Intellectual disability, Neurodegeneration, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Kupffer cells: 123.0;Late primary spermatocytes: 108.8;Late spermatids: 192.9;Oocytes: 96.7" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 123.0;Spermatogenic cell types: 192.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA007522, HPA064773" Uncertain Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Endoplasmic reticulum, Cytosol" "HPA007522: , HPA064773: " "unprognostic (2.76e-2)" "unprognostic (2.50e-1)" "unprognostic (1.89e-3)" "unprognostic (9.73e-3)" "unprognostic (8.59e-2)" "unprognostic (6.31e-2)" "unprognostic (3.76e-1)" "unprognostic (3.51e-1)" "potential prognostic favorable (7.06e-4)" "unprognostic (9.03e-3)" "unprognostic (2.16e-3)" "unprognostic (3.19e-2)" "potential prognostic favorable (5.10e-5)" "unprognostic (1.29e-2)" "unprognostic (4.97e-2)" "unprognostic (1.74e-2)" "unprognostic (6.51e-2)" "unprognostic (1.26e-2)" "unprognostic (3.62e-1)" "unprognostic (5.19e-2)" "unprognostic (3.41e-1)" "potential prognostic favorable (1.52e-4)" "unprognostic (2.17e-3)" "unprognostic (1.93e-1)" "unprognostic (1.21e-1)" "unprognostic (4.97e-3)" "unprognostic (1.14e-2)" "unprognostic (2.21e-2)" "unprognostic (9.03e-2)" "unprognostic (1.55e-1)" "unprognostic (7.08e-2)" PNPLA8 "IPLA2-2, IPLA2G, iPLA2gamma" ENSG00000135241 "Patatin like phospholipase domain containing 8" Q9NP80 7 108470417-108569666 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial glandular cells: 530.5;monocytes: 515.5;Neutrophils: 1502.7" "Cell type enhanced" "Detected in all" "Neutrophils: 1502.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "lymphoid tissue: 8472729.0" HPA020083 Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 "Nucleoplasm, Cytosol" "Golgi apparatus" "HPA020083: " "unprognostic (1.40e-2)" "unprognostic (3.18e-2)" "potential prognostic unfavorable (9.54e-4)" "unprognostic (2.35e-1)" "unprognostic (2.01e-1)" "unprognostic (2.38e-1)" "unprognostic (4.22e-1)" "unprognostic (1.16e-1)" "unprognostic (1.13e-1)" "unprognostic (1.30e-2)" "potential prognostic favorable (1.34e-7)" "unprognostic (5.96e-3)" "unprognostic (6.82e-2)" "unprognostic (4.68e-2)" "unprognostic (5.75e-2)" "unprognostic (1.38e-1)" "unprognostic (3.61e-1)" "unprognostic (1.67e-1)" "unprognostic (2.19e-1)" "unprognostic (3.55e-2)" "unprognostic (3.14e-2)" "unprognostic (7.10e-2)" "unprognostic (1.45e-2)" "unprognostic (1.09e-1)" "unprognostic (3.00e-1)" "unprognostic (2.98e-1)" "unprognostic (3.26e-2)" "unprognostic (2.84e-2)" "unprognostic (3.59e-1)" "unprognostic (1.99e-2)" "unprognostic (9.29e-2)" PNPO PDXPO ENSG00000108439 "Pyridoxamine 5'-phosphate oxidase" Q9NVS9 17 47941506-47949308 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyridoxine biosynthesis" Oxidoreductase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 82.9" "Cell type enhanced" "Detected in many" "Ependymal cells: 11.0;Tuft cells: 11.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 54788481.1;Proximal tubules: 60419442.5" "Tissue enhanced" "Detected in all" "kidney: 267394279.4;liver: 289761711.8" "HPA023204, HPA027776" Enhanced Approved Nucleoplasm,Cytosol NA NA 410000 "Cluster 33: Non-specific - ATP binding" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 3 "Nucleoplasm, Cytosol" "HPA023204: , HPA027776: " "unprognostic (1.82e-2)" "unprognostic (2.99e-2)" "unprognostic (3.82e-2)" "unprognostic (2.22e-1)" "unprognostic (9.04e-2)" "unprognostic (1.05e-2)" "unprognostic (3.14e-1)" "unprognostic (1.42e-1)" "unprognostic (1.16e-1)" "unprognostic (1.58e-1)" "potential prognostic favorable (4.32e-5)" "unprognostic (1.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.76e-3)" "unprognostic (5.96e-2)" "unprognostic (2.43e-1)" "unprognostic (3.16e-2)" "unprognostic (1.46e-1)" "unprognostic (1.53e-1)" "unprognostic (1.58e-1)" "unprognostic (1.37e-2)" "unprognostic (8.92e-2)" "unprognostic (1.82e-1)" "unprognostic (3.35e-2)" "unprognostic (2.12e-2)" "unprognostic (3.86e-3)" "unprognostic (1.20e-1)" "unprognostic (2.44e-2)" "unprognostic (4.83e-2)" "unprognostic (2.26e-1)" "unprognostic (2.67e-1)" PNPT1 "DFNB70, old-35, OLD35, PNPase" ENSG00000138035 "Polyribonucleotide nucleotidyltransferase 1" Q8TCS8 2 55634061-55693863 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "mRNA processing, Transport" "Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, RNA-binding, Transferase" "Deafness, Disease variant, Neurodegeneration, Non-syndromic deafness, Primary mitochondrial disease, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "CAB033424, HPA034602, HPA034603" Supported Supported Mitochondria,Cytosol NA NA 4600 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 61: BICR 18 - Protein kinases" "Cluster 17: Non-specific - RNA processing" 36 Mitochondria Cytosol "CAB033424: , HPA034602: , HPA034603: " "unprognostic (1.49e-2)" "unprognostic (3.25e-2)" "unprognostic (2.40e-1)" "unprognostic (3.67e-1)" "unprognostic (2.29e-2)" "unprognostic (2.03e-1)" "unprognostic (2.58e-1)" "unprognostic (9.91e-3)" "unprognostic (6.20e-2)" "unprognostic (1.28e-1)" "unprognostic (3.06e-2)" "unprognostic (6.57e-2)" "unprognostic (1.64e-2)" "unprognostic (3.77e-3)" "potential prognostic unfavorable (2.00e-5)" "unprognostic (2.05e-1)" "unprognostic (3.08e-1)" "unprognostic (3.75e-1)" "unprognostic (1.80e-3)" "unprognostic (1.08e-1)" "unprognostic (7.69e-2)" "unprognostic (2.39e-1)" "unprognostic (2.67e-3)" "unprognostic (9.24e-2)" "unprognostic (1.82e-1)" "unprognostic (3.60e-2)" "unprognostic (2.39e-2)" "unprognostic (2.57e-1)" "unprognostic (2.89e-2)" "unprognostic (3.98e-1)" "unprognostic (5.85e-2)" PNRC2 ENSG00000189266 "Proline rich nuclear receptor coactivator 2" Q9NPJ4 1 23956839-23963462 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal basal cells: 330.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 636 "T-cells: 63647.1" "Not detected" "Not detected" "HPA027820, HPA045837" Uncertain Supported "Nucleoplasm,Golgi apparatus" No No "Cluster 32: Basophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 103: Non-specific - Basic cellular processes" 8 Nucleoplasm "Golgi apparatus" "HPA027820: , HPA045837: " "unprognostic (3.58e-2)" "unprognostic (2.63e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-2)" "unprognostic (5.29e-2)" "unprognostic (2.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.65e-3)" "unprognostic (1.04e-2)" "unprognostic (4.94e-2)" "validated prognostic favorable (2.22e-6)" "validated prognostic favorable (9.49e-5)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (4.30e-3)" "unprognostic (2.49e-2)" "unprognostic (6.74e-2)" "unprognostic (1.12e-1)" "unprognostic (1.58e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (7.68e-2)" "unprognostic (4.08e-2)" "potential prognostic unfavorable (2.63e-4)" "unprognostic (4.38e-2)" "unprognostic (3.29e-2)" "unprognostic (2.40e-2)" "unprognostic (1.25e-1)" "unprognostic (1.36e-1)" "unprognostic (2.30e-1)" "unprognostic (1.10e-1)" POGZ "KIAA0461, ZNF280E, ZNF635" ENSG00000143442 "Pogo transposable element derived with ZNF domain" Q7Z3K3 1 151402724-151459494 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair" DNA-binding "Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 7157199.1" "Tissue enhanced" "Detected in many" "cerebral cortex: 974391.8" "HPA006800, HPA008781" Enhanced Supported "Nucleoplasm,Plasma membrane,Basal body,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 103 Nucleoplasm "Plasma membrane, Basal body, Cytosol" "HPA006800: , HPA008781: " "unprognostic (9.66e-3)" "unprognostic (5.39e-2)" "unprognostic (7.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.81e-1)" "unprognostic (1.52e-2)" "unprognostic (8.59e-2)" "unprognostic (1.08e-2)" "unprognostic (5.69e-3)" "unprognostic (1.83e-3)" "unprognostic (9.57e-3)" "unprognostic (2.11e-3)" "unprognostic (9.64e-2)" "unprognostic (6.34e-2)" "unprognostic (5.60e-3)" "unprognostic (9.34e-2)" "unprognostic (1.83e-2)" "unprognostic (1.48e-1)" "unprognostic (1.67e-2)" "unprognostic (8.11e-2)" "unprognostic (3.01e-2)" "unprognostic (5.26e-2)" "unprognostic (5.87e-3)" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-2)" "unprognostic (9.95e-2)" "unprognostic (3.06e-1)" "unprognostic (5.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.81e-2)" POLD1 "CDC2, POLD" ENSG00000062822 "DNA polymerase delta 1, catalytic subunit" P28340 19 50384204-50418018 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Exonuclease, Hydrolase, Nuclease, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 30.9;Erythrocyte progenitors: 28.3;Tuft cells: 23.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 24989984.9;Hepatocytes: 21398023.9" "Low tissue specificity" "Detected in many" "CAB004375, HPA046524" Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 18: Non-specific - Translation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 71 Nucleoplasm Cytosol "CAB004375: , HPA046524: " "unprognostic (1.22e-1)" "unprognostic (3.40e-1)" "unprognostic (5.17e-2)" "unprognostic (1.21e-1)" "unprognostic (1.54e-1)" "unprognostic (2.83e-1)" "unprognostic (2.11e-1)" "unprognostic (1.20e-1)" "unprognostic (3.67e-2)" "unprognostic (9.89e-2)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (1.79e-2)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (7.56e-6)" "validated prognostic unfavorable (9.11e-5)" "potential prognostic unfavorable (7.56e-5)" "unprognostic (5.06e-2)" "unprognostic (3.74e-2)" "unprognostic (5.50e-2)" "unprognostic (4.22e-1)" "unprognostic (3.54e-2)" "unprognostic (2.66e-1)" "unprognostic (1.50e-1)" "unprognostic (1.05e-2)" "unprognostic (9.25e-2)" "unprognostic (1.81e-3)" "unprognostic (1.43e-2)" "unprognostic (9.62e-3)" "unprognostic (6.93e-2)" "unprognostic (3.00e-1)" "unprognostic (5.89e-2)" POLD4 "p12, POLDS" ENSG00000175482 "DNA polymerase delta 4, accessory subunit" Q9HCU8 11 67350772-67356972 "Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA excision, DNA repair, DNA replication" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 198.2" "Cell type enhanced" "Detected in many" "Colonocytes: 386.2;Enteric transient amplifying cells: 104.7;Enterocytes: 359.5;Esophageal apical cells: 93.3;Foveolar cells: 194.5;Goblet cells: 216.6" "Cell type enhanced" "Detected in many" "Enterocytes: 386.2;Gastric glandular cells: 194.5;Goblet cells: 216.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "lymphoid tissue: 119264.6" HPA078008 Approved "Centriolar satellite" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 12 "Centriolar satellite" "HPA078008: " "unprognostic (2.83e-1)" "unprognostic (1.69e-1)" "unprognostic (8.57e-2)" "unprognostic (2.18e-1)" "unprognostic (2.79e-1)" "unprognostic (8.84e-2)" "unprognostic (4.28e-3)" "unprognostic (6.81e-2)" "unprognostic (1.91e-2)" "unprognostic (2.28e-1)" "unprognostic (1.52e-3)" "unprognostic (9.63e-3)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (1.42e-1)" "unprognostic (1.48e-3)" "unprognostic (5.70e-3)" "unprognostic (4.43e-2)" "unprognostic (8.23e-3)" "unprognostic (4.25e-2)" "unprognostic (2.47e-2)" "unprognostic (1.12e-3)" "unprognostic (5.73e-2)" "unprognostic (1.08e-1)" "unprognostic (1.82e-1)" "unprognostic (6.76e-2)" "unprognostic (3.11e-1)" "unprognostic (1.21e-1)" "unprognostic (1.33e-2)" "unprognostic (3.28e-1)" "unprognostic (1.34e-1)" POLE2 DPE2 ENSG00000100479 "DNA polymerase epsilon 2, accessory subunit" P56282 14 49643555-49688422 "Essential proteins, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.3" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 81.7;Erythrocyte progenitors: 180.9;Megakaryocyte progenitors: 134.5;Megakaryocyte-Erythroid progenitors: 84.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 180.9;Megakaryocytes: 134.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 186695.1" "Not detected" "Not detected" HPA027555 Uncertain Supported "Nucleoplasm,Nuclear bodies,Vesicles" No No "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 24 "Nucleoplasm, Nuclear bodies" Vesicles "HPA027555: " "unprognostic (6.46e-2)" "unprognostic (3.63e-1)" "unprognostic (8.20e-3)" "unprognostic (7.30e-3)" "unprognostic (4.33e-2)" "unprognostic (7.58e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-1)" "unprognostic (2.10e-3)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (3.80e-2)" "unprognostic (6.68e-2)" "unprognostic (1.14e-1)" "validated prognostic unfavorable (2.63e-4)" "validated prognostic unfavorable (1.70e-4)" "potential prognostic unfavorable (7.54e-5)" "unprognostic (6.87e-3)" "unprognostic (1.31e-2)" "unprognostic (4.28e-1)" "unprognostic (1.04e-1)" "unprognostic (1.79e-3)" "validated prognostic unfavorable (4.67e-4)" "validated prognostic unfavorable (2.21e-4)" "unprognostic (4.53e-3)" "unprognostic (1.45e-3)" "unprognostic (2.80e-1)" "unprognostic (4.31e-3)" "unprognostic (1.64e-1)" "unprognostic (1.02e-1)" "unprognostic (2.62e-1)" "unprognostic (3.46e-2)" POLE3 "CHARAC17, CHRAC17, CHRAC2, p17, Ybl1" ENSG00000148229 "DNA polymerase epsilon 3, accessory subunit" Q9NRF9 9 113407235-113410675 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 225.4" "Cell type enhanced" "Detected in all" "Erythrocytes: 225.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 5018897.5;Neutrophils: 6461369.4;T-cells: 5381767.3" "Low tissue specificity" "Detected in many" "HPA004477, HPA047945" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 35 Nucleoplasm "Nucleoli, Cytosol" "HPA004477: , HPA047945: " "unprognostic (1.66e-1)" "unprognostic (1.60e-2)" "unprognostic (5.29e-2)" "unprognostic (4.67e-2)" "unprognostic (8.96e-2)" "unprognostic (1.92e-2)" "unprognostic (6.25e-3)" "unprognostic (1.59e-3)" "unprognostic (2.28e-2)" "unprognostic (2.34e-2)" "potential prognostic favorable (3.59e-7)" "unprognostic (3.35e-2)" "unprognostic (9.42e-2)" "validated prognostic unfavorable (9.31e-5)" "validated prognostic unfavorable (2.81e-4)" "unprognostic (7.02e-3)" "unprognostic (1.87e-3)" "unprognostic (1.23e-1)" "unprognostic (7.82e-2)" "unprognostic (3.32e-1)" "unprognostic (3.47e-1)" "unprognostic (9.74e-3)" "unprognostic (2.02e-1)" "unprognostic (1.42e-3)" "unprognostic (1.70e-1)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (4.19e-1)" "unprognostic (5.44e-3)" POLE4 p12 ENSG00000115350 "DNA polymerase epsilon 4, accessory subunit" Q9NR33 2 74958643-74970128 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" DNA-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 368.4;Parietal cells: 323.5" "Cell type enhanced" "Detected in all" "Oocytes: 368.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 28664111.9" "Group enriched" "Detected in some" 16333 "bone marrow: 2357571.7;ovary: 909039.3" "HPA054979, HPA071815, HPA076606" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 33: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 20 Nucleoplasm Cytosol "HPA054979: , HPA071815: , HPA076606: " "unprognostic (1.46e-3)" "unprognostic (6.77e-2)" "unprognostic (1.65e-1)" "unprognostic (9.30e-2)" "unprognostic (2.04e-1)" "unprognostic (3.01e-1)" "unprognostic (5.23e-2)" "unprognostic (6.59e-2)" "unprognostic (4.29e-2)" "unprognostic (1.25e-2)" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" "unprognostic (1.05e-2)" "validated prognostic unfavorable (8.82e-4)" "validated prognostic unfavorable (1.66e-6)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (6.32e-2)" "unprognostic (1.84e-1)" "unprognostic (1.29e-1)" "unprognostic (1.44e-1)" "unprognostic (8.33e-2)" "unprognostic (2.32e-1)" "unprognostic (5.04e-2)" "unprognostic (6.37e-2)" "unprognostic (2.29e-1)" "unprognostic (1.46e-1)" "unprognostic (1.61e-3)" "unprognostic (2.43e-3)" "unprognostic (2.98e-1)" "unprognostic (1.73e-1)" "unprognostic (6.28e-2)" POLK "DINB1, DINP, POLQ" ENSG00000122008 "DNA polymerase kappa" Q9UBT6 5 75511845-75609991 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, DNA synthesis" "DNA-binding, DNA-directed DNA polymerase, Mutator protein, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2753 "Collecting ducts: 200649.9;Granulosa cells: 302665.0;Neurons: 453681.5;Pancreas epithelial cells: 144314.7" "Not detected" "Not detected" "HPA012035, HPA057303, HPA068117, HPA069375" Enhanced Nucleoplasm NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 7: Non-specific - Transcription" 8 Nucleoplasm "HPA012035: , HPA057303: , HPA068117: , HPA069375: " "unprognostic (1.14e-2)" "unprognostic (2.78e-1)" "unprognostic (3.13e-1)" "unprognostic (2.90e-2)" "unprognostic (3.81e-2)" "unprognostic (1.23e-1)" "unprognostic (4.34e-1)" "unprognostic (2.04e-1)" "unprognostic (5.11e-2)" "unprognostic (7.55e-3)" "unprognostic (1.59e-3)" "unprognostic (3.46e-2)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (7.68e-2)" "unprognostic (1.42e-2)" "unprognostic (1.33e-1)" "unprognostic (2.23e-1)" "unprognostic (3.81e-1)" "unprognostic (1.59e-1)" "unprognostic (1.48e-3)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (4.08e-4)" "unprognostic (5.61e-2)" "unprognostic (7.27e-2)" "unprognostic (1.24e-1)" "unprognostic (1.39e-1)" "unprognostic (6.76e-3)" "unprognostic (2.28e-1)" "unprognostic (7.27e-2)" "unprognostic (1.96e-1)" POLM Tdt-N ENSG00000122678 "DNA polymerase mu" Q9NP87 7 44072062-44082530 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 63.8" "Lineage enriched" "Detected in all" 6 "granulocytes: 63.8" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 855221.2" "Tissue enriched" "Detected in single" 1281 "lymphoid tissue: 128104.8" "HPA058900, HPA078005" Supported Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 49: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" Nucleoplasm "HPA058900: , HPA078005: " "unprognostic (2.21e-2)" "unprognostic (8.74e-2)" "unprognostic (1.18e-1)" "unprognostic (1.62e-3)" "unprognostic (7.99e-3)" "unprognostic (1.18e-1)" "unprognostic (7.50e-2)" "unprognostic (2.31e-1)" "unprognostic (1.61e-1)" "unprognostic (3.51e-2)" "unprognostic (1.17e-2)" "unprognostic (1.45e-1)" "unprognostic (5.99e-2)" "unprognostic (5.84e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (2.97e-1)" "unprognostic (2.78e-1)" "unprognostic (4.99e-2)" "unprognostic (9.91e-2)" "unprognostic (9.39e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (6.63e-4)" "unprognostic (8.40e-2)" "unprognostic (3.14e-1)" "unprognostic (5.60e-2)" "unprognostic (2.91e-1)" "unprognostic (4.90e-2)" "unprognostic (1.28e-1)" "unprognostic (2.29e-1)" "unprognostic (2.96e-1)" POLR1C "AC40, RPA39, RPA40, RPA5, RPAC1, RPC40" ENSG00000171453 "RNA polymerase I and III subunit C" O15160 6 43509702-43562419 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 205.6;Epicardial cells: 236.5" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 236.5;Myocytes: 205.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" HPA031010 Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 215 "Nucleoplasm, Nucleoli fibrillar center" "HPA031010: " "unprognostic (5.75e-1)" "unprognostic (6.32e-3)" "unprognostic (5.86e-2)" "unprognostic (1.95e-1)" "unprognostic (1.95e-1)" "unprognostic (2.27e-1)" "unprognostic (1.63e-1)" "unprognostic (9.14e-3)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (7.94e-4)" "unprognostic (3.42e-3)" "unprognostic (5.03e-2)" "unprognostic (1.26e-2)" "unprognostic (3.57e-3)" "unprognostic (1.02e-3)" "unprognostic (2.49e-2)" "unprognostic (1.14e-2)" "unprognostic (3.46e-2)" "unprognostic (1.93e-2)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (1.59e-1)" "unprognostic (1.38e-1)" "unprognostic (4.33e-2)" "unprognostic (3.65e-3)" "unprognostic (6.52e-3)" "unprognostic (3.69e-3)" "unprognostic (7.23e-2)" "unprognostic (4.82e-2)" "unprognostic (2.74e-2)" "unprognostic (1.26e-2)" POLR2A "POLR2, POLRA, RPB1" ENSG00000181222 "RNA polymerase II subunit A" 17 7484366-7514616 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "lymphoid tissue: 1.5" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 74.5;Distal convoluted tubule cells: 56.5;Loop of henle epithelial cells: 71.4;Papillary tip epithelial cells: 62.0;Podocytes: 65.6;Proximal tubule cells: 48.6;Renal collecting duct intercalated cells: 91.5;Renal collecting duct principal cells: 80.2;Renal connecting tubule cells: 53.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 74.5;Ductal cells: 91.5;Renal nephron cells: 71.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 2.0" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012226, CAB016388, HPA021563, HPA053012" Enhanced Nucleoplasm,Cytosol NA Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 102: Non-specific - Mixed function" 207 Nucleoplasm Cytosol "CAB012226: , CAB016388: , HPA021563: , HPA053012: " "unprognostic (2.50e-1)" "unprognostic (9.01e-3)" "unprognostic (6.08e-2)" "unprognostic (8.51e-2)" "unprognostic (8.08e-2)" "unprognostic (3.71e-1)" "unprognostic (2.80e-2)" "unprognostic (1.58e-2)" "unprognostic (5.44e-1)" POLR2C RPB3 ENSG00000102978 "RNA polymerase II subunit C" P19387 16 57462660-57472009 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 13702964.0" "Tissue enhanced" "Detected in all" "intestine: 22931155.5" "HPA040919, HPA041826" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 164 Nucleoplasm Cytosol "HPA040919: , HPA041826: " "unprognostic (2.36e-1)" "unprognostic (1.06e-2)" "unprognostic (1.27e-2)" "unprognostic (8.19e-3)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (1.09e-1)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (1.95e-1)" "potential prognostic favorable (1.57e-9)" "unprognostic (8.39e-3)" "unprognostic (7.70e-3)" "unprognostic (2.03e-1)" "unprognostic (3.92e-1)" "unprognostic (5.22e-2)" "unprognostic (4.25e-2)" "unprognostic (1.99e-1)" "unprognostic (4.52e-3)" "unprognostic (3.24e-1)" "unprognostic (4.95e-2)" "unprognostic (2.12e-1)" "unprognostic (2.36e-1)" "unprognostic (1.92e-2)" "unprognostic (2.72e-2)" "unprognostic (3.91e-3)" "unprognostic (5.91e-2)" "unprognostic (2.54e-2)" "unprognostic (1.90e-1)" "unprognostic (7.67e-2)" "unprognostic (4.57e-1)" POLR2E "hRPB25, hsRPB5, RPABC1, RPB5, XAP4" ENSG00000099817 "RNA polymerase II, I and III subunit E" P19388 19 1086574-1095380 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Host-virus interaction, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 335.1;Esophageal suprabasal cells: 338.3;Extravillous trophoblasts: 297.4;Hofbauer cells: 344.8;Migrating cytotrophoblasts: 321.0;Oocytes: 478.9" "Cell type enhanced" "Detected in all" "Oocytes: 478.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA063030, HPA068992" Supported Supported Nucleoplasm NA NA 10000 "Cluster 29: Non-specific - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 318 Nucleoplasm "HPA063030: , HPA068992: " "unprognostic (6.81e-2)" "unprognostic (3.69e-1)" "unprognostic (1.42e-2)" "unprognostic (8.61e-2)" "unprognostic (4.22e-2)" "unprognostic (3.33e-1)" "unprognostic (1.63e-2)" "unprognostic (3.20e-1)" "unprognostic (5.83e-2)" "unprognostic (7.46e-2)" "potential prognostic favorable (7.63e-8)" "unprognostic (2.09e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (5.86e-5)" "unprognostic (3.64e-1)" "unprognostic (5.77e-2)" "unprognostic (2.02e-1)" "unprognostic (6.92e-2)" "unprognostic (3.00e-2)" "unprognostic (1.70e-1)" "unprognostic (6.83e-2)" "unprognostic (2.74e-1)" "unprognostic (2.52e-1)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (1.62e-2)" "unprognostic (3.95e-1)" "unprognostic (4.89e-3)" POLR2L "hRPB7.6, hsRPB10b, RBP10, RPABC5, RPB10beta, RPB7.6" ENSG00000177700 "RNA polymerase II, I and III subunit L" P62875 11 837356-842529 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RNA polymerase related proteins" Transcription "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 1884.3" "Cell type enhanced" "Detected in all" "Hepatocytes: 1884.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA073614 Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 147 Nucleoplasm "HPA073614: " "unprognostic (1.07e-3)" "unprognostic (3.30e-2)" "unprognostic (1.01e-1)" "unprognostic (6.20e-3)" "unprognostic (2.22e-1)" "unprognostic (2.65e-2)" "unprognostic (6.03e-2)" "unprognostic (7.03e-3)" "unprognostic (4.54e-2)" "unprognostic (2.62e-1)" "unprognostic (4.02e-2)" "unprognostic (9.16e-2)" "unprognostic (1.12e-3)" "potential prognostic unfavorable (1.75e-6)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (2.52e-2)" "unprognostic (1.38e-1)" "unprognostic (1.95e-1)" "unprognostic (4.06e-2)" "unprognostic (1.23e-1)" "unprognostic (1.21e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.18e-1)" "unprognostic (3.86e-2)" "unprognostic (2.88e-1)" "unprognostic (5.03e-3)" "unprognostic (1.09e-1)" "unprognostic (3.08e-3)" "unprognostic (1.47e-1)" POLR3B "C128, FLJ10388, RPC2" ENSG00000013503 "RNA polymerase III subunit B" Q9NW08 12 106357748-106510198 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Nucleotidyltransferase, Transferase" "Charcot-Marie-Tooth disease, Disease variant, Leukodystrophy, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 93.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Skin - Keratinocyte (other), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 859265.2" "Tissue enriched" "Detected in many" "intestine: 11895465.4" HPA036466 Supported Approved "Nuclear speckles" NA NA "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 106 "Nuclear speckles" "HPA036466: " "unprognostic (2.35e-1)" "unprognostic (3.29e-2)" "unprognostic (1.71e-1)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (6.65e-2)" "unprognostic (4.44e-2)" "unprognostic (5.75e-2)" "unprognostic (2.46e-2)" "unprognostic (8.03e-2)" "potential prognostic unfavorable (4.71e-4)" "potential prognostic favorable (5.09e-4)" "unprognostic (1.12e-1)" "unprognostic (1.55e-1)" "unprognostic (5.13e-2)" "unprognostic (2.82e-2)" "unprognostic (7.13e-2)" "unprognostic (5.18e-2)" "unprognostic (1.82e-1)" "unprognostic (3.81e-2)" "unprognostic (7.61e-2)" "unprognostic (4.45e-3)" "unprognostic (1.93e-1)" "unprognostic (1.96e-2)" "unprognostic (1.62e-1)" "unprognostic (7.18e-2)" "unprognostic (5.39e-2)" "unprognostic (6.61e-2)" "unprognostic (2.09e-1)" "unprognostic (2.45e-1)" "unprognostic (9.90e-2)" "unprognostic (9.14e-2)" POLR3D "BN51T, C53, RPC4, TSBN51" ENSG00000168495 "RNA polymerase III subunit D" P05423 8 22245133-22254601 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 74.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Large ducts: 5861463.7" "Tissue enriched" "Detected in some" "lung: 2392220.5" "HPA061331, HPA067875, HPA068461, HPA069089" Supported Enhanced Nucleoplasm NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 40: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 83 Nucleoplasm "HPA061331: , HPA067875: , HPA068461: , HPA069089: " "unprognostic (1.11e-2)" "unprognostic (1.85e-1)" "unprognostic (1.43e-3)" "unprognostic (2.62e-1)" "unprognostic (3.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (1.06e-2)" "unprognostic (1.27e-1)" "unprognostic (2.99e-2)" "unprognostic (1.99e-2)" "unprognostic (1.12e-2)" "unprognostic (5.11e-2)" "unprognostic (1.07e-3)" "unprognostic (6.23e-2)" "unprognostic (2.76e-2)" "unprognostic (2.11e-3)" "unprognostic (1.60e-1)" "unprognostic (6.95e-2)" "unprognostic (3.94e-1)" "unprognostic (4.85e-3)" "unprognostic (7.62e-2)" "unprognostic (1.27e-2)" "unprognostic (4.14e-1)" "unprognostic (1.27e-1)" "unprognostic (2.29e-3)" "unprognostic (3.26e-1)" "unprognostic (6.78e-2)" "unprognostic (1.64e-1)" "unprognostic (2.80e-2)" "unprognostic (9.32e-2)" POLR3K "C11, RPC11" ENSG00000161980 "RNA polymerase III subunit K" Q9Y2Y1 16 46407-53608 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RNA polymerase related proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Disease variant, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 75.5;Gastric progenitor cells: 88.4;Megakaryocytes: 74.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 72 "Collecting ducts: 10519.6;Granulosa cells: 3183.5;Oocytes: 7911.2" "Group enriched" "Detected in many" "lymphoid tissue: 992614.2;ovary: 463010.7;skeletal muscle: 729691.5" HPA005891 Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 81 Nucleoplasm Cytosol "HPA005891: " "unprognostic (3.68e-2)" "unprognostic (4.21e-2)" "unprognostic (2.40e-2)" "unprognostic (3.01e-1)" "unprognostic (1.24e-1)" "unprognostic (3.77e-3)" "unprognostic (2.46e-1)" "unprognostic (3.77e-1)" "unprognostic (2.29e-1)" "unprognostic (2.00e-2)" "unprognostic (7.23e-2)" "unprognostic (3.59e-1)" "unprognostic (1.45e-1)" "unprognostic (2.71e-3)" "potential prognostic unfavorable (5.18e-5)" "unprognostic (8.03e-2)" "unprognostic (3.52e-3)" "unprognostic (8.78e-3)" "unprognostic (1.33e-2)" "unprognostic (1.48e-1)" "unprognostic (1.31e-1)" "unprognostic (2.35e-2)" "unprognostic (1.65e-1)" "unprognostic (1.52e-1)" "unprognostic (1.56e-1)" "unprognostic (2.75e-1)" "unprognostic (8.94e-2)" "unprognostic (3.97e-2)" "unprognostic (1.14e-2)" "unprognostic (6.19e-2)" "unprognostic (1.37e-1)" POMT1 LGMD2K ENSG00000130714 "Protein O-mannosyltransferase 1" Q9Y6A1 9 131502789-131523806 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 84.5;Late primary spermatocytes: 76.8;Myonuclei: 72.8" "Cell type enhanced" "Detected in many" "Myocytes: 72.8;Spermatogenic cell types: 84.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 1421663.8" "Tissue enriched" "Detected in some" "fallopian tube: 214038.6" HPA065252 Uncertain "Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 29: Forebrain - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 "Golgi apparatus" "HPA065252: " "unprognostic (1.97e-1)" "unprognostic (1.79e-3)" "unprognostic (7.69e-2)" "unprognostic (4.55e-2)" "unprognostic (6.59e-2)" "unprognostic (6.91e-2)" "unprognostic (4.24e-1)" "potential prognostic favorable (1.53e-7)" "unprognostic (2.32e-1)" "unprognostic (2.48e-1)" "potential prognostic favorable (3.73e-8)" "unprognostic (7.45e-3)" "unprognostic (2.39e-3)" "unprognostic (5.90e-3)" "unprognostic (2.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-2)" "unprognostic (1.04e-2)" "unprognostic (1.23e-3)" "unprognostic (1.49e-1)" "unprognostic (2.05e-2)" "potential prognostic favorable (2.15e-4)" "unprognostic (9.46e-3)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (3.58e-1)" "unprognostic (2.25e-1)" "unprognostic (7.11e-2)" "unprognostic (1.11e-1)" "unprognostic (1.79e-2)" "unprognostic (1.96e-1)" POP4 RPP29 ENSG00000105171 "POP4 homolog, ribonuclease P/MRP subunit" O95707 19 29606283-29617237 "Essential proteins, Predicted intracellular proteins" "tRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 147.4;Late primary spermatocytes: 121.8;Oocytes: 96.7" "Cell type enhanced" "Detected in all" "Proliferating cells: 147.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 476379.0" "Group enriched" "Detected in some" 95 "lymphoid tissue: 11122.9;salivary gland: 7876.3" "HPA042748, HPA064577" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 39 "Nucleoplasm, Nucleoli" "HPA042748: , HPA064577: " "unprognostic (1.02e-1)" "unprognostic (1.60e-1)" "unprognostic (2.24e-1)" "unprognostic (2.76e-3)" "unprognostic (8.69e-2)" "unprognostic (9.55e-2)" "unprognostic (3.82e-3)" "unprognostic (6.05e-2)" "unprognostic (1.60e-1)" "unprognostic (8.82e-2)" "potential prognostic favorable (2.07e-5)" "unprognostic (2.82e-1)" "unprognostic (6.85e-2)" "unprognostic (6.83e-2)" "unprognostic (5.43e-3)" "unprognostic (6.54e-2)" "unprognostic (5.79e-2)" "unprognostic (7.00e-2)" "unprognostic (9.61e-2)" "unprognostic (4.80e-2)" "unprognostic (1.38e-2)" "unprognostic (4.86e-3)" "unprognostic (1.35e-1)" "unprognostic (1.30e-2)" "unprognostic (3.17e-2)" "unprognostic (2.30e-1)" "unprognostic (1.98e-2)" "unprognostic (1.76e-1)" "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (2.95e-2)" PORCN "DHOF, MG61, por, PORC, PPN" ENSG00000102312 "Porcupine O-acyltransferase" Q9H237 X 48508959-48520814 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 30.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 42.8;Endometrial secretory cells: 26.3;Esophageal apical cells: 99.7" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 42.8;Apical squamous epithelial cells: 99.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 6238732.6" "Group enriched" "Detected in some" "cerebral cortex: 2151825.9;lymphoid tissue: 611389.1" "HPA049215, HPA058413" Enhanced Approved Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Vesicles "HPA049215: , HPA058413: " "unprognostic (9.66e-2)" "unprognostic (2.31e-2)" "unprognostic (2.07e-1)" "unprognostic (6.53e-2)" "unprognostic (2.24e-1)" "unprognostic (2.01e-2)" "unprognostic (2.33e-1)" "unprognostic (2.64e-2)" "unprognostic (3.69e-1)" "unprognostic (2.50e-1)" "unprognostic (2.60e-2)" "unprognostic (3.26e-2)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (3.08e-5)" "unprognostic (5.97e-2)" "unprognostic (2.72e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (4.70e-2)" "unprognostic (8.98e-2)" "unprognostic (1.86e-2)" "unprognostic (2.71e-1)" "unprognostic (6.99e-2)" "unprognostic (6.05e-2)" "unprognostic (3.45e-1)" "unprognostic (9.33e-2)" "unprognostic (1.59e-2)" "unprognostic (2.01e-1)" "unprognostic (9.06e-2)" "unprognostic (7.00e-2)" "unprognostic (5.78e-2)" POU2AF2 "C11orf53, MGC50104, OCA-T1" ENSG00000150750 "POU class 2 homeobox associating factor 2" Q8IXP5 11 111245725-111286401 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "stomach 1: 2.9;testis: 4.9" "Group enriched" "Detected in some" 10 "Late primary spermatocytes: 60.2;Tuft cells: 219.0" "Group enriched" "Detected in many" 10 "Secretory gland support: 219.0;Spermatogenic cell types: 60.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 11.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 5.0" "Lung - Respiratory ciliated cells, Pancreas - Ductal cells, Stomach - Chief cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA056128, HPA073101" Uncertain Approved Nucleoplasm,Vesicles NA NA "Cluster 21: Testis - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 95: Tuft cells - Chemosensory signaling" Nucleoplasm Vesicles "HPA056128: , HPA073101: " "unprognostic (2.91e-2)" "unprognostic (2.36e-1)" "unprognostic (2.00e-2)" "unprognostic (1.93e-1)" "unprognostic (7.53e-2)" "unprognostic (1.21e-1)" "unprognostic (3.03e-3)" "unprognostic (2.63e-1)" "unprognostic (7.90e-3)" "unprognostic (2.20e-2)" "unprognostic (1.65e-1)" "unprognostic (2.22e-2)" "unprognostic (4.11e-2)" "unprognostic (2.76e-1)" POU2F1 "OCT1, OTF1" ENSG00000143190 "POU class 2 homeobox 1" P14859 1 167220876-167427345 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 4575917.7;Large ducts: 3459346.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 421354.7" "CAB002608, HPA028256, HPA058559, HPA064323" Supported Approved "Nucleoplasm,Endoplasmic reticulum,Vesicles" No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 15: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 39 Nucleoplasm "Endoplasmic reticulum, Vesicles" "CAB002608: , HPA028256: , HPA058559: , HPA064323: " "unprognostic (9.40e-2)" "unprognostic (7.87e-3)" "unprognostic (1.28e-1)" "unprognostic (1.48e-2)" "unprognostic (4.09e-2)" "unprognostic (9.02e-3)" "unprognostic (4.08e-2)" "unprognostic (1.58e-2)" "unprognostic (2.59e-2)" "unprognostic (6.31e-2)" "unprognostic (1.69e-3)" "unprognostic (4.46e-3)" "unprognostic (3.39e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (5.06e-2)" "unprognostic (3.47e-2)" "unprognostic (8.00e-2)" "unprognostic (6.45e-2)" "unprognostic (1.32e-2)" "unprognostic (3.00e-1)" "unprognostic (2.22e-1)" "unprognostic (8.00e-3)" "unprognostic (8.22e-3)" "unprognostic (2.01e-1)" "unprognostic (8.44e-2)" "unprognostic (1.56e-1)" "unprognostic (4.51e-1)" "unprognostic (1.19e-1)" "unprognostic (1.83e-1)" "unprognostic (1.41e-2)" "unprognostic (2.60e-2)" POU3F1 "OCT6, OTF6, SCIP" ENSG00000185668 "POU class 3 homeobox 1" Q03052 1 38043829-38046793 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 8.7;skin 1: 30.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 25.4;Bergmann glia: 31.6;Breast lactating cells: 24.0;Breast myoepithelial cells: 105.1;Epididymal basal cells: 84.3;Schwann cells: 50.9;Suprabasal keratinocytes: 33.8;Urothelial cells: 22.5" "Cell type enhanced" "Detected in many" "Basal cells: 84.3;Glial cells: 50.9;Secretory gland support: 105.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 35.7;hippocampal CA1-3: 47.1;miscellaneous: 31.3" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 5.9;Skin Cutaneous Melanoma (TCGA): 6.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Bone cancer: 19.8" "Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 9.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055980, HPA073824" Enhanced Nucleoplasm NA NA "Cluster 37: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 20: Non-specific - Transcription regulation" Nucleoplasm "HPA055980: , HPA073824: " "unprognostic (1.19e-1)" "unprognostic (1.98e-1)" "unprognostic (1.44e-2)" "unprognostic (2.17e-2)" "unprognostic (2.88e-2)" "unprognostic (1.60e-2)" "unprognostic (2.05e-1)" "unprognostic (1.35e-1)" "unprognostic (1.64e-1)" POU3F3 "BRN1, OTF8" ENSG00000198914 "POU class 3 homeobox 3" P20264 2 104853287-104858574 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 29.8;epididymis: 30.6;kidney: 43.4;seminal vesicle: 14.3" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 49.2;Loop of henle epithelial cells: 71.1;Papillary tip epithelial cells: 15.9;Proximal tubule cells: 26.3;Renal collecting duct intercalated cells: 23.0;Renal collecting duct principal cells: 40.3;Renal connecting tubule cells: 51.2" "Group enriched" "Detected in some" 18 "Ductal cells: 51.2;Renal nephron cells: 71.1" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.2;oligodendrocyte: 2.3;oligodendrocyte precursor cell: 1.9" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 42.6;Kidney Chromophobe (TCGA): 26.0;Kidney Renal Clear Cell Carcinoma (TCGA): 43.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 58.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 15.9;Uterine cancer: 8.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 3784 "Collecting ducts: 412871.9;Distal tubules: 344027.3" "Not detected" "Not detected" "HPA052792, HPA056039, HPA067151" Enhanced Enhanced Nucleoplasm NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" Nucleoplasm "HPA052792: , HPA056039: , HPA067151: " "unprognostic (3.46e-1)" "unprognostic (1.29e-1)" "unprognostic (2.97e-3)" "unprognostic (3.60e-2)" "validated prognostic favorable (1.90e-4)" "validated prognostic favorable (8.81e-5)" "unprognostic (4.79e-2)" "unprognostic (2.58e-1)" "unprognostic (1.60e-1)" "unprognostic (1.88e-1)" "unprognostic (9.47e-2)" POU5F1 "MGC22487, OCT-4, OCT3, Oct3/4, Oct4, OTF3" ENSG00000204531 "POU class 5 homeobox 1" Q01860 6 31164337-31180731 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.8" "Cell type enhanced" "Detected in some" "Endometrial glandular cells: 21.7;Endometrial luminal cells: 21.7;Loop of henle epithelial cells: 70.1;Papillary tip epithelial cells: 56.4;Proximal tubule cells: 146.8;Renal collecting duct intercalated cells: 106.3;Renal collecting duct principal cells: 78.1;Renal connecting tubule cells: 23.5" "Group enriched" "Detected in some" 5 "Ductal cells: 106.3;Renal nephron cells: 146.8" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in many" 17 "Testicular Germ Cell Tumor (TCGA): 400.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 19 "testis cancer: 264.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB025600, CAB026380, HPA058267, CAB079773" Approved Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 60: Stomach - Digestion" "Cluster 48: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 25 Nucleoplasm "Mitochondria, Cytosol" "CAB025600: , CAB026380: , CAB079773: , HPA058267: " "unprognostic (1.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.77e-1)" "unprognostic (4.58e-3)" "unprognostic (8.31e-2)" "unprognostic (1.43e-1)" "unprognostic (1.09e-2)" "unprognostic (8.94e-2)" "unprognostic (1.67e-1)" "unprognostic (8.64e-2)" "unprognostic (1.27e-1)" "unprognostic (3.94e-2)" "unprognostic (3.74e-2)" "unprognostic (7.49e-2)" "unprognostic (5.23e-2)" "unprognostic (2.69e-1)" "unprognostic (5.46e-2)" "unprognostic (1.72e-1)" "unprognostic (2.25e-2)" "unprognostic (1.00e-2)" "unprognostic (2.65e-2)" "unprognostic (2.01e-2)" "unprognostic (7.09e-2)" "unprognostic (4.52e-2)" "unprognostic (4.94e-2)" "unprognostic (4.58e-2)" "unprognostic (7.45e-2)" "unprognostic (2.13e-1)" POU5F1B "OTF3C, OTF3P1, POU5F1P1" ENSG00000212993 "POU class 5 homeobox 1B" Q06416 8 127322183-127420066 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 3.9" "Cell type enhanced" "Detected in some" "Breast lactating cells: 1.7;Choroid plexus epithelial cells: 3.3;Endometrial glandular cells: 1.6;Endometrial luminal cells: 2.6;Ependymal cells: 1.8;Parietal cells: 1.8;Respiratory ionocytes: 2.5" "Cell type enhanced" "Detected in some" "Ciliated cells: 3.3;Gastric glandular cells: 1.8;Glandular cells: 1.6;Ionocytes: 2.5;Luminal cells: 2.6;Secretory cells: 1.7" "Group enriched" "Detected in some" 11 "choroid plexus epithelial cell: 5.7;ependymal cell: 2.4" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 9.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enhanced" "Detected in single" "granulocytes: 1.3" "Cancer enhanced" "Detected in some" "colorectal cancer: 6.4" "Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA058267 Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 48: Non-specific - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" Nucleoplasm "Mitochondria, Cytosol" "HPA058267: " "unprognostic (2.60e-1)" "unprognostic (3.36e-3)" "unprognostic (1.23e-1)" "unprognostic (3.41e-1)" "potential prognostic favorable (3.01e-4)" "unprognostic (1.36e-1)" "potential prognostic favorable (8.29e-5)" "potential prognostic favorable (1.41e-6)" "unprognostic (1.17e-2)" "unprognostic (1.26e-1)" "unprognostic (1.11e-1)" "unprognostic (5.87e-1)" "unprognostic (8.05e-3)" "unprognostic (7.61e-2)" "unprognostic (6.72e-2)" "unprognostic (1.13e-2)" PPA2 FLJ20459 ENSG00000138777 "Inorganic pyrophosphatase 2" Q9H2U2 4 105369077-105474067 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Hydrolase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 152.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA030888, HPA031671, HPA031672" Supported Supported Mitochondria NA NA 85000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 10 Mitochondria "HPA030888: , HPA031671: , HPA031672: " "unprognostic (8.26e-2)" "unprognostic (1.49e-2)" "unprognostic (1.74e-2)" "unprognostic (2.39e-1)" "potential prognostic favorable (8.48e-4)" "unprognostic (2.62e-2)" "unprognostic (6.40e-2)" "unprognostic (5.35e-2)" "unprognostic (4.50e-2)" "unprognostic (9.00e-3)" "potential prognostic unfavorable (9.62e-4)" "unprognostic (2.93e-2)" "potential prognostic favorable (7.94e-5)" "unprognostic (1.35e-1)" "unprognostic (9.56e-2)" "unprognostic (3.04e-1)" "unprognostic (3.31e-2)" "unprognostic (2.35e-2)" "unprognostic (1.62e-2)" "unprognostic (8.87e-2)" "unprognostic (1.59e-2)" "unprognostic (2.38e-3)" "unprognostic (3.66e-1)" "unprognostic (1.22e-1)" "unprognostic (5.62e-2)" "unprognostic (2.11e-1)" "unprognostic (8.55e-2)" "unprognostic (9.71e-2)" "unprognostic (1.10e-2)" "unprognostic (3.57e-2)" "unprognostic (4.79e-2)" PPARA "hPPAR, NR1C1, PPAR" ENSG00000186951 "Peroxisome proliferator activated receptor alpha" Q07869 22 46150521-46243755 "FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Biological rhythms, Transcription, Transcription regulation" "Activator, DNA-binding, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 39.7" "Cell type enhanced" "Detected in many" "Enterocytes: 313.3;Hepatocytes: 326.6;Proximal tubule cells: 571.0;Rod photoreceptor cells: 680.1" "Cell type enhanced" "Detected in all" "Neuronal cells: 680.1;Renal nephron cells: 571.0" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 180.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 9.8;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 5 "dendritic cells: 2.9;granulocytes: 9.8" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15503 "Pancreas epithelial cells: 1550326.9" "Not detected" "Not detected" "HPA066941, CAB075701" Supported Uncertain "Nucleoli fibrillar center,Nuclear bodies,Primary cilium,Centriolar satellite,Basal body" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 76: Non-specific - Metabolism" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 79: Photoreceptor cells - Phototransduction" 38 "Primary cilium" "Nucleoli fibrillar center, Nuclear bodies, Centriolar satellite, Basal body" "CAB075701: , HPA066941: " "unprognostic (1.79e-2)" "unprognostic (4.00e-1)" "unprognostic (1.41e-1)" "unprognostic (5.67e-2)" "unprognostic (5.82e-2)" "unprognostic (5.52e-2)" "unprognostic (4.53e-3)" "unprognostic (4.96e-1)" "unprognostic (3.28e-2)" "unprognostic (2.48e-2)" "validated prognostic favorable (7.88e-8)" "validated prognostic favorable (1.63e-5)" "unprognostic (8.96e-3)" "unprognostic (1.25e-1)" "unprognostic (4.16e-3)" "unprognostic (7.48e-2)" "unprognostic (2.23e-1)" "unprognostic (2.52e-1)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (7.51e-2)" "unprognostic (2.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.16e-1)" "unprognostic (1.90e-3)" "unprognostic (3.39e-2)" "unprognostic (1.69e-1)" "unprognostic (6.15e-2)" "unprognostic (1.27e-1)" "unprognostic (3.87e-2)" "unprognostic (1.32e-1)" PPAT "GPAT, PRAT" ENSG00000128059 "Phosphoribosyl pyrophosphate amidotransferase" Q06203 4 56393362-56435615 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Purine biosynthesis" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 69.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 21290818.9" "Low tissue specificity" "Detected in many" "HPA036091, HPA036092" Approved Approved "Midbody ring" Yes No 7000 "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 9 "Midbody ring" "HPA036091: , HPA036092: " "unprognostic (4.62e-2)" "unprognostic (1.59e-2)" "unprognostic (1.41e-1)" "unprognostic (4.85e-2)" "unprognostic (8.12e-3)" "unprognostic (1.24e-2)" "unprognostic (2.32e-1)" "unprognostic (9.14e-2)" "unprognostic (9.22e-2)" "unprognostic (1.62e-3)" "potential prognostic favorable (7.37e-5)" "unprognostic (6.87e-2)" "unprognostic (2.94e-3)" "potential prognostic unfavorable (4.85e-9)" "unprognostic (1.69e-2)" "unprognostic (1.62e-3)" "potential prognostic unfavorable (5.06e-5)" "unprognostic (2.18e-1)" "unprognostic (1.45e-2)" "unprognostic (2.21e-1)" "unprognostic (7.94e-2)" "unprognostic (1.72e-3)" "unprognostic (5.56e-2)" "unprognostic (1.02e-1)" "unprognostic (4.55e-3)" "unprognostic (2.97e-1)" "unprognostic (5.16e-2)" "unprognostic (2.84e-1)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (9.58e-3)" PPCS FLJ11838 ENSG00000127125 "Phosphopantothenoylcysteine synthetase" Q9HAB8 1 42456117-42473385 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Ligase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 276.9;Megakaryocytes: 346.2;Parietal cells: 374.8" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 374.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA031361, HPA031363" Approved Approved Mitochondria NA NA 120000 "Cluster 25: Non-specific - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 4 Mitochondria "HPA031361: , HPA031363: " "unprognostic (1.08e-1)" "unprognostic (3.87e-1)" "unprognostic (1.14e-2)" "unprognostic (1.65e-1)" "unprognostic (3.92e-2)" "unprognostic (1.27e-1)" "unprognostic (3.46e-3)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (5.06e-3)" "unprognostic (4.37e-3)" "potential prognostic favorable (5.22e-5)" "unprognostic (8.90e-2)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (2.51e-2)" "unprognostic (9.13e-2)" "unprognostic (1.64e-1)" "unprognostic (4.40e-2)" "unprognostic (3.37e-3)" "unprognostic (4.92e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (2.91e-4)" "unprognostic (2.96e-1)" "unprognostic (4.90e-2)" "unprognostic (8.69e-2)" "unprognostic (6.54e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" "unprognostic (2.10e-1)" "unprognostic (2.61e-1)" PPDPF "C20orf149, dJ697K14.9, exdpf" ENSG00000125534 "Pancreatic progenitor cell differentiation and proliferation factor" Q9H3Y8 20 63520765-63522206 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 5 "Esophageal apical cells: 18164.9" "Cell type enriched" "Detected in many" 5 "Apical squamous epithelial cells: 18164.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "eosinophil: 26.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 26.0" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "cerebral cortex: 272476.9" HPA040929 Approved Nucleoplasm,Nucleoli,Microtubules Yes No "Cluster 19: Eosinophils - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 84: Apical squamous epithelium - Cornification" 5 "Nucleoplasm, Microtubules" Nucleoli "HPA040929: " "unprognostic (3.45e-3)" "unprognostic (1.57e-1)" "unprognostic (6.75e-2)" "unprognostic (8.61e-2)" "unprognostic (2.12e-1)" "unprognostic (1.21e-3)" "unprognostic (2.59e-2)" "unprognostic (2.26e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (2.85e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (5.21e-4)" "unprognostic (4.81e-2)" "unprognostic (1.98e-2)" "unprognostic (9.27e-2)" "unprognostic (1.62e-1)" "unprognostic (7.81e-3)" "unprognostic (2.27e-1)" "unprognostic (2.98e-1)" "unprognostic (3.01e-1)" "unprognostic (4.02e-2)" "unprognostic (5.55e-2)" "unprognostic (2.64e-1)" "unprognostic (4.71e-2)" "unprognostic (1.07e-1)" "unprognostic (1.10e-1)" "unprognostic (3.68e-2)" "unprognostic (5.66e-2)" "unprognostic (8.49e-2)" "unprognostic (2.20e-2)" PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 8.9;breast: 3.9;testis: 13.1" "Cell type enhanced" "Detected in many" "Early spermatids: 67.1;Late primary spermatocytes: 42.1;Late spermatids: 257.1;Neutrophil progenitors: 28.2;Sertoli cells: 19.9" "Cell type enriched" "Detected in many" 9 "Spermatogenic cell types: 257.1" "Cell type enhanced" "Detected in many" "miscellaneous: 36.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 5.4;Uterine cancer: 1.6" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18861 "Astrocytes and Neuropil: 2397219.2;Microglia and Neuropil: 2411311.2;Neurons: 849790.3" "Tissue enriched" "Detected in single" 1986 "cerebral cortex: 198559.1" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 67: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 1: Neuronal - Visual perception" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 5 "Plasma membrane" "Cytokinetic bridge" "HPA034577: " "unprognostic (8.78e-2)" "unprognostic (2.91e-2)" "potential prognostic unfavorable (2.88e-4)" "unprognostic (4.87e-2)" "unprognostic (3.72e-1)" "unprognostic (1.47e-1)" "unprognostic (7.69e-2)" "unprognostic (1.00e-1)" PPFIA1 "LIP.1, LIPRIN" ENSG00000131626 "PTPRF interacting protein alpha 1" Q13136 11 70270690-70385312 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 245.1;Bergmann glia: 208.6;Choroid plexus epithelial cells: 287.4;Distal convoluted tubule cells: 127.8;Early spermatids: 155.7;Microglia: 127.9;Proximal tubule cells: 138.7;Renal collecting duct intercalated cells: 145.9;Renal connecting tubule cells: 131.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 287.4;Ductal cells: 145.9;Glial cells: 245.1;Renal nephron cells: 138.7;Spermatogenic cell types: 155.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "intestine: 3777084.9" "CAB017032, HPA042271" Uncertain Supported "Focal adhesion sites,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 61 Cytosol "Focal adhesion sites" "CAB017032: , HPA042271: " "unprognostic (4.91e-1)" "unprognostic (6.85e-2)" "unprognostic (2.02e-2)" "unprognostic (8.93e-3)" "unprognostic (1.77e-1)" "unprognostic (1.04e-2)" "unprognostic (2.41e-1)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (3.31e-4)" "unprognostic (2.07e-1)" "potential prognostic favorable (9.74e-7)" "unprognostic (1.40e-1)" "unprognostic (2.07e-1)" "unprognostic (5.32e-2)" "unprognostic (1.27e-1)" "unprognostic (1.38e-2)" "unprognostic (2.24e-2)" "unprognostic (7.71e-2)" "unprognostic (2.25e-1)" "unprognostic (4.42e-3)" "unprognostic (2.41e-2)" "unprognostic (1.21e-3)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (1.10e-1)" "unprognostic (2.24e-3)" "unprognostic (1.80e-2)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (1.68e-1)" "unprognostic (1.66e-1)" "unprognostic (3.79e-3)" PPIB "B, CYP-S1, CYPB, OI9, PPIase, SCYLP" ENSG00000166794 "Peptidylprolyl isomerase B" P23284 15 64155740-64163134 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Isomerase, Rotamase" "Disease variant, Dwarfism, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1667.8;Extravillous trophoblasts: 2057.3;Plasma cells: 1608.1;Syncytiotrophoblasts: 1390.2" "Cell type enhanced" "Detected in all" "Trophoblast cells: 2057.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 781642625.4;Pancreatic islets: 867934460.9" "Low tissue specificity" "Detected in all" "CAB011487, HPA012720" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum" "Secreted to blood" Enzyme No No 27000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 45 "Endoplasmic reticulum" Nucleoplasm "CAB011487: , HPA012720: " "unprognostic (2.45e-1)" "unprognostic (1.05e-2)" "unprognostic (5.99e-2)" "unprognostic (7.70e-3)" "unprognostic (3.52e-1)" "unprognostic (1.06e-1)" "unprognostic (2.49e-2)" "unprognostic (1.31e-1)" "unprognostic (1.72e-3)" "unprognostic (2.48e-2)" "validated prognostic unfavorable (4.29e-4)" "validated prognostic unfavorable (8.14e-5)" "unprognostic (3.44e-2)" "unprognostic (1.13e-2)" "unprognostic (3.50e-3)" "unprognostic (3.82e-3)" "unprognostic (2.68e-2)" "unprognostic (7.14e-2)" "unprognostic (2.68e-3)" "unprognostic (3.92e-2)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (1.26e-1)" "unprognostic (1.28e-1)" "unprognostic (5.93e-2)" "unprognostic (1.77e-2)" "unprognostic (1.32e-1)" "unprognostic (1.67e-1)" "unprognostic (1.62e-1)" "unprognostic (6.11e-3)" PPID "CYP-40, CypD" ENSG00000171497 "Peptidylprolyl isomerase D" Q08752 4 158709127-158723396 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Protein transport, Transport" "Chaperone, Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA019520, HPA019692" Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Primary cilium,Cytosol" NA NA 4900 "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 17: Non-specific - RNA processing" 27 Cytosol "Nucleoplasm, Nucleoli, Nucleoli rim, Primary cilium" "HPA019520: , HPA019692: " "unprognostic (1.30e-2)" "unprognostic (1.01e-2)" "unprognostic (1.03e-1)" "unprognostic (2.47e-2)" "unprognostic (1.89e-1)" "unprognostic (8.09e-2)" "unprognostic (1.22e-2)" "unprognostic (9.39e-2)" "unprognostic (5.41e-3)" "unprognostic (2.43e-1)" "potential prognostic favorable (2.73e-4)" "unprognostic (3.57e-2)" "unprognostic (9.32e-2)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (4.26e-3)" "unprognostic (2.78e-1)" "unprognostic (4.08e-1)" "unprognostic (1.93e-1)" "unprognostic (1.34e-1)" "unprognostic (2.07e-1)" "unprognostic (4.02e-2)" "unprognostic (1.28e-2)" "unprognostic (4.90e-2)" "unprognostic (4.38e-3)" "unprognostic (1.85e-2)" "unprognostic (2.90e-2)" "unprognostic (2.56e-1)" "unprognostic (5.02e-1)" "unprognostic (5.04e-2)" "unprognostic (4.47e-3)" PPIG "CARS-Cyp, SCAF10, SRCyp" ENSG00000138398 "Peptidylprolyl isomerase G" Q13427 2 169584342-169641406 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 2043615.9" "Low tissue specificity" "Detected in many" "HPA021788, HPA057469" Supported Supported "Nuclear speckles,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 35 "Nuclear speckles" Cytosol "HPA021788: , HPA057469: " "unprognostic (1.02e-1)" "unprognostic (2.40e-1)" "unprognostic (2.60e-1)" "unprognostic (1.88e-1)" "unprognostic (2.95e-1)" "unprognostic (7.88e-2)" "unprognostic (1.13e-1)" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (3.24e-3)" "potential prognostic favorable (1.44e-5)" "unprognostic (1.75e-3)" "unprognostic (1.74e-2)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (2.61e-1)" "unprognostic (9.73e-2)" "unprognostic (2.30e-2)" "unprognostic (2.90e-2)" "unprognostic (5.25e-3)" "unprognostic (2.61e-2)" "unprognostic (3.99e-2)" "unprognostic (1.62e-2)" "unprognostic (2.34e-3)" "unprognostic (1.04e-1)" "unprognostic (7.75e-2)" "unprognostic (6.40e-2)" "unprognostic (7.67e-3)" "unprognostic (3.92e-2)" "unprognostic (3.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.93e-1)" PPIL1 CYPL1 ENSG00000137168 "Peptidylprolyl isomerase like 1" Q9Y3C6 6 36854827-36874803 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 71.2;Differentiating spermatogonia: 68.8;Extravillous trophoblasts: 74.5;Migrating cytotrophoblasts: 81.9;Oocytes: 87.5" "Cell type enhanced" "Detected in many" "Oocytes: 87.5;Trophoblast cells: 81.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2853796.2" "Low tissue specificity" "Detected in all" HPA062916 Supported Nucleoli NA NA 71000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 35: Non-specific - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 28: Non-specific - Nuclear processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 54 Nucleoli "HPA062916: " "unprognostic (1.36e-2)" "unprognostic (5.22e-3)" "unprognostic (1.44e-2)" "unprognostic (4.10e-2)" "unprognostic (4.05e-2)" "unprognostic (1.56e-1)" "unprognostic (1.32e-1)" "unprognostic (2.21e-1)" "unprognostic (1.36e-2)" "unprognostic (9.68e-2)" "potential prognostic favorable (5.03e-5)" "unprognostic (2.90e-2)" "unprognostic (4.74e-2)" "validated prognostic unfavorable (4.70e-8)" "validated prognostic unfavorable (6.14e-4)" "unprognostic (8.50e-3)" "unprognostic (1.98e-2)" "unprognostic (9.03e-2)" "unprognostic (3.76e-2)" "unprognostic (2.94e-3)" "unprognostic (3.45e-1)" "unprognostic (1.50e-2)" "unprognostic (4.00e-1)" "unprognostic (3.27e-2)" "unprognostic (2.86e-3)" "unprognostic (1.96e-1)" "unprognostic (7.07e-2)" "unprognostic (4.59e-2)" "unprognostic (1.94e-1)" "unprognostic (4.75e-2)" "unprognostic (4.80e-1)" PPIL2 "CYC4, Cyp-60, UBOX7" ENSG00000100023 "Peptidylprolyl isomerase like 2" Q13356 22 21666000-21700015 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" "intestine: 5710125.0;lymphoid tissue: 5511350.0" "HPA035344, HPA055637" Supported Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 13 Nucleoplasm "HPA035344: , HPA055637: " "unprognostic (1.44e-1)" "unprognostic (1.77e-3)" "unprognostic (2.22e-1)" "unprognostic (3.17e-1)" "unprognostic (2.33e-2)" "unprognostic (1.98e-1)" "unprognostic (1.98e-1)" "unprognostic (9.42e-2)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "potential prognostic favorable (5.52e-7)" "unprognostic (4.32e-3)" "unprognostic (2.13e-1)" "unprognostic (1.47e-2)" "unprognostic (8.25e-2)" "unprognostic (3.44e-2)" "unprognostic (2.87e-2)" "unprognostic (1.38e-1)" "unprognostic (3.77e-2)" "unprognostic (1.55e-1)" "unprognostic (1.33e-1)" "unprognostic (9.58e-2)" "unprognostic (7.84e-3)" "unprognostic (1.27e-1)" "unprognostic (8.36e-3)" "unprognostic (1.64e-1)" "unprognostic (2.95e-2)" "unprognostic (1.37e-1)" "unprognostic (2.70e-1)" "unprognostic (2.22e-1)" "unprognostic (2.01e-1)" PPIL3 CyPJ ENSG00000240344 "Peptidylprolyl isomerase like 3" Q9H2H8 2 200870907-200889303 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 140.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA040765, HPA062187" Approved Approved Nucleoplasm,Nucleoli NA NA 110000 "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 14 Nucleoplasm Nucleoli "HPA040765: , HPA062187: " "unprognostic (1.11e-1)" "unprognostic (1.67e-1)" "unprognostic (2.12e-1)" "unprognostic (8.06e-2)" "unprognostic (2.20e-1)" "unprognostic (1.65e-1)" "unprognostic (1.66e-1)" "unprognostic (2.17e-1)" "unprognostic (1.53e-1)" "unprognostic (4.64e-3)" "potential prognostic favorable (4.53e-4)" "unprognostic (8.18e-2)" "unprognostic (1.40e-1)" "unprognostic (2.28e-1)" "unprognostic (1.30e-1)" "unprognostic (2.07e-1)" "unprognostic (7.28e-2)" "unprognostic (3.73e-3)" "unprognostic (2.36e-1)" "unprognostic (2.88e-3)" "unprognostic (5.63e-2)" "unprognostic (2.06e-2)" "unprognostic (8.23e-2)" "unprognostic (1.65e-1)" "unprognostic (3.08e-2)" "unprognostic (2.30e-1)" "unprognostic (6.90e-2)" "unprognostic (2.43e-2)" "unprognostic (6.59e-2)" "unprognostic (5.59e-2)" "unprognostic (1.57e-1)" PPIP5K2 "CFAP160, DFNB100, HISPPD1, KIAA0433, VIP2" ENSG00000145725 "Diphosphoinositol pentakisphosphate kinase 2" O43314 5 103120149-103212799 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Hearing "Kinase, Transferase" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 288.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "intestine: 4445410.7" "HPA037895, HPA038442" Approved Approved Vesicles NA NA "Cluster 41: Basophils - Unknown function" "Cluster 15: Bone marrow - Innate immune response" "Cluster 37: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 Vesicles "HPA037895: , HPA038442: " "unprognostic (6.94e-3)" "unprognostic (9.10e-2)" "unprognostic (3.52e-2)" "unprognostic (3.27e-1)" "unprognostic (2.76e-1)" "unprognostic (1.26e-1)" "unprognostic (1.15e-1)" "unprognostic (6.51e-2)" "unprognostic (4.45e-2)" "potential prognostic unfavorable (9.27e-6)" "potential prognostic favorable (6.91e-5)" "unprognostic (4.92e-2)" "unprognostic (1.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.94e-1)" "unprognostic (1.98e-1)" "unprognostic (1.81e-1)" "unprognostic (1.66e-2)" "unprognostic (1.05e-1)" "unprognostic (4.59e-3)" "potential prognostic unfavorable (6.52e-5)" "unprognostic (2.42e-1)" "unprognostic (1.69e-2)" "unprognostic (9.22e-2)" "unprognostic (2.05e-3)" "unprognostic (2.01e-1)" "unprognostic (2.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (3.12e-4)" "unprognostic (1.73e-1)" PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 218.4;esophagus: 697.4;vagina: 274.1" "Cell type enriched" "Detected in many" 6 "Esophageal apical cells: 5894.4" "Cell type enriched" "Detected in many" 6 "Apical squamous epithelial cells: 5894.4" "Cell type enhanced" "Detected in many" "ependymal cell: 33.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 108.1" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Skeletal muscle - Macrophages, Skin - Keratinocyte (granular)" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting ducts: 677975281.5;Keratinocytes: 1899224842.1" "Tissue enhanced" "Detected in all" "lung: 926456677.4" "HPA042550, HPA059859" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Basal body,Cytosol" NA NA 190000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 65 "Plasma membrane, Basal body, Cytosol" Nucleoplasm "HPA042550: , HPA059859: " "unprognostic (4.79e-2)" "unprognostic (1.65e-1)" "unprognostic (1.87e-1)" "unprognostic (9.50e-2)" "unprognostic (8.80e-2)" "unprognostic (1.57e-1)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (6.81e-6)" "unprognostic (2.31e-1)" "unprognostic (2.52e-1)" "unprognostic (6.71e-2)" "unprognostic (1.34e-1)" "unprognostic (2.08e-2)" "unprognostic (7.10e-3)" "unprognostic (1.29e-2)" "unprognostic (1.26e-1)" "unprognostic (4.43e-2)" "unprognostic (2.75e-1)" "unprognostic (8.09e-2)" "potential prognostic unfavorable (5.28e-4)" "unprognostic (6.62e-2)" "unprognostic (4.55e-2)" "unprognostic (1.97e-3)" "unprognostic (2.52e-1)" "unprognostic (1.08e-2)" "unprognostic (3.68e-1)" "unprognostic (1.22e-1)" "unprognostic (3.52e-2)" "unprognostic (7.69e-2)" "unprognostic (8.53e-2)" "unprognostic (6.58e-2)" PPM1D "PP2C-DELTA, Wip1" ENSG00000170836 "Protein phosphatase, Mg2+/Mn2+ dependent 1D" O15297 17 60600193-60666280 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Hydrolase, Protein phosphatase" "Autism spectrum disorder, Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 140 "Granulosa cells: 20732.0;Macrophages: 12199.1;T-cells: 9028.5" "Not detected" "Not detected" "HPA022277, HPA061848" Approved Supported Nucleoplasm,Nucleoli NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 15 Nucleoplasm Nucleoli "HPA022277: , HPA061848: " "unprognostic (1.24e-3)" "unprognostic (1.11e-1)" "unprognostic (4.17e-1)" "unprognostic (2.87e-1)" "unprognostic (4.52e-2)" "unprognostic (2.95e-1)" "unprognostic (1.17e-1)" "unprognostic (6.68e-2)" "unprognostic (2.09e-2)" "unprognostic (6.56e-2)" "validated prognostic favorable (2.39e-5)" "validated prognostic favorable (5.04e-4)" "unprognostic (1.98e-1)" "unprognostic (4.22e-3)" "unprognostic (1.44e-2)" "unprognostic (1.95e-2)" "unprognostic (1.94e-1)" "unprognostic (1.61e-1)" "unprognostic (1.28e-3)" "unprognostic (3.84e-1)" "unprognostic (1.23e-1)" "potential prognostic favorable (4.88e-4)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.20e-4)" "unprognostic (3.32e-1)" "unprognostic (2.53e-3)" "unprognostic (1.42e-2)" "unprognostic (6.82e-2)" "unprognostic (2.95e-1)" "unprognostic (9.09e-2)" "unprognostic (1.62e-1)" PPM1E "CaMKP-N, KIAA1072, POPX1, PP2CH" ENSG00000175175 "Protein phosphatase, Mg2+/Mn2+ dependent 1E" Q8WY54 17 58755854-58985179 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "adrenal gland: 5.1;brain: 11.7;retina: 20.7;testis: 6.2" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 361.2;Brain excitatory neurons: 657.4;Brain inhibitory neurons: 265.9;Cone photoreceptor cells: 1397.3;Early primary spermatocytes: 438.3;Early spermatids: 257.8;Ependymal cells: 268.3;Gonadotrophs: 366.7;Other brain neurons: 400.7;Retinal bipolar cells: 550.2;Retinal horizontal cells: 1254.1;Rod photoreceptor cells: 386.7" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 361.2;Neuronal cells: 1397.3;Pituitary endocrine cells: 366.7;Spermatogenic cell types: 438.3" "Cell type enhanced" "Detected in all" "hippocampal CA4: 1649.8;hippocampal dentate gyrus: 2643.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 4.4;Prostate Adenocarcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 15.0;prostate cancer: 7.8" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 9925642.5;Microglia and Neuropil: 10495595.8;Neurons: 11291135.3" "Tissue enhanced" "Detected in some" "cerebral cortex: 5302533.4" "HPA018462, HPA019263" Approved Approved Nucleoplasm,Nucleoli Yes No "Cluster 32: Basophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" 4 Nucleoli Nucleoplasm "HPA018462: , HPA019263: " "unprognostic (1.41e-1)" "unprognostic (3.48e-1)" "potential prognostic favorable (5.93e-6)" "unprognostic (2.38e-1)" "potential prognostic favorable (3.16e-5)" "unprognostic (1.43e-1)" "unprognostic (4.71e-2)" PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919425-21952848 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lymphatic endothelial cells: 77.4;monocytes: 81.0;Neutrophils: 220.8" "Cell type enhanced" "Detected in all" "Neutrophils: 220.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 28.7" "Group enriched" "Detected in all" 7 "dendritic cells: 9.0;granulocytes: 28.7;monocytes: 24.6" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Oocytes: 317593116.2" "Low tissue specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" NA NA 390000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 1: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 9 Nucleoplasm "Plasma membrane" "HPA030989: , HPA030990: " "unprognostic (1.18e-1)" "unprognostic (1.29e-1)" "unprognostic (3.59e-2)" "unprognostic (1.79e-3)" "unprognostic (2.68e-1)" "unprognostic (3.23e-1)" "unprognostic (7.31e-2)" "unprognostic (2.19e-2)" "unprognostic (9.96e-2)" "unprognostic (2.33e-1)" "potential prognostic favorable (1.25e-5)" "unprognostic (1.10e-3)" "unprognostic (5.84e-2)" "unprognostic (5.80e-3)" "unprognostic (1.90e-1)" "unprognostic (1.24e-1)" "unprognostic (2.04e-1)" "unprognostic (1.50e-1)" "unprognostic (4.26e-2)" "unprognostic (4.13e-2)" "unprognostic (2.68e-2)" "unprognostic (1.52e-1)" "unprognostic (1.15e-2)" "unprognostic (3.74e-2)" "unprognostic (1.68e-2)" "potential prognostic favorable (6.36e-4)" "unprognostic (4.05e-2)" "unprognostic (1.91e-2)" "unprognostic (1.15e-1)" "unprognostic (6.73e-2)" "unprognostic (4.63e-1)" PPM1G "PP2CG, PP2Cgamma" ENSG00000115241 "Protein phosphatase, Mg2+/Mn2+ dependent 1G" O15355 2 27381195-27409591 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 232.2" "Group enriched" "Detected in all" 6 "Early spermatids: 1469.0;Late primary spermatocytes: 1906.4;Late spermatids: 5463.9" "Cell type enriched" "Detected in all" 18 "Spermatogenic cell types: 5463.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA035530, HPA035531" Enhanced Enhanced Nucleoplasm NA NA 30000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 108 Nucleoplasm "HPA035530: , HPA035531: " "unprognostic (2.59e-1)" "unprognostic (1.32e-1)" "unprognostic (3.65e-2)" "unprognostic (2.76e-3)" "unprognostic (3.25e-1)" "unprognostic (1.84e-1)" "unprognostic (1.39e-1)" "unprognostic (3.73e-2)" "unprognostic (6.97e-2)" "unprognostic (1.84e-3)" "unprognostic (6.41e-3)" "unprognostic (2.33e-2)" "unprognostic (6.11e-2)" "validated prognostic unfavorable (2.30e-7)" "validated prognostic unfavorable (6.08e-9)" "potential prognostic unfavorable (8.34e-5)" "unprognostic (1.55e-2)" "unprognostic (2.24e-2)" "unprognostic (1.60e-1)" "unprognostic (8.99e-3)" "unprognostic (6.99e-3)" "unprognostic (1.16e-2)" "unprognostic (4.86e-1)" "unprognostic (3.43e-3)" "unprognostic (3.95e-1)" "unprognostic (1.01e-1)" "unprognostic (1.54e-1)" "unprognostic (5.21e-2)" "unprognostic (1.36e-1)" "unprognostic (3.27e-1)" "unprognostic (3.08e-1)" PPM1J "DKFZp434P1514, FLJ35951, MGC19531, PP2Czeta, PPP2CZ" ENSG00000155367 "Protein phosphatase, Mg2+/Mn2+ dependent 1J" Q5JR12 1 112709994-112715332 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 71.0;testis: 66.1" "Group enriched" "Detected in some" 6 "Early spermatids: 87.2;Late spermatids: 258.5" "Cell type enriched" "Detected in some" 12 "Spermatogenic cell types: 258.5" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 18.4;ependymal cell: 27.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 74.5" "Lineage enriched" "Detected in many" 15 "dendritic cells: 74.5" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Keratinocyte (other), Testis - Late spermatids" "Region enriched" "Detected in many" 7 "olfactory bulb: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 846864.6;Microglia and Neuropil: 659374.8;Neurons: 821359.6" "Tissue enriched" "Detected in some" "cerebral cortex: 929022.9" HPA046045 Uncertain Approved Vesicles NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 4 Vesicles "HPA046045: " "unprognostic (2.31e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (2.45e-2)" "unprognostic (3.46e-2)" "unprognostic (9.89e-2)" "unprognostic (7.47e-3)" "unprognostic (2.29e-3)" "unprognostic (1.55e-2)" "unprognostic (2.24e-2)" "unprognostic (2.06e-1)" "unprognostic (1.14e-1)" "unprognostic (2.57e-1)" "unprognostic (3.77e-2)" "unprognostic (6.26e-3)" "unprognostic (1.30e-1)" "unprognostic (1.58e-1)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (7.18e-2)" "unprognostic (9.49e-2)" "unprognostic (4.50e-1)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" "potential prognostic favorable (5.53e-4)" "unprognostic (2.46e-1)" "unprognostic (5.42e-2)" "unprognostic (1.40e-1)" PPM1K "BDP, DKFZp761G058, hPTMP, PP2Ckappa, PP2Cm" ENSG00000163644 "Protein phosphatase, Mg2+/Mn2+ dependent 1K" Q8N3J5 4 88257620-88284769 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 86.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 275.1;Cardiomyocytes: 289.5;pDCs: 249.4;Sertoli cells: 204.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 40.9" "Heart muscle - Cardiomyocytes, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 4369610.7" "Tissue enhanced" "Detected in many" "heart muscle: 3526484.6" "HPA020066, HPA020862, HPA023891" Approved Supported Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 8 Mitochondria "HPA020066: , HPA020862: , HPA023891: " "unprognostic (3.52e-3)" "unprognostic (1.80e-1)" "unprognostic (1.43e-1)" "unprognostic (2.14e-1)" "unprognostic (3.79e-2)" "unprognostic (9.18e-2)" "unprognostic (2.52e-1)" "unprognostic (2.17e-1)" "unprognostic (1.81e-2)" "unprognostic (4.70e-2)" "unprognostic (5.88e-3)" "unprognostic (1.87e-2)" "unprognostic (1.41e-1)" "unprognostic (2.16e-1)" "unprognostic (2.17e-1)" "unprognostic (1.74e-2)" "unprognostic (1.66e-1)" "unprognostic (2.58e-2)" "unprognostic (3.04e-2)" "unprognostic (3.79e-2)" "unprognostic (6.95e-2)" "unprognostic (4.87e-3)" "unprognostic (1.69e-2)" "unprognostic (3.25e-2)" "unprognostic (7.93e-2)" "unprognostic (9.86e-2)" "unprognostic (1.99e-1)" "unprognostic (2.18e-2)" "unprognostic (1.62e-1)" "unprognostic (8.41e-2)" "unprognostic (4.43e-1)" PPME1 "ABDH19, PME-1" ENSG00000214517 "Protein phosphatase methylesterase 1" Q9Y570 11 74171267-74254703 "Enzymes, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 35735690.2" "CAB004541, HPA043900, HPA064396" Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA 52000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 72: Neuronal - Signal transduction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 38 Nucleoplasm "Nuclear bodies" "CAB004541: , HPA043900: , HPA064396: " "unprognostic (1.32e-1)" "unprognostic (1.21e-3)" "unprognostic (2.77e-1)" "unprognostic (9.08e-3)" "unprognostic (1.89e-1)" "unprognostic (1.66e-1)" "unprognostic (2.07e-1)" "unprognostic (2.17e-2)" "unprognostic (3.28e-2)" "unprognostic (3.15e-2)" "potential prognostic favorable (2.89e-5)" "unprognostic (4.17e-2)" "unprognostic (4.15e-1)" "unprognostic (1.55e-2)" "unprognostic (6.04e-3)" "unprognostic (4.20e-3)" "potential prognostic unfavorable (1.79e-4)" "unprognostic (9.24e-2)" "unprognostic (6.48e-2)" "unprognostic (3.41e-2)" "unprognostic (2.00e-2)" "unprognostic (1.34e-3)" "potential prognostic unfavorable (6.62e-5)" "unprognostic (6.93e-2)" "unprognostic (1.20e-1)" "unprognostic (7.68e-2)" "unprognostic (1.61e-1)" "unprognostic (5.71e-2)" "unprognostic (2.03e-1)" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" PPOX "PPO, VP" ENSG00000143224 "Protoporphyrinogen oxidase" P50336 1 161166056-161178013 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Heme biosynthesis, Porphyrin biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 77.9;Erythrocyte progenitors: 86.1;Fallopian tube ciliated cells: 92.4;Respiratory ciliated cells: 91.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 92.4;Erythrocytes: 86.1;Myocytes: 77.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fallopian tube cells: 35160499.4" "Tissue enhanced" "Detected in many" "fallopian tube: 28979021.6" HPA030123 Uncertain Approved Vesicles,Mitochondria,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 107: Ciliated cells - Cilia assembly & function" 27 Mitochondria "Vesicles, Cytosol" "HPA030123: " "unprognostic (1.60e-1)" "unprognostic (4.49e-1)" "unprognostic (1.20e-1)" "potential prognostic favorable (3.58e-4)" "unprognostic (6.91e-2)" "unprognostic (8.62e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.55e-4)" "unprognostic (1.06e-1)" "unprognostic (1.92e-1)" "unprognostic (3.30e-3)" "unprognostic (4.35e-2)" "unprognostic (1.93e-1)" "unprognostic (6.32e-3)" "unprognostic (3.84e-2)" "unprognostic (1.35e-2)" "unprognostic (3.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.62e-1)" "unprognostic (2.16e-2)" "unprognostic (6.43e-2)" "unprognostic (6.13e-3)" "unprognostic (2.49e-1)" "unprognostic (8.74e-2)" "unprognostic (2.78e-1)" "unprognostic (8.81e-2)" "unprognostic (7.19e-2)" "unprognostic (1.32e-1)" "unprognostic (2.78e-1)" "unprognostic (3.17e-2)" "unprognostic (4.92e-3)" PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398181-67421183 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 416.0;Esophageal apical cells: 821.4;Esophageal basal cells: 411.7;Esophageal suprabasal cells: 458.0;Extravillous trophoblasts: 647.2;Hofbauer cells: 400.6;Migrating cytotrophoblasts: 409.0;Syncytiotrophoblasts: 475.0" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 821.4;Trophoblast cells: 647.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol,Flagellar centriole,Mid piece,End piece" NA NA 2300000 "Cluster 25: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 293 "Nucleoplasm, Plasma membrane, Cytosol" "Flagellar centriole, Mid piece, End piece" "CAB004545: , HPA046833: " "unprognostic (1.45e-2)" "unprognostic (2.43e-1)" "unprognostic (4.63e-1)" "unprognostic (2.13e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (4.12e-2)" "unprognostic (2.13e-1)" "unprognostic (1.23e-2)" "unprognostic (2.74e-2)" "unprognostic (6.45e-3)" "unprognostic (1.14e-1)" "unprognostic (9.57e-2)" "unprognostic (1.08e-3)" "potential prognostic unfavorable (7.76e-5)" "unprognostic (9.86e-3)" "potential prognostic unfavorable (1.11e-5)" "unprognostic (2.45e-1)" "unprognostic (7.50e-2)" "unprognostic (7.51e-2)" "unprognostic (1.91e-1)" "unprognostic (3.98e-3)" "unprognostic (2.54e-1)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (5.85e-2)" "unprognostic (1.81e-1)" "unprognostic (2.42e-1)" "unprognostic (4.10e-2)" "unprognostic (4.02e-3)" "unprognostic (1.72e-1)" PPP1R15B FLJ14744 ENSG00000158615 "Protein phosphatase 1 regulatory subunit 15B" Q5SWA1 1 204396492-204411887 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Translation regulation" "Diabetes mellitus, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 110.6" "Cell type enhanced" "Detected in many" "monocytes: 255.9;Neutrophils: 420.6;Urothelial cells: 217.9" "Cell type enhanced" "Detected in many" "Neutrophils: 420.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 855 "Pancreas epithelial cells: 85517.3" "Not detected" "Not detected" HPA061088 Approved "Golgi apparatus" No No "Cluster 28: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 14 "Golgi apparatus" "HPA061088: " "unprognostic (8.24e-2)" "unprognostic (4.26e-2)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (1.48e-1)" "unprognostic (2.86e-1)" "unprognostic (2.67e-1)" "unprognostic (4.11e-2)" "unprognostic (1.85e-1)" "unprognostic (5.01e-3)" "potential prognostic favorable (3.03e-6)" "unprognostic (5.58e-2)" "unprognostic (1.29e-2)" "unprognostic (1.69e-1)" "unprognostic (4.43e-1)" "unprognostic (8.94e-3)" "unprognostic (4.32e-2)" "unprognostic (1.44e-1)" "unprognostic (2.26e-2)" "unprognostic (2.90e-1)" "unprognostic (4.40e-2)" "unprognostic (5.25e-2)" "unprognostic (9.60e-2)" "unprognostic (4.28e-2)" "unprognostic (1.50e-1)" "unprognostic (3.56e-1)" "unprognostic (2.34e-2)" "unprognostic (1.30e-1)" "unprognostic (2.47e-1)" "unprognostic (3.57e-3)" "unprognostic (2.70e-1)" PPP1R3E FLJ00089 ENSG00000235194 "Protein phosphatase 1 regulatory subunit 3E" Q9H7J1 14 23295652-23302859 "Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 43.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 72.7;Early spermatids: 105.4;Late spermatids: 59.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 72.7;Spermatogenic cell types: 105.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Spleen - B-cells (Spleen)" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 343418.3" "Tissue enhanced" "Detected in many" "ovary: 1813867.2" HPA061600 Approved Approved "Microtubules,Mitotic spindle,Mitochondria" Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 3 "Microtubules, Mitochondria" "Mitotic spindle" "HPA061600: " "unprognostic (2.59e-2)" "unprognostic (1.53e-2)" "unprognostic (3.68e-1)" "unprognostic (2.18e-2)" "potential prognostic unfavorable (1.54e-6)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (9.00e-2)" "potential prognostic favorable (2.31e-4)" "unprognostic (1.89e-1)" "unprognostic (1.56e-1)" "unprognostic (2.04e-2)" "unprognostic (3.70e-2)" "unprognostic (1.02e-1)" "unprognostic (8.90e-2)" "unprognostic (7.71e-3)" "unprognostic (1.07e-1)" "unprognostic (5.73e-3)" "unprognostic (7.23e-2)" "unprognostic (2.68e-1)" "unprognostic (5.75e-2)" "unprognostic (1.23e-3)" "unprognostic (2.03e-2)" "unprognostic (2.12e-1)" "unprognostic (1.52e-1)" "unprognostic (2.19e-1)" "unprognostic (1.62e-2)" "unprognostic (7.01e-2)" "unprognostic (9.57e-2)" "unprognostic (1.40e-1)" "unprognostic (1.83e-1)" PPP2R2A "B55A, B55alpha, PR52A, PR55A, PR55alpha" ENSG00000221914 "Protein phosphatase 2 regulatory subunit Balpha" P63151 8 26291508-26372680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 888.6;Neutrophils: 737.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 888.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA042122, HPA042770, CAB079289" Approved Approved Cytosol NA NA 18000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 67 Cytosol "CAB079289: , HPA042122: , HPA042770: " "unprognostic (1.94e-2)" "unprognostic (1.75e-1)" "unprognostic (1.57e-1)" "unprognostic (2.10e-1)" "unprognostic (9.47e-3)" "unprognostic (1.98e-1)" "unprognostic (1.00e-1)" "unprognostic (6.96e-2)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (3.01e-4)" "potential prognostic favorable (1.96e-9)" "unprognostic (2.73e-3)" "unprognostic (1.47e-1)" "unprognostic (4.60e-2)" "unprognostic (1.28e-1)" "unprognostic (1.47e-1)" "unprognostic (8.01e-2)" "unprognostic (1.31e-1)" "unprognostic (1.33e-1)" "unprognostic (5.70e-2)" "unprognostic (9.81e-3)" "unprognostic (4.22e-3)" "unprognostic (2.86e-3)" "unprognostic (6.44e-2)" "unprognostic (2.19e-2)" "unprognostic (1.75e-1)" "unprognostic (2.87e-1)" "unprognostic (2.88e-1)" "unprognostic (1.13e-1)" "unprognostic (1.21e-1)" "unprognostic (4.47e-2)" PPP2R2B "B55beta, PR52B, PR55-BETA, SCA12" ENSG00000156475 "Protein phosphatase 2 regulatory subunit Bbeta" Q00005 5 146580742-147084784 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Apoptosis "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 59.7;retina: 39.7;testis: 17.6" "Cell type enhanced" "Detected in many" "Astrocytes: 2900.2;Bergmann glia: 4881.4;Brain inhibitory neurons: 1044.9;Cone photoreceptor cells: 1455.3;Late spermatids: 1600.0;Oligodendrocyte progenitor cells: 1290.5;Oligodendrocytes: 6649.5;Pituitary stem cells: 3199.0;Rod photoreceptor cells: 1820.9;Schwann cells: 1176.7" "Cell type enhanced" "Detected in many" "Glial cells: 6649.5;Neuronal cells: 1820.9;Spermatogenic cell types: 1600.0;Stem cells: 3199.0" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 7526.3;oligodendrocyte: 6557.0" "Cancer enriched" "Detected in many" 10 "Glioblastoma Multiforme (TCGA): 46.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 5.2;MAIT T-cell: 4.1;memory CD4 T-cell: 2.4;memory CD8 T-cell: 6.2;naive CD8 T-cell: 3.8;NK-cell: 2.9;T-reg: 3.4" "Group enriched" "Detected in many" 9 "NK-cells: 2.9;T-cells: 6.2" "Cancer enhanced" "Detected in many" "cervical cancer: 6.2" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Microglia and Neuropil: 1611946.6" "Tissue enriched" "Detected in single" 3092 "cerebral cortex: 309209.0" "HPA038118, HPA042122, HPA042770" Approved Approved Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 33: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 41 Cytosol "HPA038118: , HPA042122: , HPA042770: " "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (3.27e-2)" "unprognostic (2.25e-1)" "unprognostic (6.41e-2)" "unprognostic (2.05e-2)" "unprognostic (4.69e-2)" "unprognostic (3.39e-1)" "unprognostic (2.39e-1)" "unprognostic (2.31e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (7.17e-6)" "unprognostic (6.61e-2)" "unprognostic (7.55e-2)" "unprognostic (7.69e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.75e-4)" "unprognostic (1.61e-1)" PPP2R2C "B55gamma, IMYPNO, MGC33570, PR52, PR55G" ENSG00000074211 "Protein phosphatase 2 regulatory subunit Bgamma" Q9Y2T4 4 6320578-6563600 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 112.0" "Cell type enhanced" "Detected in many" "Astrocytes: 97.4;Brain excitatory neurons: 200.1;Brain inhibitory neurons: 254.9;Corticotrophs: 98.6;Early spermatids: 108.1;Ependymal cells: 127.0;Esophageal apical cells: 337.9;Esophageal suprabasal cells: 104.6;Gonadotrophs: 120.9;Lactotrophs: 154.7;Late spermatids: 318.5;Ocular epithelial cells: 110.5;Other brain neurons: 140.7;Retinal ganglion cells: 208.6;Thyrotrophs: 127.6" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 337.9;Neuronal cells: 254.9;Pituitary endocrine cells: 154.7;Spermatogenic cell types: 318.5" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 35.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7708 "Astrocytes and Neuropil: 804063.7;Microglia and Neuropil: 540026.0;Neurons: 968190.0" "Tissue enriched" "Detected in single" 226585 "cerebral cortex: 22658464.9" "HPA042122, HPA042770, HPA060473" Approved Approved Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 35: Neurons - Synaptic function & neurogenesis" 24 Cytosol "HPA042122: , HPA042770: , HPA060473: " "unprognostic (7.46e-2)" "unprognostic (1.50e-2)" "unprognostic (4.69e-2)" "unprognostic (1.85e-2)" "unprognostic (4.81e-2)" "unprognostic (3.98e-2)" "unprognostic (5.40e-2)" "unprognostic (2.94e-2)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (5.52e-13)" "potential prognostic unfavorable (8.98e-4)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (8.00e-2)" "unprognostic (9.17e-3)" "unprognostic (1.34e-1)" "unprognostic (1.94e-2)" "unprognostic (3.59e-1)" "unprognostic (1.77e-1)" "unprognostic (7.66e-3)" "unprognostic (4.21e-2)" "unprognostic (6.44e-2)" "unprognostic (4.18e-1)" "unprognostic (1.26e-1)" "unprognostic (6.61e-2)" "unprognostic (1.01e-1)" "unprognostic (2.72e-1)" "unprognostic (3.70e-1)" "unprognostic (1.87e-2)" PPP2R2D "B55D, B55delta, MDS026" ENSG00000175470 "Protein phosphatase 2 regulatory subunit Bdelta" Q66LE6 10 131901008-131959834 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 15.0" "Cell type enhanced" "Detected in all" "Pancreatic acinar cells: 328.1;Somatotrophs: 332.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" "cerebral cortex: 898422.1;fallopian tube: 852913.7;heart muscle: 651236.6" "HPA042122, HPA042770" Approved Approved Cytosol NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 87 Cytosol "HPA042122: , HPA042770: " "unprognostic (6.28e-2)" "unprognostic (1.05e-1)" "unprognostic (5.02e-1)" "unprognostic (1.46e-1)" "unprognostic (8.35e-2)" "unprognostic (2.10e-1)" "potential prognostic favorable (6.34e-5)" "unprognostic (2.59e-1)" "unprognostic (4.12e-2)" "potential prognostic favorable (4.41e-4)" "unprognostic (1.30e-2)" "unprognostic (5.87e-3)" "unprognostic (3.88e-2)" "unprognostic (1.22e-1)" "unprognostic (3.32e-2)" "unprognostic (4.47e-3)" "unprognostic (2.80e-2)" "unprognostic (2.72e-1)" "unprognostic (1.45e-1)" "unprognostic (2.17e-1)" "unprognostic (1.14e-1)" "unprognostic (1.31e-1)" PPP2R3B "PPP2R3L, PPP2R3LY, PR48, PR70" ENSG00000167393 "Protein phosphatase 2 regulatory subunit B''beta" Q9Y5P8 X 333933-386955 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 59.2;skeletal muscle: 87.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 12.8;Early primary spermatocytes: 16.9;Loop of henle epithelial cells: 12.8;Oocytes: 32.2;Papillary tip epithelial cells: 12.9;Proximal tubule cells: 13.9;Renal collecting duct intercalated cells: 14.7;Renal collecting duct principal cells: 14.3;Renal connecting tubule cells: 15.8;Thymic myoid cells: 32.6;Undifferentiated spermatogonia: 12.4" "Cell type enhanced" "Detected in many" "Oocytes: 32.2;Stromal cells: 32.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6367 "Cardiomyocytes: 383772.4;Granulosa cells: 889569.3" "Tissue enriched" "Detected in single" 474 "Stomach: 47436.6" HPA026606 Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 105: Non-specific - Mixed function" 16 Nucleoplasm "Primary cilium, Primary cilium tip, Cytosol" "HPA026606: " "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-1)" "unprognostic (2.89e-2)" "unprognostic (5.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.10e-1)" "unprognostic (9.81e-2)" "unprognostic (1.15e-1)" "unprognostic (3.55e-2)" "unprognostic (4.36e-2)" "unprognostic (1.23e-1)" "unprognostic (8.79e-3)" "unprognostic (1.75e-1)" "unprognostic (3.70e-2)" "unprognostic (2.51e-1)" "unprognostic (7.59e-3)" "unprognostic (6.02e-3)" "unprognostic (2.29e-1)" "unprognostic (5.27e-2)" "unprognostic (1.10e-1)" PPP2R3C "C14orf10, FLJ20644, G4-1, G5PR" ENSG00000092020 "Protein phosphatase 2 regulatory subunit B''gamma" Q969Q6 14 35085467-35122517 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 467.0;Epicardial cells: 1244.0;Late primary spermatocytes: 615.6;Late spermatids: 286.4;Neutrophils: 387.8" "Group enriched" "Detected in all" 4 "Barrier epithelial cells: 1244.0;Neutrophils: 387.8;Spermatogenic cell types: 615.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1366485.5;Capillaries: 2191456.0" "Tissue enriched" "Detected in some" "lymphoid tissue: 70549.4" "HPA040835, HPA058834" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Actin filaments,Primary cilium,Cytosol" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 17 Nucleoplasm "Nuclear bodies, Golgi apparatus, Actin filaments, Primary cilium, Cytosol" "HPA040835: , HPA058834: " "unprognostic (3.57e-1)" "unprognostic (3.23e-2)" "unprognostic (7.11e-2)" "unprognostic (1.51e-2)" "unprognostic (2.62e-1)" "unprognostic (1.92e-1)" "unprognostic (1.72e-1)" "unprognostic (7.75e-2)" "unprognostic (2.28e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (9.43e-2)" "unprognostic (3.43e-3)" "unprognostic (3.27e-2)" "unprognostic (2.90e-1)" "unprognostic (3.61e-2)" "unprognostic (2.31e-1)" "unprognostic (5.96e-2)" "unprognostic (6.17e-2)" "unprognostic (1.33e-1)" "unprognostic (7.34e-2)" "unprognostic (4.29e-2)" "unprognostic (7.65e-2)" "unprognostic (2.17e-1)" "unprognostic (2.06e-1)" "unprognostic (4.48e-2)" "unprognostic (2.35e-1)" "unprognostic (1.36e-2)" "unprognostic (1.82e-2)" "unprognostic (6.56e-2)" PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 153.9;retina: 175.8" "Cell type enhanced" "Detected in many" "Early spermatids: 12.0;Late primary spermatocytes: 7.2;Megakaryocyte progenitors: 8.7;Megakaryocytes: 24.7;Platelets: 18.2;Rod photoreceptor cells: 8.1" "Cell type enhanced" "Detected in many" "Megakaryocytes: 24.7;Platelets: 18.2;Spermatogenic cell types: 12.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 106663539.8;Microglia and Neuropil: 86729664.7;Neurons: 55792782.0" "Tissue enriched" "Detected in all" "cerebral cortex: 315247005.5" "CAB005610, HPA047157" Approved Supported "Plasma membrane,Primary cilium,Cytosol" NA NA 53000 "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 47: Platelets - Hemostasis" 21 "Plasma membrane" "Primary cilium, Cytosol" "CAB005610: , HPA047157: " "unprognostic (2.60e-2)" "unprognostic (1.17e-2)" "unprognostic (2.40e-1)" "unprognostic (3.51e-2)" "unprognostic (1.14e-1)" "unprognostic (5.23e-3)" "unprognostic (2.84e-1)" "unprognostic (7.49e-3)" "unprognostic (2.20e-1)" "unprognostic (1.66e-3)" "potential prognostic favorable (2.48e-5)" "unprognostic (6.02e-2)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (6.85e-2)" "unprognostic (2.52e-2)" "unprognostic (1.35e-1)" "unprognostic (3.97e-2)" "unprognostic (1.43e-1)" "unprognostic (5.47e-2)" "unprognostic (7.72e-2)" "unprognostic (4.43e-2)" "potential prognostic unfavorable (6.20e-4)" "unprognostic (1.40e-2)" "unprognostic (9.26e-2)" "unprognostic (2.19e-1)" "unprognostic (3.13e-2)" "unprognostic (1.31e-1)" "unprognostic (1.01e-1)" "unprognostic (2.95e-1)" "unprognostic (7.52e-3)" "unprognostic (3.02e-1)" PPP3R2 PPP3RL ENSG00000188386 "Protein phosphatase 3 regulatory subunit B, beta" Q96LZ3 9 101591604-101595021 "FDA approved drug targets, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 619 "testis: 76.0" "Group enriched" "Detected in some" 8 "Early spermatids: 1.5;Late primary spermatocytes: 3.8;Late spermatids: 1.8" "Cell type enriched" "Detected in single" 13 "Spermatogenic cell types: 3.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047157 Uncertain Approved "Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 "Plasma membrane" "Primary cilium, Cytosol" "HPA047157: " PPP4R1 PP4R1 ENSG00000154845 "Protein phosphatase 4 regulatory subunit 1" Q8TF05 18 9546791-9615240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 395.3;Esophageal apical cells: 724.6;Neutrophils: 524.4;Urothelial cells: 351.2" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 724.6;Neutrophils: 524.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 36.2" "Lineage enriched" "Detected in all" 5 "granulocytes: 36.2" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA040905, HPA041089" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol,Perinuclear theca,Calyx,Mid piece,Principal piece,End piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "Plasma membrane, Cytosol" "Actin filaments, Perinuclear theca, Calyx, Mid piece, Principal piece, End piece" "HPA040905: , HPA041089: " "unprognostic (5.12e-2)" "unprognostic (3.55e-2)" "unprognostic (2.94e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-2)" "unprognostic (1.87e-3)" "unprognostic (9.19e-2)" "unprognostic (7.57e-3)" "unprognostic (2.21e-1)" "unprognostic (4.92e-2)" "potential prognostic favorable (1.23e-5)" "unprognostic (4.24e-3)" "unprognostic (2.05e-1)" "unprognostic (3.23e-3)" "unprognostic (1.04e-3)" "unprognostic (4.84e-2)" "unprognostic (1.87e-1)" "unprognostic (7.26e-2)" "unprognostic (2.41e-1)" "unprognostic (9.11e-2)" "unprognostic (7.64e-2)" "unprognostic (2.64e-2)" "unprognostic (1.05e-3)" "unprognostic (3.15e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-1)" "unprognostic (4.78e-2)" "unprognostic (3.93e-2)" "unprognostic (3.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.77e-1)" PPP6R1 "KIAA1115, SAP190, SAPS1" ENSG00000105063 "Protein phosphatase 6 regulatory subunit 1" Q9UPN7 19 55229779-55259017 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 236.7;Late primary spermatocytes: 87.6" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 236.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 28.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 14769165.6;T-cells: 15788095.4" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19289394.3" "HPA043989, HPA063681" Approved Enhanced Cytosol No No 6200 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 51: Neurons - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 50 Cytosol "HPA043989: , HPA063681: " "unprognostic (8.93e-2)" "unprognostic (3.15e-2)" "unprognostic (5.93e-3)" "unprognostic (3.35e-1)" "unprognostic (6.69e-2)" "unprognostic (2.77e-1)" "unprognostic (9.78e-2)" "unprognostic (1.65e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "unprognostic (1.16e-1)" "unprognostic (4.07e-1)" "potential prognostic unfavorable (6.84e-5)" "unprognostic (7.06e-2)" "unprognostic (3.35e-2)" "unprognostic (2.29e-1)" "unprognostic (9.97e-2)" "unprognostic (1.45e-1)" "unprognostic (1.04e-1)" "unprognostic (6.31e-2)" "unprognostic (6.26e-3)" "unprognostic (3.28e-1)" "unprognostic (9.21e-3)" "unprognostic (1.79e-1)" "unprognostic (2.94e-2)" "unprognostic (4.16e-1)" "unprognostic (1.25e-1)" "unprognostic (1.44e-1)" "unprognostic (1.07e-2)" "unprognostic (1.33e-1)" PPWD1 KIAA0073 ENSG00000113593 "Peptidylprolyl isomerase domain and WD repeat containing 1" Q96BP3 5 65563236-65587549 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 3624483.2" "Low tissue specificity" "Detected in many" "HPA019353, HPA019360" Enhanced Supported "Nuclear bodies" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 7: Non-specific - Transcription" 13 "Nuclear bodies" "HPA019353: , HPA019360: " "unprognostic (1.85e-2)" "unprognostic (2.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (9.28e-2)" "unprognostic (2.13e-1)" "unprognostic (2.21e-1)" "unprognostic (6.20e-2)" "unprognostic (1.69e-2)" "unprognostic (2.82e-2)" "unprognostic (4.36e-3)" "unprognostic (5.03e-2)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (3.52e-4)" "unprognostic (3.78e-2)" "unprognostic (7.90e-2)" "unprognostic (1.40e-1)" "unprognostic (2.24e-1)" "unprognostic (1.32e-1)" "unprognostic (4.90e-2)" "unprognostic (3.75e-2)" "unprognostic (8.80e-3)" "unprognostic (1.78e-2)" "unprognostic (4.90e-2)" "unprognostic (2.99e-3)" "unprognostic (1.64e-2)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (1.80e-1)" "unprognostic (1.50e-1)" "unprognostic (3.24e-2)" PQBP1 "MRX2, MRX55, MRXS3, MRXS8, RENS1, SHS" ENSG00000102103 "Polyglutamine binding protein 1" O60828 X 48890197-48903402 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity, mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA001880 Supported Supported "Nucleoplasm,Nuclear speckles,Microtubules,Primary cilium,Basal body,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 45: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 15: Non-specific - Protein processing" 31 "Nucleoplasm, Nuclear speckles, Primary cilium" "Microtubules, Basal body, Cytosol" "HPA001880: " "unprognostic (3.70e-1)" "unprognostic (8.43e-2)" "unprognostic (1.06e-1)" "unprognostic (1.73e-1)" "unprognostic (1.20e-1)" "unprognostic (3.39e-2)" "unprognostic (3.63e-2)" "potential prognostic favorable (6.70e-4)" "unprognostic (1.34e-2)" "unprognostic (1.92e-1)" "unprognostic (2.30e-3)" "unprognostic (1.36e-3)" "unprognostic (1.51e-2)" "unprognostic (2.14e-2)" "potential prognostic unfavorable (8.26e-4)" "unprognostic (1.93e-1)" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "unprognostic (5.93e-2)" "unprognostic (3.56e-2)" "unprognostic (7.54e-2)" "unprognostic (2.87e-1)" "unprognostic (3.42e-2)" "unprognostic (1.13e-1)" "unprognostic (6.17e-2)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (8.27e-2)" "unprognostic (2.40e-1)" "unprognostic (2.00e-1)" PRAME "CT130, MAPE" ENSG00000185686 "PRAME nuclear receptor transcriptional regulator" P78395 22 22547701-22559361 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Growth regulation, Transcription, Transcription regulation, Ubl conjugation pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 102.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 41.1;Early primary spermatocytes: 13.8;Endometrial ciliated cells: 2.9;Late primary spermatocytes: 3.6;Late spermatids: 4.7;Oocytes: 9.2;Sertoli cells: 4.0;Undifferentiated spermatogonia: 12.3" "Cell type enriched" "Detected in some" 4 "Spermatogenic cell types: 41.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 192.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 136.9" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Granulosa cells: 633212.5" "Not detected" "Not detected" "HPA045153, HPA068562, CAB080138" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 5: Rhabdoid - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 27 Nucleoplasm "Plasma membrane" "CAB080138: , HPA045153: , HPA068562: " "unprognostic (2.76e-3)" "unprognostic (5.22e-3)" "unprognostic (1.11e-1)" "unprognostic (1.39e-1)" "unprognostic (4.00e-2)" "unprognostic (2.34e-2)" "unprognostic (7.12e-2)" "unprognostic (2.05e-3)" "validated prognostic unfavorable (4.96e-7)" "validated prognostic unfavorable (5.60e-4)" "unprognostic (2.60e-1)" "unprognostic (2.32e-2)" "unprognostic (5.29e-3)" "unprognostic (1.28e-2)" "unprognostic (2.07e-1)" "unprognostic (2.42e-2)" "unprognostic (2.15e-2)" "unprognostic (4.45e-3)" "unprognostic (2.65e-2)" "unprognostic (8.39e-3)" "unprognostic (2.01e-1)" "unprognostic (1.70e-1)" "unprognostic (7.60e-2)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" "unprognostic (1.02e-2)" PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.5;testis: 50.4" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 25.7;Differentiating spermatogonia: 57.5;Early primary spermatocytes: 72.6;Early spermatids: 27.3;Enteric transient amplifying cells: 40.9;Erythrocyte progenitors: 80.7;Extravillous trophoblasts: 37.2;Gastric progenitor cells: 32.0;Late primary spermatocytes: 55.7;Megakaryocyte progenitors: 48.4;Migrating cytotrophoblasts: 30.4;Monocyte progenitors: 55.3;Oocytes: 55.3" "Cell type enhanced" "Detected in many" "Erythrocytes: 80.7;Megakaryocytes: 48.4;Mononuclear phagocytes: 55.3;Oocytes: 55.3;Spermatogenic cell types: 72.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Capillaries: 619906.8" "Tissue enriched" "Detected in single" 25408 "bone marrow: 2540760.5" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 35 "Microtubules, Cytokinetic bridge, Midbody" "Nucleoplasm, Plasma membrane" "HPA034521: , HPA048816: " "unprognostic (1.90e-1)" "unprognostic (7.46e-2)" "unprognostic (1.11e-1)" "unprognostic (1.36e-2)" "unprognostic (2.41e-1)" "unprognostic (4.15e-2)" "unprognostic (3.77e-1)" "potential prognostic favorable (5.62e-4)" "unprognostic (1.04e-1)" "unprognostic (2.40e-3)" "potential prognostic unfavorable (4.71e-9)" "unprognostic (1.47e-3)" "potential prognostic unfavorable (7.60e-9)" "validated prognostic unfavorable (7.19e-5)" "validated prognostic unfavorable (1.27e-7)" "validated prognostic unfavorable (3.40e-6)" "validated prognostic unfavorable (1.32e-4)" "unprognostic (2.24e-2)" "unprognostic (7.46e-2)" "unprognostic (2.82e-2)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (5.00e-5)" "unprognostic (3.85e-3)" "unprognostic (1.61e-2)" "unprognostic (2.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.75e-2)" "unprognostic (1.34e-1)" "unprognostic (3.21e-1)" "unprognostic (8.26e-2)" "unprognostic (3.25e-1)" PRDM10 "KIAA1231, MGC131802, PFM7" ENSG00000170325 "PR/SET domain 10" Q9NQV6 11 129899706-130002835 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 105.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Neurons: 271823.3;Neutrophils: 339015.1;Proximal tubules: 1085980.0;T-cells: 748263.5" "Group enriched" "Detected in many" "heart muscle: 300332.2;lymphoid tissue: 115971.5;salivary gland: 289483.3" "HPA026997, HPA061749" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Vesicles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Nucleoplasm "Nucleoli fibrillar center, Vesicles" "HPA026997: , HPA061749: " "unprognostic (2.55e-1)" "unprognostic (3.18e-2)" "unprognostic (5.08e-1)" "unprognostic (9.78e-3)" "unprognostic (2.94e-1)" "unprognostic (1.10e-1)" "unprognostic (6.94e-2)" "unprognostic (5.06e-3)" "unprognostic (1.02e-2)" "unprognostic (9.83e-2)" "validated prognostic favorable (7.99e-4)" "validated prognostic favorable (1.69e-4)" "unprognostic (1.47e-1)" "unprognostic (1.82e-2)" "unprognostic (2.23e-1)" "unprognostic (5.06e-2)" "unprognostic (7.96e-2)" "unprognostic (3.41e-1)" "unprognostic (3.58e-2)" "unprognostic (3.31e-2)" "unprognostic (5.97e-3)" "unprognostic (1.90e-2)" "unprognostic (6.68e-2)" "unprognostic (6.25e-2)" "unprognostic (5.14e-3)" "unprognostic (6.17e-3)" "unprognostic (2.69e-3)" "unprognostic (1.06e-1)" "unprognostic (2.75e-1)" "unprognostic (3.95e-2)" "unprognostic (1.46e-1)" PRDM13 PFM10 ENSG00000112238 "PR/SET domain 13" Q9H4Q3 6 99606774-99615578 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Cancer-related genes, Hypogonadotropic hypogonadism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.2;Oocytes: 9.2;Retinal amacrine cells: 2.8;Undifferentiated spermatogonia: 2.3" "Group enriched" "Detected in some" 18 "Neuronal cells: 2.8;Oocytes: 9.2;Spermatogenic cell types: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "hypothalamus: 1.2;medulla oblongata: 2.1;spinal cord: 1.4;white matter: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2364 "lymphoid tissue: 236379.7" "HPA046046, HPA062648, HPA069705, HPA070592" Uncertain Approved "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 22: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 41: Oocytes - Oogenesis" "Nucleoplasm, Nuclear speckles" Cytosol "HPA046046: , HPA062648: , HPA069705: , HPA070592: " "unprognostic (1.53e-1)" PRDM8 KMT8D ENSG00000152784 "PR/SET domain 8" Q9NQV8 4 80183879-80204329 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Neurogenesis, Transcription, Transcription regulation" "DNA-binding, Methyltransferase, Transferase" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 25.1;seminal vesicle: 25.6" "Cell type enriched" "Detected in many" 5 "Retinal bipolar cells: 285.4" "Cell type enriched" "Detected in many" 5 "Neuronal cells: 285.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 89.0;hippocampal CA4: 174.0" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Breast - Fibroblasts, Pituitary gland - Somatotropes, Stomach - Fibroblasts" "Region enhanced" "Detected in many" "hippocampal formation: 28.7" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1105 "Neurons: 110543.2" "Tissue enriched" "Detected in single" 180 "intestine: 17992.9" HPA057253 Supported "Nucleoplasm,Nuclear bodies" No NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nuclear bodies" Nucleoplasm "HPA057253: " "unprognostic (1.28e-2)" "unprognostic (2.63e-3)" "unprognostic (3.06e-2)" "unprognostic (1.20e-1)" "unprognostic (6.53e-2)" "unprognostic (1.85e-1)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (4.45e-4)" "unprognostic (1.44e-1)" "unprognostic (4.15e-2)" "unprognostic (5.75e-3)" "unprognostic (2.42e-1)" "unprognostic (7.25e-2)" "unprognostic (1.94e-1)" "unprognostic (2.34e-3)" "unprognostic (2.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.78e-2)" "unprognostic (1.74e-1)" PRDX3 "AOP-1, AOP1, MER5, SP-22" ENSG00000165672 "Peroxiredoxin 3" P30048 10 119167720-119178812 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "Corneal dystrophy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 371.8;Gastric progenitor cells: 352.5;Hepatocytes: 435.8;Migrating cytotrophoblasts: 346.7;Parietal cells: 611.7" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 611.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB008656, HPA041488, HPA063551, CAB079909" Enhanced Supported Vesicles,Mitochondria NA NA 2300000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 52: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 26 "Vesicles, Mitochondria" "CAB008656: , CAB079909: , HPA041488: , HPA063551: " "unprognostic (1.86e-1)" "unprognostic (1.40e-2)" "unprognostic (2.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.75e-2)" "unprognostic (2.43e-2)" "unprognostic (1.29e-1)" "unprognostic (8.11e-2)" "unprognostic (2.68e-3)" "unprognostic (1.11e-1)" "potential prognostic favorable (2.12e-8)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "potential prognostic favorable (8.70e-4)" "unprognostic (6.69e-2)" "unprognostic (2.51e-2)" "unprognostic (9.77e-2)" "unprognostic (1.99e-1)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (9.89e-4)" "unprognostic (2.47e-1)" "unprognostic (9.94e-2)" "unprognostic (3.04e-2)" "unprognostic (1.63e-1)" "unprognostic (6.64e-2)" "unprognostic (1.98e-1)" "unprognostic (1.44e-1)" "unprognostic (4.92e-1)" "unprognostic (2.14e-1)" PRDX5 "ACR1, AOEB166, B166, MGC117264, MGC142283, MGC142285, PLP, PMP20, PRDX6, PRXV, SBBI10" ENSG00000126432 "Peroxiredoxin 5" P30044 11 64318121-64321811 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Antioxidant, Oxidoreductase, Peroxidase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 1322.0" "Cell type enhanced" "Detected in all" "Enteric stem cells: 1543.6;Epididymal efferent duct ciliated cells: 2461.6;Esophageal apical cells: 4100.4;Esophageal suprabasal cells: 1925.4;Fallopian tube ciliated cells: 2319.4;Parietal cells: 1886.3;Respiratory ciliated cells: 2506.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 4100.4;Ciliated cells: 2506.5" "Cell type enhanced" "Detected in all" "ependymal cell: 214.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB008661, HPA037915, HPA037916" Enhanced Supported Mitochondria NA NA 6200000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 17 Mitochondria "CAB008661: , HPA037915: , HPA037916: " "unprognostic (1.73e-2)" "unprognostic (7.47e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-1)" "unprognostic (3.85e-1)" "unprognostic (1.25e-3)" "unprognostic (1.44e-1)" "unprognostic (2.42e-1)" "unprognostic (2.69e-2)" "unprognostic (2.84e-3)" "unprognostic (6.01e-2)" "unprognostic (1.61e-1)" "unprognostic (9.58e-3)" "validated prognostic unfavorable (9.83e-5)" "validated prognostic unfavorable (5.27e-5)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (2.97e-2)" "unprognostic (9.96e-2)" "potential prognostic favorable (1.75e-5)" "unprognostic (1.37e-1)" "unprognostic (2.08e-3)" "unprognostic (3.56e-1)" "unprognostic (5.12e-1)" "unprognostic (7.81e-2)" "unprognostic (1.12e-1)" "unprognostic (9.78e-2)" "unprognostic (1.94e-1)" "unprognostic (2.96e-1)" "unprognostic (4.83e-2)" "unprognostic (1.80e-1)" PRF1 "HPLH2, P1, PFP" ENSG00000180644 "Perforin 1" P14222 10 70597348-70602759 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Cytolysis "Cancer-related genes, Disease variant, Familial hemophagocytic lymphohistiocytosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 26.9;lung: 15.5;lymphoid tissue: 46.4" "Cell type enriched" "Detected in some" 5 "NK-cells: 737.8" "Cell type enriched" "Detected in some" 5 "NK-cells: 737.8" "Cell type enriched" "Detected in some" 233 "leukocyte: 262.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 900.8;MAIT T-cell: 628.8;memory CD8 T-cell: 498.2;naive CD8 T-cell: 313.2;NK-cell: 657.0" "Group enriched" "Detected in all" 50 "NK-cells: 657.0;T-cells: 900.8" "Cancer enriched" "Detected in some" 7 "lymphoma: 61.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Heart muscle - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Alveolar cell types: 9045919.6" "Group enriched" "Detected in many" "lung: 21365543.7;lymphoid tissue: 28405908.6" "CAB002436, HPA037940" Approved Approved Cytosol "Intracellular and membrane" Other NA NA 480000 "Cluster 15: NK-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 8: Immune cells - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 32 Cytosol "CAB002436: , HPA037940: " "unprognostic (6.99e-2)" "unprognostic (5.42e-3)" "unprognostic (4.69e-2)" "unprognostic (4.06e-2)" "unprognostic (1.01e-1)" "unprognostic (1.42e-1)" "unprognostic (3.46e-2)" "unprognostic (5.96e-2)" "potential prognostic favorable (4.55e-4)" "unprognostic (2.24e-1)" "unprognostic (2.60e-2)" "unprognostic (5.18e-2)" "unprognostic (7.16e-3)" "unprognostic (1.71e-2)" "unprognostic (4.57e-2)" "unprognostic (1.47e-1)" "unprognostic (9.53e-2)" "unprognostic (8.05e-2)" "unprognostic (1.95e-1)" "unprognostic (5.51e-3)" "unprognostic (3.49e-2)" "unprognostic (1.86e-1)" "unprognostic (7.95e-2)" "unprognostic (1.54e-1)" "unprognostic (1.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.55e-3)" "unprognostic (6.26e-2)" "unprognostic (2.88e-1)" "unprognostic (2.60e-2)" "unprognostic (1.79e-1)" PRICKLE1 "EPM1B, FLJ31937, RILP" ENSG00000139174 "Prickle planar cell polarity protein 1" Q96MT3 12 42456757-42590355 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 241.7;Brain inhibitory neurons: 174.7;Corticotrophs: 245.3;Endometrial stromal cells: 297.2;Fibro-adipogenic progenitors: 570.6;Oligodendrocyte progenitor cells: 209.0;Oligodendrocytes: 186.8;Retinal bipolar cells: 228.1;Retinal ganglion cells: 413.3;Salivary ionocytes: 174.8" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 570.6;Neuronal cells: 413.3;Stromal cells: 297.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.6" "Group enriched" "Detected in many" 4 "B-cells: 11.6;granulocytes: 4.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Testis - Early spermatids, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 759 "Microglia and Neuropil: 69785.2;Neurons: 82013.5" "Not detected" "Not detected" HPA001379 Approved Uncertain "Nucleoplasm,Basal body,Cytosol" NA NA "Cluster 18: Non-specific - Translation" "Cluster 13: Lung - Secretion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 4 Nucleoplasm "Basal body, Cytosol" "HPA001379: " "unprognostic (1.81e-1)" "unprognostic (1.71e-1)" "unprognostic (3.05e-1)" "unprognostic (8.03e-2)" "unprognostic (1.27e-2)" "unprognostic (7.30e-2)" "unprognostic (1.34e-1)" "unprognostic (3.37e-2)" "unprognostic (5.93e-2)" "unprognostic (9.90e-3)" "potential prognostic favorable (9.00e-4)" "unprognostic (3.89e-3)" "potential prognostic favorable (6.75e-4)" "unprognostic (9.24e-3)" "unprognostic (1.56e-2)" "unprognostic (2.03e-2)" "unprognostic (3.41e-2)" "unprognostic (8.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.13e-3)" "unprognostic (7.77e-2)" "unprognostic (9.91e-2)" "unprognostic (1.40e-1)" "unprognostic (5.53e-2)" "unprognostic (8.60e-3)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (1.10e-4)" "unprognostic (1.61e-1)" "unprognostic (8.10e-2)" "unprognostic (2.71e-1)" PRICKLE4 "C6orf49, DKFZp761H221, OEBT" ENSG00000278224 "Prickle planar cell polarity protein 4" Q2TBC4 6 41780782-41787452 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 1.4;Ependymal cells: 1.1" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.1;Glial cells: 1.4" "Cell type enriched" "Detected in some" 4 "endothelial cell: 5.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031240, HPA055593" Approved Approved "Mitotic spindle,Centriolar satellite" Yes NA "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 "Centriolar satellite" "Mitotic spindle" "HPA031240: , HPA055593: " "unprognostic (2.82e-3)" "unprognostic (1.33e-1)" "unprognostic (1.18e-3)" "unprognostic (1.36e-1)" "unprognostic (8.62e-2)" "potential prognostic favorable (1.41e-4)" "unprognostic (3.84e-2)" "unprognostic (4.36e-3)" "unprognostic (1.44e-1)" "unprognostic (8.44e-3)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.19e-1)" "unprognostic (5.54e-3)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (2.26e-1)" PRKAA1 AMPKa1 ENSG00000132356 "Protein kinase AMP-activated catalytic subunit alpha 1" Q13131 5 40759389-40798374 "Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Autophagy, Biological rhythms, Cholesterol biosynthesis, Cholesterol metabolism, Fatty acid biosynthesis, Fatty acid metabolism, Host-virus interaction, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism, Transcription, Transcription regulation, Wnt signaling pathway" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 276.6;Late primary spermatocytes: 263.0;Late spermatids: 707.5;Neutrophil progenitors: 279.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 707.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 76130536.0" "Low tissue specificity" "Detected in all" "CAB005050, HPA035409, HPA064946" Supported Supported "Nuclear speckles,Primary cilium,Basal body,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 45: Non-specific - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 90 "Nuclear speckles" "Primary cilium, Basal body, Cytosol" "CAB005050: , HPA035409: , HPA064946: " "unprognostic (1.57e-2)" "unprognostic (2.22e-1)" "unprognostic (1.87e-2)" "unprognostic (3.18e-3)" "unprognostic (2.10e-1)" "unprognostic (1.90e-3)" "unprognostic (1.61e-1)" "unprognostic (4.85e-2)" "unprognostic (1.38e-1)" "unprognostic (8.57e-3)" "potential prognostic favorable (1.15e-6)" "unprognostic (1.99e-2)" "unprognostic (2.05e-1)" "unprognostic (3.97e-2)" "unprognostic (1.34e-1)" "unprognostic (2.31e-1)" "unprognostic (1.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.75e-2)" "unprognostic (4.68e-2)" "potential prognostic unfavorable (6.73e-5)" "unprognostic (4.57e-3)" "unprognostic (1.47e-1)" "unprognostic (2.02e-1)" "unprognostic (1.04e-2)" "unprognostic (1.23e-1)" "unprognostic (6.38e-2)" "unprognostic (2.27e-1)" "unprognostic (2.46e-1)" "unprognostic (2.93e-2)" "unprognostic (3.12e-2)" PRKAB2 ENSG00000131791 "Protein kinase AMP-activated non-catalytic subunit beta 2" O43741 1 147155106-147172550 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 91.1;tongue: 97.0" "Cell type enhanced" "Detected in many" "Platelets: 101.7" "Cell type enhanced" "Detected in many" "Platelets: 101.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 14648587.2" "Group enriched" "Detected in many" "heart muscle: 5127505.2;liver: 8640428.0" HPA044342 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 37: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 1: Enterocytes - Absorption and Digestion" 221 Nucleoplasm Cytosol "HPA044342: " "unprognostic (5.31e-2)" "potential prognostic unfavorable (7.91e-4)" "unprognostic (5.21e-2)" "unprognostic (3.02e-2)" "unprognostic (7.53e-2)" "unprognostic (1.09e-2)" "unprognostic (9.12e-2)" "unprognostic (1.58e-2)" "unprognostic (4.30e-3)" "unprognostic (1.32e-2)" "unprognostic (3.76e-3)" "potential prognostic favorable (2.28e-4)" "unprognostic (2.25e-2)" "unprognostic (7.14e-2)" "unprognostic (2.75e-1)" "unprognostic (2.51e-2)" "unprognostic (8.69e-2)" "unprognostic (3.06e-1)" "unprognostic (2.25e-1)" "unprognostic (2.92e-2)" "unprognostic (2.13e-2)" "unprognostic (2.37e-1)" "unprognostic (1.31e-1)" "unprognostic (3.30e-1)" "unprognostic (1.60e-2)" "unprognostic (2.04e-1)" "unprognostic (3.60e-1)" "unprognostic (7.91e-2)" "unprognostic (4.09e-1)" "potential prognostic unfavorable (4.39e-4)" "unprognostic (6.47e-2)" PRKACA PKACa ENSG00000072062 "Protein kinase cAMP-activated catalytic subunit alpha" P17612 19 14091688-14118084 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cushing syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 276.2" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Bergmann glia: 25.2;Brain excitatory neurons: 34.9;Brain inhibitory neurons: 32.0;Choroid plexus epithelial cells: 18.6;Distal convoluted tubule cells: 21.8;Ependymal cells: 20.2;Loop of henle epithelial cells: 16.5;Microglia: 36.8;Oligodendrocyte progenitor cells: 21.7;Oligodendrocytes: 20.8;Other brain neurons: 42.7;Podocytes: 16.3;Proximal tubule cells: 17.2;Renal collecting duct intercalated cells: 18.7;Renal collecting duct principal cells: 18.9;Renal connecting tubule cells: 19.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 20.2;Ductal cells: 19.8;Glial cells: 36.8;Neuronal cells: 42.7;Renal nephron cells: 21.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 191445681.5" "Low tissue specificity" "Detected in all" "CAB010361, HPA071185" Approved Uncertain "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA 370000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 24: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 158 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Basal body" "CAB010361: , HPA071185: " "unprognostic (1.50e-2)" "unprognostic (6.82e-2)" "unprognostic (4.41e-2)" "unprognostic (3.96e-2)" "unprognostic (2.73e-1)" "unprognostic (4.54e-2)" "unprognostic (3.02e-2)" "unprognostic (2.00e-2)" "unprognostic (6.14e-2)" "unprognostic (1.30e-1)" "unprognostic (6.07e-2)" "unprognostic (1.17e-1)" "unprognostic (5.16e-2)" "unprognostic (3.18e-1)" "unprognostic (6.08e-2)" "unprognostic (1.39e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (8.02e-4)" "unprognostic (3.76e-1)" "unprognostic (2.41e-1)" "unprognostic (3.61e-2)" "potential prognostic favorable (9.59e-4)" "unprognostic (7.68e-2)" "unprognostic (2.50e-1)" "unprognostic (1.16e-2)" "unprognostic (1.15e-1)" "unprognostic (5.52e-2)" "unprognostic (2.70e-1)" "unprognostic (2.36e-2)" "unprognostic (6.54e-2)" "unprognostic (2.25e-1)" PRKACB PKACb ENSG00000142875 "Protein kinase cAMP-activated catalytic subunit beta" P22694 1 84078062-84238498 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 178.7" "Cell type enhanced" "Detected in all" "Brain inhibitory neurons: 439.1;Cone photoreceptor cells: 449.2;Corticotrophs: 416.4;Hematopoietic stem cells: 448.3;Megakaryocyte-Erythroid progenitors: 474.2;Oligodendrocytes: 493.4;Rod photoreceptor cells: 494.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 6972943.3;B-cells: 4512169.4;Microglia and Neuropil: 6137421.6;Neurons: 8413804.4;T-cells: 3002971.4" "Tissue enhanced" "Detected in all" "cerebral cortex: 6022077.1" "CAB010363, HPA029754, HPA071185" Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA 390000 "Cluster 1: T-cells - Unknown function" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 34 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Basal body" "CAB010363: , HPA029754: , HPA071185: " "unprognostic (2.87e-3)" "unprognostic (2.61e-1)" "unprognostic (3.41e-1)" "unprognostic (2.36e-2)" "unprognostic (1.04e-1)" "unprognostic (9.23e-2)" "unprognostic (8.89e-2)" "unprognostic (1.87e-1)" "unprognostic (1.86e-1)" "unprognostic (4.57e-2)" "potential prognostic favorable (8.82e-8)" "unprognostic (2.34e-3)" "unprognostic (4.79e-2)" "potential prognostic unfavorable (6.48e-5)" "unprognostic (9.70e-2)" "unprognostic (3.40e-2)" "unprognostic (2.40e-2)" "unprognostic (2.23e-1)" "unprognostic (4.68e-2)" "unprognostic (6.07e-2)" "unprognostic (8.26e-2)" "unprognostic (2.64e-1)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (1.80e-2)" "unprognostic (1.22e-1)" "unprognostic (6.87e-2)" "unprognostic (1.60e-1)" "unprognostic (8.47e-2)" "unprognostic (1.13e-2)" "unprognostic (7.55e-2)" PRKACG PKACg ENSG00000165059 "Protein kinase cAMP-activated catalytic subunit gamma" P22612 9 69012504-69014113 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 230 "testis: 23.0" "Group enriched" "Detected in some" 20 "Early spermatids: 72.1;Late primary spermatocytes: 119.3;Late spermatids: 119.7" "Cell type enriched" "Detected in single" 132 "Spermatogenic cell types: 119.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 12756869.9;Neurons: 6145885.5" "Tissue enriched" "Detected in some" "liver: 147070.1" "CAB004530, HPA071185" Supported Approved "Microtubules,Cytokinetic bridge,Primary cilium,Basal body,Cytosol" Yes NA "Cluster 23: Testis - Spermatogenesis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 20 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium, Basal body" "CAB004530: , HPA071185: " PRKAG1 ENSG00000181929 "Protein kinase AMP-activated non-catalytic subunit gamma 1" P54619 12 49002274-49018807 "FDA approved drug targets, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 30.1;Bergmann glia: 34.6;Brain excitatory neurons: 31.2;Brain inhibitory neurons: 31.4;Choroid plexus epithelial cells: 40.7;Distal convoluted tubule cells: 29.2;Ependymal cells: 24.3;Loop of henle epithelial cells: 26.3;Microglia: 34.9;Oligodendrocyte progenitor cells: 27.6;Oligodendrocytes: 30.3;Other brain neurons: 36.5;Papillary tip epithelial cells: 23.9;Podocytes: 32.0;Proximal tubule cells: 31.7;Renal collecting duct intercalated cells: 37.6;Renal collecting duct principal cells: 25.3;Renal connecting tubule cells: 25.6" "Group enriched" "Detected in many" 7 "Ciliated cells: 40.7;Ductal cells: 37.6;Glial cells: 34.9;Neuronal cells: 36.5;Renal nephron cells: 32.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA077805 Approved "Nucleoplasm,Nuclear bodies,Basal body,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 16: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" 49 "Nuclear bodies, Cytosol" "Nucleoplasm, Basal body" "HPA077805: " "unprognostic (1.36e-1)" "unprognostic (6.19e-3)" "unprognostic (1.38e-2)" "unprognostic (9.58e-3)" "unprognostic (1.01e-1)" "unprognostic (2.86e-1)" "unprognostic (2.16e-1)" "unprognostic (2.67e-1)" "unprognostic (6.75e-3)" "unprognostic (2.08e-2)" "potential prognostic favorable (2.47e-8)" "unprognostic (1.91e-1)" "unprognostic (6.83e-3)" "validated prognostic unfavorable (5.93e-7)" "validated prognostic unfavorable (5.40e-4)" "unprognostic (1.50e-2)" "unprognostic (1.63e-1)" "unprognostic (9.60e-2)" "unprognostic (2.72e-1)" "unprognostic (9.15e-2)" "unprognostic (5.53e-2)" "unprognostic (6.99e-2)" "unprognostic (1.21e-1)" "unprognostic (2.49e-1)" "unprognostic (2.39e-1)" "unprognostic (2.87e-2)" "unprognostic (5.71e-3)" "unprognostic (9.87e-2)" "unprognostic (4.34e-2)" "unprognostic (1.39e-1)" "unprognostic (7.84e-3)" PRKAR2A PRKAR2 ENSG00000114302 "Protein kinase cAMP-dependent type II regulatory subunit alpha" P13861 3 48744597-48847874 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 81.8;testis: 78.3" "Group enriched" "Detected in all" 4 "Early spermatids: 1048.8;Late spermatids: 1852.2" "Cell type enriched" "Detected in all" 5 "Spermatogenic cell types: 1852.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 154730494.3" "Low tissue specificity" "Detected in all" "CAB005023, HPA038268" Uncertain Uncertain "Vesicles,Centriolar satellite,Basal body,Cytosol,Mid piece" NA NA 72000 "Cluster 35: Neutrophils - Protein binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 71 "Centriolar satellite, Basal body, Mid piece" "Vesicles, Cytosol" "CAB005023: , HPA038268: " "unprognostic (5.18e-3)" "unprognostic (5.25e-2)" "unprognostic (5.95e-2)" "unprognostic (4.17e-3)" "unprognostic (4.49e-3)" "unprognostic (1.07e-1)" "unprognostic (2.31e-1)" "unprognostic (1.66e-2)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (2.54e-4)" "potential prognostic favorable (1.40e-5)" "unprognostic (6.56e-3)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (1.57e-1)" "unprognostic (3.43e-2)" "unprognostic (9.37e-2)" "unprognostic (1.34e-1)" "unprognostic (1.98e-1)" "unprognostic (2.44e-1)" "unprognostic (1.16e-2)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (1.36e-1)" "unprognostic (9.13e-3)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" "unprognostic (1.68e-1)" "unprognostic (3.94e-1)" "unprognostic (1.29e-2)" "unprognostic (1.76e-1)" PRKCA "PKCA, PKCalpha" ENSG00000154229 "Protein kinase C alpha" P17252 17 66302613-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.9" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 995.0;Astrocytes: 1157.1;Bergmann glia: 1773.9;Choroid plexus epithelial cells: 988.3;Oligodendrocyte progenitor cells: 1180.8;Renal connecting tubule cells: 967.4;Retinal bipolar cells: 1304.1" "Cell type enhanced" "Detected in all" "Glial cells: 1773.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 39128845.5" "Tissue enriched" "Detected in many" "cerebral cortex: 61908916.0" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 170000 "Cluster 11: T-cells - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 29: Forebrain - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 121 Cytosol "Vesicles, Plasma membrane" "CAB003844: , CAB016290: , HPA006563: , HPA006564: " "unprognostic (2.13e-2)" "unprognostic (5.59e-1)" "unprognostic (3.81e-2)" "potential prognostic unfavorable (3.97e-4)" "unprognostic (1.32e-1)" "unprognostic (7.67e-2)" "unprognostic (1.26e-1)" "unprognostic (3.98e-1)" "unprognostic (1.31e-2)" "unprognostic (2.33e-1)" "unprognostic (1.76e-1)" "unprognostic (1.99e-2)" "unprognostic (1.80e-1)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (3.50e-3)" "unprognostic (7.80e-2)" "unprognostic (3.38e-2)" "unprognostic (3.81e-2)" "unprognostic (8.91e-2)" "unprognostic (4.01e-1)" "unprognostic (1.77e-1)" "unprognostic (6.46e-3)" "unprognostic (7.15e-2)" "unprognostic (9.55e-2)" "unprognostic (2.61e-1)" "unprognostic (3.73e-2)" "unprognostic (2.50e-1)" "unprognostic (3.18e-1)" "unprognostic (4.68e-3)" "unprognostic (6.96e-3)" PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 396.1;Hematopoietic stem cells: 491.5;Innate lymphoid cells: 435.9;Lymphatic endothelial cells: 394.8;NK-cells: 1248.0;T-cells: 971.6;Vascular endothelial cells: 612.9" "Cell type enhanced" "Detected in all" "NK-cells: 1248.0;T-cells: 971.6" "Group enriched" "Detected in all" 6 "endothelial cell: 1433.4;leukocyte: 1439.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.2;MAIT T-cell: 91.4;memory CD4 T-cell: 88.5;memory CD8 T-cell: 136.2;naive CD4 T-cell: 107.8;naive CD8 T-cell: 104.9;NK-cell: 113.1;T-reg: 80.4" "Group enriched" "Detected in all" 13 "NK-cells: 113.1;T-cells: 136.2" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Stomach - Endothelial cells, Thyroid gland - Endothelial cells" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 5947660.9" "Group enriched" "Detected in some" 27242 "intestine: 1258016.3;lung: 3437291.0;lymphoid tissue: 4798132.8;salivary gland: 1403409.4" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: T-cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Cytosol "Plasma membrane" "HPA026294: , HPA053709: " "unprognostic (6.50e-2)" "unprognostic (4.26e-2)" "unprognostic (7.46e-2)" "unprognostic (9.39e-2)" "unprognostic (1.13e-1)" "unprognostic (2.75e-1)" "unprognostic (1.26e-1)" "unprognostic (4.00e-1)" "unprognostic (3.38e-3)" "unprognostic (9.30e-2)" "potential prognostic favorable (1.11e-6)" "unprognostic (1.71e-3)" "unprognostic (1.56e-1)" "unprognostic (2.38e-2)" "unprognostic (3.82e-3)" "unprognostic (9.72e-3)" "unprognostic (6.76e-3)" "unprognostic (1.85e-1)" "unprognostic (6.24e-2)" "unprognostic (2.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.32e-1)" "unprognostic (6.13e-3)" "unprognostic (8.13e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "unprognostic (6.96e-2)" "unprognostic (1.55e-1)" "unprognostic (1.04e-1)" PRKCI "DXS1179E, PKCI" ENSG00000163558 "Protein kinase C iota" P41743 3 170222424-170305977 "Cancer-related genes, Enzymes, FDA approved drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Podocytes: 382.8;Prostatic club cells: 360.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 4746865.5" "Low tissue specificity" "Detected in many" "HPA026574, HPA038635" Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 51: Secretory epithelial cells - Mixed function" 67 Cytosol "Microtubules, Cytokinetic bridge, Primary cilium" "HPA026574: , HPA038635: " "unprognostic (1.48e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-1)" "unprognostic (7.05e-2)" "unprognostic (9.27e-2)" "unprognostic (1.32e-2)" "unprognostic (2.10e-1)" "unprognostic (4.84e-2)" "unprognostic (3.61e-1)" "unprognostic (1.91e-2)" "potential prognostic favorable (3.65e-7)" "unprognostic (3.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.08e-2)" "unprognostic (1.57e-2)" "unprognostic (6.15e-2)" "unprognostic (2.64e-1)" "unprognostic (6.97e-2)" "unprognostic (1.82e-2)" "unprognostic (2.06e-1)" "potential prognostic unfavorable (7.92e-4)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.65e-1)" "unprognostic (3.97e-2)" "unprognostic (1.02e-2)" "unprognostic (1.25e-2)" "unprognostic (1.97e-1)" "unprognostic (4.50e-2)" "unprognostic (2.43e-1)" "unprognostic (3.45e-2)" "unprognostic (2.46e-1)" PRKCSH "G19P1, GIIB, PCLD, PLD1, VASAP-60" ENSG00000130175 "Protein kinase C substrate 80K-H" P14314 19 11435284-11450968 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 261.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004465, HPA041940, HPA043560" Supported Approved "Endoplasmic reticulum" "Intracellular and membrane" "No annotated function" NA NA 37000000 "Cluster 29: Non-specific - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 30: White matter - Myelination" "Cluster 23: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 33 "Endoplasmic reticulum" "CAB004465: , HPA041940: , HPA043560: " "unprognostic (2.68e-1)" "unprognostic (3.66e-2)" "unprognostic (1.73e-1)" "unprognostic (9.42e-3)" "unprognostic (3.68e-1)" "unprognostic (1.08e-1)" "unprognostic (7.08e-2)" "unprognostic (2.82e-3)" "unprognostic (7.79e-2)" "unprognostic (6.74e-3)" "unprognostic (7.10e-2)" "unprognostic (3.22e-2)" "unprognostic (6.28e-2)" "unprognostic (4.46e-2)" "potential prognostic unfavorable (2.39e-4)" "unprognostic (2.05e-3)" "unprognostic (1.86e-3)" "unprognostic (5.53e-2)" "unprognostic (2.14e-2)" "unprognostic (1.65e-2)" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.44e-1)" "unprognostic (1.70e-1)" "unprognostic (2.54e-3)" "unprognostic (1.86e-1)" "unprognostic (2.46e-1)" "unprognostic (1.97e-2)" "unprognostic (1.58e-1)" "unprognostic (7.33e-2)" "unprognostic (1.18e-1)" PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 137.3" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 483.6;Late spermatids: 1336.6;Syncytiotrophoblasts: 1824.2" "Group enriched" "Detected in many" 7 "Alveolar cells: 483.6;Spermatogenic cell types: 1336.6;Trophoblast cells: 1824.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 672635.0;Fallopian tube cells: 632839.3" "Tissue enriched" "Detected in some" "lung: 1160121.2" HPA021851 Enhanced Supported "Plasma membrane,Basal body,Cytosol,Flagellar centriole,Mid piece,End piece" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 105 Cytosol "Plasma membrane, Basal body, Flagellar centriole, Mid piece, End piece" "HPA021851: " "unprognostic (9.52e-2)" "unprognostic (1.90e-1)" "unprognostic (2.91e-1)" "unprognostic (6.19e-2)" "unprognostic (1.79e-2)" "unprognostic (9.42e-3)" "unprognostic (2.00e-1)" "potential prognostic favorable (3.35e-4)" "unprognostic (3.07e-1)" "unprognostic (8.30e-3)" "potential prognostic favorable (2.71e-10)" "unprognostic (6.89e-3)" "unprognostic (1.19e-2)" "unprognostic (2.72e-2)" "potential prognostic unfavorable (6.15e-4)" "unprognostic (7.94e-3)" "unprognostic (1.31e-1)" "unprognostic (1.30e-2)" "unprognostic (1.42e-1)" "unprognostic (4.49e-2)" "unprognostic (1.11e-1)" "unprognostic (5.04e-2)" "unprognostic (6.53e-2)" "unprognostic (1.86e-1)" "unprognostic (8.70e-2)" "unprognostic (5.65e-2)" "unprognostic (1.82e-2)" "unprognostic (1.01e-2)" "unprognostic (1.77e-1)" "unprognostic (3.25e-1)" "unprognostic (8.46e-2)" PRKD3 "EPK2, PRKCN" ENSG00000115825 "Protein kinase D3" O94806 2 37250502-37324833 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Melanocytes: 342.2;Rod photoreceptor cells: 285.2;Somatotrophs: 250.3" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "endothelial cell: 225.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 730501.5;T-cells: 249161.7" "Tissue enriched" "Detected in some" "lymphoid tissue: 1020198.6" HPA029529 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Basal body,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 44: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 4 "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles, Basal body" "HPA029529: " "unprognostic (1.68e-2)" "unprognostic (1.45e-1)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (7.31e-2)" "unprognostic (1.72e-2)" "unprognostic (6.10e-2)" "unprognostic (1.31e-1)" "unprognostic (6.72e-2)" "potential prognostic unfavorable (4.50e-6)" "unprognostic (1.10e-3)" "unprognostic (1.89e-1)" "unprognostic (1.40e-1)" "unprognostic (3.51e-3)" "unprognostic (3.91e-2)" "unprognostic (4.11e-2)" "unprognostic (1.94e-2)" "unprognostic (2.12e-1)" "unprognostic (2.93e-1)" "unprognostic (4.10e-1)" "unprognostic (4.13e-2)" "unprognostic (2.05e-1)" "unprognostic (1.20e-1)" "unprognostic (1.19e-1)" "unprognostic (4.57e-2)" "unprognostic (8.80e-2)" "unprognostic (1.00e-1)" "unprognostic (4.52e-2)" "unprognostic (4.28e-1)" "unprognostic (4.89e-2)" "unprognostic (4.31e-2)" PRKX PKX1 ENSG00000183943 "Protein kinase cAMP-dependent X-linked catalytic subunit" P51817 X 3604340-3713649 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 31.6" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 290.4;Endometrial glandular cells: 423.0;Endometrial luminal cells: 365.6;Innate lymphoid cells: 208.0;Loop of henle epithelial cells: 309.5;Mast cells: 658.3;NK-cells: 337.5" "Cell type enhanced" "Detected in many" "Glandular cells: 423.0;Mast cells: 658.3" "Cell type enhanced" "Detected in all" "leukocyte: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Endothelial cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 440946.3" "Tissue enriched" "Detected in single" 84 "lymphoid tissue: 8411.0" HPA015324 Supported Supported Nucleoplasm No No "Cluster 32: Basophils - Transcription" "Cluster 72: Kidney - Transmembrane transport" "Cluster 44: Non-specific - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 27 Nucleoplasm "HPA015324: " "unprognostic (4.36e-2)" "unprognostic (2.42e-1)" "unprognostic (6.32e-2)" "unprognostic (1.52e-1)" "unprognostic (2.45e-2)" "unprognostic (4.81e-2)" "unprognostic (1.23e-1)" "unprognostic (3.23e-3)" "unprognostic (1.54e-1)" "unprognostic (2.81e-1)" "potential prognostic favorable (2.50e-5)" "unprognostic (1.21e-3)" "unprognostic (8.18e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (6.87e-2)" "unprognostic (2.61e-1)" "unprognostic (2.52e-2)" "potential prognostic favorable (8.81e-4)" "unprognostic (4.10e-1)" "unprognostic (1.49e-1)" "unprognostic (2.17e-1)" "unprognostic (2.29e-1)" "unprognostic (1.12e-1)" "unprognostic (5.23e-2)" "unprognostic (1.10e-1)" "unprognostic (2.68e-1)" "unprognostic (2.26e-2)" "unprognostic (1.38e-1)" "unprognostic (2.08e-1)" "unprognostic (2.15e-1)" PRM1 CT94.1 ENSG00000175646 "Protamine 1" P04553 16 11280841-11281330 "Predicted intracellular proteins" "Differentiation, DNA condensation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 1247 "testis: 15140.1" "Cell type enriched" "Detected in some" 7 "Late spermatids: 1088815.8" "Cell type enriched" "Detected in some" 1310 "Spermatogenic cell types: 1088815.8" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 93 "Testicular Germ Cell Tumor (TCGA): 21.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055150, HPA059371" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 1 "Nucleoplasm, Cytosol" "HPA055150: , HPA059371: " "unprognostic (8.04e-2)" PRMT7 "FLJ10640, KIAA1933" ENSG00000132600 "Protein arginine methyltransferase 7" Q9NVM4 16 68310951-68360852 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 279.7;Myonuclei: 108.9" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 279.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 455002.1;Hepatocytes: 159342.9;Oocytes: 501763.7;T-cells: 337949.4" "Not detected" "Not detected" HPA044241 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 9 Nucleoplasm "Nucleoli fibrillar center" "HPA044241: " "unprognostic (4.48e-3)" "unprognostic (3.86e-2)" "unprognostic (1.51e-1)" "unprognostic (1.27e-2)" "unprognostic (1.96e-2)" "unprognostic (2.16e-1)" "unprognostic (1.17e-1)" "potential prognostic favorable (3.57e-4)" "unprognostic (8.24e-3)" "unprognostic (4.49e-2)" "unprognostic (4.12e-3)" "unprognostic (8.68e-2)" "unprognostic (1.41e-2)" "unprognostic (5.55e-2)" "unprognostic (1.11e-1)" "unprognostic (4.74e-1)" "unprognostic (1.94e-1)" "unprognostic (9.66e-2)" "unprognostic (3.49e-2)" "unprognostic (2.41e-1)" "unprognostic (3.52e-2)" "unprognostic (3.17e-2)" "unprognostic (1.36e-2)" "unprognostic (5.04e-2)" "unprognostic (7.03e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (7.29e-2)" "unprognostic (1.26e-2)" "unprognostic (6.89e-2)" "unprognostic (2.26e-1)" "unprognostic (2.19e-2)" PROX1 ENSG00000117707 "Prospero homeobox 1" Q92786 1 213983181-214041510 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 81.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 220.4;Corticotrophs: 213.2;Hepatocytes: 424.3;Lymphatic endothelial cells: 611.7;Myosatellite cells: 182.1;Pancreatic duct cells: 167.1;Respiratory ionocytes: 177.8;Retinal bipolar cells: 310.4;Retinal horizontal cells: 548.9;Tuft cells: 149.9" "Cell type enhanced" "Detected in many" "Endothelial cells: 611.7;Hepatocytes: 424.3;Neuronal cells: 548.9" "Cell type enhanced" "Detected in many" "CGE interneuron: 244.6;hippocampal dentate gyrus: 215.1;oligodendrocyte: 156.7" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 21.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 15.3;Neuroblastoma: 24.5" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Capillaries: 1033691.0;Hepatocytes: 468492.1" "Group enriched" "Detected in some" 1549 "liver: 180521.9;lymphoid tissue: 129180.7" "HPA000842, HPA001030, HPA027298" Enhanced Nucleoplasm,Cytosol No No "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 Nucleoplasm Cytosol "HPA000842: , HPA001030: , HPA027298: " "unprognostic (8.41e-2)" "unprognostic (2.95e-1)" "unprognostic (2.39e-2)" "unprognostic (2.31e-2)" "unprognostic (1.92e-2)" "unprognostic (2.10e-1)" "unprognostic (3.22e-1)" "unprognostic (3.13e-2)" "unprognostic (1.19e-2)" "unprognostic (9.53e-2)" "unprognostic (4.73e-1)" "unprognostic (2.54e-1)" "unprognostic (2.70e-1)" "unprognostic (2.88e-3)" "unprognostic (2.66e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (2.47e-2)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (8.82e-2)" PRPF6 "ANT-1, bB152O15.1, C20orf14, hPrp6, Prp6, RP60, SNRNP102, TOM, U5-102K" ENSG00000101161 "Pre-mRNA processing factor 6" O94906 20 63981132-64033100 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" HPA047106 Supported Supported "Nucleoplasm,Nuclear speckles,Vesicles,Centrosome,Basal body,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 17: Non-specific - RNA processing" 142 "Nucleoplasm, Nuclear speckles, Basal body" "Vesicles, Centrosome, Cytosol" "HPA047106: " "unprognostic (8.07e-2)" "unprognostic (1.43e-1)" "unprognostic (1.77e-1)" "unprognostic (5.63e-2)" "unprognostic (2.49e-1)" "unprognostic (3.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.10e-1)" "unprognostic (7.99e-2)" "unprognostic (4.67e-3)" "potential prognostic favorable (4.07e-5)" "unprognostic (5.30e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (3.16e-4)" "unprognostic (9.04e-3)" "unprognostic (6.93e-2)" "unprognostic (8.75e-2)" "unprognostic (1.59e-1)" "unprognostic (7.90e-2)" "unprognostic (4.92e-2)" "unprognostic (7.43e-2)" "unprognostic (1.71e-3)" "unprognostic (2.51e-2)" "unprognostic (8.10e-2)" "unprognostic (2.09e-2)" "unprognostic (6.28e-3)" "unprognostic (1.25e-1)" "unprognostic (5.15e-2)" "unprognostic (4.48e-1)" "unprognostic (7.66e-2)" "unprognostic (2.55e-1)" PRPS2 ENSG00000101911 "Phosphoribosyl pyrophosphate synthetase 2" P11908 X 12791355-12824222 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 141.8;parathyroid gland: 171.4" "Cell type enhanced" "Detected in many" "Breast lactating cells: 286.2;Decidual stromal cells: 521.1;Leydig cells: 1809.4;Parietal cells: 341.2;Peritubular myoid cells: 2294.5" "Group enriched" "Detected in many" 6 "Leydig cells: 1809.4;Stromal cells: 2294.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA051269, HPA067599, CAB070417" Enhanced Approved "Nuclear speckles,Vesicles,Basal body" NA NA 370000 "Cluster 18: Non-specific - Translation" "Cluster 61: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 36: Non-specific - mRNA processing" "Cluster 94: Gonadal somatic cells - Mixed function" 28 Vesicles "Nuclear speckles, Basal body" "CAB070417: , HPA051269: , HPA067599: " "unprognostic (5.52e-3)" "unprognostic (2.57e-1)" "unprognostic (3.09e-1)" "unprognostic (3.31e-2)" "unprognostic (8.06e-3)" "unprognostic (3.23e-1)" "unprognostic (5.18e-2)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (3.42e-3)" "unprognostic (2.67e-2)" "potential prognostic favorable (1.17e-6)" "unprognostic (2.83e-1)" "unprognostic (4.42e-2)" "unprognostic (1.35e-2)" "unprognostic (2.54e-3)" "unprognostic (2.70e-2)" "unprognostic (4.70e-3)" "unprognostic (7.94e-2)" "unprognostic (7.34e-2)" "unprognostic (5.37e-2)" "unprognostic (8.61e-2)" "unprognostic (4.31e-3)" "unprognostic (3.75e-1)" "unprognostic (5.70e-2)" "unprognostic (2.76e-2)" "unprognostic (9.72e-3)" "unprognostic (1.20e-2)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (2.36e-1)" PRR11 FLJ11029 ENSG00000068489 "Proline rich 11" Q96HE9 17 59155732-59206709 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 17.0;lymphoid tissue: 19.1" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 26.3;Extravillous trophoblasts: 12.2;Hematopoietic stem cells: 34.9;Megakaryocyte progenitors: 40.5;Megakaryocyte-Erythroid progenitors: 24.7;Monocyte progenitors: 44.0;Neutrophil progenitors: 17.3" "Cell type enhanced" "Detected in many" "Erythrocytes: 26.3;Megakaryocytes: 40.5;Mononuclear phagocytes: 44.0;Stem cells: 34.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 13.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 9.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 32 "Granulosa cells: 3150.7" "Not detected" "Not detected" "HPA023923, HPA052376" Uncertain Approved "Endoplasmic reticulum" Yes Yes "Cluster 25: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 4 "Endoplasmic reticulum" "HPA023923: , HPA052376: " "unprognostic (2.42e-1)" "unprognostic (2.68e-2)" "unprognostic (2.22e-1)" "unprognostic (6.41e-3)" "unprognostic (9.33e-2)" "unprognostic (8.61e-2)" "unprognostic (1.94e-1)" "unprognostic (2.20e-1)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (5.78e-5)" "potential prognostic unfavorable (5.86e-5)" "unprognostic (1.39e-2)" "potential prognostic unfavorable (8.25e-6)" "validated prognostic unfavorable (3.80e-7)" "validated prognostic unfavorable (1.25e-7)" "potential prognostic unfavorable (7.56e-6)" "unprognostic (1.09e-3)" "unprognostic (8.30e-3)" "unprognostic (3.53e-1)" "unprognostic (2.11e-1)" "unprognostic (4.74e-1)" "unprognostic (1.30e-3)" "unprognostic (2.30e-3)" "unprognostic (2.38e-1)" "unprognostic (9.30e-2)" "unprognostic (1.54e-2)" "unprognostic (4.48e-3)" "unprognostic (9.41e-2)" "unprognostic (1.18e-1)" "unprognostic (1.07e-2)" "unprognostic (9.37e-2)" PRR15L "ATAD4, MGC11242" ENSG00000167183 "Proline rich 15 like" Q9BU68 17 47951967-47957883 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 167.7;pancreas: 99.0;stomach 1: 80.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 96.0;Cholangiocytes: 78.7;Colonocytes: 188.2;Enteric stem cells: 105.7;Enteric transient amplifying cells: 104.7;Enterocytes: 242.7;Gastric chief cells: 67.7;Goblet cells: 120.2;Paneth cells: 89.0;Parietal cells: 132.6;Salivary duct cells: 81.9" "Cell type enhanced" "Detected in many" "Enterocytes: 242.7;Gastric glandular cells: 132.6;Goblet cells: 120.2" "Cell type enriched" "Detected in single" 4 "choroid plexus epithelial cell: 3.6" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 8 "choroid plexus: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 50.6;colorectal cancer: 47.9;Gastric cancer: 39.1" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes, Skin - Eccrine sweat gland cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 15.9" "Cell type enhanced" "Detected in some" "Distal tubules: 94716.0;Large ducts: 41457.9" "Tissue enriched" "Detected in single" 131 "lung: 13071.0" HPA022918 Approved Approved Cytosol No NA "Cluster 60: Stomach - Digestion" "Cluster 36: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" Cytosol "HPA022918: " "unprognostic (1.08e-1)" "unprognostic (1.92e-2)" "unprognostic (7.44e-2)" "unprognostic (1.49e-1)" "unprognostic (9.32e-2)" "unprognostic (8.52e-3)" "unprognostic (5.54e-2)" "unprognostic (1.85e-1)" "potential prognostic favorable (2.11e-5)" "unprognostic (1.39e-2)" "potential prognostic favorable (6.68e-4)" "unprognostic (2.76e-1)" "unprognostic (4.48e-3)" "unprognostic (1.07e-1)" "unprognostic (7.52e-2)" "unprognostic (1.08e-2)" "unprognostic (1.45e-1)" "unprognostic (9.83e-2)" "unprognostic (3.96e-2)" "unprognostic (4.54e-2)" "unprognostic (1.54e-3)" "unprognostic (3.12e-1)" "unprognostic (1.05e-1)" "unprognostic (6.70e-2)" "potential prognostic favorable (1.49e-4)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (2.88e-2)" PRR16 DSC54 ENSG00000184838 "Proline rich 16" Q569H4 5 120464300-120687332 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 28.3" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 160.5;Brain excitatory neurons: 250.4;Brain inhibitory neurons: 247.9;Cardiomyocytes: 172.6;Cone photoreceptor cells: 569.3;Endometrial stromal cells: 352.0;Fibroblasts: 144.6;Hematopoietic stem cells: 246.5;Myonuclei: 413.2;Other brain neurons: 194.3;Pericytes: 163.9;Retinal bipolar cells: 171.8;Retinal horizontal cells: 156.3;Somatotrophs: 199.7;Thymic myoid cells: 376.6" "Cell type enhanced" "Detected in many" "Myocytes: 413.2;Neuronal cells: 569.3;Stem cells: 246.5;Stromal cells: 376.6" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 769.9" "Cancer enriched" "Detected in many" 6 "Prostate Adenocarcinoma (TCGA): 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA049254 Approved Approved Nucleoplasm,Midbody,Cytosol Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 5 Nucleoplasm "Midbody, Cytosol" "HPA049254: " "unprognostic (4.32e-1)" "unprognostic (8.28e-2)" "unprognostic (1.80e-1)" "unprognostic (1.79e-1)" "unprognostic (1.74e-1)" "unprognostic (1.26e-1)" "unprognostic (4.78e-1)" "unprognostic (3.43e-3)" "unprognostic (8.58e-2)" "unprognostic (2.63e-1)" "unprognostic (6.98e-2)" "unprognostic (3.88e-2)" "unprognostic (9.59e-3)" "unprognostic (3.02e-3)" "unprognostic (1.01e-1)" "unprognostic (7.27e-2)" "unprognostic (3.98e-2)" "unprognostic (3.83e-2)" "unprognostic (2.83e-2)" "unprognostic (1.90e-1)" "unprognostic (2.09e-1)" "unprognostic (5.33e-2)" "unprognostic (9.40e-2)" "unprognostic (9.60e-3)" "unprognostic (3.81e-2)" "unprognostic (2.76e-2)" PRR19 MGC70924 ENSG00000188368 "Proline rich 19" A6NJB7 19 42302098-42310814 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 20.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 29.3;Early primary spermatocytes: 31.2;Early spermatids: 27.6;Late primary spermatocytes: 39.6;Late spermatids: 102.4" "Cell type enriched" "Detected in many" 8 "Spermatogenic cell types: 102.4" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA070350 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Mitochondria" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 "Nucleoli, Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA070350: " "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.15e-2)" "unprognostic (1.98e-2)" "unprognostic (5.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.73e-1)" "unprognostic (1.77e-1)" "unprognostic (6.66e-3)" "unprognostic (5.96e-2)" "unprognostic (3.17e-2)" "validated prognostic unfavorable (1.46e-4)" "validated prognostic unfavorable (3.43e-5)" "unprognostic (9.61e-3)" "unprognostic (3.98e-3)" "unprognostic (1.00e-3)" "unprognostic (1.30e-1)" "unprognostic (3.75e-2)" "unprognostic (2.56e-3)" "unprognostic (1.03e-1)" "unprognostic (8.41e-2)" "unprognostic (1.70e-1)" "unprognostic (3.59e-2)" "unprognostic (1.32e-1)" "unprognostic (1.26e-1)" "unprognostic (1.03e-1)" "unprognostic (3.44e-1)" PRR23A ENSG00000206260 "Proline rich 23A" A6NEV1 3 139003962-139006268 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in single" 14 "testis: 2.1" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 9.8;Early primary spermatocytes: 29.7;Early spermatids: 2.4;Late primary spermatocytes: 3.8;Oocytes: 18.4;Undifferentiated spermatogonia: 5.5" "Group enriched" "Detected in some" 232 "Oocytes: 18.4;Spermatogenic cell types: 29.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA047473 Uncertain Approved "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 3: Early primary spermatocytes - Early meiosis" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: " "unprognostic (3.42e-1)" PRR23B FLJ46116 ENSG00000184814 "Proline rich 23B" Q6ZRT6 3 139019031-139020926 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 1.2" "Group enriched" "Detected in some" 18 "Differentiating spermatogonia: 4.1;Early primary spermatocytes: 7.7" "Cell type enriched" "Detected in single" 76 "Spermatogenic cell types: 7.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA047473 Uncertain Uncertain "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 23: Testis - Spermatogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: " PRR23C FLJ46210 ENSG00000233701 "Proline rich 23C" Q6ZRP0 3 139042102-139044892 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 3.8;Early primary spermatocytes: 3.0;Early spermatids: 3.7;Late spermatids: 4.5" "Cell type enriched" "Detected in single" 45 "Spermatogenic cell types: 4.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.0" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA047473 Uncertain Approved "Nucleoplasm,Nuclear bodies,Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 48: Non-specific - Mixed function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Nucleoplasm, Microtubules" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA047473: " PRR35 C16orf11 ENSG00000161992 "Proline rich 35" P0CG20 16 560394-565529 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 137.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 17.9;Renal collecting duct intercalated cells: 4.0;Renal collecting duct principal cells: 15.8;Renal connecting tubule cells: 21.0;Retinal amacrine cells: 17.9;Undifferentiated spermatogonia: 5.2" "Cell type enhanced" "Detected in some" "Ductal cells: 21.0;Neuronal cells: 17.9;Spermatogenic cell types: 5.2" "Group enriched" "Detected in some" 7 "cerebellar inhibitory: 26.3;upper rhombic lip: 42.8" "Cancer enhanced" "Detected in single" "Kidney Chromophobe (TCGA): 1.0" "Region enriched" "Detected in many" 21 "cerebellum: 96.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 4.5" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1833 "Collecting ducts: 183304.0" "Group enriched" "Detected in some" 22852 "fallopian tube: 1914995.8;lymphoid tissue: 3608506.4;ovary: 2027407.6;salivary gland: 1589961.5" HPA069297 Approved "Nucleoli,Cytokinetic bridge,Cytosol" Yes NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 65: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 58 Nucleoli "Cytokinetic bridge, Cytosol" "HPA069297: " "potential prognostic favorable (8.23e-4)" PRR36 ENSG00000183248 "Proline rich 36" Q9H6K5 19 7868719-7874390 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 46.0;pituitary gland: 27.8" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Brain excitatory neurons: 13.5;Brain inhibitory neurons: 11.7;Breast hormone-responsive cells: 11.1;Corticotrophs: 11.7;Gonadotrophs: 22.2;Lactotrophs: 11.9;Oocytes: 18.4;Other brain neurons: 14.6" "Cell type enhanced" "Detected in many" "Oocytes: 18.4;Pituitary endocrine cells: 22.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 17.0" "Breast - Breast glandular cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 6568523.1;Microglia and Neuropil: 5952202.2;Neurons: 3553636.8" "Tissue enriched" "Detected in some" "cerebral cortex: 22886806.0" HPA062741 Uncertain Approved "Nucleoplasm,Nuclear speckles,Golgi apparatus" Yes No "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 4 "Golgi apparatus" "Nucleoplasm, Nuclear speckles" "HPA062741: " "unprognostic (5.27e-3)" "unprognostic (2.66e-2)" "unprognostic (8.81e-2)" "unprognostic (1.46e-1)" "unprognostic (2.86e-1)" "unprognostic (2.11e-1)" "unprognostic (3.58e-1)" "unprognostic (2.15e-1)" "unprognostic (1.85e-2)" "unprognostic (4.39e-2)" "unprognostic (2.62e-1)" "unprognostic (1.15e-3)" "unprognostic (4.57e-2)" "unprognostic (4.67e-3)" "unprognostic (2.43e-1)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.94e-2)" "unprognostic (2.40e-3)" "unprognostic (2.45e-1)" "unprognostic (3.39e-1)" PRR5L "FLJ14213, PROTOR-2" ENSG00000135362 "Proline rich 5 like" Q6MZQ0 11 36296288-36465204 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.4;intestine: 32.5;lymphoid tissue: 34.3" "Cell type enhanced" "Detected in many" "Colonocytes: 88.3;Late spermatids: 76.9;Lymphatic endothelial cells: 80.2;NK-cells: 103.8;Oligodendrocytes: 340.5;Salivary duct cells: 109.3;Salivary ionocytes: 115.8" "Cell type enhanced" "Detected in many" "Glial cells: 340.5" "Cell type enhanced" "Detected in many" "leukocyte: 160.0;oligodendrocyte: 546.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 46.9" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2244 "Collecting ducts: 163859.4;Large ducts: 367376.3;Oocytes: 141976.2" "Not detected" "Not detected" HPA070174 Approved "Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 30: White matter - Myelination" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 17 "Cytokinetic bridge, Cytosol" "HPA070174: " "unprognostic (3.95e-1)" "unprognostic (1.45e-1)" "unprognostic (2.15e-1)" "unprognostic (5.83e-2)" "unprognostic (2.13e-1)" "unprognostic (1.52e-2)" "unprognostic (1.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.16e-1)" "unprognostic (1.16e-2)" "unprognostic (5.05e-3)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (1.19e-1)" "unprognostic (5.21e-2)" "unprognostic (1.73e-1)" "unprognostic (1.95e-2)" "unprognostic (8.69e-2)" "unprognostic (8.65e-2)" "unprognostic (3.87e-2)" "unprognostic (3.90e-1)" "unprognostic (1.56e-2)" "unprognostic (1.21e-1)" "unprognostic (1.60e-1)" "potential prognostic favorable (2.33e-4)" "unprognostic (2.74e-2)" "unprognostic (7.84e-2)" "unprognostic (1.07e-2)" "unprognostic (1.84e-1)" "unprognostic (4.94e-2)" "unprognostic (2.26e-1)" PRR9 ENSG00000203783 "Proline rich 9" Q5T870 1 153217584-153219310 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 54.2" "Group enriched" "Detected in some" 4 "Late spermatids: 18.1;Syncytiotrophoblasts: 23.9" "Group enriched" "Detected in some" 9 "Spermatogenic cell types: 18.1;Trophoblast cells: 23.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 12.4;Head and Neck Squamous Cell Carcinoma (TCGA): 17.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "colorectal cancer: 10.4;testis cancer: 16.4" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA027714 Approved Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 9: Skin - Hair follicle development" "Cluster 47: Endothelial cells - Vasculature" "Cluster 32: Non-specific - Cell proliferation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" Cytosol "Nucleoplasm, Vesicles" "HPA027714: " "unprognostic (1.69e-2)" "unprognostic (2.72e-1)" "unprognostic (4.10e-1)" "unprognostic (3.48e-1)" "unprognostic (2.89e-1)" "unprognostic (1.65e-1)" "unprognostic (5.20e-3)" "unprognostic (4.03e-1)" "unprognostic (7.31e-2)" "unprognostic (3.27e-1)" PRRG2 PRGP2 ENSG00000126460 "Proline rich and Gla domain 2" O14669 19 49580646-49591004 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 26.6" "Cell type enhanced" "Detected in many" "Colonocytes: 42.2;Enterocytes: 45.7;Esophageal apical cells: 84.8;Esophageal suprabasal cells: 40.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 84.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA010702 Approved Approved Nucleoplasm,Nucleoli,Cytosol No NA "Cluster 33: Thyroid gland - Tissue development" "Cluster 25: Non-specific - Transcription" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 "Nucleoplasm, Nucleoli" Cytosol "HPA010702: " "unprognostic (1.77e-2)" "unprognostic (1.93e-1)" "unprognostic (1.45e-1)" "unprognostic (3.19e-1)" "unprognostic (1.03e-2)" "unprognostic (1.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.17e-1)" "unprognostic (3.04e-1)" "unprognostic (2.56e-1)" "potential prognostic favorable (3.75e-4)" "unprognostic (8.13e-3)" "potential prognostic favorable (3.28e-4)" "unprognostic (4.01e-1)" "unprognostic (8.65e-2)" "unprognostic (9.46e-2)" "unprognostic (4.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.83e-1)" "unprognostic (3.87e-2)" "unprognostic (8.95e-2)" "unprognostic (2.85e-1)" "unprognostic (2.14e-1)" "unprognostic (4.38e-1)" "potential prognostic unfavorable (6.03e-4)" "unprognostic (3.79e-1)" "unprognostic (2.04e-1)" "unprognostic (1.06e-1)" "unprognostic (8.76e-2)" "unprognostic (9.75e-2)" PRRX2 "PMX2, PRX2" ENSG00000167157 "Paired related homeobox 2" Q99811 9 129665647-129722674 "Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 52.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 29.2;Breast myoepithelial cells: 21.5;Early spermatids: 91.2;Endometrial secretory cells: 72.6;Fibro-adipogenic progenitors: 33.2;Fibroblasts: 76.9;Late primary spermatocytes: 45.3;Pericytes: 37.6;Suprabasal keratinocytes: 21.2;Undifferentiated spermatogonia: 37.5;Vascular smooth muscle cells: 38.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 76.9;Secretory cells: 72.6;Spermatogenic cell types: 91.2" "Group enriched" "Detected in some" 9 "fibroblast: 7.2;oligodendrocyte precursor cell: 7.9;vascular associated smooth muscle cell: 3.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 19.0" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006607, HPA026808" Approved Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Nuclear bodies" "HPA006607: , HPA026808: " "unprognostic (1.12e-1)" "unprognostic (2.94e-3)" "unprognostic (2.60e-1)" "unprognostic (2.32e-1)" "unprognostic (7.55e-3)" "unprognostic (1.43e-1)" "unprognostic (6.43e-2)" "unprognostic (2.06e-1)" "unprognostic (2.49e-3)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (1.81e-2)" "unprognostic (1.73e-1)" "unprognostic (2.91e-2)" "unprognostic (2.43e-2)" "unprognostic (1.37e-1)" "unprognostic (5.23e-2)" "unprognostic (2.26e-2)" "unprognostic (1.29e-1)" "unprognostic (5.09e-2)" "unprognostic (4.75e-3)" "potential prognostic unfavorable (9.20e-4)" "unprognostic (8.30e-2)" "unprognostic (2.46e-1)" "unprognostic (1.29e-2)" "unprognostic (8.55e-3)" PRSS27 "CAPH2, MPN" ENSG00000172382 "Serine protease 27" Q9BQR3 16 2712419-2720551 "Enzymes, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "cervix: 101.3;esophagus: 374.0;vagina: 125.1" "Cell type enriched" "Detected in many" 73 "Esophageal apical cells: 7187.0" "Cell type enriched" "Detected in many" 73 "Apical squamous epithelial cells: 7187.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 27.3;Head and Neck Squamous Cell Carcinoma (TCGA): 37.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 4.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Tissue enhanced" "Detected in many" "skin: 24397.3" "CAB024920, HPA028848" Approved Approved Vesicles "Secreted to digestive system" Enzyme NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 1 Vesicles "CAB024920: , HPA028848: " "unprognostic (8.67e-2)" "unprognostic (6.28e-3)" "unprognostic (1.88e-1)" "unprognostic (1.47e-1)" "unprognostic (8.07e-2)" "unprognostic (2.76e-2)" "unprognostic (3.29e-1)" "unprognostic (2.61e-1)" "unprognostic (1.09e-1)" "unprognostic (2.17e-1)" "unprognostic (3.65e-1)" "unprognostic (2.97e-1)" "unprognostic (4.24e-2)" "unprognostic (2.75e-2)" "unprognostic (8.08e-3)" "unprognostic (3.27e-2)" "unprognostic (1.81e-1)" "unprognostic (2.12e-1)" "unprognostic (2.39e-3)" "unprognostic (1.29e-1)" PRSS55 "CT153, T-SP1, UNQ9391" ENSG00000184647 "Serine protease 55" Q6UWB4 8 10525532-10554166 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 54 "testis: 26.0" "Group enriched" "Detected in some" 10 "Early spermatids: 174.1;Late primary spermatocytes: 101.5;Late spermatids: 49.9" "Cell type enriched" "Detected in some" 17 "Spermatogenic cell types: 174.1" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 12.0" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA027977 Approved Acrosome "Intracellular and membrane" Enzyme NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Acrosome "HPA027977: " PRXL2B "C1orf93, FAM213B, MGC26818" ENSG00000157870 "Peroxiredoxin like 2B" Q8TBF2 1 2586491-2591469 "Enzymes, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 6.8;Brain inhibitory neurons: 7.3;Enterocytes: 12.0;Ependymal cells: 9.4;Gastric progenitor cells: 12.8;Megakaryocytes: 6.2;Other brain neurons: 13.0;Papillary tip epithelial cells: 9.3;Renal collecting duct principal cells: 10.8" "Cell type enhanced" "Detected in many" "Ductal cells: 10.8;Enterocytes: 12.0;Neuronal cells: 13.0;Proliferating cells: 12.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 7192205.2;Fallopian tube cells: 8520757.7" "Tissue enhanced" "Detected in many" "cerebral cortex: 5547798.9" HPA006403 Approved Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 64: Renal epithelial cells - Ion transport & homeostasis" 2 Cytosol Nucleoplasm "HPA006403: " "unprognostic (4.29e-3)" "unprognostic (3.05e-2)" "unprognostic (9.76e-3)" "unprognostic (5.39e-2)" "unprognostic (6.27e-2)" "unprognostic (2.62e-1)" "unprognostic (1.64e-1)" "unprognostic (5.96e-2)" "unprognostic (1.99e-2)" "potential prognostic favorable (7.06e-8)" "unprognostic (1.04e-1)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (7.59e-4)" "unprognostic (8.89e-2)" "unprognostic (1.83e-1)" "unprognostic (9.36e-3)" "unprognostic (2.82e-1)" "unprognostic (9.44e-3)" "unprognostic (2.59e-1)" "potential prognostic unfavorable (9.43e-4)" "unprognostic (1.38e-1)" "unprognostic (2.82e-1)" "unprognostic (2.27e-1)" "unprognostic (1.37e-1)" "unprognostic (3.24e-1)" "unprognostic (3.50e-2)" "unprognostic (3.83e-1)" "unprognostic (2.78e-2)" "unprognostic (2.11e-1)" PSD3 "DKFZp761K1423, EFA6D, EFA6R, HCA67, KIAA0942" ENSG00000156011 "Pleckstrin and Sec7 domain containing 3" Q9NYI0 8 18527303-19084730 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1567.7;Bergmann glia: 1487.7;Cardiomyocytes: 1236.3;Early spermatids: 1018.4;Foveolar cells: 965.5;Somatotrophs: 1346.3" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 1567.7;Glial cells: 1487.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts, Spleen - Endothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 56524670.1;Microglia and Neuropil: 74481652.2;Neurons: 113828672.0" "Group enriched" "Detected in some" "cerebral cortex: 76263747.0;intestine: 21414276.0" HPA002455 Enhanced Approved "Nucleoplasm,Vesicles,Cytosol,Calyx,Mid piece,Principal piece,End piece" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 18: Adrenal cortex cells - Steroidogensis" 7 "Nucleoplasm, Vesicles" "Cytosol, Calyx, Mid piece, Principal piece, End piece" "HPA002455: " "unprognostic (8.40e-3)" "unprognostic (9.64e-2)" "unprognostic (5.49e-2)" "unprognostic (4.45e-1)" "unprognostic (2.72e-2)" "unprognostic (2.01e-2)" "unprognostic (3.46e-1)" "potential prognostic favorable (7.69e-4)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (1.28e-5)" "unprognostic (1.02e-2)" "unprognostic (7.55e-2)" "unprognostic (7.10e-2)" "unprognostic (6.56e-3)" "unprognostic (3.31e-2)" "unprognostic (1.20e-1)" "unprognostic (1.07e-3)" "unprognostic (1.28e-1)" "unprognostic (1.84e-2)" "unprognostic (2.98e-1)" "unprognostic (1.25e-2)" "unprognostic (5.49e-2)" "unprognostic (1.13e-2)" "unprognostic (3.97e-2)" "unprognostic (1.92e-1)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.62e-2)" "unprognostic (2.36e-1)" "unprognostic (8.19e-2)" "unprognostic (2.24e-2)" PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 479.8;Neutrophil progenitors: 647.4;Neutrophils: 2031.4;Oligodendrocytes: 545.2" "Cell type enhanced" "Detected in all" "Neutrophils: 2031.4" "Cell type enhanced" "Detected in all" "oligodendrocyte: 755.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 726186.5;Macrophages: 619970.5;Microglia and Neuropil: 948061.8" "Tissue enriched" "Detected in some" "lymphoid tissue: 210277.6" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 63 "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: , HPA067496: " "unprognostic (7.43e-3)" "unprognostic (2.99e-1)" "unprognostic (9.78e-3)" "unprognostic (7.61e-3)" "unprognostic (5.67e-2)" "unprognostic (6.43e-3)" "unprognostic (3.48e-1)" "unprognostic (8.87e-2)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (3.47e-4)" "potential prognostic favorable (3.35e-7)" "unprognostic (1.24e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (2.07e-5)" "unprognostic (9.28e-2)" "unprognostic (1.47e-2)" "unprognostic (2.52e-1)" "unprognostic (4.03e-1)" "unprognostic (1.88e-1)" "unprognostic (9.10e-3)" "unprognostic (1.67e-3)" "unprognostic (2.40e-3)" "unprognostic (1.88e-2)" "unprognostic (2.34e-1)" "unprognostic (3.28e-2)" "unprognostic (9.36e-3)" "unprognostic (2.17e-1)" "unprognostic (8.30e-2)" "unprognostic (3.10e-1)" "unprognostic (4.37e-1)" "unprognostic (3.73e-1)" PSG11 "MGC22484, PSG13, PSG14" ENSG00000243130 "Pregnancy specific beta-1-glycoprotein 11" Q9UQ72 19 43007656-43026474 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 88 "placenta: 49.9" "Cell type enriched" "Detected in some" 14 "Syncytiotrophoblasts: 213.2" "Cell type enriched" "Detected in some" 14 "Trophoblast cells: 213.2" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "breast cancer: 2.5;Rhabdoid: 2.7;testis cancer: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042240, HPA046327" Enhanced Approved Vesicles "Secreted in female reproductive system" "No annotated function" NA NA 21000000 "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." Vesicles "HPA042240: , HPA046327: " PSIP1 "DFS70, LEDGF, p52, p75, PSIP2" ENSG00000164985 "PC4 and SFRS1 interacting protein 1" O75475 9 15464066-15510995 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 340.4;Undifferentiated spermatogonia: 325.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 94546471.6" "Tissue enhanced" "Detected in all" "ovary: 83488253.7" "CAB013718, HPA019697" Enhanced Enhanced Nucleoplasm NA NA 46000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 7: Non-specific - Transcription" 37 Nucleoplasm "CAB013718: , HPA019697: " "unprognostic (6.17e-3)" "unprognostic (2.32e-1)" "unprognostic (4.64e-2)" "unprognostic (1.31e-1)" "unprognostic (3.41e-1)" "unprognostic (2.40e-2)" "unprognostic (1.61e-1)" "unprognostic (1.33e-1)" "unprognostic (1.66e-1)" "unprognostic (1.85e-2)" "potential prognostic favorable (1.42e-4)" "unprognostic (2.23e-3)" "unprognostic (6.96e-2)" "unprognostic (1.98e-3)" "unprognostic (4.36e-2)" "unprognostic (1.05e-1)" "unprognostic (1.11e-2)" "unprognostic (9.79e-2)" "unprognostic (1.50e-2)" "unprognostic (7.71e-2)" "unprognostic (3.29e-2)" "unprognostic (3.83e-2)" "unprognostic (5.66e-2)" "unprognostic (2.53e-2)" "unprognostic (3.20e-2)" "unprognostic (2.02e-1)" "unprognostic (1.58e-2)" "unprognostic (1.37e-1)" "unprognostic (2.12e-1)" "unprognostic (4.10e-1)" "unprognostic (3.54e-1)" PSKH1 ENSG00000159792 "Protein serine kinase H1" P11801 16 67893254-67929676 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 50.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Skin - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053927, HPA062763" Approved Supported "Nuclear speckles,Plasma membrane,Primary cilium,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 70: Non-specific - Protein processing" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 "Nuclear speckles" "Plasma membrane, Primary cilium, Cytosol" "HPA053927: , HPA062763: " "unprognostic (2.14e-1)" "unprognostic (1.42e-2)" "unprognostic (2.42e-1)" "unprognostic (6.76e-2)" "unprognostic (1.08e-1)" "unprognostic (2.03e-1)" "unprognostic (1.38e-1)" "unprognostic (1.17e-3)" "unprognostic (1.57e-1)" "unprognostic (2.80e-2)" "potential prognostic favorable (7.28e-7)" "unprognostic (3.28e-1)" "potential prognostic favorable (8.05e-6)" "unprognostic (3.08e-2)" "unprognostic (2.18e-2)" "unprognostic (3.27e-2)" "unprognostic (1.29e-1)" "unprognostic (1.99e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (4.26e-2)" "unprognostic (3.59e-2)" "unprognostic (1.26e-3)" "unprognostic (4.44e-2)" "unprognostic (2.68e-1)" "unprognostic (3.25e-2)" "unprognostic (4.22e-1)" "unprognostic (2.45e-1)" "unprognostic (1.12e-1)" "unprognostic (3.58e-3)" "unprognostic (1.84e-1)" PSKH2 ENSG00000147613 "Protein serine kinase H2" Q96QS6 8 86047109-86088621 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "retina: 2.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 53.8;Megakaryocyte progenitors: 11.0;Podocytes: 3.4;Renal collecting duct intercalated cells: 7.1;Rod photoreceptor cells: 32.0" "Cell type enriched" "Detected in some" 4 "Neuronal cells: 53.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 1.1;Testicular Germ Cell Tumor (TCGA): 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015095, HPA056839" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 42: Retina - Visual perception" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Photoreceptor cells - Phototransduction" 14 Nucleoplasm "Nuclear bodies, Cytosol" "HPA015095: , HPA056839: " "unprognostic (1.92e-1)" PSMA4 "HC9, HsT17706" ENSG00000041357 "Proteasome 20S subunit alpha 4" P25789 15 78540405-78552417 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 555.5;Early spermatids: 693.2;Extravillous trophoblasts: 536.3;Late primary spermatocytes: 722.1;Migrating cytotrophoblasts: 538.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 722.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004973, HPA055466, HPA060613" Supported Supported "Nucleoplasm,Vesicles,Cytosol,Connecting piece,Flagellar centriole,Mid piece" No No 8300000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 170 "Nucleoplasm, Cytosol" "Vesicles, Connecting piece, Flagellar centriole, Mid piece" "CAB004973: , HPA055466: , HPA060613: " "unprognostic (1.02e-1)" "unprognostic (7.49e-2)" "unprognostic (2.22e-1)" "unprognostic (5.95e-2)" "unprognostic (1.72e-1)" "unprognostic (8.71e-2)" "unprognostic (1.78e-1)" "unprognostic (1.32e-2)" "potential prognostic unfavorable (7.52e-4)" "unprognostic (1.21e-2)" "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (9.88e-4)" "unprognostic (1.99e-2)" "potential prognostic unfavorable (5.30e-5)" "potential prognostic unfavorable (8.55e-5)" "unprognostic (1.21e-2)" "potential prognostic favorable (8.10e-4)" "unprognostic (9.62e-2)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "potential prognostic unfavorable (4.80e-4)" "unprognostic (1.64e-1)" "unprognostic (5.72e-2)" "unprognostic (8.96e-2)" "unprognostic (7.04e-2)" "unprognostic (3.32e-3)" "unprognostic (1.36e-1)" "unprognostic (1.25e-1)" "unprognostic (9.35e-2)" "unprognostic (7.05e-3)" PSMA6 "IOTA, MGC22756, MGC2333, MGC23846, p27K, PROS27" ENSG00000100902 "Proteasome 20S subunit alpha 6" P60900 14 35278633-35317493 "Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Astrocytes: 34.5;Bergmann glia: 36.1;Brain excitatory neurons: 48.7;Brain inhibitory neurons: 48.4;Choroid plexus epithelial cells: 46.4;Ependymal cells: 25.7;Microglia: 45.3;Oligodendrocyte progenitor cells: 41.6;Oligodendrocytes: 47.4;Other brain neurons: 57.1" "Group enriched" "Detected in many" 8 "Ciliated cells: 46.4;Glial cells: 47.4;Neuronal cells: 57.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA003049 Approved Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol,Perinuclear theca,Calyx,Connecting piece,Flagellar centriole,Mid piece,End piece" NA NA 15000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 22: Non-specific - Basic cellular functions" 156 Nucleoplasm "Primary cilium, Primary cilium tip, Cytosol, Perinuclear theca, Calyx, Connecting piece, Flagellar centriole, Mid piece, End piece" "HPA003049: " "unprognostic (1.96e-1)" "unprognostic (3.24e-2)" "unprognostic (1.92e-1)" "unprognostic (5.46e-2)" "unprognostic (6.60e-3)" "unprognostic (1.85e-1)" "unprognostic (1.71e-1)" "potential prognostic favorable (4.58e-4)" "unprognostic (1.61e-2)" "unprognostic (1.11e-2)" "potential prognostic favorable (7.65e-4)" "unprognostic (9.38e-2)" "unprognostic (1.19e-1)" "unprognostic (9.32e-3)" "potential prognostic unfavorable (5.36e-4)" "unprognostic (1.04e-2)" "unprognostic (1.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.65e-1)" "unprognostic (1.66e-2)" "unprognostic (8.95e-2)" "potential prognostic unfavorable (3.47e-4)" "unprognostic (6.34e-2)" "unprognostic (4.07e-2)" "unprognostic (1.65e-1)" "unprognostic (1.94e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (3.93e-1)" "unprognostic (4.63e-2)" "unprognostic (4.38e-2)" PSMA7 "C6, HSPC, RC6-1, XAPC7" ENSG00000101182 "Proteasome 20S subunit alpha 7" O14818 20 62136733-62143440 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 740.0" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 1107.4;Esophageal suprabasal cells: 1124.1;Gastric progenitor cells: 1353.4;Syncytiotrophoblasts: 1048.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB046007, CAB046008, HPA047266, HPA071263" Approved Uncertain "Vesicles,Principal piece" NA NA 15000000 "Cluster 29: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 160 "Vesicles, Principal piece" "CAB046007: , CAB046008: , HPA047266: , HPA071263: " "unprognostic (1.42e-1)" "unprognostic (2.38e-3)" "unprognostic (5.26e-3)" "unprognostic (1.44e-1)" "unprognostic (1.62e-1)" "unprognostic (1.28e-1)" "unprognostic (9.51e-2)" "unprognostic (4.97e-2)" "unprognostic (2.91e-3)" "unprognostic (1.52e-3)" "potential prognostic favorable (3.53e-4)" "potential prognostic unfavorable (7.71e-4)" "unprognostic (1.57e-1)" "validated prognostic unfavorable (9.41e-6)" "validated prognostic unfavorable (5.26e-4)" "unprognostic (1.05e-1)" "unprognostic (1.73e-2)" "unprognostic (1.34e-1)" "unprognostic (1.70e-1)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (2.84e-2)" "unprognostic (1.06e-2)" "unprognostic (1.06e-1)" "unprognostic (1.82e-2)" "unprognostic (4.01e-3)" "unprognostic (4.12e-2)" "unprognostic (1.90e-1)" "unprognostic (1.94e-1)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" PSMA8 "MGC26605, PSMA7L" ENSG00000154611 "Proteasome 20S subunit alpha 8" Q8TAA3 18 26133852-26193355 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 15.8" "Group enriched" "Detected in some" 6 "Early primary spermatocytes: 288.2;Late primary spermatocytes: 126.2" "Cell type enriched" "Detected in some" 9 "Spermatogenic cell types: 288.2" "Low cell type specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Gallbladder cancer: 3.6;lymphoma: 6.9;Myeloma: 3.9" "Testis - Early spermatids, Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA071263 Uncertain "Vesicles,Principal piece" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 57: Testis - Spermatogenesis" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 21 "Vesicles, Principal piece" "HPA071263: " PSMB5 MB1 ENSG00000100804 "Proteasome 20S subunit beta 5" P28074 14 23016543-23035230 "Enzymes, Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 476.5;Esophageal apical cells: 416.5;Esophageal basal cells: 490.4;Esophageal suprabasal cells: 539.0;Extravillous trophoblasts: 521.2;Migrating cytotrophoblasts: 470.7;Syncytiotrophoblasts: 483.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA049518, HPA061796" Approved Supported "Nucleoplasm,Centrosome,Mid piece,Principal piece" NA NA 4400000 "Cluster 13: Non-specific - Mitochondria" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 119 Nucleoplasm "Centrosome, Mid piece, Principal piece" "HPA049518: , HPA061796: " "potential prognostic unfavorable (4.44e-4)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-2)" "potential prognostic favorable (9.63e-5)" "unprognostic (3.01e-1)" "unprognostic (1.48e-1)" "unprognostic (1.36e-2)" "potential prognostic unfavorable (2.60e-5)" "unprognostic (2.64e-2)" "unprognostic (3.99e-3)" "unprognostic (2.02e-1)" "unprognostic (3.99e-2)" "validated prognostic unfavorable (7.07e-6)" "validated prognostic unfavorable (2.93e-6)" "unprognostic (2.72e-3)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (3.42e-2)" "unprognostic (2.16e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.91e-1)" "unprognostic (2.07e-1)" "unprognostic (2.57e-1)" "unprognostic (2.22e-1)" "unprognostic (2.46e-1)" "unprognostic (3.98e-2)" "unprognostic (6.57e-2)" "unprognostic (1.10e-1)" "unprognostic (4.09e-2)" "unprognostic (4.30e-1)" "unprognostic (6.98e-3)" PSMB6 "DELTA, Y" ENSG00000142507 "Proteasome 20S subunit beta 6" P28072 17 4796144-4798502 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 694.1;Esophageal apical cells: 728.5;Esophageal basal cells: 582.2;Esophageal suprabasal cells: 750.6;Migrating cytotrophoblasts: 568.0;Syncytiotrophoblasts: 740.4" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 728.5;Suprabasal cells: 750.6;Trophoblast cells: 740.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA023312, HPA063656" Supported Supported Nucleoplasm,Mitochondria,Cytosol NA NA 3200000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 105 "Nucleoplasm, Cytosol" Mitochondria "HPA023312: , HPA063656: " "unprognostic (4.43e-3)" "unprognostic (5.40e-2)" "potential prognostic unfavorable (2.58e-4)" "unprognostic (3.00e-3)" "unprognostic (7.40e-2)" "unprognostic (8.18e-2)" "unprognostic (3.20e-2)" "unprognostic (9.82e-2)" "unprognostic (2.46e-2)" "unprognostic (3.33e-3)" "unprognostic (1.08e-1)" "unprognostic (5.37e-2)" "unprognostic (1.26e-3)" "unprognostic (3.13e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (9.82e-5)" "unprognostic (1.57e-1)" "unprognostic (1.22e-1)" "unprognostic (7.62e-2)" "unprognostic (8.51e-3)" "unprognostic (3.45e-1)" "unprognostic (4.57e-2)" "unprognostic (2.39e-1)" "unprognostic (1.77e-1)" "unprognostic (6.07e-2)" "unprognostic (4.31e-1)" "unprognostic (1.93e-1)" "unprognostic (3.11e-2)" "unprognostic (2.06e-1)" "unprognostic (1.47e-2)" "unprognostic (3.10e-2)" PSMB7 Z ENSG00000136930 "Proteasome 20S subunit beta 7" Q99436 9 124353465-124415444 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Hydrolase, Protease, Threonine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 551.5;Late primary spermatocytes: 720.1;Late spermatids: 685.2;Oocytes: 584.8;Syncytiotrophoblasts: 597.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA052408, HPA054902" Supported Supported "Nucleoplasm,Nuclear bodies,Primary cilium,Cytosol" No No 5000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 153 Nucleoplasm "Nuclear bodies, Primary cilium, Cytosol" "HPA052408: , HPA054902: " "unprognostic (2.45e-3)" "unprognostic (3.28e-2)" "unprognostic (2.11e-1)" "unprognostic (2.74e-2)" "unprognostic (5.81e-2)" "unprognostic (2.80e-3)" "unprognostic (2.51e-1)" "unprognostic (7.01e-3)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "potential prognostic favorable (1.62e-6)" "unprognostic (1.67e-2)" "unprognostic (4.78e-2)" "unprognostic (2.20e-2)" "unprognostic (2.84e-2)" "potential prognostic unfavorable (2.86e-5)" "unprognostic (2.69e-2)" "unprognostic (1.06e-1)" "unprognostic (8.69e-2)" "unprognostic (1.06e-1)" "unprognostic (3.83e-2)" "unprognostic (9.25e-2)" "unprognostic (1.61e-1)" "unprognostic (3.72e-1)" "unprognostic (3.46e-1)" "unprognostic (1.59e-1)" "unprognostic (6.14e-2)" "unprognostic (2.92e-1)" "unprognostic (6.86e-2)" "unprognostic (5.51e-2)" "unprognostic (3.65e-2)" PSMB8 "beta5i, D6S216E, LMP7, PSMB5i, RING10" ENSG00000204264 "Proteasome 20S subunit beta 8" P28062 6 32840717-32844679 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Immunity" "Hydrolase, Protease, Threonine protease" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast lactating cells: 74.8;Enterocytes: 85.7;Megakaryocytes: 80.4;Platelets: 73.3" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "endothelial cell: 47.4;leukocyte: 52.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA046995, HPA050327" Enhanced Approved "Vesicles,Cytokinetic bridge" Yes No 1900000 "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 22: Non-specific - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 40 Vesicles "Cytokinetic bridge" "HPA046995: , HPA050327: " "unprognostic (3.53e-1)" "unprognostic (2.98e-2)" "unprognostic (3.40e-1)" "unprognostic (2.90e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-1)" "unprognostic (2.94e-2)" "unprognostic (2.43e-1)" "unprognostic (1.09e-1)" "unprognostic (7.61e-3)" "unprognostic (2.13e-1)" "unprognostic (1.39e-1)" "unprognostic (1.82e-1)" "unprognostic (1.81e-1)" "unprognostic (9.03e-3)" "unprognostic (1.07e-2)" "unprognostic (4.11e-2)" "unprognostic (1.35e-1)" "unprognostic (2.15e-2)" "unprognostic (3.81e-2)" "unprognostic (3.36e-3)" "unprognostic (1.47e-3)" "unprognostic (1.02e-1)" "unprognostic (1.08e-1)" "unprognostic (4.76e-3)" "unprognostic (3.53e-2)" "unprognostic (5.29e-2)" "unprognostic (2.11e-1)" "unprognostic (1.71e-1)" "unprognostic (6.62e-3)" "unprognostic (3.57e-2)" PSMC3 "RPT5, TBP-1, TBP1" ENSG00000165916 "Proteasome 26S subunit, ATPase 3" P17980 11 47418769-47426473 "Disease related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cataract, Deafness, Intellectual disability, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 315.0;Extravillous trophoblasts: 311.2;Late primary spermatocytes: 330.1;Late spermatids: 321.7;Syncytiotrophoblasts: 439.9" "Cell type enhanced" "Detected in all" "Trophoblast cells: 439.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA006065 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 280000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 202 "Nucleoplasm, Cytosol" "Nuclear bodies" "HPA006065: " "unprognostic (1.12e-3)" "unprognostic (2.58e-2)" "unprognostic (3.76e-2)" "unprognostic (1.15e-1)" "unprognostic (6.41e-2)" "unprognostic (4.22e-1)" "unprognostic (8.75e-2)" "unprognostic (9.60e-2)" "unprognostic (4.77e-2)" "unprognostic (2.82e-3)" "unprognostic (1.53e-1)" "unprognostic (8.06e-2)" "unprognostic (2.54e-3)" "unprognostic (2.82e-3)" "unprognostic (1.20e-2)" "unprognostic (1.01e-3)" "potential prognostic unfavorable (1.19e-5)" "unprognostic (2.81e-2)" "unprognostic (4.83e-2)" "unprognostic (7.16e-2)" "unprognostic (1.14e-1)" "unprognostic (8.27e-3)" "unprognostic (1.39e-1)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" "unprognostic (2.91e-1)" "unprognostic (1.21e-1)" "unprognostic (3.65e-1)" "unprognostic (1.23e-1)" "unprognostic (5.38e-2)" "unprognostic (1.28e-1)" PSMC4 "MGC13687, MGC23214, MGC8570, MIP224, RPT3, S6, TBP-7, TBP7" ENSG00000013275 "Proteasome 26S subunit, ATPase 4" P43686 19 39971165-39981764 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 156.3;Hofbauer cells: 145.7;Late primary spermatocytes: 236.5;Late spermatids: 139.8;Syncytiotrophoblasts: 322.1" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 236.5;Trophoblast cells: 322.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA002044, HPA005471" Approved Supported "Nucleoplasm,Vesicles,Basal body,Cytosol,Mid piece,Principal piece" NA NA 190000 "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 191 "Nucleoplasm, Cytosol" "Vesicles, Basal body, Mid piece, Principal piece" "HPA002044: , HPA005471: " "unprognostic (8.02e-2)" "unprognostic (4.04e-1)" "unprognostic (2.30e-1)" "unprognostic (3.31e-2)" "unprognostic (3.53e-3)" "unprognostic (3.58e-2)" "unprognostic (5.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.68e-3)" "potential prognostic unfavorable (5.25e-4)" "unprognostic (1.60e-2)" "unprognostic (2.19e-3)" "unprognostic (3.64e-1)" "potential prognostic unfavorable (3.16e-5)" "unprognostic (3.61e-3)" "potential prognostic unfavorable (1.04e-5)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "unprognostic (1.83e-1)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (4.11e-2)" "unprognostic (3.14e-1)" "unprognostic (4.33e-1)" "unprognostic (1.85e-1)" "unprognostic (3.65e-1)" "unprognostic (9.69e-3)" "unprognostic (1.40e-1)" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (6.89e-5)" PSMC6 "p42, RPT5" ENSG00000100519 "Proteasome 26S subunit, ATPase 6" P62333 14 52707178-52728590 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 607.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 607.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA042823 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 230000 "Cluster 25: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 84: Apical squamous epithelium - Cornification" 188 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042823: " "potential prognostic unfavorable (2.69e-4)" "unprognostic (1.69e-2)" "unprognostic (9.61e-2)" "unprognostic (1.88e-3)" "unprognostic (7.89e-2)" "unprognostic (6.43e-2)" "unprognostic (5.65e-2)" "unprognostic (8.30e-3)" "unprognostic (1.14e-2)" "unprognostic (3.56e-1)" "potential prognostic favorable (4.04e-7)" "unprognostic (1.78e-3)" "unprognostic (3.01e-1)" "potential prognostic unfavorable (3.60e-4)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (1.91e-5)" "unprognostic (9.25e-3)" "unprognostic (3.50e-2)" "unprognostic (3.20e-1)" "unprognostic (2.17e-1)" "unprognostic (2.05e-2)" "unprognostic (9.18e-3)" "unprognostic (1.21e-3)" "unprognostic (3.91e-2)" "unprognostic (1.64e-1)" "unprognostic (4.72e-3)" "unprognostic (1.78e-2)" "unprognostic (1.90e-1)" "unprognostic (5.98e-2)" "unprognostic (3.48e-1)" "unprognostic (1.60e-1)" PSMD10 p28 ENSG00000101843 "Proteasome 26S subunit, non-ATPase 10" O75832 X 108084207-108091549 "Predicted intracellular proteins" Apoptosis Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 156.6" "Cell type enhanced" "Detected in many" "Oocytes: 156.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 26456802.4" "Low tissue specificity" "Detected in all" "HPA002920, CAB010434" Approved Supported "Primary cilium tip,Cytosol,Perinuclear theca,Calyx,Mid piece,Principal piece" NA NA 190000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 122 "Cytosol, Mid piece" "Primary cilium tip, Perinuclear theca, Calyx, Principal piece" "CAB010434: , HPA002920: " "unprognostic (1.61e-1)" "validated prognostic unfavorable (2.38e-4)" "validated prognostic unfavorable (4.73e-4)" "unprognostic (4.94e-2)" "unprognostic (9.19e-2)" "unprognostic (1.23e-1)" "unprognostic (2.42e-1)" "unprognostic (1.28e-1)" "unprognostic (6.69e-3)" "unprognostic (1.02e-3)" "potential prognostic favorable (3.51e-8)" "unprognostic (1.37e-1)" "unprognostic (1.02e-2)" "unprognostic (3.16e-3)" "potential prognostic unfavorable (8.65e-5)" "unprognostic (2.75e-1)" "potential prognostic unfavorable (1.80e-4)" "unprognostic (8.43e-2)" "unprognostic (3.55e-1)" "unprognostic (3.38e-1)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (1.63e-1)" "unprognostic (3.24e-2)" "unprognostic (8.01e-2)" "unprognostic (3.25e-1)" "unprognostic (1.02e-1)" "unprognostic (5.65e-2)" "unprognostic (3.21e-1)" "unprognostic (3.30e-1)" "unprognostic (1.05e-1)" PSMD11 "MGC3844, p44.5, Rpn6, S9" ENSG00000108671 "Proteasome 26S subunit, non-ATPase 11" O00231 17 32444379-32483319 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 410.6" "Cell type enhanced" "Detected in all" "Trophoblast cells: 410.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA042275, HPA067433" Approved Approved "Nucleoplasm,Golgi apparatus,Perinuclear theca,Principal piece" NA NA 160000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 167 "Nucleoplasm, Golgi apparatus" "Perinuclear theca, Principal piece" "HPA042275: , HPA067433: " "unprognostic (9.23e-2)" "unprognostic (3.47e-3)" "unprognostic (2.01e-1)" "unprognostic (9.50e-2)" "unprognostic (4.84e-2)" "potential prognostic unfavorable (5.57e-4)" "unprognostic (1.69e-1)" "unprognostic (6.08e-2)" "unprognostic (5.42e-3)" "potential prognostic unfavorable (1.17e-4)" "unprognostic (2.92e-3)" "unprognostic (6.85e-2)" "unprognostic (1.37e-2)" "validated prognostic unfavorable (3.33e-5)" "validated prognostic unfavorable (1.22e-4)" "potential prognostic unfavorable (2.25e-5)" "unprognostic (3.76e-2)" "unprognostic (2.62e-2)" "unprognostic (4.32e-2)" "unprognostic (8.89e-2)" "unprognostic (1.32e-1)" "unprognostic (7.17e-3)" "unprognostic (4.32e-3)" "unprognostic (1.07e-1)" "unprognostic (5.99e-3)" "unprognostic (1.12e-2)" "unprognostic (1.16e-1)" "unprognostic (1.42e-1)" "unprognostic (2.56e-1)" "unprognostic (6.11e-2)" "unprognostic (2.42e-1)" PSMD2 "MGC14274, P97, Rpn1, S2, TRAP2" ENSG00000175166 "Proteasome 26S subunit ubiquitin receptor, non-ATPase 2" Q13200 3 184299198-184309050 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 300.1" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 271.9;Syncytiotrophoblasts: 289.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA045192, HPA062363" Enhanced Approved "Nucleoplasm,Cytokinetic bridge,Centriolar satellite,Cytosol,Flagellar centriole" Yes NA 640000 "Cluster 25: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 223 "Centriolar satellite, Cytosol, Flagellar centriole" "Nucleoplasm, Cytokinetic bridge" "HPA045192: , HPA062363: " "potential prognostic unfavorable (1.69e-5)" "unprognostic (2.98e-3)" "unprognostic (3.66e-1)" "unprognostic (2.15e-2)" "unprognostic (1.49e-1)" "unprognostic (2.30e-1)" "unprognostic (2.54e-1)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" "unprognostic (3.72e-3)" "unprognostic (1.24e-3)" "unprognostic (1.07e-3)" "unprognostic (3.21e-2)" "potential prognostic unfavorable (9.10e-6)" "unprognostic (2.06e-3)" "potential prognostic unfavorable (7.45e-5)" "unprognostic (8.53e-3)" "unprognostic (8.00e-3)" "unprognostic (6.97e-3)" "unprognostic (3.95e-1)" "unprognostic (1.41e-2)" "unprognostic (2.41e-3)" "unprognostic (7.64e-2)" "unprognostic (1.67e-1)" "unprognostic (1.41e-1)" "unprognostic (3.58e-1)" "unprognostic (2.66e-1)" "unprognostic (4.12e-1)" "unprognostic (1.69e-1)" "unprognostic (4.06e-2)" "unprognostic (2.64e-1)" PSMD3 "P58, Rpn3, S3, TSTA2" ENSG00000108344 "Proteasome 26S subunit, non-ATPase 3" O43242 17 39980807-39997959 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 242.1" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 195.8;Early spermatids: 286.2;Syncytiotrophoblasts: 331.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 286.2;Trophoblast cells: 331.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB017038, HPA048972" Approved Enhanced Nucleoplasm,Cytosol No No 12000000 "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 14: Neurons - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 209 Nucleoplasm Cytosol "CAB017038: , HPA048972: " "unprognostic (1.17e-1)" "unprognostic (7.33e-2)" "unprognostic (1.86e-1)" "unprognostic (3.33e-2)" "unprognostic (1.37e-1)" "unprognostic (1.02e-2)" "unprognostic (4.25e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-3)" "unprognostic (6.60e-3)" "unprognostic (3.58e-2)" "unprognostic (8.85e-2)" "unprognostic (3.90e-2)" "unprognostic (6.44e-3)" "potential prognostic unfavorable (4.19e-6)" "unprognostic (7.71e-3)" "unprognostic (2.18e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-3)" "unprognostic (1.55e-1)" "unprognostic (2.26e-1)" "unprognostic (2.81e-1)" "unprognostic (6.90e-2)" "unprognostic (3.78e-2)" "unprognostic (3.98e-2)" "unprognostic (1.46e-3)" "unprognostic (1.58e-2)" "unprognostic (3.96e-1)" "unprognostic (1.94e-1)" "unprognostic (1.21e-1)" "unprognostic (1.18e-1)" PSMD5 "KIAA0072, S5B" ENSG00000095261 "Proteasome 26S subunit, non-ATPase 5" Q16401 9 120815496-120842951 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA003216 Uncertain Approved "Nucleoplasm,Centrosome,Basal body,Cytosol,Connecting piece,Mid piece" No No 230000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 58: Skin - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Transcription" 78 "Nucleoplasm, Cytosol" "Centrosome, Basal body, Connecting piece, Mid piece" "HPA003216: " "unprognostic (1.21e-1)" "unprognostic (2.85e-2)" "unprognostic (6.96e-2)" "unprognostic (1.08e-1)" "unprognostic (2.46e-1)" "unprognostic (2.92e-3)" "unprognostic (1.43e-1)" "unprognostic (1.13e-1)" "unprognostic (4.74e-2)" "unprognostic (7.13e-2)" "potential prognostic favorable (2.84e-5)" "unprognostic (3.24e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-2)" "unprognostic (7.17e-2)" "unprognostic (5.27e-2)" "unprognostic (3.27e-2)" "unprognostic (5.64e-2)" "unprognostic (1.18e-1)" "unprognostic (3.95e-1)" "unprognostic (3.39e-1)" "unprognostic (2.41e-2)" "unprognostic (2.40e-2)" "unprognostic (2.00e-3)" "unprognostic (3.19e-2)" "unprognostic (1.47e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (1.72e-1)" "unprognostic (2.94e-1)" "unprognostic (2.11e-1)" PSMD7 "MOV34, P40, Rpn8, S12" ENSG00000103035 "Proteasome 26S subunit, non-ATPase 7" P51665 16 74296814-74306288 "Enzymes, Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 417.4;Esophageal apical cells: 481.9;Syncytiotrophoblasts: 819.3" "Cell type enhanced" "Detected in all" "Trophoblast cells: 819.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB019379, HPA049824, HPA056069" Enhanced Approved "Nucleoplasm,Acrosome,Equatorial segment,Mid piece,Principal piece" NA NA 72000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 124 "Nucleoplasm, Acrosome, Equatorial segment, Mid piece, Principal piece" "CAB019379: , HPA049824: , HPA056069: " "unprognostic (1.75e-3)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (9.46e-3)" "unprognostic (6.38e-3)" "unprognostic (2.43e-1)" "unprognostic (3.31e-1)" "unprognostic (3.29e-1)" "unprognostic (3.41e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (2.83e-2)" "unprognostic (4.32e-2)" "unprognostic (5.14e-2)" "unprognostic (5.48e-2)" "potential prognostic unfavorable (2.31e-4)" "unprognostic (3.78e-3)" "unprognostic (1.16e-3)" "unprognostic (4.45e-2)" "unprognostic (6.23e-2)" "unprognostic (8.14e-2)" "unprognostic (1.94e-1)" "unprognostic (5.39e-2)" "unprognostic (2.73e-2)" "unprognostic (5.30e-3)" "unprognostic (6.42e-3)" "unprognostic (1.03e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-1)" "unprognostic (1.51e-2)" "unprognostic (2.88e-1)" "unprognostic (2.41e-2)" "unprognostic (9.45e-2)" PSME3 "Ki, PA28-gamma, PA28G, REG-GAMMA" ENSG00000131467 "Proteasome activator subunit 3" P61289 17 42824385-42843760 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 301.4;Late spermatids: 177.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 301.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB008388, HPA012510" Supported Supported "Nucleoplasm,Primary cilium,Basal body,Cytosol" NA NA 21000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 184 Nucleoplasm "Primary cilium, Basal body, Cytosol" "CAB008388: , HPA012510: " "unprognostic (1.42e-1)" "unprognostic (8.38e-3)" "unprognostic (2.14e-1)" "unprognostic (2.41e-2)" "unprognostic (4.82e-3)" "unprognostic (8.20e-2)" "unprognostic (1.09e-1)" "unprognostic (1.07e-1)" "unprognostic (2.14e-3)" "potential prognostic unfavorable (5.41e-6)" "potential prognostic favorable (5.08e-5)" "unprognostic (2.90e-1)" "unprognostic (3.02e-2)" "validated prognostic unfavorable (6.60e-4)" "validated prognostic unfavorable (2.18e-4)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (3.72e-3)" "unprognostic (1.47e-1)" "unprognostic (1.37e-1)" "unprognostic (2.69e-2)" "unprognostic (4.95e-3)" "unprognostic (3.10e-2)" "unprognostic (3.34e-1)" "unprognostic (3.56e-2)" "unprognostic (8.87e-2)" "unprognostic (2.65e-2)" "unprognostic (5.29e-3)" "unprognostic (2.99e-1)" "unprognostic (2.83e-2)" "unprognostic (3.25e-2)" "unprognostic (1.91e-1)" PSMG1 "c21-LRP, DSCR2, LRPC21, PAC1" ENSG00000183527 "Proteasome assembly chaperone 1" O95456 21 39174769-39183488 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 37.6" "Cell type enhanced" "Detected in many" "Early spermatids: 539.1;Late primary spermatocytes: 1403.1;Oocytes: 350.0" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 1403.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cell types: 28470831.5" "Tissue enhanced" "Detected in many" "cerebral cortex: 24017251.7" "HPA057193, HPA070225" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" No No 6900 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 57: Testis - Spermatogenesis" "Cluster 29: Forebrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 57 "Nucleoplasm, Golgi apparatus, Cytosol" "HPA057193: , HPA070225: " "unprognostic (1.91e-1)" "unprognostic (3.16e-2)" "unprognostic (4.93e-1)" "unprognostic (5.40e-2)" "unprognostic (1.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.26e-1)" "unprognostic (6.56e-2)" "unprognostic (1.37e-2)" "unprognostic (5.70e-3)" "unprognostic (1.49e-2)" "unprognostic (1.69e-1)" "unprognostic (2.53e-1)" "unprognostic (1.53e-3)" "unprognostic (1.71e-3)" "unprognostic (8.03e-2)" "unprognostic (2.63e-1)" "unprognostic (4.66e-2)" "unprognostic (1.52e-2)" "unprognostic (5.38e-2)" "unprognostic (3.92e-1)" "unprognostic (2.66e-1)" "unprognostic (1.45e-1)" "unprognostic (1.60e-3)" "unprognostic (1.82e-2)" "unprognostic (1.32e-2)" "unprognostic (8.74e-3)" "unprognostic (7.06e-2)" "unprognostic (2.20e-1)" "unprognostic (1.01e-1)" "unprognostic (1.70e-1)" PSMG4 "C6orf86, PAC4" ENSG00000180822 "Proteasome assembly chaperone 4" Q5JS54 6 3231403-3303373 "Essential proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Oocytes: 529.6" "Cell type enriched" "Detected in all" 4 "Oocytes: 529.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 1029569.5" "Tissue enhanced" "Detected in many" "liver: 917753.6" "HPA067652, HPA074376, HPA075846" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 24: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 30 "Nucleoplasm, Mitochondria" "HPA067652: , HPA074376: , HPA075846: " "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.49e-3)" "unprognostic (2.86e-1)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.34e-1)" "unprognostic (1.88e-3)" "unprognostic (1.77e-1)" "unprognostic (7.82e-3)" "unprognostic (1.94e-2)" "unprognostic (2.32e-1)" "unprognostic (5.71e-3)" "potential prognostic unfavorable (4.59e-4)" "unprognostic (5.49e-2)" "unprognostic (1.30e-1)" "unprognostic (1.21e-1)" "unprognostic (4.32e-2)" "unprognostic (7.90e-2)" "unprognostic (4.19e-2)" "unprognostic (9.78e-2)" "unprognostic (9.19e-3)" "unprognostic (2.22e-1)" "unprognostic (2.34e-1)" "unprognostic (5.81e-2)" "unprognostic (2.80e-2)" "unprognostic (2.87e-1)" "unprognostic (1.93e-1)" "unprognostic (3.96e-2)" "unprognostic (3.55e-1)" "unprognostic (1.93e-1)" PSPC1 "FLJ10955, PSP1" ENSG00000121390 "Paraspeckle component 1" Q8WXF1 13 19674752-19783019 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 159320964.5" "Low tissue specificity" "Detected in all" HPA038904 Supported Enhanced "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 328 Nucleoplasm "Nucleoli fibrillar center" "HPA038904: " "unprognostic (5.08e-2)" "unprognostic (1.70e-2)" "unprognostic (2.08e-1)" "unprognostic (2.64e-1)" "unprognostic (1.02e-1)" "unprognostic (2.69e-1)" "unprognostic (1.27e-1)" "potential prognostic favorable (7.32e-4)" "unprognostic (1.19e-1)" "unprognostic (5.61e-2)" "potential prognostic favorable (9.17e-4)" "unprognostic (1.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.36e-3)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (1.40e-3)" "unprognostic (2.11e-3)" "unprognostic (3.75e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (5.22e-4)" "unprognostic (3.71e-2)" "unprognostic (6.24e-2)" "unprognostic (1.55e-1)" "unprognostic (2.15e-1)" "unprognostic (2.93e-2)" "unprognostic (3.58e-1)" "unprognostic (4.92e-2)" "unprognostic (2.63e-1)" PSTK "C10orf89, MGC35392" ENSG00000179988 "Phosphoseryl-tRNA kinase" Q8IV42 10 122954381-122997513 "Enzymes, Predicted intracellular proteins" "Protein biosynthesis" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 87.6;Oocytes: 124.3" "Cell type enhanced" "Detected in many" "Oocytes: 124.3;Spermatogenic cell types: 87.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1863 "Oocytes: 186264.8" "Not detected" "Not detected" "HPA037780, HPA037781" Approved Approved "Nucleoli,Nuclear bodies,Actin filaments" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 1 "Actin filaments" "Nucleoli, Nuclear bodies" "HPA037780: , HPA037781: " "unprognostic (1.39e-2)" "unprognostic (1.17e-1)" "unprognostic (8.10e-2)" "unprognostic (1.18e-3)" "unprognostic (7.07e-2)" "unprognostic (1.39e-1)" "unprognostic (1.17e-1)" "unprognostic (8.67e-3)" "unprognostic (8.48e-2)" "unprognostic (4.90e-2)" "unprognostic (4.07e-2)" "unprognostic (3.06e-1)" "unprognostic (2.98e-1)" "unprognostic (1.13e-1)" "unprognostic (4.25e-3)" "unprognostic (1.80e-1)" "unprognostic (3.84e-2)" "unprognostic (6.41e-2)" "unprognostic (3.26e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (2.03e-2)" "unprognostic (2.47e-2)" "unprognostic (1.59e-2)" "unprognostic (6.23e-3)" "unprognostic (6.86e-2)" "unprognostic (1.70e-1)" "unprognostic (1.54e-1)" "unprognostic (1.50e-3)" "unprognostic (1.46e-2)" PTCH1 "BCNS, NBCCS, PTCH" ENSG00000185920 "Patched 1" Q13635 9 95442980-95517057 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant, Holoprosencephaly, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 34.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 406.1;Endometrial stromal cells: 132.7;Late spermatids: 423.0;Leydig cells: 386.2;Peritubular myoid cells: 686.1" "Group enriched" "Detected in many" 4 "Glial cells: 406.1;Leydig cells: 386.2;Spermatogenic cell types: 423.0;Stromal cells: 686.1" "Cell type enhanced" "Detected in all" "Bergmann glia: 439.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 6.2" "Lineage enriched" "Detected in single" 9 "T-cells: 6.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 912 "Stomach: 91202.8" "CAB013717, HPA075072" Uncertain Approved "Golgi apparatus,Primary cilium" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 13: Lung - Secretion" "Cluster 46: Brainstem - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 16 "Golgi apparatus" "Primary cilium" "CAB013717: , HPA075072: " "unprognostic (7.06e-2)" "unprognostic (1.01e-1)" "unprognostic (4.69e-2)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (2.33e-2)" "unprognostic (7.23e-2)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (3.23e-1)" "potential prognostic favorable (4.44e-7)" "unprognostic (2.91e-3)" "unprognostic (2.84e-1)" "unprognostic (2.17e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (1.96e-1)" "potential prognostic favorable (8.18e-5)" "unprognostic (1.25e-2)" "unprognostic (1.94e-1)" "unprognostic (3.85e-2)" "unprognostic (6.44e-2)" "unprognostic (9.19e-2)" "unprognostic (7.93e-3)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (9.31e-2)" "unprognostic (5.07e-2)" "unprognostic (8.53e-2)" "unprognostic (4.11e-3)" PTGES "MGST-IV, MGST1-L1, MGST1L1, PIG12, TP53I12" ENSG00000148344 "Prostaglandin E synthase" O14684 9 129738331-129753042 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Isomerase, Oxidoreductase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 79.5;urinary bladder: 73.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 144.4;Endometrial secretory cells: 73.9;Extravillous trophoblasts: 406.2;Migrating cytotrophoblasts: 326.9;Ocular epithelial cells: 120.5;Salivary duct cells: 118.5;Syncytiotrophoblasts: 317.6" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 120.5;Ductal cells: 118.5;Trophoblast cells: 406.2" "Cell type enriched" "Detected in some" 12 "endothelial cell: 25.0" "Cancer enhanced" "Detected in all" "Bladder Urothelial Carcinoma (TCGA): 121.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "basophil: 29.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 29.0" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 7080382.4;T-cells: 4604679.5" "Tissue enhanced" "Detected in many" "skin: 20760657.0" HPA045064 Enhanced Supported "Endoplasmic reticulum" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 15 "Endoplasmic reticulum" "HPA045064: " "unprognostic (1.21e-2)" "unprognostic (6.20e-2)" "unprognostic (3.30e-1)" "unprognostic (2.97e-1)" "unprognostic (2.11e-2)" "unprognostic (7.99e-2)" "potential prognostic unfavorable (5.31e-4)" "unprognostic (5.44e-3)" "unprognostic (5.71e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (3.42e-5)" "unprognostic (2.16e-2)" "unprognostic (2.00e-1)" "unprognostic (4.64e-3)" "unprognostic (7.48e-3)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (3.28e-2)" "unprognostic (1.80e-2)" "unprognostic (1.64e-1)" "unprognostic (1.49e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (4.14e-3)" "unprognostic (2.40e-1)" "unprognostic (2.87e-2)" "unprognostic (4.23e-2)" "unprognostic (4.90e-2)" "unprognostic (1.17e-1)" "unprognostic (1.00e-1)" "unprognostic (1.61e-1)" "unprognostic (1.11e-1)" PTGES3 "cPGES, p23, TEBP" ENSG00000110958 "Prostaglandin E synthase 3" Q15185 12 56663341-56688408 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism, Prostaglandin biosynthesis, Prostaglandin metabolism" "Chaperone, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB034319, HPA038672, HPA038673" Enhanced Approved Nucleoplasm,Cytosol NA NA 1300000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 75: Non-specific - Chaperones and protein folding" 201 Cytosol Nucleoplasm "CAB034319: , HPA038672: , HPA038673: " "unprognostic (3.39e-2)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (1.17e-3)" "unprognostic (6.05e-3)" "unprognostic (7.34e-3)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (2.74e-3)" "unprognostic (5.45e-3)" "unprognostic (2.09e-2)" "potential prognostic favorable (1.14e-6)" "unprognostic (2.77e-2)" "unprognostic (2.96e-2)" "validated prognostic unfavorable (1.12e-4)" "validated prognostic unfavorable (6.54e-7)" "potential prognostic unfavorable (5.52e-5)" "unprognostic (1.91e-3)" "unprognostic (1.13e-1)" "unprognostic (1.26e-1)" "unprognostic (1.02e-1)" "unprognostic (2.51e-3)" "unprognostic (3.59e-3)" "unprognostic (1.83e-2)" "unprognostic (1.26e-3)" "unprognostic (7.87e-2)" "unprognostic (2.28e-2)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (2.81e-1)" "unprognostic (1.20e-1)" "unprognostic (4.77e-2)" PTGR3 "MGC45594, PTGR-3, ZADH2" ENSG00000180011 "Prostaglandin reductase 3" Q8N4Q0 18 75195113-75209139 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubules: 21066260.6" "Low tissue specificity" "Detected in many" "HPA021468, HPA053646" Uncertain Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 108: Fibroblasts - ECM organization" 8 Vesicles "Nucleoplasm, Golgi apparatus" "HPA021468: , HPA053646: " "unprognostic (4.72e-1)" "unprognostic (3.25e-2)" "unprognostic (3.84e-1)" "unprognostic (2.29e-1)" "unprognostic (7.22e-2)" "unprognostic (1.45e-1)" "unprognostic (2.32e-1)" "unprognostic (1.49e-3)" "unprognostic (2.00e-2)" "unprognostic (1.54e-1)" "validated prognostic favorable (3.82e-6)" "validated prognostic favorable (7.88e-5)" "unprognostic (1.70e-2)" "unprognostic (9.51e-2)" "unprognostic (2.69e-1)" "unprognostic (2.21e-1)" "unprognostic (1.56e-1)" "unprognostic (4.06e-1)" "unprognostic (2.26e-1)" "unprognostic (9.87e-2)" "unprognostic (2.65e-1)" "unprognostic (5.87e-2)" "unprognostic (7.45e-2)" "unprognostic (5.39e-2)" "unprognostic (1.29e-1)" "unprognostic (4.53e-2)" "unprognostic (2.94e-3)" "unprognostic (1.88e-1)" "unprognostic (1.37e-1)" "unprognostic (1.39e-3)" "unprognostic (2.69e-1)" PTK2 "FADK, FAK, FAK1, PPP1R71" ENSG00000169398 "Protein tyrosine kinase 2" Q05397 8 140657900-141002216 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 1291.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA001842, CAB004036, HPA029671" Approved Supported "Vesicles,Focal adhesion sites,Primary cilium,Primary cilium tip,Cytosol" NA Yes 4600 "Cluster 34: B-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 110 "Focal adhesion sites" "Vesicles, Primary cilium, Primary cilium tip, Cytosol" "CAB004036: , HPA001842: , HPA029671: " "unprognostic (1.35e-1)" "potential prognostic unfavorable (9.28e-4)" "unprognostic (1.49e-1)" "unprognostic (5.54e-3)" "unprognostic (1.29e-1)" "unprognostic (5.58e-3)" "unprognostic (1.61e-1)" "unprognostic (1.19e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.25e-5)" "validated prognostic favorable (2.39e-5)" "validated prognostic favorable (1.27e-4)" "unprognostic (1.97e-2)" "unprognostic (2.98e-2)" "unprognostic (1.81e-2)" "unprognostic (1.19e-1)" "unprognostic (3.19e-2)" "unprognostic (5.09e-2)" "unprognostic (2.21e-1)" "unprognostic (9.65e-2)" "unprognostic (2.62e-1)" "unprognostic (3.61e-2)" "potential prognostic unfavorable (7.77e-5)" "unprognostic (5.46e-1)" "unprognostic (7.22e-2)" "unprognostic (1.79e-1)" "unprognostic (2.11e-1)" "unprognostic (2.13e-2)" "unprognostic (6.75e-2)" "unprognostic (3.12e-1)" "unprognostic (7.90e-2)" PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 104.2;skin 1: 51.4;vagina: 41.0" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 774.1" "Cell type enriched" "Detected in many" 4 "Apical squamous epithelial cells: 774.1" "Cell type enhanced" "Detected in single" "oligodendrocyte: 2.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 34.3" "Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 40248 "Keratinocytes: 4024789.9" "Tissue enriched" "Detected in some" "Stomach: 499743.0" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 41 Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: , HPA036070: , HPA036071: " "potential prognostic favorable (3.07e-4)" "unprognostic (7.89e-3)" "unprognostic (1.21e-1)" "unprognostic (1.82e-2)" "unprognostic (1.34e-1)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "potential prognostic unfavorable (7.01e-8)" "unprognostic (2.01e-2)" "unprognostic (1.92e-1)" "unprognostic (1.26e-1)" "unprognostic (8.62e-2)" "unprognostic (2.96e-1)" "unprognostic (5.11e-2)" "unprognostic (1.43e-2)" "unprognostic (1.59e-2)" "unprognostic (4.69e-2)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (2.73e-4)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-1)" "unprognostic (1.56e-1)" "unprognostic (3.75e-2)" "unprognostic (1.83e-2)" "unprognostic (1.61e-1)" PTMA TMSA ENSG00000187514 "Prothymosin alpha" P06454 2 231706895-231713551 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 1603546.4;Neutrophils: 1646115.5" "Tissue enhanced" "Detected in all" "ovary: 197533644.2" HPA047183 Approved Enhanced Nucleoplasm,Cytosol No No 4700000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 15: Non-specific - Protein processing" 38 Nucleoplasm Cytosol "HPA047183: " "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" "unprognostic (1.89e-1)" "unprognostic (5.21e-3)" "unprognostic (1.15e-1)" "unprognostic (9.09e-2)" "unprognostic (5.16e-3)" "unprognostic (1.03e-3)" "unprognostic (3.45e-2)" "unprognostic (4.39e-2)" "unprognostic (2.60e-1)" "unprognostic (3.42e-2)" "unprognostic (1.13e-2)" "validated prognostic unfavorable (2.49e-5)" "validated prognostic unfavorable (3.07e-5)" "unprognostic (1.02e-2)" "unprognostic (1.10e-2)" "unprognostic (5.95e-2)" "unprognostic (3.33e-1)" "unprognostic (2.57e-2)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (8.53e-4)" "unprognostic (6.18e-2)" "unprognostic (4.23e-2)" "unprognostic (1.10e-1)" "unprognostic (3.28e-2)" "unprognostic (5.99e-2)" "unprognostic (8.57e-2)" "unprognostic (1.48e-1)" "unprognostic (1.29e-1)" "unprognostic (2.25e-1)" PTMS ParaT ENSG00000159335 Parathymosin P20962 12 6765516-6770952 "Essential proteins, Predicted intracellular proteins" Immunity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 760.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 742.8;Hofbauer cells: 876.3;Megakaryocytes: 605.8;Peritubular myoid cells: 615.6;Smooth muscle cells: 619.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 25.8" "Lineage enriched" "Detected in many" 6 "granulocytes: 25.8" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Alveolar cell types: 1936958.3;Hepatocytes: 2409069.6;Keratinocytes: 6336483.6;Oocytes: 1654895.2;Smooth muscle cells: 3912767.3" "Group enriched" "Detected in all" "kidney: 75751498.9;liver: 209273560.3;ovary: 283535444.9;skin: 72010585.1" HPA038186 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No Yes 1600000 "Cluster 22: Eosinophils - Transcription" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 33: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 4 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA038186: " "unprognostic (5.52e-2)" "unprognostic (1.54e-2)" "unprognostic (5.69e-2)" "unprognostic (7.56e-2)" "unprognostic (1.43e-1)" "unprognostic (8.58e-2)" "unprognostic (1.47e-1)" "unprognostic (6.92e-3)" "unprognostic (6.18e-2)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "unprognostic (4.62e-2)" "unprognostic (1.20e-2)" "unprognostic (1.45e-1)" "unprognostic (2.78e-1)" "unprognostic (2.13e-1)" "unprognostic (3.11e-1)" "unprognostic (1.14e-1)" "unprognostic (8.34e-2)" "unprognostic (8.48e-2)" "unprognostic (3.89e-2)" "unprognostic (2.19e-3)" "unprognostic (3.65e-2)" "unprognostic (1.94e-1)" "unprognostic (1.00e-2)" "unprognostic (2.29e-1)" "unprognostic (4.53e-1)" "unprognostic (1.34e-1)" "unprognostic (9.69e-2)" "unprognostic (1.64e-2)" "unprognostic (6.76e-2)" PTOV1 ENSG00000104960 "PTOV1 extended AT-hook containing adaptor protein" Q86YD1 19 49850735-49860744 "Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 386.7;Late spermatids: 1068.1" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 1068.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 445707.0" "Not detected" "Not detected" "HPA051812, HPA075125" Approved Supported Nucleoplasm NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 21 Nucleoplasm "HPA051812: , HPA075125: " "unprognostic (4.25e-2)" "unprognostic (3.18e-1)" "unprognostic (8.82e-2)" "unprognostic (1.69e-1)" "unprognostic (3.29e-1)" "unprognostic (4.15e-2)" "unprognostic (1.60e-1)" "unprognostic (1.18e-1)" "unprognostic (2.13e-1)" "unprognostic (2.27e-1)" "unprognostic (5.24e-2)" "unprognostic (5.12e-2)" "unprognostic (3.10e-3)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.30e-1)" "unprognostic (1.46e-2)" "unprognostic (2.28e-1)" "unprognostic (4.06e-1)" "unprognostic (3.44e-1)" "unprognostic (9.08e-2)" "unprognostic (1.20e-1)" "unprognostic (8.17e-3)" "unprognostic (2.34e-3)" "unprognostic (1.15e-1)" "unprognostic (2.59e-1)" "unprognostic (9.67e-2)" "unprognostic (2.72e-1)" "unprognostic (1.68e-1)" "unprognostic (7.38e-3)" "unprognostic (1.34e-1)" "unprognostic (1.60e-1)" PTPMT1 "DUSP23, MOSP, PLIP" ENSG00000110536 "Protein tyrosine phosphatase mitochondrial 1" Q8WUK0 11 47565430-47573461 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 170.9;Late primary spermatocytes: 269.0;Late spermatids: 849.5" "Cell type enriched" "Detected in many" 20 "Spermatogenic cell types: 849.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 7445992.0" "Tissue enhanced" "Detected in many" "cerebral cortex: 850003.8;fallopian tube: 963751.7" "HPA043932, HPA060060" Approved Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 31 Mitochondria "HPA043932: , HPA060060: " "unprognostic (2.49e-2)" "unprognostic (1.13e-2)" "unprognostic (3.34e-2)" "unprognostic (2.84e-1)" "unprognostic (2.17e-1)" "unprognostic (1.10e-1)" "unprognostic (2.75e-2)" "unprognostic (1.27e-1)" "unprognostic (2.93e-2)" "unprognostic (2.61e-2)" "unprognostic (2.61e-2)" "unprognostic (3.23e-2)" "unprognostic (4.40e-1)" "validated prognostic unfavorable (2.42e-4)" "validated prognostic unfavorable (4.91e-4)" "unprognostic (2.21e-1)" "unprognostic (2.30e-2)" "unprognostic (1.89e-1)" "unprognostic (9.28e-2)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (1.03e-1)" "unprognostic (2.08e-1)" "unprognostic (9.66e-3)" "unprognostic (1.55e-1)" "unprognostic (6.67e-2)" "unprognostic (1.29e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (2.37e-2)" "unprognostic (3.41e-1)" PTPN11 "BPTP3, NS1, PTP2C, SH-PTP2, SHP-2, SHP2" ENSG00000179295 "Protein tyrosine phosphatase non-receptor type 11" Q06124 12 112418351-112509918 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 126629635.6" CAB005377 Approved Supported "Nucleoplasm,Nucleoli rim,Actin filaments,Cytosol" NA NA 100000 "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 131 "Nucleoli rim" "Nucleoplasm, Actin filaments, Cytosol" "CAB005377: " "unprognostic (1.43e-1)" "unprognostic (6.88e-3)" "unprognostic (2.42e-1)" "unprognostic (1.08e-2)" "unprognostic (3.63e-1)" "unprognostic (9.85e-2)" "unprognostic (6.21e-2)" "unprognostic (7.02e-2)" "unprognostic (1.06e-1)" "unprognostic (3.57e-2)" "potential prognostic favorable (8.07e-4)" "unprognostic (4.22e-2)" "unprognostic (1.55e-1)" "unprognostic (2.85e-2)" "unprognostic (5.69e-2)" "unprognostic (2.00e-2)" "unprognostic (3.78e-3)" "unprognostic (5.37e-2)" "unprognostic (1.76e-1)" "unprognostic (5.19e-2)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (3.55e-2)" "unprognostic (3.66e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-2)" "unprognostic (8.12e-3)" "unprognostic (1.43e-1)" "unprognostic (1.39e-1)" "unprognostic (8.63e-2)" "unprognostic (3.56e-2)" "unprognostic (1.39e-1)" PTPN13 "PTP-BAS, PTP-BL, PTP1E, PTPL1" ENSG00000163629 "Protein tyrosine phosphatase non-receptor type 13" Q12923 4 86594315-86815171 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 115.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 877.7;Ocular epithelial cells: 1473.7;Podocytes: 1754.6;Renal connecting tubule cells: 786.2;Retinal pigment epithelial cells: 1381.2;Rod photoreceptor cells: 1490.4" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 1473.7;Neuronal cells: 1490.4;Pigment cells: 1381.2;Renal nephron cells: 1754.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Liver - Hepatic stellate cells, Lung - Alveolar cells type 2, Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 23298659.9;Keratinocytes: 23946698.0;Microglia and Neuropil: 24536293.8" "Low tissue specificity" "Detected in many" "CAB002213, HPA065290" Approved Approved "Plasma membrane,Primary cilium,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 42: Retina - Visual perception" "Cluster 55: Non-specific - Transcription" "Cluster 1: Neuronal - Visual perception" "Cluster 100: Stratified epithelial cells - Barrier functions" 33 "Plasma membrane, Primary cilium" "Primary cilium transition zone, Basal body, Cytosol" "CAB002213: , HPA065290: " "unprognostic (6.40e-3)" "unprognostic (2.37e-2)" "unprognostic (1.40e-1)" "unprognostic (9.20e-2)" "unprognostic (2.39e-1)" "unprognostic (1.64e-2)" "unprognostic (1.85e-1)" "unprognostic (5.34e-1)" "unprognostic (7.81e-3)" "unprognostic (9.60e-2)" "validated prognostic favorable (2.43e-6)" "validated prognostic favorable (4.91e-4)" "unprognostic (2.46e-1)" "unprognostic (1.28e-1)" "unprognostic (7.18e-2)" "unprognostic (2.12e-1)" "unprognostic (2.61e-1)" "unprognostic (1.33e-1)" "unprognostic (2.62e-2)" "unprognostic (2.96e-1)" "unprognostic (2.12e-2)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.40e-1)" "unprognostic (3.19e-1)" "unprognostic (3.55e-1)" "unprognostic (2.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.00e-1)" "unprognostic (6.05e-2)" PTPN18 BDP1 ENSG00000072135 "Protein tyrosine phosphatase non-receptor type 18" Q99952 2 130356045-130375405 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Platelets: 1048.0;Tuft cells: 657.1" "Group enriched" "Detected in all" 4 "Platelets: 1048.0;Secretory gland support: 657.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 3595 "Neutrophils: 359507.3" "Tissue enriched" "Detected in many" "blood vessel: 41072322.5" "CAB012174, HPA053367" Uncertain Approved "Intermediate filaments" NA NA 380000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 5: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 47: Platelets - Hemostasis" 11 "Intermediate filaments" "CAB012174: , HPA053367: " "unprognostic (2.82e-2)" "unprognostic (7.80e-2)" "unprognostic (1.97e-2)" "unprognostic (6.97e-2)" "unprognostic (8.83e-3)" "unprognostic (3.90e-3)" "unprognostic (3.59e-3)" "unprognostic (2.04e-1)" "unprognostic (4.97e-3)" "unprognostic (1.78e-2)" "unprognostic (2.48e-3)" "unprognostic (2.55e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (8.46e-2)" "unprognostic (1.26e-2)" "unprognostic (1.20e-1)" "unprognostic (8.07e-2)" "unprognostic (1.42e-1)" "unprognostic (6.28e-2)" "unprognostic (7.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.38e-1)" "unprognostic (1.01e-1)" "unprognostic (3.09e-1)" "unprognostic (2.49e-2)" "unprognostic (5.79e-3)" "unprognostic (3.49e-1)" "unprognostic (1.93e-3)" "unprognostic (3.30e-1)" "unprognostic (1.27e-1)" "unprognostic (2.50e-1)" PTPN23 "DKFZP564F0923, HD-PTP, KIAA1471" ENSG00000076201 "Protein tyrosine phosphatase non-receptor type 23" Q9H3S7 3 47381011-47413435 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 33883642.5" HPA016845 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles,Centriolar satellite,Basal body,Cytosol,Calyx,Mid piece" Yes No "Cluster 32: Basophils - Transcription" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 44 "Nucleoplasm, Nuclear bodies, Basal body" "Vesicles, Centriolar satellite, Cytosol, Calyx, Mid piece" "HPA016845: " "unprognostic (4.22e-2)" "unprognostic (7.52e-2)" "unprognostic (2.36e-1)" "unprognostic (1.05e-1)" "unprognostic (3.10e-1)" "unprognostic (9.72e-2)" "unprognostic (1.21e-1)" "unprognostic (5.26e-2)" "unprognostic (2.61e-3)" "unprognostic (1.80e-2)" "potential prognostic favorable (9.75e-5)" "unprognostic (8.96e-2)" "unprognostic (3.36e-2)" "unprognostic (1.38e-1)" "unprognostic (1.99e-3)" "unprognostic (5.18e-2)" "unprognostic (2.69e-2)" "unprognostic (2.99e-2)" "unprognostic (5.10e-2)" "unprognostic (1.44e-1)" "unprognostic (3.33e-1)" "unprognostic (2.25e-1)" "unprognostic (3.53e-2)" "unprognostic (1.91e-1)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (6.22e-3)" "unprognostic (7.31e-2)" "unprognostic (3.39e-1)" "unprognostic (3.94e-2)" "unprognostic (3.61e-2)" PTPN7 "HEPTP, LC-PTP" ENSG00000143851 "Protein tyrosine phosphatase non-receptor type 7" P35236 1 202147013-202161588 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 64.9;lymphoid tissue: 71.0" "Cell type enhanced" "Detected in many" "B-cells: 44.0;Erythrocyte progenitors: 47.2;Hematopoietic stem cells: 54.8;Innate lymphoid cells: 97.3;Mast cells: 108.9;Megakaryocyte progenitors: 64.7;Megakaryocyte-Erythroid progenitors: 53.0;Monocyte progenitors: 43.1;Neutrophil progenitors: 118.2;Neutrophils: 60.3;NK-cells: 127.0;Podocytes: 51.1;Sertoli cells: 79.4;T-cells: 121.9;Thymocytes: 45.7" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 97.3;Mast cells: 108.9;Neutrophils: 118.2;NK-cells: 127.0;T-cells: 121.9" "Cell type enhanced" "Detected in many" "leukocyte: 105.7;medium spiny neuron: 55.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "granulocytes: 35.6;NK-cells: 39.9;T-cells: 46.5" "Group enriched" "Detected in some" 32 "Leukemia: 132.2;lymphoma: 66.1;Myeloma: 52.7" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - T-cells, Liver - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Testis - Sertoli cells, Thyroid gland - T-cells" "Region enriched" "Detected in single" 9 "basal ganglia: 6.1" "Region enriched" "Detected in single" 17 "basal ganglia: 16.5" "Group enriched" "Detected in some" "B-cells: 2332221.6;T-cells: 5591523.2" "Tissue enriched" "Detected in some" "lymphoid tissue: 3065023.0" "CAB009530, HPA019118" Approved Supported "Microtubules,Mitotic spindle,Cytosol" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 33: Neurons - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 9 Cytosol "Microtubules, Mitotic spindle" "CAB009530: , HPA019118: " "unprognostic (5.55e-2)" "unprognostic (3.04e-3)" "unprognostic (9.08e-3)" "unprognostic (2.27e-3)" "unprognostic (1.46e-1)" "unprognostic (5.49e-2)" "unprognostic (3.16e-2)" "unprognostic (1.65e-1)" "potential prognostic favorable (1.03e-4)" "unprognostic (1.19e-3)" "unprognostic (6.32e-2)" "unprognostic (2.45e-2)" "unprognostic (3.96e-2)" "unprognostic (1.63e-2)" "unprognostic (8.07e-2)" "unprognostic (1.52e-1)" "unprognostic (3.03e-1)" "unprognostic (7.13e-2)" "unprognostic (2.64e-2)" "unprognostic (2.64e-2)" "unprognostic (2.25e-2)" "unprognostic (3.00e-2)" "unprognostic (7.76e-3)" "unprognostic (2.05e-1)" "unprognostic (2.28e-1)" "unprognostic (4.02e-1)" PTPRC "CD45, GP180, LCA, T200" ENSG00000081237 "Protein tyrosine phosphatase receptor type C" P08575 1 198638457-198757476 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Hydrolase, Protein phosphatase" "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 273.8" "Cell type enriched" "Detected in many" 4 "Neutrophils: 4182.4" "Cell type enriched" "Detected in many" 4 "Neutrophils: 4182.4" "Group enriched" "Detected in many" 14 "central nervous system macrophage: 1145.9;leukocyte: 3019.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Leukemia: 84.8;lymphoma: 127.0" "Adipose visceral - T-cells, Adrenal gland - Macrophages, Breast - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Prostate - T-cells, Skin - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 80105965.1;Macrophages: 97636871.2;Neutrophils: 77064611.2;T-cells: 139781255.6" "Tissue enriched" "Detected in many" "lymphoid tissue: 171192495.2" "CAB000052, HPA000440, CAB002800, CAB056154, CAB068221, CAB080251" Enhanced Uncertain Nucleoplasm,Vesicles "Intracellular and membrane" Enzyme NA NA 6800000 "Cluster 28: Neutrophils - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 15 "Nucleoplasm, Vesicles" "CAB000052: , CAB002800: , CAB056154: , CAB068221: , CAB080251: , HPA000440: " "unprognostic (3.82e-2)" "unprognostic (6.75e-2)" "unprognostic (3.07e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.32e-1)" "unprognostic (2.78e-1)" "unprognostic (2.28e-1)" "unprognostic (2.30e-3)" "unprognostic (1.63e-1)" "unprognostic (1.44e-2)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (2.78e-1)" "unprognostic (2.11e-2)" "potential prognostic favorable (5.92e-5)" "unprognostic (1.53e-1)" "unprognostic (1.92e-1)" "unprognostic (3.83e-1)" "unprognostic (1.09e-1)" "unprognostic (8.12e-2)" "unprognostic (3.72e-2)" "potential prognostic unfavorable (9.56e-4)" "unprognostic (4.00e-1)" "unprognostic (1.21e-2)" "unprognostic (2.38e-1)" "unprognostic (7.78e-2)" "unprognostic (1.61e-1)" "unprognostic (6.66e-2)" "unprognostic (2.48e-1)" "unprognostic (3.35e-1)" PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 229.4;Brain excitatory neurons: 404.3;Brain inhibitory neurons: 254.2;Choroid plexus epithelial cells: 333.4;Distal convoluted tubule cells: 314.4;Ependymal cells: 554.5;Loop of henle epithelial cells: 371.3;Oligodendrocyte progenitor cells: 469.8;Oligodendrocytes: 1524.9;Papillary tip epithelial cells: 531.1;Proximal tubule cells: 622.3;Renal collecting duct intercalated cells: 518.8;Renal collecting duct principal cells: 475.6;Renal connecting tubule cells: 434.8" "Group enriched" "Detected in many" 4 "Ciliated cells: 554.5;Ductal cells: 518.8;Glial cells: 1524.9;Neuronal cells: 404.3;Renal nephron cells: 622.3" "Cell type enhanced" "Detected in all" "pericyte: 3521.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 4234427.7" "Low tissue specificity" "Detected in many" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions,Connecting piece,Flagellar centriole" NA NA 4800000 "Cluster 18: Non-specific - Translation" "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 22: Non-specific - Basic cellular functions" 10 "Cell Junctions" "Vesicles, Plasma membrane, Connecting piece, Flagellar centriole" "HPA054056: , HPA054822: " "unprognostic (7.09e-2)" "unprognostic (2.33e-1)" "unprognostic (2.49e-1)" "unprognostic (3.10e-2)" "unprognostic (4.87e-3)" "unprognostic (2.23e-2)" "unprognostic (1.07e-1)" "unprognostic (2.14e-2)" "unprognostic (8.02e-2)" "unprognostic (6.36e-2)" "validated prognostic favorable (5.57e-9)" "validated prognostic favorable (9.10e-5)" "unprognostic (2.55e-1)" "unprognostic (5.64e-1)" "unprognostic (5.82e-3)" "unprognostic (1.23e-1)" "unprognostic (1.68e-2)" "unprognostic (9.56e-2)" "unprognostic (5.09e-2)" "unprognostic (7.76e-3)" "unprognostic (1.15e-3)" "potential prognostic unfavorable (3.10e-4)" "unprognostic (1.49e-1)" "unprognostic (3.71e-1)" "unprognostic (2.81e-3)" "unprognostic (2.99e-1)" "unprognostic (9.52e-2)" "unprognostic (9.47e-2)" "unprognostic (1.78e-1)" "unprognostic (2.58e-1)" "unprognostic (8.51e-3)" PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 1139.2;Choroid plexus epithelial cells: 1448.8;Endometrial glandular cells: 1120.2;Endometrial luminal cells: 1179.2;Melanocytes: 1194.2;Urothelial cells: 1106.6;Vascular endothelial cells: 1535.2" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 1825.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1941123.7" "Tissue enhanced" "Detected in many" "liver: 28478445.4" "HPA003891, CAB022442, CAB022443" Supported Enhanced "Plasma membrane,Primary cilium,Primary cilium tip" NA Yes 17000000 "Cluster 30: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 38: Sub-cortical - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 3 "Plasma membrane" "Primary cilium, Primary cilium tip" "CAB022442: , CAB022443: , HPA003891: " "unprognostic (2.99e-3)" "unprognostic (1.85e-1)" "unprognostic (2.03e-1)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (8.76e-2)" "unprognostic (3.26e-2)" "unprognostic (1.83e-1)" "unprognostic (7.55e-3)" "unprognostic (2.19e-1)" "unprognostic (4.95e-2)" "validated prognostic favorable (1.92e-9)" "validated prognostic favorable (3.76e-5)" "unprognostic (7.14e-2)" "unprognostic (2.15e-1)" "potential prognostic favorable (6.55e-4)" "unprognostic (2.44e-1)" "unprognostic (1.17e-1)" "unprognostic (4.61e-2)" "unprognostic (1.58e-1)" "unprognostic (8.29e-2)" "unprognostic (9.36e-2)" "unprognostic (4.17e-2)" "unprognostic (1.86e-2)" "unprognostic (7.57e-2)" "unprognostic (1.30e-1)" "unprognostic (2.33e-2)" "unprognostic (2.48e-1)" "unprognostic (1.31e-3)" "unprognostic (3.39e-2)" "unprognostic (1.79e-1)" "unprognostic (2.06e-1)" PTPRN2 "IA-2beta, ICAAR, KIAA0387, phogrin" ENSG00000155093 "Protein tyrosine phosphatase receptor type N2" Q92932 7 157539056-158587823 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Protein phosphatase, Receptor" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.1;pancreas: 92.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 608.0;Brain inhibitory neurons: 788.4;Corticotrophs: 491.7;Gonadotrophs: 910.6;Lactotrophs: 836.1;Neuroendocrine cells: 573.4;Other brain neurons: 691.5;Pancreatic islet cells: 538.8;Somatotrophs: 827.5;Thyrotrophs: 732.5" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 573.4;Neuronal cells: 788.4;Pancreatic islet cells: 538.8;Pituitary endocrine cells: 910.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 61.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 23.7" "Lineage enriched" "Detected in all" 4 "granulocytes: 23.7" "Cancer enhanced" "Detected in many" "thyroid cancer: 34.0" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Prostate - Prostate glandular cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 1764108.1;Pancreatic islets: 6167050.6" "Tissue enhanced" "Detected in some" "cerebral cortex: 11801667.6" "HPA006900, HPA007255, HPA026656" Enhanced Approved Vesicles NA NA 10000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 36: Brain & Liver - Signaling" "Cluster 51: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 Vesicles "HPA006900: , HPA007255: , HPA026656: " "unprognostic (3.40e-3)" "unprognostic (1.96e-1)" "unprognostic (4.84e-1)" "unprognostic (1.78e-1)" "unprognostic (1.85e-1)" "unprognostic (1.88e-3)" "potential prognostic unfavorable (8.03e-5)" "unprognostic (3.16e-1)" "unprognostic (7.66e-3)" "unprognostic (3.13e-3)" "potential prognostic favorable (2.46e-5)" "unprognostic (2.50e-2)" "unprognostic (1.11e-3)" "unprognostic (2.33e-1)" "potential prognostic favorable (4.13e-4)" "unprognostic (8.23e-2)" "unprognostic (4.34e-3)" "unprognostic (1.96e-2)" "unprognostic (4.28e-2)" "unprognostic (1.34e-1)" "unprognostic (1.27e-2)" "unprognostic (2.53e-2)" "unprognostic (1.51e-1)" "unprognostic (1.13e-1)" "unprognostic (4.32e-2)" "unprognostic (1.23e-2)" "unprognostic (7.74e-2)" "unprognostic (3.46e-3)" "unprognostic (3.04e-1)" PTPRQ DFNB84 ENSG00000139304 "Protein tyrosine phosphatase receptor type Q" 12 80402178-80680273 "Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "kidney: 7.8;urinary bladder: 4.6" "Cell type enriched" "Detected in many" 16 "Podocytes: 9487.7" "Cell type enriched" "Detected in many" 16 "Renal nephron cells: 9487.7" "Cell type enhanced" "Detected in many" "eccentric medium spiny neuron: 99.9;ependymal cell: 262.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 6.5" "Adipose visceral - Mesothelial cells, Kidney - Podocytes, Lung - Alveolar cells type 1, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA053245 Uncertain Approved Cytosol No NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 33: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 57: Podocytes - Glomerular filtration" Cytosol "HPA053245: " "potential prognostic unfavorable (8.09e-4)" PTPRZ1 "phosphacan, PTP18, PTPRZ, PTPZ, RPTPB" ENSG00000106278 "Protein tyrosine phosphatase receptor type Z1" P23471 7 121873089-122062036 "Enzymes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 150.5" "Cell type enhanced" "Detected in many" "Astrocytes: 981.3;Bergmann glia: 1581.8;Ependymal cells: 517.8;Oligodendrocyte progenitor cells: 3945.7;Respiratory basal cells: 456.9" "Cell type enriched" "Detected in many" 7 "Glial cells: 3945.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 1831.5;oligodendrocyte precursor cell: 4812.8" "Cancer enriched" "Detected in many" 17 "Glioblastoma Multiforme (TCGA): 591.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 21.7;skin cancer: 27.8" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 35451325.7;Keratinocytes: 25811467.0;Microglia and Neuropil: 29587015.0" "Tissue enhanced" "Detected in some" "cerebral cortex: 69281353.8;Stomach: 124605878.5" HPA015103 Enhanced Approved Vesicles,Cytosol "Secreted in brain" Enzyme NA NA 7400000 "Cluster 73: Brain - Neuronal signaling" "Cluster 21: Non-specific - Metabolism" "Cluster 69: Skin cancer - ECM organization" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 9 Cytosol Vesicles "HPA015103: " "unprognostic (2.48e-2)" "potential prognostic favorable (5.25e-6)" "unprognostic (1.42e-1)" "potential prognostic favorable (9.67e-4)" "unprognostic (1.62e-1)" "unprognostic (1.93e-2)" "unprognostic (3.28e-2)" "unprognostic (3.88e-3)" "unprognostic (4.53e-2)" "unprognostic (7.98e-2)" "unprognostic (5.94e-2)" "unprognostic (1.24e-3)" "unprognostic (1.08e-1)" "unprognostic (8.65e-2)" "unprognostic (3.20e-1)" "unprognostic (3.94e-1)" "unprognostic (2.13e-1)" PURG "PURG-A, PURG-B" ENSG00000172733 "Purine rich element binding protein G" Q9UJV8 8 30995802-31033715 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.2;retina: 4.0" "Cell type enhanced" "Detected in many" "Astrocytes: 89.1;Bergmann glia: 69.8;Brain excitatory neurons: 79.9;Brain inhibitory neurons: 80.7;Ependymal cells: 101.2;Lactotrophs: 79.3;Late spermatids: 33.2;Oligodendrocyte progenitor cells: 86.0;Oligodendrocytes: 42.0;Other brain neurons: 66.3;Pituicytes/FSCs: 75.2;Retinal amacrine cells: 49.0;Retinal ganglion cells: 46.4;Retinal horizontal cells: 52.1" "Group enriched" "Detected in many" 6 "Ciliated cells: 101.2;Glial cells: 89.1;Neuronal cells: 80.7;Pituitary endocrine cells: 79.3;Spermatogenic cell types: 33.2" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Glioblastoma Multiforme (TCGA): 4.8;Kidney Chromophobe (TCGA): 1.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 1.5;Testicular Germ Cell Tumor (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.5" "Colon - Enteric glia cells, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 6936568.2" "Tissue enriched" "Detected in single" 94313 "cerebral cortex: 9431330.8" HPA047746 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytokinetic bridge,Centrosome,Basal body" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 64 Nucleoplasm "Nucleoli, Plasma membrane, Cytokinetic bridge, Centrosome, Basal body" "HPA047746: " "unprognostic (1.30e-1)" "unprognostic (4.42e-2)" "unprognostic (2.42e-3)" "unprognostic (6.29e-2)" "unprognostic (1.38e-1)" "unprognostic (1.29e-1)" PUS10 "CCDC139, FLJ32312" ENSG00000162927 "Pseudouridine synthase 10" Q3MIT2 2 60940222-61018259 "Enzymes, Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 95.7;Epicardial cells: 295.6;Myonuclei: 93.0" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 295.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Hepatocytes: 8581200.3" "Tissue enriched" "Detected in single" 13335 "cerebral cortex: 1333525.0" "HPA044736, HPA049582" Approved Approved "Nucleoplasm,Nuclear bodies,Mitochondria" No No "Cluster 14: Non-specific - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 55: Non-specific - Transcription" "Cluster 55: Lymphoma - Immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 8 "Nucleoplasm, Nuclear bodies, Mitochondria" "HPA044736: , HPA049582: " "unprognostic (1.93e-1)" "unprognostic (6.03e-2)" "unprognostic (1.64e-1)" "unprognostic (1.10e-3)" "unprognostic (3.46e-1)" "unprognostic (8.51e-3)" "unprognostic (6.65e-2)" "unprognostic (1.24e-1)" "unprognostic (4.98e-2)" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (6.15e-2)" "unprognostic (1.31e-1)" "unprognostic (6.21e-2)" "unprognostic (7.11e-3)" "unprognostic (1.19e-3)" "unprognostic (2.72e-1)" "unprognostic (1.95e-1)" "unprognostic (1.10e-1)" "unprognostic (1.68e-1)" "potential prognostic unfavorable (5.05e-4)" "unprognostic (8.25e-2)" "unprognostic (7.22e-2)" "unprognostic (8.45e-2)" "unprognostic (4.00e-2)" "unprognostic (4.26e-2)" "unprognostic (1.00e-2)" "unprognostic (1.82e-1)" "unprognostic (1.36e-1)" "unprognostic (2.27e-1)" "unprognostic (1.85e-1)" PUSL1 FLJ90811 ENSG00000169972 "Pseudouridine synthase like 1" Q8N0Z8 1 1308597-1311677 "Predicted intracellular proteins" "tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 275.8" "Cell type enriched" "Detected in many" 4 "Apical squamous epithelial cells: 275.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Distal tubules: 1527790.9;Large ducts: 2925336.4" "Group enriched" "Detected in some" "fallopian tube: 607866.0;lymphoid tissue: 853826.8" "HPA032057, HPA039999" Uncertain Enhanced Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 4 Vesicles "HPA032057: , HPA039999: " "unprognostic (3.94e-3)" "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (9.18e-3)" "unprognostic (1.11e-1)" "unprognostic (3.35e-2)" "unprognostic (7.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.80e-1)" "unprognostic (7.63e-3)" "potential prognostic unfavorable (4.69e-7)" "unprognostic (9.87e-3)" "unprognostic (2.63e-1)" "validated prognostic unfavorable (2.07e-4)" "validated prognostic unfavorable (3.23e-6)" "unprognostic (9.45e-2)" "unprognostic (1.93e-1)" "unprognostic (4.15e-1)" "unprognostic (2.85e-1)" "unprognostic (2.36e-1)" "unprognostic (5.02e-2)" "unprognostic (6.62e-2)" "unprognostic (7.69e-2)" "unprognostic (2.40e-1)" "unprognostic (3.25e-1)" "unprognostic (1.75e-2)" "unprognostic (5.61e-2)" "unprognostic (2.04e-1)" "unprognostic (1.81e-1)" "unprognostic (3.15e-1)" "unprognostic (4.48e-2)" PWP1 IEF-SSP-9502 ENSG00000136045 "PWP1 homolog, endonuclein" Q13610 12 107685799-107713162 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA038708 Approved "Nucleoli rim,Golgi apparatus" Yes No "Cluster 14: Non-specific - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 19 "Nucleoli rim" "Golgi apparatus" "HPA038708: " "unprognostic (1.94e-2)" "unprognostic (1.02e-2)" "unprognostic (4.61e-2)" "unprognostic (7.13e-2)" "unprognostic (7.06e-2)" "unprognostic (2.50e-1)" "unprognostic (1.90e-1)" "unprognostic (3.81e-1)" "unprognostic (1.12e-3)" "unprognostic (1.49e-2)" "potential prognostic favorable (6.11e-5)" "unprognostic (1.27e-1)" "unprognostic (1.45e-3)" "validated prognostic unfavorable (5.29e-6)" "validated prognostic unfavorable (2.52e-4)" "potential prognostic unfavorable (2.42e-4)" "unprognostic (1.74e-3)" "unprognostic (4.34e-2)" "unprognostic (1.98e-2)" "unprognostic (1.32e-1)" "unprognostic (2.14e-2)" "unprognostic (7.90e-3)" "unprognostic (4.78e-3)" "unprognostic (2.62e-1)" "unprognostic (3.88e-3)" "unprognostic (5.66e-2)" "unprognostic (7.17e-2)" "unprognostic (1.18e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (2.74e-1)" PWP2 "EHOC-17, PWP2H, UTP1" ENSG00000241945 "PWP2 small subunit processome component" Q15269 21 44107373-44131181 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 4.9;Enteric stem cells: 4.9;Goblet cells: 4.1;Kupffer cells: 9.2;Megakaryocyte progenitors: 5.5" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 9.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 20209229.0" "Tissue enhanced" "Detected in many" "ovary: 4573178.5" HPA024573 Uncertain Supported Nucleoli,Cytosol NA NA 6800 "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 22 Nucleoli Cytosol "HPA024573: " "unprognostic (5.44e-2)" "unprognostic (1.45e-1)" "unprognostic (5.03e-2)" "unprognostic (2.10e-1)" "unprognostic (1.41e-1)" "unprognostic (8.89e-2)" "unprognostic (2.29e-1)" "unprognostic (1.77e-3)" "unprognostic (1.87e-1)" "unprognostic (3.39e-1)" "unprognostic (2.39e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (3.41e-1)" "unprognostic (2.67e-2)" "unprognostic (1.98e-1)" "unprognostic (3.42e-1)" "unprognostic (3.09e-1)" "unprognostic (1.47e-1)" "unprognostic (9.49e-3)" "unprognostic (2.51e-1)" "unprognostic (3.41e-2)" "unprognostic (8.71e-3)" "unprognostic (2.04e-1)" "unprognostic (2.62e-1)" "unprognostic (1.73e-1)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (4.01e-4)" "unprognostic (7.80e-2)" "unprognostic (1.14e-2)" "unprognostic (6.05e-2)" PYCR3 "FLJ13852, PYCRL" ENSG00000104524 "Pyrroline-5-carboxylate reductase 3" Q53H96 8 143603210-143609773 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Amino-acid biosynthesis, Proline biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 3.0;Bergmann glia: 3.1;Brain excitatory neurons: 5.2;Brain inhibitory neurons: 4.5;Choroid plexus epithelial cells: 2.4;Ependymal cells: 9.7;Loop of henle epithelial cells: 2.5;Oligodendrocyte progenitor cells: 2.2;Oligodendrocytes: 2.7;Other brain neurons: 4.9;Papillary tip epithelial cells: 2.6;Podocytes: 2.1;Proximal tubule cells: 3.1;Renal collecting duct principal cells: 2.9;Renal connecting tubule cells: 2.2" "Group enriched" "Detected in some" 5 "Ciliated cells: 9.7;Ductal cells: 2.9;Glial cells: 3.1;Neuronal cells: 5.2;Renal nephron cells: 3.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA053776, HPA063416, HPA069706" Uncertain Supported "Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 30 Cytosol "Cytokinetic bridge, Mitotic spindle" "HPA053776: , HPA063416: , HPA069706: " "unprognostic (1.10e-1)" "unprognostic (3.89e-2)" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.09e-2)" "unprognostic (3.28e-2)" "unprognostic (3.65e-2)" "unprognostic (3.12e-1)" "unprognostic (6.17e-2)" "potential prognostic unfavorable (2.86e-8)" "unprognostic (2.46e-2)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (2.52e-4)" "unprognostic (1.48e-2)" "unprognostic (5.95e-2)" "unprognostic (1.31e-2)" "unprognostic (3.03e-1)" "unprognostic (1.98e-3)" "unprognostic (2.19e-1)" "unprognostic (8.55e-3)" "unprognostic (1.20e-3)" "unprognostic (6.94e-3)" "unprognostic (3.20e-1)" "unprognostic (1.70e-1)" "unprognostic (8.