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Tissue Tau score (RNA)
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Brain Tau score (RNA)
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Mouse brain Tau score (RNA)
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Pig brain Tau score (RNA)
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Reliability score mouse brain
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Cell type Tau score (RNA)
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Cell type group Tau score (RNA)
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Brain region Tau score (scRNA)
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Immune cell Tau score (RNA)
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Immune cell lineage Tau score (RNA)
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Blood group antigen proteins
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Mapped to neXtProt
Mapped to UniProt SWISS-PROT
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Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
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Subclass
Category
Biological process
Molecular function
Disease
Keyword
Chromosome
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
MT
Unmapped
X
Y
External id
Tissue
Any
Adipose tissue
Adrenal gland
Appendix
Bone marrow
Breast
Bronchus
Brown adipose tissue
Cartilage
Caudate
Cerebellum
Cerebral cortex
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Retina
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Skin
Small intestine
Smooth muscle
Soft tissue
Sole of foot
Spleen
Stomach
Substantia nigra
Testis
Thymus
Thyroid gland
Tonsil
Urinary bladder
Vagina
Cell type
Expression
Antibody panel
Any
Ciliated cells
Kidney
Pancreas
Salivary gland
Sertoli cells
Spermatids
Spermatocytes
Spermatogonia
Tissue
Main location
Patient ID
Annotation
Immunoglobulin genes
Intracellular and membrane
Secreted - unknown location
Secreted in brain
Secreted in female reproductive system
Secreted in male reproductive system
Secreted in other tissues
Secreted to blood
Secreted to digestive system
Secreted to extracellular matrix
Tissue
Any
Adipose tissue
Adrenal gland
Blood vessel
Bone marrow
Brain
Breast
Cervix
Choroid plexus
Endometrium
Epididymis
Esophagus
Fallopian tube
Gallbladder
Heart muscle
Intestine
Kidney
Liver
Lung
Lymphoid tissue
Ovary
Pancreas
Parathyroid gland
Pituitary gland
Placenta
Prostate
Retina
Salivary gland
Seminal vesicle
Skeletal muscle
Skin
Smooth muscle
Stomach
Testis
Thyroid gland
Tongue
Urinary bladder
Vagina
Category
Tissue enriched
Group enriched
Tissue enhanced
Low tissue specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Cluster
14:Adipose tissue - Angiogenesis
4:Adrenal gland - Steroid metabolism
15:Bone marrow - Innate immune response
44:Bone marrow - Nuclear processes
73:Brain - Neuronal signaling
78:Brain - Neuronal signaling
10:Brain - Synaptic signal transduction
65:Brain - Transcription
36:Brain & Liver - Signaling
46:Brain & retina - Neuronal signaling
55:Breast - Lactation
71:Cerebellum - Nervous system development
27:Cerebellum - Synaptic function
1:Choroid plexus - Transmembrane transport
48:Ciliated tissues - Cilium organization
56:Ciliated tissues - Cilium organization
50:Epididymis - Male reproductive secretion
22:Epididymis - Mixed function
11:Esophagus - Basic cellular processes
17:Intestine - Digestion
77:Intestine - Digestion
72:Kidney - Transmembrane transport
26:Kidney & Intestine - Metabolism
31:Liver - Metabolism & Coagulation
45:Liver - Metabolism & Coagulation
53:Liver - Plasma proteins
28:Liver & Adrenal gland - Secretion
16:Liver & Kidney - Metabolism
13:Lung - Secretion
34:Lymphoid tissue - Adaptive immune response
51:Lymphoid tissue - Adaptive immune response
18:Lymphoid tissue - Immune response
66:Lymphoid tissue - Immune response
59:Lymphoid tissue & Bone marrow - Cell proliferation
29:Lymphoid tissue & Bone marrow - Innate immune response
25:Non-specific - Basic cellular processes
38:Non-specific - Basic cellular processes
63:Non-specific - Basic cellular processes
68:Non-specific - Basic cellular processes
52:Non-specific - Cellular respiration
76:Non-specific - Metabolism
2:Non-specific - Mixed function
