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TISSUE PRIMARY DATA SALIVARY GLAND Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Salivary gland
Tissue proteome
Salivary gland
Tissue methods
SALIVARY GLAND - Expression summary
Protein expression
Salivary glandi

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

h
m
l
n
Glandular cells: High
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Cytoplasmic staining in serous acini. Additional staining in small ducts.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:25571.3 nTPM
HPA:23962.5 nTPM
GTEx:25571.3 nTPM
FANTOM5:102344.6 Scaled Tags Per Million
SALIVARY GLAND - SINGLE CELL RNA EXPRESSION
Explore single cell type data

SALIVARY GLAND - Multiplex stainingi

Antibody localization in the annotated cell types/states/structures of the current human tissue is reported as main/additional locations, percent overlap between the antibody and cell type/state/structure-specific markers, and, when applicable also subcellular localization. The scores are based on multiplex immunohistochemistry profiling in selected tissues.

Main locations are characterized by a high overlap between the antibody and the cell type/state-specific marker combined with strong antibody signal intensity, while additional locations are characterized by lower overlap and weaker antibody signal intensity.

The antibody of interest is reported in green, while cell types/states/structures are reported in various other colors, and DAPI (marks nucleus) is reported in blue. Colors can be toggled on and off by clicking on the name of the cell type/state of interest, “Antibody” or “DAPI”. To toggle between the different tissue samples, click on the miniature images at the right bottom corner of the main image. The miniature images appear upon hovering the mouse over that area.

- Antibody HPA006411
Main location Serous acini
Small ducts
Antibody overlap75%-51%
LocationCytoplasm
No antibody overlap
No antibody overlap
No antibody overlap
Antibody overlap75%-51%
LocationCytoplasm

SALIVARY GLAND - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

Antibody HPA006411
Glandular cells High


SALIVARY GLAND - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Average nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23962.5
overview
Female, age 68
Salivary gland sample 216
nTPM: 40089.9
Cell types%
Glandular cells:
45

Ductal cells:
25

Adipocytes:
5

Other cell types:
25

overview
Male, age 60
Salivary gland sample 217
nTPM: 31326.8
Cell types%
Glandular cells:
55

Ductal cells:
20

Adipocytes:
5

Endothelial cells:
5

Other cell types:
15

overview
Female, age 21
Salivary gland sample 218
nTPM: 470.8
Cell types%
Glandular cells:
55

