The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Neuronal cells, squamous epithelia, lymphoid tissue, urothelial cells and fallopian tube displayed moderate nucleolar and/or cytoplasmic staining. Gastrointestinal tract, hepatocytes, kidney tubule cells and glandular cells of breast were weakly stained. Remaining normal tissues were mostly negative.
Moderate nucleolar positivity was observed in squamous epithelial cells, hepatocytes, Leydig cells, adrenal and neuronal cells. Exocrine pancreas and skeletal myocytes showed moderate cytoplasmic staining. Remaining normal tissues showed weak nucleolar positivity or were negative.
Most normal tissues showed weak nucleolar staining or were negative. Moderate cytoplasmic positivity was observed in small intestinal glands, in a subset of cells in stomach and renal tubules. Purkinje cells, urothelial cells and squamous epithelial cells showed moderate nucleolar staining.