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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
85.8
nTPM
HPA:
22.0
nTPM
GTEx:
85.8
nTPM
FANTOM5:
51.7
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA041708
Antibody HPA046765
Cholangiocytes
Medium
Medium
Hepatocytes
High
Medium
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
22.0
Female, age 60
Liver sample 21 nTPM: 59.2
Male, age 54
Liver sample 23 nTPM: 40.8
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 41.2
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 1.5
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 4.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 5.9
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 8.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 27.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 14.6
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 17.3
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
85.8
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 85.8
Samples: 226
Max nTPM: 191.2
Min nTPM: 46.6
Std nTPM: 23.3
Median nTPM: 80.5
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
191.2
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
189.2
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
182.3
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
162.2
GTEX-12696-0826-SM-5EGGE
60-69 years, male
146.6
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
146.5
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
145.7
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
145.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
143.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
139.5
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
134.3
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
131.6
GTEX-14PJO-1726-SM-68719
60-69 years, male
129.0
GTEX-S32W-1926-SM-4AD63
50-59 years, female
128.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
124.2
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
123.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
122.7
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
122.0
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
119.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
116.7
GTEX-14XAO-0226-SM-68728
60-69 years, female
115.6
GTEX-QEL4-1226-SM-447A4
50-59 years, male
113.1
GTEX-REY6-1226-SM-48FDR
60-69 years, male
112.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
111.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
110.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
110.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
109.8
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
108.3
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
107.7
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
107.4
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
107.1
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
106.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
105.0
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
104.5
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
103.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
103.5
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
103.3
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
102.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
102.4
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
101.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
101.4
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
101.1
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
100.5
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
100.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
99.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
99.4
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
99.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
99.1
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
98.6
GTEX-P78B-1326-SM-3P611
40-49 years, female
98.0
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
97.8
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
97.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
97.4
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
97.3
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
96.4
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
95.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
94.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
94.5
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
94.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
93.9
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
93.2
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
92.3
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
92.2
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
92.0
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
91.9
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
91.2
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
91.0
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
90.8
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
90.6
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
90.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
90.2
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
90.2
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
89.9
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
89.1
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
89.0
GTEX-O5YV-0726-SM-EV798
60-69 years, female
88.9
GTEX-RU72-1426-SM-46MUF
50-59 years, female
88.7
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
88.5
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
87.6
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
87.6
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
87.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
87.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
86.9
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
86.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
86.3
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
86.1
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
86.1
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
86.0
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
85.9
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
85.7
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
85.6
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
85.6
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
85.5
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
85.4
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
84.8
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
84.7
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
84.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
84.1
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
84.0
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
83.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
83.7
GTEX-14JG1-1626-SM-664NH
40-49 years, male
83.6
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
83.5
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
83.4
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
83.3
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
83.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
82.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
82.2
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
82.1
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
81.9
GTEX-13113-1326-SM-5GCOI
60-69 years, female
81.6
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
80.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
80.6
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
80.5
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
80.4
GTEX-QESD-2026-SM-447BI
20-29 years, male
80.4
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
80.3
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
80.2
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
80.0
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
79.8
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
79.6
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
79.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
79.4
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
79.3
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
79.3
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
79.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
78.6
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
78.4
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
78.3
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
77.8
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
77.7
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
77.6
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
77.4
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
77.4
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
77.2
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
76.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
76.5
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
76.3
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
76.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
75.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
75.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
75.3
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
75.0
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
74.6
GTEX-18A66-2026-SM-7189C
60-69 years, male
74.5
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
74.5
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
74.4
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
74.3
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
74.2
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
73.8
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
73.4
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
72.8
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
72.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
72.7
GTEX-Q734-0326-SM-48U15
40-49 years, female
72.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
72.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
72.4
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
72.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
72.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
71.8
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
71.7
GTEX-144GL-1426-SM-79OMA
50-59 years, male
71.7
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
71.4
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
71.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
71.2
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
70.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
70.8
GTEX-14PHX-0526-SM-664NW
50-59 years, male
70.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
70.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
70.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
70.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
70.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
70.1
GTEX-14E7W-1526-SM-6871X
70-79 years, male
70.0
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
69.6
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
69.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
69.4
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
69.3
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
69.2
GTEX-X261-1726-SM-4PQYT
50-59 years, male
69.2
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
68.4
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
68.4
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
68.4
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
68.2
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
68.0
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
67.3
GTEX-1399T-0826-SM-5IFES
60-69 years, male
67.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
67.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
67.1
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
66.9
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
66.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
66.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
65.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
65.9
GTEX-17F96-1226-SM-79OK2
70-79 years, male
65.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
65.5
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
65.3
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
65.3
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
64.7
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
64.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
64.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
63.9
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
63.4
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
63.2
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
63.2
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
63.1
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
63.1
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
63.0
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
62.4
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
62.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
62.0
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
61.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
60.5
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
60.2
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
60.0
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
59.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
58.6
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
57.4
GTEX-1B933-1226-SM-731DW
50-59 years, female
57.1
GTEX-17HHE-0126-SM-79398
50-59 years, male
56.3
GTEX-18A7A-1526-SM-72D69
50-59 years, female
56.1
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
54.4
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
51.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
49.5
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
46.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
46.6
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
