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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:0.7 nTPM
HPA Brain:14.6 nTPM
GTEx:0.7 nTPM
FANTOM5:0.0 Scaled Tags Per Million
Pig:2.4 nTPM
Mouse:0.0 nTPM
Allen mouse:0.1 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

14.6
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 8.6
2586 Male, age 75, left hemisphere 11.5
2411 Female, age 72, unknown 9.5
1870 Female, age 42, unknown 9.1
2828 Female, age 72, unknown 8.8
1830 Male, age 51, unknown 8.3
2219 Male, age 76, both hemispheres 8.3
2666 Male, age 74, left hemisphere 8.3
1827 Male, age 72, unknown 8.1
1833 Male, age 53, unknown 7.6
2019 Male, age 18, unknown 6.9
Dorsal raphe nucleus
nTPM: 10.2
2750 Male, age 76, both hemispheres 12.7
2298 Female, age 72, unknown 12.3
2047 Male, age 72, unknown 10.1
2016 Female, age 72, unknown 8.3
1828 Male, age 53, unknown 7.7
Inferior colliculus
nTPM: 8.7
2097 Female, age 72, unknown 10.5
1848 Female, age 42, unknown 8.4
2849 Male, age 72, unknown 8.2
1890 Male, age 53, unknown 7.7
Median raphe nucleus
nTPM: 14.6
2220 Male, age 76, midline 14.6
Periaquaductal grey, anterior
nTPM: 11.1
1795 Male, age 51, unknown 12.2
1947 Male, age 18, unknown 10.7
2502 Female, age 75, unknown 10.4
Periaquaductal grey, dorsal
nTPM: 8.2
1840 Male, age 53, unknown 9.7
2850 Male, age 76, both hemispheres 8.0
2464 Female, age 72, unknown 7.6
1831 Male, age 72, unknown 7.5
Periaquaductal grey, lateral
nTPM: 8.6
2140 Male, age 76, both hemispheres 9.2
2272 Male, age 74, both hemispheres 8.6
2053 Male, age 18, unknown 7.8
Pretectal area
nTPM: 7.3
2224 Female, age 72, unknown 11.3
2825 Male, age 18, unknown 9.4
2273 Male, age 74, both hemispheres 8.3
2007 Male, age 72, unknown 7.5
2407 Male, age 75, both hemispheres 7.4
2667 Female, age 75, unknown 6.9
2316 Male, age 76, right hemisphere 6.5
1816 Male, age 51, unknown 6.4
1817 Female, age 42, unknown 5.9
1815 Male, age 53, unknown 5.7
1944 Female, age 72, unknown 4.8
Red nucleus
nTPM: 7.3
2584 Male, age 75, left hemisphere 10.5
2227 Male, age 72, unknown 8.5
2503 Female, age 72, unknown 8.3
2725 Female, age 75, unknown 8.1
2769 Male, age 72, unknown 8.1
2588 Male, age 74, left hemisphere 7.4
2785 Male, age 18, unknown 6.9
1954 Female, age 42, unknown 6.7
1904 Male, age 53, unknown 6.5
1821 Female, age 72, unknown 5.7
1865 Male, age 51, unknown 5.7
2823 Male, age 76, right hemisphere 4.9
Substantia nigra
nTPM: 7.2
1941 Male, age 53, unknown 8.8
2583 Male, age 75, right hemisphere 8.5
1916 Female, age 42, unknown 8.2
2665 Male, age 74, both hemispheres 8.0
2241 Male, age 72, unknown 7.4
2699 Male, age 18, unknown 7.3
2590 Female, age 75, unknown 7.1
1889 Female, age 72, unknown 6.9
1851 Male, age 51, unknown 6.7
2409 Female, age 72, unknown 3.6
Superior colliculus
nTPM: 7.6
2664 Male, age 75, both hemispheres 10.5
1796 Male, age 53, unknown 10.3
1839 Male, age 51, unknown 9.3
2261 Male, age 18, unknown 8.0
2587 Male, age 74, left hemisphere 7.5
2668 Female, age 75, unknown 7.3
1995 Male, age 72, unknown 6.0
2087 Female, age 72, unknown 6.0
1913 Female, age 42, unknown 5.9
1895 Male, age 76, right hemisphere 5.7
Ventral tegmental area
nTPM: 8.2
2021 Male, age 53, unknown 9.1
1942 Male, age 51, unknown 8.9
2218 Male, age 76, both hemispheres 8.7
1915 Female, age 42, unknown 8.2
2223 Female, age 72, unknown 7.1
2410 Female, age 72, unknown 7.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 0.7
Samples: 139

Max nTPM: 2.6
Min nTPM: 0.0
Std nTPM: 0.5
Median nTPM: 0.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 2.6
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 2.5
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 2.4
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1.9
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1.8
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 1.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1.7
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1.6
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 1.6
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 1.5
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1.5
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1.5
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1.4
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 1.4
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1.4
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1.4
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 1.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1.3
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 1.2
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 1.2
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 1.2
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 1.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 1.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 1.1
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 1.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1.1
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1.0
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1.0
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 0.9
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 0.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 0.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 0.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 0.9
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 0.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 0.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 0.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 0.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 0.8
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 0.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 0.8
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 0.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 0.8
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 0.8
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 0.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 0.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 0.8
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 0.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 0.7
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 0.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 0.7
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 0.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 0.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 0.7
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 0.7
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 0.6
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 0.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 0.6
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 0.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 0.6
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 0.6
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 0.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 0.6
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 0.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 0.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 0.6
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 0.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 0.5
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 0.5
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 0.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 0.5
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 0.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 0.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 0.5
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 0.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 0.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 0.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 0.4
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 0.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 0.4
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 0.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 0.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 0.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 0.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 0.4
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 0.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 0.4
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 0.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 0.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 0.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 0.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 0.4
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 0.4
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 0.3
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 0.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 0.3
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 0.3
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 0.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 0.3
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 0.3
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 0.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 0.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 0.3
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 0.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 0.3
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 0.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 0.2
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 0.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 0.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 0.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 0.2
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 0.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 0.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 0.2
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 0.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 0.2
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 0.1
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 0.1
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 0.1
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 0.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 0.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 0.0
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 0.0
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 0.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 0.0
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 0.0
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 0.0
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 0.0
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 0.0
FF:10158-103A5 76 years, female 0.0

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 2.1
Samples: 4

Max nTPM: 2.6
Min nTPM: 1.6
Sample A Female 1.6
Sample B Female 2.3
Sample C Male 2.0
Sample D Male 2.6
Midbrain
nTPM: 1.9
Samples: 4

Max nTPM: 2.5
Min nTPM: 1.2
Sample A Female 1.2
Sample B Female 2.4
Sample C Male 1.6
Sample D Male 2.5
Periaqueductal gray
nTPM: 2.4
Samples: 3

Max nTPM: 3.0
Min nTPM: 1.5
Sample B Female 3.0
Sample C Male 2.7
Sample D Male 1.5
Superior colliculi
nTPM: 2.0
Samples: 4

Max nTPM: 2.8
Min nTPM: 1.5
Sample A Female 1.6
Sample B Female 2.8
Sample C Male 1.5
Sample D Male 2.1

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A Male 0.0
Sample B Male 0.0
Sample C Female 0.0
Sample D Female 0.0

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

0.1
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 0.1
71724467 Antisense, RP_050927_03_F04, Mouse strain C57BL/6J (56 days, male) 0.1

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