Ductal cells:
15

Adipocytes:
5

Endothelial cells:
5

Other cell types:
20


SALIVARY GLAND - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

25571.3
GTEx sample id Sample description nTPM
Minor Salivary Gland
Average nTPM: 25571.3
Samples: 181

Max nTPM: 137817.0
Min nTPM: 0.0
Std nTPM: 28149.5
Median nTPM: 16425.9
GTEX-1A3MV-1726-SM-72D68 30-39 years, male 137817.0
GTEX-1POEN-2226-SM-DPRXV 30-39 years, female 132779.1
GTEX-13VXT-1726-SM-5IFF5 20-29 years, female 132559.4
GTEX-12WSM-1826-SM-5BC64 60-69 years, male 113570.4
GTEX-15SHV-2226-SM-6M464 60-69 years, male 111957.0
GTEX-1S5ZU-0926-SM-HPAEX 20-29 years, female 93392.2
GTEX-ZQUD-2126-SM-51MSY 30-39 years, male 90725.2
GTEX-1LSNL-2626-SM-EV7AT 50-59 years, male 90613.5
GTEX-13OVL-2926-SM-5IFG3 50-59 years, male 88849.9
GTEX-1KD5A-2226-SM-EV79U 50-59 years, male 76034.5
GTEX-1LBAC-0626-SM-D3L9T 20-29 years, male 73280.9
GTEX-15RJE-2726-SM-6LPJ1 40-49 years, male 72556.5
GTEX-1AMEY-1126-SM-72D79 30-39 years, female 72218.5
GTEX-YJ8A-1826-SM-GNTAB 20-29 years, male 70951.5
GTEX-1GZ2Q-2526-SM-9KNVW 40-49 years, male 70783.3
GTEX-14B4R-1426-SM-5Q5CG 30-39 years, male 69664.8
GTEX-1C4CL-2026-SM-731EB 30-39 years, male 69406.6
GTEX-1R9K4-0526-SM-E76P1 60-69 years, male 68755.7
GTEX-1S5VW-1026-SM-HK797 60-69 years, male 66477.0
GTEX-14PJN-1726-SM-69LO7 30-39 years, male 65881.2
GTEX-1IOXB-2826-SM-AHZ32 50-59 years, male 62580.4
GTEX-1HFI6-2826-SM-GA91I 40-49 years, male 61843.5
GTEX-12WSN-2226-SM-5DUXT 40-49 years, male 59720.8
GTEX-11TUW-2426-SM-5EQKB 60-69 years, male 56982.0
GTEX-1IDJD-2526-SM-C1YSA 30-39 years, male 54756.0
GTEX-1RAZA-0626-SM-EAZ4H 20-29 years, male 54400.7
GTEX-1KD4Q-2526-SM-CXZKL 40-49 years, male 53928.5
GTEX-13NYB-2426-SM-5IFF4 40-49 years, male 53030.6
GTEX-11NV4-1926-SM-5N9D4 60-69 years, male 50020.5
GTEX-X3Y1-1926-SM-4PQZO 40-49 years, male 48015.2
GTEX-1B8KZ-1726-SM-73KV7 50-59 years, male 47600.9
GTEX-1LVAM-0626-SM-HPAFZ 50-59 years, female 47034.9
GTEX-WYVS-2026-SM-4RGNS 40-49 years, female 44466.6
GTEX-XGQ4-2626-SM-4AT6B 50-59 years, male 44087.8
GTEX-11P82-0926-SM-5986X 20-29 years, male 43871.4
GTEX-11WQK-2926-SM-5EQKT 50-59 years, male 43113.7
GTEX-1RQED-2926-SM-HPAFT 60-69 years, male 42962.8
GTEX-1IKJJ-2826-SM-GA8ZM 60-69 years, male 39917.2
GTEX-14PN4-2526-SM-686ZG 50-59 years, male 39481.3
GTEX-11EQ9-2026-SM-5P9JI 30-39 years, male 38660.9
GTEX-1B97J-2126-SM-79OL6 50-59 years, female 38537.2
GTEX-1RNSC-2926-SM-EV79L 60-69 years, male 38322.7
GTEX-18A7B-2826-SM-7KFTK 70-79 years, male 37629.0
GTEX-1QP9N-2026-SM-DPRZT 30-39 years, male 37609.4
GTEX-11ZTT-2226-SM-5CVLP 60-69 years, female 36791.3
GTEX-1I1HK-2526-SM-A96SM 60-69 years, male 35868.5
GTEX-YB5K-1726-SM-5IFIZ 40-49 years, female 35781.4
GTEX-ZE7O-2926-SM-51MSG 50-59 years, female 35776.5
GTEX-1LKK1-2926-SM-EVR4Z 50-59 years, female 35586.5
GTEX-1IE54-0826-SM-AHZ2Z 40-49 years, female 35236.4
GTEX-11P81-2026-SM-5P9GT 30-39 years, female 34259.9
GTEX-13G51-2426-SM-5LZY8 60-69 years, male 34110.4
GTEX-1GN1W-2526-SM-9JGHX 50-59 years, female 32828.1
GTEX-1C64N-2926-SM-79OLM 50-59 years, male 32691.8
GTEX-1S82P-0726-SM-EVR4O 60-69 years, female 32452.3
GTEX-1H4P4-2026-SM-9WPNV 50-59 years, male 31859.7
GTEX-1HSGN-0626-SM-A9G2E 40-49 years, female 31777.5
GTEX-1LH75-2726-SM-HL11E 50-59 years, female 31539.5