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.38e-1)" "unprognostic (7.12e-2)" "unprognostic (1.19e-1)" PYGB ENSG00000100994 "Glycogen phosphorylase B" P11216 20 25248085-25298012 "Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 165.4;Lacrimal acinar cells: 170.3;Salivary basal cells: 187.8;Salivary duct cells: 282.6;Salivary ionocytes: 173.0;Smooth muscle cells: 174.5;Somatotrophs: 212.5" "Cell type enhanced" "Detected in many" "Ductal cells: 282.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells (progenitors), Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Large ducts: 735081522.9" "Low tissue specificity" "Detected in all" HPA031067 Approved Approved Cytosol NA NA 7500000 "Cluster 33: Non-specific - ATP binding" "Cluster 35: Non-specific - Mixed function" "Cluster 45: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 27 Cytosol "HPA031067: " "unprognostic (2.03e-1)" "unprognostic (2.21e-2)" "unprognostic (2.50e-1)" "unprognostic (3.44e-3)" "unprognostic (9.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.13e-1)" "unprognostic (2.98e-3)" "unprognostic (1.57e-2)" "unprognostic (4.60e-2)" "validated prognostic unfavorable (2.71e-4)" "validated prognostic unfavorable (1.58e-4)" "unprognostic (2.00e-1)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (5.49e-2)" "unprognostic (8.27e-3)" "unprognostic (3.25e-2)" "potential prognostic unfavorable (7.31e-5)" "unprognostic (1.38e-2)" "unprognostic (1.97e-3)" "unprognostic (6.91e-2)" "potential prognostic unfavorable (6.33e-4)" "unprognostic (1.45e-1)" "unprognostic (4.35e-1)" "unprognostic (1.96e-1)" "unprognostic (1.61e-1)" "unprognostic (7.37e-3)" "unprognostic (4.29e-2)" "unprognostic (2.73e-1)" "unprognostic (2.48e-1)" "unprognostic (1.57e-1)" PYGL GSD6 ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944483 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 136.2" "Cell type enhanced" "Detected in many" "Adipocytes: 307.4;Esophageal apical cells: 247.9;Extravillous trophoblasts: 218.8;Hofbauer cells: 436.6;Müller glia: 443.4;Neutrophil progenitors: 732.1;Neutrophils: 1659.3;Platelets: 280.7" "Cell type enhanced" "Detected in many" "Glial cells: 443.4;Mononuclear phagocytes: 436.6;Neutrophils: 1659.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 75.8;oligodendrocyte precursor cell: 59.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 141.4;neutrophil: 154.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Liver - Hepatocytes, Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Hepatocytes: 1228060132.0" "Tissue enriched" "Detected in all" "liver: 4150730183.8" "HPA000962, HPA004119" Enhanced Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 17 "Plasma membrane, Cytosol" "HPA000962: , HPA004119: " "unprognostic (8.64e-2)" "unprognostic (1.25e-2)" "unprognostic (1.08e-1)" "unprognostic (3.87e-3)" "unprognostic (5.03e-2)" "unprognostic (1.07e-2)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (9.63e-4)" "potential prognostic unfavorable (4.55e-4)" "unprognostic (3.21e-1)" "unprognostic (6.55e-3)" "unprognostic (1.22e-1)" "unprognostic (1.78e-1)" "unprognostic (2.28e-1)" "unprognostic (1.72e-1)" "validated prognostic unfavorable (2.16e-4)" "validated prognostic unfavorable (8.19e-4)" "unprognostic (2.72e-1)" "unprognostic (3.75e-2)" "unprognostic (7.51e-3)" "unprognostic (8.51e-2)" "potential prognostic unfavorable (5.93e-4)" "unprognostic (7.61e-3)" "unprognostic (7.64e-3)" "unprognostic (2.81e-2)" "unprognostic (1.44e-2)" "unprognostic (2.27e-1)" "unprognostic (1.58e-2)" "unprognostic (1.92e-1)" "unprognostic (7.89e-2)" "unprognostic (9.60e-2)" PYGO2 ENSG00000163348 "Pygopus family PHD finger 2" Q9BRQ0 1 154957026-154963853 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 396803.1;T-cells: 445468.4" "Tissue enriched" "Detected in many" "cerebral cortex: 5256553.4" "HPA023689, HPA074813" Supported Supported "Nucleoplasm,Plasma membrane" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 9: T-cells - Adaptive immunity: Regulation" 13 Nucleoplasm "Plasma membrane" "HPA023689: , HPA074813: " "unprognostic (2.22e-1)" "unprognostic (1.23e-1)" "unprognostic (2.69e-1)" "unprognostic (7.87e-2)" "unprognostic (1.13e-2)" "unprognostic (2.77e-1)" "unprognostic (2.01e-1)" "unprognostic (1.95e-2)" "unprognostic (6.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.24e-1)" "unprognostic (9.35e-2)" "unprognostic (2.92e-1)" "potential prognostic unfavorable (3.27e-6)" "unprognostic (5.43e-2)" "unprognostic (1.52e-1)" "unprognostic (3.66e-2)" "unprognostic (1.41e-1)" "unprognostic (1.05e-2)" "unprognostic (4.46e-2)" "unprognostic (1.17e-1)" "unprognostic (2.06e-1)" "unprognostic (4.36e-2)" "unprognostic (2.48e-1)" "unprognostic (1.34e-1)" "unprognostic (1.09e-1)" "unprognostic (3.09e-2)" "unprognostic (9.05e-2)" "unprognostic (9.76e-2)" "unprognostic (1.27e-1)" "unprognostic (1.18e-1)" PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 487.0;Esophageal suprabasal cells: 195.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 487.0;Suprabasal cells: 195.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 100000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 16 "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: , HPA039717: , HPA046200: " "unprognostic (4.92e-1)" "unprognostic (3.55e-2)" "unprognostic (6.83e-2)" "unprognostic (1.47e-1)" "unprognostic (6.14e-2)" "unprognostic (1.02e-1)" "unprognostic (8.02e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (2.82e-2)" "unprognostic (6.95e-2)" "potential prognostic unfavorable (2.70e-5)" "unprognostic (4.22e-3)" "unprognostic (1.35e-1)" "unprognostic (1.06e-1)" "unprognostic (5.57e-2)" "unprognostic (1.31e-2)" "unprognostic (1.43e-1)" "unprognostic (7.84e-2)" "unprognostic (2.18e-1)" "unprognostic (2.93e-1)" "unprognostic (1.33e-1)" "unprognostic (8.97e-2)" "unprognostic (4.13e-2)" "unprognostic (5.99e-2)" "unprognostic (3.04e-1)" "unprognostic (3.65e-1)" "unprognostic (2.24e-3)" QARS1 QARS ENSG00000172053 "Glutaminyl-tRNA synthetase 1" P47897 3 49095932-49105130 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Epilepsy, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 237.9;Early spermatids: 229.1;Esophageal apical cells: 249.6;Late spermatids: 913.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 913.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA036986, HPA036987" Enhanced Enhanced Cytosol No No 110000 "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 25: Non-specific - Ribosome" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 104 Cytosol "HPA036986: , HPA036987: " "unprognostic (4.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.46e-2)" "unprognostic (3.68e-2)" "unprognostic (2.16e-1)" "unprognostic (2.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.50e-2)" "unprognostic (5.76e-3)" "potential prognostic favorable (1.16e-7)" "unprognostic (7.26e-2)" "unprognostic (5.63e-3)" "unprognostic (8.72e-3)" "unprognostic (3.62e-1)" "unprognostic (5.56e-2)" "unprognostic (2.82e-1)" "unprognostic (2.80e-1)" "unprognostic (1.60e-1)" "unprognostic (6.44e-2)" "unprognostic (7.75e-2)" "unprognostic (9.82e-2)" "unprognostic (2.44e-1)" "unprognostic (1.54e-2)" "unprognostic (3.50e-1)" "unprognostic (1.36e-2)" "unprognostic (2.30e-2)" "unprognostic (1.49e-1)" "unprognostic (7.04e-3)" "unprognostic (7.87e-2)" QKI QK3 ENSG00000112531 "QKI, KH domain containing RNA binding" Q96PU8 6 163414000-163578592 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing, mRNA transport, Translation regulation, Transport" "Developmental protein, DNA-binding, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 290.1;tongue: 207.3" "Cell type enhanced" "Detected in many" "Astrocytes: 1812.3;Bergmann glia: 2279.1;Microglia: 1857.9;Myonuclei: 3258.7;Neutrophils: 3082.4;Oligodendrocyte progenitor cells: 1948.4;Oligodendrocytes: 5472.3" "Cell type enhanced" "Detected in many" "Glial cells: 5472.3;Myocytes: 3258.7;Neutrophils: 3082.4" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 4394.7;oligodendrocyte: 7417.4" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 172.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA019123, CAB022602" Enhanced Supported Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 55: Myocytes - Oxidative muscle function" 51 Nucleoplasm "CAB022602: , HPA019123: " "unprognostic (1.34e-3)" "unprognostic (6.87e-2)" "unprognostic (1.29e-1)" "unprognostic (1.09e-2)" "unprognostic (3.19e-2)" "unprognostic (7.13e-2)" "unprognostic (6.54e-2)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" "unprognostic (4.51e-3)" "potential prognostic favorable (1.29e-5)" "unprognostic (1.41e-2)" "unprognostic (1.42e-1)" "unprognostic (1.22e-1)" "unprognostic (8.10e-2)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (2.50e-2)" "unprognostic (3.73e-1)" "unprognostic (1.80e-3)" "unprognostic (8.87e-3)" "unprognostic (5.25e-2)" "unprognostic (1.34e-3)" "unprognostic (1.10e-1)" "unprognostic (5.18e-2)" "unprognostic (3.21e-2)" "unprognostic (2.11e-1)" "unprognostic (1.35e-3)" "unprognostic (1.28e-1)" "unprognostic (9.34e-2)" "unprognostic (2.33e-1)" QPCTL FLJ20084 ENSG00000011478 "Glutaminyl-peptide cyclotransferase like" Q9NXS2 19 45692403-45703989 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Plasma cells: 33.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 4620080.3;B-cells: 3879997.7" "Tissue enhanced" "Detected in many" "lung: 4790925.2" HPA040797 Approved Supported "Golgi apparatus" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 63: Non-specific - Protein processing" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 2 "Golgi apparatus" "HPA040797: " "unprognostic (4.52e-2)" "unprognostic (5.35e-2)" "unprognostic (1.89e-1)" "unprognostic (1.91e-2)" "unprognostic (7.20e-2)" "unprognostic (3.06e-2)" "unprognostic (1.45e-1)" "unprognostic (5.65e-2)" "unprognostic (3.69e-2)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (7.94e-3)" "unprognostic (6.39e-2)" "unprognostic (6.16e-3)" "unprognostic (1.96e-3)" "unprognostic (1.99e-2)" "unprognostic (2.15e-1)" "unprognostic (1.69e-1)" "unprognostic (7.66e-2)" "unprognostic (2.78e-1)" "unprognostic (2.98e-1)" "unprognostic (1.11e-1)" "unprognostic (1.78e-1)" "unprognostic (1.66e-1)" "unprognostic (2.45e-3)" "potential prognostic favorable (6.64e-4)" "unprognostic (2.23e-1)" "unprognostic (1.48e-1)" "unprognostic (2.13e-1)" "unprognostic (2.01e-2)" "unprognostic (1.37e-1)" QPRT QPRTase ENSG00000103485 "Quinolinate phosphoribosyltransferase" Q15274 16 29663279-29698699 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Pyridine nucleotide biosynthesis" "Glycosyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 220.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 487.9;Epididymal efferent duct absorptive cells: 217.2;Epididymal principal cells: 454.0;Extravillous trophoblasts: 413.2;Hepatocytes: 368.0;Hofbauer cells: 234.4;Migrating cytotrophoblasts: 399.7;Syncytiotrophoblasts: 218.7" "Cell type enhanced" "Detected in many" "Hepatocytes: 368.0;Reproductive supporting cells: 454.0;Trophoblast cells: 487.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 4.3;intermediate monocyte: 5.3;myeloid DC: 5.9;non-classical monocyte: 9.1;plasmacytoid DC: 3.1" "Group enriched" "Detected in many" 8 "dendritic cells: 5.9;monocytes: 9.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 172687631.9;Hepatocytes: 102061575.2;Proximal tubules: 152667661.1" "Group enriched" "Detected in many" "kidney: 339219350.2;liver: 209449365.5" "HPA011887, HPA076010" Enhanced Approved Vesicles NA NA 690000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 15 Vesicles "HPA011887: , HPA076010: " "unprognostic (6.57e-3)" "potential prognostic unfavorable (4.34e-5)" "unprognostic (1.90e-2)" "unprognostic (6.66e-2)" "unprognostic (4.27e-2)" "unprognostic (2.15e-2)" "unprognostic (1.34e-3)" "unprognostic (1.23e-3)" "unprognostic (6.90e-2)" "unprognostic (1.05e-1)" "unprognostic (7.07e-2)" "unprognostic (3.83e-2)" "unprognostic (2.65e-2)" "unprognostic (3.17e-2)" "unprognostic (2.66e-3)" "unprognostic (5.51e-2)" "unprognostic (2.47e-1)" "unprognostic (1.48e-2)" "unprognostic (1.84e-2)" "unprognostic (1.12e-1)" "unprognostic (9.62e-2)" "unprognostic (1.54e-1)" "unprognostic (4.94e-3)" "unprognostic (5.04e-2)" "unprognostic (1.20e-2)" "unprognostic (1.61e-1)" "unprognostic (9.57e-2)" "unprognostic (2.41e-3)" "unprognostic (2.71e-1)" "unprognostic (4.74e-2)" "unprognostic (6.37e-2)" R3HCC1 DKFZp564N123 ENSG00000104679 "R3H domain and coiled-coil containing 1" Q9Y3T6 8 23270120-23296279 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 177.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 177.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA023073, HPA023153" Uncertain Approved Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 40: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 1 Cytosol Nucleoplasm "HPA023073: , HPA023153: " "unprognostic (5.20e-3)" "unprognostic (5.08e-2)" "unprognostic (7.64e-2)" "unprognostic (1.03e-2)" "unprognostic (4.57e-3)" "unprognostic (1.39e-3)" "unprognostic (2.53e-1)" "unprognostic (7.09e-2)" "unprognostic (1.68e-2)" "unprognostic (7.45e-3)" "validated prognostic favorable (3.74e-6)" "validated prognostic favorable (5.43e-4)" "unprognostic (1.56e-2)" "unprognostic (1.48e-2)" "unprognostic (8.22e-2)" "unprognostic (1.04e-1)" "unprognostic (8.01e-2)" "unprognostic (2.51e-1)" "unprognostic (5.85e-2)" "unprognostic (3.30e-1)" "unprognostic (9.84e-2)" "potential prognostic favorable (8.04e-4)" "unprognostic (3.28e-1)" "unprognostic (2.22e-2)" "unprognostic (2.96e-2)" "unprognostic (2.20e-1)" "unprognostic (1.40e-1)" "unprognostic (3.16e-2)" "unprognostic (8.20e-2)" "unprognostic (1.75e-1)" "unprognostic (1.49e-3)" RAB11A YL8 ENSG00000103769 "RAB11A, member RAS oncogene family" P62491 15 65726054-65891989 "Enzymes, Predicted intracellular proteins" "Cell cycle, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 2205.9;Esophageal apical cells: 4604.1;Platelets: 1542.8;Syncytiotrophoblasts: 1451.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 4604.1;Barrier epithelial cells: 2205.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" "cerebral cortex: 539111.7;intestine: 588492.2" "CAB013097, HPA051697, HPA060686" Approved Supported "Vesicles,Primary cilium,Centriolar satellite,Basal body,Cytosol,Equatorial segment,Mid piece,Principal piece" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 297 "Vesicles, Centriolar satellite" "Primary cilium, Basal body, Cytosol, Equatorial segment, Mid piece, Principal piece" "CAB013097: , HPA051697: , HPA060686: " "unprognostic (5.90e-2)" "unprognostic (2.37e-3)" "unprognostic (3.32e-1)" "unprognostic (3.02e-1)" "unprognostic (3.60e-1)" "unprognostic (3.28e-1)" "unprognostic (2.00e-1)" "unprognostic (3.37e-2)" "unprognostic (2.99e-2)" "unprognostic (2.68e-2)" "validated prognostic favorable (2.19e-9)" "validated prognostic favorable (1.39e-4)" "unprognostic (1.15e-1)" "unprognostic (1.91e-2)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (1.30e-3)" "unprognostic (5.41e-2)" "unprognostic (5.89e-2)" "unprognostic (2.13e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-1)" "potential prognostic unfavorable (1.56e-5)" "unprognostic (5.12e-2)" "unprognostic (1.45e-1)" "unprognostic (5.02e-2)" "unprognostic (2.98e-1)" "unprognostic (3.46e-1)" "unprognostic (2.52e-1)" "unprognostic (2.08e-1)" "unprognostic (3.64e-2)" "unprognostic (3.25e-2)" RAB11B H-YPT3 ENSG00000185236 "RAB11B, member RAS oncogene family" Q15907 19 8389981-8404434 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 249.2;Syncytiotrophoblasts: 244.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA054396 Approved "Vesicles,Primary cilium,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 52 "Vesicles, Centriolar satellite" "Primary cilium, Basal body, Cytosol" "HPA054396: " "unprognostic (1.96e-3)" "unprognostic (4.74e-2)" "unprognostic (1.36e-1)" "unprognostic (1.40e-1)" "unprognostic (1.54e-1)" "unprognostic (1.46e-1)" "unprognostic (9.38e-2)" "unprognostic (3.22e-1)" "unprognostic (1.75e-3)" "unprognostic (9.66e-2)" "unprognostic (5.56e-3)" "unprognostic (6.91e-2)" "unprognostic (1.50e-2)" "unprognostic (1.68e-1)" "unprognostic (2.26e-2)" "unprognostic (5.96e-2)" "unprognostic (7.30e-2)" "unprognostic (9.01e-2)" "unprognostic (3.09e-2)" "unprognostic (3.41e-2)" "unprognostic (1.26e-1)" "unprognostic (3.83e-3)" "potential prognostic unfavorable (4.82e-4)" "unprognostic (8.84e-2)" "unprognostic (1.96e-1)" "unprognostic (3.34e-2)" "unprognostic (3.76e-2)" "unprognostic (7.29e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (5.57e-2)" RAB11FIP1 "FLJ22524, FLJ22622, Rab11-FIP1, RCP" ENSG00000156675 "RAB11 family interacting protein 1" Q6WKZ4 8 37858618-37899497 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 3603.6;Endometrial glandular cells: 1877.3;Endometrial luminal cells: 1715.8;Esophageal apical cells: 2111.6;Neutrophils: 1173.8;Pancreatic acinar cells: 2154.0;Urothelial cells: 1558.3" "Cell type enhanced" "Detected in many" "Acinar cells: 2154.0;Alveolar cells: 3603.6;Apical squamous epithelial cells: 2111.6" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 153.8;leukocyte: 93.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 7 "choroid plexus: 85.3" "Immune cell enhanced" "Detected in all" "neutrophil: 102.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 102.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 6967619.2" "Tissue enhanced" "Detected in many" "lymphoid tissue: 5181831.4;ovary: 6262787.0" "CAB017037, HPA023904, HPA024010, HPA025960" Enhanced Enhanced Vesicles No No "Cluster 7: Non-specific - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 31 Vesicles "CAB017037: , HPA023904: , HPA024010: , HPA025960: " "unprognostic (3.27e-3)" "unprognostic (6.58e-3)" "unprognostic (1.35e-2)" "unprognostic (2.00e-1)" "unprognostic (2.67e-2)" "unprognostic (3.02e-1)" "unprognostic (5.03e-3)" "unprognostic (1.39e-1)" "unprognostic (1.25e-3)" "unprognostic (3.71e-3)" "potential prognostic favorable (6.94e-6)" "unprognostic (3.09e-1)" "unprognostic (1.47e-1)" "unprognostic (2.98e-1)" "unprognostic (2.03e-1)" "unprognostic (1.03e-1)" "unprognostic (1.73e-2)" "unprognostic (7.39e-2)" "unprognostic (6.84e-2)" "unprognostic (3.43e-2)" "unprognostic (3.21e-3)" "unprognostic (7.82e-3)" "unprognostic (7.99e-2)" "unprognostic (2.57e-2)" "unprognostic (1.38e-2)" "unprognostic (6.96e-3)" "unprognostic (2.50e-1)" "unprognostic (1.91e-1)" "unprognostic (3.02e-1)" "unprognostic (1.07e-1)" "unprognostic (3.59e-1)" RAB11FIP3 "eferin, KIAA0665, Rab11-FIP3" ENSG00000090565 "RAB11 family interacting protein 3" O75154 16 425649-523011 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 151.2" "Cell type enriched" "Detected in many" 7 "Proximal tubule cells: 1639.4" "Cell type enriched" "Detected in many" 7 "Renal nephron cells: 1639.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 5487927.6;Large ducts: 7299536.4;Oocytes: 5908614.1;Proximal tubules: 10423336.6" "Tissue enhanced" "Detected in some" "intestine: 2361397.8" "HPA028088, HPA028631, HPA030086" Enhanced Supported "Vesicles,Cytokinetic bridge,Primary cilium,Centriolar satellite,Basal body" Yes No "Cluster 72: Kidney - Transmembrane transport" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 "Vesicles, Centriolar satellite, Basal body" "Cytokinetic bridge, Primary cilium" "HPA028088: , HPA028631: , HPA030086: " "unprognostic (3.50e-3)" "unprognostic (9.69e-2)" "unprognostic (8.69e-2)" "unprognostic (1.37e-1)" "unprognostic (8.75e-2)" "unprognostic (3.41e-1)" "unprognostic (5.39e-2)" "unprognostic (2.82e-2)" "unprognostic (1.38e-1)" "unprognostic (1.18e-2)" "validated prognostic favorable (6.84e-5)" "validated prognostic favorable (4.76e-4)" "unprognostic (2.20e-2)" "potential prognostic unfavorable (1.69e-5)" "unprognostic (1.06e-1)" "unprognostic (7.99e-2)" "unprognostic (2.19e-1)" "unprognostic (7.29e-2)" "unprognostic (2.61e-2)" "unprognostic (1.17e-1)" "unprognostic (4.44e-2)" "unprognostic (2.95e-3)" "unprognostic (6.96e-2)" "unprognostic (3.34e-1)" "unprognostic (4.18e-2)" "unprognostic (1.28e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.96e-1)" "unprognostic (3.15e-1)" "unprognostic (1.71e-1)" RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 116.2;liver: 51.4;pancreas: 41.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 123.1;Colonocytes: 197.2;Enterocytes: 126.7;Epididymal basal cells: 102.4;Goblet cells: 170.4;Neuroendocrine cells: 124.8;Paneth cells: 247.5" "Cell type enhanced" "Detected in many" "Enterocytes: 197.2;Goblet cells: 170.4;Secretory gland support: 247.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 17.2" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Skeletal myocytes, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Pancreatic islets: 3903629.5" "Tissue enriched" "Detected in single" 175 "cerebral cortex: 17452.8" HPA075624 Uncertain "Vesicles,Plasma membrane,Cell Junctions,Centrosome,Cytosol" No No "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 8 "Plasma membrane, Centrosome" "Vesicles, Cell Junctions, Cytosol" "HPA075624: " "unprognostic (4.08e-2)" "unprognostic (2.15e-2)" "unprognostic (1.73e-1)" "unprognostic (1.03e-3)" "unprognostic (4.62e-2)" "unprognostic (8.65e-3)" "unprognostic (1.66e-1)" "unprognostic (7.08e-2)" "unprognostic (1.13e-1)" "unprognostic (1.34e-2)" "unprognostic (9.52e-2)" "unprognostic (3.85e-2)" "potential prognostic favorable (9.10e-6)" "unprognostic (7.71e-2)" "unprognostic (1.40e-2)" "unprognostic (9.68e-2)" "unprognostic (1.51e-1)" "unprognostic (8.28e-2)" "unprognostic (2.34e-1)" "unprognostic (4.01e-2)" "unprognostic (2.99e-1)" "unprognostic (2.67e-1)" "unprognostic (1.85e-1)" "unprognostic (2.75e-2)" "unprognostic (4.29e-2)" "unprognostic (5.12e-2)" "unprognostic (2.23e-2)" "unprognostic (1.86e-2)" RAB29 "RAB7L, RAB7L1" ENSG00000117280 "RAB29, member RAS oncogene family" O14966 1 205767986-205775482 "Predicted intracellular proteins" "Differentiation, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 68.2" "Cell type enhanced" "Detected in many" "NK-cells: 76.6" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 54.4;leukocyte: 52.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Proximal tubules: 29783907.4" "Tissue enriched" "Detected in many" "liver: 7487358.0" "CAB020822, HPA026303" Approved Approved "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 72: Kidney - Transmembrane transport" "Cluster 39: Astrocytes - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 47 "Nuclear membrane, Vesicles" "Nucleoplasm, Cytosol" "CAB020822: , HPA026303: " "unprognostic (1.33e-2)" "unprognostic (1.35e-1)" "unprognostic (5.87e-3)" "unprognostic (8.77e-2)" "unprognostic (3.26e-2)" "unprognostic (1.82e-1)" "unprognostic (1.24e-1)" "unprognostic (2.19e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (5.87e-6)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (3.27e-2)" "unprognostic (5.19e-2)" "unprognostic (1.93e-1)" "unprognostic (4.31e-1)" "unprognostic (4.91e-2)" "unprognostic (1.56e-3)" "unprognostic (3.16e-1)" "unprognostic (3.32e-1)" "unprognostic (6.96e-2)" "unprognostic (1.90e-1)" "unprognostic (2.94e-3)" "unprognostic (1.30e-1)" "unprognostic (9.08e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (2.99e-2)" RAB34 "NARR, RAB39, RAH" ENSG00000109113 "RAB34, member RAS oncogene family" "P0DI83, Q9BZG1" 17 28714281-28718429 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" Hydrolase "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 128.3;Decidual stromal cells: 220.9;Epididymal basal cells: 127.2;Extravillous trophoblasts: 121.2;Hepatic stellate cells: 142.0;Ovarian stromal cells: 126.9;Peritubular myoid cells: 146.0;Smooth muscle cells: 125.3" "Cell type enhanced" "Detected in many" "Stromal cells: 220.9" "Cell type enhanced" "Detected in many" "astrocyte: 54.7;Bergmann glia: 104.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 51.1;intermediate monocyte: 47.3;myeloid DC: 76.4;non-classical monocyte: 23.5;plasmacytoid DC: 46.7" "Group enriched" "Detected in all" 5 "dendritic cells: 76.4;monocytes: 51.1" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts, Heart muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 5177866.6" "Low tissue specificity" "Detected in many" HPA021366 Approved Approved "Nucleoplasm,Primary cilium,Centrosome,Basal body,Cytosol" NA NA 1700000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 108: Fibroblasts - ECM organization" 2 "Nucleoplasm, Primary cilium" "Centrosome, Basal body, Cytosol" "HPA021366: " "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (1.46e-2)" "unprognostic (2.93e-1)" "unprognostic (3.60e-2)" "unprognostic (2.79e-1)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (2.65e-6)" "unprognostic (3.81e-2)" "unprognostic (7.12e-3)" "unprognostic (5.25e-2)" "unprognostic (2.30e-2)" "unprognostic (5.49e-2)" "unprognostic (5.65e-2)" "unprognostic (1.73e-1)" "unprognostic (7.58e-2)" "unprognostic (2.67e-2)" "unprognostic (6.67e-2)" "unprognostic (1.01e-1)" "unprognostic (9.02e-3)" "unprognostic (2.11e-1)" "unprognostic (8.51e-2)" "unprognostic (5.25e-2)" "unprognostic (2.37e-2)" "unprognostic (9.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.57e-4)" "unprognostic (4.02e-2)" "unprognostic (6.64e-3)" "unprognostic (6.20e-2)" RAB3IL1 GRAB ENSG00000167994 "RAB3A interacting protein like 1" Q8TBN0 11 61897301-61920269 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 126.6;Hofbauer cells: 146.1;Kupffer cells: 51.2;Late spermatids: 191.2;Leydig cells: 57.2;Lymphatic endothelial cells: 28.4;Peritubular myoid cells: 46.1" "Cell type enhanced" "Detected in many" "Leydig cells: 57.2;Mononuclear phagocytes: 146.1;Spermatogenic cell types: 191.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 19.2;fibroblast: 32.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 9298533.6;Proximal tubules: 7001949.9" "Tissue enriched" "Detected in many" "bone marrow: 5568592.1" HPA039723 Uncertain Approved "Centriolar satellite,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 36 "Centriolar satellite, Cytosol" "HPA039723: " "unprognostic (1.08e-1)" "unprognostic (1.53e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (2.79e-4)" "potential prognostic unfavorable (4.46e-4)" "unprognostic (1.56e-1)" "unprognostic (2.67e-1)" "unprognostic (2.40e-1)" "unprognostic (3.43e-3)" "unprognostic (4.41e-2)" "unprognostic (6.65e-2)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "validated prognostic unfavorable (1.68e-6)" "validated prognostic unfavorable (1.73e-4)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (7.27e-2)" "unprognostic (9.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.59e-2)" "unprognostic (3.22e-1)" "unprognostic (2.46e-1)" "unprognostic (3.25e-2)" "unprognostic (1.34e-1)" "unprognostic (2.78e-2)" "unprognostic (6.24e-2)" "unprognostic (4.23e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (1.51e-1)" RAB44 "dJ431A14.3, RASD3, RASL13" ENSG00000255587 "RAB44, member RAS oncogene family" Q7Z6P3 6 36697826-36733184 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 41 "bone marrow: 55.6" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 23.0;Epicardial cells: 61.4;Mast cells: 78.1;Monocyte progenitors: 54.0;Neutrophil progenitors: 88.3;Salivary acinar cells: 16.6;Salivary myoepithelial cells: 33.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 61.4;Mast cells: 78.1;Mononuclear phagocytes: 54.0;Neutrophils: 88.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "basophil: 10.6;eosinophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 10.6" "Cancer enriched" "Detected in single" 135 "Leukemia: 26.6" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Breast - Fibroblasts, Colon - Mast cells, Kidney - T-cells, Minor Salivary Gland - Mast cells, Prostate - Fibroblasts, Spleen - Neutrophils_1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 325039 "Neutrophils: 32503891.8" "Tissue enriched" "Detected in some" "bone marrow: 51863192.5" HPA079390 Approved Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 15: Bone marrow - Innate immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" Vesicles "HPA079390: " RAB5B ENSG00000111540 "RAB5B, member RAS oncogene family" P61020 12 55973913-55996683 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 356.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 356.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Liver - Hepatocytes, Lung - Alveolar cells type 1, Prostate - Smooth muscle cells, Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB010224, HPA068337" Approved Supported Vesicles NA NA 210000 "Cluster 45: Eosinophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 28 Vesicles "CAB010224: , HPA068337: " "unprognostic (1.60e-1)" "unprognostic (2.49e-3)" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (6.56e-2)" "unprognostic (2.35e-1)" "unprognostic (1.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.59e-2)" "unprognostic (3.51e-3)" "potential prognostic favorable (3.86e-6)" "unprognostic (1.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.24e-1)" "unprognostic (6.13e-3)" "unprognostic (2.65e-1)" "unprognostic (1.15e-1)" "unprognostic (9.63e-2)" "unprognostic (1.25e-1)" "unprognostic (2.04e-2)" "potential prognostic unfavorable (7.75e-4)" "unprognostic (5.51e-2)" "unprognostic (3.43e-1)" "unprognostic (1.23e-1)" "unprognostic (6.20e-2)" "unprognostic (2.78e-1)" "unprognostic (3.04e-1)" "unprognostic (3.80e-2)" "unprognostic (2.14e-1)" "unprognostic (1.13e-1)" "unprognostic (1.35e-1)" RAB6A RAB6 ENSG00000175582 "RAB6A, member RAS oncogene family" P20340 11 73675638-73761137 "Predicted intracellular proteins" "ER-Golgi transport, Host-virus interaction, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB009936, HPA059131" Approved Supported "Golgi apparatus,Basal body" NA NA 2300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 33 "Golgi apparatus" "Basal body" "CAB009936: , HPA059131: " "unprognostic (1.88e-1)" "unprognostic (1.05e-1)" "unprognostic (1.80e-1)" "unprognostic (9.30e-3)" "unprognostic (8.93e-2)" "unprognostic (2.56e-2)" "unprognostic (1.83e-1)" "unprognostic (3.62e-2)" "unprognostic (1.40e-1)" "potential prognostic unfavorable (7.97e-4)" "potential prognostic favorable (5.87e-7)" "unprognostic (2.02e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (1.79e-1)" "unprognostic (6.38e-3)" "unprognostic (6.83e-3)" "unprognostic (7.02e-2)" "unprognostic (6.82e-2)" "unprognostic (1.34e-1)" "unprognostic (5.76e-2)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (8.94e-2)" "unprognostic (9.21e-2)" "unprognostic (6.42e-2)" "unprognostic (2.08e-2)" "unprognostic (1.23e-2)" "unprognostic (2.43e-1)" "unprognostic (1.32e-1)" "unprognostic (5.55e-2)" "unprognostic (2.08e-1)" RAB6B ENSG00000154917 "RAB6B, member RAS oncogene family" Q9NRW1 3 133824235-133895882 "Enzymes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 131.0" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 53.2;Brain excitatory neurons: 64.3;Brain inhibitory neurons: 64.4;Choroid plexus epithelial cells: 46.4;Megakaryocytes: 160.7;Oocytes: 73.7;Other brain neurons: 73.8;Platelets: 138.0;Retinal horizontal cells: 46.1;Retinal pigment epithelial cells: 63.9" "Cell type enhanced" "Detected in many" "Megakaryocytes: 160.7;Platelets: 138.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "MAIT T-cell: 7.4" "Lineage enriched" "Detected in single" 47 "T-cells: 7.4" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 28516952.3;Microglia and Neuropil: 26311397.7;Neurons: 12003892.9;Oocytes: 7647276.3" "Tissue enriched" "Detected in many" "cerebral cortex: 53478120.6" "CAB017713, HPA059131" Uncertain Supported "Golgi apparatus,Basal body" NA NA 2600000 "Cluster 1: T-cells - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 109: Neurons - Neuronal signaling" 24 "Golgi apparatus" "Basal body" "CAB017713: , HPA059131: " "unprognostic (4.81e-2)" "unprognostic (2.00e-3)" "unprognostic (3.24e-1)" "unprognostic (4.83e-3)" "unprognostic (9.71e-2)" "unprognostic (2.04e-1)" "unprognostic (1.76e-1)" "unprognostic (8.19e-3)" "unprognostic (1.83e-2)" "unprognostic (2.49e-1)" "unprognostic (4.50e-3)" "unprognostic (6.74e-3)" "unprognostic (7.34e-2)" "unprognostic (2.88e-3)" "potential prognostic unfavorable (8.27e-6)" "unprognostic (1.18e-1)" "unprognostic (3.49e-1)" "unprognostic (1.53e-2)" "unprognostic (2.65e-2)" "unprognostic (2.12e-1)" "unprognostic (1.44e-1)" "unprognostic (2.36e-3)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "unprognostic (1.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.24e-2)" "unprognostic (3.30e-2)" "unprognostic (6.44e-2)" "unprognostic (2.30e-2)" RAB6C WTH3 ENSG00000222014 "RAB6C, member RAS oncogene family" Q9H0N0 2 129979666-129982738 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 2.3;parathyroid gland: 3.4" "Group enriched" "Detected in some" 6 "Epicardial cells: 15.9;Oligodendrocytes: 4.5" "Group enriched" "Detected in some" 6 "Barrier epithelial cells: 15.9;Glial cells: 4.5" "Cell type enhanced" "Detected in some" "oligodendrocyte: 5.9" "Cancer enhanced" "Detected in some" "Breast Invasive Carcinoma (TCGA): 1.8;Prostate Adenocarcinoma (TCGA): 3.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "breast cancer: 1.2;prostate cancer: 4.3" "Breast - Breast glandular cells, Prostate - Prostate glandular cells" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 2450851.2" "Tissue enhanced" "Detected in many" "liver: 959952.1" HPA059131 Uncertain Approved "Golgi apparatus,Basal body" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 60: Prostate cancer - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 8 "Golgi apparatus" "Basal body" "HPA059131: " "unprognostic (7.40e-2)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (7.61e-4)" "unprognostic (6.18e-2)" RAB6D "RAB6CL, WTH3DI" ENSG00000233087 "RAB6D, member RAS oncogene family" Q53S08 2 131360492-131364168 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "parathyroid gland: 6.6;prostate: 1.7" "Cell type enhanced" "Detected in some" "Colonocytes: 1.5;Early primary spermatocytes: 3.5;Enterocytes: 1.2;Gastric progenitor cells: 1.3;Neuroendocrine cells: 1.5;Paneth cells: 3.9;Prostatic glandular cells: 2.3" "Cell type enhanced" "Detected in some" "Enterocytes: 1.5;Enteroendocrine cells: 1.5;Glandular cells: 2.3;Secretory gland support: 3.9;Spermatogenic cell types: 3.5" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 1.1;prostate cancer: 1.6" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA059131 Uncertain Approved "Golgi apparatus,Basal body" NA NA "Cluster 69: Parathyroid gland - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Golgi apparatus" "Basal body" "HPA059131: " "unprognostic (1.90e-1)" "unprognostic (9.85e-2)" "unprognostic (4.60e-2)" "potential prognostic unfavorable (7.79e-4)" RAB8A "MEL, RAB8" ENSG00000167461 "RAB8A, member RAS oncogene family" P61006 19 16111889-16134234 "Enzymes, Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" Hydrolase Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 189.7;Megakaryocytes: 364.7;Platelets: 660.9" "Cell type enhanced" "Detected in all" "Megakaryocytes: 364.7;Platelets: 660.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" HPA041945 Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane,Primary cilium,Centriolar satellite,Basal body,Cytosol" No No 5300000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 77: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 23: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 52 "Nucleoplasm, Nucleoli, Plasma membrane" "Golgi apparatus, Primary cilium, Centriolar satellite, Basal body, Cytosol" "HPA041945: " "unprognostic (6.59e-2)" "unprognostic (1.61e-1)" "unprognostic (2.93e-1)" "unprognostic (2.29e-1)" "unprognostic (1.01e-1)" "unprognostic (1.68e-1)" "unprognostic (4.35e-1)" "unprognostic (2.75e-1)" "unprognostic (2.95e-1)" "unprognostic (2.37e-2)" "unprognostic (2.05e-3)" "unprognostic (1.83e-1)" "unprognostic (1.47e-1)" "unprognostic (1.96e-2)" "unprognostic (1.86e-2)" "unprognostic (6.36e-3)" "unprognostic (8.19e-2)" "unprognostic (2.04e-1)" "unprognostic (2.42e-3)" "unprognostic (3.26e-1)" "unprognostic (5.66e-2)" "unprognostic (4.53e-3)" "unprognostic (1.81e-1)" "unprognostic (1.63e-3)" "unprognostic (3.11e-1)" "unprognostic (8.96e-2)" "unprognostic (1.93e-1)" "unprognostic (2.15e-1)" "unprognostic (1.42e-1)" "unprognostic (1.79e-1)" "unprognostic (1.68e-1)" RABIF "mss4, RASGRF3" ENSG00000183155 "RAB interacting factor" P47224 1 202878282-202889149 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 7 "Late spermatids: 5434.8" "Cell type enriched" "Detected in all" 17 "Spermatogenic cell types: 5434.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA027715, HPA054936" Approved Approved "Microtubules,Cytokinetic bridge" Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 44 "Microtubules, Cytokinetic bridge" "HPA027715: , HPA054936: " "unprognostic (2.86e-2)" "unprognostic (7.02e-3)" "unprognostic (2.07e-1)" "unprognostic (1.18e-1)" "unprognostic (8.97e-2)" "unprognostic (2.95e-1)" "unprognostic (4.85e-1)" "unprognostic (1.88e-2)" "unprognostic (1.56e-2)" "unprognostic (2.66e-3)" "unprognostic (8.82e-3)" "unprognostic (2.00e-1)" "unprognostic (6.64e-3)" "potential prognostic unfavorable (2.60e-4)" "unprognostic (3.73e-2)" "unprognostic (8.40e-2)" "unprognostic (1.71e-1)" "unprognostic (3.75e-2)" "unprognostic (4.34e-2)" "unprognostic (6.23e-2)" "unprognostic (1.14e-2)" "unprognostic (2.24e-2)" "unprognostic (1.94e-1)" "unprognostic (7.43e-2)" "unprognostic (2.76e-2)" "unprognostic (2.17e-3)" "unprognostic (1.79e-3)" "unprognostic (1.11e-1)" "unprognostic (5.44e-2)" "unprognostic (2.14e-1)" "unprognostic (3.26e-1)" RABL2A ENSG00000144134 "RAB, member of RAS oncogene family like 2A" Q9UBK7 2 113627229-113643396 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 20.1" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 124.7;Endometrial ciliated cells: 88.1;Ependymal cells: 222.8;Epididymal efferent duct ciliated cells: 91.5;Epididymal principal cells: 75.0;Fallopian tube ciliated cells: 159.4;Respiratory ciliated cells: 207.9" "Cell type enhanced" "Detected in all" "Ciliated cells: 222.8" "Cell type enhanced" "Detected in all" "ependymal cell: 247.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042642, HPA042700, HPA044007" Approved Approved "Vesicles,Centrosome,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "Centrosome, Basal body" Vesicles "HPA042642: , HPA042700: , HPA044007: " "unprognostic (2.22e-2)" "unprognostic (1.29e-1)" "unprognostic (5.22e-2)" "potential prognostic favorable (3.49e-4)" "unprognostic (1.12e-1)" "unprognostic (2.51e-1)" "unprognostic (6.14e-2)" "unprognostic (3.63e-1)" "unprognostic (3.48e-2)" "potential prognostic favorable (2.34e-6)" "unprognostic (3.76e-3)" "unprognostic (2.18e-1)" "unprognostic (3.03e-2)" "unprognostic (1.71e-2)" "unprognostic (3.63e-1)" "unprognostic (8.06e-2)" "unprognostic (4.65e-2)" "unprognostic (1.66e-1)" "unprognostic (5.38e-2)" "unprognostic (7.09e-2)" "unprognostic (2.68e-3)" "unprognostic (7.60e-2)" "unprognostic (1.06e-1)" "unprognostic (2.75e-1)" "unprognostic (1.27e-1)" "unprognostic (2.50e-1)" "unprognostic (1.80e-1)" "unprognostic (5.01e-2)" "unprognostic (1.79e-1)" RABL2B ENSG00000079974 "RAB, member of RAS oncogene family like 2B" Q9UNT1 22 50767501-50783667 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 84.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 135.5;Ependymal cells: 95.2;Epididymal efferent duct ciliated cells: 124.7;Fallopian tube ciliated cells: 192.2;Respiratory ciliated cells: 248.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 248.2" "Cell type enhanced" "Detected in all" "ependymal cell: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042642, HPA042700, HPA044007" Approved Supported "Vesicles,Centrosome,Basal body" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "Centrosome, Basal body" Vesicles "HPA042642: , HPA042700: , HPA044007: " "unprognostic (1.95e-2)" "unprognostic (1.35e-1)" "unprognostic (5.08e-2)" "unprognostic (3.82e-2)" "unprognostic (3.92e-1)" "unprognostic (3.90e-2)" "unprognostic (1.03e-2)" "unprognostic (1.12e-1)" "unprognostic (2.71e-1)" "unprognostic (7.09e-2)" "unprognostic (9.56e-2)" "unprognostic (2.02e-1)" "unprognostic (8.31e-2)" "potential prognostic unfavorable (6.36e-4)" "unprognostic (6.94e-2)" "unprognostic (2.81e-1)" "unprognostic (1.70e-1)" "unprognostic (1.20e-1)" "unprognostic (5.18e-2)" "unprognostic (1.08e-1)" "unprognostic (1.15e-1)" "unprognostic (3.09e-2)" "unprognostic (1.09e-2)" "unprognostic (7.99e-2)" "unprognostic (6.22e-3)" "unprognostic (1.12e-1)" "unprognostic (3.17e-1)" "unprognostic (2.75e-2)" "unprognostic (2.44e-1)" "unprognostic (3.72e-2)" "unprognostic (8.87e-3)" RABL6 "bA216L13.9, C9orf86, FLJ10101, FLJ13045, Parf, pp8875, RBEL1" ENSG00000196642 "RAB, member RAS oncogene family like 6" Q3YEC7 9 136807943-136841187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA044037 Uncertain Supported "Centriolar satellite,Centrosome,Basal body,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 65: Non-specific - Cell growth & division" 13 "Centrosome, Cytosol" "Centriolar satellite, Basal body" "HPA044037: " "unprognostic (5.69e-2)" "unprognostic (1.03e-2)" "unprognostic (6.18e-2)" "unprognostic (6.19e-2)" "unprognostic (1.51e-1)" "unprognostic (7.85e-2)" "potential prognostic favorable (2.74e-4)" "unprognostic (4.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.97e-3)" "unprognostic (4.12e-2)" "potential prognostic favorable (1.31e-4)" "unprognostic (2.17e-3)" "unprognostic (3.43e-2)" "unprognostic (5.35e-2)" "unprognostic (1.05e-2)" "unprognostic (1.89e-2)" "unprognostic (2.00e-1)" "unprognostic (1.28e-1)" "unprognostic (2.36e-3)" "unprognostic (1.42e-1)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (9.36e-3)" "unprognostic (4.85e-2)" "unprognostic (8.32e-2)" "unprognostic (7.06e-2)" "unprognostic (1.27e-2)" RAC1 "p21-Rac1, Rac-1, TC-25" ENSG00000136238 "Rac family small GTPase 1" P63000 7 6374527-6403967 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 6771.9;Esophageal suprabasal cells: 2039.8;Gastric progenitor cells: 1777.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 6771.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Microglia and Neuropil: 193145.5;Proximal tubules: 413646.2" "Tissue enriched" "Detected in all" "cerebral cortex: 186660349.9" "CAB035994, HPA047820" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA 3400000 "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 84: Apical squamous epithelium - Cornification" 220 "Nucleoplasm, Cytosol" Nucleoli "CAB035994: , HPA047820: " "unprognostic (7.44e-2)" "unprognostic (3.14e-2)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (2.19e-1)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (1.58e-2)" "unprognostic (1.20e-3)" "unprognostic (1.25e-2)" "unprognostic (4.46e-3)" "unprognostic (1.36e-2)" "unprognostic (9.96e-3)" "unprognostic (3.09e-2)" "validated prognostic unfavorable (1.12e-5)" "validated prognostic unfavorable (2.76e-5)" "potential prognostic unfavorable (6.87e-6)" "unprognostic (6.29e-3)" "unprognostic (2.20e-1)" "unprognostic (2.70e-2)" "unprognostic (8.72e-2)" "unprognostic (2.57e-3)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (7.07e-2)" "unprognostic (5.64e-2)" "unprognostic (3.21e-1)" "unprognostic (9.53e-2)" "unprognostic (1.20e-1)" "unprognostic (1.87e-1)" "unprognostic (6.45e-3)" "unprognostic (4.42e-1)" "unprognostic (1.79e-1)" RACGAP1 "CYK4, MgcRacGAP" ENSG00000161800 "Rac GTPase activating protein 1" Q9H0H5 12 49976923-50033136 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein, GTPase activation" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 36.7;lymphoid tissue: 40.0;testis: 42.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 89.8;Erythrocyte progenitors: 76.0;Extravillous trophoblasts: 63.2;Gastric progenitor cells: 51.3;Late primary spermatocytes: 53.4;Monocyte progenitors: 105.7;Neutrophil progenitors: 66.2;Renal collecting duct intercalated cells: 49.4" "Cell type enhanced" "Detected in many" "Erythrocytes: 76.0;Mononuclear phagocytes: 105.7;Spermatogenic cell types: 89.8" "Cell type enhanced" "Detected in all" "Bergmann glia: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4705 "Granulosa cells: 470527.0" "Tissue enriched" "Detected in single" 26974 "bone marrow: 2697393.5" "CAB025859, HPA039427, HPA043912" Enhanced Enhanced Nucleoplasm Yes Yes "Cluster 32: Basophils - Transcription" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 56 Nucleoplasm "CAB025859: , HPA039427: , HPA043912: " "unprognostic (3.32e-2)" "unprognostic (1.00e-3)" "unprognostic (7.38e-3)" "unprognostic (1.01e-1)" "unprognostic (1.78e-2)" "unprognostic (1.41e-1)" "unprognostic (1.87e-1)" "unprognostic (9.45e-2)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (1.30e-5)" "unprognostic (7.48e-3)" "potential prognostic unfavorable (5.95e-4)" "potential prognostic unfavorable (4.71e-4)" "validated prognostic unfavorable (2.74e-6)" "validated prognostic unfavorable (3.27e-7)" "validated prognostic unfavorable (2.07e-6)" "validated prognostic unfavorable (3.33e-4)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (4.16e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (7.67e-3)" "unprognostic (6.39e-2)" "unprognostic (1.15e-2)" "unprognostic (1.14e-1)" "unprognostic (3.33e-2)" "unprognostic (2.94e-2)" "unprognostic (1.46e-1)" "unprognostic (9.57e-2)" "unprognostic (2.65e-1)" RAD1 "HRAD1, REC1" ENSG00000113456 "RAD1 checkpoint DNA exonuclease" O60671 5 34905260-34918989 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 96.9;Migrating cytotrophoblasts: 92.1;Oocytes: 119.7;Syncytiotrophoblasts: 103.2" "Cell type enhanced" "Detected in all" "Oocytes: 119.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Uterine Corpus Endometrial Carcinoma (TCGA): 52.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Distal tubules: 90232.4;Oocytes: 97253.9;Proximal tubules: 78391.4" "Tissue enriched" "Detected in single" 5412 "lymphoid tissue: 541241.0" HPA006692 Approved Approved Nucleoplasm,Vesicles NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 28 "Nucleoplasm, Vesicles" "HPA006692: " "unprognostic (9.24e-3)" "unprognostic (5.32e-3)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (3.27e-1)" "unprognostic (3.23e-2)" "unprognostic (3.45e-1)" "unprognostic (2.67e-1)" "unprognostic (1.10e-1)" "unprognostic (3.14e-2)" "unprognostic (1.42e-3)" "potential prognostic favorable (5.86e-4)" "unprognostic (3.55e-2)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.81e-3)" "unprognostic (3.18e-2)" "unprognostic (6.16e-2)" "unprognostic (3.67e-1)" "unprognostic (6.45e-2)" "unprognostic (2.01e-3)" "unprognostic (4.28e-1)" "unprognostic (4.24e-2)" "unprognostic (1.28e-2)" "unprognostic (4.04e-3)" "unprognostic (8.51e-3)" "unprognostic (3.18e-1)" "unprognostic (2.26e-2)" "unprognostic (4.33e-2)" "unprognostic (1.98e-1)" "unprognostic (1.02e-1)" "unprognostic (1.18e-1)" RAD18 RNF73 ENSG00000070950 "RAD18 E3 ubiquitin protein ligase" Q9NS91 3 8775402-8963773 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 1484939.3;Oocytes: 4012459.7" "Not detected" "Not detected" "HPA006716, HPA006724, HPA008752, CAB080160, CAB080162" Supported Approved Supported "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA Yes "Cluster 5: Non-specific - Cell proliferation" "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 35: Neurons - Synaptic function & neurogenesis" 67 "Nucleoplasm, Nuclear bodies" "Nuclear speckles" "CAB080160: , CAB080162: , HPA006716: , HPA006724: , HPA008752: " "unprognostic (3.07e-1)" "unprognostic (1.34e-2)" "unprognostic (2.51e-1)" "unprognostic (7.57e-3)" "unprognostic (1.23e-1)" "unprognostic (8.36e-2)" "unprognostic (3.24e-2)" "unprognostic (2.85e-1)" "unprognostic (9.33e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (3.39e-2)" "unprognostic (6.52e-2)" "unprognostic (3.77e-1)" "potential prognostic unfavorable (1.21e-4)" "unprognostic (1.38e-3)" "unprognostic (4.79e-3)" "unprognostic (2.00e-2)" "unprognostic (8.02e-2)" "unprognostic (1.33e-2)" "unprognostic (1.34e-1)" "unprognostic (6.13e-3)" "unprognostic (3.84e-2)" "unprognostic (8.46e-3)" "potential prognostic unfavorable (7.99e-4)" "unprognostic (1.51e-3)" "unprognostic (1.35e-3)" "unprognostic (1.78e-1)" "unprognostic (5.72e-2)" "unprognostic (3.34e-1)" "unprognostic (1.87e-2)" "unprognostic (9.18e-2)" RAD23B "HHR23B, HR23B, P58" ENSG00000119318 "RAD23 homolog B, nucleotide excision repair protein" P54727 9 107283137-107332192 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2069.5;Neutrophils: 668.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 2069.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA029718, HPA029720, CAB033868" Enhanced Supported Nucleoplasm,Cytosol No No 4800000 "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 72 Nucleoplasm Cytosol "CAB033868: , HPA029718: , HPA029720: " "unprognostic (1.22e-1)" "unprognostic (1.41e-3)" "unprognostic (1.87e-1)" "unprognostic (7.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.01e-2)" "unprognostic (1.82e-2)" "unprognostic (1.41e-1)" "unprognostic (1.98e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (1.32e-6)" "unprognostic (1.08e-2)" "unprognostic (1.97e-2)" "unprognostic (2.74e-1)" "unprognostic (4.69e-3)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (1.64e-3)" "unprognostic (5.89e-2)" "unprognostic (1.06e-1)" "unprognostic (2.67e-2)" "unprognostic (8.11e-3)" "unprognostic (7.83e-3)" "unprognostic (4.10e-1)" "unprognostic (3.96e-2)" "unprognostic (2.13e-1)" "unprognostic (2.87e-1)" "unprognostic (1.60e-1)" "unprognostic (1.57e-1)" "unprognostic (2.88e-1)" "unprognostic (4.53e-2)" "unprognostic (1.44e-2)" RAD51AP1 PIR51 ENSG00000111247 "RAD51 associated protein 1" Q96B01 12 4538798-4560047 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Meiosis" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.9;lymphoid tissue: 13.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 41.4;Early primary spermatocytes: 56.0;Early spermatids: 58.5;Enteric transient amplifying cells: 41.9;Erythrocyte progenitors: 78.8;Extravillous trophoblasts: 41.3;Hofbauer cells: 65.0;Late spermatids: 121.3;Megakaryocyte progenitors: 50.8;Migrating cytotrophoblasts: 36.4;Monocyte progenitors: 65.3;Neutrophil progenitors: 36.5;Oocytes: 69.1" "Cell type enhanced" "Detected in many" "Erythrocytes: 78.8;Mononuclear phagocytes: 65.3;Oocytes: 69.1;Spermatogenic cell types: 121.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 7.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 20868 "Granulosa cells: 2086827.5" "Not detected" "Not detected" HPA051499 Approved Nucleoplasm Yes Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 10 Nucleoplasm "HPA051499: " "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (8.25e-2)" "unprognostic (1.82e-1)" "unprognostic (2.00e-1)" "unprognostic (9.71e-2)" "unprognostic (1.50e-3)" "unprognostic (2.35e-2)" "unprognostic (4.84e-2)" "unprognostic (6.41e-3)" "potential prognostic unfavorable (4.98e-5)" "potential prognostic unfavorable (3.31e-8)" "validated prognostic unfavorable (3.36e-4)" "validated prognostic unfavorable (1.94e-4)" "unprognostic (1.15e-3)" "unprognostic (1.95e-3)" "unprognostic (1.75e-3)" "unprognostic (1.69e-1)" "unprognostic (1.46e-2)" "unprognostic (3.37e-1)" "validated prognostic unfavorable (9.46e-5)" "validated prognostic unfavorable (1.26e-5)" "unprognostic (7.85e-2)" "unprognostic (1.46e-2)" "unprognostic (9.93e-3)" "unprognostic (1.39e-2)" "unprognostic (5.18e-2)" "unprognostic (1.83e-1)" "unprognostic (7.54e-2)" "unprognostic (2.89e-1)" RAD51C "FANCO, RAD51L2" ENSG00000108384 "RAD51 paralog C" O43502 17 58692573-58735611 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 164.8;Extravillous trophoblasts: 128.9;Late primary spermatocytes: 149.5;Oocytes: 216.4" "Cell type enhanced" "Detected in all" "Oocytes: 216.4;Spermatogenic cell types: 164.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 107489.7;Neutrophils: 42306.6" "Not detected" "Not detected" HPA045198 Supported "Nucleoplasm,Vesicles,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 33 "Nucleoplasm, Mitochondria, Cytosol" "Vesicles, Cell Junctions" "HPA045198: " "unprognostic (3.72e-1)" "unprognostic (3.02e-3)" "unprognostic (3.01e-2)" "unprognostic (4.17e-3)" "unprognostic (1.34e-1)" "unprognostic (9.50e-2)" "unprognostic (4.12e-1)" "unprognostic (3.66e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (8.40e-4)" "unprognostic (6.49e-3)" "unprognostic (2.66e-1)" "unprognostic (9.19e-2)" "validated prognostic unfavorable (2.22e-5)" "validated prognostic unfavorable (1.02e-7)" "unprognostic (3.54e-2)" "unprognostic (1.79e-1)" "unprognostic (9.82e-3)" "unprognostic (3.04e-3)" "unprognostic (7.89e-3)" "unprognostic (1.20e-1)" "unprognostic (7.23e-3)" "unprognostic (9.75e-2)" "unprognostic (7.81e-2)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (6.09e-3)" "unprognostic (6.65e-2)" "unprognostic (6.47e-2)" "unprognostic (7.20e-2)" "unprognostic (8.48e-2)" RAD9A RAD9 ENSG00000172613 "RAD9 checkpoint clamp component A" Q99638 11 67317871-67398410 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "DNA damage" "Exonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 274.3;Choroid plexus epithelial cells: 277.5;Epicardial cells: 459.4" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 459.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 7625641.2;T-cells: 5750215.1" "Tissue enhanced" "Detected in many" "fallopian tube: 10798487.8" "HPA006725, HPA048155, CAB079979" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 49: Non-specific - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 43 Nucleoplasm "Nuclear bodies" "CAB079979: , HPA006725: , HPA048155: " "unprognostic (2.83e-2)" "unprognostic (7.86e-2)" "unprognostic (1.77e-1)" "unprognostic (1.98e-1)" "unprognostic (9.49e-3)" "unprognostic (9.54e-2)" "unprognostic (2.85e-1)" "unprognostic (9.15e-3)" "potential prognostic favorable (7.89e-4)" "unprognostic (6.47e-2)" "unprognostic (3.20e-2)" "unprognostic (5.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.05e-3)" "unprognostic (2.36e-2)" "unprognostic (4.53e-2)" "unprognostic (7.31e-3)" "unprognostic (1.73e-1)" "unprognostic (2.41e-1)" "unprognostic (1.29e-1)" "potential prognostic favorable (4.41e-4)" "unprognostic (1.42e-1)" "unprognostic (1.94e-3)" "unprognostic (1.06e-2)" "unprognostic (4.12e-3)" "potential prognostic favorable (6.77e-4)" "unprognostic (1.38e-1)" "unprognostic (7.48e-2)" "unprognostic (3.26e-1)" "unprognostic (2.94e-1)" "unprognostic (1.32e-1)" RAG1 "MGC43321, RNF74" ENSG00000166349 "Recombination activating 1" P15918 11 36510372-36593156 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "DNA recombination, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Endonuclease, Hydrolase, Multifunctional enzyme, Nuclease, Transferase" "Disease variant, SCID" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 90 "lymphoid tissue: 367.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 7.6;Loop of henle epithelial cells: 8.2;Salivary ionocytes: 38.0;Sertoli cells: 11.2" "Cell type enhanced" "Detected in many" "Ionocytes: 38.0" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 6.8;endothelial cell: 6.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Leukemia: 31.4;lymphoma: 11.6" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 55173 "Alveolar cell types: 5517324.3" "Not detected" "Not detected" "HPA043939, HPA073731" Approved Nucleoplasm,Nucleoli NA NA "Cluster 80: Thymus - Adaptive immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 Nucleoplasm Nucleoli "HPA043939: , HPA073731: " "unprognostic (3.22e-1)" "potential prognostic unfavorable (5.27e-5)" "unprognostic (2.05e-2)" "potential prognostic favorable (2.16e-5)" "potential prognostic favorable (6.84e-4)" "unprognostic (1.94e-2)" "unprognostic (1.02e-1)" "unprognostic (1.09e-1)" RALY "HNRPCL2, P542" ENSG00000125970 "RALY heterogeneous nuclear ribonucleoprotein" Q9UKM9 20 33993646-34108308 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA040971, HPA043614" Enhanced Enhanced Nucleoplasm,Vesicles NA NA 7900 "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 81 Nucleoplasm Vesicles "HPA040971: , HPA043614: " "unprognostic (5.34e-2)" "unprognostic (3.96e-2)" "unprognostic (4.62e-1)" "unprognostic (9.09e-2)" "unprognostic (1.92e-1)" "unprognostic (1.61e-1)" "unprognostic (3.62e-2)" "unprognostic (1.08e-1)" "unprognostic (3.28e-2)" "unprognostic (4.52e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (1.47e-1)" "unprognostic (3.93e-1)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (3.87e-6)" "unprognostic (2.44e-1)" "unprognostic (9.52e-3)" "unprognostic (1.05e-2)" "unprognostic (1.66e-1)" "unprognostic (4.30e-2)" "unprognostic (5.54e-2)" "unprognostic (3.15e-2)" "unprognostic (7.34e-2)" "unprognostic (1.31e-2)" "unprognostic (1.35e-2)" "unprognostic (1.18e-2)" "unprognostic (3.76e-1)" "unprognostic (6.27e-2)" "unprognostic (2.26e-1)" "unprognostic (1.23e-1)" "unprognostic (1.99e-1)" RAMAC "C15orf18, FAM103A1, HsT19360, MGC2560, RAM, RAMMET" ENSG00000169612 "RNA guanine-7 methyltransferase activating subunit" Q9BTL3 15 82986210-82991057 "Predicted intracellular proteins" "mRNA capping, mRNA processing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 38.9;Late primary spermatocytes: 49.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 38.9;Spermatogenic cell types: 49.3" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Group enriched" "Detected in some" "Neurons: 160432.3;Oocytes: 102369.8" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2732104.2" "HPA041923, HPA041948" Supported Supported Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" 50 Nucleoplasm "HPA041923: , HPA041948: " "unprognostic (9.65e-2)" "unprognostic (1.58e-1)" "unprognostic (2.66e-3)" "unprognostic (7.75e-3)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (5.42e-3)" "unprognostic (4.75e-2)" "unprognostic (3.22e-1)" "unprognostic (3.99e-3)" "unprognostic (5.79e-2)" "unprognostic (4.65e-2)" "unprognostic (4.36e-1)" "unprognostic (2.19e-3)" "unprognostic (2.54e-3)" "unprognostic (1.07e-3)" "unprognostic (1.29e-1)" "unprognostic (1.10e-2)" "unprognostic (1.61e-1)" "unprognostic (8.37e-2)" "unprognostic (1.14e-2)" "unprognostic (1.60e-2)" "unprognostic (2.72e-1)" "unprognostic (2.22e-1)" "unprognostic (2.12e-1)" "unprognostic (2.60e-1)" "unprognostic (1.45e-1)" "unprognostic (4.96e-2)" "unprognostic (1.80e-1)" RAMACL "C6orf119, dJ427A4.2, FAM103A2P, RAMMETL" ENSG00000235272 "RNA guanine-7 methyltransferase activating subunit like (pseudogene)" 6 166583009-166586678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA041923, HPA041948" Uncertain Approved Nucleoplasm No NA "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" Nucleoplasm "HPA041923: , HPA041948: " "unprognostic (3.99e-1)" "unprognostic (3.50e-1)" RAMP1 ENSG00000132329 "Receptor activity modifying protein 1" O60894 2 237858893-237912106 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 533.5;endometrium 1: 693.9" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 2218.0;Endometrial stromal cells: 455.2;Epididymal efferent duct absorptive cells: 407.1;Epididymal principal cells: 422.9;Hepatic stellate cells: 355.0;Paneth cells: 328.7;Smooth muscle cells: 816.6;Thymic myoid cells: 552.0" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 816.6;Stromal cells: 2218.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 172.9" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 334.5;Prostate Adenocarcinoma (TCGA): 361.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 18 "NK-cell: 70.4" "Lineage enriched" "Detected in many" 18 "NK-cells: 70.4" "Cancer enhanced" "Detected in many" "prostate cancer: 147.8" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA057814 Approved "Nucleoplasm,Nuclear membrane" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 39: Astrocytes - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Nucleoplasm, Nuclear membrane" "HPA057814: " "unprognostic (1.79e-2)" "unprognostic (3.83e-2)" "unprognostic (2.22e-1)" "unprognostic (2.20e-1)" "unprognostic (2.96e-2)" "unprognostic (1.89e-2)" "unprognostic (3.84e-1)" "unprognostic (2.35e-2)" "unprognostic (9.64e-2)" "unprognostic (5.50e-2)" "unprognostic (1.34e-1)" "unprognostic (1.29e-1)" "unprognostic (5.77e-2)" "unprognostic (1.04e-3)" "unprognostic (4.77e-2)" "unprognostic (1.11e-1)" "unprognostic (5.21e-3)" "unprognostic (1.22e-1)" "unprognostic (1.18e-1)" "unprognostic (9.47e-3)" "unprognostic (2.80e-1)" "unprognostic (1.33e-1)" "unprognostic (3.42e-1)" "unprognostic (7.22e-2)" "unprognostic (4.28e-3)" "unprognostic (1.68e-1)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (3.38e-5)" "unprognostic (2.78e-1)" "unprognostic (3.64e-2)" "unprognostic (5.08e-2)" RAN "ARA24, Gsp1, TC4" ENSG00000132341 "RAN, member RAS oncogene family" P62826 12 130872037-130877678 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Host-virus interaction, Mitosis, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 1497.6;Esophageal suprabasal cells: 1062.0;Extravillous trophoblasts: 1365.9;Gastric progenitor cells: 906.1;Late primary spermatocytes: 1000.7;Migrating cytotrophoblasts: 1241.5" "Cell type enhanced" "Detected in all" "Basal cells: 1497.6;Trophoblast cells: 1365.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA063353 Supported Nucleoplasm No No 5400000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 272 Nucleoplasm "HPA063353: " "potential prognostic unfavorable (1.12e-4)" "unprognostic (1.23e-1)" "unprognostic (2.60e-1)" "unprognostic (7.04e-3)" "unprognostic (1.19e-2)" "unprognostic (1.99e-1)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (5.48e-4)" "unprognostic (4.52e-2)" "potential prognostic favorable (2.83e-4)" "potential prognostic unfavorable (6.89e-4)" "unprognostic (1.14e-3)" "validated prognostic unfavorable (1.96e-10)" "validated prognostic unfavorable (3.56e-8)" "potential prognostic unfavorable (1.93e-5)" "unprognostic (1.30e-3)" "unprognostic (9.10e-2)" "unprognostic (3.31e-1)" "unprognostic (1.46e-2)" "unprognostic (4.29e-1)" "unprognostic (5.74e-3)" "unprognostic (5.60e-2)" "unprognostic (5.50e-3)" "unprognostic (1.17e-1)" "unprognostic (2.77e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (6.57e-2)" "unprognostic (3.09e-1)" "unprognostic (2.88e-1)" RANBP17 ENSG00000204764 "RAN binding protein 17" Q9H2T7 5 170861870-171300015 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 342.8;Alveolar cells type 1: 545.4;Choroid plexus epithelial cells: 468.8" "Cell type enhanced" "Detected in many" "Alveolar cells: 545.4;Ciliated cells: 468.8" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 611.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 40826.2;Oocytes: 136286.0" "Not detected" "Not detected" "HPA029568, HPA029569" Uncertain Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Cytosol" Yes No "Cluster 8: Pancreas - Proteolysis" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 "Nucleoplasm, Nuclear bodies" "Nuclear membrane, Cytosol" "HPA029568: , HPA029569: " "unprognostic (4.09e-2)" "unprognostic (4.41e-2)" "potential prognostic favorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (6.78e-2)" "unprognostic (2.54e-1)" "unprognostic (1.59e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-1)" RANBP2 "ADANE, ANE1, NUP358" ENSG00000153201 "RAN binding protein 2" P49792 2 108719482-108785810 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport, Ubl conjugation pathway" "RNA-binding, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Innate lymphoid cells: 547.3;Mast cells: 554.3;pDCs: 537.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 96722170.0" "Tissue enhanced" "Detected in many" "lymphoid tissue: 48638372.4" "HPA018437, HPA018445, HPA023960, CAB034063, HPA049497, HPA051675, HPA067564" Supported Supported "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA 41000 "Cluster 1: T-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 103: Non-specific - Basic cellular processes" 93 "Nuclear membrane" "Nucleoplasm, Vesicles, Cytosol" "CAB034063: , HPA018437: , HPA018445: , HPA023960: , HPA049497: , HPA051675: , HPA067564: " "unprognostic (3.51e-1)" "unprognostic (1.30e-1)" "unprognostic (2.15e-1)" "unprognostic (6.22e-2)" "unprognostic (3.80e-1)" "unprognostic (4.66e-2)" "unprognostic (5.09e-2)" "unprognostic (4.63e-2)" "unprognostic (1.59e-1)" "unprognostic (1.09e-2)" "potential prognostic favorable (5.17e-8)" "unprognostic (3.15e-3)" "unprognostic (3.45e-2)" "unprognostic (7.04e-2)" "unprognostic (1.42e-1)" "unprognostic (1.17e-1)" "unprognostic (1.14e-1)" "unprognostic (2.03e-2)" "unprognostic (9.41e-2)" "unprognostic (1.87e-1)" "unprognostic (1.50e-3)" "unprognostic (9.39e-2)" "unprognostic (2.47e-2)" "unprognostic (5.24e-2)" "unprognostic (2.49e-2)" "unprognostic (2.21e-2)" "unprognostic (2.48e-1)" "unprognostic (8.23e-2)" "unprognostic (9.86e-2)" "unprognostic (3.30e-2)" "unprognostic (1.89e-1)" RANBP9 RanBPM ENSG00000010017 "RAN binding protein 9" Q96S59 6 13621498-13711835 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1328.5;Neutrophil progenitors: 470.7;Neutrophils: 488.0" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1328.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 4144772.3" "Tissue enriched" "Detected in many" "cerebral cortex: 13624630.7" "HPA023427, CAB033767, HPA050007, HPA076784" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 128 Nucleoplasm "Nuclear bodies, Cytosol" "CAB033767: , HPA023427: , HPA050007: , HPA076784: " "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.40e-1)" "unprognostic (2.79e-1)" "unprognostic (2.60e-1)" "unprognostic (2.82e-2)" "unprognostic (7.72e-2)" "unprognostic (1.18e-2)" "potential prognostic favorable (6.75e-4)" "potential prognostic unfavorable (7.31e-4)" "potential prognostic favorable (1.21e-5)" "unprognostic (6.53e-3)" "unprognostic (1.85e-1)" "unprognostic (2.31e-1)" "unprognostic (1.72e-1)" "unprognostic (8.45e-2)" "unprognostic (1.90e-2)" "unprognostic (5.00e-1)" "unprognostic (1.30e-2)" "unprognostic (1.01e-2)" "unprognostic (4.78e-2)" "unprognostic (2.03e-1)" "unprognostic (1.67e-1)" "unprognostic (2.13e-2)" "unprognostic (5.51e-2)" "unprognostic (8.03e-3)" "unprognostic (4.32e-2)" "unprognostic (2.13e-2)" "unprognostic (3.75e-1)" "unprognostic (2.26e-1)" "unprognostic (2.98e-1)" RANGAP1 "Fug1, KIAA1835, SD" ENSG00000100401 "Ran GTPase activating protein 1" P46060 22 41244779-41286187 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 156.9" "Cell type enriched" "Detected in many" 9 "Late spermatids: 3236.3" "Cell type enriched" "Detected in many" 36 "Spermatogenic cell types: 3236.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004293, HPA050110, HPA062034" Supported Supported "Nuclear membrane,Vesicles,Cytosol,Flagellar centriole" Yes Yes 150000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 67: Testis - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 64 "Nuclear membrane" "Vesicles, Cytosol, Flagellar centriole" "CAB004293: , HPA050110: , HPA062034: " "unprognostic (6.05e-2)" "unprognostic (8.20e-2)" "unprognostic (2.22e-1)" "unprognostic (1.01e-1)" "unprognostic (4.45e-2)" "unprognostic (3.98e-1)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (2.28e-1)" "unprognostic (4.14e-2)" "unprognostic (3.67e-3)" "unprognostic (7.38e-2)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (1.13e-2)" "unprognostic (1.27e-3)" "unprognostic (6.24e-2)" "unprognostic (9.12e-2)" "unprognostic (1.70e-3)" "unprognostic (2.03e-1)" "unprognostic (5.09e-2)" "unprognostic (8.43e-2)" "unprognostic (1.33e-1)" "unprognostic (4.28e-2)" "unprognostic (8.35e-2)" "unprognostic (5.45e-2)" "unprognostic (2.27e-1)" "unprognostic (2.34e-3)" "unprognostic (7.12e-2)" "unprognostic (7.72e-3)" "unprognostic (4.12e-1)" RANGRF "HSPC165, HSPC236, MOG1, RANGNRF" ENSG00000108961 "RAN guanine nucleotide release factor" Q9HD47 17 8288654-8290092 "Predicted intracellular proteins" "Protein transport, Transport" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Late spermatids: 2171.7" "Cell type enriched" "Detected in all" 15 "Spermatogenic cell types: 2171.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 90385.6;Fallopian tube cells: 144340.8;Granulosa cells: 142767.9;Oocytes: 37114.9;T-cells: 51230.1" "Tissue enhanced" "Detected in many" "skeletal muscle: 5893705.1" "HPA057280, HPA057888" Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 21: Testis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 35: RS4;11 - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 12 Nucleoplasm Cytosol "HPA057280: , HPA057888: " "unprognostic (2.11e-1)" "unprognostic (4.68e-2)" "unprognostic (6.15e-3)" "unprognostic (8.47e-3)" "unprognostic (1.27e-1)" "unprognostic (2.03e-1)" "unprognostic (4.81e-2)" "unprognostic (7.38e-2)" "unprognostic (1.98e-2)" "unprognostic (2.23e-2)" "unprognostic (2.80e-2)" "unprognostic (6.63e-3)" "unprognostic (3.92e-2)" "unprognostic (2.68e-3)" "unprognostic (1.17e-3)" "unprognostic (8.18e-2)" "unprognostic (6.48e-2)" "unprognostic (1.32e-1)" "unprognostic (4.17e-1)" "unprognostic (1.46e-1)" "unprognostic (5.95e-2)" "potential prognostic favorable (1.70e-4)" "unprognostic (3.96e-1)" "unprognostic (3.73e-1)" "unprognostic (1.49e-1)" "unprognostic (1.83e-1)" "unprognostic (1.65e-1)" "unprognostic (2.07e-1)" "unprognostic (3.26e-1)" "unprognostic (3.55e-1)" "unprognostic (7.59e-3)" RAP1GAP2 "GARNL4, KIAA1039" ENSG00000132359 "RAP1 GTPase activating protein 2" Q684P5 17 2755705-3037741 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 26.2;pancreas: 36.5" "Cell type enhanced" "Detected in many" "Neuroendocrine cells: 430.6;Neutrophil progenitors: 412.5;Neutrophils: 915.5;Pancreatic islet cells: 385.9;Retinal ganglion cells: 633.5;Thymocytes: 446.3" "Cell type enhanced" "Detected in all" "Neuronal cells: 633.5;Neutrophils: 915.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Stomach - Parietal cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 5952313.8;Microglia and Neuropil: 9581028.1;Neurons: 6393513.9" "Group enriched" "Detected in many" "cerebral cortex: 21681337.1;lung: 15107435.5" "HPA022148, HPA022896" Approved Approved "Nuclear membrane,Cytosol,Perinuclear theca,Flagellar centriole,Principal piece" NA NA 20000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 8: Pancreas - Proteolysis" "Cluster 53: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 1 "Nuclear membrane, Cytosol" "Perinuclear theca, Flagellar centriole, Principal piece" "HPA022148: , HPA022896: " "unprognostic (6.09e-2)" "unprognostic (1.07e-3)" "unprognostic (1.03e-1)" "unprognostic (2.05e-2)" "unprognostic (1.27e-1)" "unprognostic (9.06e-2)" "unprognostic (2.21e-1)" "unprognostic (1.43e-1)" "unprognostic (4.88e-2)" "unprognostic (1.98e-1)" "unprognostic (1.09e-3)" "unprognostic (1.09e-2)" "unprognostic (3.22e-2)" "unprognostic (3.31e-2)" "unprognostic (5.14e-2)" "unprognostic (3.36e-1)" "unprognostic (4.95e-3)" "unprognostic (6.40e-3)" "unprognostic (6.11e-2)" "unprognostic (5.03e-1)" "unprognostic (1.45e-1)" "unprognostic (2.40e-2)" "unprognostic (1.76e-1)" "unprognostic (2.38e-3)" "unprognostic (5.40e-2)" "unprognostic (7.12e-2)" "unprognostic (8.22e-2)" "unprognostic (2.83e-2)" "unprognostic (7.46e-2)" "unprognostic (1.52e-1)" RAPGEFL1 Link-GEFII ENSG00000108352 "Rap guanine nucleotide exchange factor like 1" Q9UHV5 17 40177010-40195656 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 194.7;skin 1: 231.9;vagina: 109.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 112.4;Colonocytes: 113.1;Enterocytes: 114.4;Esophageal apical cells: 249.4;Esophageal basal cells: 121.0;Esophageal suprabasal cells: 254.4;Ocular epithelial cells: 148.7;Papillary tip epithelial cells: 104.0;Prostatic hillock cells: 238.5;Respiratory basal cells: 121.7;Respiratory secretory cells: 94.8;Suprabasal keratinocytes: 197.5;Urothelial cells: 104.2" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 249.4;Barrier epithelial cells: 238.5;Suprabasal cells: 254.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 53.8" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Urothelial cells, Skin - Keratinocyte (other), Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Keratinocytes: 1264811.6;Neurons: 889023.7" "Tissue enriched" "Detected in single" 836 "cerebral cortex: 83581.1" HPA022895 Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes No "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" "Nucleoplasm, Microtubules" "Cytokinetic bridge" "HPA022895: " "unprognostic (3.72e-3)" "unprognostic (1.40e-2)" "unprognostic (1.80e-1)" "unprognostic (9.91e-3)" "unprognostic (6.23e-2)" "unprognostic (1.09e-2)" "unprognostic (1.42e-1)" "unprognostic (6.69e-3)" "unprognostic (4.10e-2)" "unprognostic (7.76e-2)" "potential prognostic unfavorable (5.88e-9)" "unprognostic (6.12e-3)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (7.71e-2)" "unprognostic (6.87e-2)" "unprognostic (1.92e-1)" "unprognostic (6.24e-2)" "unprognostic (7.15e-2)" "unprognostic (5.58e-2)" "unprognostic (4.04e-1)" "unprognostic (1.89e-2)" "unprognostic (6.67e-3)" "unprognostic (2.17e-1)" "potential prognostic unfavorable (4.42e-5)" "unprognostic (1.51e-2)" "unprognostic (1.89e-1)" "unprognostic (1.20e-1)" "unprognostic (1.75e-2)" "unprognostic (1.44e-1)" "unprognostic (6.83e-2)" "unprognostic (2.29e-1)" RARA "NR1B1, RAR, RAR-alpha, RARalpha" ENSG00000131759 "Retinoic acid receptor alpha" P10276 17 40309180-40357643 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 170.1;Late spermatids: 303.7;monocytes: 112.6;Neutrophils: 281.0" "Cell type enhanced" "Detected in all" "Neutrophils: 281.0;Spermatogenic cell types: 303.7" "Cell type enhanced" "Detected in many" "leukocyte: 42.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 52.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1593 "Fallopian tube cells: 159336.0" "Not detected" "Not detected" "HPA058282, HPA071548" Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 104 Nucleoplasm "Nucleoli, Actin filaments, Cytosol" "HPA058282: , HPA071548: " "unprognostic (1.53e-2)" "unprognostic (1.93e-1)" "unprognostic (8.07e-2)" "unprognostic (2.99e-3)" "unprognostic (2.55e-1)" "unprognostic (8.95e-2)" "unprognostic (9.26e-3)" "unprognostic (2.45e-1)" "unprognostic (1.13e-2)" "unprognostic (9.12e-2)" "potential prognostic favorable (9.68e-4)" "unprognostic (1.09e-2)" "unprognostic (2.88e-1)" "unprognostic (2.62e-1)" "unprognostic (1.43e-1)" "unprognostic (1.27e-1)" "unprognostic (4.02e-2)" "unprognostic (6.10e-2)" "unprognostic (1.22e-1)" "unprognostic (1.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.28e-1)" "unprognostic (1.27e-1)" "unprognostic (2.21e-1)" "unprognostic (7.92e-2)" "unprognostic (4.01e-2)" "unprognostic (1.87e-1)" "unprognostic (6.51e-3)" "unprognostic (3.65e-2)" "unprognostic (6.68e-2)" "unprognostic (3.15e-3)" RASA4 "CAPRI, GAPL, KIAA0538" ENSG00000105808 "RAS p21 protein activator 4" O43374 7 102579646-102616756 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 223.0;tongue: 76.1" "Cell type enhanced" "Detected in some" "Astrocytes: 12.9;Bergmann glia: 17.9;Brain inhibitory neurons: 2.6;Ependymal cells: 5.6;Microglia: 12.1;Oligodendrocyte progenitor cells: 4.7;Other brain neurons: 4.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 5.6;Glial cells: 17.9;Neuronal cells: 4.0" "Cell type enhanced" "Detected in many" "astrocyte: 18.6;central nervous system macrophage: 14.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" "Macrophages: 12625733.1;Oocytes: 13177390.8;Pancreatic islets: 31183005.1;Skeletal myofibers: 27909033.9" "Group enriched" "Detected in some" "cerebral cortex: 19154491.5;fallopian tube: 11464571.1;lymphoid tissue: 21205688.0" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 28: Astrocytes - Homeostasis & neuron support" Vesicles "Cell Junctions" "HPA043010: " "unprognostic (1.82e-3)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" "unprognostic (1.07e-2)" "unprognostic (6.97e-3)" "unprognostic (1.53e-1)" "unprognostic (7.56e-2)" "unprognostic (9.54e-3)" "unprognostic (2.29e-1)" "unprognostic (2.43e-1)" "potential prognostic favorable (2.18e-4)" "unprognostic (3.74e-1)" "unprognostic (1.48e-2)" "unprognostic (3.54e-2)" "unprognostic (2.65e-1)" "unprognostic (8.14e-2)" "unprognostic (3.88e-1)" "unprognostic (1.56e-2)" "unprognostic (4.33e-2)" "unprognostic (6.67e-2)" "unprognostic (2.77e-2)" "unprognostic (2.55e-3)" "unprognostic (6.63e-2)" "unprognostic (1.59e-1)" "unprognostic (5.10e-3)" "unprognostic (3.14e-1)" "unprognostic (1.73e-3)" "potential prognostic unfavorable (7.74e-4)" "unprognostic (6.15e-2)" "unprognostic (1.57e-1)" "unprognostic (3.70e-2)" RASA4B ENSG00000170667 "RAS p21 protein activator 4B" C9J798 7 102479976-102517777 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skeletal muscle: 93.2" "Cell type enriched" "Detected in many" 7 "Myonuclei: 160.7" "Cell type enriched" "Detected in many" 7 "Myocytes: 160.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.2;intermediate monocyte: 1.6;myeloid DC: 3.2;plasmacytoid DC: 1.9" "Group enriched" "Detected in many" 6 "dendritic cells: 3.2;monocytes: 2.2" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" Vesicles "Cell Junctions" "HPA043010: " "unprognostic (7.45e-2)" "unprognostic (8.31e-2)" "unprognostic (3.40e-3)" "unprognostic (4.75e-2)" "unprognostic (3.89e-2)" "unprognostic (6.54e-2)" "unprognostic (5.78e-2)" "unprognostic (9.31e-2)" "unprognostic (4.84e-2)" "unprognostic (3.23e-1)" "unprognostic (7.23e-2)" "unprognostic (1.50e-1)" "unprognostic (9.05e-2)" "unprognostic (1.21e-2)" "unprognostic (8.87e-2)" "unprognostic (3.38e-2)" "unprognostic (1.29e-2)" "unprognostic (1.60e-2)" "potential prognostic favorable (3.09e-4)" "unprognostic (1.72e-1)" "unprognostic (2.99e-1)" "unprognostic (3.03e-2)" "unprognostic (1.26e-1)" "unprognostic (9.37e-2)" "potential prognostic unfavorable (8.15e-4)" "unprognostic (5.92e-2)" "unprognostic (1.40e-2)" "unprognostic (5.15e-2)" RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 22.2;intestine: 19.0;lung: 10.6;lymphoid tissue: 39.2" "Cell type enhanced" "Detected in some" "B-cells: 45.9;Hematopoietic stem cells: 25.2;Innate lymphoid cells: 54.8;Mast cells: 29.2;Microglia: 60.6;Neutrophil progenitors: 64.6;Neutrophils: 42.1;NK-cells: 98.1;Plasma cells: 23.9;T-cells: 92.5;Thymocytes: 33.9" "Cell type enhanced" "Detected in many" "Glial cells: 60.6;Innate lymphoid cells: 54.8;Neutrophils: 64.6;NK-cells: 98.1;T-cells: 92.5" "Group enriched" "Detected in some" 115 "central nervous system macrophage: 70.8;leukocyte: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 17 "Leukemia: 25.6;lymphoma: 20.9;Myeloma: 29.9" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "B-cells: 32750575.1;Neutrophils: 27964741.5;T-cells: 55677052.0" "Tissue enriched" "Detected in many" "lymphoid tissue: 82411293.0" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 15 "Nucleoplasm, Plasma membrane" "HPA043417: " "unprognostic (9.30e-3)" "unprognostic (2.01e-2)" "unprognostic (1.01e-3)" "unprognostic (2.68e-3)" "unprognostic (8.80e-2)" "unprognostic (6.17e-2)" "unprognostic (1.79e-1)" "unprognostic (6.95e-2)" "potential prognostic favorable (7.56e-4)" "unprognostic (5.72e-2)" "unprognostic (6.64e-2)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (7.63e-2)" "unprognostic (4.31e-3)" "unprognostic (1.01e-2)" "unprognostic (5.68e-2)" "unprognostic (1.47e-1)" "unprognostic (2.19e-1)" "unprognostic (3.91e-1)" "unprognostic (5.46e-2)" "unprognostic (2.59e-2)" "unprognostic (1.55e-1)" "unprognostic (2.23e-1)" "unprognostic (1.27e-1)" "unprognostic (4.08e-2)" "unprognostic (8.99e-3)" "unprognostic (3.66e-1)" "unprognostic (2.48e-2)" "unprognostic (2.71e-2)" "unprognostic (1.26e-1)" RASGRP2 CALDAG-GEFI ENSG00000068831 "RAS guanyl releasing protein 2" Q7LDG7 11 64726911-64745456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 139.0;lymphoid tissue: 137.9" "Group enriched" "Detected in many" 6 "Megakaryocytes: 636.7;Platelets: 1342.3" "Group enriched" "Detected in many" 6 "Megakaryocytes: 636.7;Platelets: 1342.3" "Cell type enhanced" "Detected in all" "pericyte: 98.7;vascular associated smooth muscle cell: 79.8" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 25.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Leukemia: 109.2;lymphoma: 43.8" "Adrenal gland - Fibroblasts, Prostate - Smooth muscle cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 9395829.8;Macrophages: 5669205.0;Neutrophils: 16082595.1;T-cells: 8705057.0" "Tissue enhanced" "Detected in many" "lymphoid tissue: 22109350.7" "HPA015635, HPA015667" Approved Supported "Plasma membrane" NA NA 700000 "Cluster 29: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 33: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 47: Platelets - Hemostasis" "Plasma membrane" "HPA015635: , HPA015667: " "unprognostic (5.99e-2)" "unprognostic (9.43e-2)" "unprognostic (2.31e-2)" "unprognostic (1.57e-2)" "unprognostic (1.05e-1)" "unprognostic (2.00e-1)" "unprognostic (9.30e-3)" "unprognostic (6.79e-3)" "unprognostic (1.91e-3)" "unprognostic (1.65e-2)" "unprognostic (2.65e-2)" "unprognostic (5.02e-2)" "unprognostic (1.17e-1)" "unprognostic (2.80e-2)" "potential prognostic favorable (7.55e-5)" "potential prognostic favorable (2.57e-4)" "unprognostic (3.81e-2)" "unprognostic (9.56e-3)" "unprognostic (3.06e-1)" "unprognostic (2.88e-1)" "unprognostic (8.57e-2)" "unprognostic (7.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.41e-2)" "unprognostic (2.36e-1)" "unprognostic (5.58e-2)" "unprognostic (3.45e-1)" "unprognostic (1.49e-2)" "unprognostic (6.72e-2)" "unprognostic (1.61e-2)" "unprognostic (2.12e-1)" RASL11A ENSG00000122035 "RAS like family 11 member A" Q6T310 13 27270830-27275192 "Enzymes, Predicted intracellular proteins" "Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 108.1;Enterocytes: 100.7;Epicardial cells: 50.0;Goblet cells: 43.1;Pericytes: 95.9;Smooth muscle cells: 62.0;Vascular smooth muscle cells: 113.5" "Cell type enhanced" "Detected in many" "Enterocytes: 108.1;Mural cells: 113.5" "Group enriched" "Detected in many" 4 "hippocampal CA4: 30.5;pericyte: 47.9;vascular associated smooth muscle cell: 33.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rhabdoid: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Collecting ducts: 135493.7;Distal tubules: 157058.2;Smooth muscle cells: 77917.4" "Not detected" "Not detected" "HPA004859, HPA053296" Supported Approved "Nuclear bodies" Yes No "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 65: Non-specific - Cell growth & division" 12 "Nuclear bodies" "HPA004859: , HPA053296: " "unprognostic (1.51e-2)" "unprognostic (1.99e-1)" "unprognostic (8.68e-3)" "unprognostic (1.31e-1)" "unprognostic (2.75e-3)" "unprognostic (1.79e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-2)" "unprognostic (4.38e-2)" "unprognostic (5.65e-2)" "unprognostic (1.35e-1)" "unprognostic (5.81e-3)" "unprognostic (3.77e-3)" "unprognostic (6.49e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.24e-4)" "unprognostic (9.91e-2)" "unprognostic (1.22e-1)" "unprognostic (2.93e-1)" "unprognostic (4.15e-1)" "unprognostic (8.81e-2)" "unprognostic (3.02e-2)" "unprognostic (9.66e-3)" "unprognostic (9.47e-2)" "unprognostic (1.39e-1)" "unprognostic (2.29e-2)" "unprognostic (5.49e-2)" "unprognostic (1.58e-1)" "unprognostic (1.16e-1)" "unprognostic (1.34e-1)" RASSF2 "CENP-34, KIAA0168" ENSG00000101265 "Ras association domain family member 2" P50749 20 4780023-4823608 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 286.3;retina: 150.9" "Cell type enhanced" "Detected in many" "cDC: 153.9;Monocyte progenitors: 197.2;monocytes: 230.2;Neutrophil progenitors: 424.5;Neutrophils: 1212.7;Oligodendrocytes: 121.6;pDCs: 122.2;Peritubular myoid cells: 180.0;Rod photoreceptor cells: 323.5" "Cell type enhanced" "Detected in many" "Neuronal cells: 323.5;Neutrophils: 1212.7" "Group enriched" "Detected in many" 7 "Bergmann glia: 58.8;central nervous system macrophage: 96.6;committed oligodendrocyte precursor: 51.1;fibroblast: 69.9;leukocyte: 53.5;oligodendrocyte: 182.8;oligodendrocyte precursor cell: 73.6" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 79.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 37.1;lymphoma: 46.2" "Adrenal gland - Fibroblasts, Pituitary gland - Fibroblasts, Skin - Fibroblasts_1, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 10285844.4;Macrophages: 7647232.0;Neutrophils: 8589835.5;T-cells: 10307267.4" "Group enriched" "Detected in many" "bone marrow: 2742996.5;lymphoid tissue: 5636591.8" HPA051200 Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 39 Nucleoplasm "Golgi apparatus, Plasma membrane, Cytosol" "HPA051200: " "unprognostic (3.97e-2)" "unprognostic (9.17e-2)" "unprognostic (3.88e-2)" "unprognostic (6.80e-3)" "unprognostic (1.24e-1)" "unprognostic (4.39e-1)" "unprognostic (2.95e-1)" "unprognostic (3.83e-1)" "unprognostic (3.47e-3)" "unprognostic (2.40e-1)" "potential prognostic favorable (6.63e-4)" "unprognostic (1.58e-2)" "unprognostic (1.34e-1)" "unprognostic (2.02e-1)" "unprognostic (4.37e-3)" "unprognostic (6.83e-3)" "unprognostic (1.26e-2)" "unprognostic (6.66e-2)" "unprognostic (2.15e-1)" "unprognostic (2.49e-3)" "unprognostic (6.04e-2)" "unprognostic (1.01e-1)" "unprognostic (1.17e-1)" "unprognostic (2.97e-1)" "unprognostic (3.28e-1)" "unprognostic (1.44e-1)" "unprognostic (2.40e-2)" "unprognostic (1.95e-2)" "unprognostic (3.23e-1)" "unprognostic (1.53e-1)" "unprognostic (5.42e-2)" RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 76.5" "Cell type enhanced" "Detected in many" "Adipocytes: 182.4;Astrocytes: 173.2;Bergmann glia: 303.0;cDC: 155.8;Epididymal efferent duct absorptive cells: 164.4;Hofbauer cells: 285.5;Müller glia: 265.5;Myosatellite cells: 200.0;Proximal tubule cells: 407.1;Schwann cells: 147.6" "Cell type enhanced" "Detected in many" "Glial cells: 303.0;Mononuclear phagocytes: 285.5;Renal nephron cells: 407.1" "Cell type enhanced" "Detected in all" "astrocyte: 223.0;Bergmann glia: 323.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 85.0;intermediate monocyte: 64.0;myeloid DC: 84.3;non-classical monocyte: 38.2" "Group enriched" "Detected in many" 10 "dendritic cells: 84.3;monocytes: 85.0" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Macrophages, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Large ducts: 109578.9;Proximal tubules: 63630.7" "Tissue enriched" "Detected in single" 35 "lymphoid tissue: 3466.8" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 88: Proximal tubular cells - Transmembrane transport" 11 "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: , HPA077069: " "unprognostic (2.22e-1)" "unprognostic (9.38e-3)" "unprognostic (5.62e-2)" "unprognostic (2.13e-3)" "unprognostic (6.99e-2)" "unprognostic (3.36e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (2.25e-5)" "unprognostic (1.04e-1)" "unprognostic (2.15e-2)" "unprognostic (1.45e-3)" "unprognostic (1.73e-1)" "unprognostic (5.00e-2)" "unprognostic (9.67e-3)" "unprognostic (1.32e-2)" "unprognostic (2.32e-1)" "unprognostic (2.12e-3)" "unprognostic (1.27e-1)" "unprognostic (7.43e-2)" "unprognostic (1.72e-1)" "unprognostic (7.25e-2)" "unprognostic (3.11e-2)" "unprognostic (1.51e-2)" "unprognostic (3.76e-1)" "unprognostic (8.88e-2)" "unprognostic (5.09e-3)" "unprognostic (1.82e-2)" "unprognostic (4.76e-2)" "unprognostic (1.79e-1)" "unprognostic (3.76e-2)" "unprognostic (3.28e-1)" RB1 "OSRC, PPP1R130, RB" ENSG00000139687 "RB transcriptional corepressor 1" P06400 13 48303744-48599436 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Melanocytes: 563.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 2706764.2" "Tissue enhanced" "Detected in some" "fallopian tube: 2013915.4;intestine: 2053340.8" "CAB000095, CAB016687, HPA050082" Supported Supported "Nucleoplasm,Primary cilium transition zone" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 218 Nucleoplasm "Primary cilium transition zone" "CAB000095: , CAB016687: , HPA050082: " "unprognostic (1.68e-1)" "unprognostic (3.92e-2)" "unprognostic (5.31e-2)" "unprognostic (1.54e-2)" "unprognostic (2.25e-2)" "unprognostic (8.89e-2)" "unprognostic (6.26e-2)" "unprognostic (3.24e-1)" "unprognostic (1.04e-1)" "unprognostic (1.12e-1)" "potential prognostic favorable (2.72e-8)" "unprognostic (4.20e-2)" "unprognostic (1.61e-1)" "unprognostic (1.82e-2)" "unprognostic (3.78e-2)" "unprognostic (3.83e-2)" "unprognostic (3.89e-3)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (9.67e-4)" "unprognostic (1.29e-3)" "unprognostic (2.31e-2)" "unprognostic (1.66e-1)" "unprognostic (1.50e-1)" "unprognostic (1.01e-1)" "unprognostic (9.63e-2)" "unprognostic (4.24e-2)" "unprognostic (3.03e-2)" "unprognostic (4.80e-2)" "unprognostic (1.21e-1)" "unprognostic (2.50e-1)" RBBP4 "lin-53, NURF55, RbAp48" ENSG00000162521 "RB binding protein 4, chromatin remodeling factor" Q09028 1 32651142-32686211 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, DNA replication, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB006264, HPA060710, HPA060724" Supported Enhanced Nucleoplasm NA NA 390000 "Cluster 13: Non-specific - Mitochondria" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 262 Nucleoplasm "CAB006264: , HPA060710: , HPA060724: " "unprognostic (1.66e-2)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (9.68e-4)" "unprognostic (1.95e-1)" "unprognostic (9.73e-3)" "unprognostic (1.47e-1)" "unprognostic (2.01e-2)" "unprognostic (1.87e-2)" "unprognostic (7.26e-2)" "unprognostic (2.50e-3)" "potential prognostic favorable (2.07e-6)" "unprognostic (1.31e-2)" "unprognostic (1.85e-1)" "unprognostic (1.51e-3)" "unprognostic (1.15e-3)" "unprognostic (3.88e-1)" "unprognostic (3.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.90e-1)" "unprognostic (7.35e-2)" "unprognostic (7.62e-2)" "unprognostic (6.96e-3)" "unprognostic (1.51e-1)" "unprognostic (8.27e-2)" "unprognostic (1.95e-2)" "unprognostic (2.47e-2)" "unprognostic (2.28e-1)" "unprognostic (9.94e-2)" "unprognostic (2.70e-1)" "unprognostic (7.74e-2)" "unprognostic (1.34e-1)" RBBP5 "RBQ3, SWD1" ENSG00000117222 "RB binding protein 5, histone lysine methyltransferase complex subunit" Q15291 1 205086142-205122015 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA049042, HPA058085" Uncertain Supported Nucleoplasm,Nucleoli No No "Cluster 32: Basophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 20: Non-specific - Transcription regulation" 86 "Nucleoplasm, Nucleoli" "HPA049042: , HPA058085: " "unprognostic (5.90e-2)" "unprognostic (1.89e-3)" "unprognostic (1.69e-1)" "unprognostic (4.87e-2)" "unprognostic (2.90e-2)" "unprognostic (2.60e-1)" "unprognostic (3.42e-1)" "unprognostic (5.69e-2)" "unprognostic (4.55e-1)" "unprognostic (7.77e-3)" "potential prognostic favorable (6.45e-5)" "unprognostic (6.90e-2)" "unprognostic (5.29e-3)" "unprognostic (1.05e-2)" "unprognostic (2.38e-1)" "unprognostic (4.83e-2)" "unprognostic (5.54e-2)" "unprognostic (1.38e-1)" "unprognostic (4.82e-3)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (5.87e-4)" "unprognostic (1.29e-1)" "unprognostic (1.70e-2)" "unprognostic (2.54e-2)" "unprognostic (2.96e-3)" "unprognostic (1.26e-1)" "unprognostic (7.34e-2)" "unprognostic (2.83e-2)" "unprognostic (1.59e-1)" "unprognostic (3.80e-2)" "unprognostic (4.12e-2)" RBBP7 RbAp46 ENSG00000102054 "RB binding protein 7, chromatin remodeling factor" Q16576 X 16839283-16870362 "Predicted intracellular proteins" "DNA replication, Transcription, Transcription regulation" "Chaperone, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 529.8;Epididymal principal cells: 457.5;Migrating cytotrophoblasts: 398.4;Oocytes: 327.0;Syncytiotrophoblasts: 621.2" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 457.5;Trophoblast cells: 621.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 13462784.9" "Tissue enhanced" "Detected in all" "bone marrow: 34434821.9" "CAB037084, HPA060710, HPA060724" Supported Enhanced Nucleoplasm NA NA 190000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 206 Nucleoplasm "CAB037084: , HPA060710: , HPA060724: " "unprognostic (2.31e-1)" "unprognostic (6.28e-2)" "unprognostic (2.50e-1)" "unprognostic (1.14e-1)" "unprognostic (5.12e-3)" "unprognostic (8.06e-2)" "unprognostic (1.24e-2)" "unprognostic (2.05e-3)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (2.75e-5)" "potential prognostic favorable (9.91e-6)" "unprognostic (1.60e-2)" "unprognostic (1.69e-1)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.66e-3)" "unprognostic (3.65e-3)" "unprognostic (7.13e-2)" "unprognostic (5.63e-3)" "unprognostic (4.65e-2)" "unprognostic (1.08e-1)" "unprognostic (1.05e-1)" "unprognostic (3.63e-2)" "unprognostic (2.10e-1)" "unprognostic (4.15e-2)" "unprognostic (7.00e-3)" "unprognostic (9.69e-3)" "unprognostic (4.36e-2)" "unprognostic (2.96e-1)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (5.09e-2)" RBFOX1 "A2BP1, FOX-1, HRNBP1" ENSG00000078328 "RNA binding fox-1 homolog 1" Q9NWB1 16 5239802-7713340 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 65.9;skeletal muscle: 80.8;tongue: 41.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 6364.6;Brain inhibitory neurons: 6575.7;Epicardial cells: 1423.6;Lactotrophs: 1931.7;Myonuclei: 2310.7;Neutrophil progenitors: 1675.6;Oligodendrocyte progenitor cells: 1432.4;Other brain neurons: 2689.9;Podocytes: 3330.3;Retinal amacrine cells: 2565.0;Retinal ganglion cells: 3692.8;Thymic myoid cells: 1877.6" "Cell type enhanced" "Detected in many" "Myocytes: 2310.7;Neuronal cells: 6575.7;Pituitary endocrine cells: 1931.7;Renal nephron cells: 3330.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 3.8;lung cancer: 3.6;Neuroblastoma: 4.4;Sarcoma: 3.9" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 2209484.7" "Tissue enriched" "Detected in single" 3547 "cerebral cortex: 354680.2" "HPA040809, HPA066746, HPA075862" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Golgi apparatus,Cytosol" No No "Cluster 25: Non-specific - Basic cellular processes" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 33 Nucleoplasm "Nucleoli fibrillar center, Golgi apparatus, Cytosol" "HPA040809: , HPA066746: , HPA075862: " "unprognostic (2.42e-2)" "unprognostic (4.43e-2)" "unprognostic (3.24e-2)" "unprognostic (2.61e-1)" "unprognostic (2.07e-1)" "unprognostic (7.34e-2)" "unprognostic (2.00e-1)" RBIS C8orf59 ENSG00000176731 "Ribosomal biogenesis factor" Q8N0T1 8 85214048-85220421 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 103536.5" "Not detected" "Not detected" "HPA044805, HPA071903" Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 21: Non-specific - Metabolism" "Cluster 40: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 1 "Nucleoplasm, Nucleoli" Cytosol "HPA044805: , HPA071903: " "unprognostic (5.65e-2)" "unprognostic (1.12e-3)" "potential prognostic favorable (7.55e-4)" "unprognostic (1.35e-1)" "unprognostic (1.68e-1)" "unprognostic (1.72e-2)" "unprognostic (5.75e-2)" "unprognostic (2.63e-2)" "unprognostic (8.40e-2)" "potential prognostic unfavorable (3.80e-5)" "unprognostic (2.18e-2)" "unprognostic (1.29e-2)" "unprognostic (7.50e-3)" "unprognostic (1.72e-2)" "unprognostic (5.35e-2)" "unprognostic (9.51e-2)" "unprognostic (1.18e-1)" "unprognostic (1.94e-1)" "unprognostic (3.33e-3)" "unprognostic (5.86e-3)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (2.40e-1)" "unprognostic (1.86e-1)" "unprognostic (2.55e-2)" "unprognostic (3.31e-2)" "unprognostic (3.78e-2)" "unprognostic (7.01e-2)" "unprognostic (2.59e-1)" "unprognostic (9.36e-2)" RBKS "DKFZp686G13268, RBSK" ENSG00000171174 Ribokinase Q9H477 2 27781379-27890681 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 43.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 171.4;Mast cells: 212.1;monocytes: 227.4;Neutrophils: 211.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 10608595.5;Hepatocytes: 16591740.8" "Group enriched" "Detected in all" "intestine: 17628659.8;kidney: 29486730.2;liver: 42744457.1" "HPA019725, HPA028285" Enhanced Approved Nucleoplasm,Cytosol No No 13000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 76: Non-specific - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 103: Non-specific - Basic cellular processes" 5 Cytosol Nucleoplasm "HPA019725: , HPA028285: " "unprognostic (2.14e-2)" "unprognostic (1.02e-1)" "unprognostic (1.59e-1)" "unprognostic (3.49e-2)" "unprognostic (1.31e-2)" "unprognostic (1.32e-3)" "unprognostic (1.68e-3)" "unprognostic (4.63e-3)" "unprognostic (1.76e-1)" "unprognostic (1.59e-1)" "unprognostic (1.62e-3)" "unprognostic (2.64e-2)" "unprognostic (2.33e-2)" "unprognostic (9.17e-3)" "unprognostic (1.17e-1)" "unprognostic (9.59e-2)" "unprognostic (8.17e-3)" "unprognostic (2.19e-1)" "unprognostic (3.54e-3)" "unprognostic (3.88e-1)" "unprognostic (2.01e-3)" "unprognostic (3.03e-1)" "unprognostic (5.87e-1)" "unprognostic (3.19e-1)" "unprognostic (5.77e-2)" "unprognostic (2.64e-1)" "unprognostic (1.37e-2)" "unprognostic (5.60e-2)" "unprognostic (7.21e-2)" "unprognostic (8.36e-2)" "unprognostic (8.28e-2)" RBL2 "p130, Rb2" ENSG00000103479 "RB transcriptional corepressor like 2" Q08999 16 53433977-53491648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 539.5" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 539.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 16097868.9" "Tissue enriched" "Detected in some" "intestine: 3115248.5" "CAB016547, HPA019703" Supported Supported "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Cytosol" Yes No "Cluster 27: T-cells - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 53 "Nucleoplasm, Nucleoli rim, Mitotic chromosome" Cytosol "CAB016547: , HPA019703: " "unprognostic (1.74e-1)" "unprognostic (9.35e-2)" "unprognostic (2.19e-1)" "unprognostic (1.15e-2)" "unprognostic (1.09e-1)" "unprognostic (2.85e-1)" "unprognostic (1.11e-1)" "unprognostic (2.94e-2)" "unprognostic (8.85e-2)" "unprognostic (1.77e-1)" "potential prognostic favorable (1.08e-7)" "unprognostic (1.67e-2)" "unprognostic (3.84e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (2.49e-4)" "unprognostic (8.89e-2)" "unprognostic (1.59e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (2.89e-2)" "unprognostic (4.81e-2)" "unprognostic (8.60e-2)" "unprognostic (3.07e-2)" "unprognostic (1.46e-1)" "potential prognostic favorable (7.48e-4)" "unprognostic (1.14e-1)" "unprognostic (3.22e-1)" "unprognostic (1.01e-1)" "unprognostic (9.21e-2)" "unprognostic (9.33e-3)" "unprognostic (3.77e-1)" RBM14 "COAA, DKFZp779J0927, SIP, SYTIP1" ENSG00000239306 "RNA binding motif protein 14" Q96PK6 11 66616626-66629934 "Essential proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Astrocytes: 36.4;Bergmann glia: 45.2;Brain excitatory neurons: 33.5;Brain inhibitory neurons: 35.4;Choroid plexus epithelial cells: 95.6;Ependymal cells: 48.5;Microglia: 59.9;Oligodendrocyte progenitor cells: 34.1;Oligodendrocytes: 34.8;Other brain neurons: 27.6" "Group enriched" "Detected in some" 10 "Ciliated cells: 95.6;Glial cells: 59.9;Neuronal cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 149418477.1" "Tissue enhanced" "Detected in all" "lymphoid tissue: 105104725.0" HPA006628 Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA 5400 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 22: Non-specific - Basic cellular functions" 187 Nucleoplasm "Nuclear speckles, Cytosol" "HPA006628: " "unprognostic (1.15e-1)" "unprognostic (9.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.23e-1)" "unprognostic (5.88e-2)" "unprognostic (5.61e-2)" "unprognostic (3.35e-1)" "unprognostic (7.43e-2)" "unprognostic (4.91e-2)" "unprognostic (9.02e-2)" "unprognostic (1.37e-3)" "unprognostic (1.24e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (3.39e-2)" "unprognostic (6.75e-2)" "unprognostic (3.92e-3)" "unprognostic (9.45e-2)" "unprognostic (6.41e-2)" "unprognostic (9.93e-2)" "unprognostic (5.28e-2)" "potential prognostic favorable (6.34e-4)" "unprognostic (6.81e-3)" "unprognostic (5.76e-2)" "unprognostic (6.91e-3)" "unprognostic (1.35e-1)" "unprognostic (5.55e-2)" "unprognostic (1.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.58e-1)" "unprognostic (2.97e-2)" RBM18 MGC2734 ENSG00000119446 "RNA binding motif protein 18" Q96H35 9 122237622-122264840 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 107.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1091 "Granulosa cells: 109139.8" "Not detected" "Not detected" "HPA057281, HPA077955" Uncertain Enhanced "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 27: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 2 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA057281: , HPA077955: " "unprognostic (2.65e-2)" "unprognostic (1.01e-2)" "unprognostic (1.47e-2)" "unprognostic (1.95e-1)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (7.94e-5)" "unprognostic (1.36e-1)" "unprognostic (8.53e-2)" "unprognostic (1.08e-2)" "unprognostic (1.92e-1)" "potential prognostic favorable (1.26e-7)" "unprognostic (1.40e-3)" "unprognostic (1.61e-1)" "unprognostic (4.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.67e-2)" "unprognostic (3.82e-1)" "unprognostic (2.34e-3)" "unprognostic (8.84e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (6.37e-5)" "unprognostic (1.64e-1)" "unprognostic (8.48e-2)" "unprognostic (1.18e-1)" "unprognostic (2.70e-1)" "unprognostic (1.08e-1)" "unprognostic (1.38e-2)" "unprognostic (1.55e-1)" "unprognostic (1.75e-1)" "unprognostic (9.75e-2)" "unprognostic (1.13e-1)" RBM3 IS1-RNPL ENSG00000102317 "RNA binding motif protein 3" P98179 X 48574449-48581162 "Predicted intracellular proteins" "Stress response" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 873.2;Megakaryocytes: 840.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 14532640.5;Keratinocytes: 19236535.9" "Tissue enhanced" "Detected in all" "skin: 155590666.0" "HPA003624, CAB062559" Enhanced Enhanced Nucleoplasm NA NA 46000 "Cluster 13: Non-specific - Mitochondria" "Cluster 15: Bone marrow - Innate immune response" "Cluster 30: White matter - Myelination" "Cluster 36: Non-specific - mRNA processing" "Cluster 97: Non-specific - Cellular respiration" 43 Nucleoplasm "CAB062559: , HPA003624: " "unprognostic (1.48e-2)" "unprognostic (1.22e-2)" "unprognostic (8.46e-2)" "unprognostic (2.34e-2)" "unprognostic (2.28e-3)" "unprognostic (5.72e-3)" "unprognostic (7.98e-2)" "unprognostic (1.18e-2)" "unprognostic (5.04e-2)" "unprognostic (4.57e-3)" "potential prognostic favorable (1.41e-10)" "unprognostic (1.34e-1)" "unprognostic (5.29e-2)" "unprognostic (8.10e-3)" "unprognostic (3.24e-2)" "unprognostic (2.47e-1)" "unprognostic (2.93e-1)" "unprognostic (3.35e-1)" "unprognostic (3.26e-1)" "unprognostic (4.80e-2)" "unprognostic (9.90e-2)" "unprognostic (2.21e-2)" "unprognostic (2.03e-1)" "unprognostic (2.25e-2)" "unprognostic (1.89e-2)" "unprognostic (5.23e-3)" "unprognostic (5.21e-2)" "unprognostic (2.09e-1)" "unprognostic (4.59e-2)" "unprognostic (4.38e-3)" "unprognostic (5.73e-3)" RBM34 KIAA0117 ENSG00000188739 "RNA binding motif protein 34" P42696 1 235131183-235161283 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 15.5;Bergmann glia: 15.7;Brain excitatory neurons: 17.5;Brain inhibitory neurons: 18.4;Choroid plexus epithelial cells: 37.7;Ependymal cells: 14.2;Microglia: 37.0;Oligodendrocyte progenitor cells: 18.7;Oligodendrocytes: 20.8;Other brain neurons: 18.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 37.7;Glial cells: 37.0;Neuronal cells: 18.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 9291730.6;T-cells: 8869213.5" "Group enriched" "Detected in some" 22499 "fallopian tube: 1427026.0;lymphoid tissue: 3072762.3" HPA028606 Approved Supported "Nucleoplasm,Nucleoli,Mitotic chromosome" Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 84 Nucleoli "Nucleoplasm, Mitotic chromosome" "HPA028606: " "unprognostic (1.28e-2)" "unprognostic (3.34e-2)" "unprognostic (1.65e-1)" "unprognostic (4.93e-3)" "unprognostic (3.14e-1)" "unprognostic (2.80e-1)" "unprognostic (1.41e-1)" "unprognostic (8.22e-3)" "unprognostic (8.72e-3)" "unprognostic (1.86e-3)" "unprognostic (9.03e-2)" "unprognostic (1.60e-1)" "unprognostic (1.64e-3)" "unprognostic (2.52e-3)" "unprognostic (9.46e-2)" "unprognostic (2.94e-2)" "unprognostic (1.41e-3)" "unprognostic (2.41e-2)" "unprognostic (2.43e-2)" "unprognostic (1.81e-2)" "unprognostic (9.20e-3)" "unprognostic (4.94e-2)" "unprognostic (5.65e-3)" "unprognostic (5.96e-2)" "unprognostic (1.56e-1)" "unprognostic (5.29e-2)" "unprognostic (2.88e-2)" "unprognostic (1.62e-1)" "unprognostic (2.98e-2)" "unprognostic (7.44e-2)" "unprognostic (1.72e-1)" RBM47 "FLJ20273, NET18" ENSG00000163694 "RNA binding motif protein 47" A0AV96 4 40423267-40630875 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 2488.6;Esophageal apical cells: 2084.0;monocytes: 1608.9;Neutrophils: 4921.4;Syncytiotrophoblasts: 1575.8;Urothelial cells: 1824.4" "Cell type enhanced" "Detected in all" "Ciliated cells: 2488.6;Neutrophils: 4921.4" "Group enriched" "Detected in all" 10 "central nervous system macrophage: 589.3;choroid plexus epithelial cell: 1934.4" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 91.9" "Immune cell enhanced" "Detected in many" "neutrophil: 136.7" "Group enriched" "Detected in many" 13 "dendritic cells: 34.4;granulocytes: 136.7;monocytes: 45.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Heart muscle - Macrophages, Prostate - Prostate glandular cells, Skeletal muscle - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal tubules: 34481188.1" "Tissue enhanced" "Detected in many" "bone marrow: 15282999.3" HPA006347 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 24: Neutrophils - Innate immunity signal integration" 16 "Nucleoplasm, Cytosol" "HPA006347: " "potential prognostic favorable (9.21e-6)" "unprognostic (2.08e-2)" "unprognostic (1.62e-2)" "unprognostic (9.10e-2)" "unprognostic (8.64e-3)" "unprognostic (1.25e-1)" "unprognostic (2.44e-2)" "unprognostic (8.89e-3)" "unprognostic (1.80e-2)" "potential prognostic unfavorable (7.59e-4)" "validated prognostic favorable (3.57e-10)" "validated prognostic favorable (2.16e-4)" "unprognostic (2.23e-3)" "unprognostic (6.01e-3)" "unprognostic (3.82e-2)" "unprognostic (2.02e-1)" "unprognostic (4.38e-1)" "unprognostic (7.70e-2)" "unprognostic (6.14e-2)" "unprognostic (1.25e-1)" "unprognostic (3.03e-1)" "unprognostic (5.89e-2)" "unprognostic (5.65e-2)" "unprognostic (2.47e-1)" "unprognostic (2.11e-2)" "unprognostic (6.89e-2)" "unprognostic (5.90e-2)" "unprognostic (2.03e-2)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (2.03e-1)" RBM48 "C7orf64, DKFZp564O0523, HSPC304" ENSG00000127993 "RNA binding motif protein 48" Q5RL73 7 92528773-92540481 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA021777, HPA025306" Uncertain Enhanced Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 27 Nucleoplasm "HPA021777: , HPA025306: " "unprognostic (6.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.24e-2)" "unprognostic (1.60e-2)" "unprognostic (1.77e-1)" "unprognostic (1.38e-2)" "unprognostic (9.66e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (3.16e-4)" "validated prognostic favorable (7.79e-4)" "validated prognostic favorable (9.14e-4)" "unprognostic (6.17e-3)" "potential prognostic unfavorable (2.07e-4)" "unprognostic (3.41e-1)" "unprognostic (1.56e-1)" "unprognostic (9.63e-2)" "unprognostic (1.15e-1)" "unprognostic (9.89e-2)" "unprognostic (4.12e-2)" "unprognostic (4.26e-2)" "unprognostic (1.29e-3)" "unprognostic (6.43e-2)" "unprognostic (4.65e-3)" "unprognostic (1.67e-1)" "unprognostic (2.66e-2)" "unprognostic (6.22e-2)" "unprognostic (3.83e-2)" "unprognostic (2.57e-2)" "unprognostic (1.86e-2)" RBMY1A1 "RBM1, RBM2, YRRM1, YRRM2" ENSG00000234414 "RNA binding motif protein Y-linked family 1 member A1" P0DJD3 Y 21534879-21549326 "Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Activator, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 80 "testis: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 3.1;liver cancer: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" 16 Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBMY1B ENSG00000242875 "RNA binding motif protein Y-linked family 1 member B" A6NDE4 Y 21511338-21525786 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 17: Neuroblastoma - Neuronal signaling" 1 Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBMY1D ENSG00000244395 "RNA binding motif protein Y-linked family 1 member D" P0C7P1 Y 21880076-21894526 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 13 "testis: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 7: Liver cancer - Metabolism" Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBMY1E ENSG00000242389 "RNA binding motif protein Y-linked family 1 member E" A6NEQ0 Y 21903618-21918042 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 26 "testis: 2.6" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 1.4;Early primary spermatocytes: 2.0" "Cell type enriched" "Detected in single" 19 "Spermatogenic cell types: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBMY1F MGC33094 ENSG00000169800 "RNA binding motif protein Y-linked family 1 member F" Q15415 Y 22168542-22182982 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 31 "testis: 3.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 22 "Myeloma: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 29 "Nucleoplasm, Nucleoli" "HPA001534: , HPA053147: , HPA057723: " RBMY1J ENSG00000226941 "RNA binding motif protein Y-linked family 1 member J" Q15415 Y 22403410-22417881 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 12 "Myeloma: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001534, HPA053147, HPA057723" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 20: Myeloma - Immune response" 29 Nucleoplasm Nucleoli "HPA001534: , HPA053147: , HPA057723: " RBP2 "CRABP-II, CRBP2, CRBPII, RBPC2" ENSG00000114113 "Retinol binding protein 2" P50120 3 139452884-139480747 "Metabolic proteins, Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 355 "intestine: 2547.7" "Cell type enriched" "Detected in many" 33 "Enterocytes: 5630.5" "Cell type enriched" "Detected in many" 33 "Enterocytes: 5630.5" "Cell type enhanced" "Detected in many" "ependymal cell: 15.5" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 12.6;Pancreatic Adenocarcinoma (TCGA): 11.1;Rectum Adenocarcinoma (TCGA): 11.1;Stomach Adenocarcinoma (TCGA): 16.9;Testicular Germ Cell Tumor (TCGA): 7.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "colorectal cancer: 8.3;liver cancer: 12.5;ovarian cancer: 21.0;Uterine cancer: 5.4" "Adrenal gland - Adrenal medulla cells, Lung - Alveolar cells type 1, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 3879 "Alveolar cell types: 244964.0;Collecting ducts: 233861.4;Large ducts: 684985.4" "Tissue enriched" "Detected in many" "intestine: 583271365.8" HPA035866 Enhanced Approved "Golgi apparatus" NA NA 700000 "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 1: Enterocytes - Absorption and Digestion" "Golgi apparatus" "HPA035866: " "unprognostic (5.31e-2)" "unprognostic (4.70e-3)" "unprognostic (1.50e-1)" "unprognostic (1.24e-1)" "unprognostic (1.01e-1)" "unprognostic (4.47e-2)" "unprognostic (2.52e-2)" "unprognostic (1.23e-1)" "unprognostic (1.26e-1)" "unprognostic (3.85e-3)" "unprognostic (1.04e-1)" "unprognostic (7.33e-2)" "unprognostic (2.13e-1)" "unprognostic (1.43e-2)" "unprognostic (4.43e-2)" "unprognostic (5.92e-2)" "unprognostic (6.80e-2)" "unprognostic (2.70e-2)" "unprognostic (4.65e-2)" RCN3 RLP49 ENSG00000142552 "Reticulocalbin 3" Q96D15 19 49528003-49546962 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 108.4;Endometrial stromal cells: 46.0;Fibroblasts: 80.8;Hepatic stellate cells: 251.7;Hofbauer cells: 44.8;Oocytes: 55.3;Ovarian stromal cells: 44.5;Peritubular myoid cells: 41.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 80.8;Stellate cells: 251.7;Stromal cells: 108.4" "Group enriched" "Detected in many" 4 "astrocyte: 6.4;central nervous system macrophage: 21.7;fibroblast: 22.3;vascular associated smooth muscle cell: 15.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 6.9" "Group enriched" "Detected in many" 9 "granulocytes: 2.6;NK-cells: 1.8;T-cells: 6.9" "Cancer enhanced" "Detected in all" "Bone cancer: 127.6;Sarcoma: 142.8" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Heart muscle - Fibroblasts, Lung - Fibroblasts_2, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Oocytes: 17608741.4;Smooth muscle cells: 19675968.2" "Tissue enhanced" "Detected in many" "ovary: 37016335.7" "HPA043134, HPA050402" Uncertain Supported "Endoplasmic reticulum,Vesicles" "Intracellular and membrane" Transport No No 3800000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 9 "Endoplasmic reticulum" Vesicles "HPA043134: , HPA050402: " "potential prognostic favorable (7.80e-4)" "unprognostic (2.14e-1)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "unprognostic (1.19e-3)" "unprognostic (6.13e-2)" "unprognostic (7.26e-3)" "unprognostic (5.47e-2)" "unprognostic (1.23e-1)" "unprognostic (7.52e-2)" "potential prognostic unfavorable (7.65e-5)" "unprognostic (8.41e-2)" "unprognostic (4.63e-2)" "potential prognostic unfavorable (9.55e-4)" "unprognostic (2.79e-2)" "unprognostic (4.23e-2)" "unprognostic (2.81e-3)" "unprognostic (1.12e-1)" "unprognostic (1.72e-1)" "unprognostic (6.08e-2)" "unprognostic (2.69e-2)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (2.14e-1)" "unprognostic (8.67e-3)" "unprognostic (3.05e-2)" "unprognostic (7.06e-2)" "unprognostic (9.48e-2)" "unprognostic (2.07e-1)" "unprognostic (4.78e-3)" "unprognostic (7.05e-3)" RCOR2 ENSG00000167771 "REST corepressor 2" Q8IZ40 11 63911230-63917164 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.2" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 10.6;Extravillous trophoblasts: 7.2;Megakaryocytes: 6.2;Neuroendocrine cells: 6.5;Retinal bipolar cells: 24.6;Syncytiotrophoblasts: 6.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 10.6;Neuronal cells: 24.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 38.1" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 2508675.6" "Not detected" "Not detected" HPA021638 Uncertain Approved Nucleoplasm,Vesicles,Midbody Yes NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 17 Nucleoplasm "Vesicles, Midbody" "HPA021638: " "unprognostic (6.26e-2)" "unprognostic (1.60e-2)" "unprognostic (9.48e-2)" "unprognostic (5.88e-2)" "unprognostic (2.26e-1)" "unprognostic (7.13e-2)" "unprognostic (1.26e-2)" "unprognostic (1.28e-3)" "unprognostic (3.38e-2)" "unprognostic (1.98e-2)" "unprognostic (5.20e-2)" "unprognostic (1.93e-2)" "unprognostic (2.98e-2)" "unprognostic (7.80e-2)" "unprognostic (6.33e-2)" "unprognostic (1.33e-1)" "unprognostic (2.85e-1)" "unprognostic (2.50e-1)" "unprognostic (3.02e-1)" "unprognostic (1.70e-2)" "unprognostic (1.12e-1)" "unprognostic (2.06e-1)" "unprognostic (2.66e-1)" "unprognostic (2.94e-2)" RDH14 "PAN2, SDR7C4" ENSG00000240857 "Retinol dehydrogenase 14" Q9HBH5 2 18554723-18560679 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA056686, HPA078577" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 108: Fibroblasts - ECM organization" 6 Nucleoplasm Cytosol "HPA056686: , HPA078577: " "unprognostic (8.42e-2)" "unprognostic (1.70e-1)" "unprognostic (1.44e-2)" "unprognostic (3.39e-1)" "unprognostic (3.04e-1)" "unprognostic (2.44e-1)" "unprognostic (4.06e-2)" "unprognostic (2.22e-1)" "unprognostic (7.57e-3)" "unprognostic (2.20e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (4.12e-2)" "unprognostic (1.53e-1)" "unprognostic (4.26e-3)" "unprognostic (3.40e-3)" "unprognostic (2.71e-2)" "unprognostic (7.66e-2)" "unprognostic (3.44e-2)" "unprognostic (1.06e-1)" "unprognostic (7.11e-2)" "unprognostic (1.54e-1)" "unprognostic (3.48e-1)" "unprognostic (3.40e-1)" "unprognostic (2.88e-1)" "unprognostic (1.50e-1)" "unprognostic (1.16e-1)" "unprognostic (2.90e-1)" "unprognostic (2.46e-1)" "unprognostic (7.84e-2)" "unprognostic (2.23e-1)" "unprognostic (2.54e-1)" RDH5 "HSD17B9, RDH1, SDR9C5" ENSG00000135437 "Retinol dehydrogenase 5" Q92781 12 55720367-55724705 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Steroid metabolism, Vision" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 88.7;liver: 55.1" "Cell type enhanced" "Detected in some" "Colonocytes: 8.0;Enteric stem cells: 3.4;Enteric transient amplifying cells: 4.3;Enterocytes: 18.3;Epididymal efferent duct absorptive cells: 7.7;Epididymal principal cells: 10.1;Gastric chief cells: 3.3;Neuroendocrine cells: 4.7;Paneth cells: 7.7;Retinal pigment epithelial cells: 17.1" "Cell type enhanced" "Detected in some" "Ductal cells: 7.7;Enterocytes: 18.3;Pigment cells: 17.1;Reproductive supporting cells: 10.1;Secretory gland support: 7.7" "Cell type enhanced" "Detected in some" "ependymal cell: 1.5;pericyte: 1.4;vascular associated smooth muscle cell: 1.6" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 39.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Hepatocytes: 2676831.3" "Group enriched" "Detected in some" 3225 "liver: 299290.6;skin: 345756.4" HPA063345 Uncertain Vesicles NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 15: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 1 Vesicles "HPA063345: " "unprognostic (4.22e-2)" "unprognostic (8.47e-3)" "unprognostic (1.47e-3)" "unprognostic (2.10e-2)" "unprognostic (3.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.13e-1)" "unprognostic (1.47e-1)" "unprognostic (1.38e-1)" "unprognostic (3.53e-3)" "unprognostic (4.62e-1)" "unprognostic (3.96e-3)" "unprognostic (1.48e-2)" "unprognostic (7.85e-3)" "unprognostic (7.61e-3)" "unprognostic (1.63e-1)" "unprognostic (9.72e-2)" "unprognostic (1.41e-1)" "unprognostic (3.68e-1)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (8.61e-2)" "unprognostic (8.78e-2)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (1.20e-2)" "unprognostic (7.77e-2)" RDH8 "PRRDH, SDR28C2" ENSG00000080511 "Retinol dehydrogenase 8" Q9NYR8 19 10013249-10022279 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Sensory transduction, Vision" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "retina: 106.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 47.6;Early spermatids: 61.3;Late primary spermatocytes: 43.1;Loop of henle epithelial cells: 51.9;Retinal bipolar cells: 25.2;Rod photoreceptor cells: 164.2" "Group enriched" "Detected in some" 14 "Neuronal cells: 164.2;Renal nephron cells: 51.9;Spermatogenic cell types: 61.3" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Skin Cutaneous Melanoma (TCGA): 6.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.0" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 367 "T-cells: 36723.5" "Not detected" "Not detected" HPA064473 Approved "Nucleoplasm,Midbody ring,Cytosol" Yes NA "Cluster 42: Retina - Visual perception" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 79: Photoreceptor cells - Phototransduction" Nucleoplasm "Midbody ring, Cytosol" "HPA064473: " "unprognostic (1.16e-2)" RDX DFNB24 ENSG00000137710 Radixin P35241 11 109864295-110296712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 146.4" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1292.9" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 1292.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Skin - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glomeruli: 129046002.3;Proximal tubules: 112335594.6" "Low tissue specificity" "Detected in all" "HPA000263, HPA000763, CAB037312" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 31000000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 18: Adrenal cortex cells - Steroidogensis" 26 "Plasma membrane" Nucleoplasm "CAB037312: , HPA000263: , HPA000763: " "unprognostic (1.97e-1)" "unprognostic (7.14e-3)" "unprognostic (2.22e-1)" "unprognostic (1.64e-2)" "unprognostic (2.71e-1)" "unprognostic (6.69e-2)" "unprognostic (2.88e-2)" "potential prognostic unfavorable (8.44e-4)" "unprognostic (2.65e-1)" "unprognostic (1.79e-2)" "potential prognostic favorable (2.99e-8)" "unprognostic (1.41e-2)" "unprognostic (5.91e-2)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (2.00e-3)" "unprognostic (1.82e-1)" "unprognostic (2.98e-1)" "unprognostic (1.79e-1)" "unprognostic (7.76e-2)" "unprognostic (2.41e-3)" "potential prognostic unfavorable (4.36e-8)" "unprognostic (1.14e-1)" "unprognostic (2.12e-1)" "unprognostic (4.38e-2)" "unprognostic (2.76e-1)" "unprognostic (3.81e-2)" "unprognostic (3.99e-1)" "unprognostic (5.74e-2)" "unprognostic (2.21e-1)" RECQL5 "FLJ90603, RecQ5" ENSG00000108469 "RecQ like helicase 5" O94762 17 75626845-75667189 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, DNA replication" "DNA-binding, Helicase, Hydrolase, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 75.5;Esophageal apical cells: 118.2;Foveolar cells: 88.1" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 118.2;Gastric glandular cells: 88.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in some" 1 "lymphoid tissue: 15661831.4" HPA029971 Supported Nucleoplasm,Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 36 Nucleoplasm Cytosol "HPA029971: " "unprognostic (4.79e-3)" "unprognostic (1.50e-1)" "unprognostic (3.27e-2)" "unprognostic (3.45e-2)" "unprognostic (3.28e-1)" "unprognostic (7.57e-2)" "unprognostic (1.15e-1)" "unprognostic (4.60e-3)" "unprognostic (1.38e-1)" "unprognostic (2.50e-2)" "unprognostic (1.41e-1)" "unprognostic (7.31e-2)" "unprognostic (8.23e-2)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.12e-1)" "unprognostic (2.65e-3)" "unprognostic (1.43e-1)" "unprognostic (6.59e-3)" "unprognostic (2.59e-3)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (2.76e-2)" "unprognostic (1.00e-3)" "potential prognostic favorable (1.53e-5)" "unprognostic (2.68e-1)" "unprognostic (1.74e-1)" "unprognostic (3.05e-1)" "unprognostic (3.20e-1)" "unprognostic (8.20e-2)" REEP6 "C19orf32, DP1L1, FLJ25383, Yip2f" ENSG00000115255 "Receptor accessory protein 6" Q96HR9 19 1491166-1497927 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 204.5;liver: 523.4;testis: 363.6" "Cell type enriched" "Detected in many" 7 "Late spermatids: 5757.5" "Cell type enriched" "Detected in many" 7 "Spermatogenic cell types: 5757.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Liver Hepatocellular Carcinoma (TCGA): 267.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Late spermatids" "Cell type enhanced" "Detected in many" "Granulosa cells: 66783918.4;Hepatocytes: 112116320.2" "Tissue enriched" "Detected in many" "liver: 84127176.9" "HPA003895, HPA048015" Enhanced Supported "Endoplasmic reticulum,Acrosome" NA NA 6800 "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 49 "Endoplasmic reticulum" Acrosome "HPA003895: , HPA048015: " "unprognostic (1.33e-2)" "unprognostic (1.86e-1)" "unprognostic (1.12e-2)" "unprognostic (1.63e-1)" "unprognostic (7.74e-2)" "unprognostic (4.94e-2)" "unprognostic (1.92e-1)" "unprognostic (9.23e-2)" "unprognostic (4.26e-2)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.59e-2)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "unprognostic (7.71e-2)" "unprognostic (4.20e-3)" "unprognostic (3.30e-2)" "unprognostic (6.73e-2)" "unprognostic (6.08e-1)" "unprognostic (2.97e-1)" "potential prognostic unfavorable (5.39e-4)" "unprognostic (4.40e-2)" "unprognostic (1.51e-2)" "unprognostic (2.35e-1)" "unprognostic (7.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.72e-2)" "unprognostic (2.58e-1)" "unprognostic (1.15e-1)" "unprognostic (7.28e-2)" "unprognostic (5.24e-2)" RER1 ENSG00000157916 "Retention in endoplasmic reticulum sorting receptor 1" O15258 1 2391775-2405442 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1550.1;Late primary spermatocytes: 593.7;Late spermatids: 653.0;Syncytiotrophoblasts: 612.2" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1550.1;Spermatogenic cell types: 653.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "intestine: 18830363.0" "CAB037240, HPA051400" Supported Supported "Golgi apparatus" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 84: Apical squamous epithelium - Cornification" 74 "Golgi apparatus" "CAB037240: , HPA051400: " "unprognostic (1.62e-2)" "unprognostic (1.95e-1)" "unprognostic (7.22e-2)" "unprognostic (3.41e-3)" "potential prognostic favorable (1.19e-4)" "unprognostic (9.73e-2)" "unprognostic (1.83e-1)" "unprognostic (2.97e-1)" "unprognostic (6.63e-3)" "potential prognostic unfavorable (2.15e-4)" "potential prognostic favorable (3.32e-4)" "unprognostic (2.51e-1)" "unprognostic (4.48e-1)" "unprognostic (3.59e-3)" "unprognostic (1.39e-3)" "unprognostic (1.53e-2)" "unprognostic (2.50e-2)" "unprognostic (9.31e-2)" "unprognostic (9.66e-2)" "unprognostic (3.75e-1)" "unprognostic (1.56e-1)" "unprognostic (3.95e-3)" "unprognostic (1.34e-1)" "unprognostic (2.49e-1)" "unprognostic (1.09e-1)" "unprognostic (3.42e-1)" "unprognostic (1.97e-1)" "unprognostic (1.55e-1)" "unprognostic (2.35e-2)" "unprognostic (4.44e-1)" "unprognostic (1.65e-1)" RERE "ARG, ARP, ATN1L, ATN2, DNB1, KIAA0458" ENSG00000142599 "Arginine-glutamic acid dipeptide repeats" Q9P2R6 1 8352397-8848921 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 946083.4" "Tissue enriched" "Detected in many" "cerebral cortex: 8796730.0" HPA024093 Uncertain Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 17 "Nuclear bodies" Nucleoplasm "HPA024093: " "unprognostic (1.77e-2)" "unprognostic (2.11e-1)" "unprognostic (1.85e-2)" "unprognostic (7.29e-3)" "unprognostic (2.03e-2)" "unprognostic (3.38e-2)" "unprognostic (2.56e-1)" "potential prognostic favorable (8.83e-4)" "unprognostic (1.16e-2)" "unprognostic (1.16e-2)" "potential prognostic favorable (3.39e-6)" "unprognostic (2.51e-3)" "unprognostic (3.27e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (8.13e-2)" "unprognostic (3.78e-2)" "unprognostic (1.87e-1)" "unprognostic (4.03e-2)" "unprognostic (2.08e-1)" "unprognostic (9.96e-2)" "unprognostic (1.89e-1)" "unprognostic (1.23e-1)" "unprognostic (9.75e-3)" "unprognostic (2.62e-1)" "unprognostic (2.26e-1)" "unprognostic (4.37e-3)" "unprognostic (5.19e-2)" "unprognostic (3.02e-1)" "unprognostic (1.59e-1)" "unprognostic (3.81e-1)" "unprognostic (1.75e-1)" RERG MGC15754 ENSG00000134533 "RAS like estrogen regulated growth inhibitor" Q96A58 12 15107783-15348675 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 401.4;Mesothelial cells: 412.0;Pericytes: 407.0;Podocytes: 1212.0;Proximal tubule cells: 508.1;Salivary ionocytes: 493.3" "Cell type enhanced" "Detected in many" "Ionocytes: 493.3;Renal nephron cells: 1212.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 63.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 25.3;Rhabdoid: 31.9" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Lung - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Fallopian tube cells: 447136.3;Glomeruli: 438938.3;Pancreas epithelial cells: 589096.9" "Group enriched" "Detected in many" "lymphoid tissue: 379180.5;Stomach: 1034197.5" HPA041387 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 1 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center" "HPA041387: " "unprognostic (4.47e-2)" "unprognostic (1.12e-1)" "unprognostic (1.31e-1)" "unprognostic (2.58e-1)" "unprognostic (4.32e-2)" "unprognostic (3.94e-1)" "unprognostic (1.31e-1)" "unprognostic (4.91e-2)" "unprognostic (2.70e-3)" "unprognostic (2.77e-2)" "potential prognostic favorable (2.97e-4)" "unprognostic (2.42e-2)" "unprognostic (1.16e-2)" "unprognostic (1.62e-1)" "unprognostic (1.98e-1)" "unprognostic (1.69e-2)" "unprognostic (3.44e-1)" "unprognostic (1.41e-1)" "unprognostic (1.36e-1)" "unprognostic (1.54e-2)" "unprognostic (2.52e-1)" "unprognostic (6.53e-2)" "unprognostic (1.01e-1)" "unprognostic (2.41e-1)" "unprognostic (2.31e-1)" "unprognostic (7.49e-2)" "unprognostic (2.28e-2)" "unprognostic (1.09e-3)" "unprognostic (8.12e-2)" "unprognostic (4.69e-1)" "unprognostic (2.29e-2)" RERGL FLJ22655 ENSG00000111404 "RERG like" Q9H628 12 18080869-18320107 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in many" 4 "blood vessel: 166.7" "Cell type enriched" "Detected in many" 18 "Vascular smooth muscle cells: 850.4" "Cell type enriched" "Detected in many" 18 "Mural cells: 850.4" "Group enriched" "Detected in many" 5 "pericyte: 799.9;vascular associated smooth muscle cell: 330.2" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 4.0;Sarcoma: 3.2" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Heart muscle - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA041740 Uncertain Approved Nucleoplasm NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" Nucleoplasm "HPA041740: " "unprognostic (1.24e-1)" "unprognostic (5.94e-2)" "unprognostic (1.18e-2)" "unprognostic (1.75e-1)" "validated prognostic favorable (5.69e-5)" "validated prognostic favorable (2.94e-6)" "unprognostic (2.67e-3)" "potential prognostic favorable (5.51e-4)" "unprognostic (1.61e-2)" "unprognostic (7.20e-2)" "unprognostic (1.14e-1)" "unprognostic (1.72e-1)" "unprognostic (8.36e-3)" "unprognostic (3.00e-2)" "unprognostic (3.15e-1)" "unprognostic (1.70e-2)" RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 10.9;parathyroid gland: 18.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 234.0;Breast lactating cells: 62.8;Corticotrophs: 36.2;Fibro-adipogenic progenitors: 52.0;Myosatellite cells: 24.1;Respiratory ionocytes: 86.4;Retinal horizontal cells: 86.1" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 234.0;Ionocytes: 86.4;Neuronal cells: 86.1;Secretory cells: 62.8" "Cell type enhanced" "Detected in many" "lower rhombic lip: 23.0" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 20.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Neuroblastoma: 97.7;thyroid cancer: 31.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 86.5;spinal cord: 33.3" "Cell type enriched" "Detected in single" 170 "Macrophages: 16958.8" "Tissue enriched" "Detected in single" 4497 "blood vessel: 449739.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 14000000 "Cluster 69: Parathyroid gland - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 53 "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: , HPA008356: , HPA008495: " "unprognostic (7.24e-2)" "unprognostic (1.86e-1)" "unprognostic (3.21e-1)" "unprognostic (1.61e-1)" "unprognostic (5.47e-2)" "unprognostic (6.93e-3)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (1.31e-2)" "unprognostic (4.72e-1)" "unprognostic (9.61e-2)" "unprognostic (1.17e-3)" "unprognostic (2.46e-2)" "unprognostic (5.02e-2)" "unprognostic (2.85e-1)" RFC3 "MGC5276, RFC38" ENSG00000133119 "Replication factor C subunit 3" P40938 13 33818069-33966558 "Essential proteins, Predicted intracellular proteins" "DNA replication" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 159.0;Early primary spermatocytes: 133.2;Erythrocyte progenitors: 182.3;Undifferentiated spermatogonia: 151.9" "Cell type enhanced" "Detected in many" "Erythrocytes: 182.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 4733455.3" "Group enriched" "Detected in many" "fallopian tube: 568098.3;intestine: 947189.4;lymphoid tissue: 1374032.5" HPA030149 Approved Supported Nucleoplasm,Vesicles No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 51 "Nucleoplasm, Vesicles" "HPA030149: " "unprognostic (3.07e-3)" "unprognostic (5.89e-2)" "unprognostic (2.05e-2)" "unprognostic (5.28e-2)" "unprognostic (1.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.05e-2)" "unprognostic (3.34e-2)" "unprognostic (2.03e-2)" "potential prognostic unfavorable (4.55e-5)" "potential prognostic favorable (7.14e-5)" "unprognostic (1.15e-1)" "unprognostic (7.24e-2)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (5.97e-5)" "unprognostic (4.37e-3)" "potential prognostic unfavorable (1.23e-4)" "unprognostic (1.50e-1)" "unprognostic (1.73e-1)" "unprognostic (6.49e-2)" "unprognostic (9.73e-2)" "unprognostic (2.89e-2)" "potential prognostic unfavorable (4.05e-4)" "unprognostic (1.56e-1)" "unprognostic (5.54e-2)" "unprognostic (1.23e-3)" "unprognostic (2.91e-3)" "unprognostic (4.21e-2)" "unprognostic (4.69e-1)" "unprognostic (2.91e-1)" "unprognostic (4.43e-2)" RFNG ENSG00000169733 "RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase" Q9Y644 17 82047902-82051831 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 70.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA011564, HPA031673" Uncertain Approved Nucleoplasm No No 200000 "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 1 Nucleoplasm "HPA011564: , HPA031673: " "unprognostic (4.02e-2)" "unprognostic (1.58e-1)" "unprognostic (4.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.78e-2)" "unprognostic (1.97e-1)" "unprognostic (1.86e-2)" "unprognostic (1.89e-2)" "unprognostic (2.53e-1)" "unprognostic (3.20e-2)" "potential prognostic favorable (2.16e-5)" "unprognostic (1.13e-1)" "unprognostic (1.76e-1)" "unprognostic (2.07e-1)" "unprognostic (1.26e-2)" "unprognostic (4.59e-2)" "unprognostic (2.09e-2)" "unprognostic (9.29e-3)" "unprognostic (2.21e-1)" "unprognostic (4.25e-1)" "unprognostic (3.12e-3)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "potential prognostic favorable (8.50e-4)" "unprognostic (1.70e-2)" "unprognostic (2.71e-3)" "unprognostic (1.14e-2)" "unprognostic (1.14e-2)" "unprognostic (2.87e-1)" "unprognostic (8.76e-2)" "unprognostic (1.26e-1)" RFPL1 RNF78 ENSG00000128250 "Ret finger protein like 1" O75677 22 29438583-29442455 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 16.4" "Group enriched" "Detected in some" 6 "Early spermatids: 10.4;Late primary spermatocytes: 2.8;Prostatic glandular cells: 9.5;Retinal ganglion cells: 3.9" "Group enriched" "Detected in some" 10 "Glandular cells: 9.5;Neuronal cells: 3.9;Spermatogenic cell types: 10.4" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Prostate Adenocarcinoma (TCGA): 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 1: Neuronal - Visual perception" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "Nuclear speckles" "Plasma membrane" "HPA048320: , HPA072380: " "unprognostic (2.08e-1)" "unprognostic (4.58e-2)" "unprognostic (2.34e-1)" RFPL2 RNF79 ENSG00000128253 "Ret finger protein like 2" O75678 22 32190435-32205073 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 4.3;prostate: 3.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 12.1;Brain inhibitory neurons: 8.6;Erythrocyte progenitors: 5.5;Other brain neurons: 4.8;Pancreatic islet cells: 4.2;Prostatic glandular cells: 27.4;Retinal amacrine cells: 6.6;Retinal bipolar cells: 3.2" "Cell type enhanced" "Detected in some" "Erythrocytes: 5.5;Glandular cells: 27.4;Neuronal cells: 12.1" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 48.3" "Cancer enriched" "Detected in single" 5 "Prostate Adenocarcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "prostate cancer: 1.3" "Prostate - Prostate glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046608, HPA048320, HPA072380" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" "Nuclear speckles" "Plasma membrane" "HPA046608: , HPA048320: , HPA072380: " "unprognostic (1.36e-1)" "unprognostic (1.01e-1)" RFPL3 RNF120 ENSG00000128276 "Ret finger protein like 3" O75679 22 32354885-32361161 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 23.3" "Group enriched" "Detected in some" 5 "Early spermatids: 3.3;Epicardial cells: 4.5;Late primary spermatocytes: 8.1;Undifferentiated spermatogonia: 9.1" "Group enriched" "Detected in some" 7 "Barrier epithelial cells: 4.5;Spermatogenic cell types: 9.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 2.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Myeloma: 2.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "Nuclear speckles" "Plasma membrane" "HPA048320: , HPA072380: " "unprognostic (3.30e-2)" "unprognostic (9.10e-3)" "unprognostic (3.52e-1)" RFWD3 "FANCW, FLJ10520, RNF201" ENSG00000168411 "Ring finger and WD repeat domain 3" Q6PCD5 16 74621399-74666877 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 44.9" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 117.2;Erythrocyte progenitors: 98.0;Monocyte progenitors: 91.4;Neutrophil progenitors: 119.7" "Cell type enhanced" "Detected in all" "Neutrophils: 119.7;Spermatogenic cell types: 117.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048258, HPA075649" Approved Enhanced Nucleoplasm,Cytosol No No "Cluster 15: NK-cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 39 Nucleoplasm Cytosol "HPA048258: , HPA075649: " "unprognostic (2.36e-1)" "unprognostic (4.07e-2)" "unprognostic (4.36e-1)" "unprognostic (2.09e-1)" "unprognostic (1.27e-1)" "unprognostic (3.23e-1)" "unprognostic (3.13e-1)" "unprognostic (5.16e-2)" "unprognostic (3.46e-1)" "unprognostic (1.35e-2)" "potential prognostic favorable (2.81e-4)" "unprognostic (6.99e-2)" "unprognostic (1.60e-2)" "unprognostic (7.70e-3)" "potential prognostic unfavorable (3.90e-4)" "unprognostic (8.19e-3)" "unprognostic (1.88e-2)" "unprognostic (1.80e-1)" "unprognostic (8.03e-3)" "unprognostic (7.82e-2)" "unprognostic (3.78e-3)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (1.50e-5)" "unprognostic (4.81e-2)" "unprognostic (1.68e-2)" "unprognostic (2.64e-1)" "unprognostic (3.97e-2)" "unprognostic (2.88e-1)" "unprognostic (3.00e-1)" "unprognostic (8.03e-2)" "unprognostic (5.57e-2)" RFX3 ENSG00000080298 "Regulatory factor X3" P48380 9 3218297-3526004 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 19.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1558.8;Endometrial ciliated cells: 852.2;Ependymal cells: 2321.0;Neuroendocrine cells: 852.7;Respiratory ciliated cells: 1764.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 2321.0" "Cell type enhanced" "Detected in all" "ependymal cell: 2704.1;hippocampal dentate gyrus: 2844.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 2050389.5;Neurons: 826809.9" "Tissue enriched" "Detected in single" 2160 "fallopian tube: 215990.3" HPA035689 Enhanced Supported "Nucleoplasm,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 18 Nucleoplasm "Golgi apparatus, Vesicles, Cytosol" "HPA035689: " "unprognostic (2.31e-1)" "unprognostic (3.25e-3)" "unprognostic (2.30e-1)" "unprognostic (4.84e-1)" "unprognostic (7.52e-3)" "unprognostic (2.02e-2)" "unprognostic (8.33e-2)" "unprognostic (6.26e-2)" "unprognostic (1.72e-1)" "unprognostic (1.13e-1)" "unprognostic (6.36e-3)" "potential prognostic favorable (2.86e-4)" "unprognostic (6.70e-2)" "unprognostic (9.33e-2)" "unprognostic (6.31e-3)" "unprognostic (9.12e-2)" "unprognostic (1.26e-1)" "unprognostic (3.03e-1)" "unprognostic (1.98e-1)" "unprognostic (9.61e-2)" "unprognostic (3.06e-2)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (1.64e-1)" "unprognostic (4.88e-3)" "unprognostic (2.64e-2)" "unprognostic (1.19e-1)" "unprognostic (2.16e-1)" "unprognostic (9.52e-2)" "unprognostic (4.22e-2)" "unprognostic (1.64e-1)" RGCC "bA157L14.2, C13orf15, RGC-32, RGC32" ENSG00000102760 "Regulator of cell cycle" Q9H4X1 13 41457550-41470871 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 391.7;lung: 668.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 384.3;Bergmann glia: 482.7;Breast lactating cells: 544.0;Breast secretory cells: 542.6;cDC: 375.2;Fallopian tube ciliated cells: 330.4;Hofbauer cells: 374.1;Innate lymphoid cells: 333.5;Late primary spermatocytes: 342.1;Neutrophil progenitors: 439.7;Schwann cells: 509.0;T-cells: 437.0;Vascular endothelial cells: 439.0" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 596.0;endothelial cell: 312.4;oligodendrocyte: 207.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 160.9;T-reg: 91.1" "Lineage enriched" "Detected in many" 15 "T-cells: 160.9" "Cancer enhanced" "Detected in many" "lymphoma: 34.0" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 2208926.3;Capillaries: 663914.1" "Tissue enhanced" "Detected in many" "bone marrow: 9557707.4" "HPA035638, HPA063701" Enhanced Supported Nucleoplasm,Nucleoli No No 870000 "Cluster 31: T-cells - T-cell receptor" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 3 Nucleoplasm Nucleoli "HPA035638: , HPA063701: " "unprognostic (1.08e-1)" "unprognostic (5.66e-3)" "unprognostic (1.65e-1)" "unprognostic (1.37e-2)" "unprognostic (1.10e-1)" "unprognostic (6.05e-2)" "unprognostic (6.16e-2)" "unprognostic (2.75e-1)" "unprognostic (2.41e-1)" "validated prognostic favorable (3.81e-11)" "validated prognostic favorable (3.68e-4)" "unprognostic (2.50e-1)" "potential prognostic favorable (5.37e-4)" "unprognostic (2.73e-3)" "unprognostic (3.25e-2)" "unprognostic (1.33e-3)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (4.69e-4)" "unprognostic (3.08e-2)" "unprognostic (1.15e-1)" "unprognostic (2.47e-1)" "unprognostic (1.70e-1)" "unprognostic (1.82e-2)" "unprognostic (2.35e-2)" "unprognostic (3.73e-2)" "unprognostic (7.08e-3)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (9.80e-2)" RGR RP44 ENSG00000148604 "Retinal G protein coupled receptor" P47804 10 84230666-84259960 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "choroid plexus: 32.4;retina: 129.0" "Group enriched" "Detected in some" 28 "Müller glia: 1640.1;Retinal pigment epithelial cells: 2638.8" "Group enriched" "Detected in some" 28 "Glial cells: 1640.1;Pigment cells: 2638.8" "Group enriched" "Detected in some" 11 "astrocyte: 22.7;Bergmann glia: 13.0;choroid plexus epithelial cell: 8.1;committed oligodendrocyte precursor: 27.1;oligodendrocyte precursor cell: 7.2" "Cancer enriched" "Detected in single" 4 "Glioblastoma Multiforme (TCGA): 3.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "breast cancer: 1.2" "Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "midbrain: 25.5;olfactory bulb: 55.9;thalamus: 29.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA059149 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" 3 Vesicles "Plasma membrane, Cytosol" "HPA059149: " "unprognostic (4.02e-2)" "unprognostic (1.57e-1)" "unprognostic (4.79e-3)" "unprognostic (8.65e-2)" RGS10 ENSG00000148908 "Regulator of G protein signaling 10" O43665 10 119499817-119542719 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 207.4" "Cell type enhanced" "Detected in many" "cDC: 404.6;Esophageal apical cells: 462.9;Hofbauer cells: 876.2;Megakaryocytes: 1551.6;Microglia: 334.6;Platelets: 4189.4" "Cell type enhanced" "Detected in many" "Megakaryocytes: 1551.6;Mononuclear phagocytes: 876.2;Platelets: 4189.4" "Cell type enriched" "Detected in many" 8 "central nervous system macrophage: 404.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Macrophages, Heart muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 4796454.6" "Tissue enhanced" "Detected in many" "bone marrow: 14317828.5" "CAB004559, HPA021305" Enhanced Supported Supported "Nucleoplasm,Nuclear bodies" NA NA 2000000 "Cluster 33: Non-specific - ATP binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 49: HMC-1 - Innate immune response" "Cluster 47: Platelets - Hemostasis" 3 Nucleoplasm "Nuclear bodies" "CAB004559: , HPA021305: " "unprognostic (2.04e-1)" "unprognostic (9.48e-2)" "unprognostic (6.05e-3)" "unprognostic (2.99e-2)" "unprognostic (1.53e-2)" "unprognostic (4.06e-2)" "unprognostic (1.47e-1)" "unprognostic (5.15e-2)" "unprognostic (2.06e-2)" "unprognostic (1.24e-1)" "unprognostic (3.33e-3)" "unprognostic (1.25e-1)" "unprognostic (9.41e-2)" "unprognostic (1.44e-3)" "unprognostic (2.44e-1)" "unprognostic (2.85e-1)" "potential prognostic unfavorable (6.62e-5)" "unprognostic (6.30e-2)" "unprognostic (2.10e-2)" "unprognostic (2.40e-2)" "unprognostic (8.60e-2)" "unprognostic (4.55e-3)" "unprognostic (6.51e-2)" "unprognostic (2.59e-1)" "unprognostic (1.09e-1)" "unprognostic (9.00e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (2.93e-1)" "unprognostic (1.08e-1)" "unprognostic (9.63e-2)" "unprognostic (1.76e-2)" RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 11.8;retina: 16.1;skeletal muscle: 8.4" "Group enriched" "Detected in some" 4 "Cone photoreceptor cells: 35.2;Retinal bipolar cells: 17.0;Retinal pigment epithelial cells: 38.4;Rod photoreceptor cells: 37.2" "Group enriched" "Detected in some" 5 "Neuronal cells: 37.2;Pigment cells: 38.4" "Cell type enriched" "Detected in single" 7 "choroid plexus epithelial cell: 5.0" "Not detected" "Not detected" "Region enriched" "Detected in all" 8 "choroid plexus: 62.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA049791 Enhanced Approved "Nucleoli,Plasma membrane,Mid piece,Principal piece,End piece" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoli, Mid piece, Principal piece, End piece" "HPA049791: " "unprognostic (2.51e-2)" RHBDL1 "RHBDL, RRP" ENSG00000103269 "Rhomboid like 1" O75783 16 675671-678268 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 36.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 38.2;Brain inhibitory neurons: 35.6;Corticotrophs: 36.6;Epididymal basal cells: 39.0;Epididymal principal cells: 28.1;Other brain neurons: 47.0;Respiratory basal cells: 18.4;Retinal amacrine cells: 29.4" "Cell type enhanced" "Detected in many" "Basal cells: 39.0;Neuronal cells: 47.0;Pituitary endocrine cells: 36.6;Reproductive supporting cells: 28.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030359, HPA030360, HPA046593" Uncertain Approved Nucleoplasm No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 27: Cerebellum - Synaptic function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 98: Neurons - Neurotransmission & signaling" 9 Nucleoplasm "HPA030359: , HPA030360: , HPA046593: " "unprognostic (3.38e-2)" "unprognostic (1.39e-2)" "unprognostic (8.59e-2)" "unprognostic (7.20e-2)" "unprognostic (2.05e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (3.53e-2)" "unprognostic (1.92e-1)" "unprognostic (1.42e-2)" "unprognostic (1.11e-1)" "unprognostic (1.72e-1)" "unprognostic (2.16e-2)" "unprognostic (3.51e-1)" "unprognostic (3.11e-3)" "unprognostic (7.87e-2)" "unprognostic (2.52e-1)" "unprognostic (1.69e-1)" "unprognostic (2.40e-1)" "unprognostic (1.83e-1)" "unprognostic (3.17e-3)" "unprognostic (5.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.49e-1)" "unprognostic (1.11e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-2)" "unprognostic (1.35e-2)" "unprognostic (5.35e-2)" "unprognostic (2.99e-1)" "unprognostic (3.43e-2)" RHEX "C1orf186, FLJ16052" ENSG00000263961 "Regulator of hemoglobinization and erythroid cell expansion" Q6ZWK4 1 206053173-206102449 "Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 22.9" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 393.8;Endometrial glandular cells: 1237.2;Endometrial luminal cells: 1014.0;Endometrial secretory cells: 295.3;Loop of henle epithelial cells: 312.3;Mast cells: 699.4;Papillary tip epithelial cells: 637.1;Proximal tubule cells: 1184.9;Renal collecting duct principal cells: 330.2" "Cell type enhanced" "Detected in many" "Glandular cells: 1237.2;Luminal cells: 1014.0;Mast cells: 699.4;Renal nephron cells: 1184.9" "Cell type enhanced" "Detected in single" "leukocyte: 2.0" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 130.9" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 152 "basophil: 1318.2" "Lineage enriched" "Detected in single" 1550 "granulocytes: 1318.2" "Cancer enhanced" "Detected in many" "Leukemia: 58.2" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Colon - Mast cells, Minor Salivary Gland - Mast cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA037859 Supported "Plasma membrane" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 22: Epididymis - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 51: Secretory epithelial cells - Mixed function" 6 "Plasma membrane" "HPA037859: " "unprognostic (3.71e-2)" "unprognostic (9.18e-2)" "unprognostic (2.39e-1)" "unprognostic (2.58e-1)" "unprognostic (1.29e-2)" "unprognostic (1.76e-2)" "unprognostic (2.50e-2)" "unprognostic (1.61e-3)" "unprognostic (1.29e-1)" "potential prognostic favorable (2.67e-5)" "unprognostic (9.00e-2)" "unprognostic (2.65e-1)" "unprognostic (7.30e-2)" "unprognostic (7.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.08e-2)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (4.61e-4)" "unprognostic (1.41e-1)" "unprognostic (2.08e-1)" "unprognostic (3.23e-1)" RHOBTB2 "DBC2, KIAA0717" ENSG00000008853 "Rho related BTB domain containing 2" Q9BYZ6 8 22987417-23020509 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 163.4;Alveolar cells type 2: 230.2;Enterocytes: 74.9;Epicardial cells: 141.0;Podocytes: 89.3;Transitional alveolar cells: 124.2" "Cell type enhanced" "Detected in many" "Alveolar cells: 230.2;Barrier epithelial cells: 141.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 2, Minor Salivary Gland - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2709 "intestine: 270899.7" HPA060938 Approved Approved "Plasma membrane" NA NA "Cluster 32: Basophils - Transcription" "Cluster 73: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 81: Alveolar cells - Lung function" 7 "Plasma membrane" "HPA060938: " "unprognostic (3.61e-3)" "unprognostic (1.38e-3)" "unprognostic (1.03e-1)" "unprognostic (2.85e-2)" "unprognostic (1.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.02e-2)" "unprognostic (8.71e-2)" "unprognostic (5.93e-2)" "unprognostic (2.57e-2)" "validated prognostic favorable (7.98e-7)" "validated prognostic favorable (5.56e-4)" "unprognostic (1.61e-1)" "unprognostic (7.31e-2)" "unprognostic (1.09e-1)" "unprognostic (7.28e-3)" "unprognostic (5.92e-2)" "unprognostic (2.06e-3)" "unprognostic (4.81e-2)" "unprognostic (1.28e-2)" "unprognostic (4.75e-2)" "unprognostic (9.21e-2)" "unprognostic (2.31e-2)" "potential prognostic favorable (7.00e-4)" "unprognostic (4.10e-1)" "unprognostic (4.00e-2)" "unprognostic (3.55e-2)" "unprognostic (2.29e-1)" "unprognostic (2.80e-1)" "unprognostic (5.42e-2)" "unprognostic (1.02e-1)" RHOQ "ARHQ, RASL7A, TC10" ENSG00000119729 "Ras homolog family member Q" P17081 2 46541806-46584688 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 169.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 244.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 1.5;classical monocyte: 2.5;eosinophil: 4.2;intermediate monocyte: 2.7;memory B-cell: 1.8;myeloid DC: 1.6;naive B-cell: 2.4;neutrophil: 4.9;non-classical monocyte: 2.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Capillaries: 185368.7;Cardiomyocytes: 78024.3" "Group enriched" "Detected in some" "cerebral cortex: 113485.5;fallopian tube: 47276.8" HPA044938 Approved Vesicles,Cytosol No No "Cluster 2: Dendritic cells - Unknown function" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 103: Non-specific - Basic cellular processes" 13 "Vesicles, Cytosol" "HPA044938: " "unprognostic (1.89e-1)" "unprognostic (1.64e-1)" "unprognostic (1.51e-2)" "unprognostic (9.79e-2)" "unprognostic (5.59e-2)" "unprognostic (1.76e-1)" "unprognostic (2.19e-2)" "unprognostic (6.42e-3)" "unprognostic (1.98e-2)" "unprognostic (1.72e-2)" "potential prognostic unfavorable (5.53e-4)" "unprognostic (1.29e-2)" "unprognostic (5.03e-1)" "potential prognostic unfavorable (1.55e-4)" "unprognostic (4.29e-2)" "unprognostic (8.98e-2)" "unprognostic (2.35e-1)" "unprognostic (7.87e-2)" "unprognostic (2.33e-1)" "unprognostic (1.29e-1)" "unprognostic (4.57e-1)" "unprognostic (2.09e-1)" "unprognostic (6.28e-2)" "unprognostic (3.07e-1)" "unprognostic (1.09e-1)" "unprognostic (1.85e-2)" "unprognostic (1.18e-1)" "unprognostic (2.32e-3)" "unprognostic (1.52e-1)" "unprognostic (9.19e-3)" "unprognostic (1.03e-2)" RHOU "ARHU, CDC42L1, DJ646B12.2, fJ646B12.2, FLJ10616, hG28K, WRCH-1, WRCH1" ENSG00000116574 "Ras homolog family member U" Q7L0Q8 1 228735479-228746664 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 67.0" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 189.0" "Cell type enriched" "Detected in many" 5 "Glial cells: 189.0" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 85.1;oligodendrocyte: 231.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA049592 Approved Uncertain "Microtubules,Primary cilium" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 34: Testis cancer - Unknown function" "Cluster 80: Oligodendrocytes - Myelination" 15 Microtubules "Primary cilium" "HPA049592: " "unprognostic (8.71e-3)" "unprognostic (8.42e-2)" "unprognostic (1.61e-2)" "unprognostic (1.37e-1)" "unprognostic (1.38e-2)" "unprognostic (1.88e-2)" "unprognostic (7.78e-3)" "unprognostic (4.12e-1)" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "validated prognostic favorable (3.22e-8)" "validated prognostic favorable (2.17e-4)" "unprognostic (2.84e-3)" "unprognostic (6.18e-2)" "unprognostic (3.22e-2)" "unprognostic (3.09e-1)" "unprognostic (9.07e-3)" "unprognostic (1.05e-1)" "unprognostic (2.00e-2)" "unprognostic (2.12e-1)" "unprognostic (3.65e-1)" "unprognostic (7.97e-2)" "unprognostic (7.58e-2)" "unprognostic (6.32e-2)" "unprognostic (1.85e-1)" "unprognostic (3.04e-1)" "unprognostic (4.75e-1)" "unprognostic (1.13e-1)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" RHOXF2 "CT107, PEPP-2, PEPP2, THG1" ENSG00000131721 "Rhox homeobox family member 2" Q9BQY4 X 120158613-120165630 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 3.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 5.8;Differentiating spermatogonia: 1.4;Epicardial cells: 2.3;Undifferentiated spermatogonia: 1.9" "Group enriched" "Detected in some" 6 "Barrier epithelial cells: 2.3;Myocytes: 5.8;Spermatogenic cell types: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Leukemia: 3.9;Myeloma: 10.9" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003314, CAB020794" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 70 "Plasma membrane" Nucleoplasm "CAB020794: , HPA003314: " RHOXF2B ENSG00000203989 "Rhox homeobox family member 2B" P0C7M4 X 120072264-120077690 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 119 "testis: 28.1" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 7.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Gastric cancer: 17.4;Leukemia: 33.6;Myeloma: 37.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA003314 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Plasma membrane" Nucleoplasm "HPA003314: " "unprognostic (1.39e-2)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (1.92e-1)" RIF1 "FLJ10599, FLJ12870" ENSG00000080345 "Replication timing regulatory factor 1" Q5UIP0 2 151409883-151508013 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 8 "Myonuclei: 3994.3" "Cell type enriched" "Detected in all" 8 "Myocytes: 3994.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "fallopian tube: 7188446.9;intestine: 5125050.2" "HPA036887, HPA036888" Supported Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 39 Nucleoplasm "Nuclear membrane, Plasma membrane" "HPA036887: , HPA036888: " "unprognostic (1.66e-1)" "unprognostic (1.39e-1)" "unprognostic (7.42e-2)" "unprognostic (6.55e-2)" "unprognostic (6.43e-2)" "unprognostic (9.86e-2)" "unprognostic (1.41e-1)" "unprognostic (7.73e-2)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (2.73e-4)" "potential prognostic favorable (1.71e-4)" "unprognostic (4.69e-3)" "unprognostic (1.09e-1)" "unprognostic (5.69e-2)" "unprognostic (2.51e-2)" "unprognostic (9.82e-3)" "unprognostic (2.05e-2)" "unprognostic (1.79e-2)" "unprognostic (9.48e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (8.79e-4)" "unprognostic (1.21e-3)" "unprognostic (6.27e-2)" "unprognostic (1.21e-1)" "unprognostic (1.01e-2)" "unprognostic (3.19e-2)" "unprognostic (2.07e-1)" "unprognostic (7.72e-2)" "unprognostic (1.25e-2)" "unprognostic (1.70e-1)" RIGI "DDX58, DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1" ENSG00000107201 "RNA sensor RIG-I" O95786 9 32455302-32526208 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 37.2;Bergmann glia: 34.6;Brain excitatory neurons: 21.1;Brain inhibitory neurons: 19.0;Choroid plexus epithelial cells: 35.6;Distal convoluted tubule cells: 24.7;Ependymal cells: 32.4;Loop of henle epithelial cells: 32.9;Microglia: 62.3;Oligodendrocyte progenitor cells: 46.0;Oligodendrocytes: 26.3;Other brain neurons: 34.3;Papillary tip epithelial cells: 36.3;Podocytes: 31.2;Proximal tubule cells: 47.0;Renal collecting duct intercalated cells: 27.8;Renal collecting duct principal cells: 41.1;Renal connecting tubule cells: 27.1" "Group enriched" "Detected in many" 4 "Ciliated cells: 35.6;Ductal cells: 41.1;Glial cells: 62.3;Neuronal cells: 34.3;Renal nephron cells: 47.0" "Cell type enhanced" "Detected in all" "endothelial cell: 162.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 23071851.0" "Group enriched" "Detected in many" "intestine: 15034707.3;lymphoid tissue: 15283018.3" "CAB012643, HPA047193, HPA073217" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 8: Immune cells - Immune response" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 102: Non-specific - Mixed function" 47 "Plasma membrane, Cytosol" "CAB012643: , HPA047193: , HPA073217: " "unprognostic (6.06e-2)" "unprognostic (3.45e-1)" "unprognostic (1.40e-1)" "unprognostic (2.52e-1)" "unprognostic (9.67e-2)" "unprognostic (2.64e-1)" "unprognostic (1.95e-1)" "unprognostic (1.42e-1)" "unprognostic (8.33e-2)" "unprognostic (1.57e-1)" "potential prognostic favorable (1.20e-4)" "unprognostic (4.02e-2)" "unprognostic (2.50e-1)" "unprognostic (6.67e-2)" "unprognostic (1.33e-2)" "unprognostic (4.34e-2)" "unprognostic (7.43e-2)" "unprognostic (2.53e-1)" "unprognostic (3.71e-2)" "unprognostic (1.43e-2)" "unprognostic (7.97e-2)" "unprognostic (4.46e-3)" "unprognostic (2.18e-3)" "unprognostic (2.94e-1)" "unprognostic (1.03e-1)" "unprognostic (1.11e-3)" "unprognostic (1.25e-1)" "unprognostic (2.78e-3)" "unprognostic (4.11e-2)" "unprognostic (1.27e-2)" "unprognostic (1.47e-2)" RILPL2 "FLJ30380, FLJ32372, MGC7036" ENSG00000150977 "Rab interacting lysosomal protein like 2" Q969X0 12 123415039-123436684 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 109.8" "Cell type enriched" "Detected in many" 4 "Neutrophils: 3537.8" "Cell type enriched" "Detected in all" 4 "Neutrophils: 3537.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 73.1" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 858002.0;Smooth muscle cells: 459359.9;T-cells: 1149542.7" "Tissue enriched" "Detected in many" "cerebral cortex: 6833506.6" HPA028958 Approved Supported "Vesicles,Primary cilium,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 8: Immune cells - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 2 Cytosol "Vesicles, Primary cilium" "HPA028958: " "unprognostic (1.92e-1)" "unprognostic (1.37e-3)" "unprognostic (1.72e-1)" "unprognostic (8.22e-3)" "unprognostic (1.45e-2)" "unprognostic (3.59e-1)" "unprognostic (2.79e-2)" "unprognostic (9.93e-3)" "unprognostic (2.08e-1)" "unprognostic (7.17e-2)" "potential prognostic favorable (1.20e-7)" "unprognostic (3.20e-3)" "potential prognostic favorable (2.47e-4)" "unprognostic (2.92e-1)" "unprognostic (1.52e-1)" "unprognostic (1.03e-3)" "unprognostic (2.06e-1)" "unprognostic (9.77e-2)" "unprognostic (2.23e-2)" "unprognostic (1.31e-1)" "unprognostic (9.38e-2)" "unprognostic (4.46e-1)" "unprognostic (2.42e-3)" "unprognostic (2.27e-2)" "unprognostic (1.50e-1)" "unprognostic (1.79e-1)" "unprognostic (1.02e-1)" "unprognostic (2.51e-1)" "unprognostic (1.32e-2)" "unprognostic (5.14e-2)" "potential prognostic favorable (3.01e-4)" RIMBP2 "KIAA0318, MGC15831, PPP1R133, RBP2, RIM-BP2" ENSG00000060709 "RIMS binding protein 2" O15034 12 130396133-130768228 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7;parathyroid gland: 21.3;pituitary gland: 27.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 308.5;Choroid plexus epithelial cells: 453.9;Cone photoreceptor cells: 250.5;Corticotrophs: 205.5;Gonadotrophs: 274.7;Lactotrophs: 857.7;Neuroendocrine cells: 475.4;Pancreatic islet cells: 234.4;Somatotrophs: 1601.4;Thyrotrophs: 526.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 308.5;Ciliated cells: 453.9;Enteroendocrine cells: 475.4;Pituitary endocrine cells: 1601.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Neuroblastoma: 42.6" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Outer root sheath cells, Stomach - Gastric enteroendocrine cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 2790093.3;Microglia and Neuropil: 5677614.5;Neurons: 2622110.2" "Tissue enriched" "Detected in single" 147546 "cerebral cortex: 14754582.1" "HPA041494, HPA044114" Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm "Golgi apparatus, Cytosol" "HPA041494: , HPA044114: " "unprognostic (1.16e-2)" "unprognostic (3.18e-1)" "unprognostic (2.37e-2)" "unprognostic (5.21e-2)" "unprognostic (2.74e-1)" "unprognostic (1.55e-1)" "unprognostic (6.71e-2)" "unprognostic (1.43e-2)" "unprognostic (1.23e-1)" "unprognostic (1.13e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (2.75e-4)" "unprognostic (4.33e-1)" "unprognostic (4.68e-1)" "unprognostic (3.91e-2)" "unprognostic (1.35e-2)" "unprognostic (3.95e-1)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500610-104254430 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 45.5;brain: 41.6;retina: 72.6" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1451.5;Brain inhibitory neurons: 1833.5;Cone photoreceptor cells: 3568.9;Corticotrophs: 2249.2;Gonadotrophs: 2482.8;Lactotrophs: 3054.8;Other brain neurons: 1241.4;Pancreatic islet cells: 1181.8;Retinal bipolar cells: 2072.8;Retinal ganglion cells: 1456.3;Rod photoreceptor cells: 5187.5;Somatotrophs: 2578.3;Thyrotrophs: 3098.9" "Cell type enhanced" "Detected in many" "Neuronal cells: 5187.5;Pancreatic islet cells: 1181.8;Pituitary endocrine cells: 3098.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 17.3" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Pituitary gland - Lactotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 1850363.5;Microglia and Neuropil: 3925238.2" "Tissue enriched" "Detected in single" 61362 "cerebral cortex: 6136220.8" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 34: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 2 "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: " "unprognostic (3.57e-2)" "unprognostic (3.35e-1)" "unprognostic (6.73e-2)" "unprognostic (2.40e-1)" "unprognostic (2.44e-1)" "unprognostic (2.31e-3)" "unprognostic (1.09e-2)" "unprognostic (9.30e-2)" "potential prognostic favorable (5.83e-7)" "unprognostic (1.77e-1)" "unprognostic (3.70e-1)" "unprognostic (2.91e-2)" "unprognostic (2.33e-1)" "unprognostic (8.69e-3)" "unprognostic (2.15e-2)" "unprognostic (2.56e-3)" "unprognostic (1.54e-1)" "unprognostic (6.09e-2)" "unprognostic (3.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.11e-1)" "unprognostic (2.03e-1)" RINL FLJ45909 ENSG00000187994 "Ras and Rab interactor like" Q6ZS11 19 38867830-38878275 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "NK-cells: 12.1;T-cells: 7.9" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 15.7;leukocyte: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 10.4" "Kidney - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Fallopian tube cells: 448551.4;T-cells: 158522.1" "Group enriched" "Detected in some" "fallopian tube: 3077217.5;lymphoid tissue: 900043.3" "HPA042083, HPA042103" Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 14: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 37: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "Nucleoplasm, Vesicles" "HPA042083: , HPA042103: " "unprognostic (4.06e-2)" "unprognostic (1.96e-1)" "unprognostic (2.18e-3)" "unprognostic (2.33e-2)" "unprognostic (6.56e-2)" "unprognostic (3.97e-2)" "unprognostic (5.16e-3)" "unprognostic (2.54e-3)" "potential prognostic favorable (9.70e-4)" "unprognostic (2.26e-2)" "potential prognostic favorable (1.17e-5)" "unprognostic (2.76e-1)" "unprognostic (1.08e-1)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (1.16e-4)" "unprognostic (4.66e-3)" "unprognostic (9.81e-2)" "unprognostic (1.13e-1)" "unprognostic (1.54e-1)" "unprognostic (5.10e-3)" "unprognostic (4.08e-2)" "unprognostic (1.44e-1)" "unprognostic (6.15e-2)" "unprognostic (6.75e-2)" "unprognostic (2.67e-2)" "unprognostic (8.55e-2)" "unprognostic (1.33e-2)" "unprognostic (1.45e-1)" "unprognostic (2.41e-1)" "unprognostic (3.51e-2)" "unprognostic (3.38e-1)" RINT1 "FLJ11785, RINT-1" ENSG00000135249 "RAD50 interactor 1" Q6NUQ1 7 105532169-105567677 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 1637201.9" "Low tissue specificity" "Detected in many" "HPA019875, HPA031646" Approved Approved "Golgi apparatus" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 111 "Golgi apparatus" "HPA019875: , HPA031646: " "unprognostic (4.71e-3)" "unprognostic (1.04e-2)" "unprognostic (7.16e-3)" "unprognostic (5.69e-2)" "unprognostic (9.89e-2)" "unprognostic (3.49e-1)" "unprognostic (1.16e-1)" "unprognostic (2.27e-2)" "unprognostic (2.01e-1)" "unprognostic (6.14e-2)" "potential prognostic favorable (1.43e-6)" "unprognostic (4.53e-1)" "unprognostic (1.06e-1)" "unprognostic (3.96e-2)" "unprognostic (6.03e-3)" "unprognostic (8.82e-2)" "unprognostic (3.18e-2)" "unprognostic (1.88e-1)" "unprognostic (8.12e-2)" "unprognostic (4.00e-2)" "unprognostic (3.06e-1)" "unprognostic (7.54e-2)" "potential prognostic unfavorable (5.81e-4)" "unprognostic (8.74e-2)" "unprognostic (3.37e-2)" "unprognostic (1.90e-1)" "unprognostic (9.12e-3)" "unprognostic (3.64e-2)" "unprognostic (8.61e-2)" "unprognostic (2.51e-2)" "unprognostic (1.62e-1)" RIPK1 "RIP, RIP-1, RIP1" ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063824-3115187 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 309.7;Enterocytes: 345.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "blood vessel: 7543046.0" "CAB010302, HPA015257" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 28: Non-specific - Nuclear processes" "Cluster 65: Non-specific - Cell growth & division" 97 "Plasma membrane, Cytosol" "CAB010302: , HPA015257: " "unprognostic (1.05e-1)" "unprognostic (9.89e-2)" "unprognostic (2.45e-1)" "unprognostic (1.24e-1)" "unprognostic (9.48e-3)" "unprognostic (5.18e-2)" "unprognostic (4.73e-1)" "unprognostic (4.98e-3)" "unprognostic (1.50e-2)" "unprognostic (3.97e-1)" "validated prognostic favorable (2.95e-9)" "validated prognostic favorable (8.86e-4)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (2.51e-2)" "unprognostic (2.80e-1)" "unprognostic (1.54e-1)" "unprognostic (6.68e-3)" "unprognostic (1.61e-1)" "unprognostic (2.71e-1)" "unprognostic (2.32e-1)" "unprognostic (1.66e-1)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (1.40e-1)" "unprognostic (1.50e-1)" "unprognostic (1.34e-1)" "unprognostic (7.84e-3)" "unprognostic (4.74e-2)" RIPK2 "CARD3, CARDIAK, RICK, RIP2" ENSG00000104312 "Receptor interacting serine/threonine kinase 2" O43353 8 89757806-89791064 "Enzymes, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 241.9;Endometrial glandular cells: 399.3;Endometrial luminal cells: 236.2;Megakaryocyte-Erythroid progenitors: 241.7;Monocyte progenitors: 252.1;monocytes: 382.3;Pancreatic duct cells: 302.7" "Cell type enhanced" "Detected in all" "Glandular cells: 399.3;Mononuclear phagocytes: 382.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Microglia and Neuropil: 1066021.3;T-cells: 1307011.4" "Tissue enhanced" "Detected in many" "fallopian tube: 3612181.5" "HPA015273, HPA016499" Approved Enhanced Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 39: Astrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 42 Cytosol "HPA015273: , HPA016499: " "unprognostic (8.07e-2)" "unprognostic (9.20e-2)" "unprognostic (2.21e-1)" "potential prognostic unfavorable (9.06e-4)" "unprognostic (8.95e-2)" "unprognostic (6.98e-2)" "unprognostic (3.23e-2)" "potential prognostic favorable (2.05e-4)" "unprognostic (1.99e-1)" "unprognostic (3.07e-3)" "unprognostic (9.98e-3)" "potential prognostic unfavorable (5.76e-4)" "potential prognostic unfavorable (2.21e-6)" "unprognostic (4.53e-3)" "unprognostic (5.50e-3)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (1.05e-1)" "unprognostic (1.25e-1)" "unprognostic (1.96e-1)" "unprognostic (4.08e-1)" "unprognostic (2.89e-1)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (1.86e-3)" "unprognostic (1.94e-2)" "unprognostic (1.04e-2)" "unprognostic (3.79e-3)" "unprognostic (2.09e-2)" "unprognostic (5.90e-2)" "unprognostic (4.47e-1)" "unprognostic (7.27e-2)" "unprognostic (7.65e-2)" RITA1 "C12orf52, FLJ14827, RITA" ENSG00000139405 "RBPJ interacting and tubulin associated 1" Q96K30 12 113185526-113192368 "Predicted intracellular proteins" "Neurogenesis, Notch signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 57.8;Late spermatids: 45.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 14934 "Fallopian tube cells: 1493440.1" "Not detected" "Not detected" "HPA039094, HPA039095, HPA061531" Supported Supported "Nucleoplasm,Golgi apparatus,Primary cilium,Primary cilium tip,Cytosol" No No "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 93: Hepatocytes - Bile production & excretion" 6 Nucleoplasm "Golgi apparatus, Primary cilium, Primary cilium tip, Cytosol" "HPA039094: , HPA039095: , HPA061531: " "unprognostic (1.41e-1)" "unprognostic (1.87e-1)" "unprognostic (1.66e-1)" "unprognostic (1.42e-1)" "unprognostic (2.48e-2)" "unprognostic (4.58e-2)" "unprognostic (3.11e-2)" "unprognostic (3.26e-1)" "unprognostic (5.11e-2)" "potential prognostic favorable (7.67e-4)" "unprognostic (4.65e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (1.96e-1)" "unprognostic (1.46e-2)" "unprognostic (2.17e-1)" "unprognostic (5.56e-2)" "unprognostic (1.47e-1)" "unprognostic (2.24e-2)" "unprognostic (5.06e-3)" "unprognostic (6.76e-2)" "unprognostic (5.50e-2)" "unprognostic (1.98e-1)" "unprognostic (2.28e-1)" "unprognostic (4.28e-1)" "unprognostic (8.61e-3)" "unprognostic (3.43e-1)" "unprognostic (2.45e-1)" "unprognostic (4.42e-3)" RLBP1 CRALBP ENSG00000140522 "Retinaldehyde binding protein 1" P12271 15 89209869-89221614 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Sensory transduction, Transport, Vision" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "retina: 246.4" "Group enriched" "Detected in some" 90 "Müller glia: 2970.2;Retinal pigment epithelial cells: 2510.9" "Group enriched" "Detected in some" 90 "Glial cells: 2970.2;Pigment cells: 2510.9" "Group enriched" "Detected in some" 9 "astrocyte: 17.1;Bergmann glia: 8.3;choroid plexus epithelial cell: 8.6;oligodendrocyte precursor cell: 6.9" "Group enriched" "Detected in some" 28 "Glioblastoma Multiforme (TCGA): 7.0;Skin Cutaneous Melanoma (TCGA): 15.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "Bile duct cancer: 10.4;colorectal cancer: 3.5;skin cancer: 9.4" "Colon - Enteric glia cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Astrocytes and Neuropil: 169244.1" "Tissue enriched" "Detected in single" 4043 "cerebral cortex: 404300.5" "HPA042051, HPA044083" Enhanced Approved Supported Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 42: Retina - Visual perception" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 Cytosol "Nucleoplasm, Centrosome" "HPA042051: , HPA044083: " "unprognostic (9.81e-2)" "unprognostic (1.39e-2)" "unprognostic (3.31e-2)" RLF "Zn-15L, ZNF292L" ENSG00000117000 "RLF zinc finger" Q13129 1 40161387-40240921 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 708.6" "Cell type enhanced" "Detected in all" "Neutrophils: 708.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2223 "Granulosa cells: 275639.0;Oocytes: 168929.2" "Not detected" "Not detected" "HPA054653, HPA057300" Uncertain Approved Nucleoplasm,Nucleoli Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 8 Nucleoplasm Nucleoli "HPA054653: , HPA057300: " "unprognostic (7.29e-2)" "unprognostic (3.75e-1)" "unprognostic (6.03e-2)" "unprognostic (3.70e-3)" "unprognostic (1.72e-1)" "unprognostic (1.97e-1)" "unprognostic (2.05e-1)" "unprognostic (9.26e-3)" "unprognostic (2.12e-1)" "potential prognostic unfavorable (4.53e-5)" "validated prognostic favorable (1.49e-5)" "validated prognostic favorable (6.19e-5)" "unprognostic (2.38e-2)" "potential prognostic unfavorable (8.88e-5)" "unprognostic (9.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.71e-3)" "unprognostic (2.81e-1)" "unprognostic (8.23e-2)" "unprognostic (1.40e-2)" "unprognostic (7.10e-3)" "unprognostic (4.94e-3)" "unprognostic (8.08e-2)" "unprognostic (5.31e-2)" "unprognostic (1.07e-2)" "unprognostic (1.11e-1)" "unprognostic (5.63e-2)" "unprognostic (3.28e-1)" "unprognostic (3.62e-1)" "unprognostic (3.76e-2)" "unprognostic (3.35e-1)" RMDN2 "FAM82A, FAM82A1, FLJ32954, RMD2" ENSG00000115841 "Regulator of microtubule dynamics 2" Q96LZ7 2 37923187-38067142 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 40.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 327.4;Early spermatids: 255.0;Late primary spermatocytes: 212.1;Late spermatids: 240.4" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 327.4;Spermatogenic cell types: 255.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 77786406.8" "Tissue enriched" "Detected in many" "liver: 23099396.6" "HPA034705, HPA034706" Enhanced Supported "Golgi apparatus,Mitotic spindle,Cytosol" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 19 "Mitotic spindle, Cytosol" "Golgi apparatus" "HPA034705: , HPA034706: " "unprognostic (1.82e-1)" "unprognostic (3.03e-1)" "unprognostic (1.68e-1)" "unprognostic (1.64e-1)" "unprognostic (1.44e-1)" "unprognostic (3.31e-3)" "unprognostic (2.08e-2)" "unprognostic (2.32e-1)" "unprognostic (9.06e-2)" "potential prognostic favorable (1.98e-7)" "unprognostic (2.70e-3)" "potential prognostic favorable (2.51e-4)" "unprognostic (1.23e-2)" "potential prognostic favorable (9.16e-4)" "unprognostic (4.30e-2)" "unprognostic (2.38e-2)" "unprognostic (1.31e-1)" "unprognostic (5.43e-2)" "unprognostic (1.60e-2)" "unprognostic (1.98e-2)" "unprognostic (3.03e-1)" "unprognostic (4.84e-2)" "unprognostic (8.15e-2)" "unprognostic (2.45e-3)" "unprognostic (2.45e-2)" "unprognostic (1.21e-2)" "unprognostic (8.25e-2)" "unprognostic (3.47e-2)" "unprognostic (3.14e-2)" RMDN3 "FAM82A2, FAM82C, FLJ10579, PTPIP51, RMD3" ENSG00000137824 "Regulator of microtubule dynamics 3" Q96TC7 15 40735884-40755851 "Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "cerebral cortex: 15092492.8" "HPA009975, HPA074840" Supported Enhanced "Cytokinetic bridge,Mitochondria" Yes No 22000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 53 Mitochondria "Cytokinetic bridge" "HPA009975: , HPA074840: " "unprognostic (4.23e-2)" "unprognostic (3.21e-2)" "unprognostic (9.02e-2)" "unprognostic (7.21e-2)" "unprognostic (1.34e-1)" "unprognostic (2.67e-2)" "unprognostic (1.29e-1)" "unprognostic (1.66e-3)" "unprognostic (2.95e-1)" "potential prognostic favorable (2.25e-10)" "unprognostic (1.60e-3)" "unprognostic (1.17e-1)" "unprognostic (7.85e-2)" "unprognostic (1.03e-1)" "unprognostic (2.51e-1)" "unprognostic (4.09e-2)" "unprognostic (8.01e-2)" "unprognostic (9.33e-2)" "unprognostic (3.11e-1)" "unprognostic (1.16e-3)" "unprognostic (8.79e-2)" "unprognostic (8.81e-3)" "unprognostic (4.81e-1)" "unprognostic (3.02e-2)" "unprognostic (6.77e-2)" "unprognostic (3.71e-2)" "unprognostic (3.58e-1)" "unprognostic (6.95e-2)" "unprognostic (9.02e-2)" RNASEH2A "AGS4, RNASEHI, RNHIA, RNHL" ENSG00000104889 "Ribonuclease H2 subunit A" O75792 19 12806584-12813640 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 7.1;Differentiating spermatogonia: 7.1;Enteric stem cells: 8.7;Enteric transient amplifying cells: 16.7;Erythrocyte progenitors: 8.7;Extravillous trophoblasts: 11.6;Gastric progenitor cells: 7.7;Megakaryocyte progenitors: 7.2;Megakaryocytes: 12.4;Migrating cytotrophoblasts: 9.3;Paneth cells: 11.6" "Cell type enhanced" "Detected in many" "Megakaryocytes: 12.4;Proliferating cells: 16.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 9002953.9" "Tissue enhanced" "Detected in many" "bone marrow: 9191994.2" HPA042692 Enhanced Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 30: White matter - Myelination" "Cluster 23: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 16 Nucleoplasm Cytosol "HPA042692: " "unprognostic (2.14e-3)" "unprognostic (2.47e-2)" "unprognostic (2.96e-1)" "potential prognostic favorable (3.94e-4)" "unprognostic (2.21e-3)" "unprognostic (1.85e-2)" "unprognostic (1.31e-1)" "unprognostic (1.56e-1)" "unprognostic (1.87e-1)" "unprognostic (5.20e-3)" "unprognostic (4.11e-2)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (2.17e-5)" "validated prognostic unfavorable (3.49e-5)" "validated prognostic unfavorable (2.52e-7)" "unprognostic (2.23e-3)" "potential prognostic unfavorable (8.73e-4)" "unprognostic (3.65e-3)" "unprognostic (2.11e-2)" "potential prognostic favorable (2.17e-4)" "unprognostic (3.57e-1)" "unprognostic (4.80e-3)" "unprognostic (9.59e-2)" "unprognostic (3.33e-2)" "unprognostic (2.20e-2)" "unprognostic (2.32e-2)" "unprognostic (3.29e-1)" "unprognostic (2.44e-2)" "unprognostic (8.06e-2)" "unprognostic (1.06e-1)" "unprognostic (1.49e-1)" RNF10 "KIAA0262, RIE2" ENSG00000022840 "Ring finger protein 10" Q8N5U6 12 120533480-120577588 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 459.7;Neutrophils: 596.2" "Cell type enhanced" "Detected in all" "Neutrophils: 596.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 173 "Neurons: 17258.3" "Not detected" "Not detected" HPA052643 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 52: Non-specific - Cellular respiration" "Cluster 7: Non-specific - Ribosome" "Cluster 38: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 39 Nucleoplasm Mitochondria "HPA052643: " "unprognostic (5.65e-2)" "unprognostic (5.32e-2)" "unprognostic (2.47e-1)" "unprognostic (6.90e-3)" "unprognostic (1.27e-1)" "unprognostic (1.40e-2)" "unprognostic (2.20e-1)" "unprognostic (1.34e-1)" "unprognostic (2.14e-3)" "unprognostic (3.57e-2)" "unprognostic (6.99e-3)" "unprognostic (8.46e-3)" "unprognostic (8.33e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.01e-3)" "unprognostic (1.28e-3)" "unprognostic (2.04e-1)" "unprognostic (1.32e-1)" "unprognostic (2.68e-1)" "unprognostic (5.59e-1)" "unprognostic (3.31e-2)" "unprognostic (2.32e-1)" "unprognostic (3.82e-2)" "unprognostic (2.39e-1)" "unprognostic (2.60e-2)" "unprognostic (1.21e-1)" "unprognostic (6.48e-2)" "unprognostic (2.59e-1)" "unprognostic (9.94e-2)" "unprognostic (1.39e-1)" "unprognostic (1.14e-1)" RNF144A "hUIP4, KIAA0161, RNF144, UBCE7IP4" ENSG00000151692 "Ring finger protein 144A" P50876 2 6917412-7068286 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 307.9;Cone photoreceptor cells: 681.1;Gonadotrophs: 358.4;Oligodendrocyte progenitor cells: 354.6;Oligodendrocytes: 493.7;Rod photoreceptor cells: 489.6;Somatotrophs: 245.8;Thyrotrophs: 232.6" "Cell type enhanced" "Detected in many" "Glial cells: 493.7;Neuronal cells: 681.1;Pituitary endocrine cells: 358.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 6.1" "Group enriched" "Detected in many" 8 "granulocytes: 6.1;T-cells: 2.4" "Cancer enhanced" "Detected in many" "Neuroblastoma: 27.7;skin cancer: 30.3" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA049939 Approved Supported Vesicles NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 27: Cerebellum - Synaptic function" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 49: HMC-1 - Innate immune response" "Cluster 79: Photoreceptor cells - Phototransduction" 26 Vesicles "HPA049939: " "unprognostic (1.33e-2)" "unprognostic (4.02e-1)" "unprognostic (6.37e-2)" "unprognostic (6.81e-2)" "unprognostic (2.04e-1)" "unprognostic (1.88e-1)" "unprognostic (4.22e-2)" "unprognostic (4.64e-3)" "unprognostic (6.34e-3)" "potential prognostic unfavorable (2.87e-5)" "unprognostic (9.85e-3)" "unprognostic (1.05e-2)" "unprognostic (1.18e-3)" "potential prognostic unfavorable (1.73e-4)" "unprognostic (9.77e-3)" "unprognostic (4.94e-2)" "unprognostic (3.71e-2)" "unprognostic (5.92e-2)" "unprognostic (2.50e-1)" "unprognostic (9.94e-2)" "unprognostic (7.49e-2)" "unprognostic (4.95e-2)" "unprognostic (6.77e-2)" "unprognostic (1.90e-1)" "unprognostic (9.24e-3)" "unprognostic (1.97e-2)" "unprognostic (1.47e-2)" "potential prognostic unfavorable (4.20e-6)" "unprognostic (7.18e-2)" "unprognostic (6.99e-2)" "unprognostic (7.40e-2)" RNF144B "bA528A10.3, IBRDC2, P53RFP" ENSG00000137393 "Ring finger protein 144B" Q7Z419 6 18387350-18468870 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 53.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 705.4;cDC: 613.5;Epididymal basal cells: 498.1;Kupffer cells: 442.8;Macrophages: 522.3;monocytes: 1203.4;Neutrophil progenitors: 507.8;Neutrophils: 3933.9;Suprabasal keratinocytes: 1427.4" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 1203.4;Neutrophils: 3933.9;Suprabasal cells: 1427.4" "Cell type enriched" "Detected in many" 5 "endothelial cell: 655.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 72.3" "Group enriched" "Detected in many" 9 "dendritic cells: 18.4;granulocytes: 36.8;monocytes: 72.3" "Cancer enhanced" "Detected in many" "lymphoma: 28.9" "Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB046013, HPA054127, HPA072469" Uncertain Approved Nucleoli,Mitochondria NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 10 Nucleoli Mitochondria "CAB046013: , HPA054127: , HPA072469: " "unprognostic (1.29e-1)" "unprognostic (9.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.24e-1)" "unprognostic (3.38e-1)" "unprognostic (3.75e-2)" "unprognostic (6.26e-2)" "unprognostic (2.95e-1)" "unprognostic (6.43e-3)" "unprognostic (9.91e-2)" "potential prognostic favorable (2.33e-4)" "unprognostic (3.49e-2)" "unprognostic (1.42e-1)" "unprognostic (3.17e-1)" "potential prognostic favorable (4.09e-5)" "unprognostic (1.90e-2)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "unprognostic (5.53e-1)" "unprognostic (1.89e-2)" "unprognostic (1.14e-1)" "unprognostic (3.21e-2)" "unprognostic (1.72e-2)" "unprognostic (1.83e-1)" "unprognostic (6.93e-2)" "unprognostic (6.85e-2)" "unprognostic (4.73e-2)" "unprognostic (8.17e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-2)" "unprognostic (7.82e-3)" RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266726-127288567 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 168.4;Neutrophils: 173.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 40403.5;Neurons: 66249.6" "Tissue enhanced" "Detected in some" "heart muscle: 23379.0" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 35: Neutrophils - Protein binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 41 "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: , HPA027209: " "unprognostic (1.10e-1)" "unprognostic (4.18e-3)" "unprognostic (3.44e-2)" "unprognostic (7.48e-3)" "unprognostic (5.52e-2)" "unprognostic (7.11e-2)" "unprognostic (5.67e-2)" "unprognostic (8.36e-2)" "unprognostic (2.68e-2)" "unprognostic (4.38e-2)" "potential prognostic favorable (1.26e-6)" "unprognostic (7.72e-3)" "unprognostic (2.07e-1)" "unprognostic (5.89e-3)" "unprognostic (9.05e-2)" "unprognostic (2.32e-2)" "unprognostic (3.71e-1)" "unprognostic (9.35e-2)" "unprognostic (2.48e-1)" "unprognostic (2.00e-2)" "unprognostic (4.47e-2)" "unprognostic (1.89e-3)" "unprognostic (1.06e-1)" "unprognostic (1.84e-1)" "unprognostic (1.16e-1)" "unprognostic (2.02e-2)" "unprognostic (1.52e-1)" "unprognostic (2.25e-2)" "unprognostic (7.60e-2)" "unprognostic (2.19e-2)" "unprognostic (3.02e-1)" RNF148 MGC35222 ENSG00000235631 "Ring finger protein 148" Q8N7C7 7 122701668-122702922 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "testis: 48.3" "Cell type enhanced" "Detected in some" "Early spermatids: 8.7;Late primary spermatocytes: 3.9;Late spermatids: 2.0" "Cell type enriched" "Detected in single" 53 "Spermatogenic cell types: 8.7" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in all" "cerebellum: 22.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 320 "skin: 31991.3" HPA045587 Approved Cytosol NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Cytosol "HPA045587: " "unprognostic (2.61e-1)" "unprognostic (1.52e-1)" "unprognostic (4.46e-1)" "unprognostic (1.30e-1)" RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 86.0;lymphoid tissue: 98.5" "Cell type enhanced" "Detected in many" "cDC: 49.6;Hofbauer cells: 46.4;Macrophages: 45.4;Microglia: 65.4;Monocyte progenitors: 48.5;monocytes: 67.9;Neutrophil progenitors: 70.5;Neutrophils: 153.0;NK-cells: 82.2;T-cells: 60.4" "Cell type enhanced" "Detected in many" "Neutrophils: 153.0;NK-cells: 82.2" "Group enriched" "Detected in all" 5 "central nervous system macrophage: 79.8;leukocyte: 84.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - T-cells, Breast - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 186 "B-cells: 26063.7;Macrophages: 11204.4" "Not detected" "Not detected" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 18 Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: " "unprognostic (2.92e-1)" "unprognostic (2.50e-2)" "unprognostic (6.93e-2)" "unprognostic (2.92e-1)" "unprognostic (6.87e-3)" "unprognostic (2.85e-1)" "unprognostic (1.10e-1)" "unprognostic (3.19e-2)" "unprognostic (1.64e-2)" "unprognostic (7.79e-2)" "potential prognostic unfavorable (1.32e-4)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (3.99e-2)" "unprognostic (4.62e-3)" "unprognostic (6.96e-3)" "unprognostic (4.52e-1)" "unprognostic (7.28e-2)" "unprognostic (4.20e-1)" "unprognostic (7.49e-2)" "unprognostic (3.68e-3)" "potential prognostic favorable (1.72e-4)" "unprognostic (4.06e-2)" "unprognostic (1.79e-1)" "unprognostic (1.34e-1)" "unprognostic (7.21e-2)" "unprognostic (1.44e-1)" "unprognostic (3.89e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (1.18e-2)" RNF167 DKFZP566H073 ENSG00000108523 "Ring finger protein 167" Q9H6Y7 17 4940008-4945222 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 213.6;Extravillous trophoblasts: 182.3;Oocytes: 285.5" "Cell type enhanced" "Detected in all" "Oocytes: 285.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 82137.4;Keratinocytes: 153625.7;Neurons: 159569.8;Oocytes: 45111.5" "Tissue enhanced" "Detected in many" "lymphoid tissue: 3517063.8" HPA049810 Approved Approved "Vesicles,Mitotic spindle,Centriolar satellite,Cytosol" Yes NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 23 "Vesicles, Cytosol" "Mitotic spindle, Centriolar satellite" "HPA049810: " "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.24e-3)" "unprognostic (3.84e-2)" "unprognostic (4.06e-2)" "unprognostic (1.51e-1)" "unprognostic (2.21e-2)" "unprognostic (4.95e-2)" "unprognostic (4.14e-2)" "unprognostic (8.13e-2)" "unprognostic (1.37e-2)" "unprognostic (1.28e-2)" "potential prognostic favorable (2.50e-5)" "unprognostic (6.14e-2)" "unprognostic (2.56e-1)" "unprognostic (8.25e-2)" "unprognostic (6.85e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (2.85e-1)" "unprognostic (3.76e-3)" "unprognostic (3.66e-2)" "potential prognostic favorable (3.05e-6)" "unprognostic (3.51e-1)" "unprognostic (1.13e-1)" "unprognostic (1.39e-2)" "unprognostic (7.08e-2)" "unprognostic (9.04e-2)" "unprognostic (2.10e-1)" "unprognostic (3.59e-1)" "unprognostic (2.30e-1)" "unprognostic (2.99e-1)" RNF169 KIAA1991 ENSG00000166439 "Ring finger protein 169" Q8NCN4 11 74748849-74842413 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 380.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 380.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 685105.2;Neurons: 571969.8" "Group enriched" "Detected in some" 1869 "lymphoid tissue: 218236.4;ovary: 155526.7" "HPA038505, HPA046138, HPA047952" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 16 "Nucleoplasm, Nuclear bodies" "Nucleoli, Nucleoli rim, Cytosol" "HPA038505: , HPA046138: , HPA047952: " "unprognostic (3.14e-2)" "unprognostic (1.21e-1)" "unprognostic (1.33e-3)" "unprognostic (2.42e-2)" "unprognostic (2.27e-1)" "unprognostic (2.77e-3)" "unprognostic (8.71e-2)" "unprognostic (6.28e-2)" "unprognostic (4.53e-2)" "potential prognostic unfavorable (5.05e-4)" "potential prognostic favorable (3.17e-5)" "unprognostic (4.09e-3)" "unprognostic (1.65e-1)" "unprognostic (2.75e-2)" "unprognostic (3.46e-1)" "unprognostic (2.29e-1)" "unprognostic (4.72e-2)" "unprognostic (3.62e-2)" "unprognostic (3.04e-2)" "unprognostic (5.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.44e-3)" "unprognostic (4.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.93e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (1.95e-1)" "unprognostic (3.34e-1)" "unprognostic (1.57e-1)" "unprognostic (1.45e-2)" "unprognostic (4.03e-3)" RNF187 "RACO-1, RACO1" ENSG00000168159 "Ring finger protein 187" Q5TA31 1 228487382-228499899 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 16.2;Brain excitatory neurons: 33.1;Brain inhibitory neurons: 29.7;Ependymal cells: 22.9;Loop of henle epithelial cells: 10.3;Oligodendrocyte progenitor cells: 15.7;Oligodendrocytes: 21.5;Other brain neurons: 44.5;Papillary tip epithelial cells: 12.8;Podocytes: 17.3;Renal collecting duct principal cells: 10.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 22.9;Glial cells: 21.5;Neuronal cells: 44.5;Renal nephron cells: 17.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 663 "Microglia and Neuropil: 78205.4;Neurons: 39883.4;Oocytes: 46272.0;Proximal tubules: 100721.7" "Not detected" "Not detected" HPA030098 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 98: Neurons - Neurotransmission & signaling" 12 "Nucleoplasm, Cytosol" "HPA030098: " "unprognostic (1.32e-1)" "unprognostic (1.97e-3)" "unprognostic (5.40e-2)" "unprognostic (4.26e-3)" "unprognostic (1.44e-1)" "unprognostic (5.28e-3)" "unprognostic (1.56e-1)" "unprognostic (4.72e-1)" "unprognostic (6.79e-2)" "unprognostic (2.90e-2)" "potential prognostic favorable (2.15e-4)" "unprognostic (1.40e-1)" "unprognostic (5.89e-2)" "unprognostic (6.77e-2)" "unprognostic (5.91e-3)" "unprognostic (1.56e-1)" "unprognostic (1.84e-3)" "unprognostic (1.79e-1)" "unprognostic (1.16e-1)" "unprognostic (2.04e-2)" "unprognostic (4.96e-2)" "unprognostic (4.71e-2)" "unprognostic (1.68e-1)" "unprognostic (1.63e-2)" "unprognostic (6.19e-2)" "unprognostic (3.02e-1)" "unprognostic (3.20e-1)" "unprognostic (2.43e-1)" "unprognostic (4.15e-1)" "unprognostic (7.43e-3)" "unprognostic (3.20e-2)" RNF215 ENSG00000099999 "Ring finger protein 215" Q9Y6U7 22 30368811-30421771 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 66.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 242 "Fallopian tube cells: 24176.0" "Not detected" "Not detected" "HPA029427, HPA056498" Approved Approved Nucleoli,Microtubules NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 15: Kidney cancer - Membrane components" "Cluster 11: Muller glia cells - Retinal homeostasis" 1 Microtubules Nucleoli "HPA029427: , HPA056498: " "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (2.40e-1)" "unprognostic (3.18e-2)" "unprognostic (5.08e-2)" "unprognostic (3.26e-1)" "unprognostic (2.25e-1)" "unprognostic (1.36e-1)" "unprognostic (1.24e-1)" "unprognostic (6.32e-2)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.24e-1)" "unprognostic (1.30e-1)" "unprognostic (4.70e-2)" "unprognostic (1.81e-2)" "unprognostic (8.02e-2)" "unprognostic (3.24e-1)" "unprognostic (2.95e-1)" "unprognostic (8.69e-2)" "unprognostic (1.26e-1)" "unprognostic (7.57e-2)" "unprognostic (2.54e-1)" "unprognostic (3.26e-2)" "unprognostic (2.78e-3)" "unprognostic (5.70e-2)" "unprognostic (1.29e-2)" "unprognostic (2.88e-1)" "unprognostic (2.79e-1)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.76e-1)" RNF25 "AO7, FLJ13906" ENSG00000163481 "Ring finger protein 25" Q96BH1 2 218663892-218672002 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "cerebral cortex: 781210.5;intestine: 258682.7;lymphoid tissue: 220886.7;Stomach: 520256.3" "HPA036420, HPA036421" Uncertain Approved "Nucleoplasm,Actin filaments,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 32 Cytosol "Nucleoplasm, Actin filaments" "HPA036420: , HPA036421: " "unprognostic (6.72e-3)" "unprognostic (2.06e-1)" "unprognostic (4.10e-2)" "potential prognostic favorable (4.59e-4)" "unprognostic (1.67e-1)" "unprognostic (7.37e-2)" "unprognostic (1.98e-1)" "unprognostic (2.21e-2)" "unprognostic (7.57e-2)" "unprognostic (2.89e-1)" "unprognostic (2.70e-2)" "unprognostic (3.45e-2)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (2.31e-2)" "unprognostic (1.36e-2)" "unprognostic (7.68e-2)" "unprognostic (2.69e-1)" "unprognostic (1.70e-1)" "unprognostic (1.36e-1)" "unprognostic (1.66e-2)" "unprognostic (1.39e-2)" "unprognostic (1.09e-1)" "unprognostic (5.77e-2)" "unprognostic (4.54e-1)" "unprognostic (1.67e-1)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (5.93e-3)" "unprognostic (3.09e-1)" "unprognostic (8.41e-2)" RNF4 "RES4-26, SLX5, SNURF" ENSG00000063978 "Ring finger protein 4" P78317 4 2462220-2515857 "Enzymes, Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, DNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 15999 "intestine: 1599924.5" "HPA022047, HPA049356" Approved Supported "Nucleoplasm,Nuclear bodies,Microtubule ends" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 38: Sub-cortical - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 165 "Nucleoplasm, Nuclear bodies" "Microtubule ends" "HPA022047: , HPA049356: " "unprognostic (1.36e-2)" "unprognostic (1.25e-2)" "unprognostic (1.04e-1)" "unprognostic (3.36e-2)" "unprognostic (8.09e-3)" "unprognostic (6.68e-2)" "unprognostic (1.90e-1)" "unprognostic (1.89e-2)" "unprognostic (4.86e-2)" "unprognostic (1.23e-3)" "potential prognostic favorable (8.23e-5)" "unprognostic (3.79e-3)" "unprognostic (6.26e-2)" "unprognostic (2.94e-3)" "unprognostic (7.43e-3)" "unprognostic (2.09e-3)" "potential prognostic unfavorable (7.00e-4)" "unprognostic (7.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.32e-1)" "unprognostic (7.13e-3)" "unprognostic (2.43e-1)" "unprognostic (1.58e-1)" "unprognostic (6.50e-2)" "unprognostic (4.75e-2)" "unprognostic (3.57e-1)" "unprognostic (1.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.94e-1)" "unprognostic (2.05e-2)" "unprognostic (2.08e-1)" RNF41 "NRDP1, SBBI03" ENSG00000181852 "Ring finger protein 41" Q9H4P4 12 56202179-56221933 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Autophagy, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 103.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Macrophages: 1505665.6;Microglia and Neuropil: 527684.7;Neurons: 618393.0" "Tissue enriched" "Detected in single" 271 "cerebral cortex: 27134.6" HPA016812 Approved Approved "Nucleoplasm,Nuclear bodies,Midbody ring" Yes NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 67 "Nucleoplasm, Nuclear bodies" "Midbody ring" "HPA016812: " "unprognostic (1.59e-1)" "unprognostic (1.43e-2)" "unprognostic (7.78e-3)" "unprognostic (5.18e-2)" "unprognostic (2.62e-2)" "unprognostic (1.77e-1)" "unprognostic (3.43e-1)" "unprognostic (1.22e-3)" "unprognostic (2.74e-2)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.36e-8)" "unprognostic (1.36e-3)" "unprognostic (3.87e-1)" "unprognostic (9.36e-3)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (2.22e-1)" "unprognostic (9.67e-2)" "unprognostic (1.33e-1)" "unprognostic (5.95e-2)" "unprognostic (9.89e-2)" "unprognostic (1.68e-2)" "unprognostic (2.26e-1)" "unprognostic (2.38e-1)" "unprognostic (1.14e-1)" "unprognostic (3.03e-2)" "unprognostic (2.30e-1)" "unprognostic (7.20e-3)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (1.05e-1)" "unprognostic (8.30e-2)" RNFT2 "FLJ14627, TMEM118" ENSG00000135119 "Ring finger protein, transmembrane 2" Q96EX2 12 116738178-116853631 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 10.3;choroid plexus: 4.7;pituitary gland: 4.9;retina: 4.6;testis: 6.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 42.5;Corticotrophs: 41.9;Early spermatids: 56.7;Gonadotrophs: 46.2;Lactotrophs: 48.1;Late spermatids: 98.4;Retinal amacrine cells: 50.6;Retinal bipolar cells: 50.4;Retinal ganglion cells: 46.4;Rod photoreceptor cells: 56.2;Somatotrophs: 44.6;Thyrotrophs: 66.6" "Cell type enhanced" "Detected in many" "Neuronal cells: 56.2;Pituitary endocrine cells: 66.6;Spermatogenic cell types: 98.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 1079295.5" "Not detected" "Not detected" HPA064161 Enhanced Approved Nucleoplasm,Cytosol No No "Cluster 34: B-cells - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 24: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" Nucleoplasm Cytosol "HPA064161: " "unprognostic (2.01e-2)" "unprognostic (2.79e-3)" "unprognostic (3.98e-1)" "unprognostic (1.29e-1)" "unprognostic (1.53e-2)" "unprognostic (2.72e-3)" "unprognostic (1.86e-1)" "unprognostic (3.55e-3)" "unprognostic (1.17e-2)" "unprognostic (6.66e-3)" "unprognostic (1.38e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-1)" "unprognostic (1.60e-2)" "unprognostic (2.49e-1)" "unprognostic (1.45e-1)" "unprognostic (1.66e-1)" "unprognostic (7.27e-3)" "unprognostic (1.06e-1)" "unprognostic (2.34e-2)" "unprognostic (9.24e-3)" "unprognostic (2.51e-1)" "unprognostic (2.93e-1)" "unprognostic (1.54e-1)" "potential prognostic favorable (7.35e-4)" RNPEP APB ENSG00000176393 "Arginyl aminopeptidase" Q9H4A4 1 201982372-202006147 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enterocytes: 207.7;Esophageal apical cells: 200.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 19.8;granulocytes: 23.2;monocytes: 30.0" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Prostate - Prostate basal glandular cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA036074, HPA036075, HPA061487" Approved Approved "Golgi apparatus,Principal piece,End piece" "Secreted - unknown location" Enzyme NA NA 6400000 "Cluster 25: Non-specific - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 "Golgi apparatus" "Principal piece, End piece" "HPA036074: , HPA036075: , HPA061487: " "unprognostic (7.10e-2)" "unprognostic (1.11e-2)" "unprognostic (3.09e-1)" "unprognostic (1.08e-3)" "unprognostic (2.17e-2)" "unprognostic (4.32e-2)" "unprognostic (3.58e-1)" "unprognostic (2.27e-2)" "unprognostic (3.21e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (2.26e-6)" "unprognostic (7.34e-2)" "unprognostic (6.20e-2)" "unprognostic (2.18e-1)" "unprognostic (1.27e-2)" "unprognostic (7.07e-3)" "unprognostic (1.62e-1)" "unprognostic (5.91e-3)" "unprognostic (5.90e-2)" "unprognostic (1.02e-2)" "unprognostic (2.92e-1)" "unprognostic (3.00e-2)" "unprognostic (8.67e-2)" "unprognostic (1.66e-1)" "unprognostic (1.90e-2)" "unprognostic (2.78e-2)" "unprognostic (2.34e-3)" "unprognostic (1.27e-1)" "unprognostic (8.69e-2)" "unprognostic (1.34e-2)" "unprognostic (2.37e-1)" RO60 "SSA2, TROVE2" ENSG00000116747 "Ro60, Y RNA binding protein" P10155 1 193059454-193091777 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 462.6" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 462.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA002835 Uncertain Approved "Nucleoplasm,Nuclear bodies,Primary cilium,Cytosol" NA NA 65000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 16 "Primary cilium, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA002835: " "unprognostic (3.65e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (1.62e-1)" "unprognostic (1.18e-1)" "unprognostic (4.06e-2)" "unprognostic (4.45e-1)" "unprognostic (2.31e-1)" "unprognostic (7.24e-3)" "potential prognostic favorable (4.27e-5)" "unprognostic (2.68e-2)" "unprognostic (7.72e-2)" "unprognostic (1.00e-2)" "unprognostic (1.36e-1)" "unprognostic (9.40e-2)" "unprognostic (1.63e-1)" "unprognostic (3.17e-1)" "unprognostic (2.61e-1)" "potential prognostic unfavorable (3.81e-5)" "unprognostic (1.50e-2)" "unprognostic (1.94e-1)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.39e-1)" "unprognostic (5.70e-2)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.11e-1)" ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 1648.7;Brain excitatory neurons: 1017.0;Brain inhibitory neurons: 2256.4;Lactotrophs: 5760.6;Other brain neurons: 1644.2;Prostatic club cells: 945.3;Thyrotrophs: 1197.6" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 1648.7;Neuronal cells: 2256.4;Pituitary endocrine cells: 5760.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Heart muscle - Fibroblasts, Prostate - Urothelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 463915.0;Keratinocytes: 326575.0" "Group enriched" "Detected in some" "cerebral cortex: 4533483.7;fallopian tube: 2006928.6;lymphoid tissue: 3607163.1;ovary: 3793152.1" "CAB013524, HPA052968, HPA074461" Uncertain Supported "Plasma membrane,Primary cilium" NA NA 7300000 "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 6 "Plasma membrane" "Primary cilium" "CAB013524: , HPA052968: , HPA074461: " "unprognostic (2.83e-1)" "unprognostic (4.14e-1)" "unprognostic (4.24e-2)" "unprognostic (1.22e-2)" "unprognostic (1.41e-1)" "unprognostic (2.65e-2)" "unprognostic (4.46e-1)" "unprognostic (2.89e-1)" "potential prognostic favorable (1.50e-4)" "unprognostic (5.29e-2)" "potential prognostic favorable (5.71e-5)" "unprognostic (2.26e-1)" "unprognostic (1.57e-1)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (9.62e-2)" "unprognostic (3.60e-1)" "unprognostic (1.59e-1)" "unprognostic (9.87e-2)" "unprognostic (2.94e-1)" "unprognostic (1.36e-1)" "unprognostic (1.79e-1)" "unprognostic (8.14e-2)" "unprognostic (1.60e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-2)" "potential prognostic favorable (7.36e-4)" "unprognostic (8.65e-2)" "unprognostic (1.48e-2)" "unprognostic (1.89e-1)" "unprognostic (1.95e-2)" "unprognostic (2.36e-1)" ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.4;ovary: 13.1" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 1735.5;Brain inhibitory neurons: 3594.0;Ependymal cells: 1137.8;Fibro-adipogenic progenitors: 997.8;Lactotrophs: 1602.3;Other brain neurons: 1567.7;Podocytes: 917.5;Retinal bipolar cells: 2300.0;Retinal ganglion cells: 3970.9;Sertoli cells: 758.3;Somatotrophs: 1964.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 1137.8;Fibro-adipogenic progenitors: 997.8;Neuronal cells: 3970.9;Pituitary endocrine cells: 1964.4" "Cell type enhanced" "Detected in all" "lower rhombic lip: 8990.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 20.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal medulla cells, Kidney - Podocytes, Lung - Fibroblasts_1, Pancreas - Beta cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 874869.6;Glomeruli: 629118.0;Microglia and Neuropil: 1123285.6;Neurons: 290859.0" "Group enriched" "Detected in some" "cerebral cortex: 5828498.5;fallopian tube: 9931881.1;intestine: 4424658.7;ovary: 3527135.0" "HPA013371, HPA014209" Approved Approved "Vesicles,Plasma membrane" NA NA 810000 "Cluster 65: Brain - Transcription" "Cluster 24: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 1 "Vesicles, Plasma membrane" "HPA013371: , HPA014209: " "unprognostic (3.59e-2)" "unprognostic (3.01e-3)" "unprognostic (3.52e-1)" "unprognostic (2.95e-2)" "unprognostic (9.60e-3)" "unprognostic (1.30e-1)" "unprognostic (7.55e-3)" "unprognostic (4.31e-2)" "unprognostic (2.35e-2)" "unprognostic (3.19e-1)" "potential prognostic favorable (1.86e-5)" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (6.81e-2)" "unprognostic (7.56e-2)" "unprognostic (3.27e-2)" "unprognostic (2.80e-1)" "unprognostic (3.75e-1)" "unprognostic (2.31e-1)" "unprognostic (8.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.99e-1)" "unprognostic (2.19e-2)" "unprognostic (1.52e-1)" "unprognostic (9.47e-2)" "unprognostic (4.46e-1)" ROM1 "ROM, TSPAN23" ENSG00000149489 "Retinal outer segment membrane protein 1" Q03395 11 62611722-62615116 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 16 "retina: 1101.4" "Cell type enriched" "Detected in many" 8 "Rod photoreceptor cells: 1647.4" "Cell type enriched" "Detected in many" 17 "Neuronal cells: 1647.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 51.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.7" "Group enriched" "Detected in many" 4 "NK-cells: 2.7;T-cells: 1.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Keratinocytes: 6567814.8" "Not detected" "Not detected" "HPA028910, HPA073279" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 19: Astrocytes - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Plasma membrane, Cytosol" Nucleoplasm "HPA028910: , HPA073279: " "unprognostic (1.34e-1)" "unprognostic (3.25e-2)" "potential prognostic favorable (4.15e-4)" "unprognostic (8.66e-2)" "unprognostic (2.49e-2)" "unprognostic (1.37e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-2)" "unprognostic (3.64e-1)" "unprognostic (2.51e-2)" "potential prognostic unfavorable (1.54e-4)" "unprognostic (1.03e-1)" "unprognostic (6.58e-3)" "unprognostic (2.84e-1)" "unprognostic (1.99e-2)" "potential prognostic favorable (8.75e-4)" "unprognostic (4.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-1)" "unprognostic (3.17e-1)" "unprognostic (3.19e-2)" "unprognostic (3.20e-2)" "unprognostic (5.46e-2)" "unprognostic (5.50e-2)" "unprognostic (4.31e-2)" "unprognostic (6.46e-2)" "unprognostic (2.12e-1)" "unprognostic (2.74e-1)" "unprognostic (2.54e-1)" "unprognostic (9.48e-2)" ROPN1L "ASP, FLJ25776, RSPH11" ENSG00000145491 "Rhophilin associated tail protein 1 like" Q96C74 5 10441524-10472029 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 304.2" "Group enriched" "Detected in many" 5 "Early spermatids: 2979.4;Late primary spermatocytes: 3415.0;Late spermatids: 4288.1" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 4288.1" "Cell type enriched" "Detected in many" 13 "ependymal cell: 359.6" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 13.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 45.2;eosinophil: 55.2;neutrophil: 105.7" "Lineage enriched" "Detected in many" 18 "granulocytes: 105.7" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 166685 "Fallopian tube cells: 16668522.0" "Tissue enriched" "Detected in single" 245841 "fallopian tube: 24584058.2" "HPA039193, HPA041830" Enhanced Supported "Nucleoplasm,Vesicles,Primary cilium transition zone,Mid piece,Principal piece,End piece" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 79: Testis - Spermatogenesis" "Cluster 17: Choroid plexus - Cilium" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 6 "Primary cilium transition zone, Mid piece, Principal piece, End piece" "Nucleoplasm, Vesicles" "HPA039193: , HPA041830: " "potential prognostic favorable (2.74e-4)" "unprognostic (3.32e-1)" "unprognostic (7.34e-3)" "unprognostic (1.13e-1)" "unprognostic (7.73e-2)" "unprognostic (1.18e-1)" "unprognostic (5.54e-2)" "unprognostic (5.81e-2)" "unprognostic (9.42e-2)" "unprognostic (1.86e-2)" "unprognostic (1.19e-1)" "unprognostic (2.10e-2)" "unprognostic (4.87e-2)" "unprognostic (2.56e-1)" "unprognostic (4.42e-2)" RP2 "NM23-H10, NME10, TBCCD2" ENSG00000102218 "RP2 activator of ARL3 GTPase" O75695 X 46837043-46882358 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.7" "Cell type enhanced" "Detected in all" "Kupffer cells: 109.7;Monocyte progenitors: 164.7;monocytes: 175.1;Neutrophil progenitors: 261.9;Neutrophils: 524.8" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 175.1;Neutrophils: 524.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA000234, HPA000909" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane,Cytosol,Acrosome,Mid piece,Principal piece,End piece" NA NA 6700 "Cluster 40: Monocytes - Innate immune response" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 22: Non-specific - Mixed function" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 39 "Plasma membrane, Mid piece, Principal piece, End piece" "Nucleoplasm, Nuclear bodies, Vesicles, Cytosol, Acrosome" "HPA000234: , HPA000909: " "unprognostic (1.64e-1)" "unprognostic (6.29e-2)" "unprognostic (1.36e-1)" "unprognostic (1.77e-2)" "unprognostic (1.37e-2)" "unprognostic (7.54e-2)" "unprognostic (2.58e-1)" "unprognostic (8.19e-2)" "unprognostic (3.56e-1)" "unprognostic (4.88e-2)" "potential prognostic favorable (1.87e-7)" "unprognostic (2.20e-2)" "unprognostic (2.68e-1)" "potential prognostic unfavorable (6.72e-4)" "unprognostic (2.80e-1)" "unprognostic (3.31e-2)" "unprognostic (9.49e-2)" "unprognostic (8.98e-2)" "unprognostic (4.42e-1)" "unprognostic (1.53e-1)" "unprognostic (1.21e-2)" "unprognostic (3.15e-2)" "unprognostic (3.76e-1)" "unprognostic (1.19e-1)" "unprognostic (4.88e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-2)" "unprognostic (4.25e-2)" "unprognostic (2.80e-1)" "unprognostic (4.36e-2)" "unprognostic (2.37e-1)" RPAP2 "C1orf82, FLJ13150, Rtr1" ENSG00000122484 "RNA polymerase II associated protein 2" Q8IXW5 1 92299059-92402056 "Enzymes, Essential proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 560235.7;Collecting ducts: 169807.4;Distal tubules: 424662.4;Granulosa cells: 209468.3;Large ducts: 214899.6" "Tissue enriched" "Detected in single" 16776 "lymphoid tissue: 1677616.3" HPA046443 Approved Supported "Nucleoli,Primary cilium,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 100 "Nucleoli, Cytosol" "Primary cilium" "HPA046443: " "unprognostic (1.69e-1)" "unprognostic (1.27e-1)" "unprognostic (1.89e-1)" "unprognostic (1.11e-2)" "unprognostic (1.20e-1)" "unprognostic (1.26e-1)" "unprognostic (2.67e-2)" "unprognostic (2.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.06e-3)" "unprognostic (1.37e-1)" "unprognostic (4.05e-3)" "unprognostic (1.70e-1)" "unprognostic (2.46e-2)" "unprognostic (4.94e-3)" "unprognostic (1.63e-1)" "unprognostic (1.75e-1)" "unprognostic (1.00e-1)" "unprognostic (1.34e-1)" "unprognostic (7.65e-2)" "unprognostic (5.99e-2)" "unprognostic (3.02e-1)" "unprognostic (7.62e-2)" "unprognostic (2.37e-1)" "unprognostic (1.06e-2)" "unprognostic (3.47e-2)" "unprognostic (6.69e-2)" "unprognostic (4.23e-2)" "unprognostic (2.72e-1)" "unprognostic (1.97e-3)" "unprognostic (1.41e-1)" RPAP3 "FLJ21908, hSpagh, spag, Tah1" ENSG00000005175 "RNA polymerase II associated protein 3" Q9H6T3 12 47661249-47706030 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA038311, HPA038312" Enhanced Enhanced "Primary cilium,Primary cilium tip,Basal body,Cytosol,Acrosome" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 102 Cytosol "Primary cilium, Primary cilium tip, Basal body, Acrosome" "HPA038311: , HPA038312: " "unprognostic (2.85e-2)" "unprognostic (2.77e-2)" "unprognostic (2.74e-2)" "unprognostic (1.61e-1)" "unprognostic (3.05e-3)" "unprognostic (8.14e-2)" "unprognostic (2.83e-1)" "unprognostic (3.65e-1)" "unprognostic (7.57e-2)" "unprognostic (5.77e-2)" "potential prognostic favorable (2.33e-5)" "unprognostic (2.63e-1)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (8.42e-6)" "unprognostic (9.13e-2)" "unprognostic (4.18e-3)" "unprognostic (8.25e-3)" "unprognostic (2.07e-2)" "unprognostic (5.69e-2)" "unprognostic (2.87e-1)" "unprognostic (5.47e-3)" "unprognostic (4.66e-3)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (1.83e-2)" "unprognostic (4.79e-2)" "unprognostic (1.65e-1)" "unprognostic (8.06e-3)" "unprognostic (1.49e-1)" "unprognostic (4.11e-1)" "unprognostic (2.29e-2)" "unprognostic (2.01e-1)" RPF1 BXDC5 ENSG00000117133 "Ribosome production factor 1 homolog" Q9H9Y2 1 84479259-84498352 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "RNA-binding, rRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 197.3;Oocytes: 211.8" "Cell type enhanced" "Detected in all" "Oocytes: 211.8;Spermatogenic cell types: 197.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 917474.2;Neurons: 1014604.5" "Group enriched" "Detected in some" 5260 "intestine: 332207.7;lymphoid tissue: 719699.1" HPA024642 Supported Supported Nucleoli No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 47 Nucleoli "HPA024642: " "unprognostic (1.16e-1)" "unprognostic (8.41e-2)" "unprognostic (5.90e-3)" "unprognostic (7.04e-2)" "unprognostic (3.13e-3)" "unprognostic (2.20e-1)" "unprognostic (2.31e-2)" "unprognostic (8.09e-2)" "unprognostic (2.54e-1)" "potential prognostic unfavorable (5.30e-5)" "validated prognostic favorable (2.78e-5)" "validated prognostic favorable (5.63e-5)" "unprognostic (4.27e-2)" "potential prognostic unfavorable (1.10e-7)" "unprognostic (2.29e-3)" "unprognostic (3.00e-2)" "unprognostic (2.87e-2)" "unprognostic (4.31e-2)" "unprognostic (5.92e-2)" "unprognostic (6.09e-2)" "unprognostic (1.41e-1)" "unprognostic (1.75e-2)" "unprognostic (4.33e-1)" "unprognostic (1.10e-1)" "unprognostic (1.96e-2)" "unprognostic (1.64e-1)" "unprognostic (7.01e-2)" "unprognostic (3.70e-1)" "unprognostic (3.58e-2)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" RPF2 "bA397G5.4, BXDC1, FLJ21087" ENSG00000197498 "Ribosome production factor 2 homolog" Q9H7B2 6 110982015-111028263 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 192.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in many" "lymphoid tissue: 9241690.1" HPA035475 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 55: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 66 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA035475: " "potential prognostic unfavorable (4.91e-4)" "unprognostic (1.47e-3)" "unprognostic (4.21e-2)" "unprognostic (1.61e-2)" "unprognostic (3.00e-1)" "unprognostic (3.34e-2)" "unprognostic (1.20e-1)" "unprognostic (1.72e-1)" "potential prognostic unfavorable (4.13e-4)" "unprognostic (8.76e-3)" "unprognostic (3.63e-2)" "unprognostic (2.22e-1)" "unprognostic (4.00e-3)" "validated prognostic unfavorable (3.69e-6)" "validated prognostic unfavorable (9.97e-5)" "unprognostic (8.54e-3)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (2.11e-3)" "unprognostic (2.33e-2)" "unprognostic (4.02e-2)" "unprognostic (5.25e-3)" "unprognostic (3.90e-2)" "unprognostic (1.47e-3)" "unprognostic (3.04e-1)" "unprognostic (5.89e-2)" "unprognostic (1.70e-1)" "unprognostic (6.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.33e-1)" "unprognostic (5.86e-2)" "unprognostic (1.20e-1)" RPGRIP1 "CORD13, LCA6, RGI1, RPGRIP" ENSG00000092200 "RPGR interacting protein 1" Q96KN7 14 21280083-21351301 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Ciliopathy, Cone-rod dystrophy, Disease variant, Glaucoma, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 82 "retina: 171.2;testis: 55.4" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 979.2;Rod photoreceptor cells: 602.9" "Cell type enriched" "Detected in many" 5 "Neuronal cells: 979.2" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 11.9;hippocampal CA4: 3.3" "Cancer enriched" "Detected in single" 4 "Testicular Germ Cell Tumor (TCGA): 3.3" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "neutrophil: 8.8" "Group enriched" "Detected in many" 28 "dendritic cells: 3.2;granulocytes: 8.8;monocytes: 3.6" "Low cancer specificity" "Detected in single" "Breast - Breast glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 275 "lung: 27518.8" "HPA042955, HPA060190" Supported Supported Approved "Vesicles,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium tip,Cytosol" Yes NA "Cluster 21: Neutrophils - Unknown function" "Cluster 42: Retina - Visual perception" "Cluster 6: Non-specific - Immune response" "Cluster 1: Neuronal - Visual perception" "Cluster 79: Photoreceptor cells - Phototransduction" 28 "Vesicles, Microtubules, Primary cilium" "Cytokinetic bridge, Primary cilium tip, Cytosol" "HPA042955: , HPA060190: " "unprognostic (1.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.40e-2)" "unprognostic (1.20e-2)" "unprognostic (1.96e-1)" RPGRIP1L "CORS3, FTM, JBTS7, KIAA1005, MKS5, NPHP8, PPP1R134" ENSG00000103494 "RPGRIP1 like" Q68CZ1 16 53598153-53703938 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 12.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 98.0;Ependymal cells: 270.7;Fallopian tube ciliated cells: 85.7;Lactotrophs: 94.8;Respiratory ciliated cells: 177.4;Somatotrophs: 98.7;Thyrotrophs: 102.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 270.7;Pituitary endocrine cells: 102.7" "Cell type enhanced" "Detected in all" "ependymal cell: 306.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 11220651.2" "Tissue enriched" "Detected in some" "skin: 12518336.4" "HPA039405, HPA040530" Uncertain Approved "Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 34: Ciliated cells - Cilia assembly & function" 48 "Plasma membrane, Cytosol" "Primary cilium, Basal body" "HPA039405: , HPA040530: " "unprognostic (8.42e-2)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (2.13e-1)" "unprognostic (3.49e-2)" "unprognostic (9.20e-2)" "unprognostic (4.16e-2)" "unprognostic (1.17e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (2.00e-1)" "unprognostic (3.53e-3)" "unprognostic (1.33e-1)" "unprognostic (2.04e-1)" "potential prognostic unfavorable (8.49e-4)" "unprognostic (1.19e-1)" "unprognostic (3.29e-2)" "unprognostic (1.00e-1)" "unprognostic (1.45e-1)" "unprognostic (2.58e-1)" "unprognostic (1.38e-3)" "unprognostic (1.88e-3)" "unprognostic (3.00e-3)" "unprognostic (2.46e-2)" "potential prognostic favorable (4.08e-4)" "unprognostic (3.37e-1)" "unprognostic (1.35e-3)" "unprognostic (3.27e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (8.90e-4)" "unprognostic (1.24e-2)" RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 84.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 289.4;Esophageal apical cells: 284.9;Migrating cytotrophoblasts: 251.1;Syncytiotrophoblasts: 244.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 284.9;Trophoblast cells: 289.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islets: 15167473.7" "Low tissue specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 810000 "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 25 "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: , HPA057954: " "unprognostic (4.00e-2)" "unprognostic (3.75e-1)" "unprognostic (2.73e-1)" "unprognostic (5.92e-2)" "unprognostic (3.37e-2)" "potential prognostic favorable (6.92e-4)" "unprognostic (6.62e-2)" "unprognostic (1.41e-2)" "unprognostic (2.07e-2)" "unprognostic (7.29e-2)" "unprognostic (1.76e-2)" "unprognostic (4.97e-2)" "potential prognostic unfavorable (1.12e-4)" "validated prognostic unfavorable (2.30e-5)" "validated prognostic unfavorable (1.12e-5)" "unprognostic (1.73e-2)" "unprognostic (1.35e-1)" "unprognostic (9.64e-3)" "unprognostic (3.67e-2)" "unprognostic (3.06e-1)" "unprognostic (1.36e-1)" "unprognostic (4.17e-2)" "unprognostic (1.02e-1)" "unprognostic (9.15e-2)" "unprognostic (1.93e-1)" "unprognostic (1.76e-1)" "unprognostic (2.65e-2)" "unprognostic (8.12e-2)" "unprognostic (1.46e-1)" "unprognostic (6.48e-3)" "unprognostic (3.65e-1)" RPL18A L18A ENSG00000105640 "Ribosomal protein L18a" Q02543 19 17859910-17864153 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 9050.3;Esophageal basal cells: 8943.5;Esophageal suprabasal cells: 9700.7;Extravillous trophoblasts: 9623.0;Suprabasal keratinocytes: 7006.5" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 293.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Pancreas epithelial cells: 86207375.6;Pancreatic islets: 109629163.0" "Group enriched" "Detected in all" "lymphoid tissue: 60952840.3;pancreas: 79808286.0;salivary gland: 23312778.1" HPA055259 Approved Approved Nucleoplasm,Nucleoli,Cytosol No No 8200 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 165 Nucleoli "Nucleoplasm, Cytosol" "HPA055259: " "unprognostic (5.49e-3)" "unprognostic (4.15e-2)" "unprognostic (1.06e-3)" "unprognostic (7.87e-3)" "unprognostic (2.00e-1)" "unprognostic (4.88e-3)" "unprognostic (2.43e-2)" "potential prognostic favorable (8.13e-5)" "unprognostic (2.19e-1)" "unprognostic (3.24e-1)" "unprognostic (1.22e-2)" "unprognostic (1.84e-2)" "unprognostic (4.88e-3)" "validated prognostic unfavorable (1.22e-4)" "validated prognostic unfavorable (1.73e-5)" "unprognostic (3.02e-3)" "unprognostic (8.36e-2)" "unprognostic (4.09e-2)" "unprognostic (3.29e-1)" "unprognostic (1.81e-2)" "unprognostic (2.03e-1)" "unprognostic (1.03e-1)" "unprognostic (4.34e-1)" "unprognostic (2.25e-1)" "unprognostic (3.54e-2)" "unprognostic (1.25e-1)" "unprognostic (6.57e-2)" "unprognostic (4.03e-1)" "unprognostic (9.55e-2)" "unprognostic (5.11e-2)" "unprognostic (1.57e-1)" RPL19 "DKFZp779D216, FLJ27452, L19, MGC71997" ENSG00000108298 "Ribosomal protein L19" P84098 17 39200283-39204840 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal basal cells: 9460.9;Esophageal suprabasal cells: 9959.7;Gastric progenitor cells: 14562.4" "Cell type enhanced" "Detected in all" "Proliferating cells: 14562.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islets: 44328720.5;Skeletal myofibers: 44936502.3" "Tissue enhanced" "Detected in all" "pancreas: 260738043.9" "HPA043014, HPA051987" Approved Enhanced Nucleoli,Cytosol NA NA 47000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Protein processing" 421 "Nucleoli, Cytosol" "HPA043014: , HPA051987: " "unprognostic (3.39e-2)" "unprognostic (8.64e-2)" "unprognostic (2.08e-1)" "unprognostic (5.65e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-1)" "unprognostic (4.23e-2)" "unprognostic (1.80e-2)" "unprognostic (5.86e-3)" "unprognostic (2.17e-3)" "unprognostic (1.24e-2)" "unprognostic (1.26e-1)" "unprognostic (3.75e-3)" "validated prognostic unfavorable (1.05e-4)" "validated prognostic unfavorable (1.24e-4)" "unprognostic (4.50e-2)" "unprognostic (4.87e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.31e-3)" "unprognostic (1.04e-1)" "unprognostic (4.05e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "potential prognostic favorable (8.11e-5)" "unprognostic (1.80e-2)" "unprognostic (3.32e-2)" "unprognostic (1.15e-1)" "unprognostic (1.79e-1)" "unprognostic (2.14e-2)" "unprognostic (4.49e-2)" RPL22 "EAP, L22" ENSG00000116251 "Ribosomal protein L22" P35268 1 6185020-6209389 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Heparin-binding, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 1138.9;Gastric chief cells: 988.3;Parietal cells: 746.1" "Cell type enhanced" "Detected in all" "Myocytes: 1138.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 166644815.3;Pancreatic islets: 217965859.6" "Tissue enriched" "Detected in all" "pancreas: 245718810.4" HPA068294 Uncertain Nucleoplasm,Nucleoli NA NA 810000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 148 Nucleoli Nucleoplasm "HPA068294: " "unprognostic (5.65e-3)" "unprognostic (1.41e-2)" "unprognostic (9.61e-2)" "unprognostic (1.36e-2)" "unprognostic (2.26e-1)" "unprognostic (4.50e-2)" "unprognostic (1.41e-1)" "unprognostic (2.83e-2)" "unprognostic (3.89e-2)" "unprognostic (2.77e-3)" "potential prognostic favorable (2.14e-7)" "unprognostic (5.84e-2)" "unprognostic (1.13e-2)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (1.47e-7)" "unprognostic (2.45e-2)" "unprognostic (3.39e-2)" "unprognostic (6.36e-2)" "unprognostic (4.73e-1)" "unprognostic (2.40e-1)" "unprognostic (5.15e-2)" "unprognostic (9.11e-2)" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (3.78e-2)" "unprognostic (2.36e-2)" "unprognostic (1.83e-1)" "unprognostic (7.50e-2)" "unprognostic (2.27e-1)" "unprognostic (1.26e-1)" "unprognostic (4.45e-2)" RPL22L1 ENSG00000163584 "Ribosomal protein L22 like 1" Q6P5R6 3 170864875-170870208 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 457.7;Erythrocyte progenitors: 478.7;Esophageal basal cells: 806.6;Esophageal suprabasal cells: 693.9;Gastric progenitor cells: 542.1;Plasma cells: 452.8" "Cell type enhanced" "Detected in all" "Basal cells: 806.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" "lymphoid tissue: 642736.6;pancreas: 2218476.6" "HPA048060, HPA056207, HPA068294" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 16 Nucleoli "Nucleoplasm, Nucleoli rim" "HPA048060: , HPA056207: , HPA068294: " "potential prognostic unfavorable (1.02e-4)" "unprognostic (2.97e-1)" "unprognostic (2.25e-2)" "unprognostic (1.81e-1)" "unprognostic (1.46e-2)" "unprognostic (1.53e-1)" "unprognostic (6.71e-2)" "unprognostic (9.59e-2)" "unprognostic (3.10e-2)" "unprognostic (1.03e-1)" "validated prognostic unfavorable (4.11e-9)" "validated prognostic unfavorable (1.76e-6)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (6.07e-2)" "unprognostic (2.05e-1)" "unprognostic (3.00e-2)" "unprognostic (6.01e-3)" "unprognostic (8.77e-2)" "unprognostic (1.87e-1)" "unprognostic (4.60e-2)" "unprognostic (6.66e-3)" "unprognostic (2.45e-2)" "unprognostic (1.67e-2)" "unprognostic (1.09e-2)" "unprognostic (2.94e-1)" "unprognostic (2.41e-2)" "unprognostic (1.97e-1)" "unprognostic (2.49e-2)" "unprognostic (1.90e-1)" "unprognostic (1.22e-2)" "unprognostic (3.43e-2)" RPL3L ENSG00000140986 "Ribosomal protein L3 like" Q92901 16 1943974-1957606 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 165.9;skeletal muscle: 884.0;tongue: 394.7" "Cell type enriched" "Detected in some" 5 "Myonuclei: 352.0" "Cell type enriched" "Detected in many" 5 "Myocytes: 352.0" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" "Capillaries: 27491117.7;Cardiomyocytes: 33996012.5;Pancreas epithelial cells: 48049145.7;Pancreatic islets: 57014849.4;Skeletal myofibers: 21838488.9" "Tissue enriched" "Detected in some" "pancreas: 26620854.9" HPA049136 Enhanced Approved "Nuclear speckles" NA NA "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 4 "Nuclear speckles" "HPA049136: " "unprognostic (2.27e-1)" "unprognostic (5.38e-3)" "unprognostic (1.93e-2)" "unprognostic (4.53e-2)" "unprognostic (3.64e-1)" "unprognostic (3.69e-2)" "unprognostic (3.06e-1)" "unprognostic (3.45e-1)" RPL4 L4 ENSG00000174444 "Ribosomal protein L4" P36578 15 66498015-66524532 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 3939.5;Esophageal basal cells: 3105.4;Esophageal suprabasal cells: 3042.4;Extravillous trophoblasts: 4187.2;Migrating cytotrophoblasts: 3127.0" "Cell type enhanced" "Detected in all" "Stromal cells: 3939.5;Trophoblast cells: 4187.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Pancreas epithelial cells: 769765592.8;Pancreatic islets: 801124327.5" "Tissue enhanced" "Detected in all" "pancreas: 701306037.7" HPA034600 Uncertain Supported "Nucleoli,Nuclear bodies,Endoplasmic reticulum,Cytosol" Yes No 380000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 55: Non-specific - Transcription" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 505 "Endoplasmic reticulum, Cytosol" "Nucleoli, Nuclear bodies" "HPA034600: " "unprognostic (8.19e-3)" "unprognostic (2.22e-1)" "unprognostic (6.60e-3)" "unprognostic (2.02e-1)" "unprognostic (2.62e-1)" "unprognostic (1.33e-1)" "unprognostic (1.31e-2)" "unprognostic (1.40e-3)" "unprognostic (3.15e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.24e-7)" "unprognostic (4.96e-3)" "unprognostic (4.94e-2)" "unprognostic (3.36e-3)" "potential prognostic unfavorable (3.69e-7)" "potential prognostic unfavorable (6.65e-4)" "unprognostic (3.06e-3)" "unprognostic (1.33e-1)" "unprognostic (2.70e-1)" "unprognostic (2.20e-2)" "unprognostic (8.93e-2)" "unprognostic (1.41e-1)" "unprognostic (7.87e-2)" "unprognostic (1.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.58e-1)" "unprognostic (2.06e-1)" "unprognostic (3.78e-1)" "unprognostic (2.01e-1)" "unprognostic (6.87e-2)" RPN1 OST1 ENSG00000163902 "Ribophorin I" P04843 3 128619969-128681075 "Cancer-related genes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Macrophages, Heart muscle - Macrophages, Liver - Hepatocytes, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 1266875052.4;Pancreatic islets: 929597854.9" "Tissue enhanced" "Detected in all" "pancreas: 607529767.6" "CAB009748, HPA026828, HPA051520" Enhanced Enhanced "Endoplasmic reticulum,Cytosol" NA NA 460000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 246 "Endoplasmic reticulum" Cytosol "CAB009748: , HPA026828: , HPA051520: " "unprognostic (1.09e-1)" "unprognostic (6.71e-2)" "unprognostic (2.56e-2)" "unprognostic (2.06e-1)" "unprognostic (1.88e-1)" "unprognostic (1.34e-1)" "unprognostic (6.99e-2)" "unprognostic (2.10e-1)" "unprognostic (3.14e-2)" "unprognostic (2.71e-3)" "unprognostic (6.29e-3)" "unprognostic (3.62e-2)" "unprognostic (7.09e-2)" "validated prognostic unfavorable (1.61e-5)" "validated prognostic unfavorable (1.89e-6)" "unprognostic (9.03e-2)" "unprognostic (7.44e-3)" "unprognostic (2.93e-1)" "unprognostic (2.56e-2)" "unprognostic (2.45e-1)" "unprognostic (3.08e-1)" "unprognostic (1.60e-3)" "unprognostic (5.72e-1)" "unprognostic (1.26e-1)" "unprognostic (2.84e-1)" "unprognostic (2.60e-1)" "unprognostic (1.82e-1)" "unprognostic (1.35e-1)" "unprognostic (4.75e-2)" "unprognostic (1.83e-1)" "unprognostic (5.23e-2)" RPN2 "RIBIIR, RPN-II, RPNII, SWP1" ENSG00000118705 "Ribophorin II" P04844 20 37178410-37241619 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 858.8;Oocytes: 1128.2;Plasma cells: 576.8;Syncytiotrophoblasts: 802.1" "Cell type enhanced" "Detected in all" "Oocytes: 1128.2;Trophoblast cells: 858.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Macrophages, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Neutrophils: 189769923.8;Pancreas epithelial cells: 702776384.7;Pancreatic islets: 610141386.8" "Tissue enhanced" "Detected in all" "pancreas: 320384079.9" "HPA008297, CAB019277, HPA025922" Enhanced Supported "Endoplasmic reticulum" NA NA 1300000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 22: Epididymis - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 8: Non-specific - Secretory pathway" 197 "Endoplasmic reticulum" "CAB019277: , HPA008297: , HPA025922: " "unprognostic (3.35e-1)" "unprognostic (1.22e-3)" "unprognostic (7.30e-2)" "unprognostic (4.50e-2)" "unprognostic (5.85e-2)" "unprognostic (2.05e-1)" "unprognostic (1.77e-1)" "unprognostic (9.27e-2)" "unprognostic (1.78e-2)" "potential prognostic unfavorable (7.02e-6)" "unprognostic (2.60e-3)" "potential prognostic unfavorable (2.48e-4)" "unprognostic (1.75e-1)" "validated prognostic unfavorable (1.94e-4)" "validated prognostic unfavorable (6.08e-4)" "unprognostic (7.76e-2)" "unprognostic (3.11e-2)" "unprognostic (5.93e-2)" "unprognostic (6.79e-2)" "unprognostic (1.91e-1)" "unprognostic (1.48e-1)" "unprognostic (9.73e-2)" "unprognostic (2.36e-1)" "unprognostic (3.29e-1)" "unprognostic (7.46e-2)" "unprognostic (4.11e-2)" "unprognostic (3.42e-1)" "unprognostic (1.45e-1)" "unprognostic (3.68e-2)" "unprognostic (1.04e-1)" "unprognostic (8.22e-2)" RPS19 "DBA, eS19, LOH19CR1, S19" ENSG00000105372 "Ribosomal protein S19" P39019 19 41860255-41872925 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Host-virus interaction" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 10268.9;Esophageal basal cells: 11343.2;Esophageal suprabasal cells: 13540.1;Extravillous trophoblasts: 11782.2;Migrating cytotrophoblasts: 10321.5;Suprabasal keratinocytes: 11649.1" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "leukocyte: 623.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Pancreas epithelial cells: 420578880.6;Pancreatic islets: 516468248.8" "Tissue enhanced" "Detected in all" "pancreas: 546129130.8" HPA063217 Supported Nucleoplasm NA NA 37000 "Cluster 18: Non-specific - Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 344 Nucleoplasm "HPA063217: " "unprognostic (2.02e-2)" "unprognostic (9.00e-3)" "unprognostic (1.72e-1)" "unprognostic (2.47e-2)" "unprognostic (1.34e-1)" "unprognostic (2.62e-2)" "unprognostic (2.76e-3)" "unprognostic (2.34e-1)" "unprognostic (5.69e-2)" "unprognostic (8.20e-2)" "unprognostic (2.15e-3)" "unprognostic (3.12e-3)" "potential prognostic unfavorable (6.05e-4)" "unprognostic (4.74e-2)" "unprognostic (1.19e-3)" "unprognostic (2.67e-3)" "unprognostic (4.18e-2)" "unprognostic (2.72e-2)" "unprognostic (9.48e-2)" "unprognostic (5.40e-2)" "unprognostic (1.09e-2)" "unprognostic (2.48e-2)" "unprognostic (2.69e-1)" "unprognostic (1.17e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-2)" "unprognostic (1.31e-1)" "unprognostic (2.44e-1)" "unprognostic (2.54e-1)" "unprognostic (2.44e-1)" "unprognostic (1.30e-1)" RPS19BP1 "FLJ21770, MGC52010" ENSG00000187051 "Ribosomal protein S19 binding protein 1" Q86WX3 22 39529093-39532761 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 2775237.5;T-cells: 5246365.6" "Group enriched" "Detected in some" "fallopian tube: 21885.7;intestine: 55075.6;lymphoid tissue: 47991.3;Stomach: 36863.2" HPA042874 Uncertain Supported Nucleoplasm,Nucleoli,Cytosol NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 31 Nucleoli "Nucleoplasm, Cytosol" "HPA042874: " "unprognostic (3.95e-1)" "unprognostic (1.48e-1)" "unprognostic (2.86e-1)" "unprognostic (3.49e-1)" "unprognostic (4.45e-2)" "unprognostic (2.35e-1)" "unprognostic (4.45e-2)" "unprognostic (2.70e-1)" "unprognostic (2.14e-1)" "unprognostic (9.28e-3)" "unprognostic (7.60e-2)" "unprognostic (3.88e-2)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (1.12e-4)" "unprognostic (2.75e-3)" "unprognostic (3.31e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-2)" "unprognostic (1.35e-1)" "unprognostic (2.40e-1)" "unprognostic (3.14e-1)" "unprognostic (2.58e-1)" "unprognostic (1.96e-1)" "unprognostic (1.23e-1)" "unprognostic (8.52e-2)" "unprognostic (5.63e-2)" "unprognostic (3.17e-1)" "unprognostic (2.07e-1)" "unprognostic (1.36e-1)" "unprognostic (2.32e-1)" "unprognostic (1.57e-1)" RPS24 "eS24, S24" ENSG00000138326 "Ribosomal protein S24" P62847 10 78033760-78056813 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal suprabasal cells: 8920.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 25117068.9;Pancreatic islets: 36522742.9" "Tissue enhanced" "Detected in all" "pancreas: 64009415.2" "HPA003364, HPA073508" Approved Enhanced "Endoplasmic reticulum,Cytosol" NA NA 29000 "Cluster 30: Non-specific - DNA binding" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 142 "Endoplasmic reticulum, Cytosol" "HPA003364: , HPA073508: " "unprognostic (1.75e-2)" "unprognostic (1.58e-3)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" "unprognostic (5.46e-2)" "unprognostic (3.84e-2)" "unprognostic (8.45e-2)" "unprognostic (1.26e-3)" "unprognostic (1.00e-2)" "unprognostic (1.80e-1)" "unprognostic (4.36e-3)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (3.80e-4)" "unprognostic (2.60e-2)" "unprognostic (2.61e-3)" "unprognostic (1.64e-2)" "unprognostic (1.79e-2)" "unprognostic (6.96e-3)" "unprognostic (5.12e-2)" "unprognostic (1.30e-1)" "unprognostic (5.36e-3)" "unprognostic (1.31e-2)" "unprognostic (8.79e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (9.00e-2)" "unprognostic (2.32e-1)" "unprognostic (2.44e-1)" "unprognostic (2.95e-2)" "unprognostic (1.30e-1)" RPS25 S25 ENSG00000118181 "Ribosomal protein S25" P62851 11 119015712-119018691 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Enteric stem cells: 3021.1;Epididymal efferent duct absorptive cells: 3610.7;Gastric chief cells: 3153.8;Ovarian stromal cells: 3254.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 409915429.8" "Tissue enhanced" "Detected in all" "pancreas: 320688263.9" "HPA031801, HPA078683" Approved Supported "Nucleoli,Endoplasmic reticulum,Cytosol" NA NA 47000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 156 "Endoplasmic reticulum, Cytosol" Nucleoli "HPA031801: , HPA078683: " "unprognostic (1.24e-2)" "unprognostic (4.62e-2)" "unprognostic (3.35e-2)" "unprognostic (6.84e-3)" "unprognostic (1.74e-1)" "unprognostic (2.00e-2)" "unprognostic (1.55e-1)" "unprognostic (4.76e-2)" "unprognostic (2.39e-3)" "unprognostic (1.26e-1)" "unprognostic (9.02e-2)" "unprognostic (4.89e-2)" "unprognostic (1.46e-2)" "unprognostic (2.43e-3)" "potential prognostic unfavorable (8.08e-4)" "unprognostic (3.62e-2)" "unprognostic (5.44e-3)" "unprognostic (5.80e-3)" "unprognostic (1.33e-1)" "unprognostic (1.01e-2)" "unprognostic (1.04e-1)" "unprognostic (1.00e-2)" "unprognostic (6.40e-2)" "unprognostic (6.50e-2)" "unprognostic (7.75e-3)" "unprognostic (2.98e-1)" "unprognostic (1.87e-2)" "unprognostic (1.02e-1)" "unprognostic (4.95e-1)" "unprognostic (5.17e-2)" "unprognostic (1.87e-1)" RPS28 "eS28, S28" ENSG00000233927 "Ribosomal protein S28" P62857 19 8321158-8323340 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Diamond-Blackfan anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast secretory cells: 7410.0;Gastric chief cells: 9108.8;Parietal cells: 7046.8" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "leukocyte: 831.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 141591066.3;Pancreatic islets: 129567637.9" "Low tissue specificity" "Detected in all" HPA047132 Approved Approved Cytosol NA NA 1000000 "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 113 Cytosol "HPA047132: " "unprognostic (6.63e-2)" "unprognostic (1.58e-2)" "unprognostic (2.23e-1)" "unprognostic (4.56e-3)" "unprognostic (1.06e-1)" "unprognostic (1.83e-2)" "unprognostic (5.63e-2)" "potential prognostic favorable (1.46e-4)" "unprognostic (6.26e-2)" "unprognostic (1.18e-1)" "potential prognostic favorable (1.47e-5)" "unprognostic (7.57e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (2.64e-6)" "unprognostic (7.16e-2)" "unprognostic (4.75e-2)" "unprognostic (3.26e-1)" "unprognostic (2.11e-1)" "unprognostic (5.88e-2)" "unprognostic (1.75e-1)" "unprognostic (8.82e-3)" "unprognostic (5.48e-3)" "unprognostic (2.42e-2)" "unprognostic (9.84e-2)" "unprognostic (8.50e-2)" "unprognostic (1.20e-2)" "unprognostic (9.51e-2)" "unprognostic (1.75e-1)" "unprognostic (4.51e-2)" "unprognostic (3.04e-1)" RPS3A "MFTL, S3A" ENSG00000145425 "Ribosomal protein S3A" P61247 4 151099624-151104642 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" Differentiation "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Decidual stromal cells: 8451.6;Esophageal suprabasal cells: 8044.3;Extravillous trophoblasts: 7545.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 275234116.5;Pancreatic islets: 268427534.2" "Low tissue specificity" "Detected in all" "HPA047100, HPA053454" Approved Enhanced "Nucleoli,Endoplasmic reticulum,Cytosol" No No 270000 "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 7: Non-specific - Ribosome" "Cluster 25: Non-specific - Ribosome" "Cluster 15: Non-specific - Protein processing" 224 "Nucleoli, Endoplasmic reticulum, Cytosol" "HPA047100: , HPA053454: " "unprognostic (9.99e-3)" "unprognostic (1.73e-2)" "unprognostic (1.88e-2)" "unprognostic (1.27e-2)" "unprognostic (3.32e-1)" "unprognostic (6.33e-2)" "unprognostic (6.99e-2)" "unprognostic (3.43e-1)" "unprognostic (3.93e-2)" "unprognostic (1.05e-1)" "validated prognostic favorable (7.18e-6)" "validated prognostic favorable (5.96e-4)" "unprognostic (4.85e-2)" "potential prognostic unfavorable (4.66e-4)" "unprognostic (1.43e-2)" "unprognostic (2.44e-1)" "unprognostic (9.72e-3)" "unprognostic (6.65e-2)" "unprognostic (8.15e-3)" "unprognostic (2.10e-2)" "unprognostic (2.17e-3)" "unprognostic (1.43e-2)" "unprognostic (2.00e-2)" "unprognostic (2.50e-1)" "unprognostic (4.00e-3)" "unprognostic (2.45e-1)" "unprognostic (1.29e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "unprognostic (1.76e-1)" "unprognostic (4.29e-2)" RPS6KA1 "HU-1, MAPKAPK1, p90Rsk, RSK1" ENSG00000117676 "Ribosomal protein S6 kinase A1" Q15418 1 26529761-26575030 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Host-virus interaction, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 14.6;Distal convoluted tubule cells: 18.4;Loop of henle epithelial cells: 19.3;Microglia: 80.3;Oligodendrocytes: 15.1;Papillary tip epithelial cells: 17.9;Proximal tubule cells: 33.8;Renal collecting duct intercalated cells: 23.8;Renal collecting duct principal cells: 19.4;Renal connecting tubule cells: 29.9" "Cell type enhanced" "Detected in many" "Ductal cells: 29.9;Glial cells: 80.3;Renal nephron cells: 33.8" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 100.2;leukocyte: 62.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Pituitary gland - Corticotropes, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 16095538.5" "Low tissue specificity" "Detected in many" "CAB003852, HPA007981" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 6: Non-specific - Immune response" "Cluster 37: Non-specific - mRNA processing" "Cluster 102: Non-specific - Mixed function" 41 Cytosol Nucleoplasm "CAB003852: , HPA007981: " "unprognostic (3.63e-1)" "unprognostic (3.43e-2)" "unprognostic (2.32e-1)" "unprognostic (1.19e-2)" "unprognostic (2.40e-3)" "unprognostic (8.88e-3)" "unprognostic (3.57e-1)" "unprognostic (4.83e-2)" "unprognostic (1.96e-1)" "unprognostic (1.41e-2)" "unprognostic (2.56e-3)" "unprognostic (1.80e-1)" "potential prognostic favorable (4.65e-6)" "unprognostic (2.67e-2)" "unprognostic (7.12e-2)" "unprognostic (1.60e-3)" "unprognostic (5.94e-2)" "unprognostic (5.30e-3)" "unprognostic (4.27e-1)" "unprognostic (5.84e-3)" "unprognostic (3.08e-1)" "unprognostic (6.90e-3)" "unprognostic (5.00e-2)" "unprognostic (1.41e-1)" "unprognostic (4.22e-1)" "unprognostic (4.13e-2)" "unprognostic (5.42e-2)" "unprognostic (4.89e-3)" "unprognostic (3.42e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-2)" RPS6KA3 "CLS, HU-3, MRX19, RSK2" ENSG00000177189 "Ribosomal protein S6 kinase A3" P51812 X 20149911-20267519 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 586.0;Neutrophils: 1334.8;Ocular epithelial cells: 574.8" "Cell type enhanced" "Detected in all" "Neutrophils: 1334.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA003221, CAB003853, CAB013520" Approved Supported Nucleoplasm,Nucleoli,Vesicles,Cytosol No No 6700 "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 18: Liver cancer - Metabolism" "Cluster 24: Neutrophils - Innate immunity signal integration" 48 Nucleoplasm "Nucleoli, Vesicles, Cytosol" "CAB003853: , CAB013520: , HPA003221: " "unprognostic (7.49e-2)" "unprognostic (1.19e-2)" "unprognostic (8.02e-3)" "unprognostic (1.15e-2)" "unprognostic (1.13e-2)" "unprognostic (7.44e-2)" "unprognostic (1.25e-1)" "unprognostic (5.60e-3)" "unprognostic (1.91e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (5.86e-6)" "unprognostic (3.35e-2)" "unprognostic (1.76e-1)" "unprognostic (2.36e-3)" "unprognostic (2.09e-3)" "unprognostic (6.10e-2)" "unprognostic (4.58e-2)" "unprognostic (2.70e-1)" "unprognostic (3.79e-2)" "unprognostic (6.51e-3)" "unprognostic (3.76e-2)" "unprognostic (7.42e-2)" "unprognostic (3.38e-2)" "unprognostic (1.59e-1)" "unprognostic (1.28e-2)" "unprognostic (2.41e-1)" "unprognostic (1.78e-1)" "unprognostic (6.95e-3)" "unprognostic (2.16e-1)" "unprognostic (4.21e-1)" "unprognostic (2.49e-1)" RPS6KA4 "MSK2, RSK-B" ENSG00000162302 "Ribosomal protein S6 kinase A4" O75676 11 64359148-64372215 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Inflammatory response, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 54.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.5;Cytotrophoblasts: 85.6;Migrating cytotrophoblasts: 87.7;pDCs: 133.1;Syncytiotrophoblasts: 48.0" "Cell type enhanced" "Detected in many" "dendritic cells: 133.1;Trophoblast cells: 87.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.5" "Group enriched" "Detected in many" 5 "dendritic cells: 10.5;monocytes: 2.7" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 16614280.9" "Tissue enriched" "Detected in some" "intestine: 14590318.8" "CAB008649, HPA023225" Approved Supported Nucleoplasm,Cytosol No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 37 Nucleoplasm Cytosol "CAB008649: , HPA023225: " "unprognostic (2.31e-2)" "unprognostic (2.84e-1)" "potential prognostic favorable (2.41e-5)" "unprognostic (3.07e-2)" "unprognostic (1.88e-1)" "unprognostic (9.29e-3)" "unprognostic (2.61e-1)" "unprognostic (6.32e-2)" "unprognostic (3.62e-2)" "unprognostic (7.78e-2)" "unprognostic (3.47e-2)" "unprognostic (5.15e-3)" "unprognostic (8.26e-2)" "potential prognostic unfavorable (7.75e-5)" "unprognostic (4.87e-1)" "unprognostic (1.65e-3)" "unprognostic (5.68e-3)" "unprognostic (4.18e-2)" "unprognostic (4.73e-2)" "unprognostic (2.52e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" "unprognostic (5.77e-3)" "unprognostic (2.23e-1)" "unprognostic (7.31e-2)" "unprognostic (2.83e-1)" "unprognostic (1.87e-2)" "unprognostic (1.80e-1)" "unprognostic (9.72e-2)" "unprognostic (2.33e-1)" RPUSD4 FLJ14494 ENSG00000165526 "RNA pseudouridine synthase D4" Q96CM3 11 126202096-126211692 "Metabolic proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, rRNA processing, tRNA processing" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 126.8;tongue: 70.1" "Cell type enhanced" "Detected in many" "Myonuclei: 55.