The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Hepatocytes displayed moderate cytoplasmic positivity. Gall bladder and Leydig cells of testis showed nuclear staining. Remaining normal tissues were mainly negative.
Most normal tissues displayed weak to moderate cytoplasmic staining and occasional nuclear positivity. Strong staining was observed in gastrointestinal tract, hepatocytes, breast glands, epididymis, prostate and astrocytes. Mesenchymal cells were negative.
A subset of adrenal glandular cells displayed strong cytoplasmic and membranous while Leydig cells displayed strong membranous staining. Strong cytoplasmic staining was observed in endocrine cells in stomach. Respiratory epithelia and Purkinje cells showed weak to moderate immunoreactivity. Remaining normal cells were negative.
Most normal tissues showed weak to moderate cytoplasmic staining with additional nuclear positivity in several cases. Soft tissues, lung, glial cells, bile ducts and hematopoietic cells were negative.
Most normal tissues displayed weak to moderate nuclear positivity with additional cytoplasmic staining in a few cases. Strong cytoplasmic immunoreactivity was observed in Purkinje cells and heart myocytes. Lung, skin, placenta, breast, prostate, spleen, hematopoietic cells, smooth muscle cells and soft tissues were negative.