MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:14.0 nTPM
HPA Brain:42.1 nTPM
GTEx:14.0 nTPM
FANTOM5:8.9 Scaled Tags Per Million
Pig:38.8 nTPM
Mouse:32.4 nTPM
Allen mouse:4.6 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 42.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 23.2
2219 Male, age 76, both hemispheres 44.4
2828 Female, age 72, unknown 30.6
2019 Male, age 18, unknown 28.9
2666 Male, age 74, left hemisphere 24.0
1827 Male, age 72, unknown 22.4
2586 Male, age 75, left hemisphere 21.8
2411 Female, age 72, unknown 17.6
1870 Female, age 42, unknown 15.8
1833 Male, age 53, unknown 14.5
1830 Male, age 51, unknown 11.8
Dorsal raphe nucleus
nTPM: 13.3
2298 Female, age 72, unknown 16.7
2750 Male, age 76, both hemispheres 14.8
1828 Male, age 53, unknown 12.1
2016 Female, age 72, unknown 11.9
2047 Male, age 72, unknown 11.0
Inferior colliculus
nTPM: 9.6
1848 Female, age 42, unknown 11.2
1890 Male, age 53, unknown 10.2
2849 Male, age 72, unknown 9.5
2097 Female, age 72, unknown 7.4
Median raphe nucleus
nTPM: 22.5
2220 Male, age 76, midline 22.5
Periaquaductal grey, anterior
nTPM: 28.8
2502 Female, age 75, unknown 43.3
1795 Male, age 51, unknown 26.8
1947 Male, age 18, unknown 16.3
Periaquaductal grey, dorsal
nTPM: 14.6
1831 Male, age 72, unknown 17.7
1840 Male, age 53, unknown 16.9
2464 Female, age 72, unknown 13.6
2850 Male, age 76, both hemispheres 10.2
Periaquaductal grey, lateral
nTPM: 11.9
2053 Male, age 18, unknown 13.2
2140 Male, age 76, both hemispheres 12.9
2272 Male, age 74, both hemispheres 9.7
Pretectal area
nTPM: 34.6
1944 Female, age 72, unknown 61.7
1816 Male, age 51, unknown 58.7
2667 Female, age 75, unknown 55.1
1815 Male, age 53, unknown 49.3
1817 Female, age 42, unknown 45.8
2007 Male, age 72, unknown 45.6
2224 Female, age 72, unknown 18.0
2273 Male, age 74, both hemispheres 15.2
2825 Male, age 18, unknown 12.1
2316 Male, age 76, right hemisphere 10.2
2407 Male, age 75, both hemispheres 8.4
Red nucleus
nTPM: 11.9
2785 Male, age 18, unknown 25.5
2584 Male, age 75, left hemisphere 19.1
2588 Male, age 74, left hemisphere 16.5
2725 Female, age 75, unknown 11.9
1904 Male, age 53, unknown 11.0
1821 Female, age 72, unknown 9.2
2769 Male, age 72, unknown 8.7
1954 Female, age 42, unknown 8.5
1865 Male, age 51, unknown 8.4
2227 Male, age 72, unknown 8.2
2503 Female, age 72, unknown 8.0
2823 Male, age 76, right hemisphere 7.3
Substantia nigra
nTPM: 42.1
2665 Male, age 74, both hemispheres 91.7
1916 Female, age 42, unknown 62.2
1851 Male, age 51, unknown 53.9
1889 Female, age 72, unknown 40.3
1941 Male, age 53, unknown 37.4
2409 Female, age 72, unknown 35.3
2241 Male, age 72, unknown 35.2
2699 Male, age 18, unknown 31.2
2583 Male, age 75, right hemisphere 21.1
2590 Female, age 75, unknown 13.1
Superior colliculus
nTPM: 22.7
2087 Female, age 72, unknown 50.7
1796 Male, age 53, unknown 29.9
2261 Male, age 18, unknown 26.9
1913 Female, age 42, unknown 24.4
1995 Male, age 72, unknown 20.3
2587 Male, age 74, left hemisphere 18.4
2668 Female, age 75, unknown 16.5
2664 Male, age 75, both hemispheres 14.4
1895 Male, age 76, right hemisphere 14.1
1839 Male, age 51, unknown 11.7
Ventral tegmental area
nTPM: 34.7
2218 Male, age 76, both hemispheres 57.7
2410 Female, age 72, unknown 47.5
1942 Male, age 51, unknown 38.5
1915 Female, age 42, unknown 38.2
2021 Male, age 53, unknown 14.5
2223 Female, age 72, unknown 11.8

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 14.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 14.0
Samples: 183

Max nTPM: 54.0
Min nTPM: 0.8
Std nTPM: 12.2
Median nTPM: 9.6
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 54.0
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 53.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 48.1
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 46.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 42.4
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 42.4
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 42.0
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 41.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 41.5
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 40.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 39.9
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 8.9
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 8.9
FF:10158-103A5 76 years, female 8.9

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 38.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 16.9
Samples: 4

Max nTPM: 28.2
Min nTPM: 2.5
Sample A Female 25.4
Sample B Female 11.3
Sample C Male 28.2
Sample D Male 2.5
Midbrain
nTPM: 36.5
Samples: 4

Max nTPM: 133.0
Min nTPM: 1.7
Sample A Female 1.7
Sample B Female 9.0
Sample C Male 133.0
Sample D Male 2.3
Periaqueductal gray
nTPM: 4.8
Samples: 3

Max nTPM: 6.6
Min nTPM: 3.6
Sample B Female 6.6
Sample C Male 4.2
Sample D Male 3.6
Superior colliculi
nTPM: 38.8
Samples: 4

Max nTPM: 95.5
Min nTPM: 5.0
Sample A Female 5.0
Sample B Female 25.8
Sample C Male 95.5
Sample D Male 29.0

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 32.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 32.4
Samples: 4

Max nTPM: 39.1
Min nTPM: 26.4
Sample A Male 26.4
Sample B Male 31.5
Sample C Female 39.1
Sample D Female 32.5

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 4.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.6
77454722 Antisense, RP_070129_01_D05, Mouse strain C57BL/6J (56 days, male) 6.1
1174 Antisense, RP_Baylor_102618, Mouse strain C57BL/6J (56 days, male) 3.2
1173 Antisense, RP_Baylor_102618, Mouse strain C57BL/6J (56 days, male) 2.1

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