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 406552.4" "Not detected" "Not detected" HPA039689 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 21: Non-specific - Metabolism" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 53 Mitochondria Nucleoplasm "HPA039689: " "unprognostic (1.30e-1)" "unprognostic (1.91e-2)" "unprognostic (2.63e-2)" "unprognostic (1.70e-1)" "unprognostic (1.19e-1)" "unprognostic (1.07e-2)" "unprognostic (4.07e-2)" "potential prognostic favorable (2.13e-4)" "unprognostic (2.88e-2)" "unprognostic (2.20e-1)" "potential prognostic favorable (1.66e-6)" "unprognostic (1.06e-3)" "unprognostic (1.03e-1)" "validated prognostic unfavorable (7.75e-6)" "validated prognostic unfavorable (3.31e-5)" "unprognostic (2.56e-2)" "potential prognostic unfavorable (4.64e-6)" "unprognostic (6.81e-2)" "unprognostic (2.10e-1)" "unprognostic (2.63e-2)" "unprognostic (3.30e-1)" "unprognostic (5.04e-3)" "unprognostic (3.88e-2)" "unprognostic (1.23e-2)" "unprognostic (1.89e-2)" "unprognostic (3.33e-2)" "unprognostic (2.37e-3)" "unprognostic (1.71e-1)" "unprognostic (3.17e-1)" "unprognostic (2.40e-1)" "unprognostic (3.36e-2)" RRAGD "bA11D8.2.1, DKFZP761H171" ENSG00000025039 "Ras related GTP binding D" Q9NQL2 6 89364616-89412273 "Human disease related genes, Predicted intracellular proteins" Hydrolase "Cardiomyopathy, Disease variant, Primary hypomagnesemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 79.1;tongue: 56.3" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 140.8;Esophageal apical cells: 208.6;Esophageal suprabasal cells: 178.4;Myonuclei: 144.0;Neutrophil progenitors: 165.2;Neutrophils: 164.7;Salivary acinar cells: 250.4;Salivary duct cells: 253.7" "Cell type enhanced" "Detected in many" "Acinar cells: 250.4;Ductal cells: 253.7" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 53.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.3" "Group enriched" "Detected in many" 7 "granulocytes: 3.3;monocytes: 2.4" "Cancer enhanced" "Detected in many" "Myeloma: 28.0" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" HPA068664 Approved Approved Nucleoplasm,Vesicles,Centrosome NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 23 Nucleoplasm "Vesicles, Centrosome" "HPA068664: " "unprognostic (5.37e-2)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (8.11e-2)" "unprognostic (8.62e-3)" "unprognostic (5.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.45e-1)" "unprognostic (1.90e-1)" "unprognostic (5.16e-3)" "validated prognostic favorable (2.57e-8)" "validated prognostic favorable (5.98e-4)" "unprognostic (6.05e-2)" "unprognostic (1.64e-3)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (8.30e-3)" "unprognostic (6.42e-2)" "unprognostic (5.79e-1)" "unprognostic (2.01e-1)" "unprognostic (4.48e-2)" "unprognostic (1.93e-1)" "unprognostic (3.47e-3)" "unprognostic (1.52e-3)" "unprognostic (1.07e-1)" "unprognostic (1.75e-2)" "unprognostic (1.88e-1)" "unprognostic (2.12e-2)" "potential prognostic unfavorable (5.84e-4)" "unprognostic (2.33e-1)" "unprognostic (3.45e-2)" "unprognostic (1.39e-1)" RRM1 ENSG00000167325 "Ribonucleotide reductase catalytic subunit M1" P23921 11 4094707-4138932 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Deoxyribonucleotide synthesis" "Allosteric enzyme, Oxidoreductase" "FDA approved drug targets, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 167.9;Erythrocyte progenitors: 209.6;Monocyte progenitors: 148.4" "Cell type enhanced" "Detected in many" "Erythrocytes: 209.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 14607426.4;Oocytes: 9029128.9" "Group enriched" "Detected in many" "bone marrow: 14008842.5;intestine: 4771877.8;pancreas: 16263930.3" "CAB022093, HPA057265, HPA064297" Enhanced Supported "Plasma membrane,Centriolar satellite,Basal body,Cytosol" NA Yes 150000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 15 Cytosol "Plasma membrane, Centriolar satellite, Basal body" "CAB022093: , HPA057265: , HPA064297: " "unprognostic (6.58e-3)" "unprognostic (6.05e-2)" "unprognostic (2.46e-2)" "unprognostic (9.03e-2)" "unprognostic (3.74e-3)" "unprognostic (1.93e-1)" "unprognostic (4.89e-1)" "unprognostic (3.01e-2)" "unprognostic (1.33e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (1.26e-7)" "unprognostic (3.41e-1)" "unprognostic (1.83e-1)" "unprognostic (1.33e-2)" "potential prognostic unfavorable (2.18e-4)" "unprognostic (8.65e-3)" "potential prognostic unfavorable (4.80e-6)" "unprognostic (1.68e-1)" "unprognostic (1.34e-1)" "unprognostic (3.67e-1)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (4.50e-5)" "unprognostic (1.95e-1)" "unprognostic (5.11e-2)" "unprognostic (4.07e-3)" "unprognostic (1.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.69e-2)" "unprognostic (2.12e-1)" "unprognostic (4.94e-2)" "unprognostic (1.76e-2)" RRM2 "C2orf48, FLJ25102" ENSG00000171848 "Ribonucleotide reductase regulatory subunit M2" P31350 2 10120698-10211725 "Enzymes, Essential proteins, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Deoxyribonucleotide synthesis" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.5;lymphoid tissue: 54.1" "Cell type enhanced" "Detected in many" "Enteric transient amplifying cells: 146.4;Erythrocyte progenitors: 193.2;Esophageal basal cells: 170.2;Extravillous trophoblasts: 335.6;Gastric progenitor cells: 139.7;Megakaryocyte progenitors: 121.7;Migrating cytotrophoblasts: 131.4;Monocyte progenitors: 409.0;Neutrophil progenitors: 279.3;Paneth cells: 92.8;Plasma cells: 117.5" "Cell type enhanced" "Detected in many" "Erythrocytes: 193.2;Mononuclear phagocytes: 409.0;Neutrophils: 279.3;Trophoblast cells: 335.6" "Cell type enhanced" "Detected in many" "leukocyte: 13.3;upper-layer intratelencephalic: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Granulosa cells: 3701155.7;Neutrophils: 1684554.5;T-cells: 1246019.0" "Group enriched" "Detected in some" "bone marrow: 3666441.8;liver: 6978626.0" HPA056994 Enhanced Supported Nucleoplasm,Cytosol Yes Yes 14000 "Cluster 15: NK-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 23 Cytosol Nucleoplasm "HPA056994: " "unprognostic (3.20e-1)" "unprognostic (5.87e-2)" "unprognostic (3.48e-1)" "unprognostic (2.04e-1)" "unprognostic (3.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.91e-1)" "unprognostic (7.09e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (1.93e-4)" "validated prognostic unfavorable (2.93e-7)" "validated prognostic unfavorable (1.59e-7)" "potential prognostic unfavorable (1.54e-11)" "validated prognostic unfavorable (4.94e-7)" "validated prognostic unfavorable (1.47e-8)" "potential prognostic unfavorable (8.75e-8)" "unprognostic (7.78e-3)" "unprognostic (5.95e-3)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (8.91e-2)" "potential prognostic unfavorable (3.66e-5)" "unprognostic (9.28e-3)" "unprognostic (8.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.73e-2)" "unprognostic (3.35e-3)" "unprognostic (1.30e-2)" "unprognostic (4.74e-1)" "unprognostic (6.25e-2)" "unprognostic (2.07e-1)" RRP1 "D21S2056E, NNP-1, Nop52, RRP1A" ENSG00000160214 "Ribosomal RNA processing 1" P56182 21 43789513-43805293 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 87.0;Esophageal suprabasal cells: 80.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "bone marrow: 23155074.6;fallopian tube: 9961809.5;intestine: 7982452.1;lymphoid tissue: 14145074.7" "HPA016818, HPA018166" Approved Enhanced "Nucleoli,Mitotic chromosome" Yes No 46000 "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 17: Non-specific - RNA processing" 32 "Nucleoli, Mitotic chromosome" "HPA016818: , HPA018166: " "unprognostic (3.13e-2)" "unprognostic (1.28e-1)" "unprognostic (5.37e-2)" "unprognostic (3.34e-1)" "unprognostic (4.79e-2)" "unprognostic (2.48e-1)" "unprognostic (1.95e-1)" "unprognostic (1.29e-3)" "unprognostic (7.86e-2)" "unprognostic (6.90e-2)" "unprognostic (9.28e-2)" "unprognostic (7.60e-2)" "unprognostic (7.11e-2)" "potential prognostic unfavorable (9.45e-5)" "unprognostic (2.98e-3)" "unprognostic (6.80e-2)" "unprognostic (1.42e-3)" "unprognostic (3.41e-2)" "unprognostic (2.12e-1)" "unprognostic (6.32e-2)" "unprognostic (2.64e-1)" "unprognostic (1.42e-1)" "unprognostic (2.18e-1)" "unprognostic (6.41e-3)" "unprognostic (4.53e-2)" "unprognostic (1.01e-2)" "unprognostic (1.14e-1)" "unprognostic (2.93e-1)" "unprognostic (8.23e-2)" "unprognostic (1.21e-1)" "unprognostic (8.09e-2)" RRP12 KIAA0690 ENSG00000052749 "Ribosomal RNA processing 12 homolog" Q5JTH9 10 97356358-97426076 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 85.9;skeletal muscle: 36.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 222.4;Monocyte progenitors: 319.4;monocytes: 176.4;Neutrophil progenitors: 288.4;Neutrophils: 284.8" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 319.4;Neutrophils: 288.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 26.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 32148338.4" "Low tissue specificity" "Detected in many" "HPA049945, HPA074403" Supported "Nucleoli,Vesicles,Plasma membrane,Cytosol" No No 4300 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 43 Nucleoli "Vesicles, Plasma membrane, Cytosol" "HPA049945: , HPA074403: " "unprognostic (2.85e-1)" "unprognostic (4.86e-2)" "unprognostic (5.33e-2)" "unprognostic (2.65e-3)" "unprognostic (1.80e-2)" "unprognostic (8.62e-2)" "unprognostic (2.60e-1)" "unprognostic (1.45e-3)" "unprognostic (6.96e-2)" "unprognostic (1.24e-1)" "unprognostic (5.74e-2)" "unprognostic (6.68e-3)" "unprognostic (2.37e-1)" "potential prognostic unfavorable (8.08e-9)" "unprognostic (1.28e-3)" "unprognostic (7.72e-2)" "unprognostic (1.71e-2)" "unprognostic (3.35e-1)" "unprognostic (1.83e-1)" "unprognostic (5.74e-2)" "unprognostic (2.76e-1)" "unprognostic (1.51e-1)" "unprognostic (1.26e-1)" "unprognostic (7.69e-3)" "unprognostic (3.30e-2)" "unprognostic (1.98e-2)" "unprognostic (8.18e-2)" "unprognostic (2.43e-2)" "unprognostic (4.21e-1)" "unprognostic (1.45e-2)" "unprognostic (8.65e-2)" RRP15 "CGI-115, KIAA0507" ENSG00000067533 "Ribosomal RNA processing 15 homolog" Q9Y3B9 1 218285293-218337983 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1106504.2;T-cells: 3283897.8" "Tissue enhanced" "Detected in some" "lymphoid tissue: 312216.1;ovary: 451166.0" HPA024639 Approved Approved "Nucleoplasm,Nucleoli rim,Mitotic chromosome,Mitochondria" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 44 "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Mitochondria" "HPA024639: " "unprognostic (7.24e-2)" "unprognostic (1.91e-2)" "unprognostic (2.01e-1)" "unprognostic (2.64e-2)" "unprognostic (1.80e-1)" "unprognostic (4.90e-1)" "unprognostic (4.74e-2)" "unprognostic (1.35e-1)" "unprognostic (1.40e-2)" "unprognostic (4.02e-3)" "unprognostic (3.03e-2)" "unprognostic (2.32e-1)" "unprognostic (3.44e-2)" "potential prognostic unfavorable (2.15e-4)" "unprognostic (2.68e-2)" "unprognostic (6.74e-2)" "unprognostic (5.70e-2)" "unprognostic (2.17e-1)" "unprognostic (4.71e-2)" "unprognostic (8.58e-2)" "unprognostic (9.20e-3)" "unprognostic (2.28e-2)" "unprognostic (7.50e-3)" "unprognostic (6.48e-2)" "unprognostic (4.20e-1)" "unprognostic (1.24e-1)" "unprognostic (3.12e-2)" "unprognostic (5.84e-2)" "unprognostic (3.31e-1)" "unprognostic (5.37e-2)" "unprognostic (6.51e-2)" RRP1B "KIAA0179, Nnp1, PPP1R136, RRP1" ENSG00000160208 "Ribosomal RNA processing 1B" Q14684 21 43659560-43696079 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, mRNA processing, mRNA splicing, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 186.3;Early spermatids: 370.8;Late spermatids: 583.7;Rod photoreceptor cells: 306.3" "Group enriched" "Detected in all" 7 "Neuronal cells: 306.3;Spermatogenic cell types: 583.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 11018832.7;T-cells: 11431486.4" "Group enriched" "Detected in many" "intestine: 2101944.3;Stomach: 1118321.0" "HPA017893, HPA020324" Supported Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No 9100 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 79: Photoreceptor cells - Phototransduction" 59 "Nucleoli, Nucleoli rim, Mitotic chromosome" Nucleoplasm "HPA017893: , HPA020324: " "unprognostic (3.87e-2)" "unprognostic (1.64e-2)" "unprognostic (6.19e-2)" "unprognostic (4.86e-3)" "unprognostic (1.40e-1)" "unprognostic (6.16e-2)" "unprognostic (3.80e-2)" "unprognostic (5.67e-3)" "unprognostic (1.36e-1)" "unprognostic (1.77e-2)" "potential prognostic favorable (1.71e-4)" "unprognostic (1.71e-1)" "unprognostic (1.08e-2)" "unprognostic (8.21e-3)" "unprognostic (1.88e-3)" "unprognostic (2.63e-3)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (6.42e-2)" "unprognostic (1.08e-1)" "unprognostic (1.86e-2)" "unprognostic (5.28e-2)" "unprognostic (7.18e-2)" "unprognostic (1.40e-1)" "unprognostic (2.56e-2)" "unprognostic (1.76e-2)" "unprognostic (3.82e-2)" "unprognostic (1.67e-1)" "unprognostic (2.47e-1)" "unprognostic (2.92e-1)" "unprognostic (1.17e-3)" "unprognostic (1.67e-1)" RRP36 "C6orf153, dJ20C7.4" ENSG00000124541 "Ribosomal RNA processing 36" Q96EU6 6 43021623-43034156 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 117.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 821276.6;Neurons: 789024.4;T-cells: 1411728.7" "Tissue enriched" "Detected in single" 48 "lymphoid tissue: 4847.0" "HPA029904, HPA029905" Uncertain Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 4 "Nucleoplasm, Nucleoli" "HPA029904: , HPA029905: " "unprognostic (1.38e-2)" "unprognostic (1.36e-2)" "unprognostic (8.37e-2)" "unprognostic (1.36e-1)" "unprognostic (3.55e-1)" "unprognostic (3.51e-1)" "unprognostic (8.34e-2)" "unprognostic (3.63e-2)" "potential prognostic unfavorable (6.22e-5)" "unprognostic (9.76e-3)" "unprognostic (7.82e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (4.98e-5)" "unprognostic (1.10e-3)" "unprognostic (4.48e-3)" "unprognostic (9.35e-3)" "unprognostic (8.41e-2)" "unprognostic (4.93e-2)" "unprognostic (8.41e-3)" "unprognostic (2.05e-1)" "unprognostic (4.65e-2)" "unprognostic (8.45e-2)" "unprognostic (3.33e-1)" "unprognostic (6.68e-2)" "unprognostic (3.22e-1)" "unprognostic (5.77e-2)" "unprognostic (1.03e-1)" "unprognostic (3.00e-1)" "unprognostic (1.27e-3)" "unprognostic (8.26e-2)" RRP8 "KIAA0409, NML" ENSG00000132275 "Ribosomal RNA processing 8" O43159 11 6595072-6603616 "Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 823416.6" "HPA038487, HPA057562" Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 17: Non-specific - RNA processing" 83 "Nucleoplasm, Nucleoli, Cytosol" "HPA038487: , HPA057562: " "unprognostic (8.27e-3)" "unprognostic (7.46e-2)" "unprognostic (2.90e-1)" "unprognostic (1.08e-2)" "unprognostic (8.21e-2)" "unprognostic (1.92e-1)" "unprognostic (1.23e-1)" "unprognostic (7.04e-2)" "unprognostic (4.17e-2)" "unprognostic (7.64e-2)" "potential prognostic unfavorable (4.29e-5)" "unprognostic (1.83e-2)" "unprognostic (1.45e-2)" "unprognostic (1.98e-3)" "unprognostic (1.09e-1)" "unprognostic (1.31e-1)" "potential prognostic unfavorable (4.79e-4)" "unprognostic (1.97e-1)" "unprognostic (6.26e-2)" "unprognostic (6.45e-2)" "unprognostic (2.63e-2)" "unprognostic (2.72e-1)" "unprognostic (1.18e-1)" "unprognostic (2.84e-2)" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (2.14e-1)" "unprognostic (9.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.90e-1)" "unprognostic (4.41e-2)" RSC1A1 RS1 ENSG00000215695 "Regulator of solute carriers 1" Q92681 1 15659713-15662033 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 1.5;Microglia: 1.3" "Cell type enhanced" "Detected in some" "Ciliated cells: 1.5;Glial cells: 1.3" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in some" "Stomach Adenocarcinoma (TCGA): 3.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 247 "Capillaries: 29348.4;Cardiomyocytes: 11897.0;Skeletal myofibers: 32751.5" "Tissue enriched" "Detected in single" 1758 "heart muscle: 175831.2" "HPA027813, HPA028676" Approved Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Basal body" NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 22: Non-specific - Basic cellular functions" 3 "Golgi apparatus, Vesicles, Plasma membrane" "Nucleoplasm, Nuclear bodies, Primary cilium, Primary cilium tip, Basal body" "HPA027813: , HPA028676: " "unprognostic (4.48e-1)" "unprognostic (4.54e-2)" "unprognostic (6.22e-2)" "unprognostic (3.24e-1)" "unprognostic (1.08e-2)" "unprognostic (1.63e-1)" "unprognostic (1.88e-2)" "unprognostic (9.25e-2)" "unprognostic (3.46e-2)" "unprognostic (1.89e-2)" "unprognostic (1.75e-1)" "potential prognostic favorable (7.50e-4)" "unprognostic (9.29e-2)" "unprognostic (7.62e-1)" RSL1D1 "CSIG, DKFZP564M182, L12, PBK1, UTP30" ENSG00000171490 "Ribosomal L1 domain containing 1" O76021 16 11833850-11851580 "Essential proteins, Predicted intracellular proteins, Ribosomal proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA043483 Supported Approved "Nucleoli rim,Mitotic chromosome,Vesicles,Primary cilium" Yes No 400000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 15: Non-specific - Protein processing" 106 "Nucleoli rim, Mitotic chromosome" "Vesicles, Primary cilium" "HPA043483: " "unprognostic (4.69e-3)" "unprognostic (7.03e-3)" "unprognostic (1.67e-1)" "unprognostic (7.52e-2)" "unprognostic (2.11e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-1)" "unprognostic (1.88e-1)" "unprognostic (2.01e-2)" "unprognostic (6.78e-2)" "potential prognostic favorable (3.68e-7)" "unprognostic (2.61e-2)" "unprognostic (1.43e-3)" "unprognostic (1.32e-2)" "unprognostic (5.49e-3)" "unprognostic (7.94e-2)" "unprognostic (1.29e-3)" "unprognostic (2.25e-1)" "unprognostic (8.60e-2)" "unprognostic (6.52e-2)" "unprognostic (2.96e-2)" "unprognostic (4.72e-3)" "unprognostic (2.27e-2)" "unprognostic (1.04e-1)" "potential prognostic favorable (5.20e-4)" "unprognostic (3.44e-1)" "unprognostic (1.94e-1)" "unprognostic (2.56e-2)" "unprognostic (1.55e-1)" "unprognostic (5.41e-3)" "potential prognostic favorable (6.18e-4)" RSPH10B ENSG00000155026 "Radial spoke head 10 homolog B" P0C881 7 5925550-5970689 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "fallopian tube: 7.9;testis: 18.2" "Cell type enriched" "Detected in some" 4 "Late spermatids: 236.3" "Cell type enriched" "Detected in some" 7 "Spermatogenic cell types: 236.3" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 3.4;ependymal cell: 7.8" "Group enriched" "Detected in some" 8 "Prostate Adenocarcinoma (TCGA): 4.1;Testicular Germ Cell Tumor (TCGA): 2.6;Uterine Corpus Endometrial Carcinoma (TCGA): 5.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA049182 Supported Approved "Plasma membrane,Microtubules,Primary cilium,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 67: Non-specific - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "Primary cilium" "Plasma membrane, Microtubules, Cytosol" "HPA049182: " "unprognostic (1.15e-2)" "unprognostic (1.86e-2)" "unprognostic (2.15e-1)" "unprognostic (1.35e-1)" RSPH10B2 ENSG00000169402 "Radial spoke head 10 homolog B2" B2RC85 7 6754103-6799365 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 9.5;testis: 18.2" "Cell type enhanced" "Detected in some" "Early spermatids: 29.3;Endometrial ciliated cells: 11.0;Ependymal cells: 29.3;Epicardial cells: 9.1;Epididymal efferent duct ciliated cells: 9.2;Fallopian tube ciliated cells: 21.9;Late primary spermatocytes: 23.2;Late spermatids: 113.0;Respiratory ciliated cells: 24.6" "Group enriched" "Detected in some" 7 "Ciliated cells: 29.3;Spermatogenic cell types: 113.0" "Cell type enriched" "Detected in many" 9 "ependymal cell: 27.6" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA049182 Supported Approved "Plasma membrane,Microtubules,Primary cilium,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Primary cilium" "Plasma membrane, Microtubules, Cytosol" "HPA049182: " "unprognostic (1.65e-1)" "unprognostic (7.09e-3)" "unprognostic (1.42e-1)" RSPH3 "dJ111C20.1, RSHL2, RSP3" ENSG00000130363 "Radial spoke head 3" 6 158972871-159000202 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 160.5;Endometrial ciliated cells: 206.2;Ependymal cells: 176.0;Esophageal apical cells: 187.5;Respiratory ciliated cells: 313.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 187.5;Ciliated cells: 313.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039109 Approved Approved "Plasma membrane,Cytosol,Flagellar centriole,Mid piece,Annulus" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Plasma membrane, Flagellar centriole, Mid piece, Annulus" Cytosol "HPA039109: " "unprognostic (2.29e-1)" "unprognostic (2.48e-3)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (7.34e-5)" "unprognostic (1.32e-1)" "unprognostic (5.88e-2)" "unprognostic (1.88e-1)" "unprognostic (3.29e-2)" "unprognostic (3.48e-2)" "unprognostic (1.51e-3)" "potential prognostic favorable (3.26e-6)" "unprognostic (8.15e-3)" "unprognostic (4.15e-2)" "unprognostic (1.40e-3)" "unprognostic (1.72e-1)" "unprognostic (6.30e-2)" "unprognostic (6.84e-2)" "unprognostic (2.12e-1)" "unprognostic (9.56e-2)" "unprognostic (1.76e-2)" "unprognostic (2.60e-2)" "unprognostic (5.24e-2)" "unprognostic (8.72e-3)" "unprognostic (2.63e-1)" "unprognostic (3.48e-2)" "unprognostic (4.87e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "unprognostic (2.29e-1)" "unprognostic (8.38e-2)" "unprognostic (2.00e-1)" RSPH4A "CILD11, dJ412I7.1, FLJ37974, RSHL3, RSPH6B" ENSG00000111834 "Radial spoke head component 4A" Q5TD94 6 116616479-116632985 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 22.0;fallopian tube: 35.0" "Group enriched" "Detected in many" 4 "Endometrial ciliated cells: 109.3;Ependymal cells: 90.6;Epididymal efferent duct ciliated cells: 93.2;Fallopian tube ciliated cells: 263.2;Respiratory ciliated cells: 317.0" "Cell type enriched" "Detected in many" 8 "Ciliated cells: 317.0" "Group enriched" "Detected in many" 16 "choroid plexus epithelial cell: 26.2;ependymal cell: 102.9" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 6.7" "Region enhanced" "Detected in all" "choroid plexus: 46.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 19.3" "Cell type enriched" "Detected in single" 248709 "Fallopian tube cells: 24870931.1" "Tissue enriched" "Detected in single" 218962 "fallopian tube: 21896157.5" "HPA031196, HPA031197, HPA031198" Enhanced Approved "Connecting piece,Flagellar centriole,Annulus" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" "Connecting piece, Flagellar centriole" Annulus "HPA031196: , HPA031197: , HPA031198: " "unprognostic (1.10e-1)" "unprognostic (1.58e-1)" "unprognostic (1.71e-1)" "unprognostic (3.08e-3)" "unprognostic (4.40e-2)" "unprognostic (3.11e-1)" "unprognostic (2.12e-1)" "unprognostic (3.27e-1)" "unprognostic (2.12e-2)" "unprognostic (2.78e-1)" "unprognostic (1.97e-1)" RSRC2 FLJ11021 ENSG00000111011 "Arginine and serine rich coiled-coil 2" Q7L4I2 12 122503454-122527000 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 6703779.7;Neurons: 4582645.5" "Tissue enhanced" "Detected in many" "salivary gland: 29480926.2" "HPA040070, HPA048183" Enhanced Approved "Nucleoli fibrillar center,Nuclear speckles,Cytosol" No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 15: Bone marrow - Innate immune response" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 38: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 9 "Nuclear speckles" "Nucleoli fibrillar center, Cytosol" "HPA040070: , HPA048183: " "unprognostic (3.13e-1)" "unprognostic (7.68e-2)" "unprognostic (1.95e-1)" "unprognostic (8.37e-2)" "unprognostic (4.29e-2)" "unprognostic (1.56e-1)" "unprognostic (1.71e-1)" "unprognostic (1.66e-2)" "unprognostic (1.08e-1)" "unprognostic (1.05e-2)" "potential prognostic favorable (1.20e-4)" "unprognostic (2.92e-3)" "unprognostic (9.02e-2)" "unprognostic (7.02e-3)" "unprognostic (1.02e-1)" "unprognostic (8.14e-2)" "unprognostic (5.90e-2)" "unprognostic (1.24e-1)" "unprognostic (5.28e-2)" "unprognostic (7.03e-2)" "unprognostic (3.46e-2)" "unprognostic (1.26e-2)" "unprognostic (2.16e-2)" "unprognostic (6.76e-2)" "unprognostic (1.82e-1)" "unprognostic (2.62e-1)" "unprognostic (1.18e-1)" "unprognostic (3.93e-2)" "unprognostic (2.66e-1)" "unprognostic (6.79e-2)" "unprognostic (2.78e-2)" RTCA "RPC, RTC1, RTCD1" ENSG00000137996 "RNA 3'-terminal phosphate cyclase" O00442 1 100266216-100292769 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 179.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA027982, HPA027990, HPA028151, HPA028331" Uncertain Enhanced Nucleoplasm NA NA 18000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 34: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 8: Non-specific - Secretory pathway" 1 Nucleoplasm "HPA027982: , HPA027990: , HPA028151: , HPA028331: " "unprognostic (1.21e-1)" "unprognostic (1.57e-2)" "unprognostic (2.55e-2)" "unprognostic (7.21e-3)" "unprognostic (1.01e-2)" "unprognostic (6.00e-2)" "unprognostic (1.89e-1)" "unprognostic (3.11e-3)" "potential prognostic unfavorable (9.06e-6)" "potential prognostic favorable (3.90e-5)" "unprognostic (6.40e-2)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (4.07e-6)" "potential prognostic unfavorable (1.82e-4)" "unprognostic (1.28e-1)" "unprognostic (1.22e-1)" "unprognostic (3.22e-2)" "unprognostic (2.04e-1)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" "unprognostic (1.00e-2)" "unprognostic (2.28e-1)" "unprognostic (2.28e-2)" "unprognostic (7.47e-2)" "unprognostic (1.82e-1)" "unprognostic (5.06e-2)" "unprognostic (5.09e-2)" "unprognostic (4.03e-2)" "unprognostic (4.06e-1)" RTKN B5 ENSG00000114993 Rhotekin Q9BST9 2 74425835-74442422 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 114.0;liver: 120.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 85.2;Proximal tubule cells: 76.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "committed oligodendrocyte precursor: 93.9;oligodendrocyte: 85.9;oligodendrocyte precursor cell: 82.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "NK-cell: 2.3;plasmacytoid DC: 6.5" "Group enriched" "Detected in many" 4 "dendritic cells: 6.5;NK-cells: 2.3" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 8293448.1;Proximal tubules: 13576178.3" "Tissue enriched" "Detected in many" "intestine: 484479.1" HPA030259 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 65: Non-specific - Cell growth & division" 14 Mitochondria Nucleoplasm "HPA030259: " "unprognostic (1.70e-1)" "unprognostic (8.36e-2)" "unprognostic (5.12e-2)" "unprognostic (4.88e-3)" "unprognostic (8.11e-2)" "unprognostic (4.54e-1)" "unprognostic (3.84e-2)" "unprognostic (4.97e-3)" "potential prognostic unfavorable (7.55e-4)" "unprognostic (2.21e-2)" "unprognostic (4.75e-3)" "unprognostic (2.13e-1)" "unprognostic (1.93e-2)" "unprognostic (1.34e-2)" "unprognostic (3.84e-3)" "unprognostic (6.50e-3)" "unprognostic (1.07e-2)" "unprognostic (2.55e-1)" "unprognostic (1.21e-2)" "unprognostic (1.59e-1)" "unprognostic (1.04e-1)" "unprognostic (9.44e-2)" "unprognostic (2.47e-2)" "unprognostic (4.13e-2)" "unprognostic (2.75e-1)" "unprognostic (1.72e-1)" "unprognostic (6.09e-2)" "unprognostic (1.23e-1)" "unprognostic (4.78e-1)" "unprognostic (1.63e-1)" "unprognostic (1.53e-1)" RTL1 "HUR1, Mar1, MART1, PEG11, SIRH2" ENSG00000254656 "Retrotransposon Gag like 1" A6NKG5 14 100879753-100903722 "Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.5;brain: 4.2;placenta: 2.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 42.5;Fibro-adipogenic progenitors: 27.8;Fibroblasts: 22.2;Lactotrophs: 10.7;Medullary thymic epithelial cells: 21.6;Myosatellite cells: 79.6;Other brain neurons: 17.8;Retinal ganglion cells: 27.0;Salivary myoepithelial cells: 12.6;Somatotrophs: 21.9" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 42.5;Fibro-adipogenic progenitors: 27.8;Fibroblasts: 22.2;Neuronal cells: 27.0;Pituitary endocrine cells: 21.9;Secretory gland support: 21.6;Stem cells: 79.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Skin Cutaneous Melanoma (TCGA): 2.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 51.0" "Adrenal gland - Adrenal medulla cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Keratinocytes: 2360975.0;Smooth muscle cells: 2916978.8" "Not detected" "Not detected" "HPA066979, HPA077601" Enhanced Approved Cytosol No NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 1: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Cytosol "HPA066979: , HPA077601: " "unprognostic (4.52e-3)" "unprognostic (6.93e-3)" "unprognostic (5.65e-2)" RTL3 "FLJ38865, Mar3, Mart3, SIRH9, ZCCHC5, ZHC5" ENSG00000179300 "Retrotransposon Gag like 3" Q8N8U3 X 78656068-78659328 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "blood vessel: 1.5" "Cell type enhanced" "Detected in single" "Leydig cells: 1.0" "Cell type enhanced" "Detected in single" "Leydig cells: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Brain cancer: 1.2;liver cancer: 1.5" "Region enriched" "Detected in single" 9 "hippocampal formation: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051991, HPA053174, HPA075136" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 72: Neuronal - Signal transduction" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA051991: , HPA053174: , HPA075136: " RTN4 "ASY, KIAA0886, NOGO, NSP-CL" ENSG00000115310 "Reticulon 4" Q9NQC3 2 54972187-55112621 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Müller glia: 3824.3;Neutrophils: 2066.2" "Cell type enhanced" "Detected in all" "Glial cells: 3824.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 97.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Liver - Hepatocytes, Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB005388, HPA023977" Supported Enhanced "Endoplasmic reticulum" NA NA 2600000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 11: Muller glia cells - Retinal homeostasis" 147 "Endoplasmic reticulum" "CAB005388: , HPA023977: " "unprognostic (1.90e-1)" "unprognostic (1.65e-3)" "unprognostic (2.22e-1)" "unprognostic (6.23e-3)" "unprognostic (2.55e-1)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (5.02e-4)" "unprognostic (1.43e-2)" "potential prognostic unfavorable (7.30e-5)" "unprognostic (8.81e-2)" "potential prognostic favorable (1.22e-5)" "unprognostic (2.09e-1)" "unprognostic (5.12e-2)" "unprognostic (6.92e-2)" "unprognostic (3.67e-1)" "unprognostic (3.60e-3)" "unprognostic (1.80e-1)" "unprognostic (4.41e-2)" "unprognostic (6.46e-2)" "unprognostic (1.91e-1)" "unprognostic (1.55e-2)" "unprognostic (9.66e-3)" "unprognostic (3.76e-2)" "unprognostic (3.07e-1)" "unprognostic (3.35e-1)" "unprognostic (1.37e-1)" "unprognostic (1.30e-1)" "unprognostic (2.76e-2)" "unprognostic (1.67e-1)" "unprognostic (2.63e-1)" "unprognostic (1.50e-1)" RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8" "Group enriched" "Detected in many" 5 "Early spermatids: 432.8;Late spermatids: 1254.8" "Cell type enriched" "Detected in many" 7 "Spermatogenic cell types: 1254.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Breast Invasive Carcinoma (TCGA): 12.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 8.7" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 1396420.8;Microglia and Neuropil: 963316.9;Neurons: 710696.4" "Tissue enriched" "Detected in single" 126959 "cerebral cortex: 12695897.1" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Receptor Yes NA 19000 "Cluster 2: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 5 "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: " "unprognostic (8.26e-2)" "unprognostic (1.24e-1)" "unprognostic (3.56e-1)" "unprognostic (6.15e-3)" "unprognostic (3.66e-2)" "unprognostic (2.37e-2)" "unprognostic (7.65e-2)" "unprognostic (1.82e-1)" "unprognostic (2.30e-3)" "unprognostic (6.08e-3)" "unprognostic (1.89e-2)" "unprognostic (4.11e-2)" "unprognostic (3.49e-2)" "unprognostic (1.80e-3)" "unprognostic (7.04e-3)" "unprognostic (5.20e-2)" "unprognostic (3.01e-2)" "unprognostic (4.20e-2)" "unprognostic (2.11e-2)" RTTN DKFZP434G145 ENSG00000176225 Rotatin Q86VV8 18 70003031-70205726 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 4 "Microglia: 746.1" "Cell type enriched" "Detected in all" 4 "Glial cells: 746.1" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 849.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 355556.1;Granulosa cells: 263137.8" "Not detected" "Not detected" "HPA041343, HPA041967, HPA075089" Uncertain Uncertain "Centrosome,Basal body,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 1 Cytosol "Centrosome, Basal body" "HPA041343: , HPA041967: , HPA075089: " "unprognostic (1.36e-3)" "unprognostic (3.22e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-2)" "unprognostic (6.67e-2)" "unprognostic (5.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.48e-3)" "unprognostic (1.47e-3)" "unprognostic (1.96e-1)" "potential prognostic favorable (5.78e-4)" "unprognostic (1.49e-1)" "unprognostic (9.81e-2)" "unprognostic (5.08e-2)" "unprognostic (4.90e-2)" "unprognostic (6.65e-3)" "unprognostic (2.23e-1)" "unprognostic (5.60e-2)" "unprognostic (1.22e-1)" "unprognostic (2.58e-1)" "unprognostic (9.41e-3)" "unprognostic (1.36e-1)" "unprognostic (1.52e-1)" "unprognostic (9.77e-2)" "unprognostic (3.56e-1)" "unprognostic (4.72e-2)" "unprognostic (1.57e-1)" "unprognostic (3.13e-1)" RUNDC1 DKFZp761H0421 ENSG00000198863 "RUN domain containing 1" Q96C34 17 42980565-42995142 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 99.9;Fallopian tube ciliated cells: 70.4" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 99.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 315690.5" "Tissue enhanced" "Detected in many" "lymphoid tissue: 467603.5" HPA023726 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" "Nuclear speckles" Cytosol "HPA023726: " "unprognostic (3.79e-2)" "unprognostic (3.37e-1)" "unprognostic (2.08e-1)" "unprognostic (2.51e-2)" "unprognostic (4.14e-2)" "unprognostic (1.60e-1)" "unprognostic (1.19e-1)" "unprognostic (3.49e-1)" "unprognostic (2.25e-1)" "unprognostic (1.08e-3)" "potential prognostic favorable (1.01e-4)" "unprognostic (2.35e-3)" "unprognostic (5.52e-2)" "unprognostic (4.89e-2)" "unprognostic (5.44e-3)" "unprognostic (2.01e-1)" "unprognostic (1.54e-1)" "unprognostic (2.25e-1)" "unprognostic (9.68e-3)" "unprognostic (7.57e-2)" "unprognostic (6.57e-3)" "unprognostic (3.13e-3)" "unprognostic (1.88e-1)" "unprognostic (1.87e-1)" "unprognostic (1.07e-2)" "unprognostic (2.51e-1)" "unprognostic (9.48e-2)" "unprognostic (7.00e-2)" "unprognostic (2.06e-1)" "unprognostic (1.46e-1)" "unprognostic (7.33e-2)" RUNDC3A "RAP2IP, RPIP8" ENSG00000108309 "RUN domain containing 3A" Q59EK9 17 44308413-44318670 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 297.6;pituitary gland: 94.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Brain excitatory neurons: 62.5;Brain inhibitory neurons: 42.7;Corticotrophs: 33.6;Early spermatids: 27.4;Erythrocytes: 49.1;Gonadotrophs: 26.8;Lactotrophs: 26.1;Late spermatids: 150.0;Neuroendocrine cells: 29.8;Other brain neurons: 47.9;Pancreatic islet cells: 33.1;Retinal amacrine cells: 24.9;Retinal bipolar cells: 29.5;Somatotrophs: 33.0;Thyrotrophs: 23.0" "Cell type enhanced" "Detected in many" "Erythrocytes: 49.1;Neuronal cells: 62.5;Spermatogenic cell types: 150.0" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 28.8;Pancreatic Adenocarcinoma (TCGA): 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "lung cancer: 12.2;Neuroblastoma: 48.1" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Skin - Keratinocyte (granular), Spleen - Erythrocytes, Stomach - Gastric enteroendocrine cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 7031731.1;Microglia and Neuropil: 9575605.0;Neurons: 17335108.9" "Tissue enhanced" "Detected in some" "cerebral cortex: 2405737.7;skin: 3087583.8" "HPA023548, HPA070733" Enhanced Supported Enhanced Vesicles NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 24 Vesicles "HPA023548: , HPA070733: " "unprognostic (1.86e-1)" "unprognostic (6.14e-2)" "unprognostic (3.99e-2)" "unprognostic (7.61e-2)" "unprognostic (2.24e-1)" "unprognostic (2.84e-1)" "potential prognostic favorable (6.97e-4)" "unprognostic (6.98e-2)" "unprognostic (1.53e-2)" "unprognostic (3.53e-3)" "unprognostic (4.85e-2)" "unprognostic (9.11e-2)" "unprognostic (1.91e-1)" "unprognostic (3.58e-2)" "unprognostic (1.01e-1)" "unprognostic (5.73e-3)" "unprognostic (6.47e-2)" "potential prognostic favorable (5.27e-4)" "unprognostic (2.06e-3)" "unprognostic (1.70e-1)" "unprognostic (9.64e-3)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (2.13e-2)" RUNDC3B "RPIB9, RPIP9" ENSG00000105784 "RUN domain containing 3B" Q96NL0 7 87627548-87832296 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 7.8;brain: 5.0;liver: 5.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 376.3;Brain excitatory neurons: 205.9;Brain inhibitory neurons: 228.1;Enterocytes: 88.5;Gonadotrophs: 110.9;Hematopoietic stem cells: 165.9;Other brain neurons: 188.1;Retinal amacrine cells: 97.6;Retinal ganglion cells: 220.2;Vascular endothelial cells: 145.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 376.3;Endothelial cells: 145.9;Neuronal cells: 228.1;Stem cells: 165.9" "Cell type enhanced" "Detected in all" "endothelial cell: 991.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Neuroblastoma: 1.8" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Endothelial cells, Stomach - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 1379576.2;Microglia and Neuropil: 2688256.0;Neurons: 773616.6" "Tissue enriched" "Detected in single" 318 "cerebral cortex: 31817.3" "HPA056968, HPA057155" Uncertain Approved "Intermediate filaments,Cytokinetic bridge,Primary cilium,Centrosome,Basal body,Cytosol" Yes NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 104: Brain endothelial cells - Blood brain barrier" 4 "Intermediate filaments" "Cytokinetic bridge, Primary cilium, Centrosome, Basal body, Cytosol" "HPA056968: , HPA057155: " "unprognostic (1.38e-1)" "unprognostic (9.04e-2)" "potential prognostic favorable (9.71e-4)" "potential prognostic favorable (9.17e-6)" RUNX1 "AML1, AMLCR1, CBFA2, PEBP2A2" ENSG00000159216 "RUNX family transcription factor 1" Q01196 21 34787801-36004667 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 42.9" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 1602.7;Megakaryocyte progenitors: 1572.8;Megakaryocyte-Erythroid progenitors: 1466.1;Neutrophil progenitors: 1514.5;Salivary basal cells: 1411.7;Salivary duct cells: 1811.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 14 "central nervous system macrophage: 1198.3;leukocyte: 976.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 24.0" "Lineage enriched" "Detected in all" 5 "granulocytes: 24.0" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neutrophils: 3814655.9" "Group enriched" "Detected in some" 29597 "bone marrow: 2815315.0;lymphoid tissue: 3104012.5" "HPA004176, HPA037912" Enhanced Enhanced Nucleoplasm,Vesicles No No "Cluster 22: Eosinophils - Transcription" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 58 Nucleoplasm Vesicles "HPA004176: , HPA037912: " "unprognostic (1.32e-3)" "unprognostic (1.35e-2)" "unprognostic (2.33e-1)" "unprognostic (5.10e-3)" "unprognostic (2.52e-2)" "unprognostic (1.19e-2)" "unprognostic (1.39e-2)" "unprognostic (1.30e-2)" "unprognostic (2.70e-2)" "unprognostic (2.53e-2)" "potential prognostic unfavorable (7.51e-8)" "unprognostic (8.32e-3)" "unprognostic (3.61e-2)" "unprognostic (1.32e-1)" "unprognostic (1.52e-1)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (3.58e-1)" "unprognostic (1.57e-1)" "unprognostic (4.75e-3)" "unprognostic (1.70e-2)" "unprognostic (1.18e-2)" "unprognostic (2.32e-2)" "unprognostic (7.78e-2)" "unprognostic (2.64e-1)" "unprognostic (2.39e-2)" "unprognostic (9.91e-2)" "unprognostic (8.50e-2)" "unprognostic (3.67e-1)" "unprognostic (6.66e-2)" "unprognostic (1.54e-1)" RUNX2 "AML3, CBFA1, CCD, CCD1, PEBP2A1, PEBP2aA1" ENSG00000124813 "RUNX family transcription factor 2" Q13950 6 45328157-45664349 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" DNA-binding "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 374.3;Innate lymphoid cells: 924.4;Late spermatids: 390.5;Microglia: 449.9;pDCs: 868.3;Salivary duct cells: 518.3;Salivary ionocytes: 723.4;Thymocytes: 695.3" "Cell type enhanced" "Detected in many" "dendritic cells: 868.3;Innate lymphoid cells: 924.4;Ionocytes: 723.4;T-cells: 695.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 573.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 22.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 29.5" "Skin - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Neutrophils: 98345.7;T-cells: 259439.1" "Tissue enriched" "Detected in single" 2219 "lymphoid tissue: 221930.5" "CAB008374, HPA022040, CAB062561, CAB068226, HPA070715" Enhanced Enhanced Nucleoplasm No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 72: Neuronal - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 32 Nucleoplasm "CAB008374: , CAB062561: , CAB068226: , HPA022040: , HPA070715: " "unprognostic (2.74e-1)" "unprognostic (9.56e-2)" "unprognostic (1.02e-1)" "unprognostic (1.09e-1)" "unprognostic (1.34e-2)" "unprognostic (4.25e-2)" "unprognostic (3.54e-2)" "unprognostic (2.60e-1)" "unprognostic (4.92e-2)" "potential prognostic unfavorable (3.38e-4)" "validated prognostic unfavorable (6.17e-5)" "validated prognostic unfavorable (1.61e-4)" "unprognostic (2.52e-1)" "unprognostic (4.06e-2)" "unprognostic (1.58e-2)" "unprognostic (4.06e-2)" "unprognostic (1.04e-1)" "unprognostic (2.96e-2)" "unprognostic (1.46e-2)" "unprognostic (4.10e-3)" "unprognostic (1.58e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-1)" "unprognostic (3.81e-3)" "unprognostic (2.36e-1)" "unprognostic (2.89e-1)" "unprognostic (3.76e-3)" "unprognostic (3.29e-2)" "unprognostic (9.05e-2)" "unprognostic (3.84e-2)" RUSF1 "C16orf58, FLJ13868" ENSG00000140688 "RUS family member 1" Q96GQ5 16 31489471-31509309 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA024406 Uncertain Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 14: Neurons - Synaptic function" "Cluster 54: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 77 "Nucleoli, Golgi apparatus, Vesicles" "Nucleoplasm, Cytosol" "HPA024406: " "unprognostic (3.28e-2)" "unprognostic (1.30e-3)" "unprognostic (3.24e-2)" "unprognostic (1.32e-1)" "unprognostic (1.79e-2)" "unprognostic (2.50e-2)" "unprognostic (8.73e-2)" "unprognostic (6.91e-3)" "unprognostic (2.31e-1)" "potential prognostic favorable (1.95e-4)" "unprognostic (2.47e-1)" "unprognostic (3.07e-1)" "unprognostic (1.15e-1)" "unprognostic (8.90e-2)" "unprognostic (2.62e-1)" "unprognostic (6.72e-2)" "unprognostic (2.61e-2)" "unprognostic (1.39e-1)" "unprognostic (8.13e-2)" "unprognostic (2.80e-2)" "unprognostic (6.32e-2)" "unprognostic (1.65e-1)" "unprognostic (3.31e-2)" "unprognostic (5.92e-2)" "unprognostic (8.35e-2)" "unprognostic (2.36e-1)" "unprognostic (1.65e-1)" "unprognostic (2.34e-1)" "unprognostic (3.58e-2)" RUVBL1 "ECP54, INO80H, NMP238, Pontin52, RVB1, TIH1, TIP49, TIP49a" ENSG00000175792 "RuvB like AAA ATPase 1" Q9Y265 3 128064778-128153914 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA recombination, DNA repair, Growth regulation, Mitosis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epicardial cells: 325.2;Fallopian tube ciliated cells: 274.6;Respiratory ciliated cells: 272.9" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 325.2;Ciliated cells: 274.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fallopian tube cells: 156457154.0" "Tissue enhanced" "Detected in all" "fallopian tube: 90922359.2" "HPA019947, HPA019948" Enhanced Supported "Nucleoplasm,Nuclear speckles,Basal body,Cytosol" NA NA 210000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 3: Choroid plexus - Cilium" "Cluster 63: Non-specific - Protein processing" "Cluster 107: Ciliated cells - Cilia assembly & function" 265 "Nucleoplasm, Nuclear speckles" "Basal body, Cytosol" "HPA019947: , HPA019948: " "unprognostic (3.23e-2)" "unprognostic (7.66e-2)" "unprognostic (9.62e-2)" "unprognostic (2.10e-1)" "unprognostic (8.89e-3)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.51e-2)" "unprognostic (2.06e-2)" "unprognostic (5.45e-3)" "unprognostic (1.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.23e-2)" "validated prognostic unfavorable (6.86e-10)" "validated prognostic unfavorable (5.43e-4)" "unprognostic (1.17e-2)" "unprognostic (4.33e-3)" "unprognostic (2.54e-1)" "unprognostic (2.24e-1)" "unprognostic (2.32e-2)" "unprognostic (1.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.04e-1)" "unprognostic (1.79e-2)" "unprognostic (4.77e-2)" "unprognostic (4.38e-2)" "unprognostic (1.46e-2)" "unprognostic (1.79e-1)" "unprognostic (3.72e-1)" "unprognostic (8.20e-2)" "unprognostic (1.40e-1)" RUVBL2 "ECP51, INO80J, Reptin52, RVB2, TIH2, TIP48, TIP49b" ENSG00000183207 "RuvB like AAA ATPase 2" Q9Y230 19 48993562-49015970 "Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Growth regulation, Transcription, Transcription regulation" "Activator, Chromatin regulator, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 232.1" "Cell type enhanced" "Detected in many" "Early spermatids: 588.2;Fallopian tube ciliated cells: 300.7;Late primary spermatocytes: 918.0;Late spermatids: 1436.5;Respiratory ciliated cells: 275.8" "Cell type enriched" "Detected in all" 4 "Spermatogenic cell types: 1436.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Fallopian tube cells: 201058061.6" "Tissue enhanced" "Detected in all" "fallopian tube: 93976728.3" "CAB012432, HPA042880, HPA067966" Enhanced Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA 150000 "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 21: Non-specific - Metabolism" "Cluster 4: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 356 "Nucleoplasm, Cytosol" "Centrosome, Basal body" "CAB012432: , HPA042880: , HPA067966: " "unprognostic (1.96e-2)" "unprognostic (1.41e-1)" "unprognostic (4.43e-3)" "unprognostic (1.54e-2)" "unprognostic (2.01e-2)" "unprognostic (2.69e-1)" "unprognostic (2.53e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (7.55e-4)" "unprognostic (7.23e-2)" "unprognostic (1.43e-1)" "unprognostic (1.34e-1)" "unprognostic (9.68e-3)" "validated prognostic unfavorable (1.58e-6)" "validated prognostic unfavorable (4.22e-4)" "potential prognostic unfavorable (1.24e-5)" "unprognostic (5.60e-2)" "unprognostic (8.33e-2)" "unprognostic (1.48e-1)" "unprognostic (7.01e-2)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (2.86e-1)" "unprognostic (8.21e-2)" "unprognostic (8.24e-2)" "unprognostic (9.94e-2)" "unprognostic (6.27e-2)" "unprognostic (3.33e-1)" "unprognostic (4.68e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-1)" RWDD2A "dJ747H23.2, MGC13523, RWDD2" ENSG00000013392 "RWD domain containing 2A" Q9UIY3 6 83193357-83198935 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.2;Late primary spermatocytes: 128.8;Prostatic glandular cells: 44.2;Retinal pigment epithelial cells: 25.6" "Cell type enhanced" "Detected in many" "Glandular cells: 44.2;Spermatogenic cell types: 128.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 16.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 1373147.1;Neurons: 4015183.7" "Tissue enriched" "Detected in single" 22874 "cerebral cortex: 2287371.3" "HPA030105, HPA030106, HPA030107" Uncertain Approved Vesicles NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 60: Prostate cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 Vesicles "HPA030105: , HPA030106: , HPA030107: " "unprognostic (1.51e-1)" "unprognostic (1.93e-3)" "unprognostic (2.30e-1)" "unprognostic (3.60e-2)" "unprognostic (1.27e-1)" "unprognostic (2.43e-1)" "unprognostic (2.75e-2)" "unprognostic (1.67e-2)" "unprognostic (2.39e-2)" "unprognostic (1.25e-2)" "unprognostic (6.88e-3)" "potential prognostic favorable (7.27e-5)" "unprognostic (2.42e-2)" "unprognostic (4.19e-2)" "unprognostic (6.86e-2)" "unprognostic (2.38e-2)" "unprognostic (1.92e-1)" "unprognostic (2.98e-1)" "unprognostic (9.20e-3)" "potential prognostic favorable (8.83e-4)" "unprognostic (6.68e-2)" "potential prognostic favorable (2.27e-5)" "unprognostic (8.29e-2)" "unprognostic (3.00e-2)" "potential prognostic favorable (2.98e-4)" "unprognostic (2.07e-1)" "unprognostic (1.85e-1)" "unprognostic (4.58e-2)" "unprognostic (6.72e-2)" "unprognostic (4.03e-3)" "unprognostic (2.97e-2)" RXRB "H-2RIIBP, NR2B2, RCoR-1, RXR-beta, RXRbeta" ENSG00000204231 "Retinoid X receptor beta" P28702 6 33193588-33200665 "Cancer-related genes, FDA approved drug targets, Nuclear receptors, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 16.5;Bergmann glia: 19.2;Brain excitatory neurons: 17.7;Brain inhibitory neurons: 17.1;Choroid plexus epithelial cells: 9.0;Distal convoluted tubule cells: 12.1;Ependymal cells: 11.0;Loop of henle epithelial cells: 10.9;Microglia: 14.3;Oligodendrocyte progenitor cells: 16.7;Oligodendrocytes: 19.8;Other brain neurons: 16.1;Podocytes: 11.6;Proximal tubule cells: 15.9;Renal collecting duct intercalated cells: 11.8;Renal collecting duct principal cells: 9.4;Renal connecting tubule cells: 12.7" "Group enriched" "Detected in some" 4 "Ciliated cells: 11.0;Ductal cells: 12.7;Glial cells: 19.8;Neuronal cells: 17.7;Renal nephron cells: 15.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Keratinocytes: 9911179.9" "Group enriched" "Detected in many" "lung: 1441947.4;lymphoid tissue: 489293.0" "CAB002003, HPA071592, HPA075035" Supported Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 27 Nucleoplasm "Nucleoli, Cytosol" "CAB002003: , HPA071592: , HPA075035: " "unprognostic (2.84e-2)" "unprognostic (3.51e-1)" "unprognostic (1.91e-1)" "unprognostic (2.30e-1)" "unprognostic (3.82e-1)" "unprognostic (3.31e-1)" "unprognostic (2.01e-2)" "potential prognostic favorable (4.82e-4)" "unprognostic (1.68e-2)" "unprognostic (3.32e-1)" "unprognostic (3.83e-2)" "unprognostic (7.15e-2)" "unprognostic (1.58e-2)" "unprognostic (1.94e-1)" "unprognostic (2.14e-2)" "unprognostic (2.19e-1)" "unprognostic (3.21e-2)" "unprognostic (2.45e-1)" "unprognostic (3.81e-1)" "unprognostic (2.13e-1)" "unprognostic (3.82e-2)" "unprognostic (1.18e-2)" "unprognostic (1.79e-1)" "unprognostic (2.78e-1)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (1.01e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (9.84e-2)" "unprognostic (1.09e-1)" RYK "D3S3195, JTK5, JTK5A, RYK1" ENSG00000163785 "Receptor like tyrosine kinase" P34925 3 134065303-134250859 "Enzymes, Predicted membrane proteins" "Wnt signaling pathway" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB034117, HPA045503, HPA075430, CAB080389" Approved Approved "Golgi apparatus,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 7: Non-specific - Ribosome" "Cluster 63: Non-specific - Protein processing" "Cluster 7: Non-specific - Transcription" 36 "Golgi apparatus" Cytosol "CAB034117: , CAB080389: , HPA045503: , HPA075430: " "unprognostic (2.16e-1)" "unprognostic (8.96e-2)" "unprognostic (3.96e-2)" "unprognostic (3.59e-2)" "unprognostic (1.18e-1)" "unprognostic (1.60e-1)" "unprognostic (1.10e-1)" "unprognostic (6.92e-2)" "unprognostic (2.97e-1)" "unprognostic (1.41e-2)" "unprognostic (1.27e-2)" "unprognostic (7.74e-3)" "unprognostic (3.47e-2)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (2.77e-2)" "unprognostic (1.52e-1)" "unprognostic (5.12e-2)" "unprognostic (1.27e-1)" "unprognostic (3.91e-2)" "unprognostic (4.62e-1)" "unprognostic (7.91e-3)" "unprognostic (3.07e-3)" "unprognostic (8.04e-3)" "unprognostic (1.90e-1)" "unprognostic (2.99e-3)" "unprognostic (1.87e-1)" "unprognostic (1.04e-1)" "unprognostic (1.73e-1)" "unprognostic (1.84e-1)" "unprognostic (1.38e-1)" "unprognostic (1.48e-1)" S100A1 "S100-alpha, S100A" ENSG00000160678 "S100 calcium binding protein A1" P23297 1 153627926-153632039 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "brain: 1266.4;heart muscle: 2882.1;skeletal muscle: 2868.7;tongue: 4577.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 1751.0;Breast secretory cells: 341.5;Endometrial glandular cells: 202.0;Endometrial luminal cells: 163.6;Hofbauer cells: 449.1;Lacrimal acinar cells: 461.1;Melanocytes: 208.7;Salivary acinar cells: 470.7;Thymic myoid cells: 186.3" "Group enriched" "Detected in many" 4 "Acinar cells: 470.7;Mononuclear phagocytes: 449.1;Secretory cells: 1751.0" "Group enriched" "Detected in many" 5 "astrocyte: 91.3;committed oligodendrocyte precursor: 76.1;oligodendrocyte: 171.7" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 2441.2;Thyroid Carcinoma (TCGA): 1378.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Rhabdoid: 334.3;skin cancer: 729.5" "Heart muscle - Cardiomyocytes, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 13721031.6;Capillaries: 23920754.9;Cardiomyocytes: 52897382.4;Skeletal myofibers: 41844422.3" "Tissue enriched" "Detected in all" "heart muscle: 1173696631.1" "CAB002599, HPA006462" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 220000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 4: Breast lactating luminal cells - Lactation" 28 Cytosol "Nucleoplasm, Golgi apparatus" "CAB002599: , HPA006462: " "unprognostic (1.90e-1)" "unprognostic (3.11e-2)" "unprognostic (5.26e-2)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (7.83e-4)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "unprognostic (2.88e-2)" "unprognostic (4.23e-2)" "unprognostic (5.17e-3)" "unprognostic (2.39e-2)" "unprognostic (3.23e-2)" "unprognostic (7.68e-2)" "unprognostic (9.82e-2)" "unprognostic (7.70e-2)" "unprognostic (2.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.37e-2)" "unprognostic (2.24e-1)" "unprognostic (3.24e-1)" "unprognostic (1.45e-3)" "validated prognostic favorable (3.48e-4)" "validated prognostic favorable (1.15e-4)" "potential prognostic favorable (2.63e-4)" "unprognostic (4.81e-2)" "unprognostic (1.77e-2)" "unprognostic (4.78e-2)" "unprognostic (4.12e-2)" "unprognostic (1.29e-2)" "unprognostic (3.73e-3)" "unprognostic (8.73e-2)" S100A10 "42C, ANX2LG, CAL1L, CLP11, P11" ENSG00000197747 "S100 calcium binding protein A10" P60903 1 151982915-151993859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2017.3" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 40253.4" "Cell type enriched" "Detected in all" 4 "Apical squamous epithelial cells: 40253.4" "Cell type enhanced" "Detected in many" "endothelial cell: 193.8;ependymal cell: 115.9;leukocyte: 96.3;lower rhombic lip: 97.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 2009.9;monocytes: 1239.0;T-cells: 1183.5" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Kidney - Endothelial cells, Skeletal muscle - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 128702056.3" "Low tissue specificity" "Detected in all" "HPA003340, CAB025484" Enhanced Approved Mitochondria Yes No 640000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 29 Mitochondria "CAB025484: , HPA003340: " "unprognostic (4.73e-3)" "unprognostic (2.07e-1)" "unprognostic (4.15e-1)" "unprognostic (1.04e-3)" "unprognostic (5.01e-2)" "unprognostic (1.33e-1)" "unprognostic (2.42e-2)" "unprognostic (5.32e-3)" "unprognostic (5.12e-3)" "unprognostic (3.44e-2)" "unprognostic (1.26e-2)" "unprognostic (4.40e-2)" "unprognostic (3.67e-3)" "potential prognostic unfavorable (1.24e-4)" "unprognostic (2.16e-3)" "potential prognostic unfavorable (1.75e-6)" "unprognostic (6.65e-3)" "unprognostic (4.95e-2)" "unprognostic (7.26e-3)" "unprognostic (5.79e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (5.07e-5)" "unprognostic (2.72e-2)" "unprognostic (2.31e-2)" "unprognostic (2.95e-1)" "unprognostic (3.88e-2)" "unprognostic (8.44e-3)" "unprognostic (1.85e-1)" "unprognostic (4.70e-1)" "unprognostic (6.87e-2)" "unprognostic (1.82e-1)" S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3547.5;urinary bladder: 1021.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 10840.8;Epididymal basal cells: 3107.6;Esophageal apical cells: 19225.2;Esophageal basal cells: 20239.3;Esophageal suprabasal cells: 32841.1;Suprabasal keratinocytes: 5197.5" "Group enriched" "Detected in many" 12 "Apical squamous epithelial cells: 19225.2;Basal cells: 20239.3;Suprabasal cells: 32841.1" "Cell type enriched" "Detected in some" 4 "astrocyte: 5.6" "Group enriched" "Detected in all" 8 "Bladder Urothelial Carcinoma (TCGA): 2907.7;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 5064.2;Head and Neck Squamous Cell Carcinoma (TCGA): 6939.4;Lung Squamous Cell Carcinoma (TCGA): 2517.4" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 10.2" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.2" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 7682.4;head and neck cancer: 2632.4" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary gland basal cells, Skin - Hair cortex cells, Skin - Outer root sheath cells" "Not detected" "Not detected" "Region enriched" "Detected in single" 4 "spinal cord: 2.5" "Group enriched" "Detected in some" "Distal tubules: 1853455.0;Keratinocytes: 6192600.9;Large ducts: 3736687.2" "Tissue enhanced" "Detected in all" "skin: 15656005.5" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 89000 "Cluster 41: Basophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 39 "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: " "unprognostic (2.63e-3)" "unprognostic (5.15e-2)" "unprognostic (4.83e-2)" "unprognostic (7.96e-2)" "unprognostic (2.60e-2)" "unprognostic (2.48e-2)" "unprognostic (2.33e-1)" "unprognostic (3.64e-1)" "unprognostic (3.18e-1)" "unprognostic (7.96e-2)" "unprognostic (5.97e-2)" "potential prognostic unfavorable (6.73e-4)" "unprognostic (5.94e-2)" "unprognostic (1.04e-3)" "unprognostic (1.54e-2)" "unprognostic (3.79e-2)" "unprognostic (1.00e-3)" "unprognostic (2.82e-2)" "potential prognostic unfavorable (5.64e-4)" "unprognostic (2.46e-2)" "unprognostic (3.02e-1)" "potential prognostic unfavorable (3.73e-4)" "unprognostic (2.72e-3)" "unprognostic (3.49e-2)" "unprognostic (6.07e-2)" "unprognostic (7.01e-2)" "unprognostic (1.20e-1)" "unprognostic (2.27e-1)" "unprognostic (1.55e-1)" "unprognostic (1.98e-1)" "unprognostic (7.73e-2)" S100A3 S100E ENSG00000188015 "S100 calcium binding protein A3" P33764 1 153547329-153549258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 98.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "Bladder Urothelial Carcinoma (TCGA): 107.5;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 37.7;Uterine Corpus Endometrial Carcinoma (TCGA): 41.7" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "intermediate monocyte: 3.1;non-classical monocyte: 6.3;plasmacytoid DC: 7.5" "Group enriched" "Detected in many" 11 "dendritic cells: 7.5;monocytes: 6.3" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells, Skin - Inner root sheath cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.9" "Cell type enriched" "Detected in single" 4395 "Alveolar cell types: 439519.4" "Tissue enriched" "Detected in some" "lung: 2095938.2" "HPA042674, HPA056140" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA 52000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 9: Skin - Hair follicle development" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 108: Fibroblasts - ECM organization" 21 Cytosol "Golgi apparatus, Plasma membrane" "HPA042674: , HPA056140: " "unprognostic (2.33e-1)" "unprognostic (1.15e-1)" "unprognostic (1.33e-1)" "unprognostic (3.19e-2)" "unprognostic (2.72e-2)" "unprognostic (3.55e-2)" "unprognostic (9.71e-2)" "unprognostic (1.35e-1)" "unprognostic (1.37e-2)" "unprognostic (2.32e-1)" "unprognostic (2.62e-1)" "unprognostic (1.26e-2)" "unprognostic (1.45e-2)" "unprognostic (1.74e-1)" "unprognostic (1.40e-1)" "unprognostic (1.84e-2)" "unprognostic (1.12e-1)" "unprognostic (6.99e-2)" "unprognostic (1.58e-2)" "unprognostic (6.17e-2)" "unprognostic (3.47e-2)" "unprognostic (3.73e-3)" "unprognostic (2.36e-2)" "unprognostic (1.46e-3)" "unprognostic (1.57e-1)" "unprognostic (6.74e-2)" "unprognostic (2.38e-1)" "unprognostic (9.15e-2)" "unprognostic (5.00e-1)" "unprognostic (4.38e-2)" "unprognostic (7.75e-2)" S100A8 "60B8AG, CAGA, CFAG, CGLA, MRP-8, MRP8, P8, S100-A8" ENSG00000143546 "S100 calcium binding protein A8" P05109 1 153390032-153391073 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" Antimicrobial "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 33387.3;cervix: 14477.9;esophagus: 36526.2;vagina: 16753.2" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 442326.6;Esophageal suprabasal cells: 118514.7" "Group enriched" "Detected in many" 5 "Apical squamous epithelial cells: 442326.6;Suprabasal cells: 118514.7" "Cell type enriched" "Detected in single" 61 "leukocyte: 38.2" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 10785.2;Head and Neck Squamous Cell Carcinoma (TCGA): 12921.4" "Region enhanced" "Detected in all" "cerebral cortex: 66.1" "Group enriched" "Detected in all" 9 "classical monocyte: 26966.7;neutrophil: 53446.0" "Group enriched" "Detected in all" 9 "granulocytes: 53446.0;monocytes: 26966.7" "Group enriched" "Detected in many" 6 "breast cancer: 333.1;cervical cancer: 581.7;head and neck cancer: 730.8" "Adipose visceral - Neutrophils, Colon - Neutrophils, Heart muscle - Neutrophils, Liver - Neutrophils, Lung - Neutrophils_2, Pituitary gland - Neutrophils, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Neutrophils, Thyroid gland - Neutrophils" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in all" "Neutrophils: 1170046987.3" "Tissue enriched" "Detected in all" "bone marrow: 7207083898.5" "CAB002791, HPA024372" Enhanced Supported "Intermediate filaments,Cytosol" "Secreted to blood" Immunity NA NA 10900000 300000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 28 "Intermediate filaments" Cytosol "CAB002791: , HPA024372: " "unprognostic (2.27e-1)" "unprognostic (2.23e-1)" "unprognostic (1.06e-1)" "unprognostic (6.86e-2)" "unprognostic (3.03e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (9.35e-4)" "unprognostic (5.33e-2)" "unprognostic (1.02e-2)" "unprognostic (4.32e-1)" "unprognostic (1.03e-2)" "unprognostic (5.08e-2)" "unprognostic (5.07e-2)" "unprognostic (7.11e-2)" "unprognostic (9.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.75e-2)" "unprognostic (3.40e-1)" "unprognostic (1.31e-3)" "unprognostic (2.98e-1)" "unprognostic (3.31e-2)" "unprognostic (1.98e-2)" "unprognostic (5.58e-2)" "unprognostic (3.05e-2)" "unprognostic (8.69e-2)" "unprognostic (1.32e-1)" "unprognostic (2.19e-1)" "unprognostic (1.45e-1)" "unprognostic (1.99e-1)" "unprognostic (2.79e-2)" "unprognostic (1.86e-1)" S100B S100beta ENSG00000160307 "S100 calcium binding protein B" P04271 21 46598604-46605208 "Cancer-related genes, Candidate cardiovascular disease genes, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 4757.1" "Cell type enhanced" "Detected in many" "Astrocytes: 256.4;Bergmann glia: 670.9;Breast myoepithelial cells: 169.6;cDC: 159.1;Melanocytes: 211.1;Oligodendrocyte progenitor cells: 203.1;Oligodendrocytes: 513.3;Retinal pigment epithelial cells: 306.9;Schwann cells: 1448.6" "Cell type enriched" "Detected in many" 4 "Glial cells: 1448.6" "Cell type enhanced" "Detected in all" "Bergmann glia: 839.6;oligodendrocyte: 1025.9" "Group enriched" "Detected in many" 64 "Glioblastoma Multiforme (TCGA): 1024.8;Skin Cutaneous Melanoma (TCGA): 1223.7" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 361.7" "Lineage enriched" "Detected in all" 6 "T-cells: 361.7" "Cancer enriched" "Detected in many" 8 "skin cancer: 980.5" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Colon - Enteric glia cells, Minor Salivary Gland - Fibroblasts, Pituitary gland - Undifferentiated cells (Pituitary gland), Spleen - Macrophages, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 76120369.5;Microglia and Neuropil: 21521770.0" "Group enriched" "Detected in all" "cerebral cortex: 317642590.1;intestine: 196826529.3;skin: 98646060.3" "CAB000073, HPA015768, CAB078196" Enhanced Supported Approved "Nucleoplasm,Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body,Cytosol" "Secreted - unknown location" "Cell adhesion" Yes NA 140000 "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 69: Skin cancer - ECM organization" "Cluster 82: Dendritic cells - Antigen presentation" 56 "Vesicles, Primary cilium, Cytosol" "Nucleoplasm, Microtubules, Cytokinetic bridge, Mitotic spindle, Basal body" "CAB000073: , CAB078196: , HPA015768: " "unprognostic (3.93e-1)" "unprognostic (1.37e-3)" "unprognostic (5.60e-2)" "unprognostic (1.46e-2)" "unprognostic (6.70e-3)" "unprognostic (4.80e-2)" "unprognostic (1.22e-3)" "potential prognostic unfavorable (4.68e-6)" "unprognostic (1.28e-2)" "unprognostic (3.93e-2)" "unprognostic (4.77e-2)" "unprognostic (4.81e-3)" "unprognostic (6.77e-2)" "unprognostic (1.35e-1)" "unprognostic (6.50e-3)" "unprognostic (1.14e-1)" "unprognostic (7.40e-2)" "unprognostic (3.95e-2)" "unprognostic (3.53e-1)" "unprognostic (2.40e-1)" "unprognostic (2.82e-3)" "unprognostic (3.41e-2)" "unprognostic (1.33e-2)" "unprognostic (2.01e-1)" "unprognostic (4.23e-1)" "unprognostic (3.14e-1)" "unprognostic (2.74e-2)" "unprognostic (6.83e-2)" "unprognostic (1.10e-1)" "unprognostic (1.03e-1)" S100P ENSG00000163993 "S100 calcium binding protein P" P25815 4 6693878-6697170 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 1330.4;esophagus: 584.2;placenta: 445.8;stomach 1: 1640.9;urinary bladder: 1656.2" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 2056.3;Esophageal apical cells: 9537.5;Foveolar cells: 4417.9;Gastric progenitor cells: 1568.8;Neutrophils: 1944.7;Prostatic club cells: 3278.5;Prostatic hillock cells: 2245.5;Respiratory secretory cells: 1244.7;Syncytiotrophoblasts: 3446.9;Urothelial cells: 6283.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 9537.5;Barrier epithelial cells: 6283.0;Gastric glandular cells: 4417.9;Glandular cells: 3278.5;Trophoblast cells: 3446.9" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 2315.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 46 "basophil: 1796.7;eosinophil: 839.7;neutrophil: 2984.9" "Lineage enriched" "Detected in many" 73 "granulocytes: 2984.9" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Colon - Colon enterocytes, Heart muscle - Neutrophils, Liver - Neutrophils, Pituitary gland - Neutrophils, Prostate - Urothelial cells, Skeletal muscle - Neutrophils, Spleen - Neutrophils_2, Stomach - Gastric mucous cells, Testis - Late spermatids, Thyroid gland - Neutrophils" "Cell type enriched" "Detected in many" "Neutrophils: 82312258.2" "Tissue enriched" "Detected in all" "bone marrow: 489208547.8" "HPA019502, HPA075251" Enhanced Supported Nucleoplasm NA NA 3800000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 7: Liver cancer - Metabolism" "Cluster 84: Apical squamous epithelium - Cornification" 32 Nucleoplasm "HPA019502: , HPA075251: " "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (1.23e-1)" "unprognostic (3.65e-2)" "unprognostic (2.01e-1)" "unprognostic (2.43e-1)" "unprognostic (6.96e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (1.16e-3)" "unprognostic (3.78e-2)" "potential prognostic unfavorable (5.76e-4)" "unprognostic (1.55e-1)" "unprognostic (1.97e-1)" "unprognostic (7.75e-2)" "unprognostic (1.24e-1)" "unprognostic (1.54e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (1.78e-1)" "unprognostic (2.47e-2)" "unprognostic (8.13e-2)" "unprognostic (1.11e-1)" "unprognostic (5.01e-2)" "unprognostic (6.25e-2)" "unprognostic (1.77e-1)" "unprognostic (1.65e-1)" S100Z "Gm625, S100-zeta" ENSG00000171643 "S100 calcium binding protein Z" Q8WXG8 5 76850001-76921650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.2;lymphoid tissue: 2.9" "Cell type enhanced" "Detected in many" "cDC: 45.0;Hematopoietic stem cells: 71.8;Hofbauer cells: 32.8;Macrophages: 35.6;Microglia: 224.3;Monocyte progenitors: 62.4;monocytes: 81.6;Neutrophils: 68.0;Oocytes: 59.9;Thymocytes: 197.3" "Cell type enhanced" "Detected in many" "Glial cells: 224.3;Mononuclear phagocytes: 81.6;T-cells: 197.3" "Cell type enriched" "Detected in many" 4 "central nervous system macrophage: 257.6" "Cancer enhanced" "Detected in single" "Testicular Germ Cell Tumor (TCGA): 3.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 6 "classical monocyte: 35.1;eosinophil: 31.9;intermediate monocyte: 34.0;myeloid DC: 19.5;neutrophil: 11.9;non-classical monocyte: 39.7" "Group enriched" "Detected in many" 6 "dendritic cells: 19.5;granulocytes: 31.9;monocytes: 39.7" "Group enriched" "Detected in some" 6 "Leukemia: 5.4;lymphoma: 17.0" "Region enriched" "Detected in single" 5 "olfactory bulb: 1.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA051929 Approved Approved Nucleoplasm,Centrosome,Cytosol NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 11 "Centrosome, Cytosol" Nucleoplasm "HPA051929: " "unprognostic (2.32e-2)" "unprognostic (4.29e-2)" "unprognostic (2.42e-1)" S1PR1 "CD363, D1S3362, edg-1, EDG1" ENSG00000170989 "Sphingosine-1-phosphate receptor 1" P21453 1 101236865-101243713 "Cancer-related genes, CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "Angiogenesis, Chemotaxis" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 40.7;B-cells: 19.9;Bergmann glia: 71.3;Granulosa cells: 22.7;Hofbauer cells: 28.1;Innate lymphoid cells: 23.5;Lymphatic endothelial cells: 102.1;Müller glia: 36.6;NK-cells: 20.7;Thymocytes: 20.3;Vascular endothelial cells: 164.5" "Group enriched" "Detected in many" 4 "Endothelial cells: 164.5;Glial cells: 71.3" "Group enriched" "Detected in some" 6 "astrocyte: 43.8;Bergmann glia: 82.6;endothelial cell: 85.0;leukocyte: 21.3" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 58.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 1252.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 1843459.1;Microglia and Neuropil: 1053849.8" "Group enriched" "Detected in some" "cerebral cortex: 954881.3;lymphoid tissue: 248936.2" "CAB010104, HPA075568" Supported Supported Vesicles No NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 19: Astrocytes - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 56 Vesicles "CAB010104: , HPA075568: " "unprognostic (1.40e-1)" "unprognostic (2.82e-1)" "unprognostic (7.69e-2)" "unprognostic (1.55e-1)" "unprognostic (3.32e-2)" "unprognostic (2.60e-2)" "unprognostic (3.97e-1)" "unprognostic (4.16e-3)" "unprognostic (1.27e-3)" "unprognostic (1.87e-1)" "validated prognostic favorable (1.94e-9)" "validated prognostic favorable (6.68e-4)" "unprognostic (1.38e-2)" "unprognostic (4.46e-3)" "unprognostic (1.04e-2)" "unprognostic (2.21e-2)" "unprognostic (2.02e-1)" "unprognostic (3.68e-2)" "unprognostic (9.71e-2)" "unprognostic (2.80e-1)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (3.17e-1)" "unprognostic (1.67e-1)" "unprognostic (6.40e-2)" "unprognostic (3.43e-2)" "unprognostic (1.56e-2)" "unprognostic (4.92e-2)" "unprognostic (8.75e-2)" "unprognostic (1.53e-1)" "unprognostic (4.28e-1)" SAFB "HET, SAFB1" ENSG00000160633 "Scaffold attachment factor B" Q15424 19 5623035-5668478 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 39703781.1" "Low tissue specificity" "Detected in many" "CAB001969, HPA016832, HPA020076" Supported Enhanced Nucleoplasm,Midbody Yes NA 390000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 24: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 57 Nucleoplasm Midbody "CAB001969: , HPA016832: , HPA020076: " "unprognostic (1.84e-1)" "unprognostic (2.84e-1)" "unprognostic (1.48e-3)" "unprognostic (5.52e-2)" "unprognostic (1.50e-1)" "unprognostic (1.29e-1)" "unprognostic (6.16e-2)" "unprognostic (1.07e-2)" "unprognostic (1.34e-2)" "unprognostic (2.03e-1)" "unprognostic (1.19e-3)" "unprognostic (1.68e-3)" "unprognostic (7.48e-2)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (3.98e-2)" "unprognostic (1.24e-1)" "unprognostic (9.01e-3)" "unprognostic (1.43e-1)" "unprognostic (1.06e-3)" "unprognostic (1.58e-1)" "unprognostic (2.88e-2)" "unprognostic (1.34e-3)" "unprognostic (6.96e-3)" "unprognostic (7.03e-3)" "unprognostic (3.37e-2)" "unprognostic (4.74e-2)" "unprognostic (3.74e-2)" "unprognostic (6.85e-2)" "unprognostic (7.60e-2)" "unprognostic (3.72e-2)" "unprognostic (4.37e-2)" SAFB2 KIAA0138 ENSG00000130254 "Scaffold attachment factor B2" Q14151 19 5586999-5624046 "Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 55212088.6" "Low tissue specificity" "Detected in all" HPA050894 Approved Supported "Nucleoplasm,Nuclear bodies,Vesicles" NA NA 260000 "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Non-specific - Transcription" "Cluster 20: Non-specific - Transcription regulation" 49 Nucleoplasm "Nuclear bodies, Vesicles" "HPA050894: " "unprognostic (4.97e-2)" "unprognostic (6.83e-2)" "unprognostic (2.04e-2)" "unprognostic (1.27e-1)" "unprognostic (6.98e-3)" "unprognostic (2.83e-1)" "unprognostic (1.59e-1)" "unprognostic (2.64e-2)" "unprognostic (2.18e-3)" "unprognostic (6.18e-2)" "validated prognostic favorable (9.48e-5)" "validated prognostic favorable (7.59e-5)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (2.95e-1)" "unprognostic (1.00e-1)" "unprognostic (4.30e-1)" "unprognostic (4.61e-1)" "unprognostic (5.68e-2)" "unprognostic (2.16e-1)" "unprognostic (6.13e-2)" "potential prognostic favorable (1.90e-4)" "unprognostic (6.32e-3)" "potential prognostic unfavorable (7.31e-4)" "unprognostic (5.15e-2)" "unprognostic (4.56e-2)" "unprognostic (9.60e-2)" "unprognostic (2.00e-2)" "unprognostic (9.90e-2)" "unprognostic (2.73e-1)" "unprognostic (1.96e-2)" SAGE1 "CT14, SAGE" ENSG00000181433 "Sarcoma antigen 1" Q9NXZ1 X 135889205-135913062 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 14 "testis: 4.5" "Group enriched" "Detected in some" 11 "Differentiating spermatogonia: 16.5;Early primary spermatocytes: 4.2;Undifferentiated spermatogonia: 8.1" "Cell type enriched" "Detected in single" 18 "Spermatogenic cell types: 16.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 6.5" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003033, HPA003208" Enhanced Enhanced "Nucleoplasm,Nuclear bodies" NA NA "Cluster 67: Testis - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" Nucleoplasm "Nuclear bodies" "HPA003033: , HPA003208: " "unprognostic (5.46e-3)" "unprognostic (1.72e-1)" "unprognostic (4.08e-1)" SALL1 "Hsal1, TBS, ZNF794" ENSG00000103449 "Spalt like transcription factor 1" Q9NSC2 16 51135982-51152334 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2;kidney: 31.7;liver: 34.3" "Cell type enhanced" "Detected in some" "Astrocytes: 20.6;Cone photoreceptor cells: 37.3;Distal convoluted tubule cells: 24.1;Endometrial glandular cells: 19.3;Endometrial luminal cells: 21.4;Endometrial stromal cells: 25.6;Ependymal cells: 19.5;Epididymal efferent duct absorptive cells: 31.2;Hepatocytes: 44.7;Loop of henle epithelial cells: 54.4;Microglia: 84.9;Oligodendrocytes: 40.5;Pituitary stem cells: 73.9;Proximal tubule cells: 41.5" "Cell type enhanced" "Detected in many" "Glial cells: 84.9;Hepatocytes: 44.7;Neuronal cells: 37.3;Renal nephron cells: 54.4;Stem cells: 73.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 94.8;oligodendrocyte: 61.7" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 46.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Macrophages, Testis - Spermatogonia" "Region enhanced" "Detected in all" "olfactory bulb: 52.6" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5338 "Distal tubules: 533762.0" "Not detected" "Not detected" "HPA049829, HPA074673" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear speckles,Cytosol" NA NA "Cluster 76: Non-specific - Metabolism" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 18 Nucleoplasm "Nucleoli, Nuclear speckles, Cytosol" "HPA049829: , HPA074673: " "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "unprognostic (2.61e-1)" "unprognostic (1.01e-1)" "unprognostic (1.99e-1)" "unprognostic (9.13e-2)" "validated prognostic favorable (3.05e-10)" "validated prognostic favorable (8.08e-4)" "unprognostic (1.88e-2)" "unprognostic (2.94e-2)" "unprognostic (1.99e-3)" "unprognostic (1.98e-1)" "unprognostic (5.01e-2)" "unprognostic (8.29e-2)" "unprognostic (2.17e-3)" "unprognostic (2.98e-1)" "unprognostic (2.89e-2)" "unprognostic (5.54e-2)" SALL4 "dJ1112F19.1, ZNF797" ENSG00000101115 "Spalt like transcription factor 4" Q9UJQ4 20 51782331-51802521 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Deafness, Disease variant, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 3.8;thyroid gland: 5.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 21.3;Conjunctival goblet cells: 7.8;Gastric progenitor cells: 10.3;Oocytes: 9.2;Pancreatic duct cells: 11.1;Pancreatic islet cells: 7.7;Respiratory secretory cells: 7.2;Retinal horizontal cells: 30.1;Sertoli cells: 22.7;Undifferentiated spermatogonia: 11.1;Urothelial cells: 6.6" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 21.3;Neuronal cells: 30.1;Reproductive supporting cells: 22.7" "Cell type enhanced" "Detected in some" "fibroblast: 3.2" "Cancer enriched" "Detected in many" 14 "Testicular Germ Cell Tumor (TCGA): 52.8" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in single" 9 "NK-cell: 2.5" "Lineage enriched" "Detected in single" 9 "NK-cells: 2.5" "Cancer enhanced" "Detected in many" "testis cancer: 36.6" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 25862 "Oocytes: 2586181.6" "Not detected" "Not detected" "HPA015291, HPA015791" Enhanced Supported Nucleoplasm,Vesicles Yes No "Cluster 21: Testis - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 9 Nucleoplasm Vesicles "HPA015291: , HPA015791: " "unprognostic (2.29e-1)" "unprognostic (7.69e-2)" "unprognostic (2.71e-1)" "unprognostic (1.01e-1)" "unprognostic (1.87e-1)" "unprognostic (1.36e-1)" "unprognostic (3.52e-3)" "unprognostic (7.59e-2)" "unprognostic (2.05e-2)" "unprognostic (8.43e-2)" "unprognostic (7.08e-2)" "unprognostic (2.21e-2)" "unprognostic (8.18e-2)" "unprognostic (2.26e-1)" "unprognostic (1.37e-1)" "unprognostic (3.96e-1)" "unprognostic (2.63e-2)" "unprognostic (4.78e-3)" "unprognostic (3.95e-2)" "unprognostic (6.10e-2)" "unprognostic (2.99e-1)" "unprognostic (5.41e-2)" "unprognostic (2.87e-1)" "unprognostic (2.39e-3)" "unprognostic (7.89e-3)" SAMD4B "FLJ10211, hSmaug2, MGC99832, SMGB" ENSG00000179134 "Sterile alpha motif domain containing 4B" Q5PRF9 19 39342421-39385710 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 306.5;Neutrophils: 364.4" "Cell type enhanced" "Detected in all" "Neutrophils: 364.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 754615.5" "Group enriched" "Detected in many" "fallopian tube: 2059334.8;intestine: 1146631.7;lymphoid tissue: 1821496.5;salivary gland: 536510.4" "HPA016800, HPA059385" Approved Enhanced Cytosol No No "Cluster 35: Neutrophils - Protein binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 36 Cytosol "HPA016800: , HPA059385: " "unprognostic (7.22e-2)" "unprognostic (7.24e-2)" "unprognostic (1.92e-1)" "unprognostic (1.71e-3)" "unprognostic (8.92e-2)" "unprognostic (1.10e-2)" "unprognostic (2.35e-1)" "unprognostic (3.14e-1)" "unprognostic (2.27e-1)" "unprognostic (1.15e-1)" "unprognostic (1.18e-3)" "unprognostic (4.79e-2)" "unprognostic (1.71e-1)" "unprognostic (2.76e-2)" "unprognostic (4.84e-2)" "unprognostic (2.88e-2)" "unprognostic (1.23e-1)" "unprognostic (2.69e-2)" "unprognostic (1.37e-1)" "unprognostic (5.26e-2)" "unprognostic (2.85e-1)" "unprognostic (3.39e-2)" "unprognostic (7.87e-3)" "unprognostic (7.72e-2)" "unprognostic (9.12e-2)" "unprognostic (2.92e-3)" "unprognostic (2.38e-2)" "unprognostic (1.85e-1)" "unprognostic (4.66e-2)" "unprognostic (3.60e-2)" "unprognostic (1.42e-1)" SAMD5 dJ875H10.1 ENSG00000203727 "Sterile alpha motif domain containing 5" Q5TGI4 6 147508690-147737547 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 265.9;Distal convoluted tubule cells: 556.6;Lactotrophs: 462.1;Pancreatic islet cells: 311.1;Pituicytes/FSCs: 484.5;Proximal tubule cells: 432.3;Renal collecting duct intercalated cells: 373.3;Renal connecting tubule cells: 257.4;Retinal bipolar cells: 911.4;Sertoli cells: 643.8;Thyrotrophs: 329.4" "Cell type enhanced" "Detected in many" "Glial cells: 484.5;Neuronal cells: 911.4;Pituitary endocrine cells: 462.1;Renal nephron cells: 556.6;Reproductive supporting cells: 643.8" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 609.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary gland basal cells, Skeletal muscle - Fibroblasts, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Spleen - Fibroblasts_1, Stomach - Mitotic cells (Stomach), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA067811 Uncertain Supported Vesicles No No "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Vesicles "HPA067811: " "unprognostic (1.78e-2)" "unprognostic (6.11e-2)" "unprognostic (9.19e-2)" "unprognostic (6.98e-2)" "unprognostic (1.39e-1)" "unprognostic (2.64e-2)" "unprognostic (1.66e-1)" "unprognostic (7.10e-2)" "unprognostic (1.19e-1)" "validated prognostic favorable (1.59e-7)" "validated prognostic favorable (1.70e-6)" "potential prognostic unfavorable (1.37e-4)" "potential prognostic unfavorable (8.61e-5)" "potential prognostic favorable (5.83e-4)" "unprognostic (2.12e-1)" "unprognostic (6.88e-3)" "unprognostic (1.00e-1)" "unprognostic (9.79e-2)" "unprognostic (6.12e-3)" "unprognostic (2.76e-1)" "unprognostic (8.13e-2)" "unprognostic (7.06e-2)" "unprognostic (1.95e-3)" "unprognostic (1.13e-1)" "unprognostic (8.45e-2)" "unprognostic (2.37e-2)" "unprognostic (1.82e-2)" "unprognostic (1.73e-1)" SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951893 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "cDC: 445.9;Endometrial ciliated cells: 255.1;Fallopian tube ciliated cells: 331.7;Kupffer cells: 447.9;Macrophages: 329.5;Monocyte progenitors: 510.5;monocytes: 470.0;pDCs: 347.8;Schwann cells: 907.4" "Cell type enhanced" "Detected in all" "dendritic cells: 445.9;Glial cells: 907.4;Mononuclear phagocytes: 510.5" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 224.0;leukocyte: 211.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Minor Salivary Gland - Macrophages, Skin - Macrophages, Spleen - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cell types: 415485362.9;Macrophages: 537491412.7;T-cells: 412667765.9" "Tissue enhanced" "Detected in all" "lymphoid tissue: 251245175.0" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 28 Nucleoplasm "Plasma membrane" "HPA047072: " "unprognostic (1.23e-1)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (9.84e-2)" "unprognostic (1.47e-1)" "unprognostic (2.56e-1)" "unprognostic (1.55e-1)" "unprognostic (2.62e-1)" "unprognostic (3.64e-2)" "unprognostic (5.77e-2)" "potential prognostic favorable (3.04e-4)" "unprognostic (2.37e-1)" "unprognostic (1.27e-2)" "unprognostic (1.53e-2)" "unprognostic (2.86e-1)" "unprognostic (2.08e-1)" "unprognostic (3.04e-3)" "unprognostic (4.31e-2)" "unprognostic (2.85e-1)" "unprognostic (2.26e-2)" "unprognostic (1.73e-1)" "unprognostic (2.95e-1)" "unprognostic (2.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.58e-2)" "unprognostic (5.22e-2)" "unprognostic (2.02e-1)" "unprognostic (8.59e-2)" "unprognostic (2.99e-1)" "unprognostic (1.94e-1)" "unprognostic (1.09e-1)" SAMSN1 "HACS1, NASH1, SASH2, SH3D6B, SLy2" ENSG00000155307 "SAM domain, SH3 domain and nuclear localization signals 1" Q9NSI8 21 14485228-14658821 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 182.2;lymphoid tissue: 75.6" "Cell type enriched" "Detected in many" 5 "Neutrophils: 14700.2" "Cell type enriched" "Detected in many" 5 "Neutrophils: 14700.2" "Group enriched" "Detected in many" 115 "central nervous system macrophage: 770.3;leukocyte: 405.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 315.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Leukemia: 69.1;lymphoma: 33.7" "Adipose subcutaneous - Macrophages, Adrenal gland - Macrophages, Liver - Neutrophils" "Region enriched" "Detected in many" 6 "olfactory bulb: 20.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10005 "B-cells: 594565.7;Collecting ducts: 474472.2;Macrophages: 835778.1;Neutrophils: 1717619.3;T-cells: 1380133.9" "Group enriched" "Detected in some" "bone marrow: 369620.5;cerebral cortex: 865938.9;lymphoid tissue: 393909.8" "HPA010645, HPA017055, HPA046639" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 "Plasma membrane" Nucleoplasm "HPA010645: , HPA017055: , HPA046639: " "unprognostic (2.79e-2)" "unprognostic (7.69e-3)" "unprognostic (4.24e-1)" "unprognostic (3.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.51e-1)" "unprognostic (9.30e-2)" "unprognostic (7.43e-2)" "unprognostic (5.56e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-2)" "unprognostic (3.36e-1)" "unprognostic (8.57e-2)" "unprognostic (7.25e-2)" "unprognostic (2.89e-1)" "unprognostic (1.04e-2)" "unprognostic (2.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.75e-1)" "unprognostic (3.02e-1)" "unprognostic (1.62e-2)" "unprognostic (2.28e-3)" "unprognostic (1.95e-1)" "unprognostic (1.30e-1)" "unprognostic (1.20e-2)" "unprognostic (7.69e-2)" "unprognostic (7.58e-2)" "unprognostic (4.79e-2)" "unprognostic (1.72e-1)" "unprognostic (1.77e-1)" SAP30L "FLJ11526, NS4ATP2" ENSG00000164576 "SAP30 like" Q9HAJ7 5 154445997-154461053 "Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in single" 92751 "lymphoid tissue: 9275136.2" "HPA048665, HPA078308" Approved Supported "Nucleoplasm,Nucleoli fibrillar center" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 24: Neutrophils - Innate immunity signal integration" 24 "Nucleoplasm, Nucleoli fibrillar center" "HPA048665: , HPA078308: " "unprognostic (1.27e-3)" "unprognostic (7.09e-3)" "unprognostic (7.13e-3)" "unprognostic (3.68e-2)" "unprognostic (4.27e-2)" "unprognostic (2.98e-1)" "unprognostic (5.23e-2)" "unprognostic (3.15e-1)" "unprognostic (5.88e-3)" "unprognostic (5.85e-2)" "validated prognostic favorable (4.03e-9)" "validated prognostic favorable (4.85e-5)" "unprognostic (3.06e-1)" "unprognostic (7.74e-2)" "unprognostic (2.21e-2)" "unprognostic (1.66e-1)" "unprognostic (1.77e-1)" "unprognostic (1.61e-1)" "unprognostic (2.48e-1)" "unprognostic (1.62e-2)" "unprognostic (1.97e-1)" "unprognostic (9.03e-3)" "unprognostic (1.41e-1)" "unprognostic (3.48e-1)" "unprognostic (4.38e-2)" "unprognostic (1.56e-2)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (9.62e-2)" "unprognostic (1.25e-2)" "unprognostic (1.34e-1)" SART3 "KIAA0156, p110, RP11-13G14, TIP110" ENSG00000075856 "Spliceosome associated factor 3, U4/U6 recycling protein" Q15020 12 108522214-108561400 "Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "lymphoid tissue: 35453907.9" "HPA028840, HPA044322" Approved Supported Nucleoplasm No No 8100 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 49: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 119 Nucleoplasm "HPA028840: , HPA044322: " "unprognostic (1.90e-2)" "unprognostic (2.22e-2)" "unprognostic (2.16e-1)" "unprognostic (1.38e-1)" "unprognostic (2.15e-1)" "unprognostic (3.80e-3)" "unprognostic (3.30e-1)" "potential prognostic favorable (9.29e-5)" "unprognostic (1.41e-1)" "unprognostic (2.05e-2)" "unprognostic (6.04e-2)" "unprognostic (7.91e-3)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (2.69e-4)" "unprognostic (2.26e-2)" "unprognostic (1.16e-2)" "unprognostic (4.41e-2)" "unprognostic (1.43e-1)" "unprognostic (4.54e-3)" "unprognostic (8.61e-2)" "unprognostic (1.40e-2)" "unprognostic (2.40e-1)" "unprognostic (4.68e-3)" "unprognostic (5.25e-2)" "unprognostic (9.20e-2)" "unprognostic (4.73e-2)" "unprognostic (9.14e-2)" "unprognostic (1.23e-1)" "unprognostic (2.09e-1)" "unprognostic (4.86e-2)" "unprognostic (3.57e-1)" SATB2 "FLJ21474, KIAA1034" ENSG00000119042 "SATB homeobox 2" Q9UPW6 2 199269505-199471266 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, Developmental protein, DNA-binding, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 13.1;intestine: 30.8" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 139.5;Choroid plexus epithelial cells: 401.8;Colonocytes: 500.6;Enteric stem cells: 319.3;Enteric transient amplifying cells: 273.7;Ependymal cells: 185.6;Goblet cells: 280.1;Neuroendocrine cells: 239.7;Tuft cells: 403.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 401.8;Enterocytes: 500.6;Goblet cells: 280.1;Proliferating cells: 273.7;Secretory gland support: 403.5;Stem cells: 319.3" "Group enriched" "Detected in many" 4 "choroid plexus epithelial cell: 419.4;deep-layer corticothalamic and 6b: 493.3;deep-layer intratelencephalic: 540.6;deep-layer near-projecting: 363.5;ependymal cell: 195.2;hippocampal CA1-3: 296.1;miscellaneous: 439.0;upper-layer intratelencephalic: 516.6" "Cancer enhanced" "Detected in many" "Colon Adenocarcinoma (TCGA): 30.7;Rectum Adenocarcinoma (TCGA): 32.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Region enhanced" "Detected in many" "cerebral cortex: 29.2" "Group enriched" "Detected in all" 5 "cerebral cortex: 64.0;hippocampal formation: 51.0" "Group enriched" "Detected in some" 28614 "Microglia and Neuropil: 2375809.8;Neurons: 4878818.4;Oocytes: 1329483.6" "Tissue enriched" "Detected in single" 1248 "cerebral cortex: 124817.4" "HPA001042, CAB023669, HPA029543, CAB062562, CAB067751, CAB068229, CAB068230, CAB068231" Enhanced Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 17: Intestine - Digestion" "Cluster 53: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 24 Nucleoplasm "Centrosome, Basal body, Cytosol" "CAB023669: , CAB062562: , CAB067751: , CAB068229: , CAB068230: , CAB068231: , HPA001042: , HPA029543: " "unprognostic (8.56e-3)" "unprognostic (4.78e-2)" "unprognostic (2.08e-2)" "unprognostic (7.84e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-3)" "unprognostic (7.22e-2)" "unprognostic (1.49e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (8.56e-8)" "unprognostic (1.71e-3)" "potential prognostic favorable (7.31e-4)" "unprognostic (8.29e-2)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (7.87e-5)" "unprognostic (5.28e-2)" "unprognostic (1.93e-1)" "unprognostic (1.18e-1)" "unprognostic (6.37e-2)" "unprognostic (3.45e-2)" "unprognostic (1.67e-1)" "unprognostic (8.43e-2)" "unprognostic (1.56e-1)" "unprognostic (3.67e-2)" "unprognostic (8.59e-2)" "unprognostic (2.36e-1)" "unprognostic (2.12e-1)" SBSPON "C8orf84, RPESP" ENSG00000164764 "Somatomedin B and thrombospondin type 1 domain containing" Q8IVN8 8 73064543-73124088 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 21.4" "Cell type enhanced" "Detected in many" "Epididymal efferent duct absorptive cells: 71.5;Fallopian secretory cells: 45.3;Gastric chief cells: 63.3;Mucous neck cells: 81.8;Müller glia: 51.9;Podocytes: 314.6;Salivary myoepithelial cells: 45.5;Schwann cells: 114.4;Smooth muscle cells: 111.0;Vascular smooth muscle cells: 93.9" "Cell type enhanced" "Detected in many" "Glial cells: 114.4;Mural cells: 93.9;Renal nephron cells: 314.6;Smooth muscle cells: 111.0" "Group enriched" "Detected in many" 6 "astrocyte: 18.7;vascular associated smooth muscle cell: 47.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "white matter: 36.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 8.8" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 248 "fallopian tube: 12615.3;ovary: 37017.1" HPA029595 Approved Approved Vesicles "Secreted to extracellular matrix" "No annotated function" NA NA 7600 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 22: Non-specific - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 62: Smooth muscle cells - Muscle contraction" Vesicles "HPA029595: " "unprognostic (6.40e-3)" "potential prognostic favorable (7.47e-4)" "unprognostic (1.70e-2)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (3.74e-2)" "unprognostic (1.08e-1)" "unprognostic (9.45e-2)" "unprognostic (2.38e-2)" "unprognostic (6.74e-2)" "unprognostic (9.68e-2)" "unprognostic (1.06e-1)" "unprognostic (5.72e-2)" "unprognostic (3.52e-2)" "unprognostic (3.71e-1)" "unprognostic (2.36e-2)" "unprognostic (5.31e-2)" "unprognostic (1.69e-3)" "unprognostic (8.23e-2)" "unprognostic (1.27e-1)" "unprognostic (9.25e-2)" "unprognostic (1.50e-1)" "unprognostic (3.03e-1)" "unprognostic (1.10e-1)" "unprognostic (1.65e-1)" "unprognostic (5.44e-2)" SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 367.9" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 177.6;Esophageal apical cells: 167.5;Hepatocytes: 179.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland basal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9936 "Hepatocytes: 1341154.0;Neurons: 646102.6" "Tissue enriched" "Detected in single" 2991 "salivary gland: 299051.7" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 30: Non-specific - DNA binding" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 49: Hindbrain - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 2 "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: , HPA070248: " "unprognostic (9.31e-2)" "unprognostic (4.47e-2)" "unprognostic (5.06e-2)" "unprognostic (1.71e-1)" "unprognostic (2.34e-2)" "unprognostic (1.39e-1)" "unprognostic (1.34e-2)" "potential prognostic unfavorable (1.42e-4)" "unprognostic (4.01e-3)" "potential prognostic favorable (3.54e-9)" "unprognostic (5.97e-3)" "unprognostic (1.23e-1)" "unprognostic (1.93e-2)" "unprognostic (7.27e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-1)" "unprognostic (3.34e-1)" "unprognostic (1.77e-1)" "unprognostic (2.09e-2)" "unprognostic (4.07e-2)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (1.88e-1)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (4.13e-5)" "unprognostic (7.53e-2)" "unprognostic (2.70e-1)" "unprognostic (2.65e-1)" "unprognostic (2.79e-1)" SCAPER "Zfp291, ZNF291" ENSG00000140386 "S-phase cyclin A associated protein in the ER" Q9BY12 15 76347904-76905444 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 51.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 859.1;Rod photoreceptor cells: 2165.4" "Cell type enhanced" "Detected in all" "Neuronal cells: 2165.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1515204.6" "Group enriched" "Detected in some" 570 "cerebral cortex: 76351.8;lymphoid tissue: 37674.6" "HPA046253, HPA048077" Approved Supported "Nucleoplasm,Nuclear speckles,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA No "Cluster 22: Eosinophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 31: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 5 "Nucleoplasm, Nuclear speckles" "Primary cilium, Primary cilium tip, Basal body, Cytosol" "HPA046253: , HPA048077: " "unprognostic (6.75e-3)" "unprognostic (8.70e-2)" "unprognostic (1.70e-2)" "unprognostic (1.45e-1)" "unprognostic (2.94e-1)" "unprognostic (1.02e-1)" "unprognostic (3.68e-2)" "unprognostic (4.33e-2)" "unprognostic (3.42e-1)" "unprognostic (1.36e-2)" "validated prognostic favorable (1.08e-9)" "validated prognostic favorable (3.58e-4)" "unprognostic (8.54e-2)" "unprognostic (5.37e-2)" "unprognostic (2.26e-1)" "unprognostic (2.17e-2)" "unprognostic (2.15e-2)" "unprognostic (8.62e-2)" "unprognostic (2.44e-1)" "unprognostic (1.56e-1)" "unprognostic (5.27e-2)" "unprognostic (2.18e-1)" "unprognostic (3.81e-2)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (1.72e-1)" "unprognostic (2.37e-1)" "unprognostic (4.20e-1)" "unprognostic (3.13e-1)" "unprognostic (2.01e-1)" SCCPDH "CGI-49, NET11" ENSG00000143653 "Saccharopine dehydrogenase (putative)" Q8NBX0 1 246724409-246768137 "Metabolic proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 1240.6;Late primary spermatocytes: 2111.7" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 2111.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 20 "basophil: 875.3" "Lineage enriched" "Detected in all" 26 "granulocytes: 875.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Spleen - Macrophages, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "liver: 79872388.5" "HPA050775, HPA076030" Enhanced Approved Vesicles NA NA 29000 "Cluster 41: Basophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 45: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 5 Vesicles "HPA050775: , HPA076030: " "unprognostic (1.93e-1)" "unprognostic (2.42e-1)" "unprognostic (2.99e-1)" "unprognostic (1.48e-1)" "unprognostic (2.06e-2)" "unprognostic (3.73e-1)" "unprognostic (9.53e-2)" "unprognostic (9.58e-2)" "unprognostic (4.88e-2)" "unprognostic (8.87e-2)" "potential prognostic favorable (8.82e-4)" "unprognostic (1.39e-2)" "unprognostic (1.32e-1)" "unprognostic (3.56e-1)" "unprognostic (1.89e-1)" "unprognostic (5.80e-2)" "unprognostic (8.04e-2)" "unprognostic (1.68e-1)" "unprognostic (4.61e-2)" "unprognostic (1.27e-1)" "unprognostic (1.98e-1)" "unprognostic (2.26e-1)" "unprognostic (1.75e-1)" "unprognostic (7.42e-2)" "unprognostic (4.29e-2)" "unprognostic (3.78e-2)" "unprognostic (3.03e-1)" "unprognostic (1.75e-2)" "unprognostic (6.90e-2)" "unprognostic (5.31e-2)" "unprognostic (3.13e-1)" SCD "FADS5, SCD1, SCDOS" ENSG00000099194 "Stearoyl-CoA desaturase" O00767 10 100347233-100364826 "Enzymes, Essential proteins, Metabolic proteins, Predicted membrane proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 1158.4;brain: 979.4;liver: 546.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 631.7;Esophageal apical cells: 705.3;Esophageal suprabasal cells: 429.7;Hepatocytes: 250.3;Kupffer cells: 211.1;Oligodendrocytes: 541.0;Respiratory ionocytes: 188.0;Transitional alveolar cells: 201.4" "Cell type enhanced" "Detected in many" "Alveolar cells: 631.7;Apical squamous epithelial cells: 705.3;Glial cells: 541.0;Suprabasal cells: 429.7" "Group enriched" "Detected in all" 5 "committed oligodendrocyte precursor: 205.0;oligodendrocyte: 714.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Spleen - Macrophages, Testis - Sertoli cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 7832658.9" "Group enriched" "Detected in some" "cerebral cortex: 263314.0;lung: 68846.2" "HPA012107, HPA063921" Approved Enhanced "Endoplasmic reticulum" No Yes 27000 "Cluster 30: Non-specific - DNA binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 53 "Endoplasmic reticulum" "HPA012107: , HPA063921: " "potential prognostic unfavorable (9.23e-4)" "unprognostic (1.14e-1)" "unprognostic (2.12e-1)" "unprognostic (2.38e-3)" "unprognostic (3.43e-2)" "unprognostic (4.36e-2)" "unprognostic (1.65e-1)" "unprognostic (4.61e-1)" "unprognostic (4.15e-2)" "unprognostic (1.80e-3)" "unprognostic (2.07e-1)" "unprognostic (5.24e-2)" "unprognostic (3.02e-2)" "unprognostic (5.93e-2)" "unprognostic (1.25e-2)" "unprognostic (6.16e-3)" "unprognostic (1.14e-1)" "unprognostic (3.25e-1)" "unprognostic (1.03e-1)" "unprognostic (2.93e-1)" "unprognostic (4.87e-1)" "unprognostic (8.85e-2)" "unprognostic (9.55e-2)" "unprognostic (8.12e-2)" "unprognostic (8.88e-2)" "unprognostic (3.19e-2)" "unprognostic (4.18e-2)" "unprognostic (6.96e-2)" "unprognostic (2.25e-1)" "unprognostic (8.36e-2)" "unprognostic (8.74e-3)" SCEL "FLJ21667, MGC22531" ENSG00000136155 Sciellin O95171 13 77535674-77645263 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 350.3;skin 1: 285.8" "Cell type enriched" "Detected in many" 8 "Esophageal apical cells: 7219.7" "Cell type enriched" "Detected in many" 8 "Apical squamous epithelial cells: 7219.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 3.3;cerebellar inhibitory: 4.4;oligodendrocyte: 4.9" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 34.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 54.0;pancreatic cancer: 51.0" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 1" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Keratinocytes: 161087245.3" "Tissue enhanced" "Detected in many" "lung: 36669499.5;Stomach: 30888246.6" "HPA039737, HPA040154" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 6000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 6 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA039737: , HPA040154: " "unprognostic (1.53e-1)" "unprognostic (9.94e-2)" "unprognostic (3.01e-2)" "unprognostic (2.33e-2)" "unprognostic (1.12e-1)" "potential prognostic favorable (6.10e-4)" "unprognostic (8.53e-2)" "unprognostic (5.68e-2)" "unprognostic (3.85e-2)" "unprognostic (1.12e-1)" "unprognostic (4.71e-2)" "unprognostic (2.20e-1)" "validated prognostic unfavorable (1.22e-4)" "validated prognostic unfavorable (5.97e-4)" "unprognostic (9.40e-2)" "unprognostic (1.07e-1)" "unprognostic (1.59e-1)" "unprognostic (3.42e-1)" "unprognostic (1.00e-2)" "unprognostic (1.38e-2)" SCG2 "CHGC, SgII, SN" ENSG00000171951 "Secretogranin II" P13521 2 223596940-223602361 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "adrenal gland: 340.0;brain: 391.8;pituitary gland: 267.0" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 691.4;Brain inhibitory neurons: 181.4;Corticotrophs: 1184.6;Gonadotrophs: 341.0;Neuroendocrine cells: 280.8;Other brain neurons: 346.4;Pancreatic islet cells: 2077.8;Retinal amacrine cells: 166.7" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 691.4;Pancreatic islet cells: 2077.8;Pituitary endocrine cells: 1184.6" "Cell type enhanced" "Detected in all" "CGE interneuron: 475.9" "Group enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 110.0;Pancreatic Adenocarcinoma (TCGA): 84.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 319.4;Rhabdoid: 457.9" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 48022145.9;Microglia and Neuropil: 26088584.4;Neurons: 16428190.5;Pancreatic islets: 34591373.2" "Tissue enriched" "Detected in many" "cerebral cortex: 259041207.2" "HPA011893, HPA075062" Enhanced Supported Approved "Golgi apparatus,Vesicles" "Secreted to blood" "No annotated function" NA NA 300000 "Cluster 36: Brain & Liver - Signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 3 "Golgi apparatus" Vesicles "HPA011893: , HPA075062: " "unprognostic (4.35e-1)" "unprognostic (1.96e-2)" "unprognostic (1.57e-1)" "unprognostic (1.32e-2)" "unprognostic (2.64e-2)" "unprognostic (1.09e-2)" "unprognostic (6.77e-2)" "unprognostic (1.70e-2)" "unprognostic (2.18e-1)" "unprognostic (1.57e-3)" "unprognostic (3.15e-2)" "unprognostic (5.40e-3)" "unprognostic (1.93e-3)" "unprognostic (2.16e-1)" "unprognostic (1.87e-1)" "unprognostic (6.80e-2)" "unprognostic (1.73e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (3.26e-4)" "unprognostic (2.07e-2)" "unprognostic (6.90e-2)" "unprognostic (6.12e-3)" "unprognostic (1.02e-1)" "unprognostic (9.68e-2)" "unprognostic (6.19e-3)" "unprognostic (2.93e-1)" "unprognostic (6.30e-3)" SCGN "CALBL, DJ501N12.8, SECRET, SEGN" ENSG00000079689 "Secretagogin, EF-hand calcium binding protein" O76038 6 25652201-25701783 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.4;pancreas: 44.4;pituitary gland: 35.4" "Group enriched" "Detected in some" 5 "Brain inhibitory neurons: 17.4;Other brain neurons: 49.5" "Cell type enriched" "Detected in some" 8 "Neuronal cells: 49.5" "Cell type enriched" "Detected in some" 4 "cerebellar inhibitory: 199.3" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 50.6;Pancreatic Adenocarcinoma (TCGA): 56.6" "Group enriched" "Detected in many" 6 "cerebellum: 35.9;hippocampal formation: 28.2;hypothalamus: 92.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Gastric cancer: 8.1;lung cancer: 19.8;Neuroblastoma: 6.9;prostate cancer: 9.7;thyroid cancer: 7.0" "Colon - Colon enteroendocrine cells, Pituitary gland - Somatotropes, Stomach - Gastric enteroendocrine cells, Testis - Spermatogonia" "Region enriched" "Detected in many" 16 "olfactory bulb: 82.0" "Region enriched" "Detected in many" 10 "olfactory bulb: 183.0" "Cell type enriched" "Detected in many" "Pancreatic islets: 509154178.2" "Tissue enhanced" "Detected in many" "intestine: 19712935.4" "CAB004005, HPA006641, CAB044060, CAB062563, CAB068232" Enhanced Supported Supported Cytosol "Intracellular and membrane" "No annotated function" NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 16: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 48 Cytosol "CAB004005: , CAB044060: , CAB062563: , CAB068232: , HPA006641: " "unprognostic (6.96e-2)" "unprognostic (3.28e-1)" "unprognostic (2.43e-1)" "unprognostic (5.09e-2)" "unprognostic (6.24e-2)" "validated prognostic favorable (1.29e-6)" "validated prognostic favorable (1.04e-5)" "unprognostic (1.55e-1)" "unprognostic (5.24e-3)" "unprognostic (5.19e-3)" "unprognostic (2.98e-1)" "unprognostic (4.84e-1)" "unprognostic (4.40e-1)" "unprognostic (1.42e-2)" "unprognostic (1.11e-1)" "unprognostic (4.58e-1)" "unprognostic (1.24e-1)" "unprognostic (3.00e-2)" "unprognostic (4.30e-2)" SCIN KIAA1905 ENSG00000006747 Scinderin Q9Y6U3 7 12570577-12660182 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.6;kidney: 44.0;placenta: 73.1" "Cell type enhanced" "Detected in many" "Enterocytes: 553.9;Hofbauer cells: 240.6;Loop of henle epithelial cells: 170.6;Microglia: 170.7;Ocular epithelial cells: 210.7;Renal collecting duct intercalated cells: 731.0;Renal collecting duct principal cells: 321.9;Renal connecting tubule cells: 330.9;Respiratory ionocytes: 172.7" "Cell type enhanced" "Detected in many" "Ductal cells: 731.0;Enterocytes: 553.9" "Group enriched" "Detected in many" 7 "central nervous system macrophage: 213.2;ependymal cell: 163.0" "Group enriched" "Detected in many" 4 "Kidney Chromophobe (TCGA): 190.5;Kidney Renal Papillary Cell Carcinoma (TCGA): 95.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Lung - Alveolar cells type 2, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Collecting ducts: 349778073.3" "Group enriched" "Detected in many" "intestine: 71193882.4;kidney: 62256072.5" "HPA020518, HPA024264" Enhanced Approved "Plasma membrane,Cytosol" No No 5500000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 6 "Plasma membrane" Cytosol "HPA020518: , HPA024264: " "unprognostic (1.85e-2)" "unprognostic (2.40e-2)" "unprognostic (1.77e-1)" "unprognostic (3.29e-1)" "unprognostic (1.36e-1)" "unprognostic (3.09e-2)" "unprognostic (5.45e-2)" "unprognostic (1.38e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-2)" "unprognostic (6.47e-2)" "unprognostic (5.36e-3)" "unprognostic (1.16e-2)" "unprognostic (2.83e-1)" "unprognostic (1.91e-1)" "unprognostic (1.87e-1)" "unprognostic (4.26e-2)" "unprognostic (4.68e-2)" "unprognostic (3.41e-1)" "unprognostic (1.38e-1)" "unprognostic (6.88e-2)" "unprognostic (8.90e-2)" "unprognostic (1.17e-1)" "unprognostic (4.07e-2)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (2.40e-1)" "unprognostic (1.60e-1)" "unprognostic (5.04e-2)" "unprognostic (3.42e-2)" "unprognostic (1.95e-1)" SCLY SCL ENSG00000132330 "Selenocysteine lyase" Q96I15 2 238060924-238099413 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lyase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 37.5" "Group enriched" "Detected in some" 6 "Astrocytes: 31.6;Bergmann glia: 25.8;Brain excitatory neurons: 35.3;Brain inhibitory neurons: 32.6;Choroid plexus epithelial cells: 40.3;Early spermatids: 45.0;Ependymal cells: 29.1;Late spermatids: 86.6;Microglia: 36.0;Oligodendrocyte progenitor cells: 36.2;Oligodendrocytes: 54.0;Other brain neurons: 22.0" "Group enriched" "Detected in many" 14 "Ciliated cells: 40.3;Glial cells: 54.0;Neuronal cells: 35.3;Spermatogenic cell types: 86.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 41712126.5;Pancreas epithelial cells: 39741299.0;Pancreatic islets: 35865283.9" "Group enriched" "Detected in all" "kidney: 111165697.1;liver: 108464320.3;pancreas: 101443344.6" "HPA020190, HPA055760" Uncertain Enhanced "Golgi apparatus" NA NA 200000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 8 "Golgi apparatus" "HPA020190: , HPA055760: " "unprognostic (1.19e-1)" "unprognostic (2.58e-2)" "unprognostic (4.71e-2)" "unprognostic (9.10e-2)" "unprognostic (1.73e-1)" "unprognostic (3.56e-1)" "unprognostic (2.31e-1)" "unprognostic (9.03e-2)" "unprognostic (1.04e-2)" "unprognostic (3.05e-1)" "potential prognostic favorable (1.92e-6)" "unprognostic (1.54e-3)" "unprognostic (5.43e-2)" "unprognostic (4.94e-2)" "unprognostic (8.53e-2)" "unprognostic (2.39e-2)" "unprognostic (1.66e-1)" "unprognostic (5.27e-2)" "unprognostic (1.50e-2)" "unprognostic (7.97e-2)" "unprognostic (2.19e-1)" "unprognostic (2.80e-2)" "unprognostic (3.34e-1)" "unprognostic (2.17e-1)" "unprognostic (1.74e-1)" "unprognostic (3.59e-1)" "unprognostic (6.25e-2)" "unprognostic (2.10e-2)" "unprognostic (4.58e-2)" "unprognostic (1.03e-2)" "unprognostic (1.48e-1)" SCMH1 Scml3 ENSG00000010803 "Scm polycomb group protein homolog 1" Q96GD3 1 41027202-41242306 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Developmental protein, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 84 "Granulosa cells: 4938.7;Neurons: 11949.0" "Not detected" "Not detected" "HPA048898, HPA053292" Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 35: Non-specific - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 15 Nucleoplasm "Nuclear bodies, Cytosol" "HPA048898: , HPA053292: " "unprognostic (2.16e-3)" "unprognostic (1.89e-1)" "unprognostic (3.38e-1)" "unprognostic (6.37e-2)" "unprognostic (2.33e-2)" "unprognostic (3.62e-1)" "unprognostic (3.97e-2)" "unprognostic (7.77e-2)" "unprognostic (4.01e-1)" "unprognostic (1.06e-2)" "unprognostic (7.65e-3)" "unprognostic (1.67e-2)" "potential prognostic favorable (1.81e-5)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (3.39e-3)" "unprognostic (1.26e-2)" "unprognostic (9.42e-2)" "unprognostic (2.63e-2)" "unprognostic (1.68e-1)" "unprognostic (4.94e-2)" "unprognostic (3.87e-2)" "unprognostic (1.17e-1)" "unprognostic (2.99e-1)" "unprognostic (1.34e-1)" "unprognostic (7.06e-2)" "unprognostic (1.88e-1)" "unprognostic (2.17e-1)" "unprognostic (5.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.41e-1)" "unprognostic (6.35e-2)" SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 7.9;retina: 3.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 178.2;Brain excitatory neurons: 336.0;Brain inhibitory neurons: 430.0;Ependymal cells: 573.7;Fallopian tube ciliated cells: 190.3;Oligodendrocyte progenitor cells: 835.0;Other brain neurons: 230.2;Pituicytes/FSCs: 233.7;Retinal bipolar cells: 155.3;Retinal ganglion cells: 421.0" "Cell type enhanced" "Detected in many" "Alveolar cells: 178.2;Ciliated cells: 573.7;Glial cells: 835.0;Neuronal cells: 430.0" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 7 "Glioblastoma Multiforme (TCGA): 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Lung - Alveolar cells type 2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2810 "Astrocytes and Neuropil: 309338.6;Microglia and Neuropil: 323262.4;Neurons: 210537.9" "Tissue enriched" "Detected in single" 25569 "cerebral cortex: 2556923.5" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 1 "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: " "unprognostic (4.38e-1)" "unprognostic (7.03e-3)" SCN3B "HSA243396, SCNB3" ENSG00000166257 "Sodium voltage-gated channel beta subunit 3" Q9NY72 11 123629187-123655244 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.3;pituitary gland: 26.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Brain excitatory neurons: 100.9;Brain inhibitory neurons: 80.6;Corticotrophs: 40.7;Lactotrophs: 178.4;Late spermatids: 50.9;Lymphatic endothelial cells: 175.2;Other brain neurons: 96.6;Retinal amacrine cells: 146.3;Somatotrophs: 72.1;Thyrotrophs: 139.4" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 74.5;Endothelial cells: 175.2;Neuronal cells: 146.3;Pituitary endocrine cells: 178.4" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 12 "Neuroblastoma: 18.0" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Pituitary gland - Lactotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13801 "Astrocytes and Neuropil: 1495342.2;Microglia and Neuropil: 1608349.5;Neurons: 1036474.3" "Tissue enriched" "Detected in single" 124631 "cerebral cortex: 12463097.4" HPA078632 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 128 "Plasma membrane, Cytosol" Vesicles "HPA078632: " "unprognostic (7.64e-3)" "unprognostic (3.89e-2)" "unprognostic (1.77e-3)" "unprognostic (3.80e-1)" "unprognostic (4.31e-2)" "unprognostic (1.94e-3)" "unprognostic (2.30e-1)" "unprognostic (4.97e-2)" SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 16.9;pituitary gland: 6.3;retina: 7.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 152.4;Brain excitatory neurons: 367.3;Brain inhibitory neurons: 321.4;Corticotrophs: 194.7;Gonadotrophs: 255.9;Lactotrophs: 245.8;Oligodendrocyte progenitor cells: 137.2;Other brain neurons: 185.7;Retinal amacrine cells: 157.0;Retinal bipolar cells: 120.7;Retinal ganglion cells: 166.1;Retinal horizontal cells: 140.2;Somatotrophs: 250.8;Thyrotrophs: 256.4" "Cell type enhanced" "Detected in many" "Glial cells: 152.4;Neuronal cells: 367.3;Pituitary endocrine cells: 256.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13061 "Astrocytes and Neuropil: 1327643.2;Microglia and Neuropil: 1365154.1;Neurons: 1225363.0" "Tissue enriched" "Detected in single" 46272 "cerebral cortex: 4627242.1" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 1 "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (1.37e-1)" "unprognostic (2.40e-1)" "unprognostic (7.00e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (7.21e-2)" "unprognostic (8.57e-3)" "unprognostic (3.78e-1)" "potential prognostic favorable (3.92e-4)" "unprognostic (1.68e-2)" "unprognostic (2.49e-1)" "unprognostic (2.75e-1)" "unprognostic (2.10e-1)" "unprognostic (2.70e-1)" SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.7" "Cell type enhanced" "Detected in many" "Corticotrophs: 202.7;Ependymal cells: 167.2;Hofbauer cells: 347.3;Macrophages: 142.0;Oligodendrocyte progenitor cells: 299.5;Other brain neurons: 285.9;pDCs: 172.6;Respiratory ionocytes: 243.8;Retinal ganglion cells: 146.8;Schwann cells: 176.1;Sertoli cells: 810.0;Somatotrophs: 155.0" "Cell type enhanced" "Detected in many" "Glial cells: 299.5;Mononuclear phagocytes: 347.3;Neuronal cells: 285.9;Reproductive supporting cells: 810.0" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 408.5" "Cancer enhanced" "Detected in some" "Lung Squamous Cell Carcinoma (TCGA): 4.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cancer enhanced" "Detected in many" "Rhabdoid: 44.7" "Adrenal gland - Adrenal medulla cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 266 "Collecting ducts: 19935.0;Neurons: 33180.1" "Not detected" "Not detected" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 5: Rhabdoid - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: " "unprognostic (3.00e-1)" "unprognostic (1.04e-1)" "unprognostic (5.89e-2)" "unprognostic (1.14e-2)" "unprognostic (2.70e-2)" "unprognostic (7.62e-2)" "unprognostic (2.59e-2)" "unprognostic (4.04e-1)" "unprognostic (3.27e-2)" "unprognostic (1.61e-2)" "unprognostic (2.96e-2)" "unprognostic (1.02e-1)" "unprognostic (7.58e-3)" "unprognostic (1.78e-1)" SCNN1A "ENaCalpha, SCNN1" ENSG00000111319 "Sodium channel epithelial 1 subunit alpha" P37088 12 6346843-6377730 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 184.9;salivary gland: 149.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 393.4;Alveolar cells type 2: 299.0;Conjunctival goblet cells: 371.8;Endometrial luminal cells: 370.9;Esophageal apical cells: 424.6;Goblet cells: 372.4;Renal collecting duct intercalated cells: 288.1;Respiratory secretory cells: 296.1;Salivary duct cells: 508.6;Salivary ionocytes: 441.9;Transitional alveolar cells: 295.7" "Cell type enhanced" "Detected in many" "Alveolar cells: 393.4;Apical squamous epithelial cells: 424.6;Ductal cells: 508.6;Ionocytes: 441.9" "Cell type enriched" "Detected in some" 51 "choroid plexus epithelial cell: 140.0" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 391.1" "Region enriched" "Detected in some" 18 "choroid plexus: 243.0" "Immune cell enhanced" "Detected in some" "neutrophil: 1.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" "Large ducts: 3209975.3" "Tissue enriched" "Detected in single" 23 "salivary gland: 2309.5" HPA012743 Enhanced Uncertain Vesicles,Acrosome,Annulus NA NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 36: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 10 "Vesicles, Annulus" Acrosome "HPA012743: " "unprognostic (2.62e-1)" "unprognostic (2.33e-1)" "unprognostic (7.00e-2)" "unprognostic (2.80e-1)" "unprognostic (4.49e-2)" "unprognostic (3.20e-1)" "unprognostic (1.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.92e-2)" "unprognostic (1.19e-2)" "unprognostic (3.10e-3)" "unprognostic (2.15e-1)" "unprognostic (3.39e-2)" "unprognostic (1.40e-1)" "unprognostic (1.08e-1)" "unprognostic (3.93e-3)" "unprognostic (1.62e-1)" "validated prognostic unfavorable (2.14e-4)" "validated prognostic unfavorable (6.66e-4)" "unprognostic (1.51e-1)" "unprognostic (1.33e-1)" "unprognostic (7.18e-3)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (2.11e-1)" "unprognostic (6.85e-2)" "unprognostic (1.42e-1)" SCP2 ENSG00000116171 "Sterol carrier protein 2" P22307 1 52927276-53051698 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1042.5" "Cell type enhanced" "Detected in all" "Breast lactating cells: 764.6;Enterocytes: 748.6;Esophageal apical cells: 1043.5;Hepatocytes: 1656.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1043.5;Hepatocytes: 1656.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Hepatocytes: 277824839.3;Proximal tubules: 72862004.1" "Tissue enriched" "Detected in all" "liver: 519773365.1" "HPA027101, HPA027135, HPA027317" Supported Supported Nucleoplasm,Peroxisomes NA NA 280000 "Cluster 25: Non-specific - Unknown function" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 37: Non-specific - mRNA processing" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 6 Peroxisomes Nucleoplasm "HPA027101: , HPA027135: , HPA027317: " "potential prognostic favorable (1.14e-5)" "unprognostic (5.35e-2)" "unprognostic (2.89e-1)" "unprognostic (1.92e-1)" "potential prognostic favorable (3.31e-4)" "unprognostic (9.33e-2)" "unprognostic (5.39e-2)" "unprognostic (3.43e-1)" "unprognostic (8.15e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (2.14e-10)" "unprognostic (6.43e-2)" "unprognostic (2.61e-2)" "unprognostic (6.46e-3)" "unprognostic (3.72e-3)" "unprognostic (1.37e-1)" "unprognostic (3.38e-2)" "unprognostic (2.10e-1)" "unprognostic (1.24e-1)" "unprognostic (1.71e-1)" "unprognostic (4.60e-2)" "unprognostic (9.65e-3)" "unprognostic (1.28e-2)" "unprognostic (2.40e-1)" "unprognostic (3.27e-1)" "unprognostic (4.51e-2)" "unprognostic (9.18e-3)" "unprognostic (2.04e-2)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (1.49e-1)" SCRN1 KIAA0193 ENSG00000136193 "Secernin 1" Q12765 7 29920104-29990289 "Enzymes, Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 157.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 76497140.6;Microglia and Neuropil: 53329094.4;Neurons: 41961184.2" "Tissue enriched" "Detected in all" "cerebral cortex: 408046879.4" HPA024517 Enhanced Approved Cytosol No No 330000 "Cluster 29: Non-specific - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 7 Cytosol "HPA024517: " "unprognostic (4.83e-1)" "unprognostic (1.06e-3)" "unprognostic (1.55e-1)" "unprognostic (1.33e-2)" "unprognostic (1.91e-1)" "unprognostic (2.63e-1)" "unprognostic (1.03e-1)" "potential prognostic unfavorable (6.17e-5)" "unprognostic (4.01e-1)" "unprognostic (5.07e-3)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (5.26e-2)" "potential prognostic unfavorable (3.65e-4)" "unprognostic (1.77e-1)" "unprognostic (7.46e-2)" "unprognostic (3.09e-2)" "unprognostic (1.18e-1)" "unprognostic (5.97e-1)" "potential prognostic unfavorable (4.37e-4)" "unprognostic (2.13e-2)" "unprognostic (1.25e-2)" "unprognostic (1.60e-1)" "unprognostic (3.37e-1)" "unprognostic (3.75e-1)" "unprognostic (4.36e-3)" "unprognostic (9.56e-2)" "unprognostic (4.26e-2)" "unprognostic (3.08e-1)" "unprognostic (4.12e-1)" "unprognostic (1.42e-2)" SDAD1 FLJ10498 ENSG00000198301 "SDA1 domain containing 1" Q9NVU7 4 75940950-75990962 "Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Ribosome biogenesis, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 15466857.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9558.9;Stomach: 8468.8" HPA035949 Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 40 "Nucleoplasm, Nucleoli" "HPA035949: " "unprognostic (1.99e-1)" "unprognostic (5.21e-3)" "unprognostic (2.64e-1)" "unprognostic (5.34e-2)" "unprognostic (2.16e-2)" "unprognostic (5.27e-3)" "unprognostic (1.43e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (1.10e-4)" "potential prognostic favorable (3.87e-4)" "unprognostic (7.69e-2)" "unprognostic (8.91e-2)" "potential prognostic unfavorable (2.50e-5)" "unprognostic (4.12e-2)" "unprognostic (6.24e-2)" "unprognostic (2.96e-3)" "unprognostic (1.30e-1)" "unprognostic (9.47e-3)" "unprognostic (1.69e-2)" "unprognostic (2.39e-1)" "unprognostic (2.78e-2)" "unprognostic (8.20e-2)" "unprognostic (4.74e-2)" "unprognostic (6.25e-2)" "unprognostic (3.07e-1)" "unprognostic (3.50e-1)" "unprognostic (1.25e-1)" "unprognostic (3.25e-1)" "unprognostic (1.70e-2)" "unprognostic (8.57e-2)" SDC3 "N-syndecan, SYND3" ENSG00000162512 "Syndecan 3" O75056 1 30869466-30908758 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 129.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 102.3;Decidual stromal cells: 95.0;Kupffer cells: 597.5;Late spermatids: 153.5;Oligodendrocyte progenitor cells: 195.0" "Cell type enhanced" "Detected in many" "Glial cells: 195.0;Mononuclear phagocytes: 597.5;Spermatogenic cell types: 153.5" "Cell type enhanced" "Detected in all" "oligodendrocyte precursor cell: 176.6" "Group enriched" "Detected in all" 5 "Glioblastoma Multiforme (TCGA): 240.4;Skin Cutaneous Melanoma (TCGA): 236.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in all" "skin cancer: 203.7" "Colon - Smooth muscle cells, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Microglia and Neuropil: 306267.3" "Tissue enriched" "Detected in single" 11053 "cerebral cortex: 1105327.5" "HPA017087, CAB025786, HPA048085" Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 73: Brain - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Mitochondria Nucleoplasm "CAB025786: , HPA017087: , HPA048085: " "unprognostic (2.01e-2)" "unprognostic (5.73e-3)" "unprognostic (1.86e-2)" "unprognostic (8.99e-2)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (1.10e-1)" "unprognostic (1.77e-2)" "unprognostic (1.95e-1)" "unprognostic (3.41e-2)" "unprognostic (1.96e-2)" "unprognostic (3.24e-1)" "unprognostic (3.65e-2)" "unprognostic (1.45e-2)" "unprognostic (1.57e-1)" "unprognostic (4.89e-2)" "unprognostic (4.01e-2)" "unprognostic (1.15e-1)" "unprognostic (5.64e-1)" "unprognostic (5.06e-3)" "unprognostic (4.73e-2)" "unprognostic (1.76e-1)" "unprognostic (3.41e-2)" "unprognostic (1.50e-2)" "unprognostic (5.04e-2)" "unprognostic (8.75e-3)" "unprognostic (1.86e-2)" "unprognostic (8.98e-3)" "unprognostic (1.69e-1)" "unprognostic (3.54e-2)" "unprognostic (1.26e-1)" SDCBP2 "SITAC18, ST-2" ENSG00000125775 "Syndecan binding protein 2" Q9H190 20 1309909-1329139 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 140.3;intestine: 128.8;stomach 1: 96.0" "Cell type enhanced" "Detected in many" "Colonocytes: 835.1;Enterocytes: 536.3;Esophageal apical cells: 1781.9;Esophageal suprabasal cells: 365.7;Foveolar cells: 340.7;Pancreatic acinar cells: 210.0;Urothelial cells: 214.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 1781.9;Enterocytes: 835.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Gastric cancer: 28.9" "Colon - Colon enterocytes, Prostate - Urothelial cells, Skin - Keratinocyte (granular), Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Keratinocytes: 2695925.4" "Tissue enhanced" "Detected in many" "fallopian tube: 1322508.2" "HPA005804, HPA064490" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 17: Intestine - Digestion" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 51 Nucleoplasm "Golgi apparatus, Cytosol" "HPA005804: , HPA064490: " "unprognostic (7.32e-2)" "unprognostic (1.13e-2)" "unprognostic (5.08e-2)" "unprognostic (2.42e-1)" "unprognostic (2.07e-1)" "unprognostic (4.03e-2)" "unprognostic (1.14e-1)" "unprognostic (3.11e-1)" "unprognostic (4.21e-2)" "unprognostic (2.88e-2)" "validated prognostic favorable (9.36e-5)" "validated prognostic favorable (1.98e-4)" "unprognostic (3.26e-1)" "unprognostic (3.78e-2)" "unprognostic (2.28e-1)" "unprognostic (1.23e-3)" "unprognostic (3.85e-1)" "unprognostic (4.85e-2)" "unprognostic (8.61e-2)" "unprognostic (2.83e-2)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (5.00e-4)" "unprognostic (7.31e-2)" "unprognostic (1.32e-1)" "unprognostic (6.35e-2)" "unprognostic (6.72e-3)" "unprognostic (7.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.01e-1)" "unprognostic (1.74e-2)" "unprognostic (2.79e-2)" SDCCAG8 "BBS16, CCCAP, NPHP10, NY-CO-8, SLSN7" ENSG00000054282 "SHH signaling and ciliogenesis regulator SDCCAG8" Q86SQ7 1 243256034-243500091 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Leber congenital amaurosis, Nephronophthisis, Obesity, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 262.4;Bergmann glia: 244.4;Brain excitatory neurons: 190.5;Brain inhibitory neurons: 189.7;Choroid plexus epithelial cells: 363.4;Distal convoluted tubule cells: 260.4;Ependymal cells: 299.5;Loop of henle epithelial cells: 204.3;Microglia: 729.4;Oligodendrocyte progenitor cells: 252.7;Oligodendrocytes: 399.9;Podocytes: 192.0;Proximal tubule cells: 189.3;Renal collecting duct intercalated cells: 219.5;Renal collecting duct principal cells: 232.7;Renal connecting tubule cells: 231.1" "Cell type enhanced" "Detected in all" "Ciliated cells: 363.4;Ductal cells: 232.7;Glial cells: 729.4;Renal nephron cells: 260.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 1199617.9" "Tissue enriched" "Detected in single" 1061 "fallopian tube: 106076.2" "HPA025737, HPA044477, HPA072495" Approved Supported "Primary cilium,Centrosome,Basal body" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 6 "Centrosome, Basal body" "Primary cilium" "HPA025737: , HPA044477: , HPA072495: " "unprognostic (3.50e-3)" "unprognostic (2.48e-1)" "unprognostic (8.36e-2)" "unprognostic (4.50e-2)" "unprognostic (7.77e-2)" "unprognostic (6.15e-2)" "unprognostic (2.42e-1)" "unprognostic (4.68e-2)" "unprognostic (1.69e-2)" "unprognostic (2.75e-2)" "unprognostic (2.23e-2)" "unprognostic (1.49e-1)" "unprognostic (1.17e-1)" "unprognostic (1.11e-1)" "unprognostic (4.73e-1)" "unprognostic (3.61e-1)" "unprognostic (6.86e-2)" "unprognostic (2.75e-2)" "unprognostic (3.02e-2)" "unprognostic (1.24e-1)" "unprognostic (1.11e-1)" "unprognostic (8.03e-2)" "unprognostic (9.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.37e-1)" "unprognostic (7.65e-2)" "unprognostic (1.68e-1)" "unprognostic (3.13e-1)" "unprognostic (1.83e-1)" "unprognostic (6.97e-3)" "unprognostic (4.87e-2)" SDHA "FP, SDH2, SDHF" ENSG00000073578 "Succinate dehydrogenase complex flavoprotein subunit A" P31040 5 218303-257082 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Cardiomyopathy, Disease variant, FDA approved drug targets, Leigh syndrome, Neurodegeneration, Primary mitochondrial disease, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 522.4;skeletal muscle: 446.5" "Cell type enhanced" "Detected in many" "Astrocytes: 32.2;Bergmann glia: 35.4;Brain excitatory neurons: 46.0;Brain inhibitory neurons: 39.5;Choroid plexus epithelial cells: 61.8;Distal convoluted tubule cells: 76.1;Ependymal cells: 35.9;Loop of henle epithelial cells: 63.2;Oligodendrocyte progenitor cells: 37.7;Oligodendrocytes: 52.3;Other brain neurons: 36.1;Papillary tip epithelial cells: 34.5;Podocytes: 41.8;Proximal tubule cells: 55.6;Renal collecting duct intercalated cells: 91.3;Renal collecting duct principal cells: 54.1;Renal connecting tubule cells: 75.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 61.8;Ductal cells: 91.3;Glial cells: 52.3;Neuronal cells: 46.0;Renal nephron cells: 76.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 801226130.5" "Tissue enhanced" "Detected in all" "heart muscle: 475167046.5" "CAB034929, HPA041981" Enhanced Supported "Plasma membrane,Mitochondria" No No 230000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 45: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 102: Non-specific - Mixed function" 52 Mitochondria "Plasma membrane" "CAB034929: , HPA041981: " "unprognostic (1.54e-2)" "potential prognostic unfavorable (8.39e-4)" "unprognostic (1.05e-1)" "unprognostic (1.24e-3)" "unprognostic (2.59e-2)" "unprognostic (2.63e-1)" "unprognostic (1.10e-1)" "unprognostic (3.26e-2)" "unprognostic (4.44e-1)" "unprognostic (1.11e-2)" "potential prognostic favorable (5.99e-4)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.56e-4)" "unprognostic (3.64e-2)" "unprognostic (1.24e-1)" "unprognostic (2.35e-2)" "unprognostic (2.44e-2)" "unprognostic (1.76e-1)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (3.13e-2)" "unprognostic (1.64e-1)" "unprognostic (1.68e-1)" "unprognostic (8.02e-2)" "unprognostic (3.00e-1)" "unprognostic (1.87e-2)" "unprognostic (1.93e-1)" "unprognostic (8.31e-2)" "unprognostic (2.58e-1)" "unprognostic (2.89e-1)" "unprognostic (1.91e-1)" SDHAF1 LYRM8 ENSG00000205138 "Succinate dehydrogenase complex assembly factor 1" A6NFY7 19 35995188-35996312 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Chaperone "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Cardiomyocytes: 1212799.3" "Group enriched" "Detected in some" "cerebral cortex: 370284.2;heart muscle: 328359.5;liver: 313946.8" "HPA064277, HPA074563" Supported Mitochondria NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 4 Mitochondria "HPA064277: , HPA074563: " "unprognostic (2.85e-3)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (8.89e-5)" "unprognostic (1.86e-1)" "unprognostic (4.81e-2)" "unprognostic (7.68e-2)" "unprognostic (1.80e-1)" "unprognostic (1.74e-1)" "unprognostic (6.76e-2)" "unprognostic (5.41e-2)" "unprognostic (2.30e-3)" "unprognostic (1.39e-1)" "potential prognostic favorable (2.61e-4)" "unprognostic (2.05e-2)" "unprognostic (3.63e-2)" "unprognostic (6.65e-2)" "unprognostic (1.70e-1)" "unprognostic (3.48e-3)" "unprognostic (4.94e-2)" "unprognostic (3.81e-2)" "unprognostic (1.51e-1)" "unprognostic (1.77e-3)" "unprognostic (2.72e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-2)" "unprognostic (7.97e-3)" "unprognostic (2.32e-2)" "unprognostic (1.09e-1)" "unprognostic (4.15e-1)" "unprognostic (1.43e-1)" "unprognostic (1.22e-1)" SDHAF4 "C6orf57, Sdh8" ENSG00000154079 "Succinate dehydrogenase complex assembly factor 4" Q5VUM1 6 70566917-70589569 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "cerebral cortex: 22319846.9;heart muscle: 47703625.6;kidney: 27650259.3;liver: 13003677.8" HPA031824 Supported Approved Nucleoplasm,Mitochondria No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 89: Adipocytes - Lipid metabolism" 4 Mitochondria Nucleoplasm "HPA031824: " "unprognostic (5.34e-2)" "unprognostic (3.36e-3)" "unprognostic (1.04e-1)" "unprognostic (9.94e-2)" "unprognostic (2.31e-2)" "unprognostic (2.94e-1)" "unprognostic (1.33e-1)" "unprognostic (2.60e-1)" "unprognostic (7.63e-3)" "potential prognostic favorable (5.17e-4)" "unprognostic (2.38e-3)" "potential prognostic favorable (1.59e-4)" "unprognostic (8.56e-2)" "unprognostic (1.20e-1)" "unprognostic (1.12e-2)" "unprognostic (3.15e-2)" "unprognostic (2.23e-1)" "unprognostic (2.04e-3)" "unprognostic (2.21e-1)" "unprognostic (4.94e-2)" "unprognostic (5.25e-2)" "unprognostic (1.21e-1)" "unprognostic (1.31e-2)" "unprognostic (4.47e-3)" "unprognostic (7.71e-2)" "unprognostic (5.88e-2)" "unprognostic (8.58e-2)" "unprognostic (1.68e-1)" "unprognostic (3.24e-1)" SDSL "cSDH, SDS-RS1" ENSG00000139410 "Serine dehydratase like" Q96GA7 12 113422380-113438276 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" "Isomerase, Lyase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 102.4" "Cell type enhanced" "Detected in many" "Colonocytes: 51.0;Enterocytes: 57.7;Epididymal efferent duct absorptive cells: 43.5;Epididymal principal cells: 49.8;Hepatocytes: 122.2;Hofbauer cells: 60.6" "Cell type enhanced" "Detected in many" "Hepatocytes: 122.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 8.7;intermediate monocyte: 10.0;myeloid DC: 18.5;plasmacytoid DC: 17.9" "Group enriched" "Detected in many" 6 "dendritic cells: 18.5;monocytes: 10.0" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 77.6" "Adrenal gland - Adrenal cortex cells, Lung - Macrophages, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal tubules: 38119575.2" "Tissue enhanced" "Detected in many" "liver: 6836877.7" HPA005740 Approved Approved Cytosol NA NA 25000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 27: Breast cancer - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 Cytosol "HPA005740: " "unprognostic (6.19e-2)" "unprognostic (2.12e-1)" "unprognostic (2.92e-1)" "unprognostic (1.11e-1)" "unprognostic (2.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.49e-2)" "unprognostic (2.44e-1)" "unprognostic (5.25e-2)" "potential prognostic unfavorable (8.13e-7)" "unprognostic (1.15e-2)" "unprognostic (1.26e-1)" "unprognostic (2.99e-3)" "unprognostic (8.71e-2)" "unprognostic (4.59e-2)" "unprognostic (7.38e-3)" "unprognostic (1.73e-2)" "unprognostic (5.42e-2)" "unprognostic (6.38e-3)" "unprognostic (6.85e-3)" "unprognostic (9.59e-2)" "unprognostic (1.32e-2)" "unprognostic (9.98e-2)" "unprognostic (2.65e-1)" "unprognostic (5.06e-2)" "unprognostic (7.75e-2)" "unprognostic (3.24e-2)" "unprognostic (1.33e-2)" "unprognostic (1.30e-2)" "unprognostic (1.01e-1)" "unprognostic (1.33e-3)" SEC11A "SEC11L1, sid2895, SPC18, SPCS4A" ENSG00000140612 "SEC11 homolog A, signal peptidase complex subunit" P67812 15 84669538-84716460 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 864.8" "Cell type enhanced" "Detected in all" "Trophoblast cells: 864.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 63917453.0" "Low tissue specificity" "Detected in many" HPA047533 Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 75: Ovary - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 58: Non-specific - Nuclear processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 34 "Nuclear membrane" "Golgi apparatus" "HPA047533: " "unprognostic (2.82e-1)" "unprognostic (1.83e-1)" "unprognostic (9.62e-2)" "unprognostic (1.36e-2)" "unprognostic (5.35e-2)" "unprognostic (3.64e-2)" "unprognostic (3.09e-1)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (2.14e-5)" "unprognostic (1.25e-1)" "potential prognostic favorable (4.01e-7)" "unprognostic (1.77e-2)" "unprognostic (1.86e-1)" "unprognostic (3.51e-2)" "potential prognostic unfavorable (4.68e-7)" "unprognostic (5.63e-2)" "unprognostic (3.56e-2)" "unprognostic (8.45e-2)" "unprognostic (1.69e-1)" "unprognostic (3.25e-2)" "unprognostic (1.15e-1)" "unprognostic (3.61e-3)" "unprognostic (1.39e-2)" "unprognostic (1.98e-2)" "unprognostic (2.61e-1)" "unprognostic (1.94e-2)" "unprognostic (5.22e-2)" "unprognostic (6.17e-2)" "unprognostic (2.57e-1)" "unprognostic (1.55e-1)" "unprognostic (8.51e-3)" SEC11C "SEC11L3, SPC21, SPCS4C" ENSG00000166562 "SEC11 homolog C, signal peptidase complex subunit" Q9BY50 18 59139866-59158832 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 989.1;Pancreatic islet cells: 472.0;Plasma cells: 1835.8;Prostatic glandular cells: 792.4;Respiratory ionocytes: 807.7;Salivary acinar cells: 569.0" "Cell type enhanced" "Detected in all" "Ionocytes: 807.7;Plasma cells: 1835.8;Reproductive supporting cells: 989.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 521.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 868.3" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Pancreas epithelial cells: 127291931.5;Pancreatic islets: 56743838.0" "Group enriched" "Detected in many" "pancreas: 52554305.5;salivary gland: 19849644.9" "HPA026816, HPA047533" Approved Approved "Nuclear membrane,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 44: Plasma cells - Antibody production & secretion" 25 "Nuclear membrane" "Golgi apparatus" "HPA026816: , HPA047533: " "unprognostic (1.17e-1)" "unprognostic (1.92e-1)" "unprognostic (2.82e-1)" "unprognostic (3.55e-1)" "unprognostic (6.12e-2)" "unprognostic (2.04e-1)" "unprognostic (2.01e-3)" "unprognostic (3.32e-1)" "unprognostic (3.26e-3)" "unprognostic (4.28e-2)" "potential prognostic favorable (3.34e-6)" "unprognostic (9.65e-2)" "unprognostic (1.29e-1)" "unprognostic (9.14e-2)" "unprognostic (3.90e-2)" "potential prognostic favorable (8.92e-4)" "unprognostic (9.61e-3)" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (3.46e-2)" "unprognostic (8.36e-3)" "unprognostic (5.72e-3)" "unprognostic (1.53e-1)" "unprognostic (1.11e-1)" "unprognostic (1.34e-1)" "unprognostic (9.87e-3)" "unprognostic (1.99e-1)" "unprognostic (1.40e-1)" "unprognostic (7.65e-2)" "unprognostic (1.47e-1)" "unprognostic (4.38e-2)" SELENOH "C11orf31, SELH" ENSG00000211450 "Selenoprotein H" Q8IZQ5 11 57741491-57743554 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 111.4;Enteric stem cells: 114.3;Enteric transient amplifying cells: 125.3;Enterocytes: 111.1;Epididymal efferent duct absorptive cells: 131.4;Epididymal efferent duct ciliated cells: 124.7;Epididymal principal cells: 189.9;Gastric chief cells: 131.0;Goblet cells: 111.5;Neuroendocrine cells: 102.2;Paneth cells: 96.7;Parietal cells: 102.5" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 189.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 18917584.7;T-cells: 18490102.2" "Tissue enhanced" "Detected in many" "lymphoid tissue: 15324737.1" HPA048362 Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 3 "Nucleoplasm, Nucleoli" "HPA048362: " "unprognostic (2.35e-1)" "unprognostic (3.01e-2)" "unprognostic (1.46e-1)" "unprognostic (2.51e-1)" "unprognostic (5.21e-2)" "unprognostic (1.25e-1)" "unprognostic (8.46e-2)" "unprognostic (4.07e-2)" "unprognostic (5.34e-3)" "unprognostic (3.86e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "potential prognostic unfavorable (5.44e-6)" "unprognostic (1.13e-1)" "unprognostic (1.81e-2)" "unprognostic (1.21e-1)" "unprognostic (3.24e-1)" "potential prognostic favorable (2.79e-5)" "unprognostic (4.19e-2)" "unprognostic (1.43e-1)" "unprognostic (4.02e-1)" "unprognostic (1.64e-2)" "unprognostic (7.02e-2)" "unprognostic (6.99e-3)" "potential prognostic unfavorable (9.98e-4)" "unprognostic (1.63e-1)" "unprognostic (3.47e-2)" "unprognostic (3.51e-1)" "unprognostic (7.37e-2)" SELENOO SELO ENSG00000073169 "Selenoprotein O" Q9BVL4 22 50201011-50217616 "Enzymes, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 26.5" "Cell type enhanced" "Detected in all" "Hepatocytes: 151.9;Late spermatids: 267.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 267.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 18351704.4;Proximal tubules: 26750961.9" "Tissue enhanced" "Detected in many" "heart muscle: 16764097.5" "HPA071795, HPA079100" Approved Supported "Mitotic chromosome,Mitochondria" Yes NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 70: Non-specific - Protein processing" "Cluster 2: Neurons - Nucleosome" "Cluster 66: Non-specific - Mitochondria" "Cluster 88: Proximal tubular cells - Transmembrane transport" 8 Mitochondria "Mitotic chromosome" "HPA071795: , HPA079100: " "unprognostic (1.38e-1)" "unprognostic (5.07e-2)" "unprognostic (5.00e-2)" "unprognostic (2.17e-1)" "unprognostic (7.41e-3)" "unprognostic (2.77e-1)" "unprognostic (5.35e-3)" "unprognostic (6.66e-2)" "unprognostic (2.35e-2)" "unprognostic (2.14e-3)" "unprognostic (1.34e-3)" "unprognostic (1.70e-2)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (3.38e-1)" "unprognostic (3.63e-1)" "unprognostic (3.21e-2)" "unprognostic (2.07e-2)" "unprognostic (1.33e-2)" "unprognostic (3.71e-2)" "unprognostic (4.58e-2)" "unprognostic (7.22e-2)" "unprognostic (3.52e-3)" "unprognostic (3.79e-2)" "unprognostic (2.40e-1)" "unprognostic (1.18e-1)" "unprognostic (4.48e-1)" "unprognostic (9.64e-2)" "unprognostic (2.74e-1)" SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 119.6" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 277.5;Ocular epithelial cells: 245.4;Prostatic hillock cells: 284.8;Urothelial cells: 418.6" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 418.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 17.0;naive B-cell: 15.0;neutrophil: 5.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Prostate - Urothelial cells, Spleen - Fibroblasts_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 1498745.2" "Group enriched" "Detected in many" "intestine: 2720119.8;lymphoid tissue: 3731400.2" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 67000000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 69: Urothelial cells - Basic cellular functions" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: " "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (2.66e-2)" "unprognostic (1.83e-3)" "unprognostic (1.98e-2)" "unprognostic (1.59e-2)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (2.05e-2)" "unprognostic (1.16e-1)" "unprognostic (3.40e-3)" "unprognostic (1.49e-2)" "unprognostic (4.22e-3)" "unprognostic (1.09e-3)" "potential prognostic unfavorable (5.35e-4)" "validated prognostic unfavorable (2.10e-4)" "validated prognostic unfavorable (1.30e-7)" "unprognostic (5.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (3.23e-2)" "unprognostic (1.66e-3)" "unprognostic (4.19e-3)" "unprognostic (6.40e-2)" "unprognostic (6.72e-2)" "unprognostic (1.99e-2)" "unprognostic (1.76e-1)" "unprognostic (1.21e-1)" "unprognostic (2.79e-1)" "unprognostic (1.80e-2)" "unprognostic (5.19e-2)" SEMA4D "C9orf164, CD100, coll-4, FLJ39737, SEMAJ" ENSG00000187764 "Semaphorin 4D" Q92854 9 89360787-89498130 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 325.7" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 269.9;Microglia: 235.2;Neutrophils: 756.5;Oligodendrocytes: 483.4;Platelets: 219.5;T-cells: 239.3" "Cell type enhanced" "Detected in all" "Glial cells: 483.4;Neutrophils: 756.5" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 286.4;committed oligodendrocyte precursor: 512.8;leukocyte: 361.0;oligodendrocyte: 549.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Leukemia: 47.6" "Colon - T-cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 1318804.8;Microglia and Neuropil: 2106965.6" "Tissue enhanced" "Detected in some" "bone marrow: 8951388.3;cerebral cortex: 12222580.3" "HPA015662, HPA023277" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium transition zone,Centrosome,Basal body" NA NA 2800000 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 59: Leukemia - T-cell receptor" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 "Plasma membrane" "Nucleoplasm, Vesicles, Primary cilium transition zone, Centrosome, Basal body" "HPA015662: , HPA023277: " "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (5.62e-2)" "unprognostic (2.60e-1)" "unprognostic (7.72e-2)" "unprognostic (1.91e-1)" "unprognostic (2.01e-1)" "unprognostic (1.12e-1)" "unprognostic (1.88e-2)" "unprognostic (2.51e-2)" "potential prognostic favorable (7.28e-5)" "unprognostic (1.15e-2)" "unprognostic (6.21e-2)" "unprognostic (1.20e-1)" "unprognostic (3.53e-2)" "unprognostic (2.02e-1)" "unprognostic (3.13e-2)" "unprognostic (2.13e-2)" "unprognostic (1.35e-2)" "unprognostic (2.82e-1)" "unprognostic (5.16e-2)" "unprognostic (4.96e-2)" "unprognostic (2.94e-2)" "unprognostic (6.56e-2)" "unprognostic (6.53e-2)" "unprognostic (4.42e-3)" "unprognostic (2.93e-2)" "unprognostic (6.61e-2)" "unprognostic (1.05e-1)" "unprognostic (4.68e-1)" "unprognostic (4.19e-2)" SEMA5B "FLJ10372, KIAA1445, SEMAG, SemG" ENSG00000082684 "Semaphorin 5B" Q9P283 3 122909082-123028605 "Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 34.8;Brain inhibitory neurons: 32.1;Cardiomyocytes: 28.4;Ependymal cells: 37.4;Müller glia: 53.8;Oligodendrocyte progenitor cells: 79.2;Oligodendrocytes: 67.5;Pericytes: 36.0;Retinal bipolar cells: 28.7;Vascular smooth muscle cells: 19.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 37.4;Glial cells: 79.2;Mural cells: 36.0;Myocytes: 28.4;Neuronal cells: 34.8" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 302.0;eccentric medium spiny neuron: 277.9" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 90.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 13.1;Kidney cancer: 23.3" "Liver - Hepatic stellate cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA066548 Enhanced Supported Cytosol NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Cytosol "HPA066548: " "unprognostic (2.88e-1)" "unprognostic (1.11e-2)" "unprognostic (7.60e-2)" "unprognostic (2.30e-2)" "unprognostic (6.53e-2)" "unprognostic (8.50e-2)" "unprognostic (1.45e-2)" "unprognostic (2.03e-1)" "unprognostic (2.42e-1)" "potential prognostic favorable (1.80e-5)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (3.95e-2)" "unprognostic (1.29e-1)" "unprognostic (1.07e-3)" "unprognostic (1.34e-2)" "unprognostic (2.36e-1)" "unprognostic (1.02e-1)" "unprognostic (6.24e-2)" "unprognostic (8.18e-2)" "unprognostic (5.69e-2)" "unprognostic (2.54e-2)" "unprognostic (1.19e-3)" "unprognostic (1.30e-1)" "unprognostic (3.62e-2)" "unprognostic (1.35e-2)" SEMA6A "HT018, KIAA1368, SEMA, SEMA6A1, SEMAQ" ENSG00000092421 "Semaphorin 6A" Q9H2E6 5 116443555-116574823 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 60.3;brain: 54.1" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 800.9;Bergmann glia: 250.5;Cardiomyocytes: 525.3;Colonocytes: 257.7;Cytotrophoblasts: 328.2;Epicardial cells: 336.6;Lymphatic endothelial cells: 408.6;Oligodendrocytes: 387.0;Retinal horizontal cells: 280.5;Syncytiotrophoblasts: 835.3" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 800.9;Myocytes: 525.3;Trophoblast cells: 835.3" "Cell type enhanced" "Detected in all" "endothelial cell: 403.6;oligodendrocyte: 521.9" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 81.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "testis cancer: 203.7" "Liver - Sinusoid Endothelial cells, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1441 "Astrocytes and Neuropil: 144104.1" "Tissue enriched" "Detected in single" 24 "cerebral cortex: 2421.6" "HPA031264, HPA031265, HPA031267" Approved Approved "Nucleoplasm,Nuclear bodies,Intermediate filaments" NA NA 670000 "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Nucleoplasm "Nuclear bodies, Intermediate filaments" "HPA031264: , HPA031265: , HPA031267: " "unprognostic (2.18e-1)" "unprognostic (6.53e-2)" "unprognostic (7.82e-3)" "unprognostic (6.55e-2)" "unprognostic (4.26e-3)" "unprognostic (4.30e-2)" "unprognostic (2.18e-2)" "unprognostic (9.72e-2)" "unprognostic (2.81e-1)" "unprognostic (7.81e-2)" "validated prognostic favorable (1.03e-4)" "validated prognostic favorable (2.00e-4)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.94e-4)" "unprognostic (4.00e-2)" "unprognostic (3.40e-1)" "unprognostic (2.37e-1)" "unprognostic (5.45e-2)" "unprognostic (1.10e-2)" "unprognostic (8.69e-2)" "unprognostic (4.49e-2)" "unprognostic (1.07e-2)" "unprognostic (9.18e-2)" "unprognostic (6.66e-2)" "unprognostic (6.27e-2)" "unprognostic (2.92e-1)" "unprognostic (2.06e-1)" "unprognostic (3.65e-3)" "unprognostic (2.27e-1)" "unprognostic (5.36e-3)" "unprognostic (1.33e-2)" SEMA7A "CD108, H-Sema-L, SEMAL" ENSG00000138623 "Semaphorin 7A (John Milton Hagen blood group)" O75326 15 74409289-74433958 "Blood group antigen proteins, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Inflammatory response, Neurogenesis" "Developmental protein" "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.8;lymphoid tissue: 55.3;retina: 32.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 11.7;Brain inhibitory neurons: 3.4;Megakaryocytes: 6.2;Microglia: 10.6;Oligodendrocyte progenitor cells: 4.7;Oligodendrocytes: 18.1;Papillary tip epithelial cells: 4.6;Podocytes: 3.4;Tuft cells: 11.5" "Group enriched" "Detected in some" 4 "Glial cells: 18.1;Megakaryocytes: 6.2;Neuronal cells: 11.7;Renal nephron cells: 4.6;Secretory gland support: 11.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 1.8;eosinophil: 3.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.1" "Low cancer specificity" "Detected in all" "Pituitary gland - Gonadotropes, Skin - Keratinocyte (granular), Stomach - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 1072520.8;Granulosa cells: 3385593.5;Microglia and Neuropil: 1240875.8;Neurons: 1206634.4" "Tissue enhanced" "Detected in many" "cerebral cortex: 4325756.9;intestine: 5925625.4" "HPA008210, HPA042273" Uncertain Uncertain Vesicles NA NA 9500000 "Cluster 22: Eosinophils - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 55: Lymphoma - Immune response" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 3 Vesicles "HPA008210: , HPA042273: " "unprognostic (2.98e-1)" "unprognostic (2.95e-2)" "unprognostic (1.42e-1)" "unprognostic (5.84e-2)" "unprognostic (3.33e-2)" "unprognostic (2.68e-2)" "unprognostic (4.06e-2)" "unprognostic (1.28e-1)" "unprognostic (2.81e-2)" "unprognostic (3.00e-2)" "unprognostic (1.56e-3)" "unprognostic (1.69e-1)" "unprognostic (3.61e-2)" "unprognostic (2.03e-3)" "unprognostic (1.11e-2)" "potential prognostic unfavorable (3.67e-4)" "unprognostic (2.80e-3)" "unprognostic (2.24e-2)" "unprognostic (1.46e-1)" "unprognostic (7.59e-2)" "unprognostic (3.62e-3)" "unprognostic (4.70e-3)" "unprognostic (3.00e-1)" "unprognostic (1.06e-2)" "unprognostic (2.48e-1)" "unprognostic (6.24e-2)" "unprognostic (1.81e-2)" "unprognostic (5.82e-2)" "unprognostic (5.34e-2)" SENP3 "DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1" ENSG00000161956 "SUMO specific peptidase 3" Q9H4L4 17 7561919-7571969 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Astrocytes: 27.1;Bergmann glia: 20.5;Brain excitatory neurons: 12.8;Brain inhibitory neurons: 12.8;Choroid plexus epithelial cells: 19.4;Ependymal cells: 10.2;Microglia: 15.7;Oligodendrocyte progenitor cells: 14.1;Oligodendrocytes: 18.4;Other brain neurons: 10.8" "Group enriched" "Detected in many" 7 "Ciliated cells: 19.4;Glial cells: 27.1;Neuronal cells: 12.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 11911195.1" "Tissue enhanced" "Detected in many" "bone marrow: 8908925.1;lung: 8999937.3" HPA060290 Supported Supported Nucleoplasm,Nucleoli Yes No "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 42: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 108 Nucleoli Nucleoplasm "HPA060290: " "unprognostic (2.34e-2)" "unprognostic (1.18e-1)" "unprognostic (2.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.69e-1)" "unprognostic (6.15e-2)" "unprognostic (2.31e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (2.21e-1)" "unprognostic (3.01e-2)" "potential prognostic favorable (4.06e-4)" "unprognostic (3.24e-2)" "unprognostic (9.04e-2)" "unprognostic (1.19e-3)" "unprognostic (4.48e-2)" "potential prognostic unfavorable (4.97e-4)" "unprognostic (3.44e-1)" "unprognostic (1.50e-1)" "unprognostic (2.54e-1)" "unprognostic (9.38e-2)" "unprognostic (9.79e-2)" "potential prognostic favorable (5.75e-4)" "unprognostic (1.73e-2)" "unprognostic (1.35e-2)" "unprognostic (6.12e-2)" "unprognostic (1.76e-1)" "unprognostic (1.86e-2)" "unprognostic (2.23e-1)" "unprognostic (3.03e-1)" "unprognostic (1.30e-2)" "unprognostic (1.61e-2)" SEPHS2 "SPS2, SPS2b" ENSG00000179918 "Selenophosphate synthetase 2" Q99611 16 30443631-30445874 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 377.1" "Cell type enhanced" "Detected in many" "Colonocytes: 213.0;Enterocytes: 373.2;Hepatocytes: 414.0" "Cell type enhanced" "Detected in many" "Enterocytes: 373.2;Hepatocytes: 414.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 9149429.2;Hepatocytes: 13322116.7;Large ducts: 3425864.8;Pancreas epithelial cells: 4735220.3;Proximal tubules: 10391503.6" "Group enriched" "Detected in all" "kidney: 20908381.4;liver: 30595153.9" HPA047931 Approved Approved Nucleoplasm No No 17000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 5 Nucleoplasm "HPA047931: " "unprognostic (2.90e-1)" "unprognostic (8.36e-3)" "unprognostic (4.98e-2)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (9.07e-2)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "potential prognostic favorable (1.69e-9)" "unprognostic (2.55e-3)" "unprognostic (1.99e-1)" "unprognostic (4.14e-2)" "unprognostic (4.05e-3)" "unprognostic (2.03e-1)" "unprognostic (1.58e-1)" "unprognostic (4.82e-3)" "unprognostic (7.59e-2)" "unprognostic (2.89e-1)" "unprognostic (2.05e-1)" "unprognostic (2.12e-2)" "unprognostic (2.77e-1)" "unprognostic (2.57e-2)" "unprognostic (5.02e-2)" "unprognostic (4.81e-2)" "unprognostic (8.53e-2)" "unprognostic (8.05e-2)" "unprognostic (1.07e-1)" "unprognostic (3.11e-2)" "unprognostic (1.68e-1)" SEPTIN10 "FLJ11619, SEPT10" ENSG00000186522 "Septin 10" Q9P0V9 2 109542799-109614143 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 342.9;Esophageal apical cells: 479.9;Late spermatids: 668.4;Urothelial cells: 288.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 479.9;Spermatogenic cell types: 668.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 242.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 3.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 16081208.1;Keratinocytes: 18955370.2" "Low tissue specificity" "Detected in all" HPA056304 Enhanced Supported "Actin filaments,Microtubules,Annulus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 72: Neuronal - Signal transduction" "Cluster 69: Urothelial cells - Basic cellular functions" 24 "Actin filaments" "Microtubules, Annulus" "HPA056304: " "unprognostic (2.21e-2)" "unprognostic (4.25e-2)" "unprognostic (2.22e-3)" "unprognostic (1.62e-1)" "unprognostic (1.55e-1)" "unprognostic (1.96e-1)" "unprognostic (1.66e-2)" "unprognostic (2.22e-1)" "unprognostic (1.24e-1)" "potential prognostic favorable (1.84e-7)" "unprognostic (3.09e-3)" "unprognostic (1.41e-1)" "unprognostic (4.07e-3)" "unprognostic (3.38e-3)" "unprognostic (1.50e-1)" "unprognostic (2.66e-1)" "unprognostic (2.03e-1)" "unprognostic (1.61e-1)" "unprognostic (1.50e-2)" "unprognostic (5.06e-3)" "potential prognostic unfavorable (7.58e-4)" "unprognostic (1.59e-1)" "unprognostic (5.34e-3)" "unprognostic (1.04e-1)" "unprognostic (9.02e-2)" "unprognostic (4.27e-2)" "unprognostic (2.96e-1)" "unprognostic (1.04e-1)" "unprognostic (3.17e-1)" SEPTIN11 "FLJ10849, SEPT11" ENSG00000138758 "Septin 11" Q9NVA2 4 76949751-77040384 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 462.5;Hepatic stellate cells: 387.3;Platelets: 517.8;Podocytes: 463.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Fibroblasts, Breast - Adipocytes (Breast), Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 228644586.2;Microglia and Neuropil: 248308508.5" "Tissue enriched" "Detected in all" "cerebral cortex: 183021626.1" "HPA003459, HPA005665" Approved Approved "Primary cilium,Cytosol,Mid piece,Principal piece,Annulus" NA NA 2100000 "Cluster 41: Basophils - Unknown function" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 43 Cytosol "Primary cilium, Mid piece, Principal piece, Annulus" "HPA003459: , HPA005665: " "unprognostic (1.12e-2)" "unprognostic (1.43e-1)" "unprognostic (1.26e-1)" "unprognostic (1.48e-2)" "unprognostic (3.04e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (3.31e-4)" "unprognostic (2.52e-1)" "potential prognostic unfavorable (5.52e-4)" "potential prognostic favorable (1.24e-6)" "unprognostic (7.20e-3)" "unprognostic (6.77e-2)" "potential prognostic unfavorable (3.71e-5)" "unprognostic (1.12e-1)" "unprognostic (1.16e-3)" "unprognostic (1.53e-1)" "unprognostic (1.37e-1)" "unprognostic (1.40e-2)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (6.86e-3)" "unprognostic (2.07e-1)" "unprognostic (1.11e-1)" "unprognostic (1.00e-1)" "unprognostic (1.91e-2)" "unprognostic (2.03e-3)" "unprognostic (1.18e-1)" "unprognostic (2.17e-1)" "unprognostic (3.89e-1)" "unprognostic (2.63e-1)" SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969443-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 253.5" "Cell type enhanced" "Detected in many" "Astrocytes: 21.9;Brain excitatory neurons: 55.5;Brain inhibitory neurons: 43.7;Choroid plexus epithelial cells: 18.8;Early spermatids: 30.3;Extravillous trophoblasts: 45.7;Late spermatids: 46.7;Melanocytes: 20.3;Oligodendrocyte progenitor cells: 22.2;Other brain neurons: 43.2;Pancreatic islet cells: 23.2;Retinal amacrine cells: 22.6;Retinal bipolar cells: 18.0;Retinal horizontal cells: 18.0" "Cell type enhanced" "Detected in many" "Neuronal cells: 55.5;Pancreatic islet cells: 23.2;Spermatogenic cell types: 46.7;Trophoblast cells: 45.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 51.5;Skin Cutaneous Melanoma (TCGA): 23.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 48.8" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 90482271.5;Microglia and Neuropil: 105796997.9;Neurons: 40125097.0" "Tissue enriched" "Detected in some" "cerebral cortex: 292901466.9" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments,Primary cilium" NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 35 "Plasma membrane, Actin filaments" "Nucleoplasm, Primary cilium" "CAB017633: , HPA003548: " "unprognostic (4.23e-2)" "unprognostic (2.96e-1)" "unprognostic (1.47e-1)" "unprognostic (1.16e-1)" "unprognostic (2.51e-2)" "potential prognostic favorable (5.41e-4)" "unprognostic (9.51e-2)" "unprognostic (3.94e-3)" "unprognostic (1.96e-2)" "unprognostic (1.81e-3)" "unprognostic (4.48e-2)" "unprognostic (3.74e-2)" "unprognostic (3.79e-1)" "unprognostic (4.40e-2)" "unprognostic (5.09e-3)" "unprognostic (3.54e-1)" "unprognostic (1.32e-2)" "unprognostic (1.12e-1)" "unprognostic (7.04e-2)" "unprognostic (8.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.88e-2)" "unprognostic (1.73e-1)" "unprognostic (1.41e-2)" "unprognostic (1.26e-1)" "unprognostic (1.15e-2)" SEPTIN6 "KIAA0128, MGC16619, MGC20339, SEP2, SEPT2, SEPT6" ENSG00000125354 "Septin 6" Q14141 X 119615724-119693370 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Host-virus interaction, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 215.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 280.0;B-cells: 262.5;cDC: 295.7;Hematopoietic stem cells: 396.4;Innate lymphoid cells: 312.9;Megakaryocyte-Erythroid progenitors: 245.8;NK-cells: 269.7;pDCs: 284.0;Platelets: 304.1;Sertoli cells: 476.5;T-cells: 343.1;Thymocytes: 521.7" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 476.5;T-cells: 521.7" "Cell type enhanced" "Detected in all" "leukocyte: 277.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Leukemia: 212.4;lymphoma: 198.6;Myeloma: 126.1;Neuroblastoma: 108.4" "Adrenal gland - Adrenal cortex cells, Breast - T-cells, Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen), Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 33112276.6" "Tissue enhanced" "Detected in many" "cerebral cortex: 65577767.3" "HPA003459, HPA005665" Supported Approved "Primary cilium,Cytosol,Mid piece,Principal piece" NA NA 2400000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 44 Cytosol "Primary cilium, Mid piece, Principal piece" "HPA003459: , HPA005665: " "unprognostic (5.34e-3)" "unprognostic (1.03e-1)" "unprognostic (1.89e-1)" "unprognostic (1.28e-1)" "unprognostic (6.48e-2)" "unprognostic (1.56e-1)" "unprognostic (2.26e-1)" "unprognostic (1.98e-1)" "unprognostic (5.78e-2)" "unprognostic (2.26e-3)" "unprognostic (4.38e-2)" "unprognostic (1.39e-1)" "unprognostic (1.80e-1)" "unprognostic (4.26e-2)" "unprognostic (3.16e-2)" "unprognostic (5.89e-2)" "unprognostic (2.00e-1)" "unprognostic (8.85e-2)" "unprognostic (3.77e-1)" "unprognostic (1.68e-1)" "unprognostic (1.23e-2)" "unprognostic (3.21e-2)" "unprognostic (8.85e-2)" "unprognostic (2.76e-2)" "unprognostic (1.16e-1)" "unprognostic (1.81e-1)" "unprognostic (5.72e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" SEPTIN8 "KIAA0202, SEP2, SEPT8" ENSG00000164402 "Septin 8" Q92599 5 132750819-132807241 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "brain: 749.6" "Cell type enhanced" "Detected in many" "Bergmann glia: 118.6;Müller glia: 123.2;Oligodendrocyte progenitor cells: 107.7;Oligodendrocytes: 184.7;Retinal horizontal cells: 152.3;Retinal pigment epithelial cells: 89.5" "Cell type enhanced" "Detected in many" "Glial cells: 184.7;Neuronal cells: 152.3" "Cell type enhanced" "Detected in all" "oligodendrocyte: 259.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Fibroblasts, Skin - Keratinocyte (other), Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 224111940.1;Microglia and Neuropil: 123722752.3" "Tissue enriched" "Detected in all" "cerebral cortex: 362442013.3" "HPA005665, HPA036534" Enhanced Approved "Actin filaments,Primary cilium,Cytosol,Mid piece,Principal piece,Annulus" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 11: Muller glia cells - Retinal homeostasis" 34 Cytosol "Actin filaments, Primary cilium, Mid piece, Principal piece, Annulus" "HPA005665: , HPA036534: " "potential prognostic favorable (3.19e-4)" "unprognostic (3.58e-2)" "unprognostic (2.38e-2)" "unprognostic (2.85e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" "unprognostic (3.46e-2)" "unprognostic (2.77e-1)" "unprognostic (6.89e-3)" "potential prognostic favorable (1.28e-5)" "unprognostic (5.19e-2)" "unprognostic (9.14e-2)" "unprognostic (1.85e-2)" "unprognostic (1.81e-2)" "unprognostic (7.81e-2)" "unprognostic (3.06e-2)" "unprognostic (3.65e-2)" "unprognostic (5.20e-3)" "unprognostic (5.65e-3)" "unprognostic (6.54e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (9.42e-2)" "unprognostic (1.02e-1)" "unprognostic (3.58e-2)" "unprognostic (5.90e-2)" "unprognostic (2.04e-1)" "unprognostic (2.10e-2)" "unprognostic (3.26e-1)" SEPTIN9 "AF17q25, KIAA0991, MSF, MSF1, PNUTL4, SEPT9, SeptD1" ENSG00000184640 "Septin 9" Q9UHD8 17 77280569-77500596 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 517.5" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 219.7;leukocyte: 231.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 173209939.6" "HPA042564, HPA050627" Approved Enhanced "Actin filaments,Microtubules,Cytokinetic bridge,Primary cilium" Yes No 160000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 44: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 69: Urothelial cells - Basic cellular functions" 46 "Actin filaments" "Microtubules, Cytokinetic bridge, Primary cilium" "HPA042564: , HPA050627: " "unprognostic (2.63e-2)" "unprognostic (2.15e-1)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (4.39e-2)" "unprognostic (1.14e-1)" "unprognostic (3.04e-2)" "unprognostic (3.86e-2)" "unprognostic (6.43e-2)" "unprognostic (1.60e-2)" "potential prognostic favorable (2.14e-4)" "unprognostic (2.76e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (3.09e-6)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (3.53e-4)" "unprognostic (1.08e-3)" "unprognostic (8.76e-2)" "unprognostic (8.48e-2)" "unprognostic (5.40e-2)" "unprognostic (5.08e-2)" "unprognostic (5.51e-3)" "unprognostic (1.89e-1)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "unprognostic (4.73e-2)" "unprognostic (3.39e-1)" "unprognostic (4.80e-2)" "unprognostic (7.35e-2)" "unprognostic (1.05e-1)" SERPINB1 "EI, ELANH2, LEI, MNEI, PI2" ENSG00000021355 "Serpin family B member 1" P30740 6 2832332-2841959 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 440.9;esophagus: 497.6" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 10956.9;Esophageal suprabasal cells: 3640.8;Neutrophil progenitors: 1114.7;Neutrophils: 1391.7;Pancreatic acinar cells: 2078.8" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 10956.9;Suprabasal cells: 3640.8" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 50.1;choroid plexus epithelial cell: 19.8;endothelial cell: 66.7;ependymal cell: 22.4;fibroblast: 32.4;leukocyte: 49.3;oligodendrocyte: 23.0;pericyte: 52.0;vascular associated smooth muscle cell: 28.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 496799006.8" "Tissue enhanced" "Detected in all" "bone marrow: 703854924.0" "HPA018871, HPA018882, HPA052642" Enhanced Supported "Cytoplasmic bodies" "Secreted to blood" "Enzyme inhibitor" NA NA 26000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 85: Squamous epithelial cells - Keratinization" 2 "Cytoplasmic bodies" "HPA018871: , HPA018882: , HPA052642: " "unprognostic (8.16e-2)" "unprognostic (1.34e-2)" "unprognostic (1.11e-1)" "unprognostic (5.15e-2)" "unprognostic (4.57e-2)" "unprognostic (8.67e-2)" "potential prognostic unfavorable (1.00e-3)" "unprognostic (1.92e-2)" "unprognostic (5.95e-2)" "unprognostic (7.81e-3)" "potential prognostic favorable (2.04e-4)" "unprognostic (4.27e-2)" "unprognostic (4.48e-2)" "unprognostic (1.61e-3)" "unprognostic (6.81e-3)" "unprognostic (1.33e-1)" "unprognostic (1.38e-2)" "unprognostic (1.74e-2)" "unprognostic (5.42e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "potential prognostic unfavorable (3.95e-4)" "unprognostic (2.20e-1)" "unprognostic (5.20e-2)" "unprognostic (2.10e-2)" "unprognostic (5.45e-2)" "unprognostic (1.45e-1)" "unprognostic (3.03e-1)" "unprognostic (6.24e-2)" "unprognostic (2.21e-1)" "unprognostic (4.21e-2)" SERPINH1 "CBP1, CBP2, HSP47, SERPINH2" ENSG00000149257 "Serpin family H member 1" P50454 11 75562056-75572783 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 254.6;Decidual stromal cells: 560.8;Endometrial stromal cells: 208.6;Epididymal efferent duct absorptive cells: 307.1;Extravillous trophoblasts: 477.3;Fibroblasts: 193.9;Hepatic stellate cells: 445.4;Migrating cytotrophoblasts: 247.5;Ovarian stromal cells: 200.0;Pancreatic duct cells: 236.0;Smooth muscle cells: 208.7" "Cell type enhanced" "Detected in all" "Stellate cells: 445.4;Stromal cells: 560.8;Trophoblast cells: 477.3" "Cell type enhanced" "Detected in many" "endothelial cell: 100.0;fibroblast: 57.2;pericyte: 75.1;vascular associated smooth muscle cell: 62.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 318617262.1" "Low tissue specificity" "Detected in all" "CAB004441, HPA029198" Supported Supported "Endoplasmic reticulum" "Intracellular and membrane" Other NA Yes 780000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 5: Rhabdoid - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 54 "Endoplasmic reticulum" "CAB004441: , HPA029198: " "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (1.39e-5)" "unprognostic (1.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.54e-2)" "unprognostic (7.24e-3)" "unprognostic (1.86e-3)" "unprognostic (6.59e-2)" "unprognostic (1.64e-3)" "unprognostic (5.95e-3)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.95e-3)" "unprognostic (4.08e-2)" "validated prognostic unfavorable (1.93e-4)" "validated prognostic unfavorable (9.64e-6)" "unprognostic (1.59e-2)" "unprognostic (6.40e-2)" "unprognostic (1.96e-1)" "unprognostic (1.09e-1)" "unprognostic (2.35e-2)" "unprognostic (7.49e-2)" "unprognostic (7.23e-3)" "unprognostic (2.16e-1)" "unprognostic (2.06e-1)" "unprognostic (1.09e-2)" "unprognostic (1.72e-2)" "unprognostic (2.83e-1)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" SET "2PP2A, IGAAD, IPP2A2, PHAPII, TAF-I, TAF-IBETA" ENSG00000119335 "SET nuclear proto-oncogene" Q01105 9 128683424-128696400 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Chaperone, DNA-binding" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "CAB005232, HPA063683" Supported Enhanced "Nucleoplasm,Lipid droplets" NA NA 1700000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 17: Non-specific - RNA processing" 65 Nucleoplasm "Lipid droplets" "CAB005232: , HPA063683: " "unprognostic (1.18e-3)" "unprognostic (2.49e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-1)" "unprognostic (2.10e-3)" "unprognostic (2.86e-2)" "unprognostic (1.30e-2)" "unprognostic (1.40e-2)" "unprognostic (1.53e-1)" "potential prognostic favorable (2.55e-6)" "unprognostic (4.25e-3)" "unprognostic (1.95e-1)" "validated prognostic unfavorable (1.66e-4)" "validated prognostic unfavorable (3.85e-6)" "unprognostic (1.17e-2)" "unprognostic (3.54e-3)" "unprognostic (2.19e-1)" "unprognostic (6.50e-3)" "unprognostic (4.03e-1)" "unprognostic (5.08e-2)" "unprognostic (1.05e-2)" "unprognostic (2.28e-1)" "unprognostic (4.08e-2)" "unprognostic (1.26e-1)" "unprognostic (2.55e-1)" "unprognostic (1.22e-1)" "unprognostic (1.21e-2)" "unprognostic (2.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.79e-2)" SETD1A "KIAA0339, KMT2F, Set1, SET1A" ENSG00000099381 "SET domain containing 1A, histone lysine methyltransferase" O15047 16 30957754-30984664 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, RNA-binding, Transferase" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "fallopian tube: 5287648.9;lymphoid tissue: 4858662.6" "HPA020646, HPA058376" Enhanced Supported "Nuclear speckles" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 36 "Nuclear speckles" "HPA020646: , HPA058376: " "unprognostic (2.92e-1)" "unprognostic (7.00e-2)" "unprognostic (3.83e-1)" "unprognostic (4.38e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-1)" "unprognostic (2.56e-1)" "unprognostic (2.55e-1)" "unprognostic (5.99e-2)" "unprognostic (2.05e-1)" "unprognostic (3.73e-2)" "unprognostic (3.62e-2)" "unprognostic (1.11e-1)" "unprognostic (2.14e-3)" "unprognostic (3.21e-2)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (3.40e-1)" "unprognostic (1.15e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" "unprognostic (6.14e-2)" "unprognostic (6.77e-3)" "unprognostic (8.20e-2)" "unprognostic (2.75e-2)" "unprognostic (2.19e-1)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" "unprognostic (2.13e-1)" "unprognostic (4.99e-2)" "unprognostic (2.85e-2)" SETD5 "FLJ10707, SETD5A" ENSG00000168137 "SET domain containing 5" Q9C0A6 3 9397615-9479240 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Autism, Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 285 "Granulosa cells: 28499.7" "Not detected" "Not detected" "CAB017093, HPA035574" Approved Enhanced Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 18: Adrenal cortex cells - Steroidogensis" 4 Nucleoplasm Cytosol "CAB017093: , HPA035574: " "unprognostic (2.66e-2)" "unprognostic (8.81e-3)" "unprognostic (1.79e-2)" "unprognostic (6.52e-2)" "unprognostic (4.70e-2)" "unprognostic (2.40e-2)" "unprognostic (1.14e-1)" "unprognostic (2.26e-2)" "unprognostic (1.30e-1)" "unprognostic (3.49e-3)" "unprognostic (2.50e-1)" "unprognostic (1.78e-2)" "unprognostic (2.14e-1)" "unprognostic (3.92e-3)" "unprognostic (4.10e-1)" "unprognostic (2.63e-1)" "unprognostic (3.41e-2)" "unprognostic (1.40e-1)" "unprognostic (2.20e-2)" "unprognostic (1.60e-1)" "unprognostic (1.65e-1)" "unprognostic (2.55e-1)" "unprognostic (9.03e-3)" "unprognostic (2.08e-2)" "unprognostic (2.28e-3)" "unprognostic (1.41e-2)" "unprognostic (2.97e-1)" "unprognostic (3.98e-2)" "unprognostic (1.72e-1)" "unprognostic (3.42e-2)" "unprognostic (1.58e-1)" SETD6 FLJ21148 ENSG00000103037 "SET domain containing 6, protein lysine methyltransferase" Q8TBK2 16 58515479-58523842 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 618 "salivary gland: 61837.0" "HPA041481, HPA053546" Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm Cytosol "HPA041481: , HPA053546: " "unprognostic (1.73e-1)" "unprognostic (1.34e-1)" "unprognostic (2.81e-1)" "unprognostic (3.26e-1)" "unprognostic (1.90e-1)" "unprognostic (7.77e-2)" "unprognostic (6.76e-2)" "unprognostic (3.66e-3)" "unprognostic (6.33e-2)" "unprognostic (1.26e-1)" "potential prognostic unfavorable (3.33e-5)" "unprognostic (4.24e-2)" "unprognostic (1.95e-2)" "unprognostic (2.80e-2)" "unprognostic (3.83e-1)" "unprognostic (6.94e-2)" "unprognostic (2.93e-1)" "unprognostic (3.33e-1)" "unprognostic (2.28e-2)" "unprognostic (4.92e-2)" "unprognostic (3.77e-1)" "unprognostic (3.64e-2)" "unprognostic (4.42e-2)" "unprognostic (1.77e-2)" "unprognostic (4.65e-1)" "unprognostic (1.40e-1)" "unprognostic (1.20e-3)" "unprognostic (2.35e-1)" "unprognostic (3.71e-2)" "unprognostic (1.71e-2)" "unprognostic (3.16e-2)" SETD7 "KIAA1717, KMT7, SET7, SET7/9, Set9" ENSG00000145391 "SET domain containing 7, histone lysine methyltransferase" Q8WTS6 4 139495941-139606699 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 129.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 4995009.9;Skeletal myofibers: 5526348.7" "Tissue enhanced" "Detected in all" "pancreas: 68915008.6" HPA058111 Enhanced Enhanced "Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 45 "Nucleoli, Nucleoli rim" "Mitotic chromosome" "HPA058111: " "unprognostic (3.97e-2)" "unprognostic (6.04e-3)" "unprognostic (3.10e-1)" "unprognostic (3.61e-3)" "unprognostic (1.56e-1)" "unprognostic (8.33e-2)" "unprognostic (2.85e-1)" "unprognostic (2.72e-1)" "unprognostic (4.11e-2)" "unprognostic (2.70e-2)" "potential prognostic favorable (1.41e-4)" "unprognostic (2.47e-3)" "unprognostic (1.67e-1)" "unprognostic (6.89e-2)" "unprognostic (2.45e-3)" "unprognostic (4.42e-2)" "unprognostic (2.03e-2)" "unprognostic (1.98e-1)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" "unprognostic (4.79e-2)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (2.21e-1)" "unprognostic (2.06e-2)" "unprognostic (1.06e-3)" "unprognostic (1.36e-1)" "unprognostic (3.07e-2)" "unprognostic (1.15e-1)" SETDB1 "ESET, KG1T, KIAA0067, KMT1E, TDRD21" ENSG00000143379 "SET domain bifurcated histone lysine methyltransferase 1" Q15047 1 150926263-150964744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 866567.4" "Group enriched" "Detected in some" "bone marrow: 952937.7;fallopian tube: 658368.7;lymphoid tissue: 481153.7;ovary: 308991.0" "HPA018142, HPA058484" Uncertain Supported Nucleoplasm,Vesicles Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 48 Nucleoplasm Vesicles "HPA018142: , HPA058484: " "unprognostic (8.89e-2)" "unprognostic (1.40e-1)" "unprognostic (3.85e-2)" "unprognostic (1.39e-2)" "unprognostic (2.25e-1)" "unprognostic (2.40e-1)" "unprognostic (2.20e-1)" "potential prognostic favorable (7.02e-4)" "unprognostic (2.71e-1)" "unprognostic (1.41e-3)" "potential prognostic favorable (9.39e-6)" "unprognostic (6.63e-3)" "unprognostic (9.03e-2)" "unprognostic (2.50e-3)" "unprognostic (5.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.04e-2)" "unprognostic (1.79e-1)" "unprognostic (9.85e-2)" "unprognostic (1.23e-1)" "unprognostic (1.95e-1)" "unprognostic (4.32e-2)" "unprognostic (1.39e-1)" "unprognostic (4.59e-2)" "unprognostic (1.51e-2)" "unprognostic (1.86e-1)" "unprognostic (2.68e-2)" "unprognostic (3.14e-1)" "unprognostic (1.26e-1)" "unprognostic (5.71e-2)" "unprognostic (5.90e-2)" SETDB2 "C13orf4, CLLD8, CLLL8, KMT1F" ENSG00000136169 "SET domain bifurcated histone lysine methyltransferase 2" Q96T68 13 49444274-49495003 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Chromatin regulator, Developmental protein, Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 109.5;Renal collecting duct intercalated cells: 106.3;Sertoli cells: 125.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 3374 "Granulosa cells: 337432.9" "Group enriched" "Detected in some" 341 "intestine: 40746.6;ovary: 27461.1" "CAB012190, HPA071677" Approved Supported Nucleoplasm,Cytosol No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 19: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 Nucleoplasm Cytosol "CAB012190: , HPA071677: " "unprognostic (5.67e-2)" "unprognostic (3.94e-1)" "unprognostic (1.47e-1)" "unprognostic (9.66e-2)" "unprognostic (2.98e-1)" "unprognostic (3.50e-2)" "unprognostic (1.15e-1)" "unprognostic (4.06e-2)" "unprognostic (3.54e-2)" "unprognostic (1.63e-1)" "potential prognostic favorable (9.24e-6)" "unprognostic (4.05e-3)" "potential prognostic favorable (7.32e-7)" "unprognostic (6.40e-2)" "unprognostic (4.65e-2)" "potential prognostic favorable (7.41e-4)" "unprognostic (1.61e-1)" "unprognostic (1.72e-2)" "unprognostic (1.26e-1)" "unprognostic (3.39e-2)" "unprognostic (7.12e-2)" "unprognostic (2.89e-3)" "unprognostic (4.35e-2)" "unprognostic (3.42e-1)" "unprognostic (6.00e-2)" "unprognostic (5.77e-3)" "unprognostic (2.76e-1)" "unprognostic (2.30e-1)" "unprognostic (1.78e-1)" "unprognostic (3.25e-3)" "unprognostic (3.76e-2)" SETSIP SETP18 ENSG00000230667 "SET like protein" P0DME0 1 92074533-92075411 "Predicted intracellular proteins" "Differentiation, Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Early spermatids: 1.6;Late primary spermatocytes: 1.9" "Cell type enhanced" "Detected in single" "Spermatogenic cell types: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA063683 Approved Supported "Nucleoplasm,Lipid droplets" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Nucleoplasm "Lipid droplets" "HPA063683: " "potential prognostic unfavorable (8.43e-4)" SETX "ALS4, AOA2, KIAA0625, SCAR1, Sen1, STEX" ENSG00000107290 Senataxin Q7Z333 9 132261356-132354986 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Differentiation, DNA damage, DNA recombination, DNA repair, Neurogenesis, Spermatogenesis" "Helicase, Hydrolase" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in single" 7402 "lymphoid tissue: 740162.1" "HPA024105, HPA057269" Approved Supported "Nucleoplasm,Cytokinetic bridge" Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 69: Urothelial cells - Basic cellular functions" 10 Nucleoplasm "Cytokinetic bridge" "HPA024105: , HPA057269: " "unprognostic (3.28e-1)" "unprognostic (6.30e-2)" "unprognostic (3.35e-3)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" "unprognostic (8.03e-3)" "unprognostic (1.61e-1)" "unprognostic (7.06e-3)" "unprognostic (3.90e-2)" "unprognostic (9.47e-3)" "potential prognostic favorable (5.60e-6)" "unprognostic (2.85e-3)" "unprognostic (2.82e-1)" "unprognostic (1.69e-1)" "unprognostic (2.06e-1)" "unprognostic (1.95e-1)" "unprognostic (5.08e-2)" "unprognostic (6.06e-2)" "unprognostic (1.47e-2)" "unprognostic (6.92e-3)" "unprognostic (4.25e-2)" "unprognostic (5.52e-2)" "unprognostic (5.18e-2)" "unprognostic (3.15e-1)" "unprognostic (4.55e-3)" "unprognostic (5.96e-2)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (3.14e-1)" "unprognostic (1.76e-2)" "unprognostic (2.02e-1)" SEZ6L ENSG00000100095 "Seizure related 6 homolog like" Q9BYH1 22 26169462-26383597 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 46.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 202.1;Brain excitatory neurons: 324.8;Brain inhibitory neurons: 170.8;Corticotrophs: 92.8;Gonadotrophs: 212.8;Oligodendrocyte progenitor cells: 849.9;Other brain neurons: 238.2;Pancreatic islet cells: 183.2;Retinal amacrine cells: 170.0;Retinal horizontal cells: 122.2" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 202.1;Glial cells: 849.9;Neuronal cells: 324.8;Pancreatic islet cells: 183.2;Pituitary endocrine cells: 212.8" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in some" 4 "Glioblastoma Multiforme (TCGA): 26.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "intermediate monocyte: 5.9;myeloid DC: 5.7;non-classical monocyte: 5.4" "Group enriched" "Detected in many" 58 "dendritic cells: 5.7;monocytes: 5.9" "Group enriched" "Detected in some" 5 "Bone cancer: 23.7;lung cancer: 8.1;Neuroblastoma: 23.5" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 7179603.8;Large ducts: 5641567.2;Microglia and Neuropil: 8180302.8;Neurons: 8255593.3" "Tissue enriched" "Detected in single" 67613 "cerebral cortex: 6761265.2" HPA045135 Approved Vesicles NA NA 1500000 "Cluster 40: Monocytes - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 1: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "HPA045135: " "unprognostic (6.00e-2)" "unprognostic (1.76e-1)" "unprognostic (1.55e-2)" "unprognostic (3.39e-2)" "unprognostic (1.30e-1)" "unprognostic (1.94e-1)" "potential prognostic favorable (8.40e-5)" "unprognostic (1.72e-1)" "unprognostic (2.68e-1)" "unprognostic (1.77e-1)" SF3A1 "Prp21, PRPF21, SAP114, SF3a120" ENSG00000099995 "Splicing factor 3a subunit 1" Q15459 22 30331988-30356919 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 179.7;Neutrophils: 132.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 179.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA000690, HPA030083" Enhanced Enhanced "Nucleoplasm,Nuclear speckles" NA NA 28000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 299 "Nucleoplasm, Nuclear speckles" "HPA000690: , HPA030083: " "unprognostic (6.11e-3)" "unprognostic (1.21e-1)" "unprognostic (2.26e-1)" "unprognostic (1.63e-2)" "unprognostic (2.26e-1)" "unprognostic (7.38e-2)" "unprognostic (2.21e-2)" "unprognostic (2.51e-1)" "unprognostic (2.85e-1)" "unprognostic (6.11e-3)" "validated prognostic favorable (4.12e-8)" "validated prognostic favorable (4.01e-6)" "unprognostic (3.80e-2)" "potential prognostic unfavorable (9.79e-4)" "unprognostic (4.55e-3)" "unprognostic (1.40e-1)" "unprognostic (1.65e-1)" "unprognostic (9.21e-2)" "unprognostic (1.30e-2)" "unprognostic (3.53e-2)" "unprognostic (3.30e-2)" "unprognostic (5.58e-2)" "unprognostic (9.72e-2)" "unprognostic (3.19e-1)" "unprognostic (1.53e-1)" "unprognostic (1.19e-1)" "unprognostic (5.99e-2)" "unprognostic (4.62e-1)" "unprognostic (5.13e-1)" "unprognostic (1.61e-2)" "unprognostic (1.72e-2)" SF3B3 "KIAA0017, RSE1, SAP130, SF3b130" ENSG00000189091 "Splicing factor 3b subunit 3" Q15393 16 70523791-70577670 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Esophageal apical cells: 772.0" "Cell type enriched" "Detected in all" 5 "Apical squamous epithelial cells: 772.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA041134, HPA042986" Supported Supported "Nucleoplasm,Nucleoli,Nucleoli rim" No No 77000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 84: Apical squamous epithelium - Cornification" 231 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA041134: , HPA042986: " "unprognostic (2.06e-1)" "unprognostic (8.95e-2)" "unprognostic (1.49e-1)" "unprognostic (2.73e-3)" "unprognostic (6.23e-2)" "unprognostic (9.90e-2)" "unprognostic (1.88e-1)" "unprognostic (2.83e-2)" "unprognostic (4.44e-1)" "unprognostic (6.08e-2)" "potential prognostic favorable (2.67e-5)" "unprognostic (3.59e-2)" "unprognostic (2.54e-1)" "unprognostic (5.36e-3)" "unprognostic (7.46e-2)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (7.57e-4)" "unprognostic (1.91e-1)" "unprognostic (2.29e-1)" "unprognostic (4.98e-2)" "unprognostic (2.77e-2)" "unprognostic (1.91e-3)" "unprognostic (1.75e-2)" "unprognostic (1.38e-1)" "unprognostic (1.00e-2)" "unprognostic (2.58e-1)" "unprognostic (1.02e-1)" "unprognostic (2.17e-1)" "unprognostic (1.62e-1)" "unprognostic (5.56e-3)" "unprognostic (1.86e-1)" SFN YWHAS ENSG00000175793 Stratifin P31947 1 26863149-26864456 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2404.7;skin 1: 1183.0;vagina: 678.0" "Group enriched" "Detected in many" 7 "Basal keratinocytes: 6517.9;Esophageal apical cells: 8730.6;Esophageal basal cells: 4503.0;Esophageal suprabasal cells: 10490.6;Ocular epithelial cells: 3989.3;Suprabasal keratinocytes: 10595.6" "Group enriched" "Detected in many" 7 "Apical squamous epithelial cells: 8730.6;Barrier epithelial cells: 3989.3;Basal cells: 6517.9;Suprabasal cells: 10595.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 3201.7;Head and Neck Squamous Cell Carcinoma (TCGA): 3646.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 17 "basophil: 5.9" "Lineage enriched" "Detected in single" 17 "granulocytes: 5.9" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 1337.8;head and neck cancer: 928.9" "Breast - Breast myoepithelial cells, Colon - Colon enterocytes, Stomach - Gastric mucous cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 6.8" "Cell type enriched" "Detected in some" "Keratinocytes: 1451440191.2" "Tissue enriched" "Detected in all" "skin: 1753647250.0" "CAB006268, HPA011105, CAB040552, HPA061603" Enhanced Supported "Nucleoplasm,Nucleoli rim,Cytosol,Mid piece" "Secreted in other tissues" "No annotated function" NA Yes 35000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 85: Squamous epithelial cells - Keratinization" 288 Cytosol "Nucleoplasm, Nucleoli rim, Mid piece" "CAB006268: , CAB040552: , HPA011105: , HPA061603: " "unprognostic (7.12e-2)" "unprognostic (4.62e-2)" "unprognostic (2.55e-3)" "unprognostic (6.27e-2)" "unprognostic (1.99e-1)" "unprognostic (3.80e-1)" "unprognostic (5.77e-3)" "unprognostic (1.07e-1)" "unprognostic (2.42e-1)" "unprognostic (1.82e-2)" "potential prognostic unfavorable (8.44e-5)" "unprognostic (5.73e-3)" "unprognostic (3.03e-2)" "validated prognostic unfavorable (1.03e-5)" "validated prognostic unfavorable (1.28e-6)" "potential prognostic unfavorable (2.53e-4)" "unprognostic (1.09e-2)" "unprognostic (2.34e-2)" "unprognostic (7.73e-2)" "unprognostic (1.45e-1)" "unprognostic (9.69e-2)" "unprognostic (2.18e-3)" "unprognostic (3.09e-1)" "unprognostic (2.75e-1)" "unprognostic (6.31e-3)" "unprognostic (1.48e-1)" "unprognostic (1.05e-1)" "unprognostic (2.31e-2)" "unprognostic (4.10e-1)" "unprognostic (8.75e-2)" "unprognostic (3.19e-2)" SFR1 "bA373N18.1, C10orf78, FLJ41960, MEI5, MEIR5" ENSG00000156384 "SWI5 dependent homologous recombination repair protein 1" Q86XK3 10 104122058-104126385 "Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Early primary spermatocytes: 252.3" "Cell type enriched" "Detected in all" 6 "Spermatogenic cell types: 252.3" "Cell type enhanced" "Detected in many" "oligodendrocyte: 21.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 19755.3" "Not detected" "Not detected" HPA039617 Uncertain Supported "Nucleoplasm,Nucleoli rim,Centrosome" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 3: Early primary spermatocytes - Early meiosis" 11 "Nucleoli rim" "Nucleoplasm, Centrosome" "HPA039617: " "unprognostic (1.49e-1)" "unprognostic (2.08e-1)" "unprognostic (1.50e-1)" "unprognostic (1.93e-1)" "unprognostic (1.35e-1)" "unprognostic (5.32e-2)" "unprognostic (1.98e-2)" "unprognostic (3.19e-2)" "unprognostic (2.99e-2)" "potential prognostic favorable (3.49e-7)" "unprognostic (2.62e-1)" "unprognostic (1.79e-1)" "potential prognostic unfavorable (3.12e-6)" "unprognostic (2.58e-2)" "unprognostic (1.34e-2)" "unprognostic (5.05e-3)" "unprognostic (2.14e-1)" "unprognostic (2.53e-1)" "unprognostic (2.95e-2)" "unprognostic (1.95e-3)" "potential prognostic unfavorable (5.88e-4)" "unprognostic (1.37e-1)" "validated prognostic favorable (4.69e-5)" "validated prognostic favorable (8.04e-4)" "unprognostic (1.35e-1)" "unprognostic (1.14e-2)" "unprognostic (4.82e-2)" "unprognostic (4.60e-3)" "unprognostic (1.59e-2)" SFXN3 "SFX3, SLC56A3" ENSG00000107819 "Sideroflexin 3" Q9BWM7 10 101031234-101041241 "Metabolic proteins, Predicted membrane proteins" "Amino-acid transport, One-carbon metabolism, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 60.2;Enterocytes: 119.9;Extravillous trophoblasts: 63.7;Late spermatids: 275.1;Respiratory ciliated cells: 56.4" "Cell type enhanced" "Detected in many" "Enterocytes: 119.9;Spermatogenic cell types: 275.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "cerebral cortex: 92233579.3" "HPA008028, HPA048105" Approved Enhanced Mitochondria NA NA 5300 "Cluster 42: Non-specific - Vesicular transport" "Cluster 77: Intestine - Digestion" "Cluster 34: Non-specific - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 1: Enterocytes - Absorption and Digestion" 49 Mitochondria "HPA008028: , HPA048105: " "unprognostic (1.71e-1)" "unprognostic (9.85e-3)" "unprognostic (3.92e-1)" "unprognostic (1.02e-2)" "unprognostic (3.37e-3)" "unprognostic (4.15e-2)" "unprognostic (5.63e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (5.34e-4)" "unprognostic (2.73e-1)" "potential prognostic favorable (3.67e-5)" "unprognostic (2.44e-1)" "unprognostic (4.81e-1)" "potential prognostic unfavorable (6.24e-4)" "unprognostic (3.62e-1)" "unprognostic (6.97e-2)" "unprognostic (4.97e-3)" "unprognostic (1.46e-2)" "unprognostic (8.06e-2)" "potential prognostic unfavorable (6.22e-4)" "unprognostic (4.27e-3)" "unprognostic (1.70e-3)" "unprognostic (1.57e-2)" "unprognostic (1.09e-1)" "unprognostic (3.31e-1)" "unprognostic (1.68e-2)" "unprognostic (1.58e-1)" "unprognostic (4.11e-1)" "unprognostic (5.34e-2)" "unprognostic (1.57e-1)" "unprognostic (5.37e-2)" SFXN4 SLC56A4 ENSG00000183605 "Sideroflexin 4" Q6P4A7 10 119140767-119165714 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 128.4;Myonuclei: 193.5" "Cell type enhanced" "Detected in many" "Myocytes: 193.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 95046686.7" "Tissue enriched" "Detected in many" "bone marrow: 18412087.1" "HPA018028, HPA020872" Approved Approved Nucleoplasm,Vesicles,Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Myocytes - Oxidative muscle function" 33 "Nucleoplasm, Mitochondria" Vesicles "HPA018028: , HPA020872: " "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "unprognostic (9.87e-2)" "unprognostic (2.41e-1)" "unprognostic (3.62e-1)" "unprognostic (1.58e-1)" "unprognostic (6.40e-2)" "unprognostic (7.00e-3)" "unprognostic (4.88e-2)" "potential prognostic unfavorable (8.90e-4)" "potential prognostic favorable (9.38e-8)" "unprognostic (6.62e-2)" "unprognostic (6.83e-2)" "unprognostic (2.13e-2)" "unprognostic (1.67e-1)" "unprognostic (4.68e-2)" "unprognostic (1.48e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (9.25e-2)" "unprognostic (3.01e-3)" "unprognostic (3.63e-2)" "unprognostic (1.09e-1)" "unprognostic (1.93e-2)" "unprognostic (5.47e-3)" "unprognostic (9.23e-3)" "unprognostic (4.54e-2)" "unprognostic (1.81e-2)" "unprognostic (3.11e-1)" "unprognostic (2.15e-3)" "unprognostic (2.19e-1)" SGCB "A3b, LGMD2E, SGC" ENSG00000163069 "Sarcoglycan beta" Q16585 4 52020706-52038299 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 98.9" "Cell type enhanced" "Detected in many" "Late spermatids: 300.1;Schwann cells: 122.1;Thymic myoid cells: 159.1" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 300.1;Stromal cells: 159.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 100.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 18501529.0;Cardiomyocytes: 30037542.5;Skeletal myofibers: 17219232.8" "Tissue enhanced" "Detected in many" "heart muscle: 44001776.6" "HPA011422, HPA058656" Enhanced Approved Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 32 Cytosol "HPA011422: , HPA058656: " "unprognostic (1.63e-1)" "unprognostic (3.94e-2)" "unprognostic (1.05e-1)" "unprognostic (1.39e-1)" "unprognostic (5.38e-2)" "unprognostic (1.76e-1)" "unprognostic (3.16e-1)" "unprognostic (3.96e-2)" "unprognostic (2.00e-2)" "unprognostic (2.70e-1)" "validated prognostic favorable (2.23e-11)" "validated prognostic favorable (4.38e-4)" "unprognostic (1.76e-3)" "unprognostic (1.48e-3)" "unprognostic (2.28e-2)" "unprognostic (3.50e-2)" "unprognostic (2.20e-2)" "unprognostic (8.81e-3)" "unprognostic (2.83e-1)" "unprognostic (1.98e-1)" "unprognostic (2.77e-3)" "unprognostic (6.67e-2)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (2.37e-1)" "unprognostic (5.63e-2)" "unprognostic (1.06e-1)" "unprognostic (2.58e-2)" "unprognostic (5.69e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 115.3" "Cell type enhanced" "Detected in many" "Corticotrophs: 263.4;Gonadotrophs: 327.0;Lactotrophs: 318.4;Sertoli cells: 283.6;Thyrotrophs: 362.5" "Cell type enhanced" "Detected in many" "Pituitary endocrine cells: 362.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.5;naive B-cell: 6.7" "Group enriched" "Detected in many" 4 "B-cells: 6.7;T-cells: 2.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adrenal gland - Adrenal cortex cells, Liver - Hepatic stellate cells, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 13646183.0" "Tissue enhanced" "Detected in many" "blood vessel: 12581867.4;intestine: 10667108.2" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 120000 "Cluster 34: B-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: " "unprognostic (3.28e-2)" "unprognostic (2.66e-3)" "unprognostic (1.55e-1)" "unprognostic (4.71e-2)" "unprognostic (9.55e-3)" "unprognostic (2.64e-1)" "unprognostic (7.49e-2)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (4.74e-4)" "unprognostic (4.71e-2)" "potential prognostic favorable (1.56e-4)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (1.27e-2)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (2.06e-1)" "unprognostic (4.04e-3)" "unprognostic (7.89e-3)" "unprognostic (1.07e-1)" "unprognostic (1.49e-2)" "unprognostic (1.60e-1)" "unprognostic (8.77e-3)" "unprognostic (6.87e-3)" "unprognostic (1.54e-1)" "unprognostic (8.73e-2)" "unprognostic (3.65e-2)" "unprognostic (3.95e-1)" "potential prognostic unfavorable (8.74e-4)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (3.08e-1)" SGF29 "CCDC101, FLJ32446, TDRD29" ENSG00000176476 "SAGA complex associated factor 29" Q96ES7 16 28553915-28591790 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Early spermatids: 270.5;Late spermatids: 524.4;Oocytes: 359.2" "Group enriched" "Detected in all" 7 "Oocytes: 359.2;Spermatogenic cell types: 524.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neutrophils: 1627983.6" "Tissue enhanced" "Detected in many" "heart muscle: 1239637.4" "HPA052590, HPA053608" Enhanced Supported Nucleoplasm,Nucleoli Yes No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 154 Nucleoli Nucleoplasm "HPA052590: , HPA053608: " "unprognostic (2.41e-2)" "unprognostic (9.86e-2)" "potential prognostic favorable (3.62e-4)" "unprognostic (9.87e-2)" "unprognostic (4.05e-2)" "unprognostic (1.90e-2)" "potential prognostic favorable (1.02e-4)" "unprognostic (1.10e-1)" "unprognostic (2.47e-1)" "potential prognostic favorable (2.45e-4)" "unprognostic (2.77e-2)" "unprognostic (6.61e-2)" "unprognostic (2.69e-2)" "unprognostic (3.70e-3)" "unprognostic (9.76e-2)" "unprognostic (5.41e-2)" "unprognostic (4.00e-2)" "unprognostic (4.73e-2)" "unprognostic (8.02e-2)" "potential prognostic favorable (3.49e-4)" "unprognostic (3.73e-1)" "unprognostic (4.38e-1)" "unprognostic (9.61e-2)" "unprognostic (3.74e-2)" "unprognostic (7.23e-2)" "unprognostic (8.07e-2)" "unprognostic (4.63e-1)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" SGO1 "NY-BR-85, SGOL1" ENSG00000129810 "Shugoshin 1" Q5FBB7 3 20160593-20186206 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.2;lymphoid tissue: 12.1;testis: 6.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 41.6;Differentiating spermatogonia: 50.6;Early primary spermatocytes: 65.6;Enteric transient amplifying cells: 40.4;Erythrocyte progenitors: 62.9;Esophageal basal cells: 34.9;Extravillous trophoblasts: 57.3;Gastric progenitor cells: 29.5;Late primary spermatocytes: 44.0;Megakaryocyte progenitors: 44.9;Migrating cytotrophoblasts: 35.0;Monocyte progenitors: 66.8;Oocytes: 124.3;Undifferentiated spermatogonia: 37.0" "Cell type enhanced" "Detected in many" "Erythrocytes: 62.9;Mononuclear phagocytes: 66.8;Oocytes: 124.3;Spermatogenic cell types: 65.6;Trophoblast cells: 57.3" "Cell type enhanced" "Detected in some" "leukocyte: 2.4;oligodendrocyte: 2.3;oligodendrocyte precursor cell: 3.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 10.2;memory B-cell: 8.9;naive B-cell: 9.0;plasmacytoid DC: 4.2;T-reg: 2.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 27 "Granulosa cells: 2657.5" "Group enriched" "Detected in some" 90559 "cerebral cortex: 6475425.9;lymphoid tissue: 11636337.2" "HPA035501, HPA069302, HPA069857" Enhanced Approved Nucleoplasm,Kinetochore,Cytosol Yes Yes "Cluster 17: B-cells - Immunoglobulins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 6: Non-specific - Immune response" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 26 Nucleoplasm "Kinetochore, Cytosol" "HPA035501: , HPA069302: , HPA069857: " "unprognostic (3.88e-2)" "unprognostic (5.99e-2)" "unprognostic (2.08e-1)" "unprognostic (1.31e-1)" "unprognostic (2.18e-1)" "unprognostic (3.82e-2)" "unprognostic (4.53e-3)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (3.79e-6)" "potential prognostic unfavorable (1.42e-5)" "unprognostic (3.58e-3)" "unprognostic (3.27e-2)" "unprognostic (7.30e-2)" "unprognostic (7.24e-2)" "unprognostic (3.62e-1)" "potential prognostic unfavorable (6.26e-5)" "unprognostic (1.48e-2)" "unprognostic (2.22e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" "unprognostic (1.90e-2)" "unprognostic (4.82e-2)" "unprognostic (2.27e-2)" SGPP1 ENSG00000126821 "Sphingosine-1-phosphate phosphatase 1" Q9BX95 14 63684216-63728065 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bergmann glia: 53.3;Distal convoluted tubule cells: 186.9;Ependymal cells: 45.4;Loop of henle epithelial cells: 46.3;Microglia: 88.9;Oligodendrocyte progenitor cells: 49.1;Oligodendrocytes: 77.4;Papillary tip epithelial cells: 65.5;Proximal tubule cells: 91.3;Renal collecting duct principal cells: 224.7;Renal connecting tubule cells: 381.6" "Cell type enhanced" "Detected in some" "Ductal cells: 381.6;Glial cells: 88.9;Renal nephron cells: 186.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 7333356.7" "Group enriched" "Detected in some" "lung: 32879789.1;lymphoid tissue: 87682018.9;salivary gland: 45317166.7" "HPA053149, HPA064908" Approved Supported Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 36: Brain & Liver - Signaling" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 102: Non-specific - Mixed function" 7 Nucleoplasm "HPA053149: , HPA064908: " "unprognostic (2.42e-1)" "unprognostic (8.55e-3)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (5.68e-5)" "unprognostic (6.73e-2)" "unprognostic (5.21e-2)" "unprognostic (1.94e-1)" "unprognostic (7.05e-2)" "unprognostic (3.16e-2)" "unprognostic (2.10e-2)" "potential prognostic favorable (6.33e-6)" "unprognostic (2.40e-2)" "unprognostic (5.74e-3)" "unprognostic (2.66e-3)" "unprognostic (3.41e-1)" "unprognostic (7.52e-3)" "unprognostic (6.27e-3)" "unprognostic (2.72e-2)" "unprognostic (6.27e-2)" "unprognostic (1.58e-1)" "unprognostic (9.78e-3)" "unprognostic (1.50e-1)" "potential prognostic unfavorable (2.67e-4)" "unprognostic (2.82e-1)" "unprognostic (1.52e-1)" "unprognostic (1.21e-1)" "unprognostic (1.52e-1)" "unprognostic (5.45e-2)" "unprognostic (1.25e-1)" "unprognostic (1.25e-1)" "unprognostic (2.16e-1)" SGSM2 "KIAA0397, RUTBC1" ENSG00000141258 "Small G protein signaling modulator 2" O43147 17 2337498-2381058 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 266.1;Epididymal principal cells: 139.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 266.1;Reproductive supporting cells: 139.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 7.1" "Lineage enriched" "Detected in many" 6 "granulocytes: 7.1" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Colon - Enteric glia cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 520990.4;Microglia and Neuropil: 1167825.1" "Tissue enriched" "Detected in single" 172 "cerebral cortex: 17231.5" "HPA021641, HPA024553" Approved Approved Nucleoplasm,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 78: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 1 "Nucleoplasm, Cytosol" "HPA021641: , HPA024553: " "unprognostic (1.89e-1)" "unprognostic (5.05e-2)" "unprognostic (2.65e-1)" "unprognostic (1.40e-1)" "unprognostic (4.48e-2)" "unprognostic (3.33e-1)" "unprognostic (1.54e-1)" "unprognostic (5.42e-3)" "unprognostic (1.64e-3)" "unprognostic (7.08e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "potential prognostic favorable (9.33e-4)" "unprognostic (4.45e-1)" "unprognostic (1.65e-2)" "unprognostic (6.98e-3)" "unprognostic (4.08e-1)" "unprognostic (9.83e-2)" "unprognostic (9.58e-3)" "unprognostic (1.65e-1)" "unprognostic (1.55e-3)" "potential prognostic favorable (3.01e-6)" "unprognostic (1.30e-2)" "unprognostic (2.29e-2)" "unprognostic (4.55e-1)" "unprognostic (5.80e-2)" "unprognostic (5.61e-2)" "unprognostic (4.79e-2)" "unprognostic (1.82e-1)" "unprognostic (1.16e-1)" "unprognostic (3.71e-1)" SGTB "FLJ39002, Sgt2" ENSG00000197860 "Small glutamine rich tetratricopeptide repeat co-chaperone beta" Q96EQ0 5 65665928-65723035 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 30.0" "Cell type enhanced" "Detected in many" "monocytes: 55.9;Müller glia: 77.8;Neutrophil progenitors: 63.1;Neutrophils: 113.8;Retinal horizontal cells: 84.1;T-cells: 49.3" "Cell type enhanced" "Detected in all" "Glial cells: 77.8;Neuronal cells: 84.1;Neutrophils: 113.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "granulocytes: 10.1;monocytes: 6.7;T-cells: 13.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 10862053.9;Collecting ducts: 3262093.8;Microglia and Neuropil: 9087938.8;Neurons: 11053450.5" "Tissue enriched" "Detected in many" "cerebral cortex: 26144430.9" "HPA044689, HPA063674" Enhanced Approved "Nucleoplasm,Nuclear speckles,Microtubules,Primary cilium,Basal body" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 9: T-cells - Adaptive immunity: Regulation" 104 "Nucleoplasm, Primary cilium" "Nuclear speckles, Microtubules, Basal body" "HPA044689: , HPA063674: " "unprognostic (2.38e-1)" "unprognostic (1.70e-1)" "unprognostic (9.88e-2)" "unprognostic (8.01e-3)" "unprognostic (9.85e-2)" "unprognostic (3.49e-2)" "unprognostic (3.81e-1)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (2.73e-1)" "unprognostic (9.66e-3)" "potential prognostic favorable (9.35e-5)" "unprognostic (6.38e-2)" "unprognostic (2.54e-3)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (1.03e-1)" "unprognostic (9.91e-2)" "unprognostic (5.98e-3)" "unprognostic (1.41e-1)" "unprognostic (9.65e-2)" "unprognostic (1.86e-1)" "unprognostic (2.73e-3)" "unprognostic (1.28e-3)" "unprognostic (9.77e-3)" "unprognostic (3.75e-2)" "unprognostic (1.69e-1)" "unprognostic (1.16e-2)" "unprognostic (2.54e-1)" "unprognostic (5.54e-2)" "unprognostic (3.70e-2)" "unprognostic (3.44e-2)" "unprognostic (2.30e-1)" SH2B1 "FLJ30542, SH2B" ENSG00000178188 "SH2B adaptor protein 1" Q9NRF2 16 28846600-28874212 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 118.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 9342929.8" "Low tissue specificity" "Detected in many" "HPA060663, HPA076175" Enhanced Approved "Nucleoplasm,Centriolar satellite,Cytosol" NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 54: Non-specific - Transcription" "Cluster 89: Adipocytes - Lipid metabolism" 16 Nucleoplasm "Centriolar satellite, Cytosol" "HPA060663: , HPA076175: " "unprognostic (1.45e-2)" "unprognostic (2.65e-1)" "unprognostic (1.90e-1)" "unprognostic (2.64e-1)" "unprognostic (9.02e-2)" "unprognostic (8.39e-2)" "unprognostic (1.27e-1)" "unprognostic (2.14e-2)" "unprognostic (1.21e-2)" "unprognostic (3.34e-1)" "unprognostic (5.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.00e-3)" "unprognostic (1.01e-2)" "unprognostic (2.87e-1)" "unprognostic (2.91e-3)" "unprognostic (2.56e-1)" "unprognostic (2.62e-2)" "unprognostic (2.07e-2)" "unprognostic (1.82e-1)" "unprognostic (1.21e-2)" "unprognostic (5.70e-3)" "unprognostic (1.52e-2)" "unprognostic (6.97e-3)" "unprognostic (3.11e-2)" "unprognostic (4.32e-1)" "unprognostic (5.01e-2)" "unprognostic (1.67e-1)" "unprognostic (3.20e-1)" "unprognostic (3.43e-2)" "unprognostic (3.67e-1)" SH2D3A NSP1 ENSG00000125731 "SH2 domain containing 3A" Q9BRG2 19 6752160-6767463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 31.2" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 155.7;Extravillous trophoblasts: 85.6;Urothelial cells: 114.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 155.7;Barrier epithelial cells: 114.0" "Cell type enriched" "Detected in some" 6 "leukocyte: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose visceral - T-cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Collecting ducts: 184638.0;Fallopian tube cells: 207320.9;Pancreas epithelial cells: 524948.8" "Tissue enriched" "Detected in single" 3761 "heart muscle: 376074.2" "HPA035722, HPA064382" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge" Yes NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 54 Microtubules "Nucleoplasm, Cytokinetic bridge" "HPA035722: , HPA064382: " "unprognostic (1.52e-1)" "unprognostic (2.45e-2)" "unprognostic (1.10e-1)" "unprognostic (1.30e-2)" "unprognostic (3.37e-2)" "unprognostic (1.62e-1)" "unprognostic (5.02e-2)" "unprognostic (8.77e-3)" "potential prognostic favorable (3.76e-5)" "unprognostic (1.87e-2)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (3.22e-4)" "unprognostic (1.87e-1)" "unprognostic (1.67e-1)" "unprognostic (7.41e-2)" "unprognostic (2.44e-2)" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (6.20e-2)" "unprognostic (2.02e-3)" "unprognostic (5.25e-2)" "unprognostic (1.56e-2)" "unprognostic (2.69e-1)" "unprognostic (2.96e-2)" "unprognostic (2.59e-1)" "unprognostic (5.15e-3)" "unprognostic (3.76e-2)" SH2D7 LOC646892 ENSG00000183476 "SH2 domain containing 7" A6NKC9 15 78077808-78104370 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 9 "intestine: 2.2;testis: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 242.8;Late primary spermatocytes: 393.2;Late spermatids: 224.9;Tuft cells: 1003.0" "Group enriched" "Detected in some" 208 "Secretory gland support: 1003.0;Spermatogenic cell types: 393.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "skin cancer: 1.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051320, HPA058382, HPA076728" Enhanced Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 95: Tuft cells - Chemosensory signaling" Nucleoli "Nucleoplasm, Cytosol" "HPA051320: , HPA058382: , HPA076728: " "unprognostic (3.27e-1)" SH3BGRL MGC117402 ENSG00000131171 "SH3 domain binding glutamate rich protein like" O75368 X 81202102-81298547 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 615.2;Platelets: 793.2;Smooth muscle cells: 620.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA030507, HPA051248" Approved Supported Cytosol NA NA 12000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 27: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 62: Smooth muscle cells - Muscle contraction" 5 Cytosol "HPA030507: , HPA051248: " "potential prognostic favorable (3.50e-5)" "unprognostic (2.55e-2)" "unprognostic (2.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.86e-1)" "unprognostic (1.48e-2)" "unprognostic (2.96e-1)" "unprognostic (2.08e-1)" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (7.91e-8)" "unprognostic (2.86e-1)" "unprognostic (9.60e-2)" "unprognostic (3.26e-2)" "unprognostic (7.15e-2)" "unprognostic (1.81e-2)" "unprognostic (2.15e-1)" "unprognostic (3.77e-2)" "unprognostic (7.81e-3)" "unprognostic (1.36e-1)" "unprognostic (2.79e-3)" "unprognostic (2.44e-1)" "unprognostic (2.03e-1)" "unprognostic (7.94e-2)" "unprognostic (2.82e-1)" "unprognostic (1.24e-1)" "unprognostic (4.40e-2)" "unprognostic (1.70e-3)" "unprognostic (6.93e-2)" "unprognostic (2.75e-1)" "unprognostic (6.94e-2)" SH3BGRL3 ENSG00000142669 "SH3 domain binding glutamate rich protein like 3" Q9H299 1 26280086-26281522 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 1845.5;Epididymal principal cells: 2052.6;Esophageal apical cells: 5483.2;Esophageal suprabasal cells: 3161.7;Hofbauer cells: 2083.5;Megakaryocytes: 6058.0;monocytes: 2333.5;Platelets: 11941.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 5483.2;Megakaryocytes: 6058.0;Platelets: 11941.1" "Cell type enhanced" "Detected in all" "leukocyte: 215.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA030848, HPA076219" Enhanced Approved "Nuclear bodies" NA NA 65000000 "Cluster 29: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 47: Platelets - Hemostasis" 4 "Nuclear bodies" "HPA030848: , HPA076219: " "unprognostic (7.95e-2)" "unprognostic (3.82e-2)" "unprognostic (3.16e-2)" "unprognostic (9.77e-2)" "unprognostic (6.98e-2)" "unprognostic (3.40e-3)" "unprognostic (1.68e-2)" "unprognostic (1.45e-2)" "unprognostic (1.49e-1)" "unprognostic (6.30e-2)" "potential prognostic unfavorable (1.57e-7)" "unprognostic (3.95e-3)" "unprognostic (1.97e-1)" "unprognostic (7.89e-3)" "unprognostic (4.21e-2)" "unprognostic (1.15e-2)" "unprognostic (2.41e-3)" "unprognostic (4.00e-1)" "unprognostic (5.47e-2)" "unprognostic (2.53e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-2)" "unprognostic (6.91e-2)" "unprognostic (3.05e-1)" "potential prognostic unfavorable (4.10e-4)" "unprognostic (4.60e-2)" "unprognostic (1.57e-1)" "unprognostic (1.72e-1)" "unprognostic (3.20e-2)" "unprognostic (1.95e-1)" "unprognostic (1.76e-1)" SH3BP1 ARHGAP43 ENSG00000100092 "SH3 domain binding protein 1" Q9Y3L3 22 37634654-37656117 "Metabolic proteins, Predicted intracellular proteins" Phagocytosis "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 38.9" "Cell type enriched" "Detected in some" 5 "Microglia: 35.2" "Cell type enriched" "Detected in many" 5 "Glial cells: 35.2" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 45.0;leukocyte: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Macrophages, Skin - Keratinocyte (other), Spleen - T-cells, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "B-cells: 8273871.9;Macrophages: 8039411.6;T-cells: 16848454.2" "Group enriched" "Detected in many" "bone marrow: 8168168.4;lung: 4335955.3;lymphoid tissue: 10207803.8" HPA000757 Supported Supported Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 102: Non-specific - Mixed function" 14 Cytosol "HPA000757: " "unprognostic (9.10e-2)" "unprognostic (4.08e-3)" "unprognostic (7.68e-2)" "unprognostic (9.70e-2)" "unprognostic (1.99e-1)" "unprognostic (8.43e-2)" "unprognostic (1.53e-1)" "unprognostic (1.10e-1)" "unprognostic (1.86e-1)" "unprognostic (1.98e-1)" "unprognostic (5.98e-3)" "unprognostic (1.16e-1)" "unprognostic (8.90e-3)" "unprognostic (2.65e-3)" "unprognostic (7.56e-2)" "unprognostic (3.05e-1)" "unprognostic (8.83e-2)" "unprognostic (2.90e-2)" "unprognostic (1.26e-2)" "unprognostic (2.15e-1)" "unprognostic (1.16e-1)" "unprognostic (6.64e-2)" "unprognostic (8.06e-3)" "unprognostic (1.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.57e-1)" "unprognostic (4.07e-1)" "potential prognostic favorable (9.71e-5)" "unprognostic (2.71e-1)" "unprognostic (2.25e-1)" "unprognostic (1.67e-1)" SH3BP5 Sab ENSG00000131370 "SH3 domain binding protein 5" O60239 3 15254353-15341368 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 806.2;Early spermatids: 302.6;Extravillous trophoblasts: 618.5;monocytes: 351.7;Neutrophils: 795.1;Syncytiotrophoblasts: 298.8" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 806.2;Neutrophils: 795.1;Trophoblast cells: 618.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Macrophages: 828563.6;Neurons: 539193.6;Proximal tubules: 1494476.3" "Not detected" "Not detected" "HPA036445, HPA057988" Uncertain Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 12 "Nucleoplasm, Nuclear bodies" "HPA036445: , HPA057988: " "unprognostic (1.98e-2)" "potential prognostic favorable (2.74e-4)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-2)" "unprognostic (1.86e-1)" "unprognostic (1.52e-1)" "unprognostic (5.36e-3)" "unprognostic (1.61e-1)" "potential prognostic favorable (4.40e-7)" "unprognostic (1.20e-3)" "unprognostic (1.55e-2)" "unprognostic (9.65e-3)" "unprognostic (5.51e-3)" "potential prognostic favorable (4.19e-4)" "unprognostic (3.01e-1)" "unprognostic (4.77e-1)" "unprognostic (1.88e-1)" "unprognostic (4.29e-2)" "unprognostic (1.21e-3)" "unprognostic (3.18e-1)" "unprognostic (2.20e-1)" "unprognostic (2.80e-1)" "unprognostic (1.86e-1)" "unprognostic (2.43e-3)" "unprognostic (1.25e-1)" "unprognostic (1.26e-1)" "unprognostic (1.10e-1)" "unprognostic (6.61e-2)" "unprognostic (2.90e-2)" SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 32.8" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 39.0;Enterocytes: 36.2;Esophageal apical cells: 33.4;Late spermatids: 90.0" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 90.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Stomach - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1608 "Distal tubules: 125473.0;Large ducts: 196073.9" "Not detected" "Not detected" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane,Basal body" NA NA "Cluster 58: Skin - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 1 "Plasma membrane" "Nucleoplasm, Basal body" "HPA042212: , HPA042456: , HPA066168: " "unprognostic (1.23e-1)" "unprognostic (1.43e-3)" "unprognostic (2.69e-2)" "unprognostic (1.20e-1)" "unprognostic (2.51e-1)" "unprognostic (2.28e-3)" "unprognostic (2.88e-1)" "unprognostic (2.91e-2)" "unprognostic (1.27e-3)" "unprognostic (1.25e-2)" "unprognostic (5.12e-2)" "unprognostic (6.30e-2)" "unprognostic (2.25e-2)" "unprognostic (1.15e-1)" "unprognostic (1.59e-2)" "unprognostic (2.88e-1)" "unprognostic (1.46e-1)" "unprognostic (3.95e-2)" "unprognostic (3.12e-2)" "unprognostic (1.41e-2)" "unprognostic (2.52e-2)" "unprognostic (1.67e-1)" "unprognostic (1.02e-2)" "unprognostic (8.03e-2)" "unprognostic (3.62e-2)" "unprognostic (8.19e-2)" "unprognostic (2.68e-1)" "unprognostic (1.21e-1)" "unprognostic (2.88e-1)" SH3GL2 "CNSA2, EEN-B1, SH3D2A, SH3P4" ENSG00000107295 "SH3 domain containing GRB2 like 2, endophilin A1" Q99962 9 17579066-17797124 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 227.8;retina: 69.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 549.9;Brain inhibitory neurons: 235.6;Cone photoreceptor cells: 443.0;Corticotrophs: 316.8;Gonadotrophs: 157.7;Lactotrophs: 254.6;Pancreatic islet cells: 199.8;Proximal tubule cells: 160.3;Retinal amacrine cells: 243.1;Retinal bipolar cells: 470.0;Retinal ganglion cells: 170.0;Rod photoreceptor cells: 171.5;Somatotrophs: 241.1;Thyrotrophs: 263.9" "Cell type enhanced" "Detected in many" "Neuronal cells: 549.9;Pancreatic islet cells: 199.8;Pituitary endocrine cells: 316.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 13.4;Kidney Chromophobe (TCGA): 8.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 6.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "cervical cancer: 10.1" "Adipose visceral - Mesothelial cells, Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Alveolar cells type 1, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 79081650.4;Microglia and Neuropil: 98686866.8;Neurons: 58440304.0" "Tissue enriched" "Detected in many" "cerebral cortex: 278777406.6" "CAB010056, HPA026685, HPA063573" Enhanced Supported Approved "Microtubules,Cytokinetic bridge,Mitotic spindle" Yes No "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 48 Microtubules "Cytokinetic bridge, Mitotic spindle" "CAB010056: , HPA026685: , HPA063573: " "unprognostic (8.86e-2)" "unprognostic (4.62e-2)" "unprognostic (2.35e-2)" "potential prognostic favorable (5.52e-5)" "unprognostic (2.67e-1)" "unprognostic (1.67e-2)" "unprognostic (3.23e-1)" "potential prognostic favorable (6.55e-6)" "unprognostic (9.44e-3)" "unprognostic (5.79e-2)" "unprognostic (7.03e-2)" "unprognostic (6.79e-2)" "unprognostic (8.39e-2)" "unprognostic (1.99e-2)" SH3GLB1 "Bif-1, CGI-61, KIAA0491, PPP1R70" ENSG00000097033 "SH3 domain containing GRB2 like, endophilin B1" Q9Y371 1 86704570-86748184 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 578.0;Esophageal apical cells: 1111.7;Late primary spermatocytes: 954.3;Neutrophils: 1166.1" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1111.7;Neutrophils: 1166.1;Spermatogenic cell types: 954.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 302.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004650, HPA015608, HPA019900" Enhanced Supported Cytosol NA NA 12000 "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 129 Cytosol "CAB004650: , HPA015608: , HPA019900: " "unprognostic (4.31e-2)" "unprognostic (3.04e-1)" "unprognostic (2.99e-1)" "unprognostic (1.70e-2)" "unprognostic (2.90e-2)" "unprognostic (1.87e-1)" "unprognostic (2.45e-1)" "unprognostic (1.05e-2)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (3.47e-4)" "validated prognostic favorable (1.54e-7)" "validated prognostic favorable (3.70e-5)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (1.34e-6)" "unprognostic (5.10e-2)" "unprognostic (2.80e-2)" "unprognostic (5.92e-3)" "unprognostic (9.65e-2)" "unprognostic (1.71e-2)" "unprognostic (6.26e-2)" "unprognostic (9.85e-2)" "unprognostic (4.78e-3)" "unprognostic (1.40e-1)" "unprognostic (3.12e-1)" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (2.46e-1)" "unprognostic (8.39e-2)" "unprognostic (2.47e-1)" "unprognostic (8.82e-2)" "unprognostic (1.08e-1)" SH3RF1 "KIAA1494, POSH, RNF142, SH3MD2" ENSG00000154447 "SH3 domain containing ring finger 1" Q7Z6J0 4 169094259-169270956 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 607.0;Ocular epithelial cells: 684.8;Podocytes: 847.1;Renal connecting tubule cells: 654.9;Salivary acinar cells: 859.0;Urothelial cells: 623.1" "Cell type enhanced" "Detected in many" "Acinar cells: 859.0;Renal nephron cells: 847.1" "Cell type enhanced" "Detected in all" "pericyte: 748.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "intermediate monocyte: 4.2;myeloid DC: 2.5;non-classical monocyte: 6.8" "Group enriched" "Detected in many" 15 "dendritic cells: 2.5;monocytes: 6.8" "Low cancer specificity" "Detected in all" "Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 469840.0" "Group enriched" "Detected in many" "intestine: 529168.8;Stomach: 1995434.1" HPA074783 Approved Supported "Vesicles,Intermediate filaments" No No "Cluster 40: Monocytes - Innate immune response" "Cluster 60: Stomach - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 20 Vesicles "Intermediate filaments" "HPA074783: " "unprognostic (1.38e-1)" "unprognostic (6.51e-2)" "unprognostic (4.81e-3)" "unprognostic (9.59e-2)" "unprognostic (2.62e-2)" "unprognostic (2.62e-1)" "unprognostic (1.16e-1)" "unprognostic (1.37e-1)" "unprognostic (8.77e-3)" "unprognostic (3.30e-1)" "validated prognostic favorable (8.55e-8)" "validated prognostic favorable (2.03e-5)" "unprognostic (4.70e-2)" "unprognostic (8.69e-2)" "unprognostic (2.75e-3)" "unprognostic (4.07e-1)" "unprognostic (2.35e-2)" "unprognostic (8.39e-3)" "unprognostic (1.07e-1)" "unprognostic (4.77e-2)" "unprognostic (7.64e-2)" "unprognostic (1.25e-2)" "unprognostic (9.88e-2)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (2.61e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.59e-1)" "unprognostic (1.91e-2)" "unprognostic (2.28e-1)" SH3RF3 "FLJ00204, POSH2, SH3MD4" ENSG00000172985 "SH3 domain containing ring finger 3" Q8TEJ3 2 109129205-109504634 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 200.0;Fibro-adipogenic progenitors: 198.7;Microglia: 627.5;Retinal horizontal cells: 166.3;Vascular endothelial cells: 221.4;Vascular smooth muscle cells: 287.4" "Cell type enhanced" "Detected in many" "Glial cells: 627.5;Mural cells: 287.4" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 834.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 90 "Fallopian tube cells: 9037.3" "Tissue enriched" "Detected in single" 136 "cerebral cortex: 13649.2" "HPA044822, HPA048444" Approved Supported Nucleoplasm Yes No "Cluster 74: Non-specific - Signal transduction" "Cluster 51: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 8 Nucleoplasm "HPA044822: , HPA048444: " "unprognostic (7.30e-2)" "unprognostic (3.30e-1)" "unprognostic (6.16e-2)" "unprognostic (2.43e-3)" "unprognostic (1.38e-1)" "unprognostic (1.50e-2)" "unprognostic (2.86e-1)" "unprognostic (6.27e-2)" "unprognostic (3.48e-1)" "potential prognostic favorable (9.85e-4)" "unprognostic (5.17e-2)" "unprognostic (6.52e-3)" "unprognostic (1.62e-1)" "unprognostic (2.66e-3)" "unprognostic (1.62e-1)" "unprognostic (6.54e-2)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "validated prognostic unfavorable (2.41e-4)" "validated prognostic unfavorable (5.33e-4)" "unprognostic (5.94e-2)" "unprognostic (8.78e-2)" "unprognostic (3.39e-1)" "unprognostic (2.25e-1)" "unprognostic (2.16e-3)" "unprognostic (2.25e-2)" "unprognostic (6.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-1)" SH3TC2 "CMT4C, KIAA1985" ENSG00000169247 "SH3 domain and tetratricopeptide repeats 2" Q8TF17 5 148923639-149063163 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.5;retina: 3.6;testis: 1.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 53.4;Esophageal apical cells: 70.4;Oligodendrocytes: 286.3;Platelets: 91.7;Rod photoreceptor cells: 192.9;Sertoli cells: 156.6;Syncytiotrophoblasts: 75.9;Tuft cells: 46.1" "Cell type enhanced" "Detected in many" "Glial cells: 286.3;Neuronal cells: 192.9;Reproductive supporting cells: 156.6" "Group enriched" "Detected in many" 8 "committed oligodendrocyte precursor: 104.4;oligodendrocyte: 386.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.4;skin cancer: 4.9" "Breast - Breast myoepithelial cells, Skin - Sebaceous gland cells, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6309 "Astrocytes and Neuropil: 517395.6;Glomeruli: 744320.0" "Not detected" "Not detected" "HPA037683, HPA037684" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 79: Photoreceptor cells - Phototransduction" "Nucleoplasm, Cytosol" "HPA037683: , HPA037684: " "unprognostic (2.33e-1)" "unprognostic (5.99e-2)" "unprognostic (6.00e-2)" "unprognostic (5.83e-2)" "unprognostic (5.49e-2)" SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.8" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 1257.3;Ependymal cells: 597.4;Proximal tubule cells: 563.9;Renal collecting duct intercalated cells: 600.1;Renal connecting tubule cells: 517.9;Respiratory ciliated cells: 647.7;Retinal horizontal cells: 1059.8;Retinal pigment epithelial cells: 541.4;Salivary acinar cells: 523.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 1257.3;Neuronal cells: 1059.8" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 1205.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Eccrine sweat gland cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 11705245.1" "Group enriched" "Detected in many" "cerebral cortex: 6984628.3;heart muscle: 13015120.3;lung: 8765420.2" "HPA008174, HPA017220" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" 7 "Nuclear speckles, Vesicles" "Nucleoplasm, Plasma membrane" "HPA008174: , HPA017220: " "unprognostic (1.11e-1)" "unprognostic (2.54e-1)" "unprognostic (4.04e-1)" "potential prognostic unfavorable (4.85e-5)" "unprognostic (1.09e-1)" "unprognostic (8.24e-2)" "unprognostic (2.92e-1)" "unprognostic (5.01e-2)" "unprognostic (1.29e-3)" "unprognostic (1.91e-1)" "potential prognostic favorable (1.10e-7)" "unprognostic (7.48e-2)" "unprognostic (9.46e-2)" "unprognostic (2.46e-1)" "potential prognostic favorable (2.44e-4)" "unprognostic (3.12e-1)" "unprognostic (2.47e-1)" "unprognostic (2.79e-3)" "unprognostic (5.98e-1)" "unprognostic (2.00e-1)" "unprognostic (1.30e-2)" "unprognostic (8.94e-3)" "unprognostic (4.51e-2)" "unprognostic (3.14e-1)" "unprognostic (2.89e-2)" "unprognostic (5.55e-2)" "unprognostic (6.22e-2)" "unprognostic (1.97e-3)" "unprognostic (3.69e-2)" "unprognostic (1.58e-1)" SHCBP1 "FLJ22009, PAL" ENSG00000171241 "SHC binding and spindle associated 1" Q8NEM2 16 46578591-46621379 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 16.4;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 51.2;Differentiating spermatogonia: 30.4;Early primary spermatocytes: 42.9;Erythrocyte progenitors: 93.3;Extravillous trophoblasts: 43.3;Megakaryocyte progenitors: 54.1;Monocyte progenitors: 127.1;Neutrophil progenitors: 95.1;Plasma cells: 49.2;Renal connecting tubule cells: 32.9" "Cell type enhanced" "Detected in many" "Erythrocytes: 93.3;Mononuclear phagocytes: 127.1;Neutrophils: 95.1" "Cell type enhanced" "Detected in many" "Bergmann glia: 55.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Ascending Loop of Henle cells, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" 2025 "Granulosa cells: 236033.2;Oocytes: 169023.7" "Not detected" "Not detected" HPA048876 Uncertain Approved "Nuclear bodies,Microtubules,Midbody,Mitotic spindle" Yes Yes "Cluster 23: B-cells - Immunoglobulins" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 27: Non-specific - Cell proliferation" 27 "Nuclear bodies" "Microtubules, Midbody, Mitotic spindle" "HPA048876: " "unprognostic (1.16e-2)" "potential prognostic unfavorable (3.59e-4)" "unprognostic (3.38e-1)" "unprognostic (1.18e-1)" "unprognostic (1.36e-1)" "unprognostic (1.04e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-1)" "unprognostic (6.29e-2)" "unprognostic (6.22e-3)" "validated prognostic unfavorable (1.94e-6)" "validated prognostic unfavorable (2.85e-6)" "potential prognostic unfavorable (2.94e-11)" "validated prognostic unfavorable (1.84e-4)" "validated prognostic unfavorable (5.01e-8)" "potential prognostic unfavorable (9.92e-7)" "unprognostic (1.34e-3)" "unprognostic (2.39e-1)" "unprognostic (1.25e-2)" "unprognostic (3.95e-1)" "unprognostic (3.90e-2)" "validated prognostic unfavorable (1.43e-7)" "validated prognostic unfavorable (5.21e-5)" "unprognostic (2.52e-3)" "unprognostic (8.34e-2)" "unprognostic (3.64e-2)" "unprognostic (3.24e-1)" "unprognostic (2.60e-1)" "unprognostic (3.26e-2)" SHD ENSG00000105251 "Src homology 2 domain containing transforming protein D" Q96IW2 19 4279266-4290722 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 12.7;heart muscle: 21.3" "Cell type enriched" "Detected in some" 7 "Oocytes: 925.6" "Cell type enriched" "Detected in many" 7 "Oocytes: 925.6" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 16.1;committed oligodendrocyte precursor: 27.8;oligodendrocyte precursor cell: 19.3" "Cancer enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 27.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 179 "plasmacytoid DC: 17.8" "Lineage enriched" "Detected in single" 179 "dendritic cells: 17.8" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 113.3" "Colon - Colon enterocytes, Liver - Hepatocytes, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 45 "cerebral cortex: 4491.6" HPA017955 Uncertain Uncertain "Centriolar satellite,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 35: Non-specific - Mixed function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 41: Oocytes - Oogenesis" 4 "Centriolar satellite, Cytosol" "HPA017955: " "unprognostic (1.14e-1)" "potential prognostic favorable (8.58e-4)" "unprognostic (3.65e-3)" "unprognostic (4.97e-2)" "unprognostic (2.34e-1)" "unprognostic (1.41e-2)" SHFL "C19orf66, FLJ11286, IRAV, RyDEN, SFL" ENSG00000130813 "Shiftless antiviral inhibitor of ribosomal frameshifting" Q9NUL5 19 10086122-10093252 "Predicted intracellular proteins" "Antiviral defense" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 100.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 101.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 6270098.4" "Tissue enhanced" "Detected in many" "liver: 6278570.6" HPA042001 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 28 Nucleoplasm Cytosol "HPA042001: " "potential prognostic favorable (1.98e-4)" "unprognostic (1.82e-3)" "unprognostic (1.59e-1)" "unprognostic (2.34e-1)" "unprognostic (1.47e-1)" "unprognostic (3.04e-2)" "potential prognostic unfavorable (9.69e-5)" "unprognostic (2.68e-1)" "unprognostic (3.43e-2)" "unprognostic (8.02e-2)" "unprognostic (2.85e-1)" "unprognostic (8.13e-3)" "unprognostic (1.50e-1)" "unprognostic (1.71e-1)" "unprognostic (4.18e-1)" "unprognostic (3.11e-1)" "unprognostic (3.05e-1)" "unprognostic (1.26e-1)" "unprognostic (2.23e-1)" "unprognostic (5.55e-3)" "unprognostic (1.75e-2)" "unprognostic (1.25e-1)" "unprognostic (1.78e-1)" "unprognostic (2.36e-2)" "unprognostic (8.05e-2)" "unprognostic (1.27e-1)" "unprognostic (1.69e-1)" "unprognostic (1.85e-2)" "unprognostic (3.66e-2)" SHISAL1 KIAA1644 ENSG00000138944 "Shisa like 1" Q3SXP7 22 44243665-44312951 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.1;endometrium 1: 29.1;smooth muscle: 27.4" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 11.0;Brain inhibitory neurons: 11.6;Decidual stromal cells: 18.1;Endometrial stromal cells: 6.6;Lactotrophs: 21.4;Oocytes: 9.2;Other brain neurons: 19.1;Pancreatic islet cells: 5.2;Retinal bipolar cells: 10.9;Smooth muscle cells: 19.5" "Cell type enhanced" "Detected in some" "Neuronal cells: 19.1;Oocytes: 9.2;Pituitary endocrine cells: 21.4;Smooth muscle cells: 19.5;Stromal cells: 18.1" "Cell type enhanced" "Detected in many" "mammillary body: 71.5;thalamic excitatory: 60.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 17.4" "Adipose subcutaneous - Smooth muscle cells, Pituitary gland - Lactotropes, Stomach - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 16 "cerebral cortex: 1633.4" HPA051178 Uncertain Approved Vesicles,Cytosol No No "Cluster 65: Brain - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 43 "Vesicles, Cytosol" "HPA051178: " "unprognostic (1.93e-2)" "unprognostic (5.46e-3)" "unprognostic (5.73e-3)" "unprognostic (1.69e-1)" "unprognostic (1.35e-1)" "unprognostic (1.45e-3)" "unprognostic (1.16e-1)" "unprognostic (4.24e-2)" "unprognostic (8.02e-2)" "unprognostic (1.90e-1)" "unprognostic (1.39e-2)" "unprognostic (1.69e-1)" "unprognostic (4.92e-2)" "unprognostic (9.49e-2)" "unprognostic (3.42e-2)" "unprognostic (2.80e-2)" "unprognostic (1.45e-2)" "unprognostic (4.62e-2)" SHKBP1 "PP203, Sb1" ENSG00000160410 "SH3KBP1 binding protein 1" Q8TBC3 19 40576853-40591399 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 124.1" "Cell type enriched" "Detected in many" 4 "Neutrophils: 511.4" "Cell type enriched" "Detected in all" 4 "Neutrophils: 511.4" "Cell type enhanced" "Detected in many" "leukocyte: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 838643.4;Neutrophils: 773711.1" "Tissue enriched" "Detected in some" "lymphoid tissue: 1836989.3" HPA041887 Uncertain Approved "Cell Junctions" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 35: RS4;11 - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 40 "Cell Junctions" "HPA041887: " "unprognostic (5.61e-2)" "unprognostic (1.35e-1)" "unprognostic (8.62e-2)" "unprognostic (8.72e-3)" "unprognostic (2.54e-1)" "unprognostic (2.20e-1)" "unprognostic (2.27e-1)" "unprognostic (3.11e-1)" "unprognostic (2.03e-1)" "unprognostic (1.26e-1)" "unprognostic (1.53e-3)" "unprognostic (1.84e-2)" "unprognostic (5.13e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (1.15e-2)" "unprognostic (1.47e-2)" "unprognostic (1.22e-1)" "unprognostic (2.17e-1)" "unprognostic (5.53e-2)" "unprognostic (2.79e-1)" "unprognostic (5.28e-2)" "unprognostic (1.88e-1)" "potential prognostic unfavorable (4.18e-4)" "unprognostic (1.63e-1)" "unprognostic (5.02e-1)" "unprognostic (4.52e-2)" "unprognostic (2.44e-2)" "unprognostic (1.70e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "unprognostic (6.47e-2)" SHLD3 "AC008560.1, CTC-534A2.2, FLJ26957, RINN1" ENSG00000253251 "Shieldin complex subunit 3" Q6ZNX1 5 65625027-65630928 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA068764 Approved Approved Nucleoplasm,Nucleoli No No "Cluster 19: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 1 "Nucleoplasm, Nucleoli" "HPA068764: " "unprognostic (3.99e-2)" "unprognostic (1.54e-1)" "unprognostic (1.37e-1)" "unprognostic (3.32e-1)" "unprognostic (2.46e-2)" "unprognostic (2.80e-1)" "unprognostic (2.03e-2)" "unprognostic (7.64e-2)" "unprognostic (1.40e-1)" "unprognostic (2.43e-1)" "unprognostic (3.89e-1)" "unprognostic (8.53e-2)" "unprognostic (2.24e-3)" "unprognostic (2.33e-1)" "unprognostic (9.38e-2)" "unprognostic (3.66e-2)" "unprognostic (1.14e-1)" "unprognostic (1.50e-1)" "unprognostic (1.55e-1)" "potential prognostic favorable (2.73e-4)" "potential prognostic unfavorable (3.08e-4)" "potential prognostic unfavorable (1.45e-4)" "unprognostic (1.59e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" "unprognostic (2.54e-1)" "unprognostic (1.19e-1)" "unprognostic (3.92e-2)" "unprognostic (1.88e-1)" SHROOM2 APXL ENSG00000146950 "Shroom family member 2" Q13796 X 9786429-9949443 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 19.3" "Cell type enhanced" "Detected in many" "Peritubular myoid cells: 149.0;Renal collecting duct intercalated cells: 160.1;Rod photoreceptor cells: 107.2;Tuft cells: 138.3" "Cell type enhanced" "Detected in many" "Ductal cells: 160.1;Secretory gland support: 138.3;Stromal cells: 149.0" "Cell type enhanced" "Detected in all" "endothelial cell: 183.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 17.1" "Prostate - Prostate glandular cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 3063685.6" "Tissue enriched" "Detected in some" "cerebral cortex: 4936197.2" "HPA051646, HPA061435" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" No No "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 53: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 104: Brain endothelial cells - Blood brain barrier" "Plasma membrane, Cell Junctions" Cytosol "HPA051646: , HPA061435: " "unprognostic (8.83e-2)" "unprognostic (1.35e-2)" "unprognostic (8.62e-2)" "unprognostic (2.46e-2)" "unprognostic (6.10e-2)" "unprognostic (1.11e-1)" "unprognostic (2.42e-2)" "unprognostic (5.17e-2)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "potential prognostic favorable (4.71e-7)" "unprognostic (3.83e-3)" "unprognostic (1.97e-1)" "unprognostic (3.19e-2)" "unprognostic (2.91e-3)" "unprognostic (3.06e-1)" "unprognostic (2.26e-1)" "unprognostic (7.88e-2)" "unprognostic (1.27e-3)" "unprognostic (3.35e-1)" "unprognostic (8.77e-2)" "unprognostic (2.39e-2)" "unprognostic (1.30e-2)" "unprognostic (1.92e-1)" "unprognostic (4.12e-3)" "unprognostic (6.76e-3)" "unprognostic (3.39e-1)" "unprognostic (1.12e-1)" "unprognostic (3.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.75e-2)" SHTN1 "KIAA1598, shootin-1, shootin1" ENSG00000187164 "Shootin 1" A0MZ66 10 116881477-117126586 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 53.0" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 523.9;Corticotrophs: 439.8;Gonadotrophs: 591.2;Lactotrophs: 499.3;Microglia: 708.4;Oligodendrocytes: 1442.2;Somatotrophs: 476.9" "Cell type enhanced" "Detected in all" "Glial cells: 1442.2;Pituitary endocrine cells: 591.2" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1894.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 30 "classical monocyte: 19.8;intermediate monocyte: 12.9;myeloid DC: 19.3;non-classical monocyte: 6.6;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 42 "dendritic cells: 19.3;monocytes: 19.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Spleen - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "cerebral cortex: 62298432.7" "HPA037942, HPA037943, HPA075224" Enhanced Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Basal body,Cytosol" NA NA 5600 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 7: Liver cancer - Metabolism" "Cluster 80: Oligodendrocytes - Myelination" 20 "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome, Basal body" "HPA037942: , HPA037943: , HPA075224: " "unprognostic (4.15e-2)" "unprognostic (3.57e-2)" "unprognostic (1.32e-1)" "unprognostic (2.87e-1)" "unprognostic (9.45e-2)" "unprognostic (5.51e-2)" "unprognostic (1.94e-1)" "unprognostic (4.31e-1)" "unprognostic (1.62e-2)" "potential prognostic favorable (4.07e-4)" "unprognostic (3.17e-1)" "unprognostic (6.97e-2)" "unprognostic (1.81e-1)" "unprognostic (5.84e-2)" "unprognostic (1.76e-1)" "unprognostic (2.82e-2)" "unprognostic (1.78e-2)" "unprognostic (1.42e-2)" "unprognostic (6.00e-3)" "unprognostic (1.54e-2)" "unprognostic (9.76e-2)" "unprognostic (2.34e-2)" "unprognostic (5.54e-3)" "unprognostic (3.81e-1)" "unprognostic (2.60e-2)" "unprognostic (1.74e-1)" "unprognostic (1.20e-1)" "unprognostic (1.04e-1)" "unprognostic (1.45e-1)" SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 18.2" "Cell type enhanced" "Detected in some" "cDC: 10.0;Hofbauer cells: 27.4;Innate lymphoid cells: 13.6;Kupffer cells: 91.2;Macrophages: 24.1;monocytes: 30.2;Neutrophils: 11.9;NK-cells: 17.4;Platelets: 8.4" "Cell type enriched" "Detected in some" 5 "Mononuclear phagocytes: 91.2" "Group enriched" "Detected in some" 18 "central nervous system macrophage: 5.2;leukocyte: 7.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.7" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 16 "Leukemia: 3.5;Myeloma: 4.5" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Cell type enriched" "Detected in single" 5962 "Macrophages: 596157.4" "Group enriched" "Detected in some" 10945 "bone marrow: 1182957.8;liver: 814221.3;lymphoid tissue: 1286358.5" "HPA075513, CAB080396" Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" "Cell adhesion" NA NA 80000 "Cluster 25: Non-specific - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Plasma membrane" Vesicles "CAB080396: , HPA075513: " "unprognostic (2.87e-2)" "unprognostic (6.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.93e-3)" "unprognostic (1.70e-1)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (3.39e-1)" "unprognostic (2.19e-1)" "unprognostic (5.24e-2)" "unprognostic (1.28e-1)" "unprognostic (4.53e-1)" "unprognostic (9.60e-2)" "unprognostic (2.08e-1)" "unprognostic (3.33e-2)" "unprognostic (4.38e-2)" "potential prognostic unfavorable (8.95e-4)" "unprognostic (4.36e-2)" "unprognostic (8.85e-2)" "unprognostic (3.48e-2)" "unprognostic (4.22e-1)" "unprognostic (1.13e-1)" "unprognostic (5.22e-2)" "unprognostic (9.99e-2)" "unprognostic (9.29e-2)" "unprognostic (3.53e-2)" "unprognostic (4.19e-2)" "unprognostic (1.14e-3)" "unprognostic (2.92e-1)" "unprognostic (2.18e-1)" SIK2 "DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2" ENSG00000170145 "Salt inducible kinase 2" Q9H0K1 11 111602449-111730855 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1896.4;Lactotrophs: 942.5;Salivary acinar cells: 802.5;Somatotrophs: 1639.8" "Cell type enhanced" "Detected in many" "Adipocytes: 1896.4;Pituitary endocrine cells: 1639.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 518503.8" "Tissue enriched" "Detected in some" "lymphoid tissue: 221277.6" "HPA016026, HPA071049" Approved Approved "Nucleoplasm,Nuclear speckles,Vesicles,Intermediate filaments,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 89: Adipocytes - Lipid metabolism" 25 "Nucleoplasm, Vesicles" "Nuclear speckles, Intermediate filaments, Cytosol" "HPA016026: , HPA071049: " "unprognostic (7.61e-3)" "unprognostic (1.02e-1)" "unprognostic (7.05e-2)" "unprognostic (1.46e-1)" "unprognostic (3.06e-1)" "unprognostic (2.74e-2)" "unprognostic (4.82e-2)" "unprognostic (1.94e-1)" "unprognostic (4.48e-2)" "unprognostic (8.94e-3)" "validated prognostic favorable (3.25e-10)" "validated prognostic favorable (1.19e-4)" "unprognostic (9.36e-3)" "unprognostic (1.65e-3)" "unprognostic (1.33e-2)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (9.51e-2)" "unprognostic (1.45e-1)" "unprognostic (2.49e-3)" "unprognostic (1.31e-2)" "unprognostic (2.48e-2)" "unprognostic (2.23e-1)" "unprognostic (9.66e-2)" "unprognostic (1.00e-2)" "unprognostic (1.39e-1)" "unprognostic (4.13e-2)" "unprognostic (1.17e-1)" "unprognostic (5.19e-1)" "unprognostic (5.62e-2)" "unprognostic (9.30e-2)" SIM1 bHLHe14 ENSG00000112246 "SIM bHLH transcription factor 1" P81133 6 100385009-100464921 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.7;kidney: 9.2;skeletal muscle: 3.3" "Cell type enhanced" "Detected in some" "Distal convoluted tubule cells: 372.1;Epididymal basal cells: 51.8;Epididymal efferent duct absorptive cells: 63.9;Loop of henle epithelial cells: 285.8;Pancreatic islet cells: 92.9;Papillary tip epithelial cells: 68.4;Renal collecting duct intercalated cells: 265.8;Renal collecting duct principal cells: 160.3;Renal connecting tubule cells: 245.0" "Cell type enhanced" "Detected in many" "Ductal cells: 265.8;Pancreatic islet cells: 92.9;Renal nephron cells: 372.1" "Cell type enriched" "Detected in some" 6 "mammillary body: 89.4" "Group enriched" "Detected in some" 4 "Kidney Chromophobe (TCGA): 10.7;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.3" "Group enriched" "Detected in some" 4 "hypothalamus: 9.2;midbrain: 2.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Kidney cancer: 2.3;ovarian cancer: 1.9" "Testis - Early spermatids" "Region enriched" "Detected in single" 8 "hypothalamus: 5.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA024385 Approved "Nuclear speckles" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 15: Kidney cancer - Membrane components" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 5 "Nuclear speckles" "HPA024385: " "unprognostic (2.05e-1)" "unprognostic (2.08e-2)" "unprognostic (2.58e-3)" "unprognostic (1.19e-3)" "unprognostic (1.85e-2)" SIM2 "bHLHe15, MGC119447, SIM" ENSG00000159263 "SIM bHLH transcription factor 2" Q14190 21 36699115-36749917 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 29.1;kidney: 64.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 99.7;Basal prostatic cells: 47.2;Esophageal apical cells: 76.6;Esophageal basal cells: 88.5;Esophageal suprabasal cells: 59.9;Foveolar cells: 38.8;Gastric chief cells: 40.4;Loop of henle epithelial cells: 357.3;Mucous neck cells: 79.8;Myonuclei: 50.5;Prostatic glandular cells: 85.0;Submucosal glandular cells: 41.9;Suprabasal keratinocytes: 46.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 76.6;Basal cells: 99.7;Gastric glandular cells: 79.8;Glandular cells: 85.0;Renal nephron cells: 357.3" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Prostate Adenocarcinoma (TCGA): 36.1;Stomach Adenocarcinoma (TCGA): 13.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 38.6" "Kidney - Ascending Loop of Henle cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in single" "hypothalamus: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA029295 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 72: Kidney - Transmembrane transport" "Cluster 29: Forebrain - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 5 "Nucleoplasm, Nuclear bodies" "HPA029295: " "unprognostic (3.13e-2)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (4.17e-1)" "potential prognostic favorable (5.67e-4)" "unprognostic (2.75e-2)" "unprognostic (1.28e-3)" "unprognostic (2.57e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-2)" "unprognostic (6.08e-3)" "unprognostic (5.38e-2)" "unprognostic (1.30e-1)" "unprognostic (2.86e-2)" "unprognostic (2.32e-2)" "unprognostic (3.82e-2)" "unprognostic (1.20e-3)" "unprognostic (3.03e-1)" "unprognostic (8.79e-2)" "unprognostic (2.27e-2)" "unprognostic (8.53e-2)" "unprognostic (1.35e-2)" "unprognostic (9.76e-2)" "unprognostic (3.05e-1)" "unprognostic (9.92e-2)" SIN3A "DKFZP434K2235, KIAA0700" ENSG00000169375 "SIN3 transcription regulator family member A" Q96ST3 15 75369379-75455842 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Transcription, Transcription regulation" Repressor "Cancer-related genes, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 244.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB004506, HPA047213, HPA062123" Enhanced Enhanced Nucleoplasm NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 39: Testis - Nuclear processes" "Cluster 15: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 149 Nucleoplasm "CAB004506: , HPA047213: , HPA062123: " "unprognostic (4.88e-2)" "unprognostic (1.73e-1)" "unprognostic (6.40e-2)" "unprognostic (4.31e-1)" "unprognostic (1.51e-1)" "unprognostic (1.36e-1)" "unprognostic (4.17e-1)" "unprognostic (3.95e-1)" "unprognostic (1.04e-1)" "unprognostic (1.81e-2)" "validated prognostic favorable (3.21e-5)" "validated prognostic favorable (8.33e-5)" "unprognostic (6.48e-2)" "potential prognostic unfavorable (4.33e-4)" "unprognostic (5.38e-3)" "unprognostic (6.69e-2)" "unprognostic (9.89e-2)" "unprognostic (1.83e-1)" "unprognostic (1.48e-2)" "unprognostic (1.12e-1)" "unprognostic (2.74e-1)" "unprognostic (6.92e-2)" "unprognostic (1.75e-2)" "unprognostic (2.80e-1)" "unprognostic (3.39e-2)" "unprognostic (1.65e-1)" "unprognostic (3.39e-1)" "unprognostic (3.00e-2)" "unprognostic (1.34e-1)" "unprognostic (4.67e-2)" "unprognostic (1.08e-1)" SIPA1L2 "KIAA1389, SPAR2" ENSG00000116991 "Signal induced proliferation associated 1 like 2" Q9P2F8 1 232397965-232630571 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia: 522.7;Neutrophils: 1155.9;Pituicytes/FSCs: 647.2;Pituitary stem cells: 504.1;Schwann cells: 522.9" "Cell type enhanced" "Detected in many" "Glial cells: 647.2;Neutrophils: 1155.9" "Cell type enhanced" "Detected in all" "midbrain-derived inhibitory: 664.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Fibroblasts_1, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 22064377.2;Cardiomyocytes: 9205868.8" "Tissue enriched" "Detected in some" "heart muscle: 876242.8" "HPA024181, HPA027224" Approved Approved "Nucleoplasm,Nuclear membrane,Nuclear bodies,Golgi apparatus" No NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 35 "Nucleoplasm, Nuclear membrane, Nuclear bodies" "Golgi apparatus" "HPA024181: , HPA027224: " "unprognostic (5.34e-2)" "unprognostic (6.66e-2)" "unprognostic (2.29e-2)" "unprognostic (9.70e-2)" "unprognostic (1.52e-2)" "unprognostic (9.97e-3)" "unprognostic (2.00e-1)" "unprognostic (9.37e-2)" "unprognostic (5.66e-2)" "unprognostic (6.13e-3)" "potential prognostic favorable (4.03e-5)" "unprognostic (4.68e-3)" "unprognostic (1.90e-3)" "unprognostic (7.75e-3)" "unprognostic (1.22e-1)" "unprognostic (1.36e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (6.38e-3)" "unprognostic (1.83e-2)" "unprognostic (4.97e-2)" "unprognostic (3.39e-2)" "unprognostic (9.80e-2)" "unprognostic (3.12e-1)" "unprognostic (1.26e-2)" "unprognostic (2.00e-1)" "unprognostic (1.24e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-1)" "unprognostic (8.90e-3)" "unprognostic (8.96e-3)" SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal amacrine cells: 1038.7" "Cell type enhanced" "Detected in all" "Neuronal cells: 1038.7" "Cell type enhanced" "Detected in all" "cerebellar inhibitory: 750.