MIDBRAIN - Expression summary
Protein expressioni No data
RNA expressioni
Consensus:78.0 nTPM
HPA Brain:57.6 nTPM
GTEx:78.0 nTPM
FANTOM5:71.8 Scaled Tags Per Million
Pig:304.4 nTPM
Mouse:108.2 nTPM
Allen mouse:4.8 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi 57.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 49.0
2019 Male, age 18, unknown 54.2
2411 Female, age 72, unknown 54.2
2666 Male, age 74, left hemisphere 52.2
2828 Female, age 72, unknown 51.0
1870 Female, age 42, unknown 49.6
1827 Male, age 72, unknown 49.5
2586 Male, age 75, left hemisphere 47.8
1833 Male, age 53, unknown 46.1
1830 Male, age 51, unknown 43.2
2219 Male, age 76, both hemispheres 42.0
Dorsal raphe nucleus
nTPM: 47.6
1828 Male, age 53, unknown 51.1
2298 Female, age 72, unknown 50.3
2047 Male, age 72, unknown 47.3
2016 Female, age 72, unknown 44.9
2750 Male, age 76, both hemispheres 44.6
Inferior colliculus
nTPM: 45.5
1890 Male, age 53, unknown 49.4
2097 Female, age 72, unknown 47.2
1848 Female, age 42, unknown 44.2
2849 Male, age 72, unknown 41.1
Median raphe nucleus
nTPM: 44.1
2220 Male, age 76, midline 44.1
Periaquaductal grey, anterior
nTPM: 44.1
2502 Female, age 75, unknown 48.3
1947 Male, age 18, unknown 42.0
1795 Male, age 51, unknown 41.9
Periaquaductal grey, dorsal
nTPM: 42.1
1831 Male, age 72, unknown 45.3
2850 Male, age 76, both hemispheres 42.5
1840 Male, age 53, unknown 40.5
2464 Female, age 72, unknown 40.2
Periaquaductal grey, lateral
nTPM: 42.0
2272 Male, age 74, both hemispheres 45.0
2053 Male, age 18, unknown 43.5
2140 Male, age 76, both hemispheres 37.5
Pretectal area
nTPM: 48.1
1817 Female, age 42, unknown 58.4
2007 Male, age 72, unknown 57.5
1815 Male, age 53, unknown 56.1
1816 Male, age 51, unknown 54.0
1944 Female, age 72, unknown 50.8
2407 Male, age 75, both hemispheres 48.4
2667 Female, age 75, unknown 43.7
2273 Male, age 74, both hemispheres 43.4
2825 Male, age 18, unknown 40.4
2224 Female, age 72, unknown 39.7
2316 Male, age 76, right hemisphere 36.5
Red nucleus
nTPM: 50.1
1865 Male, age 51, unknown 57.3
1821 Female, age 72, unknown 54.5
2785 Male, age 18, unknown 53.5
1904 Male, age 53, unknown 51.2
2584 Male, age 75, left hemisphere 49.2
1954 Female, age 42, unknown 49.0
2823 Male, age 76, right hemisphere 48.8
2725 Female, age 75, unknown 48.7
2588 Male, age 74, left hemisphere 48.6
2503 Female, age 72, unknown 48.5
2769 Male, age 72, unknown 46.1
2227 Male, age 72, unknown 45.6
Substantia nigra
nTPM: 57.6
1851 Male, age 51, unknown 65.8
2665 Male, age 74, both hemispheres 65.1
1916 Female, age 42, unknown 64.0
2699 Male, age 18, unknown 58.0
1889 Female, age 72, unknown 57.2
2241 Male, age 72, unknown 55.9
2409 Female, age 72, unknown 55.4
1941 Male, age 53, unknown 54.7
2590 Female, age 75, unknown 51.6
2583 Male, age 75, right hemisphere 48.1
Superior colliculus
nTPM: 47.7
2668 Female, age 75, unknown 53.7
1913 Female, age 42, unknown 52.7
2587 Male, age 74, left hemisphere 51.3
1796 Male, age 53, unknown 49.0
1995 Male, age 72, unknown 48.6
2087 Female, age 72, unknown 47.7
2261 Male, age 18, unknown 46.8
2664 Male, age 75, both hemispheres 45.2
1895 Male, age 76, right hemisphere 41.1
1839 Male, age 51, unknown 40.5
Ventral tegmental area
nTPM: 50.1
2410 Female, age 72, unknown 63.8
1915 Female, age 42, unknown 55.9
2223 Female, age 72, unknown 48.1
2218 Male, age 76, both hemispheres 48.0
1942 Male, age 51, unknown 45.9
2021 Male, age 53, unknown 39.1

MIDBRAIN - GTEx RNA-seqi
Max subtype nTPMi 78.0
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 78.0
Samples: 183

Max nTPM: 127.1
Min nTPM: 47.4
Std nTPM: 14.6
Median nTPM: 76.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 127.1
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 118.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 113.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 113.1
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 111.7
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 111.6
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 108.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 107.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 106.9
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 106.7
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 106.4
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MIDBRAIN - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 71.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 71.8
FF:10158-103A5 76 years, female 71.8

MIDBRAIN - Pig RNA-seqi
Max subtype nTPMi 304.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 291.4
Samples: 4

Max nTPM: 325.6
Min nTPM: 235.9
Sample A Female 325.6
Sample B Female 306.7
Sample C Male 235.9
Sample D Male 297.2
Midbrain
nTPM: 285.8
Samples: 4

Max nTPM: 416.1
Min nTPM: 210.6
Sample A Female 416.1
Sample B Female 290.0
Sample C Male 226.3
Sample D Male 210.6
Periaqueductal gray
nTPM: 235.5
Samples: 3

Max nTPM: 244.9
Min nTPM: 221.6
Sample B Female 244.9
Sample C Male 221.6
Sample D Male 239.9
Superior colliculi
nTPM: 304.4
Samples: 4

Max nTPM: 357.4
Min nTPM: 247.5
Sample A Female 333.3
Sample B Female 357.4
Sample C Male 247.5
Sample D Male 279.4

MIDBRAIN - Mouse RNA-seqi
Max subtype nTPMi 108.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 108.2
Samples: 4

Max nTPM: 115.0
Min nTPM: 101.5
Sample A Male 106.6
Sample B Male 101.5
Sample C Female 109.8
Sample D Female 115.0

MIDBRAIN - Allen Mouse ISHi
Max subtype Expression energyi 4.8
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 4.8
121097 Antisense, RP_040507_01_A03, Mouse strain C57BL/6J (56 days, male) 6.2
76081939 Antisense, RP_060626_01_B02, Mouse strain C57BL/6J (56 days, male) 4.4
77620333 Antisense, RP_070205_01_B07, Mouse strain C57BL/6J (56 days, male) 3.8
77869814 Antisense, RP_070205_01_B07, Mouse strain C57BL/6J (56 days, male) 0.7

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