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TISSUE PRIMARY DATA KIDNEY Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND AMYGDALA APPENDIX BASAL GANGLIA BLOOD VESSEL BONE MARROW BREAST BRONCHUS CEREBELLUM CEREBRAL CORTEX CERVIX CHOROID PLEXUS COLON
DUODENUM ENDOMETRIUM EPIDIDYMIS ESOPHAGUS FALLOPIAN TUBE GALLBLADDER HEART MUSCLE HIPPOCAMPAL FORMATION HYPOTHALAMUS KIDNEY LIVER LUNG LYMPH NODE MIDBRAIN
NASOPHARYNX ORAL MUCOSA OVARY PANCREAS PARATHYROID GLAND PITUITARY GLAND PLACENTA PROSTATE RECTUM RETINA SALIVARY GLAND SEMINAL VESICLE SKELETAL MUSCLE SKIN
SMALL INTESTINE SMOOTH MUSCLE SOFT TISSUE SPINAL CORD SPLEEN STOMACH TESTIS THYMUS THYROID GLAND TONGUE TONSIL URINARY BLADDER VAGINA
ANTIBODIES
AND
VALIDATION
Dictionary
Kidney
Tissue proteome
Kidney
Tissue methods
KIDNEY - Expression summary
Protein expression
Kidneyi

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

h
m
l
n
Bowman's capsule: Not detected
Cells in glomeruli: Not detected
Collecting ducts: Not detected
Distal tubules: Not detected
Proximal tubules (cell body): Not detected
Proximal tubules (microvilli): High
Protein profiling
Multiplex tissuei

A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.

Microvilli staining in proximal tubules.

RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:785.7 nTPM
HPA:785.7 nTPM
GTEx:346.9 nTPM
FANTOM5:281.5 Scaled Tags Per Million
KIDNEY - SINGLE CELL RNA EXPRESSION
Explore single cell type data

KIDNEY - Multiplex stainingi

Antibody localization in the annotated cell types/states/structures of the current human tissue is reported as main/additional locations, percent overlap between the antibody and cell type/state/structure-specific markers, and, when applicable also subcellular localization. The scores are based on multiplex immunohistochemistry profiling in selected tissues.

Main locations are characterized by a high overlap between the antibody and the cell type/state-specific marker combined with strong antibody signal intensity, while additional locations are characterized by lower overlap and weaker antibody signal intensity.

The antibody of interest is reported in green, while cell types/states/structures are reported in various other colors, and DAPI (marks nucleus) is reported in blue. Colors can be toggled on and off by clicking on the name of the cell type/state of interest, “Antibody” or “DAPI”. To toggle between the different tissue samples, click on the miniature images at the right bottom corner of the main image. The miniature images appear upon hovering the mouse over that area.

- Antibody HPA056027
Main location Proximal tubules
No antibody overlap
Antibody overlap>75%
LocationMicrovilli
No antibody overlap
No antibody overlap
No antibody overlap

KIDNEY - Antibody stainingi

Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.

Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.

Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)

Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts

Antibody HPA045046Antibody HPA056027
Bowman's capsule -Not detected
Cells in glomeruli Not detectedNot detected
Cells in tubules High-
Collecting ducts -Not detected
Distal tubules -Not detected
Proximal tubules (cell body) -Not detected
Proximal tubules (microvilli) -High





KIDNEY - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Average nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

785.7
overview
Female, age 58
Kidney sample 55
nTPM: 672.6
Cell types%
Cells in tubules:
60

Cells in glomeruli:
20

Fibroblasts:
5

Other cell types:
15

overview
Female, age 67
Kidney sample 56
nTPM: 641.8
Cell types%
Cells in tubules:
70

Cells in glomeruli:
15

Fibroblasts:
10

Other cell types:
5

overview
Female, age 55
Kidney sample 57
nTPM: 212.1
Cell types%
Cells in tubules:
80