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "lung: 4780676.9" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 26 "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: , HPA045480: , HPA074988: " "unprognostic (1.50e-2)" "unprognostic (8.56e-2)" "unprognostic (3.13e-1)" "unprognostic (3.05e-2)" "unprognostic (1.02e-1)" "unprognostic (2.09e-2)" "unprognostic (3.85e-2)" "unprognostic (1.25e-1)" "unprognostic (1.99e-2)" "unprognostic (5.30e-2)" "unprognostic (1.25e-1)" "unprognostic (3.69e-2)" "unprognostic (2.47e-1)" "unprognostic (1.30e-2)" "unprognostic (3.41e-2)" "unprognostic (2.89e-1)" "unprognostic (6.65e-2)" "unprognostic (1.78e-1)" "unprognostic (1.15e-1)" "unprognostic (6.30e-2)" "unprognostic (1.91e-1)" "unprognostic (1.63e-1)" "unprognostic (3.36e-2)" "unprognostic (4.08e-2)" "unprognostic (6.50e-3)" "unprognostic (1.23e-1)" "unprognostic (1.46e-1)" "unprognostic (2.08e-1)" "unprognostic (3.06e-1)" "unprognostic (2.94e-2)" "unprognostic (6.14e-2)" SIRT1 SIR2L1 ENSG00000096717 "Sirtuin 1" Q96EB6 10 67884656-67918390 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Differentiation, Host-virus interaction, Myogenesis, Transcription, Transcription regulation" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 379.1" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 379.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 1499081.1;Granulosa cells: 2551230.4" "Group enriched" "Detected in some" 620 "bone marrow: 108650.1;lymphoid tissue: 39934.8;ovary: 37288.2" "CAB003855, HPA006295, HPA052351" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Mitochondria,Cytosol" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 225 Nucleoplasm "Nucleoli fibrillar center, Mitochondria, Cytosol" "CAB003855: , HPA006295: , HPA052351: " "unprognostic (2.69e-3)" "unprognostic (6.66e-2)" "unprognostic (1.67e-1)" "unprognostic (1.44e-2)" "unprognostic (2.25e-1)" "unprognostic (7.94e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (2.17e-5)" "unprognostic (1.12e-1)" "unprognostic (1.59e-1)" "potential prognostic favorable (2.32e-6)" "unprognostic (2.40e-3)" "unprognostic (1.14e-1)" "unprognostic (2.25e-1)" "unprognostic (3.58e-1)" "unprognostic (2.26e-1)" "unprognostic (2.11e-1)" "unprognostic (1.55e-1)" "unprognostic (3.02e-1)" "unprognostic (1.80e-1)" "unprognostic (5.89e-3)" "unprognostic (1.04e-1)" "unprognostic (6.90e-2)" "unprognostic (4.82e-2)" "unprognostic (2.06e-1)" "unprognostic (1.35e-1)" "unprognostic (1.11e-1)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.67e-1)" SIRT2 SIR2L ENSG00000068903 "Sirtuin 2" Q8IXJ6 19 38878555-38899862 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Autophagy, Cell cycle, Cell division, Differentiation, Immunity, Innate immunity, Meiosis, Mitosis, Neurogenesis, Transcription, Transcription regulation" Transferase "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 492.9;skeletal muscle: 306.9;tongue: 203.7" "Group enriched" "Detected in many" 4 "Oligodendrocyte progenitor cells: 132.5;Oligodendrocytes: 303.3" "Cell type enriched" "Detected in many" 5 "Glial cells: 303.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 721.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Skeletal myocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 392054159.1;Microglia and Neuropil: 128036823.7" "Tissue enriched" "Detected in all" "cerebral cortex: 170588900.2" "CAB004573, HPA011165" Approved Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 4: Non-specific - Transcription" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" 22 "Nucleoli, Cytosol" "Nucleoplasm, Plasma membrane" "CAB004573: , HPA011165: " "unprognostic (7.74e-2)" "unprognostic (4.23e-1)" "unprognostic (3.12e-2)" "unprognostic (6.02e-2)" "unprognostic (2.22e-1)" "unprognostic (4.83e-3)" "unprognostic (2.29e-3)" "unprognostic (7.65e-2)" "unprognostic (2.47e-2)" "unprognostic (1.84e-1)" "potential prognostic favorable (5.94e-6)" "unprognostic (1.62e-1)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (3.02e-2)" "unprognostic (2.82e-3)" "unprognostic (3.10e-1)" "unprognostic (7.14e-2)" "unprognostic (1.70e-1)" "unprognostic (8.56e-2)" "unprognostic (6.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.24e-1)" "unprognostic (3.98e-1)" "unprognostic (7.98e-2)" "unprognostic (3.57e-2)" "unprognostic (8.27e-2)" "unprognostic (9.71e-2)" "unprognostic (1.11e-1)" "unprognostic (2.50e-1)" "unprognostic (1.05e-2)" SIRT5 ENSG00000124523 "Sirtuin 5" Q9NXA8 6 13574227-13615158 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 118.4;Neutrophil progenitors: 125.8;Neutrophils: 138.9" "Cell type enhanced" "Detected in all" "Neutrophils: 138.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 58262331.5" "Tissue enhanced" "Detected in many" "skeletal muscle: 5522464.6" "HPA021798, HPA022002, HPA022992" Approved Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 76: Non-specific - Metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 8 Mitochondria "HPA021798: , HPA022002: , HPA022992: " "unprognostic (4.94e-2)" "unprognostic (4.77e-3)" "unprognostic (1.70e-1)" "unprognostic (7.94e-2)" "unprognostic (3.39e-2)" "unprognostic (3.47e-1)" "unprognostic (1.75e-2)" "unprognostic (2.06e-1)" "unprognostic (1.20e-1)" "unprognostic (9.07e-2)" "validated prognostic favorable (1.83e-6)" "validated prognostic favorable (2.84e-5)" "unprognostic (2.13e-3)" "unprognostic (2.75e-1)" "unprognostic (1.60e-2)" "unprognostic (1.20e-1)" "unprognostic (3.07e-1)" "unprognostic (1.42e-1)" "potential prognostic favorable (5.81e-4)" "potential prognostic favorable (4.81e-4)" "unprognostic (1.57e-1)" "unprognostic (5.00e-2)" "unprognostic (2.87e-1)" "unprognostic (8.89e-3)" "potential prognostic favorable (6.21e-7)" "unprognostic (8.51e-2)" "unprognostic (1.81e-2)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "unprognostic (4.59e-2)" "unprognostic (2.14e-1)" SIRT6 ENSG00000077463 "Sirtuin 6" Q8N6T7 19 4174109-4182566 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "Acyltransferase, Chromatin regulator, Developmental protein, DNA-binding, Glycosyltransferase, Nucleotidyltransferase, RNA-binding, Transferase" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Colonocytes: 261.6" "Cell type enriched" "Detected in many" 4 "Enterocytes: 261.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 263103.8;Neurons: 312106.3" "Tissue enriched" "Detected in single" 8366 "lymphoid tissue: 836604.2" "HPA049729, HPA071776" Supported Supported Nucleoplasm,Vesicles No No "Cluster 29: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 18: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 98 Nucleoplasm Vesicles "HPA049729: , HPA071776: " "unprognostic (1.33e-1)" "unprognostic (1.19e-1)" "unprognostic (2.38e-1)" "unprognostic (7.01e-3)" "unprognostic (2.53e-1)" "unprognostic (1.44e-1)" "unprognostic (2.41e-1)" "unprognostic (1.58e-1)" "unprognostic (4.38e-2)" "unprognostic (1.19e-1)" "unprognostic (1.90e-1)" "unprognostic (9.64e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (2.01e-2)" "unprognostic (1.14e-1)" "unprognostic (1.53e-1)" "unprognostic (8.53e-2)" "unprognostic (1.78e-1)" "unprognostic (3.84e-2)" "unprognostic (7.85e-2)" "unprognostic (1.95e-2)" "unprognostic (7.59e-2)" "unprognostic (6.28e-2)" "unprognostic (2.17e-1)" "unprognostic (1.07e-1)" "unprognostic (1.58e-2)" "unprognostic (2.01e-3)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (5.90e-2)" SIX1 DFNA23 ENSG00000126778 "SIX homeobox 1" Q15475 14 60643421-60658259 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Apoptosis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, Repressor" "Cancer-related genes, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 45.0;salivary gland: 48.1;skeletal muscle: 111.8;tongue: 43.2" "Cell type enhanced" "Detected in some" "Adipocytes: 75.2;Conjunctival goblet cells: 92.2;Endometrial secretory cells: 81.7;Gonadotrophs: 125.1;Lacrimal acinar cells: 136.8;Medullary thymic epithelial cells: 134.4;Myonuclei: 149.2;Myosatellite cells: 104.2;Pituitary stem cells: 110.1;Respiratory basal cells: 64.5;Respiratory ciliated cells: 88.5;Respiratory deuterosomal cells: 60.1;Respiratory secretory cells: 69.5;Salivary acinar cells: 89.1;Salivary duct cells: 68.1;Thymic myoid cells: 84.3" "Cell type enhanced" "Detected in many" "Acinar cells: 136.8;Myocytes: 149.2;Pituitary endocrine cells: 125.1;Secretory gland support: 134.4;Stem cells: 110.1" "Group enriched" "Detected in some" 35 "fibroblast: 17.3;pericyte: 28.3;vascular associated smooth muscle cell: 9.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Adipocytes (Breast), Lung - Respiratory ciliated cells, Testis - Spermatogonia" "Not detected" "Not detected" "Region enhanced" "Detected in some" "spinal cord: 5.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001893, CAB058690" Enhanced Supported Nucleoplasm,Nucleoli No No "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 22 Nucleoplasm Nucleoli "CAB058690: , HPA001893: " "unprognostic (7.73e-2)" "unprognostic (6.35e-2)" "unprognostic (2.81e-1)" "potential prognostic favorable (4.67e-4)" "unprognostic (5.46e-2)" "unprognostic (7.24e-2)" "unprognostic (1.16e-2)" "unprognostic (4.18e-2)" "unprognostic (7.55e-3)" "unprognostic (1.11e-3)" "potential prognostic unfavorable (3.04e-4)" "unprognostic (3.28e-3)" "unprognostic (7.30e-2)" "unprognostic (1.15e-1)" "unprognostic (1.65e-1)" "unprognostic (4.14e-2)" "unprognostic (5.56e-3)" "unprognostic (5.67e-1)" "unprognostic (7.36e-3)" "unprognostic (7.21e-2)" "unprognostic (9.34e-2)" "unprognostic (3.82e-1)" "unprognostic (3.35e-3)" SKA1 "C18orf24, MGC10200" ENSG00000154839 "Spindle and kinetochore associated complex subunit 1" Q96BD8 18 50375040-50394168 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 4.5" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 1.6;Early spermatids: 1.9;Erythrocyte progenitors: 7.0;Late primary spermatocytes: 1.2;Megakaryocyte progenitors: 3.4;Monocyte progenitors: 4.4;Plasma cells: 1.4" "Cell type enhanced" "Detected in some" "Erythrocytes: 7.0;Megakaryocytes: 3.4;Mononuclear phagocytes: 4.4" "Cell type enhanced" "Detected in some" "medium spiny neuron: 1.6;upper rhombic lip: 1.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Granulosa cells: 2729933.1" "Not detected" "Not detected" HPA045495 Approved Supported "Microtubules,Cytokinetic bridge,Primary cilium,Centriolar satellite,Basal body" Yes Yes "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 27 "Microtubules, Primary cilium" "Cytokinetic bridge, Centriolar satellite, Basal body" "HPA045495: " "unprognostic (1.98e-1)" "unprognostic (2.40e-2)" "unprognostic (1.17e-1)" "unprognostic (2.84e-1)" "unprognostic (3.30e-2)" "unprognostic (3.97e-1)" "unprognostic (4.56e-2)" "unprognostic (3.96e-2)" "unprognostic (1.15e-1)" "unprognostic (3.09e-3)" "potential prognostic unfavorable (1.28e-9)" "validated prognostic unfavorable (1.68e-6)" "validated prognostic unfavorable (1.20e-8)" "potential prognostic unfavorable (7.59e-5)" "unprognostic (1.29e-3)" "unprognostic (5.97e-3)" "unprognostic (2.47e-3)" "unprognostic (2.37e-2)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (8.72e-4)" "unprognostic (5.90e-3)" "unprognostic (1.79e-1)" "unprognostic (1.02e-2)" "unprognostic (6.30e-2)" "unprognostic (2.57e-3)" "unprognostic (4.34e-2)" "unprognostic (3.45e-1)" SKA3 "C13orf3, MGC4832, RAMA1" ENSG00000165480 "Spindle and kinetochore associated complex subunit 3" Q8IX90 13 21153595-21176552 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.5;lymphoid tissue: 11.3;testis: 5.9" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 29.5;Early primary spermatocytes: 29.7;Enteric transient amplifying cells: 16.6;Erythrocyte progenitors: 47.8;Esophageal basal cells: 22.1;Extravillous trophoblasts: 25.1;Gastric progenitor cells: 20.5;Megakaryocyte progenitors: 36.1;Migrating cytotrophoblasts: 20.6;Monocyte progenitors: 37.8;Oocytes: 27.6" "Cell type enhanced" "Detected in many" "Erythrocytes: 47.8;Megakaryocytes: 36.1;Mononuclear phagocytes: 37.8;Oocytes: 27.6;Spermatogenic cell types: 29.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1777 "Granulosa cells: 191606.1;Oocytes: 163820.8" "Tissue enriched" "Detected in single" 155 "bone marrow: 15529.4" "HPA039272, HPA039356, HPA061534" Approved Uncertain "Mitotic spindle,Centrosome,Cytosol" Yes Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 29: Forebrain - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 21 "Mitotic spindle, Centrosome" Cytosol "HPA039272: , HPA039356: , HPA061534: " "unprognostic (1.10e-2)" "unprognostic (6.00e-2)" "unprognostic (1.25e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (1.03e-1)" "unprognostic (2.88e-1)" "unprognostic (6.89e-3)" "unprognostic (1.44e-1)" "validated prognostic unfavorable (2.72e-6)" "validated prognostic unfavorable (9.75e-9)" "validated prognostic unfavorable (1.12e-4)" "validated prognostic unfavorable (2.54e-4)" "unprognostic (3.15e-2)" "unprognostic (5.96e-2)" "unprognostic (1.31e-1)" "unprognostic (1.19e-1)" "validated prognostic unfavorable (2.78e-4)" "validated prognostic unfavorable (2.22e-4)" "unprognostic (3.76e-2)" "unprognostic (7.48e-2)" "unprognostic (3.11e-2)" "unprognostic (7.15e-3)" "unprognostic (7.28e-2)" "unprognostic (8.01e-2)" SKIC2 "170A, DDX13, HLP, SKI2, SKI2W, SKIV2, SKIV2L, SKIV2L1" ENSG00000204351 "SKI2 subunit of superkiller complex" Q15477 6 31959116-31969818 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 16.0;Epicardial cells: 47.8" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 47.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 30.0" "Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA047122, HPA051959, HPA054419" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitotic spindle,Cytosol" Yes NA "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 17 "Nucleoplasm, Nuclear bodies" "Mitotic spindle, Cytosol" "HPA047122: , HPA051959: , HPA054419: " "unprognostic (4.96e-1)" "unprognostic (1.11e-1)" "unprognostic (2.10e-1)" "unprognostic (2.19e-2)" "unprognostic (3.76e-1)" "unprognostic (5.10e-2)" "unprognostic (2.11e-2)" "unprognostic (1.42e-1)" "unprognostic (3.96e-2)" "unprognostic (1.68e-3)" "unprognostic (3.01e-2)" "unprognostic (1.84e-1)" "unprognostic (1.90e-1)" "unprognostic (1.61e-1)" "unprognostic (1.10e-1)" "unprognostic (4.25e-2)" "unprognostic (1.94e-1)" "unprognostic (4.59e-1)" "unprognostic (7.12e-2)" "unprognostic (1.35e-1)" "unprognostic (3.07e-2)" "unprognostic (1.82e-1)" "unprognostic (1.10e-2)" "unprognostic (1.16e-2)" "unprognostic (9.55e-2)" "unprognostic (2.39e-1)" "unprognostic (1.83e-1)" "unprognostic (5.67e-2)" "unprognostic (2.21e-2)" "unprognostic (1.28e-1)" "unprognostic (2.12e-1)" SKP1 "EMC19, MGC34403, OCP-II, OCP2, p19A, SKP1A, TCEB1L" ENSG00000113558 "S-phase kinase associated protein 1" P63208 5 134148935-134176964 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB012982, HPA053745" Approved Approved "Nucleoplasm,Cytokinetic bridge,Primary cilium,Centrosome,Basal body,Cytosol" Yes No 1400000 "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 334 "Nucleoplasm, Cytosol" "Cytokinetic bridge, Primary cilium, Centrosome, Basal body" "CAB012982: , HPA053745: " "unprognostic (8.49e-2)" "unprognostic (2.63e-3)" "unprognostic (8.06e-3)" "unprognostic (2.35e-1)" "unprognostic (1.17e-2)" "unprognostic (3.81e-3)" "unprognostic (4.67e-2)" "unprognostic (6.78e-2)" "unprognostic (2.53e-3)" "unprognostic (8.29e-2)" "potential prognostic favorable (1.85e-9)" "unprognostic (5.96e-3)" "unprognostic (2.26e-1)" "unprognostic (1.06e-3)" "unprognostic (3.28e-2)" "unprognostic (3.11e-2)" "unprognostic (1.72e-2)" "unprognostic (7.29e-2)" "unprognostic (1.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.16e-2)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (1.84e-2)" "unprognostic (2.97e-2)" "unprognostic (9.58e-3)" "unprognostic (1.83e-1)" "unprognostic (6.85e-3)" "unprognostic (1.96e-1)" "unprognostic (1.99e-1)" "unprognostic (5.45e-2)" SLA2 "C20orf156, FLJ21992, SLAP-2" ENSG00000101082 "Src like adaptor 2" Q9H6Q3 20 36612318-36646196 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.7;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 69.8;Megakaryocytes: 166.9;NK-cells: 257.5;pDCs: 96.7;Platelets: 447.0;T-cells: 124.3;Thymocytes: 45.7" "Cell type enhanced" "Detected in many" "dendritic cells: 96.7;Megakaryocytes: 166.9;NK-cells: 257.5;Platelets: 447.0;T-cells: 124.3" "Cell type enriched" "Detected in many" 11 "leukocyte: 76.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "gdT-cell: 28.8;MAIT T-cell: 24.1;memory CD4 T-cell: 23.8;memory CD8 T-cell: 27.0;naive CD4 T-cell: 21.8;naive CD8 T-cell: 30.5;NK-cell: 39.2;plasmacytoid DC: 48.4;T-reg: 33.4" "Group enriched" "Detected in many" 8 "dendritic cells: 48.4;NK-cells: 39.2;T-cells: 33.4" "Cancer enriched" "Detected in some" 9 "Leukemia: 15.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Lung - NK-cells (Lung), Minor Salivary Gland - T-cells, Prostate - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 1167 "bone marrow: 107818.9;lymphoid tissue: 125511.1" "HPA053746, HPA058217" Approved "Nucleoplasm,Golgi apparatus,Vesicles" No NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 6 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA053746: , HPA058217: " "unprognostic (8.65e-2)" "unprognostic (3.28e-3)" "unprognostic (7.87e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (1.51e-1)" "unprognostic (5.18e-2)" "unprognostic (1.55e-1)" "unprognostic (3.74e-3)" "unprognostic (3.17e-2)" "unprognostic (2.45e-1)" "unprognostic (1.18e-1)" "unprognostic (3.55e-2)" "unprognostic (2.95e-3)" "unprognostic (6.30e-2)" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (1.07e-2)" "unprognostic (8.53e-2)" "unprognostic (4.64e-2)" "unprognostic (1.40e-3)" "unprognostic (2.09e-1)" "unprognostic (9.01e-2)" "unprognostic (9.16e-2)" "unprognostic (5.29e-2)" "unprognostic (2.69e-2)" "unprognostic (3.26e-2)" SLAIN2 "FLJ21611, KIAA1458" ENSG00000109171 "SLAIN motif family member 2" Q9P270 4 48341529-48426201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 563.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 563.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Keratinocytes: 5287786.4" "Group enriched" "Detected in many" "intestine: 771435.5;liver: 1879863.3;lymphoid tissue: 907662.5;Stomach: 1434376.3" "HPA035824, HPA063599" Approved Supported "Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA 96000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 24 "Centrosome, Cytosol" "Primary cilium tip, Basal body" "HPA035824: , HPA063599: " "unprognostic (2.28e-1)" "unprognostic (3.03e-2)" "unprognostic (1.20e-1)" "unprognostic (2.25e-3)" "unprognostic (1.96e-2)" "unprognostic (1.29e-1)" "unprognostic (2.64e-1)" "unprognostic (9.19e-3)" "unprognostic (9.49e-2)" "potential prognostic unfavorable (4.06e-5)" "validated prognostic favorable (1.63e-6)" "validated prognostic favorable (8.85e-5)" "unprognostic (7.10e-2)" "unprognostic (8.47e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (9.28e-3)" "unprognostic (3.28e-1)" "unprognostic (4.42e-1)" "unprognostic (5.81e-2)" "unprognostic (8.99e-2)" "unprognostic (2.77e-3)" "unprognostic (4.86e-2)" "unprognostic (1.42e-1)" "unprognostic (1.22e-1)" "unprognostic (1.95e-1)" "unprognostic (2.02e-1)" "unprognostic (1.61e-1)" "unprognostic (3.68e-1)" "unprognostic (9.26e-2)" "unprognostic (1.65e-1)" SLBP HBP ENSG00000163950 "Stem-loop binding protein" Q14493 4 1692731-1712344 "Essential proteins, Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 382.6;Early primary spermatocytes: 367.7;Oocytes: 419.1" "Cell type enhanced" "Detected in all" "Oocytes: 419.1;Spermatogenic cell types: 382.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 589506.5" "Tissue enriched" "Detected in single" 5507 "lymphoid tissue: 550701.9" "HPA019254, HPA061670" Supported Supported Nucleoplasm,Nucleoli,Cytosol Yes Yes "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 75: Non-specific - Chaperones and protein folding" 25 "Nucleoplasm, Nucleoli" Cytosol "HPA019254: , HPA061670: " "unprognostic (2.68e-3)" "unprognostic (1.46e-2)" "unprognostic (7.44e-2)" "unprognostic (3.26e-1)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "unprognostic (6.43e-2)" "unprognostic (2.70e-1)" "unprognostic (7.43e-3)" "unprognostic (3.19e-2)" "potential prognostic favorable (3.31e-5)" "unprognostic (2.71e-2)" "unprognostic (1.29e-3)" "validated prognostic unfavorable (8.19e-5)" "validated prognostic unfavorable (3.88e-5)" "unprognostic (3.49e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (1.69e-1)" "unprognostic (2.04e-1)" "unprognostic (2.51e-1)" "unprognostic (8.99e-3)" "unprognostic (1.68e-2)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (5.75e-4)" "unprognostic (1.83e-2)" "unprognostic (8.72e-2)" "unprognostic (3.06e-3)" "unprognostic (1.61e-1)" "unprognostic (1.83e-1)" "unprognostic (3.84e-1)" "unprognostic (3.46e-2)" SLC11A2 "DCT1, DMT-1, DMT1, FLJ37416, NRAMP2" ENSG00000110911 "Solute carrier family 11 member 2" P49281 12 50979401-51028566 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA032139, HPA032140" Uncertain Supported Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 Mitochondria "HPA032139: , HPA032140: " "unprognostic (7.51e-2)" "unprognostic (7.35e-3)" "unprognostic (1.26e-1)" "unprognostic (6.82e-3)" "unprognostic (2.95e-1)" "unprognostic (1.07e-1)" "unprognostic (3.45e-1)" "unprognostic (1.11e-1)" "unprognostic (2.96e-1)" "unprognostic (2.44e-1)" "potential prognostic favorable (8.22e-4)" "unprognostic (6.77e-2)" "unprognostic (1.41e-2)" "unprognostic (5.21e-2)" "unprognostic (7.26e-2)" "unprognostic (6.94e-3)" "unprognostic (1.77e-1)" "unprognostic (5.98e-2)" "unprognostic (6.56e-2)" "unprognostic (4.15e-2)" "unprognostic (2.09e-2)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (1.85e-1)" "unprognostic (4.51e-3)" "unprognostic (6.79e-3)" "unprognostic (7.16e-2)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (1.07e-2)" "unprognostic (7.91e-2)" SLC12A4 KCC1 ENSG00000124067 "Solute carrier family 12 member 4" Q9UP95 16 67943474-67969601 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 52.1;Syncytiotrophoblasts: 81.3" "Cell type enhanced" "Detected in many" "Trophoblast cells: 81.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 43.6;pericyte: 29.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.7" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic islets: 2145669.9" "Tissue enhanced" "Detected in many" "pancreas: 3939175.0" "HPA041138, HPA048239" Approved Approved "Nucleoplasm,Cell Junctions,Cytokinetic bridge,Primary cilium" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 18 "Nucleoplasm, Cell Junctions" "Cytokinetic bridge, Primary cilium" "HPA041138: , HPA048239: " "unprognostic (2.43e-3)" "unprognostic (5.42e-2)" "unprognostic (9.39e-2)" "unprognostic (1.46e-1)" "unprognostic (1.51e-1)" "unprognostic (1.74e-2)" "unprognostic (1.71e-1)" "unprognostic (1.58e-1)" "unprognostic (1.15e-2)" "unprognostic (5.54e-2)" "potential prognostic favorable (2.11e-8)" "unprognostic (1.23e-3)" "potential prognostic favorable (1.47e-4)" "unprognostic (1.13e-2)" "unprognostic (6.31e-3)" "unprognostic (9.70e-2)" "unprognostic (1.36e-1)" "unprognostic (1.60e-3)" "unprognostic (3.01e-1)" "unprognostic (2.60e-2)" "unprognostic (2.68e-1)" "unprognostic (2.60e-2)" "unprognostic (1.85e-2)" "unprognostic (4.19e-2)" "unprognostic (1.43e-1)" "unprognostic (2.69e-3)" "unprognostic (1.54e-1)" "unprognostic (3.29e-2)" "unprognostic (3.55e-1)" "unprognostic (1.72e-1)" "unprognostic (1.14e-1)" SLC12A6 "ACCPN, KCC3, KCC3A, KCC3B" ENSG00000140199 "Solute carrier family 12 member 6" Q9UHW9 15 34229784-34338060 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Symport, Transport" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 2078.3" "Cell type enriched" "Detected in all" 6 "Neutrophils: 2078.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 15.2;neutrophil: 23.5" "Lineage enriched" "Detected in many" 7 "granulocytes: 23.5" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1483107.3;Proximal tubules: 1235022.1" "Tissue enhanced" "Detected in many" "bone marrow: 7872026.7" HPA034563 Uncertain Approved Vesicles,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 "Vesicles, Cytosol" "HPA034563: " "unprognostic (1.14e-1)" "unprognostic (1.73e-1)" "unprognostic (6.78e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (3.26e-2)" "unprognostic (1.29e-2)" "unprognostic (1.52e-1)" "unprognostic (8.72e-3)" "unprognostic (8.58e-2)" "unprognostic (3.32e-3)" "potential prognostic favorable (1.45e-7)" "unprognostic (9.54e-3)" "unprognostic (2.59e-3)" "unprognostic (8.40e-2)" "unprognostic (1.02e-2)" "unprognostic (1.47e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.64e-1)" "unprognostic (1.16e-1)" "unprognostic (5.69e-2)" "unprognostic (6.41e-2)" "unprognostic (1.31e-3)" "unprognostic (7.55e-2)" "unprognostic (1.30e-1)" "unprognostic (1.62e-2)" "unprognostic (2.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (4.93e-3)" "unprognostic (1.04e-1)" SLC13A5 "INDY, NACT" ENSG00000141485 "Solute carrier family 13 member 5" Q86YT5 17 6684719-6713377 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 393.9" "Cell type enhanced" "Detected in some" "Astrocytes: 42.5;Bergmann glia: 29.1;Hepatocytes: 440.0;Salivary acinar cells: 242.2;Salivary myoepithelial cells: 97.6" "Cell type enhanced" "Detected in many" "Acinar cells: 242.2;Hepatocytes: 440.0;Secretory gland support: 97.6" "Group enriched" "Detected in some" 4 "astrocyte: 36.0;Bergmann glia: 28.8" "Cancer enriched" "Detected in many" 13 "Liver Hepatocellular Carcinoma (TCGA): 91.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "Bile duct cancer: 2.9;liver cancer: 6.5" "Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Hepatocytes: 447971.9" "Group enriched" "Detected in some" 10234 "cerebral cortex: 1399995.7;liver: 646778.6" HPA044343 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 18: Liver cancer - Metabolism" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 17 "Nucleoplasm, Plasma membrane" "HPA044343: " "unprognostic (6.76e-2)" "unprognostic (2.26e-1)" "unprognostic (1.95e-1)" "unprognostic (1.18e-1)" "unprognostic (1.09e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (7.33e-4)" "unprognostic (1.99e-1)" "unprognostic (1.21e-2)" "unprognostic (3.78e-1)" "unprognostic (6.33e-2)" "unprognostic (2.71e-3)" "unprognostic (5.15e-2)" "unprognostic (6.06e-2)" "unprognostic (1.43e-1)" SLC16A1 "MCT, MCT1" ENSG00000155380 "Solute carrier family 16 member 1" P53985 1 112911847-112957593 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 54.6;Early spermatids: 46.3;Ependymal cells: 50.0;Late spermatids: 57.6;Müller glia: 56.0;Oligodendrocytes: 38.1;Proximal tubule cells: 30.4;Retinal pigment epithelial cells: 38.4;Rod photoreceptor cells: 27.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 54.6;Glial cells: 56.0;Spermatogenic cell types: 57.6" "Cell type enhanced" "Detected in all" "endothelial cell: 178.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Granulosa cells: 39173056.4" "Tissue enhanced" "Detected in many" "liver: 41042996.2" "HPA003324, CAB017489, HPA071055, CAB079035" Enhanced Supported Enhanced "Plasma membrane,Cell Junctions" NA NA 15000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 47: Endothelial cells - Vasculature" "Cluster 34: Testis cancer - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 27 "Plasma membrane, Cell Junctions" "CAB017489: , CAB079035: , HPA003324: , HPA071055: " "unprognostic (1.30e-2)" "unprognostic (1.01e-1)" "unprognostic (7.38e-2)" "unprognostic (5.28e-3)" "unprognostic (1.44e-1)" "unprognostic (3.94e-1)" "unprognostic (4.66e-2)" "unprognostic (3.48e-2)" "unprognostic (1.59e-2)" "potential prognostic unfavorable (5.73e-6)" "unprognostic (8.11e-3)" "unprognostic (1.60e-1)" "unprognostic (4.02e-2)" "unprognostic (6.52e-3)" "unprognostic (2.50e-3)" "potential prognostic unfavorable (2.39e-6)" "unprognostic (1.76e-2)" "unprognostic (7.00e-2)" "unprognostic (1.40e-1)" "unprognostic (2.87e-2)" "unprognostic (2.24e-1)" "potential prognostic unfavorable (4.85e-4)" "unprognostic (2.50e-1)" "unprognostic (1.53e-2)" "unprognostic (2.59e-2)" "unprognostic (2.35e-1)" "unprognostic (8.65e-2)" "unprognostic (1.06e-1)" "unprognostic (3.32e-1)" "unprognostic (1.26e-2)" "unprognostic (5.01e-2)" SLC16A13 MCT13 ENSG00000174327 "Solute carrier family 16 member 13" Q7RTY0 17 7036015-7040117 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 33.8" "Cell type enhanced" "Detected in many" "Paneth cells: 30.9;Proximal tubule cells: 18.8;Tuft cells: 23.1" "Cell type enhanced" "Detected in many" "Secretory gland support: 30.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA065245 Supported "Golgi apparatus,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 16 "Golgi apparatus" Cytosol "HPA065245: " "unprognostic (7.21e-2)" "unprognostic (2.30e-1)" "unprognostic (1.17e-1)" "unprognostic (2.07e-2)" "unprognostic (4.45e-2)" "unprognostic (2.00e-1)" "unprognostic (4.21e-2)" "unprognostic (1.74e-2)" "unprognostic (1.09e-1)" "unprognostic (5.88e-3)" "potential prognostic favorable (4.13e-5)" "unprognostic (2.23e-2)" "unprognostic (2.00e-1)" "unprognostic (1.27e-1)" "unprognostic (2.45e-2)" "unprognostic (7.85e-3)" "unprognostic (2.15e-1)" "unprognostic (7.10e-2)" "unprognostic (2.01e-2)" "unprognostic (1.04e-1)" "unprognostic (4.91e-1)" "unprognostic (2.92e-3)" "unprognostic (5.12e-3)" "unprognostic (2.61e-1)" "unprognostic (2.14e-1)" "unprognostic (3.88e-3)" "unprognostic (7.13e-2)" "unprognostic (8.49e-2)" "unprognostic (1.70e-1)" "unprognostic (1.57e-2)" "unprognostic (1.47e-1)" SLC16A14 "FLJ30794, MCT14" ENSG00000163053 "Solute carrier family 16 member 14" Q7RTX9 2 230034982-230068993 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 17.5" "Cell type enriched" "Detected in many" 13 "Retinal pigment epithelial cells: 852.6" "Cell type enriched" "Detected in many" 13 "Pigment cells: 852.6" "Cell type enhanced" "Detected in all" "endothelial cell: 192.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "eosinophil: 11.3" "Lineage enriched" "Detected in single" 24 "granulocytes: 11.3" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 21.7" "Adipose subcutaneous - Endothelial cells, Kidney - Endothelial cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA040518 Uncertain Approved "Endoplasmic reticulum" No No "Cluster 22: Eosinophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 7: Liver cancer - Metabolism" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "Endoplasmic reticulum" "HPA040518: " "unprognostic (2.46e-2)" "unprognostic (1.46e-1)" "unprognostic (2.65e-1)" "unprognostic (1.71e-1)" "unprognostic (6.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-3)" "unprognostic (9.13e-3)" "unprognostic (3.75e-1)" "unprognostic (2.76e-3)" "unprognostic (7.07e-3)" "unprognostic (9.94e-3)" "unprognostic (2.30e-2)" "unprognostic (5.82e-2)" "unprognostic (2.99e-2)" "unprognostic (3.83e-2)" "unprognostic (5.10e-2)" "unprognostic (2.74e-3)" "unprognostic (3.65e-2)" "unprognostic (1.29e-1)" "unprognostic (3.30e-2)" "unprognostic (2.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (1.72e-1)" "unprognostic (6.83e-2)" "unprognostic (1.26e-1)" "unprognostic (1.16e-2)" "unprognostic (2.50e-2)" SLC16A4 "MCT4, MCT5" ENSG00000168679 "Solute carrier family 16 member 4" O15374 1 110362851-110391082 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "kidney: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 110.6;Cardiomyocytes: 160.5;Myonuclei: 110.1;Proximal tubule cells: 125.7;Renal collecting duct principal cells: 96.8;Renal connecting tubule cells: 79.6" "Cell type enhanced" "Detected in many" "Myocytes: 160.5;Renal nephron cells: 125.7" "Cell type enhanced" "Detected in all" "endothelial cell: 76.0" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 62.8;Kidney Renal Papillary Cell Carcinoma (TCGA): 63.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.5" "Lineage enriched" "Detected in single" 4 "B-cells: 1.5" "Cancer enhanced" "Detected in all" "Kidney cancer: 31.1" "Adrenal gland - Fibroblasts, Colon - Enteric glia cells, Heart muscle - Fibroblasts, Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Glomeruli: 2337510.5;Proximal tubules: 3604190.4" "Not detected" "Not detected" "HPA046986, HPA060163" Approved Approved "Microtubules,Cytokinetic bridge,Cytosol" Yes NA "Cluster 18: Non-specific - Translation" "Cluster 72: Kidney - Transmembrane transport" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Microtubules, Cytosol" "Cytokinetic bridge" "HPA046986: , HPA060163: " "unprognostic (2.13e-1)" "unprognostic (1.36e-1)" "unprognostic (4.83e-2)" "unprognostic (9.52e-2)" "unprognostic (2.10e-1)" "unprognostic (2.06e-1)" "unprognostic (3.05e-1)" "unprognostic (9.07e-2)" "unprognostic (1.96e-1)" "validated prognostic favorable (4.88e-7)" "validated prognostic favorable (1.89e-5)" "unprognostic (8.94e-2)" "unprognostic (3.43e-2)" "unprognostic (2.88e-3)" "unprognostic (1.55e-2)" "unprognostic (4.46e-2)" "unprognostic (2.19e-2)" "unprognostic (1.94e-2)" "unprognostic (2.58e-1)" "unprognostic (2.76e-3)" "unprognostic (3.40e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-1)" "unprognostic (1.05e-1)" "unprognostic (6.44e-2)" "unprognostic (3.59e-1)" "unprognostic (2.52e-2)" "unprognostic (2.15e-1)" "unprognostic (6.69e-2)" "unprognostic (2.11e-2)" SLC16A8 "MCT3, REMP" ENSG00000100156 "Solute carrier family 16 member 8" O95907 22 38078134-38084184 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.4" "Cell type enriched" "Detected in many" 19 "Retinal pigment epithelial cells: 532.9" "Cell type enriched" "Detected in many" 19 "Pigment cells: 532.9" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 4.7" "Prostate - Prostate glandular cells, Spleen - Fibroblasts_2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA075017 Approved Approved "Intermediate filaments,Focal adhesion sites" No NA "Cluster 2: Non-specific - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" "Focal adhesion sites" "Intermediate filaments" "HPA075017: " "unprognostic (6.73e-2)" "unprognostic (2.90e-1)" "unprognostic (6.84e-2)" "unprognostic (1.70e-1)" "unprognostic (2.57e-2)" SLC16A9 "C10orf36, FLJ43803, MCT9" ENSG00000165449 "Solute carrier family 16 member 9" Q7RTY1 10 59650764-59736002 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 142.9;kidney: 178.4" "Group enriched" "Detected in many" 4 "Adrenal cortex cells: 850.0;Proximal tubule cells: 1103.2" "Group enriched" "Detected in many" 4 "Adrenal endocrine cells: 850.0;Renal nephron cells: 1103.2" "Group enriched" "Detected in many" 4 "astrocyte: 179.0;Bergmann glia: 66.5;choroid plexus epithelial cell: 162.3;ependymal cell: 102.2;upper rhombic lip: 67.1" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 45.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2979 "Glomeruli: 332537.0;Proximal tubules: 263313.3" "Not detected" "Not detected" HPA049286 Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 3 Nucleoplasm "Cell Junctions" "HPA049286: " "unprognostic (4.71e-2)" "unprognostic (1.31e-1)" "unprognostic (2.80e-1)" "unprognostic (1.92e-1)" "unprognostic (1.94e-1)" "unprognostic (2.02e-2)" "unprognostic (2.38e-3)" "unprognostic (3.90e-3)" "unprognostic (6.00e-2)" "potential prognostic favorable (3.21e-8)" "unprognostic (1.34e-3)" "unprognostic (3.46e-3)" "unprognostic (7.19e-2)" "unprognostic (3.00e-2)" "unprognostic (1.97e-1)" "unprognostic (2.08e-2)" "potential prognostic favorable (4.66e-5)" "unprognostic (5.28e-2)" "unprognostic (1.46e-2)" "unprognostic (2.19e-1)" "unprognostic (1.01e-1)" "unprognostic (6.10e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-3)" "unprognostic (2.45e-1)" "unprognostic (6.72e-2)" "unprognostic (1.18e-2)" "unprognostic (3.26e-1)" "unprognostic (9.50e-2)" SLC17A8 "DFNA25, VGLUT3" ENSG00000179520 "Solute carrier family 17 member 8" Q8NDX2 12 100357074-100422055 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hearing, Ion transport, Neurotransmitter transport, Phosphate transport, Sodium transport, Symport, Transport" "Chloride channel, Ion channel" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 4.9;lymphoid tissue: 1.3" "Cell type enhanced" "Detected in some" "Endometrial ciliated cells: 27.2;Enterocytes: 46.1;Ependymal cells: 11.6;Epididymal efferent duct ciliated cells: 7.1;Extravillous trophoblasts: 12.4;Granulosa cells: 7.3;Kupffer cells: 7.2;Oligodendrocyte progenitor cells: 7.3;Other brain neurons: 18.2;Paneth cells: 11.6;Prostatic club cells: 11.1;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 27.2;Enterocytes: 46.1;Neuronal cells: 18.2" "Cell type enhanced" "Detected in some" "CGE interneuron: 16.4;ependymal cell: 18.8" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "cerebral cortex: 24.1;midbrain: 18.5;pons: 14.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatic stellate cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 2736 "Microglia and Neuropil: 273639.5" "Tissue enriched" "Detected in single" 5594 "cerebral cortex: 559448.0" "HPA038870, CAB079058" Supported Approved "Endoplasmic reticulum" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 24: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Endoplasmic reticulum" "CAB079058: , HPA038870: " "unprognostic (1.12e-2)" SLC18A2 "SVAT, SVMT, VMAT2" ENSG00000165646 "Solute carrier family 18 member A2" Q05940 10 117241093-117279430 "Disease related genes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Disease variant, Dystonia, FDA approved drug targets, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.4;cervix: 28.1" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 138.3;Endometrial glandular cells: 307.0;Mast cells: 647.6;Neuroendocrine cells: 79.0;Other brain neurons: 67.3;Pancreatic islet cells: 59.1;Platelets: 87.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 138.3;Glandular cells: 307.0;Mast cells: 647.6" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 32.5" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 8.2" "Group enriched" "Detected in many" 12 "hypothalamus: 47.5;midbrain: 173.0;pons: 150.4" "Immune cell enriched" "Detected in some" 15 "basophil: 59.5" "Lineage enriched" "Detected in many" 15 "granulocytes: 59.5" "Group enriched" "Detected in some" 5 "Leukemia: 9.7;Neuroblastoma: 7.0" "Adipose subcutaneous - Mast cells, Adipose visceral - Mast cells, Adrenal gland - Adrenal medulla cells, Colon - Mast cells, Lung - Mast cells, Testis - Spermatogonia" "Region enhanced" "Detected in many" "midbrain: 62.8" "Region enriched" "Detected in all" 4 "midbrain: 145.2" "Cell type enriched" "Detected in single" 2786 "Pancreatic islets: 278587.1" "Not detected" "Not detected" HPA073224 Enhanced Approved Vesicles,Centrosome NA NA "Cluster 41: Basophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 49: HMC-1 - Innate immune response" "Cluster 58: Mast cells - Allergic inflammatory responses" 10 "Vesicles, Centrosome" "HPA073224: " "unprognostic (1.02e-2)" "unprognostic (3.81e-1)" "unprognostic (1.96e-2)" "unprognostic (8.09e-2)" "potential prognostic favorable (8.93e-7)" "unprognostic (1.12e-2)" "unprognostic (2.97e-2)" "unprognostic (1.24e-2)" "potential prognostic favorable (6.60e-5)" "unprognostic (2.19e-1)" "unprognostic (2.10e-1)" "unprognostic (1.69e-1)" "unprognostic (1.27e-2)" "unprognostic (2.07e-1)" "unprognostic (3.41e-1)" "unprognostic (2.57e-3)" "unprognostic (4.07e-2)" "unprognostic (9.69e-2)" SLC1A5 "AAAT, ASCT2, M7V1, RDRC" ENSG00000105281 "Solute carrier family 1 member 5" Q15758 19 46774883-46788594 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Host-virus interaction, Symport, Transport" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 157.5;Extravillous trophoblasts: 177.6;Prostatic hillock cells: 188.0" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 30.1;leukocyte: 12.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 96.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary gland ductal cells, Prostate - Prostate basal glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 9721532.6" "Tissue enhanced" "Detected in many" "pancreas: 10775574.8" "HPA035239, HPA035240" Enhanced Supported "Plasma membrane,Centriolar satellite,Basal body" NA NA 27000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 32: Non-specific - Cell proliferation" "Cluster 103: Non-specific - Basic cellular processes" 33 "Plasma membrane" "Centriolar satellite, Basal body" "HPA035239: , HPA035240: " "unprognostic (1.16e-1)" "unprognostic (1.19e-3)" "unprognostic (1.32e-1)" "unprognostic (1.23e-1)" "unprognostic (1.79e-2)" "unprognostic (9.91e-3)" "unprognostic (1.30e-1)" "unprognostic (1.88e-2)" "unprognostic (6.83e-2)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (2.20e-7)" "unprognostic (1.12e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.14e-10)" "unprognostic (4.21e-3)" "unprognostic (1.46e-3)" "unprognostic (1.06e-2)" "unprognostic (6.65e-2)" "unprognostic (1.39e-1)" "unprognostic (8.07e-3)" "unprognostic (2.91e-2)" "unprognostic (2.71e-2)" "unprognostic (1.27e-1)" "unprognostic (2.53e-2)" "unprognostic (1.03e-1)" "unprognostic (3.04e-1)" "unprognostic (8.69e-3)" "unprognostic (1.52e-2)" "unprognostic (1.34e-1)" "unprognostic (8.91e-2)" "unprognostic (3.88e-1)" SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950033-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 105.2" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 18.2;Brain inhibitory neurons: 20.3;Early spermatids: 52.6;Extravillous trophoblasts: 17.4;Late primary spermatocytes: 48.4;Late spermatids: 115.6;Other brain neurons: 18.9;Retinal horizontal cells: 24.0;Sertoli cells: 41.7;Syncytiotrophoblasts: 58.1" "Cell type enhanced" "Detected in some" "Neuronal cells: 24.0;Reproductive supporting cells: 41.7;Spermatogenic cell types: 115.6;Trophoblast cells: 58.1" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 7 "Bladder Urothelial Carcinoma (TCGA): 45.4" "Region enriched" "Detected in all" 5 "cerebellum: 159.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder cancer: 8.1;breast cancer: 8.4" "Pituitary gland - Gonadotropes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells, Testis - Sertoli cells" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 70.8" "Group enriched" "Detected in some" "Microglia and Neuropil: 319031.4;Neurons: 1207350.4" "Not detected" "Not detected" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 19: Cerebellar purkinje cells - Neurotransmission & signaling" "Plasma membrane" "Intermediate filaments" "HPA041505: , HPA044066: " "unprognostic (1.05e-3)" "unprognostic (7.21e-2)" "unprognostic (4.29e-1)" "unprognostic (3.63e-1)" "unprognostic (1.53e-1)" "unprognostic (1.83e-1)" "potential prognostic favorable (9.69e-5)" "unprognostic (7.24e-3)" "unprognostic (2.47e-1)" "unprognostic (5.07e-2)" "unprognostic (4.62e-2)" "potential prognostic favorable (4.47e-4)" "unprognostic (1.34e-1)" "unprognostic (1.96e-3)" SLC22A14 "OCTL2, ORCTL4" ENSG00000144671 "Solute carrier family 22 member 14" Q9Y267 3 38282294-38318575 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 10.9" "Group enriched" "Detected in many" 6 "Early spermatids: 92.3;Late primary spermatocytes: 48.2;Late spermatids: 174.0" "Cell type enriched" "Detected in many" 10 "Spermatogenic cell types: 174.0" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA037556 Approved "Perinuclear theca,Connecting piece,Mid piece,Principal piece" NA NA "Cluster 67: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 56: Non-specific - Sensory perception" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "Connecting piece, Mid piece, Principal piece" "Perinuclear theca" "HPA037556: " SLC22A3 "EMT, OCT3" ENSG00000146477 "Solute carrier family 22 member 3" O75751 6 160348378-160452577 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 77.1" "Cell type enhanced" "Detected in many" "Adipocytes: 106.3;Adrenal cortex cells: 162.2;Alveolar cells type 2: 250.6;Hepatocytes: 115.7;Leydig cells: 208.6;Myonuclei: 192.6;Oligodendrocyte progenitor cells: 135.2;Peritubular myoid cells: 125.5;Prostatic glandular cells: 647.1;Salivary acinar cells: 271.4;Smooth muscle cells: 151.6;Transitional alveolar cells: 244.3;Vascular smooth muscle cells: 185.1" "Cell type enhanced" "Detected in many" "Acinar cells: 271.4;Alveolar cells: 250.6;Glandular cells: 647.1" "Cell type enhanced" "Detected in many" "oligodendrocyte precursor cell: 196.0;vascular associated smooth muscle cell: 313.0" "Cancer enhanced" "Detected in many" "Prostate Adenocarcinoma (TCGA): 28.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 27.8;prostate cancer: 30.0" "Adipose visceral - Adipocytes (Visceral), Heart muscle - Smooth muscle cells, Lung - Alveolar cells type 2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 4179236.2" "Low tissue specificity" "Detected in many" HPA029750 Approved Approved Vesicles,Cytosol NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" Vesicles Cytosol "HPA029750: " "unprognostic (2.08e-1)" "potential prognostic favorable (1.41e-4)" "potential prognostic unfavorable (6.44e-5)" "unprognostic (3.46e-1)" "unprognostic (2.07e-2)" "unprognostic (1.27e-1)" "unprognostic (6.94e-2)" "unprognostic (3.27e-1)" "unprognostic (1.49e-1)" "unprognostic (6.51e-3)" "potential prognostic favorable (1.38e-4)" "unprognostic (7.63e-2)" "unprognostic (8.85e-2)" "unprognostic (7.36e-3)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (7.78e-2)" "unprognostic (1.10e-2)" "unprognostic (2.11e-2)" "unprognostic (1.46e-1)" "unprognostic (4.25e-2)" "unprognostic (3.24e-1)" "unprognostic (4.38e-2)" "unprognostic (1.14e-2)" "potential prognostic unfavorable (4.57e-4)" SLC25A14 "BMCP1, UCP5" ENSG00000102078 "Solute carrier family 25 member 14" O95258 X 130339888-130373361 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 46.5;Respiratory ciliated cells: 44.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 618956.8;Granulosa cells: 619660.0;Microglia and Neuropil: 1689382.7;Neurons: 2300065.3;Oocytes: 1465989.9" "Tissue enriched" "Detected in single" 9916 "cerebral cortex: 991591.6" HPA060316 Approved Mitochondria NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 1 Mitochondria "HPA060316: " "unprognostic (1.28e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (2.21e-1)" "unprognostic (6.68e-3)" "unprognostic (1.12e-1)" "unprognostic (9.49e-2)" "unprognostic (1.92e-1)" "unprognostic (2.34e-2)" "unprognostic (1.16e-1)" "unprognostic (1.79e-1)" "potential prognostic favorable (2.86e-8)" "unprognostic (2.80e-1)" "unprognostic (3.12e-1)" "unprognostic (3.70e-3)" "unprognostic (5.43e-2)" "unprognostic (3.38e-2)" "unprognostic (2.92e-2)" "unprognostic (2.45e-1)" "unprognostic (1.24e-1)" "unprognostic (2.78e-2)" "unprognostic (3.20e-2)" "unprognostic (6.37e-3)" "unprognostic (1.65e-1)" "unprognostic (3.20e-2)" "unprognostic (1.36e-1)" "unprognostic (3.76e-1)" "unprognostic (1.29e-1)" "unprognostic (9.91e-2)" "unprognostic (1.42e-1)" "unprognostic (6.76e-2)" "unprognostic (2.78e-1)" SLC25A18 ENSG00000182902 "Solute carrier family 25 member 18" Q9H1K4 22 17563450-17590995 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 139.0;liver: 106.7" "Group enriched" "Detected in many" 4 "Astrocytes: 345.2;Bergmann glia: 99.3;Hepatocytes: 123.5" "Group enriched" "Detected in many" 5 "Glial cells: 345.2;Hepatocytes: 123.5" "Cell type enriched" "Detected in many" 4 "astrocyte: 421.4" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 35.2;Liver Hepatocellular Carcinoma (TCGA): 26.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Adipocytes (Subcutaneous), Breast - Adipocytes (Breast), Prostate - Prostate glandular cells, Spleen - Fibroblasts_2, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 22536686.5;Hepatocytes: 40754246.4;Microglia and Neuropil: 14538791.2" "Tissue enriched" "Detected in some" "intestine: 33622246.8" HPA068110 Approved Nucleoplasm,Mitochondria NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 28: Astrocytes - Homeostasis & neuron support" 7 Mitochondria Nucleoplasm "HPA068110: " "unprognostic (5.20e-2)" "unprognostic (6.95e-2)" "unprognostic (8.60e-2)" "unprognostic (1.87e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-2)" "unprognostic (3.92e-3)" "unprognostic (7.68e-3)" "unprognostic (1.54e-1)" "unprognostic (6.95e-2)" "unprognostic (2.33e-3)" "unprognostic (2.38e-1)" "unprognostic (2.51e-1)" SLC25A20 "CAC, CACT" ENSG00000178537 "Solute carrier family 25 member 20" O43772 3 48856926-48898904 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 138.7" "Cell type enhanced" "Detected in many" "Enterocytes: 73.7;Hepatocytes: 92.2;Myonuclei: 94.8" "Cell type enhanced" "Detected in all" "Hepatocytes: 92.2;Myocytes: 94.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 64.4" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 120504395.7" "Tissue enhanced" "Detected in many" "liver: 106917499.3" "HPA016862, HPA029863" Approved Approved Mitochondria,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 19: Astrocytes - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" "Mitochondria, Cytosol" "HPA016862: , HPA029863: " "unprognostic (2.09e-1)" "unprognostic (4.42e-2)" "unprognostic (4.46e-1)" "unprognostic (1.32e-1)" "unprognostic (1.68e-1)" "unprognostic (2.22e-1)" "unprognostic (3.00e-2)" "potential prognostic unfavorable (3.01e-6)" "unprognostic (9.79e-2)" "unprognostic (2.27e-2)" "potential prognostic favorable (6.12e-5)" "unprognostic (1.55e-2)" "unprognostic (3.69e-3)" "unprognostic (1.61e-1)" "unprognostic (1.16e-1)" "unprognostic (3.69e-2)" "unprognostic (2.68e-1)" "unprognostic (2.15e-1)" "unprognostic (2.55e-1)" "unprognostic (1.12e-1)" "unprognostic (5.16e-2)" "unprognostic (2.37e-2)" "unprognostic (6.35e-3)" "unprognostic (3.08e-1)" "unprognostic (1.83e-1)" "unprognostic (1.28e-1)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.52e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-1)" SLC25A22 "EIEE3, FLJ13044, GC-1, GC1, NET44" ENSG00000177542 "Solute carrier family 25 member 22" Q9H936 11 790475-798281 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.1;pancreas: 82.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.3;Oocytes: 50.7;Retinal bipolar cells: 101.0" "Cell type enhanced" "Detected in many" "Neuronal cells: 101.0;Oocytes: 50.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 16494653.6;Microglia and Neuropil: 17512226.2;Neurons: 13314071.7;Pancreas epithelial cells: 7838650.3;Pancreatic islets: 7084501.5" "Group enriched" "Detected in many" "cerebral cortex: 7997435.3;intestine: 7143780.2;pancreas: 5419620.1;Stomach: 2958940.5" HPA014662 Approved Uncertain Nucleoplasm,Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 27: Cerebellum - Synaptic function" "Cluster 51: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 17 Mitochondria Nucleoplasm "HPA014662: " "unprognostic (1.96e-1)" "unprognostic (5.75e-2)" "unprognostic (2.52e-2)" "unprognostic (3.56e-2)" "unprognostic (3.88e-2)" "unprognostic (1.95e-1)" "unprognostic (3.43e-3)" "unprognostic (5.37e-2)" "unprognostic (1.02e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-3)" "potential prognostic unfavorable (3.83e-4)" "unprognostic (2.76e-1)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (9.59e-2)" "unprognostic (1.78e-3)" "potential prognostic unfavorable (7.53e-5)" "unprognostic (2.37e-2)" "unprognostic (6.99e-3)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (1.42e-1)" "unprognostic (3.54e-3)" "unprognostic (7.83e-2)" "unprognostic (4.70e-1)" "unprognostic (2.11e-1)" "unprognostic (2.54e-1)" "unprognostic (1.47e-2)" "unprognostic (7.51e-2)" "unprognostic (1.41e-3)" "unprognostic (1.09e-1)" SLC25A26 ENSG00000144741 "Solute carrier family 25 member 26" Q70HW3 3 66133610-66388116 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 50.2;Bergmann glia: 58.1;Brain excitatory neurons: 70.7;Brain inhibitory neurons: 62.2;Choroid plexus epithelial cells: 71.2;Distal convoluted tubule cells: 82.5;Loop of henle epithelial cells: 72.7;Microglia: 87.0;Oligodendrocyte progenitor cells: 60.0;Oligodendrocytes: 87.2;Other brain neurons: 56.1;Papillary tip epithelial cells: 54.9;Podocytes: 68.7;Proximal tubule cells: 77.1;Renal collecting duct intercalated cells: 68.4;Renal collecting duct principal cells: 63.3;Renal connecting tubule cells: 79.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 71.2;Ductal cells: 79.9;Glial cells: 87.2;Neuronal cells: 70.7;Renal nephron cells: 82.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 156877.1;Large ducts: 118694.2;Oocytes: 334288.1" "Not detected" "Not detected" HPA026887 Supported Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 102: Non-specific - Mixed function" Mitochondria "HPA026887: " "unprognostic (4.48e-2)" "unprognostic (4.15e-1)" "unprognostic (4.68e-3)" "unprognostic (1.60e-1)" "unprognostic (1.14e-1)" "unprognostic (2.89e-1)" "unprognostic (3.35e-1)" "unprognostic (9.13e-2)" "unprognostic (5.11e-2)" "unprognostic (4.46e-2)" "potential prognostic favorable (4.02e-7)" "unprognostic (1.86e-2)" "unprognostic (2.61e-2)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (8.12e-4)" "unprognostic (1.49e-1)" "unprognostic (8.35e-3)" "unprognostic (1.79e-1)" "unprognostic (3.72e-1)" "unprognostic (2.16e-1)" "unprognostic (8.83e-2)" "unprognostic (4.42e-2)" "unprognostic (1.36e-1)" "unprognostic (2.47e-1)" "unprognostic (1.43e-2)" "unprognostic (3.25e-2)" "unprognostic (1.68e-2)" "unprognostic (1.12e-1)" "unprognostic (2.00e-1)" "unprognostic (2.58e-1)" "unprognostic (1.95e-1)" SLC25A3 PHC ENSG00000075415 "Solute carrier family 25 member 3" Q00325 12 98593591-98606379 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 1205.5;Parietal cells: 1451.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 468028465.3" "Low tissue specificity" "Detected in all" HPA045709 Supported Mitochondria NA NA 340000 "Cluster 33: Non-specific - ATP binding" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 25 Mitochondria "HPA045709: " "unprognostic (1.23e-2)" "unprognostic (1.94e-1)" "unprognostic (9.43e-2)" "unprognostic (3.05e-2)" "potential prognostic favorable (9.58e-4)" "unprognostic (1.89e-1)" "unprognostic (3.18e-2)" "unprognostic (4.12e-1)" "unprognostic (1.02e-2)" "unprognostic (7.95e-2)" "potential prognostic favorable (2.31e-5)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" "unprognostic (7.99e-3)" "potential prognostic unfavorable (9.79e-7)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (2.96e-2)" "unprognostic (8.06e-2)" "unprognostic (2.41e-1)" "unprognostic (4.10e-3)" "unprognostic (1.44e-2)" "unprognostic (2.56e-1)" "unprognostic (3.43e-2)" "unprognostic (3.86e-2)" "unprognostic (6.47e-2)" "unprognostic (5.90e-2)" "unprognostic (2.12e-1)" "unprognostic (2.13e-1)" "unprognostic (4.47e-1)" "unprognostic (2.77e-1)" "unprognostic (1.75e-1)" SLC25A42 MGC26694 ENSG00000181035 "Solute carrier family 25 member 42" Q86VD7 19 19063994-19113030 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 76.0" "Cell type enhanced" "Detected in many" "Hepatocytes: 88.7;Myonuclei: 182.5;Proximal tubule cells: 182.0;Retinal bipolar cells: 111.4;Rod photoreceptor cells: 78.2" "Cell type enhanced" "Detected in many" "Myocytes: 182.5;Renal nephron cells: 182.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 2.8;MAIT T-cell: 1.5;memory B-cell: 3.3;memory CD4 T-cell: 1.6;memory CD8 T-cell: 2.4;naive B-cell: 3.2;naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.5;NK-cell: 1.8;T-reg: 1.7" "Group enriched" "Detected in many" 6 "B-cells: 3.3;NK-cells: 1.8;T-cells: 2.8" "Cancer enhanced" "Detected in all" "Myeloma: 22.5" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Minor Salivary Gland - Minor salivary glandular cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 6064668.5;Proximal tubules: 10105462.9" "Tissue enhanced" "Detected in some" "liver: 135418.1;lymphoid tissue: 257289.8" HPA049449 Approved Supported Mitochondria Yes No "Cluster 16: Non-specific - Cell proliferation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 55: Myocytes - Oxidative muscle function" 3 Mitochondria "HPA049449: " "unprognostic (1.23e-1)" "unprognostic (1.74e-1)" "unprognostic (5.14e-3)" "unprognostic (3.12e-3)" "unprognostic (9.57e-2)" "unprognostic (2.94e-2)" "unprognostic (1.75e-1)" "unprognostic (2.50e-2)" "unprognostic (1.27e-3)" "unprognostic (8.74e-3)" "potential prognostic favorable (8.43e-8)" "unprognostic (1.36e-3)" "unprognostic (3.02e-3)" "potential prognostic favorable (9.81e-4)" "unprognostic (2.67e-3)" "potential prognostic favorable (3.35e-4)" "unprognostic (2.94e-1)" "unprognostic (3.17e-1)" "unprognostic (3.37e-3)" "unprognostic (7.87e-2)" "unprognostic (3.02e-2)" "unprognostic (1.01e-2)" "unprognostic (4.21e-2)" "unprognostic (1.33e-2)" "unprognostic (2.41e-1)" "unprognostic (6.88e-2)" "unprognostic (1.77e-1)" "unprognostic (1.95e-2)" "unprognostic (6.35e-2)" "unprognostic (1.83e-3)" "unprognostic (2.21e-1)" SLC25A43 ENSG00000077713 "Solute carrier family 25 member 43" Q8WUT9 X 119399336-119454478 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 239.7;Esophageal suprabasal cells: 178.0;Fibro-adipogenic progenitors: 144.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 239.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035188, HPA078530" Uncertain Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 36: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" Cytosol "HPA035188: , HPA078530: " "unprognostic (3.25e-1)" "unprognostic (1.70e-3)" "unprognostic (3.89e-1)" "unprognostic (1.06e-1)" "unprognostic (8.79e-2)" "unprognostic (1.49e-1)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (2.40e-4)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (3.25e-4)" "unprognostic (1.22e-3)" "unprognostic (4.90e-3)" "unprognostic (2.51e-2)" "unprognostic (2.21e-3)" "unprognostic (3.53e-2)" "unprognostic (1.41e-2)" "potential prognostic unfavorable (5.96e-4)" "unprognostic (2.89e-1)" "unprognostic (5.12e-2)" "unprognostic (2.58e-2)" "unprognostic (2.32e-1)" "unprognostic (1.08e-2)" "unprognostic (3.21e-2)" "unprognostic (3.57e-1)" "unprognostic (1.57e-1)" "unprognostic (1.47e-1)" "unprognostic (5.41e-2)" "unprognostic (5.54e-2)" "unprognostic (2.10e-1)" "unprognostic (6.87e-3)" "unprognostic (5.50e-2)" SLC26A3 "CLD, DRA" ENSG00000091138 "Solute carrier family 26 member 3" P40879 7 107765467-107803225 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "intestine: 1050.9" "Group enriched" "Detected in many" 4 "Colonocytes: 4022.8;Enterocytes: 1364.6" "Cell type enriched" "Detected in all" 7 "Enterocytes: 4022.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" 13 "Colon Adenocarcinoma (TCGA): 77.5;Rectum Adenocarcinoma (TCGA): 94.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 25 "colorectal cancer: 16.6" "Breast - Breast glandular cells, Colon - Colon enterocytes, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA036055 Enhanced Approved Acrosome NA NA "Cluster 77: Intestine - Digestion" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 1 Acrosome "HPA036055: " "unprognostic (1.49e-2)" "unprognostic (2.15e-1)" "unprognostic (3.43e-2)" "unprognostic (2.87e-2)" "unprognostic (1.30e-3)" "unprognostic (4.94e-2)" "unprognostic (1.55e-1)" "unprognostic (5.30e-2)" "unprognostic (4.19e-2)" "unprognostic (2.10e-2)" "unprognostic (1.20e-1)" "unprognostic (2.66e-2)" SLC26A8 TAT1 ENSG00000112053 "Solute carrier family 26 member 8" Q96RN1 6 35943516-36024868 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Differentiation, Ion transport, Meiosis, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 41.2" "Group enriched" "Detected in many" 4 "Late primary spermatocytes: 152.1;Neutrophil progenitors: 104.7;Neutrophils: 268.2" "Group enriched" "Detected in many" 6 "Neutrophils: 268.2;Spermatogenic cell types: 152.1" "Low cell type specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 11 "neutrophil: 2.5" "Lineage enriched" "Detected in single" 11 "granulocytes: 2.5" "Not detected" "Not detected" "Adipose visceral - Neutrophils, Heart muscle - Neutrophils, Lung - Neutrophils_2, Minor Salivary Gland - Minor salivary glandular cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enhanced" "Detected in some" "fallopian tube: 3069125.6;Stomach: 3677988.5" "HPA038080, HPA038081, HPA061393" Enhanced Approved Acrosome,Annulus NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 24: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 Annulus Acrosome "HPA038080: , HPA038081: , HPA061393: " "unprognostic (2.49e-1)" "unprognostic (6.16e-2)" SLC27A3 "ACSVL3, FATP3, MGC4365" ENSG00000143554 "Solute carrier family 27 member 3" Q5K4L6 1 153774354-153780157 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Epididymal principal cells: 146.8" "Cell type enriched" "Detected in many" 5 "Reproductive supporting cells: 146.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 53.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "dendritic cells: 7.4;granulocytes: 12.6;monocytes: 11.1" "Cancer enriched" "Detected in many" 5 "skin cancer: 20.9" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Alveolar cell types: 32456355.5" "Tissue enhanced" "Detected in many" "skin: 49305750.9" "HPA067508, CAB080514, CAB080517" Enhanced Approved "Endoplasmic reticulum,Mitochondria" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 20 "Endoplasmic reticulum, Mitochondria" "CAB080514: , CAB080517: , HPA067508: " "unprognostic (1.90e-1)" "unprognostic (1.60e-1)" "unprognostic (1.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.74e-1)" "unprognostic (2.18e-1)" "unprognostic (3.61e-2)" "potential prognostic unfavorable (1.31e-4)" "unprognostic (2.14e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-1)" "unprognostic (4.81e-2)" "unprognostic (8.36e-2)" "unprognostic (2.05e-1)" "unprognostic (1.14e-1)" "unprognostic (3.21e-2)" "unprognostic (3.26e-1)" "unprognostic (1.76e-1)" "unprognostic (5.12e-2)" "unprognostic (2.88e-2)" "potential prognostic favorable (2.64e-4)" "unprognostic (2.29e-2)" "unprognostic (4.43e-3)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.85e-2)" "unprognostic (2.01e-1)" "unprognostic (1.38e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-2)" SLC27A6 "ACSVL2, FACVL2, FATP6, VLCS-H1" ENSG00000113396 "Solute carrier family 27 member 6" Q9Y2P4 5 128538013-129033642 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.0;fallopian tube: 20.0;heart muscle: 22.0" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 85.6;Cardiomyocytes: 342.4;Cytotrophoblasts: 97.2;Ependymal cells: 99.6;Extravillous trophoblasts: 63.4;Migrating cytotrophoblasts: 139.7;Müller glia: 73.5;Myosatellite cells: 84.3;Pituicytes/FSCs: 228.1;Pituitary stem cells: 70.8;Sertoli cells: 156.6" "Cell type enhanced" "Detected in many" "Glial cells: 228.1;Myocytes: 342.4;Reproductive supporting cells: 156.6;Trophoblast cells: 139.7" "Group enriched" "Detected in many" 4 "ependymal cell: 117.2;LAMP5-LHX6 and Chandelier: 124.7;MGE interneuron: 88.9;midbrain-derived inhibitory: 242.9;splatter: 70.0" "Cancer enriched" "Detected in many" 9 "Thyroid Carcinoma (TCGA): 37.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 5.1" "Colon - Colon enteroendocrine cells, Heart muscle - Cardiomyocytes, Skin - Hair cortex cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Capillaries: 15290733.3;Cardiomyocytes: 21009922.0;Fallopian tube cells: 5493927.6" "Group enriched" "Detected in some" "fallopian tube: 32419541.8;heart muscle: 55654750.3" HPA008987 Approved Approved "Nuclear bodies" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 43: Hindbrain - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 "Nuclear bodies" "HPA008987: " "unprognostic (5.46e-3)" "potential prognostic favorable (7.92e-5)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" "unprognostic (2.52e-1)" "unprognostic (1.33e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (2.57e-1)" "unprognostic (8.92e-2)" "unprognostic (2.24e-1)" SLC28A2 "CNT2, HCNT2, HsT17153, SPNT1" ENSG00000137860 "Solute carrier family 28 member 2" O43868 15 45252234-45277846 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "intestine: 86.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 56.7;Colonocytes: 46.4;Cytotrophoblasts: 20.1;Enteric stem cells: 31.7;Enteric transient amplifying cells: 39.2;Enterocytes: 63.3;Foveolar cells: 135.9;Mucous neck cells: 38.5;Myonuclei: 21.3" "Cell type enhanced" "Detected in many" "Enterocytes: 63.3;Gastric glandular cells: 135.9;Myocytes: 56.7;Proliferating cells: 39.2" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 10 "Gastric cancer: 7.6" "Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Glomeruli: 327194.3" "Tissue enriched" "Detected in single" 25654 "intestine: 2565366.7" "HPA046068, HPA055623" Enhanced Uncertain Vesicles NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 68: Foveolar cells - Mucosal defense" 1 Vesicles "HPA046068: , HPA055623: " "unprognostic (4.96e-2)" "unprognostic (3.93e-2)" "unprognostic (2.40e-2)" "unprognostic (1.20e-3)" "unprognostic (1.80e-3)" "unprognostic (1.88e-1)" "unprognostic (1.40e-1)" "unprognostic (1.54e-1)" "unprognostic (9.74e-2)" "unprognostic (6.20e-2)" "unprognostic (1.04e-1)" "unprognostic (2.19e-1)" "unprognostic (8.09e-2)" SLC29A3 "ENT3, FLJ11160, hENT3" ENSG00000198246 "Solute carrier family 29 member 3" Q9BZD2 10 71319259-71381423 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 57.1;Extravillous trophoblasts: 62.1;Hofbauer cells: 33.8;Kupffer cells: 36.9;Late spermatids: 34.5;Microglia: 75.3;Migrating cytotrophoblasts: 57.0;Oocytes: 36.8;Syncytiotrophoblasts: 35.8" "Cell type enhanced" "Detected in many" "Glial cells: 75.3;Trophoblast cells: 62.1" "Cell type enriched" "Detected in many" 6 "central nervous system macrophage: 95.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Kidney - Fibroblasts, Spleen - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Macrophages: 2554770.3;T-cells: 1201231.1" "Tissue enriched" "Detected in some" "lymphoid tissue: 519838.9" "HPA046085, HPA054976, HPA057905" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 63: Cytotrophoblasts - Basic cellular functions" "Golgi apparatus, Vesicles" "HPA046085: , HPA054976: , HPA057905: " "unprognostic (1.38e-1)" "unprognostic (2.43e-2)" "unprognostic (1.57e-1)" "unprognostic (9.54e-2)" "unprognostic (8.95e-2)" "unprognostic (1.43e-1)" "unprognostic (1.68e-1)" "unprognostic (2.28e-2)" "unprognostic (7.73e-2)" "unprognostic (1.45e-1)" "unprognostic (7.54e-2)" "unprognostic (2.84e-1)" "validated prognostic unfavorable (2.33e-5)" "validated prognostic unfavorable (5.85e-4)" "unprognostic (2.27e-2)" "unprognostic (8.33e-2)" "unprognostic (5.63e-2)" "unprognostic (7.79e-2)" "unprognostic (1.00e-1)" "unprognostic (5.90e-2)" "unprognostic (3.03e-1)" "unprognostic (1.13e-1)" "unprognostic (1.38e-1)" "unprognostic (1.01e-1)" "unprognostic (2.16e-1)" "unprognostic (1.14e-2)" "unprognostic (6.37e-2)" "unprognostic (2.05e-2)" "unprognostic (3.98e-2)" "unprognostic (3.42e-2)" SLC29A4 "ENT4, FLJ34923" ENSG00000164638 "Solute carrier family 29 member 4" Q7RTT9 7 5274369-5306912 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 40.7;brain: 32.2;choroid plexus: 35.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 74.5;Bergmann glia: 52.4;Choroid plexus epithelial cells: 75.6;Neuroendocrine cells: 112.1;Oocytes: 59.9;Pancreatic islet cells: 66.3;Retinal amacrine cells: 61.6;Retinal horizontal cells: 210.4;Retinal pigment epithelial cells: 89.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 74.5;Ciliated cells: 75.6;Enteroendocrine cells: 112.1;Neuronal cells: 210.4;Pigment cells: 89.5" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 91.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Neuroblastoma: 39.9" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal medulla cells, Breast - Adipocytes (Breast), Pancreas - Alpha cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 28 "Oocytes: 2775.4" "Not detected" "Not detected" HPA052829 Approved "Microtubules,Cytokinetic bridge" Yes No "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" "Microtubules, Cytokinetic bridge" "HPA052829: " "unprognostic (1.41e-1)" "unprognostic (1.92e-1)" "unprognostic (9.72e-2)" "unprognostic (1.95e-1)" "unprognostic (1.31e-2)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (8.36e-4)" "unprognostic (3.77e-1)" "unprognostic (7.78e-2)" "unprognostic (1.96e-1)" "unprognostic (1.30e-2)" "unprognostic (1.66e-2)" "unprognostic (3.96e-3)" "unprognostic (1.10e-2)" "unprognostic (1.45e-2)" "unprognostic (2.77e-1)" "unprognostic (3.14e-1)" "unprognostic (9.22e-2)" "unprognostic (1.20e-3)" "unprognostic (1.73e-2)" "unprognostic (1.09e-1)" "unprognostic (1.32e-3)" "unprognostic (1.63e-2)" "unprognostic (1.95e-1)" "unprognostic (2.22e-1)" "unprognostic (3.69e-3)" "unprognostic (7.57e-2)" "potential prognostic unfavorable (5.62e-4)" "unprognostic (1.79e-1)" "unprognostic (1.91e-3)" "unprognostic (2.54e-2)" SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT-1, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 92.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 987.3;Esophageal apical cells: 672.8;Extravillous trophoblasts: 730.6;Migrating cytotrophoblasts: 755.2;Müller glia: 484.8;Ocular epithelial cells: 855.1;Prostatic hillock cells: 375.5;Retinal pigment epithelial cells: 362.4;Syncytiotrophoblasts: 2979.0;Urothelial cells: 457.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 672.8;Barrier epithelial cells: 855.1;Trophoblast cells: 2979.0" "Cell type enriched" "Detected in all" 8 "endothelial cell: 678.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary gland basal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cell types: 81249790.0" "Low tissue specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane,Centriolar satellite" No No 2500000 "Cluster 14: Non-specific - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 47: Endothelial cells - Vasculature" "Cluster 15: Kidney cancer - Membrane components" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 90 "Plasma membrane" "Centriolar satellite" "CAB002759: , HPA031345: , HPA058494: " "unprognostic (1.47e-1)" "unprognostic (1.82e-1)" "unprognostic (6.77e-3)" "unprognostic (2.23e-3)" "unprognostic (3.13e-2)" "unprognostic (1.92e-2)" "unprognostic (4.46e-2)" "unprognostic (2.70e-3)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (7.39e-4)" "unprognostic (7.25e-3)" "unprognostic (3.93e-1)" "potential prognostic unfavorable (7.22e-4)" "validated prognostic unfavorable (2.32e-6)" "validated prognostic unfavorable (9.77e-4)" "validated prognostic unfavorable (5.40e-9)" "validated prognostic unfavorable (3.54e-4)" "unprognostic (5.29e-3)" "unprognostic (3.59e-2)" "unprognostic (2.92e-2)" "unprognostic (5.33e-2)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (2.14e-3)" "unprognostic (1.90e-1)" "unprognostic (2.44e-1)" "unprognostic (8.35e-2)" "unprognostic (8.37e-3)" "unprognostic (2.89e-2)" "unprognostic (2.38e-1)" "unprognostic (1.65e-3)" "unprognostic (1.64e-1)" SLC2A2 "GLUT-2, GLUT2" ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 781.9" "Cell type enhanced" "Detected in some" "Cholangiocytes: 141.1;Enterocytes: 226.3;Hepatocytes: 749.7;Proximal tubule cells: 56.5" "Cell type enhanced" "Detected in some" "Ductal cells: 141.1;Enterocytes: 226.3;Hepatocytes: 749.7" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 3.6;fibroblast: 4.6;oligodendrocyte: 6.1" "Cancer enriched" "Detected in some" 9 "Liver Hepatocellular Carcinoma (TCGA): 135.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 4.6;Kidney cancer: 6.4;liver cancer: 4.0" "Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Hepatocytes: 161122939.8" "Tissue enriched" "Detected in some" "liver: 218468742.6" "CAB010444, HPA028997, HPA069490" Enhanced Supported "Plasma membrane,Mid piece,Principal piece" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 15: Kidney cancer - Membrane components" "Cluster 93: Hepatocytes - Bile production & excretion" 3 "Plasma membrane, Mid piece, Principal piece" "CAB010444: , HPA028997: , HPA069490: " "potential prognostic favorable (1.10e-5)" "unprognostic (7.97e-2)" "unprognostic (7.92e-2)" "potential prognostic favorable (1.70e-5)" "unprognostic (1.46e-2)" "unprognostic (3.32e-1)" "unprognostic (2.02e-2)" SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 91.5;intestine: 102.6;skeletal muscle: 73.9;testis: 71.3" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 32.5;Early spermatids: 51.2;Enterocytes: 211.9;Hematopoietic stem cells: 48.5;Late primary spermatocytes: 158.2;Microglia: 179.4;Myonuclei: 35.3;Neutrophil progenitors: 80.2;Plasma cells: 38.7" "Cell type enhanced" "Detected in many" "Enterocytes: 211.9;Glial cells: 179.4;Neutrophils: 80.2;Spermatogenic cell types: 158.2" "Cell type enriched" "Detected in many" 33 "central nervous system macrophage: 213.3" "Group enriched" "Detected in many" 5 "Glioblastoma Multiforme (TCGA): 33.2;Kidney Renal Clear Cell Carcinoma (TCGA): 55.3" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in many" 8 "Leukemia: 40.5;lymphoma: 53.5;Myeloma: 32.2" "Adrenal gland - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Macrophages, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 3246407.3;Proximal tubules: 12858076.9" "Group enriched" "Detected in some" "cerebral cortex: 1080764.7;intestine: 1608321.7;kidney: 647462.7" "HPA005449, HPA075145" Enhanced Supported "Plasma membrane,Mid piece,Principal piece" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 12 "Plasma membrane" "Mid piece, Principal piece" "HPA005449: , HPA075145: " "unprognostic (1.66e-1)" "unprognostic (2.67e-1)" "unprognostic (2.25e-1)" "unprognostic (1.30e-1)" "unprognostic (2.19e-1)" "unprognostic (2.27e-1)" "unprognostic (2.66e-2)" "unprognostic (6.38e-2)" "unprognostic (7.38e-2)" "potential prognostic favorable (5.25e-4)" "unprognostic (4.50e-1)" "unprognostic (3.61e-1)" "unprognostic (2.66e-3)" "unprognostic (1.30e-1)" "unprognostic (2.01e-1)" "unprognostic (6.03e-2)" "unprognostic (1.08e-2)" "unprognostic (3.49e-1)" "unprognostic (5.42e-2)" "unprognostic (3.82e-1)" "unprognostic (3.62e-2)" "unprognostic (7.44e-2)" "unprognostic (9.17e-2)" "unprognostic (3.29e-3)" "unprognostic (2.65e-3)" "unprognostic (2.52e-1)" "unprognostic (2.78e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 55 "kidney: 145.2" "Cell type enriched" "Detected in some" 25 "Proximal tubule cells: 181.7" "Cell type enriched" "Detected in some" 25 "Renal nephron cells: 181.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Kidney Renal Clear Cell Carcinoma (TCGA): 3.9;Kidney Renal Papillary Cell Carcinoma (TCGA): 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Proximal tubules: 1622430.9" "Tissue enriched" "Detected in single" 455 "intestine: 45518.3" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 47: Leukemia - Hemostasis" "Cluster 88: Proximal tubular cells - Transmembrane transport" 1 "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: , HPA077175: " "potential prognostic favorable (1.78e-6)" "unprognostic (1.13e-3)" "unprognostic (1.23e-1)" SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 709.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 867.2;Alveolar cells type 2: 1909.3;Breast lactating cells: 291.0;Endometrial glandular cells: 419.7;Endometrial secretory cells: 444.3;Respiratory ciliated cells: 218.0;Transitional alveolar cells: 1120.7" "Cell type enriched" "Detected in many" 4 "Alveolar cells: 1909.3" "Cell type enriched" "Detected in single" 19 "choroid plexus epithelial cell: 8.7" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 764.9;Thyroid Carcinoma (TCGA): 986.8" "Group enriched" "Detected in many" 6 "cerebellum: 5.4;choroid plexus: 15.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 53.2;ovarian cancer: 115.1;pancreatic cancer: 54.6;Uterine cancer: 52.8" "Kidney - Macrophages, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Alveolar cell types: 26757317.6" "Tissue enriched" "Detected in some" "lung: 12230182.5" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Lung - Secretion" "Cluster 5: Non-specific - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 81: Alveolar cells - Lung function" 13 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: , HPA066474: " "unprognostic (1.01e-2)" "unprognostic (5.82e-2)" "unprognostic (1.21e-1)" "unprognostic (1.64e-3)" "unprognostic (2.55e-1)" "unprognostic (5.37e-2)" "unprognostic (1.79e-1)" "unprognostic (3.23e-3)" "unprognostic (2.50e-1)" "potential prognostic favorable (1.65e-6)" "unprognostic (2.50e-2)" "unprognostic (1.22e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (6.89e-2)" "unprognostic (1.63e-3)" "unprognostic (1.05e-1)" "unprognostic (4.29e-3)" "unprognostic (1.16e-2)" "unprognostic (2.91e-2)" "unprognostic (6.27e-2)" "unprognostic (9.30e-2)" "unprognostic (1.60e-1)" "unprognostic (1.21e-1)" "unprognostic (1.61e-2)" "unprognostic (1.15e-2)" SLC35C1 "FLJ11320, FUCT1" ENSG00000181830 "Solute carrier family 35 member C1" Q96A29 11 45804072-45813016 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 92.4" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 293.6" "Cell type enriched" "Detected in many" 4 "Apical squamous epithelial cells: 293.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Skin - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Alveolar cell types: 1992584.5;Pancreas epithelial cells: 656879.9" "Tissue enriched" "Detected in some" "lymphoid tissue: 344399.9" HPA064001 Enhanced Supported "Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 84: Apical squamous epithelium - Cornification" 5 "Golgi apparatus" "HPA064001: " "unprognostic (4.98e-2)" "potential prognostic unfavorable (3.55e-4)" "unprognostic (2.41e-1)" "unprognostic (4.68e-3)" "unprognostic (1.24e-1)" "unprognostic (2.39e-2)" "unprognostic (3.29e-2)" "potential prognostic unfavorable (3.99e-4)" "unprognostic (1.10e-1)" "unprognostic (1.59e-2)" "potential prognostic favorable (1.82e-4)" "unprognostic (1.61e-2)" "unprognostic (8.00e-3)" "unprognostic (2.89e-2)" "unprognostic (3.42e-2)" "unprognostic (1.51e-2)" "unprognostic (1.63e-3)" "unprognostic (7.17e-3)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (2.09e-1)" "unprognostic (1.73e-2)" "unprognostic (1.56e-1)" "unprognostic (1.41e-1)" "unprognostic (1.43e-1)" "unprognostic (3.16e-3)" "unprognostic (4.10e-1)" "unprognostic (2.41e-2)" "unprognostic (8.84e-2)" "unprognostic (3.52e-2)" "unprognostic (2.77e-2)" SLC35C2 "bA394O2.1, C20orf5, CGI-15, OVCOV1" ENSG00000080189 "Solute carrier family 35 member C2" Q9NQQ7 20 46345980-46364458 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 144.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1390944.4;Pancreas epithelial cells: 1011451.4;Pancreatic islets: 1211425.8" "Group enriched" "Detected in some" "bone marrow: 376863.1;lymphoid tissue: 168721.7" HPA027011 Approved Supported "Nucleoplasm,Golgi apparatus" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 19: Astrocytes - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 6 "Golgi apparatus" Nucleoplasm "HPA027011: " "unprognostic (1.97e-2)" "potential prognostic unfavorable (6.26e-4)" "unprognostic (2.26e-1)" "unprognostic (1.91e-2)" "unprognostic (9.55e-2)" "unprognostic (1.34e-1)" "unprognostic (2.86e-3)" "unprognostic (4.39e-1)" "unprognostic (7.12e-2)" "unprognostic (1.64e-1)" "potential prognostic unfavorable (7.39e-5)" "unprognostic (1.34e-2)" "unprognostic (1.04e-2)" "validated prognostic unfavorable (3.75e-5)" "validated prognostic unfavorable (2.66e-4)" "unprognostic (9.66e-2)" "unprognostic (1.07e-1)" "unprognostic (4.01e-2)" "unprognostic (8.60e-2)" "unprognostic (5.28e-2)" "unprognostic (6.60e-2)" "unprognostic (1.36e-1)" "unprognostic (1.06e-1)" "unprognostic (3.39e-1)" "unprognostic (7.31e-3)" "unprognostic (2.54e-2)" "unprognostic (3.94e-1)" "unprognostic (1.60e-1)" "unprognostic (3.46e-1)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" SLC35F3 FLJ37712 ENSG00000183780 "Solute carrier family 35 member F3" Q8IY50 1 233904676-234324511 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 15.5" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 297.8;Brain excitatory neurons: 450.7;Brain inhibitory neurons: 1145.0;Oligodendrocyte progenitor cells: 362.3;Other brain neurons: 345.3;Pancreatic islet cells: 552.9;pDCs: 237.5;Renal collecting duct intercalated cells: 225.4;Respiratory ionocytes: 287.0;Retinal amacrine cells: 183.1;Somatotrophs: 187.2" "Cell type enhanced" "Detected in many" "Glial cells: 362.3;Neuronal cells: 1145.0;Pancreatic islet cells: 552.9" "Cell type enhanced" "Detected in all" "medium spiny neuron: 2781.8" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 5.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 35 "plasmacytoid DC: 3.5" "Lineage enriched" "Detected in single" 35 "dendritic cells: 3.5" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells, Kidney - Intercalated cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2713 "cerebral cortex: 271337.5" "HPA051327, HPA061582" Uncertain Approved "Nucleoli,Golgi apparatus" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Golgi apparatus" Nucleoli "HPA051327: , HPA061582: " "unprognostic (3.68e-2)" "unprognostic (1.06e-1)" "unprognostic (9.67e-2)" "unprognostic (2.05e-1)" "unprognostic (5.12e-2)" "unprognostic (7.80e-3)" "unprognostic (4.85e-3)" "unprognostic (2.85e-2)" "unprognostic (3.71e-1)" "unprognostic (3.50e-2)" "unprognostic (5.98e-2)" "unprognostic (3.13e-1)" "unprognostic (3.52e-2)" "potential prognostic unfavorable (2.82e-4)" "unprognostic (2.67e-1)" "unprognostic (3.64e-1)" SLC38A5 "JM24, SN2" ENSG00000017483 "Solute carrier family 38 member 5" Q8WUX1 X 48458537-48470260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 223.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 33.7;Enteric stem cells: 27.3;Epididymal basal cells: 32.2;Erythrocyte progenitors: 95.7;Erythrocytes: 38.7;Esophageal basal cells: 32.7;Gastric chief cells: 44.8;Pancreatic acinar cells: 121.0;Plasma cells: 71.3" "Cell type enhanced" "Detected in many" "Acinar cells: 121.0;Erythrocytes: 95.7;Plasma cells: 71.3" "Cell type enriched" "Detected in some" 18 "endothelial cell: 334.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Myeloma: 246.7" "Prostate - Fibroblasts, Stomach - Chief cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39576 "Pancreas epithelial cells: 4993217.9;Pancreatic islets: 2922017.8" "Group enriched" "Detected in some" 401686 "pancreas: 35955527.9;Stomach: 44381588.8" HPA047411 Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 8: Pancreas - Proteolysis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 104: Brain endothelial cells - Blood brain barrier" 9 "Vesicles, Plasma membrane" Cytosol "HPA047411: " "unprognostic (1.27e-1)" "unprognostic (8.01e-2)" "unprognostic (2.25e-1)" "unprognostic (9.54e-3)" "unprognostic (3.64e-2)" "unprognostic (3.50e-3)" "potential prognostic favorable (4.92e-4)" "unprognostic (1.05e-1)" "unprognostic (2.21e-1)" "validated prognostic unfavorable (1.46e-8)" "validated prognostic unfavorable (3.10e-6)" "unprognostic (2.61e-2)" "unprognostic (9.06e-3)" "unprognostic (1.19e-1)" "unprognostic (8.11e-3)" "unprognostic (9.16e-2)" "unprognostic (1.53e-1)" "unprognostic (3.33e-1)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (7.10e-4)" "unprognostic (6.43e-2)" "unprognostic (2.17e-2)" "unprognostic (3.39e-3)" "unprognostic (1.20e-1)" "unprognostic (3.28e-1)" "unprognostic (3.14e-3)" "unprognostic (2.21e-1)" "unprognostic (1.65e-1)" "unprognostic (1.70e-2)" SLC39A5 ENSG00000139540 "Solute carrier family 39 member 5" Q6ZMH5 12 56230049-56237846 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 32 "intestine: 223.1;kidney: 102.5;liver: 165.6;pancreas: 291.7" "Cell type enriched" "Detected in some" 4 "Enterocytes: 744.8" "Cell type enriched" "Detected in many" 4 "Enterocytes: 744.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 64.0" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "colorectal cancer: 20.4;Gastric cancer: 12.0;liver cancer: 22.1" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Region enhanced" "Detected in single" "basal ganglia: 1.1" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Hepatocytes: 558573.7;Pancreas epithelial cells: 1196605.8" "Tissue enriched" "Detected in some" "liver: 2545347.6" HPA018423 Approved Nucleoplasm,Vesicles NA NA "Cluster 60: Stomach - Digestion" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 13 Vesicles Nucleoplasm "HPA018423: " "unprognostic (1.41e-2)" "unprognostic (9.70e-2)" "unprognostic (2.65e-1)" "potential prognostic favorable (3.66e-9)" "unprognostic (3.93e-3)" "unprognostic (1.95e-2)" "unprognostic (1.45e-1)" "unprognostic (2.65e-2)" "unprognostic (1.90e-1)" "unprognostic (7.88e-2)" "unprognostic (3.91e-2)" "unprognostic (2.57e-2)" "unprognostic (6.93e-2)" "unprognostic (4.73e-1)" "unprognostic (2.92e-1)" "unprognostic (2.28e-1)" SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 400.9;Retinal pigment epithelial cells: 443.3;Syncytiotrophoblasts: 1124.0" "Cell type enhanced" "Detected in all" "Trophoblast cells: 1124.0" "Cell type enhanced" "Detected in all" "endothelial cell: 215.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Proximal tubular cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 105299660.3;Glomeruli: 132686041.1;Microglia and Neuropil: 132512996.1;Pancreatic islets: 147349898.6;Proximal tubules: 323764615.2" "Tissue enriched" "Detected in all" "cerebral cortex: 191595382.1" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 61000000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 58 "Nucleoplasm, Plasma membrane" "CAB010455: , HPA017980: " "unprognostic (2.19e-2)" "unprognostic (5.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.51e-1)" "unprognostic (8.33e-2)" "unprognostic (3.01e-2)" "unprognostic (5.63e-2)" "unprognostic (1.12e-1)" "unprognostic (1.49e-3)" "unprognostic (2.57e-1)" "unprognostic (1.14e-3)" "unprognostic (5.59e-2)" "unprognostic (1.40e-1)" "unprognostic (1.45e-2)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (7.08e-5)" "unprognostic (1.61e-2)" "unprognostic (4.15e-1)" "unprognostic (2.73e-1)" "unprognostic (7.89e-2)" "unprognostic (6.26e-2)" "unprognostic (5.35e-2)" "unprognostic (1.10e-2)" "unprognostic (1.61e-1)" "unprognostic (2.71e-1)" "unprognostic (2.46e-2)" "unprognostic (2.71e-1)" "unprognostic (6.16e-2)" "unprognostic (5.98e-2)" "unprognostic (1.49e-1)" "unprognostic (1.74e-2)" SLC51B OSTbeta ENSG00000186198 "Solute carrier family 51 subunit beta" Q86UW2 15 65045387-65053397 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 39.4;intestine: 100.8" "Group enriched" "Detected in many" 4 "Colonocytes: 335.8;Enterocytes: 679.6;Epididymal efferent duct absorptive cells: 241.3" "Group enriched" "Detected in many" 5 "Ductal cells: 241.3;Enterocytes: 679.6" "Group enriched" "Detected in some" 4 "astrocyte: 6.1;ependymal cell: 6.3;pericyte: 4.3;vascular associated smooth muscle cell: 7.9" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "liver cancer: 12.7" "Adipose subcutaneous - Smooth muscle cells, Colon - Colon enterocytes, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5461 "Proximal tubules: 546146.7" "Tissue enriched" "Detected in single" 9006 "kidney: 900583.1" "HPA008398, HPA008533" Enhanced Approved Vesicles,Mitochondria No NA "Cluster 77: Intestine - Digestion" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 4 Mitochondria Vesicles "HPA008398: , HPA008533: " "unprognostic (5.73e-2)" "unprognostic (5.07e-2)" "unprognostic (6.60e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (8.40e-7)" "unprognostic (1.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.29e-3)" "potential prognostic favorable (5.87e-4)" "unprognostic (2.11e-1)" "unprognostic (8.17e-3)" "unprognostic (3.66e-2)" "unprognostic (2.69e-1)" "unprognostic (5.06e-3)" "unprognostic (1.08e-1)" "unprognostic (8.15e-2)" "unprognostic (9.33e-2)" "unprognostic (8.15e-3)" SLC5A1 "D22S675, NAGT, SGLT1" ENSG00000100170 "Solute carrier family 5 member 1" P13866 22 32043261-32113029 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Sugar transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "intestine: 497.5" "Cell type enriched" "Detected in many" 8 "Enterocytes: 1403.9" "Cell type enriched" "Detected in many" 8 "Enterocytes: 1403.9" "Low cell type specificity" "Detected in some" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 30.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Bile duct cancer: 3.3;colorectal cancer: 8.3;Gastric cancer: 2.7" "Colon - Colon enterocytes, Heart muscle - Cardiomyocytes, Kidney - Ascending Loop of Henle cells, Liver - Cholangiocytes, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in single" 26 "cerebellum: 7.6" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Proximal tubules: 36783579.0" "Tissue enriched" "Detected in some" "intestine: 119911200.6" "CAB015467, HPA051805, HPA055106" Enhanced Approved "Nuclear membrane,Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Small intestine - Absorption and Digestion" "Cluster 9: Non-specific - Receptor signaling" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 1: Enterocytes - Absorption and Digestion" 1 "Golgi apparatus, Plasma membrane" "Nuclear membrane" "CAB015467: , HPA051805: , HPA055106: " "unprognostic (5.41e-2)" "unprognostic (1.39e-1)" "unprognostic (1.57e-1)" "unprognostic (7.52e-2)" "unprognostic (5.85e-2)" "unprognostic (5.91e-2)" "unprognostic (2.96e-1)" "validated prognostic favorable (4.06e-9)" "validated prognostic favorable (4.70e-4)" "potential prognostic favorable (1.39e-4)" "unprognostic (1.61e-2)" "unprognostic (6.50e-2)" "unprognostic (5.70e-3)" "unprognostic (3.20e-3)" "unprognostic (1.36e-1)" "unprognostic (1.53e-1)" "unprognostic (1.45e-1)" "unprognostic (5.68e-2)" "unprognostic (6.23e-2)" "unprognostic (1.15e-1)" "unprognostic (9.00e-3)" "unprognostic (1.10e-1)" "unprognostic (2.61e-3)" "unprognostic (2.22e-3)" SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 45.1;intestine: 28.2;kidney: 160.2" "Cell type enhanced" "Detected in some" "Enterocytes: 377.7;Epididymal principal cells: 223.1;Proximal tubule cells: 1239.1" "Cell type enhanced" "Detected in many" "Enterocytes: 377.7;Renal nephron cells: 1239.1;Reproductive supporting cells: 223.1" "Cell type enhanced" "Detected in some" "astrocyte: 6.4;committed oligodendrocyte precursor: 5.8" "Cancer enriched" "Detected in some" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 19.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "testis cancer: 3.0" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" "Glomeruli: 64451079.0;Proximal tubules: 72326963.3" "Tissue enriched" "Detected in some" "kidney: 2179009.6" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Plasma membrane" Nucleoplasm "HPA060904: " "unprognostic (6.79e-2)" "unprognostic (3.11e-2)" "validated prognostic favorable (1.88e-8)" "validated prognostic favorable (2.35e-4)" "unprognostic (5.04e-2)" "unprognostic (1.07e-2)" "unprognostic (2.39e-1)" SLC5A6 SMVT ENSG00000138074 "Solute carrier family 5 member 6" Q9Y289 2 27199587-27212958 "Disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 96.2" "Cell type enhanced" "Detected in many" "Breast secretory cells: 78.2;Cardiomyocytes: 71.0;Cytotrophoblasts: 133.6;Epididymal principal cells: 104.5;Extravillous trophoblasts: 121.8;Migrating cytotrophoblasts: 172.5;Syncytiotrophoblasts: 302.3" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 104.5;Trophoblast cells: 302.3" "Group enriched" "Detected in all" 6 "choroid plexus epithelial cell: 40.1;endothelial cell: 102.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 443684.5;Proximal tubules: 218634.5" "Not detected" "Not detected" HPA036958 Approved Approved "Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 34: Testis cancer - Unknown function" "Cluster 13: Syncytiotrophoblasts - Placental remodeling & endocrine func." 10 "Plasma membrane" "HPA036958: " "unprognostic (1.53e-2)" "unprognostic (1.07e-1)" "unprognostic (1.50e-1)" "unprognostic (1.17e-3)" "unprognostic (1.95e-1)" "unprognostic (7.16e-3)" "unprognostic (2.87e-1)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (8.12e-2)" "unprognostic (9.97e-3)" "potential prognostic unfavorable (6.30e-4)" "unprognostic (1.12e-2)" "unprognostic (1.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.43e-3)" "unprognostic (5.49e-3)" "unprognostic (1.77e-1)" "unprognostic (2.79e-2)" "unprognostic (2.27e-1)" "unprognostic (2.73e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (7.91e-2)" "unprognostic (3.50e-2)" "unprognostic (1.17e-1)" "unprognostic (1.36e-1)" "unprognostic (1.95e-3)" "unprognostic (1.75e-2)" "unprognostic (3.92e-3)" "unprognostic (8.11e-2)" SLC6A11 GAT3 ENSG00000132164 "Solute carrier family 6 member 11" P48066 3 10816201-10940714 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 77.7" "Cell type enhanced" "Detected in some" "Astrocytes: 300.3;Brain inhibitory neurons: 53.2;Ependymal cells: 37.7;Esophageal suprabasal cells: 34.8;Extravillous trophoblasts: 43.8;Leydig cells: 33.5;Müller glia: 53.3;Oligodendrocyte progenitor cells: 30.9;Peritubular myoid cells: 43.5;Retinal amacrine cells: 121.1" "Group enriched" "Detected in many" 4 "Glial cells: 300.3;Neuronal cells: 121.1" "Group enriched" "Detected in all" 6 "astrocyte: 449.0;midbrain-derived inhibitory: 299.0" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 7.2" "Prostate - Prostate glandular cells, Skin - Keratinocyte (other), Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27949 "Astrocytes and Neuropil: 3217681.9;Microglia and Neuropil: 4004882.7;Neurons: 1162069.8" "Tissue enriched" "Detected in single" 41039 "cerebral cortex: 4103866.2" HPA037981 Supported Supported Uncertain Nucleoplasm,Vesicles NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 28: Astrocytes - Homeostasis & neuron support" Nucleoplasm Vesicles "HPA037981: " "unprognostic (3.04e-1)" "unprognostic (2.55e-1)" "unprognostic (3.55e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (4.38e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (8.58e-2)" "unprognostic (4.57e-2)" "unprognostic (1.13e-1)" "unprognostic (9.24e-2)" "unprognostic (1.60e-1)" "unprognostic (1.48e-2)" "unprognostic (3.63e-2)" "unprognostic (3.83e-2)" SLC6A13 GAT2 ENSG00000010379 "Solute carrier family 6 member 13" Q9NSD5 12 220621-262873 "Metabolic proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "kidney: 142.8;liver: 36.8" "Group enriched" "Detected in some" 14 "Proximal tubule cells: 421.7;Retinal pigment epithelial cells: 733.2" "Group enriched" "Detected in many" 14 "Pigment cells: 733.2;Renal nephron cells: 421.7" "Group enriched" "Detected in many" 31 "fibroblast: 408.5;pericyte: 665.0" "Group enriched" "Detected in many" 16 "Kidney Renal Clear Cell Carcinoma (TCGA): 135.1;Kidney Renal Papillary Cell Carcinoma (TCGA): 88.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 2.3" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 18985 "Glomeruli: 1010880.5;Proximal tubules: 2786042.1" "Tissue enriched" "Detected in single" 789 "kidney: 78850.5" "HPA036449, HPA052726" Supported Nucleoplasm,Nucleoli,Mitochondria,Cytosol NA NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 38: Sub-cortical - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 88: Proximal tubular cells - Transmembrane transport" Mitochondria "Nucleoplasm, Nucleoli, Cytosol" "HPA036449: , HPA052726: " "unprognostic (3.49e-1)" "unprognostic (2.37e-1)" "unprognostic (1.29e-2)" "validated prognostic favorable (4.65e-8)" "validated prognostic favorable (3.80e-4)" "potential prognostic favorable (6.58e-5)" "unprognostic (3.89e-2)" "unprognostic (2.53e-3)" "unprognostic (1.60e-1)" "unprognostic (1.82e-1)" "unprognostic (2.85e-1)" "unprognostic (2.52e-2)" "unprognostic (3.24e-3)" SLC6A14 ENSG00000268104 "Solute carrier family 6 member 14" Q9UN76 X 116436606-116461458 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" Obesity "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 15.1;salivary gland: 20.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 470.2;Breast secretory cells: 74.6;Conjunctival goblet cells: 91.3;Endometrial secretory cells: 72.0;Lacrimal acinar cells: 74.3;Respiratory basal cells: 114.9;Respiratory deuterosomal cells: 136.8;Respiratory secretory cells: 228.2;Salivary acinar cells: 320.3;Salivary myoepithelial cells: 68.2;Transitional alveolar cells: 159.2" "Cell type enhanced" "Detected in many" "Acinar cells: 320.3;Alveolar cells: 470.2;Ciliated cells: 136.8;Secretory cells: 228.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Lung Adenocarcinoma (TCGA): 28.3" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 10.1" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells" "Cell type enriched" "Detected in single" 94 "Alveolar cell types: 9412.7" "Tissue enriched" "Detected in some" "lung: 1699505.3" HPA003193 Uncertain Approved "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Mitochondria" NA NA "Cluster 82: Salivary gland - Secretion" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" "Vesicles, Primary cilium, Primary cilium tip" "Plasma membrane, Mitochondria" "HPA003193: " "unprognostic (1.03e-1)" "unprognostic (6.33e-2)" "unprognostic (1.97e-1)" "unprognostic (1.30e-2)" "unprognostic (1.66e-1)" "unprognostic (1.29e-1)" "unprognostic (1.66e-2)" "unprognostic (3.02e-2)" "unprognostic (1.12e-3)" "unprognostic (2.32e-1)" "unprognostic (3.57e-3)" "unprognostic (2.20e-1)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (5.67e-2)" "unprognostic (4.59e-1)" "unprognostic (1.21e-1)" "unprognostic (2.93e-1)" "unprognostic (1.89e-2)" "unprognostic (2.12e-1)" "unprognostic (4.89e-2)" SLC6A2 "NAT1, NET, NET1, SLC6A5" ENSG00000103546 "Solute carrier family 6 member 2" P23975 16 55655988-55707645 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.9;placenta: 6.4;skin 1: 4.4;testis: 4.2" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 31.9;Epididymal efferent duct absorptive cells: 50.6;Epididymal efferent duct ciliated cells: 7.1;Extravillous trophoblasts: 19.9;Late primary spermatocytes: 16.2;Late spermatids: 9.0;Podocytes: 8.5;Syncytiotrophoblasts: 9.8" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 31.9;Ductal cells: 50.6;Spermatogenic cell types: 16.2;Trophoblast cells: 19.9" "Cell type enriched" "Detected in single" 4 "CGE interneuron: 3.5" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 6.2" "Region enriched" "Detected in some" 35 "pons: 192.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 50 "Neuroblastoma: 54.0" "Adrenal gland - Adrenal medulla cells, Minor Salivary Gland - Fibroblasts, Testis - Early spermatids" "Region enriched" "Detected in some" 4 "pons and medulla: 7.8" "Region enriched" "Detected in single" 19 "pons: 17.9" "Group enriched" "Detected in some" 2510 "Capillaries: 314491.7;Large ducts: 187497.6" "Tissue enriched" "Detected in some" "fallopian tube: 196442.6" "HPA004057, HPA076311, CAB078195" Enhanced Supported Approved Mitochondria,Cytosol NA NA "Cluster 43: Placenta - Pregnancy hormone signaling" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 2 Cytosol Mitochondria "CAB078195: , HPA004057: , HPA076311: " "unprognostic (6.90e-2)" "unprognostic (9.28e-2)" "unprognostic (3.02e-1)" "unprognostic (4.14e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-1)" "unprognostic (1.57e-1)" "unprognostic (1.36e-2)" "unprognostic (1.63e-2)" SLC9A3 "NHE-3, NHE3" ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "gallbladder: 42.6;intestine: 88.4;kidney: 64.4;stomach 1: 47.2" "Group enriched" "Detected in some" 4 "Epicardial cells: 50.0;Loop of henle epithelial cells: 135.2;Proximal tubule cells: 67.4" "Group enriched" "Detected in many" 4 "Barrier epithelial cells: 50.0;Renal nephron cells: 135.2" "Cell type enhanced" "Detected in some" "mammillary body: 4.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 23822 "Distal tubules: 2516200.4;Proximal tubules: 2248194.9" "Group enriched" "Detected in some" 62 "intestine: 5009.1;Stomach: 7486.6" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 37: Neurons - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 7 "Plasma membrane" "HPA036493: , HPA036669: " "unprognostic (2.49e-2)" "unprognostic (2.24e-2)" "unprognostic (8.23e-2)" "unprognostic (3.71e-1)" "unprognostic (2.05e-1)" "unprognostic (9.80e-2)" "unprognostic (3.33e-1)" "unprognostic (1.06e-3)" "unprognostic (2.15e-2)" "unprognostic (1.32e-2)" "unprognostic (1.77e-2)" "unprognostic (7.25e-2)" "potential prognostic favorable (7.69e-4)" "unprognostic (2.50e-2)" "unprognostic (4.05e-2)" "unprognostic (1.40e-1)" "unprognostic (4.69e-2)" "unprognostic (1.45e-1)" "unprognostic (1.14e-2)" "unprognostic (2.60e-3)" "unprognostic (2.51e-1)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (6.95e-2)" "unprognostic (1.07e-1)" "unprognostic (4.75e-1)" "unprognostic (5.21e-2)" "unprognostic (7.49e-2)" SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant, Osteoporosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 348.1" "Cell type enhanced" "Detected in many" "Enterocytes: 508.6;Esophageal apical cells: 681.6;Esophageal suprabasal cells: 576.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 681.6;Enterocytes: 508.6;Suprabasal cells: 576.3" "Cell type enhanced" "Detected in many" "astrocyte: 55.5;leukocyte: 75.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 462.6" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate glandular cells, Spleen - T-cells, Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Glomeruli: 373108284.5;Proximal tubules: 514091562.6" "Tissue enriched" "Detected in all" "kidney: 1553931402.4" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite,Centrosome,Basal body,Cytosol,Calyx" NA Yes 3700000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 27: Breast cancer - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 64 "Plasma membrane, Centriolar satellite" "Vesicles, Centrosome, Basal body, Cytosol, Calyx" "CAB001962: , HPA009672: , HPA027247: " "unprognostic (3.28e-2)" "unprognostic (7.70e-2)" "unprognostic (1.89e-1)" "unprognostic (2.86e-1)" "unprognostic (2.99e-2)" "unprognostic (4.92e-2)" "unprognostic (1.96e-2)" "unprognostic (8.46e-2)" "unprognostic (2.00e-1)" "unprognostic (2.27e-1)" "potential prognostic favorable (5.98e-4)" "unprognostic (3.87e-1)" "unprognostic (2.88e-3)" "validated prognostic unfavorable (4.49e-6)" "validated prognostic unfavorable (1.30e-8)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (1.32e-2)" "unprognostic (1.15e-1)" "unprognostic (8.18e-2)" "unprognostic (1.17e-1)" "unprognostic (4.21e-2)" "unprognostic (1.92e-1)" "unprognostic (1.04e-1)" "unprognostic (1.27e-2)" "unprognostic (1.12e-1)" "unprognostic (5.67e-2)" "unprognostic (6.41e-2)" "unprognostic (5.31e-2)" "unprognostic (2.69e-1)" "unprognostic (3.46e-3)" SLCO1A2 "OATP, OATP-A, OATP1A2, SLC21A3" ENSG00000084453 "Solute carrier organic anion transporter family member 1A2" P46721 12 21264600-21419594 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 15.0;choroid plexus: 7.0;liver: 7.5;salivary gland: 14.6" "Group enriched" "Detected in some" 8 "Oligodendrocytes: 530.1;Retinal pigment epithelial cells: 225.9" "Group enriched" "Detected in many" 10 "Glial cells: 530.1;Pigment cells: 225.9" "Group enriched" "Detected in many" 4 "endothelial cell: 830.6;oligodendrocyte: 712.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 25.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 14870.0;Hepatocytes: 6546.8" "Not detected" "Not detected" HPA071152 Supported "Plasma membrane" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 104: Brain endothelial cells - Blood brain barrier" "Plasma membrane" "HPA071152: " "unprognostic (3.27e-1)" "unprognostic (3.32e-3)" "unprognostic (6.03e-2)" "unprognostic (6.78e-2)" "unprognostic (4.54e-2)" "potential prognostic favorable (5.43e-4)" "unprognostic (5.50e-2)" "unprognostic (3.28e-2)" "unprognostic (5.09e-2)" "unprognostic (9.29e-2)" "unprognostic (1.31e-2)" "unprognostic (2.64e-3)" "unprognostic (1.62e-2)" "unprognostic (6.77e-2)" "unprognostic (3.19e-2)" "unprognostic (3.67e-1)" "unprognostic (8.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.78e-2)" "unprognostic (2.11e-1)" "unprognostic (8.76e-2)" "unprognostic (2.70e-1)" "unprognostic (1.62e-1)" "unprognostic (4.51e-3)" "unprognostic (2.08e-1)" "unprognostic (3.61e-1)" SLCO1B3 "OATP1B3, OATP8, SLC21A8" ENSG00000111700 "Solute carrier organic anion transporter family member 1B3" Q9NPD5 12 20810702-20916911 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "liver: 247.7" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 66.3" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 66.3" "Cell type enriched" "Detected in single" 24 "choroid plexus epithelial cell: 12.4" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 19.0" "Region enriched" "Detected in some" 30 "choroid plexus: 34.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 53.7" "Liver - Hepatocytes, Minor Salivary Gland - Minor salivary gland ductal cells" "Cell type enriched" "Detected in single" 120402 "Hepatocytes: 12040164.1" "Tissue enriched" "Detected in single" 95809 "liver: 9580879.5" "HPA004943, HPA050892" Enhanced Supported "Plasma membrane" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 36: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 93: Hepatocytes - Bile production & excretion" 3 "Plasma membrane" "HPA004943: , HPA050892: " "unprognostic (7.86e-2)" "unprognostic (9.05e-2)" "unprognostic (1.27e-1)" "unprognostic (5.82e-3)" "unprognostic (2.56e-3)" "unprognostic (2.10e-2)" "potential prognostic favorable (3.79e-4)" "unprognostic (2.25e-3)" "unprognostic (1.58e-1)" "unprognostic (4.28e-2)" "unprognostic (1.81e-1)" "unprognostic (2.68e-1)" "unprognostic (1.87e-2)" "unprognostic (2.57e-2)" "unprognostic (2.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.38e-2)" "unprognostic (2.43e-1)" SLCO4C1 "OATP-H, OATP4C1, OATPX, SLC21A20" ENSG00000173930 "Solute carrier organic anion transporter family member 4C1" Q6ZQN7 5 102233986-102296284 "Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 38.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 95.1;Loop of henle epithelial cells: 107.3;Monocyte progenitors: 65.0;Neutrophil progenitors: 285.9;Neutrophils: 197.7;NK-cells: 60.4;Pituitary stem cells: 41.1;Proximal tubule cells: 97.5" "Cell type enhanced" "Detected in many" "Alveolar cells: 95.1;Neutrophils: 285.9;Renal nephron cells: 107.3" "Cell type enhanced" "Detected in many" "deep-layer near-projecting: 46.6;hippocampal CA4: 34.3;leukocyte: 34.9" "Group enriched" "Detected in many" 5 "Kidney Renal Clear Cell Carcinoma (TCGA): 32.0;Kidney Renal Papillary Cell Carcinoma (TCGA): 71.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.5;neutrophil: 9.8" "Group enriched" "Detected in many" 5 "granulocytes: 9.8;NK-cells: 2.6;T-cells: 3.8" "Cancer enhanced" "Detected in some" "Kidney cancer: 7.8" "Adrenal gland - Adrenal medulla cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland ductal cells, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 4622230.7" "Tissue enriched" "Detected in single" 1626 "kidney: 162643.6" HPA058249 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 53: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 5 "Plasma membrane" "Nucleoplasm, Cytosol" "HPA058249: " "unprognostic (2.44e-1)" "unprognostic (2.32e-1)" "unprognostic (3.04e-2)" "unprognostic (1.14e-1)" "potential prognostic favorable (3.80e-8)" "unprognostic (8.69e-2)" "unprognostic (3.99e-2)" "unprognostic (5.59e-3)" "unprognostic (2.19e-1)" "unprognostic (1.83e-3)" "unprognostic (1.35e-1)" "unprognostic (2.74e-1)" "unprognostic (6.71e-2)" "unprognostic (9.44e-2)" "unprognostic (1.33e-1)" "unprognostic (3.57e-2)" SLFN11 FLJ34922 ENSG00000172716 "Schlafen family member 11" Q7Z7L1 17 35350305-35373701 "Predicted intracellular proteins" "Antiviral defense, DNA damage, Immunity" "DNA-binding, Endonuclease, Helicase, Hydrolase, Nuclease, RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast lactating cells: 75.4;Epididymal principal cells: 93.5;Hofbauer cells: 81.5;Kupffer cells: 58.4;Macrophages: 68.0;Megakaryocyte progenitors: 58.9;Megakaryocyte-Erythroid progenitors: 58.1;Monocyte progenitors: 80.2;monocytes: 101.9;pDCs: 94.9;Plasma cells: 59.4;Respiratory deuterosomal cells: 69.5;Schwann cells: 55.8;Vascular smooth muscle cells: 58.7" "Cell type enhanced" "Detected in many" "dendritic cells: 94.9;Mononuclear phagocytes: 101.9" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 44.3;endothelial cell: 78.6;fibroblast: 37.4;leukocyte: 46.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Breast - Endothelial cells, Colon - Endothelial cells, Prostate - Fibroblasts, Skin - Endothelial cells, Testis - Endothelial cells" "Cell type enriched" "Detected in some" "Alveolar cell types: 3129245.3" "Group enriched" "Detected in many" "heart muscle: 271677.7;kidney: 229922.1;liver: 205331.5" "HPA023030, HPA062062" Uncertain Supported Nucleoplasm,Cytosol No NA "Cluster 13: Non-specific - Mitochondria" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 18 Nucleoplasm Cytosol "HPA023030: , HPA062062: " "unprognostic (4.07e-2)" "unprognostic (1.54e-1)" "unprognostic (2.73e-1)" "unprognostic (1.81e-1)" "unprognostic (3.65e-2)" "unprognostic (5.09e-2)" "potential prognostic unfavorable (5.72e-4)" "unprognostic (6.55e-3)" "unprognostic (1.20e-1)" "unprognostic (3.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.64e-1)" "unprognostic (1.25e-2)" "unprognostic (4.47e-2)" "unprognostic (8.90e-2)" "unprognostic (3.94e-2)" "unprognostic (6.53e-2)" "unprognostic (2.51e-2)" "unprognostic (3.79e-2)" "unprognostic (7.18e-2)" "unprognostic (2.44e-1)" "unprognostic (2.14e-1)" "unprognostic (4.80e-2)" "unprognostic (2.26e-1)" "unprognostic (3.54e-1)" "unprognostic (1.18e-1)" "unprognostic (5.94e-2)" "unprognostic (1.23e-1)" "unprognostic (4.10e-3)" "unprognostic (3.16e-2)" "unprognostic (1.07e-1)" SLFN13 FLJ31952 ENSG00000154760 "Schlafen family member 13" Q68D06 17 35435096-35448837 "Predicted intracellular proteins" "Endonuclease, Hydrolase, Nuclease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.2;salivary gland: 30.6" "Cell type enhanced" "Detected in many" "Breast lactating cells: 141.6;Choroid plexus epithelial cells: 47.2;Endometrial ciliated cells: 88.2;Epididymal efferent duct ciliated cells: 59.6;Erythrocyte progenitors: 81.7;Fallopian tube ciliated cells: 129.3;Lacrimal acinar cells: 50.7;Neutrophil progenitors: 59.6;NK-cells: 93.6;Respiratory ciliated cells: 121.7;Salivary acinar cells: 70.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 129.3;Erythrocytes: 81.7;NK-cells: 93.6;Secretory cells: 141.6" "Group enriched" "Detected in some" 4 "choroid plexus epithelial cell: 32.1;endothelial cell: 31.5;leukocyte: 37.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 5.3" "Group enriched" "Detected in many" 4 "granulocytes: 4.5;NK-cells: 5.3" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 3266 "Fallopian tube cells: 300567.3;Large ducts: 352667.2" "Not detected" "Not detected" "HPA022532, HPA023064" Uncertain Approved "Cytokinetic bridge" Yes No "Cluster 15: NK-cells - Unknown function" "Cluster 60: Stomach - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 55: Lymphoma - Immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" "Cytokinetic bridge" "HPA022532: , HPA023064: " "unprognostic (2.94e-2)" "unprognostic (3.83e-1)" "unprognostic (5.30e-3)" "unprognostic (2.46e-2)" "unprognostic (1.97e-1)" "unprognostic (2.65e-2)" "unprognostic (3.94e-1)" "unprognostic (1.70e-1)" "unprognostic (2.72e-2)" "unprognostic (7.10e-2)" "potential prognostic favorable (1.62e-5)" "unprognostic (8.52e-2)" "unprognostic (4.15e-2)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (6.49e-5)" "unprognostic (1.14e-1)" "unprognostic (1.59e-1)" "potential prognostic unfavorable (5.57e-5)" "unprognostic (4.22e-2)" "unprognostic (1.18e-1)" "unprognostic (7.50e-2)" "unprognostic (3.59e-3)" "unprognostic (1.55e-2)" "unprognostic (1.64e-1)" "unprognostic (9.25e-2)" "unprognostic (2.61e-1)" "unprognostic (6.22e-2)" "unprognostic (1.97e-1)" "unprognostic (2.10e-2)" "unprognostic (1.23e-1)" SLIRP "C14orf156, DC50" ENSG00000119705 "SRA stem-loop interacting RNA binding protein" Q9GZT3 14 77708071-77761104 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric progenitor cells: 698.5;Hepatocytes: 876.5;Late primary spermatocytes: 950.6;Parietal cells: 878.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA020291 Approved Supported Mitochondria No Yes "Cluster 2: Dendritic cells - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 97: Non-specific - Cellular respiration" 31 Mitochondria "HPA020291: " "potential prognostic unfavorable (3.34e-5)" "unprognostic (2.03e-1)" "potential prognostic favorable (1.66e-5)" "unprognostic (2.11e-1)" "unprognostic (4.60e-2)" "unprognostic (4.03e-2)" "unprognostic (3.64e-1)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (7.36e-2)" "unprognostic (6.02e-2)" "unprognostic (3.27e-1)" "unprognostic (2.29e-2)" "unprognostic (2.07e-3)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (1.96e-1)" "unprognostic (1.66e-2)" "unprognostic (1.52e-2)" "unprognostic (3.80e-3)" "unprognostic (9.15e-2)" "unprognostic (6.59e-2)" "unprognostic (9.51e-2)" "unprognostic (1.55e-1)" "unprognostic (1.06e-1)" "unprognostic (2.50e-1)" "unprognostic (1.24e-1)" "unprognostic (2.14e-1)" "unprognostic (3.09e-1)" "unprognostic (4.27e-2)" "unprognostic (2.85e-1)" SLITRK3 KIAA0848 ENSG00000121871 "SLIT and NTRK like family member 3" O94933 3 165186720-165197109 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.3;fallopian tube: 13.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 16.7;Brain inhibitory neurons: 19.9;Oligodendrocyte progenitor cells: 36.3;Other brain neurons: 15.0;Retinal amacrine cells: 4.8;Retinal bipolar cells: 14.3;Smooth muscle cells: 10.7" "Group enriched" "Detected in some" 10 "Glial cells: 36.3;Neuronal cells: 19.9;Smooth muscle cells: 10.7" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 25 "Glioblastoma Multiforme (TCGA): 12.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 10.6;prostate cancer: 2.8" "Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 501 "Astrocytes and Neuropil: 38312.8;Microglia and Neuropil: 62763.2;Neurons: 49189.6" "Group enriched" "Detected in some" 475 "cerebral cortex: 27476.3;fallopian tube: 67523.4" "HPA017636, HPA048042" Enhanced Approved Mitochondria No NA 450000 "Cluster 65: Brain - Transcription" "Cluster 29: Forebrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 Mitochondria "HPA017636: , HPA048042: " "unprognostic (1.48e-1)" "unprognostic (1.38e-1)" SLITRK5 "bA364G4.2, KIAA0918, LRRC11" ENSG00000165300 "SLIT and NTRK like family member 5" O94991 13 87671371-87696272 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.2;fallopian tube: 9.6;salivary gland: 9.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 95.9;Brain inhibitory neurons: 80.7;Ependymal cells: 31.0;Fallopian secretory cells: 22.0;Lacrimal acinar cells: 75.2;Oligodendrocyte progenitor cells: 84.0;Other brain neurons: 51.9;Pituitary stem cells: 32.5;Salivary acinar cells: 47.2;Schwann cells: 24.0" "Cell type enhanced" "Detected in many" "Acinar cells: 75.2;Glial cells: 84.0;Neuronal cells: 95.9" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 3928 "Fallopian tube cells: 436117.8;Microglia and Neuropil: 317578.5;Neurons: 424789.1" "Group enriched" "Detected in some" 17415 "cerebral cortex: 2192944.5;fallopian tube: 1290046.6" "HPA013843, HPA073230" Uncertain Approved Vesicles NA NA "Cluster 65: Brain - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "HPA013843: , HPA073230: " "unprognostic (3.01e-1)" "potential prognostic favorable (2.07e-5)" "unprognostic (4.54e-1)" SLPI "ALK1, ALP, BLPI, HUSI, HUSI-I, WAP4, WFDC4" ENSG00000124107 "Secretory leukocyte peptidase inhibitor" P03973 20 45252239-45254564 "Cancer-related genes, Plasma proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial, Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "cervix: 26260.0;salivary gland: 14071.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 7287.2;Conjunctival goblet cells: 12808.6;Endometrial secretory cells: 16781.7;Esophageal apical cells: 20421.8;Lacrimal acinar cells: 10826.4;Respiratory deuterosomal cells: 12518.3;Respiratory secretory cells: 25615.0;Salivary acinar cells: 11099.1;Salivary duct cells: 7577.7;Submucosal glandular cells: 31818.4;Transitional alveolar cells: 11204.8" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 20421.8;Ciliated cells: 12518.3;Glandular cells: 31818.4;Goblet cells: 12808.6;Secretory cells: 25615.0" "Group enriched" "Detected in some" 5 "endothelial cell: 10.0;fibroblast: 38.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 7 "choroid plexus: 50.1;thalamus: 14.3" "Immune cell enriched" "Detected in some" 80 "neutrophil: 323.6" "Lineage enriched" "Detected in many" 80 "granulocytes: 323.6" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 652.3" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002303, HPA027774" Enhanced Approved "Golgi apparatus" "Secreted to blood" Immunity NA NA 26400000 20000000 "Cluster 4: Neutrophils - Degranulation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 15: Kidney cancer - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 13 "Golgi apparatus" "CAB002303: , HPA027774: " "unprognostic (2.48e-1)" "unprognostic (5.30e-2)" "unprognostic (1.13e-1)" "unprognostic (4.37e-1)" "unprognostic (2.05e-1)" "unprognostic (4.64e-2)" "unprognostic (3.30e-2)" "potential prognostic unfavorable (9.64e-4)" "unprognostic (4.20e-2)" "unprognostic (3.67e-1)" "potential prognostic unfavorable (4.04e-9)" "unprognostic (7.35e-2)" "unprognostic (9.86e-2)" "unprognostic (1.32e-1)" "unprognostic (1.09e-2)" "unprognostic (2.65e-1)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (5.16e-3)" "validated prognostic unfavorable (1.99e-4)" "validated prognostic unfavorable (1.46e-4)" "unprognostic (2.17e-2)" "unprognostic (9.43e-2)" "unprognostic (1.29e-2)" "unprognostic (1.06e-1)" "unprognostic (2.74e-2)" "unprognostic (2.42e-1)" "unprognostic (1.81e-1)" "unprognostic (1.87e-1)" "unprognostic (7.72e-2)" "unprognostic (1.16e-1)" SMAD2 "JV18-1, MADH2, MADR2" ENSG00000175387 "SMAD family member 2" Q15796 18 47808957-47931146 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 3612405.0" "Tissue enhanced" "Detected in many" "intestine: 53644951.8" "CAB025507, HPA067203, CAB073546" Approved Supported "Nucleoplasm,Nucleoli,Vesicles,Primary cilium transition zone,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" 109 "Nucleoplasm, Nucleoli" "Vesicles, Primary cilium transition zone, Cytosol" "CAB025507: , CAB073546: , HPA067203: " "unprognostic (9.69e-3)" "unprognostic (5.71e-2)" "unprognostic (7.85e-2)" "unprognostic (2.17e-2)" "unprognostic (5.87e-2)" "unprognostic (2.31e-2)" "unprognostic (1.49e-1)" "unprognostic (2.72e-2)" "unprognostic (2.01e-1)" "potential prognostic unfavorable (9.99e-4)" "potential prognostic favorable (6.97e-8)" "unprognostic (1.13e-3)" "unprognostic (2.14e-1)" "validated prognostic unfavorable (1.28e-4)" "validated prognostic unfavorable (2.25e-4)" "unprognostic (6.03e-3)" "unprognostic (1.76e-2)" "unprognostic (9.65e-2)" "unprognostic (1.84e-2)" "unprognostic (3.71e-2)" "unprognostic (2.24e-2)" "unprognostic (1.71e-3)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "unprognostic (1.17e-1)" "unprognostic (1.05e-1)" "unprognostic (1.43e-2)" "unprognostic (1.01e-1)" "unprognostic (3.38e-1)" "unprognostic (2.33e-2)" "unprognostic (4.99e-2)" SMAD3 "HsT17436, JV15-2, MADH3" ENSG00000166949 "SMAD family member 3" P84022 15 67063763-67195173 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Aortic aneurysm, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 778.2;Myonuclei: 586.8;Ocular epithelial cells: 585.8;Urothelial cells: 1009.9" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 1009.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 21305037.4" "Tissue enhanced" "Detected in many" "pancreas: 1977138.2" "CAB008094, HPA046386, HPA067203, CAB069409" Approved Supported "Nucleoplasm,Vesicles,Primary cilium transition zone,Basal body" NA Yes "Cluster 3: Non-specific - Nuclear processes" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 51: Secretory epithelial cells - Mixed function" 210 Nucleoplasm "Vesicles, Primary cilium transition zone, Basal body" "CAB008094: , CAB069409: , HPA046386: , HPA067203: " "unprognostic (6.56e-2)" "unprognostic (1.48e-1)" "unprognostic (8.19e-2)" "unprognostic (1.27e-2)" "unprognostic (2.97e-2)" "unprognostic (5.19e-2)" "unprognostic (2.34e-1)" "unprognostic (9.28e-2)" "unprognostic (1.65e-2)" "unprognostic (6.35e-3)" "potential prognostic favorable (1.36e-4)" "unprognostic (9.12e-3)" "unprognostic (9.36e-3)" "unprognostic (7.16e-3)" "unprognostic (2.41e-2)" "validated prognostic unfavorable (2.27e-4)" "validated prognostic unfavorable (4.50e-4)" "unprognostic (1.88e-1)" "unprognostic (1.14e-1)" "unprognostic (3.78e-2)" "unprognostic (1.95e-1)" "potential prognostic unfavorable (2.38e-4)" "unprognostic (1.27e-1)" "unprognostic (1.31e-1)" "unprognostic (4.90e-2)" "potential prognostic favorable (1.23e-4)" "unprognostic (4.12e-2)" "unprognostic (3.17e-1)" "unprognostic (3.42e-1)" "unprognostic (4.24e-1)" "unprognostic (2.81e-2)" SMAD4 "DPC4, MADH4" ENSG00000141646 "SMAD family member 4" Q13485 18 51028394-51085045 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 7055256.0" "Tissue enhanced" "Detected in many" "blood vessel: 63497905.5;Stomach: 92021087.8" "HPA019154, CAB080136" Approved Supported "Nucleoplasm,Vesicles,Primary cilium tip,Centrosome,Basal body,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 22: Non-specific - Basic cellular functions" 183 "Nucleoplasm, Centrosome, Basal body" "Vesicles, Primary cilium tip, Cytosol" "CAB080136: , HPA019154: " "unprognostic (2.13e-3)" "unprognostic (2.64e-1)" "unprognostic (3.40e-2)" "unprognostic (3.26e-2)" "unprognostic (2.14e-1)" "unprognostic (2.05e-1)" "unprognostic (5.94e-2)" "unprognostic (5.31e-3)" "unprognostic (1.29e-1)" "unprognostic (1.16e-2)" "validated prognostic favorable (6.82e-5)" "validated prognostic favorable (9.35e-5)" "unprognostic (2.62e-3)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (1.21e-1)" "unprognostic (9.51e-2)" "unprognostic (3.96e-1)" "unprognostic (1.56e-2)" "unprognostic (4.76e-1)" "unprognostic (2.29e-1)" "unprognostic (6.76e-3)" "unprognostic (2.16e-1)" "unprognostic (1.70e-1)" "unprognostic (2.41e-1)" "unprognostic (2.42e-1)" "unprognostic (5.54e-2)" "unprognostic (1.51e-1)" "unprognostic (1.74e-1)" "unprognostic (3.79e-2)" "unprognostic (4.05e-1)" SMAD7 "MADH7, MADH8" ENSG00000101665 "SMAD family member 7" O15105 18 48919853-48950965 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 49.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 115.2;Endometrial glandular cells: 64.5;Endometrial luminal cells: 81.7;Vascular endothelial cells: 64.2" "Cell type enhanced" "Detected in many" "Alveolar cells: 115.2" "Cell type enhanced" "Detected in all" "endothelial cell: 88.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 4.5;eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Prostate - Fibroblasts, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB026212, HPA028897" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Centrosome,Basal body,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 25: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 58 "Nucleoplasm, Centrosome, Basal body" "Nucleoli fibrillar center, Cytosol" "CAB026212: , HPA028897: " "unprognostic (1.25e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.94e-1)" "unprognostic (2.17e-1)" "unprognostic (2.71e-1)" "unprognostic (9.22e-2)" "unprognostic (3.46e-1)" "unprognostic (9.39e-2)" "potential prognostic favorable (3.24e-5)" "unprognostic (9.98e-3)" "unprognostic (9.85e-3)" "unprognostic (1.18e-1)" "unprognostic (9.74e-2)" "unprognostic (5.66e-3)" "unprognostic (6.20e-2)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (2.79e-1)" "unprognostic (4.40e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (9.55e-2)" "unprognostic (2.97e-1)" "unprognostic (3.11e-2)" "unprognostic (1.53e-1)" "unprognostic (3.85e-1)" "unprognostic (2.05e-1)" "unprognostic (9.09e-2)" "unprognostic (8.85e-3)" "unprognostic (5.63e-2)" SMARCA4 "BAF190, BRG1, FLJ39786, hSNF2b, SNF2, SNF2-BETA, SNF2L4, SNF2LB, SWI2" ENSG00000127616 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4" P51532 19 10960932-11079426 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase, Repressor, RNA-binding" "Cancer-related genes, Deafness, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 342.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 18239547.3;Neurons: 10203987.3" "Low tissue specificity" "Detected in many" "CAB004208, HPA048340" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Nucleoli rim" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 232 "Nucleoplasm, Nucleoli fibrillar center, Nucleoli rim" "CAB004208: , HPA048340: " "unprognostic (6.70e-2)" "unprognostic (3.03e-2)" "unprognostic (1.15e-1)" "unprognostic (1.98e-1)" "unprognostic (8.09e-2)" "unprognostic (3.24e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-2)" "unprognostic (3.06e-2)" "unprognostic (7.14e-2)" "unprognostic (3.56e-2)" "unprognostic (2.66e-1)" "unprognostic (3.02e-2)" "validated prognostic unfavorable (1.42e-4)" "validated prognostic unfavorable (2.19e-5)" "unprognostic (5.87e-2)" "unprognostic (4.99e-3)" "unprognostic (8.85e-2)" "unprognostic (1.02e-2)" "unprognostic (2.54e-2)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (3.23e-3)" "unprognostic (3.56e-2)" "unprognostic (1.18e-1)" "unprognostic (4.06e-2)" "potential prognostic unfavorable (8.18e-6)" "unprognostic (6.01e-2)" "unprognostic (8.14e-2)" "unprognostic (3.17e-1)" "unprognostic (1.30e-1)" SMARCA5 "hISWI, hSNF2H, ISWI" ENSG00000153147 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5" O60264 4 143513702-143557486 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction" "Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "CAB005227, HPA008751" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" No No 4200 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 143 Nucleoplasm "Nucleoli fibrillar center" "CAB005227: , HPA008751: " "unprognostic (6.74e-2)" "unprognostic (8.31e-3)" "unprognostic (1.35e-2)" "unprognostic (1.62e-2)" "unprognostic (3.43e-2)" "unprognostic (5.00e-2)" "unprognostic (1.92e-1)" "unprognostic (2.09e-1)" "unprognostic (1.97e-1)" "unprognostic (9.65e-3)" "validated prognostic favorable (2.03e-6)" "validated prognostic favorable (2.05e-4)" "unprognostic (8.58e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (2.01e-1)" "unprognostic (1.16e-1)" "unprognostic (1.23e-1)" "unprognostic (9.81e-2)" "unprognostic (4.72e-2)" "unprognostic (2.55e-2)" "unprognostic (3.57e-3)" "unprognostic (1.16e-1)" "unprognostic (4.09e-2)" "unprognostic (6.46e-2)" "unprognostic (7.98e-2)" "unprognostic (2.47e-2)" "unprognostic (1.07e-1)" "unprognostic (2.67e-1)" "unprognostic (4.86e-1)" "unprognostic (5.09e-2)" "unprognostic (2.36e-1)" SMARCAL1 "HARP, HHARP" ENSG00000138375 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1" Q9NZC9 2 216412383-216483053 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1455146.7" "Tissue enriched" "Detected in single" 3693 "lymphoid tissue: 369334.9" HPA020337 Uncertain Supported Nucleoplasm NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 54: Non-specific - Ribosome" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 10 Nucleoplasm "HPA020337: " "unprognostic (1.06e-1)" "unprognostic (4.40e-2)" "unprognostic (9.93e-2)" "unprognostic (4.82e-2)" "unprognostic (3.66e-1)" "unprognostic (1.57e-1)" "unprognostic (1.09e-1)" "unprognostic (5.06e-2)" "unprognostic (3.47e-2)" "unprognostic (9.93e-2)" "potential prognostic favorable (6.24e-4)" "unprognostic (1.62e-1)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (1.03e-4)" "unprognostic (9.08e-3)" "unprognostic (2.81e-3)" "unprognostic (1.40e-2)" "unprognostic (6.28e-2)" "unprognostic (5.47e-1)" "unprognostic (1.57e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-1)" "unprognostic (3.51e-3)" "unprognostic (4.59e-1)" "unprognostic (6.25e-2)" "unprognostic (1.84e-1)" "unprognostic (3.23e-2)" "unprognostic (2.72e-1)" "unprognostic (4.34e-2)" "unprognostic (1.26e-1)" "unprognostic (2.20e-1)" SMARCD3 "BAF60C, CRACD3, Rsc6p" ENSG00000082014 "SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3" Q6STE5 7 151238764-151277896 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 148.9;skeletal muscle: 120.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 159.6;Myonuclei: 135.5;Neutrophils: 107.1;Pericytes: 88.1;Peritubular myoid cells: 107.0;Vascular smooth muscle cells: 120.9" "Cell type enhanced" "Detected in many" "Mural cells: 120.9;Myocytes: 135.5;Secretory cells: 159.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 109.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 5.5" "Group enriched" "Detected in many" 5 "dendritic cells: 1.6;granulocytes: 1.9;monocytes: 5.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Capillaries: 5731062.0;Granulosa cells: 6767300.0;Neurons: 11822341.3" "Tissue enhanced" "Detected in some" "cerebral cortex: 12171583.0;ovary: 24363802.0" "HPA063955, HPA065517" Uncertain Enhanced Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 110: Mural cells - ECM organization" 22 Nucleoplasm "HPA063955: , HPA065517: " "unprognostic (2.11e-2)" "unprognostic (2.46e-2)" "unprognostic (1.44e-1)" "unprognostic (2.42e-2)" "unprognostic (1.30e-1)" "unprognostic (3.65e-3)" "unprognostic (2.87e-2)" "unprognostic (4.71e-2)" "unprognostic (2.31e-3)" "unprognostic (5.24e-2)" "unprognostic (5.11e-2)" "unprognostic (1.15e-1)" "unprognostic (1.20e-2)" "unprognostic (2.84e-2)" "unprognostic (7.05e-2)" "potential prognostic favorable (5.62e-6)" "unprognostic (2.00e-1)" "unprognostic (2.91e-2)" "unprognostic (1.05e-1)" "unprognostic (3.86e-2)" "unprognostic (5.37e-3)" "potential prognostic favorable (8.70e-4)" "unprognostic (1.54e-1)" "unprognostic (1.11e-1)" "unprognostic (1.80e-1)" "unprognostic (3.77e-2)" "unprognostic (4.69e-2)" "unprognostic (3.48e-3)" "unprognostic (1.20e-1)" "unprognostic (1.26e-1)" "unprognostic (2.41e-1)" SMC2 "CAP-E, hCAP-E, SMC2L1" ENSG00000136824 "Structural maintenance of chromosomes 2" O95347 9 104094260-104141419 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA condensation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 24.0" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 120.6;Endometrial ciliated cells: 142.7;Epididymal efferent duct ciliated cells: 128.4;Erythrocyte progenitors: 251.2;Megakaryocyte progenitors: 187.1;Monocyte progenitors: 185.1;Oocytes: 124.3" "Cell type enhanced" "Detected in all" "Erythrocytes: 251.2;Megakaryocytes: 187.1;Mononuclear phagocytes: 185.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 22049846.1;Neutrophils: 21170936.1" "Group enriched" "Detected in some" "bone marrow: 8009872.2;ovary: 24906721.9" HPA071309 Approved Supported Nucleoplasm,Nucleoli Yes No 9100 "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Cell proliferation" 47 Nucleoplasm Nucleoli "HPA071309: " "unprognostic (3.71e-2)" "unprognostic (1.57e-1)" "unprognostic (1.54e-3)" "unprognostic (7.71e-2)" "unprognostic (1.10e-1)" "unprognostic (5.55e-2)" "unprognostic (2.12e-1)" "unprognostic (8.00e-2)" "unprognostic (1.20e-1)" "unprognostic (3.94e-2)" "potential prognostic favorable (6.85e-7)" "unprognostic (4.45e-2)" "unprognostic (1.14e-1)" "unprognostic (2.35e-3)" "potential prognostic unfavorable (4.22e-4)" "potential prognostic unfavorable (4.44e-5)" "unprognostic (1.70e-3)" "unprognostic (2.02e-1)" "unprognostic (1.33e-1)" "unprognostic (2.03e-1)" "unprognostic (2.43e-2)" "unprognostic (2.01e-2)" "unprognostic (9.00e-2)" "unprognostic (5.88e-2)" "unprognostic (5.28e-3)" "unprognostic (7.42e-2)" "unprognostic (2.39e-2)" "unprognostic (5.48e-2)" "unprognostic (1.62e-1)" "unprognostic (2.69e-1)" "unprognostic (2.83e-1)" SMG1 "ATX, KIAA0421, LIP" ENSG00000157106 "SMG1 nonsense mediated mRNA decay associated PI3K related kinase" Q96Q15 16 18804860-18926408 "Enzymes, Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Nonsense-mediated mRNA decay" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 462.9;Thymic myoid cells: 610.5" "Cell type enhanced" "Detected in all" "Stromal cells: 610.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 34.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "bone marrow: 2871737.2;cerebral cortex: 985409.8;intestine: 1397315.2;lymphoid tissue: 3236558.1" "HPA006870, HPA031623, HPA073972" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions,Primary cilium" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 24 Nucleoplasm "Vesicles, Plasma membrane, Cell Junctions, Primary cilium" "HPA006870: , HPA031623: , HPA073972: " "unprognostic (4.88e-2)" "unprognostic (6.37e-2)" "unprognostic (2.50e-1)" "unprognostic (5.25e-2)" "unprognostic (1.53e-1)" "unprognostic (2.86e-1)" "unprognostic (4.95e-2)" "unprognostic (1.80e-2)" "unprognostic (1.25e-2)" "unprognostic (8.94e-3)" "unprognostic (5.32e-3)" "unprognostic (1.88e-3)" "unprognostic (3.88e-1)" "unprognostic (3.99e-2)" "unprognostic (2.55e-1)" "unprognostic (2.44e-1)" "unprognostic (9.31e-2)" "unprognostic (1.41e-1)" "unprognostic (6.32e-3)" "unprognostic (1.27e-1)" "unprognostic (3.80e-2)" "validated prognostic unfavorable (6.55e-5)" "validated prognostic unfavorable (1.90e-4)" "unprognostic (9.91e-2)" "potential prognostic favorable (1.53e-4)" "unprognostic (4.67e-3)" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (3.20e-2)" "unprognostic (1.86e-1)" SMG5 "EST1B, KIAA1089, LPTS-RP1, LPTSRP1, RP11-54H19.7, SMG-5" ENSG00000198952 "SMG5 nonsense mediated mRNA decay factor" Q9UPR3 1 156249224-156282825 "Essential proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "lymphoid tissue: 362232.1" HPA072651 Supported "Plasma membrane,Primary cilium,Cytoplasmic bodies" No No "Cluster 25: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 18: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 9 "Cytoplasmic bodies" "Plasma membrane, Primary cilium" "HPA072651: " "unprognostic (4.56e-2)" "unprognostic (5.33e-2)" "unprognostic (1.01e-1)" "unprognostic (1.95e-2)" "unprognostic (3.49e-1)" "unprognostic (2.99e-1)" "unprognostic (2.16e-1)" "potential prognostic favorable (7.31e-4)" "unprognostic (5.59e-3)" "unprognostic (1.19e-2)" "unprognostic (2.29e-2)" "unprognostic (6.78e-2)" "unprognostic (9.10e-3)" "potential prognostic unfavorable (9.06e-9)" "unprognostic (2.49e-2)" "unprognostic (5.48e-2)" "unprognostic (1.22e-3)" "unprognostic (9.50e-2)" "unprognostic (2.09e-1)" "unprognostic (4.92e-2)" "unprognostic (1.48e-1)" "unprognostic (1.25e-1)" "unprognostic (3.58e-2)" "unprognostic (2.92e-2)" "unprognostic (3.66e-2)" "unprognostic (1.09e-2)" "unprognostic (2.98e-2)" "unprognostic (4.16e-2)" "unprognostic (2.59e-1)" "unprognostic (2.77e-1)" "unprognostic (1.40e-2)" SMG8 "C17orf71, FLJ10587, FLJ23205" ENSG00000167447 "SMG8 nonsense mediated mRNA decay factor" Q8ND04 17 59209400-59215239 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Cataract, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.0;Brain excitatory neurons: 4.2;Brain inhibitory neurons: 4.3;Ependymal cells: 3.9;Foveolar cells: 3.2;Microglia: 3.6;Oligodendrocyte progenitor cells: 3.8;Oligodendrocytes: 4.9;Other brain neurons: 6.9;Smooth muscle cells: 3.2" "Cell type enhanced" "Detected in some" "Glial cells: 5.0;Neuronal cells: 6.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Spleen - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA024841 Approved Approved "Nucleoplasm,Vesicles,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 7 Nucleoplasm "Vesicles, Primary cilium, Primary cilium tip, Cytosol" "HPA024841: " "unprognostic (1.96e-1)" "unprognostic (1.05e-2)" "unprognostic (7.66e-2)" "unprognostic (2.89e-2)" "unprognostic (3.01e-2)" "unprognostic (1.70e-1)" "unprognostic (1.19e-2)" "unprognostic (4.12e-1)" "unprognostic (3.54e-3)" "potential prognostic favorable (1.07e-5)" "unprognostic (1.60e-2)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (5.49e-4)" "unprognostic (1.26e-3)" "unprognostic (1.88e-1)" "unprognostic (6.45e-3)" "unprognostic (2.32e-1)" "unprognostic (6.08e-3)" "unprognostic (1.19e-1)" "unprognostic (8.27e-3)" "unprognostic (3.38e-2)" "unprognostic (8.58e-2)" "unprognostic (6.73e-2)" "unprognostic (1.74e-3)" "unprognostic (1.17e-1)" "unprognostic (8.34e-2)" "unprognostic (1.75e-1)" "unprognostic (3.10e-1)" "unprognostic (2.77e-1)" "unprognostic (1.04e-1)" SMIM24 "C19orf77, HSPC323" ENSG00000095932 "Small integral membrane protein 24" O75264 19 3473986-3480525 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "epididymis: 1491.1;intestine: 708.4;kidney: 785.7" "Group enriched" "Detected in many" 5 "Enterocytes: 3849.8;Epididymal efferent duct absorptive cells: 1015.5;Epididymal principal cells: 2513.0" "Group enriched" "Detected in many" 6 "Ductal cells: 1015.5;Enterocytes: 3849.8;Reproductive supporting cells: 2513.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 728.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Gastric cancer: 35.6;Leukemia: 96.4" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Pancreas - Alpha cells, Prostate - Prostate glandular cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" "Glomeruli: 28933880.7;Proximal tubules: 26985543.6" "Tissue enriched" "Detected in some" "kidney: 69281864.0" "HPA045046, HPA056027" Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 15: NK-cells - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" Nucleoplasm Cytosol "HPA045046: , HPA056027: " "unprognostic (5.66e-3)" "unprognostic (3.00e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-1)" "unprognostic (1.42e-1)" "unprognostic (8.57e-2)" "validated prognostic favorable (3.19e-10)" "validated prognostic favorable (3.74e-6)" "unprognostic (4.98e-2)" "unprognostic (1.38e-1)" "unprognostic (3.26e-1)" "unprognostic (3.38e-2)" "unprognostic (2.03e-2)" "unprognostic (1.28e-1)" "unprognostic (1.06e-1)" "unprognostic (2.67e-1)" "unprognostic (2.27e-1)" "unprognostic (1.93e-2)" "unprognostic (1.38e-1)" "unprognostic (3.46e-1)" "unprognostic (2.33e-1)" "unprognostic (1.84e-2)" "unprognostic (2.12e-1)" "unprognostic (2.15e-1)" "unprognostic (3.00e-1)" SMIM6 "C17orf110, ELN" ENSG00000259120 "Small integral membrane protein 6" P0DI80 17 75646243-75647975 "Predicted membrane proteins, Transporters" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.7;kidney: 21.7;stomach 1: 31.3;testis: 25.1" "Group enriched" "Detected in many" 6 "Early spermatids: 659.2;Late spermatids: 1695.6" "Cell type enriched" "Detected in many" 9 "Spermatogenic cell types: 1695.6" "Cell type enriched" "Detected in some" 6 "oligodendrocyte: 7.9" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 42 "plasmacytoid DC: 34.2" "Lineage enriched" "Detected in single" 42 "dendritic cells: 34.2" "Cancer enhanced" "Detected in many" "Gastric cancer: 9.2;Kidney cancer: 9.2" "Adipose visceral - Mesothelial cells, Colon - Colon enterocytes, Kidney - Intercalated cells, Lung - Respiratory ciliated cells, Stomach - Gastric mucous cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA065721 Uncertain Approved Nucleoplasm Yes NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 11: White matter - Signal transduction" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" Nucleoplasm "HPA065721: " "unprognostic (1.68e-1)" "unprognostic (5.40e-3)" "unprognostic (1.07e-2)" "unprognostic (1.51e-1)" "unprognostic (8.81e-3)" "unprognostic (7.59e-2)" "unprognostic (9.08e-2)" "unprognostic (9.42e-2)" "unprognostic (4.98e-2)" "unprognostic (1.04e-1)" "unprognostic (7.79e-2)" "unprognostic (1.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.13e-2)" "unprognostic (1.24e-1)" "unprognostic (9.90e-2)" "unprognostic (9.02e-2)" "unprognostic (3.44e-1)" "unprognostic (3.42e-3)" SMN1 "BCD541, GEMIN1, SMA, SMA@, SMA1, SMA2, SMA3, SMNT, TDRD16A" ENSG00000172062 "Survival of motor neuron 1, telomeric" Q16637 5 70925030-70953942 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 16.9;Late primary spermatocytes: 15.1;Late spermatids: 17.0;Megakaryocytes: 12.4;Oocytes: 9.2" "Cell type enhanced" "Detected in many" "Megakaryocytes: 12.4;Spermatogenic cell types: 17.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Cell type enriched" "Detected in many" "Granulosa cells: 6761970.2" "Tissue enhanced" "Detected in many" "bone marrow: 6171096.4;kidney: 3719015.8" "CAB016324, HPA045271, CAB069888, HPA073601" Supported Supported "Nuclear bodies,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 184 "Nuclear bodies, Cytosol" "CAB016324: , CAB069888: , HPA045271: , HPA073601: " "unprognostic (5.26e-2)" "unprognostic (4.08e-2)" "unprognostic (3.19e-1)" "unprognostic (3.92e-2)" "unprognostic (2.15e-1)" "unprognostic (1.15e-2)" "unprognostic (3.75e-1)" "potential prognostic unfavorable (1.52e-4)" "unprognostic (8.44e-2)" "unprognostic (7.66e-2)" "unprognostic (4.66e-3)" "unprognostic (1.52e-1)" "unprognostic (5.14e-2)" "unprognostic (2.31e-2)" "unprognostic (5.58e-3)" "unprognostic (1.99e-2)" "unprognostic (9.60e-3)" "unprognostic (4.02e-2)" "unprognostic (1.79e-1)" "unprognostic (6.93e-2)" "unprognostic (9.63e-2)" "unprognostic (1.89e-1)" "potential prognostic unfavorable (7.63e-4)" "unprognostic (1.05e-1)" "unprognostic (3.16e-1)" "unprognostic (6.75e-3)" "unprognostic (9.03e-2)" "unprognostic (2.44e-1)" "unprognostic (3.01e-2)" "unprognostic (6.69e-3)" "unprognostic (4.22e-2)" SMN2 "BCD541, GEMIN1, SMNC, TDRD16B" ENSG00000205571 "Survival of motor neuron 2, centromeric" Q16637 5 70049638-70078522 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Neurogenesis" RNA-binding "Disease variant, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 7.7;Bergmann glia: 12.0;Brain excitatory neurons: 10.5;Brain inhibitory neurons: 8.7;Choroid plexus epithelial cells: 7.5;Early spermatids: 13.7;Ependymal cells: 7.4;Late primary spermatocytes: 8.8;Late spermatids: 9.5;Microglia: 7.5;Oligodendrocyte progenitor cells: 8.2;Oligodendrocytes: 8.2;Other brain neurons: 8.5" "Cell type enhanced" "Detected in some" "Ciliated cells: 7.5;Glial cells: 12.0;Neuronal cells: 10.5;Spermatogenic cell types: 13.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in many" "Granulosa cells: 6761970.2" "Tissue enhanced" "Detected in many" "bone marrow: 6171096.4;kidney: 3719015.8" "CAB009344, HPA045271, HPA073601" Supported Supported "Nuclear bodies,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 74: Non-specific - Signal transduction" "Cluster 27: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" 86 "Nuclear bodies, Cytosol" "CAB009344: , HPA045271: , HPA073601: " "unprognostic (1.68e-1)" "unprognostic (2.71e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (7.02e-4)" "unprognostic (3.02e-2)" "unprognostic (2.65e-1)" "unprognostic (1.84e-1)" "unprognostic (9.87e-2)" "unprognostic (3.11e-1)" "unprognostic (8.62e-2)" "unprognostic (2.53e-1)" "unprognostic (2.02e-1)" "unprognostic (1.71e-1)" "unprognostic (1.39e-3)" "unprognostic (5.58e-3)" "unprognostic (1.17e-1)" "unprognostic (8.50e-2)" "unprognostic (1.96e-1)" "unprognostic (3.06e-1)" "unprognostic (2.76e-1)" "unprognostic (5.85e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (2.50e-5)" "unprognostic (7.77e-2)" "unprognostic (2.08e-1)" "unprognostic (6.85e-2)" "unprognostic (3.07e-2)" "unprognostic (2.96e-1)" "unprognostic (1.84e-1)" "unprognostic (1.62e-1)" "unprognostic (9.97e-2)" SMO "FZD11, SMOH" ENSG00000128602 "Smoothened, frizzled class receptor" Q99835 7 129188633-129213545 "Cancer-related genes, Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 41.8;Bergmann glia: 41.9;Choroid plexus epithelial cells: 38.9;Ependymal cells: 38.0;Lactotrophs: 33.7;Leydig cells: 39.5;Peritubular myoid cells: 43.8;Pituitary stem cells: 49.1;Podocytes: 37.4;Proximal tubule cells: 37.8;Somatotrophs: 36.1;Thyrotrophs: 41.7" "Cell type enhanced" "Detected in many" "Stem cells: 49.1" "Group enriched" "Detected in many" 4 "astrocyte: 55.6;Bergmann glia: 40.6;choroid plexus epithelial cell: 29.2;ependymal cell: 44.3;fibroblast: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Liver - Hepatocytes, Lung - Fibroblasts_2, Spleen - Fibroblasts_1, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Glomeruli: 81829.4" "Not detected" "Not detected" "CAB011446, CAB080590" Approved Supported "Golgi apparatus,Plasma membrane,Primary cilium" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 5: Rhabdoid - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 3 "Golgi apparatus, Plasma membrane, Primary cilium" "CAB011446: , CAB080590: " "unprognostic (2.73e-1)" "unprognostic (3.93e-2)" "unprognostic (5.42e-2)" "unprognostic (5.91e-2)" "unprognostic (3.34e-2)" "unprognostic (2.98e-1)" "unprognostic (1.28e-1)" "unprognostic (2.09e-3)" "unprognostic (2.43e-1)" "unprognostic (1.15e-1)" "unprognostic (2.32e-2)" "unprognostic (7.30e-2)" "unprognostic (6.60e-2)" "unprognostic (2.58e-1)" "unprognostic (4.01e-2)" "unprognostic (1.13e-2)" "unprognostic (1.69e-2)" "unprognostic (2.20e-1)" "unprognostic (7.14e-3)" "unprognostic (2.25e-1)" "unprognostic (1.59e-1)" "unprognostic (1.86e-2)" "unprognostic (2.44e-1)" "unprognostic (3.36e-2)" "unprognostic (1.59e-1)" "unprognostic (1.09e-1)" "potential prognostic unfavorable (9.61e-5)" "unprognostic (1.48e-3)" "unprognostic (5.21e-2)" "unprognostic (1.06e-1)" "unprognostic (2.76e-1)" SMOX "C20orf16, dJ779E11.1, FLJ20746, MGC1010, PAO, PAOh1, SMO" ENSG00000088826 "Spermine oxidase" Q9NWM0 20 4120980-4187747 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 62.6" "Cell type enriched" "Detected in many" 5 "Platelets: 917.1" "Cell type enriched" "Detected in many" 5 "Platelets: 917.1" "Cell type enhanced" "Detected in many" "astrocyte: 91.6;Bergmann glia: 44.0" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 83.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 1.0;myeloid DC: 2.4;neutrophil: 3.6;plasmacytoid DC: 1.1" "Group enriched" "Detected in many" 6 "dendritic cells: 2.4;granulocytes: 3.6;monocytes: 1.0" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Kidney - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047117, HPA060198" Approved Supported "Nucleoplasm,Nuclear membrane,Vesicles,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Platelets - Hemostasis" Nucleoplasm "Nuclear membrane, Vesicles, Cytosol" "HPA047117: , HPA060198: " "unprognostic (5.25e-3)" "unprognostic (4.04e-2)" "unprognostic (2.11e-2)" "unprognostic (1.41e-3)" "unprognostic (6.70e-2)" "unprognostic (1.33e-1)" "unprognostic (1.36e-1)" "unprognostic (5.71e-2)" "unprognostic (1.35e-1)" "unprognostic (1.92e-1)" "unprognostic (1.22e-2)" "unprognostic (5.25e-2)" "unprognostic (7.40e-2)" "validated prognostic unfavorable (1.69e-7)" "validated prognostic unfavorable (2.26e-4)" "potential prognostic unfavorable (2.32e-4)" "unprognostic (3.09e-2)" "unprognostic (2.97e-2)" "unprognostic (1.31e-1)" "unprognostic (8.87e-2)" "unprognostic (2.92e-1)" "unprognostic (1.15e-2)" "unprognostic (1.94e-1)" "unprognostic (2.11e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (7.15e-2)" "unprognostic (1.13e-1)" "unprognostic (2.01e-3)" "unprognostic (6.09e-2)" "unprognostic (1.02e-1)" SMPD4 "FLJ20297, FLJ20756, KIAA1418, NET13, nSMase-3, NSMASE3" ENSG00000136699 "Sphingomyelin phosphodiesterase 4" Q9NXE4 2 130151392-130182750 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Pituitary gland - Somatotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 21901635.8" "Tissue enriched" "Detected in many" "intestine: 75889777.2" "HPA046279, HPA049426" Approved Approved "Nuclear membrane,Cytosol" NA Yes "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 44: Plasma cells - Antibody production & secretion" 6 "Nuclear membrane" Cytosol "HPA046279: , HPA049426: " "unprognostic (2.36e-1)" "unprognostic (2.78e-1)" "unprognostic (4.08e-2)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (9.81e-2)" "unprognostic (2.57e-1)" "unprognostic (9.87e-3)" "unprognostic (5.79e-2)" "unprognostic (1.62e-1)" "potential prognostic favorable (4.28e-5)" "unprognostic (5.11e-1)" "unprognostic (2.32e-2)" "validated prognostic unfavorable (2.37e-4)" "validated prognostic unfavorable (2.58e-4)" "potential prognostic unfavorable (3.11e-4)" "unprognostic (4.41e-3)" "unprognostic (4.41e-1)" "unprognostic (9.92e-2)" "unprognostic (2.69e-1)" "unprognostic (1.19e-2)" "potential prognostic unfavorable (7.96e-5)" "unprognostic (4.04e-3)" "unprognostic (4.02e-2)" "unprognostic (5.04e-2)" "unprognostic (7.14e-3)" "unprognostic (7.08e-2)" "unprognostic (3.03e-1)" "unprognostic (2.35e-1)" "unprognostic (2.46e-3)" "unprognostic (1.04e-1)" SMPDL3A "ASM3A, ASML3a, FLJ20177, yR36GH4.1" ENSG00000172594 "Sphingomyelin phosphodiesterase acid like 3A" Q92484 6 122789049-122809720 "Predicted intracellular proteins, Predicted secreted proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 179.4;Cytotrophoblasts: 168.3;Enterocytes: 379.3;Foveolar cells: 150.2;Kupffer cells: 293.1;Migrating cytotrophoblasts: 166.2;Syncytiotrophoblasts: 133.8" "Cell type enhanced" "Detected in many" "Enterocytes: 379.3;Mononuclear phagocytes: 293.1;Trophoblast cells: 168.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 93.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "basophil: 81.1" "Lineage enriched" "Detected in many" 11 "granulocytes: 81.1" "Cancer enhanced" "Detected in all" "prostate cancer: 39.9" "Kidney - Proximal tubular cells, Liver - Hepatocytes, Prostate - Fibroblasts, Spleen - Macrophages, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 2151502.7;Proximal tubules: 4615541.5" "Tissue enriched" "Detected in many" "blood vessel: 10974254.4" HPA030148 Uncertain Approved Nucleoplasm,Nucleoli,Mitochondria "Secreted to blood" Enzyme No No 7000000 "Cluster 32: Basophils - Transcription" "Cluster 77: Intestine - Digestion" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Nucleoplasm, Nucleoli, Mitochondria" "HPA030148: " "unprognostic (1.46e-1)" "unprognostic (2.84e-2)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (2.30e-2)" "unprognostic (8.60e-2)" "unprognostic (2.35e-1)" "unprognostic (8.96e-3)" "unprognostic (5.41e-2)" "unprognostic (1.99e-2)" "potential prognostic favorable (1.18e-5)" "unprognostic (8.95e-3)" "unprognostic (1.54e-1)" "unprognostic (2.78e-1)" "unprognostic (1.35e-3)" "unprognostic (8.94e-2)" "unprognostic (2.88e-3)" "unprognostic (8.62e-2)" "unprognostic (4.11e-2)" "unprognostic (3.77e-1)" "unprognostic (2.38e-1)" "unprognostic (2.61e-1)" "unprognostic (2.85e-1)" "unprognostic (3.31e-1)" "unprognostic (2.94e-2)" "unprognostic (2.68e-1)" "unprognostic (3.59e-1)" "unprognostic (4.10e-2)" "unprognostic (2.36e-1)" "unprognostic (7.24e-3)" "unprognostic (5.15e-2)" SMPX "Chisel, Csl, DFN6, DFNX4" ENSG00000091482 "Small muscle protein X-linked" Q9UHP9 X 21705978-21758116 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 38 "heart muscle: 709.4;skeletal muscle: 1108.9;tongue: 1025.1" "Group enriched" "Detected in some" 6 "Cardiomyocytes: 98.9;Myonuclei: 216.0;Thymic myoid cells: 254.2" "Group enriched" "Detected in some" 7 "Myocytes: 216.0;Stromal cells: 254.2" "Group enriched" "Detected in some" 6 "cerebellar inhibitory: 6.5;mammillary body: 16.3;midbrain-derived inhibitory: 22.4;thalamic excitatory: 8.0" "Group enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 14.4;Stomach Adenocarcinoma (TCGA): 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Rhabdoid: 13.8;Sarcoma: 17.9" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "cerebellum: 19.6" "Cell type enriched" "Detected in some" "Skeletal myofibers: 40565344.3" "Group enriched" "Detected in many" "heart muscle: 67150487.0;skeletal muscle: 161331009.1" HPA077360 Approved "Plasma membrane" NA NA 24000 "Cluster 41: Striated muscle - Muscle contraction" "Cluster 38: Sub-cortical - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 46: Skeletal myocytes - Muscle structure & formation" "Plasma membrane" "HPA077360: " "unprognostic (1.42e-1)" "unprognostic (5.74e-2)" "potential prognostic unfavorable (2.64e-5)" "unprognostic (1.13e-2)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (8.54e-4)" "unprognostic (5.84e-2)" "unprognostic (6.97e-2)" "unprognostic (1.04e-2)" "unprognostic (3.37e-1)" "unprognostic (1.30e-1)" "unprognostic (1.07e-2)" "unprognostic (6.08e-3)" "unprognostic (5.88e-1)" SMS "MRSR, SPMSY, SpS, SRS" ENSG00000102172 "Spermine synthase" P52788 X 21940709-21994837 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Polyamine biosynthesis" Transferase "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 795.7;Endometrial glandular cells: 544.2;Migrating cytotrophoblasts: 721.7;Oocytes: 1639.4;Syncytiotrophoblasts: 1123.6" "Cell type enhanced" "Detected in all" "Oocytes: 1639.4;Trophoblast cells: 1123.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 496.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Oocytes: 591673590.1" "Low tissue specificity" "Detected in all" "HPA029849, HPA029852" Approved Approved "Nuclear bodies,Cytosol" No No 260000 "Cluster 7: Non-specific - Innate immune response" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 36: Non-specific - mRNA processing" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 5 "Nuclear bodies" Cytosol "HPA029849: , HPA029852: " "potential prognostic unfavorable (4.22e-4)" "potential prognostic unfavorable (5.47e-4)" "unprognostic (4.75e-2)" "unprognostic (5.97e-2)" "unprognostic (9.90e-2)" "unprognostic (5.83e-2)" "unprognostic (6.79e-2)" "unprognostic (4.26e-2)" "potential prognostic unfavorable (3.74e-4)" "unprognostic (5.97e-2)" "potential prognostic favorable (1.86e-5)" "unprognostic (4.18e-3)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (5.06e-9)" "unprognostic (1.76e-3)" "validated prognostic unfavorable (5.49e-5)" "validated prognostic unfavorable (8.14e-4)" "unprognostic (1.33e-1)" "unprognostic (3.44e-2)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "potential prognostic unfavorable (8.47e-4)" "unprognostic (7.98e-3)" "unprognostic (2.91e-1)" "unprognostic (4.12e-2)" "unprognostic (2.12e-2)" "unprognostic (2.20e-1)" "unprognostic (2.83e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (1.28e-1)" SMTN ENSG00000183963 Smoothelin P53814 22 31064105-31104757 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 441.9;intestine: 828.4;urinary bladder: 510.6" "Cell type enriched" "Detected in many" 5 "Smooth muscle cells: 1281.2" "Cell type enriched" "Detected in many" 5 "Smooth muscle cells: 1281.2" "Cell type enhanced" "Detected in many" "Bergmann glia: 246.5;pericyte: 88.0;vascular associated smooth muscle cell: 90.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Liver - Vascular endothelial cells, Lung - Smooth muscle cells, Minor Salivary Gland - Endothelial cells, Prostate - Smooth muscle cells, Testis - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Cardiomyocytes: 79038593.1;Smooth muscle cells: 221917182.6" "Tissue enhanced" "Detected in many" "intestine: 1148350606.4;Stomach: 863312510.1" "CAB001721, HPA051778, HPA058590" Enhanced Supported "Nucleoplasm,Actin filaments" No Yes 43000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 3 Nucleoplasm "Actin filaments" "CAB001721: , HPA051778: , HPA058590: " "unprognostic (2.10e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "potential prognostic unfavorable (9.59e-4)" "unprognostic (4.00e-1)" "unprognostic (1.99e-1)" "unprognostic (5.46e-2)" "unprognostic (3.53e-1)" "unprognostic (2.42e-2)" "unprognostic (5.36e-2)" "validated prognostic favorable (5.73e-5)" "validated prognostic favorable (2.93e-5)" "unprognostic (2.39e-3)" "potential prognostic unfavorable (6.96e-4)" "unprognostic (5.27e-2)" "unprognostic (4.02e-2)" "unprognostic (1.32e-2)" "unprognostic (2.85e-2)" "unprognostic (8.76e-2)" "unprognostic (2.17e-1)" "unprognostic (1.06e-1)" "unprognostic (1.36e-1)" "unprognostic (3.35e-1)" "unprognostic (5.97e-2)" "unprognostic (1.87e-1)" "unprognostic (7.60e-2)" "unprognostic (6.90e-3)" "unprognostic (4.53e-2)" "unprognostic (2.03e-1)" "unprognostic (1.75e-2)" "unprognostic (6.82e-2)" SNAP23 "HsT17016, SNAP23A, SNAP23B" ENSG00000092531 "Synaptosome associated protein 23" O00161 15 42491233-42545356 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 400.6;Megakaryocytes: 500.7;Platelets: 1140.4" "Cell type enhanced" "Detected in all" "Platelets: 1140.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 681.5" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Colon - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA001214, CAB037083, CAB037317" Approved Supported "Plasma membrane,Primary cilium" NA NA 2000000 "Cluster 35: Neutrophils - Protein binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 58: Non-specific - Nuclear processes" "Cluster 47: Platelets - Hemostasis" 57 "Plasma membrane" "Primary cilium" "CAB037083: , CAB037317: , HPA001214: " "unprognostic (2.23e-2)" "unprognostic (9.35e-2)" "unprognostic (2.00e-1)" "unprognostic (2.91e-2)" "unprognostic (6.42e-2)" "unprognostic (3.03e-1)" "unprognostic (6.93e-2)" "unprognostic (3.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.48e-3)" "unprognostic (1.06e-3)" "unprognostic (3.85e-2)" "unprognostic (2.58e-1)" "unprognostic (1.58e-3)" "unprognostic (2.42e-2)" "unprognostic (9.14e-2)" "unprognostic (2.28e-2)" "unprognostic (8.19e-2)" "unprognostic (3.43e-3)" "unprognostic (4.06e-2)" "unprognostic (3.11e-3)" "unprognostic (1.82e-2)" "unprognostic (1.36e-2)" "unprognostic (1.37e-1)" "unprognostic (6.17e-2)" "unprognostic (3.55e-2)" "unprognostic (2.86e-2)" "unprognostic (4.95e-2)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "unprognostic (1.46e-1)" SNAPC1 "PTFgamma, SNAP43" ENSG00000023608 "Small nuclear RNA activating complex polypeptide 1" Q16533 14 61762420-61796428 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 139.6;Late primary spermatocytes: 150.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 374032.6" "Not detected" "Not detected" "HPA067076, HPA072276" Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 72: Neuronal - Signal transduction" "Cluster 51: Secretory epithelial cells - Mixed function" 23 Nucleoli Nucleoplasm "HPA067076: , HPA072276: " "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (6.04e-2)" "unprognostic (1.11e-2)" "unprognostic (2.30e-2)" "unprognostic (1.98e-1)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (2.30e-2)" "unprognostic (2.40e-2)" "unprognostic (2.16e-3)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (3.08e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (2.49e-5)" "unprognostic (6.99e-3)" "unprognostic (3.88e-1)" "unprognostic (2.29e-1)" "unprognostic (1.58e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-3)" "unprognostic (1.86e-1)" "unprognostic (2.05e-1)" "unprognostic (1.55e-1)" "unprognostic (7.81e-2)" "unprognostic (6.30e-2)" "unprognostic (1.43e-1)" "unprognostic (2.02e-1)" "unprognostic (1.25e-1)" SNAPC4 "FLJ13451, PTFalpha, SNAP190" ENSG00000165684 "Small nuclear RNA activating complex polypeptide 4" Q5SXM2 9 136375567-136400176 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Respiratory ciliated cells: 39.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 238267.4;Oocytes: 143041.1" "Group enriched" "Detected in some" 12205 "intestine: 1652581.6;skeletal muscle: 1336314.5;Stomach: 672733.0" "HPA028939, HPA046627, HPA073243" Uncertain Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 61: Non-specific - Transcription" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 34: Ciliated cells - Cilia assembly & function" 13 "Nucleoplasm, Nuclear membrane" "HPA028939: , HPA046627: , HPA073243: " "unprognostic (2.15e-1)" "unprognostic (1.32e-2)" "unprognostic (2.63e-3)" "unprognostic (7.85e-2)" "unprognostic (1.23e-1)" "unprognostic (1.52e-1)" "unprognostic (9.34e-2)" "unprognostic (2.51e-3)" "unprognostic (5.50e-2)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (5.83e-2)" "unprognostic (1.38e-1)" "unprognostic (7.89e-3)" "unprognostic (1.42e-1)" "unprognostic (3.89e-1)" "potential prognostic unfavorable (4.19e-4)" "unprognostic (2.09e-1)" "potential prognostic favorable (7.94e-4)" "unprognostic (1.87e-1)" "unprognostic (3.48e-3)" "unprognostic (1.16e-3)" "unprognostic (1.31e-1)" "unprognostic (9.69e-2)" "unprognostic (4.36e-3)" "unprognostic (1.39e-2)" "unprognostic (2.56e-1)" "unprognostic (6.23e-2)" "unprognostic (7.95e-3)" "unprognostic (9.95e-3)" "unprognostic (1.80e-2)" SNPH bA314N13.5 ENSG00000101298 Syntaphilin O15079 20 1266280-1309328 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 72.8" "Cell type enhanced" "Detected in many" "Astrocytes: 21.2;Brain excitatory neurons: 20.9;Brain inhibitory neurons: 23.6;Breast lactating cells: 11.8;Early spermatids: 13.0;Oligodendrocyte progenitor cells: 20.9;Other brain neurons: 19.7;Retinal amacrine cells: 13.7;Retinal bipolar cells: 14.5;Retinal horizontal cells: 20.0" "Cell type enhanced" "Detected in many" "Glial cells: 21.2;Neuronal cells: 23.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.0;naive CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 9 "T-cells: 1.0" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 67841 "Astrocytes and Neuropil: 7564050.3;Microglia and Neuropil: 8820616.7;Neurons: 3967617.3" "Tissue enriched" "Detected in single" 121394 "cerebral cortex: 12139387.9" HPA049393 Approved Uncertain "Cytokinetic bridge,Mitochondria" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" 5 Mitochondria "Cytokinetic bridge" "HPA049393: " "unprognostic (7.07e-2)" "unprognostic (4.34e-2)" "unprognostic (1.83e-1)" "unprognostic (1.12e-2)" "unprognostic (6.81e-2)" "unprognostic (1.46e-1)" "unprognostic (3.09e-2)" "unprognostic (2.15e-1)" "unprognostic (2.74e-1)" "unprognostic (1.33e-2)" "unprognostic (1.92e-1)" "unprognostic (2.44e-1)" "potential prognostic favorable (7.31e-5)" "unprognostic (9.87e-2)" "unprognostic (3.79e-3)" "unprognostic (9.91e-2)" "potential prognostic favorable (4.28e-4)" "unprognostic (5.74e-2)" "unprognostic (1.31e-1)" "unprognostic (5.33e-2)" "unprognostic (2.71e-1)" "unprognostic (1.86e-1)" "unprognostic (3.76e-2)" "unprognostic (9.82e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-2)" SNRNP200 "ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD" ENSG00000144028 "Small nuclear ribonucleoprotein U5 subunit 200" O75643 2 96274338-96321271 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Helicase, Hydrolase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA029321 Approved Supported "Nucleoplasm,Primary cilium,Cytosol" NA NA 290000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 17: Non-specific - RNA processing" 177 Nucleoplasm "Primary cilium, Cytosol" "HPA029321: " "unprognostic (5.74e-2)" "unprognostic (2.56e-2)" "unprognostic (1.67e-1)" "unprognostic (2.17e-2)" "unprognostic (1.58e-1)" "unprognostic (8.68e-2)" "unprognostic (1.87e-2)" "unprognostic (2.95e-1)" "unprognostic (7.87e-2)" "potential prognostic unfavorable (8.40e-7)" "validated prognostic favorable (2.19e-7)" "validated prognostic favorable (1.87e-4)" "unprognostic (4.79e-1)" "unprognostic (5.34e-2)" "unprognostic (4.92e-3)" "unprognostic (8.79e-2)" "unprognostic (1.08e-2)" "unprognostic (2.37e-2)" "unprognostic (6.41e-2)" "unprognostic (2.54e-2)" "unprognostic (9.12e-2)" "unprognostic (5.78e-2)" "unprognostic (3.11e-2)" "unprognostic (1.23e-1)" "unprognostic (2.78e-2)" "unprognostic (7.41e-3)" "unprognostic (1.68e-1)" "unprognostic (7.49e-2)" "unprognostic (2.80e-1)" "unprognostic (1.71e-3)" "unprognostic (1.56e-1)" SNRNP25 "C16orf33, U11/U12-25K" ENSG00000161981 "Small nuclear ribonucleoprotein U11/U12 subunit 25" Q9BV90 16 53828-57669 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 123.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 151.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 220.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Stomach - Mitotic cells (Stomach), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041183, HPA044248" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 21 Nucleoplasm "Cytokinetic bridge, Cytosol" "HPA041183: , HPA044248: " "unprognostic (1.06e-2)" "unprognostic (1.81e-2)" "unprognostic (8.91e-2)" "potential prognostic favorable (7.40e-6)" "unprognostic (1.21e-2)" "unprognostic (2.22e-2)" "unprognostic (4.29e-1)" "unprognostic (5.23e-2)" "unprognostic (8.33e-2)" "unprognostic (2.86e-2)" "unprognostic (7.08e-2)" "unprognostic (1.13e-2)" "unprognostic (6.67e-2)" "unprognostic (2.80e-2)" "potential prognostic unfavorable (1.47e-4)" "unprognostic (3.72e-2)" "unprognostic (6.99e-3)" "unprognostic (2.28e-2)" "unprognostic (1.92e-1)" "unprognostic (2.00e-1)" "unprognostic (8.33e-3)" "unprognostic (1.05e-2)" "unprognostic (6.55e-1)" "unprognostic (2.00e-1)" "unprognostic (1.89e-1)" "unprognostic (9.15e-2)" "unprognostic (7.15e-2)" "unprognostic (2.32e-2)" "unprognostic (1.65e-1)" "unprognostic (1.18e-1)" "unprognostic (9.59e-2)" SNRNP70 "RNPU1Z, RPU1, Snp1, SNRP70, U1-70K" ENSG00000104852 "Small nuclear ribonucleoprotein U1 subunit 70" P08621 19 49085419-49108605 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "mRNA processing" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB001718, HPA042050, HPA043516" Supported Enhanced Nucleoplasm NA NA 8300 "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 35: RS4;11 - Unknown function" "Cluster 17: Non-specific - RNA processing" 206 Nucleoplasm "CAB001718: , HPA042050: , HPA043516: " "unprognostic (3.48e-1)" "unprognostic (1.45e-2)" "unprognostic (2.06e-1)" "unprognostic (1.75e-2)" "unprognostic (2.26e-1)" "unprognostic (1.28e-1)" "unprognostic (8.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.66e-3)" "unprognostic (4.36e-2)" "unprognostic (9.04e-2)" "potential prognostic unfavorable (9.91e-4)" "unprognostic (4.17e-2)" "validated prognostic unfavorable (3.37e-4)" "validated prognostic unfavorable (4.26e-4)" "unprognostic (2.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-1)" "unprognostic (3.96e-3)" "unprognostic (1.58e-1)" "unprognostic (2.11e-3)" "unprognostic (3.08e-2)" "unprognostic (1.04e-1)" "unprognostic (6.73e-2)" "unprognostic (1.76e-1)" "unprognostic (1.86e-2)" "unprognostic (1.17e-1)" "unprognostic (1.09e-2)" "unprognostic (6.84e-2)" SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187147-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 208.0;Müller glia: 271.6;Rod photoreceptor cells: 177.2;Smooth muscle cells: 161.0" "Cell type enhanced" "Detected in many" "Glial cells: 271.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 54772596.1" "Low tissue specificity" "Detected in all" HPA001394 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Primary cilium transition zone,Centriolar satellite,Basal body" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 47: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 28 "Golgi apparatus, Plasma membrane, Centriolar satellite, Basal body" "Nucleoplasm, Primary cilium transition zone" "HPA001394: " "unprognostic (2.87e-2)" "unprognostic (4.05e-1)" "unprognostic (1.22e-1)" "unprognostic (1.48e-1)" "unprognostic (2.81e-1)" "potential prognostic unfavorable (2.33e-5)" "unprognostic (4.12e-1)" "unprognostic (1.08e-1)" "unprognostic (9.29e-2)" "unprognostic (1.14e-1)" "unprognostic (1.26e-3)" "unprognostic (1.76e-2)" "unprognostic (1.25e-1)" "unprognostic (9.13e-3)" "unprognostic (2.39e-1)" "unprognostic (5.38e-2)" "unprognostic (1.04e-1)" "unprognostic (2.79e-1)" "unprognostic (2.22e-2)" "unprognostic (1.49e-2)" "unprognostic (6.49e-3)" "unprognostic (3.10e-2)" "unprognostic (1.74e-2)" "unprognostic (6.28e-2)" "unprognostic (5.52e-2)" "unprognostic (1.38e-1)" "unprognostic (4.72e-2)" "unprognostic (7.70e-2)" "unprognostic (3.09e-1)" "unprognostic (2.10e-1)" "unprognostic (8.50e-2)" SNX10 ENSG00000086300 "Sorting nexin 10" Q9Y5X0 7 26291862-26374383 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 43.2;liver: 41.1" "Cell type enhanced" "Detected in many" "cDC: 168.5;Distal convoluted tubule cells: 363.1;Extravillous trophoblasts: 176.3;Kupffer cells: 413.0;Macrophages: 180.1;Monocyte progenitors: 186.3;monocytes: 253.0;Müller glia: 266.8;Neutrophil progenitors: 286.0;Neutrophils: 1029.3;Renal connecting tubule cells: 163.4" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 413.0;Neutrophils: 1029.3;Renal nephron cells: 363.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 181.1" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "skin cancer: 81.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Macrophages, Breast - Adipocytes (Breast), Minor Salivary Gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Microglia and Neuropil: 462673.7;Neutrophils: 1041405.4" "Tissue enriched" "Detected in single" 185 "cerebral cortex: 18535.0" "HPA015605, HPA064782" Approved Supported "Nucleoplasm,Nucleoli,Microtubules,Primary cilium,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 1: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 24: Neutrophils - Innate immunity signal integration" 6 "Nucleoplasm, Microtubules" "Nucleoli, Primary cilium, Cytosol" "HPA015605: , HPA064782: " "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (1.92e-1)" "unprognostic (1.30e-2)" "unprognostic (1.24e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (3.69e-4)" "unprognostic (2.49e-3)" "unprognostic (2.50e-2)" "unprognostic (2.24e-1)" "unprognostic (4.70e-2)" "unprognostic (2.18e-3)" "unprognostic (6.68e-2)" "unprognostic (9.83e-2)" "unprognostic (1.69e-1)" "unprognostic (3.87e-3)" "unprognostic (7.20e-2)" "unprognostic (6.01e-2)" "unprognostic (3.07e-1)" "unprognostic (1.02e-1)" "unprognostic (8.60e-3)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.62e-1)" "unprognostic (9.79e-3)" "unprognostic (2.91e-3)" "unprognostic (3.38e-1)" "unprognostic (6.47e-3)" "unprognostic (3.05e-1)" "unprognostic (1.06e-1)" "unprognostic (1.40e-1)" SNX17 KIAA0064 ENSG00000115234 "Sorting nexin 17" Q15036 2 27370496-27377535 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 204.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 26671570.7;Proximal tubules: 32358358.4" "Low tissue specificity" "Detected in all" HPA043867 Supported Enhanced Vesicles,Cytosol No No "Cluster 29: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 27: Non-specific - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 17 Vesicles Cytosol "HPA043867: " "unprognostic (7.87e-2)" "unprognostic (1.14e-2)" "unprognostic (4.19e-2)" "unprognostic (2.38e-2)" "unprognostic (2.37e-2)" "unprognostic (2.01e-1)" "unprognostic (1.39e-1)" "unprognostic (4.09e-1)" "unprognostic (2.60e-1)" "unprognostic (8.33e-3)" "potential prognostic favorable (8.93e-7)" "unprognostic (6.19e-2)" "unprognostic (9.56e-2)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (6.58e-5)" "unprognostic (1.53e-1)" "unprognostic (3.69e-3)" "unprognostic (6.59e-2)" "unprognostic (1.33e-1)" "unprognostic (3.65e-1)" "unprognostic (6.97e-2)" "unprognostic (2.94e-1)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (7.73e-2)" "unprognostic (1.45e-1)" "unprognostic (1.44e-2)" "unprognostic (1.38e-1)" "unprognostic (2.73e-1)" "unprognostic (2.57e-2)" "unprognostic (1.32e-1)" SNX7 ENSG00000162627 "Sorting nexin 7" Q9UNH6 1 98661701-98760500 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Thymic myoid cells: 194.4" "Cell type enhanced" "Detected in many" "Stromal cells: 194.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 4 "Gallbladder cancer: 209.1" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "intestine: 2314952.3;lymphoid tissue: 6104265.6;pancreas: 3126055.8;skin: 3352352.3" HPA037419 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 19: Astrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 Vesicles "Cell Junctions" "HPA037419: " "unprognostic (2.17e-1)" "unprognostic (3.21e-1)" "unprognostic (1.83e-1)" "unprognostic (1.86e-1)" "potential prognostic favorable (3.21e-4)" "unprognostic (1.18e-1)" "unprognostic (1.45e-1)" "unprognostic (7.95e-3)" "unprognostic (2.34e-1)" "unprognostic (1.13e-3)" "potential prognostic favorable (3.56e-7)" "unprognostic (6.05e-3)" "unprognostic (2.80e-1)" "validated prognostic unfavorable (2.81e-6)" "validated prognostic unfavorable (2.56e-6)" "potential prognostic unfavorable (8.50e-4)" "unprognostic (3.64e-2)" "unprognostic (1.02e-1)" "unprognostic (6.92e-3)" "unprognostic (8.99e-2)" "unprognostic (2.03e-1)" "unprognostic (5.13e-3)" "unprognostic (3.40e-1)" "unprognostic (2.79e-1)" "unprognostic (5.13e-3)" "unprognostic (3.99e-2)" "unprognostic (2.51e-1)" "unprognostic (1.81e-1)" "unprognostic (2.37e-1)" "unprognostic (3.34e-1)" "unprognostic (1.60e-1)" SNX9 "SDP1, SH3PX1, SH3PXD3A" ENSG00000130340 "Sorting nexin 9" Q9Y5X1 6 157700387-157945077 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 2921.6;Endometrial luminal cells: 2424.3;Esophageal apical cells: 1151.8" "Cell type enhanced" "Detected in all" "Glandular cells: 2921.6;Luminal cells: 2424.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.2" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA031410, HPA057203" Approved Supported "Plasma membrane,Cytosol" No No 120000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 51: Secretory epithelial cells - Mixed function" 53 "Plasma membrane" Cytosol "HPA031410: , HPA057203: " "unprognostic (4.25e-3)" "potential prognostic unfavorable (8.10e-4)" "unprognostic (5.58e-3)" "unprognostic (2.42e-3)" "unprognostic (7.14e-2)" "unprognostic (2.25e-2)" "unprognostic (9.60e-2)" "unprognostic (3.03e-3)" "unprognostic (6.28e-3)" "unprognostic (1.59e-2)" "potential prognostic favorable (3.89e-6)" "unprognostic (2.61e-3)" "unprognostic (3.97e-1)" "unprognostic (6.22e-2)" "unprognostic (2.13e-1)" "unprognostic (1.02e-3)" "unprognostic (1.77e-2)" "unprognostic (2.82e-2)" "unprognostic (1.21e-1)" "unprognostic (3.55e-3)" "unprognostic (1.07e-2)" "unprognostic (7.23e-2)" "unprognostic (9.50e-2)" "unprognostic (7.96e-2)" "unprognostic (2.05e-1)" "potential prognostic favorable (5.97e-4)" "unprognostic (7.71e-2)" "unprognostic (1.98e-1)" "unprognostic (1.98e-1)" "unprognostic (2.40e-2)" "unprognostic (1.52e-1)" SOAT1 "ACAT, ACAT1, SOAT, STAT" ENSG00000057252 "Sterol O-acyltransferase 1" P35610 1 179293714-179358680 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" "Acyltransferase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "adrenal gland: 155.9" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 897.6;monocytes: 223.9;Salivary acinar cells: 243.9" "Cell type enhanced" "Detected in all" "Adrenal endocrine cells: 897.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 178.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adrenal gland - Adrenal cortex cells, Prostate - Prostate glandular cells, Skin - Sebaceous gland cells, Testis - Leydig cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 727367.0" "Tissue enhanced" "Detected in many" "salivary gland: 2147384.3" "CAB009533, HPA047171" Enhanced Enhanced "Endoplasmic reticulum" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 36 "Endoplasmic reticulum" "CAB009533: , HPA047171: " "unprognostic (3.57e-1)" "unprognostic (3.25e-1)" "unprognostic (2.34e-1)" "unprognostic (2.63e-2)" "unprognostic (2.28e-1)" "unprognostic (4.04e-2)" "unprognostic (7.63e-2)" "unprognostic (9.93e-3)" "unprognostic (1.39e-1)" "unprognostic (4.09e-2)" "potential prognostic favorable (3.14e-4)" "unprognostic (3.23e-1)" "unprognostic (6.31e-2)" "unprognostic (7.70e-3)" "unprognostic (4.13e-3)" "unprognostic (1.20e-2)" "unprognostic (3.98e-2)" "unprognostic (4.05e-2)" "unprognostic (3.82e-3)" "unprognostic (4.48e-2)" "unprognostic (1.21e-3)" "unprognostic (3.27e-1)" "unprognostic (2.49e-1)" "unprognostic (3.59e-1)" "unprognostic (1.07e-1)" "unprognostic (2.90e-1)" "unprognostic (8.07e-2)" "unprognostic (9.52e-3)" "unprognostic (2.03e-1)" "unprognostic (9.51e-2)" "unprognostic (2.26e-1)" SOCS5 "CIS6, Cish5, CISH6, KIAA0671, SOCS-5" ENSG00000171150 "Suppressor of cytokine signaling 5" O75159 2 46698952-46780245 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Distal convoluted tubule cells: 50.2;Loop of henle epithelial cells: 45.4;Papillary tip epithelial cells: 28.6;Podocytes: 51.4;Proximal tubule cells: 39.6;Renal collecting duct intercalated cells: 40.4;Renal collecting duct principal cells: 31.9;Renal connecting tubule cells: 40.0" "Group enriched" "Detected in some" 6 "Ductal cells: 40.4;Renal nephron cells: 51.4" "Cell type enhanced" "Detected in single" "upper rhombic lip: 1.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020884, CAB025510" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 2: Neurons - Nucleosome" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" 4 Cytosol "Nucleoplasm, Plasma membrane" "CAB025510: , HPA020884: " "unprognostic (6.74e-3)" "unprognostic (2.85e-1)" "unprognostic (1.48e-1)" "unprognostic (1.56e-3)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (1.39e-1)" "unprognostic (1.23e-1)" "unprognostic (2.88e-1)" "unprognostic (4.48e-2)" "validated prognostic favorable (7.01e-5)" "validated prognostic favorable (2.02e-4)" "unprognostic (2.82e-1)" "potential prognostic unfavorable (7.78e-4)" "unprognostic (1.12e-2)" "unprognostic (8.80e-2)" "unprognostic (2.06e-3)" "unprognostic (1.85e-2)" "unprognostic (2.62e-1)" "unprognostic (7.13e-3)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (9.33e-4)" "unprognostic (1.06e-1)" "unprognostic (1.31e-1)" "unprognostic (1.88e-1)" "unprognostic (4.84e-2)" "unprognostic (8.74e-2)" "unprognostic (5.13e-2)" "unprognostic (4.63e-1)" "unprognostic (5.97e-2)" "unprognostic (1.39e-1)" SORCS2 KIAA1329 ENSG00000184985 "Sortilin related VPS10 domain containing receptor 2" Q96PQ0 4 7192538-7742836 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.6" "Cell type enhanced" "Detected in many" "Astrocytes: 211.3;Bergmann glia: 184.2;Müller glia: 202.6;Oligodendrocytes: 123.3;Renal collecting duct principal cells: 150.9;Renal connecting tubule cells: 119.8;Retinal amacrine cells: 157.3;Retinal bipolar cells: 517.8;Thyrotrophs: 166.8" "Cell type enhanced" "Detected in many" "Glial cells: 211.3;Neuronal cells: 517.8" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 430.6;eccentric medium spiny neuron: 372.5" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 19.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 16744657.0" "Group enriched" "Detected in some" "cerebral cortex: 3179588.4;intestine: 5203294.0" HPA071818 Approved Vesicles,Cytosol NA NA "Cluster 65: Brain - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Vesicles, Cytosol" "HPA071818: " "unprognostic (3.46e-2)" "unprognostic (6.83e-2)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (5.19e-2)" "unprognostic (7.59e-2)" "unprognostic (6.92e-2)" "unprognostic (3.58e-1)" "unprognostic (5.68e-2)" "unprognostic (9.31e-2)" "unprognostic (3.67e-2)" "unprognostic (2.81e-2)" "unprognostic (7.05e-3)" "unprognostic (3.30e-2)" "unprognostic (2.66e-2)" "unprognostic (3.48e-2)" "unprognostic (3.28e-2)" "unprognostic (2.86e-1)" "unprognostic (4.24e-2)" "potential prognostic unfavorable (3.57e-4)" "unprognostic (1.21e-1)" "unprognostic (9.58e-2)" "unprognostic (5.61e-2)" "unprognostic (1.67e-2)" "unprognostic (1.19e-1)" "unprognostic (2.04e-2)" "unprognostic (9.31e-3)" "unprognostic (2.42e-3)" "unprognostic (3.57e-1)" "unprognostic (1.31e-1)" "unprognostic (1.95e-1)" SORD ENSG00000140263 "Sorbitol dehydrogenase" Q00796 15 45023147-45077185 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 161.0;liver: 253.4;thyroid gland: 99.8" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 892.2;Hepatocytes: 434.7;Prostatic glandular cells: 272.5;Proximal tubule cells: 140.0;Salivary duct cells: 168.3" "Cell type enhanced" "Detected in all" "Glandular cells: 272.5;Goblet cells: 892.2;Hepatocytes: 434.7" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Liver Hepatocellular Carcinoma (TCGA): 60.8;Prostate Adenocarcinoma (TCGA): 157.6;Thyroid Carcinoma (TCGA): 73.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 11 "basophil: 87.7;eosinophil: 62.8" "Lineage enriched" "Detected in all" 12 "granulocytes: 87.7" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Breast - Breast glandular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes, Pituitary gland - Thyrotropes, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 439522678.0;Proximal tubules: 162441378.5" "Tissue enriched" "Detected in all" "liver: 2050517527.5" "HPA040260, HPA040621" Enhanced Approved "Cytosol,Acrosome,Equatorial segment" NA NA 3600000 "Cluster 22: Eosinophils - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 6 Cytosol "Acrosome, Equatorial segment" "HPA040260: , HPA040621: " "unprognostic (4.10e-2)" "unprognostic (1.82e-1)" "unprognostic (4.18e-2)" "unprognostic (1.66e-3)" "unprognostic (1.22e-1)" "unprognostic (5.03e-2)" "unprognostic (3.74e-1)" "unprognostic (1.65e-2)" "unprognostic (8.73e-3)" "unprognostic (3.61e-2)" "unprognostic (9.16e-2)" "unprognostic (4.27e-1)" "unprognostic (7.49e-3)" "unprognostic (2.24e-3)" "unprognostic (2.72e-2)" "unprognostic (4.02e-3)" "unprognostic (1.09e-2)" "potential prognostic favorable (4.76e-5)" "unprognostic (4.22e-2)" "unprognostic (8.92e-2)" "unprognostic (3.12e-1)" "unprognostic (2.51e-2)" "unprognostic (1.20e-2)" "unprognostic (2.90e-1)" "unprognostic (9.87e-2)" "unprognostic (1.57e-1)" "unprognostic (6.07e-2)" "unprognostic (5.35e-2)" "unprognostic (2.46e-2)" "unprognostic (2.83e-2)" "unprognostic (2.50e-1)" SOS1 "GF1, GINGF, HGF" ENSG00000115904 "SOS Ras/Rac guanine nucleotide exchange factor 1" Q07889 2 38962206-39124345 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Megakaryocyte progenitors: 1356.1" "Cell type enhanced" "Detected in all" "Megakaryocytes: 1356.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "blood vessel: 106682830.6" CAB005396 Uncertain Approved Cytosol NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 49: HMC-1 - Innate immune response" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 54 Cytosol "CAB005396: " "unprognostic (1.59e-2)" "unprognostic (1.46e-1)" "unprognostic (1.24e-1)" "unprognostic (1.77e-2)" "unprognostic (1.79e-1)" "unprognostic (2.61e-3)" "unprognostic (1.52e-1)" "unprognostic (1.93e-1)" "unprognostic (9.95e-2)" "unprognostic (1.27e-3)" "potential prognostic favorable (4.63e-6)" "unprognostic (4.81e-3)" "unprognostic (4.29e-2)" "unprognostic (5.62e-3)" "unprognostic (1.16e-1)" "unprognostic (1.69e-1)" "unprognostic (4.40e-2)" "unprognostic (1.01e-1)" "unprognostic (1.88e-1)" "unprognostic (1.88e-1)" "unprognostic (9.92e-2)" "unprognostic (7.01e-3)" "unprognostic (2.29e-2)" "unprognostic (1.44e-2)" "potential prognostic favorable (9.90e-4)" "unprognostic (7.52e-2)" "unprognostic (2.64e-1)" "unprognostic (6.31e-2)" "unprognostic (7.60e-2)" "unprognostic (2.47e-2)" "unprognostic (2.35e-2)" SOSTDC1 "DAND7, DKFZp564D206, USAG1" ENSG00000171243 "Sclerostin domain containing 1" Q6X4U4 7 16461481-16530580 "Predicted secreted proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 233.3" "Cell type enhanced" "Detected in some" "Breast lactating cells: 1.9;Early spermatids: 21.6;Late primary spermatocytes: 9.1;Loop of henle epithelial cells: 3.7;Proximal tubule cells: 4.1" "Cell type enriched" "Detected in some" 5 "Spermatogenic cell types: 21.6" "Low cell type specificity" "Detected in single" "Cancer enriched" "Detected in many" 7 "Kidney Renal Papillary Cell Carcinoma (TCGA): 169.4" "Region enriched" "Detected in all" 27 "choroid plexus: 247.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast myoepithelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Group enriched" "Detected in many" 5 "basal ganglia: 9.2;hippocampal formation: 18.4;pons and medulla: 15.1;thalamus: 11.9" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA042856 Uncertain "Nucleoli,Nucleoli rim,Golgi apparatus,Vesicles" "Secreted to extracellular matrix" Other NA NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 36: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 4 "Golgi apparatus" "Nucleoli, Nucleoli rim, Vesicles" "HPA042856: " "unprognostic (1.19e-1)" "unprognostic (3.42e-2)" "unprognostic (1.10e-2)" "unprognostic (7.44e-2)" "unprognostic (1.13e-1)" "unprognostic (1.73e-1)" "unprognostic (3.45e-2)" "unprognostic (3.27e-3)" "unprognostic (5.24e-2)" "unprognostic (1.42e-2)" "potential prognostic favorable (1.13e-5)" "unprognostic (7.31e-3)" "unprognostic (1.91e-2)" "unprognostic (1.53e-2)" "unprognostic (1.07e-2)" "unprognostic (9.98e-2)" "potential prognostic favorable (8.59e-4)" "unprognostic (3.78e-3)" "unprognostic (2.87e-1)" "unprognostic (2.48e-1)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (2.57e-1)" "unprognostic (6.74e-2)" "unprognostic (2.02e-2)" "unprognostic (8.34e-2)" "unprognostic (5.14e-2)" "unprognostic (1.61e-1)" "unprognostic (1.08e-1)" SOWAHC "ANKRD57, C2orf26, FLJ21870" ENSG00000198142 "Sosondowah ankyrin repeat domain family member C" Q53LP3 2 109614364-109618990 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 147.8;Esophageal apical cells: 386.1;Esophageal basal cells: 101.6;Esophageal suprabasal cells: 149.1;Ocular epithelial cells: 94.4;Suprabasal keratinocytes: 182.1;Urothelial cells: 313.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 386.1;Barrier epithelial cells: 313.1;Suprabasal cells: 182.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary gland basal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Glomeruli: 382599.2;Granulosa cells: 837812.0;Hepatocytes: 1036835.0;Keratinocytes: 945005.9;Proximal tubules: 518616.6" "Tissue enriched" "Detected in many" "blood vessel: 7603359.0" HPA056131 Enhanced Approved Cytosol No No "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 69: Urothelial cells - Basic cellular functions" 12 Cytosol "HPA056131: " "unprognostic (1.25e-1)" "unprognostic (3.20e-2)" "unprognostic (9.97e-3)" "unprognostic (2.36e-1)" "unprognostic (5.33e-1)" "unprognostic (1.55e-1)" "unprognostic (1.12e-2)" "unprognostic (1.85e-2)" "unprognostic (1.91e-1)" "potential prognostic favorable (3.08e-9)" "unprognostic (1.41e-3)" "unprognostic (2.35e-1)" "unprognostic (3.42e-3)" "potential prognostic unfavorable (3.86e-6)" "unprognostic (3.12e-2)" "unprognostic (1.86e-1)" "unprognostic (2.42e-1)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "unprognostic (1.92e-3)" "unprognostic (6.22e-3)" "unprognostic (5.68e-2)" "unprognostic (1.65e-2)" "unprognostic (3.75e-2)" "unprognostic (2.28e-2)" "unprognostic (1.27e-1)" "unprognostic (2.08e-1)" "unprognostic (8.53e-2)" "unprognostic (1.41e-2)" SOX10 "DOM, SOX-10, WS2E, WS4" ENSG00000100146 "SRY-box transcription factor 10" P56693 22 37970686-37987422 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Deafness, Disease variant, Hirschsprung disease, Kallmann syndrome, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 151.8;salivary gland: 105.2" "Group enriched" "Detected in many" 6 "Breast lactating cells: 86.8;Breast myoepithelial cells: 56.8;Breast secretory cells: 63.9;Lacrimal acinar cells: 96.0;Melanocytes: 167.7;Oligodendrocyte progenitor cells: 130.3;Oligodendrocytes: 134.7;Salivary acinar cells: 76.1;Salivary myoepithelial cells: 50.1;Schwann cells: 183.6" "Group enriched" "Detected in many" 9 "Acinar cells: 96.0;Glial cells: 183.6;Pigment cells: 167.7;Secretory cells: 86.8;Secretory gland support: 56.8" "Group enriched" "Detected in many" 59 "committed oligodendrocyte precursor: 230.6;oligodendrocyte: 122.4;oligodendrocyte precursor cell: 143.8" "Cancer enriched" "Detected in many" 9 "Skin Cutaneous Melanoma (TCGA): 542.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 16 "skin cancer: 313.1" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 3437 "salivary gland: 343661.9" "CAB003171, HPA068898" Enhanced Supported Nucleoplasm Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 20 Nucleoplasm "CAB003171: , HPA068898: " "unprognostic (3.46e-3)" "unprognostic (2.43e-1)" "unprognostic (1.47e-1)" "unprognostic (9.51e-2)" "unprognostic (1.14e-1)" "unprognostic (8.32e-2)" "unprognostic (2.90e-1)" "unprognostic (1.73e-2)" "unprognostic (7.51e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (2.39e-1)" SOX11 ENSG00000176887 "SRY-box transcription factor 11" P35716 2 5692384-5701385 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "brain: 2.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 4.6;Brain inhibitory neurons: 15.4;Breast myoepithelial cells: 10.3;Breast secretory cells: 11.7;Ependymal cells: 7.3;Myosatellite cells: 4.7;Oligodendrocyte progenitor cells: 15.6;Other brain neurons: 18.5;Retinal amacrine cells: 4.6;Retinal ganglion cells: 3.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 7.3;Glial cells: 15.6;Neuronal cells: 18.5;Secretory cells: 11.7;Secretory gland support: 10.3" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 40.2" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 13.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Bone cancer: 12.9;Neuroblastoma: 48.4" "Skeletal muscle - Fibroblasts, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000448, HPA000536, CAB056152, CAB056153" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 1 Nucleoplasm "Plasma membrane" "CAB056152: , CAB056153: , HPA000448: , HPA000536: " "unprognostic (2.81e-2)" "unprognostic (5.59e-2)" "unprognostic (2.83e-1)" "unprognostic (8.61e-3)" "unprognostic (7.25e-3)" "unprognostic (1.39e-1)" "unprognostic (2.28e-2)" "unprognostic (3.75e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "unprognostic (1.05e-2)" SOX12 SOX22 ENSG00000177732 "SRY-box transcription factor 12" O15370 20 325552-330224 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal bipolar cells: 33.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055052, HPA061627" Enhanced Nucleoplasm No No "Cluster 64: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Nucleoplasm "HPA055052: , HPA061627: " "unprognostic (6.61e-2)" "unprognostic (1.08e-1)" "unprognostic (4.00e-1)" "unprognostic (1.62e-2)" "unprognostic (2.02e-3)" "unprognostic (1.12e-2)" "unprognostic (1.88e-3)" "unprognostic (5.08e-2)" "unprognostic (1.76e-1)" "unprognostic (1.90e-1)" "potential prognostic unfavorable (8.82e-8)" "unprognostic (1.03e-2)" "unprognostic (7.33e-2)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (3.70e-6)" "unprognostic (6.08e-2)" "unprognostic (2.95e-1)" "unprognostic (9.90e-2)" "unprognostic (4.13e-3)" "unprognostic (1.60e-1)" "unprognostic (1.05e-1)" "unprognostic (5.38e-3)" "unprognostic (4.20e-2)" "unprognostic (2.84e-2)" "unprognostic (1.71e-1)" "unprognostic (5.91e-2)" "unprognostic (7.95e-2)" "unprognostic (1.61e-2)" "unprognostic (2.18e-1)" "unprognostic (2.48e-2)" "unprognostic (6.03e-2)" SOX15 "SOX20, SOX26, SOX27" ENSG00000129194 "SRY-box transcription factor 15" O60248 17 7588178-7590094 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 85.9;skin 1: 48.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 188.2;Epididymal basal cells: 58.3;Esophageal apical cells: 238.9;Esophageal basal cells: 203.3;Esophageal suprabasal cells: 205.6;Ocular epithelial cells: 193.6;Suprabasal keratinocytes: 163.2" "Group enriched" "Detected in many" 5 "Apical squamous epithelial cells: 238.9;Barrier epithelial cells: 193.6;Basal cells: 203.3;Suprabasal cells: 205.6" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 77.8;Testicular Germ Cell Tumor (TCGA): 129.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 6.7;non-classical monocyte: 10.6" "Lineage enriched" "Detected in many" 5 "monocytes: 10.6" "Cancer enhanced" "Detected in all" "cervical cancer: 73.6;Esophageal cancer: 53.2;head and neck cancer: 82.2" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Keratinocyte (other), Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 4381 "Keratinocytes: 438119.0" "Not detected" "Not detected" "HPA067196, HPA074049" Enhanced Approved Nucleoplasm,Nucleoli,Vesicles Yes NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 26 Nucleoplasm "Nucleoli, Vesicles" "HPA067196: , HPA074049: " "unprognostic (9.76e-2)" "unprognostic (2.02e-2)" "unprognostic (4.65e-3)" "unprognostic (3.57e-1)" "unprognostic (2.75e-2)" "unprognostic (4.44e-2)" "unprognostic (3.03e-1)" "unprognostic (2.07e-1)" "unprognostic (6.67e-2)" "unprognostic (6.75e-2)" "unprognostic (1.61e-3)" "unprognostic (1.33e-1)" "unprognostic (1.76e-2)" "unprognostic (5.59e-2)" "unprognostic (5.93e-2)" "potential prognostic favorable (8.00e-4)" "unprognostic (9.45e-2)" "unprognostic (2.43e-1)" "unprognostic (1.41e-1)" "unprognostic (1.25e-1)" "unprognostic (3.67e-1)" "unprognostic (1.14e-1)" "unprognostic (1.77e-1)" "unprognostic (3.51e-3)" "unprognostic (6.29e-2)" SOX18 ENSG00000203883 "SRY-box transcription factor 18" P35713 20 64047582-64049639 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Hypotrichosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 77.1" "Group enriched" "Detected in some" 14 "Late primary spermatocytes: 78.0;Lymphatic endothelial cells: 120.4;Vascular endothelial cells: 268.4" "Group enriched" "Detected in many" 16 "Endothelial cells: 268.4;Spermatogenic cell types: 78.0" "Cell type enriched" "Detected in some" 10 "endothelial cell: 248.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 10.9" "Breast - Endothelial cells, Colon - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells, Prostate - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Keratinocytes: 2261681.6" "Not detected" "Not detected" HPA073703 Approved Nucleoplasm NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Nucleoplasm "HPA073703: " "unprognostic (5.80e-2)" "unprognostic (2.27e-1)" "unprognostic (3.10e-2)" "unprognostic (2.68e-1)" "unprognostic (2.34e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-2)" "unprognostic (1.05e-1)" "unprognostic (2.30e-2)" "unprognostic (1.26e-2)" "unprognostic (3.22e-3)" "unprognostic (1.90e-3)" "potential prognostic unfavorable (6.23e-4)" "unprognostic (7.27e-2)" "unprognostic (9.97e-3)" "unprognostic (4.48e-2)" "unprognostic (8.78e-3)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (1.73e-3)" "unprognostic (2.10e-1)" "unprognostic (9.36e-2)" "unprognostic (1.45e-3)" "unprognostic (2.48e-1)" "unprognostic (2.06e-1)" "unprognostic (9.69e-3)" "unprognostic (2.07e-1)" "unprognostic (1.41e-1)" "unprognostic (5.24e-2)" SOX3 PHP ENSG00000134595 "SRY-box transcription factor 3" P41225 X 140502985-140505069 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.3;fallopian tube: 8.7;testis: 2.2" "Group enriched" "Detected in some" 4 "Fallopian secretory cells: 38.4;Fallopian tube ciliated cells: 35.2;Oocytes: 18.4" "Group enriched" "Detected in some" 4 "Ciliated cells: 35.2;Oocytes: 18.4;Secretory cells: 38.4" "Cell type enriched" "Detected in some" 9 "oligodendrocyte precursor cell: 10.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.3" "Region enriched" "Detected in many" 5 "hypothalamus: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Brain cancer: 8.8;testis cancer: 3.1" "Pituitary gland - Gonadotropes" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 2527 "Fallopian tube cells: 252663.1" "Tissue enriched" "Detected in single" 45378 "fallopian tube: 4537812.3" "HPA054720, HPA075003" Enhanced Nucleoplasm NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 72: Neuronal - Signal transduction" "Cluster 11: Muller glia cells - Retinal homeostasis" 3 Nucleoplasm "HPA054720: , HPA075003: " "unprognostic (2.31e-1)" "unprognostic (5.08e-2)" "potential prognostic favorable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" SOX5 "L-SOX5, MGC35153" ENSG00000134532 "SRY-box transcription factor 5" P35711 12 23529504-24562544 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 29.2" "Cell type enhanced" "Detected in many" "Adipocytes: 4038.1;Astrocytes: 2417.9;Bergmann glia: 2542.8;Endometrial stromal cells: 2054.4;Ependymal cells: 1989.1;Fibro-adipogenic progenitors: 1444.9;Melanocytes: 1416.3;Oligodendrocyte progenitor cells: 2091.0;Pituicytes/FSCs: 1319.5;Renal collecting duct principal cells: 1356.4;Retinal ganglion cells: 1437.0;Vascular smooth muscle cells: 1533.9" "Cell type enhanced" "Detected in many" "Adipocytes: 4038.1;Glial cells: 2542.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 8.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 1.4;naive B-cell: 1.3" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cancer enhanced" "Detected in many" "skin cancer: 14.5" "Kidney - Fibroblasts, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 2220369.5" "Tissue enriched" "Detected in single" 20521 "bone marrow: 2052089.0" HPA060499 Supported Nucleoplasm NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 47: Testis - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 69: Skin cancer - ECM organization" "Cluster 89: Adipocytes - Lipid metabolism" 34 Nucleoplasm "HPA060499: " "unprognostic (1.12e-2)" "unprognostic (1.61e-1)" "unprognostic (3.52e-2)" "unprognostic (4.31e-1)" "unprognostic (2.73e-1)" "unprognostic (1.35e-1)" "unprognostic (3.64e-2)" "unprognostic (1.26e-3)" "unprognostic (3.08e-2)" "unprognostic (2.18e-1)" "unprognostic (2.22e-1)" "unprognostic (1.95e-3)" "unprognostic (2.70e-3)" "unprognostic (1.90e-1)" "unprognostic (4.03e-1)" "unprognostic (4.13e-2)" "unprognostic (1.09e-2)" "unprognostic (6.96e-2)" "unprognostic (3.06e-2)" "unprognostic (1.84e-2)" "unprognostic (1.97e-1)" "unprognostic (3.24e-1)" SOX8 ENSG00000005513 "SRY-box transcription factor 8" P57073 16 981770-986979 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 92.6" "Group enriched" "Detected in some" 5 "Müller glia: 156.6;Oligodendrocyte progenitor cells: 161.8;Oligodendrocytes: 111.7" "Cell type enriched" "Detected in many" 9 "Glial cells: 161.8" "Group enriched" "Detected in many" 8 "committed oligodendrocyte precursor: 225.9;oligodendrocyte: 85.8;oligodendrocyte precursor cell: 185.8" "Cancer enriched" "Detected in many" 7 "Glioblastoma Multiforme (TCGA): 104.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "Rhabdoid: 9.3;Sarcoma: 29.1;skin cancer: 8.1" "Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Skin - Eccrine sweat gland cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041640, HPA058665" Enhanced Nucleoplasm No NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 14: Oligodendrocyte progenitor cells - Development & myelination" Nucleoplasm "HPA041640: , HPA058665: " "unprognostic (1.95e-2)" "unprognostic (5.79e-2)" "unprognostic (1.74e-2)" "unprognostic (9.93e-2)" "unprognostic (4.86e-2)" "potential prognostic favorable (4.62e-4)" "potential prognostic favorable (7.47e-4)" "unprognostic (2.07e-1)" "unprognostic (3.95e-1)" "unprognostic (9.55e-3)" "unprognostic (8.06e-2)" "unprognostic (2.24e-1)" "unprognostic (1.58e-2)" "unprognostic (6.21e-2)" "unprognostic (6.61e-2)" "unprognostic (1.18e-1)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" SOX9 "CMD1, CMPD1, SRA1" ENSG00000125398 "SRY-box transcription factor 9" P48436 17 72121020-72126416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 75.5" "Cell type enhanced" "Detected in many" "Breast lactating cells: 225.4;Breast secretory cells: 261.8;Ependymal cells: 223.1;Epididymal efferent duct absorptive cells: 349.0;Gastric progenitor cells: 205.1;Lacrimal acinar cells: 270.8;Mucous neck cells: 336.9;Pancreatic duct cells: 203.3;Parietal cells: 219.2;Prostatic club cells: 229.5;Retinal pigment epithelial cells: 234.5;Salivary ionocytes: 231.6;Tuft cells: 219.0" "Cell type enhanced" "Detected in many" "Ductal cells: 349.0;Gastric glandular cells: 336.9" "Cell type enhanced" "Detected in many" "astrocyte: 193.5;ependymal cell: 258.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Cholangiocytes, Pituitary gland - Undifferentiated cells (Pituitary gland), Prostate - Prostate basal glandular cells, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "intestine: 30921714.1" "HPA001758, CAB022456, CAB068240, HPA070776" Enhanced Enhanced Nucleoplasm NA NA "Cluster 36: Brain & Liver - Signaling" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 16 Nucleoplasm "CAB022456: , CAB068240: , HPA001758: , HPA070776: " "unprognostic (2.34e-1)" "unprognostic (4.16e-2)" "unprognostic (5.80e-2)" "unprognostic (2.29e-3)" "unprognostic (1.17e-2)" "unprognostic (1.29e-1)" "unprognostic (1.34e-1)" "unprognostic (3.97e-3)" "unprognostic (7.66e-3)" "unprognostic (1.50e-1)" "unprognostic (2.39e-3)" "unprognostic (1.22e-2)" "unprognostic (5.23e-2)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (2.63e-2)" "unprognostic (2.88e-3)" "unprognostic (4.21e-2)" "unprognostic (1.83e-2)" "unprognostic (2.77e-1)" "unprognostic (9.92e-2)" "unprognostic (8.70e-2)" "unprognostic (1.57e-2)" "unprognostic (2.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-1)" "unprognostic (4.58e-2)" "unprognostic (2.63e-2)" "unprognostic (9.80e-2)" "unprognostic (7.50e-2)" "unprognostic (1.12e-1)" SP110 "IFI41, IFI75" ENSG00000135899 "SP110 nuclear body protein" Q9HB58 2 230165186-230225729 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 374.8;Breast lactating cells: 238.0;Neutrophils: 538.7;pDCs: 239.6" "Cell type enhanced" "Detected in all" "B-cells: 374.8;Neutrophils: 538.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 212.3;leukocyte: 164.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Endothelial cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 5705293.8;T-cells: 3825435.6" "Group enriched" "Detected in some" 15896 "lymphoid tissue: 1066301.6;ovary: 2112856.2" HPA058554 Supported Nucleoplasm No No "Cluster 20: Non-specific - DNA binding" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 7 Nucleoplasm "HPA058554: " "unprognostic (6.79e-3)" "unprognostic (1.66e-1)" "unprognostic (1.07e-1)" "unprognostic (3.73e-2)" "unprognostic (7.33e-2)" "unprognostic (3.17e-2)" "unprognostic (4.17e-2)" "unprognostic (5.15e-2)" "unprognostic (3.16e-2)" "unprognostic (1.52e-1)" "unprognostic (3.22e-2)" "unprognostic (1.05e-1)" "unprognostic (7.09e-3)" "unprognostic (6.45e-3)" "unprognostic (1.91e-2)" "unprognostic (1.27e-2)" "unprognostic (4.50e-2)" "unprognostic (1.57e-1)" "unprognostic (2.05e-1)" "unprognostic (2.98e-2)" "unprognostic (2.19e-1)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (4.45e-3)" "unprognostic (4.31e-1)" "unprognostic (8.23e-2)" "unprognostic (3.34e-3)" "unprognostic (3.43e-1)" "unprognostic (1.94e-1)" "unprognostic (5.95e-2)" "unprognostic (1.77e-2)" "unprognostic (4.97e-2)" SP3 SPR-2 ENSG00000172845 "Sp3 transcription factor" Q02447 2 173880850-173965373 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 449.6;Neutrophils: 919.6" "Cell type enhanced" "Detected in all" "Neutrophils: 919.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 3205512.8;Glomeruli: 2793425.6" "Tissue enriched" "Detected in many" "lung: 3326522.8" "CAB004580, HPA032145, HPA032146" Supported Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 4: Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 23 Nucleoplasm Cytosol "CAB004580: , HPA032145: , HPA032146: " "unprognostic (8.08e-2)" "unprognostic (1.83e-1)" "unprognostic (1.68e-1)" "unprognostic (1.90e-1)" "unprognostic (3.04e-1)" "unprognostic (8.68e-2)" "unprognostic (2.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.65e-2)" "unprognostic (2.76e-2)" "potential prognostic favorable (1.70e-5)" "unprognostic (6.42e-2)" "unprognostic (3.81e-3)" "unprognostic (9.15e-3)" "unprognostic (4.55e-2)" "unprognostic (1.34e-2)" "unprognostic (2.19e-2)" "unprognostic (5.08e-2)" "unprognostic (3.28e-2)" "unprognostic (1.70e-1)" "unprognostic (1.70e-3)" "unprognostic (5.76e-3)" "unprognostic (5.59e-2)" "unprognostic (2.22e-1)" "unprognostic (4.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-2)" "unprognostic (2.43e-1)" "unprognostic (1.94e-1)" "unprognostic (3.65e-2)" "unprognostic (3.66e-2)" SP6 "Epfn, KLF14" ENSG00000189120 "Sp6 transcription factor" Q3SY56 17 47844908-47855874 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 21.4;skin 1: 13.9" "Cell type enhanced" "Detected in some" "Breast lactating cells: 25.3;Cytotrophoblasts: 70.2;Enterocytes: 14.1;Esophageal apical cells: 37.3;Migrating cytotrophoblasts: 34.6;Prostatic hillock cells: 13.7;Syncytiotrophoblasts: 108.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 37.3;Secretory cells: 25.3;Trophoblast cells: 108.3" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 18.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "cervical cancer: 33.9;colorectal cancer: 22.5" "Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA024516, HPA044469" Supported "Nucleoplasm,Mitotic spindle,Centrosome" Yes No "Cluster 11: Esophagus - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 19 Nucleoplasm "Mitotic spindle, Centrosome" "HPA024516: , HPA044469: " "unprognostic (2.09e-1)" "unprognostic (5.92e-3)" "unprognostic (4.11e-2)" "unprognostic (7.43e-2)" "unprognostic (1.70e-2)" "unprognostic (1.89e-3)" "unprognostic (2.34e-2)" "potential prognostic unfavorable (7.08e-4)" "unprognostic (2.01e-1)" "unprognostic (4.91e-1)" "unprognostic (1.50e-2)" "potential prognostic unfavorable (1.83e-5)" "unprognostic (3.57e-1)" "unprognostic (3.06e-3)" "unprognostic (1.66e-1)" "unprognostic (5.65e-2)" "unprognostic (4.85e-3)" "unprognostic (8.09e-3)" "unprognostic (5.20e-3)" "unprognostic (1.79e-1)" "unprognostic (3.09e-2)" "unprognostic (1.61e-1)" "unprognostic (1.02e-1)" "potential prognostic favorable (3.30e-4)" "unprognostic (2.16e-1)" "unprognostic (6.41e-2)" SPA17 "CT22, SP17" ENSG00000064199 "Sperm autoantigenic protein 17" Q15506 11 124673844-124697518 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 23.1;testis: 36.7" "Group enriched" "Detected in many" 4 "Early spermatids: 1487.2;Late primary spermatocytes: 1868.7;Late spermatids: 3590.4" "Cell type enriched" "Detected in many" 6 "Spermatogenic cell types: 3590.4" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 36.6;ependymal cell: 119.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 15952819.6" "Tissue enriched" "Detected in some" "fallopian tube: 4140878.7" HPA037568 Enhanced Approved "Golgi apparatus,Vesicles,Principal piece" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 13 "Golgi apparatus, Principal piece" Vesicles "HPA037568: " "unprognostic (6.03e-2)" "unprognostic (9.37e-2)" "unprognostic (1.16e-1)" "unprognostic (1.75e-1)" "potential prognostic favorable (5.52e-4)" "unprognostic (1.04e-2)" "unprognostic (2.77e-1)" "unprognostic (5.94e-3)" "unprognostic (6.12e-2)" "potential prognostic favorable (5.53e-5)" "unprognostic (2.84e-2)" "unprognostic (4.98e-3)" "unprognostic (4.96e-2)" "unprognostic (7.32e-2)" "unprognostic (7.58e-2)" "unprognostic (1.88e-1)" "unprognostic (1.23e-1)" "unprognostic (8.29e-2)" "unprognostic (1.46e-1)" "unprognostic (1.74e-1)" "unprognostic (1.04e-1)" "unprognostic (5.23e-2)" "unprognostic (6.08e-2)" "unprognostic (1.78e-1)" "unprognostic (2.42e-1)" "unprognostic (2.04e-1)" "unprognostic (1.56e-2)" "unprognostic (1.31e-1)" "unprognostic (1.91e-2)" SPACA4 SAMP14 ENSG00000177202 "Sperm acrosome associated 4" Q8TDM5 19 48606742-48607714 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 111.8" "Group enriched" "Detected in some" 4 "Early spermatids: 1273.7;Late primary spermatocytes: 404.8" "Cell type enriched" "Detected in some" 301 "Spermatogenic cell types: 1273.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "colorectal cancer: 1.3" "Colon - Colon enterocytes, Prostate - Urothelial cells, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041927, HPA061302" Enhanced Enhanced Acrosome NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Acrosome "HPA041927: , HPA061302: " "unprognostic (2.69e-1)" "potential prognostic favorable (4.57e-4)" "unprognostic (2.35e-1)" "unprognostic (7.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.62e-1)" "unprognostic (1.01e-1)" "unprognostic (9.87e-3)" "unprognostic (5.04e-1)" SPACA7 C13orf28 ENSG00000153498 "Sperm acrosome associated 7" Q96KW9 13 112376355-112434689 "Predicted intracellular proteins, Predicted secreted proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 161 "testis: 83.8" "Group enriched" "Detected in some" 301 "Early spermatids: 1322.6;Late primary spermatocytes: 553.2;Late spermatids: 934.7" "Cell type enriched" "Detected in some" 426 "Spermatogenic cell types: 1322.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048349 Enhanced Approved "Microtubules,Mitochondria,Acrosome,Equatorial segment,Principal piece,End piece" "Secreted in male reproductive system" Other NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 79: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Microtubules, Acrosome" "Mitochondria, Equatorial segment, Principal piece, End piece" "HPA048349: " SPACA9 "C9orf9, Mast" ENSG00000165698 "Sperm acrosome associated 9" Q96E40 9 132878027-132890201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 69.8;fallopian tube: 36.8;testis: 124.6" "Group enriched" "Detected in many" 4 "Early spermatids: 2418.5;Late spermatids: 2904.4" "Cell type enriched" "Detected in many" 11 "Spermatogenic cell types: 2904.4" "Cell type enhanced" "Detected in all" "ependymal cell: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Prostate - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 278709 "Fallopian tube cells: 27870881.5" "Tissue enriched" "Detected in some" "fallopian tube: 9541891.0" "HPA022243, HPA051600" Enhanced Supported "Vesicles,Cytosol,End piece" NA No "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 70: DU4475 - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 9 Vesicles "Cytosol, End piece" "HPA022243: , HPA051600: " "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" "unprognostic (2.18e-2)" "unprognostic (3.99e-3)" "unprognostic (6.93e-3)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (9.48e-2)" "unprognostic (1.28e-1)" "unprognostic (2.94e-3)" "unprognostic (4.68e-2)" "unprognostic (1.17e-2)" "unprognostic (1.43e-3)" "unprognostic (6.16e-2)" "unprognostic (3.10e-1)" "unprognostic (3.08e-2)" "unprognostic (9.48e-2)" "unprognostic (3.24e-1)" "unprognostic (5.48e-2)" "unprognostic (1.51e-1)" "unprognostic (9.40e-2)" "unprognostic (5.84e-2)" "unprognostic (4.85e-2)" "unprognostic (1.42e-2)" "unprognostic (7.61e-2)" "unprognostic (1.98e-1)" "unprognostic (2.43e-2)" "unprognostic (8.34e-2)" "unprognostic (1.37e-3)" SPAG16 "DKFZp666P1710, FLJ22724, PF20, WDR29" ENSG00000144451 "Sperm associated antigen 16" Q8N0X2 2 213284389-214410501 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 799.1;Endometrial ciliated cells: 815.8;Ependymal cells: 1818.4;Fallopian tube ciliated cells: 867.9;Lactotrophs: 1280.6;Respiratory ciliated cells: 1623.0;Somatotrophs: 1585.4;Thyrotrophs: 2509.2" "Cell type enhanced" "Detected in all" "Ciliated cells: 1818.4;Pituitary endocrine cells: 2509.2" "Cell type enhanced" "Detected in all" "ependymal cell: 1980.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 674 "Fallopian tube cells: 67373.7" "Not detected" "Not detected" HPA037542 Approved Approved "Vesicles,Plasma membrane,Cytosol,Acrosome,Equatorial segment" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 39: Astrocytes - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" "Cytosol, Equatorial segment" "Vesicles, Plasma membrane, Acrosome" "HPA037542: " "unprognostic (1.91e-1)" "unprognostic (5.21e-3)" "unprognostic (5.51e-2)" "unprognostic (4.79e-2)" "unprognostic (1.40e-2)" "unprognostic (5.63e-2)" "unprognostic (1.72e-1)" "unprognostic (5.98e-2)" "unprognostic (1.51e-1)" "unprognostic (2.07e-1)" "potential prognostic favorable (1.06e-5)" "unprognostic (3.22e-2)" "unprognostic (2.07e-1)" "unprognostic (2.10e-2)" "unprognostic (1.45e-2)" "unprognostic (3.17e-1)" "unprognostic (5.20e-2)" "unprognostic (2.79e-1)" "unprognostic (5.03e-1)" "unprognostic (2.73e-1)" "unprognostic (2.04e-1)" "unprognostic (1.03e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (3.51e-4)" "unprognostic (3.35e-2)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (7.21e-3)" "unprognostic (8.25e-2)" "unprognostic (1.32e-1)" "unprognostic (6.03e-2)" SPAG17 "CT143, FLJ34497, PF6, RP4-776P7.2" ENSG00000155761 "Sperm associated antigen 17" Q6Q759 1 117953590-118185228 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 25.7;testis: 14.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 722.0;Early spermatids: 285.2;Endometrial ciliated cells: 874.0;Ependymal cells: 1673.1;Epididymal efferent duct ciliated cells: 675.3;Fallopian tube ciliated cells: 683.9;Late primary spermatocytes: 257.9;Late spermatids: 648.3;Respiratory ciliated cells: 1267.8" "Group enriched" "Detected in many" 8 "Ciliated cells: 1673.1;Spermatogenic cell types: 648.3" "Group enriched" "Detected in all" 17 "choroid plexus epithelial cell: 606.0;ependymal cell: 1720.2" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "choroid plexus: 56.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Rhabdoid: 1.3" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 14.2" "Group enriched" "Detected in some" 30243 "Alveolar cell types: 4461736.8;Fallopian tube cells: 1586831.1" "Tissue enriched" "Detected in single" 27776 "fallopian tube: 2777588.5" "HPA028597, HPA028666" Enhanced Approved "Equatorial segment,Mid piece,Principal piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 15: Kidney cancer - Membrane components" "Cluster 34: Ciliated cells - Cilia assembly & function" 2 "Mid piece, Principal piece" "Equatorial segment" "HPA028597: , HPA028666: " "unprognostic (3.14e-2)" "unprognostic (3.76e-2)" "unprognostic (1.70e-1)" "unprognostic (4.73e-3)" "potential prognostic unfavorable (2.90e-5)" "unprognostic (8.17e-2)" "potential prognostic unfavorable (3.40e-4)" "unprognostic (5.30e-2)" "unprognostic (3.85e-3)" "potential prognostic unfavorable (4.60e-5)" "unprognostic (2.08e-2)" "unprognostic (8.09e-2)" "unprognostic (3.07e-1)" "unprognostic (1.41e-1)" "unprognostic (2.23e-2)" "unprognostic (7.94e-3)" "unprognostic (2.73e-2)" SPAG5 "DEEPEST, hMAP126, MAP126" ENSG00000076382 "Sperm associated antigen 5" Q96R06 17 28577565-28599025 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 35.7;kidney: 37.6;testis: 72.1" "Group enriched" "Detected in many" 4 "Early spermatids: 121.1;Late primary spermatocytes: 164.0" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 164.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 11.7;T-reg: 5.0" "Group enriched" "Detected in many" 6 "granulocytes: 11.7;T-cells: 5.0" "Low cancer specificity" "Detected in all" "Heart muscle - Mitotic cells (Heart), Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 10651 "Granulosa cells: 823540.3;Oocytes: 1306751.7" "Tissue enriched" "Detected in single" 112 "bone marrow: 11153.1" "HPA022008, HPA022479, HPA024418" Approved Supported "Nuclear bodies,Mitotic spindle,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 39: Testis - Nuclear processes" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 63 "Nuclear bodies, Mitotic spindle" Cytosol "HPA022008: , HPA022479: , HPA024418: " "unprognostic (1.54e-2)" "unprognostic (1.18e-2)" "unprognostic (2.73e-1)" "unprognostic (2.03e-2)" "unprognostic (1.41e-2)" "unprognostic (1.41e-1)" "unprognostic (2.14e-1)" "unprognostic (7.67e-3)" "unprognostic (1.29e-1)" "potential prognostic unfavorable (3.19e-5)" "unprognostic (9.81e-3)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (1.76e-4)" "validated prognostic unfavorable (2.12e-5)" "validated prognostic unfavorable (8.67e-7)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (2.54e-2)" "unprognostic (6.48e-2)" "unprognostic (1.68e-3)" "unprognostic (1.32e-1)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (7.56e-4)" "unprognostic (1.12e-2)" "unprognostic (3.71e-2)" "unprognostic (5.91e-2)" "unprognostic (2.52e-2)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (1.89e-1)" "unprognostic (1.54e-2)" "unprognostic (4.43e-2)" SPAG6 "CFAP194, CT141, FAP194, PF16, Repro-SA-1" ENSG00000077327 "Sperm associated antigen 6" O75602 10 22345445-22454224 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "choroid plexus: 94.1;fallopian tube: 46.1;testis: 90.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 181.0;Early primary spermatocytes: 430.2;Early spermatids: 156.1;Endometrial ciliated cells: 119.2;Ependymal cells: 335.3;Epididymal efferent duct ciliated cells: 304.3;Fallopian tube ciliated cells: 307.0;Late primary spermatocytes: 801.2;Respiratory ciliated cells: 361.5" "Group enriched" "Detected in many" 6 "Ciliated cells: 361.5;Spermatogenic cell types: 801.2" "Group enriched" "Detected in all" 21 "choroid plexus epithelial cell: 187.3;ependymal cell: 429.4" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 5.9" "Region enhanced" "Detected in all" "choroid plexus: 133.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Leukemia: 7.4;Myeloma: 6.8;Rhabdoid: 4.6" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Region enhanced" "Detected in many" "midbrain: 14.7" "Cell type enriched" "Detected in single" 704698 "Fallopian tube cells: 70469763.1" "Tissue enriched" "Detected in single" 294635 "fallopian tube: 29463521.8" HPA038440 Enhanced Supported "Calyx,Mid piece,Principal piece,End piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 65: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" "Calyx, Mid piece, Principal piece, End piece" "HPA038440: " "unprognostic (1.66e-1)" "unprognostic (2.02e-3)" "unprognostic (1.83e-3)" "unprognostic (4.42e-2)" "unprognostic (1.12e-1)" "unprognostic (1.46e-1)" "unprognostic (2.15e-1)" "unprognostic (2.69e-2)" "unprognostic (2.43e-1)" "unprognostic (3.28e-1)" "unprognostic (3.09e-2)" "unprognostic (2.14e-1)" "unprognostic (1.03e-2)" SPAG8 "BS-84, CT142, HSD-1, hSMP-1, SPAG3" ENSG00000137098 "Sperm associated antigen 8" Q99932 9 35808045-35812272 "Predicted intracellular proteins" "Cell cycle, Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 10.7;fallopian tube: 13.4;testis: 8.2" "Group enriched" "Detected in many" 4 "Choroid plexus epithelial cells: 102.9;Endometrial ciliated cells: 101.0;Ependymal cells: 323.4;Epididymal efferent duct ciliated cells: 133.0;Fallopian tube ciliated cells: 180.9;Late primary spermatocytes: 137.8;Respiratory ciliated cells: 172.3" "Group enriched" "Detected in many" 13 "Ciliated cells: 323.4;Spermatogenic cell types: 137.8" "Group enriched" "Detected in all" 15 "choroid plexus epithelial cell: 166.8;ependymal cell: 346.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "choroid plexus: 33.4" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 23687 "Fallopian tube cells: 2368730.9" "Tissue enriched" "Detected in single" 36563 "fallopian tube: 3656325.0" HPA068012 Enhanced Supported "Nucleoplasm,Primary cilium,Cytosol,Acrosome,Equatorial segment,Principal piece,End piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 4 "Primary cilium, Acrosome, Equatorial segment, End piece" "Nucleoplasm, Cytosol, Principal piece" "HPA068012: " "unprognostic (1.51e-1)" "unprognostic (1.96e-1)" "unprognostic (1.42e-1)" "unprognostic (2.76e-2)" "unprognostic (1.11e-3)" "unprognostic (1.32e-1)" "unprognostic (1.20e-2)" "unprognostic (8.42e-2)" SPANXN4 "CT11.9, SPANX-N4" ENSG00000189326 "SPANX family member N4" Q5MJ08 X 143025928-143034702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 249 "testis: 24.8" "Group enriched" "Detected in some" 8 "Early spermatids: 94.3;Late spermatids: 366.3" "Cell type enriched" "Detected in some" 129 "Spermatogenic cell types: 366.3" "Cell type enhanced" "Detected in single" "hippocampal dentate gyrus: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045730, HPA059094" Uncertain Uncertain "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 47: Leukemia - Hemostasis" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Vesicles, Plasma membrane" "Nuclear membrane" "HPA045730: , HPA059094: " SPATA12 ENSG00000186451 "Spermatogenesis associated 12" Q7Z6I5 3 57060664-57075432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 57 "testis: 21.4" "Group enriched" "Detected in many" 39 "Early spermatids: 677.7;Late spermatids: 1849.0" "Cell type enriched" "Detected in many" 105 "Spermatogenic cell types: 1849.0" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 7.2;endothelial cell: 3.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043323, HPA075578" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 23: Testis - Spermatogenesis" "Cluster 8: Immune cells - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 22 "Nucleoplasm, Cytosol" "Plasma membrane" "HPA043323: , HPA075578: " "unprognostic (2.74e-1)" "unprognostic (3.22e-2)" "unprognostic (1.78e-2)" "unprognostic (3.98e-2)" SPATA18 FLJ32906 ENSG00000163071 "Spermatogenesis associated 18" Q8TC71 4 52051304-52097299 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 64.3;testis: 27.5" "Cell type enriched" "Detected in many" 5 "Late spermatids: 3633.7" "Cell type enriched" "Detected in many" 8 "Spermatogenic cell types: 3633.7" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 71.4;ependymal cell: 254.1" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 16.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Kidney cancer: 7.0;testis cancer: 8.9" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Late spermatids" "Low region specificity" "Detected in many" "Region enhanced" "Detected in all" "midbrain: 22.2" "Cell type enriched" "Detected in some" "Fallopian tube cells: 201305418.1" "Tissue enriched" "Detected in many" "intestine: 84860887.6" "HPA036854, HPA036855" Enhanced Supported Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 17 Mitochondria "Nucleoplasm, Cytosol" "HPA036854: , HPA036855: " "unprognostic (1.23e-1)" "unprognostic (6.78e-2)" "unprognostic (2.93e-1)" "unprognostic (7.60e-2)" "unprognostic (1.29e-3)" "unprognostic (2.95e-2)" "unprognostic (3.21e-3)" "unprognostic (3.12e-2)" "unprognostic (2.01e-2)" "unprognostic (1.19e-3)" "potential prognostic favorable (5.14e-14)" "unprognostic (1.39e-3)" "potential prognostic favorable (7.31e-12)" "unprognostic (1.18e-1)" "potential prognostic favorable (5.39e-6)" "unprognostic (1.67e-2)" "unprognostic (1.66e-1)" "unprognostic (1.52e-1)" "unprognostic (3.58e-1)" "unprognostic (1.36e-1)" "unprognostic (7.57e-2)" "unprognostic (2.07e-1)" "unprognostic (5.12e-2)" "unprognostic (1.35e-1)" "unprognostic (2.71e-2)" "unprognostic (1.14e-1)" "unprognostic (6.03e-2)" "unprognostic (3.54e-1)" "unprognostic (1.28e-1)" "unprognostic (7.32e-3)" "unprognostic (2.21e-2)" SPATA2 "KIAA0757, PD1, PPP1R145, tamo" ENSG00000158480 "Spermatogenesis associated 2" Q9UM82 20 49903391-49915529 "Predicted intracellular proteins" Necrosis "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 38.9;Late primary spermatocytes: 84.3;Late spermatids: 94.7;Syncytiotrophoblasts: 40.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 94.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Spleen - Endothelial cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 5824593.8;Collecting ducts: 3313559.4;Microglia and Neuropil: 9711884.0;Neurons: 2781705.1" "Tissue enriched" "Detected in some" "cerebral cortex: 6957681.6" "HPA048581, HPA052224" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 62: Non-specific - Plasma proteins" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 32 "Nucleoli fibrillar center" Nucleoplasm "HPA048581: , HPA052224: " "unprognostic (1.66e-2)" "unprognostic (3.41e-2)" "unprognostic (3.65e-2)" "unprognostic (1.40e-1)" "unprognostic (3.22e-2)" "unprognostic (8.40e-2)" "unprognostic (1.89e-1)" "unprognostic (6.80e-2)" "unprognostic (1.28e-1)" "unprognostic (8.50e-2)" "unprognostic (1.35e-3)" "unprognostic (1.07e-1)" "unprognostic (3.03e-1)" "potential prognostic unfavorable (8.78e-4)" "unprognostic (2.13e-3)" "unprognostic (3.48e-1)" "unprognostic (3.88e-2)" "unprognostic (1.33e-2)" "unprognostic (4.56e-2)" "unprognostic (4.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.19e-2)" "unprognostic (1.40e-2)" "unprognostic (1.70e-1)" "unprognostic (2.08e-3)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (3.69e-2)" "unprognostic (1.78e-1)" "potential prognostic unfavorable (1.13e-4)" "unprognostic (1.35e-1)" SPATA21 "spergen-2, spergen2" ENSG00000187144 "Spermatogenesis associated 21" Q7Z572 1 16387117-16437424 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 9 "testis: 7.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 57.8;Early spermatids: 109.3;Epicardial cells: 122.8;Late primary spermatocytes: 57.4;Late spermatids: 66.1" "Group enriched" "Detected in many" 4 "Barrier epithelial cells: 122.8;Myocytes: 57.8;Spermatogenic cell types: 109.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.7" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1092 "Fallopian tube cells: 109167.3" "Tissue enriched" "Detected in single" 37 "salivary gland: 3694.0" HPA032080 Approved Vesicles,Cytosol No NA "Cluster 46: Basophils - Proteolysis" "Cluster 57: Testis - Spermatogenesis" "Cluster 48: Non-specific - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 77: Late primary spermatocytes - Spermiogenesis: Golgi Phase" "Vesicles, Cytosol" "HPA032080: " "unprognostic (5.64e-2)" "unprognostic (4.21e-1)" "unprognostic (3.41e-3)" "unprognostic (1.42e-2)" "unprognostic (1.62e-1)" SPATA7 "HSD3, LCA3" ENSG00000042317 "Spermatogenesis associated 7" Q9P0W8 14 88384924-88470350 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Leber congenital amaurosis, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "testis: 53.2" "Cell type enhanced" "Detected in many" "Early spermatids: 1093.6;Late primary spermatocytes: 377.5;Late spermatids: 1636.5" "Cell type enriched" "Detected in many" 8 "Spermatogenic cell types: 1636.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 2447603.4" "Tissue enriched" "Detected in single" 3806 "fallopian tube: 380626.4" "HPA038082, HPA038083" Enhanced Supported "Vesicles,Primary cilium transition zone,Mid piece" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 21: Testis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" "Vesicles, Primary cilium transition zone, Mid piece" "HPA038082: , HPA038083: " "unprognostic (2.27e-1)" "unprognostic (5.36e-2)" "unprognostic (4.88e-2)" "unprognostic (1.13e-1)" "unprognostic (2.25e-1)" "unprognostic (7.55e-2)" "unprognostic (2.65e-2)" "unprognostic (2.59e-1)" "unprognostic (1.78e-2)" "unprognostic (2.73e-1)" "potential prognostic favorable (5.85e-10)" "unprognostic (1.79e-3)" "potential prognostic favorable (2.07e-4)" "unprognostic (1.53e-2)" "potential prognostic favorable (6.21e-5)" "unprognostic (2.01e-2)" "unprognostic (1.38e-1)" "unprognostic (5.19e-2)" "unprognostic (1.47e-1)" "unprognostic (2.93e-2)" "unprognostic (9.45e-3)" "potential prognostic favorable (1.93e-4)" "unprognostic (1.75e-1)" "unprognostic (1.02e-1)" "unprognostic (3.26e-1)" "unprognostic (3.80e-2)" "unprognostic (1.09e-1)" "unprognostic (3.62e-2)" "unprognostic (3.53e-1)" "unprognostic (1.55e-1)" "unprognostic (7.79e-2)" SPATS2 "FLJ13117, SCR59, SPATA10" ENSG00000123352 "Spermatogenesis associated serine rich 2" Q86XZ4 12 49366584-49527425 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 394.3;Plasma cells: 440.6" "Cell type enhanced" "Detected in all" "Plasma cells: 440.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "B-cells: 5.9;dendritic cells: 7.8" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 547768.2;Oocytes: 511972.7" "Tissue enriched" "Detected in many" "intestine: 4562756.1" "HPA038642, HPA038643, HPA076823" Uncertain Enhanced Cytosol NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 27 Cytosol "HPA038642: , HPA038643: , HPA076823: " "unprognostic (2.14e-1)" "unprognostic (7.99e-3)" "unprognostic (2.32e-3)" "unprognostic (6.05e-2)" "unprognostic (1.08e-1)" "unprognostic (1.72e-2)" "unprognostic (1.96e-1)" "unprognostic (2.62e-3)" "unprognostic (6.77e-2)" "unprognostic (1.42e-2)" "unprognostic (1.66e-1)" "unprognostic (2.96e-1)" "unprognostic (9.08e-2)" "potential prognostic unfavorable (2.17e-7)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (7.85e-2)" "unprognostic (1.91e-1)" "unprognostic (5.34e-2)" "unprognostic (1.12e-2)" "unprognostic (1.46e-1)" "unprognostic (1.65e-1)" "unprognostic (1.96e-3)" "unprognostic (1.82e-1)" "unprognostic (7.67e-2)" "unprognostic (7.13e-2)" "potential prognostic unfavorable (8.17e-4)" "unprognostic (1.27e-1)" "unprognostic (6.93e-2)" "unprognostic (8.92e-3)" "unprognostic (1.24e-2)" SPC24 "FLJ90806, SPBC24" ENSG00000161888 "SPC24 component of NDC80 kinetochore complex" Q8NBT2 19 11131520-11155807 "Essential proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 24.3;lymphoid tissue: 13.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 24.2;Epicardial cells: 134.2;Erythrocyte progenitors: 48.6;Hofbauer cells: 28.7;Megakaryocyte progenitors: 31.0;Monocyte progenitors: 39.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 134.2;Erythrocytes: 48.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Granulosa cells: 4122857.6;Neutrophils: 2975971.8;Oocytes: 5946440.5" "Tissue enriched" "Detected in some" "bone marrow: 17156007.3" HPA051234 Approved Supported Nucleoplasm,Nucleoli NA Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 48: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 38 Nucleoplasm Nucleoli "HPA051234: " "unprognostic (2.88e-2)" "unprognostic (2.51e-1)" "unprognostic (4.19e-2)" "unprognostic (3.07e-3)" "unprognostic (8.17e-2)" "unprognostic (2.52e-1)" "unprognostic (1.07e-1)" "unprognostic (9.27e-2)" "unprognostic (1.46e-2)" "potential prognostic unfavorable (3.86e-4)" "validated prognostic unfavorable (4.56e-12)" "validated prognostic unfavorable (9.67e-5)" "potential prognostic unfavorable (3.32e-7)" "validated prognostic unfavorable (6.53e-4)" "validated prognostic unfavorable (2.57e-5)" "validated prognostic unfavorable (2.76e-5)" "validated prognostic unfavorable (2.32e-4)" "unprognostic (2.67e-2)" "unprognostic (2.68e-3)" "unprognostic (8.70e-2)" "unprognostic (6.63e-2)" "unprognostic (1.99e-3)" "unprognostic (1.65e-2)" "unprognostic (4.09e-3)" "unprognostic (2.53e-1)" "unprognostic (2.15e-1)" "unprognostic (1.07e-2)" "unprognostic (6.20e-2)" "unprognostic (1.12e-1)" "unprognostic (7.30e-2)" "unprognostic (2.43e-1)" SPEF2 "CT122, FLJ23577, KPL2" ENSG00000152582 "Sperm flagellar 2" Q9C093 5 35617844-35814611 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 771.7;Endometrial ciliated cells: 303.3;Ependymal cells: 1033.1;Epididymal efferent duct ciliated cells: 268.6;Fallopian tube ciliated cells: 419.1;Respiratory ciliated cells: 713.1" "Cell type enriched" "Detected in many" 6 "Ciliated cells: 1033.1" "Group enriched" "Detected in all" 5 "choroid plexus epithelial cell: 680.5;ependymal cell: 1106.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 46.8" "Group enriched" "Detected in many" 6 "gdT-cell: 3.2;MAIT T-cell: 4.0;memory CD4 T-cell: 1.9;memory CD8 T-cell: 3.4;naive CD4 T-cell: 2.1;naive CD8 T-cell: 2.6;NK-cell: 3.0" "Group enriched" "Detected in many" 8 "NK-cells: 3.0;T-cells: 4.0" "Low cancer specificity" "Detected in many" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 39793 "Fallopian tube cells: 3979301.4" "Group enriched" "Detected in some" 12547 "fallopian tube: 1835466.0;heart muscle: 673973.6" "HPA039606, HPA040343" Enhanced Supported "Nuclear bodies,Primary cilium,Cytosol,Flagellar centriole,Mid piece" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" "Primary cilium, Flagellar centriole" "Nuclear bodies, Cytosol, Mid piece" "HPA039606: , HPA040343: " "unprognostic (2.07e-1)" "unprognostic (1.20e-1)" "unprognostic (1.31e-1)" "unprognostic (1.39e-1)" "unprognostic (1.36e-1)" "unprognostic (2.19e-2)" "unprognostic (1.11e-2)" "unprognostic (3.06e-2)" "unprognostic (2.87e-3)" "unprognostic (7.75e-3)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (2.97e-4)" "unprognostic (1.11e-1)" "unprognostic (2.26e-1)" "unprognostic (3.56e-1)" "unprognostic (3.27e-1)" "unprognostic (1.81e-2)" "unprognostic (2.15e-1)" "unprognostic (3.38e-1)" "potential prognostic favorable (1.74e-5)" "unprognostic (5.25e-2)" "unprognostic (4.66e-2)" "unprognostic (6.42e-3)" "unprognostic (3.98e-2)" "unprognostic (2.71e-2)" "unprognostic (9.08e-2)" "unprognostic (5.34e-3)" "unprognostic (4.17e-1)" SPEM1 "C17orf83, FLJ40081" ENSG00000181323 "Spermatid maturation 1" Q8N4L4 17 7420324-7421632 "Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 368 "testis: 70.6" "Cell type enriched" "Detected in some" 8 "Late spermatids: 3332.3" "Cell type enriched" "Detected in some" 745 "Spermatogenic cell types: 3332.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017723, HPA077535" Approved "Golgi apparatus,Calyx" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 1 "Golgi apparatus" Calyx "HPA017723: , HPA077535: " SPESP1 SP-ESP ENSG00000258484 "Sperm equatorial segment protein 1" Q6UW49 15 68818221-68946811 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 68.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 43.7;Ependymal cells: 39.1;Late primary spermatocytes: 42.1;Renal collecting duct intercalated cells: 40.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 12.9;skin cancer: 11.0" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045936, HPA051040" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Acrosome,Equatorial segment" "Secreted in male reproductive system" "Developmental protein" Yes NA 37000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 57: Testis - Spermatogenesis" "Cluster 30: White matter - Myelination" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" "Acrosome, Equatorial segment" "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA045936: , HPA051040: " "unprognostic (3.14e-1)" "unprognostic (9.60e-2)" "unprognostic (2.37e-1)" "unprognostic (9.49e-2)" "unprognostic (1.61e-1)" "unprognostic (1.14e-2)" "unprognostic (2.35e-2)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.38e-3)" "unprognostic (1.25e-2)" "unprognostic (1.84e-2)" "unprognostic (2.21e-1)" "unprognostic (1.00e-1)" "unprognostic (2.39e-1)" "unprognostic (2.01e-2)" "unprognostic (4.88e-2)" "unprognostic (3.39e-1)" "unprognostic (1.11e-1)" "unprognostic (8.21e-2)" "unprognostic (4.65e-2)" "unprognostic (8.91e-3)" "unprognostic (2.67e-2)" "unprognostic (3.13e-1)" "unprognostic (1.54e-3)" "unprognostic (1.11e-1)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (2.98e-4)" SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 51.7;Breast secretory cells: 104.4;Cholangiocytes: 60.9;Decidual stromal cells: 86.4;Endometrial glandular cells: 77.3;Epididymal basal cells: 61.7;Esophageal apical cells: 194.5;Lymphatic endothelial cells: 63.8;Müller glia: 141.8;Ocular epithelial cells: 54.5;Pancreatic duct cells: 77.8;Platelets: 132.4;Schwann cells: 53.6" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 194.5;Glial cells: 141.8;Platelets: 132.4" "Cell type enhanced" "Detected in many" "lower rhombic lip: 9.2;vascular associated smooth muscle cell: 8.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Endothelial cells, Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "olfactory bulb: 7.6" "Group enriched" "Detected in some" 530 "Alveolar cell types: 57606.3;Capillaries: 38659.7;Distal tubules: 53250.6;Macrophages: 62600.8" "Group enriched" "Detected in some" 498 "lung: 45293.5;lymphoid tissue: 54355.2" "HPA022829, HPA028761" Uncertain Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium transition zone" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 6 "Plasma membrane" "Vesicles, Primary cilium, Primary cilium transition zone" "HPA022829: , HPA028761: " "unprognostic (8.79e-2)" "unprognostic (3.30e-2)" "unprognostic (2.90e-1)" "unprognostic (1.43e-1)" "unprognostic (7.15e-3)" "unprognostic (4.47e-2)" "potential prognostic unfavorable (9.54e-4)" "unprognostic (2.81e-1)" "unprognostic (1.79e-1)" "unprognostic (1.35e-2)" "potential prognostic unfavorable (1.77e-5)" "unprognostic (3.26e-1)" "unprognostic (5.94e-2)" "unprognostic (9.57e-3)" "unprognostic (1.51e-2)" "potential prognostic unfavorable (6.51e-5)" "unprognostic (6.52e-3)" "unprognostic (1.02e-1)" "unprognostic (1.79e-1)" "unprognostic (2.22e-2)" "unprognostic (2.28e-1)" "unprognostic (8.84e-3)" "unprognostic (3.05e-2)" "unprognostic (2.40e-2)" "unprognostic (5.75e-2)" "unprognostic (1.88e-2)" "unprognostic (3.06e-1)" "unprognostic (1.48e-1)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" "unprognostic (2.39e-2)" SPI1 "OF, PU.1, SFPI1, SPI-1, SPI-A" ENSG00000066336 "Spi-1 proto-oncogene" P17947 11 47354860-47378547 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding, RNA-binding" "Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 316.4;lung: 98.6;lymphoid tissue: 167.9" "Cell type enhanced" "Detected in many" "cDC: 416.6;Hofbauer cells: 502.2;Kupffer cells: 449.9;Macrophages: 295.4;Monocyte progenitors: 229.0;monocytes: 448.8;Neutrophil progenitors: 394.2;Neutrophils: 1363.9" "Group enriched" "Detected in many" 8 "dendritic cells: 416.6;Mononuclear phagocytes: 502.2;Neutrophils: 1363.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 118.3;leukocyte: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 180.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 180.0" "Group enriched" "Detected in some" 15 "Leukemia: 134.6;lymphoma: 69.7" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Lung - Neutrophils_2, Minor Salivary Gland - Macrophages, Pituitary gland - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Spleen - Neutrophils_2, Stomach - Macrophages, Testis - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neutrophils: 25835384.4" "Tissue enriched" "Detected in some" "bone marrow: 1513640.5" "CAB004079, HPA044653" Enhanced Supported Nucleoplasm NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 25 Nucleoplasm "CAB004079: , HPA044653: " "unprognostic (3.27e-2)" "unprognostic (8.89e-3)" "unprognostic (3.79e-2)" "unprognostic (3.28e-2)" "unprognostic (4.35e-2)" "unprognostic (3.73e-1)" "unprognostic (1.08e-2)" "unprognostic (1.22e-1)" "unprognostic (2.90e-2)" "unprognostic (3.30e-1)" "unprognostic (2.50e-2)" "unprognostic (2.74e-1)" "unprognostic (6.94e-2)" "unprognostic (2.90e-2)" "unprognostic (1.54e-1)" "unprognostic (1.79e-2)" "unprognostic (1.69e-1)" "unprognostic (1.39e-1)" "unprognostic (2.57e-1)" "unprognostic (2.15e-1)" "unprognostic (6.71e-2)" "unprognostic (1.22e-1)" "unprognostic (3.11e-3)" "unprognostic (2.49e-1)" "unprognostic (8.10e-2)" "unprognostic (1.18e-1)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (7.46e-3)" "unprognostic (2.17e-1)" "unprognostic (1.69e-1)" SPICE1 "CCDC52, SPICE" ENSG00000163611 "Spindle and centriole associated protein 1" Q8N0Z3 3 113442718-113515187 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 33.4;Bergmann glia: 43.5;Brain excitatory neurons: 28.8;Choroid plexus epithelial cells: 71.9;Distal convoluted tubule cells: 47.3;Ependymal cells: 83.5;Loop of henle epithelial cells: 41.9;Oligodendrocyte progenitor cells: 28.5;Papillary tip epithelial cells: 41.0;Podocytes: 42.6;Proximal tubule cells: 45.5;Renal collecting duct intercalated cells: 40.3;Renal collecting duct principal cells: 44.5;Renal connecting tubule cells: 51.7" "Group enriched" "Detected in many" 4 "Ciliated cells: 83.5;Ductal cells: 51.7;Glial cells: 43.5;Neuronal cells: 28.8;Renal nephron cells: 47.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 3292450.5" "Tissue enriched" "Detected in some" "lymphoid tissue: 120641.8" HPA064843 Approved Supported "Centrosome,Basal body" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 34: Ciliated cells - Cilia assembly & function" 26 "Centrosome, Basal body" "HPA064843: " "unprognostic (7.54e-3)" "unprognostic (1.49e-1)" "unprognostic (5.94e-2)" "unprognostic (2.42e-1)" "unprognostic (1.11e-1)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "unprognostic (1.94e-1)" "unprognostic (5.34e-3)" "potential prognostic favorable (1.52e-4)" "unprognostic (3.91e-2)" "unprognostic (3.88e-1)" "unprognostic (4.63e-2)" "unprognostic (1.64e-1)" "unprognostic (3.88e-2)" "unprognostic (3.16e-3)" "unprognostic (7.14e-2)" "unprognostic (2.61e-1)" "unprognostic (1.36e-1)" "unprognostic (5.42e-2)" "potential prognostic unfavorable (3.38e-4)" "unprognostic (1.79e-2)" "unprognostic (4.22e-2)" "unprognostic (3.73e-2)" "unprognostic (3.59e-2)" "unprognostic (8.65e-3)" "unprognostic (2.26e-2)" "unprognostic (2.69e-1)" "unprognostic (1.05e-2)" "unprognostic (3.13e-1)" SPINK2 HUSI-II ENSG00000128040 "Serine peptidase inhibitor Kazal type 2" P20155 4 56809860-56821742 "Disease related genes, Human disease related genes, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 15 "epididymis: 4955.9" "Cell type enriched" "Detected in many" 6 "Epididymal principal cells: 27209.1" "Cell type enriched" "Detected in many" 6 "Reproductive supporting cells: 27209.1" "Cell type enhanced" "Detected in some" "endothelial cell: 5.0;leukocyte: 4.1" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 6.4" "Region enriched" "Detected in single" 5 "choroid plexus: 3.7" "Immune cell enriched" "Detected in many" 7 "NK-cell: 143.9" "Lineage enriched" "Detected in many" 7 "NK-cells: 143.9" "Group enriched" "Detected in some" 12 "Leukemia: 23.4;lymphoma: 17.3;Myeloma: 13.7" "Pituitary gland - Gonadotropes, Stomach - Plasma cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020824, HPA026813" Enhanced Supported "Acrosome,Equatorial segment" "Secreted to blood" "Enzyme inhibitor" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 30: Epididymal principal cells - Sperm storage microenvironment" 6 Acrosome "Equatorial segment" "CAB020824: , HPA026813: " "unprognostic (2.47e-1)" "unprognostic (3.17e-2)" "potential prognostic favorable (2.66e-4)" "unprognostic (1.85e-1)" "unprognostic (9.57e-3)" "unprognostic (4.99e-3)" "unprognostic (2.22e-1)" "unprognostic (2.85e-2)" "unprognostic (2.29e-1)" SPINK5 "DKFZp686K19184, FLJ21544, FLJ97536, FLJ97596, FLJ99794, LEKTI, LETKI, NETS, NS, VAKTI" ENSG00000133710 "Serine peptidase inhibitor Kazal type 5" Q9NQ38 5 148025683-148137382 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 538.7;esophagus: 953.6;lymphoid tissue: 274.6;skin 1: 300.2;vagina: 552.2" "Cell type enriched" "Detected in many" 7 "Esophageal apical cells: 47706.3" "Cell type enriched" "Detected in many" 7 "Apical squamous epithelial cells: 47706.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 46.2;Head and Neck Squamous Cell Carcinoma (TCGA): 71.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 21.4" "Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary gland basal cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Keratinocytes: 4691019.1" "Low tissue specificity" "Detected in all" "HPA009067, HPA011351, CAB015347" Enhanced Enhanced Vesicles "Secreted in other tissues" "Enzyme inhibitor" NA NA 43000000 "Cluster 81: Squamous epithelium - Keratinization" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Vesicles "CAB015347: , HPA009067: , HPA011351: " "unprognostic (1.18e-1)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (1.11e-1)" "unprognostic (2.27e-1)" "unprognostic (1.45e-3)" "unprognostic (1.26e-1)" "potential prognostic favorable (3.90e-5)" "unprognostic (1.78e-1)" "unprognostic (6.02e-2)" "unprognostic (3.98e-1)" "unprognostic (1.11e-2)" "unprognostic (1.96e-2)" "potential prognostic favorable (7.12e-4)" "unprognostic (2.61e-1)" "unprognostic (2.27e-1)" "unprognostic (2.32e-3)" "unprognostic (9.23e-2)" "unprognostic (4.34e-1)" "unprognostic (3.06e-1)" "unprognostic (3.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.56e-1)" "unprognostic (3.03e-1)" "unprognostic (1.67e-1)" "unprognostic (1.75e-2)" SPINK9 ENSG00000204909 "Serine peptidase inhibitor Kazal type 9" Q5DT21 5 148321203-148339852 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.3;lymphoid tissue: 2.6;retina: 2.0" "Cell type enriched" "Detected in some" 4 "Cardiomyocytes: 90.5" "Cell type enriched" "Detected in many" 4 "Myocytes: 90.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 6.