35:Non-specific - Mixed function
40:Non-specific - Mixed function
70:Non-specific - Protein processing
54:Non-specific - Ribosome
74:Non-specific - Signal transduction
24:Non-specific - Transcription
49:Non-specific - Transcription
61:Non-specific - Transcription
64:Non-specific - Transcription
3:Oligodendrocytes - Myelination
75:Ovary - Mixed function
8:Pancreas - Proteolysis
69:Parathyroid gland - Mixed function
20:Pituitary gland - Hormone signaling
43:Placenta - Pregnancy hormone signaling
42:Retina - Visual perception
32:Retina & Lymphoid tissues - Signaling
82:Salivary gland - Secretion
62:Skeletal muscle - Muscle contraction
19:Skeletal muscle - Striated muscle contraction
30:Skeletal muscle - Striated muscle contraction
9:Skin - Hair follicle development
37:Skin - Keratinization
58:Skin - Keratinization
7:Small intestine - Absorption and Digestion
12:Smooth muscle tissue - ECM organization
5:Spleen - Immune response
81:Squamous epithelium - Keratinization
60:Stomach - Digestion
41:Striated muscle - Muscle contraction
21:Testis - Mixed function
47:Testis - Mixed function
67:Testis - Mixed function
39:Testis - Nuclear processes
6:Testis - Spermatogenesis
23:Testis - Spermatogenesis
57:Testis - Spermatogenesis
79:Testis - Spermatogenesis
80:Thymus - Adaptive immune response
33:Thyroid gland - Tissue development
Reliability
Enhanced
Supported
Approved
Uncertain
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Choroid plexus
Hippocampal formation
Hypothalamus
Medulla oblongata
Midbrain
Pons
Spinal cord
Thalamus
White matter
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Hippocampal formation
Hypothalamus
Midbrain
Olfactory bulb
Pons and medulla
Thalamus
White matter
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Brain region
Any
Amygdala
Basal ganglia
Cerebellum
Cerebral cortex
Hippocampal formation
Hypothalamus
Medulla oblongata
Midbrain
Olfactory bulb
Pons
Spinal cord
Thalamus
White matter
Category
Region enriched
Group enriched
Region enhanced
Low region specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Cluster
40:Astrocytes - Astrocyte-neuron interactions
19:Astrocytes - Mixed function
39:Astrocytes - Mixed function
46:Brainstem - Mixed function
10:Cerebellum - Nucleic acid binding
32:Cerebral cortex - Mixed function
3:Choroid plexus - Cilium
17:Choroid plexus - Cilium
42:Choroid plexus - Mitochondria
23:Choroid plexus - Mixed function
36:Choroid plexus - Mixed function
47:Endothelial cells - Vasculature
29:Forebrain - Mixed function
43:Hindbrain - Mixed function
49:Hindbrain - Mixed function
56:Hypothalamus - Neuropeptide signaling
8:Immune cells - Immune response
54:Immune cells - T cell receptor
20:Macrophages & Microglia - Immune response
41:Monoamines - Neurotransmitter signalling
1:Neurons - Mixed function
24:Neurons - Mixed function
33:Neurons - Mixed function
37:Neurons - Mixed function
51:Neurons - Mixed function
53:Neurons - Mixed function
2:Neurons - Nucleosome
14:Neurons - Synaptic function
52:Neurons & Synapses - Synaptic function
35:Non-specific - DNA binding
6:Non-specific - Immune response
21:Non-specific - Metabolism
5:Non-specific - Mixed function
18:Non-specific - Mixed function
22:Non-specific - Mixed function
27:Non-specific - Mixed function
34:Non-specific - Mixed function
44:Non-specific - Mixed function
45:Non-specific - Mixed function
48:Non-specific - Mixed function
4:Non-specific - mRNA splicing & Cell cycle
50:Non-specific - Nucleic acid binding
9:Non-specific - Receptor signaling
7:Non-specific - Ribosome
15:Non-specific - Transcription
16:Non-specific - Transcription
25:Non-specific - Transcription
31:Non-specific - Transcription
55:Non-specific - Transcription
12:Non-specific - Vasculature
13:Oligodendrocytes - Mixed function
26:Oligodendrocytes - Mixed function
28:Oligodendrocytes - Mixed function
38:Sub-cortical - Mixed function
30:White matter - Myelination
11:White matter - Signal transduction
Reliability
Supported
Approved
Tissue
Adipose subcutaneous
Adipose visceral
Adrenal gland
Breast
Colon
Heart muscle
Kidney
Liver
Lung
Minor Salivary Gland
Pancreas
Pituitary gland
Prostate
Skeletal muscle
Skin
Spleen
Stomach
Testis
Thyroid gland
Cell type
Enrichment
Cell type
Any
Adipocytes
Adrenal cortex cells
Adrenal medulla cells
