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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:36.8 nTPM
HPA Brain:101.0 nTPM
GTEx:36.8 nTPM
FANTOM5:75.4 Scaled Tags Per Million
Pig:63.5 nTPM
Mouse:58.3 nTPM
Allen mouse:7.5 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

101.0
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 88.6
2666 Male, age 74, left hemisphere 118.6
2828 Female, age 72, unknown 108.2
2586 Male, age 75, left hemisphere 107.9
1827 Male, age 72, unknown 99.2
2219 Male, age 76, both hemispheres 89.5
1870 Female, age 42, unknown 76.2
1833 Male, age 53, unknown 75.2
2411 Female, age 72, unknown 74.0
2019 Male, age 18, unknown 71.6
1830 Male, age 51, unknown 65.5
Dorsal raphe nucleus
nTPM: 86.7
2047 Male, age 72, unknown 98.5
2298 Female, age 72, unknown 90.9
1828 Male, age 53, unknown 83.1
2016 Female, age 72, unknown 81.6
2750 Male, age 76, both hemispheres 79.2
Inferior colliculus
nTPM: 75.9
2849 Male, age 72, unknown 79.1
2097 Female, age 72, unknown 76.0
1848 Female, age 42, unknown 74.6
1890 Male, age 53, unknown 74.1
Median raphe nucleus
nTPM: 85.7
2220 Male, age 76, midline 85.7
Periaquaductal grey, anterior
nTPM: 96.9
1795 Male, age 51, unknown 107.2
1947 Male, age 18, unknown 97.2
2502 Female, age 75, unknown 86.3
Periaquaductal grey, dorsal
nTPM: 85.2
1840 Male, age 53, unknown 101.6
1831 Male, age 72, unknown 85.9
2464 Female, age 72, unknown 80.4
2850 Male, age 76, both hemispheres 73.1
Periaquaductal grey, lateral
nTPM: 75.5
2053 Male, age 18, unknown 88.7
2140 Male, age 76, both hemispheres 74.7
2272 Male, age 74, both hemispheres 63.2
Pretectal area
nTPM: 91.1
1816 Male, age 51, unknown 128.0
1944 Female, age 72, unknown 113.6
1815 Male, age 53, unknown 103.9
1817 Female, age 42, unknown 102.2
2007 Male, age 72, unknown 88.7
2825 Male, age 18, unknown 88.6
2407 Male, age 75, both hemispheres 87.5
2667 Female, age 75, unknown 82.1
2224 Female, age 72, unknown 77.5
2316 Male, age 76, right hemisphere 68.2
2273 Male, age 74, both hemispheres 61.7
Red nucleus
nTPM: 69.7
2725 Female, age 75, unknown 89.8
2584 Male, age 75, left hemisphere 88.7
2588 Male, age 74, left hemisphere 75.1
1821 Female, age 72, unknown 70.7
1954 Female, age 42, unknown 67.3
2823 Male, age 76, right hemisphere 67.3
2785 Male, age 18, unknown 67.0
2503 Female, age 72, unknown 66.8
2769 Male, age 72, unknown 62.7
2227 Male, age 72, unknown 61.8
1904 Male, age 53, unknown 61.4
1865 Male, age 51, unknown 57.8
Substantia nigra
nTPM: 101.0
1916 Female, age 42, unknown 129.4
2665 Male, age 74, both hemispheres 116.8
1851 Male, age 51, unknown 104.1
2241 Male, age 72, unknown 104.1
2583 Male, age 75, right hemisphere 102.7
2590 Female, age 75, unknown 94.0
2699 Male, age 18, unknown 93.8
1889 Female, age 72, unknown 89.1
2409 Female, age 72, unknown 88.0
1941 Male, age 53, unknown 87.6
Superior colliculus
nTPM: 89.2
2664 Male, age 75, both hemispheres 115.6
2087 Female, age 72, unknown 104.8
1796 Male, age 53, unknown 100.3
2261 Male, age 18, unknown 99.2
2668 Female, age 75, unknown 87.8
2587 Male, age 74, left hemisphere 81.4
1839 Male, age 51, unknown 80.5
1913 Female, age 42, unknown 77.2
1995 Male, age 72, unknown 76.2
1895 Male, age 76, right hemisphere 69.0
Ventral tegmental area
nTPM: 88.1
2218 Male, age 76, both hemispheres 96.8
2410 Female, age 72, unknown 95.4
1915 Female, age 42, unknown 92.4
1942 Male, age 51, unknown 91.3
2021 Male, age 53, unknown 86.9
2223 Female, age 72, unknown 65.8