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" HPA038288 Uncertain Approved Nucleoplasm,Vesicles "Secreted in other tissues" "Enzyme inhibitor" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nucleoplasm, Vesicles" "HPA038288: " "unprognostic (1.01e-1)" "unprognostic (4.47e-2)" "unprognostic (5.64e-2)" "unprognostic (2.03e-3)" "unprognostic (1.48e-1)" "unprognostic (2.77e-2)" "unprognostic (9.30e-2)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.82e-2)" "unprognostic (1.67e-1)" "unprognostic (2.65e-1)" "unprognostic (3.07e-3)" "unprognostic (2.13e-1)" "unprognostic (1.26e-1)" "unprognostic (1.51e-1)" "unprognostic (1.91e-1)" "unprognostic (3.08e-1)" "unprognostic (6.36e-2)" "unprognostic (5.49e-3)" "unprognostic (5.77e-2)" "unprognostic (2.14e-3)" "unprognostic (3.67e-2)" "unprognostic (1.53e-1)" "unprognostic (2.19e-1)" "unprognostic (1.13e-1)" "unprognostic (2.21e-2)" "unprognostic (1.17e-1)" SPN "CD43, GPL115, LEU-22, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 67.7;lung: 26.6;lymphoid tissue: 47.6" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 5.8;Erythrocytes: 1.5;Hematopoietic stem cells: 2.4;Mast cells: 1.3;Megakaryocyte progenitors: 9.8;Megakaryocyte-Erythroid progenitors: 7.3;Monocyte progenitors: 2.1;Neutrophil progenitors: 2.7;NK-cells: 2.7;T-cells: 1.3;Thymocytes: 4.2" "Cell type enhanced" "Detected in some" "Erythrocytes: 5.8;Megakaryocytes: 9.8;Neutrophils: 2.7;NK-cells: 2.7;T-cells: 4.2" "Cell type enhanced" "Detected in single" "leukocyte: 1.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.5" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Leukemia: 185.3;Myeloma: 49.9" "Prostate - T-cells, Skin - Langerhans cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cell types: 7995241.7;T-cells: 14631571.0" "Tissue enriched" "Detected in many" "bone marrow: 47168692.9" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 6100 "Cluster 33: Non-specific - ATP binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 31 "Plasma membrane" "CAB002666: , HPA055244: " "unprognostic (1.56e-2)" "unprognostic (1.28e-2)" "unprognostic (2.02e-2)" "unprognostic (2.08e-1)" "unprognostic (3.64e-1)" "unprognostic (5.85e-2)" "unprognostic (1.35e-1)" "unprognostic (2.40e-1)" "unprognostic (1.50e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (9.85e-4)" "unprognostic (5.44e-2)" "unprognostic (1.08e-1)" "unprognostic (4.84e-2)" "unprognostic (2.42e-2)" "unprognostic (3.57e-3)" "unprognostic (3.70e-2)" "unprognostic (6.73e-2)" "unprognostic (2.16e-1)" "unprognostic (3.05e-1)" "unprognostic (2.78e-1)" "unprognostic (7.40e-2)" "unprognostic (2.55e-1)" "unprognostic (1.31e-1)" "unprognostic (8.46e-2)" "unprognostic (3.08e-1)" "unprognostic (1.34e-3)" "unprognostic (1.97e-2)" "unprognostic (2.70e-2)" "unprognostic (8.47e-2)" "unprognostic (4.74e-2)" SPON2 DIL1 ENSG00000159674 "Spondin 2" Q9BUD6 4 1166932-1208962 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 186.3" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 928.1;Endometrial stromal cells: 208.7;Extravillous trophoblasts: 565.6;Fibroblasts: 190.2;Hepatic stellate cells: 206.6;NK-cells: 357.1;Thymocytes: 213.4" "Cell type enhanced" "Detected in many" "NK-cells: 357.1;Stromal cells: 928.1;Trophoblast cells: 565.6" "Cell type enhanced" "Detected in all" "leukocyte: 161.0" "Cancer enriched" "Detected in all" 5 "Prostate Adenocarcinoma (TCGA): 1231.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 256.9" "Lineage enriched" "Detected in all" 5 "T-cells: 256.9" "Cancer enriched" "Detected in many" 9 "prostate cancer: 639.9" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Pituitary gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" "intestine: 205263.0;Stomach: 509050.9" "HPA040170, HPA066095" Approved Approved Vesicles "Secreted to blood" Immunity NA NA 1600000 "Cluster 1: T-cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 108: Fibroblasts - ECM organization" 3 Vesicles "HPA040170: , HPA066095: " "unprognostic (5.69e-2)" "unprognostic (9.16e-2)" "unprognostic (7.16e-3)" "unprognostic (1.68e-1)" "unprognostic (1.04e-2)" "unprognostic (9.90e-2)" "unprognostic (4.38e-2)" "unprognostic (8.95e-3)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "potential prognostic unfavorable (9.91e-6)" "unprognostic (2.25e-1)" "potential prognostic favorable (4.93e-4)" "unprognostic (2.89e-3)" "unprognostic (1.74e-2)" "unprognostic (2.34e-3)" "unprognostic (3.83e-3)" "unprognostic (1.27e-2)" "unprognostic (8.49e-3)" "unprognostic (1.07e-1)" "unprognostic (5.77e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" "unprognostic (7.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.30e-3)" "unprognostic (3.33e-1)" "unprognostic (7.44e-3)" "unprognostic (2.32e-1)" "unprognostic (3.11e-2)" "unprognostic (4.14e-1)" SPRR4 ENSG00000184148 "Small proline rich protein 4" Q96PI1 1 152970648-152972574 "Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "skin 1: 135.5" "Cell type enriched" "Detected in some" 8 "Late spermatids: 119.6" "Cell type enriched" "Detected in some" 20 "Spermatogenic cell types: 119.6" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 28.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "Esophageal cancer: 2.0;head and neck cancer: 1.7" "Skin - Sebaceous gland cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA055963 Enhanced Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 37: Skin - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nucleoplasm, Cytosol" "Nuclear membrane" "HPA055963: " "unprognostic (2.25e-1)" "unprognostic (1.21e-2)" "unprognostic (1.11e-2)" "unprognostic (7.77e-3)" "unprognostic (1.97e-1)" "unprognostic (7.01e-2)" SPRY4 ENSG00000187678 "Sprouty RTK signaling antagonist 4" Q9C004 5 142310427-142326455 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 37.8;Adrenal medulla cells: 74.5;Alveolar cells type 2: 98.0;Bergmann glia: 35.4;Oligodendrocyte progenitor cells: 99.5;Pericytes: 42.1;Pituicytes/FSCs: 65.4;Vascular endothelial cells: 36.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 74.5;Alveolar cells: 98.0;Glial cells: 99.5" "Cell type enhanced" "Detected in many" "fibroblast: 101.7;oligodendrocyte precursor cell: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 70.1" "Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 184 "Alveolar cell types: 18370.0" "Tissue enriched" "Detected in single" 95 "cerebral cortex: 9472.4" "CAB008086, HPA055471, HPA072661" Enhanced Approved "Golgi apparatus,Cytosol" NA NA "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 23: Choroid plexus - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 47 "Golgi apparatus" Cytosol "CAB008086: , HPA055471: , HPA072661: " "unprognostic (1.71e-2)" "unprognostic (6.90e-3)" "unprognostic (8.84e-2)" "unprognostic (3.46e-3)" "unprognostic (2.27e-1)" "unprognostic (2.82e-3)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (5.80e-4)" "unprognostic (4.62e-2)" "unprognostic (2.43e-1)" "validated prognostic favorable (2.13e-5)" "validated prognostic favorable (1.31e-4)" "unprognostic (6.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.61e-3)" "unprognostic (2.14e-1)" "unprognostic (1.30e-2)" "unprognostic (4.12e-2)" "unprognostic (3.91e-1)" "unprognostic (6.89e-3)" "unprognostic (1.28e-1)" "unprognostic (1.10e-1)" "unprognostic (4.77e-2)" "unprognostic (6.85e-2)" "unprognostic (3.45e-1)" "unprognostic (1.07e-1)" "unprognostic (1.12e-1)" "unprognostic (2.73e-2)" "unprognostic (7.80e-2)" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Fallopian tube cells: 2584282.2;Oocytes: 1477903.1" "Group enriched" "Detected in many" "bone marrow: 2058143.2;intestine: 2425492.3" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 24: Neurons - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 62: Smooth muscle cells - Muscle contraction" 12 "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: , HPA039685: " "unprognostic (9.26e-2)" "unprognostic (1.72e-2)" "unprognostic (2.81e-2)" "unprognostic (1.63e-2)" "unprognostic (1.64e-1)" "unprognostic (1.54e-2)" "unprognostic (8.53e-2)" "unprognostic (3.03e-1)" "unprognostic (7.88e-3)" "unprognostic (1.85e-1)" "potential prognostic favorable (7.71e-9)" "unprognostic (1.72e-3)" "potential prognostic favorable (5.40e-4)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (1.02e-3)" "unprognostic (1.66e-1)" "unprognostic (1.21e-1)" "unprognostic (1.11e-1)" "unprognostic (4.45e-2)" "unprognostic (4.53e-2)" "unprognostic (1.36e-2)" "unprognostic (1.11e-2)" "unprognostic (3.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.19e-2)" "unprognostic (1.10e-1)" "unprognostic (1.47e-1)" "unprognostic (1.93e-1)" "unprognostic (7.08e-2)" "unprognostic (9.69e-2)" "unprognostic (2.23e-1)" SPTLC1 "hLCB1, HSAN1, HSN1, LCB1, SPTI" ENSG00000090054 "Serine palmitoyltransferase long chain base subunit 1" O15269 9 92000087-92115413 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Acyltransferase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 738.2" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 738.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA010860, CAB018747, HPA063907" Supported Supported "Endoplasmic reticulum" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 84: Apical squamous epithelium - Cornification" 38 "Endoplasmic reticulum" "CAB018747: , HPA010860: , HPA063907: " "unprognostic (1.78e-1)" "unprognostic (8.01e-2)" "unprognostic (1.46e-2)" "unprognostic (1.31e-2)" "unprognostic (1.72e-1)" "unprognostic (3.11e-1)" "unprognostic (7.35e-2)" "unprognostic (5.59e-2)" "unprognostic (2.74e-3)" "unprognostic (4.16e-1)" "potential prognostic favorable (9.74e-7)" "unprognostic (8.06e-3)" "unprognostic (4.70e-3)" "unprognostic (9.01e-3)" "unprognostic (5.06e-2)" "unprognostic (2.11e-3)" "unprognostic (5.37e-2)" "unprognostic (7.09e-2)" "unprognostic (3.16e-1)" "unprognostic (9.35e-2)" "unprognostic (6.61e-3)" "unprognostic (2.29e-3)" "unprognostic (7.63e-2)" "unprognostic (5.46e-2)" "unprognostic (1.14e-2)" "unprognostic (2.36e-1)" "unprognostic (1.15e-1)" "unprognostic (5.99e-2)" "unprognostic (5.21e-2)" "unprognostic (3.37e-1)" "unprognostic (2.29e-1)" SQSTM1 "A170, OSIL, p60, p62, p62B, PDB3" ENSG00000161011 "Sequestosome 1" Q13501 5 179806398-179838078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Autophagy, Differentiation, Immunity" "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 992.1" "Cell type enhanced" "Detected in all" "Colonocytes: 455.7;Goblet cells: 340.9;Ocular epithelial cells: 289.4" "Cell type enhanced" "Detected in all" "Enterocytes: 455.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004587, HPA064165, HPA068843" Supported Supported Vesicles,Cytosol No No 81000 "Cluster 21: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 7: Liver cancer - Metabolism" "Cluster 65: Non-specific - Cell growth & division" 386 "Vesicles, Cytosol" "CAB004587: , HPA064165: , HPA068843: " "unprognostic (6.20e-2)" "unprognostic (2.11e-2)" "unprognostic (8.40e-2)" "unprognostic (2.59e-1)" "unprognostic (1.27e-1)" "unprognostic (3.07e-2)" "unprognostic (2.44e-2)" "unprognostic (8.04e-3)" "unprognostic (6.67e-2)" "unprognostic (4.49e-2)" "potential prognostic favorable (8.99e-4)" "unprognostic (1.63e-1)" "unprognostic (2.66e-3)" "potential prognostic unfavorable (5.76e-6)" "unprognostic (1.56e-1)" "unprognostic (6.20e-2)" "unprognostic (1.59e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (4.41e-3)" "unprognostic (2.99e-3)" "unprognostic (1.57e-1)" "unprognostic (4.14e-1)" "unprognostic (4.89e-1)" "unprognostic (1.82e-2)" "unprognostic (2.92e-2)" "unprognostic (1.54e-1)" "unprognostic (7.49e-2)" "unprognostic (3.79e-2)" "unprognostic (1.45e-1)" "unprognostic (2.74e-1)" SRA1 "SRA, STRAA1" ENSG00000213523 "Steroid receptor RNA activator 1" Q9HD15 5 140537340-140557677 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Activator, Receptor, Ribonucleoprotein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 277.2;Syncytiotrophoblasts: 240.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "heart muscle: 7297830.8" "HPA044598, HPA050153" Approved Supported "Nucleoplasm,Microtubules,Cytokinetic bridge,Primary cilium,Cytosol" Yes NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - DNA binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 3 Nucleoplasm "Microtubules, Cytokinetic bridge, Primary cilium, Cytosol" "HPA044598: , HPA050153: " "unprognostic (9.11e-2)" "unprognostic (4.57e-2)" "potential prognostic unfavorable (8.48e-4)" "unprognostic (6.14e-3)" "unprognostic (1.61e-1)" "unprognostic (1.73e-1)" "unprognostic (4.06e-2)" "unprognostic (1.24e-1)" "unprognostic (8.54e-2)" "unprognostic (4.32e-2)" "potential prognostic unfavorable (9.86e-5)" "unprognostic (3.34e-2)" "unprognostic (5.12e-3)" "unprognostic (4.44e-2)" "unprognostic (9.70e-3)" "unprognostic (9.16e-3)" "unprognostic (3.12e-1)" "unprognostic (2.35e-1)" "unprognostic (2.18e-2)" "unprognostic (9.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.88e-3)" "unprognostic (1.02e-1)" "unprognostic (2.39e-3)" "unprognostic (2.71e-1)" "unprognostic (3.73e-1)" "unprognostic (1.17e-1)" "unprognostic (1.96e-1)" "unprognostic (2.33e-1)" "unprognostic (1.22e-1)" "unprognostic (1.14e-1)" SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 82.5;Foveolar cells: 96.8;Megakaryocytes: 173.1;Platelets: 119.8;Urothelial cells: 121.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 121.7;Megakaryocytes: 173.1;Platelets: 119.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.9" "Group enriched" "Detected in many" 4 "dendritic cells: 1.0;monocytes: 1.9" "Low cancer specificity" "Detected in all" "Spleen - Macrophages, Stomach - Gastric mucous cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB004023, HPA030875" Approved Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 1700000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 17: Intestine - Digestion" "Cluster 29: Forebrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 220 "Vesicles, Plasma membrane, Cell Junctions" "CAB004023: , HPA030875: " "unprognostic (1.20e-1)" "unprognostic (3.66e-2)" "unprognostic (6.36e-2)" "unprognostic (1.40e-3)" "unprognostic (2.16e-1)" "unprognostic (2.57e-1)" "unprognostic (4.56e-1)" "unprognostic (1.45e-2)" "unprognostic (2.42e-1)" "unprognostic (3.26e-1)" "unprognostic (1.08e-2)" "unprognostic (6.32e-3)" "unprognostic (1.48e-1)" "validated prognostic unfavorable (2.14e-4)" "validated prognostic unfavorable (3.05e-5)" "unprognostic (3.55e-2)" "unprognostic (1.19e-2)" "unprognostic (3.20e-2)" "unprognostic (6.00e-2)" "unprognostic (8.52e-3)" "unprognostic (3.78e-1)" "unprognostic (1.82e-2)" "unprognostic (1.52e-2)" "unprognostic (2.98e-2)" "unprognostic (1.28e-2)" "unprognostic (2.58e-1)" "unprognostic (3.70e-2)" "unprognostic (2.12e-2)" "unprognostic (7.89e-2)" "unprognostic (1.48e-1)" "unprognostic (5.15e-3)" SRD5A3 "FLJ13352, SRD5A2L, SRD5A2L1" ENSG00000128039 "Steroid 5 alpha-reductase 3" Q9H8P0 4 55346213-55373100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid metabolism" Oxidoreductase "Cataract, Congenital disorder of glycosylation, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 5.7;Bergmann glia: 5.2;Brain excitatory neurons: 17.9;Brain inhibitory neurons: 22.5;Loop of henle epithelial cells: 5.7;Microglia: 9.2;Oligodendrocyte progenitor cells: 12.8;Oligodendrocytes: 37.8;Other brain neurons: 15.8;Papillary tip epithelial cells: 14.4;Podocytes: 9.5;Renal collecting duct principal cells: 5.5" "Group enriched" "Detected in some" 4 "Glial cells: 37.8;Neuronal cells: 22.5;Renal nephron cells: 14.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA027006 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" "Plasma membrane, Cytosol" "HPA027006: " "unprognostic (1.44e-1)" "unprognostic (1.79e-3)" "unprognostic (2.85e-2)" "unprognostic (2.94e-1)" "unprognostic (3.71e-3)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (1.44e-5)" "unprognostic (2.30e-2)" "unprognostic (2.52e-2)" "unprognostic (7.51e-2)" "potential prognostic unfavorable (9.45e-9)" "unprognostic (8.29e-3)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (7.94e-6)" "unprognostic (3.67e-3)" "unprognostic (2.99e-3)" "potential prognostic unfavorable (8.68e-4)" "unprognostic (3.35e-2)" "unprognostic (2.37e-1)" "unprognostic (7.15e-2)" "unprognostic (1.03e-1)" "unprognostic (5.88e-3)" "unprognostic (1.00e-1)" "unprognostic (7.41e-2)" "unprognostic (1.60e-1)" "unprognostic (2.41e-1)" "unprognostic (1.12e-1)" "unprognostic (1.68e-1)" "unprognostic (1.37e-1)" "unprognostic (2.98e-2)" "unprognostic (3.06e-1)" SRGAP1 "ARHGAP13, KIAA1304" ENSG00000196935 "SLIT-ROBO Rho GTPase activating protein 1" Q7Z6B7 12 63843761-64162217 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bergmann glia: 633.1;Podocytes: 1387.8" "Cell type enhanced" "Detected in many" "Renal nephron cells: 1387.8" "Cell type enhanced" "Detected in all" "Bergmann glia: 654.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 6399550.1;Large ducts: 3483785.8" "Tissue enriched" "Detected in some" "cerebral cortex: 44788.3" "HPA052416, HPA078079" Uncertain Approved "Centrosome,Basal body,Cytosol" NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 13 Cytosol "Centrosome, Basal body" "HPA052416: , HPA078079: " "unprognostic (1.64e-1)" "potential prognostic unfavorable (9.56e-4)" "unprognostic (4.29e-2)" "unprognostic (7.22e-2)" "unprognostic (2.93e-1)" "unprognostic (5.13e-2)" "unprognostic (2.36e-1)" "unprognostic (7.83e-2)" "unprognostic (9.12e-2)" "unprognostic (1.03e-1)" "unprognostic (3.20e-1)" "unprognostic (2.16e-2)" "potential prognostic unfavorable (2.81e-6)" "unprognostic (1.83e-1)" "potential prognostic unfavorable (3.96e-6)" "unprognostic (2.02e-2)" "unprognostic (4.10e-2)" "unprognostic (1.66e-1)" "potential prognostic unfavorable (3.98e-5)" "unprognostic (5.51e-2)" "unprognostic (4.68e-3)" "potential prognostic unfavorable (9.01e-4)" "unprognostic (1.75e-1)" "unprognostic (1.28e-1)" "unprognostic (4.39e-2)" "unprognostic (1.65e-2)" "unprognostic (2.97e-2)" "unprognostic (2.98e-1)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (9.13e-5)" SRGAP2 "ARHGAP34, FNBP2, KIAA0456, SRGAP2A" ENSG00000266028 "SLIT-ROBO Rho GTPase activating protein 2" O75044 1 206203346-206464436 "Disease related genes, Predicted intracellular proteins" Neurogenesis "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 122.7" "Group enriched" "Detected in many" 5 "Microglia: 2480.3;Podocytes: 1255.4" "Group enriched" "Detected in all" 5 "Glial cells: 2480.3;Renal nephron cells: 1255.4" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 2914.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 36603577.0;Microglia and Neuropil: 30034441.1" "Tissue enhanced" "Detected in many" "cerebral cortex: 30527704.2" "HPA028191, HPA028196, HPA078079" Approved Uncertain "Centrosome,Basal body,Cytosol" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 19 Cytosol "Centrosome, Basal body" "HPA028191: , HPA028196: , HPA078079: " "unprognostic (4.17e-2)" "unprognostic (2.36e-2)" "unprognostic (6.23e-2)" "potential prognostic unfavorable (9.29e-4)" "unprognostic (4.32e-2)" "unprognostic (2.84e-3)" "unprognostic (4.75e-2)" "unprognostic (2.73e-1)" "unprognostic (5.81e-3)" "unprognostic (2.11e-3)" "unprognostic (5.52e-2)" "potential prognostic unfavorable (2.26e-4)" "potential prognostic unfavorable (2.21e-4)" "unprognostic (1.44e-2)" "unprognostic (2.09e-1)" "unprognostic (2.74e-3)" "unprognostic (8.29e-2)" "unprognostic (2.84e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-2)" "unprognostic (6.87e-2)" "unprognostic (1.66e-3)" "unprognostic (4.26e-3)" "unprognostic (3.71e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (3.05e-1)" "unprognostic (3.33e-2)" SRGAP2B SRGAP2P2 ENSG00000196369 "SLIT-ROBO Rho GTPase activating protein 2B" P0DMP2 1 144887265-145095528 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 55.9;skin 1: 15.1" "Group enriched" "Detected in many" 4 "Microglia: 457.6;Podocytes: 733.0" "Group enriched" "Detected in many" 4 "Glial cells: 457.6;Renal nephron cells: 733.0" "Cell type enriched" "Detected in all" 4 "central nervous system macrophage: 513.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA078079 Approved "Centrosome,Basal body,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 71: Cerebellum - Nervous system development" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" "Centrosome, Basal body, Cytosol" "HPA078079: " "unprognostic (1.37e-1)" "unprognostic (2.85e-3)" "unprognostic (9.65e-3)" "unprognostic (4.21e-3)" "unprognostic (1.25e-2)" "unprognostic (1.58e-1)" "unprognostic (3.43e-1)" "unprognostic (1.21e-1)" "unprognostic (3.93e-2)" "potential prognostic favorable (4.77e-5)" "unprognostic (1.68e-3)" "potential prognostic unfavorable (1.32e-5)" "unprognostic (1.18e-2)" "unprognostic (7.00e-2)" "unprognostic (1.60e-2)" "unprognostic (7.04e-2)" "unprognostic (3.07e-1)" "unprognostic (1.47e-2)" "unprognostic (1.65e-3)" "unprognostic (6.34e-2)" "potential prognostic unfavorable (4.98e-4)" "unprognostic (8.20e-2)" "unprognostic (2.04e-1)" "unprognostic (9.39e-3)" "unprognostic (2.92e-1)" "unprognostic (3.13e-2)" "unprognostic (1.89e-1)" "unprognostic (3.51e-2)" "unprognostic (4.46e-3)" SRGAP2C SRGAP2P1 ENSG00000171943 "SLIT-ROBO Rho GTPase activating protein 2C" P0DJJ0 1 121184811-121392874 "Predicted intracellular proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 33.8" "Cell type enriched" "Detected in many" 7 "Podocytes: 745.9" "Cell type enriched" "Detected in many" 7 "Renal nephron cells: 745.9" "Cell type enriched" "Detected in single" 4 "central nervous system macrophage: 2.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Spleen - Endothelial cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA078079 Approved "Centrosome,Basal body,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 2: Non-specific - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 57: Podocytes - Glomerular filtration" 9 Cytosol "Centrosome, Basal body" "HPA078079: " "unprognostic (6.33e-3)" "unprognostic (2.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.38e-2)" "unprognostic (1.45e-1)" "unprognostic (1.45e-2)" "unprognostic (2.78e-1)" "unprognostic (3.44e-2)" "unprognostic (7.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.67e-2)" "unprognostic (4.17e-3)" "potential prognostic unfavorable (4.81e-4)" "unprognostic (1.40e-1)" "unprognostic (7.13e-2)" "unprognostic (2.01e-1)" "unprognostic (2.73e-1)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (2.79e-2)" "unprognostic (5.25e-2)" "unprognostic (1.29e-1)" "unprognostic (7.08e-2)" "unprognostic (1.12e-2)" "unprognostic (2.25e-1)" "unprognostic (6.77e-2)" "unprognostic (1.32e-1)" "unprognostic (2.00e-1)" "unprognostic (8.26e-2)" SRGAP3 "ARHGAP14, KIAA0411, MEGAP, SRGAP2, WRP" ENSG00000196220 "SLIT-ROBO Rho GTPase activating protein 3" O43295 3 8980591-9363053 "Disease related genes, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Ependymal cells: 490.3;Prostatic hillock cells: 690.7;Renal collecting duct principal cells: 462.3;Retinal amacrine cells: 897.2" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 690.7;Neuronal cells: 897.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 8.0" "Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary gland ductal cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 13565677.6;Fallopian tube cells: 5193602.0;Microglia and Neuropil: 19860378.1;Neurons: 18859862.3" "Tissue enriched" "Detected in some" "cerebral cortex: 27658730.6" "HPA036959, HPA044074, HPA078079" Enhanced Approved "Centrosome,Basal body,Cytosol" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 2: Neurons - Nucleosome" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 Cytosol "Centrosome, Basal body" "HPA036959: , HPA044074: , HPA078079: " "unprognostic (5.24e-3)" "unprognostic (3.39e-2)" "unprognostic (2.66e-1)" "unprognostic (7.71e-2)" "unprognostic (1.49e-1)" "unprognostic (1.93e-1)" "unprognostic (3.98e-2)" "unprognostic (2.93e-1)" "unprognostic (2.40e-2)" "unprognostic (2.19e-2)" "unprognostic (3.82e-3)" "unprognostic (2.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.08e-2)" "unprognostic (2.59e-2)" "unprognostic (2.83e-3)" "unprognostic (3.66e-1)" "unprognostic (3.66e-2)" "unprognostic (1.25e-2)" "unprognostic (4.56e-2)" "unprognostic (2.27e-2)" "unprognostic (2.52e-1)" "unprognostic (6.37e-2)" "unprognostic (8.35e-2)" SRI ENSG00000075142 Sorcin P30626 7 88205115-88226993 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 529.7" "Cell type enhanced" "Detected in all" "Colonocytes: 1442.1;Enteric transient amplifying cells: 605.0;Enterocytes: 1216.4;Extravillous trophoblasts: 2163.8;Fallopian tube ciliated cells: 593.9;Respiratory ciliated cells: 618.7" "Cell type enhanced" "Detected in all" "Enterocytes: 1442.1;Trophoblast cells: 2163.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA019004, HPA073666" Enhanced Approved Nucleoplasm,Cytosol No No 1300000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 17: Intestine - Digestion" "Cluster 21: Non-specific - Metabolism" "Cluster 39: Non-specific - Transcription" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 15 "Nucleoplasm, Cytosol" "HPA019004: , HPA073666: " "unprognostic (4.91e-2)" "unprognostic (2.02e-1)" "unprognostic (1.40e-1)" "unprognostic (2.09e-3)" "unprognostic (3.05e-2)" "unprognostic (9.81e-2)" "unprognostic (1.00e-1)" "unprognostic (2.33e-1)" "potential prognostic unfavorable (9.65e-4)" "unprognostic (3.45e-2)" "potential prognostic favorable (3.24e-5)" "unprognostic (2.43e-1)" "unprognostic (2.09e-2)" "validated prognostic unfavorable (2.63e-4)" "validated prognostic unfavorable (1.85e-4)" "unprognostic (1.36e-1)" "unprognostic (9.07e-3)" "unprognostic (3.65e-2)" "potential prognostic unfavorable (6.67e-4)" "unprognostic (9.79e-2)" "unprognostic (3.85e-2)" "unprognostic (1.44e-3)" "unprognostic (3.30e-1)" "unprognostic (8.28e-2)" "unprognostic (8.69e-2)" "unprognostic (1.76e-1)" "unprognostic (2.26e-1)" "unprognostic (3.20e-3)" "unprognostic (8.39e-3)" "unprognostic (3.96e-2)" "unprognostic (2.69e-1)" SRMS "C20orf148, dJ697K14.1, PTK70, SRM" ENSG00000125508 "Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites" Q9H3Y6 20 63538489-63547749 "Enzymes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.0;lymphoid tissue: 2.1;stomach 1: 2.1" "Cell type enhanced" "Detected in some" "Breast hormone-responsive cells: 4.1;Breast lactating cells: 12.2;Epididymal principal cells: 10.3;Foveolar cells: 9.0;Gastric chief cells: 19.7;Goblet cells: 15.7;Mucous neck cells: 9.0" "Cell type enhanced" "Detected in some" "Gastric glandular cells: 19.7;Goblet cells: 15.7;Reproductive supporting cells: 10.3;Secretory cells: 12.2" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 11.7;Gastric cancer: 8.7" "Breast - Breast glandular cells, Skin - Hair cortex cells, Skin - Inner root sheath cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB044668, CAB044669, HPA073987" Uncertain Approved "Intermediate filaments,Actin filaments,Cytosol" No NA "Cluster 60: Stomach - Digestion" "Cluster 6: Non-specific - Immune response" "Cluster 7: Liver cancer - Metabolism" "Cluster 70: Intestinal goblet cells - Mucin production" 21 "Intermediate filaments" "Actin filaments, Cytosol" "CAB044668: , CAB044669: , HPA073987: " "unprognostic (6.29e-3)" "unprognostic (1.58e-2)" "unprognostic (1.96e-1)" "unprognostic (1.47e-2)" "unprognostic (2.92e-2)" "unprognostic (6.13e-2)" "unprognostic (1.73e-1)" "unprognostic (1.21e-2)" "unprognostic (5.69e-3)" "unprognostic (5.72e-2)" "unprognostic (7.49e-2)" "unprognostic (7.43e-3)" "unprognostic (1.69e-1)" "unprognostic (1.80e-3)" "unprognostic (1.94e-1)" "unprognostic (1.33e-1)" SRP14 "ALURBP, MGC14326" ENSG00000140319 "Signal recognition particle 14" P37108 15 40035690-40039181 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial luminal cells: 2197.7;Esophageal apical cells: 2561.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA053738, HPA065118" Approved Nucleoplasm,Nucleoli NA NA 59000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 58: Non-specific - Nuclear processes" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 165 Nucleoli Nucleoplasm "HPA053738: , HPA065118: " "unprognostic (3.02e-3)" "unprognostic (7.14e-2)" "unprognostic (6.49e-2)" "unprognostic (7.55e-3)" "unprognostic (3.20e-2)" "unprognostic (2.75e-1)" "unprognostic (6.45e-2)" "unprognostic (2.65e-1)" "unprognostic (3.04e-2)" "unprognostic (1.78e-2)" "potential prognostic favorable (9.05e-6)" "unprognostic (5.41e-3)" "unprognostic (1.11e-1)" "unprognostic (1.78e-2)" "unprognostic (6.01e-3)" "unprognostic (7.99e-3)" "unprognostic (2.62e-1)" "unprognostic (3.15e-3)" "unprognostic (1.48e-1)" "unprognostic (1.48e-1)" "unprognostic (8.98e-2)" "unprognostic (1.89e-1)" "unprognostic (9.52e-2)" "unprognostic (4.77e-2)" "unprognostic (1.81e-1)" "unprognostic (1.92e-1)" "unprognostic (1.66e-1)" "unprognostic (9.42e-2)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (1.98e-3)" SRPK2 SFRSK2 ENSG00000135250 "SRSF protein kinase 2" P78362 7 105110704-105399308 "Enzymes, Predicted intracellular proteins" "Differentiation, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 87.6" "Cell type enhanced" "Detected in all" "Early spermatids: 1649.0;Late spermatids: 3787.4;Neutrophils: 2230.6;Sertoli cells: 1647.0" "Group enriched" "Detected in all" 4 "Neutrophils: 2230.6;Reproductive supporting cells: 1647.0;Spermatogenic cell types: 3787.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 29635598.5" "Tissue enhanced" "Detected in many" "cerebral cortex: 4862907.9" "HPA015522, HPA020876" Enhanced Supported "Nucleoplasm,Nucleoli,Cytosol,Acrosome,End piece" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 245 "Nucleoplasm, Cytosol" "Nucleoli, Acrosome, End piece" "HPA015522: , HPA020876: " "unprognostic (1.76e-2)" "unprognostic (1.29e-2)" "unprognostic (6.75e-3)" "unprognostic (1.51e-2)" "unprognostic (3.39e-2)" "unprognostic (3.61e-2)" "unprognostic (3.21e-1)" "unprognostic (3.47e-2)" "unprognostic (2.31e-1)" "potential prognostic unfavorable (3.02e-5)" "potential prognostic favorable (8.81e-5)" "unprognostic (1.12e-1)" "unprognostic (2.31e-1)" "unprognostic (4.81e-2)" "unprognostic (1.50e-2)" "unprognostic (2.22e-2)" "unprognostic (1.68e-1)" "unprognostic (2.33e-1)" "unprognostic (1.05e-1)" "unprognostic (2.50e-2)" "unprognostic (5.34e-2)" "unprognostic (5.02e-2)" "potential prognostic unfavorable (9.25e-4)" "unprognostic (1.77e-1)" "unprognostic (4.08e-2)" "unprognostic (2.20e-1)" "unprognostic (6.96e-2)" "unprognostic (4.53e-1)" "unprognostic (4.88e-2)" "unprognostic (4.84e-2)" "unprognostic (1.67e-1)" SRR "ILV1, ISO1" ENSG00000167720 "Serine racemase" Q9GZT4 17 2303383-2325260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Allosteric enzyme, Isomerase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cardiomyocytes: 103.2;Early primary spermatocytes: 44.4;Epicardial cells: 161.5" "Group enriched" "Detected in many" 4 "Barrier epithelial cells: 161.5;Myocytes: 103.2;Spermatogenic cell types: 44.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "heart muscle: 1528630.5" "HPA007529, CAB015343" Approved Approved Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 40: Non-specific - Mixed function" "Cluster 39: Astrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 6 Vesicles "CAB015343: , HPA007529: " "unprognostic (5.61e-2)" "unprognostic (3.71e-2)" "unprognostic (3.43e-2)" "unprognostic (3.92e-2)" "unprognostic (9.38e-2)" "unprognostic (1.51e-2)" "unprognostic (3.01e-1)" "unprognostic (3.41e-1)" "unprognostic (9.57e-3)" "unprognostic (6.54e-2)" "potential prognostic favorable (4.44e-5)" "unprognostic (1.01e-3)" "unprognostic (5.54e-3)" "unprognostic (5.01e-2)" "unprognostic (3.50e-1)" "unprognostic (1.08e-2)" "unprognostic (6.97e-2)" "unprognostic (6.50e-3)" "unprognostic (6.22e-2)" "unprognostic (2.15e-2)" "unprognostic (2.85e-1)" "unprognostic (1.94e-2)" "unprognostic (1.34e-2)" "unprognostic (2.98e-2)" "unprognostic (2.84e-1)" "unprognostic (4.12e-3)" "unprognostic (3.17e-2)" "unprognostic (3.12e-2)" "unprognostic (9.25e-2)" "unprognostic (6.44e-2)" "unprognostic (3.21e-2)" SRRM5 ENSG00000226763 "Serine/arginine repetitive matrix 5" B3KS81 19 43596617-43614498 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 45.0" "Cell type enhanced" "Detected in many" "Adipocytes: 22.3;Cardiomyocytes: 111.3;Early spermatids: 244.5;Epicardial cells: 38.7;Late spermatids: 84.2" "Group enriched" "Detected in many" 4 "Myocytes: 111.3;Spermatogenic cell types: 244.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Prostate Adenocarcinoma (TCGA): 4.5;Uterine Corpus Endometrial Carcinoma (TCGA): 12.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047399, HPA052924" Uncertain Approved Vesicles,Centrosome NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Vesicles Centrosome "HPA047399: , HPA052924: " "unprognostic (4.60e-3)" "unprognostic (8.72e-2)" "unprognostic (4.10e-1)" "unprognostic (1.00e-1)" "unprognostic (1.58e-2)" "unprognostic (1.50e-2)" "potential prognostic favorable (1.68e-4)" "unprognostic (3.70e-2)" "unprognostic (2.41e-1)" "unprognostic (1.53e-1)" "unprognostic (1.84e-1)" SRSF2 "PR264, SC-35, SC35, SFRS2, SFRS2A" ENSG00000161547 "Serine and arginine rich splicing factor 2" Q01130 17 76734115-76737333 "Cancer-related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 680.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" HPA049905 Supported Approved Nucleoplasm,Cytosol NA NA 53000 "Cluster 13: Non-specific - Mitochondria" "Cluster 49: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 34 Nucleoplasm Cytosol "HPA049905: " "unprognostic (1.19e-1)" "unprognostic (2.94e-1)" "unprognostic (7.54e-2)" "unprognostic (2.78e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-1)" "unprognostic (6.03e-2)" "unprognostic (6.55e-2)" "unprognostic (1.03e-2)" "unprognostic (1.54e-1)" "unprognostic (1.13e-2)" "unprognostic (2.04e-2)" "validated prognostic unfavorable (1.96e-4)" "validated prognostic unfavorable (2.35e-4)" "unprognostic (1.36e-2)" "unprognostic (4.86e-2)" "unprognostic (2.07e-1)" "potential prognostic favorable (1.71e-4)" "unprognostic (8.81e-2)" "unprognostic (1.41e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-3)" "unprognostic (4.67e-2)" "unprognostic (1.84e-1)" "unprognostic (3.92e-2)" "unprognostic (2.07e-1)" "unprognostic (7.07e-3)" "unprognostic (2.88e-1)" SRSF6 "B52, SFRS6, SRP55" ENSG00000124193 "Serine and arginine rich splicing factor 6" Q13247 20 43457893-43466046 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 81.2;Bergmann glia: 89.6;Brain excitatory neurons: 51.2;Brain inhibitory neurons: 52.9;Choroid plexus epithelial cells: 81.2;Distal convoluted tubule cells: 49.8;Ependymal cells: 49.9;Loop of henle epithelial cells: 43.4;Microglia: 61.7;Oligodendrocyte progenitor cells: 130.2;Oligodendrocytes: 103.2;Other brain neurons: 51.0;Platelets: 42.2;Podocytes: 46.5;Proximal tubule cells: 57.6;Renal collecting duct intercalated cells: 52.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 81.2;Ductal cells: 52.0;Glial cells: 130.2;Neuronal cells: 52.9;Renal nephron cells: 57.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "bone marrow: 29009615.3" "HPA029005, CAB034889" Supported Supported "Nuclear speckles" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 62: Non-specific - Plasma proteins" "Cluster 98: Neurons - Neurotransmission & signaling" 77 "Nuclear speckles" "CAB034889: , HPA029005: " "unprognostic (1.52e-1)" "unprognostic (6.10e-2)" "unprognostic (2.63e-1)" "unprognostic (8.96e-2)" "unprognostic (3.96e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (2.60e-1)" "unprognostic (1.33e-2)" "unprognostic (1.98e-1)" "unprognostic (1.11e-1)" "unprognostic (8.67e-2)" "unprognostic (2.37e-2)" "unprognostic (1.75e-1)" "unprognostic (1.90e-1)" "unprognostic (3.02e-1)" "unprognostic (1.53e-1)" "potential prognostic favorable (1.96e-4)" "unprognostic (5.71e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-3)" "unprognostic (1.38e-2)" "unprognostic (2.51e-2)" "unprognostic (8.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.32e-1)" "unprognostic (2.72e-2)" "unprognostic (6.58e-2)" "unprognostic (4.24e-1)" SRSF8 "SFRS2B, SRP46" ENSG00000263465 "Serine and arginine rich splicing factor 8" Q9BRL6 11 95066919-95071225 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 242.2" "Cell type enhanced" "Detected in all" "Platelets: 242.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Not detected" "Not detected" "Tissue enriched" "Detected in some" "lymphoid tissue: 102927.7" HPA049905 Supported Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 33: Thyroid gland - Tissue development" "Cluster 31: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 15 Nucleoplasm Cytosol "HPA049905: " "unprognostic (1.89e-3)" "unprognostic (4.13e-3)" "unprognostic (7.16e-2)" "unprognostic (4.11e-1)" "unprognostic (1.50e-2)" "unprognostic (1.21e-1)" "unprognostic (2.56e-1)" "unprognostic (3.33e-2)" "potential prognostic favorable (1.05e-9)" "unprognostic (4.29e-3)" "unprognostic (2.44e-3)" "unprognostic (2.63e-1)" "unprognostic (2.04e-2)" "unprognostic (2.26e-1)" "unprognostic (1.84e-1)" "unprognostic (2.45e-1)" "unprognostic (3.75e-1)" "unprognostic (1.78e-1)" "unprognostic (2.80e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-2)" "unprognostic (5.79e-2)" "unprognostic (5.78e-2)" "unprognostic (1.88e-1)" "unprognostic (1.62e-1)" "unprognostic (5.94e-2)" "unprognostic (3.15e-2)" SRSF9 "SFRS9, SRp30c" ENSG00000111786 "Serine and arginine rich splicing factor 9" Q13242 12 120461672-120495946 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 485.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 49752237.5" "Tissue enhanced" "Detected in all" "ovary: 172582549.0" HPA049849 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 58 Nucleoplasm Nucleoli "HPA049849: " "unprognostic (1.42e-2)" "unprognostic (5.69e-2)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (1.31e-1)" "potential prognostic favorable (7.21e-4)" "unprognostic (3.21e-3)" "unprognostic (2.32e-2)" "unprognostic (4.82e-3)" "unprognostic (8.71e-3)" "unprognostic (1.46e-1)" "validated prognostic unfavorable (4.00e-7)" "validated prognostic unfavorable (1.25e-5)" "unprognostic (1.14e-3)" "unprognostic (6.46e-3)" "unprognostic (1.07e-1)" "unprognostic (1.76e-2)" "unprognostic (1.86e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (5.58e-2)" "unprognostic (5.14e-2)" "unprognostic (6.01e-2)" "unprognostic (1.43e-1)" "unprognostic (5.68e-2)" "unprognostic (5.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.74e-1)" "unprognostic (1.03e-3)" SS18L2 KIAA-iso ENSG00000008324 "SS18 like 2" Q9UHA2 3 42581840-42596934 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 217517.7;Macrophages: 223749.7;T-cells: 169678.3" "Group enriched" "Detected in some" 7601 "bone marrow: 930350.6;lymphoid tissue: 589760.9" HPA047377 Approved Approved Nucleoplasm,Nucleoli,Mitochondria Yes No "Cluster 39: T-cells - T-cell receptor" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 100: Stratified epithelial cells - Barrier functions" 22 "Nucleoli, Mitochondria" Nucleoplasm "HPA047377: " "unprognostic (7.92e-2)" "unprognostic (6.98e-3)" "unprognostic (1.23e-2)" "unprognostic (2.36e-2)" "unprognostic (2.56e-1)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (2.07e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.12e-5)" "unprognostic (5.42e-3)" "unprognostic (3.29e-3)" "unprognostic (2.53e-2)" "validated prognostic unfavorable (4.76e-4)" "validated prognostic unfavorable (2.50e-6)" "unprognostic (4.91e-3)" "unprognostic (3.46e-2)" "unprognostic (5.15e-3)" "unprognostic (2.29e-1)" "unprognostic (1.75e-1)" "unprognostic (1.19e-1)" "unprognostic (9.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.54e-2)" "unprognostic (2.99e-2)" "unprognostic (4.90e-3)" "unprognostic (8.63e-2)" "unprognostic (7.36e-2)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (2.05e-1)" SSBP2 HSPC116 ENSG00000145687 "Single stranded DNA binding protein 2" P81877 5 81412804-81751797 "Predicted intracellular proteins, Predicted membrane proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hematopoietic stem cells: 1661.4;Pituicytes/FSCs: 1401.6;Thymocytes: 2186.0" "Cell type enhanced" "Detected in all" "T-cells: 2186.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1977444.6" "Group enriched" "Detected in some" 12385 "fallopian tube: 1106046.7;ovary: 1370880.1" "CAB020834, HPA068605, HPA071780" Approved Enhanced Nucleoplasm NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 63 Nucleoplasm "CAB020834: , HPA068605: , HPA071780: " "unprognostic (1.26e-1)" "unprognostic (6.57e-3)" "potential prognostic unfavorable (6.92e-4)" "unprognostic (3.89e-3)" "unprognostic (1.21e-1)" "unprognostic (6.24e-2)" "unprognostic (6.11e-2)" "unprognostic (3.53e-3)" "unprognostic (5.73e-2)" "unprognostic (1.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.29e-1)" "unprognostic (2.08e-1)" "unprognostic (7.49e-3)" "unprognostic (1.20e-1)" "unprognostic (4.14e-2)" "unprognostic (1.66e-1)" "unprognostic (1.59e-1)" "unprognostic (3.11e-2)" "unprognostic (1.52e-2)" "unprognostic (6.80e-2)" "unprognostic (2.91e-3)" "unprognostic (7.90e-3)" "unprognostic (3.09e-1)" "potential prognostic unfavorable (3.41e-5)" "unprognostic (7.75e-2)" "unprognostic (1.95e-1)" "unprognostic (8.09e-3)" "unprognostic (1.72e-1)" "unprognostic (7.26e-2)" "unprognostic (6.23e-2)" SSC5D "FLJ35258, S5D-SRCRB" ENSG00000179954 "Scavenger receptor cysteine rich family member with 5 domains" A1L4H1 19 55488404-55519099 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 77.3;Decidual stromal cells: 34.1;Endometrial stromal cells: 24.5;Fibro-adipogenic progenitors: 43.6;Fibroblasts: 30.0;Hepatic stellate cells: 51.6;Lactotrophs: 31.3;Leydig cells: 25.8;Myosatellite cells: 20.8;Peritubular myoid cells: 22.4;Schwann cells: 23.4;Smooth muscle cells: 28.4" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 43.6;Pituitary endocrine cells: 77.3;Stellate cells: 51.6" "Cell type enhanced" "Detected in many" "fibroblast: 40.1;pericyte: 23.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 13.1" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Breast - Fibroblasts, Heart muscle - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Fibroblasts_1, Spleen - Fibroblasts_2, Stomach - Fibroblasts, Testis - Peritubular cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Smooth muscle cells: 3796352.7" "Low tissue specificity" "Detected in many" "HPA042008, HPA053316" Approved Approved Nucleoplasm,Cytosol "Secreted in other tissues" Receptor Yes NA 48000000 "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 6: Non-specific - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 15 "Nucleoplasm, Cytosol" "HPA042008: , HPA053316: " "unprognostic (6.76e-3)" "unprognostic (1.22e-1)" "unprognostic (3.51e-2)" "unprognostic (9.69e-2)" "unprognostic (1.29e-2)" "unprognostic (3.42e-1)" "unprognostic (7.94e-2)" "unprognostic (5.31e-2)" "unprognostic (3.59e-3)" "potential prognostic unfavorable (8.93e-4)" "unprognostic (1.92e-3)" "unprognostic (1.51e-1)" "unprognostic (2.42e-3)" "unprognostic (2.19e-1)" "unprognostic (7.29e-2)" "unprognostic (4.54e-2)" "unprognostic (6.05e-2)" "potential prognostic unfavorable (8.08e-4)" "unprognostic (2.28e-2)" "unprognostic (6.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.89e-2)" "unprognostic (3.34e-2)" "unprognostic (7.12e-2)" "unprognostic (6.64e-2)" "unprognostic (2.42e-2)" "unprognostic (1.44e-1)" "unprognostic (1.44e-3)" "unprognostic (4.44e-3)" SSNA1 "N14, NA14" ENSG00000176101 "SS nuclear autoantigen 1" O43805 9 137188660-137190370 "Predicted intracellular proteins" "Cell cycle, Cell division, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 471.7;Esophageal basal cells: 293.1;Esophageal suprabasal cells: 357.9;Late primary spermatocytes: 426.4" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 471.7;Spermatogenic cell types: 426.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 1897430.9;Oocytes: 788044.6" "Tissue enriched" "Detected in many" "heart muscle: 13749274.9" HPA074006 Approved "Nucleoplasm,Vesicles,Basal body,Cytosol" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 97: Non-specific - Cellular respiration" 19 "Nucleoplasm, Basal body" "Vesicles, Cytosol" "HPA074006: " "unprognostic (2.77e-2)" "unprognostic (2.49e-2)" "unprognostic (9.31e-3)" "unprognostic (6.95e-2)" "unprognostic (1.20e-2)" "unprognostic (3.42e-3)" "unprognostic (6.97e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-2)" "unprognostic (1.32e-2)" "unprognostic (2.50e-2)" "unprognostic (8.54e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (8.51e-4)" "unprognostic (4.35e-3)" "unprognostic (9.59e-2)" "unprognostic (1.21e-1)" "unprognostic (3.44e-2)" "unprognostic (1.67e-1)" "unprognostic (1.84e-1)" "unprognostic (1.16e-1)" "unprognostic (2.71e-1)" "unprognostic (2.02e-1)" "unprognostic (3.04e-1)" "unprognostic (2.09e-2)" "unprognostic (2.79e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (2.04e-2)" "unprognostic (6.13e-2)" "unprognostic (6.53e-2)" SSPN "KRAG, SPN1, SPN2" ENSG00000123096 Sarcospan Q14714 12 26121991-26299290 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 73.7" "Cell type enhanced" "Detected in many" "B-cells: 152.0;Breast myoepithelial cells: 196.3;Epicardial cells: 163.7;Leydig cells: 139.7;Peritubular myoid cells: 248.5;Plasma cells: 132.0;Smooth muscle cells: 165.4;Thymic myoid cells: 296.4" "Cell type enhanced" "Detected in many" "Stromal cells: 296.4" "Cell type enhanced" "Detected in all" "astrocyte: 122.1;ependymal cell: 139.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "memory B-cell: 57.7;naive B-cell: 17.1" "Lineage enriched" "Detected in many" 19 "B-cells: 57.7" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Liver - Hepatic stellate cells, Minor Salivary Gland - Fibroblasts, Prostate - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Capillaries: 7385703.6;Cardiomyocytes: 6453064.7;Skeletal myofibers: 10778646.8;Smooth muscle cells: 5875976.3" "Group enriched" "Detected in many" "blood vessel: 1424159.4;heart muscle: 5147316.8;skeletal muscle: 4349515.7" HPA066432 Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 17: B-cells - Immunoglobulins" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 39: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 94: Gonadal somatic cells - Mixed function" "Nuclear membrane" Nucleoplasm "HPA066432: " "potential prognostic favorable (2.81e-5)" "unprognostic (5.25e-3)" "unprognostic (1.79e-1)" "unprognostic (7.97e-2)" "unprognostic (1.32e-1)" "unprognostic (1.15e-1)" "unprognostic (5.49e-1)" "potential prognostic unfavorable (3.61e-5)" "unprognostic (4.97e-2)" "unprognostic (1.43e-1)" "validated prognostic favorable (7.84e-4)" "validated prognostic favorable (4.98e-6)" "unprognostic (5.07e-2)" "unprognostic (9.92e-2)" "unprognostic (5.26e-2)" "unprognostic (4.59e-2)" "unprognostic (6.37e-3)" "unprognostic (3.69e-3)" "unprognostic (6.19e-2)" "unprognostic (1.64e-1)" "unprognostic (7.23e-3)" "unprognostic (1.31e-2)" "unprognostic (1.21e-1)" "unprognostic (8.03e-2)" "unprognostic (2.40e-2)" "unprognostic (2.50e-1)" "unprognostic (1.41e-3)" "unprognostic (3.93e-2)" "unprognostic (1.11e-1)" "unprognostic (6.26e-2)" SSU72 HSPC182 ENSG00000160075 "SSU72 homolog, RNA polymerase II CTD phosphatase" Q9NP77 1 1541673-1574863 "Enzymes, Essential proteins, Predicted intracellular proteins" "mRNA processing" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 821.9;Esophageal suprabasal cells: 443.1;Late spermatids: 1130.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 821.9;Spermatogenic cell types: 1130.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "lymphoid tissue: 1956306.7;ovary: 2254438.0" "HPA069290, HPA070604" Supported Approved Nucleoplasm,Cytosol No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 85: Squamous epithelial cells - Keratinization" 11 "Nucleoplasm, Cytosol" "HPA069290: , HPA070604: " "unprognostic (4.36e-1)" "unprognostic (1.61e-1)" "unprognostic (4.65e-2)" "unprognostic (3.58e-1)" "unprognostic (2.07e-1)" "unprognostic (2.21e-1)" "unprognostic (1.08e-1)" "unprognostic (4.01e-1)" "unprognostic (8.31e-2)" "unprognostic (6.09e-3)" "potential prognostic favorable (7.38e-4)" "unprognostic (4.90e-3)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (1.11e-5)" "unprognostic (2.68e-3)" "unprognostic (3.01e-2)" "unprognostic (2.38e-2)" "unprognostic (2.70e-1)" "unprognostic (2.08e-1)" "unprognostic (9.43e-2)" "unprognostic (3.80e-2)" "unprognostic (3.68e-2)" "unprognostic (5.23e-2)" "unprognostic (3.98e-1)" "unprognostic (1.54e-2)" "unprognostic (2.71e-2)" "unprognostic (2.98e-1)" "unprognostic (2.21e-1)" "unprognostic (6.96e-2)" "unprognostic (8.78e-2)" "unprognostic (4.85e-2)" SSX1 CT5.1 ENSG00000126752 "SSX family member 1" Q16384 X 48255392-48267444 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 20 "testis: 6.9" "Group enriched" "Detected in some" 5 "Differentiating spermatogonia: 20.6;Early primary spermatocytes: 38.0" "Cell type enriched" "Detected in single" 133 "Spermatogenic cell types: 38.0" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 11.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Myeloma: 50.5" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 3: Early primary spermatocytes - Early meiosis" 4 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (3.30e-1)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (2.15e-3)" "unprognostic (1.03e-1)" "unprognostic (1.62e-1)" "unprognostic (3.41e-2)" "unprognostic (1.10e-2)" "unprognostic (1.05e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" SSX2 "CT5.2a, HD21, HOM-MEL-40, MGC119055, MGC15364, MGC3884, SSX" ENSG00000241476 "SSX family member 2" Q16385 X 52696896-52707178 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 52 "testis: 15.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 41.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Enhanced Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" 15 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " SSX2B CT5.2b ENSG00000268447 "SSX family member 2B" Q16385 X 52751132-52790305 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 51 "testis: 15.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 41.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 44: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 80: Oligodendrocytes - Myelination" 9 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (2.36e-1)" "potential prognostic unfavorable (4.40e-4)" "unprognostic (2.93e-2)" "unprognostic (7.20e-3)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (6.08e-4)" SSX2IP hMsd1 ENSG00000117155 "SSX family member 2 interacting protein" Q9Y2D8 1 84643706-84690803 "Predicted intracellular proteins" "Cell adhesion, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 109.9;testis: 98.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 345.7;Early spermatids: 958.1;Late primary spermatocytes: 306.0;Late spermatids: 1688.0;Megakaryocytes: 216.4;Platelets: 540.4;Rod photoreceptor cells: 273.4" "Cell type enhanced" "Detected in many" "Platelets: 540.4;Spermatogenic cell types: 1688.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Pituitary gland - Corticotropes, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 147935.8;Neurons: 170409.0" "Tissue enriched" "Detected in single" 822 "cerebral cortex: 82204.5" "HPA027306, HPA075946" Supported Supported "Centriolar satellite,Centrosome,Basal body,Acrosome,Equatorial segment,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 42: Retina - Visual perception" "Cluster 53: Neurons - Mixed function" "Cluster 65: Non-specific - Unknown function" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 125 "Centriolar satellite, Centrosome, Basal body" "Acrosome, Equatorial segment, Principal piece" "HPA027306: , HPA075946: " "unprognostic (3.18e-1)" "unprognostic (3.89e-2)" "unprognostic (8.20e-2)" "unprognostic (1.99e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (5.98e-2)" "unprognostic (1.97e-1)" "unprognostic (4.44e-2)" "unprognostic (7.83e-2)" "unprognostic (1.48e-3)" "unprognostic (8.90e-3)" "unprognostic (1.71e-1)" "unprognostic (5.98e-3)" "unprognostic (5.49e-3)" "unprognostic (3.11e-2)" "unprognostic (2.41e-3)" "unprognostic (1.75e-2)" "unprognostic (3.48e-1)" "unprognostic (1.18e-1)" "unprognostic (5.09e-2)" "unprognostic (1.18e-1)" "unprognostic (2.52e-1)" "unprognostic (5.94e-2)" "unprognostic (3.54e-1)" "unprognostic (1.03e-3)" "unprognostic (6.51e-3)" "unprognostic (2.09e-1)" "unprognostic (6.24e-2)" "unprognostic (8.52e-3)" "unprognostic (6.22e-2)" "unprognostic (8.68e-2)" SSX3 CT5.3 ENSG00000165584 "SSX family member 3" Q99909 X 48346427-48356707 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 60 "testis: 12.0" "Group enriched" "Detected in some" 8 "Differentiating spermatogonia: 178.2;Early primary spermatocytes: 136.0" "Cell type enriched" "Detected in single" 267 "Spermatogenic cell types: 178.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Liver Hepatocellular Carcinoma (TCGA): 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "prostate cancer: 19.2" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 13 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "potential prognostic unfavorable (3.65e-4)" SSX4 CT5.4 ENSG00000268009 "SSX family member 4" O60224 X 48383516-48393347 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Ovary Serous Cystadenocarcinoma (TCGA): 5.2;Stomach Adenocarcinoma (TCGA): 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 11.6;lymphoma: 5.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 53: Squamous epithelial cells - Keratinization" 4 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (2.65e-2)" "potential prognostic unfavorable (6.84e-6)" "unprognostic (1.09e-1)" "unprognostic (1.71e-1)" "unprognostic (4.98e-3)" SSX4B OTTHUMT00000056510 ENSG00000269791 "SSX family member 4B" O60224 X 48402082-48411960 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 9 "testis: 1.3" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Ovary Serous Cystadenocarcinoma (TCGA): 1.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Bladder cancer: 4.3;lymphoma: 4.6;Myeloma: 9.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 47: Testis - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" 2 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (8.84e-2)" SSX5 ENSG00000165583 "SSX family member 5" O60225 X 48186220-48196795 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 4.3;Early primary spermatocytes: 5.2" "Cell type enriched" "Detected in some" 4 "Spermatogenic cell types: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 32: Cerebral cortex - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " SSX7 ENSG00000187754 "SSX family member 7" Q7RTT5 X 52644061-52654900 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045683, HPA071685" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 4 "Nucleoplasm, Nucleoli" "HPA045683: , HPA071685: " "unprognostic (1.56e-2)" ST13 "FAM10A1, HIP, HSPABP1, P48, SNC6" ENSG00000100380 "ST13 Hsp70 interacting protein" P50502 22 40824535-40856639 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal efferent duct absorptive cells: 932.4;Late spermatids: 1444.5;Ovarian stromal cells: 975.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1444.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 157282277.2" "Low tissue specificity" "Detected in all" "HPA043233, HPA046412, HPA047114, HPA047116" Enhanced Approved "Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA 8200000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 66: Non-specific - Mitochondria" "Cluster 94: Gonadal somatic cells - Mixed function" 25 Cytosol "Primary cilium, Primary cilium tip, Basal body" "HPA043233: , HPA046412: , HPA047114: , HPA047116: " "unprognostic (1.51e-2)" "unprognostic (6.67e-2)" "unprognostic (8.63e-2)" "unprognostic (1.17e-1)" "unprognostic (1.28e-1)" "unprognostic (5.16e-2)" "unprognostic (8.03e-2)" "unprognostic (7.61e-2)" "unprognostic (3.85e-3)" "unprognostic (2.64e-1)" "validated prognostic favorable (1.14e-12)" "validated prognostic favorable (2.62e-5)" "unprognostic (3.71e-2)" "unprognostic (3.62e-3)" "unprognostic (3.32e-2)" "unprognostic (5.26e-3)" "unprognostic (5.97e-2)" "unprognostic (1.72e-1)" "unprognostic (1.19e-1)" "unprognostic (1.90e-1)" "unprognostic (2.73e-2)" "unprognostic (1.44e-1)" "unprognostic (2.15e-1)" "unprognostic (7.10e-2)" "unprognostic (4.14e-3)" "unprognostic (3.07e-1)" "unprognostic (6.26e-2)" "unprognostic (8.56e-2)" "unprognostic (1.83e-1)" "unprognostic (7.85e-2)" "unprognostic (4.83e-2)" ST14 "CAP3, HAI, MT-SP1, PRSS14, SNC19, TMPRSS14" ENSG00000149418 "ST14 transmembrane serine protease matriptase" Q9Y5Y6 11 130159782-130210362 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes, Disease variant, Hypotrichosis, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 108.0;intestine: 136.4" "Cell type enhanced" "Detected in many" "Colonocytes: 540.5;Endometrial glandular cells: 340.4;Endometrial luminal cells: 312.6;Enterocytes: 446.9;Esophageal apical cells: 546.6;Esophageal suprabasal cells: 306.1;Ocular epithelial cells: 475.3;Salivary ionocytes: 309.1;Urothelial cells: 451.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 546.6;Barrier epithelial cells: 475.3;Enterocytes: 540.5" "Cell type enhanced" "Detected in some" "leukocyte: 3.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "thalamus: 19.4" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 25.1" "Lineage enriched" "Detected in many" 5 "dendritic cells: 25.1" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Breast glandular cells, Colon - Colon enterocytes, Heart muscle - Macrophages, Skeletal muscle - Macrophages, Testis - Late spermatids" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting ducts: 5749690.6;Large ducts: 6335424.4" "Group enriched" "Detected in many" "intestine: 12819303.6;pancreas: 3448333.4;skin: 6380218.8" "HPA047014, HPA056258" Enhanced Approved Nucleoplasm,Vesicles NA NA 1600000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 17: Intestine - Digestion" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 19 "Nucleoplasm, Vesicles" "HPA047014: , HPA056258: " "unprognostic (3.14e-2)" "unprognostic (5.20e-2)" "unprognostic (3.42e-2)" "unprognostic (2.98e-2)" "unprognostic (1.34e-1)" "unprognostic (1.58e-2)" "unprognostic (2.62e-2)" "unprognostic (1.23e-1)" "unprognostic (2.61e-1)" "unprognostic (2.83e-1)" "unprognostic (2.62e-2)" "unprognostic (1.03e-1)" "potential prognostic favorable (1.47e-7)" "unprognostic (2.09e-1)" "unprognostic (4.01e-1)" "unprognostic (5.04e-2)" "unprognostic (1.04e-3)" "unprognostic (1.31e-1)" "unprognostic (4.20e-2)" "unprognostic (3.32e-1)" "unprognostic (4.22e-1)" "unprognostic (2.85e-3)" "unprognostic (3.58e-1)" "unprognostic (2.63e-1)" "unprognostic (2.81e-2)" "unprognostic (1.17e-1)" "unprognostic (2.94e-1)" "unprognostic (4.76e-2)" "unprognostic (3.18e-1)" "unprognostic (5.99e-2)" "unprognostic (2.65e-2)" ST3GAL2 "SIAT4B, ST3GalA.2, ST3GALII" ENSG00000157350 "ST3 beta-galactoside alpha-2,3-sialyltransferase 2" Q16842 16 70375977-70439237 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 371.6;pDCs: 173.6" "Cell type enhanced" "Detected in many" "dendritic cells: 173.6;Neutrophils: 371.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 134 "Neurons: 13410.4" "Tissue enriched" "Detected in single" 116 "lymphoid tissue: 11571.0" HPA017270 Approved Uncertain Vesicles "Intracellular and membrane" Enzyme NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 1 Vesicles "HPA017270: " "unprognostic (4.09e-2)" "unprognostic (1.52e-1)" "unprognostic (4.72e-2)" "unprognostic (1.12e-2)" "unprognostic (1.44e-1)" "unprognostic (1.09e-1)" "unprognostic (1.78e-1)" "unprognostic (1.51e-3)" "unprognostic (7.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.70e-1)" "unprognostic (8.45e-2)" "unprognostic (2.55e-2)" "potential prognostic unfavorable (4.10e-5)" "unprognostic (2.15e-2)" "unprognostic (2.78e-2)" "unprognostic (2.14e-2)" "unprognostic (1.50e-2)" "unprognostic (4.82e-3)" "unprognostic (6.96e-2)" "unprognostic (5.03e-2)" "unprognostic (1.69e-3)" "unprognostic (5.18e-2)" "unprognostic (7.45e-2)" "unprognostic (2.80e-1)" "unprognostic (8.29e-2)" "unprognostic (9.27e-2)" "unprognostic (9.84e-2)" "unprognostic (1.67e-1)" "unprognostic (5.30e-3)" "unprognostic (8.47e-3)" ST6GALNAC1 "SIAT7A, ST6GalNAcI" ENSG00000070526 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 1" Q9NSC7 17 76624761-76643786 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 57.5;intestine: 183.8;stomach 1: 61.3" "Cell type enhanced" "Detected in many" "Colonocytes: 132.7;Conjunctival goblet cells: 133.0;Endometrial ciliated cells: 102.1;Endometrial glandular cells: 103.7;Endometrial secretory cells: 116.7;Enteric transient amplifying cells: 108.4;Esophageal apical cells: 309.6;Goblet cells: 811.2;Parietal cells: 224.5;Respiratory basal cells: 143.0;Respiratory ciliated cells: 125.2;Respiratory deuterosomal cells: 133.7;Respiratory secretory cells: 231.6" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 309.6;Gastric glandular cells: 224.5;Goblet cells: 811.2;Secretory cells: 231.6" "Cell type enriched" "Detected in some" 16 "endothelial cell: 107.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 8.9;naive CD4 T-cell: 3.4" "Lineage enriched" "Detected in single" 33 "T-cells: 8.9" "Cancer enhanced" "Detected in many" "prostate cancer: 16.8" "Colon - Colon enterocytes, Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 5780 "Large ducts: 577980.2" "Group enriched" "Detected in some" 27525 "intestine: 2262583.9;salivary gland: 3242349.5" "HPA014767, HPA014975" Enhanced Approved "Nucleoplasm,Golgi apparatus" NA NA 1300000 "Cluster 31: T-cells - T-cell receptor" "Cluster 17: Intestine - Digestion" "Cluster 47: Endothelial cells - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 70: Intestinal goblet cells - Mucin production" 2 "Golgi apparatus" Nucleoplasm "HPA014767: , HPA014975: " "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (4.62e-2)" "unprognostic (1.20e-3)" "unprognostic (8.00e-2)" "unprognostic (7.34e-3)" "unprognostic (3.84e-2)" "unprognostic (6.05e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (2.67e-2)" "unprognostic (5.68e-2)" "unprognostic (2.86e-1)" "unprognostic (5.87e-2)" "unprognostic (1.37e-1)" "unprognostic (2.94e-2)" "unprognostic (2.09e-1)" "unprognostic (6.14e-3)" "potential prognostic favorable (3.50e-4)" "unprognostic (1.66e-1)" "unprognostic (1.63e-2)" "unprognostic (1.76e-3)" "unprognostic (6.26e-2)" "unprognostic (1.71e-1)" "unprognostic (6.12e-2)" "unprognostic (2.31e-1)" ST6GALNAC5 "MGC3184, SIAT7E, ST6GalNAcV" ENSG00000117069 "ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5" Q9BVH7 1 76867480-77067546 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 338.6;Alveolar cells type 1: 409.2;Brain excitatory neurons: 701.8;Brain inhibitory neurons: 429.3;Corticotrophs: 540.6;Lactotrophs: 525.2;Other brain neurons: 210.9;Pituitary stem cells: 531.7;Retinal amacrine cells: 206.3;Retinal bipolar cells: 464.8;Schwann cells: 251.1;Somatotrophs: 421.4;Thyrotrophs: 845.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 338.6;Alveolar cells: 409.2;Neuronal cells: 701.8;Pituitary endocrine cells: 845.5;Stem cells: 531.7" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 1854.7;hippocampal dentate gyrus: 2450.7" "Cancer enhanced" "Detected in many" "Ovary Serous Cystadenocarcinoma (TCGA): 4.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bile duct cancer: 4.1;Neuroblastoma: 3.0" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Breast - Breast myoepithelial cells, Colon - Enteric glia cells, Pituitary gland - Thyrotropes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "hippocampal formation: 68.3" "Cell type enriched" "Detected in single" 105 "Pancreatic islets: 10522.6" "Tissue enriched" "Detected in single" 86 "blood vessel: 8575.0" "HPA065593, HPA070354" Uncertain Approved Vesicles "Intracellular and membrane" Enzyme NA Yes 15000 "Cluster 73: Brain - Neuronal signaling" "Cluster 51: Neurons - Mixed function" "Cluster 1: Neuronal - Visual perception" "Cluster 35: Neurons - Synaptic function & neurogenesis" Vesicles "HPA065593: , HPA070354: " "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (3.71e-1)" "unprognostic (1.98e-1)" "unprognostic (7.45e-3)" "unprognostic (3.35e-1)" "unprognostic (9.89e-3)" "unprognostic (7.26e-3)" "unprognostic (2.62e-1)" "unprognostic (2.34e-2)" "unprognostic (2.86e-2)" "unprognostic (3.92e-2)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" "unprognostic (1.08e-1)" ST7 "ETS7q, FAM4A, FAM4A1, HELG, RAY1, SEN4, TSG7" ENSG00000004866 "Suppression of tumorigenicity 7" Q9NRC1 7 116953238-117230176 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 182.4;Proximal tubule cells: 355.5;Renal collecting duct intercalated cells: 300.8;Renal connecting tubule cells: 208.9" "Cell type enhanced" "Detected in all" "Ductal cells: 300.8;Renal nephron cells: 355.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Stomach - Chief cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Neurons: 281102.3;Pancreas epithelial cells: 104742.3" "Tissue enriched" "Detected in single" 2077 "salivary gland: 207714.3" "HPA038325, HPA038326" Approved Supported Nucleoplasm,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 22: Epididymis - Mixed function" "Cluster 35: Non-specific - DNA binding" "Cluster 39: Non-specific - Transcription" "Cluster 88: Proximal tubular cells - Transmembrane transport" 26 Nucleoplasm Cytosol "HPA038325: , HPA038326: " "unprognostic (1.57e-1)" "unprognostic (1.37e-1)" "unprognostic (9.76e-3)" "unprognostic (3.00e-1)" "unprognostic (2.12e-1)" "unprognostic (4.59e-3)" "unprognostic (8.58e-2)" "potential prognostic favorable (1.11e-4)" "unprognostic (1.87e-1)" "unprognostic (9.79e-3)" "potential prognostic favorable (2.23e-6)" "unprognostic (3.06e-3)" "unprognostic (1.57e-2)" "unprognostic (1.55e-2)" "unprognostic (4.81e-2)" "unprognostic (9.92e-3)" "unprognostic (2.53e-1)" "unprognostic (8.79e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-2)" "unprognostic (3.49e-2)" "unprognostic (6.48e-2)" "unprognostic (1.78e-1)" "unprognostic (6.48e-2)" "unprognostic (3.48e-2)" "unprognostic (2.47e-1)" "unprognostic (1.19e-1)" "unprognostic (2.71e-1)" "unprognostic (1.64e-1)" "unprognostic (3.23e-2)" "unprognostic (2.66e-1)" ST8SIA2 "HsT19690, SIAT8B, ST8SIA-II, STX" ENSG00000140557 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2" Q92186 15 92393881-92468728 "Predicted secreted proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 3.6;lymphoid tissue: 1.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 9.1;Brain inhibitory neurons: 6.5;Breast myoepithelial cells: 4.3;Cardiomyocytes: 4.7;Epididymal basal cells: 4.8;Epididymal principal cells: 4.3;Müller glia: 5.1;Oocytes: 4.6;Other brain neurons: 9.3;Pituitary stem cells: 6.4;Retinal amacrine cells: 9.9;Retinal ganglion cells: 3.9;Thymic myoid cells: 4.1" "Cell type enhanced" "Detected in many" "Neuronal cells: 9.9;Stem cells: 6.4" "Cell type enhanced" "Detected in many" "lower rhombic lip: 106.6" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "pons: 18.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Myeloma: 7.8;Neuroblastoma: 18.3" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Heart muscle - Cardiomyocytes, Skeletal muscle - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 159 "intestine: 15855.8" "HPA054518, HPA057819" Approved Supported "Nucleoplasm,Golgi apparatus,Cytosol" "Secreted - unknown location" Enzyme NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 49: Hindbrain - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" 7 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA054518: , HPA057819: " "unprognostic (2.28e-1)" "unprognostic (2.80e-2)" "unprognostic (1.17e-1)" "unprognostic (3.60e-3)" "unprognostic (1.91e-1)" "unprognostic (6.28e-2)" ST8SIA3 SIAT8C ENSG00000177511 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3" O43173 18 57352557-57371731 "Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 23.5;pituitary gland: 9.0;retina: 7.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 71.3;Brain inhibitory neurons: 110.9;Corticotrophs: 99.7;Gonadotrophs: 34.5;Lactotrophs: 46.9;Oligodendrocyte progenitor cells: 26.2;Other brain neurons: 59.9;Pancreatic islet cells: 60.4;Retinal amacrine cells: 25.9;Retinal bipolar cells: 25.2;Retinal horizontal cells: 68.1;Somatotrophs: 59.6;Thyrotrophs: 63.8" "Cell type enhanced" "Detected in some" "Neuronal cells: 110.9;Pancreatic islet cells: 60.4;Pituitary endocrine cells: 99.7" "Cell type enhanced" "Detected in many" "medium spiny neuron: 228.0" "Group enriched" "Detected in some" 10 "Glioblastoma Multiforme (TCGA): 1.7;Pancreatic Adenocarcinoma (TCGA): 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 9.4;thyroid cancer: 4.1" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 8127346.6" "Tissue enriched" "Detected in single" 32524 "cerebral cortex: 3252442.4" "HPA063398, HPA066783" Enhanced Supported "Golgi apparatus" No NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" 8 "Golgi apparatus" "HPA063398: , HPA066783: " "unprognostic (1.94e-1)" "potential prognostic favorable (7.23e-4)" "unprognostic (1.49e-2)" "unprognostic (8.43e-2)" ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 5.9;brain: 23.2;parathyroid gland: 5.8" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 84.4;Brain excitatory neurons: 132.8;Brain inhibitory neurons: 76.6;Cardiomyocytes: 107.9;Gonadotrophs: 32.0;Myonuclei: 32.7;Oligodendrocyte progenitor cells: 52.4;Other brain neurons: 29.7;Renal collecting duct intercalated cells: 36.7;Retinal amacrine cells: 47.5" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 84.4;Glial cells: 52.4;Myocytes: 107.9;Neuronal cells: 132.8" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Glioblastoma Multiforme (TCGA): 5.4;Kidney Chromophobe (TCGA): 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "skin cancer: 7.7" "Heart muscle - Cardiomyocytes, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1654 "Neurons: 165368.4" "Not detected" "Not detected" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 30000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 37: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 35: Neurons - Synaptic function & neurogenesis" 29 "Plasma membrane, Midbody" "HPA043813: , HPA046771: " "unprognostic (1.16e-1)" "unprognostic (7.40e-2)" "unprognostic (7.97e-2)" "potential prognostic favorable (6.59e-4)" STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 428.0" "Cell type enhanced" "Detected in many" "Hofbauer cells: 295.1;Kupffer cells: 59.4;Lymphatic endothelial cells: 73.7;Macrophages: 341.7;Microglia: 53.2;monocytes: 173.1;Vascular endothelial cells: 69.9" "Cell type enriched" "Detected in many" 4 "Mononuclear phagocytes: 341.7" "Cell type enriched" "Detected in some" 4 "central nervous system macrophage: 88.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.5;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.5" "Cancer enriched" "Detected in single" 65 "Leukemia: 14.0" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Heart muscle - Macrophages, Kidney - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages, Thyroid gland - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Macrophages: 171528505.7" "Tissue enriched" "Detected in all" "lymphoid tissue: 107027183.8" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 14000000 "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 2 Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: " "unprognostic (8.43e-3)" "unprognostic (1.38e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-1)" "unprognostic (8.95e-2)" "unprognostic (3.71e-2)" "unprognostic (2.52e-2)" "unprognostic (2.28e-2)" "unprognostic (2.41e-1)" "unprognostic (5.83e-2)" "potential prognostic unfavorable (1.15e-5)" "unprognostic (1.80e-2)" "unprognostic (1.49e-1)" "potential prognostic unfavorable (7.13e-4)" "potential prognostic favorable (8.93e-4)" "unprognostic (5.75e-2)" "unprognostic (2.24e-3)" "unprognostic (1.26e-1)" "unprognostic (5.00e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (1.68e-2)" "unprognostic (1.01e-1)" "unprognostic (9.81e-2)" "unprognostic (5.20e-1)" "unprognostic (2.11e-3)" "unprognostic (3.83e-1)" "unprognostic (2.50e-2)" "unprognostic (3.42e-2)" "unprognostic (1.20e-1)" "unprognostic (3.69e-1)" STAB2 "DKFZP434E0321, FEEL-2, FELL, HARE, SCARH1, STAB-2" ENSG00000136011 "Stabilin 2" Q8WWQ8 12 103587273-103766719 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 63.4" "Cell type enriched" "Detected in many" 7 "Lymphatic endothelial cells: 229.0" "Cell type enriched" "Detected in many" 7 "Endothelial cells: 229.0" "Cell type enhanced" "Detected in many" "hippocampal CA4: 16.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adipose subcutaneous - Smooth muscle cells, Liver - Sinusoid Endothelial cells, Pituitary gland - Gonadotropes, Stomach - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Macrophages: 135850330.1" "Tissue enriched" "Detected in many" "lymphoid tissue: 84115723.8" "HPA026871, HPA072699" Enhanced Supported Cytosol NA NA 760000 "Cluster 5: Spleen - Immune response" "Cluster 51: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 1 Cytosol "HPA026871: , HPA072699: " "unprognostic (1.06e-1)" "unprognostic (7.67e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (2.89e-2)" "unprognostic (9.48e-3)" "unprognostic (2.44e-1)" STAG1 "SA-1, SA1, SCC3A" ENSG00000118007 "Stromal antigen 1" Q8WVM7 3 136336236-136752403 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Mitosis" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1432.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "pancreas: 28034000.8" "HPA035015, HPA058653" Supported Supported "Nucleoplasm,Nuclear bodies,Primary cilium" No No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 24: Neutrophils - Innate immunity signal integration" 32 Nucleoplasm "Nuclear bodies, Primary cilium" "HPA035015: , HPA058653: " "unprognostic (1.06e-3)" "unprognostic (1.04e-1)" "unprognostic (4.99e-2)" "unprognostic (5.22e-2)" "unprognostic (1.48e-1)" "unprognostic (3.50e-2)" "unprognostic (6.39e-2)" "unprognostic (5.44e-2)" "unprognostic (1.57e-1)" "unprognostic (6.20e-3)" "validated prognostic favorable (9.84e-6)" "validated prognostic favorable (7.03e-4)" "unprognostic (2.03e-1)" "unprognostic (1.51e-2)" "unprognostic (3.19e-2)" "unprognostic (1.13e-2)" "unprognostic (1.64e-1)" "unprognostic (2.57e-1)" "unprognostic (1.17e-1)" "unprognostic (7.60e-3)" "unprognostic (2.28e-3)" "unprognostic (1.01e-2)" "unprognostic (1.14e-3)" "unprognostic (1.33e-1)" "unprognostic (4.90e-2)" "unprognostic (9.72e-3)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (1.52e-1)" "unprognostic (6.57e-2)" "unprognostic (1.83e-1)" STAG2 "SA-2, SA2, SCC3B" ENSG00000101972 "Stromal antigen 2" Q8N3U4 X 123960212-124422664 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Chromosome partition, Meiosis, Mitosis" "Cancer-related genes, Disease variant, Holoprosencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 617.6;Neutrophils: 932.7" "Cell type enhanced" "Detected in all" "Neutrophils: 932.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 22112341.7" "Low tissue specificity" "Detected in many" HPA002857 Supported Supported "Nucleoplasm,Nucleoli,Nucleoli fibrillar center" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 80: Thymus - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 55 "Nucleoplasm, Nucleoli, Nucleoli fibrillar center" "HPA002857: " "unprognostic (1.39e-1)" "unprognostic (3.30e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (6.21e-2)" "unprognostic (2.18e-2)" "unprognostic (4.56e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (1.10e-2)" "potential prognostic favorable (1.30e-6)" "unprognostic (1.27e-2)" "unprognostic (1.04e-1)" "unprognostic (2.42e-2)" "unprognostic (9.77e-3)" "unprognostic (2.29e-1)" "unprognostic (1.47e-2)" "unprognostic (4.06e-2)" "unprognostic (1.55e-1)" "unprognostic (1.83e-1)" "unprognostic (1.15e-2)" "unprognostic (1.61e-1)" "unprognostic (8.14e-3)" "unprognostic (1.80e-1)" "unprognostic (7.60e-3)" "unprognostic (1.01e-1)" "unprognostic (7.29e-2)" "unprognostic (8.63e-2)" "unprognostic (8.67e-2)" "unprognostic (6.64e-2)" "unprognostic (2.97e-1)" STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 228.8;Late spermatids: 211.9" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA035800, HPA035801" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 59 Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: , HPA035801: " "unprognostic (1.01e-2)" "unprognostic (3.54e-2)" "unprognostic (5.43e-2)" "unprognostic (1.77e-2)" "unprognostic (4.14e-2)" "unprognostic (4.00e-1)" "unprognostic (3.62e-2)" "unprognostic (1.14e-2)" "unprognostic (2.44e-2)" "unprognostic (4.65e-2)" "potential prognostic favorable (7.87e-6)" "unprognostic (4.22e-1)" "unprognostic (1.38e-1)" "unprognostic (2.21e-2)" "potential prognostic unfavorable (3.43e-4)" "unprognostic (7.74e-3)" "unprognostic (1.41e-2)" "unprognostic (9.15e-2)" "unprognostic (1.59e-1)" "unprognostic (5.39e-2)" "unprognostic (2.76e-2)" "potential prognostic unfavorable (8.03e-4)" "unprognostic (2.47e-3)" "unprognostic (2.26e-1)" "unprognostic (3.54e-2)" "unprognostic (1.23e-1)" "unprognostic (6.75e-2)" "unprognostic (2.32e-1)" "unprognostic (2.92e-1)" "unprognostic (1.83e-1)" "unprognostic (9.13e-2)" STARD10 "CGI-52, NY-CO-28, PCTP2, SDCCAG28" ENSG00000214530 "StAR related lipid transfer domain containing 10" Q9Y365 11 72754729-72794047 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 710.4" "Group enriched" "Detected in many" 4 "Late spermatids: 703.9;Parietal cells: 226.3" "Group enriched" "Detected in many" 7 "Gastric glandular cells: 226.3;Spermatogenic cell types: 703.9" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 21.3" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "breast cancer: 373.2" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 21473726.0;Pancreas epithelial cells: 18021094.8" "Tissue enhanced" "Detected in all" "liver: 34953721.2" HPA026661 Uncertain Supported Cytosol NA NA 35000 "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 3 Cytosol "HPA026661: " "unprognostic (1.60e-1)" "unprognostic (4.79e-2)" "unprognostic (1.21e-2)" "unprognostic (2.84e-1)" "unprognostic (1.26e-1)" "unprognostic (2.49e-1)" "unprognostic (6.17e-2)" "potential prognostic favorable (8.82e-5)" "unprognostic (1.37e-1)" "unprognostic (1.96e-1)" "validated prognostic favorable (2.62e-5)" "validated prognostic favorable (6.39e-4)" "unprognostic (9.65e-2)" "unprognostic (3.04e-2)" "unprognostic (9.97e-2)" "unprognostic (5.52e-2)" "unprognostic (8.78e-2)" "unprognostic (1.58e-1)" "unprognostic (5.09e-1)" "unprognostic (1.58e-1)" "unprognostic (7.29e-2)" "unprognostic (3.69e-1)" "unprognostic (9.80e-2)" "unprognostic (8.11e-2)" "unprognostic (1.07e-1)" "unprognostic (1.79e-3)" "unprognostic (8.41e-2)" "unprognostic (1.65e-1)" "unprognostic (2.80e-1)" "potential prognostic favorable (9.84e-4)" "unprognostic (1.86e-1)" STARD5 MGC10327 ENSG00000172345 "StAR related lipid transfer domain containing 5" Q9NSY2 15 81309053-81324183 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 49.7;Epicardial cells: 63.7;Esophageal apical cells: 44.3;Esophageal basal cells: 27.4;Esophageal suprabasal cells: 32.4;Goblet cells: 24.4;Hepatocytes: 25.1;Plasma cells: 39.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 44.3;Barrier epithelial cells: 63.7;Stromal cells: 49.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Myeloma: 4.5" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" "Hepatocytes: 1703508.3;Keratinocytes: 2335811.3" "Group enriched" "Detected in many" "intestine: 1778507.6;liver: 1310776.2;skin: 2347008.3;Stomach: 1982674.8" HPA040662 Approved Approved Vesicles,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 58: Skin - Keratinization" "Cluster 5: Non-specific - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 44: Plasma cells - Antibody production & secretion" Vesicles Cytosol "HPA040662: " "unprognostic (3.03e-2)" "unprognostic (8.15e-3)" "unprognostic (7.48e-3)" "unprognostic (4.10e-2)" "unprognostic (2.88e-1)" "unprognostic (1.40e-1)" "unprognostic (9.18e-2)" "unprognostic (1.93e-3)" "unprognostic (4.89e-3)" "unprognostic (8.19e-2)" "potential prognostic favorable (4.38e-6)" "unprognostic (2.91e-3)" "unprognostic (1.13e-1)" "unprognostic (2.56e-1)" "unprognostic (3.70e-1)" "potential prognostic favorable (5.90e-4)" "unprognostic (1.73e-1)" "unprognostic (2.50e-1)" "unprognostic (7.63e-2)" "unprognostic (3.39e-2)" "unprognostic (1.73e-1)" "unprognostic (2.80e-2)" "unprognostic (3.55e-2)" "unprognostic (1.97e-1)" STARD7 GTT1 ENSG00000084090 "StAR related lipid transfer domain containing 7" Q9NQZ5 2 96184859-96208827 "Essential proteins, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Thymic myoid cells: 221.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 7723493.9" "Tissue enhanced" "Detected in many" "intestine: 837592.2" "CAB033965, HPA064958, HPA064978" Supported Approved Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 82: Dendritic cells - Antigen presentation" 2 Mitochondria "CAB033965: , HPA064958: , HPA064978: " "unprognostic (1.39e-1)" "unprognostic (1.29e-2)" "unprognostic (1.29e-1)" "unprognostic (1.80e-1)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" "unprognostic (6.24e-2)" "unprognostic (3.17e-1)" "unprognostic (2.50e-3)" "potential prognostic favorable (1.88e-8)" "unprognostic (5.31e-3)" "unprognostic (2.83e-2)" "unprognostic (2.47e-3)" "potential prognostic unfavorable (2.80e-6)" "unprognostic (4.61e-1)" "unprognostic (2.58e-1)" "unprognostic (1.25e-1)" "unprognostic (7.85e-3)" "unprognostic (1.55e-1)" "unprognostic (3.13e-2)" "unprognostic (3.01e-1)" "unprognostic (1.53e-2)" "unprognostic (4.31e-2)" "unprognostic (3.36e-1)" "unprognostic (1.23e-1)" "unprognostic (3.24e-1)" "unprognostic (1.13e-1)" "unprognostic (1.61e-1)" "unprognostic (3.30e-3)" "unprognostic (1.12e-1)" STING1 "ERIS, FLJ38577, MITA, MPYS, NET23, STING, TMEM173" ENSG00000184584 "Stimulator of interferon response cGAMP interactor 1" Q86WV6 5 139475533-139482935 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autophagy, Host-virus interaction, Immunity, Innate immunity, Ion transport, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Choroid plexus epithelial cells: 26.2;Endometrial secretory cells: 9.1;Hepatic stellate cells: 6.5;Medullary thymic epithelial cells: 7.2;Microglia: 30.7;Papillary tip epithelial cells: 10.6;Renal collecting duct principal cells: 6.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 26.2;Glial cells: 30.7" "Group enriched" "Detected in many" 5 "central nervous system macrophage: 37.4;choroid plexus epithelial cell: 39.6;endothelial cell: 31.2;fibroblast: 31.5;leukocyte: 32.0;pericyte: 60.4;vascular associated smooth muscle cell: 31.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "choroid plexus: 21.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Colon - Endothelial cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 23750705.1;Neutrophils: 41372161.8" "Low tissue specificity" "Detected in many" "HPA038116, HPA038534, CAB080401" Enhanced Supported "Nucleoplasm,Vesicles,Primary cilium,Basal body,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 102: Non-specific - Mixed function" 67 Cytosol "Nucleoplasm, Vesicles, Primary cilium, Basal body" "CAB080401: , HPA038116: , HPA038534: " "unprognostic (1.07e-1)" "unprognostic (1.61e-1)" "unprognostic (3.24e-1)" "unprognostic (9.74e-2)" "unprognostic (2.37e-1)" "unprognostic (1.56e-1)" "unprognostic (2.86e-1)" "unprognostic (2.70e-2)" "unprognostic (2.30e-3)" "unprognostic (5.87e-2)" "unprognostic (7.03e-2)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (1.70e-2)" "unprognostic (8.72e-2)" "unprognostic (2.23e-2)" "unprognostic (3.05e-1)" "unprognostic (2.33e-1)" "unprognostic (1.13e-1)" "unprognostic (2.95e-1)" "unprognostic (6.56e-2)" "unprognostic (3.62e-2)" "unprognostic (6.90e-2)" "unprognostic (2.05e-3)" "unprognostic (6.03e-2)" "unprognostic (1.58e-1)" "unprognostic (4.73e-2)" "unprognostic (4.48e-2)" "unprognostic (8.63e-2)" "unprognostic (3.91e-2)" STK11 "LKB1, PJS" ENSG00000118046 "Serine/threonine kinase 11" Q15831 19 1177558-1228431 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Autophagy, Cell cycle, Differentiation, DNA damage, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 142.1;Epicardial cells: 350.2;Late primary spermatocytes: 229.5;Late spermatids: 621.6" "Group enriched" "Detected in all" 9 "Barrier epithelial cells: 350.2;Spermatogenic cell types: 621.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.9" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 1204505.6" "Group enriched" "Detected in many" "cerebral cortex: 225782.1;intestine: 724334.3;lymphoid tissue: 210846.2" "CAB016231, HPA017254, CAB022105, HPA067481" Approved Supported "Nucleoplasm,Primary cilium,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 75 Nucleoplasm "Primary cilium, Centrosome, Cytosol" "CAB016231: , CAB022105: , HPA017254: , HPA067481: " "unprognostic (7.99e-2)" "unprognostic (2.13e-1)" "unprognostic (4.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" "unprognostic (1.31e-1)" "unprognostic (1.27e-1)" "unprognostic (1.03e-3)" "unprognostic (2.56e-1)" "unprognostic (1.45e-3)" "unprognostic (1.35e-1)" "unprognostic (6.62e-2)" "unprognostic (2.48e-3)" "unprognostic (5.75e-3)" "unprognostic (1.26e-1)" "unprognostic (1.59e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (2.62e-2)" "unprognostic (1.19e-1)" "unprognostic (2.01e-2)" "unprognostic (3.81e-2)" "unprognostic (1.41e-2)" "unprognostic (1.02e-2)" "unprognostic (2.53e-3)" "unprognostic (9.25e-2)" "unprognostic (9.37e-3)" "unprognostic (1.65e-1)" "unprognostic (2.81e-1)" "unprognostic (1.30e-3)" STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 82.0;Late primary spermatocytes: 85.3;Late spermatids: 94.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 512818.8" "Tissue enriched" "Detected in some" "cerebral cortex: 1784565.4" HPA029450 Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 70: Non-specific - Protein processing" "Cluster 39: Astrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 102 Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane, Primary cilium, Primary cilium tip, Basal body" "HPA029450: " "unprognostic (1.67e-1)" "unprognostic (1.02e-1)" "unprognostic (3.15e-1)" "unprognostic (2.81e-1)" "unprognostic (2.54e-2)" "unprognostic (2.02e-2)" "unprognostic (5.07e-2)" "unprognostic (1.39e-1)" "unprognostic (7.31e-2)" "unprognostic (6.99e-2)" "potential prognostic favorable (1.48e-4)" "unprognostic (3.04e-3)" "unprognostic (5.82e-2)" "unprognostic (3.70e-3)" "unprognostic (8.15e-3)" "unprognostic (9.75e-2)" "unprognostic (6.74e-2)" "unprognostic (3.08e-1)" "unprognostic (4.74e-2)" "unprognostic (5.55e-2)" "unprognostic (1.50e-1)" "unprognostic (2.90e-1)" "unprognostic (4.01e-1)" "unprognostic (3.62e-1)" "unprognostic (3.72e-1)" "unprognostic (5.38e-2)" "unprognostic (3.23e-1)" "unprognostic (1.74e-1)" "unprognostic (1.19e-1)" "unprognostic (3.51e-1)" "unprognostic (1.15e-1)" STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 389.8;B-cells: 458.1;Neutrophils: 530.7;NK-cells: 459.5;Pancreatic duct cells: 385.0;T-cells: 479.3" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Bergmann glia: 365.7;central nervous system macrophage: 179.4;leukocyte: 423.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 648767.1" "Tissue enriched" "Detected in single" 4223 "lymphoid tissue: 422286.3" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 67: Non-specific - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 1 "Nuclear speckles" "Plasma membrane" "HPA018138: , HPA037979: " "unprognostic (1.30e-1)" "unprognostic (5.74e-2)" "unprognostic (3.62e-1)" "unprognostic (2.34e-3)" "unprognostic (9.70e-3)" "unprognostic (1.23e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-2)" "unprognostic (4.54e-2)" "unprognostic (7.11e-3)" "unprognostic (6.55e-2)" "unprognostic (2.72e-2)" "unprognostic (3.43e-1)" "unprognostic (3.30e-3)" "unprognostic (4.14e-1)" "unprognostic (5.62e-3)" "unprognostic (1.56e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-1)" "unprognostic (2.09e-1)" "unprognostic (7.83e-2)" "unprognostic (4.22e-2)" "unprognostic (3.31e-2)" "unprognostic (8.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.85e-3)" "unprognostic (1.37e-1)" "unprognostic (2.88e-2)" "unprognostic (8.47e-3)" "unprognostic (9.46e-3)" "unprognostic (1.83e-1)" STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133583-196176503 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 355.5;lymphoid tissue: 105.8" "Cell type enhanced" "Detected in many" "B-cells: 616.6;cDC: 761.5;Hematopoietic stem cells: 525.0;Innate lymphoid cells: 639.1;Mast cells: 789.8;Monocyte progenitors: 581.2;monocytes: 783.8;Neutrophil progenitors: 1111.7;Neutrophils: 3217.0;NK-cells: 616.6;T-cells: 869.4;Thymocytes: 653.8" "Cell type enhanced" "Detected in all" "Neutrophils: 3217.0" "Cell type enriched" "Detected in many" 6 "leukocyte: 552.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "lymphoma: 74.3" "Testis - Early spermatids, Testis - Spermatocytes" "Region enriched" "Detected in all" 5 "cerebellum: 63.4" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 1519481.4;T-cells: 2496013.5" "Tissue enriched" "Detected in some" "lymphoid tissue: 3094569.3" "HPA034858, HPA073120" Enhanced Supported Nucleoplasm NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 2 Nucleoplasm "HPA034858: , HPA073120: " "unprognostic (4.00e-2)" "unprognostic (2.13e-1)" "unprognostic (1.95e-1)" "unprognostic (4.30e-1)" "unprognostic (2.76e-1)" "unprognostic (1.71e-1)" "unprognostic (2.91e-1)" "unprognostic (2.16e-1)" "unprognostic (2.51e-3)" "unprognostic (2.07e-1)" "unprognostic (2.73e-2)" "unprognostic (1.42e-1)" "potential prognostic unfavorable (8.88e-5)" "unprognostic (2.44e-1)" "unprognostic (3.00e-1)" "unprognostic (2.23e-3)" "unprognostic (1.04e-2)" "unprognostic (6.65e-2)" "unprognostic (7.30e-2)" "unprognostic (2.04e-2)" "unprognostic (1.81e-1)" "unprognostic (7.49e-2)" "unprognostic (6.89e-3)" "unprognostic (4.06e-1)" "unprognostic (4.18e-2)" "unprognostic (6.79e-3)" "unprognostic (1.41e-2)" "unprognostic (2.98e-1)" "unprognostic (4.56e-2)" "unprognostic (5.11e-2)" "unprognostic (6.04e-2)" STK24 "MST-3, MST3, MST3B, STE20, STK3" ENSG00000102572 "Serine/threonine kinase 24" Q9Y6E0 13 98445185-98577940 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1281.0;Urothelial cells: 643.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1281.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA026435, HPA026502" Enhanced Supported Nucleoli,Cytosol No No 610000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 57 "Nucleoli, Cytosol" "HPA026435: , HPA026502: " "unprognostic (1.00e-2)" "unprognostic (1.16e-1)" "unprognostic (3.45e-2)" "unprognostic (1.85e-2)" "unprognostic (1.40e-2)" "unprognostic (3.65e-2)" "unprognostic (4.64e-2)" "unprognostic (3.51e-1)" "unprognostic (6.86e-3)" "unprognostic (4.62e-3)" "validated prognostic favorable (2.66e-5)" "validated prognostic favorable (8.99e-8)" "unprognostic (6.96e-2)" "unprognostic (2.62e-3)" "potential prognostic unfavorable (7.75e-4)" "validated prognostic unfavorable (1.48e-5)" "validated prognostic unfavorable (3.20e-5)" "unprognostic (1.14e-2)" "unprognostic (2.52e-1)" "unprognostic (2.80e-1)" "unprognostic (4.75e-2)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (6.05e-2)" "unprognostic (9.30e-2)" "unprognostic (4.36e-2)" "unprognostic (4.93e-2)" "unprognostic (1.44e-1)" "unprognostic (7.45e-2)" "unprognostic (2.89e-1)" "unprognostic (5.53e-2)" "unprognostic (1.16e-1)" STK26 "MASK, MST4" ENSG00000134602 "Serine/threonine kinase 26" Q9P289 X 132023302-132075943 "Enzymes, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 66.1;epididymis: 53.1" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 85.4;Monocyte progenitors: 101.8;Neutrophil progenitors: 191.6;Neutrophils: 185.9;Ocular epithelial cells: 83.1;Thymocytes: 101.6" "Cell type enhanced" "Detected in many" "Neutrophils: 191.6" "Cell type enhanced" "Detected in many" "leukocyte: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Breast - Breast myoepithelial cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 2917775.7;T-cells: 4528756.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 17538517.8" HPA059921 Approved Uncertain "Nucleoplasm,Golgi apparatus,Centrosome,Cytosol" Yes No 270000 "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 81 Nucleoplasm "Golgi apparatus, Centrosome, Cytosol" "HPA059921: " "unprognostic (2.45e-1)" "unprognostic (4.29e-2)" "unprognostic (4.73e-2)" "unprognostic (9.41e-2)" "unprognostic (1.55e-1)" "unprognostic (9.40e-2)" "unprognostic (1.31e-1)" "unprognostic (3.46e-2)" "unprognostic (8.20e-3)" "unprognostic (1.52e-2)" "unprognostic (2.73e-2)" "potential prognostic unfavorable (8.03e-5)" "unprognostic (2.21e-3)" "unprognostic (7.80e-3)" "unprognostic (3.30e-1)" "unprognostic (8.23e-2)" "unprognostic (2.50e-1)" "unprognostic (4.34e-1)" "unprognostic (1.47e-1)" "unprognostic (1.46e-3)" "unprognostic (2.45e-1)" "unprognostic (4.51e-1)" "unprognostic (1.42e-1)" "unprognostic (6.43e-2)" "unprognostic (5.88e-2)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (2.89e-1)" "unprognostic (9.39e-2)" STK3 "KRS1, MST2" ENSG00000104375 "Serine/threonine kinase 3" Q13188 8 98371228-98942827 "Enzymes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 4 "dendritic cells: 7.8;granulocytes: 8.8;monocytes: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA007120, CAB025316, HPA073281" Approved Approved "Intermediate filaments,Rods & Rings" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 75: Ovary - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 40: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 87 "Intermediate filaments, Rods & Rings" "CAB025316: , HPA007120: , HPA073281: " "unprognostic (6.12e-2)" "potential prognostic unfavorable (6.91e-4)" "unprognostic (2.78e-1)" "unprognostic (4.50e-2)" "unprognostic (2.74e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (1.86e-1)" "unprognostic (1.70e-1)" "unprognostic (5.79e-3)" "unprognostic (3.73e-2)" "unprognostic (7.91e-3)" "unprognostic (1.54e-2)" "unprognostic (5.39e-2)" "unprognostic (1.24e-2)" "unprognostic (6.31e-2)" "unprognostic (2.89e-3)" "unprognostic (1.28e-1)" "unprognostic (5.86e-2)" "unprognostic (1.03e-1)" "unprognostic (6.06e-3)" "potential prognostic unfavorable (9.19e-4)" "potential prognostic unfavorable (2.19e-4)" "unprognostic (4.43e-3)" "unprognostic (3.82e-1)" "unprognostic (6.20e-2)" "unprognostic (1.07e-1)" "unprognostic (4.75e-2)" "unprognostic (8.04e-2)" "unprognostic (2.22e-1)" "unprognostic (8.93e-2)" "unprognostic (5.00e-2)" STK32B "HSA250839, STK32, STKG6, YANK2" ENSG00000152953 "Serine/threonine kinase 32B" Q9NY57 4 5051480-5500994 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.0;lymphoid tissue: 18.1" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 271.6;Early spermatids: 244.2;Epicardial cells: 129.6;Fibro-adipogenic progenitors: 203.7;Hematopoietic stem cells: 105.8;Loop of henle epithelial cells: 298.7;Lymphatic endothelial cells: 271.8;Microglia: 131.3;Mucous neck cells: 120.5;Oligodendrocyte progenitor cells: 293.8;Oocytes: 142.8;Pancreatic islet cells: 127.7;Proximal tubule cells: 177.1;Thymocytes: 192.3" "Cell type enhanced" "Detected in many" "Endothelial cells: 271.8;Fibro-adipogenic progenitors: 203.7;Glial cells: 293.8;Renal nephron cells: 298.7;Spermatogenic cell types: 244.2" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 199.2;committed oligodendrocyte precursor: 170.8;oligodendrocyte precursor cell: 421.9" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 18.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 31.6;skin cancer: 22.2" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Lung - Fibroblasts_2, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 254 "Distal tubules: 25354.3" "Not detected" "Not detected" HPA015820 Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 69: Skin cancer - ECM organization" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" "Nucleoplasm, Nuclear bodies" Cytosol "HPA015820: " "unprognostic (5.39e-2)" "unprognostic (1.71e-1)" "unprognostic (2.07e-2)" "unprognostic (1.89e-3)" "unprognostic (4.43e-3)" "unprognostic (1.66e-2)" "unprognostic (3.76e-3)" "validated prognostic favorable (2.37e-12)" "validated prognostic favorable (1.53e-4)" "potential prognostic favorable (7.59e-6)" "unprognostic (2.42e-2)" "unprognostic (5.27e-3)" "unprognostic (5.46e-2)" "unprognostic (1.44e-1)" "unprognostic (9.37e-2)" "unprognostic (1.54e-1)" "unprognostic (3.37e-1)" "unprognostic (2.44e-2)" "unprognostic (1.28e-1)" "unprognostic (8.10e-2)" "unprognostic (3.74e-3)" "unprognostic (2.61e-1)" "unprognostic (5.63e-2)" STK36 "FU, KIAA1278" ENSG00000163482 "Serine/threonine kinase 36" Q9NRP7 2 218672069-218702716 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 36.2;Ependymal cells: 43.9;Respiratory ciliated cells: 49.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 49.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 1069178.4" "Tissue enriched" "Detected in single" 693 "fallopian tube: 69259.0" "HPA027409, HPA027453, HPA030058" Approved Supported Cytosol NA NA "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 15 Cytosol "HPA027409: , HPA027453: , HPA030058: " "unprognostic (8.78e-2)" "unprognostic (7.10e-2)" "unprognostic (6.66e-3)" "unprognostic (1.36e-1)" "unprognostic (1.83e-1)" "unprognostic (4.05e-2)" "unprognostic (2.29e-1)" "unprognostic (2.27e-1)" "unprognostic (1.19e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-2)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (4.68e-3)" "unprognostic (2.62e-1)" "unprognostic (8.71e-2)" "unprognostic (1.38e-1)" "unprognostic (1.55e-1)" "unprognostic (2.63e-1)" "unprognostic (1.09e-1)" "unprognostic (5.30e-3)" "unprognostic (1.55e-1)" "unprognostic (7.69e-3)" "unprognostic (1.70e-1)" "unprognostic (1.54e-2)" "unprognostic (1.22e-2)" "unprognostic (2.67e-1)" "unprognostic (5.00e-2)" "unprognostic (1.52e-1)" "unprognostic (7.82e-3)" "unprognostic (1.75e-1)" STK38 "NDR, NDR1" ENSG00000112079 "Serine/threonine kinase 38" Q15208 6 36493892-36547479 "Enzymes, Predicted intracellular proteins" "DNA damage" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 496.7;Neutrophils: 601.2" "Cell type enhanced" "Detected in many" "Neutrophils: 601.2" "Cell type enhanced" "Detected in all" "leukocyte: 384.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 11685153.1" "Low tissue specificity" "Detected in many" "CAB004673, HPA038623, HPA051324" Uncertain Supported Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Spleen - Immune response" "Cluster 25: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 43 Cytosol "CAB004673: , HPA038623: , HPA051324: " "unprognostic (1.67e-1)" "unprognostic (5.30e-3)" "unprognostic (3.65e-1)" "unprognostic (1.16e-1)" "unprognostic (1.10e-1)" "unprognostic (1.08e-1)" "unprognostic (3.60e-1)" "unprognostic (3.62e-2)" "unprognostic (4.00e-2)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (5.76e-3)" "unprognostic (5.24e-2)" "unprognostic (8.54e-2)" "unprognostic (2.11e-3)" "unprognostic (1.88e-1)" "unprognostic (2.70e-2)" "unprognostic (6.39e-2)" "unprognostic (1.50e-2)" "unprognostic (2.19e-1)" "unprognostic (1.95e-1)" "unprognostic (5.94e-2)" "unprognostic (3.79e-2)" "unprognostic (1.17e-1)" "unprognostic (8.09e-3)" "potential prognostic favorable (3.60e-5)" "unprognostic (1.82e-1)" "potential prognostic unfavorable (7.81e-4)" "unprognostic (2.40e-1)" "unprognostic (2.32e-1)" "unprognostic (1.21e-1)" "unprognostic (2.29e-2)" STK38L "KIAA0965, NDR2" ENSG00000211455 "Serine/threonine kinase 38 like" Q9Y2H1 12 27243968-27325959 "Enzymes, Predicted intracellular proteins" "Actin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 80.0" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 396.5;Neutrophil progenitors: 308.5;Neutrophils: 655.3" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 396.5;Neutrophils: 655.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 49.9;granulocytes: 81.2;monocytes: 33.1" "Low cancer specificity" "Detected in all" "Lung - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Smooth muscle cells: 45162546.1" "Low tissue specificity" "Detected in many" "HPA038623, HPA051324" Approved Supported Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 55: Lymphoma - Immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 22 Cytosol "HPA038623: , HPA051324: " "unprognostic (1.93e-1)" "unprognostic (7.73e-2)" "unprognostic (3.33e-1)" "unprognostic (2.38e-2)" "unprognostic (4.27e-1)" "unprognostic (9.02e-2)" "unprognostic (6.21e-2)" "unprognostic (7.94e-3)" "unprognostic (1.27e-1)" "unprognostic (1.61e-1)" "potential prognostic favorable (4.85e-4)" "unprognostic (6.30e-3)" "unprognostic (3.02e-1)" "unprognostic (8.67e-3)" "unprognostic (3.90e-2)" "unprognostic (1.16e-2)" "unprognostic (3.96e-3)" "unprognostic (1.34e-1)" "unprognostic (1.56e-1)" "unprognostic (4.18e-2)" "unprognostic (2.56e-1)" "unprognostic (2.26e-3)" "unprognostic (1.69e-1)" "unprognostic (6.68e-2)" "unprognostic (1.67e-2)" "unprognostic (3.01e-1)" "unprognostic (2.53e-2)" "unprognostic (8.49e-2)" "unprognostic (2.73e-1)" "unprognostic (2.87e-2)" "unprognostic (2.14e-1)" STK4 "KRS2, MST1, YSK3" ENSG00000101109 "Serine/threonine kinase 4" Q13043 20 44966494-45080021 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 46.4;lymphoid tissue: 36.6" "Cell type enhanced" "Detected in all" "B-cells: 579.1;cDC: 653.6;Mast cells: 467.2;Neutrophil progenitors: 625.0;Neutrophils: 1741.0;NK-cells: 610.9;Plasma cells: 411.8;Platelets: 437.0;T-cells: 762.3" "Cell type enhanced" "Detected in all" "Neutrophils: 1741.0;T-cells: 762.3" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 321.7;leukocyte: 640.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 26622271.8;Macrophages: 19990531.6;Neutrophils: 14425216.0;T-cells: 41265735.1" "Tissue enhanced" "Detected in many" "lymphoid tissue: 82138795.9" "CAB004038, HPA015270" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 25000 "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 55: Lymphoma - Immune response" "Cluster 82: Dendritic cells - Antigen presentation" 1018 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB004038: , HPA015270: " "unprognostic (2.08e-3)" "unprognostic (1.25e-1)" "unprognostic (7.24e-2)" "unprognostic (6.45e-2)" "unprognostic (5.37e-2)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (2.25e-2)" "unprognostic (1.23e-1)" "potential prognostic unfavorable (3.27e-4)" "unprognostic (4.02e-2)" "unprognostic (6.35e-2)" "unprognostic (1.73e-2)" "potential prognostic unfavorable (1.51e-5)" "unprognostic (7.54e-2)" "unprognostic (9.17e-2)" "unprognostic (2.47e-1)" "unprognostic (5.90e-3)" "unprognostic (2.38e-1)" "unprognostic (6.33e-2)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (2.49e-1)" "potential prognostic unfavorable (8.24e-5)" "unprognostic (1.58e-2)" "unprognostic (2.37e-2)" "unprognostic (2.18e-3)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" "unprognostic (1.83e-1)" "unprognostic (3.04e-2)" "unprognostic (1.20e-1)" STMN1 "C1orf215, FLJ32206, Lag, LAP18, OP18, PP17, PP19, PR22, SMN" ENSG00000117632 "Stathmin 1" P16949 1 25884181-25906991 "Cancer-related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 1366.8;lymphoid tissue: 1250.2" "Cell type enhanced" "Detected in all" "Early primary spermatocytes: 676.5;Early spermatids: 1053.3;Extravillous trophoblasts: 691.8;Granulosa cells: 978.1;Hofbauer cells: 864.3;Late primary spermatocytes: 943.7;Late spermatids: 3456.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 3456.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 425.4" "Group enriched" "Detected in all" 5 "dendritic cells: 425.4;T-cells: 143.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Kidney - Fibroblasts, Minor Salivary Gland - Mitotic cells (Minor salivary gland), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 240230322.6;Granulosa cells: 179799907.2;Microglia and Neuropil: 335755202.6;Neurons: 211312662.7" "Tissue enhanced" "Detected in all" "cerebral cortex: 1195011662.2" "CAB010107, HPA068438" Enhanced Approved Cytosol NA NA 990000 "Cluster 13: Non-specific - Mitochondria" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 53: Neurons - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 27: Non-specific - Cell proliferation" 20 Cytosol "CAB010107: , HPA068438: " "unprognostic (1.21e-1)" "unprognostic (1.26e-1)" "unprognostic (1.92e-2)" "unprognostic (2.79e-2)" "unprognostic (8.81e-2)" "unprognostic (1.83e-1)" "unprognostic (7.86e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (3.13e-2)" "potential prognostic unfavorable (3.53e-5)" "unprognostic (7.93e-3)" "unprognostic (6.47e-2)" "unprognostic (2.22e-1)" "validated prognostic unfavorable (7.94e-7)" "validated prognostic unfavorable (5.14e-6)" "unprognostic (6.81e-2)" "unprognostic (2.99e-2)" "unprognostic (2.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.94e-2)" "unprognostic (4.68e-1)" "unprognostic (9.91e-2)" "unprognostic (6.85e-3)" "unprognostic (1.26e-2)" "unprognostic (4.55e-2)" "unprognostic (1.77e-2)" "unprognostic (2.11e-2)" "unprognostic (2.80e-1)" "unprognostic (8.70e-2)" "unprognostic (2.31e-1)" "unprognostic (2.50e-2)" STOX1 "C10orf24, FLJ25162" ENSG00000165730 "Storkhead box 1" Q6ZVD7 10 68827531-68895432 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.7;choroid plexus: 26.1" "Cell type enhanced" "Detected in many" "Astrocytes: 155.1;Choroid plexus epithelial cells: 307.6;Endometrial ciliated cells: 115.3;Ependymal cells: 93.1;Epididymal efferent duct ciliated cells: 114.2;Fallopian tube ciliated cells: 137.6;Medullary thymic epithelial cells: 81.6;Pituitary stem cells: 155.0;Respiratory ciliated cells: 186.7;Retinal pigment epithelial cells: 68.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 307.6;Glial cells: 155.1;Stem cells: 155.0" "Group enriched" "Detected in all" 5 "astrocyte: 132.4;choroid plexus epithelial cell: 300.5;ependymal cell: 102.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.0" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Lung - Respiratory ciliated cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 117 "Fallopian tube cells: 11681.0" "Not detected" "Not detected" "HPA037844, HPA037845" Uncertain Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No NA "Cluster 24: Non-specific - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 52: Non-specific - Mitochondria" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 3 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA037844: , HPA037845: " "unprognostic (1.94e-2)" "potential prognostic favorable (4.37e-4)" "unprognostic (2.53e-1)" "unprognostic (6.72e-2)" "unprognostic (2.29e-1)" "unprognostic (5.39e-3)" "unprognostic (4.82e-3)" "unprognostic (1.04e-2)" "unprognostic (4.80e-2)" "unprognostic (1.61e-1)" "unprognostic (5.68e-2)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (1.15e-2)" "unprognostic (2.69e-1)" "unprognostic (1.20e-3)" "potential prognostic favorable (6.43e-6)" "unprognostic (2.00e-2)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (6.58e-3)" "unprognostic (1.69e-1)" "unprognostic (7.25e-2)" "unprognostic (2.00e-1)" "unprognostic (5.77e-2)" "unprognostic (1.72e-1)" STRADA "LYK5, NY-BR-96, Stlk, STRAD" ENSG00000266173 "STE20 related adaptor alpha" Q7RTN6 17 63682336-63741986 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 76.0;Bergmann glia: 82.0;Brain excitatory neurons: 59.6;Brain inhibitory neurons: 55.8;Cardiomyocytes: 74.7;Choroid plexus epithelial cells: 73.1;Ependymal cells: 79.2;Epicardial cells: 84.1;Microglia: 86.7;Oligodendrocyte progenitor cells: 51.8;Oligodendrocytes: 97.2;Other brain neurons: 50.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 84.1;Ciliated cells: 79.2;Glial cells: 97.2;Myocytes: 74.7;Neuronal cells: 59.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 1601024.1" "Group enriched" "Detected in some" "cerebral cortex: 1296338.0;fallopian tube: 2189900.1;kidney: 700275.6;lymphoid tissue: 2319969.8" HPA031637 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 64: Non-specific - Transcription" "Cluster 1: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Nucleoplasm, Cytosol" "HPA031637: " "unprognostic (4.08e-2)" "unprognostic (7.43e-2)" "unprognostic (7.77e-2)" "unprognostic (1.57e-1)" "unprognostic (7.30e-3)" "unprognostic (2.09e-2)" "unprognostic (2.26e-1)" "unprognostic (3.38e-2)" "unprognostic (1.06e-1)" "unprognostic (7.72e-3)" "potential prognostic unfavorable (3.03e-5)" "unprognostic (1.51e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (4.26e-4)" "unprognostic (8.61e-2)" "unprognostic (3.03e-1)" "unprognostic (3.06e-2)" "unprognostic (3.33e-1)" "unprognostic (1.86e-2)" "unprognostic (3.10e-1)" "unprognostic (3.04e-3)" "unprognostic (1.20e-3)" "unprognostic (1.18e-3)" "unprognostic (1.47e-2)" "unprognostic (4.23e-3)" "unprognostic (7.11e-2)" "unprognostic (1.75e-2)" "unprognostic (2.06e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-1)" "unprognostic (4.14e-1)" STRADB "ALS2CR2, CALS-21, ILPIP, ILPIPA, PAPK" ENSG00000082146 "STE20 related adaptor beta" Q9C0K7 2 201387858-201480846 "Enzymes, Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 8 "Cardiomyocytes: 1662.8" "Cell type enriched" "Detected in many" 8 "Myocytes: 1662.8" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 204.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 64857.9;Oocytes: 142372.2;Skeletal myofibers: 63063.3" "Tissue enriched" "Detected in single" 703 "bone marrow: 70348.3" "HPA026549, HPA028520" Approved Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 13 "Nucleoplasm, Cytosol" "Primary cilium, Primary cilium tip" "HPA026549: , HPA028520: " "unprognostic (9.75e-2)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.45e-2)" "unprognostic (9.70e-2)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.01e-2)" "unprognostic (3.02e-2)" "unprognostic (4.31e-1)" "unprognostic (1.23e-1)" "unprognostic (1.49e-2)" "unprognostic (4.55e-2)" "unprognostic (3.97e-2)" "unprognostic (1.78e-1)" "unprognostic (2.15e-1)" "unprognostic (8.55e-2)" "unprognostic (6.28e-3)" "unprognostic (1.39e-1)" "unprognostic (1.41e-1)" "unprognostic (6.99e-3)" "unprognostic (1.42e-1)" "unprognostic (7.86e-2)" "potential prognostic unfavorable (4.31e-4)" "potential prognostic unfavorable (8.07e-4)" "unprognostic (2.29e-1)" "unprognostic (2.23e-1)" "potential prognostic favorable (4.37e-4)" "unprognostic (2.08e-1)" STRN "PPP2R6A, STRN1" ENSG00000115808 Striatin O43815 2 36837698-36966536 "Cancer-related genes, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 434.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" HPA017286 Approved Approved Nucleoplasm,Cytosol No No "Cluster 11: Esophagus - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 85 Cytosol Nucleoplasm "HPA017286: " "unprognostic (4.67e-1)" "unprognostic (6.72e-2)" "unprognostic (2.37e-1)" "unprognostic (1.20e-2)" "unprognostic (5.81e-2)" "unprognostic (1.57e-1)" "unprognostic (4.71e-2)" "unprognostic (2.61e-1)" "unprognostic (1.25e-1)" "unprognostic (4.11e-2)" "potential prognostic favorable (7.55e-7)" "unprognostic (1.59e-2)" "unprognostic (1.43e-2)" "unprognostic (9.18e-3)" "unprognostic (7.03e-3)" "unprognostic (2.68e-2)" "unprognostic (5.52e-3)" "unprognostic (2.19e-1)" "unprognostic (2.56e-1)" "unprognostic (1.44e-2)" "unprognostic (5.66e-2)" "potential prognostic unfavorable (2.50e-4)" "unprognostic (7.75e-3)" "unprognostic (2.12e-1)" "unprognostic (2.96e-3)" "unprognostic (1.82e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "unprognostic (1.31e-1)" "unprognostic (4.78e-2)" "unprognostic (3.04e-2)" STRN3 "PPP2R6B, S/G2NA, SG2NA" ENSG00000196792 "Striatin 3" Q13033 14 30893799-31026401 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA003392, HPA004636, CAB069925" Approved Approved "Plasma membrane,Actin filaments,Primary cilium,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 103: Non-specific - Basic cellular processes" 83 "Plasma membrane, Cytosol" "Actin filaments, Primary cilium" "CAB069925: , HPA003392: , HPA004636: " "unprognostic (1.55e-1)" "unprognostic (9.38e-2)" "unprognostic (1.24e-1)" "unprognostic (9.62e-2)" "unprognostic (2.18e-2)" "unprognostic (4.60e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-3)" "unprognostic (3.84e-2)" "unprognostic (1.30e-2)" "potential prognostic favorable (8.06e-6)" "unprognostic (4.03e-3)" "unprognostic (8.28e-2)" "unprognostic (6.37e-2)" "unprognostic (7.86e-2)" "unprognostic (1.04e-2)" "unprognostic (6.28e-3)" "unprognostic (1.17e-1)" "unprognostic (3.75e-1)" "unprognostic (2.85e-2)" "unprognostic (1.42e-3)" "unprognostic (3.02e-2)" "unprognostic (3.44e-2)" "unprognostic (1.32e-1)" "unprognostic (3.47e-1)" "unprognostic (2.20e-1)" "unprognostic (2.67e-1)" "unprognostic (1.39e-2)" "unprognostic (8.07e-2)" "unprognostic (4.49e-2)" "unprognostic (4.42e-2)" STT3B "FLJ90106, SIMP, STT3-B" ENSG00000163527 "STT3 oligosaccharyltransferase complex catalytic subunit B" Q8TCJ2 3 31532638-31637616 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Congenital disorder of glycosylation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 429.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 84452880.3" "Low tissue specificity" "Detected in many" "HPA036448, HPA036646" Approved Supported "Endoplasmic reticulum" NA NA 7100 "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 105 "Endoplasmic reticulum" "HPA036448: , HPA036646: " "unprognostic (2.69e-1)" "unprognostic (5.15e-2)" "unprognostic (1.79e-2)" "unprognostic (4.48e-3)" "unprognostic (5.02e-2)" "unprognostic (1.24e-1)" "unprognostic (2.50e-1)" "unprognostic (1.08e-2)" "unprognostic (9.25e-3)" "unprognostic (1.27e-2)" "potential prognostic favorable (5.45e-5)" "unprognostic (1.22e-1)" "unprognostic (7.06e-2)" "unprognostic (3.08e-2)" "unprognostic (1.10e-1)" "unprognostic (2.86e-2)" "unprognostic (1.36e-1)" "unprognostic (5.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.35e-1)" "unprognostic (4.31e-3)" "unprognostic (3.46e-3)" "unprognostic (3.33e-1)" "unprognostic (1.32e-1)" "unprognostic (1.79e-3)" "unprognostic (5.98e-2)" "unprognostic (2.96e-3)" "unprognostic (1.64e-1)" "unprognostic (1.85e-1)" "unprognostic (5.00e-2)" "unprognostic (1.17e-1)" STX12 "STX13, STX14" ENSG00000117758 "Syntaxin 12" Q86Y82 1 27773219-27824443 "Predicted intracellular proteins, Predicted membrane proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 438.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "cerebral cortex: 369096598.1" "HPA041038, HPA055300" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles" No No 27000 "Cluster 40: Monocytes - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 27: Non-specific - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 147 "Nucleoplasm, Golgi apparatus, Vesicles" "HPA041038: , HPA055300: " "unprognostic (7.08e-3)" "unprognostic (1.21e-1)" "unprognostic (7.68e-2)" "unprognostic (4.70e-2)" "unprognostic (3.62e-1)" "unprognostic (1.25e-1)" "unprognostic (1.75e-1)" "unprognostic (7.27e-2)" "unprognostic (2.57e-2)" "potential prognostic unfavorable (4.26e-4)" "potential prognostic favorable (1.34e-8)" "unprognostic (3.83e-3)" "unprognostic (1.37e-1)" "unprognostic (1.18e-3)" "unprognostic (2.27e-2)" "unprognostic (2.95e-1)" "unprognostic (1.35e-1)" "unprognostic (2.89e-2)" "unprognostic (1.31e-2)" "unprognostic (3.47e-2)" "unprognostic (2.76e-2)" "unprognostic (2.46e-1)" "unprognostic (2.44e-2)" "unprognostic (1.02e-1)" "unprognostic (2.04e-1)" "unprognostic (7.39e-2)" "unprognostic (9.38e-2)" "unprognostic (2.62e-2)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.79e-1)" STXBP1 "hUNC18, MUNC18-1, nSec1, rbSec1, UNC18" ENSG00000136854 "Syntaxin binding protein 1" P61764 9 127579370-127696027 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Disease variant, Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 252.0;retina: 188.2" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 304.0;Cone photoreceptor cells: 285.7;Corticotrophs: 227.6;Gonadotrophs: 315.4;Lactotrophs: 382.5;Retinal amacrine cells: 250.4;Rod photoreceptor cells: 457.6;Somatotrophs: 464.6;Thyrotrophs: 295.3" "Cell type enhanced" "Detected in many" "Neuronal cells: 457.6;Pituitary endocrine cells: 464.6" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Skin Cutaneous Melanoma (TCGA): 105.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 120.7" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 1394536009.6;Microglia and Neuropil: 1809596863.7;Neurons: 521489924.3" "Tissue enriched" "Detected in many" "cerebral cortex: 1763774913.4" "HPA008209, HPA023483, CAB034434" Enhanced Uncertain "Nucleoplasm,Nucleoli,Basal body,Cytosol" NA NA 63000 "Cluster 31: T-cells - T-cell receptor" "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 36 Nucleoplasm "Nucleoli, Basal body, Cytosol" "CAB034434: , HPA008209: , HPA023483: " "unprognostic (4.17e-3)" "unprognostic (1.23e-2)" "unprognostic (2.92e-1)" "unprognostic (1.18e-1)" "unprognostic (4.42e-2)" "potential prognostic unfavorable (6.52e-7)" "unprognostic (1.41e-1)" "unprognostic (5.81e-3)" "potential prognostic unfavorable (2.14e-4)" "unprognostic (1.08e-1)" "validated prognostic favorable (5.80e-6)" "validated prognostic favorable (1.72e-4)" "unprognostic (7.06e-2)" "potential prognostic unfavorable (3.49e-4)" "unprognostic (5.08e-2)" "unprognostic (8.08e-3)" "unprognostic (2.35e-1)" "potential prognostic unfavorable (6.37e-4)" "unprognostic (1.21e-1)" "unprognostic (2.26e-2)" "unprognostic (3.77e-1)" "unprognostic (1.93e-3)" "unprognostic (3.24e-1)" "unprognostic (3.51e-2)" "unprognostic (3.21e-3)" "unprognostic (4.43e-2)" "unprognostic (2.59e-1)" "unprognostic (1.31e-1)" "unprognostic (3.83e-2)" "unprognostic (4.83e-1)" "unprognostic (2.30e-3)" STXBP2 "Hunc18b, MUNC18-2, Unc18-2, UNC18B" ENSG00000076944 "Syntaxin binding protein 2" Q15833 19 7636772-7647873 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Exocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 153.1" "Cell type enhanced" "Detected in many" "Late spermatids: 320.5;Megakaryocytes: 253.4;monocytes: 273.8;Neutrophil progenitors: 300.6;Neutrophils: 901.0;Platelets: 480.7" "Cell type enhanced" "Detected in many" "Neutrophils: 901.0;Platelets: 480.7" "Group enriched" "Detected in some" 5 "central nervous system macrophage: 20.7;choroid plexus epithelial cell: 8.2;leukocyte: 31.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 837.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Breast - Breast glandular cells, Heart muscle - Macrophages, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Skin - Keratinocyte (other), Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Proximal tubules: 31041057.7" "Tissue enhanced" "Detected in many" "bone marrow: 50863390.5" "HPA015564, HPA063868" Approved Enhanced Cytosol No No 900000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 5: Spleen - Immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 Cytosol "HPA015564: , HPA063868: " "unprognostic (9.74e-2)" "unprognostic (2.67e-1)" "unprognostic (2.93e-1)" "unprognostic (1.93e-2)" "unprognostic (1.03e-1)" "unprognostic (4.85e-2)" "unprognostic (5.97e-2)" "unprognostic (3.60e-2)" "unprognostic (4.87e-2)" "unprognostic (1.58e-1)" "unprognostic (7.00e-2)" "unprognostic (6.99e-3)" "unprognostic (7.01e-2)" "unprognostic (3.90e-3)" "unprognostic (2.99e-2)" "unprognostic (3.38e-2)" "unprognostic (6.08e-2)" "unprognostic (2.95e-1)" "unprognostic (1.77e-1)" "unprognostic (6.98e-2)" "unprognostic (1.84e-1)" "unprognostic (2.35e-2)" "unprognostic (1.44e-1)" "unprognostic (8.45e-2)" "unprognostic (1.54e-1)" "unprognostic (1.56e-1)" "unprognostic (2.12e-1)" "unprognostic (5.65e-2)" "unprognostic (9.54e-2)" "unprognostic (5.16e-2)" "unprognostic (5.88e-2)" STXBP4 "MGC50337, Synip" ENSG00000166263 "Syntaxin binding protein 4" Q6ZWJ1 17 54968727-55173632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 197.5;Cone photoreceptor cells: 204.9;Distal convoluted tubule cells: 229.5;Ependymal cells: 313.9;Loop of henle epithelial cells: 201.0;Renal connecting tubule cells: 212.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 313.9" "Cell type enhanced" "Detected in all" "ependymal cell: 343.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 1936996.0;Distal tubules: 2155544.2" "Group enriched" "Detected in some" 100 "fallopian tube: 10226.1;intestine: 9857.3" "CAB007760, HPA022138, HPA022888, HPA024227" Approved Approved "Plasma membrane,Cytosol" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 110: Mural cells - ECM organization" 10 "Plasma membrane" Cytosol "CAB007760: , HPA022138: , HPA022888: , HPA024227: " "unprognostic (2.51e-2)" "unprognostic (3.23e-2)" "unprognostic (5.98e-2)" "unprognostic (1.02e-1)" "unprognostic (1.27e-2)" "unprognostic (1.02e-1)" "unprognostic (3.70e-2)" "unprognostic (2.21e-1)" "unprognostic (3.22e-1)" "unprognostic (3.01e-2)" "potential prognostic favorable (1.33e-4)" "unprognostic (4.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.95e-2)" "unprognostic (1.07e-1)" "unprognostic (6.54e-2)" "unprognostic (1.80e-1)" "unprognostic (1.22e-2)" "unprognostic (1.28e-1)" "unprognostic (1.36e-1)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (5.06e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (3.95e-4)" "unprognostic (2.86e-1)" "unprognostic (1.17e-1)" "unprognostic (1.65e-1)" "unprognostic (3.11e-1)" "unprognostic (1.06e-1)" SUCLA2 LINC00444 ENSG00000136143 "Succinate-CoA ligase ADP-forming subunit beta" Q9P2R7 13 47745736-48037968 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 217.4;tongue: 253.9" "Cell type enhanced" "Detected in all" "Early spermatids: 423.7;Late spermatids: 485.9" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 485.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Minor Salivary Gland - Endothelial cells, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 600930237.3" "Tissue enhanced" "Detected in all" "heart muscle: 144028181.9" "HPA039435, HPA039536, HPA061528" Enhanced Supported Enhanced Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 34: Non-specific - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 23 Mitochondria "HPA039435: , HPA039536: , HPA061528: " "unprognostic (1.55e-1)" "unprognostic (3.11e-2)" "unprognostic (7.58e-3)" "unprognostic (3.01e-3)" "unprognostic (1.42e-1)" "unprognostic (1.68e-1)" "unprognostic (6.25e-2)" "unprognostic (3.42e-1)" "unprognostic (1.10e-2)" "unprognostic (2.01e-2)" "validated prognostic favorable (7.55e-13)" "validated prognostic favorable (6.23e-4)" "potential prognostic favorable (3.05e-4)" "unprognostic (1.33e-1)" "unprognostic (7.60e-3)" "potential prognostic unfavorable (6.29e-4)" "unprognostic (1.20e-2)" "unprognostic (1.33e-1)" "unprognostic (7.21e-2)" "unprognostic (3.21e-2)" "unprognostic (3.49e-3)" "unprognostic (5.00e-2)" "unprognostic (2.29e-1)" "unprognostic (3.34e-1)" "unprognostic (2.22e-2)" "unprognostic (7.94e-2)" "unprognostic (1.18e-2)" "unprognostic (2.62e-1)" "unprognostic (2.88e-1)" "unprognostic (3.64e-1)" "unprognostic (6.88e-2)" SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 516.6" "Cell type enhanced" "Detected in all" "Enteric stem cells: 398.2;Enteric transient amplifying cells: 434.9;Enterocytes: 620.3;Esophageal apical cells: 644.6;Esophageal suprabasal cells: 410.4;Parietal cells: 424.3" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 644.6;Enterocytes: 620.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 217711895.1;Distal tubules: 246038433.2" "Tissue enhanced" "Detected in all" "heart muscle: 269338336.9" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" NA NA 170000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 97: Non-specific - Cellular respiration" 8 Mitochondria "Plasma membrane, Cytosol" "HPA036683: , HPA036684: " "unprognostic (1.91e-2)" "unprognostic (5.94e-3)" "unprognostic (6.16e-2)" "unprognostic (1.06e-2)" "unprognostic (1.16e-1)" "unprognostic (1.64e-2)" "unprognostic (3.44e-2)" "unprognostic (2.50e-2)" "unprognostic (2.36e-1)" "unprognostic (6.68e-2)" "potential prognostic favorable (1.23e-7)" "unprognostic (3.39e-2)" "unprognostic (4.83e-3)" "unprognostic (1.31e-2)" "unprognostic (2.17e-2)" "unprognostic (4.40e-2)" "unprognostic (4.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.29e-1)" "unprognostic (1.52e-1)" "unprognostic (1.53e-1)" "unprognostic (2.38e-1)" "unprognostic (1.64e-1)" "unprognostic (1.21e-1)" "unprognostic (8.58e-2)" "unprognostic (1.21e-2)" "unprognostic (1.65e-1)" "unprognostic (2.16e-1)" "unprognostic (1.69e-1)" "unprognostic (1.53e-1)" "unprognostic (3.96e-2)" SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming subunit beta" Q96I99 3 67360460-67654612 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 259.9" "Cell type enhanced" "Detected in all" "Hepatocytes: 623.4;Parietal cells: 1196.9" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 1196.9" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 358.3;leukocyte: 376.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Stomach - Parietal cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubules: 993507544.4;Proximal tubules: 923553821.7" "Low tissue specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 270000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 76: Non-specific - Metabolism" "Cluster 39: Astrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 97: Non-specific - Cellular respiration" 10 Mitochondria "Plasma membrane" "HPA046705: , HPA051998: " "unprognostic (1.46e-3)" "unprognostic (1.67e-1)" "unprognostic (1.04e-2)" "unprognostic (6.11e-3)" "potential prognostic favorable (2.22e-5)" "unprognostic (2.43e-2)" "unprognostic (9.36e-2)" "potential prognostic unfavorable (8.31e-5)" "unprognostic (8.47e-2)" "unprognostic (6.18e-2)" "potential prognostic favorable (1.22e-7)" "unprognostic (9.03e-3)" "potential prognostic favorable (7.56e-4)" "unprognostic (4.43e-2)" "unprognostic (7.52e-3)" "unprognostic (2.15e-2)" "unprognostic (3.43e-2)" "unprognostic (1.01e-1)" "unprognostic (2.89e-2)" "unprognostic (2.09e-1)" "unprognostic (3.17e-2)" "unprognostic (5.21e-3)" "unprognostic (1.27e-2)" "unprognostic (8.82e-3)" "unprognostic (3.45e-2)" "unprognostic (3.79e-2)" "unprognostic (7.50e-2)" "unprognostic (2.98e-1)" "unprognostic (1.54e-1)" "unprognostic (2.38e-2)" "unprognostic (5.47e-3)" SUFU "PRO1280, SUFUH, SUFUXL" ENSG00000107882 "SUFU negative regulator of hedgehog signaling" Q9UMX1 10 102503972-102633535 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Ciliopathy, Disease variant, Joubert syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 259.2;Late spermatids: 178.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 259.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 543 "Collecting ducts: 35222.6;Glomeruli: 65899.6;Granulosa cells: 58905.7;Macrophages: 57134.9" "Group enriched" "Detected in many" "intestine: 276860.6;skin: 919593.6" HPA008700 Supported Supported "Nucleoplasm,Primary cilium" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 54: Immune cells - T cell receptor" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 72 Nucleoplasm "Primary cilium" "HPA008700: " "unprognostic (2.19e-2)" "unprognostic (4.00e-2)" "unprognostic (4.00e-2)" "unprognostic (4.36e-2)" "unprognostic (3.33e-1)" "unprognostic (1.90e-1)" "unprognostic (3.94e-1)" "unprognostic (1.37e-2)" "unprognostic (1.94e-2)" "unprognostic (1.52e-1)" "potential prognostic favorable (2.78e-5)" "unprognostic (3.07e-2)" "unprognostic (8.83e-2)" "unprognostic (2.78e-2)" "unprognostic (1.49e-1)" "unprognostic (1.69e-1)" "unprognostic (5.19e-2)" "unprognostic (6.94e-2)" "unprognostic (9.36e-2)" "unprognostic (1.15e-2)" "potential prognostic unfavorable (1.49e-4)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (3.63e-1)" "unprognostic (1.34e-1)" "unprognostic (1.18e-1)" "unprognostic (2.93e-1)" "unprognostic (2.49e-1)" "unprognostic (6.16e-2)" "unprognostic (9.71e-2)" "unprognostic (2.93e-1)" SUGCT "C7orf10, DERP13, FLJ11808, ORF19" ENSG00000175600 "Succinyl-CoA:glutarate-CoA transferase" Q9HAC7 7 40135005-40860763 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Glutaricaciduria" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 41.4;liver: 26.6" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 269.7;Choroid plexus epithelial cells: 249.3;Ependymal cells: 246.3;Myonuclei: 260.7;Proximal tubule cells: 910.5" "Cell type enhanced" "Detected in all" "Renal nephron cells: 910.5" "Cell type enhanced" "Detected in all" "ependymal cell: 260.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD4 T-cell: 1.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes, Skeletal muscle - Skeletal myocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Proximal tubules: 26008041.3" "Group enriched" "Detected in some" "kidney: 10301869.2;liver: 8784488.0" "HPA026698, HPA026704, HPA026705" Enhanced Approved "Microtubules,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 76: Non-specific - Metabolism" "Cluster 3: Choroid plexus - Cilium" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 88: Proximal tubular cells - Transmembrane transport" "Microtubules, Primary cilium" "Mitotic spindle, Basal body" "HPA026698: , HPA026704: , HPA026705: " "unprognostic (7.79e-2)" "unprognostic (1.12e-1)" "unprognostic (2.97e-2)" "unprognostic (2.96e-1)" "unprognostic (2.71e-1)" "unprognostic (1.30e-1)" "unprognostic (2.93e-3)" "unprognostic (6.49e-2)" "validated prognostic favorable (5.65e-13)" "validated prognostic favorable (4.29e-4)" "unprognostic (1.74e-2)" "potential prognostic favorable (3.25e-4)" "unprognostic (2.86e-3)" "potential prognostic unfavorable (5.78e-4)" "unprognostic (9.58e-2)" "unprognostic (1.68e-2)" "unprognostic (7.68e-2)" "unprognostic (1.22e-3)" "unprognostic (4.58e-3)" "unprognostic (9.97e-2)" "unprognostic (2.57e-1)" "unprognostic (3.34e-1)" "unprognostic (4.06e-2)" "unprognostic (5.32e-1)" "unprognostic (2.34e-3)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (2.66e-5)" "unprognostic (1.26e-2)" SULT2A1 "DHEA-ST, STD" ENSG00000105398 "Sulfotransferase family 2A member 1" Q06520 19 47870467-47886315 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Bile acid catabolism, Lipid degradation, Lipid metabolism, Steroid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "liver: 1005.4" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 2000.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 2000.0" "Low cell type specificity" "Detected in some" "Cancer enriched" "Detected in some" 36 "Liver Hepatocellular Carcinoma (TCGA): 316.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.4" "Cancer enriched" "Detected in single" 8 "liver cancer: 7.7" "Adrenal gland - Adrenal cortex cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Hepatocytes: 557903544.3" "Tissue enriched" "Detected in many" "liver: 327949791.7" "CAB018755, HPA041487, HPA063633" Enhanced Supported Cytosol NA NA 760000 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 48: Non-specific - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 93: Hepatocytes - Bile production & excretion" 5 Cytosol "CAB018755: , HPA041487: , HPA063633: " "unprognostic (1.88e-2)" "unprognostic (7.27e-2)" "unprognostic (5.62e-2)" "unprognostic (6.47e-3)" "unprognostic (1.69e-3)" "unprognostic (2.91e-1)" "unprognostic (8.92e-2)" "unprognostic (1.68e-1)" "unprognostic (3.45e-2)" "unprognostic (1.65e-2)" SULT2B1 HSST2 ENSG00000088002 "Sulfotransferase family 2B member 1" O00204 19 48552172-48599425 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" Transferase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 105.9;esophagus: 305.3;skin 1: 195.8;vagina: 152.9" "Group enriched" "Detected in many" 4 "Esophageal apical cells: 3869.3;Esophageal suprabasal cells: 1084.6" "Group enriched" "Detected in many" 11 "Apical squamous epithelial cells: 3869.3;Suprabasal cells: 1084.6" "Cell type enhanced" "Detected in many" "leukocyte: 6.7" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 90.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Alveolar cells type 1, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Keratinocytes: 19310167.6" "Tissue enhanced" "Detected in many" "lung: 5334737.3" "HPA041724, HPA043539, HPA076510" Enhanced Enhanced Vesicles,Cytosol NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 85: Squamous epithelial cells - Keratinization" 11 Vesicles Cytosol "HPA041724: , HPA043539: , HPA076510: " "unprognostic (3.19e-1)" "unprognostic (1.56e-2)" "unprognostic (2.13e-1)" "unprognostic (9.55e-2)" "unprognostic (9.46e-3)" "unprognostic (3.99e-2)" "unprognostic (1.03e-1)" "unprognostic (9.06e-2)" "unprognostic (1.91e-1)" "unprognostic (1.48e-2)" "unprognostic (5.64e-2)" "unprognostic (2.28e-2)" "unprognostic (6.49e-3)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (6.87e-2)" "unprognostic (9.68e-2)" "unprognostic (1.44e-1)" "unprognostic (4.68e-3)" "unprognostic (4.38e-2)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (6.87e-4)" "unprognostic (6.28e-2)" "unprognostic (2.45e-1)" "unprognostic (1.32e-1)" "unprognostic (3.06e-1)" "unprognostic (1.79e-3)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (1.99e-2)" SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" "No annotated function" Yes No 370000 "Cluster 13: Non-specific - Mitochondria" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 21: Non-specific - Metabolism" "Cluster 67: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 13 "Vesicles, Plasma membrane" "CAB025743: , HPA024040: , HPA074892: " "unprognostic (2.40e-3)" "unprognostic (1.38e-1)" "unprognostic (9.82e-2)" "unprognostic (1.13e-3)" "unprognostic (3.25e-2)" "unprognostic (3.89e-2)" "unprognostic (9.68e-3)" "unprognostic (7.51e-3)" "unprognostic (9.08e-2)" "unprognostic (1.08e-1)" "potential prognostic favorable (5.63e-6)" "unprognostic (3.65e-1)" "unprognostic (1.71e-1)" "unprognostic (9.37e-3)" "unprognostic (7.48e-3)" "unprognostic (3.35e-2)" "unprognostic (1.77e-1)" "unprognostic (2.16e-1)" "unprognostic (7.57e-2)" "unprognostic (4.89e-1)" "unprognostic (3.34e-1)" "unprognostic (2.75e-1)" "unprognostic (1.38e-1)" "unprognostic (6.30e-2)" "unprognostic (2.61e-1)" "unprognostic (4.87e-2)" "unprognostic (7.59e-2)" "unprognostic (6.18e-3)" "unprognostic (2.64e-1)" "unprognostic (1.06e-2)" "unprognostic (2.43e-2)" SUMO2 "SMT3B, SMT3H2" ENSG00000188612 "Small ubiquitin like modifier 2" P61956 17 75165586-75182959 "Essential proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 202.2;Late primary spermatocytes: 279.4;Late spermatids: 394.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 394.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 429947.2;Keratinocytes: 721623.3" "Low tissue specificity" "Detected in many" "CAB037314, HPA042123, HPA048064" Supported Supported "Nucleoplasm,Nuclear bodies,Calyx,Connecting piece,Flagellar centriole" NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Protein processing" 139 "Nucleoplasm, Nuclear bodies" "Calyx, Connecting piece, Flagellar centriole" "CAB037314: , HPA042123: , HPA048064: " "unprognostic (2.87e-2)" "unprognostic (2.12e-1)" "unprognostic (4.84e-2)" "unprognostic (5.78e-3)" "unprognostic (9.77e-3)" "unprognostic (1.52e-2)" "unprognostic (2.00e-1)" "unprognostic (5.15e-2)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (1.76e-2)" "potential prognostic favorable (7.18e-6)" "unprognostic (5.46e-2)" "unprognostic (1.50e-2)" "unprognostic (3.99e-3)" "potential prognostic unfavorable (4.91e-4)" "validated prognostic unfavorable (8.63e-4)" "validated prognostic unfavorable (7.56e-5)" "unprognostic (8.05e-2)" "unprognostic (3.41e-2)" "unprognostic (4.45e-3)" "unprognostic (6.56e-2)" "unprognostic (3.13e-2)" "unprognostic (1.32e-1)" "unprognostic (1.86e-3)" "unprognostic (3.77e-2)" "unprognostic (4.43e-2)" "unprognostic (1.54e-1)" "unprognostic (5.02e-2)" "unprognostic (3.15e-1)" "unprognostic (1.61e-1)" "unprognostic (2.09e-2)" SUMO3 "SMT3A, SMT3H1" ENSG00000184900 "Small ubiquitin like modifier 3" P55854 21 44805617-44818779 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocytes: 426.5" "Cell type enhanced" "Detected in all" "Megakaryocytes: 426.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Low tissue specificity" "Detected in many" "CAB012180, HPA042123, HPA048064" Supported Supported "Nucleoplasm,Nuclear bodies,Calyx,Connecting piece,Flagellar centriole" NA NA "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 47: Platelets - Hemostasis" 35 "Nucleoplasm, Nuclear bodies" "Calyx, Connecting piece, Flagellar centriole" "CAB012180: , HPA042123: , HPA048064: " "unprognostic (5.52e-2)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "unprognostic (1.58e-1)" "unprognostic (7.67e-3)" "unprognostic (2.32e-1)" "unprognostic (2.69e-1)" "unprognostic (4.09e-2)" "unprognostic (1.72e-1)" "unprognostic (5.49e-2)" "unprognostic (1.07e-3)" "unprognostic (6.40e-2)" "unprognostic (7.18e-2)" "unprognostic (5.20e-2)" "unprognostic (2.80e-2)" "unprognostic (9.03e-3)" "unprognostic (4.37e-2)" "unprognostic (6.09e-2)" "unprognostic (4.76e-1)" "unprognostic (2.01e-2)" "unprognostic (2.87e-2)" "unprognostic (1.46e-2)" "unprognostic (2.11e-1)" "unprognostic (1.14e-1)" "unprognostic (8.27e-2)" "unprognostic (4.96e-2)" "unprognostic (4.46e-2)" "unprognostic (2.92e-3)" "unprognostic (8.19e-2)" "unprognostic (3.84e-2)" "unprognostic (2.19e-1)" SUMO4 "dJ281H8.4, IDDM5, SMT3H4" ENSG00000177688 "Small ubiquitin like modifier 4" Q6EEV6 6 149400262-149401278 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Colon - Enteric glia cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA042123, HPA048064" Uncertain Supported "Nucleoplasm,Nuclear bodies,Calyx,Connecting piece,Flagellar centriole" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 6: Non-specific - Immune response" "Cluster 61: BICR 18 - Protein kinases" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 6 "Nucleoplasm, Nuclear bodies" "Calyx, Connecting piece, Flagellar centriole" "HPA042123: , HPA048064: " "unprognostic (7.38e-2)" "unprognostic (1.78e-2)" "unprognostic (4.20e-2)" "potential prognostic unfavorable (3.03e-4)" "unprognostic (1.52e-2)" SURF2 ENSG00000148291 "Surfeit 2" Q15527 9 133356550-133361158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 102.1" "Cell type enhanced" "Detected in many" "Early spermatids: 418.6;Late primary spermatocytes: 470.6;Late spermatids: 1267.7;Oocytes: 294.7" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 1267.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 3320838.2" "Tissue enriched" "Detected in single" 3721 "lymphoid tissue: 372067.0" "HPA044340, HPA052213, HPA059710" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 67: Testis - Mixed function" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 12 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA044340: , HPA052213: , HPA059710: " "unprognostic (2.27e-3)" "unprognostic (1.62e-1)" "unprognostic (2.55e-1)" "unprognostic (2.61e-2)" "unprognostic (5.91e-3)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.49e-1)" "unprognostic (6.75e-3)" "unprognostic (1.32e-2)" "unprognostic (1.73e-1)" "potential prognostic favorable (8.65e-4)" "unprognostic (1.57e-2)" "unprognostic (1.03e-1)" "unprognostic (5.84e-3)" "unprognostic (4.98e-3)" "unprognostic (2.88e-1)" "unprognostic (4.08e-2)" "unprognostic (2.06e-2)" "unprognostic (2.90e-2)" "unprognostic (3.75e-1)" "unprognostic (8.57e-2)" "unprognostic (9.73e-3)" "unprognostic (2.77e-1)" "unprognostic (2.40e-2)" "unprognostic (2.16e-1)" "unprognostic (1.17e-2)" "unprognostic (3.27e-1)" "unprognostic (3.63e-1)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (8.65e-2)" SURF6 "FLJ30322, RRP14" ENSG00000148296 "Surfeit 6" O75683 9 133328776-133336188 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA-binding, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 10.1;Brain inhibitory neurons: 8.8;Distal convoluted tubule cells: 9.1;Loop of henle epithelial cells: 10.0;Microglia: 13.4;Other brain neurons: 12.7;Paneth cells: 11.6;Papillary tip epithelial cells: 13.3;Proximal tubule cells: 13.7;Renal collecting duct intercalated cells: 9.1;Renal collecting duct principal cells: 9.0;Renal connecting tubule cells: 10.9" "Cell type enhanced" "Detected in many" "Glial cells: 13.4;Neuronal cells: 12.7;Renal nephron cells: 13.7;Secretory gland support: 11.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 12056363.6" "Group enriched" "Detected in some" 23454 "fallopian tube: 1808971.9;lung: 1357883.3;lymphoid tissue: 1609881.6;ovary: 4604768.2" "HPA023608, HPA074622" Approved Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim,Mitotic chromosome" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 98: Neurons - Neurotransmission & signaling" 204 "Nucleoli, Nucleoli rim" "Nucleoplasm, Mitotic chromosome" "HPA023608: , HPA074622: " "unprognostic (1.16e-1)" "unprognostic (1.51e-2)" "unprognostic (1.81e-3)" "unprognostic (7.43e-2)" "unprognostic (1.06e-2)" "unprognostic (8.17e-2)" "unprognostic (1.07e-1)" "potential prognostic favorable (2.61e-4)" "unprognostic (2.08e-1)" "unprognostic (1.76e-1)" "potential prognostic favorable (6.85e-4)" "unprognostic (1.86e-3)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (9.44e-3)" "unprognostic (2.67e-1)" "unprognostic (6.73e-2)" "unprognostic (6.63e-2)" "unprognostic (2.38e-3)" "unprognostic (7.18e-2)" "unprognostic (1.08e-1)" "unprognostic (4.43e-2)" "unprognostic (4.21e-1)" "unprognostic (1.95e-3)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" "unprognostic (4.08e-2)" "unprognostic (3.63e-2)" "unprognostic (4.72e-1)" "unprognostic (1.80e-1)" "potential prognostic favorable (2.47e-5)" SUSD6 KIAA0247 ENSG00000100647 "Sushi domain containing 6" Q92537 14 69611596-69715144 "Predicted membrane proteins" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 4 "Neutrophils: 1672.3" "Cell type enriched" "Detected in all" 4 "Neutrophils: 1672.3" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 549.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Stomach - Gastric mucous cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 114 "Macrophages: 9598.1;Neutrophils: 13196.2" "Tissue enriched" "Detected in some" "bone marrow: 113599.0" "HPA003419, HPA030464" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 49: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 70: DU4475 - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 7 "Plasma membrane" Cytosol "HPA003419: , HPA030464: " "unprognostic (3.46e-2)" "unprognostic (1.88e-1)" "unprognostic (2.34e-1)" "unprognostic (2.45e-1)" "unprognostic (3.99e-2)" "unprognostic (2.00e-1)" "unprognostic (3.33e-1)" "unprognostic (1.25e-1)" "unprognostic (2.82e-1)" "potential prognostic favorable (1.10e-5)" "unprognostic (2.92e-3)" "unprognostic (2.89e-2)" "unprognostic (1.93e-1)" "unprognostic (5.09e-2)" "unprognostic (2.93e-1)" "unprognostic (1.67e-2)" "unprognostic (1.08e-1)" "unprognostic (1.78e-2)" "unprognostic (4.01e-2)" "unprognostic (1.08e-1)" "unprognostic (1.52e-1)" "unprognostic (7.47e-2)" "unprognostic (1.59e-1)" "unprognostic (9.68e-2)" "unprognostic (1.08e-1)" "unprognostic (2.48e-2)" "unprognostic (1.01e-1)" "unprognostic (3.35e-2)" "unprognostic (2.61e-1)" SUZ12 "CHET9, JJAZ1, KIAA0160" ENSG00000178691 "SUZ12 polycomb repressive complex 2 subunit" Q15022 17 31937007-32001038 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Cancer-related genes, Disease variant, Intellectual disability, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 964765.3;T-cells: 1032481.2" "Group enriched" "Detected in some" 11769 "bone marrow: 976036.6;lymphoid tissue: 1377801.5" HPA057436 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 34: B-cells - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 27: Non-specific - Cell proliferation" 107 "Nucleoplasm, Nucleoli, Nuclear bodies" "Nucleoli rim" "HPA057436: " "unprognostic (3.39e-1)" "unprognostic (1.51e-1)" "unprognostic (3.29e-1)" "unprognostic (1.64e-1)" "unprognostic (3.26e-3)" "unprognostic (2.57e-2)" "unprognostic (2.86e-1)" "unprognostic (7.82e-2)" "unprognostic (1.85e-1)" "potential prognostic unfavorable (1.28e-4)" "potential prognostic favorable (2.25e-5)" "unprognostic (1.63e-2)" "unprognostic (5.03e-2)" "unprognostic (2.16e-3)" "potential prognostic unfavorable (3.04e-5)" "unprognostic (1.71e-2)" "unprognostic (5.71e-2)" "unprognostic (5.86e-2)" "unprognostic (7.05e-2)" "unprognostic (3.37e-2)" "unprognostic (6.60e-3)" "unprognostic (2.15e-2)" "unprognostic (6.22e-3)" "unprognostic (4.58e-2)" "unprognostic (4.65e-3)" "unprognostic (1.00e-1)" "unprognostic (1.24e-1)" "unprognostic (1.63e-1)" "unprognostic (2.21e-1)" "unprognostic (4.83e-2)" "unprognostic (3.27e-2)" SVBP "CCDC23, MGC45441" ENSG00000177868 "Small vasohibin binding protein" Q8N300 1 42807052-42817397 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 159.4;Early primary spermatocytes: 140.0;Early spermatids: 147.3;Late primary spermatocytes: 207.3;Oocytes: 147.4;Undifferentiated spermatogonia: 142.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 207.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA008507 Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" "Secreted to blood" "No annotated function" Yes No "Cluster 25: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA008507: " "unprognostic (3.86e-1)" "unprognostic (2.22e-1)" "unprognostic (3.55e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-1)" "unprognostic (2.45e-1)" "unprognostic (5.48e-3)" "unprognostic (1.75e-1)" "unprognostic (1.68e-1)" "potential prognostic favorable (1.70e-4)" "unprognostic (3.08e-2)" "unprognostic (1.53e-2)" "potential prognostic unfavorable (8.45e-7)" "unprognostic (7.07e-2)" "unprognostic (2.97e-2)" "unprognostic (2.53e-2)" "unprognostic (7.43e-2)" "unprognostic (5.97e-2)" "unprognostic (1.53e-1)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (4.21e-1)" "unprognostic (7.92e-2)" "unprognostic (6.65e-2)" "unprognostic (6.22e-3)" "potential prognostic unfavorable (8.22e-4)" "unprognostic (1.01e-1)" "unprognostic (1.11e-2)" "unprognostic (1.37e-1)" SWSAP1 "C19orf39, FLJ35119, SWS1AP1, ZSWIM7AP1" ENSG00000173928 "SWIM-type zinc finger 7 associated protein 1" Q6NVH7 19 11374666-11376951 "Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 32.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA052712 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 48: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 18: Adrenal cortex cells - Steroidogensis" 32 Nucleoplasm Cytosol "HPA052712: " "unprognostic (1.17e-1)" "unprognostic (2.28e-2)" "unprognostic (1.10e-1)" "unprognostic (1.26e-1)" "unprognostic (9.36e-2)" "unprognostic (1.17e-1)" "unprognostic (9.52e-2)" "unprognostic (2.83e-2)" "unprognostic (3.28e-1)" "unprognostic (7.82e-2)" "unprognostic (9.31e-2)" "potential prognostic favorable (2.20e-4)" "unprognostic (3.47e-1)" "unprognostic (1.25e-1)" "unprognostic (2.65e-1)" "unprognostic (9.27e-2)" "unprognostic (1.62e-1)" "unprognostic (6.92e-3)" "unprognostic (1.46e-2)" "unprognostic (2.78e-3)" "unprognostic (8.76e-2)" "unprognostic (1.32e-1)" "unprognostic (4.86e-1)" "unprognostic (2.03e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (1.16e-4)" "unprognostic (2.18e-1)" "unprognostic (2.19e-1)" "unprognostic (8.72e-2)" SYCE1 "bA108K14.6, C10orf94, CT76" ENSG00000171772 "Synaptonemal complex central element protein 1" Q8N0S2 10 133553901-133569835 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" "Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 17.7;testis: 69.5" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 136.9;Early primary spermatocytes: 511.1;Early spermatids: 121.4;Late primary spermatocytes: 262.2;Late spermatids: 131.3;Oocytes: 50.7" "Cell type enriched" "Detected in many" 10 "Spermatogenic cell types: 511.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 23.4" "Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 16114 "Oocytes: 1611446.7" "Not detected" "Not detected" HPA040208 Enhanced Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 30: Non-specific - DNA binding" "Cluster 67: Testis - Mixed function" "Cluster 37: Neurons - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 48 Nucleoplasm "Vesicles, Cytosol" "HPA040208: " "unprognostic (1.38e-2)" "unprognostic (8.47e-2)" "unprognostic (6.39e-3)" "unprognostic (2.83e-1)" "unprognostic (1.56e-1)" "unprognostic (1.02e-2)" "unprognostic (2.30e-1)" "unprognostic (1.80e-2)" "unprognostic (2.63e-1)" "unprognostic (2.55e-2)" "unprognostic (1.68e-1)" "unprognostic (5.23e-1)" "unprognostic (7.09e-2)" "unprognostic (1.34e-1)" "unprognostic (2.53e-1)" "unprognostic (1.22e-2)" SYCE1L MRP2 ENSG00000205078 "Synaptonemal complex central element protein 1 like" A8MT33 16 77199408-77213215 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 17.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 60.3;Breast secretory cells: 167.9;Enteric transient amplifying cells: 70.4;Epididymal efferent duct absorptive cells: 71.0;Late spermatids: 86.3;Paneth cells: 112.2" "Cell type enhanced" "Detected in many" "Secretory cells: 167.9;Secretory gland support: 112.2" "Cell type enhanced" "Detected in many" "CGE interneuron: 22.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enriched" "Detected in single" 73349 "Capillaries: 7334911.0" "Not detected" "Not detected" "HPA062464, HPA066691" Approved "Intermediate filaments" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 21: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 15: Non-specific - Protein processing" "Intermediate filaments" "HPA062464: , HPA066691: " "unprognostic (5.83e-2)" "unprognostic (2.98e-2)" "unprognostic (1.48e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.40e-1)" "unprognostic (3.48e-2)" "unprognostic (1.09e-1)" "unprognostic (3.89e-2)" "validated prognostic unfavorable (3.40e-8)" "validated prognostic unfavorable (3.48e-4)" "unprognostic (3.69e-2)" "unprognostic (4.98e-2)" "unprognostic (5.54e-3)" "unprognostic (4.19e-3)" "unprognostic (1.60e-1)" "unprognostic (2.29e-1)" "unprognostic (2.25e-2)" "unprognostic (5.25e-3)" "unprognostic (7.14e-2)" "unprognostic (1.89e-1)" "unprognostic (3.64e-2)" "unprognostic (1.58e-1)" "unprognostic (1.18e-2)" "unprognostic (4.40e-1)" "unprognostic (8.97e-2)" "unprognostic (9.08e-2)" SYDE2 FLJ13815 ENSG00000097096 "Synapse defective Rho GTPase homolog 2" Q5VT97 1 85156889-85201724 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 7.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 76.7;Cardiomyocytes: 136.7;Corticotrophs: 86.2;Pituicytes/FSCs: 66.9;Retinal pigment epithelial cells: 72.5;Rod photoreceptor cells: 194.6" "Cell type enhanced" "Detected in many" "Myocytes: 136.7;Neuronal cells: 194.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 53.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13859 "Alveolar cell types: 1981986.9;Collecting ducts: 680251.8;Glomeruli: 1505185.0;Proximal tubules: 1376321.5" "Tissue enriched" "Detected in single" 77 "cerebral cortex: 7704.1" "HPA027138, HPA058378" Uncertain Approved "Nucleoli,Nucleoli rim,Golgi apparatus" No No "Cluster 42: Retina - Visual perception" "Cluster 29: Forebrain - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 13 "Nucleoli, Nucleoli rim, Golgi apparatus" "HPA027138: , HPA058378: " "potential prognostic favorable (2.04e-4)" "unprognostic (1.02e-1)" "unprognostic (2.69e-1)" "unprognostic (6.45e-2)" "unprognostic (1.38e-2)" "unprognostic (2.59e-1)" "validated prognostic favorable (9.67e-8)" "validated prognostic favorable (8.90e-4)" "unprognostic (2.67e-1)" "unprognostic (8.09e-3)" "unprognostic (4.65e-2)" "unprognostic (1.97e-2)" "unprognostic (1.35e-2)" "unprognostic (1.05e-1)" "unprognostic (5.10e-1)" "unprognostic (1.52e-1)" "unprognostic (1.69e-2)" "unprognostic (4.68e-2)" "unprognostic (1.42e-1)" "unprognostic (1.88e-1)" "unprognostic (6.86e-2)" SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 69.1;parathyroid gland: 82.3" "Cell type enhanced" "Detected in many" "B-cells: 321.9;cDC: 311.6;Macrophages: 326.0;Microglia: 686.5;Monocyte progenitors: 604.3;monocytes: 415.3;Neutrophil progenitors: 1148.4;Neutrophils: 861.4;pDCs: 312.8" "Cell type enhanced" "Detected in many" "Glial cells: 686.5;Mononuclear phagocytes: 604.3;Neutrophils: 1148.4" "Cell type enriched" "Detected in many" 9 "central nervous system macrophage: 863.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.6;intermediate monocyte: 64.0;memory B-cell: 74.7;myeloid DC: 85.1;naive B-cell: 58.6;neutrophil: 112.4;NK-cell: 30.2;non-classical monocyte: 60.5;plasmacytoid DC: 63.3" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "lymphoma: 87.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Heart muscle - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages, Spleen - B-cells (Spleen), Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 78318757.6" "Tissue enhanced" "Detected in many" "lymphoid tissue: 33331902.5" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 130000 "Cluster 2: Dendritic cells - Unknown function" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 64 "Plasma membrane, Cytosol" Vesicles "CAB007773: , HPA001384: " "unprognostic (6.27e-2)" "unprognostic (2.37e-2)" "unprognostic (4.53e-1)" "unprognostic (5.02e-2)" "unprognostic (2.18e-1)" "unprognostic (2.01e-1)" "unprognostic (1.65e-1)" "unprognostic (2.28e-1)" "unprognostic (6.54e-2)" "unprognostic (2.96e-1)" "unprognostic (5.34e-3)" "unprognostic (1.63e-1)" "unprognostic (6.25e-2)" "unprognostic (1.47e-1)" "unprognostic (2.07e-1)" "unprognostic (2.39e-2)" "unprognostic (7.45e-2)" "unprognostic (6.36e-2)" "unprognostic (2.53e-1)" "unprognostic (6.92e-2)" "unprognostic (5.50e-2)" "unprognostic (4.90e-2)" "unprognostic (1.88e-3)" "unprognostic (2.17e-1)" "unprognostic (5.82e-2)" "unprognostic (3.26e-1)" "unprognostic (2.47e-3)" "unprognostic (1.77e-1)" "unprognostic (2.77e-2)" "unprognostic (1.50e-2)" "unprognostic (1.13e-2)" SYNCRIP "dJ3J17.2, GRY-RBP, hnRNP-Q, HNRNPQ, HNRPQ1, NSAP1" ENSG00000135316 "Synaptotagmin binding cytoplasmic RNA interacting protein" O60506 6 85607779-85644063 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, Translation regulation" "Ribonucleoprotein, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 32.8;Bergmann glia: 42.8;Brain excitatory neurons: 36.8;Brain inhibitory neurons: 35.4;Choroid plexus epithelial cells: 50.0;Distal convoluted tubule cells: 51.4;Ependymal cells: 32.7;Loop of henle epithelial cells: 44.4;Microglia: 74.4;Oligodendrocyte progenitor cells: 44.7;Oligodendrocytes: 50.2;Other brain neurons: 32.5;Papillary tip epithelial cells: 41.8;Podocytes: 34.3;Proximal tubule cells: 54.1;Renal collecting duct intercalated cells: 49.1;Renal collecting duct principal cells: 40.1;Renal connecting tubule cells: 50.0" "Group enriched" "Detected in many" 7 "Ciliated cells: 50.0;Ductal cells: 50.0;Glial cells: 74.4;Neuronal cells: 36.8;Renal nephron cells: 54.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 166183176.2" "Low tissue specificity" "Detected in all" "CAB010895, HPA041275, HPA069241" Supported Uncertain Nucleoplasm,Vesicles,Cytosol NA NA 840000 "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 25: Non-specific - Transcription" "Cluster 28: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 148 Nucleoplasm "Vesicles, Cytosol" "CAB010895: , HPA041275: , HPA069241: " "unprognostic (1.38e-1)" "unprognostic (2.07e-2)" "unprognostic (2.02e-3)" "unprognostic (2.57e-3)" "unprognostic (2.96e-2)" "unprognostic (2.43e-1)" "unprognostic (1.48e-2)" "unprognostic (3.39e-2)" "unprognostic (8.75e-2)" "unprognostic (1.25e-2)" "potential prognostic favorable (8.43e-7)" "unprognostic (4.92e-3)" "unprognostic (3.72e-1)" "potential prognostic unfavorable (3.53e-5)" "unprognostic (3.18e-2)" "unprognostic (5.14e-3)" "unprognostic (6.81e-3)" "unprognostic (3.67e-1)" "unprognostic (2.76e-2)" "unprognostic (3.83e-2)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (4.33e-3)" "unprognostic (1.21e-3)" "unprognostic (9.11e-2)" "unprognostic (3.78e-2)" "unprognostic (1.27e-1)" "unprognostic (9.26e-2)" "unprognostic (9.16e-2)" "unprognostic (9.52e-2)" "unprognostic (2.01e-1)" "unprognostic (7.65e-2)" SYNE2 "DKFZP434H2235, KIAA1011, Nesp2, Nesprin-2, NUA, NUANCE, SYNE-2" ENSG00000054654 "Spectrin repeat containing nuclear envelope protein 2" Q8WXH0 14 63761899-64226433 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Actin-binding "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 185.6" "Cell type enhanced" "Detected in many" "Neutrophils: 1744.6;Proximal tubule cells: 2203.1;Sertoli cells: 2034.3" "Cell type enhanced" "Detected in all" "Renal nephron cells: 2203.1;Reproductive supporting cells: 2034.3" "Group enriched" "Detected in all" 4 "choroid plexus epithelial cell: 681.4;endothelial cell: 707.3;ependymal cell: 182.9;fibroblast: 260.4;leukocyte: 689.5;pericyte: 517.6;vascular associated smooth muscle cell: 665.2" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 4 "choroid plexus: 187.6" "Immune cell enhanced" "Detected in many" "eosinophil: 73.9" "Group enriched" "Detected in many" 11 "granulocytes: 73.9;T-cells: 38.6" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 117702384.1" "Low tissue specificity" "Detected in many" "HPA003435, HPA050204" Enhanced Approved "Nuclear membrane,Intermediate filaments,Primary cilium" No Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 23 "Nuclear membrane, Intermediate filaments" "Primary cilium" "HPA003435: , HPA050204: " "unprognostic (1.48e-1)" "unprognostic (4.28e-2)" "unprognostic (3.47e-1)" "unprognostic (3.04e-2)" "unprognostic (1.80e-1)" "unprognostic (1.07e-1)" "unprognostic (2.10e-1)" "unprognostic (4.82e-3)" "unprognostic (3.44e-1)" "unprognostic (1.84e-2)" "unprognostic (2.46e-2)" "potential prognostic favorable (1.11e-4)" "potential prognostic favorable (3.48e-4)" "unprognostic (2.37e-2)" "unprognostic (8.78e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (2.19e-3)" "unprognostic (5.79e-2)" "unprognostic (1.20e-2)" "unprognostic (4.96e-3)" "unprognostic (3.03e-2)" "unprognostic (6.57e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "unprognostic (1.51e-1)" "unprognostic (9.74e-2)" "unprognostic (2.69e-1)" "unprognostic (5.11e-2)" "unprognostic (1.19e-1)" "unprognostic (6.28e-2)" SYNGAP1 "KIAA1938, RASA5, SYNGAP" ENSG00000197283 "Synaptic Ras GTPase activating protein 1" Q96PV0 6 33419661-33453689 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Autism, Autism spectrum disorder, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 56.7;Bergmann glia: 36.1;Brain excitatory neurons: 57.2;Brain inhibitory neurons: 48.2;Choroid plexus epithelial cells: 119.1;Ependymal cells: 90.7;Oligodendrocyte progenitor cells: 23.7;Other brain neurons: 32.2" "Group enriched" "Detected in many" 4 "Ciliated cells: 119.1;Glial cells: 56.7;Neuronal cells: 57.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 614143 "Astrocytes and Neuropil: 47226375.1;Microglia and Neuropil: 90806416.3;Neurons: 46210022.9" "Tissue enriched" "Detected in many" "cerebral cortex: 56629725.9" "HPA038373, HPA038374" Enhanced Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Intermediate filaments,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA "Cluster 65: Brain - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 35: Neurons - Synaptic function & neurogenesis" 48 "Nucleoplasm, Cytosol" "Nucleoli fibrillar center, Nuclear bodies, Intermediate filaments, Primary cilium, Primary cilium tip, Basal body" "HPA038373: , HPA038374: " "unprognostic (4.87e-2)" "unprognostic (1.12e-1)" "unprognostic (3.96e-1)" "unprognostic (3.33e-3)" "unprognostic (3.62e-3)" "unprognostic (1.07e-1)" "unprognostic (2.59e-1)" "unprognostic (2.57e-1)" "unprognostic (2.52e-2)" "unprognostic (5.41e-2)" "unprognostic (1.98e-2)" "unprognostic (3.20e-2)" "unprognostic (2.97e-2)" "unprognostic (1.54e-1)" "unprognostic (9.37e-3)" "unprognostic (1.59e-1)" "unprognostic (8.49e-2)" "unprognostic (3.85e-2)" "unprognostic (4.73e-3)" "unprognostic (4.04e-1)" "unprognostic (5.18e-2)" "unprognostic (1.25e-3)" "unprognostic (5.90e-2)" "unprognostic (4.88e-3)" "unprognostic (3.54e-1)" "unprognostic (8.23e-2)" "unprognostic (1.21e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (2.15e-1)" SYNGR4 ENSG00000105467 "Synaptogyrin 4" O95473 19 48364367-48376377 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 49.5" "Cell type enhanced" "Detected in some" "Early primary spermatocytes: 197.9;Early spermatids: 34.8;Late primary spermatocytes: 125.8;Late spermatids: 26.9;Pancreatic islet cells: 48.7" "Cell type enriched" "Detected in some" 4 "Spermatogenic cell types: 197.9" "Cell type enhanced" "Detected in some" "upper rhombic lip: 3.0" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 5.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 18.8" "Pancreas - Alpha cells, Pancreas - Beta cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030075, HPA059286" Enhanced Approved "Golgi apparatus" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 35: Non-specific - DNA binding" "Cluster 40: Non-specific - Unknown function" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Golgi apparatus" "HPA030075: , HPA059286: " "unprognostic (2.96e-1)" "unprognostic (2.76e-1)" "unprognostic (4.45e-3)" "unprognostic (1.82e-1)" "unprognostic (3.25e-2)" "unprognostic (2.92e-2)" "unprognostic (4.17e-3)" "unprognostic (1.33e-2)" "unprognostic (1.99e-2)" "unprognostic (7.47e-3)" "unprognostic (1.19e-2)" SYNJ1 "INPP5G, PARK20" ENSG00000159082 "Synaptojanin 1" O43426 21 32628759-32728040 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Endocytosis, Lipid metabolism" "Hydrolase, RNA-binding" "Disease variant, Epilepsy, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.6;retina: 44.8" "Cell type enhanced" "Detected in all" "Choroid plexus epithelial cells: 250.0;Neutrophil progenitors: 404.2;Neutrophils: 455.9;Rod photoreceptor cells: 178.1" "Cell type enhanced" "Detected in all" "Ciliated cells: 250.0;Neutrophils: 455.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 207899986.9;Microglia and Neuropil: 228031083.3;Neurons: 153599842.3" "Tissue enriched" "Detected in many" "cerebral cortex: 257215049.5" HPA011916 Enhanced Approved Nucleoplasm,Centrosome,Cytosol NA NA 2900 "Cluster 35: Neutrophils - Protein binding" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 47: Leukemia - Hemostasis" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 20 "Nucleoplasm, Cytosol" Centrosome "HPA011916: " "unprognostic (7.86e-3)" "unprognostic (1.27e-2)" "unprognostic (1.98e-1)" "unprognostic (1.56e-1)" "unprognostic (1.87e-1)" "unprognostic (4.98e-2)" "unprognostic (6.91e-2)" "unprognostic (1.15e-1)" "potential prognostic favorable (6.41e-4)" "unprognostic (4.22e-2)" "potential prognostic favorable (4.81e-4)" "unprognostic (1.45e-3)" "unprognostic (5.78e-2)" "unprognostic (1.32e-1)" "unprognostic (9.81e-2)" "unprognostic (1.04e-2)" "unprognostic (2.73e-2)" "unprognostic (1.48e-1)" "unprognostic (2.24e-1)" "unprognostic (5.48e-2)" "unprognostic (4.00e-2)" "unprognostic (9.63e-3)" "unprognostic (7.54e-2)" "potential prognostic unfavorable (2.45e-4)" "unprognostic (3.00e-2)" "unprognostic (3.49e-2)" "unprognostic (6.19e-2)" "unprognostic (3.71e-2)" "unprognostic (5.60e-2)" "unprognostic (1.74e-1)" "unprognostic (2.50e-1)" SYNM "DMN, KIAA0353, SYN" ENSG00000182253 Synemin O15061 15 99098217-99135593 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 563.8;skeletal muscle: 585.1;urinary bladder: 445.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 485.7;Breast secretory cells: 126.6;Cardiomyocytes: 129.4;Müller glia: 139.8;Myonuclei: 204.7;Pituicytes/FSCs: 240.3;Retinal pigment epithelial cells: 127.9;Salivary myoepithelial cells: 165.7;Smooth muscle cells: 1015.0;Thymic myoid cells: 213.5;Vascular smooth muscle cells: 229.8" "Cell type enhanced" "Detected in many" "Glial cells: 240.3;Secretory gland support: 485.7;Smooth muscle cells: 1015.0" "Cell type enhanced" "Detected in all" "pericyte: 115.9;vascular associated smooth muscle cell: 117.7" "Cancer enhanced" "Detected in all" "Prostate Adenocarcinoma (TCGA): 61.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "skin cancer: 75.0" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast myoepithelial cells, Colon - Smooth muscle cells, Minor Salivary Gland - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Skeletal myocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 322477673.7;Skeletal myofibers: 1025612509.3" "Group enriched" "Detected in many" "intestine: 2465221362.4;skeletal muscle: 739634894.4;Stomach: 1211187689.9" "CAB017192, HPA040066, HPA044200, HPA077856" Enhanced Supported "Intermediate filaments" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 7 "Intermediate filaments" "CAB017192: , HPA040066: , HPA044200: , HPA077856: " "unprognostic (1.08e-2)" "unprognostic (3.40e-2)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (9.77e-3)" "unprognostic (1.50e-1)" "unprognostic (2.39e-1)" "unprognostic (6.65e-2)" "unprognostic (1.10e-1)" "unprognostic (7.37e-2)" "validated prognostic favorable (2.70e-4)" "validated prognostic favorable (1.40e-5)" "unprognostic (1.20e-1)" "unprognostic (2.50e-2)" "unprognostic (7.74e-2)" "unprognostic (1.04e-1)" "unprognostic (7.31e-2)" "unprognostic (1.21e-2)" "unprognostic (5.45e-2)" "unprognostic (4.02e-2)" "unprognostic (2.42e-1)" "unprognostic (1.03e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.60e-2)" "unprognostic (2.52e-2)" "unprognostic (1.29e-1)" "unprognostic (2.27e-2)" "unprognostic (1.02e-2)" "unprognostic (1.61e-3)" "unprognostic (7.65e-2)" SYNPO KIAA1029 ENSG00000171992 Synaptopodin Q8N3V7 5 150601080-150659207 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "blood vessel: 357.2;heart muscle: 344.8;skeletal muscle: 1214.5;tongue: 468.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 72.7;Cardiomyocytes: 70.9;Colonocytes: 64.1;Enterocytes: 78.7;Myonuclei: 196.5;Pancreatic duct cells: 81.2;Pancreatic islet cells: 92.1;Podocytes: 144.0;Vascular endothelial cells: 93.4;Vascular smooth muscle cells: 79.1" "Cell type enhanced" "Detected in many" "Myocytes: 196.5;Renal nephron cells: 144.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Cancer enriched" "Detected in all" 5 "Kidney cancer: 181.1" "Adrenal gland - Adrenal cortex cells, Breast - Endothelial cells, Heart muscle - Cardiomyocytes, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Spleen - Fibroblasts_1, Stomach - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 266344591.0" "Group enriched" "Detected in all" "blood vessel: 51924107.6;cerebral cortex: 133671090.1;heart muscle: 42734771.7;skeletal muscle: 152276758.9" "CAB033265, HPA034631, CAB037325, HPA071347" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 12 "Plasma membrane, Cytosol" "Actin filaments" "CAB033265: , CAB037325: , HPA034631: , HPA071347: " "unprognostic (1.20e-1)" "unprognostic (7.59e-2)" "unprognostic (9.67e-2)" "potential prognostic unfavorable (4.50e-4)" "unprognostic (1.46e-1)" "unprognostic (4.50e-2)" "unprognostic (4.76e-2)" "potential prognostic unfavorable (3.59e-5)" "unprognostic (3.30e-2)" "unprognostic (2.82e-2)" "unprognostic (5.94e-2)" "unprognostic (3.69e-2)" "unprognostic (6.78e-3)" "unprognostic (1.78e-1)" "potential prognostic favorable (1.44e-5)" "unprognostic (1.17e-3)" "unprognostic (2.96e-1)" "unprognostic (1.49e-2)" "unprognostic (7.17e-3)" "unprognostic (3.95e-2)" "unprognostic (1.39e-2)" "unprognostic (5.16e-2)" "unprognostic (9.33e-2)" "unprognostic (6.40e-2)" "unprognostic (9.66e-3)" "unprognostic (1.24e-1)" "unprognostic (7.36e-3)" "unprognostic (2.84e-2)" "unprognostic (1.05e-1)" "unprognostic (2.26e-1)" "unprognostic (6.60e-2)" SYT4 "HsT1192, KIAA1342" ENSG00000132872 "Synaptotagmin 4" Q9H2B2 18 43267892-43277535 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 140.6" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 63.8;Brain excitatory neurons: 121.9;Brain inhibitory neurons: 55.0;Corticotrophs: 117.1;Epicardial cells: 36.4;Gonadotrophs: 53.8;Lactotrophs: 81.2;Mesothelial cells: 30.1;Other brain neurons: 98.9;Pancreatic islet cells: 132.7;Retinal bipolar cells: 40.2;Somatotrophs: 108.5" "Group enriched" "Detected in some" 4 "Adrenal endocrine cells: 63.8;Barrier epithelial cells: 36.4;Neuronal cells: 121.9;Pancreatic islet cells: 132.7;Pituitary endocrine cells: 117.1" "Cell type enhanced" "Detected in all" "upper rhombic lip: 236.5" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 3.7;Pancreatic Adenocarcinoma (TCGA): 6.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 53.9;prostate cancer: 46.4" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells, Stomach - Gastric enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Microglia and Neuropil: 475790.2;Neurons: 1287200.6" "Tissue enriched" "Detected in single" 961 "cerebral cortex: 96140.4" HPA010574 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 4 "Vesicles, Plasma membrane" "HPA010574: " "unprognostic (4.99e-1)" "unprognostic (1.51e-1)" "unprognostic (3.16e-2)" "unprognostic (3.34e-1)" "unprognostic (9.09e-2)" "unprognostic (1.39e-1)" "unprognostic (5.50e-3)" "unprognostic (1.26e-2)" "unprognostic (8.94e-3)" TACC3 "ERIC-1, ERIC1, maskin, Tacc4" ENSG00000013810 "Transforming acidic coiled-coil containing protein 3" Q9Y6A5 4 1712858-1745171 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 53.1;lymphoid tissue: 48.0;testis: 54.6" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 148.1;Early spermatids: 113.3;Erythrocyte progenitors: 117.7;Late primary spermatocytes: 224.2;Late spermatids: 154.5;Megakaryocytes: 197.8;Monocyte progenitors: 201.6;Neutrophil progenitors: 101.5;Neutrophils: 186.2;Oocytes: 179.6;Platelets: 255.4" "Cell type enhanced" "Detected in many" "Megakaryocytes: 197.8;Mononuclear phagocytes: 201.6;Neutrophils: 186.2;Oocytes: 179.6;Platelets: 255.4;Spermatogenic cell types: 224.2" "Cell type enhanced" "Detected in all" "leukocyte: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 91.1" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 373579.0;Granulosa cells: 1134507.0;Neutrophils: 387597.7;T-cells: 1302896.1" "Group enriched" "Detected in some" 1387 "bone marrow: 141808.2;lymphoid tissue: 135675.4" "HPA005781, HPA006050, CAB010111, HPA022039" Enhanced Approved "Golgi apparatus,Mitotic spindle,Centriolar satellite,Basal body,Cytosol" Yes Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 23: Choroid plexus - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 27: Non-specific - Cell proliferation" 39 "Centriolar satellite, Cytosol" "Golgi apparatus, Mitotic spindle, Basal body" "CAB010111: , HPA005781: , HPA006050: , HPA022039: " "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (8.50e-2)" "unprognostic (4.78e-2)" "unprognostic (4.75e-2)" "unprognostic (2.12e-1)" "unprognostic (1.87e-1)" "unprognostic (1.91e-1)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (8.99e-4)" "validated prognostic unfavorable (1.11e-9)" "validated prognostic unfavorable (1.36e-5)" "potential prognostic unfavorable (1.80e-5)" "validated prognostic unfavorable (1.35e-5)" "validated prognostic unfavorable (3.08e-6)" "validated prognostic unfavorable (8.27e-8)" "validated prognostic unfavorable (3.77e-4)" "unprognostic (6.23e-3)" "unprognostic (7.59e-2)" "unprognostic (1.51e-1)" "unprognostic (2.78e-3)" "unprognostic (1.63e-2)" "unprognostic (3.57e-2)" "unprognostic (1.39e-2)" "unprognostic (1.25e-1)" "unprognostic (4.21e-1)" "unprognostic (3.94e-3)" "unprognostic (1.61e-1)" "unprognostic (3.41e-1)" "unprognostic (1.83e-3)" "unprognostic (7.59e-2)" TACO1 CCDC44 ENSG00000136463 "Translational activator of cytochrome c oxidase I" Q9BSH4 17 63600882-63608365 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Translation regulation" Activator "Leigh syndrome, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 16.5;Enteric stem cells: 14.2;Enteric transient amplifying cells: 20.7;Enterocytes: 35.1;Paneth cells: 15.5;Parietal cells: 14.1;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "Enterocytes: 35.1;Proliferating cells: 20.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Kidney - Proximal tubular cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "intestine: 18261903.4" "HPA021626, HPA021643, HPA024294" Enhanced Enhanced Mitochondria NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 45: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 15: Non-specific - Protein processing" 22 Mitochondria "HPA021626: , HPA021643: , HPA024294: " "unprognostic (4.54e-2)" "unprognostic (7.37e-3)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (3.26e-1)" "unprognostic (4.21e-3)" "unprognostic (2.21e-1)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (5.38e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "unprognostic (3.60e-1)" "unprognostic (6.30e-3)" "unprognostic (2.12e-1)" "unprognostic (9.75e-3)" "potential prognostic unfavorable (5.78e-4)" "unprognostic (2.36e-3)" "unprognostic (3.08e-1)" "unprognostic (1.04e-2)" "unprognostic (5.64e-2)" "unprognostic (1.26e-1)" "unprognostic (1.36e-3)" "unprognostic (1.67e-1)" "unprognostic (5.94e-2)" "unprognostic (5.68e-2)" "unprognostic (6.52e-2)" "unprognostic (3.09e-1)" "unprognostic (2.26e-1)" "unprognostic (3.07e-1)" "unprognostic (2.78e-1)" "unprognostic (4.26e-2)" TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 134.1" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 9.7;Epicardial cells: 6.8;Hepatic stellate cells: 6.5;Retinal horizontal cells: 10.0;Smooth muscle cells: 43.6;Tuft cells: 11.5" "Cell type enhanced" "Detected in many" "Secretory gland support: 11.5;Smooth muscle cells: 43.6" "Cell type enhanced" "Detected in single" "hippocampal CA4: 1.9" "Cancer enhanced" "Detected in many" "Stomach Adenocarcinoma (TCGA): 11.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in some" "Prostate - Smooth muscle cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA076573 Supported "Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 51: Neurons - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 "Plasma membrane" "HPA076573: " "unprognostic (1.38e-1)" "unprognostic (5.33e-2)" "unprognostic (1.60e-1)" "potential prognostic favorable (3.82e-4)" "unprognostic (4.01e-1)" "unprognostic (2.36e-2)" "unprognostic (8.34e-3)" "unprognostic (8.39e-3)" "unprognostic (9.09e-2)" "unprognostic (3.03e-2)" "unprognostic (9.78e-2)" "unprognostic (9.89e-3)" "potential prognostic favorable (1.76e-4)" "unprognostic (6.06e-2)" "unprognostic (8.70e-2)" "unprognostic (4.76e-2)" "unprognostic (1.17e-3)" "unprognostic (7.28e-3)" "unprognostic (3.18e-2)" TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 1245.4;salivary gland: 585.3;skin 1: 554.9" "Cell type enhanced" "Detected in many" "Breast secretory cells: 1810.4;Epididymal basal cells: 7482.4;Esophageal apical cells: 17505.8;Esophageal basal cells: 2063.6;Esophageal suprabasal cells: 5347.3;Ocular epithelial cells: 3288.3;Suprabasal keratinocytes: 2163.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 17505.8;Basal cells: 7482.4;Suprabasal cells: 5347.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 4 "choroid plexus: 3.9;white matter: 1.1" "Immune cell enhanced" "Detected in some" "eosinophil: 15.1" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.1;monocytes: 4.2" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 603.0;head and neck cancer: 792.6" "Liver - Cholangiocytes, Pancreas - Ductal cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" "Collecting ducts: 39656144.8;Keratinocytes: 130337143.7;Large ducts: 112026489.4" "Tissue enhanced" "Detected in many" "lung: 22139708.2;salivary gland: 23989590.1" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 100: Stratified epithelial cells - Barrier functions" 6 "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: , HPA055067: " "unprognostic (1.45e-1)" "unprognostic (5.10e-2)" "unprognostic (7.09e-2)" "unprognostic (2.30e-1)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (6.81e-2)" "potential prognostic favorable (7.73e-5)" "unprognostic (8.69e-2)" "unprognostic (1.52e-1)" "unprognostic (4.31e-2)" "unprognostic (1.37e-1)" "unprognostic (1.21e-2)" "unprognostic (5.84e-2)" "unprognostic (2.56e-2)" "unprognostic (6.29e-2)" "unprognostic (1.62e-3)" "unprognostic (1.61e-2)" "unprognostic (9.31e-2)" "unprognostic (1.34e-2)" "unprognostic (3.26e-1)" "unprognostic (3.51e-1)" "unprognostic (4.11e-1)" "unprognostic (1.58e-1)" "unprognostic (2.05e-1)" "unprognostic (1.43e-1)" "unprognostic (3.42e-1)" "unprognostic (1.49e-2)" "unprognostic (8.16e-2)" TADA1 "ADA1, hADA1, HFI1, STAF42, TADA1L" ENSG00000152382 "Transcriptional adaptor 1" Q96BN2 1 166856510-166876264 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 46.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 605603.9;Neurons: 371239.5;T-cells: 463292.4" "Tissue enriched" "Detected in single" 3682 "lymphoid tissue: 368243.9" HPA028651 Approved Supported "Nucleoplasm,Focal adhesion sites,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 51 Nucleoplasm "Focal adhesion sites, Cytosol" "HPA028651: " "unprognostic (1.61e-2)" "unprognostic (5.02e-3)" "unprognostic (4.45e-2)" "unprognostic (5.42e-2)" "unprognostic (3.69e-2)" "unprognostic (2.82e-1)" "unprognostic (2.05e-1)" "unprognostic (3.17e-1)" "unprognostic (5.01e-2)" "potential prognostic unfavorable (4.54e-7)" "potential prognostic favorable (3.73e-6)" "unprognostic (4.34e-2)" "unprognostic (1.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.33e-3)" "unprognostic (1.09e-1)" "unprognostic (8.04e-3)" "unprognostic (9.45e-2)" "unprognostic (1.45e-1)" "unprognostic (1.32e-1)" "unprognostic (2.37e-2)" "unprognostic (1.23e-1)" "unprognostic (2.85e-1)" "unprognostic (4.55e-2)" "unprognostic (6.04e-2)" "unprognostic (6.60e-2)" "unprognostic (1.15e-1)" "unprognostic (1.02e-1)" "unprognostic (4.81e-2)" "unprognostic (4.50e-2)" "unprognostic (6.72e-2)" TAF1A "SL1, TAFI48" ENSG00000143498 "TATA-box binding protein associated factor, RNA polymerase I subunit A" Q15573 1 222557902-222589933 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 682 "Granulosa cells: 68161.3" "Not detected" "Not detected" HPA054334 Approved Approved "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Primary cilium transition zone,Basal body" NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 7: Non-specific - Transcription" 27 "Nucleoplasm, Microtubules" "Primary cilium, Primary cilium tip, Primary cilium transition zone, Basal body" "HPA054334: " "unprognostic (4.29e-1)" "unprognostic (8.04e-2)" "unprognostic (1.95e-1)" "unprognostic (3.96e-3)" "unprognostic (5.86e-2)" "unprognostic (5.71e-2)" "unprognostic (1.90e-1)" "unprognostic (7.44e-3)" "unprognostic (6.05e-2)" "unprognostic (1.20e-1)" "unprognostic (1.63e-1)" "unprognostic (1.19e-3)" "unprognostic (4.18e-3)" "unprognostic (1.05e-1)" "unprognostic (2.36e-3)" "unprognostic (6.34e-3)" "unprognostic (4.15e-1)" "unprognostic (2.00e-1)" "unprognostic (3.27e-1)" "unprognostic (4.09e-2)" "unprognostic (7.68e-3)" "unprognostic (2.17e-1)" "unprognostic (1.58e-1)" "unprognostic (4.30e-2)" "unprognostic (2.72e-1)" "unprognostic (5.41e-3)" "unprognostic (9.46e-3)" "unprognostic (1.54e-1)" "unprognostic (2.60e-3)" "unprognostic (4.18e-1)" TAF1D "JOSD3, MGC5306, TAF(I)41" ENSG00000166012 "TATA-box binding protein associated factor, RNA polymerase I subunit D" Q9H5J8 11 93729948-93784391 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 549.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030703, HPA055935, HPA060385" Uncertain Supported "Nucleoplasm,Nucleoli,Mitotic spindle,Centriolar satellite" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 54: Non-specific - Ribosome" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 15: Non-specific - Protein processing" 35 Nucleoplasm "Nucleoli, Mitotic spindle, Centriolar satellite" "HPA030703: , HPA055935: , HPA060385: " "unprognostic (6.13e-2)" "unprognostic (2.91e-1)" "unprognostic (2.37e-2)" "unprognostic (3.22e-3)" "unprognostic (5.63e-2)" "unprognostic (2.16e-1)" "unprognostic (2.95e-1)" "potential prognostic favorable (7.79e-4)" "unprognostic (6.61e-2)" "unprognostic (5.43e-2)" "unprognostic (2.87e-3)" "unprognostic (7.66e-2)" "unprognostic (1.97e-2)" "unprognostic (1.79e-2)" "unprognostic (7.26e-3)" "unprognostic (6.19e-2)" "unprognostic (2.30e-3)" "unprognostic (1.61e-1)" "unprognostic (4.18e-1)" "unprognostic (1.88e-1)" "unprognostic (7.25e-2)" "validated prognostic unfavorable (2.73e-4)" "validated prognostic unfavorable (3.98e-4)" "unprognostic (4.66e-2)" "potential prognostic favorable (1.44e-4)" "unprognostic (2.28e-2)" "unprognostic (1.42e-2)" "unprognostic (9.81e-2)" "unprognostic (8.67e-2)" "unprognostic (3.51e-1)" "unprognostic (2.15e-1)" TAGLN "DKFZp686P11128, SM22, SMCC, TAGLN1, WS3-10" ENSG00000149591 Transgelin Q01995 11 117199370-117207464 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 13587.8;intestine: 8800.4" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 8847.7;Decidual stromal cells: 7513.9;Hepatic stellate cells: 8894.7;Pericytes: 3505.4;Peritubular myoid cells: 1928.7;Salivary myoepithelial cells: 2502.0;Smooth muscle cells: 13251.0;Vascular smooth muscle cells: 11546.2" "Group enriched" "Detected in many" 7 "Mural cells: 11546.2;Secretory gland support: 8847.7;Smooth muscle cells: 13251.0;Stellate cells: 8894.7;Stromal cells: 7513.9" "Cell type enriched" "Detected in all" 24 "vascular associated smooth muscle cell: 2667.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "intermediate monocyte: 42.0;non-classical monocyte: 63.9" "Lineage enriched" "Detected in many" 11 "monocytes: 63.9" "Cancer enhanced" "Detected in all" "Bile duct cancer: 653.2;testis cancer: 743.9" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Smooth muscle cells, Heart muscle - Smooth muscle cells, Kidney - Fibroblasts, Lung - Smooth muscle cells, Pituitary gland - Fibroblasts, Prostate - Smooth muscle cells, Skeletal muscle - Smooth muscle cells, Thyroid gland - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Smooth muscle cells: 6669160282.3" "Tissue enhanced" "Detected in all" "intestine: 10537126533.9" "CAB001447, HPA019467, HPA061657" Enhanced Approved Nucleoplasm,Microtubules,Mitochondria,Cytosol No No 6000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 6 "Mitochondria, Cytosol" "Nucleoplasm, Microtubules" "CAB001447: , HPA019467: , HPA061657: " "unprognostic (1.40e-2)" "unprognostic (2.67e-2)" "unprognostic (2.72e-2)" "unprognostic (3.93e-2)" "unprognostic (1.12e-2)" "unprognostic (2.99e-2)" "unprognostic (4.00e-2)" "unprognostic (4.95e-3)" "unprognostic (1.34e-2)" "unprognostic (2.94e-1)" "unprognostic (1.12e-1)" "unprognostic (5.05e-3)" "potential prognostic unfavorable (1.83e-5)" "unprognostic (9.91e-3)" "unprognostic (9.88e-2)" "unprognostic (1.73e-1)" "unprognostic (1.72e-2)" "unprognostic (6.96e-3)" "unprognostic (1.68e-2)" "unprognostic (1.15e-1)" "unprognostic (1.45e-3)" "unprognostic (2.83e-2)" "unprognostic (2.96e-2)" "unprognostic (5.14e-2)" "unprognostic (1.03e-2)" "unprognostic (1.44e-2)" "unprognostic (2.45e-2)" "unprognostic (1.90e-2)" "unprognostic (2.68e-1)" "unprognostic (9.19e-2)" "unprognostic (9.94e-2)" TAL1 "bHLHa17, SCL, TCL5" ENSG00000162367 "TAL bHLH transcription factor 1, erythroid differentiation factor" P17542 1 47216290-47232225 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 28.0" "Cell type enhanced" "Detected in some" "Erythrocyte progenitors: 87.4;Erythrocytes: 54.2;Hematopoietic stem cells: 41.7;Hofbauer cells: 36.6;Lymphatic endothelial cells: 53.5;Mast cells: 42.9;Megakaryocyte progenitors: 70.5;Megakaryocyte-Erythroid progenitors: 71.1;Megakaryocytes: 142.2;Microglia: 159.2;Platelets: 523.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 87.4;Glial cells: 159.2;Megakaryocytes: 142.2;Platelets: 523.7" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 184.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Leukemia: 30.0" "Colon - Endothelial cells, Liver - Vascular endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Stomach - Endothelial cells" "Region enriched" "Detected in many" 5 "midbrain: 14.3" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 283 "Distal tubules: 28269.6" "Tissue enriched" "Detected in single" 7449 "bone marrow: 744874.7" "CAB017805, HPA047866, HPA073983" Approved Enhanced Nucleoplasm Yes NA "Cluster 15: Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 33 Nucleoplasm "CAB017805: , HPA047866: , HPA073983: " "unprognostic (7.58e-2)" "unprognostic (1.08e-1)" "unprognostic (3.00e-1)" "unprognostic (4.80e-2)" "validated prognostic favorable (2.76e-6)" "validated prognostic favorable (5.94e-4)" "potential prognostic favorable (1.80e-4)" "unprognostic (3.20e-2)" "unprognostic (2.82e-1)" "unprognostic (1.68e-2)" "unprognostic (1.54e-1)" TAMALIN GRASP ENSG00000161835 "Trafficking regulator and scaffold protein tamalin" Q7Z6J2 12 52006946-52015889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 84.9;cDC: 162.6;Hematopoietic stem cells: 63.6;Innate lymphoid cells: 116.1;Lymphatic endothelial cells: 64.0;Macrophages: 88.6;Mast cells: 96.6;monocytes: 121.5;NK-cells: 71.3;pDCs: 141.2;Thymocytes: 96.6;Tuft cells: 472.7;Vascular endothelial cells: 162.6" "Cell type enhanced" "Detected in many" "dendritic cells: 162.6;Endothelial cells: 162.6;Secretory gland support: 472.7" "Cell type enhanced" "Detected in many" "endothelial cell: 130.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 18.1" "Breast - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 379125.9" "Group enriched" "Detected in some" 742 "cerebral cortex: 111395.8;lymphoid tissue: 36998.7" "HPA040664, HPA062028" Approved Approved "Nuclear bodies,Vesicles" No NA "Cluster 74: Non-specific - Signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 2 Vesicles "Nuclear bodies" "HPA040664: , HPA062028: " "unprognostic (3.48e-1)" "unprognostic (2.76e-1)" "unprognostic (1.70e-1)" "unprognostic (5.37e-2)" "unprognostic (1.69e-3)" "unprognostic (1.51e-1)" "unprognostic (2.78e-1)" "unprognostic (3.02e-2)" "unprognostic (9.10e-2)" "potential prognostic favorable (9.93e-6)" "unprognostic (1.69e-3)" "unprognostic (3.30e-3)" "unprognostic (4.31e-2)" "unprognostic (2.08e-1)" "unprognostic (9.75e-2)" "unprognostic (8.62e-3)" "unprognostic (1.69e-1)" "unprognostic (1.71e-1)" "unprognostic (1.31e-1)" "unprognostic (1.64e-3)" "unprognostic (8.10e-2)" "unprognostic (5.54e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (3.11e-4)" "unprognostic (8.39e-2)" "unprognostic (5.54e-3)" "unprognostic (3.23e-1)" "unprognostic (3.16e-2)" "unprognostic (1.98e-1)" TAOK2 "hKFC-C, KIAA0881, MAP3K17, PSK, PSK-1, PSK1, PSK1-BETA, TAO1, TAO2, Tao2beta" ENSG00000149930 "TAO kinase 2" Q9UL54 16 29973868-29992261 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Prostate - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "cerebral cortex: 1191602.4" HPA010650 Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 5: Spleen - Immune response" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 14 "Nucleoplasm, Cytosol" Nucleoli "HPA010650: " "unprognostic (1.95e-2)" "unprognostic (3.11e-2)" "unprognostic (3.82e-1)" "unprognostic (7.38e-2)" "unprognostic (2.75e-2)" "unprognostic (1.73e-2)" "unprognostic (2.55e-1)" "potential prognostic favorable (2.29e-6)" "unprognostic (1.23e-2)" "unprognostic (8.84e-2)" "potential prognostic favorable (2.77e-5)" "unprognostic (3.08e-3)" "unprognostic (1.12e-3)" "unprognostic (1.90e-2)" "unprognostic (1.47e-1)" "unprognostic (1.81e-3)" "unprognostic (1.99e-1)" "unprognostic (1.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (8.89e-3)" "unprognostic (2.44e-2)" "unprognostic (2.59e-3)" "unprognostic (9.12e-2)" "unprognostic (1.63e-1)" "unprognostic (1.92e-1)" "unprognostic (9.11e-2)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.08e-1)" TAOK3 "DPK, JIK, MAP3K18" ENSG00000135090 "TAO kinase 3" Q9H2K8 12 118149801-118372907 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hematopoietic stem cells: 1069.4;monocytes: 1082.2;Neutrophil progenitors: 998.5;Neutrophils: 1447.5;Rod photoreceptor cells: 1060.5" "Cell type enhanced" "Detected in all" "Neutrophils: 1447.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "bone marrow: 11030504.8" HPA017160 Approved Uncertain Mitochondria NA NA 260000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 6 Mitochondria "HPA017160: " "unprognostic (1.24e-1)" "unprognostic (1.18e-1)" "unprognostic (7.90e-2)" "unprognostic (5.72e-3)" "unprognostic (2.13e-1)" "unprognostic (1.26e-2)" "unprognostic (3.71e-2)" "potential prognostic favorable (6.66e-4)" "unprognostic (1.60e-1)" "potential prognostic unfavorable (9.16e-4)" "potential prognostic favorable (1.35e-5)" "unprognostic (1.81e-2)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (2.74e-1)" "unprognostic (1.20e-1)" "unprognostic (2.34e-1)" "unprognostic (2.32e-2)" "unprognostic (3.96e-2)" "unprognostic (1.12e-1)" "unprognostic (5.19e-3)" "unprognostic (2.97e-2)" "unprognostic (1.24e-1)" "unprognostic (3.53e-2)" "unprognostic (5.39e-2)" "unprognostic (3.99e-1)" "unprognostic (1.08e-1)" "unprognostic (2.26e-1)" "unprognostic (4.42e-1)" "unprognostic (6.72e-2)" "unprognostic (1.25e-2)" TAPT1 FLJ90013 ENSG00000169762 "Transmembrane anterior posterior transformation 1" Q6NXT6 4 16160505-16227410 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Chondrogenesis, Cilium biogenesis/degradation, Differentiation, Host-virus interaction, Osteogenesis" "Developmental protein, Receptor" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 299.4;Myonuclei: 204.1;Neutrophil progenitors: 230.0" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 299.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Pancreas - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" HPA042567 Approved Supported "Nucleoplasm,Centrosome,Basal body,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 4 "Centrosome, Basal body" "Nucleoplasm, Cytosol" "HPA042567: " "potential prognostic favorable (4.72e-4)" "unprognostic (1.48e-1)" "unprognostic (1.69e-2)" "unprognostic (2.48e-1)" "unprognostic (1.58e-2)" "unprognostic (8.90e-2)" "unprognostic (2.33e-1)" "unprognostic (5.77e-3)" "unprognostic (5.53e-2)" "unprognostic (2.25e-1)" "validated prognostic favorable (4.38e-6)" "validated prognostic favorable (2.10e-6)" "unprognostic (6.68e-3)" "unprognostic (1.21e-2)" "potential prognostic favorable (1.50e-4)" "potential prognostic favorable (3.20e-4)" "unprognostic (1.88e-1)" "unprognostic (6.55e-2)" "unprognostic (2.48e-1)" "unprognostic (3.22e-2)" "unprognostic (1.33e-1)" "potential prognostic favorable (1.80e-4)" "unprognostic (4.59e-3)" "unprognostic (6.78e-2)" "unprognostic (3.14e-2)" "unprognostic (9.81e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (5.15e-2)" "unprognostic (1.35e-3)" "unprognostic (5.09e-2)" TARS1 TARS ENSG00000113407 "Threonyl-tRNA synthetase 1" P26639 5 33440696-33468091 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Pancreas epithelial cells: 123023766.7;Pancreatic islets: 217555372.3" "Tissue enriched" "Detected in all" "pancreas: 212532550.8" HPA037425 Approved Approved "Actin filaments,Cytosol" NA NA 1300000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 29: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 16 Cytosol "Actin filaments" "HPA037425: " "unprognostic (4.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.11e-2)" "unprognostic (1.88e-1)" "unprognostic (1.09e-2)" "unprognostic (1.02e-2)" "unprognostic (3.42e-1)" "unprognostic (1.06e-2)" "potential prognostic unfavorable (4.79e-4)" "potential prognostic favorable (1.14e-7)" "unprognostic (1.35e-1)" "unprognostic (6.14e-2)" "unprognostic (3.15e-3)" "unprognostic (1.16e-2)" "potential prognostic unfavorable (2.30e-4)" "unprognostic (2.01e-1)" "unprognostic (3.12e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-1)" "unprognostic (1.77e-2)" "potential prognostic unfavorable (7.55e-6)" "unprognostic (2.63e-3)" "unprognostic (1.46e-2)" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (9.84e-2)" "unprognostic (1.08e-1)" "unprognostic (2.02e-2)" "unprognostic (3.87e-1)" TARS2 "FLJ12528, TARSL1" ENSG00000143374 "Threonyl-tRNA synthetase 2, mitochondrial" Q9BW92 1 150487414-150507602 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" HPA028626 Approved Uncertain Nucleoplasm,Cytosol NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 51: Secretory epithelial cells - Mixed function" 48 "Nucleoplasm, Cytosol" "HPA028626: " "unprognostic (5.83e-2)" "unprognostic (5.64e-2)" "unprognostic (2.96e-2)" "unprognostic (1.50e-1)" "unprognostic (9.12e-2)" "unprognostic (6.48e-3)" "unprognostic (7.26e-2)" "unprognostic (8.79e-2)" "unprognostic (2.24e-1)" "unprognostic (3.51e-3)" "unprognostic (1.05e-2)" "unprognostic (2.06e-1)" "unprognostic (1.86e-1)" "unprognostic (5.76e-3)" "unprognostic (2.14e-1)" "unprognostic (1.33e-2)" "unprognostic (5.19e-3)" "unprognostic (1.65e-1)" "unprognostic (5.08e-2)" "unprognostic (8.32e-2)" "unprognostic (1.89e-1)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (1.20e-1)" "unprognostic (4.01e-2)" "unprognostic (1.28e-2)" "unprognostic (3.54e-2)" "unprognostic (1.73e-1)" "unprognostic (1.43e-1)" "unprognostic (2.50e-2)" TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825219-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" 4 "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (2.74e-1)" "unprognostic (6.89e-2)" TASL "CXorf21, FLJ11577" ENSG00000120280 "TLR adaptor interacting with endolysosomal SLC15A4" Q9HAI6 X 30558809-30577766 "Disease related genes, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.4;lymphoid tissue: 10.2" "Cell type enhanced" "Detected in some" "cDC: 66.3;Hofbauer cells: 35.2;Kupffer cells: 29.7;Macrophages: 43.6;Microglia: 35.4;Monocyte progenitors: 149.0;monocytes: 48.2;Neutrophil progenitors: 32.5;Neutrophils: 58.6;pDCs: 71.4;Plasma cells: 61.3;Thymocytes: 36.4" "Cell type enhanced" "Detected in some" "dendritic cells: 71.4;Mononuclear phagocytes: 149.0;Neutrophils: 58.6;Plasma cells: 61.3" "Cell type enriched" "Detected in some" 5 "central nervous system macrophage: 43.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 86 "Leukemia: 43.1;lymphoma: 17.3;Myeloma: 20.4" "Adrenal gland - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA001185 Uncertain Supported Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 8 Nucleoplasm "Vesicles, Cytosol" "HPA001185: " "unprognostic (3.85e-2)" "unprognostic (3.74e-1)" "unprognostic (5.15e-2)" "unprognostic (8.76e-3)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (5.78e-3)" "unprognostic (3.46e-2)" "unprognostic (1.44e-1)" "unprognostic (3.37e-1)" "unprognostic (1.99e-1)" "potential prognostic favorable (1.64e-5)" "unprognostic (4.95e-2)" "unprognostic (1.73e-1)" "unprognostic (1.91e-1)" "unprognostic (1.96e-1)" "unprognostic (6.40e-2)" "unprognostic (2.31e-1)" "unprognostic (2.63e-2)" "unprognostic (1.38e-2)" "unprognostic (1.71e-1)" "unprognostic (1.39e-1)" "unprognostic (8.33e-3)" "unprognostic (2.94e-2)" "unprognostic (3.66e-3)" TASP1 "C20orf13, dJ585I14.2, FLJ20212" ENSG00000089123 "Taspase 1" Q9H6P5 20 13389392-13638932 "Disease related genes, Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 27.3" "Cell type enriched" "Detected in all" 4 "Thymocytes: 1666.8" "Cell type enriched" "Detected in all" 4 "T-cells: 1666.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 57053.1;Macrophages: 52701.5" "Group enriched" "Detected in many" "lymphoid tissue: 515259.7;ovary: 154908.9" "HPA030824, HPA030825" Uncertain Approved "Plasma membrane" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 59: Leukemia - T-cell receptor" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Plasma membrane" "HPA030824: , HPA030825: " "unprognostic (6.97e-2)" "unprognostic (1.39e-1)" "unprognostic (2.38e-1)" "unprognostic (2.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.58e-1)" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (8.41e-2)" "unprognostic (4.77e-2)" "unprognostic (1.13e-3)" "unprognostic (1.16e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (8.16e-4)" "unprognostic (1.50e-3)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (3.98e-2)" "unprognostic (2.33e-1)" "unprognostic (5.91e-3)" "unprognostic (2.75e-1)" "unprognostic (3.22e-1)" "potential prognostic unfavorable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (2.65e-2)" "unprognostic (3.93e-2)" "unprognostic (9.25e-2)" "unprognostic (2.67e-1)" "unprognostic (1.45e-1)" "unprognostic (7.06e-3)" "unprognostic (4.28e-2)" TBC1D14 KIAA1322 ENSG00000132405 "TBC1 domain family member 14" Q9P2M4 4 6909242-7033118 "Plasma proteins, Predicted intracellular proteins" Autophagy "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Mast cells: 277.5;Neutrophils: 894.7;Renal collecting duct intercalated cells: 872.3" "Cell type enhanced" "Detected in all" "Ductal cells: 872.3;Neutrophils: 894.7" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in all" 6 "Kidney Chromophobe (TCGA): 377.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Macrophages, Adrenal gland - Adrenal cortex cells, Colon - Macrophages, Stomach - Parietal cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Proximal tubules: 626910.6" "Tissue enriched" "Detected in some" "bone marrow: 522172.4" "HPA036930, HPA067398" Approved Supported "Nucleoplasm,Golgi apparatus,Vesicles" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 3 "Golgi apparatus, Vesicles" Nucleoplasm "HPA036930: , HPA067398: " "unprognostic (8.21e-2)" "unprognostic (1.65e-3)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (2.54e-4)" "unprognostic (8.70e-3)" "unprognostic (3.79e-2)" "unprognostic (4.48e-1)" "potential prognostic favorable (1.87e-4)" "unprognostic (1.02e-3)" "unprognostic (3.79e-2)" "potential prognostic favorable (2.27e-6)" "unprognostic (2.22e-3)" "unprognostic (4.19e-3)" "unprognostic (1.58e-2)" "unprognostic (1.65e-1)" "unprognostic (3.66e-2)" "unprognostic (1.48e-3)" "unprognostic (2.84e-2)" "unprognostic (8.38e-2)" "unprognostic (9.59e-2)" "unprognostic (2.65e-1)" "unprognostic (1.92e-3)" "unprognostic (1.57e-1)" "unprognostic (4.20e-2)" "unprognostic (4.96e-3)" "unprognostic (1.29e-1)" "unprognostic (6.60e-2)" "unprognostic (9.83e-2)" "unprognostic (2.99e-1)" "unprognostic (6.22e-2)" "unprognostic (2.35e-2)" TBC1D21 "MGC34741, MgcRabGAP" ENSG00000167139 "TBC1 domain family member 21" Q8IYX1 15 73873564-73889214 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 465 "testis: 46.4" "Group enriched" "Detected in some" 5 "Early spermatids: 475.1;Late spermatids: 1706.8" "Cell type enriched" "Detected in some" 664 "Spermatogenic cell types: 1706.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA043319 Enhanced Approved "Calyx,Mid piece" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 70: DU4475 - Unknown function" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 16 "Calyx, Mid piece" "HPA043319: " TBC1D4 "AS160, DKFZp779C0666, KIAA0603" ENSG00000136111 "TBC1 domain family member 4" O60343 13 75283503-75482169 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "GTPase activation" "Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 77.5" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 1167.5;Cardiomyocytes: 601.2;Loop of henle epithelial cells: 544.5;Microglia: 456.5;Myonuclei: 961.0;Pituicytes/FSCs: 540.2;Renal collecting duct intercalated cells: 792.9;Thymic myoid cells: 509.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 1167.5;Ductal cells: 792.9;Myocytes: 961.0" "Cell type enhanced" "Detected in all" "endothelial cell: 1520.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 25.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 26409219.7" "Low tissue specificity" "Detected in all" "HPA040145, HPA059885" Approved Enhanced Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 47: Endothelial cells - Vasculature" "Cluster 19: Non-specific - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 39 Cytosol "HPA040145: , HPA059885: " "potential prognostic favorable (8.58e-5)" "unprognostic (8.81e-3)" "unprognostic (3.26e-2)" "unprognostic (3.02e-1)" "unprognostic (2.94e-1)" "unprognostic (8.42e-3)" "unprognostic (1.10e-1)" "unprognostic (7.15e-2)" "unprognostic (1.90e-3)" "unprognostic (1.21e-2)" "potential prognostic favorable (7.05e-8)" "unprognostic (3.45e-3)" "potential prognostic favorable (5.92e-4)" "unprognostic (4.89e-3)" "unprognostic (1.98e-1)" "unprognostic (1.93e-1)" "unprognostic (1.96e-1)" "unprognostic (8.79e-2)" "unprognostic (8.12e-3)" "unprognostic (5.02e-2)" "unprognostic (3.00e-1)" "unprognostic (1.20e-1)" "unprognostic (3.65e-1)" "unprognostic (2.89e-1)" "unprognostic (2.22e-2)" "unprognostic (3.95e-3)" "unprognostic (2.13e-1)" "unprognostic (3.76e-2)" "unprognostic (4.32e-2)" "unprognostic (3.59e-2)" "unprognostic (1.02e-2)" TBL1X "EBI, TBL1" ENSG00000101849 "Transducin beta like 1 X-linked" O60907 X 9463320-9741037 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" Activator "Congenital hypothyroidism, Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 696.7;Gonadotrophs: 800.9;Neutrophils: 1835.5;Somatotrophs: 689.4" "Cell type enhanced" "Detected in all" "Neutrophils: 1835.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 19.1" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Testis - Sertoli cells" "Cell type enriched" "Detected in many" "B-cells: 3589551.0" "Group enriched" "Detected in some" 339 "lymphoid tissue: 21666.2;ovary: 46229.5" "CAB005363, HPA067703" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 Nucleoplasm Nucleoli "CAB005363: , HPA067703: " "unprognostic (5.17e-3)" "unprognostic (4.00e-3)" "unprognostic (8.78e-3)" "unprognostic (1.32e-1)" "unprognostic (2.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.05e-1)" "unprognostic (7.62e-2)" "unprognostic (9.71e-2)" "unprognostic (7.81e-2)" "potential prognostic favorable (2.90e-8)" "unprognostic (7.88e-2)" "unprognostic (4.57e-2)" "unprognostic (1.97e-3)" "unprognostic (2.00e-1)" "unprognostic (1.54e-1)" "unprognostic (4.79e-2)" "unprognostic (1.70e-2)" "unprognostic (2.33e-3)" "unprognostic (4.39e-1)" "unprognostic (3.56e-1)" "unprognostic (1.33e-3)" "unprognostic (3.85e-2)" "unprognostic (2.73e-1)" "unprognostic (2.12e-1)" "unprognostic (2.88e-2)" "unprognostic (1.09e-1)" "unprognostic (1.39e-1)" "unprognostic (9.99e-2)" "unprognostic (2.28e-3)" "unprognostic (5.90e-2)" TCEAL1 "p21, pp21, SIIR, WEX9" ENSG00000172465 "Transcription elongation factor A like 1" Q15170 X 103628704-103630953 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 270.0;Leydig cells: 243.8;Ovarian stromal cells: 245.9;Peritubular myoid cells: 365.2;Smooth muscle cells: 238.6" "Cell type enhanced" "Detected in all" "Leydig cells: 243.8;Smooth muscle cells: 238.6;Stromal cells: 365.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in all" 4 "Adrenocortical cancer: 128.7" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Microglia and Neuropil: 54001.7;Neurons: 39844.7" "Tissue enriched" "Detected in some" "ovary: 8333687.6" "HPA057345, HPA060384, HPA076762" Approved Enhanced Nucleoplasm No No "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 94: Gonadal somatic cells - Mixed function" 6 Nucleoplasm "HPA057345: , HPA060384: , HPA076762: " "potential prognostic favorable (3.13e-4)" "unprognostic (1.44e-2)" "unprognostic (1.29e-2)" "unprognostic (1.41e-2)" "unprognostic (1.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (1.32e-1)" "unprognostic (2.76e-2)" "potential prognostic favorable (2.35e-9)" "unprognostic (3.23e-3)" "unprognostic (2.15e-1)" "unprognostic (2.84e-1)" "unprognostic (2.02e-1)" "unprognostic (3.53e-2)" "unprognostic (2.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.62e-1)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (2.73e-2)" "unprognostic (3.69e-2)" "unprognostic (1.89e-1)" "unprognostic (6.50e-2)" "unprognostic (2.36e-1)" "unprognostic (1.27e-2)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (1.59e-1)" "unprognostic (1.02e-1)" TCEAL3 "MGC15737, WEX8" ENSG00000196507 "Transcription elongation factor A like 3" Q969E4 X 103607451-103629690 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 349.2;Epididymal basal cells: 195.5;Epididymal principal cells: 196.5;Ovarian stromal cells: 260.7;Peritubular myoid cells: 234.3;Smooth muscle cells: 319.4" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 319.4;Stromal cells: 349.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_2" "Cell type enriched" "Detected in single" 33 "Glomeruli: 3334.9" "Tissue enhanced" "Detected in many" "ovary: 29857866.3" "HPA045564, HPA058982" Uncertain Uncertain Nucleoplasm NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 6: Non-specific - Immune response" "Cluster 36: Non-specific - mRNA processing" "Cluster 62: Smooth muscle cells - Muscle contraction" 1 Nucleoplasm "HPA045564: , HPA058982: " "potential prognostic favorable (1.62e-6)" "unprognostic (5.82e-2)" "unprognostic (1.56e-2)" "unprognostic (2.28e-1)" "unprognostic (6.51e-2)" "unprognostic (2.11e-1)" "unprognostic (1.14e-1)" "unprognostic (2.26e-1)" "unprognostic (7.36e-3)" "unprognostic (6.94e-2)" "unprognostic (3.37e-3)" "unprognostic (1.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.18e-1)" "unprognostic (6.39e-2)" "unprognostic (8.23e-3)" "unprognostic (5.08e-2)" "unprognostic (1.16e-1)" "unprognostic (5.60e-2)" "unprognostic (6.22e-2)" "unprognostic (8.63e-2)" "potential prognostic favorable (3.03e-4)" "unprognostic (2.18e-1)" "unprognostic (3.28e-1)" "unprognostic (1.89e-2)" "unprognostic (7.66e-2)" "unprognostic (4.88e-1)" "unprognostic (2.45e-2)" "unprognostic (1.30e-1)" "unprognostic (1.84e-1)" "unprognostic (2.14e-1)" TCEAL5 WEX4 ENSG00000204065 "Transcription elongation factor A like 5" Q5H9L2 X 103273691-103276750 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 113.7;pituitary gland: 67.3;testis: 65.5" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 18.9;Lactotrophs: 18.3;Late spermatids: 25.2;Müller glia: 53.5;Other brain neurons: 16.5;Pancreatic islet cells: 18.4;Peritubular myoid cells: 26.9;Pituicytes/FSCs: 16.8;Retinal amacrine cells: 28.4;Retinal bipolar cells: 25.8;Sertoli cells: 110.8;Somatotrophs: 16.1" "Cell type enhanced" "Detected in many" "Glial cells: 53.5;Neuronal cells: 28.4;Reproductive supporting cells: 110.8" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 27.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Neuroblastoma: 24.3" "Adrenal gland - Adrenal medulla cells, Lung - Fibroblasts_2, Minor Salivary Gland - Smooth muscle cells, Pancreas - Alpha cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Cell type enriched" "Detected in single" 166 "Neurons: 16626.9" "Tissue enriched" "Detected in some" "cerebral cortex: 21040047.0" "HPA045564, HPA058982" Supported Approved Nucleoplasm NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 2 Nucleoplasm "HPA045564: , HPA058982: " "unprognostic (2.35e-1)" "unprognostic (2.73e-2)" "unprognostic (1.94e-2)" "unprognostic (2.31e-1)" "unprognostic (8.86e-2)" "unprognostic (3.38e-3)" "unprognostic (2.12e-1)" "potential prognostic favorable (4.38e-4)" "unprognostic (5.39e-3)" "unprognostic (2.36e-1)" "unprognostic (4.02e-1)" TCEAL6 WEX2 ENSG00000204071 "Transcription elongation factor A like 6" Q6IPX3 X 102140476-102142970 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 95.6;pituitary gland: 67.7;testis: 25.1" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 21.9;Brain inhibitory neurons: 20.0;Corticotrophs: 12.3;Gonadotrophs: 30.5;Granulosa cells: 38.9;Lactotrophs: 26.8;Other brain neurons: 36.9;Pituicytes/FSCs: 25.0;Retinal amacrine cells: 17.6;Retinal bipolar cells: 21.9;Sertoli cells: 43.3;Smooth muscle cells: 18.5;Somatotrophs: 24.9;Thyrotrophs: 22.1" "Cell type enhanced" "Detected in some" "Glial cells: 25.0;Neuronal cells: 36.9;Pituitary endocrine cells: 30.5;Reproductive supporting cells: 43.3;Smooth muscle cells: 18.5" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in single" 12 "Glioblastoma Multiforme (TCGA): 8.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Minor Salivary Gland - Smooth muscle cells, Skin - Eccrine sweat gland cells, Testis - Sertoli cells" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 754181.7;Neurons: 2035227.9" "Tissue enhanced" "Detected in some" "cerebral cortex: 3613798.8;ovary: 7461235.3" "HPA045564, HPA058982" Supported Uncertain Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "HPA045564: , HPA058982: " "unprognostic (3.17e-3)" "unprognostic (7.36e-2)" TCEAL7 "MGC23947, WEX5" ENSG00000182916 "Transcription elongation factor A like 7" Q9BRU2 X 103330229-103332326 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 120.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 35.9;Brain inhibitory neurons: 34.6;Breast myoepithelial cells: 55.1;Decidual stromal cells: 78.6;Endometrial stromal cells: 35.5;Fibroblasts: 34.2;Granulosa cells: 51.1;Müller glia: 88.0;Oligodendrocytes: 45.2;Other brain neurons: 71.6;Ovarian stromal cells: 64.5;Peritubular myoid cells: 36.0;Pituicytes/FSCs: 32.7;Retinal amacrine cells: 38.3;Retinal horizontal cells: 34.1;Schwann cells: 32.4;Smooth muscle cells: 30.7" "Cell type enhanced" "Detected in many" "Glial cells: 88.0;Neuronal cells: 71.6;Reproductive supporting cells: 51.1;Secretory gland support: 55.1;Stromal cells: 78.6" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 11 "Glioblastoma Multiforme (TCGA): 76.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Brain cancer: 16.8;Neuroblastoma: 58.0;Sarcoma: 16.5" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Kidney - Fibroblasts, Liver - Hepatic stellate cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2639 "Astrocytes and Neuropil: 206619.7;Neurons: 321232.9" "Not detected" "Not detected" "HPA051507, HPA065080" Enhanced Supported Nucleoplasm NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" Nucleoplasm "HPA051507: , HPA065080: " "unprognostic (2.03e-2)" "unprognostic (8.01e-2)" "unprognostic (3.63e-2)" "unprognostic (8.82e-2)" "unprognostic (3.49e-2)" "unprognostic (2.35e-1)" "unprognostic (1.41e-1)" "unprognostic (1.55e-1)" "unprognostic (2.26e-2)" "unprognostic (7.30e-2)" "unprognostic (4.61e-3)" "unprognostic (3.24e-3)" "unprognostic (1.33e-2)" "unprognostic (2.16e-2)" "unprognostic (4.95e-3)" "unprognostic (1.82e-1)" "unprognostic (5.28e-2)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (1.38e-3)" "unprognostic (3.90e-1)" "unprognostic (5.64e-2)" "unprognostic (2.68e-2)" "unprognostic (1.66e-1)" "unprognostic (1.32e-1)" "potential prognostic unfavorable (1.06e-4)" "unprognostic (1.72e-1)" "unprognostic (4.06e-2)" "unprognostic (1.28e-1)" TCF3 "bHLHb21, E2A, E47, ITF1, MGC129647, MGC129648, p75, VDIR" ENSG00000071564 "Transcription factor 3" P15923 19 1609291-1652615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 128.5;Plasma cells: 96.0;Undifferentiated spermatogonia: 119.2" "Cell type enhanced" "Detected in many" "Erythrocytes: 128.5;Spermatogenic cell types: 119.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Liver - Vascular endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7463 "B-cells: 864319.8;Granulosa cells: 715034.1;Macrophages: 626652.5;Oocytes: 779391.8" "Tissue enriched" "Detected in some" "lymphoid tissue: 1162380.1" "CAB018351, HPA049808, HPA062476" Approved Enhanced Nucleoplasm No No "Cluster 17: B-cells - Immunoglobulins" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 48 Nucleoplasm "CAB018351: , HPA049808: , HPA062476: " "unprognostic (1.46e-2)" "unprognostic (5.15e-2)" "unprognostic (5.11e-1)" "unprognostic (2.48e-3)" "unprognostic (3.57e-1)" "unprognostic (5.16e-2)" "unprognostic (2.23e-2)" "unprognostic (9.37e-3)" "unprognostic (4.99e-2)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (6.60e-5)" "unprognostic (6.19e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (2.92e-2)" "unprognostic (1.81e-1)" "unprognostic (1.24e-3)" "unprognostic (7.72e-2)" "unprognostic (4.70e-3)" "unprognostic (2.89e-1)" "unprognostic (8.32e-2)" "unprognostic (1.43e-1)" "unprognostic (1.38e-3)" "unprognostic (9.58e-3)" "unprognostic (5.65e-2)" "unprognostic (7.06e-3)" "unprognostic (1.40e-1)" "unprognostic (3.95e-2)" "unprognostic (1.75e-1)" "unprognostic (2.42e-1)" "potential prognostic favorable (3.90e-4)" TCF7L2 "TCF-4, TCF4" ENSG00000148737 "Transcription factor 7 like 2" Q9NQB0 10 112950247-113167678 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 890.0;Extravillous trophoblasts: 978.6;Foveolar cells: 1101.0;Kupffer cells: 1068.0" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 873.4;thalamic excitatory: 827.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "thalamus: 379.6" "Group enriched" "Detected in many" 7 "intermediate monocyte: 24.2;non-classical monocyte: 61.8" "Lineage enriched" "Detected in many" 11 "monocytes: 61.8" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Spleen - Macrophages" "Group enriched" "Detected in all" 9 "midbrain: 67.2;thalamus: 86.6" "Group enriched" "Detected in all" 4 "midbrain: 194.2;pons: 127.6;thalamus: 215.0" "Cell type enriched" "Detected in single" 441 "Large ducts: 44114.8" "Not detected" "Not detected" "CAB013535, HPA038800" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 38: Sub-cortical - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 47 Nucleoplasm "Nuclear bodies, Cytosol" "CAB013535: , HPA038800: " "potential prognostic favorable (6.22e-4)" "unprognostic (3.34e-2)" "unprognostic (8.87e-2)" "unprognostic (3.62e-2)" "unprognostic (3.36e-1)" "unprognostic (7.42e-2)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "unprognostic (2.87e-1)" "unprognostic (1.50e-1)" "validated prognostic favorable (9.23e-8)" "validated prognostic favorable (2.72e-5)" "unprognostic (2.81e-1)" "unprognostic (2.05e-1)" "unprognostic (8.66e-3)" "unprognostic (1.08e-1)" "unprognostic (5.46e-3)" "unprognostic (8.78e-2)" "unprognostic (2.26e-1)" "unprognostic (5.86e-2)" "unprognostic (1.39e-1)" "unprognostic (5.43e-3)" "unprognostic (1.77e-2)" "unprognostic (6.38e-3)" "unprognostic (3.33e-1)" "unprognostic (3.85e-1)" "unprognostic (1.19e-1)" "unprognostic (2.99e-1)" "unprognostic (1.72e-1)" "unprognostic (1.42e-1)" "unprognostic (7.01e-2)" TCHP "MGC10854, TpMs" ENSG00000139437 "Trichoplein keratin filament binding" Q9BT92 12 109900264-109983841 "Predicted intracellular proteins" "Apoptosis, Cilium biogenesis/degradation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 253.5;Epicardial cells: 177.4" "Cell type enhanced" "Detected in all" "Myocytes: 253.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 1805378.6" "Tissue enriched" "Detected in some" "fallopian tube: 619797.3" "HPA038638, HPA061543" Supported Approved "Plasma membrane,Primary cilium,Centrosome,Basal body,Cytosol,Mid piece,Principal piece" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 2: Non-specific - Mixed function" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 63 "Plasma membrane, Cytosol" "Primary cilium, Centrosome, Basal body, Mid piece, Principal piece" "HPA038638: , HPA061543: " "unprognostic (1.29e-1)" "unprognostic (8.47e-2)" "unprognostic (2.29e-1)" "unprognostic (1.51e-1)" "unprognostic (2.22e-1)" "unprognostic (8.00e-2)" "unprognostic (1.79e-1)" "unprognostic (9.22e-2)" "unprognostic (6.43e-2)" "unprognostic (9.25e-2)" "unprognostic (1.12e-2)" "unprognostic (6.48e-2)" "unprognostic (1.68e-1)" "unprognostic (1.02e-3)" "unprognostic (3.34e-2)" "unprognostic (1.23e-1)" "unprognostic (3.36e-1)" "unprognostic (2.01e-1)" "unprognostic (3.07e-2)" "unprognostic (1.15e-1)" "unprognostic (3.62e-1)" "unprognostic (9.11e-3)" "unprognostic (2.85e-1)" "unprognostic (1.55e-1)" "unprognostic (8.42e-2)" "unprognostic (2.42e-1)" "unprognostic (3.31e-2)" "unprognostic (2.65e-2)" "unprognostic (1.78e-1)" "unprognostic (1.35e-1)" "unprognostic (1.44e-1)" TCL1A TCL1 ENSG00000100721 "TCL1 family AKT coactivator A" P56279 14 95709947-95714196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "lymphoid tissue: 249.5" "Cell type enriched" "Detected in some" 4 "pDCs: 735.5" "Cell type enriched" "Detected in some" 4 "dendritic cells: 735.5" "Cell type enriched" "Detected in single" 31 "leukocyte: 3.1" "Cancer enriched" "Detected in many" 21 "Testicular Germ Cell Tumor (TCGA): 189.5" "Not detected" "Not detected" "Group enriched" "Detected in many" 295 "memory B-cell: 879.8;naive B-cell: 2165.4;plasmacytoid DC: 1102.9" "Group enriched" "Detected in all" 348 "B-cells: 2165.4;dendritic cells: 1102.9" "Group enriched" "Detected in some" 187 "Leukemia: 214.5;lymphoma: 528.5" "Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" "B-cells: 7564516.1;Oocytes: 2456713.8;T-cells: 3107687.6" "Group enriched" "Detected in some" "bone marrow: 4120209.2;lymphoid tissue: 8986659.1" "CAB004045, HPA016604" Enhanced Enhanced "Nucleoplasm,Endoplasmic reticulum,Cytosol" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 50 "Endoplasmic reticulum, Cytosol" Nucleoplasm "CAB004045: , HPA016604: " "unprognostic (1.09e-1)" "unprognostic (1.86e-3)" "unprognostic (5.76e-3)" "unprognostic (3.65e-1)" "unprognostic (6.79e-2)" "potential prognostic favorable (6.88e-4)" "potential prognostic favorable (9.56e-4)" "unprognostic (1.21e-2)" "unprognostic (2.75e-2)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "unprognostic (2.60e-2)" "unprognostic (1.44e-1)" "unprognostic (2.27e-1)" "unprognostic (2.44e-1)" TCTE1 "D6S46, DRC5, FAP155, MGC33600" ENSG00000146221 "T-complex-associated-testis-expressed 1" Q5JU00 6 44278734-44297698 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 7.9;fallopian tube: 13.6;testis: 28.4" "Group enriched" "Detected in some" 4 "Early spermatids: 181.5;Late spermatids: 534.6" "Cell type enriched" "Detected in some" 9 "Spermatogenic cell types: 534.6" "Cell type enriched" "Detected in many" 6 "ependymal cell: 27.4" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Neuroblastoma: 2.6" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 33047 "Fallopian tube cells: 3304655.4" "Tissue enriched" "Detected in single" 7508 "fallopian tube: 750829.1" HPA031739 Approved "Vesicles,Cytosol,Mid piece" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 2: Neurons - Nucleosome" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Vesicles, Mid piece" Cytosol "HPA031739: " "unprognostic (1.41e-1)" "unprognostic (2.60e-1)" "unprognostic (2.25e-2)" TCTN1 "FLJ21127, JBTS13, TECT1" ENSG00000204852 "Tectonic family member 1" Q2MV58 12 110614027-110663431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.9" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 149.2;Ependymal cells: 148.7;Epididymal efferent duct ciliated cells: 191.8;Fallopian tube ciliated cells: 304.4;Respiratory ciliated cells: 278.3" "Cell type enhanced" "Detected in all" "Ciliated cells: 304.4" "Cell type enhanced" "Detected in all" "ependymal cell: 167.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 2075069.7;Granulosa cells: 681208.1;Oocytes: 849583.3" "Group enriched" "Detected in some" 1729 "fallopian tube: 201847.0;ovary: 143861.9" "HPA039687, HPA040036" Approved Approved "Nucleoplasm,Actin filaments,Primary cilium" "Intracellular and membrane" "Developmental protein" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 "Actin filaments, Primary cilium" Nucleoplasm "HPA039687: , HPA040036: " "unprognostic (2.21e-1)" "unprognostic (6.27e-2)" "unprognostic (2.09e-1)" "unprognostic (8.77e-2)" "unprognostic (1.35e-1)" "unprognostic (4.09e-2)" "unprognostic (2.14e-2)" "unprognostic (4.13e-3)" "unprognostic (1.28e-1)" "unprognostic (8.82e-3)" "unprognostic (2.71e-2)" "unprognostic (1.05e-1)" "unprognostic (5.67e-2)" "unprognostic (3.85e-2)" "unprognostic (1.87e-1)" "unprognostic (5.34e-2)" "unprognostic (6.74e-2)" "unprognostic (9.70e-3)" "unprognostic (1.91e-1)" "unprognostic (8.89e-2)" "unprognostic (1.83e-1)" "unprognostic (3.21e-1)" "unprognostic (3.09e-3)" "unprognostic (1.61e-1)" "unprognostic (1.51e-1)" "unprognostic (2.27e-1)" "unprognostic (1.84e-1)" "unprognostic (1.27e-2)" "unprognostic (8.36e-2)" "unprognostic (5.74e-2)" "unprognostic (6.48e-2)" TCTN2 "C12orf38, FLJ12975, JBTS24, MKS8, TECT2" ENSG00000168778 "Tectonic family member 2" Q96GX1 12 123671110-123708399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 37.2" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 49.6;Endometrial ciliated cells: 45.7;Ependymal cells: 72.4;Fallopian tube ciliated cells: 62.5;Respiratory ciliated cells: 82.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 82.4" "Cell type enhanced" "Detected in all" "ependymal cell: 87.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Fallopian tube cells: 3931959.2;Pancreatic islets: 5078803.1" "Tissue enriched" "Detected in single" 10212 "fallopian tube: 1021188.0" HPA039900 Enhanced Approved "Golgi apparatus,Microtubules,Primary cilium transition zone" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 41 "Golgi apparatus, Microtubules" "Primary cilium transition zone" "HPA039900: " "unprognostic (8.29e-2)" "unprognostic (1.43e-1)" "unprognostic (3.57e-2)" "unprognostic (1.60e-1)" "unprognostic (7.09e-2)" "unprognostic (3.82e-2)" "unprognostic (2.07e-2)" "potential prognostic unfavorable (5.91e-4)" "unprognostic (1.91e-1)" "unprognostic (7.10e-3)" "unprognostic (1.23e-3)" "unprognostic (3.62e-1)" "unprognostic (8.35e-3)" "unprognostic (1.99e-3)" "unprognostic (1.19e-2)" "unprognostic (1.33e-1)" "unprognostic (1.27e-2)" "unprognostic (9.08e-2)" "unprognostic (1.63e-1)" "unprognostic (2.92e-1)" "unprognostic (2.12e-1)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (2.00e-2)" "unprognostic (2.51e-1)" "unprognostic (4.22e-2)" "unprognostic (2.56e-2)" "unprognostic (2.08e-1)" "unprognostic (4.23e-1)" "unprognostic (3.92e-2)" "unprognostic (1.58e-1)" TDG ENSG00000139372 "Thymine DNA glycosylase" Q13569 12 103965822-103988874 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA052263 Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 31 Nucleoplasm "Plasma membrane" "HPA052263: " "unprognostic (6.50e-2)" "unprognostic (8.22e-2)" "unprognostic (2.81e-1)" "unprognostic (2.99e-1)" "unprognostic (3.19e-2)" "unprognostic (1.83e-2)" "unprognostic (1.43e-1)" "unprognostic (2.20e-1)" "unprognostic (5.89e-2)" "unprognostic (8.81e-3)" "unprognostic (8.47e-2)" "unprognostic (8.31e-2)" "potential prognostic unfavorable (2.49e-4)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (2.35e-3)" "potential prognostic unfavorable (8.13e-4)" "unprognostic (9.85e-3)" "unprognostic (1.05e-1)" "unprognostic (7.19e-3)" "unprognostic (8.64e-2)" "unprognostic (2.52e-3)" "unprognostic (2.01e-1)" "unprognostic (3.98e-3)" "unprognostic (3.07e-2)" "unprognostic (2.52e-1)" "unprognostic (4.01e-2)" "unprognostic (9.44e-2)" "unprognostic (3.64e-1)" "unprognostic (3.64e-1)" "unprognostic (2.54e-2)" "unprognostic (3.07e-1)" TDO2 "TDO, TPH2" ENSG00000151790 "Tryptophan 2,3-dioxygenase" P48775 4 155854738-155920406 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "liver: 739.5" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 166.6" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 166.6" "Cell type enhanced" "Detected in many" "hippocampal dentate gyrus: 64.3;thalamic excitatory: 63.7" "Cancer enriched" "Detected in many" 15 "Liver Hepatocellular Carcinoma (TCGA): 101.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Pituitary gland - Gonadotropes" "Group enriched" "Detected in some" 7 "cerebellum: 6.3;hippocampal formation: 5.3;white matter: 1.9" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 9846 "Hepatocytes: 984595.4" "Tissue enriched" "Detected in single" 255 "liver: 25548.9" HPA039611 Uncertain Approved "Plasma membrane,Primary cilium,Basal body,Cytosol" NA NA "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 53: Neurons - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 27 "Plasma membrane, Cytosol" "Primary cilium, Basal body" "HPA039611: " "unprognostic (1.69e-2)" "unprognostic (5.86e-2)" "unprognostic (8.75e-2)" "unprognostic (2.70e-2)" "unprognostic (7.83e-2)" "unprognostic (8.73e-2)" "unprognostic (1.70e-3)" "unprognostic (5.02e-2)" "unprognostic (3.61e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-3)" "unprognostic (8.11e-3)" "unprognostic (2.21e-1)" "unprognostic (1.89e-3)" "unprognostic (6.76e-2)" "unprognostic (2.10e-3)" "unprognostic (4.66e-2)" "unprognostic (4.13e-1)" "unprognostic (3.67e-2)" "unprognostic (1.46e-2)" "unprognostic (1.50e-1)" "unprognostic (1.06e-2)" "unprognostic (3.92e-1)" "unprognostic (1.34e-1)" "unprognostic (1.08e-2)" "unprognostic (1.40e-1)" "unprognostic (4.90e-2)" "unprognostic (3.40e-2)" TDP1 "FLJ11090, SCAN1" ENSG00000042088 "Tyrosyl-DNA phosphodiesterase 1" Q9NUW8 14 89954939-90044764 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 165.8;Late primary spermatocytes: 100.2;Oocytes: 78.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 165.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - B-cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1311655.7;Neurons: 1271392.4;T-cells: 1734406.5" "Group enriched" "Detected in some" "bone marrow: 746521.5;lymphoid tissue: 310630.3" HPA071317 Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 27 Nucleoplasm "Plasma membrane" "HPA071317: " "unprognostic (3.20e-2)" "unprognostic (2.92e-1)" "unprognostic (3.48e-1)" "unprognostic (1.83e-3)" "unprognostic (5.21e-3)" "unprognostic (3.27e-2)" "unprognostic (7.24e-2)" "unprognostic (3.78e-3)" "unprognostic (7.09e-2)" "unprognostic (4.80e-3)" "potential prognostic favorable (8.10e-5)" "unprognostic (2.60e-1)" "unprognostic (1.94e-1)" "potential prognostic unfavorable (2.45e-5)" "unprognostic (2.28e-2)" "potential prognostic unfavorable (1.87e-4)" "unprognostic (4.07e-2)" "unprognostic (1.76e-2)" "unprognostic (3.28e-1)" "unprognostic (4.31e-2)" "unprognostic (2.80e-2)" "unprognostic (2.71e-2)" "unprognostic (1.42e-1)" "unprognostic (6.47e-2)" "potential prognostic favorable (3.43e-4)" "unprognostic (8.47e-2)" "unprognostic (3.33e-2)" "unprognostic (2.19e-1)" "unprognostic (1.47e-1)" "unprognostic (2.28e-3)" "unprognostic (1.32e-1)" TDP2 TTRAP ENSG00000111802 "Tyrosyl-DNA phosphodiesterase 2" O95551 6 24649979-24666930 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction" "Hydrolase, Nuclease" "Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 172.6" "Cell type enhanced" "Detected in many" "Colonocytes: 526.7;Early spermatids: 197.3;Enterocytes: 656.8;Goblet cells: 222.1;Neutrophils: 336.8" "Cell type enhanced" "Detected in all" "Enterocytes: 656.8;Neutrophils: 336.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 75.8;neutrophil: 229.6" "Lineage enriched" "Detected in all" 7 "granulocytes: 229.6" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Prostate - Prostate glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 1314371.8;Proximal tubules: 1314847.6" "Tissue enhanced" "Detected in many" "bone marrow: 3202751.5" "CAB073398, HPA074011" Enhanced Supported "Nucleoplasm,Nuclear bodies" "Intracellular and membrane" Enzyme No No "Cluster 35: Neutrophils - Protein binding" "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 13 "Nucleoplasm, Nuclear bodies" "CAB073398: , HPA074011: " "unprognostic (6.71e-2)" "unprognostic (1.59e-2)" "unprognostic (8.05e-2)" "unprognostic (2.89e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (5.31e-5)" "unprognostic (9.58e-2)" "unprognostic (1.19e-1)" "unprognostic (4.53e-2)" "unprognostic (7.37e-3)" "potential prognostic favorable (6.13e-8)" "unprognostic (1.01e-3)" "unprognostic (3.26e-2)" "unprognostic (2.12e-3)" "unprognostic (1.04e-1)" "unprognostic (7.72e-2)" "unprognostic (1.59e-1)" "unprognostic (1.45e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (3.00e-4)" "unprognostic (8.30e-3)" "unprognostic (7.87e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (5.04e-4)" "unprognostic (8.56e-2)" "potential prognostic unfavorable (7.97e-5)" "potential prognostic unfavorable (3.28e-4)" "unprognostic (1.21e-1)" "unprognostic (1.09e-1)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" TDRD10 DKFZp434M202 ENSG00000163239 "Tudor domain containing 10" Q5VZ19 1 154502219-154548147 "Cancer-related genes, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 52.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 84.4;Early spermatids: 173.4;Kupffer cells: 41.0;Late primary spermatocytes: 139.6;Late spermatids: 331.7;Mesothelial cells: 38.2;Undifferentiated spermatogonia: 47.5;Vascular endothelial cells: 43.6" "Cell type enriched" "Detected in many" 7 "Spermatogenic cell types: 331.7" "Cell type enriched" "Detected in some" 4 "endothelial cell: 51.7" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 7.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 2.2" "Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells, Skin - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Skeletal myofibers: 5735464.5" "Low tissue specificity" "Detected in all" HPA054327 Approved Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 4: Non-specific - Transcription" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" Vesicles "HPA054327: " "unprognostic (1.57e-2)" "unprognostic (8.03e-2)" "unprognostic (1.22e-1)" "unprognostic (5.62e-2)" "unprognostic (2.27e-1)" "unprognostic (5.25e-3)" "potential prognostic favorable (2.26e-4)" "unprognostic (2.23e-1)" "unprognostic (3.74e-1)" "unprognostic (5.39e-3)" TEAD4 "EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1" ENSG00000197905 "TEA domain transcription factor 4" Q15561 12 2959330-3040676 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 122.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 63.1;Cytotrophoblasts: 85.0;Migrating cytotrophoblasts: 81.2;Myonuclei: 139.1;Pancreatic acinar cells: 81.9;Salivary myoepithelial cells: 63.6;Thymic myoid cells: 61.2;Vascular endothelial cells: 76.0" "Cell type enhanced" "Detected in many" "Myocytes: 139.1" "Group enriched" "Detected in some" 4 "endothelial cell: 46.5;vascular associated smooth muscle cell: 15.7" "Cancer enriched" "Detected in all" 5 "Testicular Germ Cell Tumor (TCGA): 179.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Skin - Keratinocyte (granular), Testis - Spermatogonia" "Region enriched" "Detected in single" 5 "cerebellum: 3.1" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 85 "Pancreas epithelial cells: 8514.3" "Not detected" "Not detected" HPA056896 Uncertain Supported Nucleoplasm NA NA "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 12: Non-specific - Vasculature" "Cluster 38: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 50 Nucleoplasm "HPA056896: " "unprognostic (2.74e-1)" "unprognostic (2.01e-1)" "unprognostic (4.07e-1)" "unprognostic (2.40e-1)" "unprognostic (3.29e-1)" "unprognostic (3.64e-2)" "unprognostic (9.75e-2)" "unprognostic (2.55e-2)" "unprognostic (1.98e-1)" "unprognostic (7.12e-2)" "unprognostic (5.05e-3)" "unprognostic (3.34e-2)" "unprognostic (1.78e-1)" "unprognostic (5.94e-3)" "unprognostic (1.58e-1)" "unprognostic (1.64e-3)" "potential prognostic unfavorable (1.36e-4)" "unprognostic (3.42e-1)" "unprognostic (2.17e-2)" "unprognostic (9.98e-2)" "unprognostic (1.13e-1)" "unprognostic (3.64e-3)" "unprognostic (2.18e-2)" "unprognostic (4.78e-2)" "unprognostic (1.74e-1)" "unprognostic (1.46e-2)" "unprognostic (4.22e-2)" "unprognostic (1.50e-2)" "unprognostic (2.32e-1)" "unprognostic (9.87e-3)" "unprognostic (7.04e-2)" TEDC1 C14orf80 ENSG00000185347 "Tubulin epsilon and delta complex 1" Q86SX3 14 105489855-105499575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 26.5;Enteric transient amplifying cells: 29.2;Esophageal basal cells: 22.6;Extravillous trophoblasts: 32.4;Monocyte progenitors: 22.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Fallopian tube cells: 101732.6;Oocytes: 172154.2" "Not detected" "Not detected" "HPA039049, HPA039050" Uncertain Uncertain "Nucleoplasm,Golgi apparatus,Cytosol" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 65: Non-specific - Cell growth & division" 8 "Golgi apparatus" "Nucleoplasm, Cytosol" "HPA039049: , HPA039050: " "unprognostic (4.02e-2)" "unprognostic (1.57e-1)" "unprognostic (6.46e-2)" "unprognostic (2.61e-1)" "unprognostic (1.99e-1)" "unprognostic (5.68e-2)" "unprognostic (1.11e-2)" "unprognostic (9.90e-2)" "unprognostic (2.01e-2)" "unprognostic (1.23e-1)" "unprognostic (1.12e-1)" "unprognostic (1.17e-1)" "potential prognostic unfavorable (5.23e-4)" "unprognostic (7.22e-3)" "unprognostic (2.40e-1)" "unprognostic (8.27e-2)" "unprognostic (5.55e-2)" "unprognostic (2.02e-1)" "unprognostic (4.20e-2)" "unprognostic (8.65e-2)" "unprognostic (1.65e-1)" "unprognostic (3.42e-1)" "unprognostic (7.35e-2)" "unprognostic (2.75e-1)" "unprognostic (4.89e-2)" "unprognostic (1.19e-1)" "unprognostic (1.20e-2)" "unprognostic (1.78e-2)" "unprognostic (2.06e-1)" TEFM "C17orf42, FLJ22729" ENSG00000172171 "Transcription elongation factor, mitochondrial" Q96QE5 17 30897336-30906238 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 5050907.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 196337.5" "HPA023788, HPA053044" Approved Enhanced Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 16 Mitochondria "HPA023788: , HPA053044: " "unprognostic (5.96e-2)" "unprognostic (7.70e-3)" "unprognostic (2.41e-2)" "potential prognostic favorable (4.34e-4)" "unprognostic (6.30e-2)" "unprognostic (1.03e-1)" "unprognostic (6.69e-2)" "unprognostic (2.78e-1)" "unprognostic (2.72e-1)" "unprognostic (1.96e-3)" "unprognostic (1.40e-1)" "unprognostic (1.95e-3)" "potential prognostic unfavorable (9.74e-5)" "unprognostic (1.30e-2)" "unprognostic (3.03e-1)" "unprognostic (1.56e-2)" "unprognostic (5.17e-3)" "unprognostic (1.66e-1)" "unprognostic (5.03e-2)" "unprognostic (1.43e-1)" "unprognostic (1.19e-3)" "unprognostic (1.32e-1)" "unprognostic (2.08e-3)" "potential prognostic favorable (8.31e-5)" "unprognostic (7.93e-3)" "unprognostic (7.90e-2)" "unprognostic (9.82e-2)" "unprognostic (2.64e-1)" "unprognostic (2.90e-1)" TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 43.5" "Group enriched" "Detected in many" 6 "Lymphatic endothelial cells: 124.0;Oligodendrocyte progenitor cells: 141.9;Vascular endothelial cells: 321.2" "Group enriched" "Detected in many" 8 "Endothelial cells: 321.2;Glial cells: 141.9" "Group enriched" "Detected in all" 8 "endothelial cell: 417.7;oligodendrocyte precursor cell: 143.8" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 13.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "Rhabdoid: 17.5;testis cancer: 16.9" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Adrenal gland - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Lung - Endothelial cells, Minor Salivary Gland - Endothelial cells, Pituitary gland - Endothelial cells, Prostate - Endothelial cells, Skeletal muscle - Endothelial cells, Spleen - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cell types: 540869.1;Glomeruli: 1521486.2" "Group enriched" "Detected in some" "liver: 47187.6;lung: 114240.3;lymphoid tissue: 64758.3" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centrosome,Basal body" "Secreted to blood" Receptor NA NA 7750000 3100000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 47: Endothelial cells - Vasculature" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 14 "Plasma membrane" "Centrosome, Basal body" "CAB010359: , HPA073265: " "unprognostic (2.08e-1)" "unprognostic (3.02e-1)" "unprognostic (7.64e-3)" "unprognostic (4.21e-2)" "unprognostic (3.16e-2)" "unprognostic (5.78e-2)" "unprognostic (2.56e-1)" "unprognostic (8.83e-3)" "unprognostic (4.71e-3)" "unprognostic (3.04e-1)" "validated prognostic favorable (3.45e-13)" "validated prognostic favorable (5.48e-5)" "unprognostic (4.39e-3)" "validated prognostic favorable (1.01e-4)" "validated prognostic favorable (8.49e-4)" "unprognostic (2.27e-2)" "unprognostic (3.43e-2)" "unprognostic (6.68e-2)" "unprognostic (1.65e-1)" "unprognostic (1.82e-1)" "unprognostic (7.71e-2)" "unprognostic (1.10e-2)" "unprognostic (1.11e-1)" "unprognostic (1.48e-1)" "unprognostic (6.37e-2)" "unprognostic (1.74e-2)" "unprognostic (3.60e-3)" "unprognostic (3.71e-2)" "unprognostic (5.25e-2)" "unprognostic (6.63e-2)" TEKT3 FLJ32828 ENSG00000125409 "Tektin 3" Q9BXF9 17 15303811-15341632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 29.9" "Group enriched" "Detected in many" 5 "Early spermatids: 520.4;Late primary spermatocytes: 227.3;Late spermatids: 574.9" "Cell type enriched" "Detected in many" 7 "Spermatogenic cell types: 574.9" "Cell type enriched" "Detected in many" 7 "ependymal cell: 52.3" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 2.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.7" "Cancer enriched" "Detected in single" 7 "testis cancer: 2.5" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 380510 "Fallopian tube cells: 38050983.3" "Tissue enriched" "Detected in single" 122488 "fallopian tube: 12248766.7" "HPA044354, HPA073565" Enhanced Supported "Equatorial segment,Calyx,Mid piece,Principal piece,End piece" NA NA "Cluster 47: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 55: Lymphoma - Immune response" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 28 "Mid piece, Principal piece, End piece" "Equatorial segment, Calyx" "HPA044354: , HPA073565: " "unprognostic (3.04e-1)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (2.98e-1)" "unprognostic (1.96e-1)" TENM2 "KIAA1127, ODZ2, Ten-M2, TEN2" ENSG00000145934 "Teneurin transmembrane protein 2" Q9NT68 5 166979029-168264157 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "heart muscle: 32.8" "Cell type enhanced" "Detected in many" "Astrocytes: 890.1;Bergmann glia: 873.8;Brain excitatory neurons: 1896.6;Brain inhibitory neurons: 1690.2;Cardiomyocytes: 730.4;Choroid plexus epithelial cells: 1452.1;Medullary thymic epithelial cells: 684.1;Other brain neurons: 1167.8;Peritubular myoid cells: 621.7;Podocytes: 873.2;Retinal amacrine cells: 1215.6;Retinal ganglion cells: 1672.6;Retinal horizontal cells: 2708.6;Thymic myoid cells: 1352.8" "Cell type enhanced" "Detected in all" "Ciliated cells: 1452.1;Glial cells: 890.1;Neuronal cells: 2708.6;Renal nephron cells: 873.2;Stromal cells: 1352.8" "Cell type enhanced" "Detected in all" "mammillary body: 6183.6" "Group enriched" "Detected in many" 5 "Head and Neck Squamous Cell Carcinoma (TCGA): 25.7;Lung Squamous Cell Carcinoma (TCGA): 8.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 25.6;Brain cancer: 25.6" "Heart muscle - Cardiomyocytes, Kidney - Podocytes, Prostate - Smooth muscle cells, Skin - Inner root sheath cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5026 "Astrocytes and Neuropil: 525416.1;Microglia and Neuropil: 537032.1;Neurons: 445221.9" "Tissue enriched" "Detected in single" 461430 "cerebral cortex: 46143007.4" "HPA038018, HPA038420, HPA068691" Uncertain Approved Nucleoli No No 21000 "Cluster 35: Non-specific - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 109: Neurons - Neuronal signaling" Nucleoli "HPA038018: , HPA038420: , HPA068691: " "unprognostic (1.38e-2)" "unprognostic (2.06e-1)" "unprognostic (3.50e-1)" "unprognostic (1.12e-2)" "unprognostic (3.34e-1)" "unprognostic (6.77e-3)" "unprognostic (5.37e-2)" "unprognostic (3.68e-2)" "unprognostic (1.18e-1)" "unprognostic (3.29e-2)" TENT2 "FLJ38499, GLD2, PAPD4, TUT2" ENSG00000164329 "Terminal nucleotidyltransferase 2" Q6PIY7 5 79612120-79688246 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "mRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 700445.6;T-cells: 695296.8" "Tissue enriched" "Detected in some" "lymphoid tissue: 923704.3" HPA054468 Approved Cytosol No No "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 5 Cytosol "HPA054468: " "potential prognostic favorable (3.49e-4)" "unprognostic (1.87e-1)" "unprognostic (2.97e-2)" "unprognostic (4.09e-2)" "unprognostic (9.27e-2)" "unprognostic (2.24e-1)" "unprognostic (3.29e-1)" "unprognostic (1.03e-2)" "unprognostic (1.45e-3)" "unprognostic (1.13e-3)" "unprognostic (1.03e-2)" "unprognostic (3.02e-2)" "unprognostic (1.41e-2)" "unprognostic (1.25e-1)" "unprognostic (8.70e-3)" "unprognostic (3.57e-1)" "unprognostic (1.49e-1)" "unprognostic (6.06e-3)" "unprognostic (1.64e-2)" "unprognostic (1.48e-1)" "unprognostic (1.92e-3)" "unprognostic (1.48e-1)" "unprognostic (8.41e-2)" "unprognostic (1.79e-1)" "unprognostic (2.69e-2)" "unprognostic (9.00e-2)" "unprognostic (1.91e-1)" "unprognostic (6.34e-3)" "unprognostic (1.57e-1)" TENT4A "LAK-1, PAPD7, POLK, POLS, TRF4, TRF4-1" ENSG00000112941 "Terminal nucleotidyltransferase 4A" Q5XG87 5 6713432-6757044 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA processing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045487, HPA046742" Enhanced Supported "Nucleoplasm,Nuclear membrane,Golgi apparatus" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 2: Neurons - Nucleosome" "Cluster 29: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 1 Nucleoplasm "Nuclear membrane, Golgi apparatus" "HPA045487: , HPA046742: " "unprognostic (2.12e-1)" "unprognostic (1.47e-2)" "unprognostic (1.36e-1)" "unprognostic (9.47e-2)" "unprognostic (2.14e-1)" "unprognostic (1.38e-1)" "unprognostic (7.14e-2)" "unprognostic (3.95e-3)" "unprognostic (3.77e-2)" "unprognostic (4.51e-1)" "unprognostic (1.76e-1)" "unprognostic (7.98e-2)" "unprognostic (6.59e-2)" "unprognostic (2.09e-1)" "potential prognostic unfavorable (9.51e-4)" "unprognostic (2.16e-1)" "potential prognostic favorable (5.64e-4)" "unprognostic (2.56e-1)" "unprognostic (1.08e-2)" "unprognostic (4.32e-2)" "potential prognostic unfavorable (6.62e-4)" "unprognostic (7.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.31e-1)" "unprognostic (4.03e-1)" "unprognostic (3.76e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-2)" "unprognostic (1.48e-3)" TERB2 "C15orf43, MGC33951" ENSG00000167014 "Telomere repeat binding bouquet formation protein 2" Q8NHR7 15 44956687-44979229 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 20.5" "Group enriched" "Detected in some" 8 "Early primary spermatocytes: 118.6;Late primary spermatocytes: 243.9" "Cell type enriched" "Detected in some" 11 "Spermatogenic cell types: 243.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Liver - Hepatocytes, Skin - Sebaceous gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA041780 Uncertain Nucleoplasm,Nucleoli No NA "Cluster 57: Testis - Spermatogenesis" "Cluster 18: Liver cancer - Metabolism" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Nucleoli Nucleoplasm "HPA041780: " TERF2 "TRBF2, TRF2" ENSG00000132604 "Telomeric repeat binding factor 2" Q15554 16 69355567-69408571 "Essential proteins, Predicted intracellular proteins" "Cell cycle" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 4043073.9" "Group enriched" "Detected in many" "intestine: 995103.9;lymphoid tissue: 2015855.2" "HPA001907, HPA002735, CAB010451, CAB080271" Enhanced Supported "Nucleoplasm,Nuclear bodies" NA NA "Cluster 34: B-cells - Unknown function" "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Transcription" 90 "Nucleoplasm, Nuclear bodies" "CAB010451: , CAB080271: , HPA001907: , HPA002735: " "unprognostic (3.31e-3)" "unprognostic (3.10e-2)" "unprognostic (1.39e-1)" "unprognostic (7.75e-2)" "unprognostic (1.37e-1)" "unprognostic (2.75e-2)" "unprognostic (1.72e-1)" "unprognostic (4.27e-3)" "unprognostic (9.46e-2)" "unprognostic (4.58e-3)" "validated prognostic favorable (3.08e-4)" "validated prognostic favorable (7.99e-4)" "unprognostic (1.86e-1)" "unprognostic (6.24e-3)" "unprognostic (1.18e-1)" "unprognostic (1.38e-1)" "unprognostic (5.61e-3)" "unprognostic (2.62e-2)" "unprognostic (7.81e-3)" "unprognostic (1.08e-1)" "unprognostic (6.40e-3)" "unprognostic (2.57e-1)" "unprognostic (5.30e-2)" "unprognostic (9.41e-3)" "unprognostic (1.20e-1)" "unprognostic (2.77e-1)" "unprognostic (5.29e-2)" "unprognostic (1.31e-1)" "unprognostic (2.87e-1)" "unprognostic (9.38e-3)" "unprognostic (1.83e-2)" TERT "EST2, hEST2, TCS1, TP2, TRT" ENSG00000164362 "Telomerase reverse transcriptase" O14746 5 1253147-1295068 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "DNA-binding, Nucleotidyltransferase, Ribonucleoprotein, RNA-directed DNA polymerase, Transferase" "Cancer-related genes, Disease variant, Dyskeratosis congenita" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 11.8;Early primary spermatocytes: 11.0;Enteric stem cells: 2.7;Enteric transient amplifying cells: 2.8;Goblet cells: 2.7;Paneth cells: 3.9;Plasma cells: 5.4;Respiratory ionocytes: 2.5;Undifferentiated spermatogonia: 9.6" "Cell type enhanced" "Detected in some" "Plasma cells: 5.4;Secretory gland support: 3.9;Spermatogenic cell types: 11.8" "Cell type enhanced" "Detected in some" "medium spiny neuron: 3.9;miscellaneous: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 2.7" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2552 "fallopian tube: 255162.6" "HPA054641, HPA065897" Supported Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 35 Nucleoplasm "Nuclear speckles, Cytosol" "HPA054641: , HPA065897: " "unprognostic (4.06e-1)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (2.47e-3)" TEX15 CT42 ENSG00000133863 "Testis expressed 15, meiosis and synapsis associated" Q9BXT5 8 30831544-30913008 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, DNA damage, DNA repair, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "endometrium 1: 6.3;smooth muscle: 4.9;testis: 11.3" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 179.1;Early primary spermatocytes: 420.2;Early spermatids: 125.5;Ependymal cells: 88.7;Lactotrophs: 44.9;Late primary spermatocytes: 124.6;Late spermatids: 69.4;Undifferentiated spermatogonia: 141.8" "Cell type enriched" "Detected in some" 4 "Spermatogenic cell types: 420.2" "Cell type enhanced" "Detected in many" "ependymal cell: 85.