The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Moderate granular cytoplasmic staining in a highly organized pattern accentuated towards the lumen was seen in glandular cells of gastrointestinal tract. Distinct cytoplasmic staining in a subset of inflammatory cells seen in most tissues including monocytes and macrophages. Lymphoid tissues were also distinctly stained. Remaining tissues were negative.
Staining was observed in macrophages as well as plasma cells in most tissues.
Strong cytoplasmic positivity in monocyte-derived cells, plasma cells and subsets of hematopoietic cells. Remaining cells were negative.
Strong cytoplasmic staining of macrophages in lymphoid tissues, lung, gastrointestinal tract, liver, placenta and in a few other tissues. Strong staining was also observed in a subset of cells in bone marrow. Other cells were negative.
Strong cytoplasmic staining of macrophages in lung and lymphoid tissues. Strong staining also seen in Langerhans cells in skin, Kupffer cells in liver, microglia in CNS and subsets of cells in bone marrow.