Alveolar cells type 1
Alveolar cells type 2
Astrocytes
B-cells
Basal keratinocytes
Basal prostatic cells
Bergmann glia
Brain excitatory neurons
Brain inhibitory neurons
Breast hormone-responsive cells
Breast lactating cells
Breast myoepithelial cells
Breast secretory cells
Cardiomyocytes
CDC
Cholangiocytes
Choroid plexus epithelial cells
Colonocytes
Cone photoreceptor cells
Conjunctival goblet cells
Corticotrophs
Cytotrophoblasts
Decidual stromal cells
Differentiating spermatogonia
Distal convoluted tubule cells
Early primary spermatocytes
Early spermatids
Endometrial ciliated cells
Endometrial glandular cells
Endometrial luminal cells
Endometrial secretory cells
Endometrial stromal cells
Enteric stem cells
Enteric transient amplifying cells
Enterocytes
Ependymal cells
Epicardial cells
Epididymal basal cells
Epididymal clear cells
Epididymal efferent duct absorptive cells
Epididymal efferent duct ciliated cells
Epididymal principal cells
Erythrocyte progenitors
Erythrocytes
Esophageal apical cells
Esophageal basal cells
Esophageal suprabasal cells
Extravillous trophoblasts
Fallopian secretory cells
Fallopian tube ciliated cells
Fibro-adipogenic progenitors
Fibroblasts
Foveolar cells
Gastric chief cells
Gastric progenitor cells
Goblet cells
Gonadotrophs
Granulosa cells
Hematopoietic stem cells
Hepatic stellate cells
Hepatocytes
Hofbauer cells
Innate lymphoid cells
Kupffer cells
Lacrimal acinar cells
Lactotrophs
Late primary spermatocytes
Late spermatids
Leydig cells
Loop of henle epithelial cells
Lymphatic endothelial cells
Macrophages
Mast cells
Medullary thymic epithelial cells
Megakaryocyte progenitors
Megakaryocyte-Erythroid progenitors
Megakaryocytes
Melanocytes
Mesothelial cells
Microglia
Migrating cytotrophoblasts
Monocyte progenitors
Monocytes
Mucous neck cells
Müller glia
Myonuclei
Myosatellite cells
Neuroendocrine cells
Neutrophil progenitors
Neutrophils
NK-cells
Ocular epithelial cells
Oligodendrocyte progenitor cells
Oligodendrocytes
Oocytes
Other brain neurons
Ovarian stromal cells
Pancreatic acinar cells
Pancreatic duct cells
Pancreatic islet cells
Paneth cells
Papillary tip epithelial cells
Parietal cells
PDCs
Pericytes
Peritubular myoid cells
Pituicytes/FSCs
Pituitary stem cells
Plasma cells
Platelets
Podocytes
Prostatic club cells
Prostatic glandular cells
Prostatic hillock cells
Proximal tubule cells
Renal collecting duct intercalated cells
Renal collecting duct principal cells
Renal connecting tubule cells
Respiratory basal cells
Respiratory ciliated cells
Respiratory deuterosomal cells
Respiratory ionocytes
Respiratory secretory cells
Retinal amacrine cells
Retinal bipolar cells
Retinal ganglion cells
Retinal horizontal cells
Retinal pigment epithelial cells
Rod photoreceptor cells
Salivary acinar cells
Salivary basal cells
Salivary duct cells
Salivary ionocytes
Salivary myoepithelial cells
Schwann cells
Sertoli cells
Smooth muscle cells
Somatotrophs
Submucosal glandular cells
Suprabasal keratinocytes
Syncytiotrophoblasts
T-cells
Thymic myoid cells
Thymocytes
Thyrotrophs
Transitional alveolar cells
Tuft cells
Undifferentiated spermatogonia
Urothelial cells
Vascular endothelial cells
Vascular smooth muscle cells
Category
Cell type enriched
Group enriched
Cell type enhanced
Low cell type specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Cell type group
Any
Acinar cells
Adipocytes
Adrenal endocrine cells
Alveolar cells
Apical squamous epithelial cells
B-cells
Barrier epithelial cells
Basal cells
Ciliated cells
Dendritic cells
Ductal cells
Endothelial cells
Enterocytes
Enteroendocrine cells
Erythrocytes
Fibro-adipogenic progenitors
Fibroblasts
Gastric glandular cells
Glandular cells
Glial cells
Goblet cells
Hepatocytes
Innate lymphoid cells
Ionocytes
Leydig cells
Luminal cells
Mast cells
Megakaryocytes
Mononuclear phagocytes
Mural cells
Myocytes
Neuronal cells
Neutrophils
NK-cells
Oocytes
Pancreatic islet cells
Pigment cells
Pituitary endocrine cells
Plasma cells
Platelets
Proliferating cells
Renal nephron cells
Reproductive supporting cells
Secretory cells
Secretory gland support
Smooth muscle cells
Spermatogenic cell types
Stellate cells
Stem cells
Stromal cells
Suprabasal cells
T-cells
Trophoblast cells
Category
Cell type enriched
Group enriched
Cell type enhanced
