Immune cell methods

Immune cell summary

Table 1. The expression profiles for the different cell lineages are presented including the classification based on cell lineage specificity

Cell lineage	No of cell types analyzed	No of cell lineage enriched genes	No of cell lineage group enriched genes	No of cell lineage enhanced genes	Total number of cell lineage elevated genes	No of elevated genes with highest expression in blood or lymphoid tissues	Number of cell lineage enriched genes with highest expression in blood or lymphoid tissues
B-cells	2	301	280	6	587	230	154
T-cells	7	460	445	15	920	270	167
NK-cells	1	65	276	1	342	88	10
Monocytes	3	132	620	6	758	105	14
Granulocytes	3	1007	640	15	1662	133	59
Dendritic cells	2	232	582	5	819	112	16

Table 2. The expression profiles for the 18 individual cell types are also presented including the classification based on cell type specificity

Cell type	Cell lineage	No of cell type enriched genes	No of cell type group enriched genes	No of cell type enhanced genes	Total number of cell type elevated genes	No of elevated genes with highest expression in blood or lymphoid tissues	Number of cell type enriched genes with highest expression in blood or lymphoid tissues
Memory B-cell	B-cells	23	367	95	485	210	7
Naive B-cell	B-cells	20	367	114	501	205	5
Myeloid DC	Dendritic cells	28	263	82	373	62	4
Plasmacytoid DC	Dendritic cells	186	177	198	561	69	10
Basophil	Granulocytes	260	269	398	927	51	6
Eosinophil	Granulocytes	74	289	209	572	56	3
Neutrophil	Granulocytes	235	330	469	1034	111	26
Classical monocyte	Monocytes	10	285	80	375	56	0
Intermediate monocyte	Monocytes	1	300	80	381	69	1
Non-classical monocyte	Monocytes	24	272	157	453	65	0
NK-cell	NK-cells	65	151	111	327	69	10
GdT-cell	T-cells	13	141	74	228	73	5
MAIT T-cell	T-cells	27	154	63	244	83	3
Memory CD4 T-cell	T-cells	2	221	25	248	119	0
Memory CD8 T-cell	T-cells	0	230	18	248	123	0
Naive CD4 T-cell	T-cells	1	204	84	289	122	0
Naive CD8 T-cell	T-cells	8	241	29	278	120	0
T-reg	T-cells	36	223	172	431	184	8