CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Not detected
Glial cells: Low
Neuronal cells: Medium
Neuropil: High
RNA expressioni
Consensus:190.7 nTPM
HPA:73.1 nTPM
HPA Brain:192.6 nTPM
HPA PFC Brain:79.5 nTPM
GTEx:190.7 nTPM
FANTOM5:166.6 Scaled Tags Per Million
Pig:157.6 nTPM
Mouse:38.3 nTPM
Allen mouse:13.4 Expression energy
BRAIN - SINGLE CELL RNA EXPRESSION

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA044133
Endothelial cells Not detected
Glial cells Low
Neuronal cells Medium
Neuropil High



CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 73.1
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 87.3
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 41.6
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 90.4
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 192.6
Sample id Sample description nTPM
Angular gyrus
nTPM: 115.6
2722 Male, age 61, left hemisphere 202.4
2260 Female, age 72, left hemisphere 120.8
2602 Female, age 94, right hemisphere 119.3
1866 Male, age 76, both hemispheres 112.5
1790 Male, age 76, right hemisphere 107.6
2221 Female, age 67, right hemisphere 103.6
2265 Female, age 91, left hemisphere 85.0
2103 Male, age 75, left hemisphere 73.4
Anterior cingulate cortex, supragenual-dorsal
nTPM: 120.5
2478 Female, age 67, right hemisphere 136.5
2342 Female, age 94, right hemisphere 130.7
2547 Male, age 74, left hemisphere 124.1
2472 Male, age 75, left hemisphere 106.7
1896 Female, age 85, right hemisphere 104.7
Anterior cingulate cortex, supragenual-ventral
nTPM: 124.5
1755 Female, age 94, right hemisphere 150.2
2538 Male, age 75, left hemisphere 146.1
1761 Male, age 74, left hemisphere 116.0
2479 Female, age 67, right hemisphere 106.0
1950 Female, age 85, right hemisphere 104.1
Anterior insular cortex, dorsal
nTPM: 104.8
2670 Male, age 75, left hemisphere 123.8
2001 Male, age 76, right hemisphere 104.8
2235 Female, age 91, right hemisphere 98.5
2506 Female, age 94, right hemisphere 92.3
Anterior insular cortex, ventral
nTPM: 109.3
1925 Female, age 91, left hemisphere 131.9
2596 Male, age 75, left hemisphere 114.2
1852 Male, age 76, left hemisphere 113.0
2262 Female, age 67, right hemisphere 110.4
2757 Male, age 61, right hemisphere 97.5
2507 Female, age 94, left hemisphere 88.7
Area parastriata, inferior
nTPM: 109.6
1760 Female, age 67, left hemisphere 169.0
1758 Female, age 72, right hemisphere 127.4
2421 Female, age 91, left hemisphere 107.8
1789 Male, age 76, right hemisphere 107.2
2268 Male, age 61, right hemisphere 104.5
2509 Female, age 94, left hemisphere 78.8
2234 Male, age 75, left hemisphere 72.3
Area parastriata, parietal
nTPM: 96.5
2680 Female, age 94, right hemisphere 130.3
2236 Female, age 91, left hemisphere 109.8
2233 Male, age 61, right hemisphere 93.1
1785 Male, age 76, right hemisphere 91.7
2420 Male, age 75, left hemisphere 57.3
Area parastriata, superior
nTPM: 134.3
2435 Male, age 61, left hemisphere 165.2
2881 Male, age 76, left hemisphere 163.0
1773 Female, age 91, left hemisphere 155.4
2684 Female, age 67, left hemisphere 150.0
2604 Female, age 94, right hemisphere 97.2
2419 Male, age 75, right hemisphere 75.0
Area parastriata, temporal
nTPM: 114.7
2471 Male, age 75, left hemisphere 142.9
1804 Male, age 76, right hemisphere 121.3
2681 Female, age 94, right hemisphere 108.1
2267 Male, age 61, right hemisphere 103.9
2424 Female, age 67, left hemisphere 97.4
Area striata
nTPM: 95.8
1753 Female, age 72, right hemisphere 131.9
2679 Female, age 94, right hemisphere 116.6
2427 Female, age 91, left hemisphere 104.9
2417 Male, age 61, right hemisphere 92.5
1884 Male, age 76, left hemisphere 72.6
2002 Female, age 91, right hemisphere 55.9
Claustrum
nTPM: 109.3
2196 Female, age 79, unknown 139.0
