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  • SEPTIN3
EVOLUTIONARY PONS Show tissue menu
BRAIN74 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

40.211
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:158.6 nTPM
FANTOM5:97.6 Scaled Tags Per Million
Macaque:77.1 nTPM
Mouse:110.4 nTPM
Rat:143.1 nTPM
Pig:103.4 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity.

, antibody CAB017633
Pons mean intensity 40.211
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 19.111
Parabrachial nucleus 40.211
Principle sensory trigeminal nucleus 18.443
Locus coeruleus 32.593
Pontine nucleus 13.960
Vestibular nucleus 16.930
Pontine reticular nucleus, oral 20.181
Lateral lemniscus 11.852
Superior paraolivary nucleus 18.097

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

158.6
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 86.4
2301 Female, age 85, both hemispheres 112.2
1984 Male, age 76, both hemispheres 94.4
2090 Male, age 80, both hemispheres 73.1
2188 Female, age 91, both hemispheres 65.9
Dorsal cochlear nucleus
nTPM: 89.3
2058 Male, age 76, both hemispheres 99.7
2802 Male, age 74, right hemisphere 94.4
2370 Male, age 61, both hemispheres 91.0
2187 Female, age 91, both hemispheres 90.0
2378 Male, age 80, both hemispheres 71.5
Dorsal tegmental nucleus
nTPM: 85.0
2083 Male, age 80, both hemispheres 100.6
1936 Male, age 76, left hemisphere 92.8
2358 Male, age 61, both hemispheres 82.6
2326 Male, age 74, both hemispheres 64.0
Dorsolateral tegmental area
nTPM: 87.1
2141 Male, age 76, both hemispheres 127.4
2751 Female, age 85, both hemispheres 100.8
2654 Male, age 80, both hemispheres 93.4
2360 Male, age 74, both hemispheres 70.4
2337 Male, age 61, both hemispheres 43.3
Kolliker-Fuse nucleus
nTPM: 93.7
2163 Male, age 80, both hemispheres 100.0
2793 Female, age 91, left hemisphere 95.1
2315 Male, age 76, right hemisphere 86.0
Lateral lemniscal nuclei
nTPM: 137.7
2169 Male, age 76, both hemispheres 155.9
2036 Male, age 80, both hemispheres 147.9
2746 Female, age 85, left hemisphere 146.5
2453 Male, age 74, right hemisphere 145.5
2320 Female, age 91, left hemisphere 92.7
Lateral parabrachial nucleus
nTPM: 104.2
2139 Female, age 85, right hemisphere 167.0
2013 Male, age 80, both hemispheres 100.8
2790 Male, age 61, both hemispheres 85.9
2792 Male, age 76, both hemispheres 63.1
Lateral vestibular nucleus
nTPM: 93.4
2184 Male, age 76, both hemispheres 99.5
2311 Male, age 80, both hemispheres 87.4
Locus coeruleus
nTPM: 145.5
2123 Female, age 91, both hemispheres 178.3
2720 Male, age 74, both hemispheres 159.6
2788 Male, age 74, unknown 144.3
2014 Male, age 55, unknown 141.2
2162 Male, age 80, both hemispheres 135.4
2317 Female, age 72, unknown 131.7
1980 Male, age 76, both hemispheres 128.2
Medial parabrachial nucleus
nTPM: 99.6
2854 Male, age 80, both hemispheres 119.4
2786 Male, age 76, both hemispheres 102.6
2170 Female, age 91, both hemispheres 93.0
2463 Female, age 85, right hemisphere 91.6
2156 Male, age 61, both hemispheres 91.3
Medial periolivary nuclei
nTPM: 134.3
2171 Female, age 85, both hemispheres 212.9
2063 Male, age 76, both hemispheres 166.0
2791 Male, age 74, right hemisphere 123.6
2081 Male, age 80, both hemispheres 85.8
2458 Female, age 91, both hemispheres 83.1
Motor facial nucleus
nTPM: 137.3
2062 Male, age 76, both hemispheres 180.4
2327 Male, age 80, both hemispheres 153.3
2365 Male, age 74, right hemisphere 143.4
2697 Female, age 85, both hemispheres 137.2
2795 Female, age 91, both hemispheres 107.3
2126 Male, age 61, both hemispheres 102.5
Motor trigeminal nucleus
nTPM: 105.1
2079 Male, age 80, both hemispheres 132.0
2560 Male, age 74, both hemispheres 106.2
2309 Male, age 76, both hemispheres 105.8
2335 Male, age 61, both hemispheres 100.8
2321 Female, age 91, both hemispheres 80.9
Nuclei of the trapezoid body
nTPM: 152.8
2735 Female, age 85, both hemispheres 211.8
1983 Male, age 76, both hemispheres 168.2
2159 Male, age 61, both hemispheres 166.3
2166 Male, age 80, both hemispheres 115.6
2368 Female, age 91, both hemispheres 102.2
Nucleus raphe magnus
nTPM: 158.6
2172 Female, age 85, both hemispheres 235.7
2160 Male, age 61, both hemispheres 189.4
2455 Male, age 74, both hemispheres 165.5
2051 Male, age 76, both hemispheres 130.9
2328 Male, age 80, both hemispheres 128.7
2459 Female, age 91, both hemispheres 101.2