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Skin - Hair cortex cells, Skin - Inner root sheath cells, Testis - Spermatocytes" "Region enhanced" "Detected in single" "olfactory bulb: 2.2" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA036800 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 3: Early primary spermatocytes - Early meiosis" 1 "Nucleoplasm, Cytosol" "HPA036800: " "unprognostic (7.57e-2)" TEX52 ENSG00000283297 "Testis expressed 52" A6NCN8 12 2849046-2857039 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 7.9" "Group enriched" "Detected in some" 18 "Early spermatids: 192.8;Late spermatids: 269.4" "Cell type enriched" "Detected in many" 21 "Spermatogenic cell types: 269.4" "Cell type enhanced" "Detected in some" "choroid plexus epithelial cell: 3.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 1.1" "Lineage enriched" "Detected in single" 7 "NK-cells: 1.1" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA043581 Approved Nucleoplasm,Cytosol NA NA "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 56: Non-specific - Sensory perception" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" Nucleoplasm Cytosol "HPA043581: " "unprognostic (1.72e-1)" "unprognostic (1.29e-1)" "unprognostic (1.24e-1)" TEX9 ENSG00000151575 "Testis expressed 9" Q8N6V9 15 56243971-56445997 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 256.1;Endometrial ciliated cells: 218.5;Ependymal cells: 465.1;Epididymal efferent duct ciliated cells: 197.7;Fallopian tube ciliated cells: 287.6;Lactotrophs: 193.8;Respiratory ciliated cells: 344.8" "Cell type enhanced" "Detected in many" "Ciliated cells: 465.1" "Cell type enhanced" "Detected in all" "ependymal cell: 500.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory B-cell: 10.0;naive B-cell: 8.5" "Lineage enriched" "Detected in many" 5 "B-cells: 10.0" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Skeletal muscle - Fibroblasts, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 773 "Fallopian tube cells: 77273.3" "Tissue enriched" "Detected in single" 73 "fallopian tube: 7301.3" "HPA039415, HPA042036" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Vesicles,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 32: Basophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" 14 "Primary cilium, Centrosome, Cytosol" "Nucleoplasm, Nucleoli fibrillar center, Vesicles, Basal body" "HPA039415: , HPA042036: " "unprognostic (2.81e-1)" "unprognostic (1.08e-1)" "unprognostic (1.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.24e-1)" "unprognostic (5.00e-2)" "unprognostic (2.21e-1)" "unprognostic (2.18e-1)" "unprognostic (9.42e-2)" "unprognostic (1.21e-3)" "potential prognostic favorable (1.05e-6)" "unprognostic (2.61e-3)" "unprognostic (4.91e-2)" "unprognostic (4.28e-1)" "unprognostic (5.79e-2)" "unprognostic (6.87e-2)" "unprognostic (2.14e-1)" "unprognostic (9.62e-2)" "unprognostic (1.11e-1)" "unprognostic (4.40e-2)" "unprognostic (2.41e-2)" "unprognostic (1.69e-1)" "unprognostic (4.30e-2)" "unprognostic (1.22e-2)" "unprognostic (4.02e-1)" "unprognostic (2.58e-2)" "unprognostic (2.28e-1)" "unprognostic (6.78e-2)" "unprognostic (3.38e-2)" "unprognostic (1.66e-1)" TFAP2A "AP-2, AP-2alpha, AP2TF, TFAP2" ENSG00000137203 "Transcription factor AP-2 alpha" P05549 6 10393186-10419659 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 30.8;skin 1: 63.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 133.4;Breast hormone-responsive cells: 158.2;Cytotrophoblasts: 344.5;Extravillous trophoblasts: 368.5;Melanocytes: 387.8;Migrating cytotrophoblasts: 324.0;Retinal amacrine cells: 175.7;Syncytiotrophoblasts: 884.2" "Cell type enhanced" "Detected in many" "Pigment cells: 387.8;Trophoblast cells: 884.2" "Cell type enriched" "Detected in some" 6 "cerebellar inhibitory: 69.0" "Cancer enhanced" "Detected in many" "Skin Cutaneous Melanoma (TCGA): 159.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Group enriched" "Detected in some" 4 "cerebellum: 3.9;pons and medulla: 1.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Collecting ducts: 4952170.6;Keratinocytes: 11288783.1" "Not detected" "Not detected" "CAB000326, HPA056871" Enhanced Enhanced Nucleoplasm NA NA "Cluster 37: Skin - Keratinization" "Cluster 25: Non-specific - Transcription" "Cluster 69: Skin cancer - ECM organization" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 40 Nucleoplasm "CAB000326: , HPA056871: " "unprognostic (8.18e-3)" "unprognostic (7.69e-2)" "unprognostic (4.31e-2)" "unprognostic (1.16e-2)" "unprognostic (5.60e-2)" "unprognostic (2.05e-1)" "unprognostic (3.86e-2)" "unprognostic (1.96e-1)" "unprognostic (2.22e-1)" "unprognostic (2.03e-2)" "validated prognostic unfavorable (1.37e-7)" "validated prognostic unfavorable (4.49e-5)" "potential prognostic unfavorable (3.51e-5)" "potential prognostic unfavorable (9.37e-7)" "unprognostic (4.03e-2)" "potential prognostic unfavorable (2.33e-6)" "unprognostic (7.41e-3)" "unprognostic (7.42e-2)" "unprognostic (2.34e-1)" "unprognostic (1.82e-2)" "unprognostic (1.14e-1)" "unprognostic (4.14e-3)" "unprognostic (1.25e-2)" "unprognostic (1.43e-1)" "unprognostic (9.73e-2)" "unprognostic (4.87e-2)" "unprognostic (1.26e-1)" "unprognostic (1.68e-2)" "unprognostic (2.07e-1)" "unprognostic (9.86e-2)" TFAP2C "AP2-GAMMA, ERF1, hAP-2g, TFAP2G" ENSG00000087510 "Transcription factor AP-2 gamma" Q92754 20 56629306-56639283 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.5;skin 1: 50.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 127.9;Breast myoepithelial cells: 149.0;Breast secretory cells: 106.3;Cytotrophoblasts: 116.2;Esophageal apical cells: 72.7;Extravillous trophoblasts: 105.5;Migrating cytotrophoblasts: 124.6;Salivary myoepithelial cells: 83.3;Suprabasal keratinocytes: 116.8;Syncytiotrophoblasts: 129.3;Tuft cells: 80.7" "Cell type enhanced" "Detected in many" "Basal cells: 127.9;Secretory cells: 106.3;Secretory gland support: 149.0;Suprabasal cells: 116.8;Trophoblast cells: 129.3" "Group enriched" "Detected in some" 4 "astrocyte: 3.4;endothelial cell: 6.0;fibroblast: 12.7" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 83.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 77.7" "Adipose visceral - Mesothelial cells, Lung - Alveolar cells type 2, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Region enriched" "Detected in single" 13 "olfactory bulb: 2.4" "Region enhanced" "Detected in single" "olfactory bulb: 2.5" "Group enriched" "Detected in some" 2441 "Keratinocytes: 194054.5;Large ducts: 294096.7" "Not detected" "Not detected" "CAB016061, CAB016079, HPA055179, HPA057076" Enhanced Supported Nucleoplasm Yes NA "Cluster 58: Skin - Keratinization" "Cluster 51: Neurons - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 9 Nucleoplasm "CAB016061: , CAB016079: , HPA055179: , HPA057076: " "unprognostic (2.68e-1)" "unprognostic (5.45e-2)" "unprognostic (2.23e-1)" "unprognostic (3.94e-2)" "unprognostic (7.30e-2)" "unprognostic (9.58e-2)" "unprognostic (8.69e-3)" "unprognostic (4.61e-2)" "unprognostic (8.74e-2)" "unprognostic (9.65e-2)" "unprognostic (1.54e-1)" "unprognostic (4.23e-2)" "unprognostic (8.32e-3)" "unprognostic (1.98e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-1)" "unprognostic (2.12e-3)" "unprognostic (4.91e-2)" "unprognostic (1.39e-1)" "unprognostic (4.33e-1)" "unprognostic (6.62e-2)" "unprognostic (1.08e-1)" "unprognostic (3.96e-1)" "unprognostic (5.24e-1)" "unprognostic (1.25e-1)" "unprognostic (9.18e-2)" TFB2M "FLJ22661, FLJ23182, Hkp1" ENSG00000162851 "Transcription factor B2, mitochondrial" Q9H5Q4 1 246540561-246566261 "Essential proteins, Predicted intracellular proteins" "rRNA processing, Transcription, Transcription regulation" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 82.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 5611855.2" "Tissue enhanced" "Detected in many" "lung: 812778.7" "HPA028482, HPA028554, HPA030265" Approved Enhanced Mitochondria NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 76: Non-specific - Metabolism" "Cluster 31: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 17 Mitochondria "HPA028482: , HPA028554: , HPA030265: " "unprognostic (2.83e-1)" "unprognostic (6.64e-3)" "unprognostic (2.02e-1)" "unprognostic (6.44e-2)" "unprognostic (2.24e-2)" "unprognostic (2.41e-2)" "unprognostic (1.25e-1)" "unprognostic (2.68e-1)" "unprognostic (2.55e-1)" "unprognostic (1.78e-2)" "potential prognostic favorable (1.06e-4)" "unprognostic (4.00e-2)" "unprognostic (7.35e-3)" "unprognostic (1.32e-2)" "unprognostic (2.47e-2)" "unprognostic (1.02e-1)" "unprognostic (6.07e-3)" "unprognostic (4.93e-2)" "unprognostic (6.52e-2)" "unprognostic (1.95e-2)" "unprognostic (2.12e-1)" "unprognostic (2.00e-2)" "unprognostic (2.00e-1)" "unprognostic (2.86e-2)" "unprognostic (5.91e-3)" "unprognostic (2.69e-1)" "unprognostic (1.40e-1)" "unprognostic (1.23e-1)" "unprognostic (1.07e-1)" "unprognostic (7.05e-2)" "unprognostic (9.14e-2)" TFCP2L1 "CRTR1, LBP-9" ENSG00000115112 "Transcription factor CP2 like 1" Q9NZI6 2 121216587-121285202 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 46.2;salivary gland: 92.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 568.5;Conjunctival goblet cells: 1196.1;Distal convoluted tubule cells: 669.9;Lacrimal acinar cells: 1463.8;Loop of henle epithelial cells: 585.3;Renal collecting duct intercalated cells: 1735.2;Renal connecting tubule cells: 629.5;Respiratory ionocytes: 1066.8;Salivary basal cells: 1409.5;Salivary duct cells: 2546.6;Salivary ionocytes: 1876.4;Submucosal glandular cells: 720.9" "Cell type enhanced" "Detected in many" "Acinar cells: 1463.8;Basal cells: 1409.5;Ductal cells: 2546.6;Goblet cells: 1196.1;Ionocytes: 1876.4" "Cell type enriched" "Detected in some" 6 "choroid plexus epithelial cell: 207.8" "Group enriched" "Detected in many" 5 "Kidney Chromophobe (TCGA): 93.2;Testicular Germ Cell Tumor (TCGA): 33.6" "Region enriched" "Detected in all" 8 "choroid plexus: 39.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Macrophages, Breast - Breast glandular cells, Colon - Colon enterocytes, Minor Salivary Gland - Minor salivary gland ductal cells, Skin - Eccrine sweat gland cells, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 1623885.1;Large ducts: 5364438.5" "Tissue enriched" "Detected in single" 422 "salivary gland: 42239.3" HPA029708 Uncertain Approved "Nucleoli fibrillar center,Mitochondria" Yes NA "Cluster 72: Kidney - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 1 "Nucleoli fibrillar center" Mitochondria "HPA029708: " "unprognostic (1.08e-1)" "unprognostic (4.27e-2)" "unprognostic (1.31e-1)" "unprognostic (2.15e-1)" "unprognostic (2.75e-1)" "unprognostic (4.98e-2)" "unprognostic (3.25e-1)" "unprognostic (7.35e-3)" "unprognostic (8.53e-2)" "unprognostic (4.18e-2)" "unprognostic (5.55e-2)" "unprognostic (3.22e-1)" "unprognostic (3.05e-1)" "unprognostic (4.68e-2)" "unprognostic (6.00e-2)" "unprognostic (1.22e-1)" "unprognostic (8.24e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-3)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (8.41e-4)" "unprognostic (2.19e-1)" "unprognostic (1.91e-1)" "unprognostic (2.73e-1)" "unprognostic (8.34e-2)" "unprognostic (1.02e-1)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (1.00e-2)" "unprognostic (1.14e-2)" TFDP2 Dp-2 ENSG00000114126 "Transcription factor Dp-2" Q14188 3 141944428-142149544 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 157.9" "Cell type enhanced" "Detected in all" "Early spermatids: 1042.2;Late primary spermatocytes: 801.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1042.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 691 "Collecting ducts: 41830.3;Distal tubules: 122594.9;Granulosa cells: 42966.0" "Tissue enriched" "Detected in single" 51 "kidney: 5107.8" "CAB018396, HPA070399" Supported Supported "Nucleoplasm,Vesicles,Mitotic spindle" Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 80: Thymus - Adaptive immune response" "Cluster 25: Non-specific - Transcription" "Cluster 59: Leukemia - T-cell receptor" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 17 Nucleoplasm "Vesicles, Mitotic spindle" "CAB018396: , HPA070399: " "unprognostic (3.17e-1)" "unprognostic (1.53e-2)" "unprognostic (3.59e-1)" "unprognostic (4.44e-2)" "unprognostic (1.49e-1)" "unprognostic (2.88e-1)" "unprognostic (1.81e-2)" "potential prognostic favorable (5.07e-4)" "unprognostic (1.65e-1)" "unprognostic (4.28e-3)" "unprognostic (7.58e-3)" "unprognostic (3.53e-3)" "unprognostic (1.77e-1)" "validated prognostic unfavorable (8.44e-6)" "validated prognostic unfavorable (5.85e-4)" "unprognostic (3.62e-1)" "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.53e-1)" "unprognostic (7.64e-2)" "unprognostic (3.21e-3)" "unprognostic (1.63e-3)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "potential prognostic favorable (1.93e-4)" "unprognostic (1.03e-1)" "unprognostic (8.22e-2)" "unprognostic (1.39e-1)" "unprognostic (3.49e-1)" "unprognostic (2.58e-1)" "unprognostic (1.65e-1)" TFEC "bHLHe34, TCFEC, TFECL" ENSG00000105967 "Transcription factor EC" O14948 7 115935148-116159896 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.2;kidney: 19.1;lymphoid tissue: 20.6" "Cell type enhanced" "Detected in many" "B-cells: 130.0;cDC: 93.8;Hematopoietic stem cells: 165.9;Hofbauer cells: 86.7;Kupffer cells: 152.7;Macrophages: 218.1;Megakaryocyte progenitors: 86.1;Microglia: 237.4;Monocyte progenitors: 204.7;monocytes: 176.8;Neutrophil progenitors: 81.4;pDCs: 115.6;Proximal tubule cells: 84.0" "Cell type enhanced" "Detected in many" "B-cells: 130.0;dendritic cells: 115.6;Glial cells: 237.4;Mononuclear phagocytes: 218.1;Stem cells: 165.9" "Cell type enriched" "Detected in some" 13 "central nervous system macrophage: 315.3" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 15.1" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 7.1;intermediate monocyte: 2.8;memory B-cell: 3.8;myeloid DC: 6.3;naive B-cell: 2.5;plasmacytoid DC: 3.3" "Group enriched" "Detected in many" 29 "B-cells: 3.8;dendritic cells: 6.3;monocytes: 7.1" "Group enriched" "Detected in some" 13 "Leukemia: 12.5;lymphoma: 21.4;Rhabdoid: 6.6" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Adrenal gland - Macrophages, Breast - Macrophages, Colon - Macrophages, Heart muscle - Macrophages, Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Liver - Kupffer cells, Lung - Macrophages, Minor Salivary Gland - Macrophages, Pancreas - Macrophages, Prostate - Macrophages, Skeletal muscle - Macrophages, Stomach - Macrophages" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 15900 "Macrophages: 1589968.0" "Not detected" "Not detected" "CAB032260, HPA050528, HPA063577" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 55: Lymphoma - Immune response" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 3 Nucleoplasm Cytosol "CAB032260: , HPA050528: , HPA063577: " "unprognostic (2.57e-1)" "unprognostic (1.01e-1)" "unprognostic (1.90e-2)" "unprognostic (9.86e-3)" "unprognostic (6.54e-2)" "unprognostic (1.62e-1)" "unprognostic (7.37e-2)" "unprognostic (1.82e-1)" "unprognostic (4.71e-2)" "potential prognostic favorable (1.89e-7)" "unprognostic (7.76e-3)" "unprognostic (7.05e-3)" "unprognostic (1.32e-1)" "unprognostic (9.83e-3)" "unprognostic (5.99e-2)" "unprognostic (1.09e-1)" "unprognostic (4.23e-1)" "unprognostic (1.34e-1)" "unprognostic (8.23e-2)" "unprognostic (3.18e-1)" "unprognostic (1.68e-2)" "unprognostic (8.69e-3)" "unprognostic (3.01e-1)" "unprognostic (2.33e-2)" "unprognostic (1.74e-1)" TFF3 "HITF, ITF" ENSG00000160180 "Trefoil factor 3" Q07654 21 42311667-42315409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 434.3;intestine: 509.9;salivary gland: 533.9;thyroid gland: 558.7" "Cell type enriched" "Detected in many" 19 "Goblet cells: 56753.5" "Cell type enriched" "Detected in many" 19 "Goblet cells: 56753.5" "Group enriched" "Detected in some" 7 "ependymal cell: 1.6;fibroblast: 4.4;pericyte: 1.1" "Cancer enhanced" "Detected in all" "Colon Adenocarcinoma (TCGA): 717.7" "Region enriched" "Detected in single" 6 "midbrain: 4.6" "Immune cell enriched" "Detected in single" 16 "eosinophil: 1.6" "Lineage enriched" "Detected in single" 16 "granulocytes: 1.6" "Cancer enhanced" "Detected in many" "breast cancer: 357.7;colorectal cancer: 184.6" "Adipose subcutaneous - Smooth muscle cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skeletal muscle - Smooth muscle cells" "Region enriched" "Detected in single" 15 "cerebellum: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB020681, HPA035464" Enhanced Approved Nucleoplasm,Nucleoli "Secreted to blood" "No annotated function" No NA 151000000 4200000 "Cluster 77: Intestine - Digestion" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 70: Intestinal goblet cells - Mucin production" 5 Nucleoplasm Nucleoli "CAB020681: , HPA035464: " "unprognostic (1.55e-1)" "unprognostic (7.58e-2)" "unprognostic (1.85e-2)" "unprognostic (4.83e-3)" "unprognostic (4.19e-2)" "unprognostic (2.51e-2)" "unprognostic (2.20e-2)" "unprognostic (6.03e-2)" "unprognostic (3.60e-1)" "unprognostic (4.56e-2)" "potential prognostic favorable (2.11e-5)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (9.38e-4)" "unprognostic (6.18e-2)" "unprognostic (2.98e-1)" "unprognostic (2.10e-1)" "unprognostic (3.35e-1)" "unprognostic (9.04e-2)" "unprognostic (3.66e-2)" "unprognostic (3.68e-1)" "unprognostic (1.42e-3)" "unprognostic (7.28e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (4.36e-5)" "unprognostic (1.61e-1)" "unprognostic (2.77e-1)" "unprognostic (2.45e-1)" "unprognostic (1.61e-2)" "unprognostic (7.17e-3)" TFG "FLJ36137, SPG57, TF6" ENSG00000114354 "Trafficking from ER to golgi regulator" Q92734 3 100709295-100748964 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Transport" "Cancer-related genes, Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 402.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic islets: 38245728.3" "Low tissue specificity" "Detected in all" "HPA019473, HPA052206" Approved Approved Vesicles,Cytosol No No 170000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 76: Non-specific - Metabolism" "Cluster 21: Non-specific - Metabolism" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 63 Vesicles Cytosol "HPA019473: , HPA052206: " "unprognostic (3.97e-1)" "unprognostic (1.49e-2)" "unprognostic (1.05e-1)" "unprognostic (8.89e-2)" "unprognostic (2.56e-1)" "unprognostic (1.91e-1)" "unprognostic (2.26e-1)" "unprognostic (7.55e-2)" "unprognostic (1.22e-2)" "unprognostic (6.85e-3)" "unprognostic (1.04e-2)" "potential prognostic unfavorable (7.60e-7)" "unprognostic (3.11e-1)" "potential prognostic unfavorable (2.60e-6)" "unprognostic (2.24e-2)" "unprognostic (1.42e-3)" "unprognostic (6.17e-3)" "unprognostic (1.52e-1)" "unprognostic (4.32e-2)" "unprognostic (1.84e-1)" "unprognostic (7.92e-2)" "potential prognostic unfavorable (5.06e-4)" "unprognostic (1.38e-2)" "unprognostic (2.57e-2)" "unprognostic (1.77e-2)" "unprognostic (1.68e-1)" "unprognostic (1.77e-1)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (2.28e-1)" "unprognostic (2.63e-1)" TFR2 "HFE3, TFRC2" ENSG00000106327 "Transferrin receptor 2" Q9UP52 7 100620416-100642779 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Transporters" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "liver: 313.5" "Cell type enhanced" "Detected in many" "Early spermatids: 68.0;Erythrocyte progenitors: 236.0;Hepatocytes: 531.0;Megakaryocyte progenitors: 40.9;Megakaryocyte-Erythroid progenitors: 125.9;Parietal cells: 47.7" "Cell type enhanced" "Detected in many" "Erythrocytes: 236.0;Hepatocytes: 531.0;Megakaryocytes: 125.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in some" 164 "Liver Hepatocellular Carcinoma (TCGA): 184.1" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 23 "basophil: 2.5;eosinophil: 1.9" "Lineage enriched" "Detected in single" 26 "granulocytes: 2.5" "Cancer enriched" "Detected in some" 7 "Leukemia: 23.6" "Liver - Hepatocytes, Spleen - Erythrocytes, Stomach - Parietal cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" 2 "Hepatocytes: 17231811.9" "Tissue enriched" "Detected in single" 128532 "liver: 12853178.9" "CAB016255, HPA017171, HPA073125" Enhanced Approved "Golgi apparatus" NA NA 1400000 "Cluster 46: Basophils - Proteolysis" "Cluster 53: Liver - Plasma proteins" "Cluster 15: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 25: Hepatocytes - Plasma protein synthesis & secretion" 4 "Golgi apparatus" "CAB016255: , HPA017171: , HPA073125: " "unprognostic (1.14e-2)" "unprognostic (4.07e-2)" "unprognostic (2.15e-2)" "unprognostic (4.51e-3)" "unprognostic (1.07e-1)" "unprognostic (3.31e-2)" "unprognostic (4.06e-2)" TGDS "SDR2E1, TDPGD" ENSG00000088451 "TDP-glucose 4,6-dehydratase" O95455 13 94574054-94596242 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039927, HPA040857" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA No "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 19: Non-specific - Unknown function" "Cluster 67: Plasma cells - Plasma cell differentiation" 2 Nucleoplasm "Nucleoli, Cytosol" "HPA039927: , HPA040857: " "unprognostic (1.74e-1)" "unprognostic (6.74e-2)" "unprognostic (3.00e-1)" "unprognostic (1.62e-1)" "unprognostic (3.93e-2)" "unprognostic (2.82e-1)" "unprognostic (2.12e-1)" "unprognostic (2.43e-1)" "unprognostic (4.98e-2)" "unprognostic (1.88e-1)" "potential prognostic favorable (6.58e-5)" "unprognostic (1.85e-2)" "unprognostic (4.23e-2)" "unprognostic (2.44e-1)" "unprognostic (6.99e-2)" "unprognostic (2.19e-1)" "unprognostic (6.22e-3)" "unprognostic (2.30e-1)" "unprognostic (9.32e-2)" "unprognostic (2.57e-1)" "unprognostic (1.80e-1)" "unprognostic (6.44e-2)" "unprognostic (8.28e-3)" "potential prognostic unfavorable (6.32e-5)" "unprognostic (1.36e-2)" "unprognostic (2.66e-1)" "unprognostic (3.75e-2)" "unprognostic (3.28e-2)" "unprognostic (9.41e-2)" "unprognostic (2.53e-1)" "unprognostic (1.42e-1)" TGFA ENSG00000163235 "Transforming growth factor alpha" P01135 2 70447284-70554193 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Growth factor, Mitogen" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.5;esophagus: 24.0" "Cell type enhanced" "Detected in many" "Early spermatids: 145.7;Endometrial glandular cells: 116.4;Esophageal apical cells: 305.9;Neutrophils: 146.0;Pancreatic duct cells: 150.7;Urothelial cells: 180.9" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 305.9;Barrier epithelial cells: 180.9" "Cell type enhanced" "Detected in many" "oligodendrocyte: 56.1;oligodendrocyte precursor cell: 137.0" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 62.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 11.4;eosinophil: 23.9;neutrophil: 24.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 24.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 179.0" "Spleen - Macrophages, Stomach - Gastric mucous cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA042297 Approved Approved Vesicles "Secreted to blood" "Growth factor" No No 57900 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 24: Neutrophils - Innate immunity signal integration" 10 Vesicles "HPA042297: " "unprognostic (7.92e-2)" "unprognostic (1.04e-1)" "unprognostic (1.63e-1)" "unprognostic (1.77e-3)" "unprognostic (5.90e-2)" "unprognostic (3.55e-2)" "unprognostic (1.69e-1)" "unprognostic (1.11e-1)" "unprognostic (1.05e-2)" "unprognostic (9.47e-2)" "validated prognostic favorable (5.79e-10)" "validated prognostic favorable (6.64e-5)" "unprognostic (1.54e-1)" "unprognostic (1.31e-1)" "unprognostic (1.79e-1)" "unprognostic (8.19e-3)" "unprognostic (1.58e-2)" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (6.84e-2)" "unprognostic (5.11e-2)" "potential prognostic unfavorable (2.31e-5)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (9.22e-2)" "unprognostic (7.00e-2)" "unprognostic (2.36e-2)" "unprognostic (7.47e-2)" "unprognostic (1.91e-1)" "unprognostic (1.00e-3)" "unprognostic (3.05e-1)" TGFB1 "CED, DPD1, TGFB, TGFbeta" ENSG00000105329 "Transforming growth factor beta 1" 19 41301587-41353922 "Human disease related genes, Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 828.5;Innate lymphoid cells: 436.8;Megakaryocyte progenitors: 421.2;Megakaryocytes: 822.2;Neutrophils: 497.6;NK-cells: 520.5;pDCs: 484.2;Platelets: 2842.4;T-cells: 460.1" "Cell type enhanced" "Detected in all" "Megakaryocytes: 822.2;Platelets: 2842.4;Trophoblast cells: 828.5" "Group enriched" "Detected in all" 4 "central nervous system macrophage: 197.4;leukocyte: 225.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.9" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000361, HPA073356" Approved Approved "Golgi apparatus,Plasma membrane,Basal body" "Secreted to blood" NA NA 1290000 "Cluster 45: Eosinophils - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 43: Hindbrain - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 20: Non-specific - Transcription regulation" 16 "Golgi apparatus, Plasma membrane" "Basal body" "CAB000361: , HPA073356: " "unprognostic (3.13e-2)" "unprognostic (4.28e-2)" "unprognostic (2.82e-1)" "unprognostic (1.98e-3)" "unprognostic (6.77e-3)" "unprognostic (1.62e-1)" "unprognostic (3.33e-2)" "unprognostic (4.14e-3)" "unprognostic (1.81e-3)" "unprognostic (2.75e-1)" "unprognostic (3.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.43e-3)" "unprognostic (1.23e-2)" "unprognostic (6.86e-2)" "unprognostic (4.84e-2)" "unprognostic (5.55e-3)" "unprognostic (3.78e-2)" "unprognostic (2.18e-2)" "unprognostic (1.70e-2)" "unprognostic (3.15e-1)" "unprognostic (1.04e-1)" "unprognostic (2.20e-2)" "unprognostic (3.02e-1)" "unprognostic (8.80e-2)" "unprognostic (4.49e-2)" "unprognostic (1.38e-2)" "unprognostic (9.53e-3)" "unprognostic (1.07e-2)" "unprognostic (9.84e-3)" "unprognostic (2.50e-2)" TGFB1I1 "ARA55, Hic-5, TSC-5" ENSG00000140682 "Transforming growth factor beta 1 induced transcript 1" O43294 16 31471585-31477960 "Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 258.0;intestine: 251.1" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 279.9;Decidual stromal cells: 330.7;Hepatic stellate cells: 200.1;Megakaryocytes: 593.4;Ovarian stromal cells: 111.6;Pericytes: 144.9;Peritubular myoid cells: 160.6;Platelets: 211.1;Salivary myoepithelial cells: 95.0;Smooth muscle cells: 438.8;Vascular smooth muscle cells: 202.4" "Cell type enhanced" "Detected in many" "Megakaryocytes: 593.4;Platelets: 211.1;Secretory gland support: 279.9;Smooth muscle cells: 438.8;Stromal cells: 330.7" "Group enriched" "Detected in some" 5 "pericyte: 69.6;vascular associated smooth muscle cell: 100.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "basophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Smooth muscle cells, Colon - Smooth muscle cells, Lung - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 209400942.8" "Tissue enhanced" "Detected in all" "blood vessel: 41154471.4;Stomach: 40461453.7" "CAB020844, HPA072360" Enhanced Supported "Vesicles,Focal adhesion sites,Cytosol" NA NA 280000 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 47: Endothelial cells - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 62: Smooth muscle cells - Muscle contraction" 17 "Focal adhesion sites" "Vesicles, Cytosol" "CAB020844: , HPA072360: " "unprognostic (3.90e-1)" "unprognostic (6.92e-2)" "unprognostic (8.06e-2)" "unprognostic (2.15e-2)" "unprognostic (3.52e-2)" "unprognostic (2.20e-2)" "unprognostic (1.30e-1)" "unprognostic (4.98e-2)" "unprognostic (1.51e-1)" "unprognostic (7.73e-2)" "unprognostic (2.09e-2)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (2.23e-1)" "unprognostic (3.46e-2)" "unprognostic (1.67e-2)" "unprognostic (7.28e-3)" "unprognostic (2.82e-2)" "unprognostic (1.14e-1)" "potential prognostic unfavorable (4.86e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-1)" "unprognostic (4.55e-2)" "unprognostic (6.69e-2)" "unprognostic (2.96e-2)" "unprognostic (2.51e-2)" "unprognostic (9.97e-2)" "unprognostic (4.27e-3)" "unprognostic (2.52e-1)" "unprognostic (2.04e-1)" "unprognostic (6.42e-2)" TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 446.4;Choroid plexus epithelial cells: 582.0;Lymphatic endothelial cells: 890.2;Microglia: 559.4;Neutrophils: 767.3;pDCs: 462.8;Vascular endothelial cells: 805.9" "Cell type enhanced" "Detected in all" "Endothelial cells: 890.2;Neutrophils: 767.3" "Group enriched" "Detected in many" 9 "central nervous system macrophage: 646.8;choroid plexus epithelial cell: 610.3;endothelial cell: 572.4;fibroblast: 371.1;leukocyte: 407.5;pericyte: 296.7;vascular associated smooth muscle cell: 163.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Kidney - Endothelial cells, Pancreas - Endothelial cells, Pituitary gland - Endothelial cells, Stomach - Endothelial cells, Testis - Endothelial cells, Thyroid gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Alveolar cell types: 1668045.3;Glomeruli: 2396242.7" "Tissue enhanced" "Detected in many" "intestine: 1230588.4" "CAB073537, HPA074821" Enhanced "Plasma membrane" "Secreted to blood" Receptor NA NA 550000 "Cluster 20: Non-specific - DNA binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 94 "Plasma membrane" "CAB073537: , HPA074821: " "unprognostic (1.13e-1)" "unprognostic (4.37e-1)" "unprognostic (4.60e-2)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (1.72e-1)" "unprognostic (1.67e-1)" "unprognostic (2.78e-2)" "unprognostic (2.10e-1)" "unprognostic (2.92e-3)" "validated prognostic favorable (2.35e-7)" "validated prognostic favorable (3.61e-4)" "unprognostic (2.97e-1)" "unprognostic (2.96e-1)" "unprognostic (3.33e-2)" "unprognostic (8.78e-2)" "unprognostic (2.21e-1)" "unprognostic (4.04e-2)" "unprognostic (5.62e-2)" "unprognostic (5.82e-3)" "unprognostic (1.32e-3)" "unprognostic (3.90e-2)" "unprognostic (6.15e-2)" "unprognostic (1.91e-1)" "unprognostic (2.00e-1)" "unprognostic (2.75e-3)" "unprognostic (2.56e-1)" "unprognostic (4.84e-2)" "unprognostic (1.94e-2)" "unprognostic (3.62e-2)" "unprognostic (1.88e-1)" TGIF2LX ENSG00000153779 "TGFB induced factor homeobox 2 like X-linked" Q8IUE1 X 89921908-89922883 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 86 "testis: 8.6" "Group enriched" "Detected in some" 51 "Early spermatids: 61.5;Late primary spermatocytes: 49.4;Late spermatids: 62.6" "Cell type enriched" "Detected in some" 56 "Spermatogenic cell types: 62.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Myeloma: 3.1;Neuroblastoma: 3.6" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA034543 Supported Approved Nucleoplasm No No "Cluster 6: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 22 Nucleoplasm "HPA034543: " TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "blood vessel: 775.7" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 399.8;Decidual stromal cells: 1215.0;Endometrial secretory cells: 221.7;Endometrial stromal cells: 343.4;Epididymal efferent duct absorptive cells: 825.2;Lymphatic endothelial cells: 298.5;Migrating cytotrophoblasts: 293.4;Syncytiotrophoblasts: 453.5;Vascular endothelial cells: 243.8;Vascular smooth muscle cells: 285.8" "Cell type enhanced" "Detected in many" "Ductal cells: 825.2;Stromal cells: 1215.0;Trophoblast cells: 453.5" "Cell type enriched" "Detected in some" 4 "endothelial cell: 270.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "pancreatic cancer: 424.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 443947057.4;Smooth muscle cells: 576347666.4" "Low tissue specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Enzyme Yes No 970000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 25 Cytosol "Plasma membrane" "CAB002598: , HPA021019: , HPA029518: " "unprognostic (6.82e-2)" "unprognostic (2.33e-1)" "unprognostic (5.50e-2)" "unprognostic (6.11e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-1)" "unprognostic (1.23e-3)" "potential prognostic unfavorable (1.34e-5)" "unprognostic (2.27e-3)" "unprognostic (2.64e-1)" "unprognostic (1.80e-2)" "unprognostic (1.00e-1)" "unprognostic (5.00e-2)" "unprognostic (2.13e-1)" "unprognostic (2.50e-1)" "unprognostic (1.21e-1)" "unprognostic (1.20e-1)" "unprognostic (1.55e-3)" "unprognostic (3.78e-3)" "unprognostic (9.74e-3)" "potential prognostic unfavorable (3.77e-4)" "unprognostic (3.06e-3)" "potential prognostic unfavorable (6.14e-5)" "unprognostic (7.61e-2)" "unprognostic (4.89e-2)" "unprognostic (1.41e-2)" "unprognostic (2.35e-1)" "unprognostic (4.98e-3)" "unprognostic (2.75e-3)" "unprognostic (2.77e-1)" "unprognostic (3.45e-1)" THAP1 "4833431A01Rik, DYT6, FLJ10477" ENSG00000131931 "THAP domain containing 1" Q9NVV9 8 42836674-42843325 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" DNA-binding "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 48.2;Oocytes: 50.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 556 "lymphoid tissue: 55565.9" HPA071310 Supported Nucleoplasm No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 9: T-cells - Adaptive immunity: Regulation" 93 Nucleoplasm "HPA071310: " "unprognostic (2.69e-1)" "unprognostic (1.31e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-3)" "unprognostic (5.58e-2)" "unprognostic (1.30e-1)" "unprognostic (4.04e-2)" "unprognostic (1.09e-1)" "unprognostic (5.43e-2)" "unprognostic (4.78e-3)" "potential prognostic favorable (2.22e-8)" "unprognostic (7.61e-3)" "unprognostic (5.91e-2)" "unprognostic (6.67e-2)" "unprognostic (1.60e-1)" "unprognostic (1.81e-1)" "unprognostic (1.97e-1)" "unprognostic (7.40e-2)" "unprognostic (3.01e-2)" "unprognostic (5.35e-2)" "unprognostic (2.68e-3)" "unprognostic (2.97e-2)" "unprognostic (2.06e-2)" "unprognostic (5.23e-2)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (1.89e-2)" "unprognostic (1.46e-1)" "unprognostic (4.23e-1)" "unprognostic (2.22e-1)" "unprognostic (1.18e-2)" THAP10 ENSG00000129028 "THAP domain containing 10" Q9P2Z0 15 70881342-70892433 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epicardial cells: 29.6;Late primary spermatocytes: 27.4;Oocytes: 32.2;Parietal cells: 46.0;Retinal bipolar cells: 15.4" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 29.6;Gastric glandular cells: 46.0;Oocytes: 32.2;Spermatogenic cell types: 27.4" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 15.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "non-classical monocyte: 4.2" "Lineage enriched" "Detected in single" 7 "monocytes: 4.2" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041416, HPA073220" Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 16: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 21 Nucleoplasm "Golgi apparatus, Cytosol" "HPA041416: , HPA073220: " "unprognostic (1.37e-2)" "unprognostic (4.08e-2)" "unprognostic (6.42e-2)" "unprognostic (1.03e-1)" "unprognostic (3.87e-2)" "unprognostic (5.62e-2)" "unprognostic (1.26e-1)" "unprognostic (1.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.51e-2)" "potential prognostic favorable (1.03e-8)" "unprognostic (1.69e-2)" "unprognostic (2.71e-3)" "unprognostic (2.27e-1)" "unprognostic (1.89e-1)" "unprognostic (1.51e-3)" "unprognostic (1.43e-1)" "unprognostic (4.19e-2)" "unprognostic (2.43e-1)" "unprognostic (1.93e-2)" "unprognostic (1.74e-1)" "unprognostic (1.10e-1)" "unprognostic (3.58e-1)" "unprognostic (1.76e-3)" "unprognostic (1.50e-2)" "unprognostic (2.94e-2)" "unprognostic (1.73e-2)" "unprognostic (1.38e-1)" "unprognostic (2.58e-1)" "unprognostic (6.31e-2)" "unprognostic (1.01e-2)" THAP11 "CTG-B43a, CTG-B45d, HRIHFB2206, RONIN" ENSG00000168286 "THAP domain containing 11" Q96EK4 16 67842320-67844195 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Epilepsy, Intellectual disability, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 53.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 2280272.7" "Group enriched" "Detected in many" "fallopian tube: 301315.8;lymphoid tissue: 602524.9" "HPA041434, HPA042189, HPA072537" Supported Supported Nucleoplasm,Cytosol NA No "Cluster 33: Non-specific - ATP binding" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 16 Nucleoplasm Cytosol "HPA041434: , HPA042189: , HPA072537: " "unprognostic (2.29e-1)" "unprognostic (2.46e-1)" "unprognostic (1.73e-1)" "unprognostic (2.30e-2)" "unprognostic (1.27e-1)" "unprognostic (7.73e-2)" "unprognostic (2.96e-3)" "unprognostic (3.77e-3)" "unprognostic (1.16e-1)" "unprognostic (6.76e-2)" "potential prognostic favorable (1.10e-4)" "unprognostic (7.50e-2)" "unprognostic (8.37e-2)" "potential prognostic unfavorable (7.60e-4)" "unprognostic (3.61e-3)" "unprognostic (5.42e-2)" "unprognostic (2.36e-2)" "unprognostic (1.17e-1)" "unprognostic (8.35e-3)" "unprognostic (1.90e-1)" "unprognostic (2.49e-1)" "unprognostic (1.13e-1)" "unprognostic (9.45e-2)" "unprognostic (2.43e-1)" "unprognostic (6.53e-2)" "unprognostic (1.67e-1)" "unprognostic (6.77e-2)" "unprognostic (3.25e-1)" "unprognostic (6.80e-2)" "unprognostic (5.09e-3)" "unprognostic (5.93e-2)" THAP3 ENSG00000041988 "THAP domain containing 3" Q8WTV1 1 6624868-6635586 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 1634 "lymphoid tissue: 163440.3" HPA067114 Approved Approved Nucleoplasm,Nucleoli,Mitochondria No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 110: Mural cells - ECM organization" 18 Nucleoplasm "Nucleoli, Mitochondria" "HPA067114: " "unprognostic (3.52e-1)" "unprognostic (2.03e-1)" "unprognostic (4.49e-2)" "unprognostic (7.33e-2)" "unprognostic (3.80e-2)" "unprognostic (6.19e-3)" "unprognostic (2.53e-1)" "unprognostic (1.00e-2)" "unprognostic (5.38e-2)" "unprognostic (1.26e-1)" "unprognostic (1.06e-1)" "unprognostic (2.64e-3)" "unprognostic (6.23e-3)" "potential prognostic unfavorable (7.90e-5)" "unprognostic (1.38e-3)" "unprognostic (1.85e-2)" "unprognostic (1.14e-1)" "unprognostic (1.81e-2)" "unprognostic (1.97e-1)" "unprognostic (1.40e-1)" "unprognostic (6.72e-2)" "unprognostic (5.16e-3)" "unprognostic (6.10e-2)" "unprognostic (1.74e-1)" "unprognostic (4.18e-2)" "unprognostic (4.50e-3)" "unprognostic (3.87e-1)" "unprognostic (1.37e-1)" "unprognostic (3.69e-2)" "unprognostic (2.47e-1)" "unprognostic (1.45e-1)" THAP4 "CGI-36, Nb(III)" ENSG00000176946 "THAP domain containing 4" Q8WY91 2 241584405-241637158 "Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "DNA-binding, Isomerase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 1472563.1" "Tissue enhanced" "Detected in many" "cerebral cortex: 11076828.2;kidney: 12163730.2" HPA044982 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 52: Non-specific - Cellular respiration" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 39 "Nucleoplasm, Cytosol" "HPA044982: " "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (1.55e-1)" "unprognostic (2.12e-1)" "unprognostic (1.25e-1)" "unprognostic (2.24e-1)" "unprognostic (5.75e-3)" "unprognostic (1.15e-1)" "unprognostic (2.34e-2)" "unprognostic (1.38e-1)" "unprognostic (1.12e-3)" "unprognostic (4.71e-3)" "potential prognostic favorable (2.07e-5)" "unprognostic (5.66e-3)" "potential prognostic unfavorable (5.66e-5)" "unprognostic (2.01e-2)" "unprognostic (6.67e-2)" "unprognostic (1.51e-1)" "unprognostic (4.77e-2)" "unprognostic (2.18e-1)" "unprognostic (7.35e-2)" "unprognostic (1.08e-1)" "unprognostic (1.24e-1)" "unprognostic (4.46e-2)" "unprognostic (3.25e-1)" "unprognostic (2.67e-1)" "unprognostic (1.40e-1)" "unprognostic (1.27e-1)" "unprognostic (5.15e-2)" "unprognostic (2.22e-1)" "unprognostic (1.51e-1)" THAP9 FLJ34093 ENSG00000168152 "THAP domain containing 9" Q9H5L6 4 82900684-82919969 "Predicted intracellular proteins, Transcription factors" "DNA integration, DNA recombination" "DNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 65.5;Late spermatids: 81.2;Neutrophils: 69.3" "Cell type enhanced" "Detected in many" "Neutrophils: 69.3;Spermatogenic cell types: 81.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 927 "Granulosa cells: 92724.1" "Tissue enriched" "Detected in single" 29316 "lymphoid tissue: 2931572.7" "HPA037420, HPA037421" Uncertain Approved Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1 Mitochondria "HPA037420: , HPA037421: " "unprognostic (5.03e-2)" "unprognostic (2.19e-3)" "unprognostic (3.99e-1)" "unprognostic (1.79e-2)" "unprognostic (2.46e-2)" "unprognostic (2.48e-2)" "unprognostic (3.62e-1)" "unprognostic (1.35e-1)" "unprognostic (2.06e-2)" "unprognostic (1.12e-1)" "validated prognostic favorable (3.53e-7)" "validated prognostic favorable (1.43e-4)" "unprognostic (1.90e-2)" "unprognostic (1.87e-1)" "unprognostic (9.78e-3)" "unprognostic (1.28e-1)" "unprognostic (5.62e-2)" "unprognostic (8.77e-2)" "unprognostic (2.10e-2)" "unprognostic (1.18e-1)" "unprognostic (2.62e-1)" "unprognostic (3.47e-2)" "unprognostic (9.62e-2)" "unprognostic (2.32e-2)" "unprognostic (4.05e-3)" "unprognostic (1.04e-1)" "unprognostic (6.60e-2)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (2.03e-2)" "unprognostic (1.53e-1)" THEG "CT56, THEG1" ENSG00000105549 "Theg spermatid protein" Q9P2T0 19 361747-376026 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 40.2" "Cell type enriched" "Detected in some" 6 "Late spermatids: 994.7" "Cell type enriched" "Detected in some" 95 "Spermatogenic cell types: 994.7" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 11.4;prostate cancer: 9.8" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078077 Approved "Cytosol,Equatorial segment,Principal piece,Annulus" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 6 "Cytosol, Equatorial segment, Principal piece, Annulus" "HPA078077: " "unprognostic (2.02e-2)" "unprognostic (1.60e-1)" "unprognostic (2.66e-1)" THNSL1 "FLJ22002, TSH1" ENSG00000185875 "Threonine synthase like 1" Q8IYQ7 10 25016612-25026664 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 20.0" "Cell type enhanced" "Detected in some" "Astrocytes: 6.1;Bergmann glia: 5.4;Brain excitatory neurons: 7.7;Brain inhibitory neurons: 9.0;Choroid plexus epithelial cells: 5.7;Distal convoluted tubule cells: 5.6;Ependymal cells: 6.5;Loop of henle epithelial cells: 5.2;Microglia: 7.6;Oligodendrocyte progenitor cells: 5.9;Oligodendrocytes: 8.2;Other brain neurons: 9.7;Podocytes: 5.2;Proximal tubule cells: 4.9;Renal collecting duct principal cells: 4.6;Renal connecting tubule cells: 3.9" "Cell type enhanced" "Detected in some" "Ciliated cells: 6.5;Ductal cells: 4.6;Glial cells: 8.2;Neuronal cells: 9.7;Renal nephron cells: 5.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 60640547.5" "Tissue enhanced" "Detected in many" "liver: 13458557.3" HPA037585 Uncertain Approved "Nuclear bodies,Mitochondria,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 16: Liver & Kidney - Metabolism" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 98: Neurons - Neurotransmission & signaling" 7 "Nuclear bodies, Cytosol" Mitochondria "HPA037585: " "unprognostic (2.68e-1)" "unprognostic (1.33e-1)" "unprognostic (2.53e-1)" "unprognostic (1.40e-1)" "unprognostic (1.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.55e-1)" "unprognostic (5.32e-3)" "unprognostic (1.40e-1)" "unprognostic (3.05e-3)" "potential prognostic favorable (1.67e-7)" "unprognostic (6.73e-3)" "unprognostic (4.51e-2)" "unprognostic (5.15e-2)" "unprognostic (3.07e-2)" "unprognostic (1.09e-1)" "unprognostic (9.48e-2)" "unprognostic (5.81e-2)" "unprognostic (1.04e-1)" "unprognostic (4.06e-1)" "unprognostic (1.39e-2)" "unprognostic (1.35e-2)" "unprognostic (8.15e-3)" "unprognostic (6.99e-2)" "unprognostic (8.16e-2)" "unprognostic (1.97e-1)" "unprognostic (3.80e-1)" "unprognostic (2.20e-1)" "unprognostic (1.69e-1)" "unprognostic (4.61e-2)" "unprognostic (1.55e-1)" THOC3 "MGC5469, TEX1" ENSG00000051596 "THO complex subunit 3" Q96J01 5 175917873-176034680 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, mRNA transport, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 106.0;Esophageal apical cells: 43.4;Late primary spermatocytes: 61.9;Late spermatids: 59.5;Papillary tip epithelial cells: 111.6;Renal connecting tubule cells: 62.2" "Cell type enhanced" "Detected in many" "Renal nephron cells: 111.6;Spermatogenic cell types: 106.0" "Cell type enriched" "Detected in all" 8 "hippocampal dentate gyrus: 125.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA042764, HPA044009, HPA045071" Approved Supported Nucleoplasm,Vesicles No No 15000 "Cluster 43: Non-specific - Transcription & Translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 29: Forebrain - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 105: Non-specific - Mixed function" 47 Nucleoplasm Vesicles "HPA042764: , HPA044009: , HPA045071: " "potential prognostic unfavorable (1.51e-4)" "unprognostic (2.54e-1)" "unprognostic (7.00e-2)" "potential prognostic favorable (3.28e-4)" "unprognostic (1.24e-1)" "unprognostic (9.94e-2)" "unprognostic (7.99e-2)" "unprognostic (1.23e-1)" "unprognostic (4.46e-3)" "unprognostic (2.52e-2)" "unprognostic (9.38e-2)" "unprognostic (3.12e-1)" "unprognostic (3.80e-3)" "unprognostic (3.46e-3)" "unprognostic (3.69e-3)" "unprognostic (7.52e-3)" "unprognostic (3.27e-2)" "unprognostic (8.66e-3)" "unprognostic (2.48e-1)" "unprognostic (6.64e-2)" "unprognostic (3.82e-2)" "unprognostic (8.41e-3)" "unprognostic (2.53e-1)" "unprognostic (2.60e-2)" "unprognostic (3.86e-3)" "unprognostic (3.30e-2)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (2.67e-1)" "unprognostic (3.45e-1)" "unprognostic (3.16e-1)" THOC6 "fSAP35, MGC2655, WDR58" ENSG00000131652 "THO complex subunit 6" Q86W42 16 3024027-3027755 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Apoptosis, mRNA processing, mRNA splicing, mRNA transport, Transport" "Developmental protein, RNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 123.4;Esophageal basal cells: 75.7;Extravillous trophoblasts: 143.5;Migrating cytotrophoblasts: 152.4;Syncytiotrophoblasts: 80.5" "Cell type enhanced" "Detected in all" "Trophoblast cells: 152.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enriched" "Detected in many" "intestine: 27183969.4" HPA052953 Uncertain Supported "Nucleoplasm,Nuclear speckles" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 18 "Nucleoplasm, Nuclear speckles" "HPA052953: " "unprognostic (5.98e-2)" "unprognostic (1.34e-1)" "unprognostic (2.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.14e-1)" "unprognostic (2.12e-1)" "unprognostic (2.82e-2)" "unprognostic (1.38e-2)" "unprognostic (3.40e-1)" "unprognostic (1.16e-1)" "unprognostic (3.04e-3)" "unprognostic (3.11e-1)" "unprognostic (1.97e-1)" "unprognostic (2.39e-2)" "unprognostic (1.96e-2)" "unprognostic (1.46e-1)" "unprognostic (1.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.79e-2)" "unprognostic (8.59e-2)" "unprognostic (7.26e-2)" "unprognostic (3.68e-2)" "unprognostic (8.13e-2)" "unprognostic (8.32e-3)" "unprognostic (8.73e-2)" "unprognostic (1.09e-1)" "unprognostic (6.95e-2)" "unprognostic (1.54e-1)" "unprognostic (2.28e-1)" "unprognostic (9.82e-2)" "unprognostic (1.61e-1)" THSD1 TMTSP ENSG00000136114 "Thrombospondin type 1 domain containing 1" Q9NS62 13 52377167-52416373 "Disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 42.0;Epididymal basal cells: 39.6;Fibro-adipogenic progenitors: 30.7;Lymphatic endothelial cells: 74.7;Myosatellite cells: 21.7;Retinal bipolar cells: 27.5;Retinal ganglion cells: 46.4;Vascular endothelial cells: 43.3" "Cell type enhanced" "Detected in many" "Basal cells: 39.6;Endothelial cells: 74.7;Glial cells: 42.0;Neuronal cells: 46.4" "Group enriched" "Detected in all" 4 "astrocyte: 28.8;endothelial cell: 105.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Endothelial cells, Colon - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012611, CAB020796, HPA071106" Supported Supported Cytosol "Intracellular and membrane" "No annotated function" No No 260000 "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 51: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Cytosol "CAB020796: , HPA012611: , HPA071106: " "unprognostic (6.78e-2)" "unprognostic (6.95e-2)" "unprognostic (4.48e-1)" "unprognostic (1.39e-2)" "unprognostic (1.10e-1)" "unprognostic (2.03e-2)" "unprognostic (3.62e-1)" "unprognostic (3.88e-2)" "unprognostic (3.03e-2)" "unprognostic (1.31e-1)" "unprognostic (1.75e-3)" "potential prognostic favorable (7.89e-5)" "unprognostic (5.07e-2)" "unprognostic (1.17e-1)" "unprognostic (1.45e-3)" "unprognostic (1.05e-3)" "unprognostic (1.44e-1)" "unprognostic (2.17e-2)" "unprognostic (2.18e-2)" "unprognostic (1.13e-3)" "unprognostic (2.63e-2)" "unprognostic (1.68e-1)" "unprognostic (9.25e-3)" "unprognostic (2.96e-2)" "unprognostic (1.30e-1)" "unprognostic (1.47e-2)" "unprognostic (2.41e-1)" "unprognostic (6.57e-2)" "unprognostic (8.61e-2)" THUMPD2 "C2orf8, MGC2454" ENSG00000138050 "THUMP domain containing 2" Q9BTF0 2 39736060-39779267 "Predicted intracellular proteins" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Oocytes: 144988.1" "Not detected" "Not detected" "HPA043042, HPA058025" Approved Uncertain Nucleoplasm Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 24: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 7: Non-specific - Transcription" 2 Nucleoplasm "HPA043042: , HPA058025: " "unprognostic (2.25e-1)" "unprognostic (6.00e-2)" "unprognostic (3.62e-3)" "unprognostic (8.15e-2)" "unprognostic (6.25e-3)" "unprognostic (1.52e-1)" "unprognostic (4.42e-2)" "potential prognostic unfavorable (5.98e-5)" "unprognostic (1.38e-1)" "unprognostic (1.27e-2)" "unprognostic (3.91e-2)" "unprognostic (1.72e-1)" "unprognostic (1.49e-1)" "unprognostic (1.92e-2)" "unprognostic (2.36e-1)" "unprognostic (7.69e-2)" "unprognostic (1.78e-2)" THUMPD3 DKFZP434F091 ENSG00000134077 "THUMP domain containing 3" Q9BV44 3 9362971-9386791 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 261.3;Late primary spermatocytes: 391.8;Late spermatids: 177.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 391.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA036170, HPA036171" Approved Enhanced Nucleoli,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 11 Cytosol Nucleoli "HPA036170: , HPA036171: " "unprognostic (3.86e-1)" "unprognostic (3.17e-2)" "unprognostic (3.17e-1)" "unprognostic (1.98e-1)" "unprognostic (2.88e-1)" "unprognostic (8.59e-2)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (4.86e-2)" "unprognostic (1.17e-3)" "potential prognostic favorable (2.22e-5)" "unprognostic (4.40e-1)" "unprognostic (2.42e-1)" "potential prognostic unfavorable (6.08e-6)" "unprognostic (4.27e-2)" "unprognostic (2.94e-3)" "unprognostic (7.88e-3)" "unprognostic (1.28e-1)" "unprognostic (2.63e-1)" "unprognostic (7.50e-2)" "unprognostic (3.39e-2)" "unprognostic (5.66e-3)" "unprognostic (8.51e-2)" "unprognostic (1.90e-2)" "unprognostic (8.62e-3)" "unprognostic (1.05e-1)" "unprognostic (2.02e-1)" "unprognostic (9.53e-2)" "unprognostic (1.59e-1)" "unprognostic (6.93e-2)" "unprognostic (2.60e-1)" TIAM1 ENSG00000156299 "TIAM Rac1 associated GEF 1" Q13009 21 31118416-31559977 "Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Epilepsy, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 264.4" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 848.5;Corticotrophs: 847.3;Epididymal basal cells: 501.8;Esophageal apical cells: 615.2;Esophageal suprabasal cells: 509.4;Microglia: 499.0;Ocular epithelial cells: 708.3;Retinal horizontal cells: 585.0;Suprabasal keratinocytes: 874.0;Urothelial cells: 693.9" "Cell type enhanced" "Detected in all" "Neuronal cells: 848.5;Pituitary endocrine cells: 847.3;Suprabasal cells: 874.0" "Cell type enhanced" "Detected in all" "upper rhombic lip: 2286.5" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 43.2" "Region enriched" "Detected in all" 4 "cerebellum: 330.3" "Immune cell enhanced" "Detected in many" "T-reg: 33.6" "Group enriched" "Detected in many" 4 "monocytes: 12.4;T-cells: 33.6" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal medulla cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 363.0" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 2228875.1;Neurons: 4469121.7" "Tissue enriched" "Detected in some" "cerebral cortex: 10637632.0" "CAB010416, HPA034853" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cell Junctions,Cytokinetic bridge,Cytosol" Yes NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 69: Skin cancer - ECM organization" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 27 "Nucleoplasm, Cell Junctions" "Nuclear membrane, Cytokinetic bridge, Cytosol" "CAB010416: , HPA034853: " "potential prognostic favorable (4.77e-5)" "unprognostic (1.52e-1)" "unprognostic (6.85e-2)" "unprognostic (1.92e-2)" "unprognostic (4.54e-2)" "unprognostic (3.26e-1)" "unprognostic (3.03e-1)" "unprognostic (5.15e-3)" "unprognostic (3.86e-3)" "unprognostic (4.42e-2)" "unprognostic (1.87e-1)" "unprognostic (7.47e-2)" "unprognostic (5.05e-2)" "unprognostic (9.16e-2)" "potential prognostic favorable (1.51e-5)" "unprognostic (3.62e-1)" "unprognostic (3.31e-2)" "unprognostic (3.55e-1)" "unprognostic (2.64e-2)" "unprognostic (1.24e-2)" "unprognostic (3.87e-1)" "unprognostic (4.23e-3)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (1.54e-1)" "unprognostic (3.67e-2)" "unprognostic (7.24e-3)" "unprognostic (1.70e-1)" "unprognostic (5.01e-2)" "unprognostic (1.59e-1)" "potential prognostic favorable (6.81e-4)" "unprognostic (1.51e-1)" TIAM2 STEF ENSG00000146426 "TIAM Rac1 associated GEF 2" Q8IVF5 6 154832697-155257723 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.9;testis: 12.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 552.7;Late spermatids: 479.3;Myonuclei: 418.5;Pituitary stem cells: 361.0" "Cell type enhanced" "Detected in all" "Neuronal cells: 552.7;Spermatogenic cell types: 479.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 6.4;non-classical monocyte: 9.5" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 50.7" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 11451903.3;Microglia and Neuropil: 10420360.6;Neurons: 11632438.0" "Tissue enriched" "Detected in single" 264022 "cerebral cortex: 26402183.4" "HPA011134, HPA013903" Approved Supported "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 53: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 7: Non-specific - Transcription" 9 "Nucleoplasm, Nucleoli fibrillar center" Cytosol "HPA011134: , HPA013903: " "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (8.52e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-3)" "unprognostic (4.67e-2)" "unprognostic (6.12e-2)" "unprognostic (2.89e-1)" "unprognostic (2.37e-1)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.43e-2)" "unprognostic (1.15e-1)" "unprognostic (6.77e-3)" "unprognostic (2.25e-1)" "unprognostic (6.40e-3)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (1.50e-2)" "unprognostic (3.31e-2)" TICRR "C15orf42, FLJ41618, MGC45866, SLD3, Treslin" ENSG00000140534 "TOPBP1 interacting checkpoint and replication regulator" Q7Z2Z1 15 89575469-89631056 "Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 3.2;esophagus: 4.0;lymphoid tissue: 3.9" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 10.8;Cardiomyocytes: 9.3;Differentiating spermatogonia: 10.5;Early primary spermatocytes: 15.0;Epicardial cells: 15.9;Erythrocyte progenitors: 24.1;Esophageal basal cells: 16.3;Extravillous trophoblasts: 11.4;Megakaryocyte progenitors: 20.2;Monocyte progenitors: 34.5;Neutrophil progenitors: 14.2" "Cell type enhanced" "Detected in many" "Erythrocytes: 24.1;Megakaryocytes: 20.2;Mononuclear phagocytes: 34.5" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 8229 "Hepatocytes: 822857.7" "Tissue enriched" "Detected in some" "kidney: 896899.7" "HPA046746, HPA049454" Supported Nucleoplasm NA Yes "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 58: Non-specific - Nuclear processes" "Cluster 27: Non-specific - Cell proliferation" 9 Nucleoplasm "HPA046746: , HPA049454: " "unprognostic (2.13e-2)" "unprognostic (2.69e-2)" "unprognostic (1.63e-2)" "unprognostic (2.97e-1)" "unprognostic (2.61e-2)" "unprognostic (2.20e-1)" "unprognostic (2.36e-2)" "unprognostic (3.12e-1)" "validated prognostic unfavorable (1.80e-4)" "validated prognostic unfavorable (8.13e-5)" "unprognostic (1.23e-1)" "unprognostic (1.07e-3)" "unprognostic (2.65e-1)" "unprognostic (7.39e-3)" "unprognostic (1.83e-3)" "unprognostic (9.16e-2)" "unprognostic (1.45e-1)" "unprognostic (1.82e-3)" "unprognostic (3.09e-2)" "unprognostic (7.50e-2)" "unprognostic (4.99e-2)" TIGD1 EEYORE ENSG00000221944 "Tigger transposable element derived 1" Q96MW7 2 232543883-232550557 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Myonuclei: 92.1;Thymic myoid cells: 35.4" "Group enriched" "Detected in many" 5 "Myocytes: 92.1;Stromal cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA041717 Approved Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 21: Neutrophils - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 56: Non-specific - Sensory perception" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 4 "Nucleoli rim, Mitotic chromosome" "Nucleoplasm, Nuclear bodies" "HPA041717: " "unprognostic (1.64e-3)" "unprognostic (6.27e-2)" "unprognostic (1.23e-1)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (2.54e-5)" "unprognostic (5.70e-2)" "unprognostic (5.17e-3)" "unprognostic (6.36e-2)" "unprognostic (1.91e-1)" "unprognostic (8.67e-3)" "potential prognostic unfavorable (1.72e-5)" "unprognostic (2.82e-1)" "unprognostic (1.96e-1)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (8.21e-2)" "unprognostic (1.30e-1)" "unprognostic (4.22e-2)" "unprognostic (2.28e-2)" "potential prognostic favorable (2.46e-5)" "unprognostic (4.08e-2)" "unprognostic (9.84e-2)" "unprognostic (9.82e-2)" "unprognostic (5.66e-3)" "unprognostic (2.90e-2)" "unprognostic (1.17e-2)" "unprognostic (1.47e-2)" "unprognostic (2.97e-2)" "unprognostic (3.00e-1)" "unprognostic (2.21e-2)" "unprognostic (8.90e-2)" "unprognostic (2.14e-1)" TIMELESS "hTIM, TIM, TIM1" ENSG00000111602 "Timeless circadian regulator" Q9UNS1 12 56416363-56449426 "Disease related genes, Essential proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Cell division, DNA damage, DNA repair, Mitosis, Transcription, Transcription regulation" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 33.8;Erythrocyte progenitors: 43.9;Gastric progenitor cells: 29.5;Gonadotrophs: 31.9;Megakaryocyte progenitors: 39.9;Monocyte progenitors: 44.0;Retinal bipolar cells: 54.5;Undifferentiated spermatogonia: 28.8" "Cell type enhanced" "Detected in many" "Neuronal cells: 54.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Granulosa cells: 2683997.0;Neutrophils: 1570948.4;Oocytes: 2700839.7" "Not detected" "Not detected" HPA060655 Enhanced Supported Nucleoplasm No No "Cluster 14: Non-specific - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 17 Nucleoplasm "HPA060655: " "unprognostic (1.50e-1)" "unprognostic (1.92e-2)" "unprognostic (3.71e-2)" "unprognostic (1.78e-1)" "unprognostic (2.00e-2)" "unprognostic (1.86e-1)" "unprognostic (3.56e-1)" "unprognostic (2.93e-1)" "unprognostic (8.61e-2)" "potential prognostic unfavorable (5.63e-5)" "unprognostic (5.47e-3)" "unprognostic (6.76e-2)" "unprognostic (1.09e-1)" "validated prognostic unfavorable (7.00e-4)" "validated prognostic unfavorable (2.71e-4)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (4.13e-3)" "unprognostic (1.14e-1)" "unprognostic (1.64e-2)" "unprognostic (5.99e-2)" "unprognostic (3.86e-2)" "unprognostic (7.23e-2)" "unprognostic (9.53e-3)" "unprognostic (8.42e-2)" "unprognostic (7.58e-3)" "unprognostic (5.01e-2)" "potential prognostic unfavorable (4.55e-4)" "unprognostic (5.56e-2)" "unprognostic (3.34e-1)" "unprognostic (7.02e-2)" "unprognostic (2.25e-1)" TIRAP "Mal, wyatt" ENSG00000150455 "TIR domain containing adaptor protein" P58753 11 126282497-126298845 "Predicted intracellular proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2821 "salivary gland: 282104.2" HPA054431 Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes NA "Cluster 7: Non-specific - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 24: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 32 "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA054431: " "unprognostic (2.20e-1)" "unprognostic (3.40e-3)" "unprognostic (2.06e-1)" "unprognostic (7.53e-2)" "unprognostic (1.96e-1)" "unprognostic (8.47e-3)" "unprognostic (1.51e-1)" "unprognostic (3.09e-1)" "unprognostic (4.90e-2)" "unprognostic (8.13e-2)" "validated prognostic favorable (4.15e-8)" "validated prognostic favorable (4.01e-4)" "unprognostic (3.36e-2)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-3)" "unprognostic (2.14e-1)" "unprognostic (1.86e-1)" "unprognostic (1.58e-2)" "unprognostic (2.46e-1)" "unprognostic (3.65e-2)" "unprognostic (7.45e-2)" "unprognostic (3.64e-1)" "unprognostic (1.98e-1)" "unprognostic (4.59e-2)" "unprognostic (1.65e-1)" "unprognostic (6.81e-2)" "unprognostic (1.57e-2)" "unprognostic (3.16e-1)" "unprognostic (5.84e-2)" "unprognostic (1.28e-1)" TKFC "DAK, DKFZP586B1621, NET45" ENSG00000149476 "Triokinase and FMN cyclase" Q3LXA3 11 61333220-61353295 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Lyase, Multifunctional enzyme, Transferase" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 181.3;liver: 108.3" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 64.8;Enteric transient amplifying cells: 71.9;Enterocytes: 374.6;Hepatocytes: 154.0" "Cell type enhanced" "Detected in many" "Enterocytes: 374.6;Hepatocytes: 154.0" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Liver - Hepatocytes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Glomeruli: 284478736.8;Hepatocytes: 805049283.8;Proximal tubules: 715784232.5" "Tissue enriched" "Detected in all" "liver: 1006129258.4" "HPA039486, HPA048186" Enhanced Approved Nucleoplasm,Cytosol NA NA 7600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 77: Intestine - Digestion" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" 22 Nucleoplasm Cytosol "HPA039486: , HPA048186: " "unprognostic (8.96e-2)" "unprognostic (8.60e-2)" "unprognostic (2.94e-1)" "unprognostic (1.30e-1)" "unprognostic (1.73e-2)" "unprognostic (1.11e-1)" "unprognostic (1.22e-1)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "potential prognostic favorable (2.11e-8)" "unprognostic (4.53e-1)" "unprognostic (1.42e-2)" "unprognostic (1.88e-2)" "potential prognostic unfavorable (2.03e-4)" "unprognostic (1.15e-2)" "unprognostic (9.07e-2)" "unprognostic (2.62e-1)" "unprognostic (1.18e-1)" "unprognostic (4.40e-2)" "unprognostic (4.50e-2)" "unprognostic (6.28e-2)" "unprognostic (1.53e-1)" "unprognostic (5.58e-3)" "unprognostic (2.16e-1)" "unprognostic (1.92e-1)" "unprognostic (6.86e-2)" "unprognostic (2.02e-1)" "unprognostic (4.11e-1)" "unprognostic (1.53e-2)" TKT ENSG00000163931 Transketolase P29401 3 53224712-53256052 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 630.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 934.6;Alveolar cells type 2: 608.2;Esophageal basal cells: 1040.5;Esophageal suprabasal cells: 608.3;Kupffer cells: 614.9;Neutrophil progenitors: 804.2;Neutrophils: 790.7;Ocular epithelial cells: 1019.4" "Cell type enhanced" "Detected in all" "Alveolar cells: 934.6;Barrier epithelial cells: 1019.4;Basal cells: 1040.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 447.4;eosinophil: 274.7;intermediate monocyte: 198.7;myeloid DC: 204.0;neutrophil: 376.1;non-classical monocyte: 243.2" "Group enriched" "Detected in all" 9 "dendritic cells: 204.0;granulocytes: 376.1;monocytes: 447.4" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA029480, HPA029481" Enhanced Enhanced "Nucleoplasm,Nuclear speckles,Nuclear bodies" NA NA 120000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 15: Bone marrow - Innate immune response" "Cluster 19: Astrocytes - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 100: Stratified epithelial cells - Barrier functions" 22 Nucleoplasm "Nuclear speckles, Nuclear bodies" "HPA029480: , HPA029481: " "potential prognostic unfavorable (8.65e-4)" "unprognostic (1.02e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.28e-3)" "unprognostic (8.66e-2)" "unprognostic (1.34e-1)" "unprognostic (1.08e-1)" "unprognostic (1.00e-2)" "unprognostic (5.83e-2)" "unprognostic (1.37e-2)" "unprognostic (5.15e-3)" "unprognostic (1.97e-3)" "validated prognostic unfavorable (8.71e-6)" "validated prognostic unfavorable (1.38e-5)" "unprognostic (1.93e-1)" "unprognostic (3.64e-2)" "unprognostic (1.68e-1)" "unprognostic (3.02e-1)" "unprognostic (1.11e-1)" "unprognostic (4.44e-2)" "potential prognostic unfavorable (4.35e-4)" "unprognostic (9.83e-2)" "unprognostic (3.12e-2)" "unprognostic (1.16e-2)" "unprognostic (3.09e-2)" "unprognostic (2.46e-1)" "unprognostic (2.29e-1)" "unprognostic (5.31e-2)" "unprognostic (1.21e-1)" "unprognostic (1.91e-1)" TKTL1 "TKR, TKT2" ENSG00000007350 "Transketolase like 1" P51854 X 154295795-154330350 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 33 "testis: 118.9" "Group enriched" "Detected in some" 11 "Differentiating spermatogonia: 678.2;Early primary spermatocytes: 371.4;Oocytes: 437.5;Undifferentiated spermatogonia: 202.8" "Group enriched" "Detected in many" 16 "Oocytes: 437.5;Spermatogenic cell types: 678.2" "Cell type enhanced" "Detected in some" "leukocyte: 5.0" "Cancer enriched" "Detected in many" 6 "Testicular Germ Cell Tumor (TCGA): 93.1" "Group enriched" "Detected in some" 7 "cerebral cortex: 8.7;medulla oblongata: 3.1" "Group enriched" "Detected in many" 5 "eosinophil: 61.0;gdT-cell: 24.5" "Group enriched" "Detected in many" 5 "granulocytes: 61.0;T-cells: 24.5" "Cancer enhanced" "Detected in some" "Gallbladder cancer: 11.4;Myeloma: 6.8" "Heart muscle - Cardiomyocytes, Lung - NK-cells (Lung), Testis - Spermatocytes, Testis - Spermatogonia" "Not detected" "Not detected" "Region enhanced" "Detected in single" "white matter: 1.3" "Cell type enriched" "Detected in single" 493 "Oocytes: 49344.0" "Tissue enriched" "Detected in single" 102 "lymphoid tissue: 10226.6" "HPA000505, HPA029155, CAB032191" Enhanced Enhanced Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 Cytosol "CAB032191: , HPA000505: , HPA029155: " "unprognostic (3.41e-2)" "unprognostic (4.47e-1)" "unprognostic (3.05e-3)" "unprognostic (1.22e-2)" "unprognostic (5.93e-2)" "unprognostic (8.64e-2)" "unprognostic (4.75e-3)" "unprognostic (1.68e-1)" "unprognostic (7.44e-2)" "unprognostic (1.57e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" "unprognostic (6.76e-2)" "unprognostic (1.42e-2)" "unprognostic (5.64e-2)" "unprognostic (1.21e-2)" TLCD4 "FLJ31842, TMEM56" ENSG00000152078 "TLC domain containing 4" Q96MV1 1 95117355-95197607 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 121.5" "Cell type enhanced" "Detected in some" "Astrocytes: 70.9;Bergmann glia: 70.0;Brain excitatory neurons: 36.4;Brain inhibitory neurons: 40.1;Choroid plexus epithelial cells: 23.3;Ependymal cells: 20.5;Erythrocyte progenitors: 15.4;Late spermatids: 18.3;Oligodendrocyte progenitor cells: 39.6;Oligodendrocytes: 36.8;Other brain neurons: 19.5;Retinal pigment epithelial cells: 25.6" "Cell type enhanced" "Detected in some" "Ciliated cells: 23.3;Glial cells: 70.9;Neuronal cells: 40.1;Pigment cells: 25.6;Spermatogenic cell types: 18.3" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 19.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Smooth muscle cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 1652513.3" "Group enriched" "Detected in some" 1989 "cerebral cortex: 104793.4;liver: 383920.4;salivary gland: 108000.6" HPA046762 Approved "Nuclear speckles" No No "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 31: Non-specific - Transcription" "Cluster 15: Kidney cancer - Membrane components" "Cluster 28: Astrocytes - Homeostasis & neuron support" 63 "Nuclear speckles" "HPA046762: " "unprognostic (7.65e-3)" "unprognostic (4.17e-3)" "unprognostic (8.33e-2)" "unprognostic (2.93e-3)" "unprognostic (1.99e-2)" "unprognostic (3.74e-2)" "unprognostic (2.95e-2)" "potential prognostic unfavorable (3.20e-4)" "unprognostic (3.39e-3)" "unprognostic (1.84e-1)" "unprognostic (1.68e-2)" "unprognostic (1.35e-2)" "unprognostic (3.00e-2)" "unprognostic (7.77e-3)" "unprognostic (1.63e-1)" "unprognostic (7.80e-3)" "unprognostic (3.01e-2)" "unprognostic (6.70e-2)" "unprognostic (1.39e-1)" "unprognostic (3.23e-1)" "unprognostic (1.15e-1)" "unprognostic (6.15e-2)" "unprognostic (4.25e-2)" "unprognostic (3.71e-3)" "unprognostic (1.16e-1)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (1.87e-1)" TLE3 "ESG, ESG3, GRG3, HsT18976, KIAA1547" ENSG00000140332 "TLE family member 3, transcriptional corepressor" Q04726 15 70047790-70098176 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.6" "Cell type enriched" "Detected in many" 4 "Neutrophils: 595.7" "Cell type enriched" "Detected in many" 4 "Neutrophils: 595.7" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 91.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 49.3" "Lineage enriched" "Detected in all" 5 "granulocytes: 49.3" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 3256789.0;Smooth muscle cells: 2779546.2" "Group enriched" "Detected in many" "cerebral cortex: 450961.9;fallopian tube: 570986.1;lymphoid tissue: 1009577.7;ovary: 542041.5" HPA054116 Approved Supported Nucleoplasm,Cytosol NA Yes "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 41 Nucleoplasm Cytosol "HPA054116: " "unprognostic (3.90e-1)" "unprognostic (1.84e-1)" "unprognostic (1.12e-1)" "unprognostic (4.25e-2)" "unprognostic (2.76e-1)" "unprognostic (3.84e-2)" "unprognostic (1.79e-1)" "potential prognostic favorable (1.63e-4)" "unprognostic (8.91e-2)" "unprognostic (1.55e-1)" "potential prognostic favorable (8.32e-4)" "unprognostic (2.83e-2)" "unprognostic (1.09e-1)" "unprognostic (1.09e-2)" "potential prognostic unfavorable (2.81e-4)" "unprognostic (2.87e-1)" "unprognostic (2.23e-2)" "unprognostic (7.06e-2)" "unprognostic (1.88e-2)" "unprognostic (6.17e-3)" "unprognostic (1.80e-1)" "unprognostic (1.08e-1)" "unprognostic (1.02e-2)" "unprognostic (3.07e-2)" "unprognostic (1.73e-1)" "unprognostic (1.16e-1)" "unprognostic (1.82e-1)" "unprognostic (3.22e-1)" "unprognostic (3.55e-1)" "unprognostic (5.49e-2)" "unprognostic (3.98e-2)" TLE4 "E(spl), ESG, GRG4" ENSG00000106829 "TLE family member 4, transcriptional corepressor" Q04727 9 79571773-79726882 "Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 94.4" "Cell type enhanced" "Detected in all" "Early spermatids: 1051.1;Endometrial ciliated cells: 870.6;Lactotrophs: 1586.6;Late spermatids: 2003.5;Neutrophil progenitors: 901.6;Neutrophils: 1303.7" "Cell type enhanced" "Detected in all" "Pituitary endocrine cells: 1586.6;Spermatogenic cell types: 2003.5" "Cell type enhanced" "Detected in all" "deep-layer corticothalamic and 6b: 902.4;deep-layer near-projecting: 904.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 22.0" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast myoepithelial cells, Pituitary gland - Lactotropes, Prostate - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 1456137.0" "Tissue enriched" "Detected in single" 255 "lymphoid tissue: 25528.4" HPA065357 Supported Nucleoplasm,Mitochondria NA NA "Cluster 41: Basophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 Nucleoplasm Mitochondria "HPA065357: " "unprognostic (2.71e-2)" "unprognostic (8.74e-2)" "unprognostic (9.43e-2)" "unprognostic (8.24e-2)" "unprognostic (1.05e-3)" "unprognostic (1.82e-3)" "unprognostic (4.59e-1)" "unprognostic (3.74e-1)" "unprognostic (2.06e-1)" "unprognostic (2.46e-3)" "potential prognostic favorable (1.42e-4)" "unprognostic (6.70e-2)" "unprognostic (1.58e-3)" "unprognostic (8.82e-2)" "unprognostic (2.02e-3)" "unprognostic (1.98e-1)" "unprognostic (7.92e-2)" "unprognostic (1.25e-1)" "unprognostic (2.85e-1)" "unprognostic (5.05e-2)" "unprognostic (1.42e-1)" "unprognostic (7.38e-2)" "unprognostic (2.48e-1)" "unprognostic (1.53e-1)" "unprognostic (3.40e-1)" "unprognostic (2.46e-1)" "unprognostic (1.91e-1)" "unprognostic (4.43e-2)" "unprognostic (2.37e-1)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" TLX3 "HOX11L2, RNX" ENSG00000164438 "T cell leukemia homeobox 3" O43711 5 171309248-171312139 "Cancer-related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 79 "brain: 24.0" "Group enriched" "Detected in some" 5 "Brain excitatory neurons: 4.5;Extravillous trophoblasts: 10.7;Oocytes: 4.6" "Group enriched" "Detected in some" 11 "Neuronal cells: 4.5;Oocytes: 4.6;Trophoblast cells: 10.7" "Cell type enriched" "Detected in some" 4 "upper rhombic lip: 11.1" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.8" "Group enriched" "Detected in some" 5 "cerebellum: 18.6;medulla oblongata: 5.0;spinal cord: 11.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 8.4" "Pituitary gland - Thyrotropes" "Region enriched" "Detected in single" 7 "cerebellum: 2.2" "Region enriched" "Detected in some" 9 "cerebellum: 16.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030504, HPA060957, HPA069359" Enhanced Enhanced Nucleoplasm NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 59: Leukemia - T-cell receptor" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 76 Nucleoplasm "HPA030504: , HPA060957: , HPA069359: " "unprognostic (2.95e-1)" "unprognostic (2.75e-2)" "unprognostic (4.87e-2)" "unprognostic (3.20e-1)" "unprognostic (4.21e-2)" TM2D3 "BLP2, FLJ22604" ENSG00000184277 "TM2 domain containing 3" Q9BRN9 15 101621444-101652391 "Predicted intracellular proteins, Predicted membrane proteins" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 285.5" "Cell type enhanced" "Detected in all" "Oocytes: 285.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 136042.1;Pancreas epithelial cells: 131162.8" "Not detected" "Not detected" HPA054064 Uncertain Approved Nucleoplasm,Cytosol Yes No 27000 "Cluster 21: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 31 Nucleoplasm Cytosol "HPA054064: " "unprognostic (2.74e-1)" "unprognostic (8.55e-2)" "potential prognostic favorable (1.60e-4)" "unprognostic (3.83e-1)" "unprognostic (4.11e-2)" "unprognostic (1.09e-1)" "unprognostic (9.13e-3)" "unprognostic (1.21e-2)" "unprognostic (3.60e-2)" "unprognostic (4.79e-1)" "unprognostic (2.65e-3)" "unprognostic (2.13e-2)" "unprognostic (5.17e-2)" "unprognostic (1.85e-1)" "unprognostic (1.52e-2)" "unprognostic (9.09e-2)" "unprognostic (1.01e-1)" "unprognostic (2.47e-2)" "unprognostic (9.92e-2)" "unprognostic (5.08e-2)" "unprognostic (1.38e-1)" "unprognostic (3.96e-2)" "unprognostic (5.59e-2)" "unprognostic (1.55e-1)" "unprognostic (9.14e-2)" "unprognostic (2.13e-1)" "unprognostic (1.75e-2)" "unprognostic (6.48e-2)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" TMA7 "CCDC72, HSPC016" ENSG00000232112 "Translation machinery associated 7 homolog" Q9Y2S6 3 48440257-48444208 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1589.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2695 "kidney: 269522.1" HPA047397 Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies" Yes No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Protein processing" 1 "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies" "HPA047397: " "unprognostic (3.73e-2)" "unprognostic (3.82e-2)" "unprognostic (4.97e-2)" "unprognostic (1.69e-1)" "unprognostic (1.34e-2)" "unprognostic (2.26e-1)" "unprognostic (7.14e-2)" "unprognostic (2.41e-2)" "potential prognostic unfavorable (4.51e-4)" "unprognostic (6.50e-3)" "unprognostic (5.69e-2)" "unprognostic (3.15e-2)" "unprognostic (6.93e-3)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "potential prognostic favorable (1.62e-4)" "unprognostic (6.30e-2)" "unprognostic (3.18e-3)" "unprognostic (1.95e-1)" "unprognostic (4.70e-2)" "unprognostic (4.31e-1)" "unprognostic (1.60e-2)" "unprognostic (9.84e-2)" "unprognostic (3.97e-2)" "unprognostic (3.29e-2)" "unprognostic (2.13e-2)" "unprognostic (2.17e-2)" "unprognostic (1.84e-1)" "unprognostic (7.63e-2)" TMBIM1 "LFG3, PP1201, RECS1" ENSG00000135926 "Transmembrane BAX inhibitor motif containing 1" Q969X1 2 218274197-218292586 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 291.6;Esophageal apical cells: 1555.8;Esophageal suprabasal cells: 409.0;Pancreatic acinar cells: 351.3;Platelets: 633.8;Syncytiotrophoblasts: 368.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1555.8;Platelets: 633.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Heart muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA012093, HPA070824" Approved Supported Vesicles NA NA 14000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 7 Vesicles "HPA012093: , HPA070824: " "unprognostic (5.65e-2)" "unprognostic (1.82e-2)" "unprognostic (2.74e-1)" "unprognostic (1.02e-1)" "unprognostic (1.67e-1)" "unprognostic (2.66e-2)" "unprognostic (7.71e-3)" "potential prognostic unfavorable (4.61e-6)" "unprognostic (2.89e-2)" "unprognostic (1.72e-1)" "validated prognostic favorable (6.97e-11)" "validated prognostic favorable (9.38e-4)" "unprognostic (2.55e-1)" "unprognostic (1.92e-3)" "unprognostic (2.37e-2)" "unprognostic (1.76e-2)" "unprognostic (3.57e-1)" "unprognostic (4.34e-2)" "unprognostic (2.67e-3)" "unprognostic (1.34e-2)" "unprognostic (1.36e-1)" "unprognostic (3.45e-3)" "unprognostic (1.20e-1)" "unprognostic (2.12e-1)" "unprognostic (3.90e-1)" "unprognostic (7.18e-2)" "unprognostic (1.22e-1)" "unprognostic (9.79e-2)" "unprognostic (2.40e-1)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" TMCO6 "FLJ39769, PRO1580" ENSG00000113119 "Transmembrane and coiled-coil domains 6" Q96DC7 5 140639435-140645408 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 27.3;Differentiating spermatogonia: 21.4;Early primary spermatocytes: 21.9" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 58984.4;Oocytes: 36434.1;T-cells: 127057.4" "Not detected" "Not detected" "HPA037473, HPA037474" Uncertain Approved Nucleoplasm,Mitochondria No No "Cluster 35: Neutrophils - Protein binding" "Cluster 76: Non-specific - Metabolism" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 18: Adrenal cortex cells - Steroidogensis" 7 Mitochondria Nucleoplasm "HPA037473: , HPA037474: " "unprognostic (6.18e-2)" "unprognostic (7.68e-2)" "unprognostic (2.79e-1)" "unprognostic (1.08e-1)" "unprognostic (1.32e-1)" "unprognostic (4.98e-2)" "potential prognostic unfavorable (5.63e-4)" "unprognostic (2.78e-1)" "unprognostic (1.70e-1)" "unprognostic (2.22e-1)" "unprognostic (3.77e-3)" "unprognostic (3.09e-2)" "unprognostic (2.05e-1)" "unprognostic (5.60e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (9.07e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-1)" "unprognostic (2.07e-2)" "unprognostic (9.12e-2)" "unprognostic (1.21e-1)" "unprognostic (4.83e-2)" "unprognostic (6.66e-2)" "unprognostic (8.55e-2)" "unprognostic (3.86e-2)" "unprognostic (7.00e-3)" "unprognostic (4.18e-2)" "unprognostic (1.59e-1)" "unprognostic (8.11e-2)" "unprognostic (7.01e-2)" TMEM101 "FLJ23987, MGC4251" ENSG00000091947 "Transmembrane protein 101" Q96IK0 17 44011188-44023946 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Distal convoluted tubule cells: 254.2;Endometrial glandular cells: 434.3;Endometrial luminal cells: 777.2;Renal collecting duct intercalated cells: 794.7" "Group enriched" "Detected in all" 5 "Ductal cells: 794.7;Glandular cells: 434.3;Luminal cells: 777.2;Renal nephron cells: 254.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 300.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Kidney - Intercalated cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 444 "Collecting ducts: 44358.2" "Not detected" "Not detected" "HPA039739, HPA075651" Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 72: Kidney - Transmembrane transport" "Cluster 19: Astrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 15 "Nucleoplasm, Plasma membrane" "HPA039739: , HPA075651: " "unprognostic (2.53e-1)" "unprognostic (5.16e-3)" "unprognostic (4.44e-1)" "unprognostic (2.50e-1)" "unprognostic (1.32e-1)" "unprognostic (2.97e-2)" "unprognostic (3.22e-2)" "unprognostic (6.82e-3)" "unprognostic (3.56e-3)" "unprognostic (2.76e-2)" "potential prognostic favorable (8.44e-5)" "unprognostic (1.17e-1)" "unprognostic (2.47e-1)" "validated prognostic unfavorable (3.40e-4)" "validated prognostic unfavorable (1.73e-5)" "unprognostic (1.30e-1)" "unprognostic (8.54e-3)" "unprognostic (1.17e-1)" "unprognostic (8.86e-2)" "unprognostic (4.98e-2)" "unprognostic (1.07e-2)" "unprognostic (3.30e-1)" "unprognostic (7.53e-2)" "unprognostic (1.74e-1)" "unprognostic (1.58e-2)" "unprognostic (2.93e-1)" "unprognostic (2.47e-1)" "unprognostic (1.27e-1)" "unprognostic (2.77e-1)" "unprognostic (3.28e-1)" "unprognostic (2.20e-1)" TMEM11 "C17orf35, PM1, PMI" ENSG00000178307 "Transmembrane protein 11" P17152 17 21197954-21214176 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 160.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 160.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 15287607.0" "Low tissue specificity" "Detected in all" HPA062854 Supported Supported Mitochondria No No "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 49 Mitochondria "HPA062854: " "unprognostic (3.08e-1)" "unprognostic (1.93e-1)" "unprognostic (1.77e-1)" "unprognostic (1.11e-1)" "unprognostic (3.08e-1)" "unprognostic (2.70e-2)" "unprognostic (4.50e-2)" "unprognostic (2.10e-1)" "unprognostic (2.38e-1)" "unprognostic (3.00e-2)" "unprognostic (5.13e-2)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (2.94e-3)" "unprognostic (3.65e-3)" "potential prognostic unfavorable (8.81e-4)" "unprognostic (4.10e-2)" "unprognostic (3.27e-1)" "unprognostic (1.96e-1)" "unprognostic (7.87e-2)" "unprognostic (2.72e-1)" "unprognostic (3.97e-2)" "unprognostic (5.42e-2)" "unprognostic (3.65e-2)" "unprognostic (1.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.96e-3)" "unprognostic (1.39e-1)" "unprognostic (4.98e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-1)" TMEM123 "KCT3, PORIMIN" ENSG00000152558 "Transmembrane protein 123" Q8N131 11 102396332-102470384 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in all" "endothelial cell: 271.3;ependymal cell: 304.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 9157135.5" "Low tissue specificity" "Detected in many" "CAB026001, HPA062862" Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 11: T-cells - Unknown function" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 11: White matter - Signal transduction" "Cluster 24: Non-specific - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Golgi apparatus" "Vesicles, Cytosol" "CAB026001: , HPA062862: " "unprognostic (7.41e-3)" "unprognostic (1.82e-1)" "unprognostic (1.03e-1)" "unprognostic (4.75e-3)" "unprognostic (2.37e-1)" "unprognostic (2.42e-1)" "unprognostic (6.39e-2)" "unprognostic (2.02e-3)" "unprognostic (3.29e-2)" "unprognostic (1.35e-2)" "potential prognostic favorable (6.89e-5)" "unprognostic (9.96e-3)" "unprognostic (9.25e-2)" "unprognostic (1.18e-1)" "unprognostic (1.44e-1)" "unprognostic (1.35e-2)" "unprognostic (4.37e-3)" "unprognostic (4.53e-1)" "unprognostic (4.35e-1)" "unprognostic (2.00e-1)" "unprognostic (5.37e-2)" "potential prognostic unfavorable (3.63e-4)" "unprognostic (4.27e-1)" "unprognostic (6.56e-2)" "unprognostic (8.13e-3)" "unprognostic (1.72e-2)" "unprognostic (1.43e-3)" "unprognostic (1.41e-1)" "unprognostic (4.49e-1)" "unprognostic (2.33e-3)" "unprognostic (2.44e-1)" TMEM125 MGC17299 ENSG00000179178 "Transmembrane protein 125" Q96AQ2 1 43269983-43274002 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 64.4;lung: 71.4;pancreas: 85.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 155.2;Alveolar cells type 2: 196.8;Breast lactating cells: 94.1;Enterocytes: 147.1;Esophageal apical cells: 81.8;Oligodendrocytes: 86.3;Respiratory ciliated cells: 77.4;Transitional alveolar cells: 123.3" "Cell type enhanced" "Detected in many" "Alveolar cells: 196.8;Enterocytes: 147.1" "Cell type enriched" "Detected in many" 4 "oligodendrocyte: 111.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adipose visceral - Mesothelial cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Liver - Cholangiocytes, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Somatotropes, Prostate - Prostate glandular cells, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA015796 Approved Midbody,Cytosol Yes NA "Cluster 60: Stomach - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 81: Alveolar cells - Lung function" "Midbody, Cytosol" "HPA015796: " "unprognostic (1.87e-1)" "unprognostic (5.59e-2)" "unprognostic (7.20e-2)" "unprognostic (1.36e-1)" "unprognostic (3.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.80e-1)" "unprognostic (2.08e-1)" "unprognostic (7.76e-2)" "potential prognostic favorable (3.30e-4)" "validated prognostic favorable (5.72e-11)" "validated prognostic favorable (2.24e-5)" "potential prognostic favorable (8.27e-5)" "unprognostic (3.70e-2)" "unprognostic (1.19e-1)" "potential prognostic favorable (1.23e-6)" "unprognostic (9.52e-2)" "unprognostic (4.20e-3)" "unprognostic (3.59e-2)" "unprognostic (2.12e-1)" "unprognostic (6.71e-2)" "unprognostic (9.38e-2)" "unprognostic (1.13e-2)" "unprognostic (5.15e-2)" "unprognostic (9.55e-2)" "unprognostic (5.03e-2)" "unprognostic (3.78e-1)" "unprognostic (2.22e-2)" "unprognostic (2.05e-1)" "unprognostic (2.05e-1)" "unprognostic (3.40e-1)" TMEM132A "FLJ20539, GBP, HSPA5BP1" ENSG00000006118 "Transmembrane protein 132A" Q24JP5 11 60924460-60937159 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 105.8;choroid plexus: 107.2" "Cell type enhanced" "Detected in many" "Astrocytes: 101.1;Müller glia: 185.3;Retinal amacrine cells: 59.3;Retinal horizontal cells: 136.2;Retinal pigment epithelial cells: 132.2;Rod photoreceptor cells: 65.3" "Cell type enhanced" "Detected in many" "Glial cells: 185.3;Neuronal cells: 136.2;Pigment cells: 132.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 215.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Liver - Vascular endothelial cells, Minor Salivary Gland - Minor salivary glandular cells, Skin - Outer root sheath cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 2721547.5;Microglia and Neuropil: 5026032.1;Neurons: 2061326.1" "Tissue enriched" "Detected in some" "Stomach: 10277327.3" "HPA051979, HPA060492" Enhanced Supported Approved Mitochondria No No 1600000 "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 27: Breast cancer - Unknown function" "Cluster 11: Muller glia cells - Retinal homeostasis" Mitochondria "HPA051979: , HPA060492: " "unprognostic (1.25e-1)" "unprognostic (2.95e-2)" "unprognostic (1.47e-1)" "unprognostic (7.09e-2)" "unprognostic (1.87e-1)" "unprognostic (2.22e-2)" "unprognostic (4.63e-2)" "unprognostic (3.33e-2)" "unprognostic (3.41e-1)" "unprognostic (1.07e-3)" "validated prognostic unfavorable (1.72e-6)" "validated prognostic unfavorable (3.25e-4)" "unprognostic (1.80e-2)" "unprognostic (6.03e-3)" "unprognostic (4.22e-2)" "unprognostic (2.25e-2)" "unprognostic (1.02e-2)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" "unprognostic (9.59e-2)" "unprognostic (1.86e-1)" "unprognostic (1.54e-1)" "unprognostic (1.01e-3)" "unprognostic (4.61e-2)" "unprognostic (1.10e-1)" "unprognostic (2.53e-2)" "unprognostic (2.56e-1)" "unprognostic (2.72e-1)" "unprognostic (1.09e-2)" "unprognostic (7.80e-2)" "unprognostic (6.87e-2)" TMEM132E DFNB99 ENSG00000181291 "Transmembrane protein 132E" Q6IEE7 17 34579487-34639318 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 12.7" "Cell type enhanced" "Detected in some" "Astrocytes: 8.1;Brain excitatory neurons: 8.7;Brain inhibitory neurons: 9.4;cDC: 4.6;Differentiating spermatogonia: 5.4;Early primary spermatocytes: 7.1;Hepatic stellate cells: 6.5;Kupffer cells: 11.3;Late spermatids: 10.7;Oligodendrocyte progenitor cells: 17.6;Other brain neurons: 16.5;Proximal tubule cells: 11.9;Retinal amacrine cells: 21.5" "Cell type enhanced" "Detected in some" "Glial cells: 17.6;Mononuclear phagocytes: 11.3;Neuronal cells: 21.5;Renal nephron cells: 11.9;Spermatogenic cell types: 10.7" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Sarcoma: 3.9" "Kidney - Proximal tubular cells, Kidney - Proximal tubular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Collecting ducts: 839240.3" "Tissue enriched" "Detected in single" 6306 "cerebral cortex: 630585.9" HPA070608 Approved Approved "Nucleoplasm,Nuclear bodies,Golgi apparatus,Cytosol" NA NA 110000 "Cluster 27: Cerebellum - Synaptic function" "Cluster 44: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Golgi apparatus" "Nuclear bodies, Cytosol" "HPA070608: " "unprognostic (3.03e-1)" "unprognostic (2.63e-1)" "unprognostic (2.42e-1)" "unprognostic (2.75e-1)" "unprognostic (5.88e-2)" "unprognostic (1.09e-1)" TMEM134 FLJ21749 ENSG00000172663 "Transmembrane protein 134" Q9H6X4 11 67461710-67469272 "Predicted membrane proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 872.8;Esophageal basal cells: 296.1;Esophageal suprabasal cells: 584.2;Suprabasal keratinocytes: 230.2" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 872.8;Suprabasal cells: 584.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Prostate - Prostate glandular cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 3130 "Keratinocytes: 169855.4;Proximal tubules: 456192.0" "Group enriched" "Detected in some" 19944 "lymphoid tissue: 2211736.0;pancreas: 1777147.4" HPA043744 Approved Supported Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Ribosome" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" Cytosol "HPA043744: " "unprognostic (1.35e-2)" "unprognostic (2.61e-2)" "unprognostic (2.50e-1)" "unprognostic (1.17e-1)" "unprognostic (9.76e-2)" "unprognostic (2.69e-1)" "unprognostic (1.11e-1)" "unprognostic (2.10e-1)" "unprognostic (1.18e-1)" "unprognostic (1.27e-2)" "unprognostic (7.01e-2)" "unprognostic (1.12e-2)" "potential prognostic favorable (5.10e-5)" "unprognostic (1.53e-1)" "unprognostic (2.32e-1)" "unprognostic (8.94e-2)" "unprognostic (3.30e-2)" "unprognostic (9.46e-2)" "unprognostic (1.49e-1)" "unprognostic (1.59e-2)" "unprognostic (2.50e-1)" "unprognostic (2.17e-2)" "unprognostic (6.89e-3)" "unprognostic (4.62e-1)" "unprognostic (4.10e-2)" "unprognostic (1.29e-1)" "unprognostic (2.42e-1)" "unprognostic (1.67e-2)" "unprognostic (2.12e-1)" "unprognostic (8.78e-3)" "unprognostic (2.29e-1)" TMEM138 "HSPC196, JBTS16" ENSG00000149483 "Transmembrane protein 138" Q9NPI0 11 61361964-61377890 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adrenal cortex cells: 81.6;Rod photoreceptor cells: 134.9" "Cell type enhanced" "Detected in all" "Neuronal cells: 134.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA042373 Approved Approved "Microtubules,Primary cilium" NA Yes "Cluster 29: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 9: Non-specific - Receptor signaling" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" "Microtubules, Primary cilium" "HPA042373: " "unprognostic (2.80e-1)" "unprognostic (1.55e-3)" "unprognostic (1.90e-1)" "unprognostic (4.67e-3)" "unprognostic (9.21e-2)" "unprognostic (2.26e-1)" "unprognostic (4.19e-3)" "unprognostic (4.33e-2)" "unprognostic (3.30e-1)" "unprognostic (1.44e-1)" "potential prognostic unfavorable (9.44e-4)" "unprognostic (3.95e-2)" "unprognostic (2.32e-1)" "unprognostic (2.61e-3)" "unprognostic (5.28e-2)" "unprognostic (2.47e-1)" "unprognostic (1.48e-1)" "unprognostic (5.93e-2)" "unprognostic (1.71e-1)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (8.47e-2)" "unprognostic (2.62e-2)" "unprognostic (3.96e-1)" "unprognostic (1.72e-1)" "unprognostic (1.92e-1)" "unprognostic (2.81e-2)" "unprognostic (2.11e-1)" "unprognostic (6.83e-2)" "unprognostic (7.43e-2)" "unprognostic (1.63e-1)" TMEM175 MGC4618 ENSG00000127419 "Transmembrane protein 175" Q9BSA9 4 932387-958656 "Disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 26 "Pancreatic islets: 2632.1" "Not detected" "Not detected" HPA057160 Approved Approved "Nucleoplasm,Nuclear membrane" No No "Cluster 10: Non-specific - Membrane trafficking" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 98: Neurons - Neurotransmission & signaling" "Nucleoplasm, Nuclear membrane" "HPA057160: " "unprognostic (3.00e-1)" "unprognostic (4.86e-1)" "unprognostic (6.11e-2)" "unprognostic (3.73e-1)" "unprognostic (2.31e-1)" "unprognostic (1.78e-1)" "unprognostic (4.46e-2)" "unprognostic (1.33e-1)" "unprognostic (6.65e-2)" "unprognostic (1.41e-1)" "unprognostic (4.44e-2)" "unprognostic (6.07e-2)" "potential prognostic favorable (7.32e-4)" "unprognostic (5.41e-2)" "unprognostic (3.64e-2)" "unprognostic (8.72e-2)" "unprognostic (5.77e-2)" "unprognostic (1.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.49e-1)" "unprognostic (1.60e-3)" "potential prognostic favorable (3.16e-4)" "unprognostic (8.23e-2)" "unprognostic (1.49e-1)" "unprognostic (7.00e-3)" "unprognostic (5.20e-2)" "unprognostic (6.31e-2)" "unprognostic (6.77e-2)" "unprognostic (1.62e-1)" "unprognostic (1.58e-1)" "unprognostic (1.85e-1)" TMEM201 "Ima1, NET5, RP13-15M17.2, SAMP1" ENSG00000188807 "Transmembrane protein 201" Q5SNT2 1 9588911-9614877 "Predicted membrane proteins, Transporters" Angiogenesis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 40.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 805943.0" "Tissue enriched" "Detected in some" "pancreas: 209665.6" CAB039039 Approved Supported "Nucleoplasm,Nuclear membrane" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 37: Non-specific - mRNA processing" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 34 "Nuclear membrane" Nucleoplasm "CAB039039: " "unprognostic (1.47e-1)" "unprognostic (4.68e-2)" "unprognostic (3.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.39e-1)" "unprognostic (2.91e-1)" "unprognostic (4.08e-1)" "unprognostic (6.00e-2)" "unprognostic (1.89e-2)" "unprognostic (1.03e-1)" "unprognostic (1.28e-1)" "unprognostic (2.16e-1)" "validated prognostic unfavorable (2.48e-7)" "validated prognostic unfavorable (2.09e-4)" "unprognostic (2.21e-1)" "unprognostic (7.99e-2)" "unprognostic (2.42e-2)" "unprognostic (3.31e-2)" "unprognostic (4.31e-2)" "unprognostic (8.79e-3)" "potential prognostic favorable (5.41e-4)" "unprognostic (4.31e-1)" "unprognostic (3.37e-1)" "unprognostic (3.27e-1)" "unprognostic (1.76e-2)" "unprognostic (2.10e-1)" "unprognostic (9.49e-2)" "unprognostic (6.36e-2)" "unprognostic (7.90e-3)" "unprognostic (3.13e-1)" TMEM215 ENSG00000188133 "Transmembrane protein 215" Q68D42 9 32783540-32789201 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 7 "retina: 16.9" "Group enriched" "Detected in some" 15 "Early spermatids: 157.5;Late spermatids: 574.8;Retinal bipolar cells: 477.0" "Group enriched" "Detected in some" 86 "Neuronal cells: 477.0;Spermatogenic cell types: 574.8" "Cell type enhanced" "Detected in many" "hippocampal CA4: 13.8;medium spiny neuron: 11.6;midbrain-derived inhibitory: 32.7" "Cancer enriched" "Detected in single" 17 "Thyroid Carcinoma (TCGA): 8.0" "Region enhanced" "Detected in many" "hypothalamus: 13.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Minor Salivary Gland - Fibroblasts, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA063207 Approved Nucleoplasm,Vesicles NA NA "Cluster 42: Retina - Visual perception" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" "Nucleoplasm, Vesicles" "HPA063207: " "unprognostic (1.27e-1)" "unprognostic (2.81e-2)" TMEM217 "C6orf128, dJ355M6.2" ENSG00000172738 "Transmembrane protein 217" Q8N7C4 6 37212180-37258155 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.6;Bergmann glia: 5.4;Brain inhibitory neurons: 2.7;Choroid plexus epithelial cells: 3.6;Distal convoluted tubule cells: 4.1;Ependymal cells: 5.9;Loop of henle epithelial cells: 7.8;Oligodendrocytes: 3.4;Other brain neurons: 3.1;Papillary tip epithelial cells: 6.9;Podocytes: 5.4;Proximal tubule cells: 8.8;Renal collecting duct intercalated cells: 4.2;Renal collecting duct principal cells: 5.2;Renal connecting tubule cells: 5.6" "Cell type enhanced" "Detected in some" "Ciliated cells: 5.9;Ductal cells: 5.6;Glial cells: 5.4;Neuronal cells: 3.1;Renal nephron cells: 8.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Adrenal gland - Adrenal cortex cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045432, HPA071187" Approved Nucleoli,Cytosol NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 102: Non-specific - Mixed function" Nucleoli Cytosol "HPA045432: , HPA071187: " "unprognostic (1.06e-1)" "unprognostic (2.12e-2)" "unprognostic (3.16e-2)" "unprognostic (2.22e-2)" "unprognostic (1.83e-1)" "unprognostic (9.35e-2)" "unprognostic (2.31e-2)" "unprognostic (1.01e-1)" "unprognostic (2.65e-2)" "unprognostic (4.55e-2)" "unprognostic (9.33e-2)" "unprognostic (4.31e-2)" "unprognostic (2.30e-3)" "unprognostic (4.83e-2)" "unprognostic (3.45e-2)" "unprognostic (7.05e-2)" "potential prognostic favorable (6.17e-5)" "unprognostic (4.14e-1)" "unprognostic (4.87e-2)" "unprognostic (1.91e-1)" "unprognostic (2.05e-3)" TMEM231 "ALYE870, FLJ22167, JBTS20, MKS11, PRO1886" ENSG00000205084 "Transmembrane protein 231" Q9H6L2 16 75536741-75556289 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 38.2;fallopian tube: 69.1" "Cell type enriched" "Detected in some" 5 "Ependymal cells: 79.1" "Cell type enriched" "Detected in some" 7 "Ciliated cells: 79.1" "Cell type enriched" "Detected in many" 6 "ependymal cell: 110.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 32400604.3" "Tissue enriched" "Detected in many" "fallopian tube: 6849316.9" HPA042081 Enhanced Approved "Golgi apparatus,Vesicles,Mid piece" NA NA "Cluster 18: Non-specific - Translation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 34: Ciliated cells - Cilia assembly & function" 36 Vesicles "Golgi apparatus, Mid piece" "HPA042081: " "unprognostic (1.08e-1)" "unprognostic (9.58e-2)" "unprognostic (1.65e-1)" "unprognostic (1.06e-1)" "unprognostic (6.83e-2)" "unprognostic (3.87e-2)" "unprognostic (3.28e-1)" "unprognostic (1.56e-3)" "unprognostic (1.31e-1)" "unprognostic (5.52e-2)" "unprognostic (3.60e-1)" "unprognostic (5.52e-2)" "unprognostic (8.86e-2)" "unprognostic (1.97e-2)" "unprognostic (9.43e-2)" "unprognostic (2.44e-1)" "unprognostic (6.99e-3)" "unprognostic (2.11e-1)" "unprognostic (7.63e-2)" "unprognostic (2.56e-1)" "unprognostic (1.01e-1)" "unprognostic (3.67e-1)" "unprognostic (4.16e-1)" "unprognostic (7.77e-3)" "unprognostic (3.91e-2)" "unprognostic (3.62e-1)" "unprognostic (2.04e-1)" "unprognostic (1.78e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" TMEM237 "ALS2CR4, JBTS14" ENSG00000155755 "Transmembrane protein 237" Q96Q45 2 201620184-201643570 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cilium biogenesis/degradation" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "retina: 71.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 77.7;Breast myoepithelial cells: 102.5;Rod photoreceptor cells: 181.8" "Cell type enhanced" "Detected in many" "Neuronal cells: 181.8;Secretory gland support: 102.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 4897 "Fallopian tube cells: 489675.8" "Tissue enriched" "Detected in some" "fallopian tube: 167808.5" "HPA052596, HPA054732" Enhanced Approved "Nuclear speckles,Plasma membrane,Microtubules,Cytokinetic bridge,Primary cilium,Primary cilium transition zone" Yes NA "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 9 "Nuclear speckles, Plasma membrane, Microtubules, Primary cilium" "Cytokinetic bridge, Primary cilium transition zone" "HPA052596: , HPA054732: " "unprognostic (1.24e-1)" "unprognostic (8.96e-3)" "unprognostic (2.99e-2)" "unprognostic (1.33e-1)" "unprognostic (1.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.84e-2)" "unprognostic (8.17e-2)" "unprognostic (1.30e-1)" "unprognostic (5.23e-2)" "unprognostic (9.73e-2)" "unprognostic (7.39e-3)" "validated prognostic unfavorable (3.18e-5)" "validated prognostic unfavorable (1.55e-5)" "unprognostic (3.42e-1)" "unprognostic (3.35e-2)" "unprognostic (5.90e-2)" "unprognostic (1.11e-1)" "unprognostic (7.31e-2)" "unprognostic (3.11e-1)" "unprognostic (5.73e-2)" "unprognostic (9.20e-3)" "unprognostic (4.00e-1)" "unprognostic (2.93e-2)" "unprognostic (1.68e-3)" "unprognostic (4.08e-2)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" TMEM252 "C9orf71, MGC34760" ENSG00000181778 "Transmembrane protein 252" Q8N6L7 9 68536580-68540883 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 20.7;kidney: 33.3" "Cell type enriched" "Detected in some" 4 "Enterocytes: 56.9" "Cell type enriched" "Detected in some" 4 "Enterocytes: 56.9" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 7 "Kidney Renal Papillary Cell Carcinoma (TCGA): 136.9" "Region enhanced" "Detected in single" "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 8 "neutrophil: 4.1" "Lineage enriched" "Detected in single" 40 "granulocytes: 4.1" "Group enriched" "Detected in some" 7 "ovarian cancer: 1.0;Uterine cancer: 2.3" "Adipose subcutaneous - Smooth muscle cells, Adrenal gland - Adrenal cortex cells, Kidney - Proximal tubular cells, Prostate - Smooth muscle cells, Skin - Fibroblasts_2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045272, HPA079457" Enhanced Approved "Nuclear speckles,Plasma membrane,Primary cilium,Basal body" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 15: Kidney cancer - Membrane components" "Cluster 1: Enterocytes - Absorption and Digestion" 5 "Nuclear speckles, Plasma membrane" "Primary cilium, Basal body" "HPA045272: , HPA079457: " "unprognostic (1.82e-2)" "unprognostic (2.25e-1)" "validated prognostic favorable (1.15e-7)" "validated prognostic favorable (3.24e-4)" "unprognostic (2.80e-3)" "unprognostic (2.39e-2)" "unprognostic (6.07e-3)" "unprognostic (7.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.96e-1)" TMEM255A "FAM70A, FLJ20716" ENSG00000125355 "Transmembrane protein 255A" Q5JRV8 X 120258650-120311556 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;ovary: 16.4" "Cell type enhanced" "Detected in some" "Bergmann glia: 16.6;Corticotrophs: 35.3;Fibro-adipogenic progenitors: 14.3;Mesothelial cells: 14.6;Microglia: 12.8;Myosatellite cells: 15.7;Oligodendrocyte progenitor cells: 48.2;Other brain neurons: 37.2;Pituitary stem cells: 30.3;Renal collecting duct intercalated cells: 29.0;Retinal amacrine cells: 26.2;Schwann cells: 17.6" "Cell type enhanced" "Detected in many" "Ductal cells: 29.0;Glial cells: 48.2;Neuronal cells: 37.2;Pituitary endocrine cells: 35.3;Stem cells: 30.3" "Cell type enhanced" "Detected in many" "LAMP5-LHX6 and Chandelier: 105.4;oligodendrocyte precursor cell: 55.1" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 40.9;Kidney Chromophobe (TCGA): 103.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.8" "Lineage enriched" "Detected in single" 9 "T-cells: 2.8" "Cancer enhanced" "Detected in many" "Myeloma: 13.1;skin cancer: 11.7" "Minor Salivary Gland - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA048470 Approved Uncertain "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 109: Neurons - Neuronal signaling" "Nucleoplasm, Nuclear bodies" "HPA048470: " "unprognostic (2.51e-2)" "unprognostic (1.21e-1)" "unprognostic (3.48e-1)" "unprognostic (1.80e-1)" "unprognostic (1.49e-1)" "unprognostic (1.12e-1)" "unprognostic (5.52e-2)" "unprognostic (1.51e-1)" "unprognostic (6.75e-2)" "unprognostic (2.25e-1)" "unprognostic (4.31e-2)" "unprognostic (1.28e-1)" "unprognostic (9.34e-2)" "unprognostic (1.19e-1)" "unprognostic (1.91e-1)" "unprognostic (1.14e-2)" "unprognostic (2.41e-1)" "unprognostic (1.34e-1)" "unprognostic (2.25e-1)" "unprognostic (7.83e-2)" "unprognostic (3.80e-1)" "unprognostic (3.01e-2)" TMEM256 "C17orf61, MGC40107" ENSG00000205544 "Transmembrane protein 256" Q8N2U0 17 7402975-7404097 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 660.1;Epididymal efferent duct absorptive cells: 256.5;Epididymal principal cells: 226.1;Gastric chief cells: 298.1;Hepatocytes: 355.5;Oocytes: 257.9;Parietal cells: 401.3" "Cell type enhanced" "Detected in many" "Enterocytes: 660.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 17272735.6" "Low tissue specificity" "Detected in many" HPA062732 Approved Vesicles NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 1: Enterocytes - Absorption and Digestion" Vesicles "HPA062732: " "unprognostic (2.20e-3)" "unprognostic (7.00e-2)" "unprognostic (8.69e-2)" "unprognostic (2.16e-1)" "unprognostic (1.42e-2)" "unprognostic (5.21e-2)" "unprognostic (2.54e-1)" "unprognostic (2.03e-3)" "unprognostic (6.50e-2)" "unprognostic (2.07e-1)" "unprognostic (9.80e-2)" "unprognostic (1.05e-3)" "unprognostic (2.10e-2)" "unprognostic (2.90e-2)" "unprognostic (2.09e-1)" "unprognostic (2.30e-1)" "unprognostic (2.52e-1)" "unprognostic (1.67e-2)" "unprognostic (5.79e-2)" "unprognostic (6.28e-2)" "unprognostic (4.58e-2)" "unprognostic (1.39e-1)" "unprognostic (1.13e-1)" "unprognostic (1.20e-1)" "unprognostic (6.05e-2)" "unprognostic (2.17e-2)" "unprognostic (1.96e-1)" "unprognostic (1.65e-1)" "unprognostic (9.46e-2)" TMEM270 "MGC26719, WBSCR28" ENSG00000175877 "Transmembrane protein 270" Q6UE05 7 73861159-73865890 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 220 "testis: 74.6" "Group enriched" "Detected in some" 96 "Early spermatids: 1090.5;Late primary spermatocytes: 310.6;Late spermatids: 387.4" "Cell type enriched" "Detected in some" 177 "Spermatogenic cell types: 1090.5" "Cell type enriched" "Detected in single" 5 "ependymal cell: 3.6" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077196 Approved Vesicles NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 27: Breast cancer - Unknown function" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Vesicles "HPA077196: " "unprognostic (1.80e-2)" "unprognostic (3.58e-1)" "potential prognostic unfavorable (8.36e-4)" TMEM37 "PR, PR1" ENSG00000171227 "Transmembrane protein 37" Q8WXS4 2 119429901-119438504 "Predicted intracellular proteins, Predicted membrane proteins" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 94.3;liver: 94.5;parathyroid gland: 117.1" "Cell type enhanced" "Detected in many" "Colonocytes: 127.1;Decidual stromal cells: 457.9;Enterocytes: 545.0;Esophageal apical cells: 121.4;Hepatocytes: 218.8;Hofbauer cells: 92.1;Kupffer cells: 164.0;Müller glia: 124.7;Syncytiotrophoblasts: 154.1" "Cell type enhanced" "Detected in many" "Enterocytes: 545.0;Hepatocytes: 218.8;Stromal cells: 457.9" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 2.6;endothelial cell: 7.6;fibroblast: 4.2" "Cancer enhanced" "Detected in all" "Kidney Renal Clear Cell Carcinoma (TCGA): 165.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "liver cancer: 32.2" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Skeletal muscle - Fibroblasts, Spleen - Macrophages, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA053794, HPA076947" Enhanced Approved "Golgi apparatus" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 76: Non-specific - Metabolism" "Cluster 38: Sub-cortical - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" "Golgi apparatus" "HPA053794: , HPA076947: " "unprognostic (6.57e-2)" "unprognostic (4.06e-2)" "unprognostic (2.56e-3)" "unprognostic (4.62e-2)" "unprognostic (2.29e-1)" "unprognostic (1.88e-1)" "unprognostic (6.49e-2)" "unprognostic (7.57e-2)" "unprognostic (1.60e-1)" "unprognostic (8.30e-2)" "validated prognostic favorable (7.25e-10)" "validated prognostic favorable (2.23e-4)" "unprognostic (1.12e-1)" "unprognostic (8.79e-2)" "unprognostic (3.33e-3)" "unprognostic (1.04e-1)" "unprognostic (4.70e-2)" "unprognostic (9.29e-2)" "unprognostic (4.06e-1)" "unprognostic (1.11e-1)" "unprognostic (1.54e-1)" "unprognostic (1.08e-1)" "unprognostic (8.72e-2)" "unprognostic (6.79e-2)" "unprognostic (1.01e-1)" "unprognostic (1.96e-1)" "unprognostic (1.49e-1)" "unprognostic (7.46e-3)" "unprognostic (4.62e-2)" "unprognostic (1.66e-1)" "unprognostic (1.56e-1)" TMEM40 FLJ11036 ENSG00000088726 "Transmembrane protein 40" Q8WWA1 3 12733528-12769457 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "cervix: 55.3;esophagus: 213.6;skin 1: 61.8;vagina: 77.3" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 5067.0;Esophageal suprabasal cells: 1124.4;Megakaryocytes: 364.7;Platelets: 2578.0;Suprabasal keratinocytes: 487.9;Syncytiotrophoblasts: 1099.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 5067.0;Platelets: 2578.0;Suprabasal cells: 1124.4;Trophoblast cells: 1099.7" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bladder Urothelial Carcinoma (TCGA): 53.7;Head and Neck Squamous Cell Carcinoma (TCGA): 70.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.0" "Lineage enriched" "Detected in single" 7 "granulocytes: 6.0" "Cancer enhanced" "Detected in many" "Gallbladder cancer: 63.9;head and neck cancer: 46.8" "Heart muscle - Cardiomyocytes, Prostate - Urothelial cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 7528 "Keratinocytes: 752844.6" "Group enriched" "Detected in some" "bone marrow: 149690.1;intestine: 194171.4;lymphoid tissue: 51853.4" "HPA044165, HPA073122" Enhanced Approved "Plasma membrane,Cytosol" NA NA 1100000 "Cluster 21: Neutrophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 9: Non-specific - Receptor signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 3 "Plasma membrane" Cytosol "HPA044165: , HPA073122: " "unprognostic (2.37e-1)" "unprognostic (8.59e-3)" "unprognostic (3.80e-1)" "unprognostic (1.67e-2)" "unprognostic (1.04e-1)" "unprognostic (1.99e-1)" "potential prognostic unfavorable (3.61e-4)" "unprognostic (1.24e-1)" "unprognostic (3.64e-1)" "unprognostic (1.65e-2)" "unprognostic (5.69e-2)" "unprognostic (1.31e-3)" "potential prognostic unfavorable (6.31e-5)" "unprognostic (3.38e-1)" "unprognostic (3.31e-2)" "unprognostic (1.84e-1)" "unprognostic (2.45e-1)" "unprognostic (1.77e-1)" "unprognostic (3.93e-2)" TMEM45B "BC016153, FLJ40787" ENSG00000151715 "Transmembrane protein 45B" Q96B21 11 129815848-129860003 "Predicted membrane proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 64.1;intestine: 128.3" "Cell type enhanced" "Detected in many" "Colonocytes: 406.1;Enteric transient amplifying cells: 185.3;Enterocytes: 465.8;Esophageal apical cells: 1167.6;Esophageal suprabasal cells: 263.8;Prostatic club cells: 185.9;Respiratory ciliated cells: 167.5;Tuft cells: 230.6;Urothelial cells: 304.0" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 1167.6;Enterocytes: 465.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 22.0;endothelial cell: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "memory CD4 T-cell: 3.1;naive CD4 T-cell: 3.6;neutrophil: 11.8" "Group enriched" "Detected in many" 14 "granulocytes: 11.8;T-cells: 3.6" "Cancer enhanced" "Detected in many" "colorectal cancer: 56.4;prostate cancer: 85.3" "Adrenal gland - Adrenal medulla cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Colon - Colon enterocytes, Lung - Alveolar cells type 2, Prostate - Urothelial cells, Spleen - Neutrophils_2, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Collecting ducts: 963024.5" "Not detected" "Not detected" "HPA015474, HPA015878" Approved Approved Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 77: Intestine - Digestion" "Cluster 23: Choroid plexus - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 31 Nucleoplasm "HPA015474: , HPA015878: " "unprognostic (1.15e-1)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (3.77e-1)" "unprognostic (1.81e-2)" "unprognostic (2.79e-1)" "unprognostic (6.92e-3)" "unprognostic (9.09e-2)" "unprognostic (4.73e-2)" "unprognostic (1.86e-2)" "unprognostic (1.40e-2)" "unprognostic (6.51e-3)" "potential prognostic unfavorable (8.02e-4)" "unprognostic (3.92e-2)" "unprognostic (1.15e-1)" "unprognostic (3.82e-2)" "unprognostic (8.57e-3)" "unprognostic (2.40e-2)" "unprognostic (1.13e-1)" "unprognostic (2.74e-3)" "unprognostic (1.30e-1)" "unprognostic (1.47e-1)" "unprognostic (3.07e-1)" "unprognostic (1.36e-1)" "unprognostic (8.34e-3)" "unprognostic (1.11e-1)" "unprognostic (4.25e-2)" "unprognostic (4.05e-2)" "unprognostic (3.38e-1)" "unprognostic (1.16e-1)" "unprognostic (1.57e-1)" TMEM53 "FLJ22353, NET4" ENSG00000126106 "Transmembrane protein 53" Q6P2H8 1 44635238-44674481 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 56.1" "Cell type enriched" "Detected in many" 8 "Late spermatids: 1699.8" "Cell type enriched" "Detected in many" 15 "Spermatogenic cell types: 1699.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "plasmacytoid DC: 99.6" "Lineage enriched" "Detected in all" 4 "dendritic cells: 99.6" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Liver - Hepatocytes, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1067256.4;Hepatocytes: 1433358.0" "Tissue enriched" "Detected in single" 138 "liver: 13789.8" HPA021134 Approved Approved "Golgi apparatus,Focal adhesion sites" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 47: Testis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" 6 "Golgi apparatus" "Focal adhesion sites" "HPA021134: " "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "unprognostic (3.80e-1)" "unprognostic (1.78e-1)" "unprognostic (7.71e-3)" "unprognostic (1.42e-1)" "unprognostic (1.42e-2)" "unprognostic (4.18e-2)" "unprognostic (5.68e-2)" "unprognostic (5.32e-2)" "unprognostic (1.17e-1)" "unprognostic (1.86e-1)" "unprognostic (2.43e-2)" "unprognostic (2.69e-3)" "unprognostic (3.02e-1)" "unprognostic (1.02e-3)" "unprognostic (1.60e-2)" "unprognostic (9.97e-3)" "unprognostic (2.27e-1)" "potential prognostic favorable (6.65e-4)" "unprognostic (1.18e-3)" "unprognostic (2.24e-1)" "unprognostic (7.30e-2)" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (1.07e-1)" "unprognostic (3.92e-1)" "unprognostic (4.47e-2)" "unprognostic (2.30e-1)" "unprognostic (1.89e-2)" "unprognostic (3.61e-1)" TMEM61 ENSG00000143001 "Transmembrane protein 61" Q8N0U2 1 54980628-54992288 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 16.1;pituitary gland: 38.2;salivary gland: 18.4" "Cell type enhanced" "Detected in many" "Conjunctival goblet cells: 50.5;Corticotrophs: 70.8;Epididymal clear cells: 87.8;Goblet cells: 63.5;Pancreatic islet cells: 42.1;Respiratory ionocytes: 355.6;Salivary duct cells: 54.3;Salivary ionocytes: 219.3;Salivary myoepithelial cells: 42.3" "Cell type enriched" "Detected in many" 4 "Ionocytes: 355.6" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 9.8;lower rhombic lip: 12.7;upper rhombic lip: 6.9" "Cancer enriched" "Detected in many" 7 "Kidney Chromophobe (TCGA): 38.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "lung cancer: 3.4;pancreatic cancer: 3.6" "Adipose subcutaneous - Smooth muscle cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Corticotropes" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030614, HPA057087" Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 49: Hindbrain - Mixed function" "Cluster 2: Mucus-secreting cells - Unknown function" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 "Plasma membrane" Vesicles "HPA030614: , HPA057087: " "unprognostic (2.69e-3)" "unprognostic (2.88e-1)" "unprognostic (2.76e-3)" "unprognostic (1.05e-1)" "potential prognostic favorable (8.35e-4)" "unprognostic (2.23e-2)" "unprognostic (1.10e-1)" "unprognostic (1.69e-2)" "unprognostic (1.82e-2)" "unprognostic (2.02e-1)" "unprognostic (6.54e-2)" "unprognostic (1.40e-2)" "unprognostic (6.08e-2)" "unprognostic (1.55e-1)" "unprognostic (4.95e-3)" "unprognostic (8.24e-2)" "unprognostic (2.88e-2)" "unprognostic (5.11e-2)" "unprognostic (2.60e-3)" "unprognostic (1.78e-1)" "unprognostic (1.50e-2)" TMEM70 FLJ20533 ENSG00000175606 "Transmembrane protein 70" Q9BUB7 8 73972437-73982783 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "skeletal muscle: 95.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 137.0;Parietal cells: 185.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in some" "cerebral cortex: 2623995.7;liver: 2165843.8" "HPA023187, CAB034226" Approved Supported Nucleoplasm,Mitochondria NA Yes "Cluster 45: Eosinophils - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 16 Mitochondria Nucleoplasm "CAB034226: , HPA023187: " "unprognostic (1.83e-1)" "potential prognostic unfavorable (2.12e-4)" "unprognostic (7.64e-2)" "unprognostic (1.18e-3)" "potential prognostic favorable (2.98e-4)" "unprognostic (2.88e-1)" "unprognostic (1.54e-3)" "unprognostic (1.45e-2)" "unprognostic (5.36e-2)" "unprognostic (9.83e-2)" "unprognostic (1.52e-1)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (3.19e-1)" "unprognostic (1.97e-1)" "unprognostic (1.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.34e-2)" "unprognostic (1.16e-2)" "unprognostic (1.64e-1)" "unprognostic (2.14e-1)" "unprognostic (1.17e-1)" "unprognostic (1.95e-2)" "potential prognostic unfavorable (2.55e-5)" "unprognostic (3.03e-1)" "unprognostic (2.62e-1)" "unprognostic (1.32e-1)" "unprognostic (1.28e-2)" "unprognostic (2.23e-1)" "unprognostic (8.21e-3)" "unprognostic (1.55e-2)" "unprognostic (1.32e-1)" TMEM71 FLJ33069 ENSG00000165071 "Transmembrane protein 71" Q6P5X7 8 132685007-132760712 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 31.6;heart muscle: 34.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 326.0;Monocyte progenitors: 100.7;monocytes: 124.5;Neutrophil progenitors: 280.5;Neutrophils: 1033.9;NK-cells: 149.5;T-cells: 109.6" "Group enriched" "Detected in many" 4 "Myocytes: 326.0;Neutrophils: 1033.9" "Cell type enhanced" "Detected in some" "fibroblast: 56.2;leukocyte: 177.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 4 "cerebral cortex: 20.8" "Immune cell enhanced" "Detected in all" "neutrophil: 270.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 270.6" "Cancer enhanced" "Detected in many" "Bone cancer: 9.1;Leukemia: 8.0" "Adrenal gland - Adrenal medulla cells, Colon - Enteric glia cells, Lung - NK-cells (Lung), Spleen - Neutrophils_2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA058401, HPA070655" Uncertain Enhanced Mitochondria NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 35: Non-specific - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" Mitochondria "HPA058401: , HPA070655: " "unprognostic (1.06e-1)" "potential prognostic favorable (3.51e-4)" "unprognostic (3.59e-2)" "unprognostic (6.10e-2)" "unprognostic (2.49e-1)" "unprognostic (3.71e-3)" "unprognostic (3.43e-2)" "unprognostic (1.29e-3)" "unprognostic (1.31e-2)" "unprognostic (5.16e-2)" "unprognostic (2.40e-1)" "potential prognostic favorable (2.25e-4)" "unprognostic (3.49e-2)" "unprognostic (1.38e-3)" "unprognostic (1.12e-1)" "unprognostic (2.42e-1)" "unprognostic (9.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (1.13e-2)" "unprognostic (2.22e-1)" "unprognostic (8.95e-2)" "unprognostic (1.78e-1)" "unprognostic (2.45e-2)" "unprognostic (4.03e-2)" "unprognostic (6.92e-2)" TMEM86B MGC30208 ENSG00000180089 "Transmembrane protein 86B" Q8N661 19 55226638-55228784 "Enzymes, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 47.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 28.3;Erythrocyte progenitors: 25.0;Erythrocytes: 22.0;Foveolar cells: 20.2;Hepatocytes: 38.9;Neuroendocrine cells: 19.9;Pancreatic islet cells: 16.2;Parietal cells: 38.9" "Cell type enhanced" "Detected in many" "Ductal cells: 28.3;Erythrocytes: 25.0;Gastric glandular cells: 38.9;Hepatocytes: 38.9" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 6 "Liver Hepatocellular Carcinoma (TCGA): 30.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Stomach - Parietal cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA057689 Uncertain Uncertain Midbody,Centrosome Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 37: Neurons - Mixed function" "Cluster 18: Liver cancer - Metabolism" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 92 Centrosome Midbody "HPA057689: " "unprognostic (8.97e-2)" "unprognostic (2.21e-1)" "unprognostic (1.19e-2)" "unprognostic (1.03e-1)" "unprognostic (7.83e-2)" "unprognostic (4.81e-2)" "unprognostic (4.02e-1)" "unprognostic (3.04e-1)" "unprognostic (1.60e-1)" "unprognostic (6.18e-2)" "potential prognostic unfavorable (2.00e-6)" "unprognostic (8.30e-2)" "unprognostic (1.03e-1)" "unprognostic (1.77e-3)" "unprognostic (8.16e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (8.19e-2)" "unprognostic (9.71e-3)" "potential prognostic favorable (2.98e-4)" "unprognostic (1.11e-2)" "unprognostic (2.87e-1)" "unprognostic (9.14e-2)" "unprognostic (4.44e-3)" "unprognostic (2.63e-1)" "unprognostic (3.89e-2)" "unprognostic (7.95e-2)" "unprognostic (7.54e-2)" TMEM89 ENSG00000183396 "Transmembrane protein 89" A2RUT3 3 48620759-48621769 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 28.3" "Group enriched" "Detected in some" 167 "Early spermatids: 306.3;Late primary spermatocytes: 268.8;Late spermatids: 312.5" "Cell type enriched" "Detected in some" 176 "Spermatogenic cell types: 312.5" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA053577 Uncertain Approved "Perinuclear theca" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 15: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 "Perinuclear theca" "HPA053577: " "unprognostic (1.38e-1)" "unprognostic (7.78e-3)" TMEM9 TMEM9A ENSG00000116857 "Transmembrane protein 9" Q9P0T7 1 201134772-201171574 "Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 212.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 212.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Breast - Breast glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glomeruli: 12910857.0;Proximal tubules: 3714556.1" "Group enriched" "Detected in many" "cerebral cortex: 329309.9;liver: 1157526.2;lung: 449041.5" HPA008483 Approved "Vesicles,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 45: Non-specific - Nuclear processes" "Cluster 94: Gonadal somatic cells - Mixed function" 107 Vesicles "Microtubules, Cytokinetic bridge, Mitotic spindle" "HPA008483: " "unprognostic (1.19e-1)" "unprognostic (3.21e-2)" "unprognostic (3.26e-2)" "unprognostic (1.29e-3)" "unprognostic (3.54e-1)" "unprognostic (1.41e-1)" "unprognostic (1.54e-1)" "unprognostic (3.30e-1)" "potential prognostic unfavorable (5.28e-4)" "potential prognostic unfavorable (1.09e-5)" "unprognostic (1.41e-2)" "unprognostic (8.71e-2)" "unprognostic (3.79e-2)" "unprognostic (1.89e-3)" "unprognostic (1.72e-2)" "unprognostic (3.49e-1)" "unprognostic (2.68e-1)" "unprognostic (6.17e-2)" "unprognostic (1.97e-1)" "unprognostic (1.28e-1)" "unprognostic (5.50e-2)" "unprognostic (8.71e-2)" "unprognostic (2.69e-1)" "unprognostic (1.30e-1)" "unprognostic (2.84e-2)" "unprognostic (1.78e-1)" "unprognostic (1.14e-2)" "unprognostic (7.32e-2)" "unprognostic (2.05e-1)" "unprognostic (8.85e-2)" "unprognostic (1.61e-2)" TMLHE "BBOX2, FLJ10727, TMLH, XAP130" ENSG00000185973 "Trimethyllysine hydroxylase, epsilon" Q9NVH6 X 155489011-155719098 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carnitine biosynthesis" "Dioxygenase, Oxidoreductase" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 218.0;Cardiomyocytes: 352.0;Myonuclei: 875.2" "Cell type enriched" "Detected in many" 4 "Myocytes: 875.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubules: 45380410.2" "Tissue enhanced" "Detected in all" "heart muscle: 21478963.0" "HPA034589, HPA040331" Approved Supported Mitochondria NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 29 Mitochondria "HPA034589: , HPA040331: " "unprognostic (1.38e-1)" "unprognostic (5.31e-2)" "unprognostic (2.24e-1)" "unprognostic (1.93e-1)" "unprognostic (1.06e-1)" "unprognostic (1.15e-1)" "unprognostic (3.43e-3)" "unprognostic (3.92e-2)" "unprognostic (2.93e-2)" "unprognostic (2.56e-2)" "potential prognostic favorable (3.39e-7)" "unprognostic (7.37e-3)" "unprognostic (2.63e-1)" "unprognostic (8.50e-2)" "unprognostic (1.18e-1)" "unprognostic (8.64e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (3.53e-2)" "unprognostic (1.06e-1)" "unprognostic (9.68e-2)" "unprognostic (2.41e-3)" "unprognostic (4.78e-2)" "unprognostic (7.10e-2)" "unprognostic (3.87e-3)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.85e-1)" "unprognostic (1.14e-1)" "unprognostic (2.18e-1)" "unprognostic (4.55e-1)" TMPO "LAP2, LEMD4, TP" ENSG00000120802 Thymopoietin "P42166, P42167" 12 98515579-98550351 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" DNA-binding Cardiomyopathy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 130.2" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 360.6;Megakaryocyte progenitors: 282.7;Monocyte progenitors: 510.5" "Cell type enhanced" "Detected in all" "Erythrocytes: 360.6;Mononuclear phagocytes: 510.5" "Cell type enhanced" "Detected in all" "endothelial cell: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Endothelial cells, Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia" "Cell type enhanced" "Detected in many" "Granulosa cells: 270345037.5" "Tissue enhanced" "Detected in many" "bone marrow: 44611599.1" "HPA008150, CAB009847, HPA070805" Enhanced Enhanced "Nuclear membrane" NA Yes 180000 "Cluster 33: Non-specific - ATP binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 105 "Nuclear membrane" "CAB009847: , HPA008150: , HPA070805: " "unprognostic (2.74e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (2.34e-1)" "unprognostic (2.18e-2)" "unprognostic (3.43e-2)" "unprognostic (7.48e-2)" "unprognostic (2.53e-2)" "unprognostic (4.95e-3)" "potential prognostic unfavorable (4.12e-5)" "unprognostic (5.01e-3)" "unprognostic (6.12e-2)" "unprognostic (3.24e-3)" "unprognostic (5.70e-3)" "unprognostic (1.45e-3)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (7.95e-3)" "unprognostic (2.36e-3)" "unprognostic (1.50e-2)" "unprognostic (6.30e-2)" "unprognostic (1.56e-2)" "unprognostic (1.25e-1)" "unprognostic (1.66e-1)" "unprognostic (5.84e-2)" "unprognostic (1.12e-2)" "unprognostic (6.97e-2)" "unprognostic (6.05e-3)" "unprognostic (4.59e-2)" "unprognostic (3.56e-1)" "unprognostic (3.81e-2)" "unprognostic (1.53e-1)" TMPPE FLJ45032 ENSG00000188167 "Transmembrane protein with metallophosphoesterase domain" Q6ZT21 3 33090421-33097146 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "blood vessel: 583243.2;lung: 900079.7;lymphoid tissue: 442005.6" HPA027019 Approved Approved Nucleoplasm,Mitochondria Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 40: Non-specific - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 68: Foveolar cells - Mucosal defense" 30 "Nucleoplasm, Mitochondria" "HPA027019: " "unprognostic (2.69e-1)" "unprognostic (3.97e-2)" "unprognostic (1.39e-1)" "unprognostic (3.90e-2)" "unprognostic (2.13e-1)" "unprognostic (8.80e-3)" "unprognostic (7.12e-3)" "unprognostic (4.75e-1)" "unprognostic (3.67e-2)" "unprognostic (1.86e-1)" "unprognostic (1.73e-1)" "unprognostic (2.92e-1)" "unprognostic (1.84e-1)" "unprognostic (2.17e-1)" "unprognostic (5.84e-2)" "unprognostic (1.87e-1)" "unprognostic (1.34e-1)" TMPRSS11E "DESC1, TMPRSS11E2" ENSG00000087128 "Transmembrane serine protease 11E" Q9UL52 4 68447463-68497604 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 115.7;esophagus: 210.0;vagina: 156.3" "Group enriched" "Detected in some" 7 "Esophageal apical cells: 676.3;Salivary ionocytes: 330.8" "Group enriched" "Detected in some" 20 "Apical squamous epithelial cells: 676.3;Ionocytes: 330.8" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 26.4;Head and Neck Squamous Cell Carcinoma (TCGA): 30.0;Kidney Chromophobe (TCGA): 26.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bladder cancer: 8.2" "Minor Salivary Gland - Minor salivary gland basal cells, Skin - Outer root sheath cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 10524 "Large ducts: 1052403.5" "Not detected" "Not detected" "HPA043816, HPA051062" Uncertain Approved "Golgi apparatus" "Secreted in other tissues" Enzyme NA NA "Cluster 81: Squamous epithelium - Keratinization" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 2 "Golgi apparatus" "HPA043816: , HPA051062: " "unprognostic (1.01e-1)" "unprognostic (1.92e-2)" "unprognostic (7.90e-2)" "unprognostic (1.29e-1)" "unprognostic (1.97e-1)" "unprognostic (1.98e-2)" "potential prognostic unfavorable (4.65e-5)" "unprognostic (5.55e-3)" "unprognostic (1.64e-1)" "unprognostic (2.77e-1)" "potential prognostic unfavorable (2.00e-8)" "unprognostic (6.28e-2)" "unprognostic (9.24e-2)" "unprognostic (9.52e-2)" "unprognostic (2.96e-1)" TMTC2 DKFZp762A217 ENSG00000179104 "Transmembrane O-mannosyltransferase targeting cadherins 2" Q8N394 12 82686880-83134870 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 840.2;Oligodendrocytes: 2383.5;Renal collecting duct principal cells: 856.0;Renal connecting tubule cells: 1201.9;Retinal bipolar cells: 779.1" "Cell type enhanced" "Detected in many" "Ductal cells: 1201.9;Glial cells: 2383.5" "Cell type enhanced" "Detected in all" "oligodendrocyte: 3223.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "skin cancer: 27.8" "Skeletal muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 219514.9;Fallopian tube cells: 403903.9;Pancreatic islets: 271135.8" "Not detected" "Not detected" "HPA026954, HPA026955" Uncertain Approved "Plasma membrane,Actin filaments" No No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 69: Skin cancer - ECM organization" "Cluster 80: Oligodendrocytes - Myelination" 5 "Plasma membrane" "Actin filaments" "HPA026954: , HPA026955: " "unprognostic (4.64e-2)" "unprognostic (1.42e-1)" "unprognostic (2.72e-1)" "unprognostic (1.37e-1)" "unprognostic (9.67e-2)" "unprognostic (4.52e-2)" "unprognostic (4.59e-2)" "unprognostic (4.15e-2)" "unprognostic (5.09e-2)" "unprognostic (5.97e-2)" "validated prognostic favorable (1.27e-9)" "validated prognostic favorable (2.41e-4)" "unprognostic (5.38e-3)" "unprognostic (3.03e-1)" "unprognostic (1.99e-1)" "unprognostic (3.41e-1)" "unprognostic (6.20e-2)" "unprognostic (6.59e-2)" "unprognostic (2.62e-2)" "unprognostic (1.75e-3)" "unprognostic (3.07e-3)" "unprognostic (5.19e-2)" "unprognostic (1.18e-1)" "unprognostic (2.73e-2)" "unprognostic (1.19e-1)" "unprognostic (1.59e-1)" "unprognostic (7.68e-2)" "unprognostic (4.68e-2)" "unprognostic (7.19e-3)" "unprognostic (8.49e-3)" TNFAIP8 "GG2-1, MDC-3.13, SCC-S2" ENSG00000145779 "TNF alpha induced protein 8" O95379 5 119268692-119399688 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 110.1" "Cell type enhanced" "Detected in many" "B-cells: 549.3;Choroid plexus epithelial cells: 460.6;monocytes: 665.4;Neutrophil progenitors: 2117.5;Neutrophils: 732.2;Pancreatic acinar cells: 1068.8;Syncytiotrophoblasts: 669.0" "Cell type enhanced" "Detected in many" "Acinar cells: 1068.8;Neutrophils: 2117.5" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 456.5;leukocyte: 654.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 126.8" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adrenal gland - Macrophages, Breast - Adipocytes (Breast), Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 3130467.0;B-cells: 3266607.4" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2655914.6" "HPA054434, HPA057089" Uncertain Enhanced Nucleoplasm No Yes 110000 "Cluster 22: Eosinophils - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 12: Non-specific - Vasculature" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 10 Nucleoplasm "HPA054434: , HPA057089: " "unprognostic (7.51e-2)" "unprognostic (4.05e-2)" "unprognostic (7.00e-3)" "unprognostic (2.38e-1)" "unprognostic (2.52e-1)" "unprognostic (1.71e-1)" "unprognostic (2.85e-2)" "unprognostic (7.80e-2)" "unprognostic (5.56e-2)" "unprognostic (1.10e-2)" "potential prognostic favorable (3.99e-5)" "unprognostic (6.34e-3)" "unprognostic (1.81e-1)" "unprognostic (2.05e-2)" "unprognostic (3.16e-1)" "unprognostic (1.29e-1)" "unprognostic (7.86e-2)" "unprognostic (3.90e-2)" "unprognostic (2.77e-1)" "unprognostic (1.14e-1)" "unprognostic (1.25e-1)" "unprognostic (2.96e-2)" "unprognostic (6.07e-2)" "unprognostic (1.37e-1)" "unprognostic (7.35e-2)" "unprognostic (1.51e-1)" "unprognostic (3.15e-1)" "unprognostic (1.49e-2)" "unprognostic (4.35e-3)" "unprognostic (6.78e-3)" "unprognostic (1.79e-1)" TNFAIP8L3 FLJ41287 ENSG00000183578 "TNF alpha induced protein 8 like 3" Q5GJ75 15 51056598-51105276 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 77.7;fallopian tube: 53.7;smooth muscle: 79.2" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 168.5;Esophageal apical cells: 89.8;Fallopian tube ciliated cells: 33.0;Hepatic stellate cells: 25.8;Lymphatic endothelial cells: 62.6;Smooth muscle cells: 102.0;Thymic myoid cells: 32.6;Vascular smooth muscle cells: 30.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 89.8;Endothelial cells: 62.6;Smooth muscle cells: 102.0;Spermatogenic cell types: 168.5" "Cell type enhanced" "Detected in many" "CGE interneuron: 56.2;hippocampal CA4: 64.3;LAMP5-LHX6 and Chandelier: 44.4" "Cancer enriched" "Detected in all" 5 "Kidney Chromophobe (TCGA): 53.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bile duct cancer: 7.3" "Adipose subcutaneous - Smooth muscle cells, Prostate - Fibroblasts, Skin - Keratinocyte (granular), Spleen - Fibroblasts_1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 335 "Neurons: 33534.3" "Group enriched" "Detected in some" "fallopian tube: 4930064.6;lymphoid tissue: 1375768.0;ovary: 1768846.3" HPA077484 Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 75: Ovary - Mixed function" "Cluster 29: Forebrain - Mixed function" "Cluster 48: Adipocytes & Endothelial cells - Angiogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 Cytosol Nucleoplasm "HPA077484: " "unprognostic (5.29e-2)" "unprognostic (1.13e-1)" "unprognostic (3.96e-2)" "unprognostic (6.08e-2)" "unprognostic (8.44e-3)" "unprognostic (1.42e-1)" "unprognostic (5.83e-2)" "unprognostic (2.62e-1)" "unprognostic (2.32e-2)" "unprognostic (1.79e-1)" "unprognostic (2.93e-1)" "unprognostic (6.19e-2)" "unprognostic (1.78e-2)" "unprognostic (1.16e-2)" "unprognostic (1.39e-1)" "unprognostic (2.07e-2)" "unprognostic (2.05e-2)" "unprognostic (6.36e-3)" "potential prognostic unfavorable (6.05e-4)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (1.76e-1)" "unprognostic (2.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.52e-1)" "unprognostic (1.23e-1)" "unprognostic (1.22e-1)" "unprognostic (1.47e-2)" "unprognostic (1.09e-1)" "unprognostic (5.20e-3)" "unprognostic (1.72e-1)" TNFRSF17 "BCM, BCMA, CD269, TNFRSF13A" ENSG00000048462 "TNF receptor superfamily member 17" Q02223 16 11965210-11968068 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 27.3;lymphoid tissue: 44.8;stomach 1: 23.0" "Cell type enriched" "Detected in some" 20 "Plasma cells: 566.5" "Cell type enriched" "Detected in some" 20 "Plasma cells: 566.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 63 "memory B-cell: 125.4;naive B-cell: 109.1;plasmacytoid DC: 103.5" "Group enriched" "Detected in many" 64 "B-cells: 125.4;dendritic cells: 103.5" "Cancer enriched" "Detected in some" 9 "Myeloma: 608.0" "Adipose visceral - Plasma cells, Breast - Plasma cells, Liver - Plasma cells, Lung - Plasma cells, Minor Salivary Gland - Plasma cells, Pancreas - Plasma cells, Prostate - Plasma cells, Stomach - Plasma cells, Testis - Early spermatids, Thyroid gland - Plasma cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 712 "intestine: 71160.0" HPA010569 Approved "Golgi apparatus,Mitotic spindle" Yes NA 1300000 "Cluster 23: B-cells - Immunoglobulins" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 67: Plasma cells - Plasma cell differentiation" 4 "Golgi apparatus" "Mitotic spindle" "HPA010569: " "unprognostic (2.60e-1)" "potential prognostic favorable (4.93e-6)" "unprognostic (2.36e-1)" "unprognostic (1.52e-2)" "unprognostic (2.36e-2)" "unprognostic (7.16e-2)" "potential prognostic favorable (2.70e-6)" "unprognostic (3.19e-3)" "unprognostic (1.48e-1)" "potential prognostic unfavorable (1.56e-4)" "unprognostic (6.38e-3)" "unprognostic (9.62e-3)" "unprognostic (2.80e-1)" "unprognostic (8.38e-2)" "unprognostic (1.30e-2)" "unprognostic (3.65e-1)" "unprognostic (4.26e-3)" "unprognostic (4.10e-1)" "unprognostic (9.75e-2)" "unprognostic (1.45e-1)" "unprognostic (1.65e-1)" "unprognostic (2.65e-2)" "unprognostic (1.19e-1)" TNFRSF19 "TAJ, TAJ-alpha, TRADE, TROY" ENSG00000127863 "TNF receptor superfamily member 19" Q9NS68 13 23570370-23676104 "Plasma proteins, Predicted membrane proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 52.1;skin 1: 101.5" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 158.9;Distal convoluted tubule cells: 155.5;Lacrimal acinar cells: 331.5;Pituicytes/FSCs: 228.1;Prostatic glandular cells: 252.6;Respiratory ciliated cells: 236.9;Salivary acinar cells: 584.5" "Cell type enhanced" "Detected in many" "Acinar cells: 584.5;Ciliated cells: 236.9;Glandular cells: 252.6;Glial cells: 228.1" "Cell type enriched" "Detected in many" 4 "fibroblast: 391.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Rhabdoid: 54.7;skin cancer: 48.0" "Adrenal gland - Adrenal cortex cells, Colon - Enteric glia cells, Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Undifferentiated cells (Pituitary gland), Skeletal muscle - Fibroblasts, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA010135 Approved "Nucleoplasm,Golgi apparatus" No No 8000 "Cluster 16: Non-specific - Cell proliferation" "Cluster 37: Skin - Keratinization" "Cluster 39: Astrocytes - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 4 "Golgi apparatus" Nucleoplasm "HPA010135: " "unprognostic (2.78e-2)" "unprognostic (1.12e-1)" "unprognostic (1.15e-1)" "unprognostic (1.21e-1)" "unprognostic (3.51e-2)" "unprognostic (7.40e-2)" "unprognostic (1.49e-1)" "unprognostic (3.82e-2)" "unprognostic (9.87e-3)" "unprognostic (1.85e-1)" "potential prognostic favorable (5.39e-9)" "unprognostic (5.40e-3)" "unprognostic (4.38e-3)" "unprognostic (8.09e-2)" "unprognostic (5.21e-2)" "potential prognostic favorable (2.09e-4)" "unprognostic (6.18e-2)" "unprognostic (2.27e-1)" "unprognostic (2.36e-1)" "unprognostic (5.13e-1)" "unprognostic (1.21e-2)" "unprognostic (4.94e-2)" "unprognostic (1.18e-1)" "unprognostic (9.77e-2)" "unprognostic (3.29e-2)" "unprognostic (1.74e-1)" "unprognostic (3.26e-1)" "unprognostic (2.28e-2)" "unprognostic (4.54e-2)" "unprognostic (2.11e-3)" "unprognostic (8.55e-2)" TNFRSF21 "CD358, DR6" ENSG00000146072 "TNF receptor superfamily member 21" O75509 6 47231532-47309905 "CD markers, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Host-virus interaction, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 108.8;urinary bladder: 138.2" "Cell type enhanced" "Detected in many" "Kupffer cells: 236.8;Ocular epithelial cells: 323.3;Papillary tip epithelial cells: 358.7;Prostatic club cells: 338.6;Syncytiotrophoblasts: 274.7;Urothelial cells: 982.2" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 982.2" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 280.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 35 "plasmacytoid DC: 69.3" "Lineage enriched" "Detected in single" 302 "dendritic cells: 69.3" "Low cancer specificity" "Detected in many" "Prostate - Urothelial cells, Spleen - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 605459.0;Microglia and Neuropil: 456113.2" "Tissue enriched" "Detected in some" "cerebral cortex: 1013386.6" "HPA006746, CAB009805" Approved Supported "Plasma membrane,Cytosol" NA NA 350000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 4 "Plasma membrane, Cytosol" "CAB009805: , HPA006746: " "unprognostic (1.06e-1)" "unprognostic (7.93e-3)" "unprognostic (3.92e-1)" "unprognostic (5.90e-2)" "unprognostic (1.04e-1)" "unprognostic (1.22e-1)" "unprognostic (2.89e-1)" "unprognostic (6.99e-2)" "unprognostic (7.14e-2)" "unprognostic (1.92e-2)" "potential prognostic favorable (1.79e-7)" "unprognostic (4.11e-2)" "unprognostic (7.09e-2)" "unprognostic (1.33e-2)" "unprognostic (1.16e-2)" "unprognostic (8.33e-2)" "unprognostic (2.84e-2)" "unprognostic (2.55e-1)" "unprognostic (2.88e-2)" "unprognostic (2.58e-1)" "potential prognostic unfavorable (1.66e-4)" "unprognostic (2.27e-3)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (3.52e-1)" "unprognostic (1.98e-1)" "unprognostic (2.48e-2)" "unprognostic (5.00e-2)" "unprognostic (2.47e-1)" "unprognostic (1.96e-1)" "unprognostic (2.04e-2)" TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.1" "Cell type enhanced" "Detected in many" "Epicardial cells: 100.1;Late spermatids: 13.4;Mast cells: 13.9;Mesothelial cells: 36.3;monocytes: 16.8;Neutrophils: 20.2;Podocytes: 12.9" "Cell type enriched" "Detected in many" 4 "Barrier epithelial cells: 100.1" "Cell type enhanced" "Detected in some" "leukocyte: 6.9;medium spiny neuron: 5.9" "Cancer enriched" "Detected in some" 10 "Testicular Germ Cell Tumor (TCGA): 11.6" "Group enriched" "Detected in some" 4 "basal ganglia: 4.8;thalamus: 1.5" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 97.0" "Lineage enriched" "Detected in many" 5 "monocytes: 97.0" "Cancer enriched" "Detected in some" 7 "lymphoma: 49.3" "Adipose subcutaneous - Endothelial cells, Breast - Endothelial cells, Colon - Endothelial cells, Minor Salivary Gland - Endothelial cells" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 33: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 83: Epicardial mesothelial cells - Basic cellular functions" 6 "Plasma membrane" "CAB000016: , HPA014823: , HPA032081: , HPA032082: " "potential prognostic favorable (9.62e-4)" "unprognostic (1.65e-2)" "unprognostic (6.89e-2)" TNFSF12 "APO3L, DR3LG, TWEAK" ENSG00000239697 "TNF superfamily member 12" O43508 17 7548508-7557890 "Predicted intracellular proteins, Predicted secreted proteins" "Angiogenesis, Apoptosis, Differentiation" "Cytokine, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.9;Bergmann glia: 21.9;Brain excitatory neurons: 12.2;Brain inhibitory neurons: 9.9;Cardiomyocytes: 4.5;Ependymal cells: 7.3;Microglia: 20.7;Oligodendrocyte progenitor cells: 14.3;Other brain neurons: 10.3;Pericytes: 5.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 7.3;Glial cells: 21.9;Neuronal cells: 12.2" "Cell type enhanced" "Detected in all" "pericyte: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 644 "Smooth muscle cells: 64433.8" "Tissue enriched" "Detected in single" 4161 "blood vessel: 416065.5" "HPA035984, HPA052967" Uncertain Approved Vesicles "Secreted to blood" Cytokine NA NA 853000 110000 "Cluster 33: Non-specific - ATP binding" "Cluster 74: Non-specific - Signal transduction" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 22: Non-specific - Basic cellular functions" 6 Vesicles "HPA035984: , HPA052967: " "unprognostic (3.18e-2)" "unprognostic (7.78e-2)" "unprognostic (5.15e-1)" "unprognostic (3.53e-1)" "unprognostic (4.22e-2)" "unprognostic (1.72e-1)" "unprognostic (1.48e-3)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (3.47e-2)" "unprognostic (4.92e-2)" "potential prognostic favorable (1.58e-4)" "unprognostic (2.68e-3)" "potential prognostic favorable (2.44e-4)" "unprognostic (3.76e-2)" "unprognostic (5.06e-3)" "unprognostic (1.51e-2)" "unprognostic (2.47e-1)" "unprognostic (2.15e-2)" "unprognostic (1.35e-1)" "unprognostic (1.25e-1)" "unprognostic (3.76e-2)" "unprognostic (3.88e-2)" "unprognostic (1.16e-1)" "unprognostic (1.37e-1)" "unprognostic (6.05e-2)" "unprognostic (4.86e-2)" "unprognostic (3.05e-1)" "unprognostic (3.65e-2)" "unprognostic (5.64e-3)" "unprognostic (2.19e-1)" "unprognostic (1.67e-1)" TNFSF12-TNFSF13 TWE-PRIL ENSG00000248871 "TNFSF12-TNFSF13 readthrough" 17 7549099-7561601 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.3" "Cell type enhanced" "Detected in single" "Gastric chief cells: 1.1" "Cell type enhanced" "Detected in single" "Gastric glandular cells: 1.1" "Cancer enhanced" "Detected in many" "Kidney Renal Papillary Cell Carcinoma (TCGA): 13.4" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "eosinophil: 7.1" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA004863, HPA035984, HPA052967" Uncertain Approved Vesicles NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Vesicles "HPA004863: , HPA035984: , HPA052967: " "unprognostic (2.29e-1)" "unprognostic (2.67e-2)" "unprognostic (1.19e-2)" "unprognostic (1.53e-3)" "unprognostic (7.36e-3)" "unprognostic (2.68e-1)" "unprognostic (2.79e-1)" "potential prognostic unfavorable (2.16e-4)" "unprognostic (7.15e-2)" "unprognostic (6.98e-2)" "unprognostic (4.59e-2)" "unprognostic (3.20e-1)" "unprognostic (2.38e-1)" "unprognostic (4.06e-1)" "unprognostic (6.61e-2)" "unprognostic (1.10e-1)" "unprognostic (1.41e-1)" "unprognostic (5.01e-3)" "unprognostic (1.02e-1)" "unprognostic (1.26e-1)" "unprognostic (5.03e-2)" "unprognostic (1.95e-1)" TNIP2 "ABIN-2, FLIP1, KLIP, MGC4289" ENSG00000168884 "TNFAIP3 interacting protein 2" Q8NFZ5 4 2741648-2756342 "Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Enterocytes: 158.9;Extravillous trophoblasts: 138.2;Syncytiotrophoblasts: 120.3" "Cell type enhanced" "Detected in all" "Enterocytes: 158.9" "Cell type enhanced" "Detected in many" "pericyte: 23.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 7850355.8" "Group enriched" "Detected in many" "bone marrow: 4325773.5;lymphoid tissue: 5771140.8" "CAB020818, HPA049886, HPA063197" Supported Enhanced Nucleoplasm,Cytosol NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 18: Non-specific - Mixed function" "Cluster 55: Lymphoma - Immune response" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" 72 Nucleoplasm Cytosol "CAB020818: , HPA049886: , HPA063197: " "unprognostic (1.94e-1)" "unprognostic (2.31e-1)" "unprognostic (8.76e-3)" "unprognostic (1.95e-1)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (2.73e-1)" "potential prognostic favorable (5.39e-5)" "unprognostic (1.96e-1)" "unprognostic (3.59e-1)" "unprognostic (1.08e-3)" "unprognostic (1.73e-1)" "unprognostic (2.70e-1)" "unprognostic (2.07e-3)" "potential prognostic unfavorable (1.90e-4)" "unprognostic (1.18e-2)" "potential prognostic unfavorable (1.64e-5)" "unprognostic (1.95e-3)" "unprognostic (9.92e-2)" "unprognostic (1.08e-2)" "unprognostic (3.34e-3)" "unprognostic (9.51e-2)" "unprognostic (1.07e-2)" "unprognostic (1.62e-1)" "unprognostic (1.14e-1)" "unprognostic (2.53e-2)" "unprognostic (5.06e-1)" "unprognostic (2.16e-1)" "unprognostic (2.38e-1)" "unprognostic (6.61e-2)" "unprognostic (3.53e-2)" TNIP3 "ABIN-3, FLJ21162, LIND" ENSG00000050730 "TNFAIP3 interacting protein 3" Q96KP6 4 121131408-121227466 "Predicted intracellular proteins" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.0;urinary bladder: 3.9" "Cell type enhanced" "Detected in some" "Early spermatids: 23.9;Endometrial secretory cells: 45.7;Late spermatids: 92.0;Macrophages: 23.6;monocytes: 199.8;NK-cells: 19.4;T-cells: 106.3" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 199.8;Secretory cells: 45.7;Spermatogenic cell types: 92.0;T-cells: 106.3" "Cell type enriched" "Detected in some" 4 "leukocyte: 44.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory CD8 T-cell: 6.2" "Lineage enriched" "Detected in single" 10 "T-cells: 6.2" "Cancer enhanced" "Detected in many" "lymphoma: 5.9" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA043063 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 49: Hindbrain - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 31 "Nucleoplasm, Cytosol" "Nuclear bodies, Plasma membrane" "HPA043063: " "unprognostic (1.65e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (3.16e-2)" "unprognostic (2.83e-2)" "unprognostic (9.62e-3)" "unprognostic (1.68e-3)" "unprognostic (1.17e-1)" "unprognostic (1.31e-1)" "unprognostic (2.41e-2)" "unprognostic (4.16e-2)" "unprognostic (2.66e-1)" "unprognostic (1.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.69e-2)" "unprognostic (9.68e-3)" "unprognostic (1.38e-1)" TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 118.3" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 169740756.9" "Low tissue specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Approved "Plasma membrane" NA NA 13000 "Cluster 11: Esophagus - Basic cellular processes" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 26: Keratinocytes - Keratinization" 44 "Plasma membrane" "HPA037929: , HPA037930: " "unprognostic (4.75e-2)" "unprognostic (1.62e-1)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (6.85e-4)" "unprognostic (1.69e-1)" "unprognostic (7.37e-2)" "unprognostic (2.75e-1)" "unprognostic (1.41e-2)" "unprognostic (1.77e-1)" "unprognostic (6.56e-2)" "unprognostic (7.34e-3)" "unprognostic (1.05e-1)" "unprognostic (2.22e-2)" "unprognostic (3.52e-2)" "potential prognostic favorable (4.43e-4)" "unprognostic (1.26e-1)" "unprognostic (2.45e-2)" "unprognostic (3.68e-2)" "unprognostic (1.64e-2)" "unprognostic (4.32e-2)" "unprognostic (4.02e-1)" "unprognostic (1.17e-3)" "unprognostic (5.98e-3)" "unprognostic (2.94e-1)" "unprognostic (2.27e-2)" "unprognostic (6.55e-2)" "unprognostic (2.57e-1)" "unprognostic (1.43e-1)" "unprognostic (2.51e-1)" "unprognostic (7.41e-2)" "unprognostic (9.33e-2)" TNNC2 "CFAP85, FAP85" ENSG00000101470 "Troponin C2, fast skeletal type" P02585 20 45823214-45833745 "Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 102 "skeletal muscle: 28518.2;tongue: 7540.4" "Cell type enriched" "Detected in many" 7 "Thymic myoid cells: 2523.5" "Cell type enriched" "Detected in many" 7 "Stromal cells: 2523.5" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Colon Adenocarcinoma (TCGA): 37.3;Head and Neck Squamous Cell Carcinoma (TCGA): 51.2;Lung Adenocarcinoma (TCGA): 25.6;Rectum Adenocarcinoma (TCGA): 57.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 5 "colorectal cancer: 6.6;Sarcoma: 21.5" "Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in some" 5 "olfactory bulb: 6.1" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" "Skeletal myofibers: 1293070798.7" "Tissue enriched" "Detected in all" 1 "skeletal muscle: 6308344580.7" "HPA043174, HPA058481" Enhanced Approved Nucleoplasm,Vesicles No NA 780000 "Cluster 7: Non-specific - Innate immune response" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 Nucleoplasm Vesicles "HPA043174: , HPA058481: " "unprognostic (1.62e-1)" "unprognostic (8.69e-2)" "unprognostic (2.24e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (6.62e-5)" "unprognostic (3.77e-1)" "unprognostic (1.33e-2)" "unprognostic (3.62e-2)" "potential prognostic favorable (9.13e-4)" "unprognostic (3.64e-2)" "unprognostic (2.75e-1)" "unprognostic (1.86e-1)" "unprognostic (3.29e-1)" "unprognostic (1.65e-1)" "unprognostic (8.81e-2)" "unprognostic (8.93e-2)" "unprognostic (2.11e-1)" "unprognostic (1.54e-1)" "unprognostic (2.12e-3)" "unprognostic (3.01e-1)" "unprognostic (1.66e-2)" "unprognostic (1.59e-1)" TNNI2 "AMCD2B, DA2B, FSSV" ENSG00000130598 "Troponin I2, fast skeletal type" P48788 11 1838981-1841680 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 24 "skeletal muscle: 7469.2;tongue: 2445.9" "Cell type enriched" "Detected in some" 9 "Thymic myoid cells: 4847.1" "Cell type enriched" "Detected in many" 9 "Stromal cells: 4847.1" "Group enriched" "Detected in some" 10 "central nervous system macrophage: 3.3;leukocyte: 2.2" "Group enriched" "Detected in many" 10 "Bladder Urothelial Carcinoma (TCGA): 29.6;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 13.3;Head and Neck Squamous Cell Carcinoma (TCGA): 41.7;Pancreatic Adenocarcinoma (TCGA): 12.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 86.2" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bladder cancer: 8.0" "Skeletal muscle - Skeletal myocytes" "Region enriched" "Detected in single" 6 "olfactory bulb: 5.1" "Low region specificity" "Detected in some" "Cell type enriched" "Detected in some" "Skeletal myofibers: 876399324.5" "Tissue enriched" "Detected in some" "skeletal muscle: 2092424326.9" "CAB018697, HPA055938" Enhanced Approved "Plasma membrane,Intermediate filaments" NA NA 87000 "Cluster 29: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 59: Leukemia - T-cell receptor" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 13 "Plasma membrane" "Intermediate filaments" "CAB018697: , HPA055938: " "unprognostic (2.91e-2)" "unprognostic (3.91e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-2)" "unprognostic (6.39e-3)" "unprognostic (2.10e-3)" "unprognostic (1.30e-1)" "unprognostic (4.62e-3)" "unprognostic (3.49e-2)" "unprognostic (1.18e-2)" "unprognostic (1.85e-1)" "unprognostic (2.22e-2)" "unprognostic (9.66e-2)" "unprognostic (4.20e-2)" "unprognostic (9.84e-2)" "potential prognostic unfavorable (4.21e-5)" "unprognostic (1.48e-1)" "unprognostic (1.14e-2)" "unprognostic (5.81e-2)" "unprognostic (1.28e-2)" TNNT2 "CMD1D, CMH2, CMPD2" ENSG00000118194 "Troponin T2, cardiac type" P45379 1 201359008-201377764 "Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Muscle protein" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 153 "heart muscle: 8731.9" "Group enriched" "Detected in some" 14 "Cardiomyocytes: 198.7;Podocytes: 112.8" "Group enriched" "Detected in some" 14 "Myocytes: 198.7;Renal nephron cells: 112.8" "Cell type enriched" "Detected in some" 7 "hippocampal dentate gyrus: 62.9" "Cancer enhanced" "Detected in many" "Head and Neck Squamous Cell Carcinoma (TCGA): 11.7" "Group enriched" "Detected in some" 7 "cerebral cortex: 17.9;hippocampal formation: 11.0;white matter: 8.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "Rhabdoid: 30.1;Sarcoma: 110.6;testis cancer: 56.3" "Adipose visceral - Mesothelial cells, Heart muscle - Cardiomyocytes, Kidney - Podocytes" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebral cortex: 5.0" "Group enriched" "Detected in some" "Capillaries: 1017300727.7;Cardiomyocytes: 2001655534.7" "Tissue enriched" "Detected in some" "heart muscle: 2960437189.1" "CAB015371, HPA015774, HPA017888" Enhanced Uncertain "Nucleoplasm,Nucleoli,Focal adhesion sites,Microtubules" No No 72000 "Cluster 35: Non-specific - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 4 "Nucleoplasm, Nucleoli" "Focal adhesion sites, Microtubules" "CAB015371: , HPA015774: , HPA017888: " "unprognostic (1.79e-1)" "unprognostic (1.38e-1)" "unprognostic (3.84e-2)" "unprognostic (4.79e-3)" "unprognostic (1.01e-2)" "unprognostic (1.79e-1)" "unprognostic (4.33e-1)" "unprognostic (5.00e-2)" "unprognostic (1.97e-2)" "unprognostic (1.57e-2)" "unprognostic (1.41e-2)" "unprognostic (3.01e-2)" "unprognostic (2.21e-1)" "unprognostic (1.93e-1)" "unprognostic (6.70e-2)" "unprognostic (1.78e-1)" "unprognostic (3.17e-2)" TNPO2 "FLJ12155, IPO3, KPNB2B, TRN2" ENSG00000105576 "Transportin 2" O14787 19 12699201-12724011 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Pancreas - Endothelial cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in all" "Neurons: 53354397.3" "Tissue enhanced" "Detected in many" "cerebral cortex: 6902999.4" "CAB046446, HPA071498" Approved Approved Nucleoplasm,Nucleoli Yes No 11000 "Cluster 30: Non-specific - DNA binding" "Cluster 2: Non-specific - Mixed function" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 22 "Nucleoplasm, Nucleoli" "CAB046446: , HPA071498: " "unprognostic (1.94e-1)" "unprognostic (8.45e-2)" "unprognostic (3.07e-2)" "unprognostic (6.75e-2)" "unprognostic (4.56e-2)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.08e-2)" "unprognostic (4.20e-2)" "potential prognostic favorable (1.66e-4)" "unprognostic (1.05e-1)" "unprognostic (1.38e-3)" "unprognostic (2.37e-2)" "unprognostic (4.96e-2)" "unprognostic (2.47e-1)" "unprognostic (1.74e-2)" "unprognostic (7.84e-3)" "unprognostic (2.90e-2)" "unprognostic (1.57e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-2)" "unprognostic (2.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.67e-2)" "unprognostic (2.43e-3)" "unprognostic (6.94e-2)" "unprognostic (6.39e-2)" "unprognostic (1.06e-1)" "unprognostic (2.63e-2)" "unprognostic (2.25e-1)" TOGARAM1 "crescerin, Crescerin-1, FAM179B, KIAA0423" ENSG00000198718 "TOG array regulator of axonemal microtubules 1" Q9Y4F4 14 44962190-45074431 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Joubert syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 286.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 4.8" "Lineage enriched" "Detected in single" 6 "granulocytes: 4.8" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Collecting ducts: 259281.4;Fallopian tube cells: 625531.0" "Group enriched" "Detected in some" 14380 "fallopian tube: 1426066.3;intestine: 1449928.8" HPA053559 Uncertain Uncertain "Nuclear speckles,Microtubules,Primary cilium" NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 7: Non-specific - Transcription" 2 "Nuclear speckles, Microtubules" "Primary cilium" "HPA053559: " "unprognostic (3.81e-2)" "unprognostic (1.22e-1)" "unprognostic (2.26e-1)" "unprognostic (1.99e-2)" "unprognostic (1.75e-1)" "unprognostic (2.97e-1)" "unprognostic (9.47e-2)" "unprognostic (1.49e-1)" "unprognostic (1.20e-2)" "validated prognostic favorable (2.10e-6)" "validated prognostic favorable (1.67e-4)" "unprognostic (7.88e-2)" "unprognostic (4.50e-2)" "unprognostic (4.04e-1)" "unprognostic (1.58e-1)" "unprognostic (5.72e-2)" "unprognostic (5.25e-1)" "unprognostic (2.47e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-3)" "unprognostic (1.48e-2)" "unprognostic (8.09e-2)" "unprognostic (2.17e-1)" "unprognostic (4.32e-2)" "unprognostic (4.21e-2)" "unprognostic (3.98e-2)" "unprognostic (1.98e-1)" "unprognostic (3.12e-1)" "unprognostic (5.84e-2)" TOGARAM2 "Crescerin-2, FAM179A, FLJ43249, LOC165186" ENSG00000189350 "TOG array regulator of axonemal microtubules 2" Q6ZUX3 2 28956611-29052230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 7.3;fallopian tube: 19.0" "Cell type enhanced" "Detected in many" "Astrocytes: 130.4;Bergmann glia: 433.4;Cardiomyocytes: 158.6;Choroid plexus epithelial cells: 223.8;Endometrial ciliated cells: 196.8;Ependymal cells: 698.6;Epididymal efferent duct ciliated cells: 102.4;Fallopian tube ciliated cells: 211.5;Myonuclei: 119.1;Myosatellite cells: 155.5;Respiratory ciliated cells: 402.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 698.6;Glial cells: 433.4;Myocytes: 158.6;Stem cells: 155.5" "Cell type enhanced" "Detected in many" "Bergmann glia: 506.7;ependymal cell: 773.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in single" "Rhabdoid: 2.0" "Lung - Respiratory ciliated cells, Testis - Late spermatids" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Cell type enhanced" "Detected in many" "Neutrophils: 9497627.8" "Tissue enriched" "Detected in single" 24974 "lymphoid tissue: 2497397.6" "HPA037561, HPA037562, HPA075216" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 46: Brainstem - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 34: Ciliated cells - Cilia assembly & function" "Nucleoplasm, Plasma membrane" "HPA037561: , HPA037562: , HPA075216: " "unprognostic (3.06e-3)" "potential prognostic favorable (9.17e-4)" "unprognostic (6.51e-2)" "unprognostic (2.71e-3)" "unprognostic (1.09e-1)" TOLLIP IL-1RAcPIP ENSG00000078902 "Toll interacting protein" Q9H0E2 11 1274371-1309654 "Plasma proteins, Predicted intracellular proteins" "Autophagy, Immunity, Inflammatory response, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 453.4;Esophageal suprabasal cells: 298.7;Late primary spermatocytes: 236.5;Late spermatids: 828.1;Platelets: 215.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 453.4;Spermatogenic cell types: 828.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA038621, HPA038622" Enhanced Supported "Nucleoplasm,Primary cilium,Primary cilium tip,Cytosol" NA NA 63000 "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 51: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 105 Cytosol "Nucleoplasm, Primary cilium, Primary cilium tip" "HPA038621: , HPA038622: " "unprognostic (1.97e-1)" "unprognostic (2.80e-1)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" "unprognostic (3.38e-1)" "unprognostic (1.09e-1)" "unprognostic (1.93e-2)" "unprognostic (1.19e-3)" "unprognostic (3.08e-2)" "unprognostic (2.44e-2)" "potential prognostic favorable (9.35e-14)" "unprognostic (1.95e-3)" "potential prognostic favorable (5.96e-4)" "unprognostic (1.52e-1)" "unprognostic (2.37e-2)" "unprognostic (1.11e-1)" "unprognostic (2.83e-1)" "unprognostic (7.59e-3)" "unprognostic (2.16e-1)" "unprognostic (9.44e-2)" "unprognostic (9.80e-3)" "unprognostic (3.24e-2)" "unprognostic (5.52e-2)" "unprognostic (3.38e-1)" "unprognostic (3.72e-1)" "unprognostic (3.44e-1)" "unprognostic (8.13e-2)" "unprognostic (1.69e-1)" "unprognostic (1.40e-1)" "unprognostic (4.34e-1)" "unprognostic (3.54e-1)" TOP1 ENSG00000198900 "DNA topoisomerase I" P11387 20 41028822-41124487 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 2: 1249.6;Neutrophils: 1184.4;Syncytiotrophoblasts: 1442.3" "Cell type enhanced" "Detected in all" "Trophoblast cells: 1442.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "CAB009058, HPA019039" Supported Supported "Nucleoplasm,Nucleoli fibrillar center" No Yes 5400 "Cluster 29: Non-specific - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 62: Non-specific - Plasma proteins" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 416 "Nucleoplasm, Nucleoli fibrillar center" "CAB009058: , HPA019039: " "unprognostic (2.07e-2)" "unprognostic (1.95e-2)" "unprognostic (3.01e-1)" "unprognostic (7.66e-2)" "unprognostic (3.48e-2)" "unprognostic (2.96e-1)" "unprognostic (1.99e-1)" "unprognostic (2.06e-1)" "unprognostic (5.51e-3)" "unprognostic (4.49e-3)" "unprognostic (2.10e-3)" "unprognostic (7.38e-2)" "unprognostic (1.55e-2)" "potential prognostic unfavorable (2.55e-4)" "unprognostic (5.84e-3)" "unprognostic (6.18e-3)" "potential prognostic unfavorable (1.37e-4)" "unprognostic (8.72e-2)" "unprognostic (7.57e-2)" "unprognostic (1.92e-1)" "unprognostic (3.36e-3)" "unprognostic (5.78e-3)" "potential prognostic unfavorable (1.85e-5)" "unprognostic (6.68e-2)" "unprognostic (8.02e-2)" "unprognostic (7.46e-2)" "unprognostic (9.93e-2)" "unprognostic (7.55e-2)" "unprognostic (2.09e-1)" "unprognostic (6.59e-2)" "unprognostic (2.44e-1)" TOP2A "TOP2, TOP2alpha, TOPIIA" ENSG00000131747 "DNA topoisomerase II alpha" P11388 17 40388525-40417896 "Cancer-related genes, Enzymes, Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "Biological rhythms" "DNA-binding, Isomerase, Topoisomerase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 119.0;testis: 62.4" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 211.0;Early primary spermatocytes: 818.4;Enteric transient amplifying cells: 152.2;Erythrocyte progenitors: 500.6;Gastric progenitor cells: 126.9;Hofbauer cells: 172.0;Late primary spermatocytes: 140.7;Megakaryocyte progenitors: 334.6;Monocyte progenitors: 686.4;Neutrophil progenitors: 176.4" "Cell type enhanced" "Detected in many" "Erythrocytes: 500.6;Megakaryocytes: 334.6;Mononuclear phagocytes: 686.4;Spermatogenic cell types: 818.4" "Cell type enriched" "Detected in single" 4 "leukocyte: 3.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in some" "T-reg: 2.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Group enriched" "Detected in many" 4 "basal ganglia: 4.2;white matter: 8.0" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 21644459.4;Neutrophils: 9806256.7" "Group enriched" "Detected in some" "bone marrow: 5785937.8;intestine: 3678541.3" "CAB002448, HPA006458, HPA026773" Enhanced Approved Supported Nucleoplasm,Nucleoli Yes Yes 8800 "Cluster 9: T-regs - Cell cycle regulation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 12: Non-specific - Vasculature" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 27: Non-specific - Cell proliferation" 235 Nucleoplasm Nucleoli "CAB002448: , HPA006458: , HPA026773: " "unprognostic (6.46e-2)" "unprognostic (2.94e-1)" "unprognostic (1.81e-1)" "unprognostic (2.29e-3)" "unprognostic (3.78e-2)" "unprognostic (4.02e-3)" "unprognostic (9.86e-2)" "unprognostic (2.01e-2)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (2.50e-6)" "validated prognostic unfavorable (1.23e-10)" "validated prognostic unfavorable (3.57e-6)" "potential prognostic unfavorable (4.32e-8)" "validated prognostic unfavorable (5.06e-5)" "validated prognostic unfavorable (5.19e-7)" "potential prognostic unfavorable (3.30e-5)" "unprognostic (1.47e-3)" "unprognostic (1.76e-3)" "unprognostic (7.58e-2)" "unprognostic (1.31e-1)" "unprognostic (3.90e-1)" "unprognostic (1.76e-3)" "unprognostic (1.32e-2)" "unprognostic (3.99e-2)" "unprognostic (2.25e-1)" "potential prognostic favorable (5.55e-4)" "unprognostic (3.72e-3)" "unprognostic (8.19e-2)" "unprognostic (1.82e-1)" "unprognostic (3.45e-2)" "unprognostic (6.49e-2)" TOPAZ1 "C3orf77, FLJ36157" ENSG00000173769 "Testis and ovary specific TOPAZ 1" Q8N9V7 3 44241886-44332098 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 33 "testis: 3.3" "Group enriched" "Detected in some" 7 "Differentiating spermatogonia: 76.3;Early primary spermatocytes: 217.1;Undifferentiated spermatogonia: 82.3" "Cell type enriched" "Detected in some" 23 "Spermatogenic cell types: 217.1" "Cell type enhanced" "Detected in many" "hippocampal CA1-3: 5.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Spermatocytes" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 5264 "intestine: 526442.7" "HPA047431, HPA051034" Uncertain Approved "Acrosome,Mid piece" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 3: Early primary spermatocytes - Early meiosis" "Acrosome, Mid piece" "HPA047431: , HPA051034: " TOPBP1 "Dpb11, KIAA0259, TOP2BP1" ENSG00000163781 "DNA topoisomerase II binding protein 1" Q92547 3 133598175-133662380 "Essential proteins, Predicted intracellular proteins" "DNA damage, DNA repair" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 128.7;Late spermatids: 156.4;Monocyte progenitors: 170.4;Neutrophil progenitors: 204.0" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 170.4;Neutrophils: 204.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Granulosa cells: 218002.9;Neurons: 358750.4" "Tissue enriched" "Detected in some" "intestine: 8261196.2" "CAB022451, HPA036738, HPA036739" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 59 "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB022451: , HPA036738: , HPA036739: " "unprognostic (5.84e-2)" "unprognostic (4.23e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-1)" "unprognostic (2.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.52e-1)" "unprognostic (4.13e-3)" "unprognostic (5.41e-2)" "potential prognostic unfavorable (5.26e-4)" "unprognostic (2.40e-2)" "unprognostic (2.86e-1)" "unprognostic (7.26e-2)" "potential prognostic unfavorable (1.05e-4)" "unprognostic (1.13e-2)" "unprognostic (3.98e-2)" "unprognostic (2.84e-3)" "unprognostic (5.13e-2)" "unprognostic (6.97e-2)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.33e-3)" "potential prognostic unfavorable (4.09e-4)" "unprognostic (6.13e-3)" "potential prognostic favorable (7.14e-4)" "unprognostic (4.08e-2)" "unprognostic (6.60e-2)" "unprognostic (1.37e-1)" "unprognostic (2.04e-1)" "unprognostic (2.00e-1)" "unprognostic (2.39e-1)" TOR1AIP1 "FLJ13142, LAP1, LAP1B, LAP1C" ENSG00000143337 "Torsin 1A interacting protein 1" Q5JTV8 1 179882042-179920077 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 386.9;Late spermatids: 288.5;Neutrophil progenitors: 288.8;Neutrophils: 262.1" "Cell type enhanced" "Detected in many" "Neutrophils: 288.8;Spermatogenic cell types: 386.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Fibroblasts, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 140489942.6" "Tissue enhanced" "Detected in all" "lymphoid tissue: 35550435.8" "HPA047151, HPA050546, HPA070991" Enhanced Supported "Nuclear membrane" NA NA 11000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 39 "Nuclear membrane" "HPA047151: , HPA050546: , HPA070991: " "unprognostic (6.61e-3)" "unprognostic (1.58e-1)" "unprognostic (1.61e-1)" "unprognostic (8.17e-3)" "unprognostic (2.05e-1)" "unprognostic (7.61e-3)" "unprognostic (1.30e-1)" "unprognostic (3.18e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-1)" "potential prognostic favorable (7.59e-6)" "unprognostic (1.20e-3)" "unprognostic (9.11e-2)" "unprognostic (2.93e-1)" "unprognostic (3.16e-1)" "unprognostic (3.12e-1)" "unprognostic (7.81e-2)" "unprognostic (1.23e-3)" "unprognostic (1.76e-1)" "unprognostic (3.08e-2)" "unprognostic (6.97e-3)" "unprognostic (1.48e-1)" "unprognostic (1.74e-1)" "unprognostic (1.12e-1)" "unprognostic (1.78e-3)" "unprognostic (1.81e-2)" "unprognostic (1.80e-2)" "unprognostic (2.86e-3)" "unprognostic (2.89e-2)" "unprognostic (5.81e-2)" "unprognostic (1.86e-1)" TP53 "LFS1, p53" ENSG00000141510 "Tumor protein p53" P04637 17 7661779-7687538 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors, Transporters" "Apoptosis, Biological rhythms, Cell cycle, Host-virus interaction, Necrosis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Cancer-related genes, Disease variant, Li-Fraumeni syndrome, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "astrocyte: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002973, CAB039238, CAB039239, HPA051244, HPA063532, CAB072876" Enhanced Enhanced Nucleoplasm,Vesicles,Cytosol Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 54: Non-specific - Ribosome" "Cluster 44: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 998 Nucleoplasm "Vesicles, Cytosol" "CAB002973: , CAB039238: , CAB039239: , CAB072876: , HPA051244: , HPA063532: " "unprognostic (5.89e-2)" "unprognostic (2.13e-3)" "potential prognostic favorable (5.06e-4)" "unprognostic (2.07e-1)" "unprognostic (4.64e-2)" "potential prognostic favorable (5.72e-4)" "unprognostic (8.05e-2)" "unprognostic (1.85e-1)" "unprognostic (8.66e-2)" "unprognostic (1.02e-1)" "unprognostic (3.74e-2)" "unprognostic (8.43e-3)" "unprognostic (3.70e-2)" "unprognostic (1.11e-2)" "unprognostic (3.46e-2)" "unprognostic (3.42e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (6.21e-2)" "unprognostic (4.78e-2)" "unprognostic (5.54e-2)" "unprognostic (6.70e-2)" "unprognostic (1.23e-1)" "unprognostic (1.28e-3)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (4.18e-3)" "unprognostic (8.20e-2)" "unprognostic (3.49e-1)" "unprognostic (1.45e-2)" "unprognostic (2.07e-2)" TP53BP1 "53BP1, p202, TDRD30" ENSG00000067369 "Tumor protein p53 binding protein 1" Q12888 15 43403061-43510728 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 329.4;Somatotrophs: 324.5;Thyrotrophs: 300.3" "Cell type enhanced" "Detected in many" "Pituitary endocrine cells: 329.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 45451932.1;Neurons: 125874946.3" "Low tissue specificity" "Detected in many" "CAB004083, HPA008788, HPA022133, CAB079980" Supported Enhanced "Nucleoplasm,Nuclear bodies" No No 5500 "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 58: Non-specific - Nuclear processes" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 151 "Nuclear bodies" Nucleoplasm "CAB004083: , CAB079980: , HPA008788: , HPA022133: " "unprognostic (6.68e-3)" "unprognostic (1.32e-1)" "unprognostic (9.21e-2)" "unprognostic (5.88e-3)" "unprognostic (8.25e-2)" "unprognostic (2.08e-1)" "unprognostic (5.99e-3)" "potential prognostic favorable (1.49e-4)" "unprognostic (2.17e-1)" "unprognostic (3.35e-2)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.97e-1)" "unprognostic (7.03e-2)" "unprognostic (1.52e-1)" "unprognostic (4.08e-1)" "unprognostic (1.04e-1)" "unprognostic (3.18e-1)" "unprognostic (4.69e-2)" "unprognostic (2.49e-2)" "unprognostic (2.92e-1)" "unprognostic (4.40e-1)" "unprognostic (4.44e-3)" "unprognostic (2.00e-1)" "unprognostic (5.80e-2)" "unprognostic (2.58e-1)" "unprognostic (2.85e-1)" "unprognostic (2.63e-1)" "unprognostic (1.89e-1)" "unprognostic (3.14e-1)" "unprognostic (1.04e-1)" TP53INP1 "DKFZp434M1317, FLJ22139, P53DINP1, SIP, Teap, TP53INP1A, TP53INP1B" ENSG00000164938 "Tumor protein p53 inducible nuclear protein 1" Q96A56 8 94925972-94949378 "Predicted intracellular proteins" "Apoptosis, Autophagy, Transcription, Transcription regulation" "Activator, Antioxidant" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 95.3" "Cell type enhanced" "Detected in many" "B-cells: 198.6;Hepatocytes: 229.7;Neutrophils: 150.4;Pancreatic acinar cells: 141.2;Plasma cells: 471.9;Thymocytes: 283.7" "Cell type enhanced" "Detected in all" "Plasma cells: 471.9;T-cells: 283.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 51.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 54.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 54.8" "Group enriched" "Detected in all" 4 "Myeloma: 94.8;prostate cancer: 61.5;testis cancer: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 4187 "lymphoid tissue: 418693.2" HPA005856 Uncertain Supported Cytosol NA NA "Cluster 32: Basophils - Transcription" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 16 Cytosol "HPA005856: " "potential prognostic favorable (3.98e-4)" "unprognostic (4.65e-2)" "unprognostic (2.88e-1)" "unprognostic (1.03e-1)" "unprognostic (3.15e-1)" "unprognostic (1.52e-1)" "unprognostic (9.39e-2)" "unprognostic (3.06e-1)" "potential prognostic favorable (2.45e-4)" "unprognostic (4.98e-2)" "unprognostic (3.32e-1)" "potential prognostic favorable (1.13e-4)" "unprognostic (8.75e-2)" "unprognostic (1.23e-1)" "unprognostic (5.68e-2)" "unprognostic (2.19e-3)" "unprognostic (7.21e-2)" "unprognostic (2.14e-1)" "unprognostic (1.07e-1)" "unprognostic (3.40e-2)" "unprognostic (1.83e-2)" "unprognostic (6.34e-2)" "unprognostic (1.26e-1)" "unprognostic (2.51e-2)" "unprognostic (4.26e-2)" "unprognostic (1.44e-3)" "unprognostic (2.47e-2)" "unprognostic (1.45e-1)" "unprognostic (3.23e-1)" "unprognostic (9.75e-2)" "unprognostic (4.24e-2)" TP63 "EEC3, KET, NBP, OFC8, p40, p51, p53CP, p63, p73H, p73L, SHFM4, TP53CP, TP53L, TP73L" ENSG00000073282 "Tumor protein p63" Q9H3D4 3 189631389-189897276 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Apoptosis, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Cancer-related genes, Disease variant, Ectodermal dysplasia, Premature ovarian failure" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 65.3;skin 1: 129.6;vagina: 52.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 759.5;Basal prostatic cells: 387.2;Esophageal basal cells: 231.3;Medullary thymic epithelial cells: 254.4;Myonuclei: 1460.7;Papillary tip epithelial cells: 344.5;Respiratory basal cells: 414.7;Suprabasal keratinocytes: 528.3;Thymic myoid cells: 1309.3" "Cell type enhanced" "Detected in many" "Basal cells: 759.5;Myocytes: 1460.7;Stromal cells: 1309.3;Suprabasal cells: 528.3" "Group enriched" "Detected in many" 9 "ependymal cell: 95.5;fibroblast: 212.0;pericyte: 102.4" "Group enriched" "Detected in many" 15 "Bladder Urothelial Carcinoma (TCGA): 55.5;Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 111.2;Head and Neck Squamous Cell Carcinoma (TCGA): 184.6;Lung Squamous Cell Carcinoma (TCGA): 172.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Esophageal cancer: 114.7;Gallbladder cancer: 194.8;head and neck cancer: 125.5" "Colon - Enteric glia cells, Lung - Respiratory ciliated cells, Prostate - Prostate basal glandular cells, Skin - Keratinocyte (other), Testis - Spermatogonia" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in some" "Keratinocytes: 12634353.6;Oocytes: 3224589.1" "Tissue enriched" "Detected in single" 576 "salivary gland: 57620.3" "CAB000083, HPA006288, HPA006289, HPA007009, HPA007010" Enhanced Enhanced Nucleoplasm NA NA "Cluster 23: B-cells - Immunoglobulins" "Cluster 58: Skin - Keratinization" "Cluster 48: Non-specific - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 49 Nucleoplasm "CAB000083: , HPA006288: , HPA006289: , HPA007009: , HPA007010: " "unprognostic (2.81e-1)" "potential prognostic favorable (5.55e-5)" "unprognostic (2.92e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (2.48e-2)" "unprognostic (1.18e-1)" "unprognostic (2.92e-2)" "unprognostic (2.19e-1)" "unprognostic (4.93e-2)" "unprognostic (1.84e-2)" "unprognostic (5.08e-3)" "unprognostic (5.64e-3)" "unprognostic (3.31e-2)" "unprognostic (2.11e-1)" "unprognostic (7.46e-2)" "unprognostic (2.29e-2)" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" "unprognostic (2.23e-1)" TPD52 "D52, hD52, N8L" ENSG00000076554 "Tumor protein D52" P55327 8 80034745-80231232 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 173.2" "Cell type enhanced" "Detected in many" "B-cells: 327.7;Choroid plexus epithelial cells: 361.4;Plasma cells: 386.3;Salivary ionocytes: 331.5" "Cell type enhanced" "Detected in many" "Plasma cells: 386.3" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 370.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 49.9" "Group enriched" "Detected in many" 5 "B-cells: 49.9;NK-cells: 15.0;T-cells: 21.8" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Lung - Alveolar cells type 2, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "salivary gland: 125398470.0" "HPA028427, HPA062167" Enhanced Approved "Golgi apparatus,Primary cilium,Cytosol" NA NA 270000 "Cluster 24: Non-specific - Transcription" "Cluster 42: Retina - Visual perception" "Cluster 14: Neurons - Synaptic function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 18 Cytosol "Golgi apparatus, Primary cilium" "HPA028427: , HPA062167: " "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.39e-5)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (2.61e-2)" "unprognostic (2.86e-1)" "unprognostic (9.73e-2)" "unprognostic (9.86e-2)" "unprognostic (2.54e-1)" "unprognostic (8.53e-2)" "unprognostic (9.93e-2)" "potential prognostic unfavorable (4.72e-4)" "potential prognostic unfavorable (1.50e-6)" "unprognostic (6.21e-3)" "unprognostic (4.98e-3)" "unprognostic (1.42e-2)" "unprognostic (2.89e-1)" "unprognostic (2.53e-1)" "unprognostic (2.82e-1)" "unprognostic (1.28e-1)" "unprognostic (6.15e-2)" "unprognostic (2.08e-1)" "unprognostic (3.21e-2)" "unprognostic (2.19e-1)" "unprognostic (2.50e-1)" "unprognostic (2.30e-2)" "unprognostic (1.57e-1)" "unprognostic (4.56e-2)" "unprognostic (3.89e-1)" "unprognostic (3.26e-1)" "unprognostic (1.68e-2)" TPI1 ENSG00000111669 "Triosephosphate isomerase 1" P60174 12 6867119-6870948 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Gluconeogenesis, Glycolysis" "Isomerase, Lyase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2315.7;tongue: 1873.5" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 5404.6;Esophageal basal cells: 1694.7;Esophageal suprabasal cells: 2600.0;Extravillous trophoblasts: 2184.7;Migrating cytotrophoblasts: 1772.3;Syncytiotrophoblasts: 1737.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 5404.6;Suprabasal cells: 2600.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Skeletal myofibers: 2691633211.0" "Tissue enhanced" "Detected in all" "skeletal muscle: 5032737874.0" "HPA050924, HPA053568" Uncertain Approved Nucleoplasm NA NA 83000000 "Cluster 29: Non-specific - Unknown function" "Cluster 52: Non-specific - Cellular respiration" "Cluster 14: Neurons - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 85: Squamous epithelial cells - Keratinization" 32 Nucleoplasm "HPA050924: , HPA053568: " "potential prognostic unfavorable (2.28e-4)" "unprognostic (1.30e-1)" "unprognostic (3.76e-1)" "unprognostic (1.07e-1)" "unprognostic (3.43e-1)" "unprognostic (5.78e-2)" "unprognostic (2.57e-2)" "unprognostic (3.11e-1)" "unprognostic (6.91e-3)" "unprognostic (4.46e-3)" "unprognostic (9.07e-3)" "unprognostic (1.12e-1)" "unprognostic (3.10e-2)" "validated prognostic unfavorable (3.11e-5)" "validated prognostic unfavorable (7.83e-11)" "potential prognostic unfavorable (5.69e-5)" "unprognostic (1.75e-3)" "unprognostic (4.01e-2)" "unprognostic (3.71e-1)" "unprognostic (4.71e-2)" "unprognostic (1.01e-1)" "unprognostic (2.62e-2)" "unprognostic (5.87e-2)" "unprognostic (1.24e-1)" "unprognostic (2.29e-1)" "unprognostic (4.12e-2)" "unprognostic (1.62e-1)" "unprognostic (7.84e-2)" "unprognostic (3.38e-1)" "unprognostic (5.13e-2)" "unprognostic (1.19e-1)" TPPP "p25, p25alpha, TPPP/p25, TPPP1" ENSG00000171368 "Tubulin polymerization promoting protein" O94811 5 659862-693352 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 133.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 41.8;Brain inhibitory neurons: 45.3;Corticotrophs: 38.9;Endometrial ciliated cells: 35.5;Ependymal cells: 41.6;Fallopian tube ciliated cells: 45.0;Oligodendrocytes: 125.0;Other brain neurons: 41.9;Respiratory ciliated cells: 38.4;Thyrotrophs: 37.2" "Cell type enhanced" "Detected in many" "Glial cells: 125.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal medulla cells, Heart muscle - Cardiomyocytes, Prostate - Smooth muscle cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 305228226.3;Microglia and Neuropil: 204660110.0;Neurons: 102324576.3" "Tissue enriched" "Detected in many" "cerebral cortex: 359984817.9" "HPA036575, HPA036576" Enhanced Supported Mitochondria,Cytosol NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 34: Non-specific - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 80: Oligodendrocytes - Myelination" 16 "Mitochondria, Cytosol" "HPA036575: , HPA036576: " "unprognostic (2.87e-2)" "unprognostic (1.36e-1)" "unprognostic (6.03e-2)" "unprognostic (2.02e-1)" "unprognostic (4.69e-2)" "unprognostic (3.89e-2)" "unprognostic (4.35e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-2)" "unprognostic (1.81e-2)" "potential prognostic favorable (2.17e-5)" "unprognostic (4.45e-3)" "unprognostic (1.14e-2)" "unprognostic (1.53e-1)" "unprognostic (5.42e-2)" "unprognostic (6.59e-3)" "unprognostic (2.40e-2)" "unprognostic (2.30e-1)" "unprognostic (4.28e-2)" "unprognostic (1.86e-1)" "unprognostic (8.34e-2)" "unprognostic (2.91e-3)" "unprognostic (1.00e-1)" "unprognostic (7.92e-3)" "unprognostic (1.01e-1)" "unprognostic (2.18e-1)" "unprognostic (3.99e-1)" "unprognostic (4.01e-2)" "unprognostic (1.34e-1)" "unprognostic (2.36e-2)" "unprognostic (9.53e-2)" TPX2 "C20orf1, C20orf2, DIL-2, FLS353, HCA519, p100" ENSG00000088325 "TPX2 microtubule nucleation factor" Q9ULW0 20 31739271-31801805 "Cancer-related genes, Essential proteins, Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell division, Mitosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 45.3;lymphoid tissue: 65.5;testis: 28.7" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 71.5;Early primary spermatocytes: 120.7;Enteric transient amplifying cells: 61.4;Erythrocyte progenitors: 227.3;Esophageal basal cells: 64.2;Extravillous trophoblasts: 86.7;Gastric progenitor cells: 64.1;Late primary spermatocytes: 66.4;Megakaryocyte progenitors: 157.6;Monocyte progenitors: 274.1;Neutrophil progenitors: 112.3" "Cell type enhanced" "Detected in many" "Erythrocytes: 227.3;Megakaryocytes: 157.6;Mononuclear phagocytes: 274.1;Neutrophils: 112.3;Spermatogenic cell types: 120.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 8.1" "Group enriched" "Detected in many" 5 "granulocytes: 5.0;NK-cells: 3.6;T-cells: 8.1" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 17905 "Granulosa cells: 1790523.2" "Tissue enriched" "Detected in single" 187 "bone marrow: 18668.6" HPA005487 Enhanced Supported "Nucleoplasm,Cytokinetic bridge,Mitotic spindle" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 53: Neurons - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 24 Nucleoplasm "Cytokinetic bridge, Mitotic spindle" "HPA005487: " "unprognostic (1.09e-2)" "unprognostic (1.23e-1)" "unprognostic (4.47e-2)" "unprognostic (6.19e-2)" "unprognostic (9.47e-2)" "unprognostic (4.78e-2)" "unprognostic (3.16e-1)" "unprognostic (4.14e-2)" "unprognostic (3.06e-1)" "potential prognostic unfavorable (1.64e-5)" "validated prognostic unfavorable (5.19e-9)" "validated prognostic unfavorable (4.20e-8)" "potential prognostic unfavorable (4.73e-13)" "validated prognostic unfavorable (4.31e-7)" "validated prognostic unfavorable (2.38e-10)" "validated prognostic unfavorable (1.66e-5)" "validated prognostic unfavorable (8.22e-4)" "unprognostic (1.43e-2)" "unprognostic (7.24e-3)" "unprognostic (1.44e-1)" "unprognostic (6.74e-2)" "validated prognostic unfavorable (1.36e-5)" "validated prognostic unfavorable (7.35e-4)" "unprognostic (6.46e-2)" "unprognostic (4.71e-2)" "unprognostic (2.05e-2)" "unprognostic (4.14e-2)" "unprognostic (4.78e-2)" "unprognostic (3.51e-1)" "unprognostic (3.29e-2)" "unprognostic (6.83e-2)" TRA2A "AWMS1, htra-2-alpha" ENSG00000164548 "Transformer 2 alpha homolog" Q13595 7 23504780-23532041 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 13498697.5" "Tissue enhanced" "Detected in all" "lymphoid tissue: 34506905.5" HPA054018 Uncertain Supported Nucleoplasm,Nucleoli,Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 55: Non-specific - Transcription" "Cluster 67: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 49 Nucleoli "Nucleoplasm, Vesicles" "HPA054018: " "unprognostic (7.32e-2)" "unprognostic (8.29e-2)" "unprognostic (1.68e-1)" "unprognostic (1.31e-1)" "unprognostic (1.92e-1)" "unprognostic (1.09e-1)" "unprognostic (1.18e-1)" "unprognostic (1.20e-1)" "unprognostic (3.82e-1)" "unprognostic (5.67e-2)" "unprognostic (1.48e-2)" "unprognostic (4.01e-1)" "unprognostic (9.48e-2)" "potential prognostic unfavorable (1.69e-4)" "unprognostic (4.29e-2)" "unprognostic (1.56e-1)" "unprognostic (2.52e-1)" "potential prognostic favorable (2.44e-4)" "unprognostic (1.70e-1)" "unprognostic (2.05e-1)" "unprognostic (1.79e-1)" "unprognostic (4.54e-3)" "potential prognostic unfavorable (1.08e-4)" "unprognostic (1.79e-1)" "unprognostic (1.73e-1)" "unprognostic (1.65e-1)" "unprognostic (1.26e-1)" "unprognostic (7.37e-2)" "unprognostic (4.37e-1)" "unprognostic (1.97e-1)" "unprognostic (7.94e-2)" TRAF3IP1 "DKFZP434F124, FAP116, IFT54, MIP-T3, MIPT3" ENSG00000204104 "TRAF3 interacting protein 1" Q8TDR0 2 238320441-238400897 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 356.5;Ependymal cells: 186.0;Fallopian tube ciliated cells: 344.3;Respiratory ciliated cells: 474.7" "Cell type enhanced" "Detected in all" "Ciliated cells: 474.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.0" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 7880739.4" "Tissue enriched" "Detected in single" 66533 "fallopian tube: 6653292.4" "HPA037857, HPA037858" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies,Primary cilium transition zone" NA NA "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 107: Ciliated cells - Cilia assembly & function" 32 "Nuclear bodies, Primary cilium transition zone" "Nucleoplasm, Nucleoli fibrillar center" "HPA037857: , HPA037858: " "unprognostic (5.10e-2)" "unprognostic (1.80e-1)" "unprognostic (3.08e-2)" "unprognostic (2.88e-1)" "unprognostic (6.58e-2)" "potential prognostic favorable (2.44e-4)" "unprognostic (1.54e-1)" "unprognostic (7.16e-3)" "unprognostic (1.46e-1)" "unprognostic (2.61e-1)" "potential prognostic favorable (1.30e-5)" "unprognostic (3.98e-3)" "unprognostic (2.21e-1)" "unprognostic (6.91e-3)" "unprognostic (2.23e-2)" "unprognostic (8.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.35e-2)" "unprognostic (4.85e-2)" "unprognostic (1.33e-1)" "unprognostic (3.52e-2)" "unprognostic (9.15e-3)" "unprognostic (1.08e-2)" "unprognostic (1.11e-2)" "unprognostic (6.42e-3)" "unprognostic (2.44e-2)" "unprognostic (1.84e-1)" "unprognostic (9.06e-2)" "unprognostic (5.84e-2)" "unprognostic (1.33e-1)" TRAF5 RNF84 ENSG00000082512 "TNF receptor associated factor 5" O00463 1 211326615-211374946 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "B-cells: 159.4;Choroid plexus epithelial cells: 163.4;Mast cells: 96.1;Podocytes: 110.7;Thymocytes: 122.0;Tuft cells: 103.8" "Cell type enhanced" "Detected in many" "B-cells: 159.4;Ciliated cells: 163.4" "Cell type enhanced" "Detected in all" "choroid plexus epithelial cell: 159.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 6 "choroid plexus: 55.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Smooth muscle cells, Spleen - B-cells (Spleen), Thyroid gland - T-cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 663581.1;T-cells: 691644.1" "Tissue enriched" "Detected in single" 12556 "lymphoid tissue: 1255552.0" "HPA008052, CAB010277" Enhanced Supported Centrosome,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 23: Choroid plexus - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 64 Cytosol Centrosome "CAB010277: , HPA008052: " "unprognostic (1.05e-1)" "unprognostic (6.39e-2)" "unprognostic (2.54e-2)" "unprognostic (1.24e-2)" "unprognostic (6.78e-2)" "unprognostic (3.70e-2)" "unprognostic (8.47e-2)" "unprognostic (2.41e-2)" "unprognostic (2.86e-2)" "unprognostic (1.07e-1)" "unprognostic (1.44e-1)" "unprognostic (1.08e-1)" "unprognostic (2.88e-2)" "unprognostic (1.88e-3)" "unprognostic (1.67e-1)" "unprognostic (3.59e-2)" "unprognostic (1.23e-1)" "unprognostic (3.73e-1)" "unprognostic (2.00e-2)" "unprognostic (8.18e-3)" "unprognostic (1.42e-2)" "unprognostic (6.10e-2)" "unprognostic (3.35e-2)" "unprognostic (1.24e-1)" "unprognostic (2.59e-1)" "unprognostic (5.96e-2)" "unprognostic (1.99e-1)" "unprognostic (3.03e-1)" "unprognostic (5.84e-2)" "unprognostic (7.87e-2)" "unprognostic (1.67e-1)" TRAM1L1 MGC26568 ENSG00000174599 "Translocation associated membrane protein 1 like 1" Q8N609 4 117083554-117085576 "Predicted membrane proteins, Transporters" "Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 7.1;Epididymal principal cells: 9.1;Oligodendrocyte progenitor cells: 11.2;Oligodendrocytes: 14.7;Other brain neurons: 7.6;Retinal pigment epithelial cells: 12.8;Undifferentiated spermatogonia: 7.0" "Cell type enhanced" "Detected in many" "Glial cells: 14.7;Pigment cells: 12.8;Reproductive supporting cells: 9.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA044560 Uncertain Uncertain Mitochondria NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 80: Oligodendrocytes - Myelination" 20 Mitochondria "HPA044560: " "unprognostic (1.33e-1)" "unprognostic (3.03e-1)" "unprognostic (3.31e-2)" "unprognostic (1.43e-1)" "unprognostic (1.73e-2)" "unprognostic (2.51e-2)" "potential prognostic favorable (1.24e-5)" "unprognostic (1.78e-1)" "unprognostic (8.76e-2)" "unprognostic (2.35e-1)" "unprognostic (2.27e-1)" "unprognostic (6.18e-2)" "unprognostic (7.12e-3)" "unprognostic (2.28e-1)" "unprognostic (2.00e-1)" "unprognostic (2.97e-3)" "unprognostic (5.23e-1)" "unprognostic (1.89e-1)" "unprognostic (2.01e-2)" "unprognostic (1.57e-1)" "unprognostic (3.57e-2)" "unprognostic (6.95e-2)" TRAPPC11 "C4orf41, FLJ12716, foigr, gry" ENSG00000168538 "Trafficking protein particle complex subunit 11" Q7Z392 4 183659267-183713594 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Transport" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "intestine: 4544605.6" HPA038173 Uncertain Vesicles,Cytosol NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 31: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 7: Non-specific - Transcription" 42 Cytosol Vesicles "HPA038173: " "unprognostic (5.86e-2)" "unprognostic (1.04e-1)" "unprognostic (2.81e-2)" "unprognostic (2.76e-2)" "unprognostic (3.12e-1)" "unprognostic (2.43e-1)" "unprognostic (1.42e-1)" "unprognostic (2.69e-2)" "unprognostic (6.19e-2)" "potential prognostic favorable (9.71e-7)" "unprognostic (1.08e-3)" "unprognostic (8.07e-2)" "unprognostic (6.13e-2)" "unprognostic (1.34e-1)" "unprognostic (8.80e-3)" "unprognostic (4.79e-2)" "unprognostic (1.81e-1)" "unprognostic (3.46e-3)" "unprognostic (3.61e-2)" "unprognostic (4.72e-2)" "unprognostic (2.24e-2)" "unprognostic (3.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-2)" "unprognostic (2.33e-1)" "unprognostic (4.73e-1)" "unprognostic (1.62e-1)" "unprognostic (5.48e-2)" "unprognostic (2.59e-1)" TRAPPC9 "IKBKBBP, KIAA1882, MRT13, NIBP, T1, TRS120" ENSG00000167632 "Trafficking protein particle complex subunit 9" Q96Q05 8 139727725-140458579 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 886.2;Somatotrophs: 744.8" "Cell type enhanced" "Detected in all" "Pituitary endocrine cells: 886.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "cerebral cortex: 8959771.3;lymphoid tissue: 6123438.2" HPA026579 Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 45: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 22 "Golgi apparatus, Vesicles" Nucleoplasm "HPA026579: " "unprognostic (1.17e-1)" "unprognostic (5.37e-3)" "unprognostic (2.30e-1)" "unprognostic (6.02e-2)" "unprognostic (5.81e-2)" "unprognostic (2.76e-1)" "unprognostic (3.76e-1)" "unprognostic (3.26e-2)" "unprognostic (3.38e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-3)" "unprognostic (1.34e-1)" "unprognostic (7.71e-2)" "unprognostic (2.62e-1)" "unprognostic (2.97e-2)" "unprognostic (4.89e-3)" "unprognostic (5.92e-2)" "unprognostic (8.17e-3)" "unprognostic (3.90e-3)" "unprognostic (1.16e-1)" "unprognostic (3.69e-1)" "unprognostic (7.50e-2)" "unprognostic (5.26e-3)" "unprognostic (1.77e-1)" "unprognostic (2.02e-1)" "unprognostic (2.24e-1)" "unprognostic (2.61e-1)" "unprognostic (1.61e-1)" "unprognostic (1.78e-1)" "unprognostic (1.81e-1)" "unprognostic (4.22e-1)" TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "lymphoid tissue: 74.3" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 18.6;Innate lymphoid cells: 24.1;NK-cells: 42.1;T-cells: 145.4;Thymocytes: 52.5" "Cell type enhanced" "Detected in many" "Innate lymphoid cells: 24.1;NK-cells: 42.1;T-cells: 145.4" "Cell type enriched" "Detected in single" 67 "leukocyte: 56.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 396.7" "Group enriched" "Detected in many" 155 "granulocytes: 396.7;T-cells: 314.1" "Cancer enhanced" "Detected in some" "Leukemia: 10.3;Myeloma: 2.8" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Kidney - T-cells, Liver - T-cells, Minor Salivary Gland - T-cells, Prostate - T-cells, Skin - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 2075 "T-cells: 207523.1" "Tissue enriched" "Detected in single" 11301 "lymphoid tissue: 1130107.2" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 80: Thymus - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 2 "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: , HPA072760: " "unprognostic (1.02e-3)" "unprognostic (6.87e-2)" "potential prognostic favorable (5.68e-4)" "unprognostic (2.66e-1)" "unprognostic (1.01e-1)" "unprognostic (8.96e-2)" "unprognostic (1.92e-2)" "unprognostic (1.26e-2)" "unprognostic (8.25e-2)" "unprognostic (2.34e-1)" "unprognostic (1.78e-1)" "unprognostic (6.86e-2)" "potential prognostic unfavorable (4.49e-4)" "unprognostic (2.94e-1)" "unprognostic (1.71e-1)" "unprognostic (2.41e-2)" TRERF1 "BCAR2, dJ139D8.5, HSA277276, RAPA, TReP-132" ENSG00000124496 "Transcriptional regulating factor 1" Q96PN7 6 42224931-42452051 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 265.1;Sertoli cells: 540.1" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 540.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts, Skeletal muscle - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2794 "Granulosa cells: 285762.4;T-cells: 273055.5" "Not detected" "Not detected" "HPA027771, HPA051273, HPA059943" Enhanced Enhanced "Nucleoplasm,Nucleoli fibrillar center,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 54: Non-specific - Ribosome" "Cluster 53: Neurons - Mixed function" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 14 Nucleoplasm "Nucleoli fibrillar center, Cytosol" "HPA027771: , HPA051273: , HPA059943: " "unprognostic (6.48e-2)" "unprognostic (2.25e-3)" "unprognostic (4.81e-1)" "unprognostic (1.22e-2)" "unprognostic (3.72e-1)" "unprognostic (3.05e-2)" "unprognostic (7.76e-2)" "potential prognostic favorable (5.53e-5)" "unprognostic (2.16e-3)" "unprognostic (2.35e-3)" "unprognostic (2.53e-2)" "unprognostic (3.06e-1)" "unprognostic (2.87e-2)" "unprognostic (5.57e-3)" "unprognostic (3.96e-2)" "unprognostic (9.20e-2)" "unprognostic (4.00e-1)" "unprognostic (1.04e-1)" "unprognostic (1.05e-1)" "unprognostic (7.84e-3)" "unprognostic (3.27e-2)" "unprognostic (7.51e-2)" "unprognostic (1.35e-1)" "unprognostic (1.07e-2)" "potential prognostic unfavorable (1.87e-5)" "unprognostic (1.41e-1)" "unprognostic (6.98e-2)" "unprognostic (3.63e-2)" "unprognostic (2.12e-1)" TRIB1 "C8FW, GIG2, TRB1" ENSG00000173334 "Tribbles pseudokinase 1" Q96RU8 8 125430358-125438403 "Enzymes, Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 345.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 332.1;Endometrial glandular cells: 280.9;Epididymal basal cells: 416.3;Neutrophils: 771.7;Ocular epithelial cells: 344.8;Plasma cells: 255.2;Urothelial cells: 255.1" "Cell type enhanced" "Detected in many" "Basal cells: 416.3;Neutrophils: 771.7" "Cell type enhanced" "Detected in many" "astrocyte: 16.6;central nervous system macrophage: 30.4;pericyte: 16.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 9.9;neutrophil: 4.7;non-classical monocyte: 3.5;T-reg: 2.8" "Group enriched" "Detected in many" 12 "granulocytes: 9.9;monocytes: 3.5;T-cells: 2.8" "Cancer enhanced" "Detected in all" "Myeloma: 114.7" "Kidney - Macrophages, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA063982 Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 16 "Plasma membrane, Cytosol" "HPA063982: " "unprognostic (9.54e-2)" "unprognostic (1.81e-2)" "unprognostic (4.09e-3)" "unprognostic (4.13e-2)" "unprognostic (4.76e-3)" "unprognostic (2.31e-1)" "unprognostic (1.94e-1)" "unprognostic (2.75e-1)" "unprognostic (2.81e-1)" "unprognostic (5.35e-2)" "unprognostic (2.88e-1)" "unprognostic (1.04e-1)" "unprognostic (1.98e-2)" "unprognostic (8.38e-2)" "unprognostic (6.95e-2)" "unprognostic (2.67e-2)" "unprognostic (2.79e-2)" "potential prognostic unfavorable (4.85e-6)" "unprognostic (1.59e-1)" "unprognostic (1.49e-2)" "unprognostic (2.05e-1)" "unprognostic (1.24e-2)" "unprognostic (1.11e-3)" "unprognostic (6.83e-2)" "unprognostic (1.97e-1)" "unprognostic (4.74e-2)" "unprognostic (5.96e-2)" "unprognostic (1.50e-1)" "unprognostic (4.04e-2)" "unprognostic (4.26e-1)" "unprognostic (1.67e-1)" TRIM32 "BBS11, HT2A, LGMD2H, TATIP" ENSG00000119401 "Tripartite motif containing 32" Q13049 9 116687305-116701300 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Limb-girdle muscular dystrophy, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 26.9;Decidual stromal cells: 28.9;Thymic myoid cells: 35.4" "Cell type enhanced" "Detected in many" "Stromal cells: 35.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myofibers: 5195859.2" "Group enriched" "Detected in many" "cerebral cortex: 2452180.3;lymphoid tissue: 8482348.5" HPA050060 Approved Approved "Intermediate filaments" No No "Cluster 39: T-cells - T-cell receptor" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 5: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 95 "Intermediate filaments" "HPA050060: " "unprognostic (1.31e-1)" "unprognostic (1.31e-2)" "unprognostic (8.91e-2)" "unprognostic (3.52e-3)" "unprognostic (3.49e-2)" "unprognostic (1.67e-1)" "unprognostic (1.99e-1)" "unprognostic (3.32e-2)" "unprognostic (4.59e-3)" "unprognostic (7.14e-3)" "potential prognostic favorable (1.30e-5)" "unprognostic (5.31e-2)" "unprognostic (1.75e-1)" "unprognostic (3.36e-3)" "unprognostic (4.74e-2)" "unprognostic (6.65e-2)" "unprognostic (2.29e-1)" "unprognostic (3.37e-2)" "unprognostic (3.28e-2)" "unprognostic (3.25e-2)" "unprognostic (9.23e-2)" "unprognostic (2.51e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-2)" "unprognostic (6.64e-2)" "unprognostic (3.32e-1)" "unprognostic (3.31e-1)" "unprognostic (3.26e-2)" "unprognostic (2.15e-1)" "unprognostic (2.15e-1)" "unprognostic (1.76e-1)" TRIM45 "FLJ13181, RNF99" ENSG00000134253 "Tripartite motif containing 45" Q9H8W5 1 117111060-117122587 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 27.3" "Cell type enhanced" "Detected in many" "Myonuclei: 24.6" "Cell type enhanced" "Detected in many" "Myocytes: 24.6" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 18.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 15 "Oocytes: 1530.9" "Tissue enriched" "Detected in single" 10455 "intestine: 1045471.7" "HPA030266, HPA054308" Uncertain Supported "Nucleoplasm,Cytokinetic bridge,Cytosol" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 3 Cytosol "Nucleoplasm, Cytokinetic bridge" "HPA030266: , HPA054308: " "unprognostic (9.84e-2)" "unprognostic (1.32e-3)" "unprognostic (3.14e-1)" "unprognostic (2.00e-1)" "unprognostic (4.36e-2)" "unprognostic (1.08e-1)" "unprognostic (9.92e-2)" "potential prognostic favorable (6.37e-4)" "unprognostic (3.13e-1)" "unprognostic (1.15e-2)" "unprognostic (1.99e-1)" "unprognostic (1.86e-1)" "potential prognostic favorable (1.61e-4)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (5.27e-2)" "unprognostic (1.82e-1)" "unprognostic (2.82e-1)" "unprognostic (1.41e-3)" "unprognostic (1.48e-3)" "unprognostic (1.22e-1)" "unprognostic (1.56e-2)" "unprognostic (4.54e-2)" "unprognostic (7.49e-2)" "unprognostic (4.66e-2)" "unprognostic (4.30e-2)" "unprognostic (1.95e-2)" "unprognostic (4.65e-2)" "unprognostic (4.30e-2)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (5.03e-5)" "unprognostic (2.84e-1)" TRIM46 "FLJ23229, TRIFIC" ENSG00000163462 "Tripartite motif containing 46" Q7Z4K8 1 155173787-155184971 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 21.5" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 20.3;Brain inhibitory neurons: 21.0;Breast lactating cells: 20.6;Epicardial cells: 25.0;Epididymal principal cells: 12.5;Late spermatids: 12.5;Oligodendrocytes: 10.7;Other brain neurons: 17.0;Retinal amacrine cells: 20.2;Retinal ganglion cells: 15.5" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 25.0;Neuronal cells: 21.0;Secretory cells: 20.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 9.7" "Adrenal gland - Adrenal medulla cells, Pancreas - Alpha cells, Testis - Early spermatids, Testis - Late spermatids, Thyroid gland - T-cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 65799 "Astrocytes and Neuropil: 3645577.4;Microglia and Neuropil: 6591175.1;Neurons: 9503059.4" "Tissue enriched" "Detected in single" 70724 "cerebral cortex: 7072391.5" "HPA030391, HPA055583" Enhanced Approved "Microtubule ends,Cytokinetic bridge,Mitotic spindle,Primary cilium transition zone,Centrosome,Cytosol" Yes NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 34: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 35: Neurons - Synaptic function & neurogenesis" "Microtubule ends, Mitotic spindle, Primary cilium transition zone" "Cytokinetic bridge, Centrosome, Cytosol" "HPA030391: , HPA055583: " "unprognostic (3.96e-2)" "unprognostic (2.26e-1)" "unprognostic (3.26e-1)" "unprognostic (2.47e-2)" "unprognostic (5.00e-2)" "unprognostic (3.01e-1)" "potential prognostic favorable (4.90e-4)" "unprognostic (9.44e-2)" "unprognostic (3.00e-2)" "unprognostic (1.87e-1)" "unprognostic (1.43e-2)" "unprognostic (3.60e-1)" "unprognostic (3.12e-3)" "unprognostic (9.76e-3)" "unprognostic (8.50e-2)" "unprognostic (6.13e-2)" "unprognostic (1.60e-1)" "unprognostic (4.79e-1)" "unprognostic (2.11e-2)" TRIM68 "FLJ10369, RNF137, SS-56" ENSG00000167333 "Tripartite motif containing 68" Q6AZZ1 11 4598672-4608231 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Respiratory secretory cells: 14.5" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 2098578.4" "Not detected" "Not detected" HPA023455 Uncertain Supported Nucleoplasm,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 33: Thyroid gland - Tissue development" "Cluster 55: Non-specific - Transcription" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 96: Enteroendocrine cells - Neuropeptide signaling" 27 "Nucleoplasm, Cytosol" "HPA023455: " "unprognostic (1.13e-3)" "unprognostic (7.89e-2)" "unprognostic (7.99e-2)" "unprognostic (3.67e-3)" "unprognostic (1.37e-1)" "potential prognostic favorable (2.98e-4)" "unprognostic (2.96e-3)" "unprognostic (3.62e-2)" "unprognostic (8.10e-2)" "unprognostic (5.83e-2)" "potential prognostic favorable (7.46e-4)" "unprognostic (1.07e-2)" "unprognostic (6.51e-3)" "unprognostic (6.75e-2)" "unprognostic (9.55e-2)" "unprognostic (3.53e-2)" "unprognostic (3.54e-1)" "unprognostic (1.13e-2)" "unprognostic (2.47e-1)" "unprognostic (5.64e-2)" "unprognostic (6.72e-2)" "unprognostic (3.19e-2)" "unprognostic (1.44e-1)" "unprognostic (8.60e-2)" "unprognostic (2.58e-2)" "potential prognostic unfavorable (1.30e-4)" "unprognostic (8.49e-2)" "unprognostic (3.82e-2)" "unprognostic (1.65e-1)" "unprognostic (3.00e-1)" "unprognostic (2.60e-1)" TRIM72 MG53 ENSG00000177238 "Tripartite motif containing 72" Q6ZMU5 16 31214091-31231537 "Predicted intracellular proteins, Transporters" "Exocytosis, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 10 "skeletal muscle: 142.2;tongue: 40.2" "Group enriched" "Detected in many" 4 "Myonuclei: 232.6;Thymic myoid cells: 263.8" "Group enriched" "Detected in many" 4 "Myocytes: 232.6;Stromal cells: 263.8" "Cell type enriched" "Detected in some" 4 "upper rhombic lip: 12.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cancer enhanced" "Detected in some" "Myeloma: 12.1;Sarcoma: 8.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Skeletal myofibers: 526463755.6" "Tissue enriched" "Detected in single" 4362932 "skeletal muscle: 436293228.3" HPA054909 Enhanced Approved Nucleoplasm,Vesicles NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 35: Non-specific - DNA binding" "Cluster 33: Sarcoma - Muscle contraction" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 17 Vesicles Nucleoplasm "HPA054909: " "unprognostic (2.55e-1)" "unprognostic (6.81e-2)" "unprognostic (8.16e-2)" "unprognostic (1.18e-1)" "unprognostic (3.92e-2)" "unprognostic (4.66e-1)" "unprognostic (1.95e-1)" "unprognostic (9.78e-3)" "unprognostic (2.71e-1)" "unprognostic (5.49e-2)" "unprognostic (8.69e-2)" "unprognostic (3.76e-2)" "unprognostic (4.85e-2)" "unprognostic (2.02e-1)" "unprognostic (7.83e-2)" TRIO ARHGEF23 ENSG00000038382 "Trio Rho guanine nucleotide exchange factor" O75962 5 14143342-14532128 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 1.4;NK-cell: 1.4" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 13555658.7;Microglia and Neuropil: 18881891.6;Neurons: 14726080.0" "Group enriched" "Detected in many" "cerebral cortex: 12869781.1;intestine: 3997349.8;lymphoid tissue: 3463722.1;Stomach: 5254638.8" "HPA008157, HPA064664" Supported Supported "Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Basal body,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 29: Non-specific - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" 13 Cytosol "Vesicles, Plasma membrane, Primary cilium, Primary cilium tip, Basal body" "HPA008157: , HPA064664: " "unprognostic (3.12e-1)" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (1.75e-2)" "unprognostic (1.72e-1)" "unprognostic (2.32e-2)" "unprognostic (3.05e-2)" "unprognostic (1.00e-1)" "unprognostic (9.19e-2)" "unprognostic (2.41e-1)" "potential prognostic unfavorable (5.10e-6)" "unprognostic (7.71e-3)" "unprognostic (1.63e-1)" "potential prognostic unfavorable (7.86e-5)" "unprognostic (3.62e-1)" "unprognostic (1.70e-1)" "unprognostic (1.16e-2)" "unprognostic (2.80e-1)" "unprognostic (3.20e-2)" "unprognostic (2.53e-1)" "unprognostic (3.11e-2)" "unprognostic (4.31e-1)" "unprognostic (1.75e-3)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "potential prognostic favorable (7.28e-4)" "unprognostic (4.23e-3)" "unprognostic (9.46e-3)" "unprognostic (2.95e-1)" "potential prognostic unfavorable (1.55e-4)" "potential prognostic unfavorable (2.58e-4)" TRIP11 "CEV14, GMAP-210, GMAP210, Trip230" ENSG00000100815 "Thyroid hormone receptor interactor 11" Q15643 14 91965991-92040896 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 56248009.8" "Low tissue specificity" "Detected in many" HPA002570 Supported Supported "Golgi apparatus,Primary cilium" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 8: Non-specific - Secretory pathway" 20 "Golgi apparatus" "Primary cilium" "HPA002570: " "unprognostic (2.49e-1)" "unprognostic (1.47e-1)" "unprognostic (1.42e-1)" "unprognostic (5.19e-3)" "unprognostic (1.18e-1)" "unprognostic (1.18e-1)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "unprognostic (4.67e-2)" "potential prognostic unfavorable (3.91e-4)" "validated prognostic favorable (6.55e-6)" "validated prognostic favorable (8.11e-4)" "unprognostic (3.43e-1)" "unprognostic (1.32e-3)" "unprognostic (5.25e-2)" "unprognostic (4.44e-2)" "unprognostic (1.78e-2)" "unprognostic (6.24e-2)" "unprognostic (1.86e-1)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (3.02e-4)" "unprognostic (2.92e-2)" "unprognostic (2.27e-2)" "unprognostic (1.43e-1)" "unprognostic (3.36e-2)" "unprognostic (2.28e-1)" "unprognostic (1.26e-1)" "unprognostic (2.35e-1)" "unprognostic (3.06e-1)" "unprognostic (2.24e-2)" "unprognostic (3.51e-1)" TRMT10A "MGC27034, RG9MTD2, TRM10" ENSG00000145331 "TRNA methyltransferase 10A" Q8TBZ6 4 99546709-99564039 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Methyltransferase, Transferase" "Diabetes mellitus, Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 113.8;Late primary spermatocytes: 66.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 113.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 246339.2;Granulosa cells: 293359.0" "Not detected" "Not detected" "HPA047601, HPA058241" Uncertain Supported "Nucleoplasm,Nucleoli,Actin filaments,Cytosol" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 3: Early primary spermatocytes - Early meiosis" 2 "Nucleoplasm, Nucleoli, Actin filaments" Cytosol "HPA047601: , HPA058241: " "unprognostic (3.08e-3)" "unprognostic (1.48e-2)" "unprognostic (5.93e-3)" "unprognostic (7.03e-2)" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (1.43e-1)" "unprognostic (1.29e-3)" "validated prognostic favorable (1.24e-4)" "validated prognostic favorable (4.20e-4)" "unprognostic (4.64e-2)" "unprognostic (8.90e-2)" "unprognostic (1.28e-3)" "unprognostic (8.62e-2)" "unprognostic (1.34e-1)" "unprognostic (9.82e-2)" "unprognostic (2.51e-1)" "unprognostic (1.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.32e-1)" "unprognostic (5.02e-2)" "unprognostic (1.39e-1)" "unprognostic (3.42e-1)" "unprognostic (3.16e-2)" "unprognostic (2.14e-1)" "unprognostic (4.28e-2)" "potential prognostic unfavorable (2.80e-5)" "unprognostic (1.20e-2)" TRMT10C "FLJ20432, MRPP1, RG9MTD1" ENSG00000174173 "TRNA methyltransferase 10C, mitochondrial RNase P subunit" Q7L0Y3 3 101561868-101566446 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA036671 Approved Supported Nucleoplasm,Mitochondria NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 15 Mitochondria Nucleoplasm "HPA036671: " "unprognostic (5.32e-2)" "unprognostic (2.41e-2)" "unprognostic (1.41e-2)" "unprognostic (7.10e-2)" "unprognostic (1.49e-2)" "unprognostic (1.53e-2)" "unprognostic (1.83e-1)" "unprognostic (4.21e-2)" "unprognostic (8.52e-2)" "potential prognostic favorable (5.14e-5)" "unprognostic (1.45e-1)" "unprognostic (6.39e-2)" "potential prognostic unfavorable (6.00e-6)" "unprognostic (4.90e-3)" "potential prognostic unfavorable (9.96e-4)" "unprognostic (1.22e-1)" "unprognostic (4.82e-2)" "unprognostic (3.81e-1)" "unprognostic (9.47e-2)" "unprognostic (2.82e-2)" "unprognostic (5.67e-2)" "unprognostic (1.98e-3)" "potential prognostic favorable (2.93e-4)" "unprognostic (1.95e-1)" "unprognostic (1.14e-1)" "unprognostic (6.41e-2)" "unprognostic (2.70e-1)" "unprognostic (2.78e-2)" "unprognostic (4.23e-1)" TRMT11 "C6orf75, dJ187J11.2, MDS024, TRM11, TRMT11-1" ENSG00000066651 "TRNA methyltransferase 11 homolog" Q7Z4G4 6 125986479-126203817 "Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 353.7;Myonuclei: 356.9;Thyrotrophs: 340.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Macrophages: 13493895.2" "Tissue enhanced" "Detected in many" "intestine: 648596.0" HPA030473 Approved "Nuclear bodies" Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 31: Liver - Metabolism & Coagulation" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" 4 "Nuclear bodies" "HPA030473: " "unprognostic (2.02e-1)" "unprognostic (3.09e-2)" "unprognostic (3.39e-1)" "unprognostic (2.14e-2)" "unprognostic (6.35e-3)" "unprognostic (3.51e-1)" "unprognostic (1.29e-1)" "unprognostic (1.14e-3)" "unprognostic (4.25e-1)" "unprognostic (9.68e-2)" "unprognostic (1.23e-1)" "unprognostic (3.45e-2)" "unprognostic (5.25e-2)" "unprognostic (1.18e-1)" "unprognostic (4.42e-1)" "unprognostic (3.57e-3)" "unprognostic (2.79e-3)" "unprognostic (1.49e-1)" "unprognostic (6.35e-2)" "unprognostic (1.81e-1)" "unprognostic (9.16e-2)" "unprognostic (3.09e-2)" "unprognostic (2.14e-2)" "unprognostic (1.26e-1)" "unprognostic (8.86e-2)" "unprognostic (9.22e-3)" "unprognostic (2.22e-2)" "unprognostic (2.02e-1)" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.96e-1)" TRMT12 "FLJ20772, Trm12, TYW2" ENSG00000183665 "TRNA methyltransferase 12 homolog" Q53H54 8 124450820-124462150 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 36.4" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 36.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA023939 Approved Approved Nucleoplasm,Mitochondria No No "Cluster 33: Non-specific - ATP binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 29: Forebrain - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 20: Non-specific - Transcription regulation" 2 Nucleoplasm Mitochondria "HPA023939: " "unprognostic (6.04e-2)" "unprognostic (9.15e-3)" "unprognostic (4.54e-2)" "unprognostic (1.46e-1)" "unprognostic (4.96e-2)" "unprognostic (2.85e-3)" "unprognostic (7.12e-2)" "unprognostic (1.04e-3)" "potential prognostic unfavorable (2.54e-5)" "unprognostic (8.56e-2)" "potential prognostic favorable (8.65e-6)" "unprognostic (2.50e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (5.30e-4)" "unprognostic (1.34e-2)" "unprognostic (2.12e-2)" "unprognostic (9.20e-3)" "unprognostic (2.70e-1)" "unprognostic (2.18e-2)" "unprognostic (3.24e-2)" "unprognostic (2.12e-1)" "unprognostic (1.27e-1)" "unprognostic (8.11e-2)" "unprognostic (9.43e-2)" "unprognostic (1.45e-2)" "unprognostic (1.65e-1)" "unprognostic (1.76e-1)" "unprognostic (2.18e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-2)" "unprognostic (1.05e-1)" TRMT1L C1orf25 ENSG00000121486 "TRNA methyltransferase 1 like" Q7Z2T5 1 185118101-185157072 "Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 166.8" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 166.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA026728, HPA054464" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 39: Testis - Nuclear processes" "Cluster 55: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 46 Nucleoplasm Nucleoli "HPA026728: , HPA054464: " "unprognostic (3.72e-1)" "unprognostic (1.05e-2)" "unprognostic (2.18e-1)" "unprognostic (8.62e-2)" "unprognostic (2.55e-1)" "unprognostic (2.06e-1)" "unprognostic (1.50e-2)" "unprognostic (1.25e-1)" "potential prognostic unfavorable (8.97e-4)" "potential prognostic favorable (3.84e-8)" "unprognostic (5.12e-3)" "unprognostic (9.75e-2)" "unprognostic (7.22e-2)" "unprognostic (4.49e-2)" "unprognostic (1.71e-1)" "unprognostic (1.10e-1)" "unprognostic (1.98e-1)" "unprognostic (1.85e-1)" "unprognostic (1.16e-1)" "unprognostic (2.71e-3)" "unprognostic (2.13e-1)" "unprognostic (1.05e-1)" "unprognostic (4.24e-2)" "unprognostic (2.35e-2)" "unprognostic (1.90e-1)" "unprognostic (6.92e-2)" "unprognostic (9.37e-2)" "unprognostic (1.62e-1)" "unprognostic (1.77e-2)" "unprognostic (1.92e-1)" TRMU "FLJ10140, MTO2, MTU1, TRMT" ENSG00000100416 "TRNA mitochondrial 2-thiouridylase" O75648 22 46330875-46357340 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "RNA-binding, Transferase, tRNA-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 6511965.9" "Tissue enhanced" "Detected in some" "lymphoid tissue: 475218.9" "HPA000824, HPA035273, HPA043300" Uncertain Supported Mitochondria NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 70: Non-specific - Protein processing" "Cluster 45: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 Mitochondria "HPA000824: , HPA035273: , HPA043300: " "unprognostic (1.28e-1)" "unprognostic (3.50e-3)" "unprognostic (2.39e-1)" "unprognostic (8.89e-2)" "unprognostic (4.44e-3)" "unprognostic (3.84e-2)" "unprognostic (2.52e-1)" "unprognostic (2.92e-2)" "unprognostic (2.40e-1)" "unprognostic (2.82e-2)" "potential prognostic favorable (6.22e-4)" "unprognostic (4.69e-2)" "unprognostic (3.97e-2)" "potential prognostic unfavorable (8.50e-7)" "unprognostic (2.31e-2)" "unprognostic (9.27e-3)" "unprognostic (5.09e-2)" "unprognostic (1.91e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (2.80e-3)" "unprognostic (1.18e-3)" "unprognostic (1.30e-3)" "unprognostic (1.62e-1)" "unprognostic (2.60e-2)" "unprognostic (1.38e-3)" "unprognostic (3.07e-2)" "unprognostic (8.31e-3)" "unprognostic (9.20e-2)" "unprognostic (4.08e-1)" "unprognostic (1.26e-2)" TRNT1 "CCA1, CGI-47, MtCCA" ENSG00000072756 "TRNA nucleotidyl transferase 1" Q96Q11 3 3126933-3153435 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Nucleotidyltransferase, RNA-binding, Transferase" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA036938 Uncertain Supported Mitochondria Yes No "Cluster 41: Basophils - Unknown function" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Mitochondria "HPA036938: " "unprognostic (1.15e-1)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (1.37e-2)" "unprognostic (1.07e-2)" "unprognostic (1.30e-2)" "unprognostic (1.78e-1)" "unprognostic (3.72e-2)" "unprognostic (1.09e-1)" "unprognostic (2.09e-2)" "potential prognostic favorable (1.08e-5)" "unprognostic (2.09e-1)" "unprognostic (9.88e-2)" "unprognostic (3.36e-3)" "unprognostic (4.54e-2)" "unprognostic (2.95e-2)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (1.97e-1)" "unprognostic (3.00e-2)" "unprognostic (3.86e-2)" "potential prognostic unfavorable (5.73e-4)" "unprognostic (6.42e-3)" "unprognostic (8.87e-2)" "unprognostic (1.67e-1)" "potential prognostic favorable (1.31e-5)" "unprognostic (5.78e-2)" "unprognostic (1.43e-1)" "unprognostic (2.42e-1)" "unprognostic (3.97e-1)" "unprognostic (1.73e-1)" TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686797 "Disease related genes, Enzymes, Essential proteins, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "parathyroid gland: 102.5" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 833.5;Choroid plexus epithelial cells: 504.9;Distal convoluted tubule cells: 2550.7;Retinal pigment epithelial cells: 763.1" "Cell type enhanced" "Detected in all" "Myocytes: 833.5;Pigment cells: 763.1;Renal nephron cells: 2550.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 39684 "Distal tubules: 4127323.6;Large ducts: 3809400.5" "Not detected" "Not detected" "HPA035522, HPA052173" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 11 "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA035522: , HPA052173: " "unprognostic (5.36e-2)" "unprognostic (5.19e-2)" "unprognostic (2.05e-1)" "unprognostic (4.12e-2)" "unprognostic (5.77e-2)" "unprognostic (3.61e-1)" "unprognostic (1.49e-1)" "unprognostic (2.28e-1)" "unprognostic (5.51e-2)" "unprognostic (2.17e-3)" "potential prognostic favorable (4.75e-4)" "unprognostic (2.20e-2)" "unprognostic (1.37e-1)" "unprognostic (3.34e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (8.81e-2)" "unprognostic (2.28e-1)" "unprognostic (1.20e-2)" "unprognostic (6.87e-2)" "unprognostic (1.96e-1)" "unprognostic (3.79e-1)" "unprognostic (9.83e-3)" "unprognostic (4.01e-2)" "unprognostic (2.38e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-3)" "unprognostic (1.52e-1)" "unprognostic (2.17e-1)" "unprognostic (4.70e-3)" "unprognostic (1.20e-1)" TRPS1 "GC79, LGCR" ENSG00000104447 "Transcriptional repressor GATA binding 1" Q9UHF7 8 115408496-115809673 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "breast: 56.9" "Cell type enhanced" "Detected in many" "Adipocytes: 951.9;Astrocytes: 1204.8;Bergmann glia: 1533.6;Breast hormone-responsive cells: 1683.2;Breast secretory cells: 1051.5;Ependymal cells: 1106.5" "Cell type enhanced" "Detected in many" "Glial cells: 1533.6;Luminal cells: 1683.2" "Low cell type specificity" "Detected in all" "Cancer enriched" "Detected in many" 7 "Breast Invasive Carcinoma (TCGA): 108.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 4.5" "Low lineage specificity" "Detected in many" "Cancer enriched" "Detected in many" 4 "breast cancer: 67.7" "Heart muscle - Fibroblasts, Prostate - Fibroblasts, Skeletal muscle - Fibroblasts, Skin - Outer root sheath cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 42262.2;Smooth muscle cells: 20029.4" "Not detected" "Not detected" "HPA060380, HPA071767" Enhanced Supported Nucleoplasm NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 39: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 30 Nucleoplasm "HPA060380: , HPA071767: " "unprognostic (1.23e-1)" "unprognostic (4.40e-2)" "unprognostic (1.41e-1)" "unprognostic (6.79e-3)" "unprognostic (4.03e-2)" "unprognostic (3.24e-2)" "unprognostic (2.63e-1)" "unprognostic (5.24e-1)" "unprognostic (1.48e-3)" "unprognostic (3.54e-3)" "unprognostic (5.06e-2)" "unprognostic (2.37e-1)" "unprognostic (4.20e-2)" "unprognostic (4.03e-1)" "unprognostic (6.88e-2)" "unprognostic (5.89e-2)" "unprognostic (1.47e-1)" "unprognostic (1.45e-1)" "unprognostic (7.01e-2)" "unprognostic (2.68e-3)" "validated prognostic unfavorable (2.72e-5)" "validated prognostic unfavorable (1.79e-4)" "unprognostic (5.55e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-2)" "unprognostic (1.99e-1)" "unprognostic (8.74e-2)" "unprognostic (1.12e-1)" "unprognostic (4.66e-3)" "unprognostic (2.49e-1)" TRUB1 PUS4 ENSG00000165832 "TruB pseudouridine synthase family member 1" Q8WWH5 10 114938195-114977676 "Enzymes, Predicted intracellular proteins" "mRNA processing, tRNA processing" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 75.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 13527931.5" "Group enriched" "Detected in many" "cerebral cortex: 1037479.3;intestine: 2883724.7" "HPA037914, HPA057552" Approved Approved Vesicles NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 18: Adrenal cortex cells - Steroidogensis" 5 Vesicles "HPA037914: , HPA057552: " "unprognostic (6.82e-2)" "unprognostic (6.23e-2)" "unprognostic (8.44e-2)" "unprognostic (5.79e-2)" "unprognostic (3.24e-2)" "unprognostic (2.73e-1)" "unprognostic (1.01e-2)" "unprognostic (2.86e-3)" "unprognostic (2.62e-1)" "unprognostic (6.17e-2)" "potential prognostic favorable (5.66e-6)" "unprognostic (8.15e-2)" "unprognostic (6.48e-2)" "unprognostic (2.13e-2)" "unprognostic (2.25e-1)" "unprognostic (2.67e-2)" "unprognostic (2.01e-1)" "unprognostic (3.84e-3)" "unprognostic (1.49e-1)" "unprognostic (2.69e-1)" "unprognostic (3.59e-3)" "unprognostic (2.92e-2)" "unprognostic (6.92e-2)" "unprognostic (3.74e-2)" "unprognostic (5.13e-3)" "unprognostic (3.95e-1)" "unprognostic (2.13e-1)" "unprognostic (2.49e-2)" "unprognostic (2.33e-1)" "unprognostic (1.07e-1)" "unprognostic (1.93e-1)" TSC1 "hamartin, KIAA0243, LAM, TSC" ENSG00000165699 "TSC complex subunit 1" Q92574 9 132891348-132946874 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Cancer-related genes, Disease variant, Epilepsy, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 244.9;Late spermatids: 764.5" "Cell type enriched" "Detected in all" 6 "Spermatogenic cell types: 764.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "cerebral cortex: 2327260.9;lymphoid tissue: 2368707.4" "CAB011568, CAB012481, HPA074132" Supported Supported "Lipid droplets,Primary cilium transition zone,Basal body,Cytosol" NA NA "Cluster 19: Eosinophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 62 Cytosol "Lipid droplets, Primary cilium transition zone, Basal body" "CAB011568: , CAB012481: , HPA074132: " "unprognostic (1.88e-2)" "unprognostic (1.10e-2)" "unprognostic (2.34e-1)" "unprognostic (5.36e-2)" "unprognostic (1.41e-1)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (2.68e-1)" "potential prognostic favorable (9.62e-4)" "unprognostic (3.42e-1)" "unprognostic (1.67e-1)" "validated prognostic favorable (4.30e-7)" "validated prognostic favorable (8.97e-6)" "unprognostic (2.07e-1)" "unprognostic (2.70e-3)" "unprognostic (8.87e-2)" "unprognostic (1.59e-1)" "unprognostic (8.72e-2)" "unprognostic (5.82e-2)" "unprognostic (3.64e-3)" "unprognostic (4.86e-2)" "unprognostic (2.13e-1)" "unprognostic (5.58e-2)" "unprognostic (1.72e-2)" "unprognostic (2.62e-1)" "unprognostic (8.58e-3)" "unprognostic (3.62e-2)" "unprognostic (1.56e-2)" "unprognostic (1.95e-2)" "unprognostic (2.84e-1)" "unprognostic (3.51e-2)" "unprognostic (4.77e-2)" TSHZ3 "KIAA1474, TSH3, ZNF537" ENSG00000121297 "Teashirt zinc finger homeobox 3" Q63HK5 19 31149979-31349436 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 31.7" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Decidual stromal cells: 130.7;Endometrial stromal cells: 208.8;Lactotrophs: 182.1;Leydig cells: 133.7;Myosatellite cells: 177.7;Ovarian stromal cells: 136.2;Podocytes: 120.8;Retinal bipolar cells: 114.5;Somatotrophs: 114.9" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 191.5;Stromal cells: 208.8" "Cell type enhanced" "Detected in all" "deep-layer near-projecting: 246.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Bone cancer: 21.1;Sarcoma: 13.6" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Adrenal gland - Fibroblasts, Heart muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1844 "Neurons: 184437.8" "Tissue enriched" "Detected in single" 90 "ovary: 9038.1" "HPA008834, HPA071010" Approved Enhanced "Nucleoplasm,Plasma membrane" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 53: Neurons - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" 27 Nucleoplasm "Plasma membrane" "HPA008834: , HPA071010: " "unprognostic (1.39e-2)" "unprognostic (2.84e-1)" "unprognostic (2.12e-1)" "unprognostic (1.07e-1)" "unprognostic (2.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (6.58e-4)" "unprognostic (4.93e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-1)" "unprognostic (1.27e-1)" "unprognostic (4.47e-2)" "unprognostic (3.40e-2)" "unprognostic (2.73e-1)" "unprognostic (1.97e-3)" "unprognostic (1.73e-1)" "unprognostic (2.08e-1)" "potential prognostic unfavorable (5.27e-4)" "unprognostic (1.40e-1)" "unprognostic (6.74e-2)" "unprognostic (2.08e-1)" "unprognostic (1.30e-2)" "unprognostic (1.77e-1)" "unprognostic (2.97e-2)" "unprognostic (2.17e-1)" "unprognostic (1.04e-2)" "unprognostic (8.37e-2)" "unprognostic (9.59e-3)" "unprognostic (8.87e-2)" TSLP ENSG00000145777 "Thymic stromal lymphopoietin" Q969D9 5 111070062-111078026 "FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" Cytokine "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 10.8;urinary bladder: 11.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 43.3;Breast secretory cells: 13.6;Early spermatids: 45.5;Esophageal basal cells: 34.1;Fibroblasts: 25.3;Late spermatids: 38.8;Ocular epithelial cells: 17.8;Pericytes: 36.8;Respiratory basal cells: 21.7;Suprabasal keratinocytes: 17.0" "Cell type enhanced" "Detected in many" "Basal cells: 43.3;Fibroblasts: 25.3;Mural cells: 36.8;Spermatogenic cell types: 45.5" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.3;fibroblast: 3.2;pericyte: 4.1;vascular associated smooth muscle cell: 2.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "thalamus: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes, Stomach - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056350 Uncertain "Golgi apparatus,Vesicles" "Secreted to blood" Cytokine NA NA 38400 "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 39: Astrocytes - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 17: Non-specific - RNA processing" "Golgi apparatus, Vesicles" "HPA056350: " "unprognostic (2.00e-1)" "unprognostic (3.84e-1)" "unprognostic (2.14e-1)" "unprognostic (6.83e-3)" "unprognostic (1.34e-1)" "unprognostic (4.59e-3)" "potential prognostic favorable (1.34e-4)" "unprognostic (9.35e-3)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "unprognostic (5.25e-2)" "unprognostic (9.30e-2)" TSNARE1 FLJ31164 ENSG00000171045 "T-SNARE domain containing 1" Q96NA8 8 142212080-142403182 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA074249 Approved Approved Cytosol NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 3 Cytosol "HPA074249: " "unprognostic (1.08e-1)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.09e-2)" "unprognostic (5.59e-2)" "unprognostic (3.39e-1)" "unprognostic (9.15e-2)" "unprognostic (1.09e-3)" "unprognostic (2.46e-3)" "unprognostic (1.58e-1)" "unprognostic (8.54e-3)" "unprognostic (1.90e-2)" "unprognostic (5.17e-2)" "unprognostic (2.41e-3)" "unprognostic (3.97e-2)" "potential prognostic favorable (1.48e-5)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (8.56e-2)" "unprognostic (1.78e-2)" "unprognostic (4.62e-2)" "unprognostic (3.57e-2)" "unprognostic (1.59e-2)" "unprognostic (3.30e-1)" "unprognostic (3.79e-3)" "unprognostic (4.90e-2)" "unprognostic (1.45e-1)" "unprognostic (2.52e-1)" "unprognostic (6.05e-3)" "unprognostic (2.68e-1)" TSNAX "C3PO, TRAX" ENSG00000116918 "Translin associated factor X" Q99598 1 231528541-231566524 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Astrocytes: 29.0;Bergmann glia: 36.6;Brain excitatory neurons: 38.6;Brain inhibitory neurons: 34.8;Choroid plexus epithelial cells: 58.7;Ependymal cells: 36.3;Microglia: 81.9;Oligodendrocyte progenitor cells: 36.0;Oligodendrocytes: 55.4;Other brain neurons: 40.7" "Group enriched" "Detected in many" 12 "Ciliated cells: 58.7;Glial cells: 81.9;Neuronal cells: 40.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 194.6" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA024613, HPA031054, HPA031055, CAB034263" Approved Enhanced "Nucleoplasm,Golgi apparatus,Cytosol" NA NA 21000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 45: Non-specific - Nuclear processes" "Cluster 22: Non-specific - Basic cellular functions" 52 Nucleoplasm "Golgi apparatus, Cytosol" "CAB034263: , HPA024613: , HPA031054: , HPA031055: " "unprognostic (1.67e-1)" "unprognostic (2.87e-2)" "unprognostic (9.89e-3)" "unprognostic (9.91e-3)" "unprognostic (2.03e-1)" "unprognostic (4.77e-2)" "unprognostic (2.66e-1)" "unprognostic (1.97e-1)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (2.77e-4)" "potential prognostic favorable (7.95e-7)" "unprognostic (5.63e-2)" "unprognostic (8.76e-2)" "unprognostic (1.63e-2)" "unprognostic (1.15e-1)" "unprognostic (1.98e-1)" "unprognostic (2.85e-1)" "unprognostic (1.29e-1)" "unprognostic (3.48e-2)" "unprognostic (2.44e-1)" "potential prognostic unfavorable (9.38e-5)" "unprognostic (1.98e-1)" "unprognostic (9.61e-2)" "unprognostic (9.89e-2)" "unprognostic (1.25e-1)" "unprognostic (1.65e-2)" "unprognostic (1.12e-1)" "unprognostic (1.52e-1)" "unprognostic (1.94e-1)" "unprognostic (4.76e-3)" "unprognostic (7.81e-2)" TSPAN14 "DC-TM4F2, MGC11352, TM4SF14" ENSG00000108219 "Tetraspanin 14" Q8NG11 10 80454265-80533124 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 310.5;Kupffer cells: 299.3;Neutrophils: 322.5;Prostatic hillock cells: 245.5" "Low cell type specificity" "Detected in all" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 208.3;endothelial cell: 234.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Adipocytes (Breast), Heart muscle - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 1874878.5" "Tissue enhanced" "Detected in many" "bone marrow: 3030620.6" "HPA014773, HPA057174" Uncertain Supported Vesicles NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 2 Vesicles "HPA014773: , HPA057174: " "unprognostic (3.16e-2)" "unprognostic (7.69e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-1)" "unprognostic (5.04e-1)" "unprognostic (7.79e-2)" "unprognostic (6.33e-2)" "unprognostic (1.29e-2)" "unprognostic (2.73e-1)" "unprognostic (5.17e-2)" "potential prognostic favorable (1.14e-6)" "unprognostic (9.29e-3)" "unprognostic (3.81e-3)" "unprognostic (1.77e-2)" "unprognostic (3.92e-1)" "unprognostic (2.11e-1)" "unprognostic (6.92e-2)" "unprognostic (1.52e-1)" "unprognostic (8.29e-2)" "unprognostic (1.29e-1)" "unprognostic (1.30e-1)" "unprognostic (3.40e-3)" "unprognostic (8.98e-3)" "unprognostic (4.41e-2)" "unprognostic (1.62e-1)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (1.54e-1)" "unprognostic (3.00e-1)" "unprognostic (8.18e-2)" "unprognostic (1.49e-1)" TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 98.0" "Cell type enhanced" "Detected in many" "Adipocytes: 123.4;Alveolar cells type 1: 145.7;Colonocytes: 127.4;Foveolar cells: 149.3;Oligodendrocytes: 134.7;Urothelial cells: 230.1" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 230.1" "Cell type enhanced" "Detected in many" "committed oligodendrocyte precursor: 110.3;oligodendrocyte: 150.6;upper rhombic lip: 71.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 7325545.5;Collecting ducts: 6056886.2" "Group enriched" "Detected in many" "cerebral cortex: 1126767.4;fallopian tube: 760966.7;intestine: 901810.3;lung: 2618221.4" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: T-cells - Unknown function" "Cluster 74: Non-specific - Signal transduction" "Cluster 30: White matter - Myelination" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 69: Urothelial cells - Basic cellular functions" 131 "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: , HPA071160: " "unprognostic (1.90e-1)" "unprognostic (2.36e-1)" "unprognostic (1.64e-1)" "unprognostic (1.97e-2)" "unprognostic (2.09e-1)" "unprognostic (6.78e-2)" "unprognostic (1.59e-1)" "unprognostic (1.13e-2)" "unprognostic (2.33e-2)" "unprognostic (1.89e-1)" "unprognostic (2.67e-2)" "unprognostic (3.52e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (2.83e-4)" "unprognostic (3.51e-1)" "unprognostic (1.81e-1)" "unprognostic (4.90e-2)" "unprognostic (8.90e-2)" "unprognostic (2.65e-1)" "unprognostic (1.70e-1)" "unprognostic (6.96e-3)" "unprognostic (9.42e-3)" "unprognostic (7.96e-2)" "unprognostic (1.40e-1)" "unprognostic (3.47e-2)" "unprognostic (1.88e-3)" "unprognostic (7.41e-2)" "unprognostic (2.98e-2)" "unprognostic (4.88e-2)" "unprognostic (7.34e-3)" "unprognostic (1.01e-1)" TSPAN31 SAS ENSG00000135452 "Tetraspanin 31" Q12999 12 57738013-57750219 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 187.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 37 "Neurons: 3734.4" "Not detected" "Not detected" "HPA030758, HPA057489" Approved Approved "Nucleoplasm,Golgi apparatus,Cytokinetic bridge,Cytosol" Yes No "Cluster 29: Non-specific - Unknown function" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 21: Non-specific - Metabolism" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 5 "Golgi apparatus" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA030758: , HPA057489: " "unprognostic (6.14e-2)" "potential prognostic unfavorable (4.56e-4)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (7.92e-5)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (3.39e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (4.96e-4)" "unprognostic (1.27e-1)" "potential prognostic favorable (3.52e-7)" "unprognostic (7.32e-3)" "unprognostic (2.19e-1)" "unprognostic (2.56e-1)" "unprognostic (2.34e-1)" "unprognostic (1.71e-1)" "unprognostic (3.31e-1)" "unprognostic (1.29e-1)" "unprognostic (3.93e-2)" "unprognostic (2.06e-1)" "unprognostic (2.83e-3)" "unprognostic (2.60e-1)" "unprognostic (1.11e-1)" "unprognostic (2.81e-1)" "unprognostic (8.68e-2)" "unprognostic (7.42e-2)" "unprognostic (2.16e-2)" "unprognostic (1.49e-1)" "unprognostic (7.38e-2)" "unprognostic (3.47e-2)" "unprognostic (4.94e-3)" TSPAN32 "PHEMX, TSSC6" ENSG00000064201 "Tetraspanin 32" Q96QS1 11 2301997-2318204 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "bone marrow: 18.8;heart muscle: 10.7;lymphoid tissue: 5.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 36.9;cDC: 37.6;Hematopoietic stem cells: 58.7;Innate lymphoid cells: 37.0;Mast cells: 27.7;Megakaryocyte progenitors: 85.4;Megakaryocyte-Erythroid progenitors: 59.3;Megakaryocytes: 43.3;Neutrophil progenitors: 24.1;NK-cells: 54.8;Platelets: 115.6;T-cells: 25.7" "Cell type enhanced" "Detected in many" "Megakaryocytes: 85.4;NK-cells: 54.8;Platelets: 115.6;Stem cells: 58.7" "Cell type enriched" "Detected in some" 12 "leukocyte: 51.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enriched" "Detected in some" 6 "Leukemia: 9.0" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Breast - T-cells, Heart muscle - Cardiomyocytes, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA024135 Uncertain Approved Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" Nucleoplasm "HPA024135: " "unprognostic (2.98e-2)" "unprognostic (1.90e-1)" "unprognostic (1.53e-3)" "unprognostic (1.55e-2)" "unprognostic (1.06e-1)" TSPAN6 "T245, TM4SF6, TSPAN-6" ENSG00000000003 "Tetraspanin 6" O43657 X 100627108-100639991 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Esophageal apical cells: 1280.5;Late spermatids: 3513.3" "Group enriched" "Detected in many" 8 "Apical squamous epithelial cells: 1280.5;Spermatogenic cell types: 3513.3" "Cell type enhanced" "Detected in many" "astrocyte: 32.6;ependymal cell: 58.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 7 "T-cells: 2.1" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Fibroblasts, Liver - Hepatocytes, Testis - Late spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 317934.3;Pancreatic islets: 603101.4" "Tissue enriched" "Detected in some" "intestine: 239435.6" HPA004109 Approved Approved "Nucleoli fibrillar center,Cell Junctions,Cytosol" NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 2 "Cell Junctions, Cytosol" "Nucleoli fibrillar center" "HPA004109: " "unprognostic (1.78e-1)" "unprognostic (1.74e-1)" "unprognostic (2.68e-1)" "unprognostic (4.04e-1)" "unprognostic (4.71e-2)" "unprognostic (6.70e-3)" "unprognostic (3.91e-2)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (6.78e-2)" "potential prognostic favorable (5.30e-6)" "unprognostic (1.79e-2)" "unprognostic (9.46e-3)" "unprognostic (1.41e-1)" "unprognostic (2.82e-2)" "unprognostic (7.08e-2)" "unprognostic (6.58e-3)" "unprognostic (2.60e-2)" "unprognostic (1.14e-1)" "unprognostic (5.66e-2)" "unprognostic (5.14e-1)" "potential prognostic unfavorable (1.14e-4)" "unprognostic (1.26e-2)" "unprognostic (4.08e-2)" "unprognostic (7.25e-3)" "unprognostic (2.15e-2)" "unprognostic (2.03e-2)" "unprognostic (9.82e-2)" "unprognostic (1.64e-1)" "unprognostic (7.15e-2)" "unprognostic (2.41e-1)" TSPO "BZRP, DBI, IBP, MBR, mDRC, PBR, pk18, PKBS, TSPO1" ENSG00000100300 "Translocator protein" P30536 22 43151547-43163242 "Cancer-related genes, FDA approved drug targets, Predicted membrane proteins" "Lipid transport, Transport" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 704.4" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 4707.1;Esophageal basal cells: 1663.5;Esophageal suprabasal cells: 3416.7;Neutrophil progenitors: 1082.3;Neutrophils: 1551.8;Suprabasal keratinocytes: 1288.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 4707.1;Suprabasal cells: 3416.7" "Cell type enhanced" "Detected in many" "leukocyte: 74.0;vascular associated smooth muscle cell: 64.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose visceral - Adipocytes (Visceral), Liver - Vascular endothelial cells, Lung - Macrophages, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 30027605.0" "Low tissue specificity" "Detected in all" "CAB011232, HPA046260, HPA072304" Uncertain Supported Vesicles,Mitochondria,Cytosol NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 66: Non-specific - Mitochondria" "Cluster 85: Squamous epithelial cells - Keratinization" 18 Mitochondria "Vesicles, Cytosol" "CAB011232: , HPA046260: , HPA072304: " "unprognostic (1.76e-1)" "unprognostic (7.80e-2)" "unprognostic (2.07e-2)" "unprognostic (1.71e-1)" "unprognostic (5.26e-2)" "unprognostic (4.34e-2)" "unprognostic (2.56e-1)" "unprognostic (4.50e-2)" "unprognostic (3.36e-2)" "unprognostic (6.89e-2)" "unprognostic (2.46e-3)" "unprognostic (6.77e-3)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (1.36e-5)" "unprognostic (4.74e-3)" "unprognostic (2.11e-1)" "unprognostic (1.00e-1)" "unprognostic (1.49e-1)" "unprognostic (2.62e-1)" "unprognostic (5.65e-2)" "unprognostic (3.22e-2)" "unprognostic (1.87e-3)" "unprognostic (1.46e-1)" "unprognostic (1.41e-1)" "unprognostic (1.74e-1)" "unprognostic (2.61e-1)" "unprognostic (2.77e-1)" "unprognostic (6.10e-3)" "unprognostic (1.78e-1)" "unprognostic (1.78e-1)" "unprognostic (5.67e-2)" TSPYL1 TSPYL ENSG00000189241 "TSPY like 1" Q9H0U9 6 116267760-116279930 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Parietal cells: 305.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Mesothelial cells, Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Neurons: 4772999.5;Neutrophils: 5652722.4" "Tissue enriched" "Detected in many" "lymphoid tissue: 2773045.6" HPA031970 Supported Supported Nucleoplasm,Nucleoli No No "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 97: Non-specific - Cellular respiration" 37 "Nucleoplasm, Nucleoli" "HPA031970: " "unprognostic (1.41e-2)" "unprognostic (6.41e-3)" "unprognostic (3.03e-2)" "unprognostic (2.36e-2)" "unprognostic (1.42e-2)" "unprognostic (8.07e-2)" "unprognostic (1.99e-1)" "unprognostic (3.29e-3)" "unprognostic (2.59e-2)" "unprognostic (5.63e-2)" "validated prognostic favorable (9.45e-11)" "validated prognostic favorable (8.23e-6)" "unprognostic (7.44e-3)" "unprognostic (3.06e-1)" "unprognostic (7.42e-2)" "unprognostic (1.77e-2)" "unprognostic (6.79e-2)" "unprognostic (9.05e-2)" "unprognostic (2.58e-2)" "unprognostic (9.51e-3)" "unprognostic (1.27e-1)" "unprognostic (6.12e-3)" "unprognostic (8.93e-2)" "unprognostic (1.26e-1)" "unprognostic (3.52e-1)" "unprognostic (3.33e-2)" "unprognostic (3.56e-1)" "unprognostic (5.90e-2)" "unprognostic (3.85e-1)" "unprognostic (2.58e-1)" "unprognostic (2.67e-2)" TSPYL5 KIAA1750 ENSG00000180543 "TSPY like 5" Q86VY4 8 97273488-97277928 "Predicted intracellular proteins" "Growth regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 41.8" "Group enriched" "Detected in many" 8 "Early spermatids: 212.4;Late spermatids: 783.4" "Cell type enriched" "Detected in many" 26 "Spermatogenic cell types: 783.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 32.4" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 3920153.5" "Tissue enhanced" "Detected in many" "intestine: 705214.2" HPA031347 Enhanced Approved "Golgi apparatus,Cytosol" No No 8800 "Cluster 21: Testis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 7 Cytosol "Golgi apparatus" "HPA031347: " "unprognostic (4.88e-2)" "unprognostic (2.07e-3)" "unprognostic (5.85e-2)" "unprognostic (6.41e-2)" "unprognostic (3.02e-2)" "unprognostic (1.26e-1)" "unprognostic (1.77e-1)" "unprognostic (2.17e-1)" "unprognostic (1.82e-1)" "potential prognostic favorable (7.30e-5)" "potential prognostic favorable (6.02e-4)" "unprognostic (5.82e-2)" "unprognostic (2.52e-1)" "unprognostic (2.48e-1)" "unprognostic (2.22e-1)" "unprognostic (6.67e-2)" "unprognostic (2.21e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.89e-2)" "unprognostic (3.84e-2)" "unprognostic (1.97e-1)" "unprognostic (3.66e-2)" "unprognostic (1.61e-2)" "unprognostic (2.15e-1)" "unprognostic (2.34e-2)" "unprognostic (1.72e-2)" "unprognostic (1.39e-1)" "unprognostic (1.65e-1)" TSSK1B "FKSG81, SPOGA4, STK22D, TSSK1" ENSG00000212122 "Testis specific serine kinase 1B" Q9BXA7 5 113432553-113434989 "Enzymes, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 230 "testis: 51.7" "Group enriched" "Detected in some" 5 "Early spermatids: 2.9;Late spermatids: 9.6" "Cell type enriched" "Detected in single" 28 "Spermatogenic cell types: 9.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" HPA027827 Enhanced Approved "Nuclear bodies,Centrosome,Basal body,Perinuclear theca,Principal piece,End piece,Annulus" NA NA "Cluster 23: Testis - Spermatogenesis" "Cluster 61: BICR 18 - Protein kinases" "Cluster 90: Elongating spermatids - Spermiogenesis: Elongation" 8 "Nuclear bodies, Principal piece" "Centrosome, Basal body, Perinuclear theca, End piece, Annulus" "HPA027827: " TSSK3 "SPOGA3, STK22C" ENSG00000162526 "Testis specific serine kinase 3" Q96PN8 1 32351521-32364312 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 12.0;testis: 42.4" "Cell type enriched" "Detected in many" 6 "Late spermatids: 2410.1" "Cell type enriched" "Detected in many" 35 "Spermatogenic cell types: 2410.