2568 Male, age 61, both hemispheres 127.5
2198 Male, age 80, both hemispheres 123.8
2284 Female, age 91, both hemispheres 114.9
2645 Female, age 72, unknown 114.5
1956 Male, age 74, unknown 110.2
2491 Male, age 75, both hemispheres 103.1
2292 Female, age 85, both hemispheres 87.0
2392 Female, age 94, both hemispheres 64.2
Frontal eye field
nTPM: 120.6
2761 Female, age 94, left hemisphere 132.5
2543 Male, age 74, left hemisphere 131.7
2441 Male, age 75, left hemisphere 128.0
2147 Male, age 61, left hemisphere 90.5
Frontal operculum
nTPM: 93.7
2781 Female, age 85, right hemisphere 121.2
2348 Male, age 75, left hemisphere 91.0
2030 Male, age 61, right hemisphere 68.9
Fusiform gyrus
nTPM: 123.5
2784 Female, age 85, left hemisphere 167.2
2617 Female, age 94, left hemisphere 138.4
1807 Male, age 76, left hemisphere 132.7
2112 Male, age 80, both hemispheres 120.0
2074 Female, age 91, left hemisphere 106.7
2433 Female, age 72, left hemisphere 103.2
2431 Male, age 75, right hemisphere 96.3
Inferior frontal gyrus, opercular
nTPM: 136.8
2867 Male, age 75, left hemisphere 187.0
2873 Female, age 85, left hemisphere 179.2
2868 Male, age 75, right hemisphere 149.5
2875 Female, age 67, left hemisphere 143.9
2865 Male, age 61, left hemisphere 136.7
2869 Male, age 74, left hemisphere 124.6
2872 Female, age 94, right hemisphere 123.8
2866 Male, age 61, right hemisphere 119.2
2871 Female, age 94, left hemisphere 106.3
2874 Female, age 85, right hemisphere 98.1
Inferior parietal lobule
nTPM: 122.9
2606 Female, age 67, right hemisphere 146.9
2876 Male, age 76, right hemisphere 129.4
2599 Female, age 94, left hemisphere 112.0
2418 Male, age 75, left hemisphere 103.2
Inferior temporal gyrus
nTPM: 130.7
1880 Male, age 80, right hemisphere 146.1
2430 Male, age 75, right hemisphere 142.4
1970 Female, age 85, right hemisphere 127.8
1965 Female, age 91, left hemisphere 124.6
1808 Male, age 76, left hemisphere 122.1
2689 Female, age 94, right hemisphere 121.3
Intraparietal deep sulcus
nTPM: 118.0
2669 Male, age 75, left hemisphere 157.0
2600 Female, age 94, right hemisphere 126.8
2607 Female, age 67, right hemisphere 126.3
2798 Male, age 76, left hemisphere 118.0
2230 Male, age 61, right hemisphere 104.7
2102 Female, age 91, left hemisphere 75.3
Lingual gyrus
nTPM: 142.4
2688 Male, age 75, right hemisphere 182.3
2838 Male, age 80, right hemisphere 153.9
2618 Female, age 94, left hemisphere 147.5
1893 Male, age 76, left hemisphere 122.2
2073 Female, age 85, left hemisphere 106.3
Middle cingulate cortex
nTPM: 123.9
2640 Female, age 94, right hemisphere 152.3
2633 Male, age 74, left hemisphere 124.0
2539 Male, age 75, left hemisphere 122.2
2357 Female, age 67, right hemisphere 113.5
2028 Female, age 85, left hemisphere 107.7
Middle temporal gyrus
nTPM: 136.4
2611 Male, age 75, right hemisphere 182.1
1819 Male, age 80, right hemisphere 138.3
2616 Female, age 94, left hemisphere 128.1
1799 Male, age 76, left hemisphere 119.5
2034 Female, age 91, right hemisphere 113.8
Occipital cortex
nTPM: 134.2
2608 Female, age 67, both hemispheres 169.5
2677 Female, age 67, right hemisphere 132.3
2470 Male, age 75, right hemisphere 127.4
1842 Male, age 76, right hemisphere 122.1
2426 Male, age 75, midline 119.7
Olfactory area
nTPM: 119.4
1805 Female, age 85, right hemisphere 143.5
2756 Female, age 67, right hemisphere 134.1
2222 Female, age 67, right hemisphere 132.6
2542 Male, age 74, left hemisphere 107.7
2440 Male, age 75, left hemisphere 104.3
2352 Female, age 94, right hemisphere 94.1
Olfactory tubercle
nTPM: 131.2
2856 Male, age 75, right hemisphere 142.6
1998 Female, age 91, both hemispheres 137.7
1846 Male, age 80, right hemisphere 134.3
2487 Female, age 94, left hemisphere 110.3
Orbitofrontal gyrus, anterior
nTPM: 192.6