Low cell type specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Cell type
Any
Amygdala excitatory
Astrocyte
Bergmann glia
Central nervous system macrophage
Cerebellar inhibitory
CGE interneuron
Choroid plexus epithelial cell
Committed oligodendrocyte precursor
Deep-layer corticothalamic and 6b
Deep-layer intratelencephalic
Deep-layer near-projecting
Eccentric medium spiny neuron
Endothelial cell
Ependymal cell
Fibroblast
Hippocampal CA1-3
Hippocampal CA4
Hippocampal dentate gyrus
LAMP5-LHX6 and Chandelier
Leukocyte
Lower rhombic lip
Mammillary body
Medium spiny neuron
MGE interneuron
Midbrain-derived inhibitory
Miscellaneous
Oligodendrocyte
Oligodendrocyte precursor cell
Pericyte
Splatter
Thalamic excitatory
Upper rhombic lip
Upper-layer intratelencephalic
Vascular associated smooth muscle cell
Category
Cell type enriched
Group enriched
Cell type enhanced
Low cell type specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Cell type
Any
Basophil
Classical monocyte
Eosinophil
GdT-cell
Intermediate monocyte
MAIT T-cell
Memory B-cell
Memory CD4 T-cell
Memory CD8 T-cell
Myeloid DC
Naive B-cell
Naive CD4 T-cell
Naive CD8 T-cell
Neutrophil
NK-cell
Non-classical monocyte
Plasmacytoid DC
T-reg
Total PBMC
Category
Immune cell enriched
Group enriched
Immune cell enhanced
Low immune cell specificity
Not detected in immune cells
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Cell lineage
Any
B-cells
Dendritic cells
Granulocytes
Monocytes
NK-cells
T-cells
Category
Lineage enriched
Group enriched
Lineage enhanced
Low lineage specificity
Not detected
Detected in all
Detected in many
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Cluster
17:B-cells - Immunoglobulins
23:B-cells - Immunoglobulins
34:B-cells - Unknown function
46:Basophils - Proteolysis
32:Basophils - Transcription
41:Basophils - Unknown function
2:Dendritic cells - Unknown function
36:Eosinophils - Protein ubiquitination
22:Eosinophils - Transcription
19:Eosinophils - Unknown function
45:Eosinophils - Unknown function
40:Monocytes - Innate immune response
26:Monocytes - Plasma membrane proteins
38:Monocytes & Neutrophils - Degranulation
37:Monocytes & Neutrophils - Innate immune response
4:Neutrophils - Degranulation
35:Neutrophils - Protein binding
21:Neutrophils - Unknown function
28:Neutrophils - Unknown function
15:NK-cells - Unknown function
33:Non-specific - ATP binding
5:Non-specific - Cell proliferation
16:Non-specific - Cell proliferation
20:Non-specific - DNA binding
30:Non-specific - DNA binding
7:Non-specific - Innate immune response
10:Non-specific - Membrane trafficking
13:Non-specific - Mitochondria
12:Non-specific - Mitochondrial translation
3:Non-specific - Nuclear processes
24:Non-specific - Transcription
43:Non-specific - Transcription & Translation
18:Non-specific - Translation
14:Non-specific - Unknown function
25:Non-specific - Unknown function
29:Non-specific - Unknown function
42:Non-specific - Vesicular transport
44:Plasmacytoid DCs - Plasma membrane proteins
8:Plasmacytoid DCs - Unknown function
6:T-cells - T-cell receptor
31:T-cells - T-cell receptor
39:T-cells - T-cell receptor
1:T-cells - Unknown function
11:T-cells - Unknown function
27:T-cells - Unknown function
9:T-regs - Cell cycle regulation
Cluster
89:Adipocytes - Lipid metabolism
18:Adrenal cortex cells - Steroidogensis
81:Alveolar cells - Lung function
84:Apical squamous epithelium - Cornification
49:Apical squamous epithelium - Epithelial barrier & keratinization
28:Astrocytes - Homeostasis & neuron support
87:B-cells - Adaptive immunity: Humoral response
104:Brain endothelial cells - Blood brain barrier
4:Breast lactating luminal cells - Lactation
60:Cardiomyocytes - Cardiac muscle contraction & structure
2:Cerebellar granular cells - Neuronal signaling
19:Cerebellar purkinje cells - Neurotransmission & signaling
101:Choroid plexus epithelial cells - Ion transport
34:Ciliated cells - Cilia assembly & function
107:Ciliated cells - Cilia assembly & function
45:Colonocytes & Enterocytes - Gastrointestinal absorption & barrier
63:Cytotrophoblasts - Basic cellular functions
82:Dendritic cells - Antigen presentation
3:Early primary spermatocytes - Early meiosis
42:Early spermatids - Spermiogenesis: Acrosomal phase