Cells in glomeruli:
10

Fibroblasts:
5

Other cell types:
5

overview
Male, age 46
Kidney sample 58
nTPM: 772
Cell types%
Cells in tubules:
60

Cells in glomeruli:
25

Fibroblasts:
5

Other cell types:
10

overview
Female, age 57
Kidney sample 358
nTPM: 647.1
Cell types%
Cells in tubules:
60

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
20

overview
Male, age 78
Kidney sample 377
nTPM: 559.4
Cell types%
Cells in tubules:
65

Cells in glomeruli:
10

Fibroblasts:
5

Other cell types:
20

overview
Male, age 73
Kidney sample 380
nTPM: 2320.5
Cell types%
Cells in tubules:
60

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
20

overview
Female, age 59
Kidney sample 394
nTPM: 710.7
Cell types%
Cells in tubules:
65

Cells in glomeruli:
10

Fibroblasts:
10

Other cell types:
15

overview
Female, age 48
Kidney sample 414
nTPM: 535.7
Cell types%
Cells in tubules:
60

Cells in glomeruli:
5

Fibroblasts:
10

Other cell types:
25


KIDNEY - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

346.9
GTEx sample id Sample description nTPM
Kidney - Cortex
Average nTPM: 346.9
Samples: 104

Max nTPM: 1025.5
Min nTPM: 12.7
Std nTPM: 208.3
Median nTPM: 346.2
GTEX-1NV8Z-2226-SM-EXOJ2 60-69 years, male 1025.5
GTEX-T6MN-1826-SM-EXOHN 50-59 years, male 847.9
GTEX-Y5V5-1226-SM-EYYVP 60-69 years, female 793.4
GTEX-T5JC-1526-SM-4DM68 20-29 years, male 741.5
GTEX-13NYB-1726-SM-5N9G2 40-49 years, male 722.4
GTEX-1117F-2126-SM-GIN9G 60-69 years, female 700.7
GTEX-1RQEC-2426-SM-F2I1J 60-69 years, male 669.0
GTEX-13OW6-1826-SM-5N9F9 50-59 years, male 664.9
GTEX-14JG1-2326-SM-HAUZ5 40-49 years, male 647.7
GTEX-1HCVE-2126-SM-HL9UO 50-59 years, male 644.2
GTEX-1ICLY-2026-SM-GA913 50-59 years, male 628.1
GTEX-1BAJH-1826-SM-731DA 70-79 years, male 624.2
GTEX-QDT8-1726-SM-EYYV6 30-39 years, female 622.7
GTEX-14E6D-2526-SM-5YYA9 50-59 years, male 597.0
GTEX-1JMQJ-1726-SM-E9U4V 50-59 years, male 573.3
GTEX-15DCD-1926-SM-HAV33 70-79 years, female 572.7
GTEX-1H3NZ-2126-SM-9WPQ6 60-69 years, male 561.1
GTEX-QDVN-1726-SM-HL9TO 50-59 years, male 560.2
GTEX-Y5V6-2026-SM-5IFHO 60-69 years, male 560.2
GTEX-16MT8-1926-SM-7EPGL 60-69 years, female 550.2
GTEX-ZC5H-1726-SM-5HL7X 40-49 years, female 536.9
GTEX-1GF9W-1326-SM-7P8PX 60-69 years, male 527.1
GTEX-1GMR3-2426-SM-7MXV2 40-49 years, male 514.4
GTEX-13FHP-2126-SM-GIN8J 50-59 years, male 490.0
GTEX-NFK9-1826-SM-HL9T3 40-49 years, male 488.9