2863 Female, age 85, right hemisphere 330.2
2864 Female, age 67, left hemisphere 129.6
2862 Female, age 85, left hemisphere 118.0
Paracentral lobule, anterior
nTPM: 122.9
1776 Female, age 85, right hemisphere 144.1
2474 Male, age 74, left hemisphere 137.3
1754 Male, age 75, left hemisphere 137.1
2638 Female, age 94, right hemisphere 118.2
2340 Female, age 67, right hemisphere 110.8
1926 Male, age 61, left hemisphere 90.1
Paracentral lobule, posterior
nTPM: 111.6
1775 Female, age 85, right hemisphere 136.5
1764 Male, age 74, right hemisphere 116.4
2446 Male, age 75, left hemisphere 112.7
2345 Male, age 61, left hemisphere 105.0
2551 Female, age 94, right hemisphere 87.4
Parietal operculum
nTPM: 155.2
2719 Male, age 75, left hemisphere 230.7
1763 Male, age 74, left hemisphere 156.5
2552 Female, age 94, right hemisphere 121.6
2356 Female, age 67, right hemisphere 111.7
Parieto-insular cortex
nTPM: 122.6
2671 Male, age 75, left hemisphere 142.6
1976 Female, age 91, right hemisphere 126.3
2831 Male, age 76, right hemisphere 124.0
2508 Female, age 94, right hemisphere 115.7
2232 Male, age 61, right hemisphere 104.5
Parieto-occipital transitional area
nTPM: 123.4
2683 Female, age 67, left hemisphere 145.3
2674 Female, age 94, right hemisphere 139.6
2468 Male, age 75, left hemisphere 126.8
1784 Male, age 76, right hemisphere 103.1
2270 Male, age 61, right hemisphere 102.2
Piriform cortex
nTPM: 68.1
2347 Male, age 75, right hemisphere 70.9
2153 Female, age 85, left hemisphere 65.3
Postcentral gyrus
nTPM: 157.9
2533 Male, age 75, right hemisphere 157.9
Postcentral gyrus, dorsal
nTPM: 110.7
2544 Male, age 74, left hemisphere 177.6
2350 Male, age 75, left hemisphere 118.7
1836 Female, age 85, right hemisphere 110.7
2151 Male, age 61, left hemisphere 90.4
2477 Female, age 94, right hemisphere 88.1
2339 Female, age 67, right hemisphere 78.8
Postcentral gyrus, middle
nTPM: 126.6
2545 Male, age 74, left hemisphere 221.2
2444 Male, age 75, left hemisphere 128.7
1897 Female, age 85, right hemisphere 106.6
2146 Female, age 67, right hemisphere 101.3
2248 Male, age 61, left hemisphere 75.0
Postcentral gyrus, ventral
nTPM: 110.4
2445 Male, age 75, left hemisphere 126.9
2836 Female, age 94, right hemisphere 123.5
2024 Female, age 85, right hemisphere 80.8
Posterior cingulate cortex
nTPM: 131.3
2473 Male, age 75, left hemisphere 144.3
1759 Male, age 74, right hemisphere 134.7
2553 Female, age 94, right hemisphere 114.9
Posterior cingulate cortex, dorsal
nTPM: 109.2
2540 Male, age 75, right hemisphere 128.1
2556 Female, age 67, right hemisphere 118.2
2076 Female, age 85, right hemisphere 117.2
2641 Female, age 94, right hemisphere 106.0
2343 Male, age 61, left hemisphere 103.0
2634 Male, age 74, left hemisphere 82.8
Posterior cingulate cortex, ventral
nTPM: 107.9
1762 Female, age 94, right hemisphere 139.2
2541 Male, age 75, right hemisphere 111.3
2635 Male, age 74, left hemisphere 107.3
2346 Male, age 61, left hemisphere 106.5
1994 Female, age 85, right hemisphere 101.2
2448 Female, age 67, right hemisphere 81.8
Posterior insular cortex
nTPM: 134.8
2832 Female, age 91, right hemisphere 169.2
2597 Male, age 75, left hemisphere 149.4
2511 Female, age 67, right hemisphere 147.4
1823 Male, age 76, right hemisphere 115.3
2603 Female, age 94, left hemisphere 115.2
2231 Male, age 61, left hemisphere 112.1
Precentral gyrus
nTPM: 151.7
2557 Male, age 75, right hemisphere 151.7
Precentral gyrus, dorsal
nTPM: 97.9
1756 Male, age 74, left hemisphere 127.4
2354 Female, age 67, right hemisphere 107.6
2442 Male, age 75, left hemisphere 88.0
2476 Female, age 94, right hemisphere 68.6
Precentral gyrus, middle
nTPM: 96.1
2549 Female, age 94, right hemisphere 125.5
1969 Female, age 67, right hemisphere 104.2
1909 Male, age 61, left hemisphere 85.2
