Leukemia

The upper left dot plot(s) shows the consistency between the cancer type related cell lines and their corresponding TCGA disease cohort based on Spearman correlation and normalized enrichment score (NES). In the lower left is a list of the cell lines ranked according to their similarity to the cancer type. By clicking on a cell line in the dot plot or in the ranked list lollipop plots showing the activity of cancer-related pathways inferred using PROGENy and CytoSig cytokines for that particular cell line will be displayed. For more details about the analysis see Methods summary and information about all cell lines can be found here.

Acute Myeloid Leukemia (LAML)

Explore the disease cohort in TCGA

Ranking	Cell line	Corr	NES
1	Kasumi-6	0.83	1.96
2	MOLM-6	0.84	1.9
3	KO52	0.83	1.99
4	MUTZ-3	0.83	1.89
5	GDM-1	0.82	1.95
6	Kasumi-1	0.82	1.87
6	Mono-Mac-1	0.81	1.87
8	OCI-AML-5	0.81	1.86
9	KG-1	0.83	1.83
10	OCI-AML-2	0.81	1.84
11	SKM-1	0.8	1.85
12	SIG-M5	0.8	1.84
13	NOMO-1	0.8	1.86
14	P31/FUJ	0.8	1.83
15	AML-193	0.81	1.8
15	Mono-Mac-6	0.81	1.77
17	UKE-1	0.81	1.74
18	EoL-1	0.81	1.74
19	CMK	0.8	1.8
19	Loucy	0.8	1.84
21	U-937	0.81	1.74
22	ME-1 [Human leukemia	0.82	1.69
23	THP-1	0.8	1.77
24	MOLT-13	0.79	1.85
25	NALM-1	0.8	1.78
26	HNT-34	0.81	1.71
26	NB4	0.81	1.7
28	HL-60	0.82	1.67
29	MOLT-16	0.79	1.83
30	PLB-985	0.8	1.71
31	MHH-CALL-2	0.79	1.77
32	EM-2	0.81	1.67
33	MOLM-13	0.8	1.68
33	SET-2	0.79	1.76
35	MHH-CALL-4	0.8	1.71
36	MV4-11	0.8	1.69
37	SEM	0.79	1.76
38	PL-21	0.8	1.66
39	SKNO-1	0.8	1.6
40	HEL	0.79	1.7
41	LAMA-84	0.79	1.68
41	M-07e	0.8	1.67
41	MHH-CALL-3	0.79	1.73
44	KCL-22	0.79	1.71
45	TF-1	0.78	1.7
45	Kasumi-2	0.78	1.7
47	Ku812	0.8	1.6
48	KE-37	0.77	1.73
49	CML-T1	0.77	1.79
50	ML-2	0.79	1.61
50	MOLM-16	0.79	1.57
52	NCO2	0.79	1.6
53	SUP-B15	0.79	1.56
53	HEL 92.1.7	0.78	1.63
55	JK-1	0.78	1.61
56	P12-Ichikawa	0.77	1.65
57	NALM-19	0.79	1.56
57	PF-382	0.77	1.71
59	RPMI-8402	0.77	1.63
60	MOLT-3	0.77	1.62
61	OCI-AML-3	0.79	1.55
62	MUTZ-5	0.79	1.56
63	HMC-1	0.77	1.62
64	F-36P	0.78	1.58
65	TALL-1 [Human adult	0.77	1.58
66	CCRF-SB	0.77	1.62
67	RCH-ACV	0.78	1.54
67	Peer	0.78	1.54
69	JURKAT	0.77	1.61
70	JURL-MK1	0.77	1.58
71	Jurkat E6.1	0.77	1.59
71	KOPN-8	0.78	1.45
73	JVM-3	0.75	1.62
73	NALM-6	0.77	1.53
75	REH	0.78	1.43
76	ALL-SIL	0.77	1.5
77	MEC-1	0.77	1.53
78	DND-41	0.77	1.49
79	BDCM	0.76	1.53
80	BV-173	0.77	1.4
81	OCI-M1	0.77	1.45
81	MEG-01	0.77	1.53
83	MOLT-4	0.77	1.34
84	SUP-T11	0.76	1.5
84	HPB-ALL	0.75	1.53
86	SUP-T1	0.76	1.49
87	JM-1	0.77	1.37
88	697	0.76	1.43
88	OCI-M2	0.75	1.47
90	RS4;11	0.75	1.31
91	K-562	0.74	1.3
92	KYO-1	0.73	1.25
93	HAP1	0.7	0.82

CELL LINE DATA
Cell line	Kasumi-6
Patient:	Male, 64
Disease subtype:	Acute Myelogenous Leukemia (AML), M2 (Myeloblastic)
Primary/metastasis:	Primary
Sample collection site:	Haematopoietic and lymphoid tissue
Cellosaurus:	CVCL_0614
PROGENy

CytoSig