GTEX-1KWVE-0826-SM-CXZKO 30-39 years, male 488.1
GTEX-1R9PO-1626-SM-E6CPT 60-69 years, female 478.7
GTEX-1I1GP-1926-SM-CNNQU 50-59 years, male 436.1
GTEX-P4QS-1126-SM-3NMD5 60-69 years, male 425.7
GTEX-1HBPI-2026-SM-CE6RZ 50-59 years, male 424.5
GTEX-15DYW-2026-SM-6AJBD 60-69 years, female 423.4
GTEX-1JJE9-1026-SM-HL9TH 70-79 years, male 422.3
GTEX-11OF3-1326-SM-5N9FJ 60-69 years, male 421.8
GTEX-1GF9V-1926-SM-9JGHE 60-69 years, male 419.3
GTEX-1E2YA-1626-SM-7MGXS 50-59 years, male 417.6
GTEX-14PJ2-1826-SM-HL9UB 50-59 years, male 411.3
GTEX-13O1R-2526-SM-5N9FW 60-69 years, male 409.5
GTEX-15CHQ-2126-SM-6871M 60-69 years, male 405.6
GTEX-1JJ6O-2526-SM-AHZ3J 60-69 years, male 403.4
GTEX-1QAET-2126-SM-F2TBS 50-59 years, male 400.1
GTEX-REY6-1826-SM-EAZAT 60-69 years, male 391.5
GTEX-1JMLX-1526-SM-AHZ3N 50-59 years, male 389.9
GTEX-16XZZ-2226-SM-HAV34 60-69 years, male 380.5
GTEX-12WSG-0826-SM-5EQ5A 50-59 years, female 377.9
GTEX-14C5O-2026-SM-5YYB1 60-69 years, male 376.6
GTEX-17HHY-2326-SM-7KFSR 50-59 years, male 375.8
GTEX-1IKK5-0926-SM-A9G2U 60-69 years, male 374.6
GTEX-1HB9E-1826-SM-D4P33 50-59 years, male 364.7
GTEX-17F96-1926-SM-7MGWY 70-79 years, male 362.8
GTEX-1EKGG-2226-SM-7IGOA 60-69 years, male 355.9
GTEX-145MN-0326-SM-5QGQI 30-39 years, male 355.6
GTEX-1IL2V-1826-SM-ARU7R 70-79 years, male 352.9
GTEX-1PWST-2226-SM-EVR3G 70-79 years, male 339.5
GTEX-1O9I2-1926-SM-F2TBQ 50-59 years, male 339.4
GTEX-1GTWX-1826-SM-9QEHG 60-69 years, male 338.7
GTEX-1A8FM-2026-SM-7P8RN 50-59 years, female 327.0
GTEX-1GN1U-2126-SM-AHZ4J 50-59 years, female 323.3
GTEX-WL46-1926-SM-GNIN6 50-59 years, male 319.3
GTEX-1497J-0826-SM-5NQAJ 60-69 years, male 316.0
GTEX-1J1OQ-1426-SM-AHZ3P 40-49 years, female 315.8
GTEX-1JMPZ-1226-SM-ARU8Y 30-39 years, male 312.3
GTEX-1QP6S-1526-SM-EXUSG 40-49 years, male 299.3
GTEX-16Z82-2826-SM-HAUZZ 60-69 years, male 286.0
GTEX-1C6VQ-2326-SM-7IGN1 50-59 years, male 274.4
GTEX-13RTJ-2226-SM-5S2Q1 60-69 years, male 263.8
GTEX-XPVG-0526-SM-4B65N 50-59 years, male 262.9
GTEX-1HCU7-1826-SM-A9G2A 50-59 years, male 257.1
GTEX-13O3O-1726-SM-GJ3RL 60-69 years, female 243.6
GTEX-1K9T9-1826-SM-CXZK2 50-59 years, female 237.1
GTEX-14C39-2126-SM-664OH 40-49 years, male 235.4
GTEX-11GS4-2326-SM-5A5KS 60-69 years, male 230.0
GTEX-S33H-1426-SM-EZ6L7 30-39 years, male 220.4
GTEX-1LG7Y-2726-SM-D5OVW 50-59 years, male 220.0
GTEX-1N2EF-1426-SM-EXUSH 60-69 years, male 219.4
