The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Neuronal cells and squamous epithelia displayed strong nucleolar staining with additional cytoplasmic positivity in renal tubules. Respiratory epithelia, epididymis, fallopian tube, gall bladder, exocrine pancreas, intestine, testis and urothelium were moderately stained. Remaining normal tissues were weakly stained or negative.
Weak to moderate cytoplasmic and/or nucleolar positivity was displayed in most normal tissues. Lung, lymphoid cells, muscle tissues, placenta, breast and prostate were negative.
Most of the normal tissues showed distinct nucleolar positivity. Glial cells, glandular cells in prostate, hepatocytes, heart and smooth muscle myocytes were negative.
Moderate to strong nucleolar staining was observed in most normal tissues. Lung, placenta, endocrine glands, endometrium, lymphoid tissues and mesenchymal cells were negative.
Weak to moderate nucleolar staining was observed in the majority of normal tissues.