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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Medium
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
123.8
nTPM
HPA:
123.8
nTPM
GTEx:
122.5
nTPM
FANTOM5:
136.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA031531
Cholangiocytes
Medium
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
123.8
Female, age 60
Liver sample 21 nTPM: 112.2
Male, age 54
Liver sample 23 nTPM: 106
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 117.8
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 111.8
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 145.4
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 117
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 129.1
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 145.1
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 114.8
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 138.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
122.5
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 122.5
Samples: 226
Max nTPM: 238.3
Min nTPM: 61.4
Std nTPM: 29.6
Median nTPM: 121.7
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
238.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
198.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
194.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
193.0
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
187.8
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
187.2
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
182.3
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
181.9
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
178.7
GTEX-S32W-1926-SM-4AD63
50-59 years, female
174.8
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
174.1
GTEX-14PHX-0526-SM-664NW
50-59 years, male
173.7
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
173.6
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
165.6
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
165.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
163.0
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
162.4
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
161.5
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
160.2
GTEX-14XAO-0226-SM-68728
60-69 years, female
159.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
158.2
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
157.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
157.8
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
157.5
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
156.9
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
155.8
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
155.8
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
155.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
154.8
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
154.6
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
154.5
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
153.9
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
152.8
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
152.6
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
151.1
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
150.7
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
150.6
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
150.5
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
149.7
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
149.0
GTEX-12696-0826-SM-5EGGE
60-69 years, male
148.1
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
147.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
147.8
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
147.8
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
147.3
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
146.7
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
146.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
146.5
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
146.1
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
146.0
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
145.4
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
145.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
145.0
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
144.4
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
144.0
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
143.7
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
143.0
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
142.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
142.8
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
142.2
GTEX-REY6-1226-SM-48FDR
60-69 years, male
141.6
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
141.0
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
140.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
140.8
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
139.6
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
139.5
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
139.4
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
139.4
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
139.3
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
139.2
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
138.7
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
138.1
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
137.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
137.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
137.5
GTEX-13113-1326-SM-5GCOI
60-69 years, female
137.1
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
136.7
GTEX-17HHE-0126-SM-79398
50-59 years, male
136.4
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
136.3
GTEX-P78B-1326-SM-3P611
40-49 years, female
136.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
136.0
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
135.9
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
135.8
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
135.1
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
134.4
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
134.0
GTEX-14E7W-1526-SM-6871X
70-79 years, male
133.3
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
133.3
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
132.4
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
131.7
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
131.6
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
131.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
131.1
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
131.0
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
130.7
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
129.8
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
129.6
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
129.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
128.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
127.7
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
126.2
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
126.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
126.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
125.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
125.2
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
125.1
GTEX-R53T-0326-SM-48FEC
50-59 years, female
125.0
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
124.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
124.2
GTEX-1B932-1426-SM-793AN
40-49 years, female
123.0
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
122.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
122.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
121.7
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
121.7
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
121.3
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
120.9
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
120.0
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
120.0
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
119.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
119.6
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
117.9
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
117.8
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
117.4
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
117.3
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
117.3
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
116.2
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
115.5
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
115.2
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
115.1
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
115.0
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
114.4
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
113.2
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
113.2
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
113.0
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
112.6
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
112.3
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
112.1
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
112.0
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
111.8
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
111.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
111.4
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
110.7
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
109.5
GTEX-1399T-0826-SM-5IFES
60-69 years, male
109.1
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
108.9
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
108.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
108.1
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
107.9
GTEX-17F96-1226-SM-79OK2
70-79 years, male
107.2
GTEX-S33H-1626-SM-4AD68
30-39 years, male
107.1
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
106.9
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
106.7
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
106.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
105.4
GTEX-18A7A-1526-SM-72D69
50-59 years, female
105.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
105.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
104.8
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
104.7
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
103.7
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
102.3
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
102.1
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
101.5
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
101.3
GTEX-11ZUS-2526-SM-59872
30-39 years, male
100.1
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
99.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
99.3
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
99.0
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
98.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
98.8
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
97.7
GTEX-O5YV-0726-SM-EV798
60-69 years, female
97.5
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
97.4
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
96.7
GTEX-13112-1426-SM-5EGH8
50-59 years, male
96.7
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
96.5
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
95.9
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
95.7
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
95.7
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
95.6
GTEX-18465-1626-SM-7LG6N
50-59 years, male
95.4
GTEX-X261-1726-SM-4PQYT
50-59 years, male
94.9
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
94.7
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
94.4
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
94.1
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
93.8
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
93.4
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
93.3
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
93.2
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
93.1
GTEX-11GSP-0626-SM-5986T
60-69 years, female
92.8
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
92.8
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
92.8
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
92.0
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
91.5
GTEX-YECK-1926-SM-4W21H
60-69 years, male
91.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
91.1
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
89.2
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
89.0
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
88.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
88.1
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
87.5
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
86.5
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
86.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
85.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
85.9
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
85.2
GTEX-144GL-1426-SM-79OMA
50-59 years, male
85.1
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
84.0
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
82.4
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
81.2
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
80.9
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
80.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
80.1
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
79.2
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
78.4
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
78.3
GTEX-1B933-1226-SM-731DW
50-59 years, female
75.8
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
74.9
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
72.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
72.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
72.3
GTEX-RN64-1826-SM-48FDV
50-59 years, male
67.1
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
66.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
65.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
62.8
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
61.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
