The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Breast epithelium and purkinje cells showed strong membranous positivity. Moderate staining was observed in lung macrophages, melanocytes, a subset of renal tubular cells, cells in seminiferus ducts and falopian tube. Remaining normal tissues were in general weakly stained or negative.
A subset of inflammatory cells were distinctly positive in the cytoplasm. Molecular layer of cerebellum and melanocytes were moderately stained. Remaining normal tissues were mainly negative.
Distinct cytoplasmic positivity was observed in subsets of peripheral lymphocytes. Moderate cytoplasmic positivity was observed in melanocytes and chondrocytes. Glandular cells of breast were weakly stained. Remaining normal tissues were negative.
Strong cytoplasmic staining of basket cells in cerebellum, subset of neuronal cells and neuropil in CNS. Strong cytoplasmic and membranous staining was also seen in breast glands and melanocytes in skin. Additional strong staining in a rare subset of immune cells.