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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
65.6
nTPM
HPA:
65.6
nTPM
GTEx:
58.3
nTPM
FANTOM5:
123.1
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA040466
Cholangiocytes
Medium
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
65.6
Female, age 60
Liver sample 21 nTPM: 26.3
Male, age 54
Liver sample 23 nTPM: 72.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 35.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 78.9
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 68.6
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 96
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 43.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 47.6
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 105.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 81.9
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
58.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 58.3
Samples: 226
Max nTPM: 189.4
Min nTPM: 15.3
Std nTPM: 29.5
Median nTPM: 52.0
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
189.4
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
144.1
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
142.9
GTEX-17F96-1226-SM-79OK2
70-79 years, male
142.4
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
137.0
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
131.7
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
127.6
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
125.6
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
124.5
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
121.3
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
120.3
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
116.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
115.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
115.1
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
114.2
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
113.3
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
111.8
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
111.6
GTEX-17HHE-0126-SM-79398
50-59 years, male
109.7
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
109.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
106.7
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
106.6
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
101.7
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
99.2
GTEX-R53T-0326-SM-48FEC
50-59 years, female
98.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
98.3
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
97.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
93.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
93.7
GTEX-14PHX-0526-SM-664NW
50-59 years, male
93.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
92.5
GTEX-18465-1626-SM-7LG6N
50-59 years, male
89.1
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
88.5
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
88.0
GTEX-18A7A-1526-SM-72D69
50-59 years, female
87.0
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
85.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
84.3
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
83.7
GTEX-QESD-2026-SM-447BI
20-29 years, male
83.6
GTEX-14JG1-1626-SM-664NH
40-49 years, male
82.9
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
82.4
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
81.8
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
81.4
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
79.9
GTEX-RN64-1826-SM-48FDV
50-59 years, male
79.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
79.2
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
79.1
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
78.0
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
76.2
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
75.8
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
74.7
GTEX-13113-1326-SM-5GCOI
60-69 years, female
73.8
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
73.5
GTEX-X261-1726-SM-4PQYT
50-59 years, male
73.0
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
72.2
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
70.8
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
70.5
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
70.3
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
69.7
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
69.0
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
69.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
68.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
68.9
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
67.6
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
67.3
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
67.1
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
66.9
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
66.8
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
66.7
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
66.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
66.1
GTEX-11ZUS-2526-SM-59872
30-39 years, male
66.0
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
65.2
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
65.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
65.0
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
64.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
64.0
GTEX-1B933-1226-SM-731DW
50-59 years, female
64.0
GTEX-13112-1426-SM-5EGH8
50-59 years, male
63.7
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
63.5
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
63.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
61.7
GTEX-REY6-1226-SM-48FDR
60-69 years, male
61.6
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
61.5
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
60.6
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
59.6
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
59.4
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
59.2
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
59.2
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
58.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
58.7
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
58.7
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
58.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
58.3
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
58.0
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
57.5
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
57.2
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
56.8
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
56.8
GTEX-YECK-1926-SM-4W21H
60-69 years, male
56.7
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
56.6
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
55.3
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
55.3
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
54.4
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
53.9
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
53.4
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
53.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
52.8
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
52.8
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
52.6
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
52.4
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
52.2
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
52.1
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
51.9
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
51.4
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
51.3
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
51.2
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
51.0
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
50.8
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
50.7
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
50.6
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
50.3
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
50.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
50.1
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
48.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
48.5
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
48.1
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
48.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
48.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
47.6
GTEX-18A66-2026-SM-7189C
60-69 years, male
47.3
GTEX-14PJO-1726-SM-68719
60-69 years, male
46.5
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
46.0
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
46.0
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
45.9
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
45.7
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
45.1
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
44.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
44.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
44.8
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
44.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
43.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
43.6
GTEX-14E7W-1526-SM-6871X
70-79 years, male
43.5
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
43.0
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
42.8
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
42.6
GTEX-P78B-1326-SM-3P611
40-49 years, female
42.4
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
41.7
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
41.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
41.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
41.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
41.3
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
41.3
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
41.2
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
41.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
40.9
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
40.8
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
40.5
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
39.6
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
39.6
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
39.3
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
39.0
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
39.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
38.9
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
38.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
38.4
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
38.2
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
38.1
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
38.0
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
37.3
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
37.2
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
36.7
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
36.4
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
36.0
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
36.0
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
35.9
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
35.9
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
35.8
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
35.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
35.7
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
35.4
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
35.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
33.4
GTEX-1B932-1426-SM-793AN
40-49 years, female
33.2
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
32.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
32.3
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
31.9
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
31.8
GTEX-12696-0826-SM-5EGGE
60-69 years, male
31.3
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
30.8
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
30.4
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
30.3
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
30.1
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
30.0
GTEX-14XAO-0226-SM-68728
60-69 years, female
29.8
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
29.2
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
28.9
GTEX-1399T-0826-SM-5IFES
60-69 years, male
28.9
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
28.8
GTEX-O5YV-0726-SM-EV798
60-69 years, female
28.5
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
28.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
27.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
26.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
26.0
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
25.6
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
25.0
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
25.0
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
24.8
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
24.4
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
23.6
GTEX-S32W-1926-SM-4AD63
50-59 years, female
22.1
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
21.8
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
21.8
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
20.7
GTEX-11GSP-0626-SM-5986T
60-69 years, female
20.6
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
20.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
20.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
20.1
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
18.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
17.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
16.9
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
16.7
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
15.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
15.7
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
15.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