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

36.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 36.8
Samples: 139

Max nTPM: 56.1
Min nTPM: 16.1
Std nTPM: 9.0
Median nTPM: 37.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 56.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 55.3
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 55.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 54.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 54.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 53.3
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 53.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 52.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 52.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 51.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 50.7
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 50.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 49.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 48.8
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 48.0
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 47.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 47.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 47.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 47.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 46.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 46.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 46.5
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 46.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 45.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 45.0
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 44.6
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 44.5
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 44.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 44.5
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 44.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 44.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 44.3
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 43.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 43.4
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 42.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 42.8
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 42.7
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 42.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 42.2
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 42.1
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 42.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 42.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 41.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 41.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 40.9
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 40.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 40.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 40.6
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 40.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 40.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 39.8
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 39.8
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 39.5
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 39.4
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 39.2
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 39.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 38.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 38.5
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 38.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 38.4
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 38.3
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 38.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 38.0
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 38.0
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 37.9
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 37.7
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 37.7
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 37.3
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 37.3
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 37.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 37.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 36.5
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 36.0
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 36.0
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 35.9
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 35.9
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 35.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 35.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 35.4
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 35.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 35.0
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 35.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 34.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 34.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 34.7
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 34.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 34.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 34.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 34.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 34.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 33.6
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 33.2
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 33.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 32.9
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 32.5
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 32.2
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 32.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 31.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 31.7
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 31.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 31.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 31.1
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 30.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 30.7
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 30.4
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 30.4
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 30.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 30.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 30.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 29.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 28.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 28.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 28.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 27.9
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 27.5
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 26.6
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 26.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 26.5
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 26.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 25.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 25.7
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 25.4
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 25.3
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 25.1
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 24.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 24.0
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 23.9
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 23.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 23.8
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 22.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 22.6
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 21.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 21.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 21.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 21.1
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 19.4
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 18.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 18.2
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 16.1
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

75.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 75.4
FF:10158-103A5 76 years, female 75.4

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

63.5
Pig sample Sample description nTPM
Substantia nigra
nTPM: 60.7
Samples: 4

Max nTPM: 69.3
Min nTPM: 48.9
Sample A Female 69.3
Sample B Female 56.3
Sample C Male 68.3
Sample D Male 48.9
Midbrain
nTPM: 63.6
Samples: 4

Max nTPM: 74.2
Min nTPM: 53.9
Sample A Female 59.4
Sample B Female 53.9
Sample C Male 74.2
Sample D Male 66.7
Periaqueductal gray
nTPM: 55.2
Samples: 3

Max nTPM: 65.6
Min nTPM: 47.6
Sample B Female 52.5
Sample C Male 65.6
Sample D Male 47.6
Superior colliculi
nTPM: 59.7
Samples: 4

Max nTPM: 64.5
Min nTPM: 54.4
Sample A Female 64.5
Sample B Female 59.7
Sample C Male 54.4
Sample D Male 60.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

58.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 58.3
Samples: 4

Max nTPM: 59.8
Min nTPM: 55.1
Sample A Male 55.1
Sample B Male 59.8
Sample C Female 59.4
Sample D Female 58.7

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

7.5
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 7.5
512991 Antisense, RP_040809_02_F09, Mouse strain C57BL/6J (56 days, male) 10.8
81599648 Antisense, RP_071212_04_F09, Mouse strain C57BL/6J (56 days, male) 4.1

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