33:Early spermatids - Spermiogenesis: Cap phase
23:Elongating spermatids - Sperm cell metabolism & fertilization
90:Elongating spermatids - Spermiogenesis: Elongation
12:Endothelial cells - Angiogenesis & vascular homeostasis
32:Endothelial cells - Angiogenesis & vascular immunity
1:Enterocytes - Absorption and Digestion
96:Enteroendocrine cells - Neuropeptide signaling
83:Epicardial mesothelial cells - Basic cellular functions
10:Epididymal principal cells - Sperm maturation microenvironment
30:Epididymal principal cells - Sperm storage microenvironment
66:Erythroid cells - Erythroid differentiation and maturation
21:Extravillous trophoblasts - Placental invasion & endocrine regulatio
108:Fibroblasts - ECM organization
68:Foveolar cells - Mucosal defense
52:Glandular & Luminal cells - Estrogen-regulated epithelial secretion
94:Gonadal somatic cells - Mixed function
93:Hepatocytes - Bile production & excretion
25:Hepatocytes - Plasma protein synthesis & secretion
54:Intestinal epithelial cells - Intestinal epi homeostasis & respiration
70:Intestinal goblet cells - Mucin production
26:Keratinocytes - Keratinization
53:Late primary spermatocytes - Meiotic division & transition
77:Late primary spermatocytes - Spermiogenesis: Golgi Phase
56:Late spermatids - Spermiogenesis: Maturation
73:Late spermatids - Spermiogenesis: Maturation
72:Macrophages - Phagocytosis & lysosomal degradation
58:Mast cells - Allergic inflammatory responses
74:Microglia - Neuroimmunity & neuroinflammation
40:Monocytes & Neutrophils - Inflammatory signaling
11:Muller glia cells - Retinal homeostasis
110:Mural cells - ECM organization
55:Myocytes - Oxidative muscle function
109:Neurons - Neuronal signaling
98:Neurons - Neurotransmission & signaling
35:Neurons - Synaptic function & neurogenesis
37:Neutrophil progenitors - Granulopoiesis
31:Neutrophils - Chemotaxis & Apoptosis
29:Neutrophils - Innate immune cellular maintenance
24:Neutrophils - Innate immunity signal integration
48:Neutrophils - Phagocytosis & degranulation
92:NK-cells & T-cells - Adaptive immunity: Cytotoxicity
22:Non-specific - Basic cellular functions
103:Non-specific - Basic cellular processes
71:Non-specific - Cardiac endocrine signaling & maintenanc
65:Non-specific - Cell growth & division
27:Non-specific - Cell proliferation
97:Non-specific - Cellular respiration
75:Non-specific - Chaperones and protein folding
102:Non-specific - Mixed function
105:Non-specific - Mixed function
15:Non-specific - Protein processing
17:Non-specific - RNA processing
8:Non-specific - Secretory pathway
7:Non-specific - Transcription
20:Non-specific - Transcription regulation
14:Oligodendrocyte progenitor cells - Development & myelination
80:Oligodendrocytes - Myelination
41:Oocytes - Oogenesis
5:Pancreatic acinar cells - Pancreatic exocrine secretion
76:Pancreatic endocrine cells - Endocrine signaling
79:Photoreceptor cells - Phototransduction
91:Pituicytes/FSC - Homeostasis & neuron support
59:Pituitary endocrine cells - Neuroendocrine signaling
78:Plasma cells - Antibody production & ER-stress response
44:Plasma cells - Antibody production & secretion
67:Plasma cells - Plasma cell differentiation
6:Plasmacytoid dendritic cells - Viral sensing & interferon response
47:Platelets - Hemostasis
57:Podocytes - Glomerular filtration
16:Prostatic glandular cells - Androgen response & seminal fluid
88:Proximal tubular cells - Transmembrane transport
64:Renal epithelial cells - Ion transport & homeostasis
50:Renal epithelial cells - Ion transport and pH regulation
86:Retinal bipolar cells - Synaptic signal transduction
99:Retinal pigment epithelial cells - Retinol metabolism
61:Schwann cells & Melanocytes - Mixed function
38:Secretory epithelial cells - Exocrine secretion
51:Secretory epithelial cells - Mixed function
43:Sertoli cells - Spermatogenesis microenvironment
36:Skeletal myocytes - Muscle excitation & contraction
46:Skeletal myocytes - Muscle structure & formation
62:Smooth muscle cells - Muscle contraction
106:Spermatogonia - Spermatogonial differentiation
85:Squamous epithelial cells - Keratinization
100:Stratified epithelial cells - Barrier functions
39:Syncytiotrophoblasts - Placental homeostasis & endocrine signal
13:Syncytiotrophoblasts - Placental remodeling & endocrine func.