Paramedian reticular nucleus
nTPM: 120.8
2050 Female, age 85, both hemispheres 165.2
2313 Male, age 61, both hemispheres 133.9
2057 Male, age 80, both hemispheres 100.5
2052 Male, age 76, both hemispheres 83.9
Pedunculopontine tegmental nucleus
nTPM: 102.3
1921 Female, age 85, both hemispheres 126.1
2334 Male, age 80, both hemispheres 106.0
2338 Male, age 61, both hemispheres 74.6
Pontine nuclei
nTPM: 132.3
2787 Female, age 85, both hemispheres 224.6
1863 Male, age 55, unknown 155.1
2727 Male, age 61, right hemisphere 153.1
1968 Male, age 76, left hemisphere 149.0
2109 Female, age 72, unknown 123.4
2115 Male, age 80, left hemisphere 99.9
2454 Male, age 74, left hemisphere 80.4
2319 Female, age 91, both hemispheres 72.6
Pontine raphe nucleus
nTPM: 147.3
2122 Female, age 85, midline 158.8
2853 Male, age 76, midline 135.9
Posteroventral cochlear nucleus
nTPM: 79.1
2752 Female, age 85, both hemispheres 145.4
2070 Male, age 76, both hemispheres 92.6
2371 Male, age 61, both hemispheres 70.5
2341 Male, age 80, both hemispheres 60.9
2135 Female, age 91, both hemispheres 25.9
Principal sensory trigeminal nucleus
nTPM: 122.6
2158 Male, age 61, both hemispheres 161.6
2008 Male, age 80, left hemisphere 141.7
2324 Male, age 76, both hemispheres 97.5
2367 Female, age 91, left hemisphere 89.5
Reticular pontine nucleus, caudal
nTPM: 103.1
2332 Male, age 80, right hemisphere 142.2
2092 Male, age 76, both hemispheres 125.2
2457 Female, age 91, both hemispheres 80.3
2559 Male, age 74, both hemispheres 64.9
Reticular pontine nucleus, oral
nTPM: 108.3
2012 Female, age 85, both hemispheres 139.0
2167 Male, age 76, both hemispheres 115.4
2361 Male, age 74, both hemispheres 114.3
1939 Male, age 80, both hemispheres 101.2
2366 Female, age 91, both hemispheres 71.7
Reticulotegmental nucleus
nTPM: 112.0
2325 Male, age 76, both hemispheres 149.9
2333 Male, age 80, both hemispheres 103.3
2452 Male, age 74, both hemispheres 98.5
2322 Female, age 91, both hemispheres 96.3
Spinal trigeminal nucleus, oral
nTPM: 104.6
2737 Female, age 85, both hemispheres 110.1
1978 Male, age 76, both hemispheres 104.8
2164 Male, age 80, both hemispheres 98.8
Subcoeruleus area
nTPM: 111.8
2323 Female, age 91, left hemisphere 141.7
2089 Male, age 76, left hemisphere 132.4
1958 Male, age 80, both hemispheres 126.8
2369 Female, age 85, left hemisphere 79.9
2451 Male, age 74, both hemispheres 78.0
Superior olive
nTPM: 131.0
1875 Female, age 85, both hemispheres 177.7
2329 Male, age 80, right hemisphere 125.7
2364 Male, age 74, right hemisphere 124.8
2020 Male, age 76, both hemispheres 117.8
2561 Female, age 91, both hemispheres 109.3
Ventral periolivary nuclei
nTPM: 153.3
2130 Female, age 85, both hemispheres 212.7
2165 Male, age 80, both hemispheres 155.1
2794 Female, age 91, left hemisphere 129.4
2023 Male, age 76, both hemispheres 116.1
Ventrolateral tegmental area, A5 NE cell group
nTPM: 117.4
2449 Male, age 74, both hemispheres 153.2
2840 Female, age 85, both hemispheres 145.9
1959 Male, age 76, both hemispheres 133.6
2161 Male, age 80, both hemispheres 113.5
2359 Male, age 61, both hemispheres 87.2
2456 Female, age 91, both hemispheres 71.1

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

97.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 57.1
FF:10182-103D2 60 years, female 64.2
FF:10165-103B3 76 years, female 50.0
Pons
Scaled Tags Per Million: 97.6
FF:10033-101E6 18-54 years, mixed 97.6

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

77.1
Macaque sample Sample description nTPM
Pons
nTPM: 77.1
Samples: 2

Max nTPM: 83.7
Min nTPM: 70.5
Sample A 70.5
Sample B 83.7

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

103.4
Pig sample Sample description nTPM
Pons
nTPM: 103.4
Samples: 3

Max nTPM: 118.6
Min nTPM: 93.5
Sample A Female 118.6
Sample B Female 98.2
Sample C Male 93.5

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

110.4
Mouse sample Sample description nTPM
Pons
nTPM: 110.4
Samples: 4

Max nTPM: 127.2
Min nTPM: 98.2
Sample A 100.9
Sample B 127.2
Sample C 98.2
Sample D 115.1

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

143.1
Rat sample Sample description nTPM
Pons
nTPM: 143.1
Samples: 4

Max nTPM: 148.1
Min nTPM: 133.3
Sample A 148.1
Sample A 146.5
Sample A 133.3
Sample A 144.4

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