2475 Male, age 74, right hemisphere 83.3
2443 Male, age 75, left hemisphere 82.2
Precentral gyrus, ventral
nTPM: 130.7
2630 Male, age 75, left hemisphere 165.2
2678 Male, age 74, left hemisphere 164.3
2550 Female, age 94, right hemisphere 116.3
2662 Female, age 67, right hemisphere 77.1
Precuneus
nTPM: 123.7
2594 Male, age 61, left hemisphere 164.2
1780 Female, age 91, right hemisphere 139.1
2673 Female, age 94, right hemisphere 125.1
1782 Male, age 76, right hemisphere 119.5
2510 Female, age 67, right hemisphere 115.8
2467 Male, age 75, right hemisphere 78.3
Premotor cortex, dorsal
nTPM: 103.5
2536 Male, age 75, left hemisphere 125.9
1878 Female, age 85, right hemisphere 112.5
2631 Male, age 74, left hemisphere 107.0
2554 Female, age 67, right hemisphere 90.9
2027 Male, age 61, left hemisphere 81.4
Premotor cortex, ventral
nTPM: 125.6
1757 Male, age 74, left hemisphere 152.2
1779 Male, age 61, left hemisphere 136.1
1777 Female, age 67, left hemisphere 131.0
2637 Female, age 94, right hemisphere 130.2
1881 Female, age 85, right hemisphere 105.1
2349 Male, age 75, left hemisphere 98.8
Retrosplenial cortex
nTPM: 149.3
2675 Female, age 94, left hemisphere 197.7
1951 Male, age 61, right hemisphere 144.0
1914 Male, age 76, right hemisphere 106.3
Subcentral gyrus, S2
nTPM: 127.9
2839 Female, age 94, right hemisphere 162.3
2555 Female, age 67, right hemisphere 160.3
2762 Male, age 74, left hemisphere 127.9
2351 Male, age 75, left hemisphere 112.2
1964 Female, age 85, right hemisphere 111.0
2072 Male, age 61, left hemisphere 93.9
Superior parietal lobule
nTPM: 111.9
2605 Female, age 67, right hemisphere 149.1
2672 Female, age 94, right hemisphere 144.3
2229 Male, age 61, right hemisphere 110.1
1800 Male, age 76, right hemisphere 83.0
1992 Female, age 91, right hemisphere 72.7
Superior temporal gyrus
nTPM: 131.5
2687 Male, age 75, right hemisphere 176.6
1844 Female, age 91, left hemisphere 137.7
1843 Male, age 76, left hemisphere 128.0
2025 Male, age 80, right hemisphere 109.5
2615 Female, age 94, left hemisphere 105.7
Supplementary motor cortex
nTPM: 120.3
2537 Male, age 75, left hemisphere 168.7
2548 Female, age 94, right hemisphere 134.1
2632 Male, age 74, left hemisphere 101.5
1993 Male, age 61, left hemisphere 76.8
Supramarginal gyrus
nTPM: 120.6
2513 Female, age 72, left hemisphere 135.7
1991 Female, age 91, right hemisphere 127.0
1798 Male, age 76, right hemisphere 122.7
2415 Male, age 61, left hemisphere 116.1
2601 Female, age 94, left hemisphere 101.6
Temporal pole
nTPM: 141.6
1832 Female, age 91, left hemisphere 181.5
1853 Female, age 85, right hemisphere 153.0
2518 Male, age 75, right hemisphere 130.3
2612 Female, age 94, left hemisphere 128.7
1826 Male, age 76, right hemisphere 114.6
Temporo-insular cortex, parainsular gyrus
nTPM: 123.5
2598 Male, age 75, left hemisphere 182.5
2676 Female, age 94, right hemisphere 159.4
1802 Male, age 76, left hemisphere 129.1
2416 Male, age 61, right hemisphere 114.3
2512 Female, age 67, right hemisphere 78.4
2264 Female, age 91, right hemisphere 77.1
Temporo-occipital transitional zone
nTPM: 127.4
1793 Male, age 80, right hemisphere 151.2
1900 Male, age 76, left hemisphere 124.8
2251 Female, age 85, right hemisphere 106.2
Transversal temporal gyrus, anterior
nTPM: 124.3
2610 Male, age 75, right hemisphere 171.4
1888 Female, age 91, left hemisphere 146.8
1910 Male, age 80, right hemisphere 118.1
1809 Male, age 76, right hemisphere 107.6
2522 Female, age 94, left hemisphere 77.4
Transversal temporal gyrus, posterior
nTPM: 109.1
2833 Male, age 80, right hemisphere 134.1
2614 Female, age 94, left hemisphere 114.3
1967 Female, age 91, right hemisphere 113.3
1922 Male, age 76, left hemisphere 98.4
2520 Male, age 75, right hemisphere 85.6