GTEX-ZDXO-0226-SM-4WKH7 60-69 years, male 214.6
GTEX-O5YV-1226-SM-EV795 60-69 years, female 214.2
GTEX-1JMQK-1926-SM-CJI3B 60-69 years, male 187.6
GTEX-13OVI-1126-SM-5KLZF 60-69 years, female 172.8
GTEX-1F48J-2226-SM-7MXTN 50-59 years, female 164.5
GTEX-ZLFU-0926-SM-5P9F8 40-49 years, male 157.1
GTEX-ZVZP-0926-SM-5GIDB 50-59 years, male 154.8
GTEX-147F4-2626-SM-5Q5CS 50-59 years, male 151.7
GTEX-1MUQO-2526-SM-E9TJN 60-69 years, male 143.4
GTEX-ZYFG-1626-SM-5GZYY 60-69 years, female 134.1
GTEX-1AX8Z-2326-SM-731CR 60-69 years, male 131.9
GTEX-17F97-1926-SM-7IGM4 50-59 years, male 131.3
GTEX-1399S-0526-SM-5IJG8 30-39 years, female 124.0
GTEX-1CB4J-1926-SM-7MGX8 60-69 years, male 117.4
GTEX-1H3VY-1926-SM-9JGHJ 50-59 years, male 114.0
GTEX-1N2DW-1826-SM-EAZ54 50-59 years, male 111.9
GTEX-ZYT6-2226-SM-5GIC9 30-39 years, male 102.1
GTEX-W5X1-1626-SM-H7OGO 40-49 years, female 92.1
GTEX-11TTK-1926-SM-5PNW8 60-69 years, female 84.2
GTEX-13OVL-1826-SM-5KLZR 50-59 years, male 81.2
GTEX-QLQW-1626-SM-CMKFE 30-39 years, male 74.4
GTEX-1A3MW-2226-SM-73KUX 60-69 years, female 55.1
GTEX-16XZY-1026-SM-HAV39 70-79 years, male 54.3
GTEX-13112-2126-SM-5GCO4 50-59 years, male 49.4
GTEX-12696-0926-SM-5FQTV 60-69 years, male 44.4
GTEX-RN64-1626-SM-48FD7 50-59 years, male 41.3
GTEX-ZE9C-1426-SM-4WKGM 60-69 years, male 23.7
GTEX-1OJC4-2326-SM-DTXA5 50-59 years, female 21.7
GTEX-ZXG5-2026-SM-HAUZV 60-69 years, male 20.5
GTEX-1LH75-1326-SM-F2I1R 50-59 years, female 12.7
Show allShow less
Kidney - Medulla
Average nTPM: 164.9
Samples: 11

Max nTPM: 642.6
Min nTPM: 17.6
Std nTPM: 194.8
Median nTPM: 55.4
GTEX-N7MS-1526-SM-HAUZP 60-69 years, male 642.6
GTEX-P4QS-1226-SM-HPAG8 60-69 years, male 392.0
GTEX-RU72-1926-SM-EAZ3F 50-59 years, female 336.7
GTEX-TKQ2-0626-SM-EZ6LB 50-59 years, male 140.5
GTEX-QEG4-1526-SM-GPRWK 30-39 years, male 92.9
GTEX-SIU8-1926-SM-H7OG4 50-59 years, male 55.4
GTEX-T5JC-1626-SM-EZ6KW 20-29 years, male 42.6
GTEX-R55E-2026-SM-EZ6L1 20-29 years, male 38.4
GTEX-T6MN-1926-SM-GOQYD 50-59 years, male 35.3
GTEX-S33H-1526-SM-GQ1CB 30-39 years, male 20.1
GTEX-QEG5-2026-SM-H6Q6I 20-29 years, male 17.6
Show allShow less

KIDNEY - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

281.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Kidney
Scaled Tags Per Million: 281.5
FF:10017-101C8 60,62,63 years, female 281.5

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