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA037516 Approved "Nucleoplasm,Nucleoli,Nuclear bodies" NA NA "Cluster 47: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 51 "Nucleoplasm, Nucleoli" "Nuclear bodies" "HPA037516: " "unprognostic (1.44e-1)" "unprognostic (2.10e-1)" "unprognostic (1.75e-1)" "unprognostic (2.87e-3)" "unprognostic (7.45e-2)" "unprognostic (8.46e-2)" "unprognostic (5.76e-2)" "potential prognostic unfavorable (6.31e-4)" "unprognostic (1.59e-2)" "unprognostic (4.45e-1)" "unprognostic (1.59e-2)" "unprognostic (1.98e-2)" "unprognostic (3.48e-3)" "unprognostic (6.71e-2)" "unprognostic (2.65e-2)" "unprognostic (4.74e-3)" "unprognostic (4.51e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (8.80e-2)" "unprognostic (1.06e-1)" "unprognostic (2.83e-1)" "unprognostic (6.40e-2)" "unprognostic (8.21e-2)" TSSK6 "CT72, FLJ24002, SSTK" ENSG00000178093 "Testis specific serine kinase 6" Q9BXA6 19 19512418-19515548 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 135 "testis: 206.2" "Cell type enriched" "Detected in many" 11 "Late spermatids: 18236.6" "Cell type enriched" "Detected in many" 715 "Spermatogenic cell types: 18236.6" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA065281 Uncertain "Nuclear bodies" NA NA "Cluster 79: Testis - Spermatogenesis" "Cluster 6: Non-specific - Immune response" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 25 "Nuclear bodies" "HPA065281: " "unprognostic (2.76e-2)" "unprognostic (3.52e-2)" "unprognostic (1.20e-1)" "unprognostic (1.15e-1)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" TTC21B "FAP60, FLA17, FLJ11457, IFT139, IFT139B, JBTS11, NPHP12, THM1" ENSG00000123607 "Tetratricopeptide repeat domain 21B" Q7Z4L5 2 165857475-165953851 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Intellectual disability, Joubert syndrome, Meckel syndrome, Nephronophthisis, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 310.4;Fallopian tube ciliated cells: 256.7;Respiratory ciliated cells: 291.7" "Cell type enhanced" "Detected in all" "Ciliated cells: 310.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 22697909.0" "Tissue enhanced" "Detected in some" "fallopian tube: 5128927.5" HPA073293 Supported Approved "Primary cilium,Centriolar satellite,Basal body,Cytosol,Connecting piece,Mid piece,Principal piece,End piece" NA No "Cluster 14: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 2: Neurons - Nucleosome" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 107: Ciliated cells - Cilia assembly & function" 16 "Primary cilium, Centriolar satellite, Basal body" "Cytosol, Connecting piece, Mid piece, Principal piece, End piece" "HPA073293: " "unprognostic (1.35e-1)" "unprognostic (2.03e-3)" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" "unprognostic (1.13e-1)" "unprognostic (5.25e-2)" "unprognostic (3.23e-1)" "unprognostic (4.52e-2)" "validated prognostic favorable (5.35e-6)" "validated prognostic favorable (2.28e-4)" "unprognostic (6.59e-2)" "unprognostic (2.77e-3)" "unprognostic (1.28e-1)" "unprognostic (9.44e-2)" "unprognostic (1.68e-1)" "unprognostic (3.38e-1)" "unprognostic (1.17e-1)" "unprognostic (2.11e-2)" "unprognostic (3.36e-1)" "unprognostic (2.86e-1)" "unprognostic (3.90e-3)" "unprognostic (3.68e-1)" "unprognostic (2.25e-1)" "unprognostic (2.45e-3)" "unprognostic (2.61e-1)" "unprognostic (6.86e-2)" "unprognostic (1.43e-1)" "unprognostic (3.10e-2)" "unprognostic (4.20e-2)" TTC23 "FLJ12572, HCC-8" ENSG00000103852 "Tetratricopeptide repeat domain 23" Q5W5X9 15 99136323-99251223 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 230.0" "Cell type enhanced" "Detected in many" "Myocytes: 230.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.8" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039806, HPA040369" Uncertain Approved "Primary cilium transition zone,Cytosol" NA NA "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 18 Cytosol "Primary cilium transition zone" "HPA039806: , HPA040369: " "unprognostic (8.89e-2)" "unprognostic (5.78e-2)" "unprognostic (2.74e-2)" "unprognostic (1.00e-1)" "unprognostic (3.67e-1)" "unprognostic (3.66e-1)" "unprognostic (6.12e-2)" "unprognostic (4.75e-2)" "unprognostic (1.36e-1)" "unprognostic (1.29e-2)" "potential prognostic favorable (1.83e-4)" "unprognostic (1.84e-2)" "unprognostic (1.72e-1)" "unprognostic (5.83e-2)" "unprognostic (3.78e-1)" "unprognostic (1.47e-1)" "unprognostic (1.77e-2)" "unprognostic (7.11e-2)" "unprognostic (1.61e-1)" "unprognostic (7.36e-2)" "unprognostic (1.76e-1)" "unprognostic (1.47e-2)" "unprognostic (8.12e-3)" "unprognostic (1.08e-1)" "unprognostic (3.24e-2)" "unprognostic (2.59e-2)" "unprognostic (1.35e-1)" "unprognostic (1.40e-2)" "unprognostic (2.68e-1)" "unprognostic (9.46e-2)" "unprognostic (3.25e-1)" TTC26 "dyf-13, DYF13, FLJ12571, IFT56" ENSG00000105948 "Tetratricopeptide repeat domain 26" A0AVF1 7 139133744-139191986 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 106.4;Early primary spermatocytes: 85.2;Endometrial ciliated cells: 128.5;Ependymal cells: 202.7;Epididymal efferent duct ciliated cells: 113.3;Fallopian tube ciliated cells: 161.0;Late primary spermatocytes: 105.4;Respiratory ciliated cells: 254.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 254.7;Spermatogenic cell types: 105.4" "Cell type enhanced" "Detected in all" "ependymal cell: 215.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Lung - Respiratory ciliated cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 17202466.1" "Tissue enriched" "Detected in some" "fallopian tube: 5279646.2" "HPA036338, HPA061867" Enhanced Approved "Nucleoplasm,Primary cilium,Mitochondria,Cytosol" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 39: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 51 Nucleoplasm "Primary cilium, Mitochondria, Cytosol" "HPA036338: , HPA061867: " "unprognostic (3.41e-1)" "unprognostic (3.37e-1)" "unprognostic (7.46e-3)" "unprognostic (5.11e-2)" "unprognostic (2.42e-1)" "unprognostic (7.01e-2)" "unprognostic (1.10e-2)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (2.12e-1)" "unprognostic (5.65e-3)" "potential prognostic favorable (6.42e-4)" "unprognostic (1.07e-1)" "unprognostic (2.22e-1)" "unprognostic (5.03e-3)" "unprognostic (8.54e-2)" "unprognostic (2.51e-2)" "unprognostic (3.42e-2)" "unprognostic (3.29e-1)" "unprognostic (2.61e-1)" "unprognostic (2.18e-2)" "unprognostic (9.47e-2)" "unprognostic (2.42e-1)" "unprognostic (2.20e-1)" "unprognostic (1.41e-2)" "unprognostic (1.46e-1)" "unprognostic (2.79e-2)" "unprognostic (7.31e-2)" "unprognostic (2.58e-1)" "unprognostic (4.46e-2)" "unprognostic (1.04e-1)" TTC27 FLJ20272 ENSG00000018699 "Tetratricopeptide repeat domain 27" Q6P3X3 2 32628032-32821051 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Megakaryocyte progenitors: 309.0" "Cell type enhanced" "Detected in many" "Megakaryocytes: 309.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 3240807.6" HPA031246 Approved Approved Nucleoli,Mitochondria No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 57: Testis - Spermatogenesis" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 31 Mitochondria Nucleoli "HPA031246: " "unprognostic (1.29e-1)" "unprognostic (1.29e-2)" "unprognostic (2.94e-1)" "unprognostic (4.58e-2)" "unprognostic (6.40e-2)" "unprognostic (1.34e-1)" "unprognostic (1.93e-1)" "unprognostic (2.70e-1)" "unprognostic (2.21e-1)" "unprognostic (1.53e-2)" "potential prognostic favorable (1.71e-6)" "unprognostic (2.71e-2)" "unprognostic (3.97e-2)" "validated prognostic unfavorable (1.14e-5)" "validated prognostic unfavorable (7.01e-4)" "unprognostic (2.25e-2)" "unprognostic (3.62e-3)" "unprognostic (2.29e-1)" "unprognostic (1.48e-1)" "unprognostic (3.85e-3)" "unprognostic (2.16e-2)" "validated prognostic unfavorable (3.24e-4)" "validated prognostic unfavorable (8.93e-5)" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (7.17e-3)" "unprognostic (6.26e-2)" "unprognostic (1.06e-1)" "unprognostic (3.20e-1)" "unprognostic (1.68e-2)" "unprognostic (1.37e-1)" TTC28 KIAA1043 ENSG00000100154 "Tetratricopeptide repeat domain 28" Q96AY4 22 27978014-28679840 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibro-adipogenic progenitors: 907.5;Proximal tubule cells: 897.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 5627260.2;Smooth muscle cells: 3196410.9" "Group enriched" "Detected in many" "blood vessel: 1979704.8;intestine: 687706.9" HPA001080 Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 51: Neurons - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 "Microtubules, Cytokinetic bridge, Mitotic spindle" Cytosol "HPA001080: " "potential prognostic favorable (9.62e-4)" "unprognostic (3.06e-1)" "unprognostic (3.48e-3)" "unprognostic (1.49e-2)" "unprognostic (3.84e-2)" "unprognostic (1.22e-1)" "unprognostic (4.18e-2)" "unprognostic (9.70e-2)" "unprognostic (4.56e-2)" "unprognostic (9.27e-3)" "validated prognostic favorable (9.65e-10)" "validated prognostic favorable (1.22e-4)" "unprognostic (5.56e-2)" "unprognostic (2.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.39e-2)" "unprognostic (1.52e-1)" "unprognostic (1.10e-2)" "unprognostic (3.74e-3)" "unprognostic (1.30e-1)" "unprognostic (1.70e-1)" "unprognostic (8.14e-2)" "unprognostic (9.96e-2)" "unprognostic (1.90e-1)" "unprognostic (1.66e-1)" "unprognostic (8.54e-2)" "unprognostic (2.83e-2)" "unprognostic (1.80e-2)" "unprognostic (1.02e-1)" "unprognostic (4.46e-3)" "unprognostic (3.53e-2)" TTC3 "DCRR1, RNF105, TPRD, TPRDI, TPRDII, TPRDIII" ENSG00000182670 "Tetratricopeptide repeat domain 3" P53804 21 37073226-37203112 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Gonadotrophs: 1171.9;Lactotrophs: 1476.3;Somatotrophs: 1773.0" "Cell type enhanced" "Detected in all" "Pituitary endocrine cells: 1773.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Fallopian tube cells: 152442.0;Neurons: 140159.7" "Tissue enriched" "Detected in single" 1387 "salivary gland: 138702.8" "HPA016810, HPA023964, HPA036304" Uncertain Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 30: Non-specific - DNA binding" "Cluster 22: Epididymis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" 11 "Nucleoplasm, Nucleoli" Cytosol "HPA016810: , HPA023964: , HPA036304: " "unprognostic (1.03e-1)" "unprognostic (2.54e-2)" "unprognostic (1.02e-1)" "unprognostic (1.28e-1)" "unprognostic (1.46e-1)" "unprognostic (1.05e-1)" "unprognostic (2.33e-1)" "unprognostic (3.79e-3)" "unprognostic (3.94e-2)" "unprognostic (2.93e-1)" "potential prognostic favorable (2.32e-4)" "unprognostic (3.50e-2)" "unprognostic (2.95e-1)" "unprognostic (1.38e-1)" "unprognostic (2.62e-1)" "unprognostic (2.23e-2)" "unprognostic (3.34e-1)" "unprognostic (8.21e-3)" "unprognostic (2.47e-1)" "unprognostic (5.12e-2)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (9.68e-2)" "unprognostic (2.08e-1)" "unprognostic (5.64e-2)" "unprognostic (3.14e-1)" "unprognostic (2.07e-1)" "unprognostic (2.10e-2)" "unprognostic (2.18e-1)" "unprognostic (2.30e-2)" "unprognostic (4.20e-2)" TTC30A "FAP259, FLJ13946, IFT70A" ENSG00000197557 "Tetratricopeptide repeat domain 30A" Q86WT1 2 177612999-177618742 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 34.6;Fallopian tube ciliated cells: 20.6;Late primary spermatocytes: 122.7;Respiratory ciliated cells: 31.9" "Group enriched" "Detected in many" 7 "Ciliated cells: 31.9;Spermatogenic cell types: 122.7" "Cell type enhanced" "Detected in many" "ependymal cell: 17.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 10604957.1;Fallopian tube cells: 14394123.8" "Tissue enriched" "Detected in single" 29961 "fallopian tube: 2996123.1" "HPA051714, HPA052100, HPA052487" Supported Approved "Nucleoplasm,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 59 "Primary cilium, Centrosome, Basal body" "Nucleoplasm, Primary cilium tip" "HPA051714: , HPA052100: , HPA052487: " "unprognostic (4.60e-1)" "unprognostic (1.09e-1)" "unprognostic (4.22e-2)" "unprognostic (7.38e-2)" "unprognostic (1.40e-1)" "unprognostic (2.25e-2)" "unprognostic (1.27e-2)" "unprognostic (1.07e-2)" "unprognostic (3.81e-2)" "unprognostic (5.83e-3)" "potential prognostic favorable (2.24e-5)" "unprognostic (9.25e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-2)" "unprognostic (3.93e-2)" "unprognostic (1.74e-1)" "unprognostic (9.82e-2)" "unprognostic (1.46e-1)" "unprognostic (1.17e-2)" "unprognostic (1.67e-1)" "unprognostic (2.23e-1)" "unprognostic (1.69e-1)" "unprognostic (1.29e-1)" "unprognostic (5.40e-2)" "unprognostic (5.24e-2)" "unprognostic (1.62e-2)" "unprognostic (8.90e-2)" "unprognostic (5.90e-3)" "unprognostic (1.47e-1)" "potential prognostic unfavorable (5.92e-4)" "unprognostic (1.04e-1)" TTC30B "fleer, FLJ30990, IFT70B" ENSG00000196659 "Tetratricopeptide repeat domain 30B" Q8N4P2 2 177548998-177552796 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 17.4;Early primary spermatocytes: 15.3;Endometrial ciliated cells: 16.6;Ependymal cells: 18.0;Fallopian tube ciliated cells: 33.7;Late primary spermatocytes: 30.3;Respiratory ciliated cells: 54.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 54.0;Spermatogenic cell types: 30.3" "Cell type enriched" "Detected in many" 5 "ependymal cell: 25.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Group enriched" "Detected in some" "Fallopian tube cells: 4953172.6;Oocytes: 2067349.6" "Tissue enriched" "Detected in single" 3688 "fallopian tube: 368805.9" "HPA051714, HPA052100, HPA052487" Supported Approved "Nucleoplasm,Primary cilium,Primary cilium tip,Centrosome,Basal body" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 22: Epididymis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 84 "Primary cilium, Centrosome, Basal body" "Nucleoplasm, Primary cilium tip" "HPA051714: , HPA052100: , HPA052487: " "unprognostic (4.81e-2)" "unprognostic (1.29e-1)" "unprognostic (1.15e-1)" "unprognostic (2.47e-1)" "unprognostic (1.66e-1)" "unprognostic (1.03e-1)" "unprognostic (3.60e-2)" "unprognostic (3.90e-3)" "unprognostic (2.59e-1)" "unprognostic (1.15e-2)" "potential prognostic favorable (5.42e-5)" "unprognostic (1.71e-2)" "unprognostic (2.13e-1)" "unprognostic (8.15e-3)" "unprognostic (1.87e-2)" "unprognostic (2.57e-1)" "unprognostic (9.79e-2)" "unprognostic (1.32e-1)" "unprognostic (1.05e-3)" "unprognostic (3.50e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (3.24e-1)" "unprognostic (1.01e-1)" "unprognostic (7.14e-3)" "unprognostic (1.54e-1)" "unprognostic (1.15e-1)" "unprognostic (2.02e-1)" "unprognostic (2.00e-1)" "unprognostic (1.80e-2)" "unprognostic (5.95e-2)" TTC6 "C14orf25, NCRNA00291" ENSG00000139865 "Tetratricopeptide repeat domain 6" Q86TZ1 14 37595629-38041442 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 4.0;prostate: 6.1;testis: 4.6" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 407.8;Ependymal cells: 949.0;Mucous neck cells: 212.1;Prostatic club cells: 237.3;Prostatic glandular cells: 1854.6;Respiratory basal cells: 226.2" "Cell type enhanced" "Detected in many" "Ciliated cells: 949.0;Glandular cells: 1854.6;Luminal cells: 407.8" "Cell type enriched" "Detected in many" 6 "ependymal cell: 1114.0" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 10.3;Prostate Adenocarcinoma (TCGA): 20.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 4 "prostate cancer: 11.3" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Skin - Eccrine sweat gland cells, Testis - Early spermatids" "Not detected" "Not detected" "Region enriched" "Detected in some" 6 "midbrain: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA069293 Approved "Centrosome,Basal body" NA NA "Cluster 21: Testis - Mixed function" "Cluster 46: Brainstem - Mixed function" "Cluster 60: Prostate cancer - Unknown function" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" Centrosome "Basal body" "HPA069293: " "unprognostic (1.58e-3)" "unprognostic (4.74e-2)" "unprognostic (1.92e-2)" "unprognostic (5.86e-2)" "unprognostic (1.88e-1)" "unprognostic (3.33e-3)" "unprognostic (2.62e-1)" "unprognostic (4.82e-2)" "unprognostic (2.80e-1)" "unprognostic (1.39e-1)" "unprognostic (7.32e-2)" "unprognostic (1.35e-1)" "unprognostic (9.08e-2)" TTC8 "BBS8, RP51" ENSG00000165533 "Tetratricopeptide repeat domain 8" Q8TAM2 14 88824153-88881078 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Intellectual disability, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 191.5;Cone photoreceptor cells: 316.7;Ependymal cells: 269.6;Gonadotrophs: 200.5;Lactotrophs: 298.1;Rod photoreceptor cells: 322.4;Sertoli cells: 339.2;Somatotrophs: 200.7;Thyrotrophs: 259.5" "Cell type enhanced" "Detected in all" "Ciliated cells: 269.6;Neuronal cells: 322.4;Pituitary endocrine cells: 298.1;Reproductive supporting cells: 339.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Lineage enriched" "Detected in many" 6 "granulocytes: 13.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Fibroblasts, Testis - Sertoli cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 583075.5;Pancreatic islets: 466191.3" "Tissue enriched" "Detected in some" "fallopian tube: 3442317.7" HPA003310 Approved "Nucleoli fibrillar center,Basal body,Perinuclear theca,Flagellar centriole" NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 79: Photoreceptor cells - Phototransduction" 16 "Nucleoli fibrillar center, Basal body" "Perinuclear theca, Flagellar centriole" "HPA003310: " "unprognostic (8.34e-2)" "unprognostic (5.43e-2)" "unprognostic (6.09e-2)" "unprognostic (3.79e-2)" "unprognostic (2.59e-2)" "unprognostic (1.81e-1)" "unprognostic (2.34e-1)" "unprognostic (3.10e-1)" "unprognostic (1.92e-1)" "unprognostic (6.76e-2)" "potential prognostic favorable (2.19e-4)" "unprognostic (5.52e-3)" "unprognostic (1.02e-2)" "unprognostic (3.78e-3)" "unprognostic (1.65e-2)" "unprognostic (1.55e-3)" "unprognostic (1.79e-1)" "unprognostic (3.51e-1)" "unprognostic (3.23e-3)" "unprognostic (9.90e-3)" "unprognostic (2.15e-1)" "unprognostic (8.27e-2)" "unprognostic (8.02e-2)" "unprognostic (1.71e-1)" "unprognostic (2.06e-1)" "unprognostic (9.26e-3)" "unprognostic (1.48e-1)" "unprognostic (5.71e-2)" "unprognostic (2.92e-1)" "unprognostic (2.16e-1)" "unprognostic (7.52e-2)" TTL MGC46235 ENSG00000114999 "Tubulin tyrosine ligase" Q8NG68 2 112482156-112541739 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 108.2" "Cell type enhanced" "Detected in many" "Glial cells: 108.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 907000.4;Neurons: 314915.6" "Group enriched" "Detected in some" 15311 "cerebral cortex: 1410036.4;lymphoid tissue: 1652122.8" HPA066819 Approved Nucleoplasm,Vesicles NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 34: Non-specific - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 3 Vesicles Nucleoplasm "HPA066819: " "unprognostic (2.81e-1)" "unprognostic (2.02e-1)" "unprognostic (8.62e-3)" "unprognostic (1.19e-1)" "unprognostic (2.39e-1)" "unprognostic (7.21e-2)" "unprognostic (5.36e-1)" "unprognostic (3.12e-2)" "unprognostic (2.26e-1)" "unprognostic (1.57e-1)" "unprognostic (4.39e-2)" "unprognostic (5.49e-2)" "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.94e-1)" "unprognostic (2.00e-1)" "unprognostic (1.01e-2)" "unprognostic (1.56e-3)" "unprognostic (2.87e-1)" "unprognostic (3.13e-1)" "unprognostic (2.58e-1)" "unprognostic (1.91e-1)" TTLL10 "FLJ36119, TTLL5" ENSG00000162571 "Tubulin tyrosine ligase like 10" Q6ZVT0 1 1173880-1197936 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "fallopian tube: 10.1;testis: 39.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1302.6" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 1302.6" "Group enriched" "Detected in some" 13 "choroid plexus epithelial cell: 23.9;ependymal cell: 41.7" "Cancer enhanced" "Detected in some" "Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma (TCGA): 2.7;Uterine Corpus Endometrial Carcinoma (TCGA): 2.4" "Region enhanced" "Detected in many" "choroid plexus: 28.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Endothelial cells, Breast - Endothelial cells, Lung - Respiratory ciliated cells, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA042712 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 10 Cytosol "Plasma membrane" "HPA042712: " "unprognostic (4.96e-2)" "unprognostic (8.83e-3)" "unprognostic (6.94e-3)" "potential prognostic favorable (7.02e-5)" "unprognostic (2.06e-1)" "unprognostic (3.69e-2)" "unprognostic (1.93e-1)" "unprognostic (2.13e-1)" "unprognostic (4.00e-2)" TTLL13 "FLJ46079, MGC33417, TTLL13P" ENSG00000213471 "Tubulin tyrosine ligase like 13" A6NNM8 15 90249530-90265482 "Predicted intracellular proteins" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 47 "testis: 7.6" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Late spermatids: 5.2" "Cell type enriched" "Detected in single" 7 "Spermatogenic cell types: 5.2" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA040133, HPA041305" Enhanced Approved "Plasma membrane,Basal body,Cytosol" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 56: Late spermatids - Spermiogenesis: Maturation" "Plasma membrane, Cytosol" "Basal body" "HPA040133: , HPA041305: " TTLL5 "KIAA0998, STAMP" ENSG00000119685 "Tubulin tyrosine ligase like 5" Q6EMB2 14 75633625-75955079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Ligase "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.7" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 388.0;Cone photoreceptor cells: 511.3;Endometrial ciliated cells: 426.8;Ependymal cells: 491.2;Respiratory ciliated cells: 352.9;Rod photoreceptor cells: 477.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 491.2;Neuronal cells: 511.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA032128 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 47: Testis - Mixed function" "Cluster 30: White matter - Myelination" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 79: Photoreceptor cells - Phototransduction" 4 "Plasma membrane, Cytosol" "HPA032128: " "unprognostic (1.38e-2)" "unprognostic (3.43e-1)" "unprognostic (3.66e-1)" "unprognostic (6.76e-3)" "unprognostic (2.94e-1)" "unprognostic (1.69e-1)" "unprognostic (3.20e-2)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "unprognostic (3.31e-3)" "unprognostic (1.12e-3)" "unprognostic (1.21e-2)" "unprognostic (6.22e-2)" "potential prognostic unfavorable (1.04e-4)" "unprognostic (1.80e-1)" "unprognostic (1.29e-1)" "unprognostic (6.14e-3)" "unprognostic (6.64e-2)" "unprognostic (3.50e-1)" "unprognostic (3.81e-1)" "unprognostic (1.38e-2)" "unprognostic (3.85e-3)" "unprognostic (1.90e-2)" "unprognostic (1.12e-2)" "unprognostic (8.48e-2)" "unprognostic (2.70e-1)" "unprognostic (5.64e-3)" "unprognostic (2.34e-1)" "unprognostic (2.20e-1)" "unprognostic (7.92e-2)" "unprognostic (1.98e-1)" TTLL9 "C20orf125, dJ310O13.1" ENSG00000131044 "Tubulin tyrosine ligase like 9" Q3SXZ7 20 31870634-31945000 "Cancer-related genes, Predicted intracellular proteins" Ligase "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "choroid plexus: 14.6" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 315.6;Endometrial ciliated cells: 87.1;Ependymal cells: 319.0;Epididymal efferent duct ciliated cells: 55.0;Fallopian tube ciliated cells: 105.5;Late primary spermatocytes: 74.5;Late spermatids: 146.6;Respiratory ciliated cells: 211.4" "Group enriched" "Detected in many" 5 "Ciliated cells: 319.0;Spermatogenic cell types: 146.6" "Group enriched" "Detected in many" 5 "choroid plexus epithelial cell: 246.0;ependymal cell: 347.9" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.8;Uterine Corpus Endometrial Carcinoma (TCGA): 1.4" "Region enhanced" "Detected in all" "choroid plexus: 22.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Breast - Breast glandular cells, Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041772, HPA055676" Uncertain Approved "Nucleoplasm,Microtubules,Mitotic spindle,Primary cilium,Basal body,Mid piece,Principal piece,End piece" Yes NA "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 3: Choroid plexus - Cilium" "Cluster 11: Neuronal - Sensory perception" "Cluster 34: Ciliated cells - Cilia assembly & function" "Microtubules, Mid piece, Principal piece, End piece" "Nucleoplasm, Mitotic spindle, Primary cilium, Basal body" "HPA041772: , HPA055676: " "unprognostic (5.44e-1)" "unprognostic (2.30e-1)" "unprognostic (1.72e-1)" "unprognostic (1.82e-3)" "unprognostic (1.86e-1)" TUBA1A "B-ALPHA-1, FLJ25113, TUBA3" ENSG00000167552 "Tubulin alpha 1a" Q71U36 12 49184686-49189080 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" Hydrolase "Cancer-related genes, Disease variant, FDA approved drug targets, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 2689.9" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 657.9;Decidual stromal cells: 1712.1;Fallopian tube ciliated cells: 1193.1;Hofbauer cells: 683.1;Mast cells: 745.4;Müller glia: 713.0;Neutrophils: 742.8;Respiratory ciliated cells: 1523.0;Schwann cells: 843.6;Smooth muscle cells: 701.4" "Cell type enhanced" "Detected in many" "Ciliated cells: 1523.0;Stromal cells: 1712.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 786.8" "Cancer enriched" "Detected in all" 10 "Glioblastoma Multiforme (TCGA): 3672.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1667.7" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Neuroblastoma: 1234.9" "Adipose subcutaneous - Adipose progenitor cells, Colon - Smooth muscle cells, Kidney - Macrophages, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 21611 "Microglia and Neuropil: 2161078.4" "Not detected" "Not detected" "CAB008686, HPA039247, HPA043684, HPA063394" Enhanced Enhanced "Microtubules,Primary cilium" NA NA "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 232 Microtubules "Primary cilium" "CAB008686: , HPA039247: , HPA043684: , HPA063394: " "unprognostic (1.72e-1)" "unprognostic (2.85e-2)" "unprognostic (1.92e-1)" "unprognostic (8.03e-2)" "unprognostic (1.20e-1)" "unprognostic (1.90e-3)" "unprognostic (1.29e-1)" "unprognostic (4.65e-1)" "unprognostic (1.78e-2)" "unprognostic (1.19e-2)" "unprognostic (1.90e-2)" "unprognostic (2.96e-3)" "unprognostic (2.06e-1)" "unprognostic (2.48e-2)" "unprognostic (9.56e-2)" "unprognostic (4.82e-2)" "unprognostic (5.32e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" "unprognostic (1.98e-1)" "unprognostic (2.23e-1)" "unprognostic (1.63e-3)" "unprognostic (2.07e-1)" "unprognostic (1.38e-1)" "unprognostic (2.03e-1)" "unprognostic (1.58e-2)" "unprognostic (1.14e-2)" "unprognostic (4.00e-3)" "unprognostic (1.65e-1)" "unprognostic (3.71e-2)" "unprognostic (1.50e-1)" TUBA1B K-ALPHA-1 ENSG00000123416 "Tubulin alpha 1b" P68363 12 49127782-49131397 "Essential proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythrocyte progenitors: 1492.1;Esophageal basal cells: 1765.6;Extravillous trophoblasts: 3078.9;Hofbauer cells: 3042.0;Megakaryocytes: 2862.1;Migrating cytotrophoblasts: 1655.8" "Cell type enhanced" "Detected in all" "Megakaryocytes: 2862.1;Mononuclear phagocytes: 3042.0;Trophoblast cells: 3078.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4053513 "Fallopian tube cells: 267281057.4;Granulosa cells: 259884609.3;Neurons: 688888220.3" "Not detected" "Not detected" "CAB011513, HPA039247, HPA043684, HPA063394" Enhanced Enhanced "Microtubules,Primary cilium" NA Yes "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 38: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 134 Microtubules "Primary cilium" "CAB011513: , HPA039247: , HPA043684: , HPA063394: " "unprognostic (1.63e-3)" "potential prognostic unfavorable (7.53e-5)" "unprognostic (1.81e-2)" "unprognostic (5.38e-3)" "unprognostic (3.43e-2)" "unprognostic (3.44e-1)" "unprognostic (2.30e-1)" "unprognostic (1.32e-1)" "unprognostic (6.19e-3)" "unprognostic (2.67e-3)" "validated prognostic unfavorable (1.22e-6)" "validated prognostic unfavorable (6.78e-6)" "unprognostic (8.72e-3)" "validated prognostic unfavorable (1.97e-9)" "validated prognostic unfavorable (4.90e-5)" "validated prognostic unfavorable (6.52e-6)" "validated prognostic unfavorable (3.96e-5)" "potential prognostic favorable (8.01e-4)" "unprognostic (3.52e-1)" "unprognostic (3.21e-1)" "unprognostic (1.55e-1)" "unprognostic (1.30e-3)" "unprognostic (7.34e-2)" "unprognostic (1.48e-2)" "unprognostic (1.48e-1)" "unprognostic (9.77e-2)" "unprognostic (9.50e-2)" "unprognostic (2.66e-1)" "unprognostic (2.84e-1)" "unprognostic (1.54e-1)" "unprognostic (8.27e-2)" TUBA1C "bcm948, MGC10851, MGC14580, TUBA6" ENSG00000167553 "Tubulin alpha 1c" Q9BQE3 12 49188736-49274600 "Essential proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 435.6" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 1230.3;Esophageal basal cells: 703.3;Esophageal suprabasal cells: 1115.9;Extravillous trophoblasts: 1578.0;Megakaryocytes: 1285.8;Oocytes: 810.5;Suprabasal keratinocytes: 621.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1230.3;Megakaryocytes: 1285.8;Suprabasal cells: 1115.9;Trophoblast cells: 1578.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 99.3" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 127259 "cerebral cortex: 12725928.5" "HPA039247, HPA043684, HPA063394" Supported Enhanced "Microtubules,Primary cilium" NA Yes 220000000 "Cluster 41: Basophils - Unknown function" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 72: Neuronal - Signal transduction" "Cluster 65: Non-specific - Cell growth & division" 97 Microtubules "Primary cilium" "HPA039247: , HPA043684: , HPA063394: " "potential prognostic unfavorable (1.76e-4)" "unprognostic (1.21e-2)" "unprognostic (3.65e-2)" "unprognostic (3.57e-2)" "potential prognostic favorable (9.95e-4)" "unprognostic (2.30e-1)" "unprognostic (2.66e-3)" "potential prognostic unfavorable (1.99e-4)" "unprognostic (2.61e-2)" "unprognostic (2.48e-2)" "validated prognostic unfavorable (3.62e-5)" "validated prognostic unfavorable (9.20e-6)" "unprognostic (6.06e-3)" "validated prognostic unfavorable (3.77e-10)" "validated prognostic unfavorable (3.45e-6)" "validated prognostic unfavorable (2.94e-4)" "validated prognostic unfavorable (1.28e-5)" "unprognostic (1.19e-1)" "unprognostic (2.44e-1)" "unprognostic (4.03e-2)" "unprognostic (1.06e-1)" "potential prognostic unfavorable (5.29e-6)" "unprognostic (5.97e-2)" "unprognostic (1.44e-1)" "unprognostic (1.34e-1)" "unprognostic (2.23e-2)" "unprognostic (2.99e-1)" "unprognostic (2.01e-1)" "unprognostic (1.59e-1)" "unprognostic (3.25e-1)" "unprognostic (3.79e-2)" TUBA3C "bA408E5.3, TUBA2" ENSG00000198033 "Tubulin alpha 3c" P0DPH7 13 19173772-19181824 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 711 "testis: 390.0" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 274.5;Early primary spermatocytes: 526.7;Early spermatids: 627.4;Late primary spermatocytes: 1926.6;Late spermatids: 279.9" "Cell type enriched" "Detected in some" 147 "Spermatogenic cell types: 1926.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Liver Hepatocellular Carcinoma (TCGA): 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Bone cancer: 25.0;lymphoma: 21.8;Myeloma: 25.3" "Stomach - Parietal cells, Testis - Early spermatids" "Low region specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039247, HPA043684, HPA063394" Uncertain Enhanced "Microtubules,Primary cilium" NA Yes "Cluster 23: Testis - Spermatogenesis" "Cluster 21: Lymphoma - Adaptive immune response" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 7 Microtubules "Primary cilium" "HPA039247: , HPA043684: , HPA063394: " "unprognostic (7.61e-1)" "potential prognostic unfavorable (4.79e-5)" "unprognostic (5.72e-2)" "unprognostic (3.83e-1)" "unprognostic (9.08e-2)" "unprognostic (5.12e-2)" "unprognostic (1.95e-1)" TUBA3D H2-ALPHA ENSG00000075886 "Tubulin alpha 3d" P0DPH8 2 131476119-131482934 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 16 "heart muscle: 82.4;testis: 211.7" "Group enriched" "Detected in some" 4 "Differentiating spermatogonia: 258.2;Early primary spermatocytes: 593.4;Early spermatids: 299.1;Late primary spermatocytes: 922.3" "Cell type enriched" "Detected in many" 18 "Spermatogenic cell types: 922.3" "Low cell type specificity" "Detected in single" "Cancer enhanced" "Detected in many" "Kidney Renal Clear Cell Carcinoma (TCGA): 15.3;Testicular Germ Cell Tumor (TCGA): 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Prostate - Prostate glandular cells, Testis - Early spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004972, HPA039247, HPA043684, HPA063394" Uncertain Enhanced "Microtubules,Primary cilium" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 60: Prostate cancer - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" Microtubules "Primary cilium" "CAB004972: , HPA039247: , HPA043684: , HPA063394: " "unprognostic (4.57e-3)" "unprognostic (1.38e-2)" "unprognostic (4.05e-2)" "unprognostic (5.83e-2)" "unprognostic (7.07e-2)" "unprognostic (9.94e-3)" "unprognostic (3.25e-1)" "unprognostic (2.29e-1)" "unprognostic (7.16e-2)" "unprognostic (4.35e-1)" "unprognostic (2.30e-1)" TUBA3E ENSG00000152086 "Tubulin alpha 3e" Q6PEY2 2 130191745-130198439 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "heart muscle: 51.2;testis: 169.2" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 147.8;Early primary spermatocytes: 302.8;Early spermatids: 205.2;Late primary spermatocytes: 822.2;Late spermatids: 116.8" "Cell type enriched" "Detected in some" 22 "Spermatogenic cell types: 822.2" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "thyroid cancer: 1.0" "Cell type enriched" "Detected in single" 13243 "Neurons: 1324297.0" "Tissue enriched" "Detected in single" 7523 "lymphoid tissue: 752337.9" "HPA039247, HPA043684, HPA063394" Uncertain Enhanced "Microtubules,Primary cilium" NA NA "Cluster 35: Non-specific - Mixed function" "Cluster 2: Neurons - Nucleosome" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 3 Microtubules "Primary cilium" "HPA039247: , HPA043684: , HPA063394: " "potential prognostic unfavorable (6.21e-4)" "unprognostic (9.07e-3)" "unprognostic (3.55e-2)" "unprognostic (6.56e-3)" "unprognostic (2.42e-1)" "unprognostic (2.10e-1)" TUBA4A "FLJ30169, H2-ALPHA, TUBA1" ENSG00000127824 "Tubulin alpha 4a" P68366 2 219249710-219277902 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Amyotrophic lateral sclerosis, FDA approved drug targets, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 345.9;tongue: 249.0" "Cell type enhanced" "Detected in many" "Early spermatids: 574.0;Esophageal apical cells: 418.3;Esophageal suprabasal cells: 573.1;Late spermatids: 1173.7;Megakaryocytes: 982.9;Neutrophils: 407.1;Platelets: 3539.4;Suprabasal keratinocytes: 466.0" "Cell type enhanced" "Detected in many" "Megakaryocytes: 982.9;Platelets: 3539.4;Spermatogenic cell types: 1173.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Kidney - Macrophages, Spleen - Neutrophils_2, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 2744238068.9;Microglia and Neuropil: 2920641541.4;Neurons: 2335094440.9" "Tissue enriched" "Detected in all" "cerebral cortex: 5567028366.6" "CAB004621, CAB005887, HPA039247, HPA043684, HPA063394" Approved Enhanced "Microtubules,Primary cilium" NA NA 210000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 7: Liver cancer - Metabolism" "Cluster 47: Platelets - Hemostasis" 92 Microtubules "Primary cilium" "CAB004621: , CAB005887: , HPA039247: , HPA043684: , HPA063394: " "unprognostic (4.77e-2)" "unprognostic (7.92e-3)" "unprognostic (2.82e-1)" "unprognostic (2.31e-1)" "unprognostic (1.92e-1)" "unprognostic (2.70e-1)" "unprognostic (9.98e-3)" "unprognostic (2.11e-2)" "unprognostic (5.56e-2)" "unprognostic (2.28e-2)" "unprognostic (1.12e-1)" "unprognostic (5.07e-2)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (3.27e-7)" "unprognostic (7.47e-2)" "potential prognostic unfavorable (1.22e-4)" "unprognostic (1.12e-2)" "unprognostic (2.43e-2)" "unprognostic (7.50e-2)" "unprognostic (2.22e-2)" "unprognostic (4.32e-2)" "unprognostic (5.33e-2)" "unprognostic (5.69e-2)" "unprognostic (2.26e-2)" "unprognostic (2.55e-1)" "unprognostic (9.89e-2)" "unprognostic (1.93e-1)" "unprognostic (3.40e-1)" "unprognostic (2.56e-1)" "unprognostic (6.02e-3)" "unprognostic (1.33e-1)" TUBB "M40, MGC16435, OK/SW-cl.56, Tubb5" ENSG00000196230 "Tubulin beta class I" P07437 6 30717435-30725538 "Disease related genes, Essential proteins, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 30.8;Brain excitatory neurons: 61.7;Brain inhibitory neurons: 51.5;Loop of henle epithelial cells: 27.7;Megakaryocytes: 24.7;Microglia: 43.4;Oligodendrocyte progenitor cells: 34.2;Oligodendrocytes: 31.4;Other brain neurons: 170.6;Papillary tip epithelial cells: 33.2;Podocytes: 25.0;Renal collecting duct principal cells: 43.4" "Cell type enhanced" "Detected in many" "Ductal cells: 43.4;Glial cells: 43.4;Neuronal cells: 170.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Prostate - Smooth muscle cells, Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 5013329481.2" "Low tissue specificity" "Detected in all" "CAB005417, CAB012406, HPA043640, HPA046280" Enhanced Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes Yes 160000000 "Cluster 33: Non-specific - ATP binding" "Cluster 54: Non-specific - Ribosome" "Cluster 44: Non-specific - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 211 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB005417: , CAB012406: , HPA043640: , HPA046280: " "unprognostic (1.16e-1)" "unprognostic (2.69e-2)" "unprognostic (2.44e-1)" "unprognostic (2.38e-1)" "unprognostic (7.62e-2)" "unprognostic (6.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.00e-1)" "unprognostic (4.15e-1)" "potential prognostic unfavorable (1.25e-4)" "unprognostic (1.93e-2)" "unprognostic (4.80e-2)" "potential prognostic unfavorable (3.24e-4)" "unprognostic (3.87e-3)" "unprognostic (6.91e-3)" "unprognostic (2.38e-3)" "potential prognostic unfavorable (7.48e-7)" "unprognostic (5.96e-2)" "unprognostic (6.43e-2)" "unprognostic (1.31e-1)" "unprognostic (2.53e-1)" "unprognostic (7.31e-3)" "unprognostic (8.01e-2)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (1.54e-1)" "unprognostic (3.77e-2)" "unprognostic (1.46e-1)" "unprognostic (2.10e-1)" "unprognostic (8.19e-2)" "unprognostic (8.31e-2)" TUBB1 dJ543J19.4 ENSG00000101162 "Tubulin beta 1 class VI" Q9H4B7 20 59019429-59026654 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.0;lymphoid tissue: 4.0" "Cell type enriched" "Detected in some" 9 "Platelets: 7732.1" "Cell type enriched" "Detected in many" 9 "Platelets: 7732.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 17 "basophil: 63.2;neutrophil: 26.0" "Lineage enriched" "Detected in many" 24 "granulocytes: 63.2" "Cancer enhanced" "Detected in some" "Leukemia: 2.6" "Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Cell type enhanced" "Detected in many" "Hepatocytes: 1365887.4;Neutrophils: 3053293.3" "Group enriched" "Detected in many" "bone marrow: 350832143.1;lymphoid tissue: 600479014.0" "CAB004286, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA 100000000 "Cluster 21: Neutrophils - Unknown function" "Cluster 29: Lymphoid tissue & Bone marrow - Innate immune response" "Cluster 6: Non-specific - Immune response" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" 19 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB004286: , HPA043640: , HPA046280: " "unprognostic (8.33e-2)" "unprognostic (8.05e-2)" "unprognostic (5.68e-2)" "unprognostic (3.40e-2)" TUBB2A "dJ40E16.7, TUBB, TUBB2" ENSG00000137267 "Tubulin beta 2A class IIa" Q13885 6 3153497-3157544 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "brain: 541.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 244.0;Breast myoepithelial cells: 296.2;Epididymal principal cells: 270.5;Esophageal apical cells: 539.0;Esophageal suprabasal cells: 413.6;Ocular epithelial cells: 239.1;Other brain neurons: 381.2;Platelets: 315.1;Retinal horizontal cells: 264.4;Suprabasal keratinocytes: 422.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 539.0;Suprabasal cells: 422.4" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 304.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "B-cells: 3.2;monocytes: 1.6;T-cells: 3.2" "Cancer enhanced" "Detected in all" "testis cancer: 336.7" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Kidney - Macrophages, Minor Salivary Gland - Minor salivary gland basal cells, Prostate - Smooth muscle cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 908061423.0" "Tissue enriched" "Detected in all" "cerebral cortex: 880987611.0" "CAB015339, HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 24: Neurons - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 98: Neurons - Neurotransmission & signaling" 70 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB015339: , HPA043640: , HPA046280: " "unprognostic (4.09e-3)" "unprognostic (1.81e-1)" "unprognostic (1.62e-1)" "unprognostic (5.17e-2)" "unprognostic (3.24e-1)" "unprognostic (8.04e-2)" "unprognostic (2.86e-2)" "unprognostic (1.58e-1)" "unprognostic (5.85e-2)" "unprognostic (3.22e-2)" "unprognostic (3.14e-1)" "potential prognostic unfavorable (5.26e-5)" "unprognostic (1.35e-1)" "unprognostic (2.45e-3)" "unprognostic (1.88e-1)" "unprognostic (3.87e-2)" "unprognostic (1.63e-2)" "unprognostic (2.16e-1)" "unprognostic (1.55e-1)" "unprognostic (1.61e-2)" "unprognostic (3.59e-1)" "unprognostic (8.80e-3)" "unprognostic (3.90e-2)" "unprognostic (1.71e-3)" "unprognostic (1.27e-2)" "unprognostic (3.49e-1)" "unprognostic (4.03e-3)" "unprognostic (1.17e-2)" "unprognostic (1.57e-1)" "unprognostic (4.80e-3)" "unprognostic (4.12e-2)" TUBB2B "bA506K6.1, DKFZp566F223, MGC8685" ENSG00000137285 "Tubulin beta 2B class IIb" Q9BVA1 6 3223324-3231730 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 596.1" "Cell type enhanced" "Detected in many" "Astrocytes: 159.3;Bergmann glia: 372.8;Breast myoepithelial cells: 193.7;Ependymal cells: 100.9;Epididymal principal cells: 380.9;Melanocytes: 135.3;Müller glia: 679.0;Myosatellite cells: 110.6;Retinal horizontal cells: 222.4;Schwann cells: 130.8" "Cell type enhanced" "Detected in many" "Glial cells: 679.0;Neuronal cells: 222.4;Reproductive supporting cells: 380.9;Secretory gland support: 193.7" "Cell type enhanced" "Detected in all" "Bergmann glia: 539.4" "Cancer enriched" "Detected in all" 12 "Glioblastoma Multiforme (TCGA): 842.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 461.5" "Adrenal gland - Adrenal medulla cells, Breast - Breast myoepithelial cells, Kidney - Ascending Loop of Henle cells, Minor Salivary Gland - Minor salivary glandular cells, Skeletal muscle - Fibroblasts, Stomach - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 26832370.9;Distal tubules: 29121213.1;Microglia and Neuropil: 19189668.1;Neurons: 15807513.9" "Tissue enhanced" "Detected in all" "cerebral cortex: 120933737.1" "HPA043640, HPA046280" Supported Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 11: Muller glia cells - Retinal homeostasis" 45 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (5.37e-2)" "unprognostic (2.49e-1)" "unprognostic (2.88e-2)" "unprognostic (2.16e-2)" "unprognostic (2.11e-1)" "unprognostic (3.45e-2)" "unprognostic (7.45e-2)" "unprognostic (7.01e-2)" "unprognostic (1.26e-1)" "unprognostic (6.60e-2)" "validated prognostic unfavorable (7.45e-4)" "validated prognostic unfavorable (2.60e-4)" "unprognostic (3.12e-1)" "unprognostic (7.72e-2)" "unprognostic (1.48e-2)" "unprognostic (3.72e-1)" "unprognostic (4.15e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-3)" "unprognostic (4.59e-1)" "unprognostic (1.33e-1)" "unprognostic (5.08e-3)" "unprognostic (4.02e-1)" "unprognostic (2.61e-1)" "unprognostic (1.75e-1)" "unprognostic (1.59e-1)" "unprognostic (1.11e-1)" "unprognostic (1.09e-2)" "unprognostic (3.84e-1)" "potential prognostic unfavorable (1.39e-6)" "unprognostic (4.25e-3)" TUBB3 "beta-4, CFEOM3, CFEOM3A, FEOM3" ENSG00000258947 "Tubulin beta 3 class III" Q13509 16 89921392-89938761 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, FDA approved drug targets, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 344.3" "Group enriched" "Detected in some" 8 "Brain excitatory neurons: 88.3;Brain inhibitory neurons: 88.8;Other brain neurons: 290.9" "Cell type enriched" "Detected in some" 15 "Neuronal cells: 290.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "naive B-cell: 2.5" "Lineage enriched" "Detected in single" 9 "B-cells: 2.5" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Colon - Colon enteroendocrine cells, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 671139358.7;Microglia and Neuropil: 569537832.7;Neurons: 482636461.2" "Tissue enriched" "Detected in all" "cerebral cortex: 670930937.1" "HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA 71000000 "Cluster 10: Brain - Synaptic signal transduction" "Cluster 45: Non-specific - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 98: Neurons - Neurotransmission & signaling" 58 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (1.26e-1)" "unprognostic (3.05e-2)" "unprognostic (4.21e-1)" "unprognostic (1.25e-3)" "unprognostic (1.28e-1)" "unprognostic (2.72e-1)" "potential prognostic unfavorable (9.70e-4)" "potential prognostic favorable (3.37e-4)" "unprognostic (4.82e-2)" "unprognostic (1.69e-1)" "validated prognostic unfavorable (3.73e-7)" "validated prognostic unfavorable (1.17e-6)" "unprognostic (1.67e-2)" "unprognostic (1.83e-3)" "unprognostic (9.74e-2)" "unprognostic (2.12e-3)" "unprognostic (1.53e-2)" "unprognostic (2.32e-2)" "unprognostic (1.03e-3)" "unprognostic (5.63e-2)" "unprognostic (1.44e-1)" "unprognostic (3.90e-2)" "potential prognostic unfavorable (1.16e-5)" "unprognostic (6.70e-3)" "unprognostic (7.69e-2)" "unprognostic (4.67e-2)" "unprognostic (8.79e-2)" "unprognostic (5.34e-3)" "unprognostic (1.26e-1)" "unprognostic (2.37e-1)" "unprognostic (6.08e-2)" TUBB4A "beta-5, DYT4, TUBB4" ENSG00000104833 "Tubulin beta 4A class IVa" P04350 19 6494319-6502848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Dystonia, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 1155.6" "Cell type enhanced" "Detected in some" "Adrenal cortex cells: 39.3;Adrenal medulla cells: 31.9;Brain excitatory neurons: 96.2;Brain inhibitory neurons: 37.1;Epididymal efferent duct absorptive cells: 20.3;Melanocytes: 35.2;Müller glia: 35.0;Oligodendrocytes: 184.3;Other brain neurons: 45.3;Retinal pigment epithelial cells: 85.3;Sertoli cells: 26.8" "Cell type enhanced" "Detected in many" "Adrenal endocrine cells: 39.3;Glial cells: 184.3;Neuronal cells: 96.2;Pigment cells: 85.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 196.1;oligodendrocyte: 221.3;upper rhombic lip: 191.0" "Group enriched" "Detected in many" 4 "Glioblastoma Multiforme (TCGA): 145.4;Skin Cutaneous Melanoma (TCGA): 232.4;Testicular Germ Cell Tumor (TCGA): 150.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 19 "B-cells: 3.8;T-cells: 5.4" "Cancer enhanced" "Detected in many" "skin cancer: 55.0" "Adrenal gland - Adrenal cortex cells, Colon - Colon enteroendocrine cells, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 1758911553.6;Microglia and Neuropil: 1430094016.4;Neurons: 971003740.0" "Tissue enriched" "Detected in all" "cerebral cortex: 960725596.0" "CAB010768, HPA043640, HPA046280" Approved Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA 100000000 "Cluster 24: Non-specific - Transcription" "Cluster 27: Cerebellum - Synaptic function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 2: Cerebellar granular cells - Neuronal signaling" 42 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB010768: , HPA043640: , HPA046280: " "unprognostic (1.18e-2)" "unprognostic (5.93e-2)" "unprognostic (6.56e-3)" "unprognostic (2.98e-1)" "unprognostic (5.14e-2)" "unprognostic (1.50e-1)" "unprognostic (4.89e-2)" "unprognostic (4.12e-2)" "unprognostic (1.56e-1)" "unprognostic (7.55e-3)" "unprognostic (5.13e-2)" "unprognostic (7.25e-2)" "potential prognostic favorable (9.68e-4)" "unprognostic (1.05e-1)" "unprognostic (1.80e-3)" "unprognostic (1.01e-1)" "potential prognostic unfavorable (1.40e-4)" "unprognostic (5.37e-2)" "unprognostic (6.72e-2)" "unprognostic (2.66e-1)" "unprognostic (6.76e-2)" "unprognostic (1.91e-1)" "potential prognostic unfavorable (2.36e-4)" TUBB4B "Beta2, TUBB2C" ENSG00000188229 "Tubulin beta 4B class IVb" P68371 9 137241287-137243707 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Deafness, Disease variant, FDA approved drug targets, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 2019.1;Esophageal apical cells: 2023.6;Fallopian tube ciliated cells: 2624.7;Late primary spermatocytes: 3642.4;Late spermatids: 4003.9;Respiratory ciliated cells: 2676.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 2023.6;Ciliated cells: 2676.7;Spermatogenic cell types: 4003.9" "Cell type enhanced" "Detected in all" "ependymal cell: 488.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Adrenal gland - Adrenal cortex cells, Breast - Adipocytes (Breast), Kidney - Macrophages, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Collecting ducts: 566032277.2" "Tissue enhanced" "Detected in all" "cerebral cortex: 328190249.1" "CAB010880, HPA043640, HPA046280" Enhanced Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes Yes 130000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 44: Non-specific - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 20: Non-specific - Transcription regulation" 173 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "CAB010880: , HPA043640: , HPA046280: " "unprognostic (2.76e-2)" "unprognostic (2.58e-1)" "unprognostic (1.01e-2)" "unprognostic (7.18e-2)" "unprognostic (2.64e-1)" "unprognostic (3.59e-2)" "unprognostic (1.98e-1)" "unprognostic (7.37e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (2.21e-1)" "unprognostic (5.77e-2)" "potential prognostic unfavorable (3.19e-4)" "unprognostic (5.16e-3)" "unprognostic (6.06e-3)" "unprognostic (6.26e-2)" "unprognostic (3.00e-2)" "unprognostic (1.89e-1)" "unprognostic (2.38e-2)" "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (1.74e-1)" "unprognostic (6.58e-2)" "unprognostic (2.32e-1)" "unprognostic (2.97e-1)" "unprognostic (1.14e-2)" "unprognostic (4.60e-2)" "potential prognostic favorable (2.12e-4)" "unprognostic (4.44e-2)" TUBB6 "HsT1601, MGC4083" ENSG00000176014 "Tubulin beta 6 class V" Q9BUF5 18 12307669-12344320 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 376.0;Cardiomyocytes: 321.8;Decidual stromal cells: 381.5;Esophageal apical cells: 1568.3;Esophageal suprabasal cells: 484.6;Extravillous trophoblasts: 829.5;Smooth muscle cells: 326.6" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1568.3;Trophoblast cells: 829.5" "Cell type enhanced" "Detected in all" "endothelial cell: 72.1;pericyte: 50.2;vascular associated smooth muscle cell: 104.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 157.2" "Group enriched" "Detected in many" 6 "B-cells: 58.8;dendritic cells: 157.2" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Colon - Smooth muscle cells, Prostate - Smooth muscle cells, Skeletal muscle - Fibroblasts, Spleen - Fibroblasts_1" "Region enriched" "Detected in many" 6 "olfactory bulb: 19.9" "Region enhanced" "Detected in all" "spinal cord: 14.0" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 30249032.0" "Tissue enriched" "Detected in all" "cerebral cortex: 1072790819.4" "HPA043640, HPA046280" Approved Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes Yes 51000000 "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 12: Non-specific - Vasculature" "Cluster 72: Neuronal - Signal transduction" "Cluster 21: Extravillous trophoblasts - Placental invasion & endocrine regulatio" 47 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (3.00e-2)" "unprognostic (6.47e-2)" "unprognostic (2.30e-2)" "unprognostic (4.26e-3)" "unprognostic (1.38e-2)" "unprognostic (1.70e-1)" "unprognostic (7.82e-2)" "unprognostic (6.95e-2)" "unprognostic (1.01e-3)" "unprognostic (2.51e-1)" "unprognostic (3.74e-2)" "unprognostic (4.12e-2)" "unprognostic (3.95e-3)" "unprognostic (6.25e-2)" "unprognostic (6.13e-2)" "unprognostic (3.65e-3)" "unprognostic (5.96e-3)" "unprognostic (7.86e-2)" "unprognostic (5.77e-2)" "unprognostic (5.29e-3)" "unprognostic (1.22e-1)" "unprognostic (4.33e-2)" "unprognostic (4.69e-3)" "unprognostic (2.68e-1)" "unprognostic (1.07e-2)" "unprognostic (3.94e-2)" "unprognostic (4.81e-2)" "unprognostic (1.84e-3)" "unprognostic (2.27e-1)" "unprognostic (3.48e-2)" "potential prognostic unfavorable (5.09e-4)" TUBB8 bA631M21.2 ENSG00000261456 "Tubulin beta 8 class VIII" Q3ZCM7 10 46888-74163 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "ovary: 2.3;testis: 1.7" "Cell type enriched" "Detected in some" 30 "Oocytes: 534.2" "Cell type enriched" "Detected in some" 30 "Oocytes: 534.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 9.6" "Cancer enriched" "Detected in single" 5 "Testicular Germ Cell Tumor (TCGA): 4.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in some" "Oocytes: 16379598.3" "Group enriched" "Detected in many" "bone marrow: 553692.4;cerebral cortex: 598097.8;fallopian tube: 1424438.5;ovary: 463090.1" "HPA043640, HPA046280" Uncertain Supported "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 75: Ovary - Mixed function" "Cluster 11: Neuronal - Sensory perception" "Cluster 41: Oocytes - Oogenesis" 103 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" TUBB8B TUBB8P12 ENSG00000173213 "Tubulin beta 8B" A6NNZ2 18 47221-73545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "ovary: 1.5;testis: 4.3" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 39.8;Early primary spermatocytes: 46.6;Oocytes: 161.2" "Group enriched" "Detected in some" 33 "Oocytes: 161.2;Spermatogenic cell types: 46.6" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 4.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1112 "Oocytes: 111244.3" "Tissue enriched" "Detected in single" 328 "skeletal muscle: 32846.6" "HPA043640, HPA046280" Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Primary cilium tip,Basal body,Flagellar centriole,Principal piece,End piece" Yes NA "Cluster 79: Testis - Spermatogenesis" "Cluster 18: Liver cancer - Metabolism" "Cluster 41: Oocytes - Oogenesis" 6 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Primary cilium tip, Basal body, Flagellar centriole, Principal piece, End piece" "HPA043640: , HPA046280: " "unprognostic (2.75e-1)" "unprognostic (1.77e-1)" TUBGCP5 "GCP5, KIAA1899" ENSG00000275835 "Tubulin gamma complex associated protein 5" Q96RT8 15 22983192-23039572 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 31.7;Brain inhibitory neurons: 36.3;Distal convoluted tubule cells: 34.2;Loop of henle epithelial cells: 33.0;Microglia: 42.1;Oligodendrocytes: 37.5;Other brain neurons: 37.5;Proximal tubule cells: 34.2;Renal collecting duct principal cells: 33.9;Renal connecting tubule cells: 32.9" "Cell type enhanced" "Detected in many" "Ductal cells: 33.9;Glial cells: 42.1;Neuronal cells: 37.5;Renal nephron cells: 34.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 307195.7;Oocytes: 306121.8;T-cells: 423585.6" "Tissue enriched" "Detected in some" "fallopian tube: 154577.4" "HPA039366, HPA040366" Supported Supported "Primary cilium,Primary cilium transition zone,Centrosome,Basal body,Cytosol" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 58: Non-specific - Nuclear processes" "Cluster 102: Non-specific - Mixed function" 27 "Centrosome, Basal body" "Primary cilium, Primary cilium transition zone, Cytosol" "HPA039366: , HPA040366: " "unprognostic (6.18e-2)" "unprognostic (3.36e-3)" "unprognostic (2.99e-2)" "unprognostic (4.01e-1)" "unprognostic (5.11e-2)" "unprognostic (1.60e-1)" "unprognostic (1.27e-1)" "unprognostic (2.23e-1)" "unprognostic (2.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.10e-1)" "unprognostic (3.17e-1)" "unprognostic (8.34e-2)" "unprognostic (1.63e-1)" "unprognostic (2.10e-1)" "unprognostic (8.00e-2)" "unprognostic (9.33e-2)" "unprognostic (1.17e-2)" "unprognostic (1.22e-1)" "unprognostic (2.02e-1)" "unprognostic (3.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.33e-1)" "unprognostic (1.54e-1)" "unprognostic (1.06e-2)" "unprognostic (1.15e-2)" "unprognostic (1.11e-1)" "unprognostic (1.93e-1)" TUFM "EF-TuMT, EFTu" ENSG00000178952 "Tu translation elongation factor, mitochondrial" P49411 16 28842411-28846348 "Disease related genes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Elongation factor, Hydrolase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 529.6;Late spermatids: 1008.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 1008.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA018991, HPA024087, CAB075730, CAB075731, CAB075732" Enhanced Enhanced Mitochondria NA NA 550000 "Cluster 13: Non-specific - Mitochondria" "Cluster 52: Non-specific - Cellular respiration" "Cluster 21: Non-specific - Metabolism" "Cluster 54: Non-specific - Transcription" "Cluster 97: Non-specific - Cellular respiration" 71 Mitochondria "CAB075730: , CAB075731: , CAB075732: , HPA018991: , HPA024087: " "unprognostic (1.34e-3)" "unprognostic (9.06e-2)" "unprognostic (5.85e-2)" "unprognostic (2.89e-1)" "unprognostic (8.62e-2)" "unprognostic (1.78e-2)" "unprognostic (1.36e-1)" "unprognostic (1.46e-1)" "unprognostic (2.89e-2)" "unprognostic (1.82e-1)" "potential prognostic favorable (1.17e-4)" "unprognostic (1.46e-1)" "unprognostic (1.06e-2)" "unprognostic (7.78e-3)" "unprognostic (1.72e-2)" "unprognostic (9.80e-2)" "unprognostic (4.38e-2)" "unprognostic (1.58e-1)" "unprognostic (3.84e-1)" "unprognostic (1.34e-1)" "unprognostic (1.04e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (2.28e-1)" "unprognostic (2.24e-2)" "unprognostic (3.79e-2)" "unprognostic (5.55e-2)" "unprognostic (2.74e-1)" "unprognostic (7.45e-2)" "unprognostic (4.26e-3)" "unprognostic (4.01e-2)" TULP3 TUBL3 ENSG00000078246 "TUB like protein 3" O75386 12 2877223-2941138 "Disease related genes, Predicted intracellular proteins" "Developmental protein" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Retinal horizontal cells: 180.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Testicular Germ Cell Tumor (TCGA): 76.6" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in some" 49687 "fallopian tube: 6176660.3;ovary: 3760810.6" "HPA015285, HPA018496" Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle,Primary cilium,Primary cilium transition zone,Basal body" "Intracellular and membrane" "Developmental protein" Yes NA "Cluster 14: Non-specific - Unknown function" "Cluster 75: Ovary - Mixed function" "Cluster 55: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 70 "Nucleoplasm, Primary cilium" "Nucleoli, Plasma membrane, Mitotic spindle, Primary cilium transition zone, Basal body" "HPA015285: , HPA018496: " "unprognostic (1.58e-2)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (5.39e-2)" "unprognostic (1.38e-1)" "unprognostic (1.88e-3)" "unprognostic (1.67e-1)" "unprognostic (1.27e-1)" "unprognostic (1.94e-2)" "unprognostic (6.20e-3)" "unprognostic (2.28e-2)" "unprognostic (6.01e-2)" "unprognostic (3.61e-1)" "potential prognostic unfavorable (4.20e-5)" "unprognostic (3.16e-2)" "unprognostic (4.20e-2)" "potential prognostic unfavorable (6.73e-4)" "unprognostic (8.01e-2)" "unprognostic (5.19e-2)" "unprognostic (1.04e-1)" "unprognostic (1.30e-1)" "unprognostic (4.09e-2)" "unprognostic (5.94e-2)" "unprognostic (1.96e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-3)" "unprognostic (7.51e-2)" "unprognostic (1.29e-1)" "unprognostic (1.84e-1)" "unprognostic (3.36e-2)" "unprognostic (2.64e-2)" TULP4 "KIAA1397, TUSP" ENSG00000130338 "TUB like protein 4" Q9NRJ4 6 158232236-158511828 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 409.9;Oligodendrocytes: 322.7" "Cell type enhanced" "Detected in many" "Neuronal cells: 409.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA005445 Approved Approved "Acrosome,Principal piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 7 "Principal piece" Acrosome "HPA005445: " "unprognostic (1.40e-2)" "potential prognostic unfavorable (9.08e-4)" "unprognostic (1.99e-2)" "unprognostic (1.92e-2)" "unprognostic (1.41e-1)" "unprognostic (2.54e-3)" "unprognostic (2.63e-1)" "potential prognostic favorable (3.58e-5)" "unprognostic (1.65e-1)" "unprognostic (2.41e-1)" "potential prognostic favorable (7.75e-6)" "unprognostic (6.52e-3)" "unprognostic (1.42e-1)" "unprognostic (2.31e-2)" "unprognostic (2.90e-2)" "unprognostic (2.00e-1)" "unprognostic (3.26e-1)" "unprognostic (1.87e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-2)" "unprognostic (8.59e-2)" "unprognostic (4.01e-2)" "unprognostic (1.33e-1)" "unprognostic (1.68e-1)" "unprognostic (2.57e-3)" "unprognostic (1.58e-3)" "unprognostic (2.35e-1)" "unprognostic (3.23e-1)" "unprognostic (1.90e-1)" "unprognostic (3.91e-1)" "unprognostic (3.48e-1)" TUT4 "KIAA0191, PAPD3, TENT3A, ZCCHC11" ENSG00000134744 "Terminal uridylyl transferase 4" Q5TAX3 1 52408282-52553487 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "RNA-mediated gene silencing" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Corticotrophs: 707.8;Myonuclei: 736.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 869004.7" "Tissue enriched" "Detected in single" 35377 "lymphoid tissue: 3537701.5" "HPA027412, HPA027973" Supported Supported Nucleoli,Cytosol NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 4 Cytosol Nucleoli "HPA027412: , HPA027973: " "unprognostic (2.75e-1)" "unprognostic (6.68e-2)" "unprognostic (3.47e-1)" "unprognostic (8.00e-3)" "unprognostic (2.00e-1)" "unprognostic (8.41e-2)" "unprognostic (5.29e-2)" "unprognostic (2.90e-2)" "unprognostic (2.55e-3)" "unprognostic (1.01e-1)" "unprognostic (1.91e-2)" "unprognostic (4.83e-2)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.84e-1)" "unprognostic (7.64e-2)" "unprognostic (4.25e-2)" "unprognostic (1.53e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "potential prognostic favorable (3.51e-4)" "unprognostic (3.02e-3)" "unprognostic (2.08e-3)" "unprognostic (8.25e-2)" "unprognostic (1.52e-1)" "unprognostic (8.05e-2)" "unprognostic (2.83e-1)" "unprognostic (3.99e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-1)" TWIST2 "bHLHa39, Dermo-1, DERMO1" ENSG00000233608 "Twist family bHLH transcription factor 2" Q8WVJ9 2 238848032-238910534 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 81.7" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 2.6;Endometrial stromal cells: 2.7;Fibroblasts: 11.0;Microglia: 24.2;Papillary tip epithelial cells: 2.6;Peritubular myoid cells: 2.2;Smooth muscle cells: 5.7" "Cell type enhanced" "Detected in some" "Fibroblasts: 11.0;Glial cells: 24.2;Smooth muscle cells: 5.7" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 34.9;fibroblast: 51.9;vascular associated smooth muscle cell: 18.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 24 "eosinophil: 4.7" "Lineage enriched" "Detected in single" 47 "granulocytes: 4.7" "Cancer enhanced" "Detected in many" "Sarcoma: 12.0" "Adrenal gland - Fibroblasts, Kidney - Fibroblasts, Prostate - Fibroblasts, Spleen - Fibroblasts_1" "Low region specificity" "Detected in single" "Region enriched" "Detected in single" 7 "spinal cord: 3.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA062870 Supported Nucleoplasm,Nucleoli NA NA "Cluster 75: Ovary - Mixed function" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 44: Connective tissue cells - ECM organization" "Cluster 105: Non-specific - Mixed function" 19 Nucleoplasm Nucleoli "HPA062870: " "unprognostic (2.35e-1)" "unprognostic (1.01e-2)" "unprognostic (1.10e-1)" "unprognostic (2.24e-1)" "unprognostic (1.90e-1)" "unprognostic (1.09e-2)" "unprognostic (1.50e-2)" "unprognostic (3.08e-2)" "unprognostic (4.70e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (3.52e-2)" "unprognostic (1.44e-1)" "unprognostic (3.67e-3)" "unprognostic (8.55e-3)" "unprognostic (6.52e-3)" "unprognostic (1.08e-1)" "unprognostic (8.67e-2)" TWSG1 TSG ENSG00000128791 "Twisted gastrulation BMP signaling modulator 1" Q9GZX9 18 9334767-9402420 "Predicted secreted proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Renal collecting duct principal cells: 203.8;Respiratory ionocytes: 185.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Fibroblasts, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in many" "ovary: 3820333.5" HPA014898 Uncertain Supported Centrosome,Cytosol "Secreted - unknown location" "Developmental protein" No No 1100000 "Cluster 30: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Transcription" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 62: Smooth muscle cells - Muscle contraction" 10 "Centrosome, Cytosol" "HPA014898: " "unprognostic (1.16e-1)" "unprognostic (2.33e-1)" "unprognostic (2.66e-1)" "unprognostic (1.37e-2)" "unprognostic (1.33e-1)" "unprognostic (7.80e-2)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (6.94e-4)" "unprognostic (2.80e-1)" "unprognostic (3.27e-2)" "unprognostic (3.79e-3)" "unprognostic (1.21e-1)" "unprognostic (1.60e-2)" "unprognostic (7.14e-2)" "unprognostic (2.10e-2)" "unprognostic (7.43e-3)" "unprognostic (3.19e-2)" "unprognostic (1.49e-2)" "unprognostic (1.92e-1)" "unprognostic (3.01e-2)" "unprognostic (6.02e-3)" "unprognostic (3.10e-2)" "unprognostic (8.80e-2)" "unprognostic (3.29e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (7.59e-2)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.51e-1)" "unprognostic (9.11e-2)" TXN "TRX, Trx80" ENSG00000136810 Thioredoxin P10599 9 110243810-110256507 "Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transcription, Transcription regulation, Transport" Activator Allergen "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1237.8" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 9041.3;Esophageal basal cells: 4687.0;Esophageal suprabasal cells: 15115.7;Gastric progenitor cells: 5418.9;Suprabasal keratinocytes: 3556.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 9041.3;Proliferating cells: 5418.9;Suprabasal cells: 15115.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 1646.2;granulocytes: 1359.5" "Low cancer specificity" "Detected in all" "Kidney - Proximal tubular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB008678, HPA047478, HPA055752" Enhanced Enhanced Nucleoplasm,Cytosol "Intracellular and membrane" Transport NA NA 33000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 85: Squamous epithelial cells - Keratinization" 61 "Nucleoplasm, Cytosol" "CAB008678: , HPA047478: , HPA055752: " "unprognostic (1.97e-1)" "unprognostic (2.02e-3)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.40e-1)" "unprognostic (1.87e-1)" "unprognostic (5.70e-3)" "unprognostic (2.69e-2)" "unprognostic (2.49e-2)" "unprognostic (2.47e-2)" "unprognostic (3.08e-2)" "unprognostic (9.09e-2)" "unprognostic (1.79e-3)" "unprognostic (3.58e-3)" "potential prognostic unfavorable (2.88e-4)" "potential prognostic unfavorable (1.74e-4)" "unprognostic (2.44e-1)" "unprognostic (2.96e-1)" "unprognostic (1.30e-1)" "unprognostic (2.08e-2)" "unprognostic (1.22e-1)" "unprognostic (3.50e-3)" "unprognostic (3.09e-1)" "unprognostic (1.17e-1)" "unprognostic (3.92e-1)" "unprognostic (8.76e-2)" "unprognostic (1.11e-1)" "unprognostic (6.89e-2)" "unprognostic (1.81e-1)" "unprognostic (6.90e-2)" "unprognostic (3.67e-3)" TXN2 MT-TRX ENSG00000100348 "Thioredoxin 2" Q99757 22 36467046-36481640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Electron transport, Transport" "Neurodegeneration, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal suprabasal cells: 293.5;Extravillous trophoblasts: 341.2;Oocytes: 331.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 4799267.0" "Low tissue specificity" "Detected in all" "HPA000994, CAB008681" Approved Enhanced Mitochondria No No 3600000 "Cluster 13: Non-specific - Mitochondria" "Cluster 76: Non-specific - Metabolism" "Cluster 19: Astrocytes - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" 72 Mitochondria "CAB008681: , HPA000994: " "unprognostic (1.27e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (2.52e-1)" "potential prognostic favorable (5.57e-4)" "unprognostic (7.06e-2)" "unprognostic (1.60e-1)" "unprognostic (3.21e-1)" "unprognostic (1.38e-2)" "unprognostic (1.27e-2)" "unprognostic (2.88e-3)" "unprognostic (1.29e-1)" "potential prognostic favorable (1.98e-5)" "unprognostic (3.26e-3)" "unprognostic (7.58e-3)" "unprognostic (6.95e-2)" "unprognostic (2.91e-1)" "unprognostic (3.52e-3)" "unprognostic (8.85e-3)" "unprognostic (3.91e-2)" "unprognostic (3.09e-1)" "unprognostic (1.83e-1)" "unprognostic (1.52e-1)" "potential prognostic favorable (8.85e-4)" "unprognostic (7.35e-3)" "unprognostic (5.69e-2)" "unprognostic (2.07e-1)" "unprognostic (5.34e-2)" "unprognostic (1.95e-1)" "unprognostic (1.28e-1)" "unprognostic (7.93e-2)" TXNDC11 EFP1 ENSG00000153066 "Thioredoxin domain containing 11" Q6PKC3 16 11679083-11742857 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 308.7;Plasma cells: 588.1" "Cell type enhanced" "Detected in all" "Plasma cells: 588.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 119.2;Myeloma: 175.3" "Breast - Plasma cells, Prostate - Prostate glandular cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 1087082.7;Pancreatic islets: 1343255.9" "Tissue enriched" "Detected in some" "bone marrow: 7981048.0" "HPA041174, HPA041390" Supported Supported "Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 8 "Plasma membrane, Cytosol" "HPA041174: , HPA041390: " "unprognostic (6.23e-1)" "unprognostic (9.28e-2)" "unprognostic (1.75e-1)" "unprognostic (1.64e-2)" "unprognostic (6.02e-2)" "unprognostic (1.86e-1)" "unprognostic (1.01e-1)" "unprognostic (3.73e-2)" "unprognostic (4.05e-2)" "unprognostic (6.48e-2)" "potential prognostic favorable (1.24e-6)" "unprognostic (2.45e-1)" "unprognostic (1.04e-1)" "unprognostic (2.22e-1)" "unprognostic (2.39e-1)" "unprognostic (1.02e-3)" "unprognostic (2.69e-2)" "potential prognostic unfavorable (6.48e-4)" "unprognostic (2.06e-1)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (6.37e-2)" "unprognostic (3.28e-2)" "unprognostic (3.17e-1)" "unprognostic (6.63e-2)" "unprognostic (9.27e-2)" "unprognostic (2.03e-1)" "unprognostic (2.49e-2)" "unprognostic (1.88e-2)" "unprognostic (1.83e-1)" "unprognostic (3.12e-2)" TXNRD2 "SELZ, TR, TR3, TRXR2" ENSG00000184470 "Thioredoxin reductase 2" Q9NNW7 22 19875517-19941820 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 94.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Liver - Hepatocytes, Prostate - Prostate glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "liver: 35331060.8" "CAB002007, HPA003323" Supported Approved Mitochondria,Cytosol NA NA 450000 "Cluster 25: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 5: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 4 "Mitochondria, Cytosol" "CAB002007: , HPA003323: " "unprognostic (2.45e-3)" "unprognostic (4.27e-2)" "unprognostic (1.91e-1)" "unprognostic (1.02e-2)" "unprognostic (2.69e-2)" "unprognostic (6.31e-3)" "unprognostic (5.27e-2)" "unprognostic (1.05e-1)" "unprognostic (2.01e-2)" "unprognostic (5.36e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (1.04e-1)" "potential prognostic favorable (3.07e-6)" "unprognostic (3.23e-1)" "unprognostic (1.07e-1)" "unprognostic (2.65e-1)" "unprognostic (2.83e-1)" "unprognostic (3.04e-2)" "unprognostic (2.22e-1)" "unprognostic (1.16e-1)" "unprognostic (9.67e-2)" "unprognostic (5.88e-2)" "unprognostic (1.26e-3)" "unprognostic (6.64e-2)" "unprognostic (5.30e-2)" "unprognostic (2.08e-2)" "unprognostic (7.06e-2)" "unprognostic (2.51e-1)" "unprognostic (1.83e-1)" "unprognostic (7.04e-2)" "unprognostic (1.49e-1)" TYK2 JTK1 ENSG00000105397 "Tyrosine kinase 2" P29597 19 10350533-10380608 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 141.2" "Cell type enhanced" "Detected in many" "Neutrophils: 141.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 12419899.9" "Tissue enhanced" "Detected in many" "lymphoid tissue: 2811520.3" HPA005157 Uncertain Approved Cytosol NA NA "Cluster 26: Monocytes - Plasma membrane proteins" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 28 Cytosol "HPA005157: " "unprognostic (2.25e-1)" "unprognostic (2.70e-2)" "unprognostic (3.15e-2)" "potential prognostic favorable (5.22e-5)" "unprognostic (1.49e-1)" "unprognostic (3.40e-1)" "unprognostic (7.77e-2)" "unprognostic (1.07e-1)" "unprognostic (2.48e-3)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (5.44e-11)" "unprognostic (1.03e-1)" "unprognostic (1.94e-2)" "unprognostic (6.71e-2)" "unprognostic (1.13e-1)" "unprognostic (2.53e-1)" "unprognostic (1.28e-1)" "unprognostic (1.31e-2)" "unprognostic (2.30e-2)" "unprognostic (6.73e-3)" "unprognostic (2.93e-2)" "potential prognostic favorable (1.74e-4)" "unprognostic (4.62e-3)" "unprognostic (5.63e-2)" "unprognostic (2.42e-1)" "unprognostic (2.68e-2)" "unprognostic (1.62e-1)" "unprognostic (6.70e-2)" "unprognostic (7.56e-2)" "unprognostic (2.36e-1)" "unprognostic (1.87e-2)" TYMP "ECGF1, MNGIE" ENSG00000025708 "Thymidine phosphorylase" P19971 22 50525752-50530032 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Glycosyltransferase, Growth factor, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neuropathy, Primary mitochondrial disease, Progressive external ophthalmoplegia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "cDC: 355.1;Esophageal apical cells: 220.7;Esophageal suprabasal cells: 240.4;Extravillous trophoblasts: 378.0;Macrophages: 281.0;monocytes: 586.6;Neutrophils: 409.7" "Cell type enhanced" "Detected in all" "Mononuclear phagocytes: 586.6;Neutrophils: 409.7;Trophoblast cells: 378.0" "Group enriched" "Detected in many" 4 "central nervous system macrophage: 40.7;ependymal cell: 61.8;leukocyte: 74.7" "Cancer enhanced" "Detected in all" "Head and Neck Squamous Cell Carcinoma (TCGA): 543.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 137.0;eosinophil: 75.1;intermediate monocyte: 98.9;myeloid DC: 39.6;neutrophil: 115.9;non-classical monocyte: 77.6" "Group enriched" "Detected in all" 10 "dendritic cells: 39.6;granulocytes: 115.9;monocytes: 137.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 86.4" "Not detected" "Not detected" "Cell type enhanced" "Detected in all" "Macrophages: 78934535.2" "Tissue enhanced" "Detected in all" "lymphoid tissue: 175841641.8" "HPA000530, HPA001072, CAB002518" Enhanced Approved "Nuclear bodies,Golgi apparatus,Cytosol" NA NA 10000000 "Cluster 25: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 24 "Nuclear bodies, Golgi apparatus" Cytosol "CAB002518: , HPA000530: , HPA001072: " "unprognostic (2.42e-2)" "unprognostic (1.91e-2)" "unprognostic (2.41e-1)" "unprognostic (9.74e-2)" "unprognostic (3.82e-1)" "unprognostic (2.15e-1)" "unprognostic (2.22e-2)" "unprognostic (1.45e-1)" "unprognostic (5.38e-2)" "unprognostic (2.12e-1)" "unprognostic (5.27e-3)" "unprognostic (1.57e-3)" "unprognostic (4.90e-2)" "unprognostic (1.17e-1)" "unprognostic (6.49e-2)" "unprognostic (1.59e-1)" "unprognostic (1.68e-2)" "unprognostic (3.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.52e-1)" "unprognostic (7.57e-3)" "unprognostic (8.33e-2)" "unprognostic (4.26e-3)" "unprognostic (3.08e-1)" "unprognostic (3.29e-2)" "unprognostic (8.42e-2)" "unprognostic (7.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.63e-2)" "unprognostic (6.58e-3)" "unprognostic (3.02e-1)" TYRP1 "b-PROTEIN, CAS2, CATB, GP75, OCA3, TRP, TYRP" ENSG00000107165 "Tyrosinase related protein 1" P17643 9 12685439-12710285 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Melanin biosynthesis" "Monooxygenase, Oxidoreductase" "Albinism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "choroid plexus: 67.5;heart muscle: 56.0;skin 1: 137.2" "Group enriched" "Detected in some" 65 "Melanocytes: 4717.1;Retinal pigment epithelial cells: 2285.0" "Cell type enriched" "Detected in some" 88 "Pigment cells: 4717.1" "Cell type enriched" "Detected in some" 17 "choroid plexus epithelial cell: 38.6" "Cancer enriched" "Detected in many" 224 "Skin Cutaneous Melanoma (TCGA): 672.2" "Region enriched" "Detected in many" 16 "choroid plexus: 104.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "skin cancer: 576.9" "Heart muscle - Cardiomyocytes, Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Skin - Melanocytes" "Group enriched" "Detected in some" 5 "olfactory bulb: 4.6;thalamus: 1.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000937, CAB002520" Enhanced Approved Vesicles NA NA 50000 "Cluster 58: Skin - Keratinization" "Cluster 36: Choroid plexus - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 61: Schwann cells & Melanocytes - Mixed function" 4 Vesicles "CAB002520: , HPA000937: " "unprognostic (3.27e-2)" "unprognostic (3.13e-2)" "unprognostic (8.99e-2)" "unprognostic (7.18e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.04e-1)" "unprognostic (7.52e-2)" "unprognostic (1.87e-2)" "unprognostic (1.62e-1)" "unprognostic (1.84e-2)" "unprognostic (3.95e-1)" "unprognostic (6.66e-2)" TYW1 "FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W" ENSG00000198874 "TRNA-yW synthesizing protein 1 homolog" Q9NV66 7 66995173-67239514 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 350.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 3847 "Collecting ducts: 328195.9;Distal tubules: 273049.2;Granulosa cells: 490393.4;Pancreas epithelial cells: 286562.7;Pancreatic islets: 545343.3" "Tissue enriched" "Detected in single" 756 "lymphoid tissue: 75613.0" "HPA015535, HPA043136, HPA047029, HPA047052, HPA052097" Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 39: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 22 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA015535: , HPA043136: , HPA047029: , HPA047052: , HPA052097: " "unprognostic (3.19e-1)" "unprognostic (6.33e-2)" "unprognostic (2.22e-1)" "unprognostic (1.16e-1)" "unprognostic (3.51e-1)" "unprognostic (8.18e-2)" "unprognostic (1.82e-1)" "unprognostic (3.21e-2)" "unprognostic (4.10e-1)" "unprognostic (5.08e-2)" "unprognostic (1.96e-3)" "unprognostic (1.34e-1)" "unprognostic (1.53e-1)" "unprognostic (7.00e-3)" "unprognostic (1.36e-2)" "unprognostic (1.45e-2)" "unprognostic (4.26e-2)" "unprognostic (3.70e-2)" "unprognostic (9.06e-3)" "potential prognostic unfavorable (1.84e-4)" "unprognostic (1.22e-1)" "unprognostic (4.34e-1)" "unprognostic (3.34e-3)" "unprognostic (5.02e-1)" "unprognostic (2.91e-1)" "unprognostic (4.64e-3)" "unprognostic (1.24e-1)" "unprognostic (1.80e-1)" "unprognostic (1.16e-1)" "unprognostic (3.77e-3)" "unprognostic (1.28e-1)" TYW1B "LINC00069, MGC87315, NCRNA00069, RSAFD2" ENSG00000277149 "TRNA-yW synthesizing protein 1 homolog B" Q6NUM6 7 72558744-72828200 "Enzymes, Predicted membrane proteins" "tRNA processing" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.3" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 271.7" "Cell type enhanced" "Detected in many" "Ciliated cells: 271.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013568, HPA014118, HPA043136, HPA047029, HPA047052, HPA052097" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 2 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA013568: , HPA014118: , HPA043136: , HPA047029: , HPA047052: , HPA052097: " "unprognostic (1.79e-1)" "unprognostic (3.81e-1)" "unprognostic (1.87e-1)" "unprognostic (3.11e-1)" "unprognostic (7.52e-2)" "unprognostic (3.58e-1)" "unprognostic (1.30e-1)" "unprognostic (8.99e-3)" "unprognostic (5.27e-2)" "unprognostic (1.75e-1)" "unprognostic (3.88e-2)" "unprognostic (9.89e-2)" "unprognostic (8.06e-2)" "unprognostic (1.12e-1)" "unprognostic (3.19e-1)" "unprognostic (4.70e-3)" "unprognostic (1.88e-2)" "unprognostic (3.09e-1)" "unprognostic (1.85e-2)" "unprognostic (1.74e-1)" "unprognostic (3.82e-1)" "potential prognostic favorable (6.67e-4)" "unprognostic (8.10e-2)" "unprognostic (1.36e-1)" "unprognostic (7.70e-2)" "unprognostic (2.96e-1)" "unprognostic (1.89e-1)" "unprognostic (7.13e-3)" TYW3 "C1orf171, FLJ40918" ENSG00000162623 "TRNA-yW synthesizing protein 3 homolog" Q6IPR3 1 74733152-74766678 "Enzymes, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA029641 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 14 Cytosol "Plasma membrane" "HPA029641: " "unprognostic (6.27e-2)" "unprognostic (6.71e-2)" "unprognostic (1.23e-1)" "unprognostic (1.30e-1)" "unprognostic (8.02e-2)" "unprognostic (8.30e-2)" "unprognostic (1.08e-1)" "unprognostic (1.21e-2)" "unprognostic (1.86e-2)" "unprognostic (1.71e-2)" "potential prognostic favorable (3.65e-7)" "unprognostic (1.90e-3)" "potential prognostic unfavorable (4.34e-4)" "validated prognostic unfavorable (3.24e-9)" "validated prognostic unfavorable (7.25e-4)" "unprognostic (1.85e-2)" "unprognostic (1.94e-1)" "unprognostic (1.08e-1)" "unprognostic (1.20e-2)" "unprognostic (2.83e-1)" "unprognostic (1.18e-2)" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (1.94e-1)" "unprognostic (3.24e-2)" "unprognostic (1.93e-2)" "unprognostic (1.98e-1)" "unprognostic (1.80e-1)" "unprognostic (1.64e-1)" "unprognostic (4.54e-2)" "unprognostic (2.67e-1)" U2SURP "fSAPa, SR140" ENSG00000163714 "U2 snRNP associated SURP domain containing" O15042 3 142964497-143060725 "Essential proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 37417603.4" "Tissue enhanced" "Detected in many" "kidney: 13172650.9" "HPA037545, HPA037546, HPA061407" Enhanced Supported Nucleoplasm NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 17: Non-specific - RNA processing" 77 Nucleoplasm "HPA037545: , HPA037546: , HPA061407: " "unprognostic (8.74e-2)" "unprognostic (5.62e-2)" "unprognostic (6.11e-2)" "unprognostic (1.30e-1)" "unprognostic (5.54e-2)" "unprognostic (2.36e-1)" "unprognostic (5.66e-2)" "unprognostic (5.54e-2)" "unprognostic (1.32e-2)" "unprognostic (1.37e-2)" "unprognostic (2.68e-1)" "unprognostic (4.62e-2)" "potential prognostic unfavorable (8.51e-5)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (4.28e-4)" "unprognostic (4.78e-3)" "unprognostic (1.30e-1)" "unprognostic (1.20e-1)" "unprognostic (3.41e-1)" "unprognostic (1.98e-1)" "potential prognostic unfavorable (7.13e-4)" "unprognostic (1.86e-3)" "unprognostic (2.88e-3)" "unprognostic (1.27e-1)" "unprognostic (2.58e-2)" "unprognostic (1.73e-2)" "unprognostic (1.01e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (2.63e-2)" UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561722-162601240 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 93.9" "Cell type enhanced" "Detected in many" "Epicardial cells: 307.0;Fibroblasts: 395.8;Late primary spermatocytes: 314.1;Pancreatic acinar cells: 301.9;Salivary acinar cells: 302.9" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in all" 4 "fibroblast: 81.3;vascular associated smooth muscle cell: 178.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 9025989.3;Pancreas epithelial cells: 11706915.9" "Low tissue specificity" "Detected in many" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No Yes 34000 "Cluster 3: Non-specific - Nuclear processes" "Cluster 57: Testis - Spermatogenesis" "Cluster 1: Neurons - Mixed function" "Cluster 72: Neuronal - Signal transduction" "Cluster 103: Non-specific - Basic cellular processes" 1 "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: " "unprognostic (2.14e-1)" "unprognostic (9.26e-2)" "unprognostic (9.61e-2)" "unprognostic (4.05e-2)" "unprognostic (3.30e-2)" "unprognostic (1.18e-1)" "unprognostic (1.11e-2)" "unprognostic (1.01e-1)" "unprognostic (1.23e-2)" "unprognostic (6.75e-2)" "unprognostic (8.74e-3)" "unprognostic (1.11e-1)" "potential prognostic unfavorable (2.33e-4)" "unprognostic (1.90e-2)" "unprognostic (2.86e-2)" "potential prognostic unfavorable (9.39e-4)" "unprognostic (1.09e-3)" "unprognostic (7.11e-2)" "unprognostic (1.58e-1)" "unprognostic (6.79e-2)" "unprognostic (3.63e-2)" "unprognostic (1.75e-2)" "unprognostic (3.96e-2)" "unprognostic (1.81e-1)" "unprognostic (2.11e-1)" "potential prognostic unfavorable (1.78e-4)" "unprognostic (1.20e-1)" "unprognostic (1.78e-1)" "unprognostic (4.32e-2)" "unprognostic (2.93e-1)" "unprognostic (9.42e-2)" UAP1L1 ENSG00000197355 "UDP-N-acetylglucosamine pyrophosphorylase 1 like 1" Q3KQV9 9 137077517-137084539 "Metabolic proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 25.0;Choroid plexus epithelial cells: 19.4;Hofbauer cells: 31.8;Oligodendrocytes: 23.2;Retinal ganglion cells: 19.3;Retinal pigment epithelial cells: 21.3" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 31.8" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 33.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 17862988.3" "Low tissue specificity" "Detected in many" HPA044356 Approved Approved "Intermediate filaments,Cytosol" No No "Cluster 13: Non-specific - Mitochondria" "Cluster 5: Spleen - Immune response" "Cluster 11: White matter - Signal transduction" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 1 "Intermediate filaments" Cytosol "HPA044356: " "unprognostic (1.40e-1)" "unprognostic (6.94e-3)" "unprognostic (1.41e-1)" "unprognostic (1.33e-1)" "unprognostic (1.92e-2)" "unprognostic (2.42e-1)" "unprognostic (1.15e-2)" "unprognostic (9.87e-2)" "unprognostic (1.74e-1)" "unprognostic (7.89e-2)" "unprognostic (5.51e-2)" "unprognostic (2.15e-1)" "unprognostic (2.45e-1)" "potential prognostic unfavorable (4.59e-6)" "unprognostic (3.10e-1)" "unprognostic (5.52e-2)" "unprognostic (5.62e-2)" "unprognostic (2.37e-1)" "unprognostic (1.89e-2)" "unprognostic (9.84e-2)" "unprognostic (3.42e-1)" "unprognostic (1.35e-3)" "unprognostic (6.57e-3)" "unprognostic (2.07e-1)" "unprognostic (1.58e-1)" "unprognostic (9.32e-2)" "unprognostic (8.01e-2)" "unprognostic (5.50e-2)" "unprognostic (8.03e-2)" "unprognostic (3.47e-2)" "unprognostic (1.62e-2)" UBA1 "A1S9T, CFAP124, GXP1, POC20, UBE1, UBE1X" ENSG00000130985 "Ubiquitin like modifier activating enzyme 1" P22314 X 47190861-47215128 "Cancer-related genes, Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Ligase "Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 225.2" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA000289, HPA001506, CAB019435, CAB073410" Approved Supported Nucleoplasm,Cytosol NA NA 16000000 "Cluster 37: Monocytes & Neutrophils - Innate immune response" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 36: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 95 Nucleoplasm Cytosol "CAB019435: , CAB073410: , HPA000289: , HPA001506: " "unprognostic (1.40e-1)" "unprognostic (4.36e-3)" "unprognostic (3.50e-1)" "unprognostic (1.37e-2)" "unprognostic (1.56e-1)" "unprognostic (2.20e-2)" "unprognostic (1.39e-1)" "unprognostic (1.51e-1)" "unprognostic (1.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.12e-3)" "unprognostic (1.11e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (1.05e-2)" "unprognostic (2.48e-3)" "unprognostic (3.00e-3)" "unprognostic (2.18e-1)" "unprognostic (5.43e-2)" "unprognostic (1.99e-1)" "unprognostic (3.32e-1)" "potential prognostic unfavorable (6.10e-4)" "unprognostic (3.88e-1)" "unprognostic (4.68e-2)" "unprognostic (4.49e-1)" "unprognostic (9.25e-2)" "unprognostic (2.65e-1)" "unprognostic (2.00e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (2.54e-1)" UBA3 "hUba3, NAE2, UBE1C" ENSG00000144744 "Ubiquitin like modifier activating enzyme 3" Q8TBC4 3 69054730-69080408 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA034873, HPA034874, HPA065335" Supported Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA 21000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 11: White matter - Signal transduction" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 18 "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA034873: , HPA034874: , HPA065335: " "unprognostic (2.44e-3)" "unprognostic (2.00e-1)" "unprognostic (1.98e-1)" "unprognostic (2.63e-1)" "unprognostic (1.25e-1)" "unprognostic (1.74e-2)" "unprognostic (9.08e-2)" "unprognostic (1.52e-1)" "unprognostic (1.46e-1)" "unprognostic (1.93e-2)" "unprognostic (1.49e-1)" "unprognostic (1.29e-1)" "unprognostic (4.44e-3)" "unprognostic (9.73e-3)" "unprognostic (4.37e-2)" "unprognostic (1.20e-1)" "unprognostic (1.47e-2)" "unprognostic (1.96e-2)" "unprognostic (1.11e-1)" "unprognostic (4.13e-3)" "unprognostic (3.21e-2)" "unprognostic (2.60e-2)" "unprognostic (2.91e-2)" "unprognostic (3.45e-2)" "potential prognostic favorable (8.30e-4)" "unprognostic (7.53e-2)" "unprognostic (1.14e-1)" "unprognostic (3.60e-3)" "unprognostic (3.60e-2)" "unprognostic (2.87e-1)" "unprognostic (1.03e-1)" UBASH3A "CLIP4, STS-2, TULA" ENSG00000160185 "Ubiquitin associated and SH3 domain containing A" P57075 21 42403447-42447684 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "lymphoid tissue: 17.6" "Cell type enhanced" "Detected in some" "Endometrial secretory cells: 4.5;Erythrocyte progenitors: 6.6;Innate lymphoid cells: 11.0;Megakaryocyte-Erythroid progenitors: 8.9;Megakaryocytes: 18.5;NK-cells: 9.3;T-cells: 47.5;Thymocytes: 5.1" "Cell type enhanced" "Detected in some" "Innate lymphoid cells: 11.0;Megakaryocytes: 18.5;T-cells: 47.5" "Cell type enriched" "Detected in single" 546 "leukocyte: 54.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "gdT-cell: 12.9;MAIT T-cell: 23.0;memory CD4 T-cell: 28.3;memory CD8 T-cell: 24.8;naive CD4 T-cell: 32.3;naive CD8 T-cell: 24.1;T-reg: 28.0" "Lineage enriched" "Detected in many" 12 "T-cells: 32.3" "Cancer enriched" "Detected in some" 5 "Leukemia: 9.2" "Adipose subcutaneous - T-cells, Adipose visceral - T-cells, Adrenal gland - T-cells, Breast - T-cells, Colon - T-cells, Kidney - T-cells, Liver - T-cells, Lung - T-cells, Minor Salivary Gland - T-cells, Pancreas - T-cells, Pituitary gland - T-cells, Prostate - T-cells, Spleen - T-cells, Stomach - T-cells, Thyroid gland - T-cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 3172630.4" "Tissue enriched" "Detected in some" "bone marrow: 2956428.1" HPA049738 Supported "Nucleoplasm,Nuclear speckles,Cytosol" NA NA "Cluster 39: T-cells - T-cell receptor" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 59: Leukemia - T-cell receptor" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Nucleoplasm "Nuclear speckles, Cytosol" "HPA049738: " "unprognostic (1.89e-3)" "unprognostic (8.06e-3)" "unprognostic (2.61e-3)" "unprognostic (6.55e-2)" "unprognostic (3.13e-1)" "unprognostic (7.52e-2)" "unprognostic (1.19e-2)" "potential prognostic favorable (4.64e-4)" "unprognostic (1.43e-1)" "unprognostic (1.02e-1)" "unprognostic (8.49e-3)" "unprognostic (2.48e-1)" "unprognostic (1.21e-1)" "unprognostic (2.18e-1)" "unprognostic (1.57e-1)" UBASH3B "KIAA1959, STS-1, TULA-2, TULA2" ENSG00000154127 "Ubiquitin associated and SH3 domain containing B" Q8TF42 11 122655722-122814473 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 21.2;lymphoid tissue: 14.7;placenta: 12.9" "Cell type enhanced" "Detected in many" "cDC: 260.6;Cytotrophoblasts: 268.7;Extravillous trophoblasts: 340.5;Hematopoietic stem cells: 280.5;Innate lymphoid cells: 264.2;Megakaryocyte progenitors: 256.8;Megakaryocytes: 247.3;monocytes: 245.2;Neutrophils: 321.3;Schwann cells: 239.4;Syncytiotrophoblasts: 303.9;Thymocytes: 816.5" "Cell type enhanced" "Detected in all" "T-cells: 816.5" "Cell type enhanced" "Detected in all" "upper rhombic lip: 448.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (granular)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes and Neuropil: 1002154.9;Macrophages: 1473881.0" "Group enriched" "Detected in some" "lung: 1196265.6;lymphoid tissue: 4510161.4" "HPA038605, HPA038606, HPA038607" Approved Approved "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 150000 "Cluster 25: Non-specific - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 92: NK-cells & T-cells - Adaptive immunity: Cytotoxicity" 51 Cytosol "Nucleoplasm, Nuclear bodies" "HPA038605: , HPA038606: , HPA038607: " "unprognostic (6.96e-3)" "unprognostic (5.81e-2)" "unprognostic (1.16e-1)" "unprognostic (5.74e-2)" "unprognostic (5.06e-1)" "unprognostic (1.18e-1)" "unprognostic (3.82e-1)" "unprognostic (2.99e-1)" "unprognostic (1.11e-1)" "unprognostic (2.44e-2)" "unprognostic (2.75e-1)" "unprognostic (2.28e-1)" "unprognostic (2.80e-1)" "unprognostic (1.08e-1)" "unprognostic (2.59e-2)" "unprognostic (2.17e-3)" "unprognostic (1.48e-2)" "unprognostic (3.31e-1)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (1.44e-4)" "unprognostic (7.87e-2)" "unprognostic (2.18e-2)" "unprognostic (6.33e-2)" "unprognostic (9.98e-2)" "unprognostic (1.46e-1)" "unprognostic (1.54e-2)" "unprognostic (1.80e-3)" "unprognostic (4.42e-1)" UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 74.0;lymphoid tissue: 105.6" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 134.4;Enteric transient amplifying cells: 232.5;Esophageal basal cells: 179.4;Extravillous trophoblasts: 511.3;Gastric progenitor cells: 528.0;Hofbauer cells: 143.6;Megakaryocyte progenitors: 337.6;Megakaryocytes: 680.0;Migrating cytotrophoblasts: 260.1;Monocyte progenitors: 158.8;Oocytes: 497.3" "Cell type enhanced" "Detected in many" "Megakaryocytes: 680.0;Oocytes: 497.3;Proliferating cells: 528.0;Trophoblast cells: 511.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Mitotic cells (Heart), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Thyroid gland - Mitotic cells (Thyroid)" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.5" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Granulosa cells: 3154285.4" "Group enriched" "Detected in some" 1878 "bone marrow: 290764.0;intestine: 84782.8" "CAB011464, HPA034569, CAB035990, HPA054975, CAB080407" Approved Supported "Plasma membrane,Cytosol" Yes Yes "Cluster 16: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 48: Non-specific - Mixed function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 27: Non-specific - Cell proliferation" 15 "Plasma membrane, Cytosol" "CAB011464: , CAB035990: , CAB080407: , HPA034569: , HPA054975: " "unprognostic (3.63e-2)" "unprognostic (1.90e-2)" "unprognostic (1.01e-1)" "unprognostic (1.32e-1)" "unprognostic (2.25e-1)" "unprognostic (3.33e-2)" "unprognostic (2.60e-1)" "unprognostic (1.29e-3)" "unprognostic (1.07e-1)" "potential prognostic unfavorable (5.60e-6)" "validated prognostic unfavorable (1.67e-13)" "validated prognostic unfavorable (2.92e-7)" "potential prognostic unfavorable (2.33e-12)" "validated prognostic unfavorable (5.02e-6)" "validated prognostic unfavorable (1.88e-8)" "validated prognostic unfavorable (4.61e-5)" "validated prognostic unfavorable (1.59e-4)" "unprognostic (4.54e-2)" "unprognostic (3.98e-1)" "unprognostic (1.64e-1)" "unprognostic (6.45e-3)" "validated prognostic unfavorable (3.28e-4)" "validated prognostic unfavorable (9.97e-4)" "unprognostic (3.79e-2)" "unprognostic (2.32e-1)" "unprognostic (6.43e-3)" "unprognostic (2.02e-1)" "unprognostic (1.83e-1)" "unprognostic (1.90e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-3)" UBE2E1 UbcH6 ENSG00000170142 "Ubiquitin conjugating enzyme E2 E1" P51965 3 23805955-23891640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030445, CAB073413, CAB080048" Approved Supported Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 55: Non-specific - Transcription" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 68 Nucleoplasm "CAB073413: , CAB080048: , HPA030445: " "unprognostic (2.79e-1)" "unprognostic (3.53e-2)" "unprognostic (1.15e-1)" "unprognostic (3.55e-2)" "unprognostic (1.27e-1)" "unprognostic (2.32e-1)" "unprognostic (1.71e-2)" "unprognostic (8.07e-2)" "unprognostic (6.96e-2)" "potential prognostic unfavorable (1.28e-4)" "potential prognostic favorable (3.71e-5)" "unprognostic (2.23e-1)" "unprognostic (5.36e-2)" "potential prognostic unfavorable (1.17e-11)" "unprognostic (3.25e-3)" "unprognostic (1.60e-2)" "potential prognostic unfavorable (5.44e-4)" "unprognostic (1.43e-1)" "unprognostic (1.13e-1)" "unprognostic (1.39e-2)" "unprognostic (4.44e-2)" "unprognostic (2.07e-2)" "unprognostic (1.12e-3)" "unprognostic (6.39e-2)" "unprognostic (8.01e-2)" "unprognostic (1.65e-1)" "unprognostic (1.17e-1)" "unprognostic (1.85e-1)" "unprognostic (1.08e-1)" "unprognostic (1.68e-1)" "unprognostic (4.61e-2)" UBE2E2 "FLJ25157, UbcH8" ENSG00000182247 "Ubiquitin conjugating enzyme E2 E2" Q96LR5 3 23203020-23591794 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 1164.6;Microglia: 1417.6;Myonuclei: 1643.7" "Cell type enhanced" "Detected in all" "Myocytes: 1643.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 41.8;intermediate monocyte: 50.5;memory B-cell: 35.3;myeloid DC: 57.7;naive B-cell: 40.3;non-classical monocyte: 55.0;plasmacytoid DC: 74.3" "Group enriched" "Detected in all" 6 "B-cells: 40.3;dendritic cells: 74.3;monocytes: 55.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Neurons: 32805.7;Oocytes: 88936.0" "Tissue enriched" "Detected in some" "lymphoid tissue: 239522.8" "HPA003303, HPA028872, HPA030445, CAB073417" Approved Approved Nucleoplasm No No "Cluster 23: B-cells - Immunoglobulins" "Cluster 74: Non-specific - Signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 74: Microglia - Neuroimmunity & neuroinflammation" 61 Nucleoplasm "CAB073417: , HPA003303: , HPA028872: , HPA030445: " "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" "unprognostic (6.30e-3)" "unprognostic (4.41e-2)" "unprognostic (7.17e-2)" "unprognostic (2.54e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (9.07e-6)" "unprognostic (1.33e-2)" "unprognostic (1.33e-1)" "potential prognostic favorable (4.20e-5)" "unprognostic (2.00e-1)" "unprognostic (2.64e-2)" "unprognostic (1.92e-2)" "unprognostic (1.73e-2)" "unprognostic (1.60e-1)" "unprognostic (1.31e-2)" "potential prognostic unfavorable (8.46e-4)" "unprognostic (1.33e-2)" "unprognostic (1.71e-1)" "unprognostic (2.73e-2)" "unprognostic (8.36e-2)" "unprognostic (2.63e-3)" "unprognostic (2.73e-1)" "unprognostic (3.10e-2)" "unprognostic (1.63e-1)" "unprognostic (7.16e-2)" "unprognostic (4.85e-2)" "unprognostic (2.60e-1)" "unprognostic (1.73e-1)" "unprognostic (3.10e-1)" UBE2M "hUbc12, UBC12" ENSG00000130725 "Ubiquitin conjugating enzyme E2 M" P61081 19 58555712-58558954 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Prostate - Smooth muscle cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004993, HPA054551, HPA057800" Approved Enhanced "Nucleoplasm,Nucleoli,Nuclear bodies,Cytosol" Yes No 39000 "Cluster 7: Non-specific - Innate immune response" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" 83 Nucleoplasm "Nucleoli, Nuclear bodies, Cytosol" "CAB004993: , HPA054551: , HPA057800: " "unprognostic (3.18e-2)" "unprognostic (1.67e-1)" "unprognostic (7.91e-2)" "unprognostic (2.07e-2)" "unprognostic (7.58e-2)" "unprognostic (1.54e-1)" "unprognostic (1.60e-1)" "unprognostic (1.78e-2)" "unprognostic (2.41e-3)" "unprognostic (3.70e-2)" "potential prognostic favorable (4.22e-4)" "unprognostic (6.25e-2)" "unprognostic (7.17e-3)" "validated prognostic unfavorable (1.82e-5)" "validated prognostic unfavorable (6.79e-7)" "unprognostic (1.99e-3)" "unprognostic (1.13e-1)" "unprognostic (3.90e-3)" "unprognostic (3.51e-2)" "unprognostic (8.50e-2)" "unprognostic (3.36e-2)" "unprognostic (5.04e-3)" "unprognostic (2.61e-1)" "unprognostic (1.32e-1)" "unprognostic (3.33e-1)" "unprognostic (4.69e-2)" "unprognostic (2.54e-1)" "unprognostic (1.88e-1)" "unprognostic (1.83e-1)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" UBE2O E2-230K ENSG00000175931 "Ubiquitin conjugating enzyme E2 O" Q9C0C9 17 76389456-76453152 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Retinal ganglion cells: 193.1;Retinal horizontal cells: 164.3" "Cell type enhanced" "Detected in all" "Neuronal cells: 193.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Skeletal myofibers: 34182786.3" "Low tissue specificity" "Detected in all" HPA023605 Uncertain Supported "Nucleoplasm,Nuclear bodies" No No 450000 "Cluster 18: Non-specific - Translation" "Cluster 24: Non-specific - Transcription" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 109: Neurons - Neuronal signaling" 144 "Nuclear bodies" Nucleoplasm "HPA023605: " "unprognostic (3.85e-1)" "unprognostic (7.96e-2)" "unprognostic (1.55e-1)" "unprognostic (1.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.70e-3)" "unprognostic (1.97e-1)" "unprognostic (4.24e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-2)" "unprognostic (1.74e-1)" "unprognostic (2.20e-1)" "unprognostic (2.35e-2)" "validated prognostic unfavorable (1.00e-6)" "validated prognostic unfavorable (4.13e-4)" "unprognostic (1.19e-1)" "potential prognostic unfavorable (9.15e-5)" "unprognostic (1.08e-1)" "unprognostic (4.89e-3)" "unprognostic (5.75e-2)" "unprognostic (6.02e-2)" "unprognostic (4.98e-3)" "unprognostic (4.36e-2)" "unprognostic (9.81e-3)" "unprognostic (4.53e-2)" "unprognostic (1.33e-2)" "unprognostic (1.61e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-1)" "unprognostic (7.60e-2)" "unprognostic (5.27e-2)" UBE2Q1 "NICE-5, PRO3094, UBE2Q" ENSG00000160714 "Ubiquitin conjugating enzyme E2 Q1" Q7Z7E8 1 154548577-154559028 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 2462959.1" HPA063368 Approved Approved Nucleoplasm,Centrosome,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 1: Choroid plexus - Transmembrane transport" "Cluster 1: Neurons - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 5 Nucleoplasm "Centrosome, Cytosol" "HPA063368: " "unprognostic (8.51e-2)" "unprognostic (1.13e-2)" "unprognostic (3.90e-1)" "unprognostic (9.41e-3)" "unprognostic (1.41e-1)" "unprognostic (1.98e-3)" "unprognostic (2.09e-1)" "unprognostic (5.52e-2)" "unprognostic (1.53e-2)" "unprognostic (2.13e-2)" "unprognostic (1.08e-1)" "unprognostic (4.86e-3)" "unprognostic (3.11e-2)" "unprognostic (1.50e-3)" "unprognostic (2.26e-1)" "unprognostic (2.74e-2)" "unprognostic (1.04e-1)" "unprognostic (1.17e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (2.47e-2)" "unprognostic (1.46e-1)" "unprognostic (5.37e-2)" "unprognostic (2.21e-1)" "unprognostic (6.86e-3)" "unprognostic (4.59e-3)" "unprognostic (3.32e-1)" "unprognostic (3.55e-1)" "unprognostic (1.26e-1)" "unprognostic (2.69e-2)" "unprognostic (1.96e-2)" UBE2R2 "CDC34B, FLJ20419, MGC10481, UBC3B" ENSG00000107341 "Ubiquitin conjugating enzyme E2 R2" Q712K3 9 33817160-33920399 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 1721.8" "Cell type enhanced" "Detected in all" "Neutrophils: 1721.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Capillaries: 34810842.6;Cardiomyocytes: 82154645.6;Skeletal myofibers: 120075066.1" "Low tissue specificity" "Detected in all" "HPA061000, HPA074334" Approved Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 28: Neutrophils - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 24: Neutrophils - Innate immunity signal integration" 13 "Nucleoplasm, Nucleoli" Cytosol "HPA061000: , HPA074334: " "unprognostic (1.58e-2)" "unprognostic (1.72e-1)" "unprognostic (4.00e-3)" "unprognostic (8.98e-2)" "unprognostic (2.02e-1)" "potential prognostic unfavorable (7.12e-4)" "unprognostic (1.31e-1)" "unprognostic (3.58e-2)" "unprognostic (7.47e-2)" "unprognostic (6.27e-2)" "potential prognostic favorable (1.54e-6)" "unprognostic (7.48e-3)" "unprognostic (2.04e-1)" "validated prognostic unfavorable (2.61e-4)" "validated prognostic unfavorable (3.00e-4)" "unprognostic (1.02e-3)" "potential prognostic unfavorable (4.65e-4)" "unprognostic (8.45e-2)" "unprognostic (7.86e-2)" "unprognostic (7.39e-2)" "unprognostic (3.60e-2)" "potential prognostic unfavorable (6.60e-4)" "unprognostic (3.40e-1)" "unprognostic (2.75e-1)" "unprognostic (6.59e-2)" "unprognostic (7.82e-2)" "unprognostic (1.59e-1)" "unprognostic (4.67e-2)" "unprognostic (1.88e-1)" "unprognostic (5.69e-2)" "unprognostic (4.81e-2)" UBE2W "FLJ11011, UBC-16" ENSG00000104343 "Ubiquitin conjugating enzyme E2 W" Q96B02 8 73780097-73878910 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 62.7;Bergmann glia: 93.2;Brain excitatory neurons: 129.1;Brain inhibitory neurons: 105.1;Choroid plexus epithelial cells: 150.9;Early spermatids: 58.8;Ependymal cells: 82.4;Late spermatids: 49.2;Microglia: 332.0;Oligodendrocyte progenitor cells: 94.7;Oligodendrocytes: 90.1;Other brain neurons: 104.5" "Cell type enhanced" "Detected in some" "Ciliated cells: 150.9;Glial cells: 332.0;Neuronal cells: 129.1;Spermatogenic cell types: 58.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045161, HPA073181" Uncertain Approved Nucleoli NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 76: Non-specific - Metabolism" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 42 Nucleoli "HPA045161: , HPA073181: " "unprognostic (4.74e-2)" "unprognostic (4.13e-2)" "unprognostic (1.08e-1)" "unprognostic (4.93e-2)" "unprognostic (1.16e-1)" "unprognostic (1.41e-1)" "unprognostic (1.48e-2)" "unprognostic (3.31e-2)" "unprognostic (1.02e-1)" "unprognostic (1.95e-3)" "potential prognostic favorable (2.52e-6)" "unprognostic (1.01e-1)" "unprognostic (8.36e-2)" "unprognostic (3.35e-3)" "unprognostic (6.86e-2)" "unprognostic (1.07e-2)" "unprognostic (2.72e-2)" "unprognostic (1.37e-1)" "unprognostic (6.81e-2)" "unprognostic (2.73e-2)" "unprognostic (1.50e-3)" "unprognostic (2.12e-2)" "unprognostic (3.29e-3)" "unprognostic (2.65e-1)" "unprognostic (3.51e-2)" "unprognostic (5.38e-2)" "unprognostic (2.48e-1)" "unprognostic (2.28e-1)" "unprognostic (2.84e-1)" "unprognostic (1.32e-1)" "unprognostic (6.02e-2)" UBE2Z "FLJ13855, USE1" ENSG00000159202 "Ubiquitin conjugating enzyme E2 Z" Q9H832 17 48908407-48929056 "Enzymes, Essential proteins, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipose progenitor cells, Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" HPA007922 Approved Supported Nucleoplasm,Cytosol NA NA 24000 "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 17: Non-specific - RNA processing" 16 "Nucleoplasm, Cytosol" "HPA007922: " "unprognostic (8.08e-2)" "unprognostic (3.97e-1)" "unprognostic (3.04e-1)" "unprognostic (3.04e-2)" "unprognostic (4.19e-2)" "potential prognostic unfavorable (3.14e-4)" "unprognostic (4.77e-2)" "unprognostic (2.73e-1)" "unprognostic (1.45e-1)" "potential prognostic unfavorable (2.76e-4)" "unprognostic (3.63e-2)" "unprognostic (2.43e-1)" "unprognostic (1.46e-1)" "validated prognostic unfavorable (3.62e-4)" "validated prognostic unfavorable (5.41e-4)" "potential prognostic unfavorable (8.17e-5)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (5.51e-2)" "unprognostic (4.53e-2)" "unprognostic (2.47e-3)" "unprognostic (8.95e-2)" "unprognostic (1.38e-3)" "unprognostic (3.63e-2)" "unprognostic (9.31e-2)" "unprognostic (4.46e-2)" "unprognostic (1.79e-1)" "unprognostic (2.31e-1)" "unprognostic (1.06e-1)" "unprognostic (7.74e-3)" "unprognostic (7.27e-2)" UBFD1 "FLJ38870, FLJ42145, UBPH" ENSG00000103353 "Ubiquitin family domain containing 1" O14562 16 23557721-23574389 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 74.7" "Cell type enhanced" "Detected in many" "Early spermatids: 74.2;Late spermatids: 110.8;Myonuclei: 69.2" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 110.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 2609865.3" "Tissue enhanced" "Detected in all" "blood vessel: 31211433.7" HPA051746 Approved Nucleoplasm,Nucleoli,Midbody Yes NA "Cluster 30: Non-specific - DNA binding" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 1: Neurons - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 2 Nucleoplasm "Nucleoli, Midbody" "HPA051746: " "unprognostic (1.42e-1)" "unprognostic (2.84e-2)" "unprognostic (4.07e-2)" "unprognostic (1.93e-1)" "unprognostic (1.25e-1)" "unprognostic (2.29e-1)" "unprognostic (7.10e-2)" "unprognostic (2.47e-2)" "unprognostic (2.17e-1)" "unprognostic (1.12e-1)" "unprognostic (3.69e-3)" "unprognostic (1.01e-1)" "unprognostic (4.80e-3)" "unprognostic (2.55e-3)" "unprognostic (4.91e-2)" "unprognostic (2.09e-2)" "unprognostic (2.03e-2)" "unprognostic (1.60e-1)" "unprognostic (3.18e-1)" "unprognostic (2.17e-1)" "unprognostic (7.04e-2)" "unprognostic (4.13e-2)" "unprognostic (1.39e-3)" "unprognostic (2.57e-2)" "unprognostic (7.51e-3)" "unprognostic (1.43e-1)" "unprognostic (3.36e-1)" "unprognostic (6.24e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" "unprognostic (1.14e-1)" UBLCP1 "CPUB1, MGC10067" ENSG00000164332 "Ubiquitin like domain containing CTD phosphatase 1" Q8WVY7 5 159263290-159286036 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 149.2" "Cell type enhanced" "Detected in many" "Neutrophils: 149.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA039615 Approved Supported "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA 5300 "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 14: Neurons - Synaptic function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 36 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA039615: " "unprognostic (1.33e-1)" "unprognostic (9.18e-2)" "unprognostic (8.09e-2)" "unprognostic (1.49e-1)" "unprognostic (7.46e-2)" "unprognostic (2.64e-1)" "unprognostic (9.99e-2)" "potential prognostic unfavorable (1.97e-4)" "unprognostic (7.92e-2)" "unprognostic (4.73e-2)" "potential prognostic favorable (1.16e-6)" "unprognostic (1.05e-1)" "unprognostic (9.31e-2)" "unprognostic (3.25e-2)" "unprognostic (6.40e-2)" "unprognostic (7.88e-3)" "unprognostic (1.58e-1)" "unprognostic (5.12e-2)" "unprognostic (2.63e-1)" "unprognostic (3.74e-2)" "unprognostic (8.75e-3)" "unprognostic (9.80e-3)" "unprognostic (1.24e-2)" "unprognostic (7.03e-2)" "unprognostic (8.16e-3)" "unprognostic (7.02e-2)" "unprognostic (6.58e-2)" "unprognostic (4.48e-2)" "unprognostic (1.50e-1)" "unprognostic (2.67e-3)" "unprognostic (2.68e-1)" UBXN2B p37 ENSG00000215114 "UBX domain protein 2B" Q14CS0 8 58411359-58451501 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 6 "Neutrophils: 908.1" "Cell type enriched" "Detected in many" 9 "Neutrophils: 908.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 42.9" "Group enriched" "Detected in all" 5 "granulocytes: 42.9;monocytes: 13.0" "Low cancer specificity" "Detected in all" "Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1178392.2" "Group enriched" "Detected in some" "bone marrow: 1007348.4;intestine: 437991.9" HPA045278 Uncertain Approved Nucleoplasm No No "Cluster 28: Neutrophils - Unknown function" "Cluster 36: Brain & Liver - Signaling" "Cluster 31: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 23 Nucleoplasm "HPA045278: " "unprognostic (7.27e-2)" "unprognostic (3.53e-3)" "unprognostic (9.66e-2)" "unprognostic (1.73e-1)" "unprognostic (7.80e-2)" "unprognostic (3.30e-1)" "unprognostic (3.26e-2)" "unprognostic (1.17e-1)" "unprognostic (1.34e-1)" "unprognostic (1.83e-2)" "potential prognostic favorable (1.24e-5)" "unprognostic (7.18e-2)" "unprognostic (9.17e-2)" "unprognostic (3.45e-1)" "unprognostic (1.29e-1)" "unprognostic (2.43e-1)" "unprognostic (1.71e-2)" "unprognostic (6.51e-2)" "unprognostic (1.37e-1)" "unprognostic (1.22e-1)" "unprognostic (4.88e-2)" "unprognostic (2.99e-2)" "unprognostic (3.23e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.19e-2)" "unprognostic (4.23e-1)" "unprognostic (4.71e-2)" "unprognostic (2.79e-1)" "unprognostic (9.96e-2)" "unprognostic (5.56e-1)" UCHL1 "PARK5, PGP9.5, Uch-L1, UCHL-1" ENSG00000154277 "Ubiquitin C-terminal hydrolase L1" P09936 4 41256413-41268455 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 1037.7;pituitary gland: 337.4" "Cell type enriched" "Detected in many" 4 "Oocytes: 2030.8" "Cell type enriched" "Detected in many" 4 "Oocytes: 2030.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Glioblastoma Multiforme (TCGA): 316.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Colon - Colon enteroendocrine cells, Pancreas - Alpha cells, Pancreas - Beta cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 631748728.7;Oocytes: 1719732514.8" "Tissue enriched" "Detected in all" "cerebral cortex: 2128189083.5" "CAB002580, HPA005993, CAB079024" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA 80000 "Cluster 17: B-cells - Immunoglobulins" "Cluster 78: Brain - Neuronal signaling" "Cluster 1: Neurons - Mixed function" "Cluster 7: Liver cancer - Metabolism" "Cluster 98: Neurons - Neurotransmission & signaling" 66 Cytosol Nucleoplasm "CAB002580: , CAB079024: , HPA005993: " "unprognostic (3.80e-2)" "unprognostic (6.52e-2)" "unprognostic (7.58e-2)" "unprognostic (5.74e-2)" "unprognostic (2.43e-2)" "unprognostic (3.10e-2)" "unprognostic (1.62e-1)" "unprognostic (2.34e-1)" "unprognostic (2.48e-1)" "unprognostic (4.23e-1)" "potential prognostic unfavorable (4.40e-6)" "unprognostic (3.61e-3)" "unprognostic (2.33e-2)" "potential prognostic unfavorable (1.83e-4)" "unprognostic (5.55e-2)" "unprognostic (3.55e-2)" "unprognostic (2.72e-1)" "unprognostic (2.46e-1)" "potential prognostic favorable (7.61e-4)" "unprognostic (1.44e-2)" "unprognostic (1.46e-1)" "unprognostic (2.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (3.25e-1)" "unprognostic (1.22e-1)" "unprognostic (1.04e-1)" "unprognostic (2.67e-2)" "unprognostic (2.77e-2)" "unprognostic (7.26e-3)" "unprognostic (5.19e-3)" UCHL3 ENSG00000118939 "Ubiquitin C-terminal hydrolase L3" P15374 13 75549480-75606020 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 170.6;Esophageal apical cells: 160.9;Esophageal basal cells: 133.3;Esophageal suprabasal cells: 203.6;Extravillous trophoblasts: 166.2;Late primary spermatocytes: 312.8;Syncytiotrophoblasts: 186.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 312.8;Suprabasal cells: 203.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA019678, CAB037139, CAB037208" Approved Approved "Nucleoplasm,Golgi apparatus,Cytosol" No No 670000 "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 76: Non-specific - Metabolism" "Cluster 33: Neurons - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 85: Squamous epithelial cells - Keratinization" 22 "Nucleoplasm, Cytosol" "Golgi apparatus" "CAB037139: , CAB037208: , HPA019678: " "unprognostic (1.98e-1)" "unprognostic (1.95e-1)" "unprognostic (3.03e-1)" "unprognostic (1.99e-1)" "unprognostic (8.49e-2)" "unprognostic (1.14e-1)" "unprognostic (1.67e-2)" "unprognostic (1.18e-1)" "unprognostic (5.40e-3)" "unprognostic (1.05e-1)" "potential prognostic favorable (8.44e-5)" "unprognostic (8.65e-2)" "unprognostic (4.58e-3)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (8.45e-4)" "unprognostic (5.41e-3)" "potential prognostic unfavorable (2.15e-5)" "unprognostic (2.86e-1)" "unprognostic (4.37e-2)" "unprognostic (1.88e-1)" "unprognostic (3.41e-2)" "unprognostic (1.86e-2)" "unprognostic (1.60e-1)" "unprognostic (4.84e-2)" "unprognostic (7.38e-2)" "unprognostic (1.60e-1)" "unprognostic (2.44e-2)" "unprognostic (5.04e-1)" "unprognostic (2.52e-1)" "unprognostic (2.49e-2)" "unprognostic (1.24e-1)" UCK1 "FLJ12255, URK1" ENSG00000130717 "Uridine-cytidine kinase 1" Q9HA47 9 131523801-131531264 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 50.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "kidney: 1727774.2" "HPA050969, HPA070526" Approved Approved Nucleoplasm,Nucleoli NA NA "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 24: Non-specific - Transcription" "Cluster 19: Astrocytes - Mixed function" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 7 Nucleoplasm Nucleoli "HPA050969: , HPA070526: " "unprognostic (3.06e-2)" "unprognostic (9.05e-2)" "unprognostic (4.71e-2)" "unprognostic (6.17e-2)" "unprognostic (6.25e-2)" "unprognostic (1.01e-1)" "unprognostic (1.61e-1)" "unprognostic (8.05e-3)" "unprognostic (1.46e-1)" "unprognostic (1.33e-1)" "potential prognostic favorable (5.33e-6)" "unprognostic (2.36e-3)" "unprognostic (1.10e-3)" "unprognostic (5.43e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (4.11e-1)" "unprognostic (2.08e-2)" "unprognostic (6.72e-3)" "unprognostic (8.60e-2)" "unprognostic (1.67e-1)" "unprognostic (3.73e-2)" "unprognostic (1.18e-1)" "unprognostic (2.66e-1)" "unprognostic (2.26e-1)" "unprognostic (2.80e-1)" "unprognostic (1.61e-1)" "unprognostic (2.19e-1)" "unprognostic (2.75e-2)" "unprognostic (5.58e-2)" "unprognostic (3.83e-2)" UFD1 UFD1L ENSG00000070010 "Ubiquitin recognition factor in ER associated degradation 1" Q92890 22 19449911-19479202 "Essential proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 386.3;Late spermatids: 335.7;Syncytiotrophoblasts: 221.6" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 386.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA030286, HPA030287" Approved Approved Nucleoplasm,Nucleoli,Cytosol NA NA 6300 "Cluster 42: Non-specific - Vesicular transport" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 27: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 30 "Nucleoplasm, Cytosol" Nucleoli "HPA030286: , HPA030287: " "unprognostic (1.69e-3)" "unprognostic (8.42e-3)" "unprognostic (1.24e-2)" "potential prognostic favorable (8.95e-4)" "unprognostic (6.81e-2)" "unprognostic (3.49e-1)" "unprognostic (4.93e-3)" "unprognostic (5.29e-3)" "potential prognostic unfavorable (2.39e-5)" "potential prognostic favorable (6.91e-4)" "unprognostic (4.34e-3)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (8.57e-4)" "potential prognostic unfavorable (1.20e-4)" "unprognostic (1.87e-1)" "unprognostic (2.66e-2)" "unprognostic (1.06e-2)" "unprognostic (2.30e-2)" "unprognostic (1.94e-1)" "unprognostic (3.16e-3)" "unprognostic (1.17e-2)" "unprognostic (5.90e-2)" "unprognostic (3.84e-2)" "unprognostic (1.70e-2)" "unprognostic (1.02e-1)" "unprognostic (2.35e-2)" "unprognostic (1.38e-1)" "unprognostic (2.98e-1)" "unprognostic (1.03e-1)" UGDH ENSG00000109814 "UDP-glucose 6-dehydrogenase" O60701 4 39498755-39528311 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism" "Allosteric enzyme, Oxidoreductase" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 128.7" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 439.4;Colonocytes: 642.3;Enterocytes: 401.9;Goblet cells: 300.8;Hepatocytes: 346.1;Pancreatic acinar cells: 404.0" "Cell type enhanced" "Detected in all" "Enterocytes: 642.3" "Cell type enhanced" "Detected in all" "committed oligodendrocyte precursor: 98.9;oligodendrocyte precursor cell: 96.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 737705075.8" "Group enriched" "Detected in all" "liver: 905368662.6;pancreas: 490634812.3" "CAB034444, HPA036656, HPA036657" Enhanced Approved Nucleoplasm Yes No 830000 "Cluster 41: Basophils - Unknown function" "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 7: Liver cancer - Metabolism" "Cluster 65: Non-specific - Cell growth & division" 4 Nucleoplasm "CAB034444: , HPA036656: , HPA036657: " "unprognostic (9.58e-3)" "unprognostic (1.23e-1)" "unprognostic (1.77e-2)" "unprognostic (5.64e-2)" "unprognostic (3.42e-2)" "unprognostic (7.25e-2)" "unprognostic (3.42e-1)" "unprognostic (1.13e-1)" "unprognostic (3.03e-2)" "unprognostic (1.16e-1)" "unprognostic (2.00e-3)" "unprognostic (6.12e-2)" "potential prognostic unfavorable (1.13e-5)" "unprognostic (1.43e-3)" "unprognostic (1.39e-2)" "unprognostic (5.48e-3)" "unprognostic (5.29e-3)" "unprognostic (4.71e-1)" "unprognostic (4.27e-2)" "unprognostic (4.16e-2)" "unprognostic (2.41e-1)" "unprognostic (1.24e-2)" "unprognostic (4.01e-1)" "unprognostic (5.05e-2)" "unprognostic (1.88e-1)" "unprognostic (2.72e-3)" "unprognostic (3.67e-1)" "unprognostic (2.58e-1)" "unprognostic (5.06e-2)" "unprognostic (4.43e-2)" "unprognostic (6.68e-2)" UGT3A2 ENSG00000168671 "UDP glycosyltransferase family 3 member A2" Q3SY77 5 36035021-36071358 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.1;lymphoid tissue: 13.6;skin 1: 9.7" "Cell type enhanced" "Detected in some" "Adrenal medulla cells: 10.6;Early spermatids: 3.7;Late spermatids: 14.7;Neutrophil progenitors: 2.7;Retinal ganglion cells: 3.9;Retinal pigment epithelial cells: 12.8;Sertoli cells: 5.6;Thymocytes: 7.6;Thyrotrophs: 7.3" "Cell type enhanced" "Detected in some" "Adrenal endocrine cells: 10.6;Pigment cells: 12.8;Pituitary endocrine cells: 7.3;Spermatogenic cell types: 14.7;T-cells: 7.6" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 1.7;lower rhombic lip: 2.8;thalamic excitatory: 2.2" "Cancer enhanced" "Detected in some" "Testicular Germ Cell Tumor (TCGA): 7.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Bone cancer: 178.0" "Colon - Colon enteroendocrine cells, Kidney - Proximal tubular cells, Pituitary gland - Thyrotropes" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 1085 "Proximal tubules: 108499.7" "Not detected" "Not detected" HPA059475 Uncertain Approved "Nucleoplasm,Golgi apparatus,Cytosol" Yes NA "Cluster 49: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 99: Retinal pigment epithelial cells - Retinol metabolism" Nucleoplasm "Golgi apparatus, Cytosol" "HPA059475: " "unprognostic (1.15e-2)" "unprognostic (6.56e-2)" "unprognostic (4.16e-3)" "unprognostic (1.94e-1)" "unprognostic (7.12e-3)" "unprognostic (2.06e-1)" UGT8 CGT ENSG00000174607 "UDP glycosyltransferase 8" Q16880 4 114598770-114678225 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 244.3" "Cell type enhanced" "Detected in many" "Distal convoluted tubule cells: 88.1;Loop of henle epithelial cells: 243.3;Oligodendrocyte progenitor cells: 135.4;Oligodendrocytes: 850.8;Renal collecting duct intercalated cells: 300.3;Tuft cells: 92.2" "Group enriched" "Detected in many" 5 "Ductal cells: 300.3;Glial cells: 850.8;Renal nephron cells: 243.3" "Group enriched" "Detected in many" 5 "committed oligodendrocyte precursor: 526.4;oligodendrocyte: 1203.7" "Cancer enhanced" "Detected in many" "Kidney Chromophobe (TCGA): 70.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "memory B-cell: 6.9;naive B-cell: 10.7" "Lineage enriched" "Detected in single" 13 "B-cells: 10.7" "Low cancer specificity" "Detected in many" "Colon - Colon enterocytes, Skin - Eccrine sweat gland cells, Spleen - B-cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes and Neuropil: 2095211.3;Distal tubules: 3598752.8" "Tissue enriched" "Detected in some" "cerebral cortex: 1876753.9" "HPA014405, HPA065785" Enhanced Approved Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 30: White matter - Myelination" "Cluster 11: Neuronal - Sensory perception" "Cluster 80: Oligodendrocytes - Myelination" 24 Mitochondria "HPA014405: , HPA065785: " "unprognostic (3.52e-1)" "unprognostic (2.01e-1)" "unprognostic (3.65e-1)" "unprognostic (2.91e-2)" "unprognostic (1.71e-2)" "unprognostic (1.70e-1)" "unprognostic (2.13e-1)" "potential prognostic favorable (7.11e-4)" "unprognostic (4.10e-2)" "unprognostic (3.02e-2)" "potential prognostic favorable (1.68e-5)" "unprognostic (2.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.36e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-1)" "unprognostic (1.16e-1)" "unprognostic (2.27e-1)" "unprognostic (1.10e-2)" "unprognostic (4.28e-1)" "unprognostic (4.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.91e-1)" "unprognostic (1.90e-1)" "unprognostic (7.58e-2)" "unprognostic (2.09e-1)" "unprognostic (8.49e-2)" "unprognostic (8.29e-2)" "unprognostic (4.03e-2)" "unprognostic (8.45e-2)" UHRF1 "FLJ21925, ICBP90, Np95, RNF106, TDRD22" ENSG00000276043 "Ubiquitin like with PHD and ring finger domains 1" Q96T88 19 4903080-4962154 "Disease related genes, Enzymes, Essential proteins, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair, Transcription, Transcription regulation, Ubl conjugation pathway" "Chromatin regulator, DNA-binding, Repressor, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 25.5;lymphoid tissue: 62.6" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 24.4;Erythrocyte progenitors: 57.7;Gastric progenitor cells: 28.2;Megakaryocyte progenitors: 24.5;Monocyte progenitors: 77.1;Neutrophil progenitors: 40.5;Thymocytes: 26.3" "Cell type enhanced" "Detected in many" "Erythrocytes: 57.7;Mononuclear phagocytes: 77.1;Neutrophils: 40.5" "Cell type enhanced" "Detected in some" "central nervous system macrophage: 11.1;ependymal cell: 8.3;leukocyte: 11.3;oligodendrocyte precursor cell: 8.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Group enriched" "Detected in many" 4 "dendritic cells: 4.8;T-cells: 2.3" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Thyroid gland - Mitotic cells (Thyroid)" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Granulosa cells: 12135508.7;Oocytes: 23374227.1" "Group enriched" "Detected in some" "bone marrow: 5974627.6;intestine: 3352252.1" "HPA049408, HPA055446" Enhanced Supported Nucleoplasm No Yes "Cluster 13: Non-specific - Mitochondria" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 27: Non-specific - Cell proliferation" 71 Nucleoplasm "HPA049408: , HPA055446: " "unprognostic (1.32e-1)" "unprognostic (3.84e-2)" "unprognostic (1.88e-1)" "unprognostic (1.01e-1)" "unprognostic (6.58e-2)" "unprognostic (3.81e-1)" "unprognostic (2.00e-1)" "unprognostic (1.03e-2)" "unprognostic (3.97e-3)" "validated prognostic unfavorable (1.02e-6)" "validated prognostic unfavorable (1.80e-4)" "potential prognostic unfavorable (1.83e-7)" "validated prognostic unfavorable (1.14e-4)" "validated prognostic unfavorable (9.65e-5)" "potential prognostic unfavorable (3.36e-4)" "unprognostic (1.69e-3)" "unprognostic (3.86e-2)" "unprognostic (1.36e-1)" "unprognostic (2.60e-1)" "potential prognostic unfavorable (1.08e-5)" "unprognostic (4.63e-3)" "unprognostic (2.06e-1)" "unprognostic (7.63e-3)" "potential prognostic unfavorable (2.26e-4)" "unprognostic (2.66e-3)" "unprognostic (2.68e-1)" "unprognostic (1.46e-1)" "unprognostic (6.36e-2)" UMPS ENSG00000114491 "Uridine monophosphate synthetase" P11172 3 124730433-124749273 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Pyrimidine biosynthesis" "Decarboxylase, Glycosyltransferase, Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 86.3;Syncytiotrophoblasts: 139.8" "Cell type enhanced" "Detected in all" "Trophoblast cells: 139.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Stomach - Mitotic cells (Stomach)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA036178, HPA036179" Uncertain Approved Cytosol NA NA 8700 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 3 Cytosol "HPA036178: , HPA036179: " "unprognostic (6.98e-2)" "unprognostic (9.82e-2)" "unprognostic (3.23e-1)" "unprognostic (3.47e-1)" "unprognostic (1.13e-1)" "unprognostic (5.23e-3)" "unprognostic (1.33e-1)" "unprognostic (1.25e-2)" "unprognostic (1.07e-3)" "unprognostic (8.59e-3)" "validated prognostic favorable (2.01e-4)" "validated prognostic favorable (1.55e-5)" "unprognostic (4.96e-2)" "unprognostic (8.86e-2)" "potential prognostic unfavorable (9.64e-4)" "unprognostic (4.16e-2)" "unprognostic (5.21e-2)" "unprognostic (4.49e-2)" "unprognostic (1.46e-1)" "unprognostic (3.64e-2)" "unprognostic (3.61e-2)" "unprognostic (1.77e-1)" "unprognostic (1.48e-1)" "unprognostic (2.92e-3)" "unprognostic (1.45e-2)" "unprognostic (1.28e-1)" "unprognostic (1.25e-1)" "unprognostic (1.27e-1)" "unprognostic (4.35e-1)" "unprognostic (5.05e-3)" "unprognostic (7.82e-2)" UNC119B "MGC5139, POC7B" ENSG00000175970 "Unc-119 lipid binding chaperone B" A6NIH7 12 120710458-120723640 "Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal efferent duct ciliated cells: 65.9;Fallopian tube ciliated cells: 62.7;Respiratory ciliated cells: 71.5" "Cell type enhanced" "Detected in all" "Ciliated cells: 71.5" "Cell type enhanced" "Detected in all" "ependymal cell: 53.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Macrophages, Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 2433723.6" "Low tissue specificity" "Detected in many" HPA077812 Enhanced Uncertain "Cytokinetic bridge,Mitotic spindle,Cytosol,Flagellar centriole,Mid piece,Principal piece,End piece,Annulus" Yes No "Cluster 33: Non-specific - ATP binding" "Cluster 65: Brain - Transcription" "Cluster 46: Brainstem - Mixed function" "Cluster 38: Non-specific - Transcription" "Cluster 107: Ciliated cells - Cilia assembly & function" 21 "Cytokinetic bridge, Mitotic spindle, Cytosol, Flagellar centriole, Annulus" "Mid piece, Principal piece, End piece" "HPA077812: " "unprognostic (3.21e-1)" "unprognostic (9.47e-2)" "unprognostic (1.58e-1)" "unprognostic (6.09e-2)" "unprognostic (1.10e-2)" "unprognostic (1.99e-1)" "unprognostic (2.45e-1)" "unprognostic (1.72e-2)" "unprognostic (1.63e-1)" "unprognostic (3.32e-3)" "validated prognostic favorable (7.13e-9)" "validated prognostic favorable (1.86e-4)" "unprognostic (4.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.25e-3)" "unprognostic (2.14e-1)" "unprognostic (3.10e-1)" "unprognostic (7.06e-2)" "unprognostic (4.34e-3)" "unprognostic (9.71e-2)" "unprognostic (2.87e-2)" "unprognostic (2.68e-3)" "unprognostic (1.05e-1)" "unprognostic (1.93e-2)" "unprognostic (1.05e-1)" "potential prognostic unfavorable (9.09e-4)" "unprognostic (3.79e-2)" "unprognostic (2.41e-2)" "unprognostic (1.42e-1)" "unprognostic (1.27e-1)" "unprognostic (1.17e-1)" UNC13B "hmunc13, Munc13-2, UNC13, Unc13h2" ENSG00000198722 "Unc-13 homolog B" O14795 9 35161992-35405338 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 387.0;Alveolar cells type 2: 521.9;Cone photoreceptor cells: 447.1;Goblet cells: 456.0;Myonuclei: 537.4;Prostatic glandular cells: 845.4;Rod photoreceptor cells: 468.7;Transitional alveolar cells: 606.3" "Cell type enhanced" "Detected in many" "Alveolar cells: 606.3;Glandular cells: 845.4" "Cell type enriched" "Detected in all" 4 "endothelial cell: 673.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Prostate - Prostate glandular cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubules: 2765617.2" "Low tissue specificity" "Detected in many" "HPA024493, HPA062300" Approved Approved "Nucleoplasm,Golgi apparatus,Vesicles,Intermediate filaments" Yes No "Cluster 47: Testis - Mixed function" "Cluster 23: Choroid plexus - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 13 Vesicles "Nucleoplasm, Golgi apparatus, Intermediate filaments" "HPA024493: , HPA062300: " "unprognostic (3.47e-1)" "unprognostic (5.31e-3)" "unprognostic (4.01e-1)" "unprognostic (6.15e-2)" "unprognostic (6.81e-2)" "unprognostic (1.93e-1)" "unprognostic (1.01e-1)" "unprognostic (9.56e-2)" "potential prognostic favorable (1.16e-4)" "unprognostic (9.76e-2)" "potential prognostic favorable (4.58e-8)" "unprognostic (1.51e-3)" "potential prognostic favorable (6.90e-5)" "unprognostic (1.02e-1)" "unprognostic (1.42e-2)" "potential prognostic favorable (3.07e-4)" "unprognostic (9.71e-2)" "unprognostic (1.86e-1)" "unprognostic (6.17e-3)" "unprognostic (2.63e-1)" "unprognostic (7.07e-2)" "unprognostic (5.31e-2)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-2)" "unprognostic (8.83e-2)" "unprognostic (2.56e-2)" "unprognostic (1.06e-1)" "unprognostic (1.98e-1)" "unprognostic (1.86e-2)" "unprognostic (1.12e-1)" UNC80 "C2orf21, FLJ33496, KIAA1843, UNC-80" ENSG00000144406 "Unc-80 homolog, NALCN channel complex subunit" Q8N2C7 2 209771832-209999300 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 29.7;pituitary gland: 12.8;retina: 17.6" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 648.9;Brain excitatory neurons: 464.8;Brain inhibitory neurons: 467.5;Corticotrophs: 769.0;Gonadotrophs: 628.1;Lactotrophs: 786.5;Oligodendrocyte progenitor cells: 654.4;Other brain neurons: 345.9;Retinal bipolar cells: 317.4;Rod photoreceptor cells: 275.7;Sertoli cells: 806.8;Somatotrophs: 785.0;Thyrotrophs: 816.7" "Group enriched" "Detected in many" 4 "Adrenal endocrine cells: 648.9;Glial cells: 654.4;Neuronal cells: 467.5;Pituitary endocrine cells: 816.7;Reproductive supporting cells: 806.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 1.9;Prostate Adenocarcinoma (TCGA): 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 4.2;prostate cancer: 3.0" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells, Pancreas - Alpha cells, Pancreas - Beta cells, Prostate - Prostate glandular cells, Stomach - Gastric enteroendocrine cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Microglia and Neuropil: 702293.2;Neurons: 2784888.1" "Tissue enriched" "Detected in single" 927 "cerebral cortex: 92650.9" "HPA042472, HPA050959" Enhanced Approved "Nuclear bodies,Vesicles" NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nuclear bodies" Vesicles "HPA042472: , HPA050959: " "unprognostic (1.98e-1)" "potential prognostic favorable (5.79e-4)" "unprognostic (1.30e-2)" "unprognostic (1.97e-2)" "unprognostic (2.65e-1)" UNC93B1 UNC93 ENSG00000110057 "Unc-93 homolog B1, TLR signaling regulator" Q9H1C4 11 67991100-68004982 "Disease related genes, Essential proteins, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 74.4" "Cell type enhanced" "Detected in many" "Fallopian tube ciliated cells: 86.0;Hofbauer cells: 103.8;Macrophages: 83.3;Microglia: 79.6;pDCs: 179.6;Respiratory ciliated cells: 161.1" "Cell type enhanced" "Detected in many" "Ciliated cells: 161.1;dendritic cells: 179.6" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 92.3;leukocyte: 31.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 18.3" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Macrophages, Adipose visceral - Macrophages, Lung - Macrophages, Skeletal muscle - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1807232.4;Macrophages: 2100915.6" "Tissue enhanced" "Detected in many" "liver: 3667293.0" "HPA038716, HPA038717, HPA042803" Approved Approved Nucleoplasm No No "Cluster 29: Non-specific - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 6: Plasmacytoid dendritic cells - Viral sensing & interferon response" 111 Nucleoplasm "HPA038716: , HPA038717: , HPA042803: " "unprognostic (6.20e-2)" "potential prognostic unfavorable (6.68e-4)" "unprognostic (9.80e-2)" "unprognostic (2.66e-1)" "unprognostic (1.31e-1)" "unprognostic (2.27e-2)" "unprognostic (6.08e-2)" "unprognostic (9.72e-3)" "unprognostic (6.01e-2)" "unprognostic (8.79e-2)" "unprognostic (3.53e-2)" "unprognostic (4.92e-3)" "unprognostic (1.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (4.95e-2)" "potential prognostic unfavorable (5.61e-4)" "unprognostic (9.45e-2)" "unprognostic (5.27e-2)" "unprognostic (9.45e-3)" "potential prognostic unfavorable (5.19e-4)" "unprognostic (3.97e-1)" "unprognostic (1.07e-1)" "unprognostic (2.41e-1)" "unprognostic (6.18e-2)" "unprognostic (1.11e-1)" "unprognostic (7.01e-2)" "unprognostic (3.46e-3)" "unprognostic (1.02e-1)" "unprognostic (7.47e-2)" UNCX Uncx4.1 ENSG00000164853 "UNC homeobox" A6NJT0 7 1232872-1237326 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "brain: 22.0" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 10.7;Brain inhibitory neurons: 5.2;Loop of henle epithelial cells: 6.5;Other brain neurons: 3.5;Retinal horizontal cells: 2.0;Somatotrophs: 2.2;Thyrotrophs: 2.2" "Cell type enhanced" "Detected in some" "Neuronal cells: 10.7;Pituitary endocrine cells: 2.2;Renal nephron cells: 6.5" "Cell type enhanced" "Detected in some" "midbrain-derived inhibitory: 32.2;upper rhombic lip: 28.9" "Not detected" "Not detected" "Region enriched" "Detected in many" 5 "cerebellum: 36.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Bone cancer: 1.0;Leukemia: 1.7" "Kidney - Ascending Loop of Henle cells" "Region enriched" "Detected in single" 5 "cerebellum: 3.2" "Region enriched" "Detected in many" 8 "cerebellum: 11.5" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 897445.1" "Not detected" "Not detected" HPA063294 Approved Nucleoplasm NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 11: Neuronal - Sensory perception" "Cluster 2: Cerebellar granular cells - Neuronal signaling" Nucleoplasm "HPA063294: " UPF2 "DKFZP434D222, KIAA1408, RENT2, smg-3" ENSG00000151461 "UPF2 regulator of nonsense mediated mRNA decay" Q9HAU5 10 11920022-12043170 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "fallopian tube: 5242147.5" HPA067008 Supported "Vesicles,Primary cilium,Primary cilium tip,Cytosol,Cytoplasmic bodies" NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 52: Non-specific - Mitochondria" "Cluster 82: Dendritic cells - Antigen presentation" 37 Cytosol "Vesicles, Primary cilium, Primary cilium tip, Cytoplasmic bodies" "HPA067008: " "unprognostic (5.27e-2)" "unprognostic (1.77e-2)" "unprognostic (9.98e-2)" "unprognostic (1.06e-1)" "unprognostic (4.35e-1)" "unprognostic (6.81e-2)" "unprognostic (1.69e-2)" "potential prognostic favorable (1.03e-5)" "unprognostic (2.45e-2)" "potential prognostic unfavorable (1.85e-4)" "potential prognostic favorable (2.33e-6)" "unprognostic (2.31e-3)" "unprognostic (5.36e-3)" "potential prognostic unfavorable (3.55e-5)" "unprognostic (4.03e-2)" "unprognostic (2.52e-1)" "unprognostic (7.44e-3)" "unprognostic (1.54e-1)" "unprognostic (8.50e-2)" "unprognostic (1.76e-1)" "unprognostic (1.09e-2)" "unprognostic (2.00e-2)" "unprognostic (9.68e-3)" "unprognostic (3.20e-2)" "unprognostic (8.71e-2)" "unprognostic (6.89e-2)" "unprognostic (1.99e-1)" "unprognostic (1.17e-1)" "unprognostic (4.73e-1)" "unprognostic (1.02e-1)" "unprognostic (1.33e-1)" UPF3A "HUPF3A, RENT3A, UPF3" ENSG00000169062 "UPF3A regulator of nonsense mediated mRNA decay" Q9H1J1 13 114281601-114305817 "Predicted intracellular proteins" "mRNA transport, Nonsense-mediated mRNA decay, Transport" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late primary spermatocytes: 708.4" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 708.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Group enriched" "Detected in many" "lymphoid tissue: 435124.4;pancreas: 318814.0;salivary gland: 141742.6;Stomach: 260677.2" "HPA018325, HPA061316" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Primary cilium,Primary cilium tip,Basal body" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 67: Testis - Mixed function" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 19: Non-specific - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 14 "Nucleoplasm, Vesicles, Plasma membrane" "Primary cilium, Primary cilium tip, Basal body" "HPA018325: , HPA061316: " "unprognostic (3.38e-2)" "unprognostic (2.97e-1)" "unprognostic (2.69e-1)" "unprognostic (9.27e-2)" "unprognostic (1.27e-1)" "unprognostic (1.30e-1)" "validated prognostic favorable (2.23e-4)" "validated prognostic favorable (9.40e-4)" "unprognostic (5.65e-2)" "unprognostic (3.35e-1)" "potential prognostic favorable (5.46e-5)" "unprognostic (3.89e-3)" "unprognostic (2.50e-2)" "unprognostic (5.57e-3)" "unprognostic (4.39e-2)" "unprognostic (1.87e-1)" "unprognostic (8.63e-2)" "unprognostic (1.03e-1)" "unprognostic (4.62e-2)" "unprognostic (2.80e-1)" "unprognostic (8.21e-2)" "unprognostic (1.19e-2)" "unprognostic (5.24e-2)" "unprognostic (1.37e-2)" "unprognostic (5.02e-1)" "unprognostic (1.52e-1)" "unprognostic (2.45e-2)" "unprognostic (4.07e-1)" "unprognostic (1.89e-1)" "unprognostic (9.32e-2)" "unprognostic (3.16e-1)" UPF3B "HUPF3B, MRX62, MRX82, RENT3B, UPF3BP1, UPF3BP2, UPF3BP3, UPF3X" ENSG00000125351 "UPF3B regulator of nonsense mediated mRNA decay" Q9BZI7 X 119834022-119852998 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Nonsense-mediated mRNA decay, Transport" RNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oocytes: 225.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 1542119.3;Oocytes: 2106292.9" "Group enriched" "Detected in many" "intestine: 39933338.3;Stomach: 35042178.4" "HPA001592, HPA001800, HPA001882" Approved Enhanced Nucleoplasm,Nucleoli,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 4: Non-specific - mRNA splicing & Cell cycle" "Cluster 36: Non-specific - mRNA processing" "Cluster 41: Oocytes - Oogenesis" 26 Cytosol "Nucleoplasm, Nucleoli" "HPA001592: , HPA001800: , HPA001882: " "unprognostic (1.95e-1)" "unprognostic (1.50e-1)" "unprognostic (2.75e-1)" "unprognostic (1.76e-1)" "unprognostic (1.14e-2)" "unprognostic (2.40e-1)" "unprognostic (5.06e-2)" "unprognostic (1.26e-1)" "unprognostic (2.72e-1)" "unprognostic (9.85e-3)" "unprognostic (4.18e-3)" "unprognostic (6.41e-2)" "unprognostic (1.08e-2)" "potential prognostic unfavorable (9.86e-8)" "unprognostic (1.97e-2)" "unprognostic (6.58e-2)" "unprognostic (4.07e-3)" "unprognostic (1.30e-3)" "unprognostic (5.14e-2)" "unprognostic (1.49e-1)" "unprognostic (8.51e-2)" "unprognostic (1.37e-1)" "unprognostic (3.21e-3)" "unprognostic (1.84e-3)" "unprognostic (3.63e-1)" "unprognostic (1.96e-1)" "unprognostic (3.53e-3)" "unprognostic (7.37e-2)" "unprognostic (3.01e-1)" "unprognostic (2.27e-1)" "unprognostic (1.57e-1)" UPP1 "UDRPASE, UP, UPASE, UPP" ENSG00000183696 "Uridine phosphorylase 1" Q16831 7 48088628-48108736 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.3" "Cell type enriched" "Detected in many" 4 "Esophageal apical cells: 2390.0" "Cell type enriched" "Detected in all" 4 "Apical squamous epithelial cells: 2390.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Kidney Chromophobe (TCGA): 76.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cancer enhanced" "Detected in all" "Gallbladder cancer: 125.9" "Pituitary gland - Endothelial cells, Spleen - Neutrophils_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cell types: 618220.1;Distal tubules: 537289.4;Macrophages: 530281.9" "Group enriched" "Detected in some" "intestine: 2419377.8;lung: 1760742.8;lymphoid tissue: 2263714.9" "HPA054040, HPA055394" Enhanced Enhanced Nucleoplasm No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 84: Apical squamous epithelium - Cornification" 25 Nucleoplasm "HPA054040: , HPA055394: " "potential prognostic unfavorable (1.93e-4)" "unprognostic (2.93e-1)" "unprognostic (9.91e-2)" "unprognostic (1.56e-3)" "unprognostic (3.41e-1)" "unprognostic (5.97e-2)" "potential prognostic unfavorable (8.59e-4)" "unprognostic (6.04e-2)" "unprognostic (8.08e-2)" "unprognostic (3.92e-1)" "unprognostic (7.93e-2)" "unprognostic (3.52e-1)" "unprognostic (2.08e-2)" "unprognostic (1.17e-3)" "unprognostic (1.36e-2)" "validated prognostic unfavorable (4.45e-4)" "validated prognostic unfavorable (9.94e-5)" "unprognostic (6.88e-3)" "potential prognostic unfavorable (5.10e-4)" "unprognostic (3.09e-1)" "unprognostic (3.60e-3)" "unprognostic (1.34e-1)" "potential prognostic unfavorable (1.76e-4)" "unprognostic (2.37e-1)" "unprognostic (8.79e-2)" "unprognostic (1.31e-2)" "unprognostic (1.32e-1)" "unprognostic (2.99e-2)" "unprognostic (6.37e-2)" "unprognostic (3.91e-1)" "unprognostic (1.71e-3)" URI1 "C19orf2, FLJ10575, NNX3, PPP1R19, RMP, URI" ENSG00000105176 "URI1 prefoldin like chaperone" O94763 19 29923644-30016612 "Essential proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Protein phosphatase inhibitor, Repressor" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 477.7;Late spermatids: 625.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 625.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Liver - Hepatocytes, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 1665405.7" "Group enriched" "Detected in many" "intestine: 5622986.0;lymphoid tissue: 1792959.8;ovary: 3200779.5;salivary gland: 2097983.9" HPA071709 Approved Supported Nucleoplasm,Cytosol Yes No "Cluster 22: Eosinophils - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 87 Nucleoplasm Cytosol "HPA071709: " "unprognostic (2.49e-1)" "unprognostic (2.46e-1)" "unprognostic (1.61e-1)" "unprognostic (1.17e-2)" "unprognostic (1.87e-1)" "unprognostic (3.96e-2)" "unprognostic (1.05e-1)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (9.11e-4)" "potential prognostic favorable (5.53e-4)" "unprognostic (1.39e-2)" "unprognostic (2.14e-1)" "potential prognostic unfavorable (1.26e-4)" "unprognostic (1.14e-1)" "unprognostic (1.49e-1)" "unprognostic (4.51e-2)" "unprognostic (1.23e-2)" "potential prognostic unfavorable (1.29e-4)" "unprognostic (5.21e-2)" "unprognostic (9.64e-2)" "unprognostic (1.73e-1)" "unprognostic (2.29e-1)" "potential prognostic favorable (9.96e-6)" "unprognostic (1.66e-1)" "unprognostic (5.90e-3)" "unprognostic (1.77e-1)" "unprognostic (2.51e-1)" "unprognostic (1.99e-1)" "unprognostic (6.90e-2)" USF2 "bHLHb12, FIP" ENSG00000105698 "Upstream transcription factor 2, c-fos interacting" Q15853 19 35268962-35279821 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 401.1" "Cell type enhanced" "Detected in all" "Platelets: 401.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Neurons: 3633317.7" "Group enriched" "Detected in some" 24403 "lymphoid tissue: 1630754.7;ovary: 3249769.6" "HPA029764, HPA046567" Supported Nucleoplasm,Vesicles NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 8 Nucleoplasm Vesicles "HPA029764: , HPA046567: " "unprognostic (3.38e-2)" "unprognostic (1.65e-2)" "unprognostic (4.02e-1)" "unprognostic (1.50e-2)" "unprognostic (1.46e-1)" "unprognostic (5.20e-3)" "unprognostic (3.95e-2)" "unprognostic (2.66e-1)" "unprognostic (1.85e-1)" "unprognostic (1.90e-1)" "unprognostic (1.98e-2)" "unprognostic (1.73e-1)" "unprognostic (1.99e-2)" "unprognostic (2.63e-1)" "unprognostic (5.44e-2)" "unprognostic (3.28e-1)" "unprognostic (1.15e-2)" "unprognostic (1.60e-1)" "unprognostic (2.31e-1)" "unprognostic (1.76e-1)" "unprognostic (9.99e-2)" "unprognostic (2.43e-3)" "unprognostic (1.97e-1)" "unprognostic (2.23e-2)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.47e-1)" "unprognostic (3.56e-2)" "unprognostic (2.76e-1)" "unprognostic (4.08e-1)" "unprognostic (1.92e-1)" USH1C "AIE-75, DFNB18, harmonin, NY-CO-37, NY-CO-38, PDZ-73, PDZ73, PDZD7C" ENSG00000006611 "USH1 protein network component harmonin" Q9Y6N9 11 17493895-17544416 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Hearing" "Cancer-related genes, Deafness, Non-syndromic deafness, Retinitis pigmentosa, Usher syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 92.0;kidney: 50.5" "Cell type enhanced" "Detected in some" "Colonocytes: 219.8;Enteric stem cells: 114.3;Enteric transient amplifying cells: 142.3;Enterocytes: 448.1;Epididymal efferent duct absorptive cells: 88.7;Foveolar cells: 63.1;Goblet cells: 114.4;Müller glia: 192.8;Neuroendocrine cells: 88.3;Pancreatic islet cells: 69.2;Paneth cells: 85.1;Proximal tubule cells: 141.2;Tuft cells: 196.0" "Cell type enhanced" "Detected in some" "Enterocytes: 448.1;Glial cells: 192.8;Proliferating cells: 142.3;Renal nephron cells: 141.2;Secretory gland support: 196.0" "Cell type enhanced" "Detected in many" "astrocyte: 43.6;hippocampal CA4: 30.0;oligodendrocyte: 68.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "colorectal cancer: 76.6;Gastric cancer: 40.3" "Colon - Colon enterocytes, Kidney - Proximal tubular cells, Liver - Cholangiocytes, Stomach - Gastric mucous cells" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" "Glomeruli: 5414249.1;Proximal tubules: 21346171.1" "Tissue enriched" "Detected in some" "intestine: 4105217.7" "CAB013690, HPA027398, HPA027492, HPA028033" Enhanced Enhanced Cytosol No NA "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 9 Cytosol "CAB013690: , HPA027398: , HPA027492: , HPA028033: " "unprognostic (4.28e-1)" "unprognostic (1.15e-1)" "unprognostic (1.07e-1)" "unprognostic (3.93e-1)" "unprognostic (1.12e-3)" "unprognostic (2.70e-1)" "potential prognostic favorable (6.96e-9)" "unprognostic (1.07e-1)" "potential prognostic favorable (1.55e-4)" "potential prognostic unfavorable (9.34e-5)" "unprognostic (1.19e-1)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (9.45e-2)" "unprognostic (7.62e-2)" "unprognostic (6.08e-2)" "unprognostic (4.11e-1)" "unprognostic (4.99e-2)" "unprognostic (1.79e-1)" "unprognostic (2.46e-2)" "unprognostic (1.83e-1)" "unprognostic (2.36e-2)" USP10 "KIAA0190, UBPO" ENSG00000103194 "Ubiquitin specific peptidase 10" Q14694 16 84699986-84779922 "Enzymes, Essential proteins, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 577.7" "Cell type enhanced" "Detected in all" "Neutrophils: 577.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 747.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 747.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 27303766.2" "Tissue enhanced" "Detected in many" "blood vessel: 25563636.0" "HPA006731, HPA006749" Enhanced Supported Nucleoplasm,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 87 Cytosol Nucleoplasm "HPA006731: , HPA006749: " "unprognostic (5.89e-3)" "unprognostic (2.59e-2)" "unprognostic (1.79e-1)" "unprognostic (3.16e-1)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.14e-1)" "unprognostic (7.15e-2)" "unprognostic (1.08e-2)" "unprognostic (2.36e-1)" "potential prognostic favorable (1.57e-5)" "unprognostic (2.29e-1)" "unprognostic (8.75e-3)" "unprognostic (1.03e-2)" "unprognostic (4.33e-3)" "unprognostic (8.81e-2)" "unprognostic (3.92e-3)" "unprognostic (3.20e-2)" "unprognostic (6.21e-3)" "unprognostic (3.02e-1)" "unprognostic (3.48e-2)" "unprognostic (6.47e-3)" "unprognostic (7.90e-3)" "unprognostic (3.64e-2)" "unprognostic (1.23e-2)" "unprognostic (2.93e-2)" "unprognostic (4.86e-2)" "unprognostic (2.36e-1)" "unprognostic (6.18e-2)" "unprognostic (1.34e-1)" "unprognostic (3.99e-1)" USP11 UHX1 ENSG00000102226 "Ubiquitin specific peptidase 11" P51784 X 47232866-47248328 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 169.4" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Neurons: 75747219.5" "Group enriched" "Detected in all" "cerebral cortex: 9042507.2;kidney: 7635292.9;lymphoid tissue: 6154347.0;skeletal muscle: 4827590.9" "HPA003103, HPA037536" Enhanced Supported Supported Nucleoplasm,Cytosol NA NA 8100 "Cluster 5: Non-specific - Cell proliferation" "Cluster 65: Brain - Transcription" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 36: Non-specific - mRNA processing" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 109 Nucleoplasm Cytosol "HPA003103: , HPA037536: " "unprognostic (1.32e-1)" "unprognostic (1.57e-1)" "unprognostic (1.99e-1)" "unprognostic (2.83e-2)" "unprognostic (2.88e-1)" "unprognostic (2.02e-1)" "unprognostic (1.31e-1)" "unprognostic (3.91e-3)" "unprognostic (1.38e-1)" "unprognostic (1.97e-1)" "validated prognostic favorable (1.04e-4)" "validated prognostic favorable (1.04e-4)" "unprognostic (1.30e-1)" "unprognostic (4.96e-3)" "unprognostic (6.78e-2)" "unprognostic (3.11e-1)" "unprognostic (1.47e-1)" "unprognostic (9.47e-2)" "potential prognostic favorable (2.63e-4)" "unprognostic (1.87e-1)" "unprognostic (1.25e-1)" "unprognostic (6.89e-3)" "unprognostic (9.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.21e-1)" "unprognostic (4.61e-2)" "unprognostic (4.31e-2)" "unprognostic (3.22e-2)" "unprognostic (1.51e-1)" "unprognostic (7.78e-2)" "unprognostic (7.20e-2)" USP13 IsoT-3 ENSG00000058056 "Ubiquitin specific peptidase 13" Q92995 3 179653032-179804366 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Autophagy, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 9 "heart muscle: 39.8;skeletal muscle: 99.1;tongue: 101.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 65.3;Cardiomyocytes: 57.3;Myonuclei: 108.5;Oligodendrocyte progenitor cells: 59.4;Oligodendrocytes: 57.2;Thymic myoid cells: 106.1" "Cell type enhanced" "Detected in many" "Myocytes: 108.5;Stromal cells: 106.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 15.6" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Heart muscle - Cardiomyocytes, Kidney - Endothelial cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Keratinocytes: 33122159.9" "Group enriched" "Detected in some" "salivary gland: 5859054.5;skeletal muscle: 4002097.4" HPA004827 Enhanced Approved Nucleoplasm,Cytosol NA NA "Cluster 1: T-cells - Unknown function" "Cluster 30: Skeletal muscle - Striated muscle contraction" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 63: Non-specific - Protein processing" "Cluster 46: Skeletal myocytes - Muscle structure & formation" 45 "Nucleoplasm, Cytosol" "HPA004827: " "unprognostic (1.47e-1)" "unprognostic (1.78e-2)" "unprognostic (1.02e-1)" "unprognostic (8.71e-2)" "unprognostic (5.64e-2)" "unprognostic (1.34e-1)" "unprognostic (6.27e-2)" "unprognostic (3.52e-2)" "unprognostic (1.10e-1)" "unprognostic (3.14e-3)" "unprognostic (8.94e-2)" "unprognostic (3.45e-1)" "unprognostic (1.36e-3)" "validated prognostic unfavorable (4.11e-4)" "validated prognostic unfavorable (9.49e-5)" "unprognostic (5.91e-2)" "unprognostic (7.60e-3)" "unprognostic (2.43e-1)" "unprognostic (1.66e-1)" "unprognostic (2.40e-2)" "unprognostic (9.96e-2)" "unprognostic (4.27e-1)" "unprognostic (3.22e-1)" "unprognostic (2.85e-1)" "unprognostic (1.55e-2)" "unprognostic (1.14e-1)" "unprognostic (3.82e-3)" "unprognostic (4.73e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-1)" "unprognostic (8.66e-3)" USP14 "TGT, Ubp6" ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" HPA001308 Approved Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 4400000 "Cluster 33: Non-specific - ATP binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 49: Hindbrain - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 94 "Plasma membrane, Cytosol" "Endoplasmic reticulum" "HPA001308: " "unprognostic (3.79e-3)" "unprognostic (3.80e-1)" "unprognostic (1.44e-2)" "unprognostic (3.95e-2)" "unprognostic (1.03e-1)" "unprognostic (6.55e-2)" "unprognostic (1.89e-1)" "unprognostic (4.51e-2)" "potential prognostic unfavorable (1.61e-4)" "unprognostic (4.59e-2)" "potential prognostic favorable (3.82e-7)" "unprognostic (2.32e-1)" "unprognostic (2.38e-1)" "validated prognostic unfavorable (4.69e-4)" "validated prognostic unfavorable (1.61e-5)" "potential prognostic unfavorable (1.41e-4)" "unprognostic (2.35e-1)" "unprognostic (7.60e-2)" "unprognostic (1.55e-1)" "unprognostic (1.43e-2)" "unprognostic (3.38e-1)" "unprognostic (6.90e-2)" "unprognostic (1.20e-3)" "unprognostic (9.14e-2)" "unprognostic (1.61e-1)" "unprognostic (9.66e-2)" "unprognostic (2.09e-1)" "unprognostic (2.51e-1)" "unprognostic (3.50e-1)" "unprognostic (2.28e-1)" "unprognostic (2.42e-1)" USP15 "KIAA0529, UNPH4" ENSG00000135655 "Ubiquitin specific peptidase 15" Q9Y4E8 12 62260338-62417431 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 166.2" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 1325.1;Neutrophils: 4247.9" "Cell type enriched" "Detected in all" 4 "Neutrophils: 4247.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 300.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 300.7" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA006237, HPA006428, HPA071014" Approved Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA 320000 "Cluster 35: Neutrophils - Protein binding" "Cluster 15: Bone marrow - Innate immune response" "Cluster 5: Non-specific - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 24: Neutrophils - Innate immunity signal integration" 103 Cytosol "Nucleoplasm, Nuclear bodies" "HPA006237: , HPA006428: , HPA071014: " "unprognostic (1.88e-1)" "unprognostic (2.55e-2)" "unprognostic (2.99e-1)" "unprognostic (1.24e-1)" "unprognostic (2.29e-1)" "unprognostic (1.92e-1)" "unprognostic (2.28e-1)" "unprognostic (1.40e-2)" "unprognostic (2.69e-1)" "potential prognostic unfavorable (1.41e-5)" "unprognostic (7.43e-2)" "unprognostic (7.79e-2)" "unprognostic (2.27e-1)" "unprognostic (3.35e-3)" "unprognostic (1.51e-1)" "unprognostic (2.98e-1)" "unprognostic (2.89e-3)" "unprognostic (1.66e-1)" "unprognostic (1.30e-1)" "unprognostic (6.34e-2)" "unprognostic (2.78e-1)" "unprognostic (9.89e-2)" "unprognostic (1.25e-3)" "unprognostic (3.07e-1)" "unprognostic (5.25e-2)" "unprognostic (3.70e-2)" "unprognostic (3.12e-3)" "unprognostic (3.44e-1)" "unprognostic (2.92e-1)" "unprognostic (3.09e-2)" "unprognostic (1.54e-1)" USP16 Ubp-M ENSG00000156256 "Ubiquitin specific peptidase 16" Q9Y5T5 21 29024629-29054488 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 549.6;Late primary spermatocytes: 371.5" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 549.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 1901753.2" "Group enriched" "Detected in many" "lung: 743905.8;Stomach: 1658328.1" HPA021140 Supported Approved Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 13 "Nucleoplasm, Cytosol" "HPA021140: " "unprognostic (5.68e-2)" "unprognostic (2.53e-2)" "unprognostic (9.66e-2)" "unprognostic (3.55e-2)" "unprognostic (2.03e-1)" "unprognostic (9.29e-2)" "unprognostic (3.26e-2)" "unprognostic (1.23e-1)" "unprognostic (6.42e-3)" "unprognostic (1.89e-2)" "potential prognostic favorable (3.04e-5)" "unprognostic (1.26e-3)" "unprognostic (1.85e-1)" "unprognostic (6.62e-2)" "unprognostic (2.01e-1)" "unprognostic (4.03e-1)" "unprognostic (4.12e-2)" "unprognostic (1.21e-1)" "unprognostic (1.71e-2)" "unprognostic (4.82e-2)" "unprognostic (4.31e-1)" "unprognostic (2.07e-1)" "unprognostic (2.72e-1)" "unprognostic (8.19e-2)" "unprognostic (2.84e-2)" "unprognostic (2.49e-1)" "unprognostic (1.94e-1)" "unprognostic (2.94e-1)" "unprognostic (1.35e-2)" "unprognostic (1.51e-2)" "unprognostic (1.06e-1)" USP18 ENSG00000184979 "Ubiquitin specific peptidase 18" Q9UMW8 22 18150118-18177397 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 21.3;Oocytes: 59.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 21.3;Oocytes: 59.9" "Cell type enhanced" "Detected in many" "endothelial cell: 14.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Skin - Fibroblasts_2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 12 "lymphoid tissue: 1190.8" HPA044768 Uncertain Supported Vesicles,Cytosol NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 45: Liver - Metabolism & Coagulation" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 108: Fibroblasts - ECM organization" 16 Cytosol Vesicles "HPA044768: " "unprognostic (8.18e-2)" "unprognostic (2.56e-1)" "unprognostic (5.16e-1)" "unprognostic (3.22e-3)" "unprognostic (1.35e-1)" "unprognostic (1.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.20e-1)" "unprognostic (2.37e-1)" "unprognostic (4.22e-2)" "unprognostic (2.07e-2)" "unprognostic (1.87e-1)" "unprognostic (1.57e-1)" "unprognostic (5.32e-3)" "unprognostic (8.39e-2)" "unprognostic (8.95e-3)" "unprognostic (2.28e-2)" "unprognostic (1.27e-1)" "unprognostic (2.06e-2)" "unprognostic (1.72e-2)" "unprognostic (1.99e-1)" "unprognostic (7.95e-2)" "unprognostic (2.50e-2)" "unprognostic (1.46e-1)" "unprognostic (9.27e-2)" "unprognostic (4.77e-2)" "unprognostic (1.68e-1)" "unprognostic (3.53e-1)" "unprognostic (4.70e-3)" "unprognostic (3.07e-2)" "unprognostic (2.05e-3)" USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381711 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 157.6" "Group enriched" "Detected in many" 5 "Early spermatids: 576.2;Late spermatids: 1912.0" "Cell type enriched" "Detected in many" 8 "Spermatogenic cell types: 1912.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in all" "Myeloma: 14.9" "Heart muscle - Cardiomyocytes, Skin - Keratinocyte (granular), Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubules: 1368695.9;Skeletal myofibers: 1022565.0" "Not detected" "Not detected" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" 120 Cytosol "Plasma membrane" "HPA006777: , HPA007222: " "unprognostic (6.42e-2)" "unprognostic (5.66e-2)" "unprognostic (1.09e-1)" "unprognostic (1.55e-2)" "unprognostic (9.39e-2)" "unprognostic (1.11e-1)" "unprognostic (2.39e-1)" "unprognostic (1.48e-1)" "unprognostic (1.22e-3)" "unprognostic (2.27e-1)" "validated prognostic favorable (1.68e-8)" "validated prognostic favorable (2.13e-5)" "unprognostic (9.30e-2)" "unprognostic (2.57e-1)" "unprognostic (3.29e-3)" "unprognostic (5.64e-2)" "unprognostic (1.11e-1)" "unprognostic (5.59e-2)" "unprognostic (2.15e-1)" "unprognostic (3.00e-3)" "unprognostic (2.01e-1)" "unprognostic (2.75e-3)" "unprognostic (6.66e-2)" "unprognostic (2.03e-2)" "unprognostic (1.81e-1)" "unprognostic (9.43e-2)" "unprognostic (9.61e-3)" "unprognostic (1.58e-1)" "unprognostic (2.20e-1)" "unprognostic (8.22e-3)" "unprognostic (1.08e-1)" USP26 ENSG00000134588 "Ubiquitin specific peptidase 26" Q9BXU7 X 133023168-133097109 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Breast myoepithelial cells: 1.7;Differentiating spermatogonia: 19.9;Early primary spermatocytes: 4.5;Retinal horizontal cells: 2.0;Undifferentiated spermatogonia: 7.5" "Cell type enriched" "Detected in some" 9 "Spermatogenic cell types: 19.9" "Low cell type specificity" "Detected in single" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Sarcoma: 1.0" "Testis - Spermatocytes, Testis - Spermatogonia" "Cell type enriched" "Detected in single" 31049 "Smooth muscle cells: 3104903.1" "Group enriched" "Detected in some" 207 "blood vessel: 27814.6;Stomach: 13556.1" "HPA000424, HPA027310, HPA079124" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 65: Non-specific - Unknown function" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 3 Nucleoplasm Cytosol "HPA000424: , HPA027310: , HPA079124: " USP3 ENSG00000140455 "Ubiquitin specific peptidase 3" Q9Y6I4 15 63504511-63594640 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, DNA damage, Ubl conjugation pathway" "Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 628.7;Neutrophils: 1742.1" "Cell type enhanced" "Detected in all" "Neutrophils: 1742.1" "Cell type enhanced" "Detected in all" "upper rhombic lip: 395.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 927347.5" "Group enriched" "Detected in some" 81296 "bone marrow: 8954134.9;lymphoid tissue: 7305006.1" "HPA053275, HPA060513, HPA077975" Supported "Nucleoplasm,Midbody ring" "Intracellular and membrane" Enzyme Yes No "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 58: Non-specific - Nuclear processes" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 14 Nucleoplasm "Midbody ring" "HPA053275: , HPA060513: , HPA077975: " "unprognostic (1.48e-3)" "unprognostic (5.36e-3)" "unprognostic (3.30e-2)" "unprognostic (9.90e-3)" "unprognostic (2.43e-1)" "unprognostic (1.29e-1)" "unprognostic (2.47e-2)" "potential prognostic favorable (4.76e-4)" "unprognostic (6.13e-2)" "potential prognostic unfavorable (7.70e-4)" "unprognostic (1.09e-1)" "unprognostic (2.39e-3)" "unprognostic (1.01e-1)" "unprognostic (1.04e-1)" "unprognostic (8.08e-2)" "unprognostic (2.74e-2)" "unprognostic (2.69e-1)" "unprognostic (5.36e-2)" "unprognostic (7.15e-2)" "unprognostic (9.17e-2)" "unprognostic (1.06e-1)" "unprognostic (5.36e-2)" "unprognostic (1.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.26e-2)" "unprognostic (1.38e-1)" "unprognostic (4.73e-2)" "unprognostic (2.85e-2)" "unprognostic (6.90e-2)" "unprognostic (2.79e-3)" "unprognostic (7.77e-2)" USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277144-49340712 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophils: 497.8" "Cell type enhanced" "Detected in all" "Neutrophils: 497.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "liver: 9512845.6" "HPA018499, HPA074006" Approved Supported "Nucleoplasm,Vesicles,Basal body,Cytosol" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 23: Choroid plexus - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 38 Nucleoplasm "Vesicles, Basal body, Cytosol" "HPA018499: , HPA074006: " "unprognostic (3.90e-2)" "unprognostic (1.67e-1)" "unprognostic (4.86e-2)" "unprognostic (2.54e-2)" "unprognostic (5.97e-2)" "unprognostic (1.58e-1)" "unprognostic (4.67e-1)" "unprognostic (9.44e-3)" "unprognostic (9.54e-2)" "potential prognostic unfavorable (1.40e-4)" "potential prognostic favorable (6.08e-5)" "unprognostic (6.03e-2)" "potential prognostic favorable (1.54e-4)" "unprognostic (2.52e-2)" "unprognostic (2.46e-3)" "potential prognostic favorable (3.03e-4)" "potential prognostic unfavorable (9.47e-5)" "unprognostic (3.59e-1)" "unprognostic (2.79e-2)" "unprognostic (1.36e-1)" "unprognostic (2.95e-1)" "unprognostic (5.28e-2)" "unprognostic (4.31e-3)" "unprognostic (2.60e-3)" "unprognostic (1.24e-1)" "potential prognostic favorable (7.29e-4)" "unprognostic (4.67e-2)" "unprognostic (1.14e-1)" "unprognostic (1.20e-1)" "unprognostic (1.48e-1)" "unprognostic (2.19e-1)" USP40 FLJ10785 ENSG00000085982 "Ubiquitin specific peptidase 40" Q9NVE5 2 233475526-233566782 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "Stomach: 359508.7" HPA005821 Uncertain Approved "Vesicles,Focal adhesion sites" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 22: Epididymis - Mixed function" "Cluster 11: White matter - Signal transduction" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 7: Non-specific - Transcription" 2 Vesicles "Focal adhesion sites" "HPA005821: " "unprognostic (3.78e-1)" "unprognostic (2.33e-2)" "unprognostic (4.39e-2)" "unprognostic (4.85e-3)" "unprognostic (3.78e-1)" "unprognostic (2.94e-2)" "unprognostic (2.26e-1)" "unprognostic (2.20e-2)" "unprognostic (1.94e-2)" "potential prognostic unfavorable (1.67e-4)" "unprognostic (2.93e-3)" "unprognostic (2.01e-3)" "unprognostic (1.24e-2)" "unprognostic (9.80e-2)" "unprognostic (9.48e-2)" "unprognostic (5.37e-2)" "unprognostic (9.81e-2)" "unprognostic (3.29e-1)" "unprognostic (2.90e-1)" "unprognostic (5.68e-2)" "unprognostic (4.82e-2)" "unprognostic (6.03e-2)" "unprognostic (2.94e-2)" "unprognostic (1.33e-1)" "unprognostic (1.26e-2)" "unprognostic (7.78e-3)" "unprognostic (4.65e-2)" "unprognostic (2.22e-1)" "unprognostic (2.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.83e-2)" USP45 MGC14793 ENSG00000123552 "Ubiquitin specific peptidase 45" Q70EL2 6 99432325-99521728 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Disease variant, Leber congenital amaurosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 213.2;Cardiomyocytes: 366.8;Epicardial cells: 209.2;Oocytes: 234.9" "Cell type enhanced" "Detected in all" "Myocytes: 366.8;Oocytes: 234.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 35 "Collecting ducts: 4062.7;Proximal tubules: 2994.5" "Not detected" "Not detected" "HPA029602, HPA029604, HPA075668" Approved Supported Nucleoplasm,Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 11 "Nucleoplasm, Cytosol" "HPA029602: , HPA029604: , HPA075668: " "unprognostic (6.82e-2)" "unprognostic (1.53e-2)" "unprognostic (1.62e-1)" "unprognostic (1.61e-3)" "unprognostic (5.12e-2)" "unprognostic (8.67e-2)" "unprognostic (9.21e-3)" "unprognostic (1.67e-1)" "unprognostic (1.67e-2)" "unprognostic (1.49e-3)" "unprognostic (2.32e-1)" "unprognostic (5.35e-2)" "unprognostic (3.40e-1)" "unprognostic (1.80e-2)" "unprognostic (5.97e-2)" "unprognostic (1.21e-1)" "unprognostic (1.51e-3)" "unprognostic (1.26e-1)" "unprognostic (2.04e-1)" "unprognostic (1.34e-2)" "unprognostic (3.24e-1)" "unprognostic (1.51e-2)" "unprognostic (1.63e-3)" "unprognostic (2.54e-1)" "unprognostic (1.04e-2)" "unprognostic (1.44e-1)" "unprognostic (6.33e-3)" "unprognostic (2.12e-1)" "unprognostic (2.29e-2)" "unprognostic (6.94e-2)" "unprognostic (3.67e-3)" UTP15 "FLJ12787, FLJ23637, NET21" ENSG00000164338 "UTP15 small subunit processome component" Q8TED0 5 73565443-73583380 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 34.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 54.4" "Cell type enhanced" "Detected in many" "Myocytes: 54.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neurons: 4102500.8" "Tissue enhanced" "Detected in many" "intestine: 4840247.3" HPA044697 Approved "Nucleoli,Endoplasmic reticulum" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 3: Rhabdoid - Membrane components" "Cluster 17: Non-specific - RNA processing" 26 "Nucleoli, Endoplasmic reticulum" "HPA044697: " "unprognostic (2.02e-1)" "unprognostic (1.01e-1)" "unprognostic (4.50e-1)" "unprognostic (1.66e-2)" "unprognostic (3.10e-2)" "unprognostic (3.22e-2)" "unprognostic (9.12e-2)" "unprognostic (2.95e-1)" "unprognostic (1.81e-1)" "potential prognostic unfavorable (5.58e-5)" "unprognostic (1.65e-2)" "unprognostic (1.59e-1)" "unprognostic (4.18e-2)" "unprognostic (7.43e-2)" "unprognostic (6.20e-2)" "unprognostic (3.94e-3)" "unprognostic (2.43e-3)" "unprognostic (8.71e-2)" "unprognostic (6.12e-2)" "unprognostic (1.19e-2)" "unprognostic (4.24e-3)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (4.12e-2)" "unprognostic (3.86e-2)" "unprognostic (3.68e-1)" "unprognostic (2.37e-1)" "unprognostic (2.87e-1)" "unprognostic (1.76e-1)" "unprognostic (1.35e-2)" "unprognostic (3.89e-2)" UTP20 "1A6/DRIM, DRIM" ENSG00000120800 "UTP20 small subunit processome component" O75691 12 101280105-101386618 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lacrimal acinar cells: 211.1" "Cell type enhanced" "Detected in many" "Acinar cells: 211.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 8077301.1" "Tissue enhanced" "Detected in many" "fallopian tube: 3157028.7" HPA049341 Supported "Nucleoli,Plasma membrane" No No "Cluster 30: Non-specific - DNA binding" "Cluster 39: Testis - Nuclear processes" "Cluster 11: White matter - Signal transduction" "Cluster 38: Non-specific - Transcription" "Cluster 38: Secretory epithelial cells - Exocrine secretion" 12 Nucleoli "Plasma membrane" "HPA049341: " "unprognostic (7.55e-2)" "unprognostic (1.16e-2)" "unprognostic (6.62e-2)" "unprognostic (1.23e-2)" "unprognostic (2.69e-2)" "unprognostic (1.09e-1)" "unprognostic (2.68e-1)" "unprognostic (3.37e-1)" "unprognostic (8.81e-2)" "unprognostic (1.41e-1)" "potential prognostic favorable (1.28e-4)" "unprognostic (3.10e-2)" "unprognostic (1.50e-1)" "validated prognostic unfavorable (6.57e-6)" "validated prognostic unfavorable (3.84e-4)" "unprognostic (1.78e-1)" "unprognostic (3.60e-2)" "unprognostic (1.60e-1)" "unprognostic (4.02e-2)" "unprognostic (2.20e-2)" "unprognostic (5.91e-3)" "unprognostic (1.92e-2)" "unprognostic (8.86e-3)" "unprognostic (7.04e-2)" "unprognostic (6.27e-2)" "unprognostic (3.25e-3)" "unprognostic (4.54e-2)" "unprognostic (1.49e-1)" "unprognostic (3.86e-1)" "unprognostic (6.51e-2)" "unprognostic (1.84e-1)" UTP6 "C17orf40, HCA66" ENSG00000108651 "UTP6 small subunit processome component" Q9NYH9 17 31860904-31901708 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Bile duct cancer: 59.2" "Spleen - B-cells (Spleen), Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 520405.7" "Group enriched" "Detected in some" 2250 "intestine: 339051.8;lymphoid tissue: 137248.4;salivary gland: 198623.5" "HPA025936, HPA055806" Supported Enhanced "Nucleoli,Mitotic chromosome" Yes No "Cluster 13: Non-specific - Mitochondria" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 8 Nucleoli "Mitotic chromosome" "HPA025936: , HPA055806: " "unprognostic (3.93e-1)" "unprognostic (5.04e-2)" "unprognostic (9.90e-2)" "unprognostic (1.69e-2)" "unprognostic (4.34e-1)" "unprognostic (3.59e-1)" "unprognostic (3.33e-2)" "unprognostic (7.42e-3)" "unprognostic (4.50e-2)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (5.56e-8)" "unprognostic (1.07e-3)" "unprognostic (4.58e-1)" "validated prognostic unfavorable (3.80e-5)" "validated prognostic unfavorable (4.05e-5)" "unprognostic (1.13e-2)" "potential prognostic unfavorable (1.85e-4)" "unprognostic (5.07e-2)" "unprognostic (1.41e-2)" "unprognostic (1.13e-1)" "unprognostic (2.02e-2)" "unprognostic (1.88e-2)" "unprognostic (1.91e-3)" "unprognostic (1.65e-1)" "unprognostic (1.14e-1)" "potential prognostic favorable (7.66e-4)" "unprognostic (5.22e-2)" "unprognostic (1.79e-1)" "unprognostic (3.38e-1)" "unprognostic (6.44e-2)" "unprognostic (1.31e-1)" UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285335-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 1287.3" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "endothelial cell: 1762.0;pericyte: 1749.0;vascular associated smooth muscle cell: 2274.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 157.0" "Lineage enriched" "Detected in all" 4 "monocytes: 157.0" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Endothelial cells, Adipose visceral - Endothelial cells, Lung - Alveolar cells type 1, Skeletal muscle - Endothelial cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Supported "Nucleoplasm,Plasma membrane,Primary cilium,Basal body" NA NA 16000 "Cluster 40: Monocytes - Innate immune response" "Cluster 61: Non-specific - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 57 "Plasma membrane" "Nucleoplasm, Primary cilium, Basal body" "CAB016348: , HPA018894: " "unprognostic (3.61e-2)" "unprognostic (1.22e-1)" "unprognostic (6.66e-2)" "unprognostic (6.57e-2)" "unprognostic (1.19e-1)" "unprognostic (7.02e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-1)" "unprognostic (7.61e-2)" "unprognostic (4.24e-3)" "validated prognostic favorable (4.36e-7)" "validated prognostic favorable (5.33e-5)" "unprognostic (2.12e-1)" "unprognostic (1.57e-3)" "unprognostic (3.77e-1)" "unprognostic (7.65e-2)" "unprognostic (2.82e-1)" "unprognostic (2.57e-2)" "unprognostic (1.36e-1)" "unprognostic (7.01e-2)" "unprognostic (2.11e-1)" "unprognostic (1.28e-1)" "unprognostic (1.33e-1)" "unprognostic (2.99e-1)" "unprognostic (1.32e-2)" "unprognostic (2.63e-2)" "unprognostic (2.79e-1)" "unprognostic (4.08e-2)" "unprognostic (3.38e-1)" "unprognostic (2.90e-1)" "unprognostic (2.40e-1)" UTY "KDM6AL, KDM6C" ENSG00000183878 "Ubiquitously transcribed tetratricopeptide repeat containing, Y-linked" O14607 Y 13234577-13480673 "Enzymes, Predicted intracellular proteins" "Chromatin regulator, Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophils: 480.0;Sertoli cells: 663.6" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 663.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 330 "fallopian tube: 32963.3" "HPA000568, HPA001165" Supported Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 30: White matter - Myelination" "Cluster 47: Leukemia - Hemostasis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 2 Nucleoplasm "Nucleoli, Nucleoli rim" "HPA000568: , HPA001165: " "unprognostic (1.92e-1)" "unprognostic (2.89e-2)" "unprognostic (6.24e-2)" "unprognostic (1.14e-1)" "unprognostic (1.27e-2)" "potential prognostic favorable (8.45e-6)" "unprognostic (1.89e-1)" "unprognostic (2.97e-2)" "unprognostic (1.54e-1)" "unprognostic (3.61e-2)" "unprognostic (8.97e-3)" "unprognostic (3.28e-1)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (3.82e-1)" "unprognostic (1.17e-1)" "unprognostic (5.69e-2)" "unprognostic (2.21e-1)" "unprognostic (1.94e-2)" "unprognostic (5.24e-2)" "unprognostic (1.02e-2)" "unprognostic (3.15e-2)" "unprognostic (1.57e-1)" "unprognostic (1.55e-1)" VAX1 ENSG00000148704 "Ventral anterior homeobox 1" Q5SQQ9 10 117128521-117138301 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 10 "brain: 4.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.1;Brain inhibitory neurons: 3.4;Choroid plexus epithelial cells: 5.1;Ependymal cells: 2.6;Late spermatids: 3.1;Oligodendrocytes: 2.3;Other brain neurons: 5.7;Pituitary stem cells: 1.1" "Cell type enhanced" "Detected in some" "Ciliated cells: 5.1;Glial cells: 2.3;Neuronal cells: 5.7;Spermatogenic cell types: 3.1" "Cell type enhanced" "Detected in some" "CGE interneuron: 7.1;eccentric medium spiny neuron: 11.8;MGE interneuron: 14.7" "Cancer enhanced" "Detected in some" "Uterine Corpus Endometrial Carcinoma (TCGA): 1.8" "Region enhanced" "Detected in many" "hypothalamus: 18.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 7 "Bone cancer: 16.7" "Group enriched" "Detected in some" 6 "basal ganglia: 5.6;hypothalamus: 3.2;olfactory bulb: 1.5" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA028946 Uncertain Approved "Nucleoplasm,Nucleoli rim" Yes NA "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 109: Neurons - Neuronal signaling" "Nucleoli rim" Nucleoplasm "HPA028946: " "unprognostic (1.67e-1)" "unprognostic (1.22e-1)" VCAN "CSPG2, PG-M" ENSG00000038427 Versican P13611 5 83471618-83582303 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "blood vessel: 171.7" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 1036.0;Endometrial glandular cells: 530.7;Endometrial stromal cells: 1175.7;Fibroblasts: 494.7;Monocyte progenitors: 1285.0;monocytes: 3415.3;Oligodendrocyte progenitor cells: 2165.4" "Group enriched" "Detected in many" 4 "Glial cells: 2165.4;Mononuclear phagocytes: 3415.3;Stromal cells: 1175.7" "Cell type enhanced" "Detected in many" "cerebellar inhibitory: 854.8;committed oligodendrocyte precursor: 1174.2;oligodendrocyte precursor cell: 2704.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 240.0;myeloid DC: 89.0" "Group enriched" "Detected in many" 20 "dendritic cells: 89.0;monocytes: 240.0" "Cancer enhanced" "Detected in many" "Kidney cancer: 189.1" "Adrenal gland - Adrenal cortex cells, Prostate - Fibroblasts, Stomach - Fibroblasts, Testis - Peritubular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Smooth muscle cells: 1425268004.5" "Tissue enriched" "Detected in all" "blood vessel: 8339934629.9" "HPA004726, CAB008979" Supported Approved "Vesicles,Mid piece,Principal piece,End piece" "Secreted to blood" "No annotated function" NA NA 39000000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 7 "Vesicles, Mid piece, Principal piece, End piece" "CAB008979: , HPA004726: " "unprognostic (4.33e-2)" "unprognostic (1.54e-1)" "unprognostic (7.02e-2)" "unprognostic (4.84e-3)" "unprognostic (2.31e-2)" "unprognostic (5.36e-2)" "unprognostic (2.82e-1)" "unprognostic (2.65e-3)" "unprognostic (3.50e-2)" "unprognostic (3.49e-2)" "unprognostic (2.15e-1)" "unprognostic (1.96e-1)" "unprognostic (1.76e-1)" "unprognostic (1.67e-2)" "unprognostic (6.52e-2)" "unprognostic (6.29e-3)" "unprognostic (4.82e-3)" "unprognostic (2.13e-1)" "unprognostic (6.06e-2)" "unprognostic (2.58e-3)" "potential prognostic unfavorable (1.17e-6)" "unprognostic (5.90e-3)" "unprognostic (3.74e-2)" "unprognostic (1.62e-1)" "unprognostic (3.28e-1)" "unprognostic (7.66e-3)" "unprognostic (2.85e-3)" "potential prognostic unfavorable (7.37e-5)" "unprognostic (1.84e-1)" "unprognostic (2.84e-2)" "unprognostic (1.77e-2)" VCP "CDC48, IBMPFD, p97, TERA" ENSG00000165280 "Valosin containing protein" P55072 9 35053928-35072668 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Autophagy, DNA damage, DNA repair, Transport, Ubl conjugation pathway" Hydrolase "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 721.2" "Cell type enhanced" "Detected in all" "Trophoblast cells: 721.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB005593, HPA012728, HPA012814" Supported Supported "Nucleoplasm,Mitotic spindle,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" Yes No 66000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 21: Non-specific - Metabolism" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 509 "Nucleoplasm, Cytosol" "Mitotic spindle, Primary cilium tip, Primary cilium transition zone, Basal body" "CAB005593: , HPA012728: , HPA012814: " "unprognostic (3.03e-1)" "unprognostic (6.95e-2)" "unprognostic (1.94e-1)" "unprognostic (8.47e-2)" "unprognostic (7.83e-2)" "unprognostic (1.38e-1)" "unprognostic (1.89e-1)" "unprognostic (3.52e-2)" "unprognostic (3.18e-1)" "unprognostic (9.73e-3)" "unprognostic (2.56e-2)" "unprognostic (6.66e-2)" "unprognostic (1.12e-2)" "potential prognostic unfavorable (9.81e-5)" "unprognostic (9.26e-3)" "unprognostic (5.11e-3)" "potential prognostic unfavorable (8.37e-4)" "unprognostic (2.47e-1)" "unprognostic (3.37e-1)" "unprognostic (4.61e-3)" "unprognostic (1.91e-1)" "unprognostic (1.11e-3)" "unprognostic (8.02e-2)" "unprognostic (1.26e-1)" "unprognostic (3.47e-1)" "unprognostic (1.83e-1)" "unprognostic (3.45e-2)" "unprognostic (8.23e-2)" "unprognostic (3.32e-1)" "unprognostic (6.23e-2)" "unprognostic (1.26e-3)" VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 19.1" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 109.6;Neutrophils: 161.8" "Cell type enhanced" "Detected in all" "Neutrophils: 161.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in all" "cerebral cortex: 10941419.9" HPA023932 Uncertain Uncertain "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 43 "Plasma membrane" "Centrosome, Cytosol" "HPA023932: " "potential prognostic favorable (8.71e-4)" "unprognostic (4.61e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-2)" "unprognostic (2.15e-1)" "unprognostic (6.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.56e-1)" "unprognostic (7.91e-2)" "potential prognostic unfavorable (8.51e-4)" "potential prognostic favorable (3.18e-5)" "unprognostic (5.61e-2)" "unprognostic (9.45e-2)" "unprognostic (6.84e-2)" "unprognostic (1.03e-1)" "unprognostic (2.58e-2)" "unprognostic (8.49e-2)" "unprognostic (2.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.16e-2)" "unprognostic (5.52e-2)" "unprognostic (3.07e-2)" "unprognostic (3.03e-1)" "unprognostic (5.48e-3)" "unprognostic (5.00e-2)" "unprognostic (7.10e-2)" "unprognostic (2.35e-1)" "unprognostic (2.82e-2)" "unprognostic (5.22e-1)" "unprognostic (1.13e-2)" "unprognostic (1.18e-1)" VCPKMT "C14orf138, METTL21D, VCP-KMT" ENSG00000100483 "Valosin containing protein lysine methyltransferase" Q9H867 14 50108632-50116600 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 96.0" "Cell type enhanced" "Detected in all" "Neutrophils: 96.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Neurons: 22307.7;Oocytes: 62895.9" "Group enriched" "Detected in some" "cerebral cortex: 1803783.1;intestine: 478539.8;lung: 698929.5;lymphoid tissue: 1120221.1" "HPA001146, HPA076561" Uncertain Supported Cytosol NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 24: Neutrophils - Innate immunity signal integration" 7 Cytosol "HPA001146: , HPA076561: " "unprognostic (2.11e-2)" "unprognostic (3.20e-2)" "unprognostic (9.99e-2)" "unprognostic (3.70e-1)" "unprognostic (8.43e-2)" "unprognostic (6.18e-3)" "unprognostic (3.34e-3)" "unprognostic (2.56e-1)" "unprognostic (1.34e-1)" "unprognostic (1.03e-2)" "unprognostic (8.33e-2)" "unprognostic (3.82e-1)" "unprognostic (4.29e-2)" "unprognostic (5.70e-2)" "unprognostic (2.54e-1)" "unprognostic (1.69e-2)" "unprognostic (1.91e-1)" "unprognostic (1.03e-1)" "unprognostic (1.06e-1)" "unprognostic (3.88e-2)" "potential prognostic unfavorable (9.40e-5)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (1.40e-1)" "unprognostic (5.27e-2)" "unprognostic (1.71e-1)" "unprognostic (2.37e-2)" "unprognostic (4.45e-1)" "unprognostic (1.71e-1)" VDR "NR1I1, PPP1R163" ENSG00000111424 "Vitamin D receptor" P11473 12 47841537-47943048 "Disease related genes, FDA approved drug targets, Human disease related genes, Nuclear receptors, Predicted intracellular proteins, Transcription factors, Transporters" "Transcription, Transcription regulation" "DNA-binding, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "parathyroid gland: 221.9" "Cell type enhanced" "Detected in many" "Breast lactating cells: 328.9;cDC: 110.5;Colonocytes: 182.3;Distal convoluted tubule cells: 210.9;Enteric stem cells: 147.4;Enteric transient amplifying cells: 121.9;Enterocytes: 159.5;Epididymal efferent duct absorptive cells: 117.5;Neutrophils: 168.1;Paneth cells: 170.2;Proximal tubule cells: 113.0" "Cell type enhanced" "Detected in many" "Renal nephron cells: 210.9;Secretory cells: 328.9" "Cell type enriched" "Detected in some" 8 "leukocyte: 11.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "classical monocyte: 3.5;eosinophil: 1.9;intermediate monocyte: 6.5;myeloid DC: 5.1;neutrophil: 6.6;non-classical monocyte: 6.7" "Group enriched" "Detected in many" 8 "dendritic cells: 5.1;granulocytes: 6.6;monocytes: 6.7" "Low cancer specificity" "Detected in many" "Adrenal gland - Adrenal cortex cells, Breast - Breast glandular cells, Pituitary gland - Lactotropes" "Region enhanced" "Detected in single" "olfactory bulb: 2.1" "Region enhanced" "Detected in some" "spinal cord: 5.8" "Cell type enriched" "Detected in some" "Distal tubules: 167063.9" "Tissue enriched" "Detected in single" 6839 "intestine: 683900.6" "CAB004617, HPA047740, HPA072102" Supported "Nucleoplasm,Intermediate filaments,Cytosol" NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 12: Non-specific - Vasculature" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 61 Nucleoplasm "Intermediate filaments, Cytosol" "CAB004617: , HPA047740: , HPA072102: " "potential prognostic favorable (6.06e-4)" "unprognostic (3.22e-2)" "unprognostic (1.47e-1)" "unprognostic (2.04e-2)" "unprognostic (3.81e-1)" "unprognostic (1.67e-2)" "potential prognostic unfavorable (4.25e-4)" "unprognostic (1.57e-2)" "unprognostic (8.25e-2)" "unprognostic (2.76e-1)" "unprognostic (1.54e-2)" "unprognostic (9.02e-2)" "unprognostic (1.68e-2)" "unprognostic (4.41e-2)" "unprognostic (6.06e-2)" "unprognostic (3.23e-1)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (8.72e-3)" "unprognostic (1.36e-2)" "unprognostic (7.09e-2)" "unprognostic (1.40e-3)" "unprognostic (9.50e-3)" "unprognostic (9.44e-2)" "unprognostic (3.30e-2)" "unprognostic (7.66e-2)" "unprognostic (1.01e-1)" "unprognostic (2.49e-1)" "unprognostic (1.88e-1)" "unprognostic (5.12e-2)" "unprognostic (1.33e-1)" "unprognostic (3.41e-1)" VGF "SCG7, SgVII" ENSG00000128564 "VGF nerve growth factor inducible" O15240 7 101162509-101165569 "Plasma proteins, Predicted secreted proteins" "Antibiotic, Antimicrobial, Growth factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 143.5;pituitary gland: 91.1" "Cell type enriched" "Detected in some" 8 "Pancreatic islet cells: 910.9" "Cell type enriched" "Detected in many" 8 "Pancreatic islet cells: 910.9" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in many" 6 "Skin Cutaneous Melanoma (TCGA): 472.9" "Region enriched" "Detected in all" 6 "hypothalamus: 2693.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 141.0;skin cancer: 234.3" "Adrenal gland - Adrenal medulla cells, Colon - Colon enteroendocrine cells, Thyroid gland - Parafollicular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Astrocytes and Neuropil: 38950625.1;Microglia and Neuropil: 27687542.7;Neurons: 16377585.6;Pancreatic islets: 12084414.3" "Tissue enriched" "Detected in many" "cerebral cortex: 163760971.0" "HPA055177, HPA072505" Enhanced Enhanced "Golgi apparatus,Vesicles" "Secreted to blood" "Growth factor" NA NA 1270000 1800000 "Cluster 78: Brain - Neuronal signaling" "Cluster 56: Hypothalamus - Neuropeptide signaling" "Cluster 16: Thyroid cancer - Neuronal signaling" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 16 "Golgi apparatus, Vesicles" "HPA055177: , HPA072505: " "unprognostic (2.35e-2)" "unprognostic (2.12e-2)" "unprognostic (2.09e-1)" "unprognostic (6.75e-3)" "unprognostic (3.12e-2)" "potential prognostic unfavorable (6.57e-4)" "unprognostic (2.22e-2)" "unprognostic (6.16e-1)" "unprognostic (4.87e-2)" "potential prognostic unfavorable (1.18e-5)" "unprognostic (1.71e-2)" "unprognostic (3.65e-2)" "unprognostic (1.68e-1)" "potential prognostic favorable (7.93e-4)" "unprognostic (1.08e-1)" "potential prognostic unfavorable (4.45e-6)" "unprognostic (4.52e-2)" "unprognostic (3.05e-1)" "unprognostic (4.78e-3)" "unprognostic (3.97e-1)" "unprognostic (1.13e-1)" "unprognostic (1.45e-2)" "unprognostic (6.30e-2)" VHL VHL1 ENSG00000134086 "Von Hippel-Lindau tumor suppressor" P40337 3 10141778-10153667 "Cancer-related genes, Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Cancer-related genes, Congenital erythrocytosis, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 77221.3;Oocytes: 94677.9" "Group enriched" "Detected in some" "bone marrow: 85902.6;lymphoid tissue: 61608.5" "HPA031631, HPA031632, HPA068954" Approved Enhanced "Nucleoplasm,Microtubules,Primary cilium,Primary cilium tip,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 34: Non-specific - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 153 Nucleoplasm "Microtubules, Primary cilium, Primary cilium tip, Cytosol" "HPA031631: , HPA031632: , HPA068954: " "unprognostic (5.51e-3)" "unprognostic (1.26e-3)" "unprognostic (8.18e-2)" "unprognostic (4.43e-3)" "unprognostic (4.47e-2)" "unprognostic (1.65e-1)" "unprognostic (2.74e-1)" "unprognostic (1.00e-1)" "unprognostic (5.13e-2)" "unprognostic (3.57e-3)" "unprognostic (1.66e-1)" "unprognostic (8.11e-2)" "unprognostic (1.55e-1)" "potential prognostic unfavorable (6.76e-9)" "unprognostic (5.46e-3)" "unprognostic (1.49e-1)" "unprognostic (1.24e-2)" "unprognostic (2.27e-1)" "unprognostic (5.51e-3)" "unprognostic (1.28e-2)" "unprognostic (1.17e-2)" "unprognostic (7.71e-3)" "unprognostic (2.00e-2)" "unprognostic (8.81e-3)" "potential prognostic favorable (8.78e-4)" "unprognostic (9.08e-2)" "unprognostic (1.40e-1)" "unprognostic (5.46e-3)" "unprognostic (1.55e-1)" "unprognostic (3.51e-3)" "unprognostic (1.67e-2)" VIRMA "DKFZP434I116, fSAP121, KIAA1429" ENSG00000164944 "Vir like m6A methyltransferase associated" Q69YN4 8 94487689-94553529 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 7688884.0" "Low tissue specificity" "Detected in many" HPA031530 Approved Supported "Nucleoplasm,Nuclear bodies" No No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" 235 "Nuclear bodies" Nucleoplasm "HPA031530: " "unprognostic (4.61e-2)" "unprognostic (1.08e-2)" "unprognostic (2.62e-2)" "unprognostic (2.45e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (4.74e-3)" "unprognostic (3.92e-1)" "potential prognostic unfavorable (6.74e-5)" "potential prognostic favorable (1.91e-5)" "unprognostic (1.23e-2)" "unprognostic (2.46e-2)" "unprognostic (1.48e-2)" "unprognostic (2.50e-2)" "unprognostic (2.07e-3)" "unprognostic (4.26e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.67e-5)" "unprognostic (2.33e-1)" "unprognostic (7.16e-3)" "potential prognostic unfavorable (1.09e-4)" "unprognostic (4.48e-2)" "unprognostic (2.09e-2)" "unprognostic (1.64e-1)" "unprognostic (1.08e-1)" "unprognostic (2.90e-1)" "unprognostic (3.16e-1)" "unprognostic (1.52e-2)" "unprognostic (7.04e-2)" VLDLR "CARMQ1, CHRMQ1, VLDLRCH" ENSG00000147852 "Very low density lipoprotein receptor" P98155 9 2621182-2660056 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol metabolism, Endocytosis, Host-virus interaction, Lipid metabolism, Lipid transport, Steroid metabolism, Sterol metabolism, Transport" Receptor "Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 32.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 220.3;Cone photoreceptor cells: 62.1;Epicardial cells: 97.8;Esophageal apical cells: 71.3;Gonadotrophs: 61.6;Myonuclei: 61.0;Pancreatic islet cells: 95.7" "Cell type enhanced" "Detected in many" "Myocytes: 220.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 6.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.3" "Low cancer specificity" "Detected in many" "Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Capillaries: 3837571.9;Cardiomyocytes: 9629867.7" "Group enriched" "Detected in some" 27287 "heart muscle: 4270688.2;ovary: 1186782.2" "CAB032462, HPA051312" Uncertain Uncertain "Vesicles,Cytokinetic bridge,Centriolar satellite" Yes NA 320000 "Cluster 61: Non-specific - Transcription" "Cluster 30: White matter - Myelination" "Cluster 15: Kidney cancer - Membrane components" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 7 Vesicles "Cytokinetic bridge, Centriolar satellite" "CAB032462: , HPA051312: " "unprognostic (2.31e-2)" "unprognostic (3.45e-2)" "unprognostic (8.68e-2)" "unprognostic (1.61e-3)" "unprognostic (4.50e-2)" "unprognostic (2.32e-1)" "unprognostic (1.01e-1)" "unprognostic (1.23e-1)" "unprognostic (6.86e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (3.48e-5)" "unprognostic (1.48e-1)" "unprognostic (6.71e-2)" "unprognostic (3.95e-1)" "unprognostic (1.95e-1)" "unprognostic (2.97e-1)" "unprognostic (8.20e-2)" "unprognostic (3.09e-1)" "unprognostic (1.82e-1)" "unprognostic (8.90e-2)" "unprognostic (3.65e-1)" "unprognostic (1.52e-2)" "unprognostic (4.88e-2)" "unprognostic (3.93e-2)" "unprognostic (2.80e-1)" "unprognostic (3.09e-3)" "unprognostic (1.43e-2)" "unprognostic (1.80e-1)" "potential prognostic unfavorable (2.11e-4)" "unprognostic (7.28e-2)" VN1R1 "V1RL1, VNR19I1, ZVNH1, ZVNR1" ENSG00000178201 "Vomeronasal 1 receptor 1" Q9GZP7 19 57454790-57457140 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Pheromone response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 6.6;retina: 7.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062209 Uncertain Nucleoplasm,Vesicles NA NA "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 32: Endothelial cells - Angiogenesis & vascular immunity" Vesicles Nucleoplasm "HPA062209: " "unprognostic (2.93e-1)" "unprognostic (9.62e-2)" "unprognostic (1.69e-1)" "unprognostic (5.23e-1)" "unprognostic (7.36e-2)" "unprognostic (2.05e-1)" "unprognostic (9.87e-2)" "unprognostic (6.87e-3)" "unprognostic (5.26e-3)" VPS13A "BLTP5A, CHAC, KIAA0986" ENSG00000197969 "Vacuolar protein sorting 13 homolog A" Q96RL7 9 77177445-77421537 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Lipid transport, Transport" "Disease variant, Epilepsy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Myonuclei: 608.1" "Cell type enhanced" "Detected in all" "Myocytes: 608.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "cerebral cortex: 11275881.3" "HPA021652, HPA021662" Supported Supported Mitochondria NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 18 Mitochondria "HPA021652: , HPA021662: " "unprognostic (2.21e-2)" "unprognostic (2.57e-1)" "unprognostic (1.41e-2)" "unprognostic (2.03e-2)" "unprognostic (2.34e-1)" "unprognostic (3.04e-1)" "unprognostic (4.50e-2)" "unprognostic (9.11e-2)" "unprognostic (7.27e-2)" "unprognostic (5.72e-2)" "potential prognostic favorable (6.84e-6)" "unprognostic (9.21e-3)" "unprognostic (8.53e-2)" "unprognostic (8.69e-3)" "unprognostic (7.55e-2)" "unprognostic (5.50e-2)" "unprognostic (3.72e-2)" "unprognostic (8.95e-2)" "unprognostic (1.94e-2)" "unprognostic (7.84e-3)" "unprognostic (4.98e-2)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.06e-1)" "unprognostic (8.95e-3)" "unprognostic (4.88e-1)" "unprognostic (1.36e-1)" "unprognostic (3.60e-1)" "unprognostic (2.91e-1)" "unprognostic (1.38e-1)" "unprognostic (2.38e-1)" VPS37A "FLJ32642, HCRP1, PQBP2, SPG53" ENSG00000155975 "VPS37A subunit of ESCRT-I" Q8NEZ2 8 17246931-17302427 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA024705, HPA024781" Supported Approved "Nucleoplasm,Vesicles,Centrosome,Cytosol,Acrosome,Equatorial segment,Perinuclear theca,Flagellar centriole,Mid piece,Principal piece,End piece" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 42: Retina - Visual perception" "Cluster 16: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 32 "Vesicles, Centrosome, Acrosome, Flagellar centriole" "Nucleoplasm, Cytosol, Equatorial segment, Perinuclear theca, Mid piece, Principal piece, End piece" "HPA024705: , HPA024781: " "unprognostic (4.47e-3)" "unprognostic (9.89e-2)" "unprognostic (3.36e-3)" "unprognostic (3.64e-3)" "unprognostic (9.54e-3)" "unprognostic (3.56e-2)" "unprognostic (2.53e-2)" "unprognostic (9.34e-2)" "unprognostic (2.62e-1)" "potential prognostic unfavorable (5.58e-4)" "potential prognostic favorable (2.52e-4)" "unprognostic (7.10e-3)" "unprognostic (8.99e-2)" "unprognostic (1.04e-2)" "unprognostic (1.96e-3)" "unprognostic (4.88e-1)" "unprognostic (2.19e-1)" "unprognostic (3.17e-1)" "unprognostic (7.46e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-3)" "unprognostic (8.59e-2)" "unprognostic (1.30e-2)" "unprognostic (2.61e-1)" "unprognostic (3.91e-2)" "unprognostic (5.32e-2)" "unprognostic (1.91e-2)" "unprognostic (4.64e-2)" "unprognostic (2.54e-1)" "unprognostic (1.01e-1)" "unprognostic (3.26e-2)" VPS37B FLJ12750 ENSG00000139722 "VPS37B subunit of ESCRT-I" Q9H9H4 12 122865330-122896127 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial glandular cells: 244.2;Esophageal apical cells: 355.5;Neutrophils: 316.7" "Low cell type specificity" "Detected in many" "Cell type enhanced" "Detected in all" "leukocyte: 80.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Large ducts: 1101715.6" "Tissue enhanced" "Detected in all" "lymphoid tissue: 6084576.0" "HPA038217, HPA038218" Enhanced Uncertain "Primary cilium,Cytosol" NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 103: Non-specific - Basic cellular processes" 47 Cytosol "Primary cilium" "HPA038217: , HPA038218: " "unprognostic (1.23e-1)" "unprognostic (9.35e-2)" "unprognostic (3.26e-1)" "unprognostic (3.55e-2)" "unprognostic (1.53e-1)" "unprognostic (7.09e-3)" "unprognostic (3.27e-1)" "unprognostic (1.54e-2)" "unprognostic (2.26e-1)" "unprognostic (1.36e-1)" "unprognostic (3.60e-3)" "potential prognostic favorable (8.69e-4)" "unprognostic (1.03e-2)" "unprognostic (8.80e-2)" "unprognostic (1.00e-2)" "unprognostic (5.70e-2)" "unprognostic (6.37e-3)" "unprognostic (1.30e-1)" "unprognostic (1.36e-1)" "unprognostic (1.12e-1)" "unprognostic (1.12e-1)" "unprognostic (5.81e-3)" "unprognostic (3.22e-3)" "unprognostic (2.30e-1)" "unprognostic (9.85e-2)" "unprognostic (2.46e-1)" "unprognostic (6.70e-3)" "unprognostic (4.50e-2)" "unprognostic (2.16e-1)" "unprognostic (3.75e-3)" "unprognostic (3.17e-2)" VPS37C FLJ20847 ENSG00000167987 "VPS37C subunit of ESCRT-I" A5D8V6 11 61130257-61161615 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 164.3" "Cell type enhanced" "Detected in all" "Neuronal cells: 164.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 1.4;eosinophil: 1.7;intermediate monocyte: 2.6;myeloid DC: 1.0;neutrophil: 3.8;non-classical monocyte: 2.4" "Group enriched" "Detected in many" 5 "dendritic cells: 1.0;granulocytes: 3.8;monocytes: 2.6" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Skin - Keratinocyte (other), Spleen - Fibroblasts_1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in all" "HPA043348, HPA062233" Approved Enhanced "Nucleoplasm,Golgi apparatus,Vesicles,Primary cilium" NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 27: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 79: Photoreceptor cells - Phototransduction" 85 "Nucleoplasm, Vesicles" "Golgi apparatus, Primary cilium" "HPA043348: , HPA062233: " "unprognostic (9.06e-2)" "unprognostic (1.50e-1)" "unprognostic (5.34e-2)" "unprognostic (3.33e-2)" "unprognostic (9.36e-2)" "unprognostic (1.22e-2)" "unprognostic (3.58e-1)" "unprognostic (7.67e-2)" "unprognostic (8.88e-2)" "unprognostic (5.50e-2)" "potential prognostic favorable (1.40e-5)" "unprognostic (2.93e-1)" "unprognostic (2.39e-2)" "potential prognostic unfavorable (4.18e-6)" "unprognostic (2.47e-2)" "unprognostic (2.15e-1)" "unprognostic (3.56e-3)" "unprognostic (4.47e-2)" "unprognostic (4.43e-1)" "unprognostic (1.28e-1)" "unprognostic (1.87e-2)" "unprognostic (9.82e-3)" "unprognostic (2.11e-1)" "unprognostic (1.16e-1)" "unprognostic (2.96e-1)" "unprognostic (1.66e-2)" "unprognostic (1.05e-1)" "unprognostic (1.49e-1)" "unprognostic (2.89e-1)" "unprognostic (6.65e-2)" "unprognostic (1.91e-1)" VPS4A "FLJ22197, SKD1, SKD1A, SKD2, VPS4, VPS4-1" ENSG00000132612 "Vacuolar protein sorting 4 homolog A" Q9UN37 16 69311350-69326939 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Cataract, Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 135.0" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB018751, CAB034411, HPA060092" Approved Supported Midbody Yes NA "Cluster 25: Non-specific - Unknown function" "Cluster 19: Skeletal muscle - Striated muscle contraction" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 97: Non-specific - Cellular respiration" 36 Midbody "CAB018751: , CAB034411: , HPA060092: " "unprognostic (2.00e-1)" "unprognostic (1.70e-2)" "unprognostic (1.57e-1)" "unprognostic (5.27e-2)" "unprognostic (9.45e-2)" "unprognostic (1.21e-1)" "unprognostic (2.52e-1)" "potential prognostic favorable (9.83e-6)" "unprognostic (2.38e-2)" "unprognostic (1.06e-1)" "potential prognostic favorable (1.99e-6)" "unprognostic (2.38e-2)" "potential prognostic favorable (9.79e-4)" "unprognostic (4.09e-3)" "unprognostic (1.51e-1)" "unprognostic (8.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.86e-3)" "unprognostic (1.52e-2)" "unprognostic (2.85e-2)" "unprognostic (9.38e-2)" "unprognostic (1.06e-1)" "unprognostic (3.15e-1)" "unprognostic (1.78e-2)" "unprognostic (2.23e-2)" "unprognostic (2.03e-1)" "unprognostic (2.17e-1)" "unprognostic (2.93e-1)" "unprognostic (2.57e-1)" "unprognostic (1.12e-2)" "unprognostic (2.11e-1)" VPS4B "SKD1, SKD1B, VPS4-2" ENSG00000119541 "Vacuolar protein sorting 4 homolog B" O75351 18 63389190-63422483 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Protein transport, Transport" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1139.3;Neutrophils: 356.8;Ocular epithelial cells: 427.4" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 1139.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA040393, CAB046445, HPA057649" Approved Approved Vesicles No No 32000 "Cluster 35: Neutrophils - Protein binding" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 13: Non-specific - Mixed function" "Cluster 100: Stratified epithelial cells - Barrier functions" 15 Vesicles "CAB046445: , HPA040393: , HPA057649: " "unprognostic (6.08e-2)" "unprognostic (3.01e-2)" "unprognostic (2.19e-2)" "unprognostic (7.62e-3)" "unprognostic (2.95e-2)" "unprognostic (4.81e-2)" "unprognostic (2.07e-1)" "unprognostic (1.22e-1)" "unprognostic (1.06e-1)" "unprognostic (3.22e-2)" "validated prognostic favorable (2.14e-7)" "validated prognostic favorable (8.77e-4)" "unprognostic (4.58e-2)" "unprognostic (1.55e-1)" "unprognostic (6.86e-2)" "unprognostic (1.14e-2)" "unprognostic (2.55e-1)" "unprognostic (4.79e-2)" "unprognostic (7.22e-2)" "unprognostic (4.45e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-3)" "unprognostic (2.55e-1)" "unprognostic (2.27e-1)" "unprognostic (3.32e-2)" "unprognostic (2.61e-2)" "unprognostic (2.32e-2)" "unprognostic (2.62e-1)" "unprognostic (3.84e-1)" "unprognostic (1.21e-1)" "unprognostic (8.17e-2)" VPS50 "CCDC132, DKFZp313I2429, FLJ20097, KIAA1861, VPS54L" ENSG00000004766 "VPS50 subunit of EARP/GARPII complex" Q96JG6 7 93232340-93361123 "Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Epilepsy, Intellectual disability, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglia and Neuropil: 20353158.3;Neurons: 19286029.6" "Tissue enhanced" "Detected in many" "cerebral cortex: 22932083.1" HPA026679 Approved Uncertain "Plasma membrane,Primary cilium,Basal body,Cytosol,Mid piece,Principal piece,End piece" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 18 "Plasma membrane, Cytosol" "Primary cilium, Basal body, Mid piece, Principal piece, End piece" "HPA026679: " "unprognostic (6.62e-2)" "unprognostic (1.05e-1)" "unprognostic (1.58e-2)" "potential prognostic unfavorable (6.08e-4)" "unprognostic (1.34e-2)" "unprognostic (8.82e-2)" "unprognostic (9.67e-3)" "unprognostic (1.57e-2)" "unprognostic (1.02e-2)" "unprognostic (1.94e-1)" "unprognostic (4.20e-3)" "unprognostic (8.52e-3)" "potential prognostic unfavorable (2.03e-6)" "unprognostic (2.41e-1)" "unprognostic (1.99e-1)" "unprognostic (2.75e-1)" "unprognostic (1.30e-1)" "unprognostic (1.30e-2)" "unprognostic (2.62e-2)" "unprognostic (2.22e-1)" "unprognostic (2.21e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-1)" "unprognostic (3.79e-1)" "unprognostic (9.41e-3)" "unprognostic (1.82e-1)" "unprognostic (3.60e-1)" "unprognostic (2.09e-2)" "unprognostic (1.38e-1)" VRK1 ENSG00000100749 "VRK serine/threonine kinase 1" Q99986 14 96797304-96954846 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Host-virus interaction, Mitosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 48.2" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 152.4;Early primary spermatocytes: 281.9;Erythrocyte progenitors: 268.2;Monocyte progenitors: 177.4;Neutrophil progenitors: 331.0;Oocytes: 345.4;Parietal cells: 353.6" "Cell type enhanced" "Detected in all" "Erythrocytes: 268.2;Gastric glandular cells: 353.6;Neutrophils: 331.0;Oocytes: 345.4;Spermatogenic cell types: 281.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Mitotic cells (Spleen), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 27520952.9" "Tissue enhanced" "Detected in many" "bone marrow: 6364063.4" "HPA000660, HPA017929" Enhanced Supported Nucleoplasm,Cytosol Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 58 Nucleoplasm Cytosol "HPA000660: , HPA017929: " "potential prognostic unfavorable (7.24e-4)" "unprognostic (2.49e-1)" "unprognostic (3.92e-2)" "unprognostic (3.67e-3)" "unprognostic (5.40e-2)" "unprognostic (9.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.93e-2)" "unprognostic (9.60e-3)" "unprognostic (2.93e-2)" "potential prognostic favorable (2.03e-7)" "unprognostic (1.64e-1)" "unprognostic (3.74e-2)" "validated prognostic unfavorable (2.59e-5)" "validated prognostic unfavorable (5.95e-5)" "unprognostic (2.72e-2)" "unprognostic (4.24e-3)" "potential prognostic favorable (1.32e-4)" "unprognostic (6.78e-2)" "unprognostic (1.74e-1)" "unprognostic (3.99e-3)" "unprognostic (7.19e-2)" "unprognostic (2.35e-3)" "unprognostic (2.50e-1)" "unprognostic (7.49e-2)" "unprognostic (8.63e-2)" "unprognostic (2.32e-1)" "unprognostic (1.80e-1)" "unprognostic (2.50e-1)" "unprognostic (1.93e-1)" "unprognostic (1.17e-1)" VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 94.8;fallopian tube: 30.5;pancreas: 28.4" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 152.7;Breast secretory cells: 100.6;Endometrial luminal cells: 239.7;Fallopian secretory cells: 103.4;Lacrimal acinar cells: 76.1;Pancreatic duct cells: 118.8;Prostatic club cells: 117.7;Respiratory deuterosomal cells: 101.6;Respiratory secretory cells: 98.6;Salivary ionocytes: 85.4;Submucosal glandular cells: 62.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 101.6;Ductal cells: 118.8;Glandular cells: 117.7;Ionocytes: 85.4;Luminal cells: 239.7;Secretory cells: 103.4" "Cell type enhanced" "Detected in some" "committed oligodendrocyte precursor: 1.8" "Group enriched" "Detected in many" 5 "Breast Invasive Carcinoma (TCGA): 100.1;Ovary Serous Cystadenocarcinoma (TCGA): 78.0;Uterine Corpus Endometrial Carcinoma (TCGA): 88.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "breast cancer: 51.0;ovarian cancer: 27.5;testis cancer: 27.6" "Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Prostate - Urothelial cells" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1193 "Collecting ducts: 49486.2;Fallopian tube cells: 189087.9" "Tissue enriched" "Detected in single" 525 "fallopian tube: 52545.6" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 55: Breast - Lactation" "Cluster 27: Breast cancer - Unknown function" "Cluster 52: Glandular & Luminal cells - Estrogen-regulated epithelial secretion" 6 "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: " "unprognostic (3.83e-2)" "unprognostic (3.49e-1)" "unprognostic (3.62e-1)" "unprognostic (9.13e-3)" "unprognostic (2.80e-1)" "unprognostic (2.22e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (9.34e-2)" "unprognostic (5.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.65e-2)" "unprognostic (3.02e-1)" "unprognostic (3.18e-2)" "unprognostic (9.04e-2)" "unprognostic (6.31e-2)" "unprognostic (1.87e-1)" "unprognostic (2.77e-2)" "unprognostic (2.28e-1)" "potential prognostic unfavorable (2.25e-4)" VTI1B VTI2 ENSG00000100568 "Vesicle transport through interaction with t-SNAREs 1B" Q9UEU0 14 67647085-67674820 "Essential proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 419.3;Late spermatids: 730.0" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 419.3;Spermatogenic cell types: 730.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast), Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "HPA044121, HPA048150, HPA060118" Approved Enhanced "Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 14: Neurons - Synaptic function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 54 "Golgi apparatus, Vesicles" "HPA044121: , HPA048150: , HPA060118: " "unprognostic (2.51e-1)" "unprognostic (1.78e-1)" "unprognostic (4.55e-1)" "unprognostic (2.65e-1)" "unprognostic (1.89e-1)" "unprognostic (4.16e-2)" "unprognostic (1.02e-1)" "unprognostic (1.79e-1)" "unprognostic (1.41e-3)" "potential prognostic unfavorable (1.88e-4)" "unprognostic (1.47e-3)" "unprognostic (1.97e-3)" "potential prognostic favorable (2.72e-6)" "unprognostic (1.27e-2)" "unprognostic (1.29e-2)" "unprognostic (2.25e-3)" "unprognostic (1.65e-1)" "unprognostic (8.25e-2)" "unprognostic (1.54e-1)" "unprognostic (7.82e-2)" "unprognostic (1.21e-2)" "unprognostic (1.97e-2)" "unprognostic (1.09e-1)" "unprognostic (5.56e-2)" "unprognostic (2.69e-2)" "unprognostic (7.44e-2)" "unprognostic (2.00e-1)" "unprognostic (5.42e-3)" "unprognostic (1.27e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" VWA3B "DKFZp686F2227, MGC26733" ENSG00000168658 "Von Willebrand factor A domain containing 3B" Q502W6 2 98087116-98313299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "choroid plexus: 8.8;fallopian tube: 20.9;testis: 28.8" "Cell type enhanced" "Detected in many" "Early spermatids: 596.2;Endometrial ciliated cells: 181.6;Ependymal cells: 361.7;Fallopian tube ciliated cells: 253.7;Late primary spermatocytes: 230.0;Late spermatids: 1801.3;Respiratory ciliated cells: 643.0" "Group enriched" "Detected in many" 53 "Ciliated cells: 643.0;Spermatogenic cell types: 1801.3" "Cell type enriched" "Detected in many" 5 "ependymal cell: 412.1" "Cancer enhanced" "Detected in some" "Lung Adenocarcinoma (TCGA): 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Region enriched" "Detected in many" 4 "hippocampal formation: 7.1" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 42187 "Fallopian tube cells: 4218714.6" "Tissue enriched" "Detected in single" 4289 "fallopian tube: 428864.6" "HPA036700, HPA036701" Approved Approved Nucleoplasm,Cytosol NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 24: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" "Nucleoplasm, Cytosol" "HPA036700: , HPA036701: " "unprognostic (1.71e-1)" "unprognostic (3.67e-3)" "unprognostic (2.79e-3)" "unprognostic (6.28e-2)" "unprognostic (3.29e-1)" WARS1 "IFI53, IFP53, WARS" ENSG00000140105 "Tryptophanyl-tRNA synthetase 1" P23381 14 100333790-100376805 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Intellectual disability, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 304.7" "Cell type enhanced" "Detected in all" "Endometrial luminal cells: 168.6;Late primary spermatocytes: 173.1;Late spermatids: 168.6;monocytes: 301.0;Pituicytes/FSCs: 166.5;Schwann cells: 282.7;Vascular endothelial cells: 232.9" "Cell type enhanced" "Detected in all" "Glial cells: 282.7;Mononuclear phagocytes: 301.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "intermediate monocyte: 1347.2;non-classical monocyte: 1617.8" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Endothelial cells, Colon - Endothelial cells, Heart muscle - Endothelial cells, Kidney - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA005573, HPA018944" Enhanced Enhanced Cytosol No No 21000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 13: Non-specific - Mixed function" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 9 Cytosol "HPA005573: , HPA018944: " "unprognostic (9.57e-2)" "unprognostic (2.74e-2)" "unprognostic (1.92e-1)" "unprognostic (9.60e-2)" "unprognostic (8.42e-2)" "unprognostic (8.00e-2)" "unprognostic (1.88e-1)" "unprognostic (4.79e-2)" "unprognostic (5.50e-2)" "unprognostic (5.41e-3)" "unprognostic (6.04e-2)" "unprognostic (2.95e-2)" "unprognostic (3.60e-3)" "unprognostic (1.13e-2)" "unprognostic (6.07e-2)" "unprognostic (1.27e-1)" "unprognostic (9.88e-2)" "unprognostic (1.57e-2)" "unprognostic (4.36e-1)" "unprognostic (2.31e-2)" "unprognostic (6.14e-3)" "unprognostic (1.86e-1)" "unprognostic (3.10e-1)" "unprognostic (1.49e-2)" "unprognostic (8.04e-2)" "unprognostic (3.59e-2)" "unprognostic (2.25e-2)" "unprognostic (9.89e-2)" "unprognostic (1.42e-2)" WASHC5 "KIAA0196, SPG8" ENSG00000164961 "WASH complex subunit 5" Q12768 8 125024260-125091819 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Intellectual disability, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 139.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Tissue enhanced" "Detected in many" "lymphoid tissue: 12344467.4" "CAB034216, CAB034219" Supported Supported "Cytokinetic bridge,Mitotic spindle,Primary cilium,Centrosome,Basal body,Cytosol" Yes NA "Cluster 33: Non-specific - ATP binding" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 32 Cytosol "Cytokinetic bridge, Mitotic spindle, Primary cilium, Centrosome, Basal body" "CAB034216: , CAB034219: " "unprognostic (1.06e-1)" "unprognostic (2.57e-3)" "unprognostic (1.35e-2)" "unprognostic (3.01e-1)" "unprognostic (5.28e-2)" "unprognostic (9.89e-2)" "unprognostic (6.83e-2)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (6.14e-5)" "potential prognostic favorable (1.50e-6)" "unprognostic (1.73e-2)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (2.19e-2)" "unprognostic (6.11e-2)" "unprognostic (4.27e-2)" "unprognostic (9.14e-2)" "unprognostic (8.26e-2)" "unprognostic (9.85e-3)" "unprognostic (2.13e-3)" "unprognostic (1.43e-3)" "unprognostic (7.01e-2)" "unprognostic (1.40e-1)" "unprognostic (2.75e-1)" "unprognostic (4.14e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-1)" "unprognostic (1.05e-1)" "unprognostic (3.34e-1)" WBP1 WBP-1 ENSG00000239779 "WW domain binding protein 1" Q96G27 2 74458400-74460891 "Essential proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 22.7;Bergmann glia: 29.1;Brain excitatory neurons: 12.1;Brain inhibitory neurons: 13.1;Choroid plexus epithelial cells: 8.5;Ependymal cells: 24.6;Microglia: 14.5;Oligodendrocyte progenitor cells: 16.5;Oligodendrocytes: 26.4;Other brain neurons: 15.7" "Group enriched" "Detected in many" 4 "Ciliated cells: 24.6;Glial cells: 29.1;Neuronal cells: 15.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skeletal muscle - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA057067 Approved Approved Cytosol No No "Cluster 13: Non-specific - Mitochondria" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 98: Neurons - Neurotransmission & signaling" 7 Cytosol "HPA057067: " "unprognostic (7.20e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-1)" "unprognostic (7.46e-3)" "unprognostic (2.50e-3)" "unprognostic (1.34e-2)" "unprognostic (2.69e-1)" "potential prognostic favorable (3.37e-4)" "unprognostic (8.30e-2)" "unprognostic (5.75e-2)" "potential prognostic favorable (3.32e-7)" "unprognostic (2.08e-2)" "unprognostic (1.82e-2)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (6.19e-4)" "unprognostic (1.15e-1)" "unprognostic (1.03e-1)" "unprognostic (6.15e-2)" "unprognostic (1.19e-1)" "unprognostic (3.02e-1)" "unprognostic (9.72e-2)" "unprognostic (1.04e-1)" "unprognostic (4.00e-1)" "unprognostic (6.24e-2)" "unprognostic (3.91e-1)" "unprognostic (3.81e-2)" "unprognostic (2.47e-2)" "unprognostic (3.35e-3)" "unprognostic (8.92e-2)" "unprognostic (1.26e-2)" "unprognostic (6.10e-2)" WBP2 "GRAMD6, WBP-2" ENSG00000132471 "WW domain binding protein 2" Q969T9 17 75845699-75856507 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 342.2;Esophageal apical cells: 279.2;Late spermatids: 484.7;Platelets: 904.3" "Cell type enhanced" "Detected in all" "Platelets: 904.3;Spermatogenic cell types: 484.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 19379522.5" "Low tissue specificity" "Detected in all" "HPA065682, HPA068819" Approved Supported Nucleoplasm,Cytosol No No 97000 "Cluster 21: Neutrophils - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 27: Breast cancer - Unknown function" "Cluster 47: Platelets - Hemostasis" 28 "Nucleoplasm, Cytosol" "HPA065682: , HPA068819: " "unprognostic (2.00e-2)" "unprognostic (2.07e-2)" "unprognostic (1.70e-1)" "unprognostic (2.93e-1)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (2.24e-4)" "unprognostic (8.59e-2)" "unprognostic (5.01e-1)" "unprognostic (9.44e-3)" "unprognostic (2.13e-2)" "unprognostic (3.19e-3)" "unprognostic (1.60e-2)" "unprognostic (3.83e-2)" "unprognostic (8.48e-3)" "unprognostic (3.94e-2)" "unprognostic (1.97e-1)" "unprognostic (9.37e-2)" "unprognostic (9.64e-3)" "unprognostic (1.40e-1)" "unprognostic (2.79e-1)" "unprognostic (1.83e-1)" "unprognostic (2.56e-2)" "unprognostic (8.27e-2)" "unprognostic (1.34e-1)" "unprognostic (2.92e-2)" "unprognostic (5.67e-2)" "unprognostic (2.02e-1)" "unprognostic (3.95e-2)" "unprognostic (2.17e-1)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" WDR19 "DYF-2, FAP66, FLJ23127, IFT144, KIAA1638, NPHP13, ORF26, Oseg6, Pwdmp" ENSG00000157796 "WD repeat domain 19" Q8NEZ3 4 39182504-39285810 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant, Ectodermal dysplasia, Leber congenital amaurosis, Nephronophthisis, Senior-Loken syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ependymal cells: 212.7;Respiratory ciliated cells: 209.9;Somatotrophs: 184.2;Thyrotrophs: 215.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 212.7;Pituitary endocrine cells: 215.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 20515823.0" "Group enriched" "Detected in some" 100125 "fallopian tube: 10868206.8;lung: 9156749.9" "HPA039616, HPA058847" Approved Uncertain "Nucleoplasm,Centrosome,Basal body,Cytosol,Mid piece,Principal piece" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 75: Ovary - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 5: Rhabdoid - Unknown function" "Cluster 34: Ciliated cells - Cilia assembly & function" 23 "Nucleoplasm, Mid piece" "Centrosome, Basal body, Cytosol, Principal piece" "HPA039616: , HPA058847: " "unprognostic (1.80e-1)" "unprognostic (5.32e-2)" "unprognostic (2.31e-2)" "unprognostic (4.01e-2)" "unprognostic (1.62e-1)" "unprognostic (2.48e-1)" "unprognostic (1.74e-1)" "unprognostic (2.96e-2)" "unprognostic (6.82e-3)" "unprognostic (3.77e-1)" "potential prognostic favorable (4.10e-7)" "unprognostic (9.11e-3)" "unprognostic (1.30e-1)" "unprognostic (4.44e-2)" "unprognostic (2.17e-1)" "unprognostic (2.21e-1)" "unprognostic (4.92e-1)" "unprognostic (3.89e-2)" "unprognostic (1.06e-1)" "unprognostic (7.57e-2)" "unprognostic (8.73e-3)" "unprognostic (4.45e-2)" "unprognostic (1.30e-2)" "unprognostic (1.16e-1)" "unprognostic (1.11e-2)" "unprognostic (8.02e-2)" "unprognostic (9.32e-2)" "unprognostic (1.88e-1)" "unprognostic (1.06e-1)" "unprognostic (6.92e-2)" "unprognostic (1.21e-1)" WDR26 "FLJ21016, GID7" ENSG00000162923 "WD repeat domain 26" Q9H7D7 1 224385146-224437033 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 880.7;Neutrophils: 1159.1" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 880.7;Neutrophils: 1159.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA028538, HPA028539, HPA061094" Enhanced Enhanced Nucleoplasm,Mitochondria,Cytosol NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 44: Non-specific - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 58 "Nucleoplasm, Cytosol" Mitochondria "HPA028538: , HPA028539: , HPA061094: " "unprognostic (1.18e-1)" "unprognostic (2.39e-2)" "unprognostic (2.22e-1)" "unprognostic (1.23e-2)" "unprognostic (7.97e-2)" "unprognostic (1.00e-1)" "unprognostic (4.05e-2)" "unprognostic (5.31e-2)" "unprognostic (4.23e-1)" "unprognostic (4.17e-2)" "unprognostic (1.40e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-3)" "unprognostic (7.13e-2)" "unprognostic (4.84e-2)" "unprognostic (1.06e-1)" "unprognostic (2.43e-2)" "unprognostic (6.50e-2)" "unprognostic (2.40e-1)" "unprognostic (1.42e-1)" "unprognostic (2.18e-2)" "unprognostic (4.32e-2)" "unprognostic (9.64e-3)" "unprognostic (2.09e-1)" "unprognostic (3.71e-2)" "unprognostic (1.30e-1)" "unprognostic (6.35e-2)" "unprognostic (8.94e-2)" "unprognostic (1.59e-1)" "unprognostic (9.73e-2)" "unprognostic (2.19e-1)" WDR3 "DIP2, FLJ12796, UTP12" ENSG00000065183 "WD repeat domain 3" Q9UNX4 1 117929720-117966543 "Essential proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 74.7;Early primary spermatocytes: 78.0;Parietal cells: 123.8" "Cell type enhanced" "Detected in all" "Gastric glandular cells: 123.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "fallopian tube: 480216.0;intestine: 421989.8;lymphoid tissue: 460910.7;ovary: 1335883.6" "HPA027509, HPA054354, HPA072915" Enhanced Nucleoplasm,Nucleoli No No "Cluster 33: Non-specific - ATP binding" "Cluster 61: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 17: Non-specific - RNA processing" 33 Nucleoli Nucleoplasm "HPA027509: , HPA054354: , HPA072915: " "unprognostic (3.13e-2)" "unprognostic (2.21e-1)" "unprognostic (3.00e-1)" "potential prognostic unfavorable (2.62e-4)" "unprognostic (2.84e-2)" "unprognostic (7.77e-2)" "unprognostic (2.15e-2)" "unprognostic (4.39e-3)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (2.99e-4)" "potential prognostic favorable (4.65e-6)" "unprognostic (1.61e-2)" "unprognostic (2.65e-2)" "potential prognostic unfavorable (3.93e-4)" "unprognostic (6.58e-3)" "unprognostic (2.54e-3)" "potential prognostic unfavorable (3.62e-4)" "unprognostic (2.31e-1)" "unprognostic (6.55e-2)" "unprognostic (1.50e-1)" "unprognostic (3.69e-1)" "potential prognostic unfavorable (8.81e-4)" "unprognostic (2.02e-2)" "unprognostic (1.69e-2)" "potential prognostic favorable (1.73e-4)" "unprognostic (5.28e-2)" "unprognostic (2.45e-2)" "unprognostic (1.16e-1)" "unprognostic (2.15e-1)" "unprognostic (9.87e-3)" "unprognostic (1.79e-1)" WDR37 KIAA0982 ENSG00000047056 "WD repeat domain 37" Q9Y2I8 10 1049538-1160991 "Disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 373.2" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 373.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglia and Neuropil: 57975221.1" "Tissue enhanced" "Detected in many" "cerebral cortex: 77449110.3" "HPA037376, HPA037565" Enhanced Approved "Intermediate filaments" No No "Cluster 15: NK-cells - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 52: Non-specific - Mitochondria" "Cluster 55: Myocytes - Oxidative muscle function" 11 "Intermediate filaments" "HPA037376: , HPA037565: " "unprognostic (1.29e-1)" "unprognostic (3.04e-2)" "unprognostic (3.88e-2)" "unprognostic (3.81e-2)" "unprognostic (5.82e-2)" "unprognostic (2.12e-1)" "unprognostic (3.19e-1)" "potential prognostic favorable (1.27e-5)" "potential prognostic favorable (2.10e-4)" "unprognostic (3.03e-1)" "potential prognostic favorable (4.34e-4)" "unprognostic (1.85e-2)" "potential prognostic favorable (1.72e-4)" "potential prognostic unfavorable (7.64e-4)" "unprognostic (2.47e-1)" "unprognostic (2.12e-2)" "unprognostic (2.30e-1)" "unprognostic (2.53e-1)" "unprognostic (3.04e-1)" "unprognostic (5.65e-2)" "unprognostic (2.36e-2)" "potential prognostic favorable (1.59e-4)" "unprognostic (8.78e-2)" "unprognostic (2.99e-1)" "unprognostic (8.77e-3)" "unprognostic (1.66e-1)" "unprognostic (2.46e-1)" "unprognostic (8.90e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (5.48e-7)" "unprognostic (1.86e-1)" WDR47 KIAA0893 ENSG00000085433 "WD repeat domain 47" O94967 1 108970214-109042113 "Predicted intracellular proteins, Transporters" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 41.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 219.4;Rod photoreceptor cells: 129.2" "Cell type enhanced" "Detected in all" "Neuronal cells: 219.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Skin - Keratinocyte (other), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Astrocytes and Neuropil: 6263558.7;Microglia and Neuropil: 11378857.6;Neurons: 5921626.0" "Group enriched" "Detected in many" "cerebral cortex: 23539363.2;pancreas: 10810714.3" "HPA027287, HPA027289" Approved Approved "Actin filaments,Primary cilium" NA NA "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 37: Non-specific - mRNA processing" "Cluster 20: Non-specific - Transcription regulation" 4 "Actin filaments, Primary cilium" "HPA027287: , HPA027289: " "unprognostic (1.86e-2)" "unprognostic (7.54e-2)" "unprognostic (1.28e-1)" "unprognostic (3.23e-1)" "unprognostic (3.31e-1)" "unprognostic (7.78e-3)" "unprognostic (3.14e-1)" "unprognostic (9.09e-3)" "potential prognostic favorable (7.69e-4)" "unprognostic (2.11e-3)" "validated prognostic favorable (3.75e-6)" "validated prognostic favorable (6.49e-4)" "unprognostic (8.91e-2)" "unprognostic (9.75e-3)" "unprognostic (1.55e-1)" "unprognostic (1.20e-2)" "unprognostic (4.72e-3)" "unprognostic (1.80e-2)" "unprognostic (1.04e-1)" "unprognostic (2.09e-2)" "unprognostic (7.72e-2)" "unprognostic (5.21e-2)" "unprognostic (2.10e-1)" "unprognostic (1.32e-1)" "unprognostic (3.12e-2)" "unprognostic (2.19e-2)" "unprognostic (1.61e-1)" "unprognostic (5.74e-2)" "unprognostic (3.81e-2)" "unprognostic (1.06e-2)" "unprognostic (4.92e-2)" WDR49 FLJ33620 ENSG00000174776 "WD repeat domain 49" Q8IV35 3 167478684-167653983 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 8.8;fallopian tube: 8.5;intestine: 4.2" "Cell type enhanced" "Detected in many" "Astrocytes: 304.6;Bergmann glia: 618.4;Choroid plexus epithelial cells: 747.4;Endometrial ciliated cells: 463.8;Ependymal cells: 1533.8;Epididymal efferent duct ciliated cells: 226.6;Fallopian tube ciliated cells: 355.0;Podocytes: 405.5;Respiratory ciliated cells: 1021.4;Respiratory deuterosomal cells: 269.5" "Group enriched" "Detected in many" 5 "Ciliated cells: 1533.8;Glial cells: 618.4;Renal nephron cells: 405.5" "Group enriched" "Detected in all" 48 "astrocyte: 615.9;Bergmann glia: 657.4;choroid plexus epithelial cell: 560.5;ependymal cell: 1727.6" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "classical monocyte: 2.7;myeloid DC: 2.2;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 24 "dendritic cells: 2.9;monocytes: 2.7" "Cancer enriched" "Detected in single" 7 "Leukemia: 2.1" "Kidney - Podocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Region enhanced" "Detected in many" "midbrain: 12.1" "Cell type enriched" "Detected in single" 297 "Collecting ducts: 29746.6" "Not detected" "Not detected" "HPA036225, HPA036226" Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitotic spindle,Primary cilium,Primary cilium tip,Primary cilium transition zone,Basal body,Cytosol" Yes NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 14: Myeloid leukemia - Innate immune response" "Cluster 34: Ciliated cells - Cilia assembly & function" 1 "Nucleoplasm, Nuclear bodies" "Mitotic spindle, Primary cilium, Primary cilium tip, Primary cilium transition zone, Basal body, Cytosol" "HPA036225: , HPA036226: " "unprognostic (1.63e-1)" "unprognostic (1.72e-3)" "unprognostic (3.20e-1)" "unprognostic (9.21e-3)" "unprognostic (1.29e-2)" "unprognostic (1.18e-1)" "unprognostic (2.12e-1)" "unprognostic (1.96e-1)" "unprognostic (1.78e-2)" "unprognostic (2.63e-3)" "unprognostic (2.97e-1)" WDR54 FLJ12953 ENSG00000005448 "WD repeat domain 54" Q9H977 2 74421678-74425755 "Predicted intracellular proteins" Fertilization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 66.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 212.6;Epididymal efferent duct ciliated cells: 262.7;Fallopian tube ciliated cells: 496.9;Late primary spermatocytes: 195.0;Late spermatids: 189.1;Respiratory ciliated cells: 452.2" "Group enriched" "Detected in many" 6 "Ciliated cells: 496.9;Spermatogenic cell types: 195.0" "Cell type enhanced" "Detected in all" "ependymal cell: 54.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Liver - Vascular endothelial cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in many" "Fallopian tube cells: 21792110.0" "Tissue enhanced" "Detected in many" "fallopian tube: 3416190.9" "HPA043257, HPA053558" Enhanced Approved "Nucleoli,Golgi apparatus,Vesicles,Primary cilium tip,Centriolar satellite,Cytosol,Acrosome,Flagellar centriole,Mid piece,Principal piece" NA NA "Cluster 13: Non-specific - Mitochondria" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 23: Choroid plexus - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 107: Ciliated cells - Cilia assembly & function" 4 "Golgi apparatus, Vesicles, Acrosome" "Nucleoli, Primary cilium tip, Centriolar satellite, Cytosol, Flagellar centriole, Mid piece, Principal piece" "HPA043257: , HPA053558: " "potential prognostic unfavorable (2.27e-4)" "unprognostic (4.49e-2)" "unprognostic (1.96e-1)" "unprognostic (9.22e-2)" "unprognostic (4.28e-1)" "unprognostic (9.17e-2)" "unprognostic (4.43e-2)" "unprognostic (1.49e-1)" "unprognostic (1.01e-3)" "unprognostic (1.56e-1)" "potential prognostic favorable (1.52e-5)" "unprognostic (2.29e-2)" "unprognostic (3.19e-2)" "unprognostic (2.28e-2)" "unprognostic (7.44e-2)" "unprognostic (2.86e-1)" "unprognostic (4.97e-2)" "unprognostic (5.44e-2)" "unprognostic (1.83e-1)" "unprognostic (2.34e-2)" "unprognostic (1.35e-1)" "unprognostic (1.77e-3)" "unprognostic (8.74e-2)" "unprognostic (7.37e-2)" "unprognostic (4.27e-2)" "unprognostic (9.78e-2)" "unprognostic (2.61e-2)" "unprognostic (7.27e-2)" "unprognostic (4.99e-1)" "unprognostic (2.46e-1)" "unprognostic (2.49e-2)" WDR55 "FLJ20195, FLJ21702" ENSG00000120314 "WD repeat domain 55" Q9H6Y2 5 140664868-140674124 "Essential proteins, Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 76.1" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 76.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "T-cells: 1220475.7" "Tissue enhanced" "Detected in many" "intestine: 1374686.9" "HPA043470, HPA048143, HPA075133" Uncertain Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 49: Non-specific - Transcription" "Cluster 44: Non-specific - Mixed function" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 20: Non-specific - Transcription regulation" 9 Nucleoplasm Nucleoli "HPA043470: , HPA048143: , HPA075133: " "unprognostic (3.99e-2)" "unprognostic (1.63e-3)" "unprognostic (4.18e-1)" "unprognostic (2.28e-3)" "unprognostic (1.04e-1)" "unprognostic (1.53e-1)" "unprognostic (9.09e-3)" "unprognostic (1.54e-1)" "unprognostic (2.70e-2)" "unprognostic (1.11e-3)" "unprognostic (1.01e-2)" "unprognostic (1.96e-1)" "unprognostic (2.97e-2)" "potential prognostic unfavorable (1.25e-5)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (2.15e-2)" "unprognostic (6.03e-3)" "unprognostic (1.50e-1)" "unprognostic (1.27e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (2.78e-1)" "unprognostic (6.44e-2)" "unprognostic (2.80e-1)" "unprognostic (7.06e-3)" "unprognostic (6.39e-2)" "unprognostic (1.65e-1)" "unprognostic (1.45e-1)" "unprognostic (3.41e-2)" "unprognostic (1.86e-1)" WDR62 "C19orf14, DKFZP434J046, FLJ33298, MCPH2" ENSG00000075702 "WD repeat domain 62" O43379 19 36054649-36105108 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Intellectual disability, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 103.4;testis: 66.9;tongue: 58.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 124.2;Differentiating spermatogonia: 40.1;Early primary spermatocytes: 107.3;Early spermatids: 35.8;Late primary spermatocytes: 76.9;Late spermatids: 64.9;Monocyte progenitors: 35.1;Rod photoreceptor cells: 89.6" "Cell type enhanced" "Detected in many" "Neuronal cells: 124.2;Spermatogenic cell types: 107.3" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 24.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.7" "Lineage enriched" "Detected in single" 4 "monocytes: 2.7" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Heart muscle - Cardiomyocytes, Lung - Mitotic cells (Lung), Skeletal muscle - Skeletal myocytes, Skeletal muscle - Skeletal myocytes, Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 439 "Granulosa cells: 43851.2" "Tissue enriched" "Detected in single" 73 "bone marrow: 7277.0" "HPA043255, HPA043639" Enhanced Approved "Centriolar satellite,Cytosol" NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 62: Skeletal muscle - Muscle contraction" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 27: Non-specific - Cell proliferation" 49 Cytosol "Centriolar satellite" "HPA043255: , HPA043639: " "unprognostic (1.11e-1)" "unprognostic (5.22e-1)" "unprognostic (1.36e-1)" "unprognostic (5.83e-3)" "unprognostic (3.84e-2)" "unprognostic (1.59e-1)" "unprognostic (3.06e-1)" "unprognostic (1.99e-2)" "unprognostic (9.87e-3)" "potential prognostic unfavorable (2.99e-5)" "unprognostic (3.27e-3)" "validated prognostic unfavorable (1.43e-6)" "validated prognostic unfavorable (1.80e-4)" "unprognostic (4.06e-3)" "unprognostic (4.21e-2)" "potential prognostic favorable (7.94e-4)" "unprognostic (3.58e-2)" "unprognostic (4.24e-2)" "unprognostic (2.83e-2)" "unprognostic (4.79e-2)" "unprognostic (3.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.54e-2)" "unprognostic (1.60e-1)" "unprognostic (2.00e-1)" "unprognostic (4.59e-3)" "unprognostic (1.67e-1)" "unprognostic (1.40e-1)" WDR74 "FLJ10439, Nsa1" ENSG00000133316 "WD repeat domain 74" Q6RFH5 11 62832342-62841809 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 119.2" "Cell type enhanced" "Detected in many" "Gastric chief cells: 161.6;Innate lymphoid cells: 131.7;Mucous neck cells: 147.0;pDCs: 135.9;Plasma cells: 199.1" "Cell type enhanced" "Detected in all" "Plasma cells: 199.1" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Uterine Corpus Endometrial Carcinoma (TCGA): 886.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oocytes: 3685316.4" "Group enriched" "Detected in some" "lymphoid tissue: 730232.4;ovary: 834685.3" "HPA037795, HPA038419" Uncertain Supported Nucleoplasm,Nucleoli NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 41: Non-specific - Nucleosome assembly" "Cluster 20: Non-specific - Transcription regulation" 6 "Nucleoplasm, Nucleoli" "HPA037795: , HPA038419: " "potential prognostic unfavorable (2.71e-4)" "unprognostic (1.49e-1)" "unprognostic (1.81e-1)" "unprognostic (2.22e-1)" "unprognostic (1.44e-1)" "unprognostic (1.12e-1)" "unprognostic (3.56e-1)" "potential prognostic favorable (7.50e-4)" "potential prognostic unfavorable (3.91e-4)" "unprognostic (2.01e-1)" "unprognostic (7.56e-2)" "unprognostic (3.07e-3)" "unprognostic (8.32e-2)" "potential prognostic unfavorable (3.46e-4)" "unprognostic (7.57e-3)" "unprognostic (6.88e-3)" "potential prognostic unfavorable (6.55e-4)" "unprognostic (1.60e-1)" "unprognostic (1.35e-1)" "unprognostic (4.13e-2)" "unprognostic (4.70e-1)" "potential prognostic unfavorable (7.28e-4)" "unprognostic (1.57e-2)" "unprognostic (1.28e-1)" "unprognostic (2.57e-2)" "potential prognostic favorable (6.72e-4)" "unprognostic (6.05e-3)" "unprognostic (1.97e-1)" "unprognostic (1.71e-1)" "unprognostic (9.51e-2)" "unprognostic (4.43e-2)" WDR81 "CAMRQ2, FLJ33817, PPP1R166, SORF-2" ENSG00000167716 "WD repeat domain 81" Q562E7 17 1716523-1738599 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 28.6;Hepatocytes: 22.1;Kupffer cells: 20.5;Microglia: 30.8;Proximal tubule cells: 25.3" "Cell type enhanced" "Detected in many" "Glial cells: 30.8;Reproductive supporting cells: 28.6" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Heart muscle - Macrophages, Lung - Macrophages" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in many" "lymphoid tissue: 28474718.2" "HPA023044, HPA063703" Uncertain Approved Nucleoplasm,Vesicles,Cytosol NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 70: Non-specific - Protein processing" "Cluster 27: Non-specific - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 3 Nucleoplasm "Vesicles, Cytosol" "HPA023044: , HPA063703: " "unprognostic (2.57e-1)" "unprognostic (2.23e-1)" "unprognostic (1.37e-2)" "unprognostic (9.28e-3)" "unprognostic (5.53e-2)" "unprognostic (1.37e-1)" "unprognostic (8.74e-2)" "unprognostic (2.84e-1)" "unprognostic (5.24e-3)" "unprognostic (1.17e-2)" "unprognostic (4.20e-1)" "unprognostic (4.35e-2)" "unprognostic (2.12e-3)" "unprognostic (9.73e-2)" "unprognostic (3.00e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (1.10e-1)" "unprognostic (1.35e-1)" "unprognostic (2.64e-2)" "unprognostic (3.76e-1)" "unprognostic (2.28e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-1)" "unprognostic (4.38e-1)" "unprognostic (3.89e-2)" "unprognostic (9.80e-2)" "unprognostic (2.11e-1)" "unprognostic (2.67e-2)" "unprognostic (5.59e-2)" "potential prognostic favorable (7.54e-4)" WDR83 MORG1 ENSG00000123154 "WD repeat domain 83" Q9BRX9 19 12666802-12675832 "Essential proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 85.7;Epicardial cells: 88.7;Late spermatids: 113.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 88.7;Myocytes: 85.7;Spermatogenic cell types: 113.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Collecting ducts: 96883.9;Distal tubules: 128782.9;T-cells: 69740.0" "Group enriched" "Detected in some" "lymphoid tissue: 670249.6;salivary gland: 648041.6" "HPA042629, HPA042838" Uncertain Approved "Nucleoplasm,Vesicles,Centriolar satellite,Basal body,Cytosol" NA NA "Cluster 44: Plasmacytoid DCs - Plasma membrane proteins" "Cluster 64: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 90 "Nucleoplasm, Vesicles" "Centriolar satellite, Basal body, Cytosol" "HPA042629: , HPA042838: " "unprognostic (6.40e-2)" "unprognostic (1.36e-1)" "unprognostic (5.33e-2)" "unprognostic (3.09e-2)" "unprognostic (1.46e-2)" "unprognostic (1.52e-1)" "unprognostic (1.33e-1)" "unprognostic (7.97e-3)" "unprognostic (2.29e-1)" "unprognostic (3.33e-3)" "potential prognostic favorable (2.20e-7)" "unprognostic (4.11e-3)" "unprognostic (3.13e-2)" "unprognostic (2.75e-1)" "unprognostic (1.26e-2)" "unprognostic (1.13e-2)" "unprognostic (2.65e-1)" "unprognostic (3.34e-1)" "unprognostic (8.54e-2)" "unprognostic (3.89e-2)" "unprognostic (3.11e-1)" "unprognostic (3.31e-2)" "unprognostic (7.75e-2)" "unprognostic (2.10e-2)" "unprognostic (1.89e-1)" "unprognostic (6.30e-2)" "unprognostic (5.84e-2)" "unprognostic (4.03e-2)" "unprognostic (3.37e-1)" "unprognostic (2.87e-1)" "unprognostic (5.82e-2)" WDR86 ENSG00000187260 "WD repeat domain 86" Q86TI4 7 151375909-151410727 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "thyroid gland: 27.6" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 32.7;Decidual stromal cells: 54.0;Endometrial stromal cells: 43.3;Ependymal cells: 70.9;Epididymal efferent duct ciliated cells: 42.8;Fallopian tube ciliated cells: 49.8;Fibro-adipogenic progenitors: 41.0;Fibroblasts: 35.9;Innate lymphoid cells: 39.5;Müller glia: 37.8;Pituicytes/FSCs: 57.3;Respiratory ciliated cells: 36.3" "Cell type enhanced" "Detected in many" "Ciliated cells: 70.9;Glial cells: 57.3;Stromal cells: 54.0" "Cell type enhanced" "Detected in many" "ependymal cell: 69.6;fibroblast: 181.8" "Cancer enhanced" "Detected in many" "Thyroid Carcinoma (TCGA): 35.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Neuroblastoma: 10.4;testis cancer: 3.5" "Colon - Enteric glia cells, Stomach - Chief cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 357 "Fallopian tube cells: 35736.3" "Not detected" "Not detected" HPA021086 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 64: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 108: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane, Cytosol" "HPA021086: " "unprognostic (2.04e-1)" "unprognostic (3.62e-2)" "unprognostic (1.23e-1)" "unprognostic (1.08e-2)" "unprognostic (9.53e-2)" "unprognostic (1.42e-3)" "unprognostic (1.10e-1)" "unprognostic (2.42e-1)" "unprognostic (5.50e-2)" "unprognostic (3.76e-3)" "unprognostic (2.34e-1)" "unprognostic (2.66e-2)" "unprognostic (6.41e-2)" "unprognostic (4.32e-2)" "unprognostic (7.81e-2)" "unprognostic (1.12e-1)" "unprognostic (3.03e-2)" "unprognostic (7.22e-2)" "unprognostic (2.04e-1)" "unprognostic (7.70e-2)" "unprognostic (3.57e-1)" WEE1 WEE1A ENSG00000166483 "WEE1 G2 checkpoint kinase" P30291 11 9573670-9593457 "Cancer-related genes, Enzymes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 257.6;Breast secretory cells: 258.2;Endometrial glandular cells: 345.2;Endometrial luminal cells: 264.0;Extravillous trophoblasts: 278.8;Ocular epithelial cells: 344.4;Urothelial cells: 299.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 344.4;Glandular cells: 345.2" "Cell type enhanced" "Detected in many" "ependymal cell: 18.5;fibroblast: 18.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Granulosa cells: 1445764.4" "Tissue enriched" "Detected in single" 725 "lymphoid tissue: 72493.9" "CAB004619, HPA068845" Approved Supported Nucleoli No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 58: Skin - Keratinization" "Cluster 44: Non-specific - Mixed function" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 100: Stratified epithelial cells - Barrier functions" 41 Nucleoli "CAB004619: , HPA068845: " "unprognostic (8.29e-2)" "unprognostic (2.13e-1)" "unprognostic (1.53e-1)" "unprognostic (7.53e-3)" "unprognostic (5.89e-2)" "unprognostic (5.63e-3)" "unprognostic (1.27e-1)" "unprognostic (1.86e-1)" "unprognostic (1.78e-2)" "unprognostic (2.67e-1)" "unprognostic (1.74e-3)" "unprognostic (2.14e-1)" "unprognostic (5.80e-2)" "unprognostic (5.51e-3)" "unprognostic (1.16e-2)" "unprognostic (2.67e-2)" "unprognostic (3.69e-2)" "unprognostic (2.64e-1)" "unprognostic (2.47e-2)" "unprognostic (5.70e-3)" "unprognostic (1.42e-1)" "unprognostic (1.22e-2)" "potential prognostic unfavorable (7.67e-4)" "unprognostic (1.22e-1)" "unprognostic (4.23e-2)" "unprognostic (1.17e-2)" "unprognostic (6.28e-2)" "unprognostic (9.04e-2)" "unprognostic (5.12e-1)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" WEE2 "FLJ16107, WEE1B" ENSG00000214102 "WEE2 oocyte meiosis inhibiting kinase" P0C1S8 7 141708353-141731271 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Meiosis "Kinase, Transferase, Tyrosine-protein kinase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 6 "Oocytes: 9.2" "Cell type enriched" "Detected in some" 6 "Oocytes: 9.2" "Cell type enhanced" "Detected in some" "Bergmann glia: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" "Proximal tubules: 58172.2" "Not detected" "Not detected" "HPA027418, HPA054280" Uncertain Supported Nucleoplasm NA NA "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 28: Astrocytes - Homeostasis & neuron support" Nucleoplasm "HPA027418: , HPA054280: " WIPF1 "WASPIP, WIP" ENSG00000115935 "WAS/WASL interacting protein family member 1" O43516 2 174559572-174682916 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 107.0" "Cell type enhanced" "Detected in many" "B-cells: 338.5;Microglia: 323.4;monocytes: 357.4;Neutrophil progenitors: 473.6;Neutrophils: 1271.5;NK-cells: 493.1;Platelets: 898.7;T-cells: 468.9" "Cell type enhanced" "Detected in many" "Neutrophils: 1271.5;Platelets: 898.7" "Cell type enhanced" "Detected in all" "central nervous system macrophage: 424.4;committed oligodendrocyte precursor: 436.2;leukocyte: 563.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "lymphoma: 125.3;Myeloma: 104.8" "Breast - Fibroblasts, Colon - Enteric glia cells, Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "B-cells: 23158110.8;Macrophages: 16922457.6;T-cells: 26414051.6" "Tissue enriched" "Detected in many" "lymphoid tissue: 31965268.8" "HPA003739, CAB009737, HPA070706" Enhanced Approved "Plasma membrane,Cytosol" No No 460000 "Cluster 35: Neutrophils - Protein binding" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 30: White matter - Myelination" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 24: Neutrophils - Innate immunity signal integration" 26 Cytosol "Plasma membrane" "CAB009737: , HPA003739: , HPA070706: " "unprognostic (1.47e-2)" "unprognostic (3.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.82e-1)" "unprognostic (6.49e-2)" "unprognostic (2.26e-1)" "unprognostic (3.10e-1)" "unprognostic (3.08e-1)" "unprognostic (3.80e-3)" "unprognostic (1.97e-3)" "unprognostic (6.50e-3)" "unprognostic (1.02e-1)" "unprognostic (5.65e-2)" "unprognostic (1.71e-1)" "unprognostic (8.64e-2)" "unprognostic (4.29e-2)" "unprognostic (6.25e-2)" "unprognostic (2.39e-1)" "unprognostic (4.10e-2)" "unprognostic (2.38e-2)" "unprognostic (1.13e-2)" "unprognostic (1.10e-1)" "unprognostic (5.38e-2)" "unprognostic (1.75e-1)" "unprognostic (4.56e-1)" "unprognostic (1.90e-1)" "unprognostic (5.19e-2)" "unprognostic (3.72e-2)" "unprognostic (6.97e-2)" "unprognostic (4.87e-1)" "unprognostic (5.59e-2)" WIPI1 "ATG18, ATG18A, FLJ10055, WIPI49" ENSG00000070540 "WD repeat domain, phosphoinositide interacting 1" Q5MNZ9 17 68420948-68457513 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 119.2" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 294.7;Platelets: 211.7;Respiratory secretory cells: 203.6;Syncytiotrophoblasts: 223.7" "Cell type enhanced" "Detected in all" "Trophoblast cells: 294.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "basophil: 114.9;eosinophil: 224.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 224.2" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "bone marrow: 9970568.1;heart muscle: 2503121.8;lung: 9045168.7" "HPA007493, CAB037230" Enhanced Supported "Nucleoplasm,Golgi apparatus,Cytosol" NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 48: Neutrophils - Phagocytosis & degranulation" "Golgi apparatus" "Nucleoplasm, Cytosol" "CAB037230: , HPA007493: " "unprognostic (2.71e-1)" "unprognostic (1.18e-1)" "unprognostic (6.95e-2)" "unprognostic (2.26e-1)" "unprognostic (2.47e-2)" "unprognostic (1.00e-1)" "unprognostic (2.19e-2)" "potential prognostic unfavorable (4.90e-4)" "unprognostic (7.98e-2)" "unprognostic (2.16e-3)" "unprognostic (8.40e-2)" "unprognostic (4.50e-2)" "potential prognostic favorable (3.69e-4)" "unprognostic (3.10e-3)" "unprognostic (5.60e-3)" "unprognostic (3.41e-1)" "unprognostic (3.27e-2)" "unprognostic (9.55e-2)" "unprognostic (1.38e-1)" "unprognostic (2.65e-1)" "unprognostic (7.09e-2)" "unprognostic (1.05e-1)" "unprognostic (2.53e-1)" "unprognostic (3.73e-1)" "unprognostic (1.37e-1)" "unprognostic (1.15e-1)" "unprognostic (3.64e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" "unprognostic (4.90e-2)" "unprognostic (1.43e-1)" WLS "C1orf139, EVI, FLJ23091, GPR177, mig-14, MRP" ENSG00000116729 "Wnt ligand secretion mediator" Q5T9L3 1 68098473-68233120 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial luminal cells: 551.5;Ependymal cells: 405.5;Neutrophils: 375.8" "Cell type enhanced" "Detected in many" "Luminal cells: 551.5" "Cell type enhanced" "Detected in all" "ependymal cell: 529.