9:T-cells - Adaptive immunity: Regulation
95:Tuft cells - Chemosensory signaling
69:Urothelial cells - Basic cellular functions
Location
Acrosome
Actin filaments
Aggresome
Annulus
Basal body
Calyx
Cell Junctions
Centriolar satellite
Centrosome
Cleavage furrow
Connecting piece
Cytokinetic bridge
Cytoplasmic bodies
Cytosol
End piece
Endoplasmic reticulum
Endosomes
Equatorial segment
Flagellar centriole
Focal adhesion sites
Golgi apparatus
Intermediate filaments
Kinetochore
Lipid droplets
Lysosomes
Microtubule ends
Microtubules
Mid piece
Midbody
Midbody ring
Mitochondria
Mitotic chromosome
Mitotic spindle
Nuclear bodies
Nuclear membrane
Nuclear speckles
Nucleoli
Nucleoli fibrillar center
Nucleoli rim
Nucleoplasm
Perinuclear theca
Peroxisomes
Plasma membrane
Primary cilium
Primary cilium tip
Primary cilium transition zone
Principal piece
Rods & Rings
Vesicles
Searches
Enhanced
Supported
Approved
Uncertain
Single cell variation
CCD protein mitotic structure
CCD protein interphase
Cell cycle dependent protein
Cell cycle independent protein
Cell cycle dependent transcript
Cell cycle independent transcript
Multilocalizing
Localizing 1
Localizing 2
Localizing 3
Localizing 4
Localizing 5
Localizing 6
Main location
Additional location
Location
Any
Acrosome
Actin filaments
Aggresome
Annulus
Basal body
Calyx
Cell Junctions
Centriolar satellite
Centrosome
Cleavage furrow
Connecting piece
Cytokinetic bridge
Cytoplasmic bodies
Cytosol
End piece
Endoplasmic reticulum
Endosomes
Equatorial segment
Flagellar centriole
Focal adhesion sites
Golgi apparatus
Intermediate filaments
Kinetochore
Lipid droplets
Lysosomes
Microtubule ends
Microtubules
Mid piece
Midbody
Midbody ring
Mitochondria
Mitotic chromosome
Mitotic spindle
Nuclear bodies
Nuclear membrane
Nuclear speckles
Nucleoli
Nucleoli fibrillar center
Nucleoli rim
Nucleoplasm
Perinuclear theca
Peroxisomes
Plasma membrane
Primary cilium
Primary cilium tip
Primary cilium transition zone
Principal piece
Rods & Rings
Vesicles
Cell line
Any
A-431
A-549
AF22
ASC52telo
BJ [Human fibroblast]
CACO-2
EFO-21
GAMG
HaCaT
HAP1
HBEC3-KT
HDLM-2
HEK293
HEL
HeLa
Hep-G2
HTCEpi
HTERT-RPE1
HTERT-RPE1 (serum starved)
HUVEC/TERT2
JURKAT
K-562
KOLF2.1J
LHCN-M2
MCF-7
NB4
OE19
PC-3
PODO/SVTERT152
PODO/TERT256
REH
Rh30
RPTEC/TERT1
RT-4
SH-SY5Y
SiHa
SK-MEL-30
Sperm
SuSa
THP-1
U-251MG
U2OS
Class
Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Type
Protein
Rna
Phase
G1
S
G2
Reliability
Enhanced
Supported
Approved
Uncertain
Cancer
Bladder Urothelial Carcinoma
Breast Invasive Carcinoma
Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma
Colon Adenocarcinoma
Glioblastoma Multiforme
Head and Neck Squamous Cell Carcinoma
Kidney Chromophobe
Kidney Renal Clear Cell Carcinoma
Kidney Renal Papillary Cell Carcinoma
Liver Hepatocellular Carcinoma
Lung Adenocarcinoma
Lung Squamous Cell Carcinoma
Ovary Serous Cystadenocarcinoma
Pancreatic Adenocarcinoma
Prostate Adenocarcinoma
Rectum Adenocarcinoma
Skin Cutaneous Melanoma
Stomach Adenocarcinoma
Testicular Germ Cell Tumor
Thyroid Carcinoma
Uterine Corpus Endometrial Carcinoma
Prognosis
Favorable - potential prognostic
Favorable - validated prognostic
Unfavorable - potential prognostic
Unfavorable - validated prognostic
Cancer
Any
Bladder Urothelial Carcinoma
Breast Invasive Carcinoma
Cervical Squamous Cell Carcinoma and Endocervical Adenocarcinoma
Colon Adenocarcinoma
Glioblastoma Multiforme
Head and Neck Squamous Cell Carcinoma
Kidney Chromophobe
Kidney Renal Clear Cell Carcinoma
Kidney Renal Papillary Cell Carcinoma
Liver Hepatocellular Carcinoma
Lung Adenocarcinoma
Lung Squamous Cell Carcinoma
Ovary Serous Cystadenocarcinoma
Pancreatic Adenocarcinoma
Prostate Adenocarcinoma
Rectum Adenocarcinoma
Skin Cutaneous Melanoma
Stomach Adenocarcinoma
Testicular Germ Cell Tumor
Thyroid Carcinoma
Uterine Corpus Endometrial Carcinoma
Category
Cancer enriched
Group enriched
Cancer enhanced
Low cancer specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Cancer
Any
Adrenocortical cancer
Bile duct cancer
Bladder cancer
Bone cancer
Brain cancer
Breast cancer
Cervical cancer
Colorectal cancer
Esophageal cancer
Gallbladder cancer
Gastric cancer
Head and neck cancer
Kidney cancer
Leukemia
Liver cancer
Lung cancer
Lymphoma
Myeloma
Neuroblastoma
Non-cancerous
Ovarian cancer
Pancreatic cancer
Prostate cancer
Rhabdoid
Sarcoma
Skin cancer
Testis cancer
Thyroid cancer
Uncategorized
Uterine cancer
Category
Cancer enriched
Group enriched
Cancer enhanced