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 79.5
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 64.5
1516 Female, age 85, left hemisphere 121.5
1515 Female, age 94, right hemisphere 106.9
1511 Male, age 61, right hemisphere 68.4
1510 Male, age 61, left hemisphere 68.2
1513 Male, age 74, left hemisphere 48.3
1514 Male, age 74, right hemisphere 46.2
1518 Female, age 67, right hemisphere 41.7
1512 Male, age 75, left hemisphere 40.2
1517 Female, age 67, left hemisphere 38.7
Anterior cingulate gyrus, pregenual-ventral
nTPM: 58.2
1519 Male, age 61, left hemisphere 76.5
1523 Female, age 67, left hemisphere 62.7
1521 Male, age 74, left hemisphere 62.3
1522 Male, age 74, right hemisphere 47.2
1520 Male, age 75, right hemisphere 42.2
Anterior cingulate gyrus, subgenual
nTPM: 65.2
1529 Female, age 85, left hemisphere 142.4
1524 Male, age 61, left hemisphere 68.4
1527 Male, age 74, left hemisphere 67.0
1528 Male, age 74, right hemisphere 58.1
1526 Male, age 75, right hemisphere 41.7
1525 Male, age 75, left hemisphere 40.4
1530 Female, age 67, right hemisphere 38.6
Dorsolateral prefrontal cortex
nTPM: 64.7
1447 Female, age 94, left hemisphere 102.3
1448 Female, age 94, right hemisphere 92.4
1449 Female, age 85, right hemisphere 70.7
1446 Male, age 74, right hemisphere 50.2
1450 Female, age 67, right hemisphere 46.7
1444 Male, age 75, left hemisphere 46.6
1445 Male, age 75, right hemisphere 44.0
Dorsomedial prefrontal cortex
nTPM: 46.5
1440 Male, age 61, right hemisphere 62.2
1439 Male, age 61, left hemisphere 51.7
1442 Male, age 75, right hemisphere 46.8
1441 Male, age 75, left hemisphere 38.8
1443 Female, age 67, right hemisphere 33.2
Frontal cortex
nTPM: 54.6
1578 Female, age 94, left hemisphere 90.8
1580 Female, age 85, left hemisphere 85.6
1579 Female, age 94, right hemisphere 85.0
1581 Female, age 85, right hemisphere 76.9
1573 Male, age 61, right hemisphere 67.5
1577 Male, age 74, right hemisphere 46.5
1572 Male, age 61, left hemisphere 44.3
1576 Male, age 74, left hemisphere 37.5
1574 Male, age 75, left hemisphere 34.7
1583 Female, age 67, right hemisphere 33.4
1575 Male, age 75, right hemisphere 32.0
1582 Female, age 67, left hemisphere 21.4
Frontomarginal cortex
nTPM: 60.0
1470 Female, age 94, right hemisphere 81.5
1469 Female, age 94, left hemisphere 73.3
1465 Male, age 61, left hemisphere 72.6
1471 Female, age 85, left hemisphere 69.4
1466 Male, age 61, right hemisphere 66.9
1467 Male, age 75, right hemisphere 54.3
1468 Male, age 74, left hemisphere 50.7
1473 Female, age 67, right hemisphere 36.9
1472 Female, age 67, left hemisphere 34.6
Frontopolar cortex
nTPM: 51.9
1462 Female, age 94, left hemisphere 81.0
1459 Male, age 61, right hemisphere 74.4
1458 Male, age 61, left hemisphere 63.2
1460 Male, age 75, left hemisphere 49.9
1461 Male, age 75, right hemisphere 44.7
1463 Female, age 67, left hemisphere 28.4
1464 Female, age 67, right hemisphere 21.7
Gyrus rectus
nTPM: 62.9
1479 Female, age 94, right hemisphere 91.7
1478 Female, age 94, left hemisphere 90.7
1480 Female, age 85, left hemisphere 90.1
1474 Male, age 61, left hemisphere 76.6
1475 Male, age 61, right hemisphere 63.4
1476 Male, age 75, left hemisphere 37.2
1477 Male, age 75, right hemisphere 29.1
1481 Female, age 67, left hemisphere 24.4
Inferior frontal gyrus, orbital
nTPM: 58.9
1508 Female, age 85, right hemisphere 119.9
1506 Female, age 94, left hemisphere 116.8
1504 Male, age 74, left hemisphere 68.8
1500 Male, age 61, left hemisphere 62.5
1501 Male, age 61, right hemisphere 49.9
1502 Male, age 75, left hemisphere 48.7
1503 Male, age 75, right hemisphere 44.2
1507 Female, age 85, left hemisphere 30.3
1509 Female, age 67, right hemisphere 26.2
1505 Male, age 74, right hemisphere 21.9
Inferior frontal gyrus, triangular
nTPM: 73.4
1546 Female, age 94, right hemisphere 127.5
1548 Female, age 85, right hemisphere 97.6
1543 Male, age 61, right hemisphere 84.8
1545 Male, age 74, right hemisphere 66.4
1542 Male, age 61, left hemisphere 66.2
1547 Female, age 85, left hemisphere 56.2
1549 Female, age 67, left hemisphere 54.2
1544 Male, age 75, right hemisphere 34.8
Orbitofrontal gyrus, lateral
nTPM: 75.9
1498 Female, age 85, right hemisphere 111.8
1496 Female, age 94, right hemisphere 102.0
1495 Female, age 94, left hemisphere 101.4
1497 Female, age 85, left hemisphere 72.1
1493 Male, age 61, right hemisphere 59.8
1494 Male, age 75, left hemisphere 50.7
1499 Female, age 67, right hemisphere 33.7
Orbitofrontal gyrus, medial
nTPM: 52.8
1488 Female, age 94, right hemisphere 92.3
1490 Female, age 85, right hemisphere 87.5
1487 Female, age 94, left hemisphere 86.3
1489 Female, age 85, left hemisphere 82.2
1482 Male, age 61, left hemisphere 49.5
1485 Male, age 74, left hemisphere 39.4
1486 Male, age 74, right hemisphere 38.7
1483 Male, age 75, left hemisphere 28.9
1492 Female, age 67, right hemisphere 26.6
1491 Female, age 67, left hemisphere 26.2
1484 Male, age 75, right hemisphere 23.5
Orbitofrontal gyrus, posterior
nTPM: 68.1
1536 Female, age 94, left hemisphere 132.9
1537 Female, age 94, right hemisphere 115.7
1538 Female, age 85, left hemisphere 103.0
1539 Female, age 85, right hemisphere 80.2
1532 Male, age 61, right hemisphere 64.3
1531 Male, age 61, left hemisphere 64.1
1535 Male, age 74, left hemisphere 55.5
1533 Male, age 75, left hemisphere 52.2
1534 Male, age 75, right hemisphere 30.2
1540 Female, age 67, left hemisphere 27.7
1541 Female, age 67, right hemisphere 23.2
Subcallosal gyrus
nTPM: 62.4
1558 Female, age 85, left hemisphere 128.1
1559 Female, age 85, right hemisphere 115.4
1557 Female, age 94, right hemisphere 82.8
1551 Male, age 61, right hemisphere 74.7
1556 Female, age 94, left hemisphere 71.0
1554 Male, age 74, left hemisphere 55.5
1555 Male, age 74, right hemisphere 44.9
1552 Male, age 75, left hemisphere 39.1
1561 Female, age 67, right hemisphere 35.6
1550 Male, age 61, left hemisphere 35.3
1553 Male, age 75, right hemisphere 34.4
1560 Female, age 67, left hemisphere 32.1
Superior frontal gyrus
nTPM: 64.4
1569 Female, age 85, left hemisphere 106.9
1568 Female, age 94, right hemisphere 94.2
1567 Female, age 94, left hemisphere 89.0
1570 Female, age 85, right hemisphere 81.1
1563 Male, age 61, right hemisphere 62.5
1562 Male, age 61, left hemisphere 56.2
1565 Male, age 75, right hemisphere 43.9
1566 Male, age 74, right hemisphere 41.5
1564 Male, age 75, left hemisphere 36.8
1571 Female, age 67, right hemisphere 32.2
Temporal cortex
nTPM: 66.3
1595 Female, age 94, right hemisphere 103.2
1596 Female, age 85, right hemisphere 95.4
1594 Female, age 94, left hemisphere 83.6
1590 Male, age 61, right hemisphere 64.5
1592 Male, age 74, left hemisphere 51.3
1593 Male, age 74, right hemisphere 42.2
1591 Male, age 75, right hemisphere 23.6
Ventrolateral prefrontal cortex
nTPM: 55.0
1454 Female, age 94, left hemisphere 94.6
1455 Female, age 85, right hemisphere 92.0
1452 Male, age 74, left hemisphere 49.2
1453 Male, age 74, right hemisphere 47.0
1457 Female, age 67, right hemisphere 42.1
1451 Male, age 75, right hemisphere 36.4
1456 Female, age 67, left hemisphere 23.4
Ventromedial prefrontal cortex
nTPM: 79.5
1436 Female, age 85, left hemisphere 163.1
1437 Female, age 85, right hemisphere 114.5
1435 Female, age 94, right hemisphere 113.3
1432 Male, age 61, left hemisphere 55.7
1433 Male, age 61, right hemisphere 52.1
1434 Male, age 75, right hemisphere 35.1
1438 Female, age 67, left hemisphere 22.4

