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PDCD4
HPA
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  • PDCD4
CELL LINE
ADRENOCORTICAL CANCER BILE DUCT CANCER BLADDER CANCER BONE CANCER BRAIN CANCER BREAST CANCER CERVICAL CANCER COLORECTAL CANCER ESOPHAGEAL CANCER GALLBLADDER CANCER
GASTRIC CANCER HEAD AND NECK CANCER KIDNEY CANCER LEUKEMIA LIVER CANCER LUNG CANCER LYMPHOMA MYELOMA NEUROBLASTOMA NON-CANCEROUS
OVARIAN CANCER PANCREATIC CANCER PROSTATE CANCER RHABDOID SARCOMA SKIN CANCER TESTIS CANCER THYROID CANCER UNCATEGORIZED UTERINE CANCER
Human cell lines
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

PDCD4
Gene descriptioni

Full gene name according to HGNC.

Programmed cell death 4
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Intracellular
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

3
HUMAN PROTEIN ATLAS INFORMATIONi

Summary of RNA expression based on cell line data from the DepMap portal and cell line data generated within the Human Protein Atlas project.

Cell line expression clusteri

The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity.

Breast cancer - Unknown function (mainly)
Cell line specificityi

RNA specificity category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.

Low cancer specificity
Tau specificity scorei

Tau specificity score is a numerical indicator of the specificity of the gene expression across cells or tissues. The value ranges from 0 and 1, where 0 indicates identical expression across all cells/tissue types, while 1 indicates expression in a single cell/tissue type.

0.23
Cell line distributioni

RNA distribution category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.

Detected in all
Protein evidencei

Evidence score for genes based on UniProt protein existence (UniProt evidence); neXtProt protein existence (neXtProt evidence);and a Human Protein Atlas antibody- or RNA based score (HPA evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable.

Evidence at protein level
CELL LINE GROUPSi

This figure is comparatively showing RNA level (nTPM) and Protein level (nRPX) of various cell line groups of this particular gene. It is possible to reorder the Barchart by the levels of RNA expression or the cell line group names.

Cell line categories
Alphabetical
Expression
RNA specificity: Low cancer specificity
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines.The analyzed cell lines are grouped according to cancer type. Detailed information about the groups is revealed by hovering over the corresponding bar in the chart. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cancer cell line group. The size of the circle corresponds to the median Normalized Relative Protein Expression (nRPX) for the cell lines with MS data in each group, the color represents the tissue type to which the cancer belongs with the intensity of the color reflecting the percentage of the cell lines in the group showing expression of the protein according to MS data. A white circle means that the protein was not detected by MS in corresponding cell lines, while no circle means that MS data was not available for the cell lines.

Please refer to the method of this section for more details.

COMMON CELL LINESi

Similar to the cell line group figure above, this figure is relatively comparing RNA level (nTPM) and Protein level (nRPX) of each cell line in the cell line group of this particular gene. It is possible to reorder the Barchart by the levels of RNA expression or the cell line group names.

Alphabetical
Expression
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.


EXPRESSION CLUSTERING & CORRELATIONi

The RNA data was used to cluster genes according to their expression across samples. The resulting clusters have been manually annotated to describe common features in terms of function and specificity. The annotation of the cluster is displayed together with a confidence score of the gene's assignment to the cluster. The confidence is calculated as the fraction of times the gene was assigned to this cluster in repeated calculations and is reported between 0 to 1, where 1 is the highest possible confidence. The clustering results are shown in a UMAP, where the cluster this gene was assigned to is highlighted as a colored area in which most of the cluster genes reside. A table shows the 15 most similar genes in terms of expression profile.

PDCD4 is part of cluster 27 Breast cancer - Unknown function with confidencei

Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore reflects how strongly associated it is to the cluster. A confidence of 1 indicates that the gene was assigned to this cluster in all repeated clusterings.

1
687 genes in cluster
Go to interactive expression cluster page
15 nearest neighbours based on cell line RNA expression
Neighbouri

Gene name according to HGNC.

Descriptioni

Gene description according to HGNC.

Correlationi

Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.

Clusteri

ID of the expression cluster of the neighboring gene.

SHOC2 SHOC2 leucine rich repeat scaffold protein 0.4693 46
SPDEF SAM pointed domain containing ETS transcription factor 0.4414 27
SRARP Steroid receptor associated and regulated protein 0.4334 27
CREB3L4 CAMP responsive element binding protein 3 like 4 0.4279 27
LRRC26 Leucine rich repeat containing 26 0.4270 60
ZNF552 Zinc finger protein 552 0.4148 27
IGHM Immunoglobulin heavy constant mu 0.4134 46
SMIM14 Small integral membrane protein 14 0.4132 46
IQSEC1 IQ motif and Sec7 domain ArfGEF 1 0.4129 55
GPER1 G protein-coupled estrogen receptor 1 0.4112 46
LRSAM1 Leucine rich repeat and sterile alpha motif containing 1 0.4063 43
TMEM210 Transmembrane protein 210 0.4046 60
RAPGEF1 Rap guanine nucleotide exchange factor 1 0.4034 55
ACER1 Alkaline ceramidase 1 0.3933 60
CRACR2B Calcium release activated channel regulator 2B 0.3900 27

CELL LINE DATA
Alphabetical
Expression
Adrenocortical cancer (n=1)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Bile duct cancer (n=7)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Bladder cancer (n=26)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Bone cancer (n=21)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Brain cancer (n=80)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Breast cancer (n=62)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Cervical cancer (n=8)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Colorectal cancer (n=63)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Esophageal cancer (n=27)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Gallbladder cancer (n=1)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Gastric cancer (n=42)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Head and Neck cancer (n=38)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Kidney cancer (n=35)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Leukemia (n=93)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Liver cancer (n=24)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Lung cancer (n=232)


RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Lymphoma (n=76)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Myeloma (n=34)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Neuroblastoma (n=17)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Non-cancerous (n=63)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Ovarian cancer (n=59)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Pancreatic cancer (n=46)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Prostate cancer (n=8)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Rhabdoid (n=14)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Sarcoma (n=15)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Skin cancer (n=62)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Testis cancer (n=1)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Thyroid cancer (n=11)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Uncategorized (n=11)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

Alphabetical
Expression
Uterine cancer (n=29)
RNAi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines. Similar to the cell line groups above, this plot show each individual nTPM of the gene in each cell line. More information and cell line data can be found in the Cell line resource.






Proteini

Protein expression based on the MS proteomics dataset from the Pan-Cancer Atlas project is represented by a circle for each cell line.The size of the circle corresponds to the Normalized Relative Protein Expression (nRPX) value for the cell line and the color represents the tissue type to which the cell line is related. A white circle means that the protein was not detected by MS in the cell line, while no circle means that MS data was not available for the cell line.

Please refer to the method of this section for more details.

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