< No: 39

Interaction Section

The interactions of a protein can give valuable clues about its functions and locations. The Interaction section displays data for protein-protein as well as metabolic interaction networks. The protein-protein interaction networks displayed are extendable and interactive and can be integrated with other data to highlight proteins according to custom made filters or pre-selected features such as subcellular location or tissue specificity. The metabolic maps enables exploration of protein function and tissue-specific gene expression in the context of the human metabolic network while the metabolic summary describes the metabolic subsystems/pathways, cellular compartments, and number of reactions associated with each protein.

Key publications

- Orchard S et al., The MIntAct project--IntAct as a common curation platform for 11 molecular interaction databases. Nucleic Acids Res. (2014)
PubMed: 24234451 DOI: 10.1093/nar/gkt1115
- Robinson JL et al., An atlas of human metabolism. Sci Signal. (2020)
PubMed: 32209698 DOI: 10.1126/scisignal.aaz1482

Figure legend: The protein-protein interaction network for the gene A1CF highlighted according to subcellular location. More information about the network members is shown using mouse-over.

Key facts

  • 11351 proteins has protein-protein interaction data
  • 2912 proteins has metabolic pathway data