The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Erythrocytes, subsets of bone marrow poietic and lymphoid cells showed strong cytoplasmic staining. Distinct positivity was also observed in the intestine, hepatocytes, exocrine pancreas, breast, leydig cells and the adrenal gland. Remaining normal cells were weakly stained or negative.
Red blood cells and a subset of bone marrow poietic cells were strongly stained. Hepatocytes showed distinct cytoplasmic and nuclear positivity while moderate to strong cytoplasmic staining was observed in the superficial cells of the intestine. Remaining normal tissues were negative.
Erythrocytes were distinctly stained. Most of the normal tissues displayed weak to moderate cytoplasmic and membranous positivity. Squamous epithelia, liver, lymphoid and most cells in the CNS were negative.
Erythrocytes were strongly stained. Respiratory epithelia, adrenal gland, squamous epithelia, hepatocytes, urinary bladder, testis, epididymis and myocytes displayed moderate cytoplasmic positivity. Remaining normal tissues were weakly stained or negative.