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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
No data
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.
Scroll down to view mRNA expression data in more detail.
The MS-based protein data details section shows detailed information about the individual samples used for the relative protein abundance measurements.
Intensity values provides a relative protein abundance comparable between different genes and samples. All samples comes from one female donor. Median detection value represents the tissue for specificity and distribution categories. Protein detection is defined as a non-missing intensity value, and protein values are set to missing for a tissue if more than half of its replicates lacked a measurement for that protein.
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
3623.4
Female, age 60
Spleen sample 236 nTPM: 3579.9
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Male, age 17
Spleen sample 237 nTPM: 4621.7
Cell types%
Lymphocytes:
40
Macrophages:
35
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
5
Male, age 20
Spleen sample 238 nTPM: 5026.5
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
5
Other cell types:
10
Female, age 19
Spleen sample 239 nTPM: 1802.5
Cell types%
Lymphocytes:
40
Macrophages:
30
Endothelial cells:
15
Fibroblasts:
10
Other cell types:
5
Female, age 65
Spleen sample 378 nTPM: 3086.3
Cell types%
Lymphocytes:
35
Macrophages:
30
Endothelial cells:
20
Fibroblasts:
10
Other cell types:
5
SPLEEN - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
6752.2
GTEx sample id
Sample description
nTPM
Spleen Average nTPM: 6752.2
Samples: 277
Max nTPM: 42926.3
Min nTPM: 187.6
Std nTPM: 6296.6
Median nTPM: 4877.9
The Human Protein Atlas project is funded