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 22.1;neutrophil: 62.1" "Group enriched" "Detected in many" 46 "granulocytes: 62.1;monocytes: 22.1" "Cancer enhanced" "Detected in many" "testis cancer: 329.0" "Breast - Breast myoepithelial cells, Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreas epithelial cells: 3124434.7" "Group enriched" "Detected in many" "salivary gland: 2435946.3;Stomach: 694932.7" HPA069520 Approved Approved "Endoplasmic reticulum,Cytosol" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 14 "Endoplasmic reticulum, Cytosol" "HPA069520: " "unprognostic (7.89e-2)" "unprognostic (9.55e-3)" "unprognostic (8.03e-2)" "unprognostic (1.60e-2)" "unprognostic (9.56e-3)" "unprognostic (9.18e-2)" "unprognostic (4.51e-2)" "unprognostic (3.94e-2)" "unprognostic (8.90e-3)" "unprognostic (3.99e-1)" "potential prognostic favorable (3.21e-11)" "unprognostic (3.99e-3)" "unprognostic (8.41e-2)" "unprognostic (6.74e-3)" "unprognostic (1.61e-2)" "unprognostic (4.47e-2)" "unprognostic (1.06e-2)" "unprognostic (5.80e-2)" "unprognostic (7.34e-2)" "unprognostic (2.95e-2)" "unprognostic (3.66e-2)" "unprognostic (5.71e-2)" "unprognostic (4.43e-2)" "unprognostic (1.53e-1)" "unprognostic (1.12e-1)" "unprognostic (2.89e-2)" "unprognostic (3.23e-2)" "unprognostic (2.58e-2)" "unprognostic (1.22e-1)" "unprognostic (1.51e-2)" "unprognostic (1.89e-1)" WNK1 "HSAN2, HSN2, PPP1R167, PRKWNK1" ENSG00000060237 "WNK lysine deficient protein kinase 1" Q9H4A3 12 752579-911452 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal convoluted tubule cells: 1795.8;Esophageal apical cells: 826.4;Renal connecting tubule cells: 892.9" "Cell type enhanced" "Detected in all" "Renal nephron cells: 1795.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Kidney - Intercalated cells, Lung - Alveolar cells type 1, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in many" "HPA046541, HPA059157" Enhanced Supported Cytosol NA NA 22000 "Cluster 38: Monocytes & Neutrophils - Degranulation" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 6: Non-specific - Immune response" "Cluster 38: Non-specific - Transcription" "Cluster 50: Renal epithelial cells - Ion transport and pH regulation" 55 Cytosol "HPA046541: , HPA059157: " "unprognostic (1.40e-1)" "unprognostic (3.82e-2)" "unprognostic (2.25e-1)" "unprognostic (4.49e-2)" "unprognostic (1.94e-1)" "unprognostic (7.01e-3)" "unprognostic (7.05e-2)" "unprognostic (2.82e-1)" "unprognostic (6.52e-2)" "unprognostic (3.06e-2)" "unprognostic (3.70e-3)" "unprognostic (1.22e-1)" "unprognostic (1.13e-1)" "potential prognostic unfavorable (6.78e-4)" "unprognostic (3.23e-3)" "unprognostic (2.29e-2)" "unprognostic (1.40e-1)" "unprognostic (1.36e-1)" "unprognostic (1.34e-2)" "unprognostic (4.55e-3)" "unprognostic (8.02e-2)" "unprognostic (1.56e-1)" "unprognostic (2.43e-3)" "unprognostic (1.28e-1)" "unprognostic (6.98e-2)" "unprognostic (1.01e-3)" "unprognostic (9.40e-2)" "unprognostic (1.20e-1)" "unprognostic (1.10e-1)" "unprognostic (9.03e-2)" "unprognostic (2.83e-1)" WNT5A hWNT5A ENSG00000114251 "Wnt family member 5A" P41221 3 55465715-55490539 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Chondrogenesis, Differentiation, Wnt signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 25.7;salivary gland: 32.4" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 114.3;Esophageal apical cells: 90.6;Papillary tip epithelial cells: 117.8;Pituitary stem cells: 97.5;Prostatic club cells: 206.1;Prostatic hillock cells: 141.1;Salivary acinar cells: 80.9;Transitional alveolar cells: 59.5;Urothelial cells: 54.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 141.1;Glandular cells: 206.1;Renal nephron cells: 117.8;Stromal cells: 114.3" "Cell type enhanced" "Detected in many" "Bergmann glia: 54.8;central nervous system macrophage: 49.4;fibroblast: 72.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Brain cancer: 91.1" "Kidney - Fibroblasts, Liver - Hepatocytes, Pituitary gland - Undifferentiated cells (Pituitary gland)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 70530 "ovary: 7052992.3" HPA072252 Uncertain "Nucleoli fibrillar center,Microtubules,Mitotic spindle,Primary cilium" "Secreted to extracellular matrix" "Developmental protein" Yes NA "Cluster 11: Esophagus - Basic cellular processes" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 108: Fibroblasts - ECM organization" 3 "Microtubules, Mitotic spindle, Primary cilium" "Nucleoli fibrillar center" "HPA072252: " "unprognostic (1.29e-1)" "unprognostic (3.73e-3)" "unprognostic (3.15e-1)" "unprognostic (1.40e-1)" "potential prognostic favorable (5.93e-4)" "unprognostic (1.46e-1)" "unprognostic (4.81e-2)" "unprognostic (5.65e-2)" "unprognostic (5.86e-2)" "unprognostic (1.63e-1)" "unprognostic (1.39e-3)" "unprognostic (3.33e-2)" "unprognostic (9.62e-3)" "unprognostic (2.26e-2)" "unprognostic (2.93e-1)" "unprognostic (4.48e-1)" "unprognostic (1.87e-1)" "unprognostic (1.95e-2)" "unprognostic (2.41e-2)" "unprognostic (1.40e-1)" "unprognostic (8.71e-2)" "unprognostic (4.07e-3)" "unprognostic (1.75e-1)" "unprognostic (9.07e-2)" "unprognostic (7.26e-2)" "unprognostic (2.82e-1)" "unprognostic (5.45e-2)" "unprognostic (4.38e-2)" "unprognostic (2.10e-1)" "unprognostic (2.36e-2)" "unprognostic (2.28e-1)" WRNIP1 "bA420G6.2, CFAP93, FAP93, FLJ22526, WHIP" ENSG00000124535 "WRN helicase interacting protein 1" Q96S55 6 2765393-2786952 "Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication, Immunity, Innate immunity" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Platelets: 190.3" "Cell type enhanced" "Detected in many" "Platelets: 190.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 58396689.4" "Low tissue specificity" "Detected in many" "HPA031752, HPA031753" Enhanced Approved Nucleoplasm No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 17: Non-specific - RNA processing" 28 Nucleoplasm "HPA031752: , HPA031753: " "unprognostic (3.85e-2)" "unprognostic (4.02e-2)" "unprognostic (2.07e-2)" "unprognostic (3.76e-1)" "unprognostic (1.56e-1)" "unprognostic (1.37e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-2)" "unprognostic (4.70e-2)" "unprognostic (7.30e-3)" "unprognostic (2.63e-3)" "unprognostic (4.73e-3)" "unprognostic (3.94e-2)" "validated prognostic unfavorable (6.40e-4)" "validated prognostic unfavorable (3.85e-4)" "unprognostic (2.75e-1)" "unprognostic (8.58e-2)" "unprognostic (1.33e-2)" "unprognostic (8.56e-2)" "unprognostic (3.39e-2)" "unprognostic (8.45e-2)" "unprognostic (2.79e-1)" "unprognostic (1.27e-1)" "unprognostic (1.90e-1)" "unprognostic (7.85e-2)" "unprognostic (2.49e-1)" "unprognostic (5.66e-2)" "unprognostic (6.43e-2)" "unprognostic (2.89e-1)" "unprognostic (8.83e-2)" "unprognostic (3.87e-2)" WWC2 "BOMB, FLJ22029" ENSG00000151718 "WW and C2 domain containing 2" Q6AWC2 4 183099257-183320777 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 638.7;Loop of henle epithelial cells: 359.5;Mesothelial cells: 338.4;Rod photoreceptor cells: 384.8" "Cell type enhanced" "Detected in all" "Alveolar cells: 638.7" "Cell type enhanced" "Detected in all" "endothelial cell: 527.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Liver - Hepatocytes, Lung - Alveolar cells type 1, Skin - Endothelial cells, Spleen - Endothelial cells, Testis - Spermatocytes, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 1191650.5" "Tissue enriched" "Detected in single" 165911 "lung: 16591149.5" HPA044005 Uncertain Approved Microtubules NA NA "Cluster 42: Retina - Visual perception" "Cluster 8: Immune cells - Immune response" "Cluster 15: Kidney cancer - Membrane components" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 27 Microtubules "HPA044005: " "unprognostic (1.32e-1)" "unprognostic (1.91e-1)" "unprognostic (2.88e-2)" "unprognostic (1.60e-2)" "unprognostic (1.06e-1)" "unprognostic (2.01e-2)" "unprognostic (9.07e-2)" "unprognostic (2.27e-1)" "unprognostic (4.75e-3)" "unprognostic (2.24e-2)" "validated prognostic favorable (2.11e-9)" "validated prognostic favorable (6.87e-5)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.53e-1)" "unprognostic (5.65e-2)" "unprognostic (7.50e-2)" "unprognostic (5.22e-1)" "unprognostic (5.16e-2)" "unprognostic (7.11e-3)" "unprognostic (2.25e-2)" "potential prognostic unfavorable (9.52e-4)" "unprognostic (5.97e-2)" "unprognostic (1.49e-1)" "unprognostic (2.91e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.10e-1)" "unprognostic (1.10e-2)" WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342547-86478420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 160.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 477.6" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 1880920.7;T-cells: 1158041.0" "Group enriched" "Detected in some" 1697 "cerebral cortex: 83129.1;liver: 196740.7;lymphoid tissue: 229148.6" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 72: Macrophages - Phagocytosis & lysosomal degradation" 64 Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: " "unprognostic (9.17e-2)" "unprognostic (1.47e-1)" "unprognostic (2.24e-2)" "unprognostic (1.11e-2)" "unprognostic (6.03e-2)" "unprognostic (1.55e-1)" "unprognostic (4.51e-2)" "unprognostic (1.37e-1)" "unprognostic (1.80e-1)" "unprognostic (2.62e-2)" "validated prognostic favorable (1.71e-6)" "validated prognostic favorable (5.51e-4)" "unprognostic (2.48e-2)" "unprognostic (1.00e-1)" "unprognostic (6.58e-2)" "unprognostic (9.99e-2)" "unprognostic (3.68e-1)" "unprognostic (1.07e-1)" "unprognostic (3.46e-1)" "potential prognostic unfavorable (3.08e-5)" "unprognostic (4.54e-3)" "potential prognostic unfavorable (1.86e-4)" "unprognostic (2.50e-2)" "unprognostic (9.01e-2)" "unprognostic (6.04e-2)" "unprognostic (1.48e-1)" "unprognostic (1.13e-1)" "unprognostic (2.44e-1)" "unprognostic (3.34e-1)" "unprognostic (8.42e-3)" "unprognostic (2.62e-1)" WWTR1 "DKFZp586I1419, TAZ" ENSG00000018408 "WW domain containing transcription regulator 1" Q9GZV5 3 149517235-149736714 "Cancer-related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" Activator "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 564.7;Lymphatic endothelial cells: 576.6;Transitional alveolar cells: 546.4;Vascular endothelial cells: 781.1" "Cell type enhanced" "Detected in many" "Endothelial cells: 781.1" "Cell type enhanced" "Detected in all" "endothelial cell: 964.7;ependymal cell: 501.0;fibroblast: 464.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Kidney - Endothelial cells, Lung - Endothelial cells, Pituitary gland - Endothelial cells, Skeletal muscle - Endothelial cells, Skin - Endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 608129.3;Glomeruli: 1496921.2" "Tissue enriched" "Detected in single" 148 "ovary: 14826.8" "HPA007415, CAB017483, CAB068248" Enhanced Supported "Nucleoplasm,Nuclear bodies,Cytosol" NA NA "Cluster 9: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - ECM organization" "Cluster 39: Astrocytes - Mixed function" "Cluster 69: Skin cancer - ECM organization" "Cluster 12: Endothelial cells - Angiogenesis & vascular homeostasis" 55 "Nucleoplasm, Nuclear bodies" Cytosol "CAB017483: , CAB068248: , HPA007415: " "unprognostic (7.21e-2)" "unprognostic (9.36e-2)" "unprognostic (1.45e-1)" "unprognostic (2.80e-2)" "unprognostic (3.61e-2)" "unprognostic (2.55e-2)" "unprognostic (2.99e-2)" "potential prognostic unfavorable (9.35e-7)" "unprognostic (2.04e-1)" "unprognostic (3.02e-3)" "potential prognostic favorable (2.87e-7)" "unprognostic (3.03e-3)" "unprognostic (7.62e-2)" "unprognostic (2.54e-2)" "unprognostic (3.34e-2)" "unprognostic (9.88e-2)" "unprognostic (2.39e-3)" "unprognostic (1.35e-1)" "unprognostic (2.41e-1)" "unprognostic (2.15e-2)" "unprognostic (2.54e-2)" "unprognostic (3.27e-2)" "unprognostic (6.95e-2)" "unprognostic (2.73e-1)" "unprognostic (1.66e-1)" "unprognostic (1.95e-2)" "unprognostic (8.63e-3)" "unprognostic (3.59e-2)" "unprognostic (1.95e-1)" "unprognostic (2.69e-2)" "unprognostic (5.71e-2)" XAF1 "BIRC4BP, HSXIAPAF1, XIAPAF1" ENSG00000132530 "XIAP associated factor 1" Q6GPH4 17 6755447-6775647 "Predicted intracellular proteins" Apoptosis "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 75.5;Leydig cells: 87.4;Microglia: 125.0;Ovarian stromal cells: 128.2;Vascular endothelial cells: 153.5" "Cell type enhanced" "Detected in many" "Endothelial cells: 153.5;Stromal cells: 128.2" "Cell type enhanced" "Detected in many" "central nervous system macrophage: 177.3;endothelial cell: 566.3;pericyte: 207.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 4908 "lymphoid tissue: 490811.8" HPA057302 Approved Supported Nucleoplasm,Mitochondria Yes NA "Cluster 28: Neutrophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 104: Brain endothelial cells - Blood brain barrier" 30 "Nucleoplasm, Mitochondria" "HPA057302: " "unprognostic (2.25e-2)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-2)" "unprognostic (7.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.02e-2)" "unprognostic (2.31e-2)" "unprognostic (3.97e-1)" "potential prognostic unfavorable (6.02e-4)" "unprognostic (1.90e-1)" "unprognostic (3.09e-1)" "unprognostic (1.92e-2)" "potential prognostic favorable (3.20e-4)" "unprognostic (6.57e-2)" "unprognostic (3.33e-2)" "unprognostic (6.17e-2)" "unprognostic (1.19e-1)" "unprognostic (6.79e-2)" "unprognostic (1.29e-1)" "unprognostic (5.20e-3)" "potential prognostic unfavorable (1.39e-4)" "unprognostic (1.51e-1)" "unprognostic (1.48e-1)" "unprognostic (4.54e-3)" "unprognostic (2.12e-1)" "unprognostic (4.29e-1)" "unprognostic (1.62e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" XAGE5 "CT12.5, GAGED5, XAGE-5" ENSG00000171405 "X antigen family member 5" Q8WWM1 X 52811287-52818301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 12 "testis: 1.1" "Group enriched" "Detected in some" 6 "Differentiating spermatogonia: 15.5;Early primary spermatocytes: 9.8;Undifferentiated spermatogonia: 9.2" "Cell type enriched" "Detected in some" 8 "Spermatogenic cell types: 15.5" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 5 "Liver Hepatocellular Carcinoma (TCGA): 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "Bone cancer: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052507, HPA055941" Uncertain Approved Nucleoplasm,Vesicles No No "Cluster 57: Testis - Spermatogenesis" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 106: Spermatogonia - Spermatogonial differentiation" "Nucleoplasm, Vesicles" "HPA052507: , HPA055941: " "potential prognostic unfavorable (5.18e-4)" "unprognostic (1.20e-1)" XDH "XO, XOR" ENSG00000158125 "Xanthine dehydrogenase" P47989 2 31334321-31414742 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "breast: 39.2;intestine: 46.6;liver: 64.0" "Cell type enriched" "Detected in many" 16 "Breast lactating cells: 7985.9" "Cell type enriched" "Detected in many" 16 "Secretory cells: 7985.9" "Cell type enhanced" "Detected in some" "cerebellar inhibitory: 10.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "head and neck cancer: 13.0" "Colon - Colon enterocytes, Liver - Hepatocytes, Pituitary gland - Corticotropes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in some" 1 "Hepatocytes: 99453578.0" "Group enriched" "Detected in many" "intestine: 64425339.0;liver: 90669545.7" "HPA062641, HPA069323" Supported Uncertain Nucleoplasm,Nucleoli "Intracellular and membrane" Enzyme No No 800000 "Cluster 26: Kidney & Intestine - Metabolism" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 4: Breast lactating luminal cells - Lactation" 3 Nucleoplasm Nucleoli "HPA062641: , HPA069323: " "unprognostic (3.87e-1)" "unprognostic (4.92e-2)" "unprognostic (1.60e-1)" "unprognostic (3.12e-2)" "unprognostic (6.42e-3)" "unprognostic (3.77e-3)" "unprognostic (2.49e-2)" "unprognostic (9.47e-2)" "unprognostic (2.78e-3)" "potential prognostic favorable (8.04e-4)" "unprognostic (4.76e-2)" "unprognostic (2.08e-2)" "unprognostic (2.86e-2)" "unprognostic (1.79e-3)" "unprognostic (4.89e-2)" "unprognostic (1.39e-1)" "unprognostic (3.76e-3)" "unprognostic (2.56e-1)" "unprognostic (1.95e-2)" "unprognostic (2.37e-3)" "unprognostic (7.79e-3)" "unprognostic (9.32e-2)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" XK "Kx, NA, NAC, X1k, XKR1" ENSG00000047597 "X-linked Kx blood group antigen, Kell and VPS13A binding protein" P51811 X 37685791-37732130 "Blood group antigen proteins, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Blood group antigen" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 13.4;intestine: 11.4;stomach 1: 10.9" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 64.7;Foveolar cells: 47.7;Megakaryocyte progenitors: 36.8;Megakaryocytes: 43.3;Platelets: 247.0" "Cell type enhanced" "Detected in many" "Erythrocytes: 64.7;Platelets: 247.0" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in many" "Rectum Adenocarcinoma (TCGA): 8.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 53 "basophil: 10.2;eosinophil: 5.8" "Lineage enriched" "Detected in single" 103 "granulocytes: 10.2" "Cancer enhanced" "Detected in many" "Myeloma: 12.3" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Prostate - Smooth muscle cells, Spleen - Erythrocytes, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2731 "Astrocytes and Neuropil: 420282.8;Microglia and Neuropil: 125947.2" "Not detected" "Not detected" HPA019036 Approved Approved Nucleoplasm,Vesicles,Mitochondria No No "Cluster 22: Eosinophils - Transcription" "Cluster 34: Lymphoid tissue - Adaptive immune response" "Cluster 1: Neurons - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 47: Platelets - Hemostasis" Mitochondria "Nucleoplasm, Vesicles" "HPA019036: " "unprognostic (7.94e-3)" "unprognostic (1.06e-1)" "unprognostic (3.11e-1)" "unprognostic (1.97e-3)" "unprognostic (2.13e-1)" "unprognostic (1.19e-3)" "unprognostic (3.59e-1)" "unprognostic (2.15e-3)" "potential prognostic unfavorable (2.05e-4)" "unprognostic (1.72e-1)" "unprognostic (9.08e-3)" "unprognostic (5.40e-3)" "unprognostic (4.66e-2)" "unprognostic (5.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.25e-2)" "unprognostic (5.43e-3)" "unprognostic (1.23e-1)" "unprognostic (2.21e-1)" "unprognostic (2.11e-1)" "unprognostic (9.85e-2)" "unprognostic (6.72e-2)" XNDC1N ENSG00000254469 "XRCC1 N-terminal domain containing 1, N-terminal like" Q6ZNB5 11 71865504-71928654 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 29.3;Bergmann glia: 35.8;Choroid plexus epithelial cells: 39.5;Distal convoluted tubule cells: 70.0;Ependymal cells: 34.5;Loop of henle epithelial cells: 80.7;Microglia: 27.2;Oligodendrocyte progenitor cells: 27.7;Oligodendrocytes: 49.3;Papillary tip epithelial cells: 52.0;Podocytes: 40.3;Proximal tubule cells: 72.5;Renal collecting duct intercalated cells: 79.0;Renal collecting duct principal cells: 74.7;Renal connecting tubule cells: 84.3" "Group enriched" "Detected in some" 8 "Ciliated cells: 39.5;Ductal cells: 84.3;Glial cells: 49.3;Neuronal cells: 22.1;Renal nephron cells: 80.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051121, HPA051124" Uncertain Enhanced "Nucleoli,Mitotic chromosome" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" Nucleoli "Mitotic chromosome" "HPA051121: , HPA051124: " "unprognostic (7.17e-2)" "unprognostic (8.39e-2)" "unprognostic (6.71e-2)" "unprognostic (4.59e-2)" "unprognostic (1.89e-1)" "unprognostic (2.74e-2)" "unprognostic (8.37e-3)" "unprognostic (2.13e-1)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (1.03e-2)" "unprognostic (7.32e-2)" "unprognostic (2.16e-2)" "unprognostic (1.43e-2)" "unprognostic (2.05e-1)" "unprognostic (2.66e-3)" "unprognostic (2.57e-2)" "unprognostic (6.11e-2)" "unprognostic (7.20e-2)" "unprognostic (1.69e-2)" "unprognostic (2.52e-2)" "unprognostic (1.45e-2)" "unprognostic (3.43e-1)" "unprognostic (5.78e-2)" "unprognostic (4.33e-3)" "potential prognostic unfavorable (1.01e-4)" "unprognostic (8.61e-2)" "unprognostic (1.29e-1)" "unprognostic (1.10e-1)" "unprognostic (2.19e-1)" XPC "RAD4, XPCC" ENSG00000154767 "XPC complex subunit, DNA damage recognition and repair factor" Q01831 3 14145147-14178621 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" "CAB009932, HPA035707, HPA069673" Supported Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 60 Nucleoplasm "Plasma membrane" "CAB009932: , HPA035707: , HPA069673: " "unprognostic (1.66e-2)" "unprognostic (5.63e-2)" "unprognostic (5.04e-2)" "unprognostic (5.07e-1)" "unprognostic (1.28e-1)" "unprognostic (9.67e-2)" "unprognostic (3.68e-1)" "unprognostic (1.66e-1)" "unprognostic (2.23e-2)" "unprognostic (1.44e-2)" "validated prognostic favorable (1.12e-7)" "validated prognostic favorable (1.69e-4)" "unprognostic (4.26e-3)" "unprognostic (1.31e-1)" "unprognostic (6.60e-2)" "unprognostic (3.11e-2)" "unprognostic (4.15e-2)" "unprognostic (2.18e-1)" "unprognostic (2.89e-1)" "unprognostic (8.15e-3)" "unprognostic (6.29e-2)" "unprognostic (5.76e-2)" "unprognostic (1.23e-1)" "unprognostic (3.88e-1)" "unprognostic (3.36e-2)" "unprognostic (4.83e-3)" "unprognostic (2.47e-1)" "unprognostic (1.29e-1)" "unprognostic (1.78e-1)" "unprognostic (3.70e-2)" "unprognostic (1.01e-2)" XPO1 "CRM-1, CRM1, emb" ENSG00000082898 "Exportin 1" O14980 2 61476032-61538741 "Cancer-related genes, Essential proteins, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, mRNA transport, Protein transport, Transport" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB010184, HPA042933" Supported Approved "Nucleoplasm,Nuclear membrane,Vesicles,Primary cilium,Primary cilium tip,Cytosol" NA NA 310000 "Cluster 13: Non-specific - Mitochondria" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 27: Non-specific - Cell proliferation" 200 "Nucleoplasm, Nuclear membrane" "Vesicles, Primary cilium, Primary cilium tip, Cytosol" "CAB010184: , HPA042933: " "unprognostic (1.40e-1)" "unprognostic (2.69e-2)" "unprognostic (1.58e-1)" "unprognostic (2.22e-2)" "unprognostic (1.41e-1)" "unprognostic (3.88e-2)" "unprognostic (9.88e-2)" "unprognostic (7.21e-3)" "unprognostic (2.27e-1)" "unprognostic (1.77e-2)" "potential prognostic favorable (1.38e-4)" "unprognostic (2.64e-2)" "unprognostic (1.35e-1)" "unprognostic (6.24e-3)" "unprognostic (5.86e-2)" "unprognostic (1.04e-2)" "unprognostic (3.57e-3)" "unprognostic (3.36e-1)" "unprognostic (6.90e-3)" "unprognostic (8.17e-3)" "unprognostic (4.32e-1)" "validated prognostic unfavorable (4.44e-5)" "validated prognostic unfavorable (9.55e-4)" "unprognostic (9.94e-2)" "unprognostic (1.09e-3)" "unprognostic (6.72e-2)" "unprognostic (1.41e-2)" "unprognostic (1.84e-1)" "unprognostic (2.06e-1)" "unprognostic (2.09e-2)" "unprognostic (7.97e-3)" XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 10 "Neutrophils: 2960.1" "Cell type enriched" "Detected in all" 19 "Neutrophils: 2960.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 203.4" "Lineage enriched" "Detected in all" 9 "granulocytes: 203.4" "Low cancer specificity" "Detected in all" "Lung - Neutrophils_2, Spleen - Neutrophils_2, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1759616.4;Granulosa cells: 1915872.2" "Tissue enriched" "Detected in some" "intestine: 2202526.0" HPA038246 Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 5: Spleen - Immune response" "Cluster 27: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 11 "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: " "unprognostic (2.25e-2)" "unprognostic (1.30e-1)" "unprognostic (1.94e-2)" "unprognostic (1.98e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (4.03e-1)" "potential prognostic favorable (2.95e-5)" "unprognostic (5.07e-2)" "unprognostic (1.67e-1)" "validated prognostic unfavorable (5.67e-9)" "validated prognostic unfavorable (1.42e-4)" "unprognostic (2.22e-1)" "potential prognostic unfavorable (9.00e-5)" "unprognostic (2.38e-2)" "unprognostic (1.28e-2)" "unprognostic (4.57e-3)" "unprognostic (5.65e-2)" "unprognostic (2.51e-1)" "unprognostic (6.39e-2)" "unprognostic (2.54e-3)" "unprognostic (6.46e-2)" "potential prognostic unfavorable (1.23e-5)" "unprognostic (1.50e-1)" "unprognostic (2.29e-1)" "unprognostic (4.76e-2)" "unprognostic (5.91e-2)" "unprognostic (1.48e-1)" "unprognostic (1.62e-1)" "unprognostic (3.00e-1)" "unprognostic (1.30e-1)" XRCC1 RCC ENSG00000073050 "X-ray repair cross complementing 1" P18887 19 43543311-43580473 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Pituitary gland - Lactotropes, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in all" "intestine: 4669008.1" "CAB005427, HPA006717" Supported Enhanced Nucleoplasm NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 54: Non-specific - Ribosome" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 63 Nucleoplasm "CAB005427: , HPA006717: " "unprognostic (2.44e-2)" "unprognostic (1.71e-2)" "unprognostic (1.06e-1)" "unprognostic (2.64e-1)" "unprognostic (1.92e-1)" "unprognostic (2.65e-1)" "unprognostic (3.24e-1)" "unprognostic (3.75e-1)" "unprognostic (5.58e-2)" "unprognostic (2.66e-1)" "unprognostic (9.76e-3)" "unprognostic (7.12e-2)" "unprognostic (1.40e-3)" "potential prognostic unfavorable (4.58e-5)" "unprognostic (1.61e-2)" "unprognostic (6.29e-2)" "unprognostic (4.40e-3)" "potential prognostic favorable (9.87e-5)" "unprognostic (7.45e-3)" "unprognostic (1.52e-1)" "unprognostic (4.63e-1)" "unprognostic (7.67e-2)" "unprognostic (2.23e-1)" "unprognostic (5.49e-2)" "unprognostic (6.80e-2)" "unprognostic (1.61e-1)" "unprognostic (1.36e-1)" "unprognostic (1.13e-1)" "unprognostic (2.69e-3)" "unprognostic (1.23e-1)" "unprognostic (2.03e-1)" XRCC3 ENSG00000126215 "X-ray repair cross complementing 3" O43542 14 103697609-103715504 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 122.9;Epicardial cells: 166.0;Erythrocyte progenitors: 38.1;Megakaryocyte progenitors: 39.0" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 166.0;Myocytes: 122.9" "Cell type enhanced" "Detected in many" "Bergmann glia: 15.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 302 "Granulosa cells: 27420.8;Oocytes: 33062.2" "Not detected" "Not detected" "HPA062422, HPA068953" Enhanced Nucleoplasm NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 58: Skin - Keratinization" "Cluster 6: Non-specific - Immune response" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 17 Nucleoplasm "HPA062422: , HPA068953: " "unprognostic (3.19e-2)" "unprognostic (6.99e-3)" "unprognostic (1.28e-1)" "unprognostic (4.42e-2)" "unprognostic (1.42e-1)" "unprognostic (4.09e-1)" "unprognostic (1.80e-1)" "unprognostic (1.26e-1)" "unprognostic (8.83e-2)" "unprognostic (1.26e-2)" "potential prognostic unfavorable (3.79e-4)" "unprognostic (5.33e-2)" "unprognostic (7.28e-2)" "potential prognostic unfavorable (6.54e-5)" "unprognostic (1.14e-2)" "unprognostic (5.41e-2)" "unprognostic (3.85e-3)" "unprognostic (1.37e-1)" "unprognostic (2.81e-2)" "unprognostic (3.47e-2)" "unprognostic (2.27e-1)" "unprognostic (1.86e-3)" "unprognostic (2.65e-2)" "unprognostic (6.31e-3)" "unprognostic (3.15e-2)" "unprognostic (2.35e-1)" "unprognostic (1.11e-3)" "unprognostic (1.71e-1)" "unprognostic (2.76e-1)" "unprognostic (2.36e-1)" "unprognostic (8.00e-3)" XRCC6 "D22S671, D22S731, G22P1, KU70, ML8" ENSG00000196419 "X-ray repair cross complementing 6" P12956 22 41621163-41664048 "Cancer-related genes, Essential proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair, Host-virus interaction, Immunity, Innate immunity, Transcription, Transcription regulation" "Activator, DNA-binding, Helicase, Hydrolase, Lyase, Multifunctional enzyme" "Cancer-related genes, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 478.1;Early primary spermatocytes: 532.5;Late primary spermatocytes: 494.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB004254, HPA047549, HPA062226" Enhanced Enhanced Nucleoplasm No No 1600000 "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 39: Testis - Nuclear processes" "Cluster 21: Non-specific - Metabolism" "Cluster 66: Non-specific - Mitochondria" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 292 Nucleoplasm "CAB004254: , HPA047549: , HPA062226: " "unprognostic (1.29e-2)" "unprognostic (2.38e-2)" "unprognostic (7.72e-2)" "potential prognostic favorable (6.58e-4)" "unprognostic (2.20e-2)" "unprognostic (3.56e-1)" "unprognostic (6.04e-3)" "unprognostic (3.17e-1)" "unprognostic (9.02e-3)" "potential prognostic unfavorable (1.87e-4)" "potential prognostic favorable (8.25e-6)" "unprognostic (4.17e-3)" "unprognostic (3.53e-1)" "potential prognostic unfavorable (1.60e-4)" "unprognostic (2.93e-3)" "unprognostic (1.14e-3)" "unprognostic (1.27e-1)" "unprognostic (5.49e-2)" "unprognostic (7.33e-3)" "unprognostic (1.19e-1)" "unprognostic (3.04e-2)" "unprognostic (6.21e-2)" "unprognostic (8.16e-2)" "unprognostic (2.17e-1)" "potential prognostic favorable (7.10e-4)" "unprognostic (6.03e-2)" "unprognostic (4.54e-2)" "unprognostic (3.38e-1)" "unprognostic (3.80e-1)" "unprognostic (1.37e-1)" "unprognostic (3.00e-1)" YARS1 "tyrRS, YARS, YRS, YTS" ENSG00000134684 "Tyrosyl-tRNA synthetase 1" P54577 1 32775237-32818031 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, RNA-binding, tRNA-binding" "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreas epithelial cells: 199641154.5;Pancreatic islets: 155421610.8" "Tissue enhanced" "Detected in all" "pancreas: 228167153.9" "HPA017936, HPA018950, HPA018954" Enhanced Supported "Nuclear bodies,Cytosol" No No 930000 "Cluster 5: Non-specific - Cell proliferation" "Cluster 36: Brain & Liver - Signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 13: Non-specific - Mixed function" "Cluster 17: Non-specific - RNA processing" 19 Cytosol "Nuclear bodies" "HPA017936: , HPA018950: , HPA018954: " "unprognostic (1.77e-2)" "unprognostic (8.99e-3)" "unprognostic (9.22e-2)" "unprognostic (1.05e-1)" "unprognostic (5.68e-3)" "unprognostic (4.71e-2)" "unprognostic (2.21e-1)" "unprognostic (1.35e-2)" "unprognostic (4.07e-3)" "unprognostic (2.90e-3)" "unprognostic (2.30e-2)" "unprognostic (7.23e-3)" "potential prognostic unfavorable (1.22e-9)" "unprognostic (5.31e-2)" "potential prognostic unfavorable (6.13e-4)" "unprognostic (8.80e-2)" "unprognostic (1.29e-1)" "unprognostic (1.18e-1)" "unprognostic (7.78e-3)" "unprognostic (1.18e-1)" "potential prognostic unfavorable (1.53e-4)" "unprognostic (2.57e-3)" "unprognostic (1.88e-1)" "unprognostic (2.52e-2)" "unprognostic (3.54e-1)" "unprognostic (5.10e-3)" "unprognostic (1.66e-1)" "unprognostic (2.25e-1)" "unprognostic (1.26e-1)" YARS2 "CGI-04, FLJ13995, mt-TyrRS" ENSG00000139131 "Tyrosyl-tRNA synthetase 2" Q9Y2Z4 12 32727490-32755897 "Disease related genes, Enzymes, Essential proteins, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 115.7;Epicardial cells: 122.8" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Group enriched" "Detected in many" "intestine: 7512207.8;lymphoid tissue: 3255601.3" "HPA038721, HPA057610, HPA074097" Uncertain Supported "Nuclear bodies,Mitochondria" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 38: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 108 Mitochondria "Nuclear bodies" "HPA038721: , HPA057610: , HPA074097: " "unprognostic (6.05e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-1)" "unprognostic (1.15e-3)" "unprognostic (4.96e-2)" "unprognostic (1.05e-2)" "unprognostic (1.91e-1)" "unprognostic (1.35e-3)" "unprognostic (2.20e-2)" "unprognostic (3.14e-2)" "unprognostic (2.57e-2)" "unprognostic (1.11e-2)" "unprognostic (7.33e-3)" "validated prognostic unfavorable (2.31e-7)" "validated prognostic unfavorable (3.87e-4)" "unprognostic (1.61e-3)" "unprognostic (3.60e-3)" "unprognostic (1.68e-1)" "unprognostic (1.56e-1)" "unprognostic (2.55e-1)" "unprognostic (2.05e-2)" "unprognostic (2.05e-3)" "unprognostic (1.20e-3)" "unprognostic (1.38e-2)" "unprognostic (1.44e-2)" "unprognostic (1.84e-1)" "unprognostic (5.36e-2)" "unprognostic (2.58e-1)" "unprognostic (1.63e-1)" "unprognostic (9.40e-2)" "unprognostic (1.07e-1)" YDJC ENSG00000161179 "YdjC chitooligosaccharide deacetylase homolog" A8MPS7 22 21628089-21630064 "Predicted intracellular proteins" "Carbohydrate metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Esophageal basal cells: 83.0;Extravillous trophoblasts: 83.5;Migrating cytotrophoblasts: 70.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fallopian tube cells: 59262.7;Proximal tubules: 76392.3" "Group enriched" "Detected in some" "cerebral cortex: 335112.7;salivary gland: 274993.7" HPA001501 Approved "Golgi apparatus,Vesicles,Cytosol" NA NA "Cluster 25: Non-specific - Unknown function" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 97: Non-specific - Cellular respiration" "Golgi apparatus, Vesicles" Cytosol "HPA001501: " "unprognostic (1.50e-1)" "unprognostic (8.60e-2)" "unprognostic (7.64e-2)" "unprognostic (2.52e-1)" "unprognostic (9.77e-2)" "unprognostic (6.11e-3)" "unprognostic (4.12e-2)" "unprognostic (4.03e-3)" "unprognostic (1.16e-2)" "unprognostic (2.75e-1)" "unprognostic (3.42e-3)" "unprognostic (2.68e-2)" "unprognostic (6.09e-2)" "unprognostic (1.44e-3)" "unprognostic (3.97e-3)" "unprognostic (1.11e-2)" "unprognostic (6.81e-2)" "unprognostic (1.35e-1)" "unprognostic (4.44e-2)" "unprognostic (1.38e-3)" "unprognostic (1.74e-1)" "unprognostic (1.21e-2)" "unprognostic (2.54e-1)" "unprognostic (2.14e-1)" "unprognostic (3.70e-3)" "unprognostic (1.02e-1)" "unprognostic (1.03e-1)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (3.59e-2)" "unprognostic (1.12e-1)" YIPF2 "FinGER2, MGC3262" ENSG00000130733 "Yip1 domain family member 2" Q9BWQ6 19 10922185-10928681 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Epididymal principal cells: 157.0;Esophageal apical cells: 160.5;Extravillous trophoblasts: 168.5;Late primary spermatocytes: 279.5;Syncytiotrophoblasts: 250.1" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 279.5;Trophoblast cells: 250.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Pituitary gland - Lactotropes, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 252 "salivary gland: 25215.8" HPA019902 Approved Approved "Golgi apparatus,Mitochondria" No No "Cluster 29: Non-specific - Unknown function" "Cluster 8: Pancreas - Proteolysis" "Cluster 44: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 8: Non-specific - Secretory pathway" 26 "Golgi apparatus, Mitochondria" "HPA019902: " "unprognostic (1.21e-1)" "unprognostic (3.55e-2)" "unprognostic (6.87e-2)" "unprognostic (2.41e-2)" "unprognostic (1.55e-2)" "unprognostic (5.88e-2)" "unprognostic (4.26e-2)" "unprognostic (2.26e-1)" "unprognostic (3.20e-1)" "unprognostic (7.32e-2)" "unprognostic (5.57e-2)" "potential prognostic unfavorable (7.33e-4)" "unprognostic (2.08e-1)" "unprognostic (6.21e-2)" "unprognostic (4.29e-3)" "unprognostic (9.19e-2)" "unprognostic (2.27e-2)" "unprognostic (1.17e-1)" "unprognostic (1.35e-1)" "unprognostic (1.83e-2)" "unprognostic (9.00e-2)" "unprognostic (2.80e-1)" "unprognostic (1.34e-1)" "unprognostic (1.20e-1)" "unprognostic (2.37e-1)" "unprognostic (1.56e-2)" "unprognostic (8.11e-2)" "unprognostic (6.76e-2)" "unprognostic (8.94e-3)" "unprognostic (4.06e-2)" "unprognostic (7.40e-2)" YKT6 ENSG00000106636 "YKT6 v-SNARE homolog" O15498 7 44200959-44214294 "Essential proteins, Metabolic proteins, Predicted intracellular proteins, Transporters" "ER-Golgi transport, Protein transport, Transport" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 170.3;Extravillous trophoblasts: 85.7" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 170.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA030817, HPA030818" Approved Approved Mitochondria,Cytosol No No 11000 "Cluster 45: Eosinophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 41: Monoamines - Neurotransmitter signalling" "Cluster 67: Non-specific - Unknown function" "Cluster 8: Non-specific - Secretory pathway" 37 Cytosol Mitochondria "HPA030817: , HPA030818: " "unprognostic (2.19e-3)" "unprognostic (1.31e-2)" "unprognostic (5.14e-1)" "unprognostic (7.84e-2)" "unprognostic (1.20e-1)" "unprognostic (3.80e-1)" "unprognostic (3.20e-2)" "unprognostic (8.87e-2)" "potential prognostic unfavorable (2.92e-4)" "unprognostic (1.02e-1)" "unprognostic (3.18e-3)" "unprognostic (3.44e-2)" "unprognostic (2.11e-1)" "validated prognostic unfavorable (1.39e-6)" "validated prognostic unfavorable (8.35e-5)" "potential prognostic unfavorable (3.58e-4)" "unprognostic (4.79e-3)" "unprognostic (3.71e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (7.53e-4)" "unprognostic (3.48e-1)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (8.23e-4)" "unprognostic (2.99e-1)" "unprognostic (5.80e-2)" "unprognostic (2.36e-1)" "unprognostic (3.19e-1)" "unprognostic (1.22e-1)" "unprognostic (1.03e-1)" "unprognostic (4.21e-3)" "unprognostic (7.59e-3)" YWHAB YWHAA ENSG00000166913 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta" P31946 20 44885702-44908532 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 1215.3" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB003759, HPA007925, HPA011212, HPA061603, CAB080288, CAB080290" Enhanced Supported Cytosol NA NA 88000000 "Cluster 42: Non-specific - Vesicular transport" "Cluster 10: Brain - Synaptic signal transduction" "Cluster 14: Neurons - Synaptic function" "Cluster 62: Non-specific - Plasma proteins" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 858 Cytosol "CAB003759: , CAB080288: , CAB080290: , HPA007925: , HPA011212: , HPA061603: " "unprognostic (9.87e-3)" "unprognostic (1.16e-3)" "unprognostic (1.20e-1)" "unprognostic (4.32e-2)" "unprognostic (2.70e-1)" "unprognostic (2.93e-1)" "unprognostic (2.37e-1)" "unprognostic (1.70e-2)" "unprognostic (9.90e-3)" "unprognostic (3.41e-2)" "potential prognostic favorable (8.61e-7)" "unprognostic (2.16e-1)" "unprognostic (4.09e-2)" "potential prognostic unfavorable (7.32e-6)" "unprognostic (7.57e-3)" "unprognostic (1.92e-2)" "unprognostic (4.26e-3)" "unprognostic (1.29e-2)" "unprognostic (1.44e-1)" "unprognostic (1.11e-1)" "unprognostic (4.40e-3)" "unprognostic (1.36e-2)" "unprognostic (3.19e-2)" "unprognostic (2.30e-1)" "unprognostic (1.68e-1)" "unprognostic (5.59e-3)" "unprognostic (1.62e-1)" "unprognostic (2.45e-1)" "unprognostic (5.81e-1)" "unprognostic (9.01e-2)" "unprognostic (1.87e-1)" YWHAE FLJ45465 ENSG00000108953 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon" P62258 17 1344275-1400222 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 238.3;Megakaryocytes: 191.6;Renal collecting duct intercalated cells: 173.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 238.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Stomach - Mitotic cells (Stomach), Testis - Spermatocytes, Testis - Spermatogonia, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA008445, CAB016200, CAB021109, CAB047350, HPA061603" Approved Supported Cytosol NA NA 96000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 1077 Cytosol "CAB016200: , CAB021109: , CAB047350: , HPA008445: , HPA061603: " "unprognostic (2.52e-2)" "unprognostic (4.86e-2)" "potential prognostic unfavorable (3.76e-4)" "unprognostic (1.15e-1)" "unprognostic (1.45e-1)" "unprognostic (1.00e-1)" "unprognostic (2.68e-2)" "unprognostic (1.95e-2)" "unprognostic (3.07e-2)" "unprognostic (1.94e-3)" "potential prognostic favorable (1.27e-7)" "unprognostic (1.03e-2)" "unprognostic (2.01e-1)" "unprognostic (2.42e-3)" "unprognostic (3.96e-2)" "potential prognostic unfavorable (3.92e-4)" "unprognostic (6.70e-2)" "unprognostic (1.75e-1)" "unprognostic (2.55e-1)" "unprognostic (1.65e-1)" "unprognostic (2.07e-1)" "unprognostic (4.51e-2)" "unprognostic (2.26e-2)" "unprognostic (1.64e-1)" "unprognostic (8.75e-2)" "unprognostic (2.20e-2)" "unprognostic (3.77e-1)" "unprognostic (4.27e-2)" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.91e-2)" YWHAG "14-3-3GAMMA, PPP1R170" ENSG00000170027 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma" P61981 7 76326799-76358991 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 355.0;skeletal muscle: 327.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Adipocytes (Subcutaneous), Adipose visceral - Adipocytes (Visceral), Breast - Adipocytes (Breast)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" "Astrocytes and Neuropil: 263456881.0;Microglia and Neuropil: 339716115.1;Neurons: 349542302.4;Skeletal myofibers: 340165491.3" "Tissue enhanced" "Detected in all" "cerebral cortex: 674676712.4" "CAB013274, CAB018389, HPA026918, HPA061603" Approved Approved Supported Vesicles,Cytosol NA NA 68000000 "Cluster 10: Non-specific - Membrane trafficking" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 39: Non-specific - Transcription" "Cluster 26: Keratinocytes - Keratinization" 1193 Cytosol Vesicles "CAB013274: , CAB018389: , HPA026918: , HPA061603: " "unprognostic (1.94e-2)" "unprognostic (1.50e-2)" "unprognostic (1.35e-1)" "potential prognostic unfavorable (2.92e-5)" "unprognostic (6.92e-2)" "unprognostic (1.40e-2)" "unprognostic (1.95e-2)" "unprognostic (2.61e-3)" "potential prognostic unfavorable (8.83e-4)" "unprognostic (2.51e-3)" "unprognostic (1.04e-3)" "unprognostic (4.60e-3)" "unprognostic (5.75e-2)" "unprognostic (9.37e-3)" "potential prognostic unfavorable (3.06e-5)" "validated prognostic unfavorable (2.86e-5)" "validated prognostic unfavorable (1.54e-4)" "unprognostic (1.72e-1)" "unprognostic (2.25e-1)" "unprognostic (2.91e-1)" "unprognostic (1.30e-1)" "potential prognostic unfavorable (9.03e-4)" "unprognostic (5.97e-3)" "unprognostic (1.99e-2)" "unprognostic (2.68e-1)" "unprognostic (3.69e-1)" "unprognostic (9.77e-2)" "unprognostic (1.39e-1)" "unprognostic (1.70e-1)" "unprognostic (8.98e-2)" "unprognostic (2.06e-1)" YWHAH YWHA1 ENSG00000128245 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta" Q04917 22 31944522-31957603 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "blood vessel: 288.0;brain: 728.3" "Group enriched" "Detected in many" 5 "Megakaryocytes: 1013.8;Platelets: 2830.9" "Group enriched" "Detected in many" 5 "Megakaryocytes: 1013.8;Platelets: 2830.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes and Neuropil: 187798736.6;Neurons: 200249066.3" "Tissue enhanced" "Detected in all" "cerebral cortex: 452845637.8" "CAB025918, HPA061603" Uncertain Approved "Nucleoplasm,Nucleoli rim,Cytosol" NA NA 54000000 "Cluster 25: Non-specific - Unknown function" "Cluster 73: Brain - Neuronal signaling" "Cluster 14: Neurons - Synaptic function" "Cluster 66: Non-specific - Mitochondria" "Cluster 47: Platelets - Hemostasis" 711 Cytosol "Nucleoplasm, Nucleoli rim" "CAB025918: , HPA061603: " "unprognostic (3.21e-2)" "unprognostic (1.07e-1)" "unprognostic (9.66e-2)" "unprognostic (8.48e-2)" "unprognostic (1.32e-1)" "unprognostic (8.81e-2)" "unprognostic (3.50e-2)" "unprognostic (1.11e-1)" "unprognostic (6.51e-2)" "unprognostic (3.15e-1)" "potential prognostic favorable (2.37e-4)" "unprognostic (5.65e-3)" "unprognostic (4.61e-2)" "potential prognostic unfavorable (9.59e-5)" "unprognostic (2.62e-3)" "unprognostic (1.85e-2)" "unprognostic (2.91e-2)" "unprognostic (1.65e-1)" "unprognostic (4.33e-1)" "unprognostic (8.31e-2)" "unprognostic (3.49e-1)" "unprognostic (1.35e-1)" "unprognostic (9.92e-2)" "unprognostic (5.93e-2)" "unprognostic (1.60e-2)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (1.95e-1)" "unprognostic (3.07e-1)" "unprognostic (2.88e-1)" YWHAQ "14-3-3, HS1" ENSG00000134308 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta" P27348 2 9583967-9630997 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skeletal muscle - Endothelial cells, Skin - Outer root sheath cells, Testis - Spermatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "HPA007925, CAB010286, HPA061603" Approved Supported "Nucleoplasm,Nucleoli rim,Cytosol" NA NA 71000000 "Cluster 1: T-cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 26: Non-specific - Mitochondria & RNA binding" "Cluster 20: Non-specific - Transcription regulation" 554 Cytosol "Nucleoplasm, Nucleoli rim" "CAB010286: , HPA007925: , HPA061603: " "unprognostic (6.65e-3)" "unprognostic (1.04e-2)" "unprognostic (2.01e-2)" "unprognostic (5.54e-2)" "unprognostic (4.44e-2)" "unprognostic (1.79e-1)" "unprognostic (7.87e-2)" "unprognostic (5.77e-2)" "unprognostic (6.05e-3)" "potential prognostic unfavorable (8.30e-5)" "potential prognostic favorable (8.28e-6)" "unprognostic (8.64e-2)" "unprognostic (1.04e-1)" "validated prognostic unfavorable (2.14e-5)" "validated prognostic unfavorable (6.34e-7)" "unprognostic (2.60e-3)" "unprognostic (5.24e-2)" "unprognostic (1.21e-1)" "unprognostic (7.47e-2)" "unprognostic (2.21e-1)" "unprognostic (1.70e-1)" "unprognostic (9.97e-2)" "potential prognostic unfavorable (2.27e-4)" "unprognostic (8.39e-2)" "unprognostic (8.71e-2)" "unprognostic (1.39e-1)" "unprognostic (1.16e-1)" "unprognostic (2.52e-2)" "unprognostic (1.86e-1)" "unprognostic (1.67e-1)" "unprognostic (3.20e-3)" YWHAZ "14-3-3-zeta, KCIP-1, YWHAD" ENSG00000164924 "Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta" P63104 8 100916523-100953388 "Essential proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Esophageal apical cells: 2310.1;Late spermatids: 3159.1;Neutrophils: 1644.3;Platelets: 1779.7" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 3159.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other)" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low tissue specificity" "Detected in all" "CAB005065, HPA061603" Approved Supported "Nucleoplasm,Nucleoli rim,Cytosol" NA NA 330000000 "Cluster 40: Monocytes - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 14: Neurons - Synaptic function" "Cluster 40: Non-specific - Unknown function" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 1066 Cytosol "Nucleoplasm, Nucleoli rim" "CAB005065: , HPA061603: " "unprognostic (8.17e-2)" "unprognostic (1.11e-3)" "unprognostic (1.74e-1)" "unprognostic (1.49e-1)" "unprognostic (3.48e-2)" "unprognostic (3.22e-2)" "unprognostic (3.15e-2)" "unprognostic (1.07e-1)" "unprognostic (4.54e-2)" "unprognostic (7.66e-2)" "potential prognostic favorable (3.10e-4)" "unprognostic (2.67e-1)" "potential prognostic unfavorable (8.80e-4)" "validated prognostic unfavorable (1.49e-4)" "validated prognostic unfavorable (6.36e-4)" "potential prognostic unfavorable (1.33e-4)" "unprognostic (2.44e-3)" "unprognostic (5.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.83e-2)" "potential prognostic unfavorable (1.93e-4)" "validated prognostic unfavorable (3.44e-4)" "validated prognostic unfavorable (1.48e-4)" "unprognostic (2.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.04e-1)" "unprognostic (2.40e-1)" "unprognostic (3.47e-1)" "unprognostic (3.70e-1)" "unprognostic (1.68e-1)" "unprognostic (3.30e-2)" YY1 "DELTA, INO80S, NF-E1, UCRBP, YIN-YANG-1" ENSG00000100811 "YY1 transcription factor" P25490 14 100238298-100282788 "Disease related genes, Essential proteins, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Differentiation, DNA damage, DNA recombination, DNA repair, Spermatogenesis, Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 4992644.0" "Tissue enriched" "Detected in many" "intestine: 7072998.0" "HPA000597, HPA001119, CAB009392" Supported Supported "Nucleoplasm,Nucleoli fibrillar center,Nuclear bodies" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 34: Non-specific - Mixed function" "Cluster 30: Non-specific - Gene expression regulation" "Cluster 17: Non-specific - RNA processing" 176 Nucleoplasm "Nucleoli fibrillar center, Nuclear bodies" "CAB009392: , HPA000597: , HPA001119: " "unprognostic (6.75e-2)" "unprognostic (1.15e-1)" "unprognostic (4.86e-3)" "unprognostic (2.61e-1)" "unprognostic (1.30e-1)" "unprognostic (8.13e-2)" "unprognostic (1.94e-2)" "unprognostic (1.76e-1)" "unprognostic (3.38e-2)" "unprognostic (6.59e-2)" "unprognostic (1.55e-3)" "unprognostic (1.68e-2)" "unprognostic (1.65e-2)" "potential prognostic unfavorable (1.15e-4)" "unprognostic (2.32e-2)" "potential prognostic unfavorable (4.76e-4)" "unprognostic (1.31e-1)" "unprognostic (6.67e-2)" "unprognostic (8.73e-2)" "unprognostic (9.65e-2)" "potential prognostic unfavorable (1.79e-4)" "potential prognostic unfavorable (5.50e-4)" "unprognostic (1.02e-3)" "unprognostic (3.91e-2)" "unprognostic (3.08e-1)" "unprognostic (3.24e-2)" "unprognostic (4.82e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-1)" "unprognostic (2.07e-1)" "unprognostic (2.46e-1)" YY2 ZNF631 ENSG00000230797 "YY2 transcription factor" O15391 X 21855987-21858740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 5.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 8930 "Pancreas epithelial cells: 893036.3" "Tissue enriched" "Detected in single" 105 "intestine: 10455.9" "HPA000597, HPA001119, HPA030335" Enhanced Approved "Nucleoplasm,Nuclear bodies" NA NA "Cluster 57: Testis - Spermatogenesis" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" 4 "Nucleoplasm, Nuclear bodies" "HPA000597: , HPA001119: , HPA030335: " "unprognostic (1.79e-1)" "unprognostic (4.78e-2)" "unprognostic (4.48e-1)" "unprognostic (6.99e-2)" "unprognostic (9.54e-2)" "unprognostic (6.06e-3)" "unprognostic (1.08e-1)" "unprognostic (1.51e-1)" "unprognostic (5.96e-2)" "unprognostic (2.15e-1)" "unprognostic (2.70e-1)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (5.91e-3)" "potential prognostic unfavorable (7.34e-4)" "unprognostic (1.76e-1)" "unprognostic (1.75e-2)" "unprognostic (2.78e-1)" "unprognostic (1.40e-1)" "unprognostic (8.36e-3)" "unprognostic (6.09e-2)" "unprognostic (1.77e-1)" "unprognostic (1.26e-3)" "unprognostic (6.76e-2)" "unprognostic (3.00e-1)" "unprognostic (4.48e-2)" "unprognostic (3.09e-2)" "unprognostic (4.68e-2)" ZAR1L Z3CXXC7 ENSG00000189167 "Zygote arrest 1 like" A6NP61 13 32303699-32315363 "Predicted intracellular proteins" "Differentiation, Oogenesis" "Developmental protein, RNA-binding" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enriched" "Detected in some" 14 "Oocytes: 55.3" "Cell type enriched" "Detected in some" 14 "Oocytes: 55.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 5433 "Oocytes: 543341.2" "Not detected" "Not detected" "HPA039540, HPA041319" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 46: Lymphoma - Humoral immune response" "Cluster 41: Oocytes - Oogenesis" Nucleoplasm "Nuclear speckles" "HPA039540: , HPA041319: " ZBED2 MGC10796 ENSG00000177494 "Zinc finger BED-type containing 2" Q9BTP6 3 111592900-111595346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 44.4;thyroid gland: 66.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 61.0;Basal keratinocytes: 11.8;Esophageal apical cells: 156.4;Esophageal basal cells: 12.4;Fallopian tube ciliated cells: 47.5;Medullary thymic epithelial cells: 40.8;Ocular epithelial cells: 11.3;Suprabasal keratinocytes: 24.0" "Cell type enhanced" "Detected in some" "Alveolar cells: 61.0;Apical squamous epithelial cells: 156.4;Ciliated cells: 47.5;Secretory gland support: 40.8" "Not detected" "Not detected" "Cancer enriched" "Detected in many" 6 "Thyroid Carcinoma (TCGA): 101.1" "Region enriched" "Detected in single" 5 "basal ganglia: 1.0" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Pituitary gland - Thyrotropes" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA029786 Approved "Nuclear bodies,Mitochondria,Cytosol" No No "Cluster 14: Non-specific - Unknown function" "Cluster 80: Thymus - Adaptive immune response" "Cluster 33: Neurons - Mixed function" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 1 "Mitochondria, Cytosol" "Nuclear bodies" "HPA029786: " "unprognostic (4.07e-2)" "unprognostic (1.02e-1)" "unprognostic (3.11e-1)" "unprognostic (3.93e-2)" "unprognostic (4.93e-3)" "unprognostic (2.87e-1)" "unprognostic (1.48e-3)" "unprognostic (1.53e-1)" "unprognostic (2.04e-1)" "unprognostic (4.24e-2)" "unprognostic (2.85e-2)" "unprognostic (1.07e-1)" "unprognostic (1.98e-1)" "validated prognostic unfavorable (6.03e-4)" "validated prognostic unfavorable (4.39e-4)" "unprognostic (2.54e-3)" "unprognostic (4.11e-1)" "unprognostic (1.92e-2)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (3.91e-1)" ZBTB11 "ZNF-U69274, ZNF913" ENSG00000066422 "Zinc finger and BTB domain containing 11" O95625 3 101648889-101677135 "Disease related genes, Essential proteins, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Neutrophil progenitors: 163.7" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 254079.6;Neurons: 367054.1" "Tissue enriched" "Detected in single" 246 "intestine: 24609.6" "HPA015328, HPA024138" Approved Enhanced Nucleoplasm NA NA "Cluster 33: Non-specific - ATP binding" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 31: Non-specific - Transcription" "Cluster 63: Non-specific - Protein processing" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 30 Nucleoplasm "HPA015328: , HPA024138: " "unprognostic (6.50e-2)" "unprognostic (1.50e-3)" "unprognostic (3.14e-2)" "unprognostic (1.44e-3)" "unprognostic (4.78e-2)" "unprognostic (2.11e-2)" "unprognostic (1.36e-1)" "unprognostic (8.71e-2)" "unprognostic (3.12e-2)" "unprognostic (7.93e-3)" "potential prognostic favorable (7.56e-6)" "unprognostic (4.82e-2)" "unprognostic (1.38e-1)" "unprognostic (3.60e-3)" "unprognostic (6.22e-2)" "unprognostic (2.89e-1)" "unprognostic (5.08e-2)" "unprognostic (1.40e-1)" "unprognostic (1.70e-1)" "unprognostic (2.48e-2)" "unprognostic (1.78e-3)" "unprognostic (2.30e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (2.81e-3)" "unprognostic (1.51e-3)" "unprognostic (1.50e-1)" "unprognostic (2.05e-2)" "unprognostic (3.53e-1)" "unprognostic (1.54e-1)" "unprognostic (7.78e-3)" "unprognostic (3.30e-1)" ZBTB14 "ZFP161, ZNF478" ENSG00000198081 "Zinc finger and BTB domain containing 14" O43829 18 5289019-5297053 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1369 "Granulosa cells: 154768.2;T-cells: 118974.7" "Tissue enriched" "Detected in some" "salivary gland: 78162.7" "HPA050758, HPA070819" Uncertain Supported Nucleoplasm,Nucleoli,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 18: Lymphoid tissue - Immune response" "Cluster 7: Non-specific - Ribosome" "Cluster 46: Lymphoma - Humoral immune response" "Cluster 9: T-cells - Adaptive immunity: Regulation" 62 Nucleoplasm "Nucleoli, Cytosol" "HPA050758: , HPA070819: " "unprognostic (1.22e-1)" "unprognostic (1.96e-1)" "unprognostic (1.22e-1)" "unprognostic (2.00e-1)" "unprognostic (1.87e-2)" "unprognostic (3.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.08e-2)" "unprognostic (3.92e-2)" "potential prognostic favorable (1.25e-6)" "unprognostic (3.62e-3)" "unprognostic (3.77e-3)" "unprognostic (3.84e-2)" "unprognostic (3.16e-1)" "unprognostic (1.25e-1)" "unprognostic (2.90e-1)" "unprognostic (3.93e-1)" "unprognostic (7.35e-2)" "unprognostic (1.19e-1)" "unprognostic (7.68e-2)" "unprognostic (1.04e-1)" "unprognostic (9.92e-2)" "unprognostic (1.79e-1)" "unprognostic (1.58e-2)" "unprognostic (6.36e-2)" "unprognostic (1.92e-1)" "unprognostic (2.92e-1)" "unprognostic (4.88e-2)" "unprognostic (1.39e-1)" ZBTB20 "DKFZp566F123, DPZF, ODA-8S, ZNF288" ENSG00000181722 "Zinc finger and BTB domain containing 20" Q9HC78 3 114314500-115147292 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "intestine: 1394301.8" "HPA015551, HPA016815" Approved Enhanced "Nucleoplasm,Nuclear bodies" No No "Cluster 32: Basophils - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 25: Non-specific - Transcription" "Cluster 65: Non-specific - Unknown function" "Cluster 7: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies" "HPA015551: , HPA016815: " "potential prognostic favorable (2.83e-4)" "unprognostic (1.99e-1)" "unprognostic (3.65e-1)" "unprognostic (2.14e-1)" "unprognostic (1.68e-1)" "unprognostic (5.67e-2)" "unprognostic (1.00e-1)" "unprognostic (6.11e-2)" "unprognostic (1.42e-1)" "potential prognostic favorable (4.72e-7)" "unprognostic (1.38e-3)" "unprognostic (9.61e-3)" "unprognostic (1.20e-1)" "unprognostic (2.20e-1)" "unprognostic (3.40e-1)" "unprognostic (2.73e-1)" "unprognostic (3.73e-2)" "unprognostic (4.77e-1)" "unprognostic (4.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.33e-1)" "unprognostic (7.27e-3)" "unprognostic (1.28e-1)" "unprognostic (8.03e-2)" "unprognostic (4.94e-2)" "unprognostic (5.67e-2)" ZBTB22 "BING1, fru, fruitless, ZBTB22A, ZNF297, ZNF297A" ENSG00000236104 "Zinc finger and BTB domain containing 22" O15209 6 33314406-33317942 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 3.1;Bergmann glia: 5.4;Brain excitatory neurons: 3.5;Brain inhibitory neurons: 3.4;Choroid plexus epithelial cells: 2.6;Distal convoluted tubule cells: 2.3;Ependymal cells: 9.5;Loop of henle epithelial cells: 2.6;Microglia: 3.8;Oligodendrocyte progenitor cells: 3.6;Oligodendrocytes: 2.8;Other brain neurons: 3.8;Papillary tip epithelial cells: 4.2;Podocytes: 3.6;Proximal tubule cells: 2.5;Renal collecting duct intercalated cells: 2.2;Renal collecting duct principal cells: 3.5;Renal connecting tubule cells: 2.2" "Group enriched" "Detected in some" 6 "Ciliated cells: 9.5;Ductal cells: 3.5;Glial cells: 5.4;Neuronal cells: 3.8;Renal nephron cells: 4.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA043848 Approved Nucleoplasm No No "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 53: Neurons - Mixed function" "Cluster 28: Non-specific - Nuclear processes" "Cluster 98: Neurons - Neurotransmission & signaling" 10 Nucleoplasm "HPA043848: " "unprognostic (2.21e-2)" "unprognostic (2.28e-1)" "unprognostic (3.18e-1)" "potential prognostic unfavorable (2.56e-4)" "unprognostic (6.98e-2)" "unprognostic (1.61e-1)" "unprognostic (2.50e-1)" "unprognostic (3.78e-2)" "unprognostic (1.69e-1)" "unprognostic (1.43e-1)" "unprognostic (1.82e-2)" "unprognostic (9.96e-2)" "unprognostic (1.48e-1)" "unprognostic (8.38e-2)" "unprognostic (2.53e-1)" "unprognostic (2.33e-1)" "unprognostic (3.30e-3)" "unprognostic (2.25e-2)" "unprognostic (3.05e-2)" "unprognostic (2.26e-1)" "unprognostic (8.16e-2)" "unprognostic (1.93e-1)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (1.53e-2)" "unprognostic (3.00e-1)" "unprognostic (1.11e-1)" "unprognostic (1.86e-1)" "unprognostic (2.68e-1)" "unprognostic (2.94e-1)" "unprognostic (9.52e-2)" ZBTB24 "BIF1, KIAA0441, PATZ2, ZNF450" ENSG00000112365 "Zinc finger and BTB domain containing 24" O43167 6 109460632-109483239 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 16.5" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 45.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Spleen - B-cells (Spleen), Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 23889.6;T-cells: 54224.7" "Not detected" "Not detected" "HPA017872, HPA049003" Uncertain Approved "Nucleoplasm,Cytokinetic bridge,Centrosome" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 40: Non-specific - Mixed function" "Cluster 9: Non-specific - Receptor signaling" "Cluster 28: Non-specific - Nuclear processes" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 67 Nucleoplasm "Cytokinetic bridge, Centrosome" "HPA017872: , HPA049003: " "unprognostic (2.44e-2)" "unprognostic (3.09e-2)" "unprognostic (1.38e-1)" "unprognostic (2.70e-2)" "unprognostic (8.34e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-1)" "unprognostic (7.62e-2)" "unprognostic (2.44e-2)" "unprognostic (3.79e-2)" "unprognostic (2.32e-3)" "unprognostic (1.33e-1)" "potential prognostic unfavorable (4.66e-4)" "potential prognostic unfavorable (7.88e-4)" "unprognostic (1.19e-1)" "unprognostic (1.18e-1)" "unprognostic (2.86e-1)" "unprognostic (1.28e-1)" "unprognostic (3.26e-2)" "unprognostic (5.64e-3)" "unprognostic (2.76e-2)" "unprognostic (1.66e-2)" "unprognostic (1.04e-1)" "unprognostic (7.63e-2)" "unprognostic (2.43e-3)" "unprognostic (7.65e-2)" "unprognostic (9.73e-2)" "unprognostic (1.32e-1)" "unprognostic (3.55e-1)" "unprognostic (2.90e-2)" "unprognostic (2.84e-1)" ZBTB38 "CIBZ, FLJ35036, PPP1R171, ZNF921" ENSG00000177311 "Zinc finger and BTB domain containing 38" Q8NAP3 3 141324213-141449792 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Myeloma: 324.3" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 4267742.7;T-cells: 3019282.4" "Tissue enriched" "Detected in single" 6756 "lymphoid tissue: 675583.1" "HPA014865, HPA059378" Enhanced Nucleoplasm No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 34: Non-specific - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 44: Plasma cells - Antibody production & secretion" 8 Nucleoplasm "HPA014865: , HPA059378: " "unprognostic (1.77e-2)" "unprognostic (9.25e-2)" "unprognostic (1.71e-1)" "unprognostic (5.41e-2)" "unprognostic (2.62e-2)" "unprognostic (4.78e-2)" "unprognostic (4.19e-1)" "unprognostic (5.81e-2)" "unprognostic (6.65e-2)" "unprognostic (5.19e-3)" "potential prognostic favorable (5.13e-5)" "unprognostic (1.99e-1)" "unprognostic (1.62e-2)" "unprognostic (9.88e-2)" "unprognostic (2.10e-1)" "unprognostic (6.00e-2)" "unprognostic (5.36e-2)" "unprognostic (2.14e-1)" "unprognostic (2.08e-2)" "unprognostic (6.48e-2)" "unprognostic (9.24e-3)" "unprognostic (3.79e-3)" "unprognostic (1.25e-1)" "unprognostic (2.97e-1)" "unprognostic (2.14e-2)" "unprognostic (4.79e-2)" "unprognostic (2.65e-1)" "unprognostic (2.25e-2)" "unprognostic (1.14e-1)" "unprognostic (8.64e-3)" "unprognostic (2.10e-1)" ZBTB4 "KAISO-L1, KIAA1538, ZNF903" ENSG00000174282 "Zinc finger and BTB domain containing 4" Q9P1Z0 17 7459366-7484263 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 56.9;Bergmann glia: 50.9;Brain excitatory neurons: 49.5;Brain inhibitory neurons: 48.1;Choroid plexus epithelial cells: 111.6;Distal convoluted tubule cells: 50.7;Ependymal cells: 37.5;Loop of henle epithelial cells: 56.9;Microglia: 36.9;Oligodendrocyte progenitor cells: 31.3;Oligodendrocytes: 38.6;Other brain neurons: 49.2;Papillary tip epithelial cells: 40.9;Podocytes: 94.2;Proximal tubule cells: 40.1;Renal collecting duct intercalated cells: 84.3;Renal collecting duct principal cells: 59.2;Renal connecting tubule cells: 57.5" "Group enriched" "Detected in some" 11 "Ciliated cells: 111.6;Ductal cells: 84.3;Glial cells: 56.9;Neuronal cells: 49.5;Renal nephron cells: 94.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Liver - Vascular endothelial cells, Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in some" "bone marrow: 1234836.7;lymphoid tissue: 1789746.5" "CAB008980, HPA064763" Supported Supported "Nucleoplasm,Nuclear bodies,Cytosol" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 74: Non-specific - Signal transduction" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 42: Non-specific - Unknown function" "Cluster 102: Non-specific - Mixed function" 11 "Nuclear bodies" "Nucleoplasm, Cytosol" "CAB008980: , HPA064763: " "unprognostic (2.99e-3)" "unprognostic (4.96e-1)" "unprognostic (1.86e-1)" "unprognostic (1.10e-3)" "unprognostic (1.95e-1)" "unprognostic (2.58e-2)" "unprognostic (6.40e-2)" "unprognostic (2.95e-1)" "unprognostic (3.78e-3)" "unprognostic (1.30e-1)" "validated prognostic favorable (6.23e-9)" "validated prognostic favorable (2.84e-4)" "unprognostic (1.42e-2)" "unprognostic (4.74e-1)" "unprognostic (1.83e-3)" "potential prognostic favorable (2.19e-4)" "unprognostic (3.16e-3)" "unprognostic (1.07e-2)" "unprognostic (9.91e-2)" "potential prognostic unfavorable (6.32e-4)" "unprognostic (3.29e-2)" "unprognostic (5.42e-3)" "unprognostic (5.57e-2)" "unprognostic (1.05e-1)" "unprognostic (5.02e-2)" "unprognostic (4.31e-2)" "unprognostic (2.62e-2)" "unprognostic (1.88e-1)" "unprognostic (1.10e-1)" "unprognostic (1.72e-1)" "unprognostic (1.06e-1)" ZBTB8B "DKFZp547H154, RP1-27O5.1, ZNF916B" ENSG00000273274 "Zinc finger and BTB domain containing 8B" Q8NAP8 1 32465072-32496686 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Adipose visceral - Mesothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA027818, HPA028690, HPA055553, HPA071427" Enhanced Enhanced Nucleoplasm,Cytosol NA NA "Cluster 1: Neurons - Mixed function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 76: Pancreatic endocrine cells - Endocrine signaling" 6 Nucleoplasm Cytosol "HPA027818: , HPA028690: , HPA055553: , HPA071427: " "unprognostic (2.78e-3)" "unprognostic (3.11e-2)" "unprognostic (5.11e-2)" "unprognostic (2.86e-2)" ZBTB9 "MGC23166, ZNF919" ENSG00000213588 "Zinc finger and BTB domain containing 9" Q96C00 6 33453970-33457544 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 15.2" "Cell type enhanced" "Detected in some" "Astrocytes: 2.5;Bergmann glia: 1.5;Brain excitatory neurons: 2.7;Brain inhibitory neurons: 1.4;Choroid plexus epithelial cells: 10.9;Ependymal cells: 6.0;Oligodendrocyte progenitor cells: 1.5;Oligodendrocytes: 1.1;Other brain neurons: 1.9" "Cell type enriched" "Detected in some" 4 "Ciliated cells: 10.9" "Cell type enhanced" "Detected in many" "choroid plexus epithelial cell: 19.5" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in all" "choroid plexus: 20.1" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 1150 "Granulosa cells: 114975.9" "Not detected" "Not detected" "HPA036767, HPA058171" Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" NA NA "Cluster 46: Basophils - Proteolysis" "Cluster 20: Pituitary gland - Hormone signaling" "Cluster 23: Choroid plexus - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 37 Nucleoplasm "Nuclear membrane, Cytosol" "HPA036767: , HPA058171: " "unprognostic (9.68e-2)" "unprognostic (6.99e-2)" "unprognostic (5.84e-2)" "unprognostic (3.02e-2)" "unprognostic (5.69e-2)" "unprognostic (1.48e-2)" "unprognostic (9.90e-2)" "unprognostic (1.88e-2)" "unprognostic (2.56e-3)" "unprognostic (4.01e-1)" "potential prognostic unfavorable (3.34e-4)" "unprognostic (2.96e-2)" "unprognostic (1.45e-1)" "unprognostic (6.95e-2)" "unprognostic (5.02e-2)" "unprognostic (1.26e-1)" "unprognostic (1.71e-1)" "unprognostic (2.42e-1)" "unprognostic (2.16e-2)" "unprognostic (1.86e-1)" "unprognostic (3.76e-1)" "unprognostic (3.11e-1)" "unprognostic (4.65e-2)" ZC2HC1C "C14orf140, FAM164C" ENSG00000119703 "Zinc finger C2HC-type containing 1C" Q53FD0 14 75064109-75119502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 22.6;testis: 51.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 302.0;Early spermatids: 118.3;Epicardial cells: 161.5;Late primary spermatocytes: 437.9;Late spermatids: 280.2;Myonuclei: 189.9" "Cell type enhanced" "Detected in all" "Barrier epithelial cells: 161.5;Myocytes: 302.0;Spermatogenic cell types: 437.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Heart muscle - Cardiomyocytes, Lung - Respiratory ciliated cells, Testis - Early spermatids, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 3647 "salivary gland: 364709.6" "HPA050928, HPA065062" Enhanced Approved "Nuclear speckles,Mitochondria" No No "Cluster 22: Epididymis - Mixed function" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 19 "Nuclear speckles" Mitochondria "HPA050928: , HPA065062: " "unprognostic (5.07e-2)" "unprognostic (3.65e-1)" "unprognostic (9.35e-3)" "unprognostic (1.79e-1)" "unprognostic (3.70e-2)" "unprognostic (2.50e-3)" "unprognostic (9.68e-3)" "unprognostic (6.39e-2)" "validated prognostic favorable (4.67e-10)" "validated prognostic favorable (9.59e-4)" "unprognostic (4.47e-2)" "unprognostic (7.40e-2)" "unprognostic (1.09e-2)" "unprognostic (1.10e-1)" "unprognostic (9.06e-3)" "unprognostic (7.79e-2)" "unprognostic (2.52e-1)" "unprognostic (8.67e-2)" "potential prognostic favorable (2.77e-4)" "unprognostic (3.52e-1)" "unprognostic (1.39e-1)" "unprognostic (1.66e-1)" "unprognostic (2.76e-3)" "unprognostic (1.90e-1)" "unprognostic (1.02e-2)" "unprognostic (2.78e-1)" "unprognostic (3.02e-1)" "unprognostic (1.26e-1)" ZC3H12A "FLJ23231, MCPIP1, Regnase-1" ENSG00000163874 "Zinc finger CCCH-type containing 12A" Q5D1E8 1 37474580-37484377 "Disease related genes, Predicted intracellular proteins" "Angiogenesis, Antiviral defense, Apoptosis, Differentiation, DNA damage, Host-virus interaction, Immunity, Inflammatory response, Neurogenesis, Stress response, Transcription, Transcription regulation" "Developmental protein, DNA-binding, Endonuclease, Hydrolase, Nuclease, Repressor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 128.7" "Cell type enhanced" "Detected in many" "Breast secretory cells: 222.6;Endometrial secretory cells: 242.8;Epididymal basal cells: 350.2;Epididymal clear cells: 224.5;Fallopian secretory cells: 146.3" "Cell type enhanced" "Detected in many" "Basal cells: 350.2;Secretory cells: 242.8" "Cell type enhanced" "Detected in some" "astrocyte: 4.2;endothelial cell: 5.0;leukocyte: 10.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Neutrophils, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate glandular cells, Testis - Late spermatids" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Macrophages: 1324818.3;T-cells: 814544.4" "Tissue enriched" "Detected in single" 2570 "lymphoid tissue: 256958.7" "HPA032052, HPA032053" Uncertain Supported "Nucleoplasm,Cytoplasmic bodies" No No "Cluster 7: Non-specific - Innate immune response" "Cluster 11: Esophagus - Basic cellular processes" "Cluster 12: Non-specific - Vasculature" "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 20: Non-specific - Transcription regulation" 24 "Cytoplasmic bodies" Nucleoplasm "HPA032052: , HPA032053: " "unprognostic (7.09e-2)" "unprognostic (2.05e-2)" "unprognostic (1.86e-1)" "unprognostic (1.36e-3)" "unprognostic (1.19e-3)" "unprognostic (1.45e-1)" "unprognostic (8.32e-3)" "unprognostic (1.83e-2)" "unprognostic (2.53e-1)" "unprognostic (2.95e-1)" "unprognostic (4.82e-3)" "unprognostic (2.35e-2)" "unprognostic (2.90e-2)" "unprognostic (7.35e-2)" "unprognostic (1.91e-2)" "unprognostic (1.27e-2)" "unprognostic (7.12e-2)" "unprognostic (7.00e-2)" "unprognostic (2.41e-1)" "unprognostic (8.87e-3)" "unprognostic (2.97e-2)" "unprognostic (8.98e-3)" "unprognostic (2.41e-2)" "unprognostic (2.21e-2)" "unprognostic (5.69e-2)" "unprognostic (6.01e-2)" "unprognostic (2.26e-1)" "unprognostic (1.94e-2)" "unprognostic (4.43e-2)" "unprognostic (4.77e-1)" "unprognostic (1.46e-1)" ZC3H7B "DKFZp434K0920, FLJ13787, KIAA1031, RoXaN" ENSG00000100403 "Zinc finger CCCH-type containing 7B" Q9UGR2 22 41301525-41360147 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 3712232.3;Neutrophils: 3774829.6" "Low tissue specificity" "Detected in many" "HPA001784, HPA076092" Uncertain Uncertain Cytosol NA NA "Cluster 4: Adrenal gland - Steroid metabolism" "Cluster 24: Neurons - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 18: Adrenal cortex cells - Steroidogensis" 2 Cytosol "HPA001784: , HPA076092: " "unprognostic (4.81e-2)" "unprognostic (9.41e-2)" "unprognostic (5.43e-2)" "unprognostic (1.11e-2)" "unprognostic (5.10e-3)" "unprognostic (7.18e-2)" "unprognostic (6.04e-2)" "unprognostic (3.85e-2)" "unprognostic (2.18e-1)" "unprognostic (6.38e-2)" "potential prognostic favorable (2.30e-6)" "unprognostic (1.22e-3)" "unprognostic (2.48e-3)" "unprognostic (7.92e-3)" "unprognostic (2.43e-1)" "unprognostic (2.65e-1)" "unprognostic (1.62e-1)" "unprognostic (4.06e-1)" "potential prognostic favorable (3.97e-5)" "unprognostic (2.02e-1)" "unprognostic (4.79e-1)" "unprognostic (3.44e-2)" "unprognostic (1.05e-1)" "unprognostic (3.09e-1)" "unprognostic (8.39e-3)" "unprognostic (4.19e-2)" "unprognostic (4.01e-1)" "unprognostic (3.15e-2)" "unprognostic (3.46e-1)" "unprognostic (8.82e-2)" "unprognostic (2.62e-3)" ZC4H2 "HCA127, KIAA1166, MCS, MRXS4, WWS" ENSG00000126970 "Zinc finger C4H2-type containing" Q9NQZ6 X 64915802-65034713 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 190.7;Cone photoreceptor cells: 126.3;Gonadotrophs: 129.9;Somatotrophs: 125.2" "Cell type enhanced" "Detected in all" "Ciliated cells: 190.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Kidney - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 92 "Granulosa cells: 7966.1;Neurons: 10485.8" "Not detected" "Not detected" HPA049584 Approved Approved "Vesicles,Microtubules,Primary cilium,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 49: Hindbrain - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 7: Non-specific - Transcription" 18 "Vesicles, Microtubules, Primary cilium" "Basal body" "HPA049584: " "unprognostic (1.51e-3)" "unprognostic (2.07e-2)" "unprognostic (3.82e-2)" "unprognostic (9.19e-3)" "unprognostic (6.70e-2)" "unprognostic (5.27e-2)" "unprognostic (4.77e-2)" "potential prognostic favorable (1.28e-4)" "unprognostic (7.72e-2)" "unprognostic (1.23e-1)" "potential prognostic favorable (3.53e-5)" "unprognostic (2.17e-2)" "unprognostic (3.54e-2)" "unprognostic (1.98e-3)" "unprognostic (1.24e-2)" "unprognostic (1.09e-1)" "unprognostic (5.92e-3)" "unprognostic (2.01e-3)" "unprognostic (2.32e-2)" "unprognostic (1.12e-1)" "unprognostic (3.22e-1)" "unprognostic (3.24e-2)" "unprognostic (2.53e-1)" "unprognostic (5.67e-2)" "unprognostic (3.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-1)" "unprognostic (9.10e-2)" "potential prognostic unfavorable (9.61e-4)" "unprognostic (4.80e-2)" ZDBF2 "FLJ45338, KIAA1571" ENSG00000204186 "Zinc finger DBF-type containing 2" Q9HCK1 2 206274663-206314427 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Brain excitatory neurons: 86.5;Brain inhibitory neurons: 117.1;Choroid plexus epithelial cells: 413.8;Ependymal cells: 52.4;Oligodendrocyte progenitor cells: 42.0;Other brain neurons: 91.5;Podocytes: 44.9" "Group enriched" "Detected in many" 5 "Ciliated cells: 413.8;Neuronal cells: 117.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "testis cancer: 9.2" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "Cell type enriched" "Detected in single" 636 "Neurons: 63630.8" "Tissue enriched" "Detected in single" 354 "skin: 35438.7" "HPA039121, HPA050311" Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 64: Non-specific - Transcription" "Cluster 23: Choroid plexus - Mixed function" "Cluster 51: Myeloma - Immunoglobulins" "Cluster 101: Choroid plexus epithelial cells - Ion transport" 8 Nucleoplasm Cytosol "HPA039121: , HPA050311: " "unprognostic (3.75e-2)" "unprognostic (1.17e-2)" "unprognostic (4.01e-2)" "unprognostic (1.71e-1)" "potential prognostic favorable (9.67e-4)" "potential prognostic unfavorable (3.81e-4)" "unprognostic (2.68e-1)" "unprognostic (3.79e-2)" ZDHHC1 "C16orf1, HSU90653, ZNF377" ENSG00000159714 "Zinc finger DHHC-type containing 1" Q8WTX9 16 67394152-67416833 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 132.9;Endometrial ciliated cells: 107.5;Epididymal efferent duct ciliated cells: 87.3;Fallopian tube ciliated cells: 107.4;Late primary spermatocytes: 168.8;Late spermatids: 305.8;Respiratory ciliated cells: 149.7" "Group enriched" "Detected in many" 6 "Ciliated cells: 149.7;Spermatogenic cell types: 305.8" "Cell type enhanced" "Detected in all" "ependymal cell: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.4;non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 502 "Fallopian tube cells: 50210.6" "Not detected" "Not detected" "HPA042531, HPA048659" Uncertain Approved Cytosol NA NA "Cluster 40: Monocytes - Innate immune response" "Cluster 21: Testis - Mixed function" "Cluster 17: Choroid plexus - Cilium" "Cluster 27: Breast cancer - Unknown function" "Cluster 107: Ciliated cells - Cilia assembly & function" 14 Cytosol "HPA042531: , HPA048659: " "unprognostic (1.63e-3)" "unprognostic (9.43e-2)" "unprognostic (2.78e-2)" "unprognostic (1.54e-1)" "unprognostic (4.23e-2)" "unprognostic (7.09e-3)" "unprognostic (3.58e-2)" "unprognostic (2.69e-2)" "unprognostic (1.89e-1)" "unprognostic (3.35e-3)" "unprognostic (3.72e-2)" "unprognostic (1.95e-2)" "unprognostic (2.99e-2)" "unprognostic (1.08e-1)" "unprognostic (2.69e-1)" "unprognostic (1.24e-2)" "unprognostic (2.77e-1)" "unprognostic (1.28e-1)" "unprognostic (1.11e-1)" "unprognostic (1.32e-1)" "unprognostic (3.23e-1)" "unprognostic (2.26e-3)" "unprognostic (1.05e-1)" "unprognostic (2.19e-1)" "unprognostic (1.91e-2)" "unprognostic (1.12e-1)" "unprognostic (2.07e-1)" "unprognostic (1.13e-1)" "unprognostic (9.64e-2)" "unprognostic (5.08e-2)" "unprognostic (3.29e-2)" ZDHHC12 "FLJ14524, ZNF400" ENSG00000160446 "Zinc finger DHHC-type palmitoyltransferase 12" Q96GR4 9 128720870-128724127 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Colonocytes: 151.0;Cytotrophoblasts: 215.2;Enterocytes: 162.6;Esophageal apical cells: 228.5;Esophageal basal cells: 190.2;Esophageal suprabasal cells: 222.8;Extravillous trophoblasts: 286.1;Hofbauer cells: 151.2;Migrating cytotrophoblasts: 187.7" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 228.5;Trophoblast cells: 286.1" "Cell type enhanced" "Detected in many" "leukocyte: 13.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Spleen - Neutrophils_2, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA059339 Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 22: Eosinophils - Transcription" "Cluster 60: Stomach - Digestion" "Cluster 20: Macrophages & Microglia - Immune response" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 63: Cytotrophoblasts - Basic cellular functions" Nucleoplasm "Intermediate filaments" "HPA059339: " "unprognostic (1.23e-3)" "unprognostic (1.02e-1)" "unprognostic (1.81e-1)" "unprognostic (3.69e-2)" "unprognostic (4.87e-1)" "unprognostic (6.45e-2)" "potential prognostic unfavorable (3.94e-4)" "unprognostic (4.11e-2)" "unprognostic (4.86e-2)" "unprognostic (2.46e-1)" "unprognostic (7.61e-2)" "unprognostic (1.03e-2)" "unprognostic (2.45e-2)" "unprognostic (3.31e-3)" "potential prognostic unfavorable (3.93e-5)" "unprognostic (1.82e-2)" "unprognostic (2.15e-1)" "unprognostic (7.78e-3)" "unprognostic (2.26e-1)" "unprognostic (8.18e-2)" "unprognostic (3.42e-2)" "unprognostic (2.83e-1)" "unprognostic (3.27e-1)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (1.44e-1)" "unprognostic (1.86e-2)" "unprognostic (5.26e-2)" "unprognostic (1.36e-1)" "unprognostic (3.31e-2)" "unprognostic (1.54e-1)" ZDHHC13 "FLJ10852, FLJ10941, HIP14L" ENSG00000177054 "Zinc finger DHHC-type palmitoyltransferase 13" Q8IUH4 11 19117099-19176422 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 189.3;Esophageal apical cells: 487.7;Neutrophil progenitors: 172.3" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 487.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Heart muscle - Macrophages, Liver - Vascular endothelial cells, Testis - Early spermatids, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enhanced" "Detected in many" "bone marrow: 1212496.0;fallopian tube: 1287936.1" "HPA016759, HPA018791" Uncertain Approved "Golgi apparatus,Vesicles" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 3: Rhabdoid - Membrane components" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 21 Vesicles "Golgi apparatus" "HPA016759: , HPA018791: " "unprognostic (2.46e-1)" "unprognostic (1.02e-2)" "unprognostic (5.44e-2)" "unprognostic (2.76e-1)" "unprognostic (9.43e-2)" "unprognostic (1.06e-1)" "unprognostic (6.86e-3)" "unprognostic (4.70e-2)" "unprognostic (7.14e-2)" "unprognostic (8.19e-2)" "potential prognostic favorable (6.30e-6)" "unprognostic (3.16e-1)" "unprognostic (1.96e-1)" "unprognostic (2.60e-2)" "unprognostic (3.67e-2)" "unprognostic (3.88e-1)" "unprognostic (7.39e-2)" "unprognostic (2.01e-1)" "unprognostic (2.70e-1)" "unprognostic (3.89e-1)" "unprognostic (1.96e-3)" "unprognostic (1.20e-1)" "unprognostic (1.40e-2)" "unprognostic (3.89e-1)" "unprognostic (3.74e-2)" "unprognostic (3.91e-2)" "unprognostic (8.15e-2)" "unprognostic (3.66e-2)" "unprognostic (5.27e-2)" "unprognostic (1.25e-1)" "unprognostic (3.56e-1)" ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity, Lipid transport, Transport" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 155.9" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 155.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Keratinocyte (other), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Keratinocytes: 1492037.3" "Tissue enriched" "Detected in many" "skeletal muscle: 9961475.9" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 41: Basophils - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 38: Sub-cortical - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 100: Stratified epithelial cells - Barrier functions" 8 "Nucleoplasm, Plasma membrane" "HPA014670: " "unprognostic (3.98e-1)" "unprognostic (3.93e-2)" "unprognostic (1.29e-1)" "unprognostic (3.02e-3)" "unprognostic (7.02e-2)" "unprognostic (1.10e-2)" "unprognostic (9.67e-2)" "unprognostic (4.84e-2)" "unprognostic (2.79e-2)" "unprognostic (3.32e-3)" "potential prognostic favorable (2.64e-7)" "unprognostic (4.09e-3)" "unprognostic (4.76e-1)" "unprognostic (1.05e-1)" "unprognostic (2.07e-1)" "unprognostic (9.97e-3)" "potential prognostic unfavorable (2.65e-4)" "unprognostic (2.19e-1)" "unprognostic (2.57e-1)" "unprognostic (4.95e-2)" "unprognostic (7.66e-2)" "potential prognostic unfavorable (2.06e-4)" "unprognostic (8.08e-2)" "unprognostic (9.84e-2)" "unprognostic (2.03e-2)" "unprognostic (2.53e-1)" "unprognostic (1.10e-1)" "unprognostic (2.17e-1)" "unprognostic (2.63e-1)" "unprognostic (8.02e-2)" "unprognostic (3.35e-1)" ZDHHC7 "DHHC7, FLJ10792, FLJ20279, SERZ-B, SERZ1, ZNF370" ENSG00000153786 "Zinc finger DHHC-type palmitoyltransferase 7" Q9NXF8 16 84974175-85011535 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Breast - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019215, HPA059054, HPA059642" Uncertain Supported "Golgi apparatus" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 68: Non-specific - Cell cycle regulation" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" "Golgi apparatus" "HPA019215: , HPA059054: , HPA059642: " "unprognostic (4.26e-2)" "unprognostic (1.12e-1)" "unprognostic (4.54e-2)" "unprognostic (1.38e-2)" "unprognostic (7.24e-2)" "unprognostic (1.01e-1)" "unprognostic (3.19e-1)" "unprognostic (4.63e-2)" "unprognostic (8.89e-2)" "unprognostic (2.30e-1)" "unprognostic (1.23e-1)" "unprognostic (5.01e-2)" "potential prognostic favorable (7.19e-4)" "potential prognostic unfavorable (9.94e-5)" "unprognostic (6.92e-2)" "unprognostic (1.56e-1)" "unprognostic (3.11e-2)" "potential prognostic unfavorable (2.43e-4)" "unprognostic (1.86e-1)" "unprognostic (5.22e-3)" "unprognostic (1.43e-1)" "unprognostic (1.65e-2)" "unprognostic (3.02e-2)" "unprognostic (7.41e-2)" "unprognostic (5.05e-2)" "unprognostic (5.56e-2)" "unprognostic (1.83e-1)" "unprognostic (2.39e-1)" "unprognostic (2.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.58e-3)" ZDHHC8 "DHHC8, KIAA1292, ZNF378" ENSG00000099904 "Zinc finger DHHC-type palmitoyltransferase 8" Q9ULC8 22 20129456-20148007 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Host-virus interaction" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epididymal principal cells: 56.5" "Cell type enhanced" "Detected in many" "Reproductive supporting cells: 56.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 54 "Microglia and Neuropil: 5429.6" "Tissue enriched" "Detected in single" 46 "cerebral cortex: 4585.1" HPA003422 Uncertain Approved Nucleoplasm,Cytosol NA NA "Cluster 41: Basophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 66: Non-specific - Mitochondria" "Cluster 10: Epididymal principal cells - Sperm maturation microenvironment" 2 Cytosol Nucleoplasm "HPA003422: " "unprognostic (1.61e-1)" "unprognostic (3.51e-2)" "unprognostic (4.53e-1)" "unprognostic (1.74e-2)" "unprognostic (1.31e-1)" "unprognostic (3.91e-2)" "unprognostic (1.25e-1)" "unprognostic (2.21e-1)" "unprognostic (1.53e-1)" "unprognostic (2.41e-1)" "unprognostic (2.62e-1)" "unprognostic (1.95e-1)" "unprognostic (1.05e-2)" "unprognostic (5.47e-2)" "unprognostic (1.78e-2)" "unprognostic (1.55e-1)" "unprognostic (1.69e-1)" "unprognostic (2.52e-1)" "unprognostic (7.86e-2)" "unprognostic (1.96e-2)" "unprognostic (1.85e-1)" "unprognostic (6.19e-2)" "unprognostic (1.60e-3)" "unprognostic (1.52e-1)" "unprognostic (3.47e-3)" "potential prognostic favorable (6.45e-4)" "unprognostic (2.18e-1)" "unprognostic (1.55e-1)" "unprognostic (2.51e-1)" "unprognostic (1.36e-2)" "unprognostic (4.58e-2)" ZFAND2B AIRAPL ENSG00000158552 "Zinc finger AN1-type containing 2B" Q8WV99 2 219195237-219209651 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Colonocytes: 116.2;Enterocytes: 158.9;Esophageal apical cells: 290.5;Platelets: 145.5" "Cell type enhanced" "Detected in all" "Apical squamous epithelial cells: 290.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enhanced" "Detected in many" "cerebral cortex: 1017753.6" "HPA035159, HPA035160" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Nuclear bodies,Primary cilium,Primary cilium tip,Basal body,Cytosol" NA NA "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 45: Colonocytes & Enterocytes - Gastrointestinal absorption & barrier" 18 "Nucleoli, Nucleoli rim" "Nucleoplasm, Nuclear bodies, Primary cilium, Primary cilium tip, Basal body, Cytosol" "HPA035159: , HPA035160: " "unprognostic (1.49e-1)" "unprognostic (3.37e-3)" "unprognostic (7.70e-2)" "unprognostic (2.06e-1)" "unprognostic (1.01e-1)" "unprognostic (1.89e-1)" "unprognostic (1.99e-1)" "unprognostic (1.29e-3)" "unprognostic (5.00e-2)" "unprognostic (5.58e-2)" "unprognostic (3.80e-3)" "unprognostic (3.27e-3)" "potential prognostic favorable (3.27e-4)" "unprognostic (2.38e-3)" "unprognostic (2.23e-2)" "unprognostic (3.97e-2)" "unprognostic (1.47e-1)" "unprognostic (1.36e-2)" "unprognostic (6.10e-2)" "unprognostic (2.65e-1)" "unprognostic (1.91e-1)" "unprognostic (4.62e-2)" "unprognostic (4.44e-1)" "unprognostic (1.35e-1)" "unprognostic (1.95e-1)" "unprognostic (2.24e-2)" "unprognostic (2.90e-1)" "unprognostic (2.25e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-2)" "unprognostic (2.77e-1)" ZFHX2 "KIAA1056, KIAA1762, ZFH-5, ZNF409" ENSG00000136367 "Zinc finger homeobox 2" Q9C0A1 14 23520857-23556192 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 6.6" "Cell type enhanced" "Detected in many" "Early spermatids: 86.2;Ependymal cells: 137.0;Late primary spermatocytes: 63.2;Late spermatids: 79.8;Podocytes: 85.9;Respiratory ciliated cells: 150.6;Retinal amacrine cells: 81.0;Retinal bipolar cells: 195.6" "Cell type enhanced" "Detected in many" "Ciliated cells: 150.6;Neuronal cells: 195.6;Renal nephron cells: 85.9;Spermatogenic cell types: 86.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Neuroblastoma: 4.5" "Lung - Respiratory ciliated cells, Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1254 "Microglia and Neuropil: 72363.0;Neurons: 178466.3" "Not detected" "Not detected" "HPA000720, HPA005146" Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center" Yes No "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 2 "Nucleoli fibrillar center" Nucleoplasm "HPA000720: , HPA005146: " "potential prognostic favorable (3.01e-4)" "unprognostic (1.14e-1)" "unprognostic (3.12e-1)" "unprognostic (7.60e-2)" "unprognostic (2.87e-1)" "unprognostic (2.13e-1)" "unprognostic (2.52e-1)" "unprognostic (6.04e-2)" "unprognostic (3.57e-2)" "unprognostic (2.10e-1)" "unprognostic (6.72e-2)" "unprognostic (2.27e-1)" "unprognostic (1.88e-1)" ZFP37 ZNF906 ENSG00000136866 "ZFP37 zinc finger protein" Q9Y6Q3 9 113038377-113056759 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Lactotrophs: 39.4;Oligodendrocyte progenitor cells: 26.1;Retinal amacrine cells: 26.7;Retinal bipolar cells: 38.2;Retinal pigment epithelial cells: 25.6;Somatotrophs: 32.0" "Cell type enhanced" "Detected in many" "Neuronal cells: 38.2;Pituitary endocrine cells: 39.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 2.4" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 149 "Granulosa cells: 22755.0;Neurons: 7015.6" "Not detected" "Not detected" HPA049112 Uncertain Approved Nucleoplasm,Vesicles Yes No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 65: Brain - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" Nucleoplasm Vesicles "HPA049112: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (2.23e-1)" "unprognostic (1.13e-2)" "unprognostic (3.52e-1)" "unprognostic (2.66e-2)" "unprognostic (9.89e-3)" "unprognostic (1.69e-1)" "validated prognostic favorable (2.55e-5)" "validated prognostic favorable (2.73e-4)" "unprognostic (1.38e-1)" "unprognostic (8.06e-2)" "unprognostic (2.50e-1)" "unprognostic (1.31e-1)" "unprognostic (4.72e-2)" "unprognostic (2.91e-1)" "unprognostic (4.80e-2)" "unprognostic (2.54e-1)" "unprognostic (1.04e-1)" "unprognostic (1.18e-1)" "unprognostic (4.49e-3)" "unprognostic (7.31e-2)" "unprognostic (4.01e-1)" "unprognostic (2.34e-2)" "unprognostic (1.87e-1)" "unprognostic (1.87e-1)" "unprognostic (1.47e-1)" ZFP41 "FLJ00028, FLJ38705, ZNF753" ENSG00000181638 "ZFP41 zinc finger protein" Q8N8Y5 8 143246821-143262705 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 6.3;Bergmann glia: 6.0;Brain excitatory neurons: 5.1;Brain inhibitory neurons: 4.8;Choroid plexus epithelial cells: 10.3;Ependymal cells: 11.5;Microglia: 6.3;Oligodendrocyte progenitor cells: 4.0;Oligodendrocytes: 7.6;Other brain neurons: 5.7" "Group enriched" "Detected in some" 4 "Ciliated cells: 11.5;Glial cells: 7.6;Neuronal cells: 5.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 40: Non-specific - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 7 "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: " "unprognostic (5.07e-2)" "unprognostic (3.54e-2)" "unprognostic (6.98e-3)" "unprognostic (2.02e-2)" "unprognostic (1.18e-2)" "unprognostic (1.26e-1)" "unprognostic (2.92e-1)" "unprognostic (6.93e-2)" "unprognostic (1.22e-1)" "unprognostic (2.09e-2)" "unprognostic (2.62e-3)" "unprognostic (2.60e-2)" "unprognostic (1.56e-1)" "potential prognostic unfavorable (7.42e-4)" "unprognostic (3.85e-2)" "unprognostic (1.33e-1)" "unprognostic (7.16e-2)" "unprognostic (5.72e-2)" "unprognostic (7.54e-3)" "unprognostic (1.27e-1)" "unprognostic (9.45e-2)" "unprognostic (8.52e-3)" "unprognostic (3.81e-3)" "unprognostic (1.26e-1)" "unprognostic (1.31e-1)" "unprognostic (1.01e-1)" "unprognostic (5.14e-2)" "unprognostic (7.59e-2)" "unprognostic (1.92e-1)" "potential prognostic unfavorable (4.34e-4)" "unprognostic (2.93e-1)" ZFP91 "PZF, ZNF757" ENSG00000186660 "ZFP91 zinc finger protein, atypical E3 ubiquitin ligase" Q96JP5 11 58579063-58621550 "Enzymes, Predicted intracellular proteins, Transcription factors" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 6.6;Endometrial secretory cells: 5.2;Late primary spermatocytes: 7.6;Late spermatids: 12.5;Parietal cells: 5.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 12.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Group enriched" "Detected in many" "intestine: 4600725.3;lung: 4026220.2;lymphoid tissue: 7561155.8;Stomach: 2654778.8" "HPA024037, CAB025417, HPA065325, HPA074591" Enhanced Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 19 "Nucleoplasm, Nucleoli" "CAB025417: , HPA024037: , HPA065325: , HPA074591: " "unprognostic (6.77e-3)" "unprognostic (9.91e-2)" "unprognostic (3.05e-1)" "unprognostic (8.77e-3)" "unprognostic (1.37e-1)" "unprognostic (2.02e-1)" "unprognostic (6.39e-2)" "unprognostic (5.15e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (4.13e-5)" "potential prognostic favorable (1.52e-6)" "unprognostic (5.32e-3)" "unprognostic (2.85e-1)" "unprognostic (2.01e-2)" "unprognostic (6.13e-2)" "unprognostic (2.22e-2)" "unprognostic (2.14e-2)" "unprognostic (3.22e-2)" "unprognostic (3.27e-1)" "unprognostic (2.63e-2)" "unprognostic (3.68e-3)" "potential prognostic unfavorable (2.10e-5)" "unprognostic (7.74e-2)" "unprognostic (6.68e-2)" "unprognostic (2.22e-2)" "unprognostic (1.48e-1)" "unprognostic (6.72e-2)" "unprognostic (2.44e-1)" "unprognostic (3.81e-2)" "unprognostic (1.25e-1)" "unprognostic (1.41e-1)" ZFPM1 "FOG, FOG1, ZC2HC11A, ZNF89A" ENSG00000179588 "Zinc finger protein, FOG family member 1" Q8IX07 16 88453280-88537031 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Erythrocyte progenitors: 176.6;Megakaryocyte progenitors: 191.2;Megakaryocyte-Erythroid progenitors: 140.8;Megakaryocytes: 111.3" "Cell type enhanced" "Detected in many" "Erythrocytes: 176.6;Megakaryocytes: 191.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Stomach Adenocarcinoma (TCGA): 23.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Pituitary gland - Corticotropes, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 22 "lymphoid tissue: 2237.7" "HPA030495, HPA046603" Enhanced Approved Nucleoplasm NA NA "Cluster 70: Non-specific - Protein processing" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 47: Leukemia - Hemostasis" "Cluster 66: Erythroid cells - Erythroid differentiation and maturation" 7 Nucleoplasm "HPA030495: , HPA046603: " "unprognostic (1.08e-1)" "unprognostic (2.70e-1)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (4.77e-1)" "unprognostic (3.56e-2)" "unprognostic (2.01e-1)" "unprognostic (5.18e-2)" "unprognostic (2.16e-1)" "unprognostic (5.81e-3)" "unprognostic (9.65e-2)" "potential prognostic favorable (2.71e-5)" "unprognostic (9.91e-3)" "unprognostic (5.74e-2)" "unprognostic (2.54e-1)" "unprognostic (6.44e-2)" "unprognostic (1.90e-1)" "unprognostic (7.19e-2)" "unprognostic (1.61e-1)" "unprognostic (4.89e-2)" "unprognostic (5.44e-3)" "unprognostic (1.72e-1)" "unprognostic (1.19e-1)" "unprognostic (1.17e-1)" "unprognostic (1.92e-1)" "unprognostic (5.88e-2)" "unprognostic (2.16e-1)" "unprognostic (2.92e-1)" ZFX ZNF926 ENSG00000005889 "Zinc finger protein X-linked" P17010 X 24149173-24216255 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gonadotrophs: 283.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001748, HPA003877, HPA071863" Supported Approved Nucleoplasm,Nucleoli NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 36: Non-specific - mRNA processing" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" Nucleoplasm Nucleoli "HPA001748: , HPA003877: , HPA071863: " "unprognostic (4.78e-2)" "unprognostic (8.75e-2)" "unprognostic (2.21e-1)" "unprognostic (7.47e-2)" "unprognostic (2.10e-2)" "unprognostic (4.74e-2)" "unprognostic (2.98e-1)" "unprognostic (1.38e-1)" "unprognostic (2.82e-1)" "unprognostic (9.23e-3)" "potential prognostic favorable (4.90e-4)" "unprognostic (7.87e-3)" "unprognostic (1.18e-1)" "unprognostic (1.95e-2)" "unprognostic (9.59e-2)" "unprognostic (3.83e-1)" "unprognostic (2.01e-3)" "unprognostic (1.35e-1)" "unprognostic (2.20e-2)" "unprognostic (2.09e-1)" "unprognostic (6.11e-2)" "unprognostic (1.01e-1)" "unprognostic (9.72e-2)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (7.85e-2)" "unprognostic (3.41e-2)" "unprognostic (1.48e-1)" "unprognostic (2.58e-1)" "unprognostic (1.10e-1)" "unprognostic (2.16e-1)" ZFY ZNF911 ENSG00000067646 "Zinc finger protein Y-linked" P08048 Y 2935281-2982506 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 80.7;Late spermatids: 162.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 162.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Adrenocortical cancer: 12.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA001748, HPA071863" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 44: Bone marrow - Nuclear processes" "Cluster 16: Non-specific - Transcription" "Cluster 47: Leukemia - Hemostasis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 5 Nucleoplasm Nucleoli "HPA001748: , HPA071863: " "unprognostic (4.76e-1)" "unprognostic (5.79e-2)" "unprognostic (1.04e-1)" "unprognostic (1.45e-1)" "unprognostic (5.31e-2)" "potential prognostic favorable (8.16e-5)" "unprognostic (2.87e-1)" "unprognostic (1.31e-3)" "unprognostic (8.67e-2)" "unprognostic (1.41e-2)" "unprognostic (2.40e-1)" "unprognostic (1.25e-1)" "unprognostic (7.34e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-2)" "unprognostic (9.95e-2)" "unprognostic (3.72e-1)" "unprognostic (4.25e-2)" "unprognostic (1.99e-3)" "unprognostic (4.52e-2)" "unprognostic (3.16e-2)" "unprognostic (3.05e-1)" "unprognostic (5.83e-2)" ZFYVE16 "KIAA0305, PPP1R69" ENSG00000039319 "Zinc finger FYVE-type containing 16" Q7Z3T8 5 80408013-80483379 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 483.1;Oligodendrocytes: 871.5" "Cell type enhanced" "Detected in all" "Glial cells: 871.5;Neutrophils: 483.1" "Cell type enhanced" "Detected in all" "oligodendrocyte: 1128.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 21.3;neutrophil: 21.4" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 1390321.0" "Tissue enhanced" "Detected in many" "fallopian tube: 1651871.1" "HPA035935, HPA035936" Supported Enhanced Vesicles,Cytosol No No "Cluster 35: Neutrophils - Protein binding" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 9: Skin cancer - Melanin biosynthesis" "Cluster 40: Monocytes & Neutrophils - Inflammatory signaling" 17 "Vesicles, Cytosol" "HPA035935: , HPA035936: " "unprognostic (7.71e-3)" "unprognostic (6.13e-2)" "unprognostic (1.66e-1)" "unprognostic (3.70e-1)" "unprognostic (6.57e-2)" "unprognostic (3.01e-1)" "unprognostic (8.23e-2)" "unprognostic (8.17e-2)" "unprognostic (2.44e-2)" "unprognostic (2.77e-3)" "potential prognostic favorable (1.62e-7)" "unprognostic (3.16e-3)" "unprognostic (2.37e-1)" "unprognostic (1.81e-1)" "unprognostic (8.31e-2)" "unprognostic (2.72e-1)" "unprognostic (1.31e-1)" "unprognostic (1.04e-2)" "unprognostic (4.59e-2)" "unprognostic (2.71e-1)" "potential prognostic unfavorable (2.78e-4)" "unprognostic (1.42e-2)" "unprognostic (5.51e-3)" "unprognostic (1.99e-1)" "unprognostic (3.62e-2)" "unprognostic (6.06e-2)" "unprognostic (2.48e-1)" "unprognostic (6.55e-2)" "unprognostic (2.00e-1)" "unprognostic (4.90e-3)" "unprognostic (6.48e-2)" ZHX1 ENSG00000165156 "Zinc fingers and homeoboxes 1" Q9UKY1 8 123248451-123275541 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 11.3;Late spermatids: 13.8" "Cell type enhanced" "Detected in many" "Myocytes: 11.3;Spermatogenic cell types: 13.8" "Low cell type specificity" "Detected in some" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Liver - Hepatocytes, Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 753766.9" "Tissue enriched" "Detected in single" 25014 "bone marrow: 2501425.0" HPA055357 Supported Nucleoplasm No No "Cluster 33: Non-specific - ATP binding" "Cluster 76: Non-specific - Metabolism" "Cluster 55: Non-specific - Transcription" "Cluster 40: Non-specific - Unknown function" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 24 Nucleoplasm "HPA055357: " "unprognostic (1.12e-2)" "unprognostic (1.31e-2)" "unprognostic (1.64e-1)" "unprognostic (2.01e-2)" "unprognostic (1.27e-1)" "potential prognostic unfavorable (3.64e-4)" "unprognostic (1.39e-1)" "unprognostic (2.06e-1)" "unprognostic (5.83e-2)" "unprognostic (3.29e-3)" "potential prognostic favorable (1.22e-5)" "unprognostic (3.51e-3)" "unprognostic (2.27e-1)" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (2.96e-2)" "unprognostic (2.19e-2)" "unprognostic (1.07e-1)" "unprognostic (3.09e-1)" "unprognostic (6.11e-2)" "unprognostic (2.91e-2)" "unprognostic (1.58e-1)" "unprognostic (4.40e-3)" "unprognostic (3.09e-2)" "unprognostic (2.52e-1)" "unprognostic (2.96e-2)" "unprognostic (1.20e-1)" "unprognostic (3.07e-1)" "unprognostic (1.90e-1)" "unprognostic (2.87e-2)" "unprognostic (2.58e-2)" ZIC1 "ZIC, ZNF201" ENSG00000152977 "Zic family member 1" Q15915 3 147393422-147510293 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Craniosynostosis, Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "brain: 536.2" "Cell type enhanced" "Detected in some" "Astrocytes: 95.0;Bergmann glia: 619.8;Brain excitatory neurons: 143.8;Choroid plexus epithelial cells: 104.9;Ependymal cells: 285.8;Myonuclei: 73.4;Myosatellite cells: 80.3;Oligodendrocytes: 57.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 285.8;Glial cells: 619.8;Neuronal cells: 143.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 665.5;fibroblast: 888.0;pericyte: 644.8" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 56.6" "Region enriched" "Detected in all" 5 "cerebellum: 1312.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "Rhabdoid: 28.8" "Region enhanced" "Detected in all" "cerebellum: 207.5" "Region enriched" "Detected in all" 8 "cerebellum: 608.2" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 139 "salivary gland: 13919.3" HPA004098 Supported Supported Nucleoplasm NA NA "Cluster 71: Cerebellum - Nervous system development" "Cluster 35: Non-specific - DNA binding" "Cluster 5: Rhabdoid - Unknown function" "Cluster 22: Non-specific - Basic cellular functions" 59 Nucleoplasm "HPA004098: " "unprognostic (2.90e-2)" "unprognostic (3.67e-1)" "unprognostic (1.16e-1)" "unprognostic (2.12e-2)" "unprognostic (1.69e-2)" "unprognostic (3.02e-1)" "unprognostic (2.05e-1)" "unprognostic (6.22e-2)" "unprognostic (1.08e-1)" "unprognostic (1.06e-1)" "unprognostic (8.93e-2)" "unprognostic (2.80e-1)" "unprognostic (9.44e-2)" "unprognostic (1.98e-1)" "unprognostic (6.19e-2)" "unprognostic (9.92e-2)" "unprognostic (8.96e-2)" ZIC3 "HTX, HTX1, ZNF203" ENSG00000156925 "Zic family member 3" O60481 X 137566127-137577691 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Heterotaxy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 17.7" "Cell type enhanced" "Detected in some" "Bergmann glia: 23.8;Brain excitatory neurons: 3.4;Choroid plexus epithelial cells: 2.9;Ependymal cells: 1.8;Müller glia: 5.0;Other brain neurons: 6.6;Undifferentiated spermatogonia: 2.7" "Group enriched" "Detected in some" 5 "Glial cells: 23.8;Neuronal cells: 6.6" "Cell type enhanced" "Detected in some" "Bergmann glia: 33.5;endothelial cell: 28.2;fibroblast: 14.8" "Cancer enriched" "Detected in single" 11 "Testicular Germ Cell Tumor (TCGA): 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 9 "testis cancer: 22.8" "Pituitary gland - Fibroblasts, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052936, HPA069523" Uncertain Supported Nucleoplasm NA NA "Cluster 27: Cerebellum - Synaptic function" "Cluster 15: Non-specific - Transcription" "Cluster 34: Testis cancer - Unknown function" "Cluster 104: Brain endothelial cells - Blood brain barrier" 1 Nucleoplasm "HPA052936: , HPA069523: " "unprognostic (1.16e-2)" "unprognostic (3.37e-1)" ZKSCAN1 "KOX18, PHZ-37, ZNF139, ZNF36, ZSCAN33" ENSG00000106261 "Zinc finger with KRAB and SCAN domains 1" P17029 7 100015572-100041689 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 381.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in some" "fallopian tube: 363878.7" HPA006672 Uncertain Approved "Nucleoplasm,Nuclear bodies,Mitochondria" Yes No "Cluster 30: Non-specific - DNA binding" "Cluster 70: Non-specific - Protein processing" "Cluster 6: Non-specific - Immune response" "Cluster 71: Lymphoma - Inflammatory response" "Cluster 16: Prostatic glandular cells - Androgen response & seminal fluid" 14 "Nucleoplasm, Nuclear bodies" Mitochondria "HPA006672: " "unprognostic (1.27e-2)" "unprognostic (2.73e-2)" "unprognostic (3.15e-1)" "unprognostic (1.32e-2)" "unprognostic (2.95e-1)" "unprognostic (8.93e-3)" "unprognostic (3.75e-1)" "unprognostic (1.12e-1)" "unprognostic (2.11e-2)" "unprognostic (6.31e-3)" "potential prognostic favorable (5.79e-4)" "unprognostic (8.01e-3)" "unprognostic (4.17e-2)" "unprognostic (2.56e-2)" "unprognostic (8.18e-3)" "unprognostic (1.23e-1)" "unprognostic (2.65e-2)" "unprognostic (1.45e-2)" "unprognostic (3.29e-2)" "unprognostic (3.87e-3)" "unprognostic (2.80e-1)" "unprognostic (5.05e-2)" "unprognostic (2.96e-1)" "unprognostic (1.12e-1)" "unprognostic (9.75e-2)" "unprognostic (3.97e-1)" "unprognostic (1.60e-2)" "unprognostic (2.77e-1)" "unprognostic (4.66e-1)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" ZKSCAN3 "ZF47, Zfp47, ZNF306, ZNF309, ZSCAN35" ENSG00000189298 "Zinc finger with KRAB and SCAN domains 3" Q9BRR0 6 28349947-28369172 "Predicted intracellular proteins, Transcription factors" "Autophagy, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Epicardial cells: 36.4;Tuft cells: 34.6" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 36.4;Secretory gland support: 34.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009637, HPA060116" Approved Supported Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 61: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 47: Leukemia - Hemostasis" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 14 Nucleoplasm "HPA009637: , HPA060116: " "unprognostic (1.18e-2)" "unprognostic (6.41e-2)" "unprognostic (3.55e-1)" "unprognostic (6.85e-2)" "unprognostic (1.45e-1)" "unprognostic (3.00e-1)" "unprognostic (1.43e-2)" "unprognostic (3.40e-2)" "unprognostic (5.14e-2)" "unprognostic (7.08e-3)" "unprognostic (5.63e-3)" "unprognostic (8.50e-3)" "unprognostic (6.53e-2)" "unprognostic (1.01e-3)" "unprognostic (2.23e-1)" "unprognostic (2.88e-2)" "unprognostic (3.59e-2)" "unprognostic (2.37e-1)" "unprognostic (1.08e-1)" "unprognostic (5.96e-2)" "unprognostic (1.92e-3)" "unprognostic (3.49e-2)" "unprognostic (1.73e-1)" "unprognostic (2.16e-1)" "unprognostic (2.84e-3)" "unprognostic (2.70e-1)" "unprognostic (3.13e-2)" "unprognostic (1.96e-1)" "unprognostic (1.29e-1)" "unprognostic (2.58e-2)" "unprognostic (2.04e-1)" ZKSCAN4 "FLJ32136, P1P373C6, p373c6.1, ZNF307, ZNF427, ZSCAN36" ENSG00000187626 "Zinc finger with KRAB and SCAN domains 4" Q969J2 6 28241697-28252269 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.5;Kupffer cells: 33.8;Late primary spermatocytes: 61.0" "Cell type enhanced" "Detected in many" "Mononuclear phagocytes: 33.8;Spermatogenic cell types: 61.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 213521.0;Granulosa cells: 386270.2;Oocytes: 588267.0;T-cells: 730582.3" "Not detected" "Not detected" HPA009637 Approved Supported Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 39: Testis - Nuclear processes" "Cluster 2: Neurons - Nucleosome" "Cluster 28: Non-specific - Nuclear processes" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 35 Nucleoplasm "HPA009637: " "unprognostic (1.51e-1)" "unprognostic (1.64e-1)" "unprognostic (1.68e-1)" "unprognostic (3.07e-2)" "unprognostic (2.25e-1)" "unprognostic (3.86e-1)" "unprognostic (4.69e-2)" "potential prognostic favorable (9.46e-4)" "unprognostic (1.06e-2)" "potential prognostic favorable (6.35e-4)" "unprognostic (7.81e-2)" "unprognostic (1.97e-1)" "potential prognostic unfavorable (2.62e-7)" "unprognostic (1.55e-1)" "unprognostic (3.52e-2)" "unprognostic (3.09e-1)" "unprognostic (1.27e-1)" "unprognostic (2.85e-3)" "unprognostic (2.76e-2)" "unprognostic (5.07e-2)" "unprognostic (5.50e-2)" "unprognostic (1.91e-1)" "unprognostic (4.50e-2)" "unprognostic (1.07e-3)" "unprognostic (9.49e-3)" "unprognostic (2.04e-3)" "unprognostic (1.33e-1)" "unprognostic (1.74e-1)" "unprognostic (1.30e-1)" "unprognostic (7.52e-2)" ZKSCAN5 "ZFP95, ZNF914, ZSCAN37" ENSG00000196652 "Zinc finger with KRAB and SCAN domains 5" Q9Y2L8 7 99504662-99534700 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA003201 Uncertain Approved "Intermediate filaments" No No "Cluster 33: Non-specific - ATP binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 16: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 7 "Intermediate filaments" "HPA003201: " "unprognostic (2.26e-1)" "unprognostic (6.76e-2)" "unprognostic (5.33e-2)" "unprognostic (8.01e-3)" "unprognostic (5.32e-2)" "unprognostic (1.70e-1)" "unprognostic (8.98e-2)" "unprognostic (3.37e-2)" "unprognostic (2.22e-2)" "potential prognostic unfavorable (1.89e-4)" "unprognostic (2.42e-3)" "unprognostic (8.42e-2)" "unprognostic (2.49e-2)" "potential prognostic unfavorable (5.47e-6)" "unprognostic (1.14e-2)" "unprognostic (1.56e-1)" "unprognostic (2.03e-2)" "unprognostic (4.57e-2)" "unprognostic (8.83e-3)" "unprognostic (2.39e-1)" "unprognostic (2.93e-1)" "unprognostic (6.79e-2)" "potential prognostic unfavorable (7.20e-4)" "unprognostic (1.86e-1)" "unprognostic (2.98e-2)" "unprognostic (7.37e-2)" "unprognostic (1.95e-1)" "unprognostic (2.69e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-3)" "unprognostic (1.45e-1)" ZKSCAN7 "FLJ12738, ZNF167, ZNF448, ZNF64, ZSCAN39" ENSG00000196345 "Zinc finger with KRAB and SCAN domains 7" Q9P0L1 3 44555193-44594173 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 8.5;Bergmann glia: 11.6;Brain excitatory neurons: 6.9;Brain inhibitory neurons: 6.7;Choroid plexus epithelial cells: 9.9;Distal convoluted tubule cells: 9.6;Ependymal cells: 6.9;Late primary spermatocytes: 9.5;Late spermatids: 22.4;Loop of henle epithelial cells: 10.0;Microglia: 5.9;Oligodendrocyte progenitor cells: 12.0;Oligodendrocytes: 9.7;Other brain neurons: 6.6;Podocytes: 6.2;Proximal tubule cells: 7.6;Renal collecting duct intercalated cells: 7.1;Renal collecting duct principal cells: 6.9;Renal connecting tubule cells: 8.0" "Cell type enhanced" "Detected in some" "Ciliated cells: 9.9;Ductal cells: 8.0;Glial cells: 12.0;Neuronal cells: 6.9;Renal nephron cells: 10.0;Spermatogenic cell types: 22.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 2.9;testis cancer: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048312, HPA049906, HPA071850" Uncertain Supported "Nuclear speckles,Cytosol" NA NA "Cluster 21: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 102: Non-specific - Mixed function" 5 Cytosol "Nuclear speckles" "HPA048312: , HPA049906: , HPA071850: " "unprognostic (3.84e-2)" "unprognostic (7.14e-2)" "unprognostic (2.23e-1)" "unprognostic (1.93e-1)" "potential prognostic favorable (7.78e-4)" "unprognostic (3.55e-1)" "unprognostic (1.30e-1)" "unprognostic (1.05e-1)" "unprognostic (1.27e-1)" "unprognostic (4.92e-2)" "unprognostic (9.75e-2)" "unprognostic (3.50e-3)" "unprognostic (5.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.24e-2)" "unprognostic (3.39e-1)" ZMAT4 FLJ13842 ENSG00000165061 "Zinc finger matrin-type 4" Q9H898 8 40530590-40897833 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 12.9;retina: 4.1;thyroid gland: 15.3" "Cell type enhanced" "Detected in many" "Brain excitatory neurons: 151.0;Brain inhibitory neurons: 394.5;Late spermatids: 88.1;Medullary thymic epithelial cells: 158.4;Other brain neurons: 221.7;Retinal amacrine cells: 525.5;Retinal ganglion cells: 448.1;Somatotrophs: 131.8;Thyrotrophs: 165.4;Tuft cells: 230.6" "Cell type enhanced" "Detected in many" "Neuronal cells: 525.5;Pituitary endocrine cells: 165.4;Secretory gland support: 230.6" "Cell type enhanced" "Detected in many" "midbrain-derived inhibitory: 1206.1" "Cancer enhanced" "Detected in some" "Kidney Renal Clear Cell Carcinoma (TCGA): 3.2;Thyroid Carcinoma (TCGA): 4.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 86 "NK-cell: 8.6" "Lineage enriched" "Detected in single" 86 "NK-cells: 8.6" "Cancer enhanced" "Detected in some" "Neuroblastoma: 6.9" "Adrenal gland - Adrenal medulla cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 3085 "Neurons: 308454.3" "Not detected" "Not detected" "HPA069813, HPA071585" Enhanced Approved Nucleoplasm,Nucleoli No NA "Cluster 15: NK-cells - Unknown function" "Cluster 78: Brain - Neuronal signaling" "Cluster 52: Neurons & Synapses - Synaptic function" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 109: Neurons - Neuronal signaling" 2 "Nucleoplasm, Nucleoli" "HPA069813: , HPA071585: " "unprognostic (2.14e-2)" "unprognostic (2.22e-1)" "unprognostic (2.14e-1)" "unprognostic (9.45e-2)" "unprognostic (8.84e-2)" "unprognostic (5.19e-1)" "potential prognostic unfavorable (1.37e-4)" ZMIZ2 "DKFZp761I2123, hZIMP7, KIAA1886, NET27, ZIMP7" ENSG00000122515 "Zinc finger MIZ-type containing 2" Q8NF64 7 44748581-44769881 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 156.0" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 156.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 1784881.7" "Tissue enriched" "Detected in single" 32437 "lymphoid tissue: 3243745.4" "HPA040716, HPA071991" Supported Supported Nucleoplasm,Mitochondria No No "Cluster 32: Basophils - Transcription" "Cluster 68: Non-specific - Basic cellular processes" "Cluster 51: Neurons - Mixed function" "Cluster 67: Non-specific - Unknown function" "Cluster 82: Dendritic cells - Antigen presentation" 5 Nucleoplasm Mitochondria "HPA040716: , HPA071991: " "unprognostic (2.41e-3)" "unprognostic (1.63e-1)" "unprognostic (1.29e-1)" "unprognostic (5.76e-2)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (3.54e-1)" "unprognostic (3.40e-1)" "unprognostic (1.85e-3)" "unprognostic (2.85e-2)" "potential prognostic favorable (9.23e-4)" "unprognostic (4.88e-2)" "unprognostic (1.62e-2)" "potential prognostic unfavorable (8.01e-4)" "unprognostic (1.25e-1)" "unprognostic (1.31e-2)" "unprognostic (5.65e-2)" "unprognostic (3.48e-2)" "unprognostic (1.42e-1)" "unprognostic (1.68e-1)" "unprognostic (1.01e-2)" "unprognostic (1.02e-1)" "potential prognostic unfavorable (8.05e-4)" "unprognostic (1.68e-1)" "unprognostic (2.41e-2)" "unprognostic (3.60e-3)" "unprognostic (2.87e-1)" "unprognostic (4.50e-1)" "unprognostic (1.69e-1)" "unprognostic (8.63e-2)" "unprognostic (1.40e-1)" ZMYM4 "KIAA0425, MYM, ZNF198L3, ZNF262" ENSG00000146463 "Zinc finger MYM-type containing 4" Q5VZL5 1 35268709-35422058 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adipose visceral - Adipose progenitor cells, Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cell types: 1965327.9;Granulosa cells: 2070906.3" "Tissue enriched" "Detected in some" "lymphoid tissue: 5801470.5" "HPA051301, HPA054802" Approved Approved Nucleoplasm,Nucleoli,Cytosol No No "Cluster 8: Plasmacytoid DCs - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 38 Nucleoplasm "Nucleoli, Cytosol" "HPA051301: , HPA054802: " "unprognostic (3.57e-3)" "unprognostic (2.78e-1)" "unprognostic (1.56e-1)" "unprognostic (1.79e-2)" "unprognostic (6.05e-2)" "unprognostic (6.29e-2)" "unprognostic (2.17e-1)" "unprognostic (1.76e-2)" "unprognostic (8.36e-2)" "unprognostic (1.38e-2)" "potential prognostic favorable (6.55e-4)" "unprognostic (1.04e-1)" "unprognostic (2.27e-1)" "potential prognostic unfavorable (8.10e-7)" "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (3.44e-1)" "unprognostic (9.15e-2)" "unprognostic (1.83e-1)" "unprognostic (4.84e-2)" "unprognostic (4.59e-1)" "unprognostic (3.44e-2)" "unprognostic (2.11e-1)" "unprognostic (5.27e-2)" "unprognostic (3.52e-2)" "unprognostic (3.31e-1)" "unprognostic (1.84e-2)" "unprognostic (1.25e-1)" "unprognostic (9.98e-2)" "unprognostic (6.22e-2)" "unprognostic (1.41e-1)" ZMYND10 "BLU, CILD22, DNAAF7" ENSG00000004838 "Zinc finger MYND-type containing 10" O75800 3 50341110-50345732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "choroid plexus: 80.2;fallopian tube: 113.1;testis: 226.5" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 129.3;Early spermatids: 234.5;Endometrial ciliated cells: 258.6;Ependymal cells: 149.8;Epididymal efferent duct ciliated cells: 465.0;Fallopian tube ciliated cells: 606.8;Late primary spermatocytes: 1156.1;Late spermatids: 649.7;Respiratory ciliated cells: 611.3" "Group enriched" "Detected in many" 85 "Ciliated cells: 611.3;Spermatogenic cell types: 1156.1" "Cell type enriched" "Detected in many" 5 "ependymal cell: 205.6" "Cancer enhanced" "Detected in many" "Uterine Corpus Endometrial Carcinoma (TCGA): 24.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.2" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 78593 "Fallopian tube cells: 7859313.9" "Tissue enriched" "Detected in single" 99729 "fallopian tube: 9972921.7" HPA035255 Approved "Plasma membrane,Basal body,Cytosol" NA NA "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 3: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 107: Ciliated cells - Cilia assembly & function" 12 "Plasma membrane, Basal body" Cytosol "HPA035255: " "unprognostic (4.53e-2)" "unprognostic (8.92e-3)" "unprognostic (2.87e-1)" "potential prognostic favorable (9.41e-4)" "unprognostic (2.26e-1)" "unprognostic (3.65e-3)" "unprognostic (7.99e-2)" "unprognostic (2.98e-1)" "potential prognostic favorable (1.17e-5)" "unprognostic (2.54e-1)" "unprognostic (4.08e-2)" "unprognostic (1.77e-1)" "unprognostic (2.21e-1)" "unprognostic (1.53e-1)" "unprognostic (3.48e-1)" "unprognostic (1.27e-2)" "unprognostic (2.91e-2)" "unprognostic (9.51e-3)" "unprognostic (7.70e-2)" "unprognostic (2.19e-1)" "unprognostic (3.63e-2)" "unprognostic (1.47e-1)" ZNF131 "pHZ-10, ZBTB35" ENSG00000172262 "Zinc finger protein 131" P52739 5 43065176-43192021 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 537781.5;Neurons: 238664.8;Neutrophils: 224661.0;T-cells: 558353.1" "Group enriched" "Detected in some" 3057 "bone marrow: 359486.4;intestine: 406412.8;lymphoid tissue: 299994.3;ovary: 157005.2" "HPA007023, HPA027748, HPA074630" Approved Enhanced "Nucleoplasm,Intermediate filaments" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 16: Non-specific - Transcription" "Cluster 29: Non-specific - Unknown function" "Cluster 103: Non-specific - Basic cellular processes" 11 Nucleoplasm "Intermediate filaments" "HPA007023: , HPA027748: , HPA074630: " "unprognostic (1.76e-1)" "unprognostic (6.84e-3)" "unprognostic (1.31e-1)" "unprognostic (1.91e-1)" "unprognostic (1.42e-2)" "unprognostic (1.59e-3)" "unprognostic (1.42e-1)" "unprognostic (9.31e-3)" "unprognostic (7.42e-2)" "potential prognostic unfavorable (1.35e-4)" "unprognostic (3.04e-1)" "unprognostic (2.22e-1)" "unprognostic (1.10e-1)" "potential prognostic unfavorable (6.96e-6)" "unprognostic (2.63e-1)" "unprognostic (7.94e-2)" "unprognostic (1.13e-2)" "unprognostic (4.90e-2)" "unprognostic (8.55e-2)" "unprognostic (6.20e-2)" "unprognostic (3.87e-1)" "unprognostic (4.36e-2)" "potential prognostic unfavorable (3.18e-4)" "unprognostic (2.59e-2)" "unprognostic (4.02e-2)" "potential prognostic unfavorable (2.99e-4)" "unprognostic (1.86e-2)" "unprognostic (3.93e-2)" "unprognostic (1.53e-1)" "unprognostic (2.25e-3)" "unprognostic (1.52e-1)" ZNF143 "pHZ-1, SBF, STAF" ENSG00000166478 "Zinc finger protein 143" P52747 11 9460319-9528524 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 183.3" "Cell type enhanced" "Detected in all" "Neutrophils: 183.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Neutrophils: 1054293.7;T-cells: 466986.2" "Tissue enriched" "Detected in single" 2362 "lymphoid tissue: 236166.4" "HPA003263, HPA003264, HPA074818" Supported Supported "Nucleoplasm,Nuclear bodies,Golgi apparatus,Vesicles" NA NA "Cluster 42: Non-specific - Vesicular transport" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 24: Non-specific - Unknown function" "Cluster 65: Non-specific - Cell growth & division" 21 Nucleoplasm "Nuclear bodies, Golgi apparatus, Vesicles" "HPA003263: , HPA003264: , HPA074818: " "unprognostic (2.02e-1)" "unprognostic (7.93e-2)" "unprognostic (3.42e-2)" "potential prognostic unfavorable (1.26e-5)" "unprognostic (4.10e-2)" "unprognostic (6.53e-2)" "unprognostic (1.85e-1)" "unprognostic (2.70e-2)" "unprognostic (1.20e-1)" "potential prognostic unfavorable (4.58e-5)" "validated prognostic favorable (1.41e-4)" "validated prognostic favorable (2.57e-4)" "unprognostic (1.33e-1)" "unprognostic (7.26e-3)" "unprognostic (1.42e-1)" "unprognostic (7.56e-2)" "potential prognostic unfavorable (3.06e-4)" "unprognostic (3.39e-2)" "unprognostic (1.49e-1)" "unprognostic (3.16e-1)" "unprognostic (1.16e-2)" "unprognostic (8.35e-3)" "unprognostic (3.00e-3)" "unprognostic (1.14e-2)" "unprognostic (1.61e-2)" "unprognostic (2.09e-1)" "unprognostic (8.07e-2)" "unprognostic (9.30e-3)" "unprognostic (5.96e-2)" "unprognostic (8.54e-2)" "unprognostic (1.40e-1)" ZNF200 ENSG00000010539 "Zinc finger protein 200" P98182 16 3222325-3236221 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 16.8" "Cell type enhanced" "Detected in many" "Differentiating spermatogonia: 38.8;Early primary spermatocytes: 48.3;Early spermatids: 43.1;Late primary spermatocytes: 55.1;Neutrophils: 48.2;Tuft cells: 34.6;Undifferentiated spermatogonia: 29.8" "Cell type enhanced" "Detected in many" "Neutrophils: 48.2;Secretory gland support: 34.6;Spermatogenic cell types: 55.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018981, HPA059310" Uncertain Approved Mitochondria No No "Cluster 4: Neutrophils - Degranulation" "Cluster 39: Testis - Nuclear processes" "Cluster 35: Non-specific - DNA binding" "Cluster 54: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 Mitochondria "HPA018981: , HPA059310: " "unprognostic (8.46e-2)" "unprognostic (5.26e-2)" "unprognostic (8.62e-2)" "unprognostic (2.45e-1)" "unprognostic (4.84e-2)" "unprognostic (2.16e-3)" "unprognostic (1.62e-1)" "unprognostic (1.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.11e-1)" "potential prognostic favorable (9.01e-6)" "unprognostic (2.03e-1)" "unprognostic (4.45e-2)" "unprognostic (3.24e-2)" "unprognostic (1.29e-1)" "unprognostic (1.27e-2)" "unprognostic (3.36e-1)" "unprognostic (2.02e-1)" "unprognostic (8.97e-3)" "unprognostic (3.03e-1)" "unprognostic (4.34e-1)" "unprognostic (1.73e-1)" "unprognostic (1.81e-3)" "unprognostic (1.81e-2)" "potential prognostic favorable (7.99e-4)" "unprognostic (2.20e-1)" "unprognostic (4.62e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (1.48e-1)" "unprognostic (4.38e-1)" ZNF202 "ZKSCAN10, ZSCAN42" ENSG00000166261 "Zinc finger protein 202" O95125 11 123723914-123741675 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2055 "Granulosa cells: 205536.3" "Not detected" "Not detected" HPA059229 Approved "Nucleoli rim,Nuclear bodies,Mitotic chromosome" Yes No "Cluster 24: Non-specific - Transcription" "Cluster 39: Testis - Nuclear processes" "Cluster 34: Non-specific - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 17: Non-specific - RNA processing" 17 "Nucleoli rim, Mitotic chromosome" "Nuclear bodies" "HPA059229: " "unprognostic (3.74e-2)" "unprognostic (1.13e-2)" "potential prognostic favorable (5.00e-4)" "unprognostic (1.07e-1)" "unprognostic (7.21e-2)" "unprognostic (3.05e-1)" "unprognostic (6.53e-2)" "potential prognostic favorable (6.09e-4)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.12e-1)" "potential prognostic favorable (7.60e-4)" "unprognostic (7.16e-2)" "potential prognostic unfavorable (4.05e-6)" "unprognostic (9.25e-2)" "unprognostic (1.86e-2)" "unprognostic (1.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.41e-3)" "unprognostic (1.29e-1)" "unprognostic (1.09e-1)" "unprognostic (9.06e-2)" "potential prognostic unfavorable (2.75e-4)" "unprognostic (2.88e-2)" "potential prognostic favorable (4.38e-4)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (9.32e-4)" "unprognostic (9.03e-2)" "unprognostic (1.40e-1)" "unprognostic (2.53e-1)" "unprognostic (2.29e-2)" ZNF214 ENSG00000149050 "Zinc finger protein 214" Q9UL59 11 6997085-7020346 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ependymal cells: 47.3;Epididymal efferent duct ciliated cells: 22.2;Fallopian tube ciliated cells: 34.0;Late primary spermatocytes: 27.6;Respiratory ciliated cells: 53.9" "Cell type enhanced" "Detected in many" "Ciliated cells: 53.9;Spermatogenic cell types: 27.6" "Cell type enhanced" "Detected in many" "ependymal cell: 54.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Lung - Respiratory ciliated cells, Testis - Early spermatids" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 3607 "liver: 360703.9" HPA055391 Uncertain Approved Nucleoplasm,Midbody Yes NA "Cluster 65: Brain - Transcription" "Cluster 17: Choroid plexus - Cilium" "Cluster 10: Ciliated cells - Ion channel activity" "Cluster 34: Ciliated cells - Cilia assembly & function" Nucleoplasm Midbody "HPA055391: " "unprognostic (3.18e-1)" "unprognostic (1.88e-1)" "unprognostic (2.78e-3)" "unprognostic (6.18e-2)" "unprognostic (7.80e-2)" "unprognostic (6.77e-3)" "potential prognostic favorable (9.59e-6)" "unprognostic (3.83e-3)" "unprognostic (1.68e-2)" "unprognostic (3.64e-2)" "unprognostic (4.37e-2)" "unprognostic (1.02e-1)" "unprognostic (2.46e-1)" "unprognostic (7.96e-2)" "unprognostic (6.72e-2)" "unprognostic (1.34e-1)" "unprognostic (3.26e-2)" "unprognostic (2.64e-2)" "unprognostic (2.03e-1)" "unprognostic (1.91e-2)" ZNF22 "HKR-T1, KOX15, Zfp422, ZNF422" ENSG00000165512 "Zinc finger protein 22" P17026 10 45000923-45005326 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Skin - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "B-cells: 1972302.4;Capillaries: 928952.8;Neutrophils: 855776.9;T-cells: 2869746.8" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9381441.4" "HPA016736, HPA054893" Approved Enhanced Nucleoplasm NA NA "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 51: Lymphoid tissue - Adaptive immune response" "Cluster 55: Non-specific - Transcription" "Cluster 6: Leukemia - Signal transduction" "Cluster 17: Non-specific - RNA processing" 22 Nucleoplasm "HPA016736: , HPA054893: " "unprognostic (1.64e-1)" "unprognostic (1.46e-1)" "unprognostic (4.17e-1)" "potential prognostic unfavorable (8.30e-4)" "unprognostic (1.30e-1)" "unprognostic (3.68e-2)" "unprognostic (3.91e-3)" "potential prognostic favorable (2.01e-5)" "unprognostic (1.05e-1)" "unprognostic (9.35e-2)" "unprognostic (3.14e-3)" "unprognostic (4.45e-2)" "unprognostic (2.32e-1)" "unprognostic (2.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.35e-1)" "unprognostic (1.60e-1)" "unprognostic (8.66e-2)" "unprognostic (3.90e-2)" "unprognostic (2.20e-1)" "unprognostic (2.26e-1)" "unprognostic (7.85e-2)" "unprognostic (1.03e-1)" "unprognostic (5.20e-2)" "unprognostic (6.68e-2)" "unprognostic (8.58e-2)" "unprognostic (2.62e-3)" "potential prognostic unfavorable (1.63e-4)" "unprognostic (1.84e-1)" "unprognostic (4.84e-2)" "unprognostic (2.63e-1)" ZNF226 ENSG00000167380 "Zinc finger protein 226" Q9NYT6 19 44165073-44178381 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA006145, CAB034353, HPA069192" Uncertain Approved "Nuclear bodies" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 "Nuclear bodies" "CAB034353: , HPA006145: , HPA069192: " "potential prognostic favorable (5.57e-4)" "unprognostic (1.88e-1)" "unprognostic (2.15e-2)" "unprognostic (1.02e-1)" "unprognostic (1.17e-1)" "unprognostic (7.21e-2)" "unprognostic (2.33e-1)" "unprognostic (3.99e-1)" "unprognostic (8.58e-2)" "unprognostic (1.62e-2)" "unprognostic (3.53e-3)" "unprognostic (2.80e-2)" "potential prognostic favorable (1.86e-4)" "unprognostic (1.62e-1)" "unprognostic (1.60e-2)" "unprognostic (3.15e-3)" "unprognostic (1.27e-1)" "unprognostic (7.09e-2)" "unprognostic (2.17e-2)" "unprognostic (3.07e-1)" "unprognostic (2.27e-1)" "unprognostic (1.05e-2)" "unprognostic (8.40e-2)" "unprognostic (1.80e-1)" "unprognostic (2.90e-1)" "unprognostic (5.60e-2)" "unprognostic (1.41e-3)" "unprognostic (7.74e-2)" "unprognostic (7.03e-3)" "unprognostic (1.89e-1)" "unprognostic (1.47e-1)" ZNF230 FDZF2 ENSG00000159882 "Zinc finger protein 230" Q9UIE0 19 44002957-44013924 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 18.6;Neutrophils: 54.4" "Cell type enhanced" "Detected in many" "Neutrophils: 54.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA006172 Approved Mitochondria No No "Cluster 36: Eosinophils - Protein ubiquitination" "Cluster 61: Non-specific - Transcription" "Cluster 16: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 24: Neutrophils - Innate immunity signal integration" 6 Mitochondria "HPA006172: " "unprognostic (4.75e-2)" "unprognostic (2.44e-2)" "unprognostic (9.30e-3)" "unprognostic (2.00e-3)" "unprognostic (2.30e-1)" "unprognostic (1.24e-1)" "unprognostic (1.83e-1)" "unprognostic (5.03e-3)" "unprognostic (2.82e-2)" "unprognostic (9.85e-2)" "potential prognostic favorable (5.98e-4)" "unprognostic (6.71e-3)" "unprognostic (4.00e-2)" "unprognostic (9.39e-2)" "unprognostic (2.13e-1)" "unprognostic (6.32e-2)" "unprognostic (3.25e-2)" "unprognostic (1.47e-1)" "unprognostic (3.17e-1)" "unprognostic (4.24e-2)" "unprognostic (5.87e-3)" "unprognostic (1.56e-1)" "unprognostic (4.21e-2)" "unprognostic (2.69e-2)" "unprognostic (2.51e-2)" "unprognostic (2.71e-2)" "unprognostic (2.54e-1)" "unprognostic (3.25e-1)" "unprognostic (9.29e-2)" "potential prognostic unfavorable (4.02e-4)" ZNF25 "FLJ31890, KOX19, Zfp9" ENSG00000175395 "Zinc finger protein 25" P17030 10 37949573-37976647 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Lactotrophs: 68.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Fibroblasts" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 54439 "Neurons: 5443922.9" "Not detected" "Not detected" HPA030190 Uncertain Approved "Nucleoplasm,Golgi apparatus" No No "Cluster 42: Non-specific - Vesicular transport" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 1: Neurons - Mixed function" "Cluster 64: Connective tissue cells - ECM organization" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Nucleoplasm, Golgi apparatus" "HPA030190: " "unprognostic (9.54e-3)" "unprognostic (8.30e-2)" "unprognostic (4.15e-2)" "unprognostic (3.50e-2)" "unprognostic (1.61e-2)" "unprognostic (3.29e-1)" "unprognostic (1.46e-1)" "potential prognostic favorable (5.28e-4)" "unprognostic (1.63e-2)" "unprognostic (1.36e-1)" "potential prognostic favorable (9.90e-5)" "unprognostic (1.68e-2)" "unprognostic (3.37e-1)" "unprognostic (3.54e-2)" "unprognostic (2.42e-1)" "unprognostic (1.03e-3)" "unprognostic (1.32e-1)" "unprognostic (1.72e-1)" "unprognostic (3.50e-2)" "unprognostic (1.65e-1)" "unprognostic (1.26e-2)" "unprognostic (1.31e-3)" "unprognostic (2.79e-1)" "unprognostic (2.20e-1)" "unprognostic (4.15e-2)" "unprognostic (2.09e-1)" "unprognostic (5.27e-2)" "unprognostic (3.45e-2)" "unprognostic (1.24e-1)" "potential prognostic unfavorable (4.84e-4)" "unprognostic (1.50e-1)" ZNF250 "MGC9718, ZFP647, ZNF647" ENSG00000196150 "Zinc finger protein 250" P15622 8 144876497-144902168 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 95.1" "Cell type enhanced" "Detected in many" "Neutrophils: 95.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 960 "Granulosa cells: 96001.4" "Not detected" "Not detected" HPA020853 Uncertain Approved "Nuclear speckles,Cytosol" NA NA "Cluster 16: Non-specific - Cell proliferation" "Cluster 64: Non-specific - Transcription" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 40: Non-specific - Unknown function" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 5 "Nuclear speckles" Cytosol "HPA020853: " "unprognostic (9.23e-3)" "unprognostic (1.54e-2)" "unprognostic (2.84e-1)" "unprognostic (1.08e-1)" "unprognostic (5.45e-2)" "potential prognostic unfavorable (6.38e-4)" "unprognostic (4.47e-2)" "potential prognostic favorable (1.60e-5)" "unprognostic (1.07e-2)" "unprognostic (1.67e-1)" "validated prognostic favorable (1.67e-4)" "validated prognostic favorable (7.37e-4)" "unprognostic (4.30e-2)" "unprognostic (3.02e-3)" "unprognostic (9.35e-2)" "unprognostic (1.64e-1)" "unprognostic (3.55e-2)" "unprognostic (1.18e-1)" "unprognostic (6.14e-2)" "unprognostic (2.44e-1)" "unprognostic (1.74e-1)" "unprognostic (1.57e-1)" "unprognostic (1.66e-2)" "unprognostic (8.46e-2)" "unprognostic (7.84e-2)" "unprognostic (3.90e-1)" "unprognostic (3.13e-1)" "unprognostic (2.07e-1)" "unprognostic (1.12e-1)" "unprognostic (9.28e-3)" "unprognostic (1.81e-1)" ZNF263 "FPM315, ZKSCAN12, ZSCAN44" ENSG00000006194 "Zinc finger protein 263" O14978 16 3283283-3301401 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 51.8;Late primary spermatocytes: 64.1;Late spermatids: 44.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 64.1" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA035085, HPA035086" Approved Supported "Nucleoplasm,Mitotic spindle,Cytosol" Yes No "Cluster 45: Eosinophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 54: Non-specific - Transcription" "Cluster 103: Non-specific - Basic cellular processes" 26 Cytosol "Nucleoplasm, Mitotic spindle" "HPA035085: , HPA035086: " "unprognostic (9.67e-3)" "unprognostic (2.61e-2)" "unprognostic (1.82e-1)" "unprognostic (1.47e-1)" "unprognostic (3.67e-2)" "unprognostic (5.10e-2)" "unprognostic (2.97e-1)" "unprognostic (1.43e-3)" "unprognostic (1.21e-1)" "unprognostic (2.55e-2)" "potential prognostic favorable (3.30e-5)" "unprognostic (7.07e-3)" "unprognostic (3.99e-1)" "unprognostic (1.77e-2)" "unprognostic (2.81e-2)" "unprognostic (2.37e-1)" "unprognostic (2.76e-1)" "unprognostic (3.50e-1)" "potential prognostic favorable (7.00e-4)" "unprognostic (1.27e-1)" "unprognostic (2.04e-1)" "unprognostic (3.12e-2)" "unprognostic (1.84e-1)" "unprognostic (3.35e-2)" "unprognostic (3.21e-3)" "unprognostic (2.23e-1)" "unprognostic (1.86e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-1)" "unprognostic (6.20e-3)" "unprognostic (6.74e-2)" ZNF286A "KIAA1874, ZNF286" ENSG00000187607 "Zinc finger protein 286A" Q9HBT8 17 15699577-15720787 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Early spermatids: 4.6;Epididymal basal cells: 1.5;Epididymal efferent duct ciliated cells: 2.1;Epididymal principal cells: 1.9;Late spermatids: 6.2;Medullary thymic epithelial cells: 2.4;Respiratory deuterosomal cells: 1.0;Respiratory ionocytes: 2.5" "Cell type enhanced" "Detected in some" "Ciliated cells: 2.1;Ionocytes: 2.5;Secretory gland support: 2.4;Spermatogenic cell types: 6.2" "Cell type enhanced" "Detected in some" "medium spiny neuron: 2.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cancer enhanced" "Detected in all" "testis cancer: 111.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 664 "Granulosa cells: 66439.3" "Not detected" "Not detected" HPA021594 Approved Nucleoli No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 42: Non-specific - Unknown function" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 13 Nucleoli "HPA021594: " "unprognostic (1.00e-1)" "unprognostic (1.44e-1)" "unprognostic (9.22e-2)" "unprognostic (7.22e-2)" "unprognostic (4.12e-1)" "unprognostic (6.67e-2)" "unprognostic (2.27e-1)" "unprognostic (3.06e-3)" "unprognostic (4.80e-2)" "unprognostic (1.13e-3)" "validated prognostic favorable (8.63e-4)" "validated prognostic favorable (5.82e-4)" "unprognostic (9.73e-2)" "unprognostic (5.38e-3)" "unprognostic (1.73e-2)" "unprognostic (1.42e-1)" "unprognostic (1.48e-1)" "unprognostic (2.29e-2)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (1.66e-1)" "unprognostic (3.17e-3)" "unprognostic (9.00e-3)" "unprognostic (2.36e-2)" "unprognostic (1.73e-2)" "unprognostic (1.83e-1)" "unprognostic (1.65e-1)" "unprognostic (4.67e-1)" "unprognostic (1.52e-2)" "unprognostic (3.22e-2)" ZNF287 "ZKSCAN13, ZSCAN45" ENSG00000141040 "Zinc finger protein 287" Q9HBT7 17 16546954-16569204 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Corticotrophs: 21.2" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Pancreatic islets: 192228.8" "Not detected" "Not detected" HPA029290 Uncertain Approved "Golgi apparatus,Basal body" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 69: Parathyroid gland - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 42: Non-specific - Unknown function" "Cluster 59: Pituitary endocrine cells - Neuroendocrine signaling" "Golgi apparatus" "Basal body" "HPA029290: " "unprognostic (1.02e-1)" "unprognostic (1.38e-1)" "unprognostic (7.36e-2)" "unprognostic (3.19e-2)" "unprognostic (9.11e-2)" "unprognostic (4.12e-1)" "unprognostic (1.40e-2)" "unprognostic (1.41e-1)" "unprognostic (1.21e-1)" "potential prognostic favorable (2.52e-5)" "unprognostic (2.29e-1)" "unprognostic (2.73e-1)" "unprognostic (1.78e-3)" "unprognostic (3.55e-1)" "unprognostic (5.95e-2)" "unprognostic (4.75e-2)" "unprognostic (2.18e-1)" "potential prognostic unfavorable (8.75e-6)" "unprognostic (3.53e-3)" "unprognostic (6.82e-2)" "unprognostic (1.49e-2)" "unprognostic (2.46e-2)" "unprognostic (9.32e-2)" "unprognostic (5.77e-3)" "unprognostic (2.00e-1)" "unprognostic (1.20e-1)" "unprognostic (2.80e-1)" ZNF3 "A8-51, FLJ20216, HF.12, KOX25, PP838, Zfp113" ENSG00000166526 "Zinc finger protein 3" P17036 7 100064033-100082548 "Predicted intracellular proteins, Transcription factors" "Differentiation, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 295479.5" "Not detected" "Not detected" HPA003719 Supported Supported Approved Nucleoplasm No No "Cluster 32: Basophils - Transcription" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 39: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 14 Nucleoplasm "HPA003719: " "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (2.30e-1)" "unprognostic (2.77e-2)" "unprognostic (1.49e-1)" "unprognostic (5.71e-3)" "unprognostic (2.94e-2)" "unprognostic (3.53e-2)" "unprognostic (8.06e-2)" "unprognostic (3.29e-3)" "potential prognostic favorable (1.18e-4)" "unprognostic (1.18e-2)" "unprognostic (1.50e-1)" "unprognostic (1.17e-1)" "unprognostic (3.25e-1)" "unprognostic (3.32e-2)" "unprognostic (4.92e-3)" "unprognostic (2.46e-3)" "unprognostic (8.26e-3)" "unprognostic (3.04e-1)" "potential prognostic favorable (9.11e-4)" "unprognostic (1.84e-2)" "unprognostic (3.24e-2)" "unprognostic (2.45e-2)" "unprognostic (2.63e-1)" "unprognostic (2.25e-1)" "potential prognostic unfavorable (8.57e-4)" "unprognostic (5.28e-2)" "unprognostic (4.98e-2)" "unprognostic (4.10e-3)" "unprognostic (1.37e-2)" ZNF302 "ZNF135L, ZNF140L, ZNF327" ENSG00000089335 "Zinc finger protein 302" Q9NR11 19 34677639-34686397 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Myonuclei: 181.4" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA045896 Approved Nucleoplasm NA No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 5 Nucleoplasm "HPA045896: " "unprognostic (2.13e-2)" "unprognostic (1.45e-1)" "unprognostic (3.80e-1)" "unprognostic (4.72e-1)" "unprognostic (4.67e-3)" "unprognostic (1.32e-2)" "unprognostic (2.37e-1)" "unprognostic (3.16e-2)" "unprognostic (2.48e-2)" "unprognostic (3.14e-1)" "unprognostic (8.88e-3)" "unprognostic (4.68e-3)" "unprognostic (4.45e-3)" "unprognostic (6.93e-2)" "unprognostic (2.71e-2)" "unprognostic (3.15e-2)" "unprognostic (6.35e-2)" "unprognostic (1.12e-1)" "unprognostic (2.16e-1)" "unprognostic (6.75e-2)" "unprognostic (1.68e-1)" "unprognostic (5.92e-3)" "unprognostic (8.66e-2)" "unprognostic (2.17e-1)" "unprognostic (1.01e-1)" "unprognostic (3.08e-2)" "unprognostic (2.99e-3)" "unprognostic (1.23e-2)" "unprognostic (9.41e-2)" "unprognostic (3.29e-2)" "unprognostic (5.29e-2)" ZNF32 "KOX30, Zfp637, ZNF637" ENSG00000169740 "Zinc finger protein 32" P17041 10 43643860-43648881 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 643 "Granulosa cells: 91407.6;T-cells: 37274.1" "Not detected" "Not detected" "HPA039148, HPA059640" Approved "Nucleoplasm,Nuclear bodies,Cytosol" Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 19: Astrocytes - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 97: Non-specific - Cellular respiration" 10 "Nucleoplasm, Nuclear bodies" Cytosol "HPA039148: , HPA059640: " "unprognostic (1.42e-1)" "potential prognostic unfavorable (2.37e-4)" "unprognostic (1.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.95e-2)" "unprognostic (1.40e-2)" "unprognostic (1.50e-2)" "unprognostic (2.66e-3)" "unprognostic (4.75e-2)" "unprognostic (1.50e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-1)" "unprognostic (8.38e-3)" "unprognostic (4.84e-3)" "unprognostic (1.11e-2)" "unprognostic (4.97e-2)" "unprognostic (1.70e-1)" "unprognostic (1.16e-2)" "unprognostic (1.25e-1)" "unprognostic (2.43e-3)" "unprognostic (2.17e-1)" "potential prognostic favorable (8.42e-4)" "unprognostic (2.03e-1)" "unprognostic (1.00e-1)" "unprognostic (2.14e-1)" "unprognostic (1.27e-1)" "unprognostic (7.85e-3)" "unprognostic (1.11e-1)" "unprognostic (1.27e-2)" "unprognostic (9.97e-2)" "unprognostic (3.67e-1)" ZNF324 "ZF5128, ZNF324A" ENSG00000083812 "Zinc finger protein 324" O75467 19 58467056-58475436 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Cell type enriched" "Detected in single" 4533 "Neurons: 453260.3" "Group enriched" "Detected in some" 86200 "fallopian tube: 10375103.2;lymphoid tissue: 6864944.7" HPA039774 Uncertain Approved "Nucleoplasm,Nuclear membrane,Cytosol" No No "Cluster 21: Neutrophils - Unknown function" "Cluster 2: Non-specific - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 6 "Nucleoplasm, Nuclear membrane, Cytosol" "HPA039774: " "unprognostic (3.77e-2)" "unprognostic (1.01e-1)" "unprognostic (1.28e-1)" "unprognostic (4.14e-2)" "unprognostic (2.25e-1)" "unprognostic (2.92e-2)" "unprognostic (1.66e-2)" "unprognostic (7.10e-3)" "unprognostic (4.48e-3)" "unprognostic (2.14e-1)" "potential prognostic favorable (7.97e-6)" "unprognostic (2.72e-3)" "unprognostic (8.87e-3)" "unprognostic (6.48e-2)" "unprognostic (2.95e-3)" "unprognostic (8.79e-2)" "unprognostic (4.05e-2)" "unprognostic (2.51e-2)" "unprognostic (4.39e-2)" "unprognostic (5.78e-2)" "unprognostic (4.54e-1)" "potential prognostic favorable (2.96e-4)" "unprognostic (1.71e-1)" "unprognostic (1.18e-2)" "unprognostic (4.38e-2)" "unprognostic (1.94e-1)" "unprognostic (2.71e-1)" "unprognostic (2.00e-1)" "unprognostic (1.57e-1)" "unprognostic (2.45e-3)" "unprognostic (7.39e-2)" ZNF326 "FLJ20403, ZAN75, Zfp326, ZIRD" ENSG00000162664 "Zinc finger protein 326" Q5BKZ1 1 89995110-90035533 "Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 48.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 389.2;Rod photoreceptor cells: 551.9" "Cell type enhanced" "Detected in all" "Neuronal cells: 551.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" "Granulosa cells: 35037917.8;Neurons: 103968306.3" "Tissue enhanced" "Detected in many" "intestine: 11061028.3" "HPA028450, HPA028461, HPA028466" Supported Approved "Nucleoplasm,Golgi apparatus,Vesicles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 56: Non-specific - Sensory perception" "Cluster 79: Photoreceptor cells - Phototransduction" 65 Nucleoplasm "Golgi apparatus, Vesicles" "HPA028450: , HPA028461: , HPA028466: " "unprognostic (8.05e-2)" "unprognostic (1.52e-1)" "unprognostic (2.13e-3)" "unprognostic (6.59e-3)" "unprognostic (9.44e-2)" "unprognostic (3.51e-2)" "unprognostic (4.06e-2)" "unprognostic (3.50e-2)" "potential prognostic favorable (3.41e-4)" "unprognostic (7.13e-2)" "unprognostic (3.91e-2)" "potential prognostic favorable (6.68e-4)" "unprognostic (8.19e-2)" "unprognostic (2.87e-1)" "unprognostic (7.63e-3)" "unprognostic (1.84e-1)" "unprognostic (5.33e-2)" "unprognostic (6.28e-2)" "unprognostic (4.43e-3)" "unprognostic (6.28e-2)" "unprognostic (1.52e-1)" "unprognostic (8.99e-2)" "unprognostic (9.71e-3)" "unprognostic (5.99e-2)" "potential prognostic favorable (1.30e-4)" "unprognostic (8.97e-2)" "unprognostic (1.39e-1)" "unprognostic (1.49e-2)" "unprognostic (5.08e-2)" "unprognostic (2.14e-2)" "unprognostic (2.61e-1)" ZNF330 "HSA6591, NOA36" ENSG00000109445 "Zinc finger protein 330" Q9Y3S2 4 141220887-141234697 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Decidual stromal cells: 160.6;Early spermatids: 241.3" "Cell type enhanced" "Detected in all" "Spermatogenic cell types: 241.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Neutrophils, Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 257282.2" "Tissue enhanced" "Detected in many" "bone marrow: 771573.6;heart muscle: 767627.6" "HPA015705, HPA056325" Uncertain Supported "Nucleoli,Plasma membrane,Primary cilium,Centrosome,Basal body,Cytosol" NA NA "Cluster 6: T-cells - T-cell receptor" "Cluster 41: Striated muscle - Muscle contraction" "Cluster 55: Non-specific - Transcription" "Cluster 22: Non-specific - mRNA splicing & Cell cycle" "Cluster 17: Non-specific - RNA processing" 50 Nucleoli "Plasma membrane, Primary cilium, Centrosome, Basal body, Cytosol" "HPA015705: , HPA056325: " "unprognostic (5.62e-2)" "unprognostic (2.71e-1)" "unprognostic (1.31e-1)" "unprognostic (2.76e-2)" "unprognostic (5.23e-2)" "unprognostic (2.52e-2)" "unprognostic (1.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (7.97e-3)" "validated prognostic favorable (1.06e-6)" "validated prognostic favorable (4.77e-4)" "unprognostic (4.58e-2)" "unprognostic (2.16e-2)" "unprognostic (3.92e-2)" "unprognostic (3.22e-2)" "unprognostic (1.23e-2)" "unprognostic (1.43e-1)" "unprognostic (9.14e-2)" "unprognostic (2.18e-1)" "unprognostic (8.97e-2)" "unprognostic (8.69e-2)" "unprognostic (1.12e-1)" "potential prognostic unfavorable (3.92e-5)" "unprognostic (3.56e-2)" "unprognostic (1.39e-2)" "unprognostic (3.83e-3)" "unprognostic (6.97e-2)" "unprognostic (1.42e-1)" "unprognostic (4.00e-3)" "unprognostic (1.63e-2)" ZNF33A "FLJ23404, KIAA0065, KOX31, KOX5, ZNF11A, ZNF33, ZZAPK" ENSG00000189180 "Zinc finger protein 33A" Q06730 10 38010650-38065088 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 384.6" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 35 "cerebral cortex: 3550.0" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 24: Neutrophils - Innate immunity signal integration" 2 "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: " "unprognostic (1.04e-3)" "unprognostic (7.53e-2)" "unprognostic (1.85e-1)" "unprognostic (2.46e-1)" "potential prognostic unfavorable (9.77e-5)" "unprognostic (4.83e-2)" "unprognostic (2.75e-2)" "unprognostic (1.42e-3)" "unprognostic (1.90e-2)" "unprognostic (1.82e-3)" "potential prognostic favorable (2.75e-5)" "unprognostic (1.89e-2)" "unprognostic (1.77e-1)" "potential prognostic unfavorable (7.22e-4)" "unprognostic (2.86e-2)" "unprognostic (5.58e-2)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (2.13e-1)" "unprognostic (2.51e-1)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (1.30e-1)" "unprognostic (7.46e-2)" "unprognostic (1.64e-1)" "unprognostic (4.77e-2)" "unprognostic (8.37e-2)" "unprognostic (1.92e-2)" "unprognostic (2.27e-1)" "unprognostic (4.77e-2)" "unprognostic (9.28e-2)" "unprognostic (1.93e-1)" ZNF33B "KOX2, KOX31, ZNF11B" ENSG00000196693 "Zinc finger protein 33B" Q06732 10 42574185-42638570 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005538, HPA056638" Approved Approved "Nucleoli fibrillar center,Endoplasmic reticulum,Vesicles" NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 60: Stomach - Digestion" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 52: Non-specific - Mitochondria" "Cluster 7: Non-specific - Transcription" 4 "Nucleoli fibrillar center, Endoplasmic reticulum" Vesicles "HPA005538: , HPA056638: " "unprognostic (1.34e-1)" "unprognostic (1.27e-2)" "unprognostic (6.75e-2)" "unprognostic (1.01e-3)" "unprognostic (8.46e-3)" "unprognostic (1.22e-1)" "unprognostic (1.84e-2)" "potential prognostic favorable (2.13e-4)" "unprognostic (4.20e-2)" "unprognostic (3.22e-2)" "validated prognostic favorable (1.49e-8)" "validated prognostic favorable (2.77e-5)" "unprognostic (6.95e-2)" "unprognostic (1.89e-2)" "unprognostic (7.38e-2)" "unprognostic (9.84e-3)" "unprognostic (9.47e-2)" "unprognostic (2.01e-2)" "unprognostic (8.30e-2)" "unprognostic (1.38e-1)" "unprognostic (5.48e-2)" "unprognostic (2.77e-1)" "unprognostic (2.22e-1)" "unprognostic (6.03e-2)" "unprognostic (6.24e-3)" "unprognostic (2.84e-1)" "unprognostic (1.36e-1)" "unprognostic (1.14e-1)" "unprognostic (6.74e-2)" "unprognostic (2.02e-2)" "unprognostic (1.77e-1)" ZNF341 dJ553F4.3 ENSG00000131061 "Zinc finger protein 341" Q9BYN7 20 33731657-33792269 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Myonuclei: 31.8" "Cell type enhanced" "Detected in many" "Myocytes: 31.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023240, HPA024607, HPA067108" Uncertain Approved "Nucleoplasm,Nuclear bodies,Vesicles" Yes No "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 53: Neurons - Mixed function" "Cluster 24: Non-specific - Unknown function" "Cluster 36: Skeletal myocytes - Muscle excitation & contraction" 9 "Nucleoplasm, Vesicles" "Nuclear bodies" "HPA023240: , HPA024607: , HPA067108: " "unprognostic (1.87e-2)" "unprognostic (1.82e-3)" "unprognostic (1.60e-1)" "unprognostic (2.76e-2)" "unprognostic (1.59e-1)" "unprognostic (2.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-2)" "unprognostic (2.31e-3)" "unprognostic (1.43e-1)" "unprognostic (2.91e-1)" "potential prognostic unfavorable (2.02e-6)" "unprognostic (2.06e-1)" "unprognostic (1.24e-2)" "unprognostic (7.51e-3)" "unprognostic (8.50e-2)" "unprognostic (3.06e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (2.46e-1)" "unprognostic (1.13e-2)" "unprognostic (2.11e-1)" "unprognostic (8.40e-3)" "unprognostic (3.01e-2)" "unprognostic (7.67e-2)" "unprognostic (1.15e-1)" "unprognostic (3.96e-1)" "unprognostic (3.13e-1)" "unprognostic (9.78e-2)" ZNF354A "EZNF, HKL1, KID-1, KID1, TCF17" ENSG00000169131 "Zinc finger protein 354A" O60765 5 178711512-178730659 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bergmann glia: 23.8;Microglia: 27.0;Proximal tubule cells: 23.3" "Cell type enhanced" "Detected in many" "Glial cells: 27.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 51 "Granulosa cells: 5101.1" "Tissue enriched" "Detected in single" 2340 "intestine: 234044.5" HPA052043 Approved Supported Nucleoplasm,Nucleoli,Cytosol NA NA "Cluster 21: Neutrophils - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 48: Neutrophils - Phagocytosis & degranulation" 7 "Nucleoplasm, Nucleoli" Cytosol "HPA052043: " "unprognostic (4.98e-2)" "unprognostic (1.06e-1)" "unprognostic (1.91e-1)" "unprognostic (1.36e-1)" "unprognostic (2.96e-2)" "unprognostic (5.00e-2)" "unprognostic (4.32e-2)" "unprognostic (6.94e-2)" "unprognostic (9.15e-2)" "potential prognostic unfavorable (2.98e-4)" "unprognostic (2.41e-1)" "unprognostic (6.05e-2)" "unprognostic (1.72e-2)" "unprognostic (2.70e-2)" "unprognostic (4.70e-2)" "unprognostic (1.31e-1)" "unprognostic (2.02e-1)" "unprognostic (1.96e-2)" "unprognostic (1.13e-1)" "unprognostic (1.80e-1)" "unprognostic (3.33e-2)" "unprognostic (7.28e-2)" "unprognostic (3.70e-3)" "unprognostic (1.32e-1)" "unprognostic (8.09e-2)" "unprognostic (6.36e-2)" "unprognostic (8.77e-2)" "unprognostic (1.63e-1)" "unprognostic (2.36e-1)" "unprognostic (5.86e-3)" "unprognostic (9.45e-2)" ZNF354C KID3 ENSG00000177932 "Zinc finger protein 354C" Q86Y25 5 179060373-179083977 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 36.1;Cardiomyocytes: 30.1" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030904, HPA068570" Uncertain Supported Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 1 Nucleoplasm "HPA030904: , HPA068570: " "unprognostic (5.63e-2)" "unprognostic (1.83e-1)" "unprognostic (8.41e-2)" "unprognostic (1.33e-1)" "unprognostic (2.38e-1)" "unprognostic (4.58e-1)" "potential prognostic favorable (1.21e-4)" "unprognostic (9.04e-3)" "unprognostic (8.83e-2)" "unprognostic (6.68e-3)" "unprognostic (6.96e-2)" "unprognostic (1.60e-2)" "unprognostic (1.63e-1)" "unprognostic (5.90e-2)" "unprognostic (3.69e-2)" "unprognostic (7.19e-2)" "unprognostic (4.07e-1)" "unprognostic (1.11e-1)" "unprognostic (2.89e-1)" "unprognostic (2.97e-2)" "unprognostic (1.17e-1)" "unprognostic (3.16e-2)" "unprognostic (4.21e-3)" ZNF358 "FLJ10390, ZFEND" ENSG00000198816 "Zinc finger protein 358" Q9NW07 19 7515292-7521025 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Granulosa cells: 6043099.8" "Tissue enriched" "Detected in some" "lymphoid tissue: 1798351.5" "HPA030887, HPA063624" Approved Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 23: Non-specific - Transcription" "Cluster 17: Non-specific - RNA processing" Nucleoplasm "HPA030887: , HPA063624: " "unprognostic (6.10e-2)" "unprognostic (7.13e-2)" "unprognostic (2.44e-1)" "unprognostic (9.74e-3)" "unprognostic (7.90e-2)" "unprognostic (1.00e-1)" "unprognostic (1.31e-1)" "unprognostic (3.14e-1)" "unprognostic (2.28e-1)" "unprognostic (1.02e-1)" "unprognostic (3.43e-2)" "unprognostic (6.93e-2)" "unprognostic (4.05e-2)" "unprognostic (1.87e-2)" "unprognostic (2.66e-1)" "unprognostic (7.00e-2)" "unprognostic (3.53e-2)" "unprognostic (2.85e-2)" "unprognostic (1.04e-1)" "unprognostic (2.11e-2)" "unprognostic (1.51e-1)" "unprognostic (2.50e-3)" "unprognostic (2.27e-1)" "unprognostic (1.54e-1)" "unprognostic (1.33e-1)" "unprognostic (2.11e-2)" "unprognostic (1.41e-1)" "unprognostic (8.16e-2)" "unprognostic (9.94e-2)" "unprognostic (7.96e-2)" "unprognostic (2.04e-2)" ZNF383 "FLJ35863, Zfp383" ENSG00000188283 "Zinc finger protein 383" Q8NA42 19 37217926-37248740 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 60.7;Myonuclei: 73.8" "Cell type enhanced" "Detected in many" "Myocytes: 73.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA063945 Approved Supported "Nucleoplasm,Nuclear membrane" No No "Cluster 24: Non-specific - Transcription" "Cluster 61: Non-specific - Transcription" "Cluster 38: Sub-cortical - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 55: Myocytes - Oxidative muscle function" 5 "Nucleoplasm, Nuclear membrane" "HPA063945: " "potential prognostic favorable (2.13e-4)" "unprognostic (6.68e-2)" "unprognostic (9.11e-2)" "unprognostic (3.03e-2)" "unprognostic (2.35e-1)" "unprognostic (1.56e-1)" "unprognostic (1.23e-2)" "unprognostic (4.56e-2)" "unprognostic (3.41e-2)" "unprognostic (2.04e-2)" "unprognostic (1.06e-3)" "potential prognostic favorable (5.98e-4)" "unprognostic (5.29e-3)" "unprognostic (5.54e-2)" "unprognostic (1.56e-1)" "unprognostic (3.05e-2)" "unprognostic (3.67e-2)" "unprognostic (1.77e-1)" "unprognostic (5.16e-2)" "unprognostic (1.18e-2)" "unprognostic (7.91e-2)" "unprognostic (7.04e-2)" "unprognostic (7.16e-3)" "unprognostic (2.52e-1)" "potential prognostic favorable (7.24e-5)" "unprognostic (2.15e-2)" "potential prognostic unfavorable (5.89e-4)" "unprognostic (1.29e-1)" "unprognostic (4.07e-2)" "unprognostic (5.13e-3)" "unprognostic (1.16e-1)" ZNF394 "FLJ12298, ZKSCAN14, ZSCAN46" ENSG00000160908 "Zinc finger protein 394" Q53GI3 7 99473877-99504857 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 91.4" "Cell type enhanced" "Detected in many" "Neutrophil progenitors: 164.7;Neutrophils: 273.3" "Cell type enhanced" "Detected in all" "Neutrophils: 273.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051421, HPA054639" Approved Enhanced Nucleoplasm,Cytosol Yes No "Cluster 42: Non-specific - Vesicular transport" "Cluster 15: Bone marrow - Innate immune response" "Cluster 25: Non-specific - Transcription" "Cluster 39: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 7 Nucleoplasm Cytosol "HPA051421: , HPA054639: " "unprognostic (8.57e-3)" "unprognostic (1.01e-3)" "unprognostic (1.19e-1)" "unprognostic (6.89e-2)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (3.49e-2)" "unprognostic (2.89e-2)" "unprognostic (3.78e-3)" "unprognostic (1.17e-2)" "unprognostic (7.34e-3)" "potential prognostic favorable (2.79e-4)" "unprognostic (1.39e-1)" "unprognostic (4.82e-1)" "unprognostic (3.54e-2)" "unprognostic (1.10e-2)" "unprognostic (7.26e-3)" "unprognostic (4.30e-3)" "unprognostic (9.03e-2)" "unprognostic (3.10e-1)" "unprognostic (3.34e-2)" "unprognostic (2.98e-1)" "unprognostic (2.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (2.65e-1)" "unprognostic (5.23e-2)" "unprognostic (2.81e-2)" "unprognostic (2.62e-2)" "unprognostic (3.38e-2)" "unprognostic (2.40e-3)" ZNF416 FLJ20557 ENSG00000083817 "Zinc finger protein 416" Q9BWM5 19 57571566-57578911 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Esophageal apical cells: 26.8;Late primary spermatocytes: 8.6;Oocytes: 18.4" "Cell type enhanced" "Detected in many" "Apical squamous epithelial cells: 26.8;Oocytes: 18.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Skin - Keratinocyte (other)" "Not detected" "Not detected" "Not detected" "Not detected" HPA078491 Approved "Nucleoplasm,Nuclear speckles" NA No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" Nucleoplasm "Nuclear speckles" "HPA078491: " "unprognostic (2.79e-1)" "unprognostic (2.20e-1)" "unprognostic (1.07e-1)" "unprognostic (2.37e-1)" "unprognostic (4.18e-2)" "unprognostic (9.08e-3)" "unprognostic (7.68e-2)" "unprognostic (2.31e-1)" "unprognostic (2.74e-2)" "unprognostic (9.73e-2)" "validated prognostic favorable (5.66e-9)" "validated prognostic favorable (3.19e-5)" "unprognostic (3.49e-2)" "unprognostic (1.60e-2)" "unprognostic (5.15e-2)" "unprognostic (3.44e-1)" "unprognostic (6.02e-2)" "unprognostic (2.45e-2)" "unprognostic (1.51e-1)" "unprognostic (1.11e-1)" "unprognostic (1.41e-1)" "unprognostic (2.10e-2)" "unprognostic (1.35e-1)" "unprognostic (2.43e-2)" "unprognostic (1.15e-3)" "unprognostic (3.23e-2)" "unprognostic (1.69e-1)" "unprognostic (1.44e-1)" "unprognostic (2.46e-1)" "unprognostic (2.16e-2)" "unprognostic (2.40e-1)" ZNF418 "FLJ31551, KIAA1956" ENSG00000196724 "Zinc finger protein 418" Q8TF45 19 57921882-57935402 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 22.2" "Cell type enhanced" "Detected in many" "Myocytes: 22.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 10.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Skeletal muscle - Fibroblasts" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043800, HPA053762, HPA072145" Approved Uncertain Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 2 Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (5.86e-2)" "unprognostic (1.58e-1)" "unprognostic (9.32e-2)" "unprognostic (3.68e-1)" "unprognostic (3.03e-1)" "unprognostic (4.06e-2)" "unprognostic (2.58e-1)" "validated prognostic favorable (2.99e-4)" "validated prognostic favorable (5.46e-4)" "potential prognostic favorable (5.92e-4)" "unprognostic (9.08e-2)" "unprognostic (6.52e-2)" "unprognostic (1.21e-1)" "unprognostic (1.07e-1)" "unprognostic (3.34e-1)" "unprognostic (1.92e-1)" "unprognostic (2.25e-1)" "unprognostic (1.39e-2)" "unprognostic (1.70e-2)" "unprognostic (7.03e-3)" "unprognostic (3.20e-1)" "unprognostic (2.37e-2)" "unprognostic (6.64e-2)" "unprognostic (2.15e-1)" "unprognostic (2.63e-1)" "unprognostic (2.75e-2)" ZNF426 MGC2663 ENSG00000130818 "Zinc finger protein 426" Q9BUY5 19 9523223-9538645 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in many" 9 "Esophageal apical cells: 413.6" "Cell type enriched" "Detected in many" 9 "Apical squamous epithelial cells: 413.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Spleen - Endothelial cells" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 198 "Proximal tubules: 19827.0" "Not detected" "Not detected" HPA029342 Approved Approved Nucleoplasm Yes No "Cluster 15: NK-cells - Unknown function" "Cluster 81: Squamous epithelium - Keratinization" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 49: Apical squamous epithelium - Epithelial barrier & keratinization" 35 Nucleoplasm "HPA029342: " "unprognostic (4.64e-3)" "unprognostic (2.07e-1)" "unprognostic (9.55e-2)" "unprognostic (4.71e-2)" "unprognostic (3.94e-1)" "unprognostic (6.39e-2)" "unprognostic (1.39e-1)" "unprognostic (1.37e-1)" "potential prognostic favorable (9.20e-4)" "unprognostic (1.25e-2)" "validated prognostic favorable (8.42e-6)" "validated prognostic favorable (1.91e-4)" "potential prognostic favorable (6.50e-4)" "unprognostic (9.01e-2)" "unprognostic (2.42e-1)" "unprognostic (6.34e-2)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (3.32e-2)" "unprognostic (9.14e-2)" "unprognostic (2.15e-2)" "unprognostic (9.70e-2)" "unprognostic (4.89e-2)" "unprognostic (4.54e-2)" "potential prognostic favorable (1.07e-4)" "unprognostic (1.71e-3)" "unprognostic (6.00e-3)" "unprognostic (1.15e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" ZNF433 FLJ40981 ENSG00000197647 "Zinc finger protein 433" Q8N7K0 19 12014715-12035741 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 20.4" "Cell type enhanced" "Detected in many" "Early spermatids: 205.4;Late primary spermatocytes: 140.0;Late spermatids: 175.3;Oocytes: 46.1" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 205.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" HPA073724 Enhanced Approved "Nuclear bodies" "Intracellular and membrane" Transcription NA NA "Cluster 10: Non-specific - Membrane trafficking" "Cluster 72: Kidney - Transmembrane transport" "Cluster 35: Non-specific - DNA binding" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 9 "Nuclear bodies" "HPA073724: " "unprognostic (2.92e-3)" "unprognostic (7.23e-2)" "unprognostic (2.41e-1)" "unprognostic (6.99e-2)" "unprognostic (4.73e-2)" "unprognostic (1.10e-1)" "unprognostic (2.76e-1)" "unprognostic (2.44e-1)" "unprognostic (6.52e-2)" "potential prognostic unfavorable (8.38e-4)" "validated prognostic favorable (3.43e-4)" "validated prognostic favorable (7.63e-6)" "potential prognostic favorable (2.75e-5)" "unprognostic (2.62e-1)" "unprognostic (1.10e-2)" "unprognostic (5.51e-2)" "unprognostic (4.51e-2)" "unprognostic (3.16e-1)" "unprognostic (7.47e-2)" "unprognostic (5.98e-2)" "unprognostic (7.02e-2)" "unprognostic (5.09e-2)" "unprognostic (1.41e-1)" "unprognostic (8.86e-3)" "unprognostic (6.67e-2)" "unprognostic (2.37e-2)" "unprognostic (4.24e-2)" "unprognostic (1.04e-1)" "unprognostic (5.09e-2)" "unprognostic (1.47e-2)" "unprognostic (2.22e-1)" ZNF444 "EZF2, FLJ11137, ZSCAN17" ENSG00000167685 "Zinc finger protein 444" Q8N0Y2 19 56132599-56160893 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 48 "Fallopian tube cells: 4762.6" "Tissue enriched" "Detected in single" 61852 "salivary gland: 6185185.2" "HPA056895, HPA065203" Approved Enhanced Nucleoplasm,Nucleoli Yes No "Cluster 3: Non-specific - Nuclear processes" "Cluster 70: Non-specific - Protein processing" "Cluster 18: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 54: Intestinal epithelial cells - Intestinal epi homeostasis & respiration" 3 Nucleoplasm Nucleoli "HPA056895: , HPA065203: " "unprognostic (2.23e-3)" "unprognostic (3.15e-2)" "unprognostic (2.80e-2)" "unprognostic (2.19e-2)" "unprognostic (1.67e-1)" "unprognostic (7.46e-2)" "unprognostic (2.05e-1)" "unprognostic (1.13e-2)" "unprognostic (1.33e-1)" "unprognostic (7.89e-2)" "unprognostic (4.78e-2)" "unprognostic (9.68e-2)" "unprognostic (4.42e-2)" "unprognostic (1.98e-3)" "unprognostic (1.63e-1)" "unprognostic (1.53e-1)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (3.80e-1)" "unprognostic (1.32e-1)" "unprognostic (7.42e-3)" "unprognostic (2.78e-1)" "unprognostic (4.88e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-1)" "unprognostic (1.14e-1)" "unprognostic (2.05e-2)" "unprognostic (3.09e-1)" "unprognostic (7.35e-2)" "unprognostic (1.44e-1)" ZNF48 "DKFZp762K013, FLJ31751, MGC43952, ZNF553" ENSG00000180035 "Zinc finger protein 48" Q96MX3 16 30378106-30400108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "B-cells: 29132.5;Granulosa cells: 57518.7;T-cells: 59978.0" "Tissue enriched" "Detected in single" 9920 "lymphoid tissue: 991981.1" HPA023806 Uncertain Approved Mitochondria No No "Cluster 27: T-cells - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 34: Non-specific - Mixed function" "Cluster 54: Non-specific - Transcription" "Cluster 9: T-cells - Adaptive immunity: Regulation" 21 Mitochondria "HPA023806: " "unprognostic (1.62e-2)" "unprognostic (3.49e-1)" "unprognostic (7.16e-2)" "unprognostic (3.59e-2)" "unprognostic (2.10e-2)" "unprognostic (2.18e-1)" "unprognostic (3.22e-2)" "potential prognostic favorable (6.16e-6)" "unprognostic (1.55e-1)" "unprognostic (7.99e-2)" "potential prognostic favorable (8.63e-5)" "unprognostic (2.30e-2)" "unprognostic (2.61e-3)" "unprognostic (2.12e-3)" "unprognostic (1.06e-2)" "unprognostic (2.34e-1)" "unprognostic (3.17e-2)" "unprognostic (2.00e-1)" "unprognostic (2.19e-2)" "unprognostic (1.61e-1)" "unprognostic (4.63e-2)" "potential prognostic favorable (5.03e-4)" "unprognostic (4.81e-1)" "unprognostic (6.90e-2)" "unprognostic (4.11e-3)" "unprognostic (4.37e-1)" "unprognostic (2.63e-1)" "unprognostic (1.28e-1)" "unprognostic (2.67e-1)" "unprognostic (9.47e-2)" "unprognostic (3.74e-3)" ZNF487 "KRBO1, ZNF487P" ENSG00000243660 "Zinc finger protein 487" 10 43436841-43483181 "Essential proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.2" "Cell type enhanced" "Detected in many" "Early spermatids: 235.8;Ependymal cells: 122.8;Late spermatids: 440.5;Respiratory ciliated cells: 146.0" "Cell type enhanced" "Detected in many" "Ciliated cells: 146.0;Spermatogenic cell types: 440.5" "Cell type enhanced" "Detected in all" "ependymal cell: 131.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Adipose subcutaneous - Adipose progenitor cells, Lung - Respiratory ciliated cells, Testis - Early spermatids, Testis - Late spermatids" HPA037820 Approved "Nucleoplasm,Nuclear membrane,Cytosol" Yes No "Cluster 28: Neutrophils - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 17: Choroid plexus - Cilium" "Cluster 52: Non-specific - Mitochondria" "Cluster 73: Late spermatids - Spermiogenesis: Maturation" "Nuclear membrane" "Nucleoplasm, Cytosol" "HPA037820: " "unprognostic (3.98e-2)" "unprognostic (1.47e-3)" "unprognostic (3.68e-2)" "unprognostic (3.04e-3)" "unprognostic (1.90e-1)" "unprognostic (7.48e-2)" "unprognostic (9.45e-2)" "unprognostic (6.93e-2)" "unprognostic (2.64e-3)" "unprognostic (4.58e-2)" "unprognostic (1.09e-1)" "unprognostic (3.54e-2)" "unprognostic (1.24e-1)" "unprognostic (2.21e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (1.89e-2)" "unprognostic (6.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.36e-2)" "unprognostic (3.86e-1)" "unprognostic (4.53e-2)" "unprognostic (8.24e-2)" "unprognostic (5.24e-2)" "unprognostic (8.59e-3)" "unprognostic (2.72e-2)" "unprognostic (1.81e-1)" "unprognostic (5.87e-2)" "unprognostic (4.90e-3)" "unprognostic (1.99e-1)" ZNF518A "KIAA0335, ZNF518" ENSG00000177853 "Zinc finger protein 518A" Q6AHZ1 10 96129715-96205288 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 684.9" "Cell type enhanced" "Detected in all" "Reproductive supporting cells: 684.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low tissue specificity" "Detected in many" HPA029049 Approved Nucleoplasm Yes No "Cluster 35: Neutrophils - Protein binding" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 26: Oligodendrocytes - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 3 Nucleoplasm "HPA029049: " "unprognostic (1.24e-1)" "unprognostic (4.18e-2)" "unprognostic (5.05e-2)" "unprognostic (3.03e-2)" "unprognostic (1.57e-1)" "unprognostic (4.95e-1)" "unprognostic (6.54e-2)" "unprognostic (1.54e-3)" "unprognostic (7.36e-3)" "unprognostic (3.35e-1)" "unprognostic (3.40e-3)" "unprognostic (8.01e-3)" "unprognostic (2.23e-2)" "unprognostic (6.39e-2)" "unprognostic (1.67e-2)" "unprognostic (5.54e-2)" "unprognostic (1.10e-1)" "unprognostic (2.52e-1)" "unprognostic (4.44e-2)" "unprognostic (1.95e-1)" "unprognostic (1.52e-1)" "unprognostic (1.10e-1)" "unprognostic (2.84e-2)" "unprognostic (2.84e-2)" "unprognostic (1.20e-3)" "unprognostic (1.84e-1)" "unprognostic (9.55e-2)" "unprognostic (1.72e-1)" "unprognostic (3.88e-1)" "potential prognostic unfavorable (1.68e-4)" "unprognostic (3.11e-1)" ZNF528 KIAA1827 ENSG00000167555 "Zinc finger protein 528" Q3MIS6 19 52397849-52418412 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA065435 Approved "Nuclear speckles,Cytosol" No No "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 22: Epididymis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 91: Pituicytes/FSC - Homeostasis & neuron support" "Nuclear speckles" Cytosol "HPA065435: " "unprognostic (4.85e-3)" "unprognostic (4.44e-2)" "unprognostic (9.75e-2)" "unprognostic (1.60e-3)" "unprognostic (1.36e-1)" "unprognostic (3.91e-2)" "unprognostic (8.28e-2)" "unprognostic (1.65e-1)" "unprognostic (1.25e-1)" "unprognostic (6.05e-3)" "unprognostic (1.59e-2)" "unprognostic (1.77e-3)" "unprognostic (2.57e-3)" "unprognostic (2.05e-2)" "unprognostic (5.04e-2)" "unprognostic (1.14e-1)" "unprognostic (8.48e-2)" "unprognostic (2.25e-1)" "unprognostic (1.11e-1)" "unprognostic (1.67e-2)" "unprognostic (5.64e-2)" "unprognostic (1.53e-1)" "unprognostic (1.37e-2)" "unprognostic (4.32e-1)" "unprognostic (3.17e-1)" "unprognostic (3.42e-1)" "potential prognostic unfavorable (2.29e-4)" "unprognostic (1.14e-2)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (1.20e-1)" ZNF534 "FLJ25344, KRBO3" ENSG00000198633 "Zinc finger protein 534" Q76KX8 19 52429148-52452315 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 2.4;retina: 1.0;testis: 1.8" "Cell type enhanced" "Detected in some" "Bergmann glia: 5.6;Brain excitatory neurons: 7.9;Brain inhibitory neurons: 10.7;Differentiating spermatogonia: 22.0;Early primary spermatocytes: 12.5;Oocytes: 18.4;Retinal amacrine cells: 12.3;Retinal horizontal cells: 8.0;Undifferentiated spermatogonia: 12.2" "Cell type enhanced" "Detected in some" "Neuronal cells: 12.3;Oocytes: 18.4;Spermatogenic cell types: 22.0" "Low cell type specificity" "Detected in many" "Cancer enriched" "Detected in single" 17 "Testicular Germ Cell Tumor (TCGA): 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 20 "Adrenocortical cancer: 16.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA078521 Approved Mitochondria NA NA "Cluster 10: Brain - Synaptic signal transduction" "Cluster 34: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 35: Neurons - Synaptic function & neurogenesis" 3 Mitochondria "HPA078521: " "unprognostic (1.67e-1)" "unprognostic (1.36e-2)" "unprognostic (1.85e-1)" ZNF536 KIAA0390 ENSG00000198597 "Zinc finger protein 536" O15090 19 30224891-30713586 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 30.4;retina: 8.8" "Cell type enhanced" "Detected in many" "Bergmann glia: 424.0;Brain inhibitory neurons: 259.7;Choroid plexus epithelial cells: 995.1;Lactotrophs: 394.3;Müller glia: 526.9;Oligodendrocytes: 1122.5;Retinal bipolar cells: 311.0;Retinal horizontal cells: 354.6;Retinal pigment epithelial cells: 754.5;Schwann cells: 465.8;Sertoli cells: 377.2;Somatotrophs: 500.0;Thyrotrophs: 339.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 995.1;Glial cells: 1122.5;Neuronal cells: 354.6;Pigment cells: 754.5;Pituitary endocrine cells: 500.0;Reproductive supporting cells: 377.2" "Cell type enhanced" "Detected in all" "LAMP5-LHX6 and Chandelier: 1408.0;oligodendrocyte: 1374.0" "Cancer enhanced" "Detected in some" "Glioblastoma Multiforme (TCGA): 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Neuroblastoma: 9.5" "Adipose subcutaneous - Smooth muscle cells, Adipose visceral - Smooth muscle cells, Colon - Enteric glia cells, Prostate - Fibroblasts, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 2962 "Neurons: 296225.5" "Tissue enriched" "Detected in single" 275 "bone marrow: 27520.2" HPA077341 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Oligodendrocytes - Myelination" "Cluster 11: White matter - Signal transduction" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 80: Oligodendrocytes - Myelination" 7 "Nucleoplasm, Cell Junctions" "HPA077341: " "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.38e-1)" "unprognostic (1.82e-1)" "unprognostic (7.57e-2)" "unprognostic (2.20e-1)" "unprognostic (4.25e-2)" ZNF552 FLJ21603 ENSG00000178935 "Zinc finger protein 552" Q9H707 19 57803841-57814913 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 125.8;Prostatic club cells: 221.0;Prostatic hillock cells: 261.7" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 261.7;Glandular cells: 221.0" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in all" "Breast Invasive Carcinoma (TCGA): 57.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.4" "Lineage enriched" "Detected in all" 6 "granulocytes: 25.4" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043800, HPA053762, HPA072145" Uncertain Uncertain Nucleoplasm NA NA "Cluster 35: Neutrophils - Protein binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 48: Non-specific - Mixed function" "Cluster 27: Breast cancer - Unknown function" "Cluster 24: Neutrophils - Innate immunity signal integration" 31 Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (1.37e-3)" "unprognostic (8.99e-3)" "unprognostic (1.29e-1)" "unprognostic (9.60e-2)" "unprognostic (1.61e-1)" "unprognostic (9.78e-2)" "unprognostic (2.34e-1)" "unprognostic (3.12e-1)" "unprognostic (1.12e-3)" "unprognostic (2.54e-2)" "unprognostic (1.05e-1)" "potential prognostic favorable (8.14e-5)" "unprognostic (5.15e-3)" "unprognostic (1.15e-1)" "unprognostic (3.40e-1)" "potential prognostic favorable (4.23e-4)" "unprognostic (1.19e-1)" "unprognostic (7.54e-2)" "unprognostic (1.39e-1)" "unprognostic (2.03e-1)" "unprognostic (1.80e-1)" "unprognostic (1.12e-1)" "unprognostic (1.23e-1)" "unprognostic (2.06e-1)" "potential prognostic favorable (1.02e-4)" "unprognostic (4.01e-1)" "unprognostic (5.87e-2)" "unprognostic (1.94e-2)" "unprognostic (1.71e-1)" "unprognostic (4.88e-3)" "unprognostic (1.63e-2)" ZNF554 FLJ34817 ENSG00000172006 "Zinc finger protein 554" Q86TJ5 19 2819868-2836735 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Syncytiotrophoblasts: 23.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Breast - Breast glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060247, HPA063358" Uncertain Enhanced Nucleoplasm,Nucleoli No No "Cluster 2: Non-specific - Mixed function" "Cluster 24: Neurons - Mixed function" "Cluster 6: Leukemia - Signal transduction" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 6 Nucleoplasm Nucleoli "HPA060247: , HPA063358: " "unprognostic (1.51e-2)" "unprognostic (7.22e-2)" "unprognostic (1.13e-1)" "unprognostic (7.60e-2)" "unprognostic (1.32e-1)" "unprognostic (8.76e-3)" "unprognostic (1.86e-1)" "unprognostic (2.85e-1)" "unprognostic (2.20e-1)" "unprognostic (9.38e-3)" "unprognostic (1.38e-2)" "unprognostic (8.18e-2)" "unprognostic (2.29e-2)" "unprognostic (1.58e-2)" "unprognostic (2.59e-1)" "unprognostic (2.12e-3)" "unprognostic (3.77e-2)" "unprognostic (5.60e-2)" "potential prognostic favorable (2.78e-5)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (3.41e-2)" "unprognostic (4.68e-2)" "unprognostic (3.55e-2)" "unprognostic (2.63e-1)" "unprognostic (4.23e-1)" "unprognostic (1.79e-1)" "unprognostic (2.63e-1)" ZNF557 MGC4054 ENSG00000130544 "Zinc finger protein 557" Q8N988 19 7069703-7087968 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA003151, HPA029291" Uncertain Approved "Nucleoplasm,Intermediate filaments" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 23: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "HPA003151: , HPA029291: " "unprognostic (4.86e-3)" "unprognostic (1.28e-2)" "unprognostic (1.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.69e-1)" "unprognostic (1.25e-1)" "unprognostic (3.13e-2)" "unprognostic (1.49e-1)" "potential prognostic favorable (7.22e-7)" "unprognostic (6.68e-3)" "unprognostic (6.53e-3)" "potential prognostic favorable (2.43e-4)" "unprognostic (6.13e-2)" "unprognostic (1.20e-1)" "unprognostic (4.95e-2)" "unprognostic (1.32e-3)" "unprognostic (1.08e-1)" "unprognostic (9.55e-2)" "potential prognostic favorable (9.16e-5)" "unprognostic (1.88e-1)" "unprognostic (5.86e-2)" "unprognostic (2.07e-3)" "unprognostic (2.45e-1)" "unprognostic (4.07e-2)" "unprognostic (2.11e-3)" "unprognostic (9.16e-3)" "unprognostic (3.91e-2)" "unprognostic (1.94e-2)" "unprognostic (1.59e-1)" "unprognostic (1.66e-1)" "unprognostic (6.81e-2)" ZNF560 FLJ31986 ENSG00000198028 "Zinc finger protein 560" Q96MR9 19 9466355-9498616 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 1.9;testis: 5.8" "Cell type enhanced" "Detected in some" "Differentiating spermatogonia: 18.3;Early primary spermatocytes: 22.7;Early spermatids: 62.4;Late primary spermatocytes: 85.9;Late spermatids: 16.7;Oocytes: 50.7;Rod photoreceptor cells: 12.5;Sertoli cells: 22.5;Undifferentiated spermatogonia: 14.1" "Group enriched" "Detected in some" 4 "Oocytes: 50.7;Reproductive supporting cells: 22.5;Spermatogenic cell types: 85.9" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 10 "Testicular Germ Cell Tumor (TCGA): 12.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "Adrenocortical cancer: 7.2;testis cancer: 8.5" "Cell type enriched" "Detected in single" 5119 "Keratinocytes: 511850.7" "Not detected" "Not detected" "HPA045439, HPA074438" Enhanced "Nucleoplasm,Nuclear speckles" NA NA "Cluster 47: Testis - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" Nucleoplasm "Nuclear speckles" "HPA045439: , HPA074438: " "unprognostic (5.14e-3)" "potential prognostic favorable (1.08e-5)" "unprognostic (4.31e-2)" "unprognostic (6.43e-2)" "unprognostic (9.16e-3)" "unprognostic (1.72e-1)" ZNF563 FLJ34797 ENSG00000188868 "Zinc finger protein 563" Q8TA94 19 12317477-12333720 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 13.5" "Cell type enhanced" "Detected in many" "Early spermatids: 183.9;Late primary spermatocytes: 156.0;Müller glia: 42.6;Sertoli cells: 49.9" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 183.9" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 4.2;T-cells: 8.9" "Low cancer specificity" "Detected in many" "Prostate - Prostate glandular cells, Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 15 "lymphoid tissue: 1487.8" HPA042136 Uncertain Approved Vesicles NA NA "Cluster 43: Non-specific - Transcription & Translation" "Cluster 47: Testis - Mixed function" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 1 Vesicles "HPA042136: " "potential prognostic favorable (3.44e-4)" "unprognostic (1.72e-2)" "unprognostic (5.11e-3)" "unprognostic (1.02e-1)" "unprognostic (2.18e-1)" "unprognostic (1.83e-2)" "unprognostic (1.49e-1)" "unprognostic (7.86e-2)" "unprognostic (2.52e-1)" "unprognostic (5.54e-3)" "validated prognostic favorable (1.11e-5)" "validated prognostic favorable (7.65e-4)" "potential prognostic favorable (5.77e-4)" "unprognostic (4.35e-2)" "unprognostic (7.88e-3)" "unprognostic (1.47e-2)" "unprognostic (2.02e-1)" "unprognostic (1.83e-1)" "unprognostic (2.05e-1)" "unprognostic (2.11e-1)" "unprognostic (2.15e-2)" "unprognostic (1.94e-1)" "unprognostic (3.39e-1)" "unprognostic (5.24e-1)" "unprognostic (4.26e-2)" "unprognostic (5.23e-3)" "unprognostic (1.07e-2)" "unprognostic (5.88e-2)" "unprognostic (5.75e-1)" "unprognostic (1.86e-1)" "unprognostic (5.65e-2)" ZNF568 DKFZp686B0797 ENSG00000198453 "Zinc finger protein 568" Q3ZCX4 19 36916316-37005037 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 35.8;Bergmann glia: 46.6;Brain excitatory neurons: 39.6;Brain inhibitory neurons: 39.2;Choroid plexus epithelial cells: 55.8;Distal convoluted tubule cells: 32.0;Oligodendrocyte progenitor cells: 48.3;Oligodendrocytes: 43.6;Other brain neurons: 44.5;Podocytes: 40.5" "Cell type enhanced" "Detected in many" "Ciliated cells: 55.8;Glial cells: 48.3;Neuronal cells: 44.5;Renal nephron cells: 40.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Spleen - Endothelial cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 5206 "cerebral cortex: 520593.2" "HPA024541, HPA052061" Uncertain Approved Nucleoplasm NA NA "Cluster 32: Basophils - Transcription" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 102: Non-specific - Mixed function" Nucleoplasm "HPA024541: , HPA052061: " "unprognostic (1.11e-3)" "unprognostic (1.85e-1)" "unprognostic (8.85e-2)" "unprognostic (4.98e-2)" "unprognostic (2.54e-1)" "unprognostic (1.56e-1)" "unprognostic (2.24e-1)" "unprognostic (1.42e-2)" "unprognostic (3.73e-3)" "unprognostic (1.13e-1)" "validated prognostic favorable (6.11e-6)" "validated prognostic favorable (8.54e-5)" "unprognostic (3.07e-2)" "unprognostic (1.41e-1)" "unprognostic (1.52e-1)" "unprognostic (6.84e-2)" "unprognostic (2.37e-1)" "unprognostic (1.93e-1)" "unprognostic (3.81e-2)" "unprognostic (6.00e-2)" "unprognostic (1.95e-2)" "unprognostic (4.54e-2)" "unprognostic (4.01e-1)" "unprognostic (1.34e-1)" "unprognostic (2.00e-1)" "unprognostic (1.76e-1)" "potential prognostic unfavorable (2.90e-4)" "unprognostic (1.60e-2)" "unprognostic (1.49e-1)" "unprognostic (3.78e-2)" "unprognostic (2.24e-1)" ZNF573 FLJ30921 ENSG00000189144 "Zinc finger protein 573" Q86YE8 19 37735833-37817300 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 221.4;Late spermatids: 452.4;Somatotrophs: 107.9" "Cell type enriched" "Detected in many" 4 "Spermatogenic cell types: 452.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 2149 "ovary: 214881.4" HPA042776 Uncertain Approved "Intermediate filaments,Cytosol" NA NA "Cluster 24: Non-specific - Transcription" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 23: Elongating spermatids - Sperm cell metabolism & fertilization" 1 "Intermediate filaments" Cytosol "HPA042776: " "unprognostic (7.26e-3)" "unprognostic (8.14e-2)" "unprognostic (6.68e-2)" "unprognostic (9.40e-2)" "unprognostic (2.50e-1)" "unprognostic (2.15e-3)" "unprognostic (1.92e-1)" "unprognostic (1.26e-1)" "unprognostic (2.00e-3)" "unprognostic (3.00e-2)" "unprognostic (3.22e-2)" "unprognostic (2.64e-1)" "unprognostic (3.10e-1)" ZNF574 FLJ22059 ENSG00000105732 "Zinc finger protein 574" Q6ZN55 19 42068477-42081552 "Essential proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early primary spermatocytes: 133.2;Late primary spermatocytes: 49.6" "Cell type enriched" "Detected in many" 5 "Spermatogenic cell types: 133.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 878313.1;Keratinocytes: 2357797.4" "Tissue enriched" "Detected in single" 21472 "lymphoid tissue: 2147158.8" "HPA023196, HPA057274" Approved Approved Nucleoplasm,Vesicles NA NA "Cluster 22: Eosinophils - Transcription" "Cluster 67: Testis - Mixed function" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 3: Early primary spermatocytes - Early meiosis" 3 Nucleoplasm Vesicles "HPA023196: , HPA057274: " "unprognostic (3.98e-3)" "unprognostic (1.03e-1)" "unprognostic (3.65e-1)" "unprognostic (3.36e-3)" "unprognostic (9.87e-2)" "unprognostic (9.90e-2)" "unprognostic (2.09e-1)" "unprognostic (8.97e-2)" "unprognostic (7.31e-2)" "unprognostic (3.01e-1)" "unprognostic (2.42e-3)" "unprognostic (2.77e-2)" "unprognostic (1.53e-1)" "unprognostic (5.60e-2)" "unprognostic (1.94e-2)" "unprognostic (1.99e-3)" "unprognostic (6.15e-2)" "unprognostic (1.04e-2)" "unprognostic (1.45e-1)" "unprognostic (3.65e-3)" "unprognostic (1.48e-1)" "unprognostic (9.89e-2)" "unprognostic (6.72e-2)" "unprognostic (2.06e-1)" "unprognostic (3.52e-2)" "unprognostic (2.54e-1)" "unprognostic (7.49e-2)" "unprognostic (3.79e-1)" "unprognostic (1.72e-1)" "unprognostic (7.51e-2)" "unprognostic (8.36e-2)" ZNF582 FLJ30927 ENSG00000018869 "Zinc finger protein 582" Q96NG8 19 56375846-56393538 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 31.5;Epicardial cells: 31.8" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 31.8;Myocytes: 31.5" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA028858 Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 22: Eosinophils - Transcription" "Cluster 65: Brain - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 1 Cytosol Nucleoplasm "HPA028858: " "unprognostic (6.09e-2)" "unprognostic (3.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.75e-2)" "unprognostic (1.99e-2)" "unprognostic (3.71e-2)" "unprognostic (1.36e-1)" "validated prognostic favorable (7.91e-6)" "validated prognostic favorable (3.30e-4)" "unprognostic (1.55e-2)" "unprognostic (2.28e-3)" "unprognostic (3.13e-2)" "unprognostic (4.84e-2)" "unprognostic (3.81e-2)" "unprognostic (5.20e-2)" "unprognostic (3.38e-2)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "potential prognostic favorable (9.87e-5)" "unprognostic (4.09e-2)" "unprognostic (2.85e-2)" "unprognostic (1.02e-1)" "unprognostic (7.25e-3)" "unprognostic (4.05e-2)" "unprognostic (1.47e-1)" "unprognostic (1.32e-1)" ZNF587B ENSG00000269343 "Zinc finger protein 587B" E7ETH6 19 57819721-57846238 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Late primary spermatocytes: 1.5;Medullary thymic epithelial cells: 4.8;Sertoli cells: 1.1" "Cell type enhanced" "Detected in some" "Secretory gland support: 4.8;Spermatogenic cell types: 1.5" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Prostate - Prostate basal glandular cells" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 387 "bone marrow: 38737.7" "HPA043800, HPA053762, HPA072145" Uncertain Uncertain Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 49: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (1.90e-1)" "unprognostic (5.29e-2)" "unprognostic (6.87e-3)" "unprognostic (3.77e-1)" "unprognostic (4.15e-1)" "unprognostic (1.08e-1)" "unprognostic (7.03e-2)" "unprognostic (2.28e-2)" "unprognostic (6.22e-2)" "potential prognostic favorable (7.46e-5)" "unprognostic (7.85e-3)" "unprognostic (1.57e-1)" "unprognostic (3.83e-3)" "unprognostic (4.62e-2)" "unprognostic (6.85e-3)" "unprognostic (5.58e-2)" "unprognostic (1.87e-1)" "unprognostic (1.69e-1)" "unprognostic (1.26e-1)" "unprognostic (3.95e-2)" "unprognostic (9.38e-3)" "potential prognostic unfavorable (6.50e-4)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "potential prognostic unfavorable (1.12e-6)" "unprognostic (8.34e-2)" "unprognostic (1.87e-1)" "unprognostic (1.42e-1)" "unprognostic (4.34e-2)" ZNF608 "DKFZp434M098, KIAA1281, NY-REN-36" ENSG00000168916 "Zinc finger protein 608" Q9ULD9 5 124636913-124748807 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 475.8;Oligodendrocyte progenitor cells: 298.4;Oligodendrocytes: 295.1;Pituitary stem cells: 363.7;Tuft cells: 357.4" "Cell type enhanced" "Detected in many" "Neutrophils: 475.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.5;naive B-cell: 1.5" "Group enriched" "Detected in many" 4 "B-cells: 1.5;granulocytes: 2.5" "Low cancer specificity" "Detected in many" "Pituitary gland - Undifferentiated cells (Pituitary gland), Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "Fallopian tube cells: 356310.3" "Not detected" "Not detected" "HPA005545, HPA076984" Approved Approved Nucleoplasm,Mitochondria NA NA "Cluster 32: Basophils - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 11: White matter - Signal transduction" "Cluster 6: Leukemia - Signal transduction" "Cluster 24: Neutrophils - Innate immunity signal integration" 8 Nucleoplasm Mitochondria "HPA005545: , HPA076984: " "unprognostic (1.70e-3)" "unprognostic (1.82e-1)" "unprognostic (7.99e-2)" "unprognostic (1.66e-1)" "unprognostic (6.98e-2)" "unprognostic (2.20e-1)" "unprognostic (5.26e-1)" "unprognostic (1.08e-1)" "unprognostic (1.23e-1)" "unprognostic (8.86e-2)" "unprognostic (2.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.76e-2)" "unprognostic (1.68e-1)" "unprognostic (3.58e-2)" "unprognostic (1.21e-1)" "unprognostic (1.23e-1)" "unprognostic (4.10e-2)" "unprognostic (6.86e-2)" "unprognostic (6.06e-3)" "unprognostic (1.33e-2)" "unprognostic (2.35e-1)" "unprognostic (4.41e-2)" "unprognostic (4.44e-2)" "unprognostic (5.67e-2)" "unprognostic (1.22e-1)" "unprognostic (1.86e-1)" "unprognostic (2.61e-2)" "unprognostic (1.55e-1)" "unprognostic (5.90e-2)" "unprognostic (6.92e-2)" ZNF614 FLJ21941 ENSG00000142556 "Zinc finger protein 614" Q8N883 19 52012765-52030240 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 37.5;Early spermatids: 72.7;Late spermatids: 49.7" "Cell type enhanced" "Detected in many" "Myocytes: 37.5;Spermatogenic cell types: 72.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 2319 "Fallopian tube cells: 222129.8;Neurons: 241754.1" "Not detected" "Not detected" HPA021197 Uncertain Approved Nucleoplasm,Vesicles,Cytosol No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 40: Non-specific - Mixed function" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 42: Early spermatids - Spermiogenesis: Acrosomal phase" 3 Nucleoplasm "Vesicles, Cytosol" "HPA021197: " "unprognostic (2.49e-2)" "unprognostic (9.69e-2)" "unprognostic (1.31e-1)" "unprognostic (4.32e-3)" "unprognostic (2.48e-2)" "unprognostic (3.01e-1)" "unprognostic (2.05e-2)" "unprognostic (2.55e-1)" "unprognostic (5.62e-1)" "unprognostic (8.77e-2)" "validated prognostic favorable (7.07e-6)" "validated prognostic favorable (7.38e-4)" "unprognostic (2.17e-1)" "unprognostic (1.87e-2)" "unprognostic (1.59e-1)" "unprognostic (1.95e-1)" "unprognostic (2.90e-1)" "potential prognostic favorable (3.52e-6)" "unprognostic (4.85e-1)" "unprognostic (3.73e-1)" "unprognostic (8.92e-2)" "unprognostic (5.46e-2)" "unprognostic (1.22e-1)" "unprognostic (2.65e-2)" "unprognostic (1.30e-2)" "unprognostic (2.01e-1)" "unprognostic (3.04e-2)" "unprognostic (6.29e-3)" "unprognostic (2.32e-1)" "unprognostic (7.03e-2)" "unprognostic (2.44e-1)" ZNF625 ENSG00000257591 "Zinc finger protein 625" Q96I27 19 12142090-12156734 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 8.2" "Group enriched" "Detected in some" 6 "Astrocytes: 10.1;Bergmann glia: 14.7;Brain excitatory neurons: 12.6;Brain inhibitory neurons: 10.4;Choroid plexus epithelial cells: 11.7;Ependymal cells: 11.4;Microglia: 8.5;Oligodendrocyte progenitor cells: 14.4;Oligodendrocytes: 8.8;Other brain neurons: 14.2" "Group enriched" "Detected in some" 6 "Ciliated cells: 11.7;Glial cells: 14.7;Neuronal cells: 14.2" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 17.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Cell type enriched" "Detected in single" 665 "Granulosa cells: 66536.6" "Not detected" "Not detected" HPA074014 Approved Nucleoplasm,Mitochondria NA NA "Cluster 24: Non-specific - Transcription" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 22: Non-specific - Basic cellular functions" 4 Mitochondria Nucleoplasm "HPA074014: " "unprognostic (2.63e-2)" "unprognostic (6.94e-2)" "unprognostic (3.04e-2)" "unprognostic (1.48e-2)" "unprognostic (1.01e-1)" "unprognostic (4.33e-2)" "unprognostic (9.72e-3)" "unprognostic (3.09e-3)" "unprognostic (1.75e-1)" "unprognostic (3.12e-1)" "unprognostic (1.33e-2)" "unprognostic (3.50e-3)" "unprognostic (5.97e-3)" "unprognostic (5.72e-2)" "unprognostic (5.89e-2)" "unprognostic (7.74e-2)" "unprognostic (2.09e-1)" "unprognostic (1.80e-1)" "unprognostic (3.95e-3)" "unprognostic (2.00e-1)" "unprognostic (1.49e-1)" "unprognostic (1.31e-1)" "unprognostic (2.42e-2)" "unprognostic (2.20e-2)" "unprognostic (1.20e-1)" "unprognostic (7.16e-2)" "unprognostic (2.62e-1)" ZNF627 FLJ90365 ENSG00000198551 "Zinc finger protein 627" Q7L945 19 11559374-11619161 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatocytes" "Not detected" "Not detected" "Cell type enriched" "Detected in single" 115 "Granulosa cells: 11471.2" "Not detected" "Not detected" "HPA049770, HPA073463" Uncertain Approved Nucleoplasm,Nucleoli NA NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 55: Non-specific - Transcription" "Cluster 23: Non-specific - Transcription" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 9 Nucleoplasm Nucleoli "HPA049770: , HPA073463: " "unprognostic (2.61e-3)" "unprognostic (8.97e-2)" "potential prognostic unfavorable (7.30e-4)" "unprognostic (2.39e-1)" "unprognostic (1.30e-1)" "unprognostic (1.99e-1)" "unprognostic (1.12e-2)" "unprognostic (6.30e-2)" "unprognostic (3.76e-3)" "unprognostic (4.62e-2)" "potential prognostic favorable (1.41e-8)" "unprognostic (3.67e-3)" "unprognostic (5.11e-2)" "unprognostic (2.68e-1)" "unprognostic (5.96e-2)" "unprognostic (7.63e-2)" "unprognostic (1.09e-2)" "unprognostic (3.28e-1)" "unprognostic (3.39e-2)" "unprognostic (6.83e-2)" "unprognostic (6.27e-2)" "unprognostic (1.78e-1)" "unprognostic (3.11e-1)" "unprognostic (2.09e-2)" "unprognostic (6.65e-3)" "unprognostic (2.16e-1)" "unprognostic (8.14e-3)" "unprognostic (3.77e-1)" "unprognostic (1.28e-2)" "unprognostic (1.11e-1)" "unprognostic (6.93e-2)" ZNF652 KIAA0924 ENSG00000198740 "Zinc finger protein 652" Q9Y2D9 17 49289206-49362473 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Macrophages: 327626.2;T-cells: 762005.2" "Tissue enriched" "Detected in single" 1283 "lymphoid tissue: 128329.0" HPA044408 Uncertain Approved Nucleoplasm No No "Cluster 35: Neutrophils - Protein binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 11: White matter - Signal transduction" "Cluster 27: Breast cancer - Unknown function" "Cluster 7: Non-specific - Transcription" 1 Nucleoplasm "HPA044408: " "unprognostic (3.92e-2)" "unprognostic (1.18e-1)" "unprognostic (3.13e-1)" "unprognostic (8.53e-2)" "unprognostic (2.72e-2)" "unprognostic (2.69e-2)" "unprognostic (1.48e-1)" "unprognostic (1.15e-1)" "unprognostic (6.17e-2)" "unprognostic (3.13e-1)" "potential prognostic favorable (1.05e-4)" "unprognostic (1.19e-3)" "unprognostic (1.78e-1)" "unprognostic (3.09e-1)" "unprognostic (1.60e-1)" "unprognostic (1.29e-1)" "unprognostic (2.21e-1)" "unprognostic (2.27e-1)" "unprognostic (6.27e-3)" "unprognostic (3.33e-3)" "unprognostic (3.70e-1)" "unprognostic (1.18e-2)" "unprognostic (2.01e-1)" "unprognostic (1.19e-1)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (2.06e-1)" "unprognostic (7.12e-2)" "unprognostic (8.39e-2)" "unprognostic (1.16e-2)" "unprognostic (4.63e-2)" ZNF654 "FLJ10997, FLJ21142" ENSG00000175105 "Zinc finger protein 654" Q8IZM8 3 88059255-88144660 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 9.7" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in some" "T-cells: 1500661.0" "Tissue enriched" "Detected in single" 248 "lymphoid tissue: 24836.8" "HPA036172, HPA036173, HPA049262, HPA077939" Uncertain Approved "Nucleoplasm,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 5: Non-specific - Cell proliferation" "Cluster 32: Retina & Lymphoid tissues - Signaling" "Cluster 55: Non-specific - Transcription" "Cluster 13: Non-specific - Mixed function" "Cluster 7: Non-specific - Transcription" Microtubules "Nucleoplasm, Cytokinetic bridge, Mitotic spindle" "HPA036172: , HPA036173: , HPA049262: , HPA077939: " "unprognostic (3.57e-2)" "unprognostic (3.18e-2)" "unprognostic (1.05e-1)" "unprognostic (1.69e-2)" "unprognostic (2.91e-1)" "unprognostic (3.78e-3)" "unprognostic (3.51e-1)" "unprognostic (3.92e-1)" "unprognostic (2.44e-2)" "unprognostic (2.83e-3)" "potential prognostic favorable (1.70e-6)" "unprognostic (6.49e-3)" "unprognostic (3.53e-2)" "unprognostic (8.24e-2)" "unprognostic (1.96e-1)" "unprognostic (1.80e-2)" "unprognostic (1.13e-1)" "unprognostic (3.01e-2)" "unprognostic (2.18e-1)" "unprognostic (1.42e-1)" "unprognostic (6.61e-2)" "unprognostic (7.42e-3)" "unprognostic (2.67e-2)" "unprognostic (3.10e-3)" "unprognostic (3.92e-3)" "unprognostic (3.59e-1)" "unprognostic (2.44e-1)" "unprognostic (2.56e-1)" "unprognostic (1.59e-1)" "unprognostic (4.66e-2)" "unprognostic (2.90e-1)" ZNF658 "DKFZp572C163, FLJ32813, MGC35232" ENSG00000274349 "Zinc finger protein 658" Q5TYW1 9 66856426-66932141 "Predicted intracellular proteins, Transcription factors" "Ribosome biogenesis, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.3;Distal convoluted tubule cells: 19.9" "Cell type enhanced" "Detected in many" "Myocytes: 27.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 11 "neutrophil: 28.1" "Lineage enriched" "Detected in many" 11 "granulocytes: 28.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 116654 "Skeletal myofibers: 11665383.0" "Not detected" "Not detected" "HPA047730, HPA048668" Uncertain Approved Nucleoplasm No No "Cluster 21: Neutrophils - Unknown function" "Cluster 61: Non-specific - Transcription" "Cluster 31: Non-specific - Transcription" "Cluster 43: Non-specific - Basic cellular processes" "Cluster 55: Myocytes - Oxidative muscle function" 3 Nucleoplasm "HPA047730: , HPA048668: " "unprognostic (8.33e-3)" "unprognostic (1.00e-1)" "unprognostic (1.07e-1)" "unprognostic (9.33e-2)" "unprognostic (4.09e-2)" "unprognostic (1.29e-1)" "unprognostic (4.19e-3)" "unprognostic (1.55e-2)" "unprognostic (6.59e-2)" "potential prognostic favorable (4.69e-4)" "unprognostic (2.35e-3)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" "unprognostic (1.52e-2)" "unprognostic (6.86e-2)" "unprognostic (4.16e-1)" "unprognostic (4.47e-2)" "unprognostic (1.54e-1)" "potential prognostic favorable (4.16e-4)" "unprognostic (7.50e-2)" "unprognostic (1.08e-3)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.08e-3)" "unprognostic (7.83e-2)" "unprognostic (8.77e-3)" "unprognostic (2.86e-1)" ZNF672 FLJ22301 ENSG00000171161 "Zinc finger protein 672" Q499Z4 1 248838210-248849517 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 93.4" "Cell type enhanced" "Detected in all" "Trophoblast cells: 93.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting ducts: 443919.9;Granulosa cells: 389836.7;Large ducts: 413176.0" "Tissue enriched" "Detected in single" 4066 "lymphoid tissue: 406573.2" "HPA055779, HPA062506" Approved Enhanced Nucleoplasm Yes Yes "Cluster 2: Dendritic cells - Unknown function" "Cluster 24: Non-specific - Transcription" "Cluster 25: Non-specific - Transcription" "Cluster 45: Non-specific - Nuclear processes" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 5 Nucleoplasm "HPA055779: , HPA062506: " "unprognostic (5.55e-3)" "unprognostic (1.22e-3)" "unprognostic (1.78e-1)" "unprognostic (1.43e-1)" "unprognostic (6.40e-2)" "unprognostic (5.16e-3)" "unprognostic (2.70e-1)" "unprognostic (5.13e-3)" "unprognostic (3.18e-3)" "unprognostic (1.35e-1)" "potential prognostic favorable (6.50e-4)" "unprognostic (1.12e-1)" "unprognostic (7.13e-2)" "unprognostic (1.36e-2)" "unprognostic (1.86e-3)" "unprognostic (3.96e-2)" "unprognostic (3.04e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (4.26e-2)" "unprognostic (5.05e-3)" "potential prognostic favorable (3.37e-4)" "unprognostic (9.67e-2)" "unprognostic (4.19e-2)" "unprognostic (4.93e-2)" "unprognostic (2.05e-2)" "unprognostic (3.84e-1)" "unprognostic (6.96e-2)" "unprognostic (8.77e-2)" "potential prognostic unfavorable (1.38e-4)" "unprognostic (8.54e-2)" ZNF678 MGC42493 ENSG00000181450 "Zinc finger protein 678" Q5SXM1 1 227563543-227677443 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 66 "salivary gland: 6614.2" HPA028507 Uncertain Approved Nucleoplasm,Nucleoli,Cytosol Yes No "Cluster 5: Non-specific - Cell proliferation" "Cluster 61: Non-specific - Transcription" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 45: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" Nucleoli "Nucleoplasm, Cytosol" "HPA028507: " "unprognostic (4.06e-2)" "unprognostic (4.19e-2)" "unprognostic (2.81e-1)" "unprognostic (1.54e-2)" "unprognostic (8.65e-2)" "unprognostic (2.31e-1)" "unprognostic (3.48e-2)" "unprognostic (5.47e-3)" "unprognostic (3.07e-3)" "unprognostic (1.27e-3)" "unprognostic (8.41e-3)" "unprognostic (3.78e-1)" "unprognostic (1.31e-1)" "unprognostic (3.13e-2)" "unprognostic (2.39e-2)" "unprognostic (5.24e-3)" "unprognostic (3.77e-3)" "unprognostic (1.34e-1)" "unprognostic (2.11e-1)" "unprognostic (1.42e-1)" "unprognostic (8.50e-3)" "unprognostic (2.96e-1)" "unprognostic (2.78e-2)" "unprognostic (2.58e-1)" "unprognostic (3.11e-2)" "unprognostic (2.12e-2)" "unprognostic (3.30e-2)" "unprognostic (2.92e-2)" "unprognostic (3.03e-1)" "unprognostic (3.37e-2)" "unprognostic (1.56e-1)" ZNF687 KIAA1441 ENSG00000143373 "Zinc finger protein 687" Q8N1G0 1 151281618-151292176 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 28.8" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.5" "Group enriched" "Detected in many" 8 "granulocytes: 13.5;monocytes: 4.5" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 1950426.6;Neutrophils: 1571450.8" "Tissue enriched" "Detected in some" "lymphoid tissue: 2824895.7" "HPA021193, HPA023948" Approved Enhanced Nucleoplasm NA NA "Cluster 7: Non-specific - Innate immune response" "Cluster 24: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 45: Non-specific - Nuclear processes" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 26 Nucleoplasm "HPA021193: , HPA023948: " "unprognostic (1.39e-1)" "unprognostic (1.96e-1)" "unprognostic (8.84e-2)" "unprognostic (3.02e-1)" "unprognostic (1.11e-1)" "unprognostic (9.78e-2)" "unprognostic (1.44e-1)" "potential prognostic favorable (1.84e-4)" "unprognostic (2.00e-2)" "unprognostic (8.34e-2)" "potential prognostic favorable (7.92e-4)" "unprognostic (5.94e-2)" "unprognostic (1.13e-1)" "unprognostic (1.71e-2)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (2.92e-2)" "unprognostic (7.01e-2)" "unprognostic (1.24e-2)" "unprognostic (5.78e-2)" "unprognostic (8.07e-2)" "unprognostic (2.23e-2)" "unprognostic (1.02e-1)" "unprognostic (4.51e-2)" "unprognostic (5.90e-2)" "unprognostic (2.35e-1)" "unprognostic (4.25e-1)" "unprognostic (3.02e-1)" "unprognostic (2.19e-1)" "unprognostic (1.24e-1)" "unprognostic (2.98e-1)" ZNF689 "FLJ90415, TIPUH1" ENSG00000156853 "Zinc finger protein 689" Q96CS4 16 30602558-30624012 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 18.2" "Cell type enhanced" "Detected in many" "Breast hormone-responsive cells: 55.2;Early spermatids: 44.6;Late primary spermatocytes: 151.7;Late spermatids: 83.1;Oocytes: 46.1" "Cell type enhanced" "Detected in many" "Luminal cells: 55.2;Spermatogenic cell types: 151.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Adrenal gland - Adrenal cortex cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 1960 "Granulosa cells: 79180.7;Oocytes: 312766.7" "Not detected" "Not detected" "HPA054095, HPA055385" Approved Approved "Nucleoplasm,Nucleoli fibrillar center" No No "Cluster 33: Non-specific - ATP binding" "Cluster 39: Testis - Nuclear processes" "Cluster 40: Astrocytes - Astrocyte-neuron interactions" "Cluster 54: Non-specific - Transcription" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 8 "Nucleoplasm, Nucleoli fibrillar center" "HPA054095: , HPA055385: " "unprognostic (1.04e-1)" "unprognostic (1.68e-1)" "unprognostic (2.95e-2)" "unprognostic (1.53e-1)" "unprognostic (4.80e-2)" "unprognostic (9.34e-2)" "unprognostic (3.25e-1)" "unprognostic (2.13e-3)" "unprognostic (1.20e-1)" "unprognostic (5.96e-2)" "potential prognostic favorable (5.49e-5)" "unprognostic (5.49e-2)" "unprognostic (2.21e-1)" "unprognostic (7.89e-2)" "unprognostic (1.12e-1)" "unprognostic (8.03e-2)" "unprognostic (1.59e-1)" "unprognostic (2.53e-1)" "unprognostic (1.03e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (3.44e-3)" "unprognostic (6.15e-2)" "unprognostic (3.02e-1)" "unprognostic (2.12e-2)" "unprognostic (3.25e-2)" "unprognostic (8.94e-3)" "unprognostic (2.22e-1)" "unprognostic (1.57e-1)" "unprognostic (1.32e-1)" "unprognostic (3.74e-1)" ZNF692 "AREBP, FLJ20531, Zfp692" ENSG00000171163 "Zinc finger protein 692" Q9BU19 1 248850006-248859144 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late primary spermatocytes: 76.3" "Cell type enhanced" "Detected in many" "Spermatogenic cell types: 76.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA059337, HPA062792" Uncertain Enhanced Nucleoplasm,Nucleoli NA NA "Cluster 14: Non-specific - Unknown function" "Cluster 64: Non-specific - Transcription" "Cluster 6: Non-specific - Immune response" "Cluster 35: RS4;11 - Unknown function" "Cluster 53: Late primary spermatocytes - Meiotic division & transition" 4 "Nucleoplasm, Nucleoli" "HPA059337: , HPA062792: " "unprognostic (2.10e-1)" "unprognostic (3.04e-1)" "unprognostic (6.04e-2)" "unprognostic (1.98e-1)" "unprognostic (2.75e-2)" "potential prognostic unfavorable (4.15e-5)" "unprognostic (3.36e-1)" "unprognostic (3.15e-3)" "unprognostic (1.43e-1)" "unprognostic (1.86e-2)" "potential prognostic unfavorable (2.68e-5)" "unprognostic (5.60e-2)" "unprognostic (1.97e-2)" "potential prognostic unfavorable (7.18e-4)" "unprognostic (1.69e-1)" "unprognostic (9.88e-2)" "potential prognostic unfavorable (9.88e-5)" "unprognostic (1.71e-2)" "unprognostic (2.65e-2)" "unprognostic (1.68e-1)" "unprognostic (1.93e-2)" "unprognostic (2.32e-3)" "unprognostic (2.05e-2)" "unprognostic (3.69e-2)" "unprognostic (3.68e-1)" "unprognostic (1.40e-1)" "unprognostic (6.92e-2)" "unprognostic (1.46e-2)" "unprognostic (3.94e-2)" "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" ZNF696 FLJ14129 ENSG00000185730 "Zinc finger protein 696" Q9H7X3 8 143289676-143299952 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 15.0" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA057855, HPA072473" Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 30: Non-specific - DNA binding" "Cluster 64: Non-specific - Transcription" "Cluster 48: Non-specific - Mixed function" "Cluster 40: Non-specific - Unknown function" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" 38 Nucleoplasm Nucleoli "HPA057855: , HPA072473: " "unprognostic (6.82e-2)" "unprognostic (2.55e-2)" "unprognostic (1.87e-1)" "potential prognostic unfavorable (1.58e-4)" "unprognostic (4.06e-2)" "unprognostic (1.50e-1)" "unprognostic (3.71e-1)" "unprognostic (2.71e-3)" "unprognostic (1.29e-1)" "unprognostic (2.53e-3)" "unprognostic (1.00e-1)" "unprognostic (4.05e-2)" "unprognostic (1.60e-1)" "unprognostic (4.35e-3)" "unprognostic (5.49e-2)" "unprognostic (4.71e-1)" "unprognostic (1.63e-2)" "unprognostic (2.55e-1)" "unprognostic (4.72e-3)" "unprognostic (3.12e-1)" "unprognostic (1.44e-1)" "unprognostic (3.97e-3)" "unprognostic (2.78e-2)" "unprognostic (1.40e-1)" "unprognostic (3.13e-1)" "unprognostic (2.48e-1)" "unprognostic (1.43e-1)" "unprognostic (2.46e-1)" "unprognostic (3.68e-1)" "unprognostic (1.86e-2)" "unprognostic (1.36e-1)" ZNF70 "Cos17, MGC48959" ENSG00000187792 "Zinc finger protein 70" Q9UC06 22 23738682-23751112 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 25.8;Myosatellite cells: 15.8;Retinal horizontal cells: 16.0;Thymic myoid cells: 15.0" "Cell type enhanced" "Detected in many" "Stellate cells: 25.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in many" "Prostate - Fibroblasts" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 616 "Granulosa cells: 61573.7" "Not detected" "Not detected" HPA018821 Uncertain Approved Cytosol NA NA "Cluster 20: Non-specific - DNA binding" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 6: Leukemia - Signal transduction" "Cluster 37: Neutrophil progenitors - Granulopoiesis" 2 Cytosol "HPA018821: " "unprognostic (2.81e-3)" "unprognostic (1.33e-2)" "unprognostic (2.58e-1)" "unprognostic (1.03e-2)" "unprognostic (1.12e-1)" "unprognostic (1.58e-1)" "unprognostic (4.94e-2)" "unprognostic (2.24e-1)" "unprognostic (2.98e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (1.22e-2)" "unprognostic (1.61e-1)" "unprognostic (3.99e-2)" "unprognostic (1.20e-1)" "unprognostic (1.30e-2)" "unprognostic (3.23e-3)" "unprognostic (1.35e-1)" "unprognostic (1.37e-1)" "unprognostic (1.53e-2)" "unprognostic (4.41e-2)" "unprognostic (2.50e-2)" "unprognostic (4.54e-2)" "unprognostic (1.06e-1)" "unprognostic (2.05e-2)" "unprognostic (1.17e-1)" "unprognostic (1.78e-1)" "unprognostic (2.29e-1)" ZNF711 "CMPX1, dJ75N13.1, MRX65, MRX97, Zfp711, ZNF4, ZNF5, ZNF6" ENSG00000147180 "Zinc finger protein 711" Q9Y462 X 85243991-85273362 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 34.9" "Cell type enriched" "Detected in many" 5 "Sertoli cells: 451.8" "Cell type enriched" "Detected in many" 5 "Reproductive supporting cells: 451.8" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Glioblastoma Multiforme (TCGA): 13.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Lineage enhanced" "Detected in single" "B-cells: 1.3" "Cancer enhanced" "Detected in many" "Neuroblastoma: 31.8" "Adrenal gland - Adrenal cortex cells, Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 68 "cerebral cortex: 6793.4" HPA030654 Enhanced Approved Nucleoplasm NA NA "Cluster 75: Ovary - Mixed function" "Cluster 14: Neurons - Synaptic function" "Cluster 17: Neuroblastoma - Neuronal signaling" "Cluster 43: Sertoli cells - Spermatogenesis microenvironment" 6 Nucleoplasm "HPA030654: " "unprognostic (1.33e-2)" "unprognostic (1.01e-1)" "unprognostic (3.62e-1)" "unprognostic (2.81e-1)" "unprognostic (3.36e-1)" "unprognostic (1.34e-1)" "unprognostic (6.06e-2)" "potential prognostic favorable (3.09e-4)" "unprognostic (4.19e-2)" "unprognostic (1.38e-3)" "potential prognostic favorable (2.61e-4)" "unprognostic (2.77e-1)" "unprognostic (1.15e-2)" "unprognostic (4.97e-2)" "unprognostic (1.20e-1)" "unprognostic (1.68e-3)" "unprognostic (2.19e-2)" "unprognostic (7.12e-3)" "unprognostic (1.19e-1)" "unprognostic (3.48e-2)" "unprognostic (8.11e-3)" "unprognostic (5.48e-2)" "unprognostic (1.60e-1)" "unprognostic (9.11e-2)" "unprognostic (9.76e-2)" "unprognostic (1.39e-1)" "unprognostic (7.74e-2)" "unprognostic (1.08e-1)" ZNF766 ENSG00000196214 "Zinc finger protein 766" Q5HY98 19 52269587-52296046 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 89.5" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids, Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA044882, HPA063496" Uncertain Supported Centrosome NA NA "Cluster 3: Non-specific - Nuclear processes" "Cluster 39: Testis - Nuclear processes" "Cluster 6: Non-specific - Immune response" "Cluster 4: Non-specific - Transcription" "Cluster 7: Non-specific - Transcription" 5 Centrosome "HPA044882: , HPA063496: " "unprognostic (3.95e-3)" "unprognostic (1.01e-1)" "unprognostic (6.05e-2)" "unprognostic (6.62e-2)" "unprognostic (2.87e-1)" "unprognostic (2.66e-1)" "unprognostic (9.07e-2)" "unprognostic (2.93e-1)" "unprognostic (4.49e-3)" "unprognostic (3.21e-2)" "unprognostic (1.82e-3)" "unprognostic (8.29e-3)" "unprognostic (2.89e-1)" "unprognostic (5.87e-2)" "unprognostic (1.70e-1)" "unprognostic (1.33e-1)" "unprognostic (4.00e-2)" "unprognostic (8.51e-2)" "unprognostic (2.12e-1)" "unprognostic (7.24e-2)" "unprognostic (2.60e-1)" "unprognostic (1.41e-2)" "unprognostic (1.84e-1)" "unprognostic (1.73e-2)" "unprognostic (1.15e-3)" "unprognostic (2.58e-1)" "unprognostic (4.07e-2)" "unprognostic (2.10e-1)" "unprognostic (4.88e-2)" "unprognostic (1.55e-1)" "unprognostic (9.50e-2)" ZNF77 pT1 ENSG00000175691 "Zinc finger protein 77" Q15935 19 2933218-2944971 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA023397 Uncertain Approved Nucleoplasm,Nucleoli No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 64: Non-specific - Transcription" "Cluster 35: Non-specific - DNA binding" "Cluster 23: Non-specific - Transcription" "Cluster 39: Syncytiotrophoblasts - Placental homeostasis & endocrine signal" 10 "Nucleoplasm, Nucleoli" "HPA023397: " "unprognostic (5.33e-3)" "unprognostic (7.07e-2)" "unprognostic (2.69e-2)" "unprognostic (1.95e-1)" "unprognostic (2.01e-1)" "unprognostic (2.26e-1)" "unprognostic (5.47e-2)" "unprognostic (1.61e-2)" "unprognostic (1.05e-1)" "unprognostic (5.60e-2)" "unprognostic (5.59e-3)" "unprognostic (5.80e-2)" "unprognostic (8.97e-2)" "unprognostic (1.79e-2)" "unprognostic (1.38e-1)" "potential prognostic favorable (2.71e-4)" "unprognostic (2.22e-1)" "unprognostic (1.25e-2)" "potential prognostic favorable (1.98e-4)" "unprognostic (1.72e-1)" "unprognostic (1.88e-1)" "unprognostic (4.40e-3)" "unprognostic (4.56e-2)" "unprognostic (9.64e-3)" "unprognostic (1.83e-2)" "unprognostic (1.96e-2)" "unprognostic (4.07e-2)" "unprognostic (1.64e-1)" "unprognostic (9.50e-2)" "unprognostic (1.17e-1)" "unprognostic (7.19e-2)" ZNF771 DSC43 ENSG00000179965 "Zinc finger protein 771" Q7L3S4 16 30407414-30431108 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Sertoli cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030730, HPA046672, HPA059398" Uncertain Enhanced Nucleoplasm,Nucleoli No No "Cluster 43: Non-specific - Transcription & Translation" "Cluster 78: Brain - Neuronal signaling" "Cluster 32: Cerebral cortex - Mixed function" "Cluster 35: RS4;11 - Unknown function" "Cluster 94: Gonadal somatic cells - Mixed function" 13 "Nucleoplasm, Nucleoli" "HPA030730: , HPA046672: , HPA059398: " "unprognostic (2.19e-2)" "unprognostic (4.28e-2)" "unprognostic (9.51e-2)" "unprognostic (4.35e-2)" "unprognostic (8.08e-3)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "potential prognostic favorable (1.65e-5)" "unprognostic (1.32e-1)" "unprognostic (6.67e-2)" "unprognostic (1.51e-1)" "unprognostic (1.14e-1)" "unprognostic (2.43e-1)" "unprognostic (1.24e-1)" "unprognostic (2.69e-1)" "unprognostic (6.66e-2)" "unprognostic (8.49e-2)" "unprognostic (1.56e-2)" "potential prognostic favorable (5.62e-4)" "unprognostic (3.58e-2)" "unprognostic (8.31e-2)" "potential prognostic favorable (3.28e-4)" "unprognostic (7.26e-2)" "unprognostic (2.91e-2)" "potential prognostic favorable (4.06e-4)" "unprognostic (2.59e-1)" "unprognostic (2.47e-2)" "unprognostic (1.00e-1)" "unprognostic (7.23e-2)" "unprognostic (4.77e-2)" "unprognostic (1.11e-2)" ZNF774 MGC75360 ENSG00000196391 "Zinc finger protein 774" Q6NX45 15 90352284-90369146 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adrenal cortex cells: 23.3;Myonuclei: 42.3" "Cell type enhanced" "Detected in many" "Myocytes: 42.3" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Not detected" "Not detected" "Not detected" "Not detected" "HPA030839, HPA030840" Uncertain Supported "Intermediate filaments,Cytosol" No No "Cluster 20: Non-specific - DNA binding" "Cluster 25: Non-specific - Basic cellular processes" "Cluster 15: Non-specific - Transcription" "Cluster 57: Stomach & Colon cancer - Digestion" "Cluster 55: Myocytes - Oxidative muscle function" 68 "Intermediate filaments" Cytosol "HPA030839: , HPA030840: " "unprognostic (9.07e-3)" "unprognostic (1.33e-1)" "unprognostic (4.06e-1)" "unprognostic (3.18e-2)" "unprognostic (4.43e-1)" "unprognostic (3.76e-3)" "unprognostic (1.80e-1)" "unprognostic (2.68e-3)" "unprognostic (1.53e-1)" "potential prognostic unfavorable (2.11e-5)" "unprognostic (1.28e-1)" "potential prognostic favorable (9.58e-4)" "unprognostic (1.99e-1)" "unprognostic (4.02e-2)" "unprognostic (2.23e-1)" "unprognostic (3.01e-2)" "unprognostic (5.15e-3)" "unprognostic (2.09e-2)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (5.74e-1)" "unprognostic (1.27e-1)" "unprognostic (4.83e-3)" "unprognostic (2.11e-2)" "unprognostic (9.71e-3)" "unprognostic (2.01e-1)" "unprognostic (1.73e-1)" "unprognostic (4.09e-2)" ZNF776 FLJ38288 ENSG00000152443 "Zinc finger protein 776" Q68DI1 19 57746815-57758148 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046653, HPA068553" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 41: Basophils - Unknown function" "Cluster 22: Epididymis - Mixed function" "Cluster 31: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 5 Nucleoplasm Cytosol "HPA046653: , HPA068553: " "unprognostic (1.45e-3)" "unprognostic (4.53e-2)" "unprognostic (1.22e-1)" "unprognostic (7.49e-2)" "unprognostic (2.29e-1)" "unprognostic (2.20e-1)" "unprognostic (3.63e-1)" "unprognostic (1.19e-1)" "unprognostic (1.16e-1)" "unprognostic (2.81e-1)" "potential prognostic favorable (7.05e-7)" "unprognostic (2.84e-3)" "unprognostic (6.33e-2)" "unprognostic (9.46e-2)" "unprognostic (2.65e-2)" "unprognostic (5.15e-2)" "unprognostic (1.65e-1)" "unprognostic (1.04e-1)" "unprognostic (1.75e-1)" "unprognostic (7.82e-2)" "unprognostic (2.18e-1)" "unprognostic (4.08e-2)" "unprognostic (1.43e-1)" "unprognostic (1.83e-2)" "unprognostic (3.42e-2)" "unprognostic (2.42e-1)" "unprognostic (6.00e-2)" "unprognostic (1.77e-2)" "unprognostic (1.89e-1)" "unprognostic (8.28e-2)" "unprognostic (2.03e-1)" ZNF814 ENSG00000204514 "Zinc finger protein 814" B7Z6K7 19 57848731-57889074 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 211.3" "Cell type enhanced" "Detected in all" "Myocytes: 211.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043800, HPA053762, HPA072145" Approved Uncertain Nucleoplasm NA NA "Cluster 24: Non-specific - Transcription" "Cluster 64: Non-specific - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 4: Non-specific - Transcription" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" Nucleoplasm "HPA043800: , HPA053762: , HPA072145: " "unprognostic (8.46e-3)" "unprognostic (2.07e-1)" "unprognostic (7.74e-2)" "unprognostic (2.00e-1)" "unprognostic (3.73e-1)" "unprognostic (1.20e-1)" "unprognostic (1.94e-1)" "unprognostic (2.40e-1)" "unprognostic (1.63e-2)" "unprognostic (7.67e-2)" "validated prognostic favorable (3.43e-4)" "validated prognostic favorable (1.79e-4)" "potential prognostic favorable (7.67e-4)" "unprognostic (5.45e-2)" "unprognostic (1.01e-2)" "unprognostic (1.43e-1)" "unprognostic (6.67e-2)" "unprognostic (2.06e-1)" "unprognostic (2.68e-1)" "unprognostic (5.34e-3)" "unprognostic (1.16e-1)" "potential prognostic favorable (6.50e-4)" "unprognostic (5.52e-3)" "unprognostic (3.41e-3)" "unprognostic (3.08e-1)" "unprognostic (3.26e-2)" "potential prognostic unfavorable (5.86e-4)" "unprognostic (1.19e-1)" "unprognostic (1.68e-1)" "unprognostic (8.98e-2)" "unprognostic (1.89e-3)" ZNF829 DKFZp779O175 ENSG00000185869 "Zinc finger protein 829" Q3KNS6 19 36888124-36916291 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 6.2" "Cell type enriched" "Detected in many" 4 "Early spermatids: 335.9" "Cell type enriched" "Detected in many" 8 "Spermatogenic cell types: 335.9" "Low cell type specificity" "Detected in all" "Cancer enhanced" "Detected in many" "Testicular Germ Cell Tumor (TCGA): 6.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Testis - Early spermatids, Testis - Late spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA073073 Approved "Nucleoplasm,Nuclear bodies" No No "Cluster 5: Non-specific - Cell proliferation" "Cluster 57: Testis - Spermatogenesis" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 4: Non-specific - Transcription" "Cluster 33: Early spermatids - Spermiogenesis: Cap phase" 6 Nucleoplasm "Nuclear bodies" "HPA073073: " "unprognostic (2.72e-2)" "unprognostic (5.49e-2)" "unprognostic (1.31e-1)" "unprognostic (6.74e-3)" "potential prognostic favorable (6.29e-4)" "unprognostic (1.34e-1)" "unprognostic (1.11e-1)" "unprognostic (1.50e-2)" "validated prognostic favorable (6.80e-6)" "validated prognostic favorable (1.04e-4)" "unprognostic (2.31e-2)" "unprognostic (2.40e-1)" "unprognostic (2.75e-1)" "unprognostic (4.21e-1)" "unprognostic (3.11e-1)" "unprognostic (1.22e-1)" "unprognostic (2.25e-2)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "unprognostic (2.69e-3)" "unprognostic (3.41e-1)" "unprognostic (6.87e-2)" "unprognostic (1.72e-1)" ZNF835 BC37295_3 ENSG00000127903 "Zinc finger protein 835" Q9Y2P0 19 56661980-56671783 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 5.1;Oocytes: 9.2;Retinal ganglion cells: 7.7;Retinal horizontal cells: 6.0" "Cell type enhanced" "Detected in many" "Neuronal cells: 7.7;Oocytes: 9.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in some" "Heart muscle - Cardiomyocytes" "Not detected" "Not detected" "Not detected" "Not detected" HPA051136 Uncertain Approved "Microtubules,Cytokinetic bridge,Mitotic spindle,Primary cilium,Basal body" Yes NA "Cluster 24: Non-specific - Transcription" "Cluster 65: Brain - Transcription" "Cluster 37: Neurons - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 86: Retinal bipolar cells - Synaptic signal transduction" 54 Microtubules "Cytokinetic bridge, Mitotic spindle, Primary cilium, Basal body" "HPA051136: " "unprognostic (3.26e-1)" "unprognostic (1.54e-1)" "unprognostic (1.43e-1)" "unprognostic (8.94e-2)" "unprognostic (6.59e-2)" "validated prognostic favorable (7.30e-5)" "validated prognostic favorable (1.52e-4)" "unprognostic (5.88e-2)" "unprognostic (5.00e-2)" "unprognostic (2.31e-2)" "unprognostic (2.90e-2)" "unprognostic (7.94e-2)" "unprognostic (3.06e-1)" "unprognostic (2.19e-1)" "unprognostic (1.28e-1)" "unprognostic (3.86e-2)" ZNF843 MGC46336 ENSG00000176723 "Zinc finger protein 843" Q8N446 16 31432593-31443160 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 7.8;Myonuclei: 10.5" "Cell type enhanced" "Detected in many" "Myocytes: 10.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.7" "Low lineage specificity" "Detected in single" "Not detected" "Not detected" "Heart muscle - Cardiomyocytes" "Cell type enhanced" "Detected in many" "Smooth muscle cells: 1108986.0" "Not detected" "Not detected" "HPA030911, HPA030912, HPA077945" Uncertain Approved "Nucleoplasm,Nuclear speckles" NA NA "Cluster 65: Brain - Transcription" "Cluster 15: Non-specific - Transcription" "Cluster 27: Breast cancer - Unknown function" "Cluster 55: Myocytes - Oxidative muscle function" 6 Nucleoplasm "Nuclear speckles" "HPA030911: , HPA030912: , HPA077945: " "unprognostic (1.29e-1)" "unprognostic (2.31e-1)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "unprognostic (1.65e-1)" "unprognostic (8.33e-2)" "unprognostic (1.03e-1)" "unprognostic (4.08e-2)" "unprognostic (4.25e-2)" "unprognostic (8.32e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "potential prognostic unfavorable (2.18e-5)" "unprognostic (1.04e-1)" ZNF852 ENSG00000178917 "Zinc finger protein 852" Q6ZMS4 3 44494847-44510636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Astrocytes: 9.7;Bergmann glia: 14.5;Brain excitatory neurons: 12.8;Brain inhibitory neurons: 12.1;Choroid plexus epithelial cells: 14.1;Distal convoluted tubule cells: 10.3;Ependymal cells: 9.1;Loop of henle epithelial cells: 6.8;Microglia: 9.6;Oligodendrocyte progenitor cells: 14.9;Oligodendrocytes: 13.1;Other brain neurons: 11.4;Podocytes: 7.7;Proximal tubule cells: 8.3;Renal collecting duct intercalated cells: 7.9;Renal collecting duct principal cells: 6.5;Renal connecting tubule cells: 7.2" "Group enriched" "Detected in some" 6 "Ciliated cells: 14.1;Ductal cells: 7.9;Glial cells: 14.9;Neuronal cells: 12.8;Renal nephron cells: 10.3" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048312, HPA071850" Uncertain Approved Cytosol NA NA "Cluster 30: Non-specific - DNA binding" "Cluster 38: Non-specific - Basic cellular processes" "Cluster 10: Cerebellum - Nucleic acid binding" "Cluster 8: Non-specific - Basic cellular processes" "Cluster 98: Neurons - Neurotransmission & signaling" Cytosol "HPA048312: , HPA071850: " "unprognostic (1.13e-1)" "unprognostic (8.11e-2)" "unprognostic (1.50e-1)" "unprognostic (7.59e-2)" "unprognostic (1.43e-2)" "unprognostic (1.38e-3)" "unprognostic (4.57e-2)" "unprognostic (1.20e-1)" "unprognostic (5.79e-2)" "unprognostic (1.79e-1)" "unprognostic (2.23e-1)" "unprognostic (1.03e-1)" "unprognostic (9.08e-2)" "validated prognostic favorable (1.05e-5)" "validated prognostic favorable (8.99e-4)" "unprognostic (1.20e-1)" "unprognostic (4.16e-1)" "unprognostic (2.70e-2)" ZNF860 ENSG00000197385 "Zinc finger protein 860" A6NHJ4 3 31981750-31991723 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 3.9" "Cell type enhanced" "Detected in many" "B-cells: 30.9;Corticotrophs: 32.0;Esophageal apical cells: 22.5;Müller glia: 17.7;Pituitary stem cells: 27.7" "Cell type enhanced" "Detected in many" "B-cells: 30.9;Pituitary endocrine cells: 32.0;Stem cells: 27.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 49 "memory B-cell: 7.0;naive B-cell: 5.3" "Lineage enriched" "Detected in single" 56 "B-cells: 7.0" "Low cancer specificity" "Detected in many" "Testis - Sertoli cells" "Not detected" "Not detected" "Not detected" "Not detected" HPA063386 Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim" NA NA "Cluster 17: B-cells - Immunoglobulins" "Cluster 22: Epididymis - Mixed function" "Cluster 1: Neurons - Mixed function" "Cluster 34: Testis cancer - Unknown function" "Cluster 87: B-cells - Adaptive immunity: Humoral response" 2 "Nucleoli, Nucleoli rim" Nucleoplasm "HPA063386: " "unprognostic (5.02e-2)" "unprognostic (5.54e-2)" "unprognostic (9.04e-2)" "unprognostic (2.80e-2)" "unprognostic (7.27e-3)" "potential prognostic unfavorable (2.78e-4)" "potential prognostic favorable (3.33e-4)" "unprognostic (1.94e-1)" "unprognostic (1.77e-2)" "unprognostic (4.20e-2)" "unprognostic (5.17e-3)" "unprognostic (4.07e-2)" "unprognostic (6.07e-2)" "unprognostic (1.93e-1)" "unprognostic (6.04e-3)" "unprognostic (2.71e-2)" "unprognostic (6.08e-2)" "unprognostic (6.32e-2)" "unprognostic (1.76e-1)" "unprognostic (2.30e-1)" "unprognostic (4.26e-2)" ZNF875 HKR1 ENSG00000181666 "Zinc finger protein 875" P10072 19 37312837-37369365 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 130.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 321.7;Choroid plexus epithelial cells: 156.8;Cone photoreceptor cells: 217.4;Rod photoreceptor cells: 240.7" "Cell type enhanced" "Detected in all" "Myocytes: 321.7;Neuronal cells: 240.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Colon - Enteric glia cells, Prostate - Prostate glandular cells, Testis - Sertoli cells" "Not detected" "Not detected" "Tissue enriched" "Detected in single" 8652 "intestine: 865169.8" "HPA036126, HPA044855" Approved Approved Nucleoplasm,Mitochondria No No "Cluster 14: Non-specific - Unknown function" "Cluster 46: Brain & retina - Neuronal signaling" "Cluster 48: Non-specific - Mixed function" "Cluster 4: Non-specific - Transcription" "Cluster 60: Cardiomyocytes - Cardiac muscle contraction & structure" "Nucleoplasm, Mitochondria" "HPA036126: , HPA044855: " "unprognostic (1.92e-2)" "unprognostic (1.04e-1)" "unprognostic (2.40e-2)" "unprognostic (2.27e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (3.01e-1)" "unprognostic (3.68e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (3.37e-3)" "potential prognostic favorable (8.48e-5)" "unprognostic (1.83e-1)" "unprognostic (9.85e-2)" "unprognostic (5.46e-2)" "unprognostic (8.32e-2)" "unprognostic (4.03e-2)" "unprognostic (3.23e-2)" "unprognostic (2.82e-1)" "unprognostic (6.16e-3)" "unprognostic (3.61e-2)" "unprognostic (1.09e-2)" "unprognostic (3.70e-2)" "unprognostic (2.37e-3)" "potential prognostic unfavorable (3.08e-4)" "unprognostic (5.78e-2)" "unprognostic (2.66e-1)" "unprognostic (6.32e-2)" "unprognostic (3.61e-2)" ZNFX1 "FLJ11277, KIAA1404" ENSG00000124201 "Zinc finger NFX1-type containing 1" Q9P2E3 20 49237946-49278426 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Immunity, Innate immunity" RNA-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 311.2" "Cell type enhanced" "Detected in all" "Neutrophils: 311.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Tissue enriched" "Detected in some" 1 "cerebral cortex: 2887546.1" HPA046629 Approved Approved Mitochondria No No "Cluster 35: Neutrophils - Protein binding" "Cluster 14: Adipose tissue - Angiogenesis" "Cluster 43: Hindbrain - Mixed function" "Cluster 31: Non-specific - Antiviral immune response" "Cluster 29: Neutrophils - Innate immune cellular maintenance" 18 Mitochondria "HPA046629: " "unprognostic (1.87e-3)" "unprognostic (8.06e-2)" "unprognostic (3.18e-2)" "unprognostic (3.65e-2)" "unprognostic (2.49e-1)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (1.52e-1)" "unprognostic (3.59e-1)" "unprognostic (9.54e-3)" "potential prognostic favorable (1.50e-4)" "unprognostic (4.02e-3)" "unprognostic (1.89e-1)" "unprognostic (3.93e-2)" "potential prognostic favorable (3.12e-4)" "unprognostic (2.97e-1)" "unprognostic (2.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.48e-1)" "unprognostic (6.56e-2)" "unprognostic (5.68e-3)" "unprognostic (1.11e-2)" "unprognostic (5.03e-2)" "unprognostic (2.84e-1)" "unprognostic (1.71e-2)" "unprognostic (1.07e-2)" "unprognostic (4.12e-1)" "unprognostic (1.85e-1)" "unprognostic (1.17e-1)" "unprognostic (1.18e-1)" "unprognostic (4.94e-3)" ZNHIT6 "BCD1, C1orf181, FLJ20729, NY-BR-75" ENSG00000117174 "Zinc finger HIT-type containing 6" Q9NWK9 1 85649417-85708433 "Essential proteins, Predicted intracellular proteins" "Ribosome biogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Granulosa cells: 136594.9;Large ducts: 91130.1" "Tissue enriched" "Detected in single" 10983 "ovary: 1098340.8" "HPA018132, HPA050253" Approved Approved "Nuclear speckles,Vesicles" No No "Cluster 24: Non-specific - Transcription" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 20 "Nuclear speckles, Vesicles" "HPA018132: , HPA050253: " "unprognostic (5.20e-2)" "unprognostic (2.47e-1)" "unprognostic (3.52e-1)" "unprognostic (6.38e-2)" "unprognostic (1.89e-1)" "unprognostic (2.76e-3)" "unprognostic (4.60e-3)" "unprognostic (2.40e-1)" "unprognostic (1.58e-1)" "potential prognostic unfavorable (9.49e-5)" "unprognostic (1.72e-3)" "potential prognostic favorable (3.37e-4)" "unprognostic (5.59e-3)" "potential prognostic unfavorable (1.20e-5)" "unprognostic (8.02e-2)" "unprognostic (5.72e-2)" "unprognostic (3.38e-3)" "unprognostic (5.62e-2)" "unprognostic (3.64e-2)" "unprognostic (9.35e-2)" "unprognostic (3.44e-2)" "unprognostic (6.51e-3)" "unprognostic (5.68e-2)" "unprognostic (3.44e-2)" "unprognostic (2.37e-1)" "unprognostic (2.53e-1)" "unprognostic (1.01e-1)" "unprognostic (1.72e-1)" "unprognostic (1.66e-1)" "unprognostic (8.73e-2)" "unprognostic (2.60e-1)" ZPLD1 ENSG00000170044 "Zona pellucida like domain containing 1" Q8TCW7 3 102099244-102479841 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 2.1;retina: 2.3" "Cell type enhanced" "Detected in many" "Adrenal medulla cells: 21.3;Breast secretory cells: 19.5;Early spermatids: 63.7;Endometrial glandular cells: 29.3;Epicardial cells: 47.8;Late primary spermatocytes: 70.1;Late spermatids: 44.0;Müller glia: 21.6;Pancreatic duct cells: 32.9;Papillary tip epithelial cells: 78.2;Renal collecting duct principal cells: 45.9;Renal connecting tubule cells: 29.5" "Cell type enhanced" "Detected in many" "Barrier epithelial cells: 47.8;Ductal cells: 45.9;Renal nephron cells: 78.2;Spermatogenic cell types: 70.1" "Cell type enhanced" "Detected in many" "leukocyte: 6.0" "Cancer enhanced" "Detected in some" "Kidney Renal Papillary Cell Carcinoma (TCGA): 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in some" 8 "Rhabdoid: 39.2" "Colon - Colon enteroendocrine cells, Minor Salivary Gland - Minor salivary glandular cells" "Region enriched" "Detected in single" 7 "olfactory bulb: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077519 Approved Nucleoplasm "Intracellular and membrane" "No annotated function" NA NA "Cluster 42: Retina - Visual perception" "Cluster 49: Hindbrain - Mixed function" "Cluster 5: Rhabdoid - Unknown function" "Cluster 51: Secretory epithelial cells - Mixed function" Nucleoplasm "HPA077519: " "unprognostic (2.89e-1)" "unprognostic (4.77e-2)" "unprognostic (1.48e-1)" "unprognostic (1.84e-2)" "unprognostic (3.19e-2)" "potential prognostic unfavorable (1.59e-4)" "unprognostic (2.19e-1)" ZSCAN10 ZNF206 ENSG00000130182 "Zinc finger and SCAN domain containing 10" Q96SZ4 16 3088890-3099295 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Disease variant, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 2.4;Epicardial cells: 2.3;Late spermatids: 1.1;Migrating cytotrophoblasts: 2.2" "Cell type enhanced" "Detected in some" "Barrier epithelial cells: 2.3;Spermatogenic cell types: 1.1;Trophoblast cells: 2.4" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 64 "Testicular Germ Cell Tumor (TCGA): 39.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 5.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA076826 Approved Nucleoplasm,Centrosome NA NA "Cluster 9: Non-specific - Receptor signaling" "Cluster 34: Testis cancer - Unknown function" "Cluster 63: Cytotrophoblasts - Basic cellular functions" 1 Nucleoplasm Centrosome "HPA076826: " "unprognostic (2.87e-2)" ZSCAN16 "dJ265C24.3, FLJ22191, ZNF392, ZNF435" ENSG00000196812 "Zinc finger and SCAN domain containing 16" Q9H4T2 6 28107689-28130082 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 24.6;Cardiomyocytes: 107.3;Oocytes: 41.4" "Cell type enhanced" "Detected in many" "Myocytes: 107.3;Oocytes: 41.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 69.2" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Breast - Breast glandular cells, Minor Salivary Gland - Minor salivary glandular cells, Prostate - Prostate basal glandular cells" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" HPA007290 Supported Approved Nucleoplasm NA NA "Cluster 41: Basophils - Unknown function" "Cluster 17: Intestine - Digestion" "Cluster 11: White matter - Signal transduction" "Cluster 28: Non-specific - Nuclear processes" "Cluster 71: Non-specific - Cardiac endocrine signaling & maintenanc" 9 Nucleoplasm "HPA007290: " "potential prognostic favorable (2.60e-4)" "unprognostic (1.54e-1)" "unprognostic (7.17e-2)" "unprognostic (1.28e-1)" "unprognostic (4.80e-2)" "unprognostic (2.16e-2)" "unprognostic (7.89e-2)" "unprognostic (5.12e-3)" "unprognostic (1.45e-2)" "unprognostic (7.36e-2)" "unprognostic (1.66e-2)" "unprognostic (9.36e-3)" "unprognostic (8.10e-3)" "unprognostic (2.03e-2)" "unprognostic (1.68e-1)" "unprognostic (1.09e-1)" "unprognostic (8.92e-2)" "unprognostic (2.85e-2)" "unprognostic (1.30e-1)" "potential prognostic favorable (2.12e-4)" "unprognostic (1.50e-1)" "unprognostic (1.33e-1)" "unprognostic (6.80e-2)" "unprognostic (2.04e-1)" "potential prognostic favorable (7.84e-7)" "unprognostic (1.96e-2)" "unprognostic (1.53e-2)" "unprognostic (4.77e-2)" "unprognostic (1.19e-1)" "unprognostic (6.18e-2)" "unprognostic (2.93e-1)" ZSCAN18 "FLJ12895, ZNF447" ENSG00000121413 "Zinc finger and SCAN domain containing 18" Q8TBC5 19 58083838-58118427 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Adipose subcutaneous - Smooth muscle cells" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neurons: 15694332.0" "Tissue enriched" "Detected in many" "lymphoid tissue: 21486098.1" HPA024318 Supported Approved "Nucleoplasm,Primary cilium,Basal body,Cytosol" No No "Cluster 22: Eosinophils - Transcription" "Cluster 48: Ciliated tissues - Cilium organization" "Cluster 14: Neurons - Synaptic function" "Cluster 4: Non-specific - Transcription" "Cluster 94: Gonadal somatic cells - Mixed function" 15 Nucleoplasm "Primary cilium, Basal body, Cytosol" "HPA024318: " "unprognostic (1.44e-3)" "unprognostic (4.34e-2)" "unprognostic (5.95e-2)" "unprognostic (1.95e-1)" "unprognostic (1.76e-1)" "unprognostic (2.35e-1)" "unprognostic (3.45e-1)" "unprognostic (3.69e-1)" "unprognostic (6.37e-2)" "unprognostic (2.37e-1)" "validated prognostic favorable (1.64e-6)" "validated prognostic favorable (1.08e-7)" "potential prognostic favorable (1.52e-6)" "unprognostic (3.92e-2)" "unprognostic (2.56e-1)" "unprognostic (2.36e-2)" "unprognostic (3.22e-2)" "unprognostic (4.70e-2)" "unprognostic (1.64e-1)" "unprognostic (1.47e-1)" "unprognostic (2.06e-1)" "unprognostic (3.83e-3)" "unprognostic (2.95e-1)" "unprognostic (2.99e-1)" "unprognostic (3.28e-1)" "unprognostic (1.44e-1)" "unprognostic (4.62e-2)" "unprognostic (3.81e-3)" "unprognostic (3.51e-1)" "unprognostic (1.54e-1)" "unprognostic (6.38e-3)" ZSCAN5A "MGC4161, ZNF495, ZSCAN5" ENSG00000131848 "Zinc finger and SCAN domain containing 5A" Q9BUG6 19 56219670-56368383 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 17.0" "Cell type enhanced" "Detected in many" "Choroid plexus epithelial cells: 247.4;Early spermatids: 270.8;Ependymal cells: 177.9" "Cell type enhanced" "Detected in all" "Ciliated cells: 247.4;Spermatogenic cell types: 270.8" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Testis - Late spermatids" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041263, HPA043123, HPA046836, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Cluster 29: Non-specific - Unknown function" "Cluster 56: Ciliated tissues - Cilium organization" "Cluster 42: Choroid plexus - Mitochondria" "Cluster 4: Non-specific - Transcription" "Cluster 34: Ciliated cells - Cilia assembly & function" 21 "Nuclear speckles" "HPA041263: , HPA043123: , HPA046836: , HPA060667: " "unprognostic (3.79e-2)" "unprognostic (3.37e-1)" "unprognostic (7.30e-2)" "unprognostic (4.56e-1)" "unprognostic (2.89e-3)" "unprognostic (4.36e-3)" "unprognostic (8.57e-3)" "unprognostic (5.74e-2)" "unprognostic (1.39e-1)" "unprognostic (1.09e-1)" "potential prognostic favorable (1.09e-6)" "unprognostic (4.22e-2)" "unprognostic (4.90e-3)" "unprognostic (1.98e-3)" "unprognostic (4.08e-2)" "unprognostic (3.47e-1)" "unprognostic (1.11e-1)" "unprognostic (6.23e-2)" "unprognostic (3.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.04e-1)" "unprognostic (3.54e-2)" "unprognostic (4.86e-1)" "unprognostic (1.18e-1)" "unprognostic (2.86e-3)" "unprognostic (5.31e-2)" "unprognostic (3.64e-1)" "unprognostic (2.03e-1)" "unprognostic (7.21e-2)" "unprognostic (2.81e-2)" "unprognostic (2.46e-1)" ZSCAN5B "ZNF371, ZNF495B" ENSG00000197213 "Zinc finger and SCAN domain containing 5B" A6NJL1 19 56189686-56197815 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 1.7" "Group enriched" "Detected in some" 7 "Differentiating spermatogonia: 7.8;Undifferentiated spermatogonia: 8.0" "Cell type enriched" "Detected in single" 18 "Spermatogenic cell types: 8.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 16 "liver cancer: 1.6" "Testis - Spermatogonia" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043123, HPA046836, HPA059494, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Cluster 67: Testis - Mixed function" "Cluster 15: Kidney cancer - Membrane components" "Cluster 106: Spermatogonia - Spermatogonial differentiation" 1 "Nuclear speckles" "HPA043123: , HPA046836: , HPA059494: , HPA060667: " ZSCAN5C "ZNF495C, ZSCAN5CP" ENSG00000204532 "Zinc finger and SCAN domain containing 5C" A6NGD5 19 56202273-56209461 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041263, HPA043123, HPA046836, HPA060667" Uncertain Uncertain "Nuclear speckles" NA NA "Cluster 53: Squamous epithelial cells - Keratinization" "Cluster 65: Non-specific - Cell growth & division" "Nuclear speckles" "HPA041263: , HPA043123: , HPA046836: , HPA060667: " ZSCAN9 "PRD51, ZNF193" ENSG00000137185 "Zinc finger and SCAN domain containing 9" O15535 6 28224886-28233487 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Early spermatids" "Low region specificity" "Detected in all" "Not detected" "Not detected" "Not detected" "Not detected" "HPA054512, HPA059951" Uncertain Approved Nucleoplasm,Cytosol No No "Cluster 14: Non-specific - Unknown function" "Cluster 67: Testis - Mixed function" "Cluster 50: Non-specific - Nucleic acid binding" "Cluster 28: Non-specific - Nuclear processes" "Cluster 7: Non-specific - Transcription" 26 Nucleoplasm Cytosol "HPA054512: , HPA059951: " "potential prognostic favorable (1.70e-6)" "unprognostic (5.76e-3)" "unprognostic (4.96e-2)" "unprognostic (2.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.52e-2)" "unprognostic (9.31e-3)" "unprognostic (2.76e-2)" "unprognostic (4.92e-2)" "unprognostic (5.64e-2)" "unprognostic (7.68e-3)" "unprognostic (5.51e-2)" "potential prognostic unfavorable (2.47e-5)" "unprognostic (6.52e-2)" "unprognostic (4.04e-2)" "unprognostic (1.23e-1)" "unprognostic (2.23e-2)" "unprognostic (2.70e-1)" "unprognostic (2.60e-1)" "unprognostic (6.08e-2)" "unprognostic (2.77e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-3)" "unprognostic (2.45e-2)" "unprognostic (2.68e-2)" "unprognostic (1.69e-2)" "unprognostic (2.30e-1)" "unprognostic (8.21e-2)" "unprognostic (1.77e-1)" ZSWIM6 KIAA1577 ENSG00000130449 "Zinc finger SWIM-type containing 6" Q9HCJ5 5 61332258-61546172 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Disease variant, Dwarfism, Intellectual disability" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Neutrophils: 3330.7;Podocytes: 1946.6;Respiratory basal cells: 2091.7;Salivary basal cells: 1985.9" "Cell type enhanced" "Detected in many" "Neutrophils: 3330.7" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Stomach - Gastric mucous cells, Testis - Spermatocytes" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enriched" "Detected in single" 223 "Neurons: 22251.6" "Not detected" "Not detected" HPA035938 Uncertain Approved Cytosol NA NA "Cluster 2: Dendritic cells - Unknown function" "Cluster 3: Oligodendrocytes - Myelination" "Cluster 13: Oligodendrocytes - Mixed function" "Cluster 12: Bone cancer - Neuronal signaling" "Cluster 31: Neutrophils - Chemotaxis & Apoptosis" 1 Cytosol "HPA035938: " "unprognostic (4.86e-3)" "unprognostic (2.78e-1)" "unprognostic (2.14e-2)" "unprognostic (6.54e-2)" "unprognostic (1.30e-1)" "unprognostic (1.74e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (3.34e-2)" "unprognostic (9.68e-2)" "unprognostic (8.27e-3)" "unprognostic (1.21e-2)" "unprognostic (3.92e-1)" "unprognostic (1.37e-1)" "unprognostic (2.82e-2)" "unprognostic (3.41e-2)" "unprognostic (2.44e-3)" "unprognostic (1.54e-1)" "unprognostic (5.57e-2)" "unprognostic (2.57e-2)" "unprognostic (6.74e-2)" "unprognostic (4.61e-2)" "unprognostic (9.19e-3)" "unprognostic (9.56e-2)" "unprognostic (1.61e-2)" "unprognostic (1.89e-1)" "unprognostic (3.71e-1)" "unprognostic (9.64e-3)" "unprognostic (6.36e-2)" "unprognostic (1.87e-1)" "unprognostic (9.40e-2)" ZWINT "KNTC2AP, SIP30, Zwint1" ENSG00000122952 "ZW10 interacting kinetochore protein" O95229 10 56357227-56361273 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 39.2;lymphoid tissue: 40.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Differentiating spermatogonia: 103.4;Early primary spermatocytes: 128.6;Early spermatids: 67.1;Enteric transient amplifying cells: 80.7;Erythrocyte progenitors: 93.6;Esophageal basal cells: 91.9;Extravillous trophoblasts: 122.6;Gastric progenitor cells: 103.8;Hofbauer cells: 72.3;Late primary spermatocytes: 141.9;Late spermatids: 301.0;Megakaryocyte progenitors: 80.3;Migrating cytotrophoblasts: 106.8;Oocytes: 138.2" "Cell type enhanced" "Detected in many" "Oocytes: 138.2;Proliferating cells: 103.8;Spermatogenic cell types: 301.0;Trophoblast cells: 122.6" "Cell type enhanced" "Detected in many" "hippocampal CA4: 5.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 17.0" "Lineage enriched" "Detected in many" 5 "T-cells: 17.0" "Low cancer specificity" "Detected in all" "Adrenal gland - Mitotic cells (Adrenal gland), Colon - Mitotic cells (Colon), Lung - Mitotic cells (Lung), Minor Salivary Gland - Mitotic cells (Minor salivary gland), Skin - Mitotic cells (Skin), Spleen - Mitotic cells (Spleen), Stomach - Mitotic cells (Stomach), Testis - Early spermatids" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 2849 "Granulosa cells: 271539.4;Oocytes: 298195.5" "Tissue enriched" "Detected in single" 45 "bone marrow: 4484.2" "HPA005757, HPA022264" Enhanced "Nucleoplasm,Nuclear bodies,Cytosol" No Yes "Cluster 12: Non-specific - Mitochondrial translation" "Cluster 59: Lymphoid tissue & Bone marrow - Cell proliferation" "Cluster 38: Sub-cortical - Mixed function" "Cluster 52: Non-specific - Mitochondria" "Cluster 27: Non-specific - Cell proliferation" 58 "Nucleoplasm, Nuclear bodies" Cytosol "HPA005757: , HPA022264: " "unprognostic (2.15e-2)" "unprognostic (1.13e-2)" "unprognostic (3.07e-2)" "unprognostic (9.00e-3)" "unprognostic (5.55e-2)" "unprognostic (2.02e-1)" "unprognostic (1.59e-1)" "unprognostic (1.78e-2)" "unprognostic (1.76e-1)" "unprognostic (1.72e-3)" "potential prognostic favorable (2.21e-4)" "unprognostic (6.02e-2)" "unprognostic (2.94e-3)" "validated prognostic unfavorable (4.93e-9)" "validated prognostic unfavorable (2.02e-5)" "validated prognostic unfavorable (7.09e-5)" "validated prognostic unfavorable (5.54e-4)" "potential prognostic favorable (7.25e-4)" "unprognostic (6.48e-2)" "unprognostic (1.84e-1)" "unprognostic (2.49e-1)" "unprognostic (1.54e-3)" "unprognostic (9.82e-2)" "unprognostic (3.25e-2)" "unprognostic (1.63e-1)" "unprognostic (1.49e-1)" "unprognostic (6.13e-2)" "unprognostic (4.24e-2)" "unprognostic (2.17e-1)" "unprognostic (3.59e-2)" "unprognostic (1.11e-1)" ZXDC "FLJ13861, MGC11349" ENSG00000070476 "ZXD family zinc finger C" Q2QGD7 3 126437601-126475891 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" Activator "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 37.2" "Cell type enhanced" "Detected in many" "Myonuclei: 292.1" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.4" "Group enriched" "Detected in many" 4 "dendritic cells: 1.1;granulocytes: 1.7;monocytes: 4.4" "Low cancer specificity" "Detected in all" "Minor Salivary Gland - Minor salivary glandular cells, Testis - Spermatogonia" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" "Fallopian tube cells: 3374.8;Granulosa cells: 6611.5;Neurons: 12953.4" "Not detected" "Not detected" HPA049593 Approved Nucleoli Yes No "Cluster 7: Non-specific - Innate immune response" "Cluster 63: Non-specific - Basic cellular processes" "Cluster 6: Non-specific - Immune response" "Cluster 63: Non-specific - Protein processing" "Cluster 55: Myocytes - Oxidative muscle function" 24 Nucleoli "HPA049593: " "unprognostic (4.05e-2)" "unprognostic (1.23e-1)" "unprognostic (2.18e-1)" "unprognostic (9.81e-2)" "unprognostic (1.21e-1)" "unprognostic (2.79e-2)" "unprognostic (1.17e-1)" "unprognostic (6.08e-2)" "unprognostic (2.40e-1)" "unprognostic (4.05e-2)" "potential prognostic favorable (1.12e-6)" "unprognostic (1.55e-2)" "unprognostic (3.69e-1)" "unprognostic (4.42e-3)" "unprognostic (3.47e-2)" "unprognostic (1.19e-1)" "unprognostic (2.48e-1)" "unprognostic (1.59e-3)" "unprognostic (1.27e-1)" "unprognostic (3.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.90e-1)" "unprognostic (1.16e-1)" "unprognostic (2.55e-1)" "unprognostic (1.96e-2)" "unprognostic (4.72e-3)" "unprognostic (1.19e-2)" "unprognostic (1.11e-1)" "unprognostic (2.32e-1)" "unprognostic (3.26e-2)" "unprognostic (1.26e-1)" ZZZ3 "ATAC1, DKFZP564I052" ENSG00000036549 "Zinc finger ZZ-type containing 3" Q8IYH5 1 77562416-77683419 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Thyroid gland - Thyroid glandular cells" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Macrophages: 339818.2;Neurons: 212128.5" "Tissue enriched" "Detected in single" 49 "lymphoid tissue: 4936.9" "HPA053663, HPA054913, HPA066197" Uncertain Enhanced "Nucleoplasm,Nucleoli,Nucleoli rim" No No "Cluster 3: Non-specific - Nuclear processes" "Cluster 61: Non-specific - Transcription" "Cluster 28: Oligodendrocytes - Mixed function" "Cluster 37: Non-specific - mRNA processing" "Cluster 7: Non-specific - Transcription" 24 "Nucleoplasm, Nucleoli, Nucleoli rim" "HPA053663: , HPA054913: , HPA066197: " "unprognostic (2.43e-1)" "unprognostic (9.97e-2)" "unprognostic (1.07e-1)" "unprognostic (1.90e-3)" "unprognostic (3.18e-2)" "unprognostic (1.11e-1)" "unprognostic (5.84e-2)" "unprognostic (2.22e-3)" "unprognostic (3.40e-2)" "unprognostic (7.21e-2)" "potential prognostic favorable (8.33e-8)" "unprognostic (5.25e-3)" "unprognostic (2.23e-1)" "unprognostic (7.84e-2)" "unprognostic (2.29e-1)" "unprognostic (1.09e-1)" "unprognostic (7.70e-2)" "unprognostic (6.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.35e-2)" "unprognostic (1.81e-2)" "unprognostic (3.02e-2)" "unprognostic (2.35e-2)" "unprognostic (1.06e-1)" "unprognostic (6.87e-3)" "unprognostic (1.06e-1)" "unprognostic (1.74e-1)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (1.03e-2)" "unprognostic (2.18e-1)"