Low cancer specificity
Not detected
Detected in all
Detected in many
Detected in some
Detected in single
Is highest expressed
Tau score
0.0-0.1
0.1-0.2
0.2-0.3
0.3-0.4
0.4-0.5
0.5-0.6
0.6-0.7
0.7-0.8
0.8-0.9
0.9-1.0
Cluster
48:Adipocytes & Endothelial cells - Angiogenesis
61:BICR 18 - Protein kinases
12:Bone cancer - Neuronal signaling
27:Breast cancer - Unknown function
10:Ciliated cells - Ion channel activity
44:Connective tissue cells - ECM organization
64:Connective tissue cells - ECM organization
70:DU4475 - Unknown function
49:HMC-1 - Innate immune response
15:Kidney cancer - Membrane components
47:Leukemia - Hemostasis
6:Leukemia - Signal transduction
59:Leukemia - T-cell receptor
7:Liver cancer - Metabolism
18:Liver cancer - Metabolism
21:Lymphoma - Adaptive immune response
46:Lymphoma - Humoral immune response
55:Lymphoma - Immune response
71:Lymphoma - Inflammatory response
50:Lymphoma - Unknown function
2:Mucus-secreting cells - Unknown function
14:Myeloid leukemia - Innate immune response
20:Myeloma - Immune response
51:Myeloma - Immunoglobulins
17:Neuroblastoma - Neuronal signaling
11:Neuronal - Sensory perception
72:Neuronal - Signal transduction
1:Neuronal - Visual perception
31:Non-specific - Antiviral immune response
8:Non-specific - Basic cellular processes
43:Non-specific - Basic cellular processes
68:Non-specific - Cell cycle regulation
32:Non-specific - Cell proliferation
30:Non-specific - Gene expression regulation
52:Non-specific - Mitochondria
66:Non-specific - Mitochondria
26:Non-specific - Mitochondria & RNA binding
13:Non-specific - Mixed function
36:Non-specific - mRNA processing
37:Non-specific - mRNA processing
22:Non-specific - mRNA splicing & Cell cycle
28:Non-specific - Nuclear processes
45:Non-specific - Nuclear processes
58:Non-specific - Nuclear processes
41:Non-specific - Nucleosome assembly
62:Non-specific - Plasma proteins
63:Non-specific - Protein processing
25:Non-specific - Ribosome
56:Non-specific - Sensory perception
4:Non-specific - Transcription
23:Non-specific - Transcription
38:Non-specific - Transcription
39:Non-specific - Transcription
54:Non-specific - Transcription
19:Non-specific - Unknown function
24:Non-specific - Unknown function
29:Non-specific - Unknown function
40:Non-specific - Unknown function
42:Non-specific - Unknown function
65:Non-specific - Unknown function
67:Non-specific - Unknown function
60:Prostate cancer - Unknown function
3:Rhabdoid - Membrane components
5:Rhabdoid - Unknown function
35:RS4;11 - Unknown function
33:Sarcoma - Muscle contraction
69:Skin cancer - ECM organization
9:Skin cancer - Melanin biosynthesis
53:Squamous epithelial cells - Keratinization
57:Stomach & Colon cancer - Digestion
34:Testis cancer - Unknown function
16:Thyroid cancer - Neuronal signaling
Variants
Alphamissense population
Alphamissense clinical
Experimental Population
Experimental clinical
Interacting gene (ensg_id)
Type
Consensus
IntAct
BioGrid
OpenCell
BioPlex
Number of interactions
1
2
3
4
5
6-10
11-20
21-30
31-40
41-50
51-75
76-100
101-200
>200
Pathway
Acyl-CoA hydrolysis
Acylglycerides metabolism
Alanine; aspartate and glutamate metabolism
Amino sugar and nucleotide sugar metabolism
Aminoacyl-tRNA biosynthesis
Androgen metabolism
Arachidonic acid metabolism
Arginine and proline metabolism
Ascorbate and aldarate metabolism
Beta oxidation of branched-chain fatty acids (mitochondrial)
Beta oxidation of di-unsaturated fatty acids (n-6) (mitochondrial)
Beta oxidation of di-unsaturated fatty acids (n-6) (peroxisomal)
Beta oxidation of even-chain fatty acids (mitochondrial)
Beta oxidation of even-chain fatty acids (peroxisomal)
Beta oxidation of odd-chain fatty acids (mitochondrial)
Beta oxidation of phytanic acid (peroxisomal)
Beta oxidation of poly-unsaturated fatty acids (mitochondrial)
Beta oxidation of unsaturated fatty acids (n-7) (mitochondrial)
Beta oxidation of unsaturated fatty acids (n-7) (peroxisomal)
Beta oxidation of unsaturated fatty acids (n-9) (mitochondrial)
Beta oxidation of unsaturated fatty acids (n-9) (peroxisomal)
Beta-alanine metabolism
Bile acid biosynthesis
Bile acid recycling
Biopterin metabolism
Biotin metabolism
Blood group biosynthesis
Butanoate metabolism
C5-branched dibasic acid metabolism
Carnitine shuttle (cytosolic)
Carnitine shuttle (endoplasmic reticular)
Carnitine shuttle (mitochondrial)
Carnitine shuttle (peroxisomal)
Cholesterol biosynthesis 1 (Bloch pathway)
Cholesterol biosynthesis 2
