The open access resource for human proteins
Search for specific genes/proteins or explore the eight different resources
ERN1: A Peculiar Regulator of the Unfolded Protein Response
This week, we explore a fascinating protein that regulates the unfolded protein response (UPR) in eukaryotic cells in an unusual manner - by sensing the accumulation of unfolded proteins in the endoplasmic reticulum (ER) lumen and conveying this information to the nucleus.
Wed, 27 Nov 2024
Multiplex tissue image of the month - BPIFB2 in salivary gland
The mucus acinus-specific expression pattern of BPI fold containing family B member 2 (gene: BPIFB2) in salivary gland is highlighted by multiplex immunohistochemistry (mIHC/IF).
Wed, 4 Dec 2024
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TISSUE
Protein and RNA profiles in tissues based on antibodies and transcriptomics
BRAIN
Protein and spatial RNA profiles in brain based on microdissected regions
SINGLE CELL
RNA profiles in tissues and immune cells from single cell and bulk deconvolution transcriptomics
SUBCELLULAR
Spatial, subcellular protein profiles in human cells based on antibodies
CANCER
Protein and RNA profiles in human cancers based on antibodies and transcriptomics
BLOOD
Blood protein levels in health and disease based on antibodies and MS
CELL LINE
RNA profiles in human cell lines with best models for human cancers
STRUCTURE & INTERACTION
3D-structures, protein interaction networks and metabolic pathways with highlight options


The transcription factor landscape

The human secretome
 

Multiplex tissue profiling
 

The human protein classes
 

The Disease Blood Atlas
 


The Human Membrane Proteome

The spatial transcriptomics of the brain

3-D structures of the human proteins

Cilia and basal bodies
 

Sperm
 

Evidence of the human protein-coding genes


The tissue and cell specific proteome

The house-keeping proteome

The right cell line for your experiment

The druggable proteome
 

The cancer proteome
 
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.