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 190.7
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 144.5
Samples: 233

Max nTPM: 332.2
Min nTPM: 52.5
Std nTPM: 48.3
Median nTPM: 139.0
GTEX-13N1W-0011-R3a-SM-5MR5E 70-79 years, male 332.2
GTEX-13O3O-0011-R3b-SM-5KM3R 60-69 years, female 286.3
GTEX-1O9I2-0011-R3b-SM-F648O 50-59 years, male 254.4
GTEX-14BIM-0011-R3b-SM-5S2RL 60-69 years, female 254.0
GTEX-N7MS-0011-R3a-SM-33HC6 60-69 years, male 253.6
GTEX-P44H-0011-R3A-SM-D3L8E 40-49 years, male 249.5
GTEX-13X6K-0011-R3b-SM-5PNUD 60-69 years, female 243.4
GTEX-1GN73-0011-R3b-SM-9QEIL 60-69 years, male 243.0
GTEX-12WSI-0011-R3a-SM-GJ3QB 50-59 years, male 241.3
GTEX-12WSM-0011-R3b-SM-5LZWI 60-69 years, male 239.9
GTEX-RNOR-0011-R3A-SM-5SI8E 50-59 years, female 239.6
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Brain - Cortex
Average nTPM: 190.7
Samples: 270

