The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Most normal tissues were negative. Leydig cells in testis and subsets of glial cells in CNS showed moderate to strong cytoplasmic and nuclear immunoreactivity. Subsets of renal tubules, superficial layers in squamous epithelium, myocytes in heart and skeletal muscles displayed moderate cytoplasmic positivity.
Subsets of cells in pancreatic islets and the adrenal gland showed strong cytoplasmic staining while Leydig cells in testis showed moderate staining. The remaining normal tissues were generally negative.
Moderate cytoplasmic positivity was observed in cell in CNS. Paneth cells in intestinal tract and renal tubules displayed strong cytoplasmic positivity. Gastrointestinal tract, testis, respiratory epithelial cells of bronchus, thyroid gland and exocrine pancreas showed weak to moderate staining. Remaining normal cells were negative.