GTEX-1445S-2926-SM-5O993 60-69 years, male 29365.0
GTEX-1LVA9-2526-SM-EVR5H 50-59 years, male 28936.9
GTEX-1MCQQ-2226-SM-DLHC4 60-69 years, male 28818.5
GTEX-111FC-2926-SM-5GZY7 60-69 years, male 28676.9
GTEX-12WSL-2126-SM-5GCNG 50-59 years, male 28575.4
GTEX-13OVK-1826-SM-6PALE 40-49 years, male 28385.4
GTEX-1OJC4-3126-SM-EXOJK 50-59 years, female 27980.0
GTEX-1I6K6-0626-SM-ARU7J 30-39 years, male 27077.3
GTEX-1C6VR-0726-SM-7P8OV 60-69 years, male 26946.4
GTEX-1IY9M-2926-SM-A96TH 60-69 years, male 26694.0
GTEX-17MFQ-1626-SM-7938Z 20-29 years, male 25146.4
GTEX-1GTWX-2526-SM-9JGHG 60-69 years, male 24862.5
GTEX-1NHNU-2226-SM-GRR2I 50-59 years, male 24544.1
GTEX-1IDJC-1626-SM-AHZ2R 50-59 years, male 23244.4
GTEX-1EH9U-2926-SM-7DHLX 60-69 years, male 23241.7
GTEX-1MCC2-2226-SM-EV7AJ 30-39 years, female 23072.3
GTEX-1HSMQ-0926-SM-A96SI 50-59 years, male 21954.1
GTEX-14E1K-2626-SM-664OJ 50-59 years, male 21148.6
GTEX-1GMR2-2026-SM-7MKHK 50-59 years, male 20811.5
GTEX-1GN1V-2926-SM-9JGI3 60-69 years, male 20650.0
GTEX-Y111-2626-SM-4TT24 50-59 years, male 20244.8
GTEX-1LC47-2426-SM-DHXKK 60-69 years, male 20174.9
GTEX-YF7O-2226-SM-5CVN8 50-59 years, male 19953.8
GTEX-WHSB-2326-SM-4M1XK 50-59 years, male 19336.4
GTEX-X261-2426-SM-4PQZU 50-59 years, male 18867.5
GTEX-ZG7Y-2426-SM-DO11H 50-59 years, male 18855.6
GTEX-1HSEH-1826-SM-A96SA 60-69 years, male 18713.4
GTEX-13QJC-2326-SM-5Q5CD 60-69 years, female 18358.4
GTEX-WOFM-2126-SM-4M9R4 20-29 years, male 17430.8
GTEX-13O21-1926-SM-5MR39 50-59 years, male 17134.1
GTEX-1GF9X-0226-SM-7P8SM 40-49 years, female 17090.8
GTEX-1KANC-1326-SM-CYPT8 50-59 years, female 16937.9
GTEX-14PJ3-1526-SM-664O9 50-59 years, male 16425.9
GTEX-1HSMP-1926-SM-GA8Z5 70-79 years, male 16344.3
GTEX-1QEPI-0626-SM-E76QE 60-69 years, female 16257.7
GTEX-1I4MK-1326-SM-B2LWT 50-59 years, female 15845.1
GTEX-1314G-2026-SM-5LZUM 30-39 years, male 15215.9
GTEX-13JVG-2926-SM-5J2N9 60-69 years, male 15068.1
GTEX-1339X-2326-SM-5HL5B 40-49 years, male 14767.9
GTEX-13113-1526-SM-5EGHV 60-69 years, female 14605.8
GTEX-145ME-1626-SM-5RQI3 40-49 years, female 14359.8
GTEX-1B8SF-1826-SM-731DJ 60-69 years, male 14124.9
GTEX-1H1CY-2326-SM-9OSXW 60-69 years, female 13355.4
GTEX-Z9EW-1426-SM-HPAG9 40-49 years, male 13201.3
GTEX-17KNJ-2726-SM-7KFRE 50-59 years, male 12969.9
GTEX-1JN6P-2526-SM-CNNPX 60-69 years, male 11948.2
GTEX-X15G-2126-SM-4PQZR 50-59 years, female 11810.8
GTEX-1ICLY-0626-SM-GA915 50-59 years, male 11173.0
GTEX-W5X1-2426-SM-HPAGA 40-49 years, female 10940.2
GTEX-178AV-1426-SM-6LLID 40-49 years, male 10641.5
GTEX-18D9U-2226-SM-7KFTN 40-49 years, male 10276.7
GTEX-1J8QM-1826-SM-A96TA 60-69 years, female 9705.9
GTEX-X5EB-1726-SM-4E3J7 40-49 years, male 9659.2
GTEX-WH7G-2126-SM-4M1XU 40-49 years, male 9540.9
GTEX-1JN1M-2426-SM-ARU93 60-69 years, female 9317.9
GTEX-1IDJV-2326-SM-GA8ZL 60-69 years, male 8731.9
GTEX-1NSGN-0626-SM-E9J35 50-59 years, male 8426.7
GTEX-1QP28-2026-SM-F2I3M 50-59 years, female 8323.2
GTEX-Y5V6-2226-SM-4VDTC 60-69 years, male 8188.1
GTEX-1I6K7-0926-SM-A96SV 40-49 years, male 8187.6
GTEX-13CF2-2426-SM-5LZYL 60-69 years, male 7849.2
GTEX-13OVI-2326-SM-5KM47 60-69 years, female 7180.3
GTEX-1J8EW-2826-SM-A96T9 60-69 years, female 6943.0
GTEX-1R9PM-1726-SM-E76T2 20-29 years, male 6598.4
GTEX-1LVAO-2626-SM-EVR4S 60-69 years, male 6577.1
GTEX-XMK1-2626-SM-4B65R 40-49 years, male 6051.4
