Diffuse-synaptic immunostaining is observed in distinct regions of the brain with various signal intensities. The distribution of the immunostaining is highly restricted to certain regions.
In the olfactory bulb, diffuse-synaptic staining is noticed in the external plexiform-, glomerular- and olfactory nerve layers. In the forebrain, moderate-strong staining is noticed in the septum (lateral-medial), anterior and tuberal hypothalamus, globus pallidus, the entire thalamus and hippocampus. Weak-moderate staining is noticed in the neocortex layer V, the retrosplenial granular cortex, entorhianl and piriform cortices.
In the brainstem, the moderate-strong diffuse synaptic staining is restricted to multiple (but not all) nuclei).
Positive cells and structuresi
Manually selected location of the protein positivity, observed by immunofluorescence staining in mouse brain.
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The Human Protein Atlas project is funded