Max nTPM: 359.5
Min nTPM: 65.6
Std nTPM: 53.6
Median nTPM: 191.6
GTEX-1GN73-3126-SM-9KNTY 60-69 years, male 359.5
GTEX-1H1ZS-3026-SM-9KNUJ 70-79 years, male 336.1
GTEX-1HSMO-3026-SM-A9G3F 60-69 years, male 322.5
GTEX-12WSF-3126-SM-6M478 70-79 years, male 307.2
GTEX-1H3NZ-3026-SM-9JGHW 60-69 years, male 307.1
GTEX-12WSC-3026-SM-5GCNF 50-59 years, male 304.3
GTEX-11DXW-1126-SM-5H12Q 40-49 years, male 290.0
GTEX-ZYFD-3026-SM-5E44C 50-59 years, male 288.0
GTEX-12WSH-3026-SM-5CVNI 50-59 years, male 283.7
GTEX-13O3O-3126-SM-5KM3H 60-69 years, female 280.5
GTEX-Z93S-2926-SM-57WB9 50-59 years, male 276.4
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Brain - Frontal Cortex (BA9)
Average nTPM: 158.9
Samples: 269

Max nTPM: 299.9
Min nTPM: 43.3
Std nTPM: 47.5
Median nTPM: 156.4
GTEX-12WSF-0011-R10a-SM-5LZVH 70-79 years, male 299.9
GTEX-11H98-0011-R10b-SM-5NQ98 50-59 years, male 294.3
GTEX-13SLX-0011-R10a-SM-5P9HV 50-59 years, female 285.1
GTEX-131XH-0011-R10a-SM-5EGLJ 50-59 years, male 277.3
GTEX-16XZZ-0011-R10b-SM-7LT91 60-69 years, male 267.0
GTEX-14PN4-0011-R10b-SM-69LP2 50-59 years, male 261.5
GTEX-13N1W-0011-R10b-SM-5MR4H 70-79 years, male 260.3
GTEX-14ASI-0011-R10b-SM-5S2VZ 60-69 years, male 259.0
GTEX-13CZV-0011-R10b-SM-5LZYD 60-69 years, male 253.8
GTEX-13OW6-0011-R10a-SM-5L3HE 50-59 years, male 253.3
GTEX-1EX96-0011-R10b-SM-CE6QR 50-59 years, male 250.7
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 166.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 88.3
FF:10163-103B1 76 years, female 88.3
Postcentral gyrus
Scaled Tags Per Million: 139.3
FF:10032-101E5 44-52 years, mixed 139.3
Frontal lobe
Scaled Tags Per Million: 146.1
FF:10040-101F4 32-61 years, mixed 146.1
Insula
Scaled Tags Per Million: 154.9
FF:10039-101F3 20-68 years, mixed 154.9
Medial frontal gyrus
Scaled Tags Per Million: 123.0
FF:10150-102I6 76 years, female 123.0
Medial temporal gyrus
Scaled Tags Per Million: 126.3
FF:10183-103D3 60 years, female 132.7
FF:10156-103A3 76 years, female 120.0
Occipital lobe
Scaled Tags Per Million: 129.1
FF:10076-102A4 27 years, male 129.1
Occipital pole
Scaled Tags Per Million: 166.6
FF:10036-101E9 22-68 years, mixed 166.6
Paracentral gyrus
Scaled Tags Per Million: 132.0
FF:10035-101E8 22-69 years, mixed 132.0
Parietal lobe
Scaled Tags Per Million: 116.3
FF:10171-103B9 60 years, female 118.6
FF:10034-101E7 35-89 years, mixed 115.6
FF:10157-103A4 76 years, female 114.6
Temporal lobe
Scaled Tags Per Million: 135.6
FF:10031-101E4 32-61 years, mixed 135.6