GTEX-15CHC-1226-SM-686ZH 60-69 years, female 5930.6
GTEX-ZP4G-1926-SM-57WDZ 20-29 years, female 5778.1
GTEX-131XF-2826-SM-5EGKH 60-69 years, male 5718.6
GTEX-1117F-3026-SM-5GZYU 60-69 years, female 5626.1
GTEX-1P4AB-2926-SM-EXOJR 50-59 years, male 5337.0
GTEX-1AYD5-2726-SM-7MXVG 50-59 years, male 5299.4
GTEX-15SDE-1226-SM-HAV36 50-59 years, female 5227.0
GTEX-14JIY-3026-SM-6EU1R 60-69 years, male 5171.6
GTEX-1HR9M-2526-SM-A9G3J 60-69 years, male 5043.4
GTEX-146FR-1226-SM-5MR78 60-69 years, female 4982.4
GTEX-1HFI7-2426-SM-B2LXV 50-59 years, female 4889.4
GTEX-1B932-0626-SM-731EM 40-49 years, female 4807.8
GTEX-1QMI2-0426-SM-EWRND 60-69 years, male 4717.2
GTEX-1AX8Z-0626-SM-731EH 60-69 years, male 4637.7
GTEX-1OJC3-1026-SM-E6CQK 20-29 years, male 4316.5
GTEX-1PDJ9-2126-SM-HPAFH 20-29 years, male 3820.9
GTEX-18QFQ-0626-SM-718AW 30-39 years, male 3743.2
GTEX-WFJO-2026-SM-4LVM3 30-39 years, male 3692.9
GTEX-18A67-0626-SM-7KFSL 50-59 years, male 3460.4
GTEX-ZA64-1726-SM-5CVMF 20-29 years, male 3347.1
GTEX-ZXG5-2826-SM-5NQ8T 60-69 years, male 2864.5
GTEX-13111-2326-SM-5LZUQ 50-59 years, male 2813.8
GTEX-ZPU1-2326-SM-57WEP 40-49 years, male 2710.0
GTEX-1JKYR-0726-SM-AHZ3K 20-29 years, male 2132.3
GTEX-1QCLZ-2526-SM-EXUST 60-69 years, female 1815.0
GTEX-1PIEJ-0626-SM-DTX99 20-29 years, female 1802.8
GTEX-1MGNQ-1926-SM-DTX8L 40-49 years, male 1724.1
GTEX-Y3I4-1926-SM-4TT8L 50-59 years, male 1641.8
GTEX-1PPH8-1526-SM-E6CQO 20-29 years, male 1582.2
GTEX-WY7C-1426-SM-4OND1 50-59 years, male 1564.2
GTEX-Y5LM-1826-SM-4VDT9 40-49 years, female 1537.8
GTEX-1GPI7-0326-SM-7MKH6 20-29 years, male 1458.8
GTEX-1AX9K-2126-SM-72D7K 50-59 years, male 1424.8
GTEX-1C64O-0626-SM-7DHL1 60-69 years, male 1385.1
GTEX-1R9PO-2626-SM-E6CPU 60-69 years, female 1348.6
GTEX-1CB4I-2526-SM-7MKG1 50-59 years, male 1314.4
GTEX-1HGF4-2326-SM-GA91Q 60-69 years, male 1065.7
GTEX-ZC5H-2726-SM-5KLZW 40-49 years, female 975.0
GTEX-15EU6-2626-SM-7KUN4 50-59 years, male 971.3
GTEX-1R9K5-0626-SM-DPRZB 50-59 years, male 929.0
GTEX-ZT9W-2126-SM-51MSF 50-59 years, male 772.5
GTEX-1J1R8-1826-SM-AHZ3B 40-49 years, male 702.6
GTEX-1S83E-0626-SM-E9TKC 40-49 years, male 387.4
GTEX-XV7Q-2426-SM-4BRV8 40-49 years, female 283.3
GTEX-13NYC-2626-SM-5K7VN 60-69 years, male 158.5
GTEX-11ZTS-3026-SM-5EQM7 60-69 years, female 140.5
GTEX-1HCU7-0126-SM-C1YR3 50-59 years, male 59.2
GTEX-ZAB5-2326-SM-5IJFR 50-59 years, male 24.0
GTEX-11EMC-2526-SM-5PNVU 60-69 years, female 10.6
GTEX-12BJ1-2226-SM-5BC6G 60-69 years, male 4.3
GTEX-1O97I-2826-SM-HPAEO 60-69 years, male 3.7
GTEX-131XH-2626-SM-5GCNP 50-59 years, male 2.7
GTEX-ZF29-2126-SM-DNZYX 60-69 years, female 0.9
GTEX-ZLWG-2026-SM-DO11F 50-59 years, female 0.7
GTEX-1192X-2926-SM-5N9BA 50-59 years, male 0.2
GTEX-13QBU-2126-SM-5KLZN 40-49 years, female 0.0
GTEX-ZLFU-2226-SM-EXUS7 40-49 years, male 0.0
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SALIVARY GLAND - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

102344.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Parotid gland
Scaled Tags Per Million: 593.8
FF:10199-103F1 23 years, male 593.8
Salivary gland
Scaled Tags Per Million: 102344.6
FF:10093-102C3 16-60 years, mixed 102344.6
Submaxillary gland
Scaled Tags Per Million: 78815.2
FF:10202-103F4 24 years, male 78815.2

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