Cholesterol biosynthesis 3 (Kandustch-Russell pathway)
Cholesterol metabolism
Chondroitin / heparan sulfate biosynthesis
Chondroitin sulfate degradation
Cysteine and methionine metabolism
Drug metabolism
Eicosanoid metabolism
Estrogen metabolism
Ether lipid metabolism
Fatty acid activation (cytosolic)
Fatty acid activation (endoplasmic reticular)
Fatty acid biosynthesis
Fatty acid biosynthesis (even-chain)
Fatty acid biosynthesis (odd-chain)
Fatty acid biosynthesis (unsaturated)
Fatty acid degradation
Fatty acid desaturation (even-chain)
Fatty acid desaturation (odd-chain)
Fatty acid elongation (even-chain)
Fatty acid elongation (odd-chain)
Fatty acid metabolism
Fatty acid oxidation
Folate metabolism
Formation and hydrolysis of cholesterol esters
Fructose and mannose metabolism
Galactose metabolism
Glucocorticoid biosynthesis
Glutathione metabolism
Glycerolipid metabolism
Glycerophospholipid metabolism
Glycine; serine and threonine metabolism
Glycolysis / Gluconeogenesis
Glycosphingolipid biosynthesis-ganglio series
Glycosphingolipid biosynthesis-globo series
Glycosphingolipid biosynthesis-lacto and neolacto series
Glycosphingolipid metabolism
Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
Glyoxylate and dicarboxylate metabolism
Heme degradation
Heparan sulfate degradation
Histidine metabolism
Inositol phosphate metabolism
Insect hormone biosynthesis
Isolated
Keratan sulfate biosynthesis
Keratan sulfate degradation
Leukotriene metabolism
Linoleate metabolism
Lipoic acid metabolism
Lysine metabolism
Metabolism of other amino acids
Miscellaneous
N-glycan metabolism
Nicotinate and nicotinamide metabolism
Nucleotide metabolism
O-glycan metabolism
Octane oxidation
Omega-3 fatty acid metabolism
Omega-6 fatty acid metabolism
Oxidative phosphorylation
Pantothenate and CoA metabolism
Pentose and glucuronate interconversions
Pentose phosphate pathway
Phenylalanine metabolism
Phenylalanine; tyrosine and tryptophan biosynthesis
Phosphatidylinositol phosphate metabolism
Pool reactions
Porphyrin metabolism
Propanoate metabolism
Prostaglandin biosynthesis
Protein assembly
Protein degradation
Protein modification
Purine metabolism
Pyrimidine metabolism
Pyruvate metabolism
Retinol metabolism
Riboflavin metabolism
ROS detoxification
Serotonin and melatonin biosynthesis
Sphingolipid metabolism
Starch and sucrose metabolism
Steroid metabolism
Sulfur metabolism
Terpenoid backbone biosynthesis
Thiamine metabolism
Toluene degradation
Transport reactions
Tricarboxylic acid cycle and glyoxylate/dicarboxylate metabolism
Tryptophan metabolism
Tyrosine metabolism
Ubiquinone and other terpenoid-quinone biosynthesis
Ubiquinone synthesis
Valine; leucine; and isoleucine metabolism
Vitamin A metabolism
Vitamin B12 metabolism
Vitamin B2 metabolism
Vitamin B6 metabolism
Vitamin C metabolism
Vitamin D metabolism
Vitamin E metabolism
Xenobiotics metabolism
ipTM
0-0.2
0.2-0.4
0.4-0.6
0.6-0.8
0.8-1
Category
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Category
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Category
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Category
Evidence at protein level
Evidence at transcript level
No human protein/transcript evidence
Validation
Supported
Approved
Uncertain
Validation
Enhanced - Capture
Enhanced - Genetic
Enhanced - Independent
Enhanced - Orthogonal
Enhanced - Recombinant
Supported
Approved
Uncertain
Validation
Enhanced - Independent
Enhanced - Orthogonal
Supported
Approved
Uncertain
Validation
Enhanced - Genetic
Enhanced - Independent
Enhanced - Recombinant
Supported
Approved
Uncertain
Antibodies
Yes
No
Data type
Tissue - Immunohistochemistry
Tissue - GTEx transcriptomics
Tissue - FANTOM transcriptomics
Tissue - Expression clustering
Brain
Brain - Expression clustering
Single cell - Expression clustering
Immune cell - Expression clustering
Subcellular
Cancer - Immunohistochemistry
Cancer - Mass spectrometry
Blood - conc. immunoassay
Blood - conc. mass spectrometry
Blood - Olink HT
Blood - Olink 1536
Blood - SomaScan
Blood - ProteomEdge
Blood - Targeted proteomics
Cell line - Mass spectrometry
Cell line - Expression clustering
Structure
Interaction
Metabolic
Column
Gene
Position
Tissue specific score
Prognostic
Reliability (IF)
Reliability (IH)
Add
Cancel
Interaction
Data
Interaction methods
Protein interaction data
Interaction protein pairs for genes with consensus interaction data
interaction_consensus.tsv.zip
The Human Protein Atlas project is funded