CEREBRAL CORTEX - Pig RNA-seqi
Max subtype nTPMi 157.6
Pig sample Sample description nTPM
Occipital cortex
nTPM: 111.2
Samples: 4

Max nTPM: 136.9
Min nTPM: 91.1
Sample A Female 101.6
Sample B Female 136.9
Sample C Male 115.1
Sample D Male 91.1
Retrosplenial cortex
nTPM: 122.5
Samples: 4

Max nTPM: 153.1
Min nTPM: 99.8
Sample A Female 109.4
Sample B Female 99.8
Sample C Male 153.1
Sample D Male 127.8
Cingulate cortex
nTPM: 125.2
Samples: 4

Max nTPM: 142.7
Min nTPM: 106.7
Sample A Female 106.7
Sample B Female 119.4
Sample C Male 142.7
Sample D Male 131.9
Insular cortex
nTPM: 109.5
Samples: 4

Max nTPM: 120.9
Min nTPM: 98.1
Sample A Female 120.9
Sample B Female 99.9
Sample C Male 119.2
Sample D Male 98.1
Motor cortex
nTPM: 121.4
Samples: 4

Max nTPM: 150.4
Min nTPM: 90.1
Sample A Female 150.4
Sample B Female 117.9
Sample C Male 127.1
Sample D Male 90.1
Prefrontal cortex
nTPM: 157.6
Samples: 4

Max nTPM: 232.2
Min nTPM: 95.8
Sample A Female 232.2
Sample B Female 153.1
Sample C Male 149.4
Sample D Male 95.8
Somatosensory cortex
nTPM: 112.6
Samples: 3

Max nTPM: 115.9
Min nTPM: 110.6
Sample B Female 115.9
Sample C Male 111.2
Sample D Male 110.6
Temporal cortex
nTPM: 112.7
Samples: 4

Max nTPM: 136.4
Min nTPM: 92.2
Sample A Female 100.1
Sample B Female 136.4
Sample C Male 122.0
Sample D Male 92.2

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 38.3
Mouse sample Sample description nTPM
Occipital cortex
nTPM: 37.2
Samples: 4

Max nTPM: 40.7
Min nTPM: 33.2
Sample A Male 38.1
Sample B Male 40.7
Sample C Female 36.8
Sample D Female 33.2
Frontal cortex
nTPM: 35.5
Samples: 4

Max nTPM: 38.4
Min nTPM: 33.9
Sample A Male 38.4
Sample B Male 34.6
Sample C Female 35.0
Sample D Female 33.9
Retrosplenial and cingulate cortex
nTPM: 38.4
Samples: 4

Max nTPM: 41.4
Min nTPM: 35.5
Sample A Male 39.6
Sample B Male 41.4
Sample C Female 36.9
Sample D Female 35.5
Somatosensory cortex
nTPM: 37.0
Samples: 4

Max nTPM: 40.7
Min nTPM: 32.5
Sample A Male 38.1
Sample B Male 36.6
Sample C Female 32.5
Sample D Female 40.7

CEREBRAL CORTEX - Allen Mouse ISHi
Max subtype Expression energyi 13.4
Allen experiment id Experiment description Expression energy
Cerebral cortex
Expression energy: 13.4
73817931 Antisense, RP_051214_01_A02, Mouse strain C57BL/6J (56 days, male) 14.6
385781 Antisense, RP_040625_01_E09, Mouse strain C57BL/6J (56 days, male) 12.2

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