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UQCC1
HPA
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  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • SUBCELL

  • CANCER

  • BLOOD

  • CELL LINE

  • STRUCTURE

  • INTERACTION

  • UQCC1
SINGLE CELL EYE Show tissue menu
ADIPOSE TISSUE ADRENAL GLAND BLOOD BONE MARROW BRAIN BREAST COLON ENDOMETRIUM EPIDIDYMIS ESOPHAGUS
EYE FALLOPIAN TUBE HEART MUSCLE KIDNEY LIVER LUNG LYMPH NODE OVARY PANCREAS PITUITARY GLAND
PLACENTA PROSTATE RECTUM SALIVARY GLAND SKELETAL MUSCLE SKIN SMALL INTESTINE SPLEEN STOMACH TESTIS
THYMUS THYROID GLAND TONGUE URINARY BLADDER VASCULATURE
Single cell type
Tabula sapiens
Tissue cell type
SINGLE CELL TYPE TABULA SAPIENS CELL TYPE MARKERS
Cell types
Blood and immune cells
Specialized epithelial cells
Endothelial and mural cells
Neuronal cells
Mesenchymal cells
Pigment cells
Glial cells
Glandular epithelial cells
Methods
EYE DETAIL SUMMARY
SINGLE CELL TYPE - EYEi

RNA expression in the single cell type clusters identified in this tissue visualized by a UMAP plot (top) and a bar chart (bottom).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart below. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. The cells are colored according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%)

- The LEGEND shows RNA expression (nTPM) in each cell type cluster. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
Cluster filter:
 
Cluster Cell type Expression (nCPM)
0 70
c-0 B-cells
c-1 Corneal apical cells
c-2 T-cells (CD4+)
c-3 Venous ECs
c-4 B-cells
c-5 Rod photoreceptor cells
c-6 Corneal suprabasal epitheli...
c-7 T-cells (CD8+)
c-8 Fibroblasts
c-9 Conjunctival epithelial cel
c-10 B-cells
c-11 Conjunctival epithelial cel
c-12 Conjunctival epithelial cel
c-13 T-cells
c-14 Conjunctival epithelial cel
c-15 Fibroblasts
c-16 Conjunctival epithelial cel
c-17 Plasma cells
c-18 Resident macrophages
c-19 T-cells (CD4+)
c-20 Conjunctival epithelial cel
c-21 Corneal basal epithelial ce
c-22 Vascular smooth muscle cell
c-23 Limbal epithelial cells
c-24 Fibroblasts
c-25 Capillary ECs
c-26 T-cells (CD4+)
c-27 T-cells (CD8+)
c-28 Lymphatic endothelial cells
c-29 Monocytes
c-30 NK-cells
c-31 M2-like macrophages
c-32 Conjunctival Melaonocytes
c-33 Arterial ECs
c-34 NK-T-cells
c-35 Neutrophils
c-36 Transitional M2-like macrop...
c-37 Müller glia
c-38 Mast cells
c-39 B-cells
c-40 Pericytes
c-41 Serous acinar cells
c-42 Uveal Melanocytes
c-43 Mixed cell types
c-44 Corneal Fibroblasts
c-45 Bipolar cells
c-46 Conjunctival goblet cells
c-47 Schwann cells
c-48 Amacrine cells
c-49 Cone photoreceptor cells
c-50 Retinal pigment epithelia
c-51 Oligodendrocytes
c-52 Horizontal cells
SINGLE CELL TYPE - RETINAi

RNA expression in the single cell type clusters identified in this tissue visualized by a UMAP plot (top) and a bar chart (bottom).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart below. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. The cells are colored according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%)

- The LEGEND shows RNA expression (nTPM) in each cell type cluster. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
Cluster filter:
 
Cluster Cell type Expression (nCPM)
0 150
c-0 Rod photoreceptor cells
c-1 Müller glia
c-2 Rod photoreceptor cells
c-3 Rod photoreceptor cells
c-4 Rod photoreceptor cells
c-5 Rod photoreceptor cells
c-6 ON bipolar cells
c-7 Müller glia
c-8 Rod bipolar cells
c-9 OFF bipolar cells
c-10 Müller glia
c-11 Rod photoreceptor cells
c-12 OFF bipolar cells
c-13 Amacrine cells
c-14 Rod bipolar cells
c-15 Horizontal cells
c-16 Glycinergic amacrine cells
c-17 OFF bipolar cells
c-18 Cone photoreceptor cells
c-19 Rod bipolar cells
c-20 OFF bipolar cells
c-21 Rod bipolar cells
c-22 OFF bipolar cells
c-23 ON bipolar cells
c-24 ON bipolar cells
c-25 ON bipolar cells
c-26 Amacrine cells (SLC18A2+)
c-27 Glycinergic horizontal-like...
c-28 Starbust amacrine cells (Ch...
c-29 Retinal ganglion cells
c-30 Astrocytes
c-31 Microglia
c-32 Mural & Epithelial cells
SINGLE CELL TYPE TABULA SAPIENS - EYEi

RNA expression in the single cell type clusters identified in this tissue visualized by a UMAP plot and a bar chart. This window shows single cell expression data generated by the https://tabula-sapiens.sf.czbiohub.org/about#consortium, that also offers UMAP visualization and cell type clusters for each tissue sample: https://tabula-sapiens.sf.czbiohub.org/organs, here integrate offering easy comparison to the HPA cluster method of single cell types.

  • UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart below. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. The cells are colored according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%)

  • The LEGEND shows RNA expression (nTPM) in each cell type cluster. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 50
c-0 Conjunctival epithelial cel
c-1 Monocyte
c-2 Microglial cell
c-3 Eye photoreceptor cell
c-4 Muller cell
c-5 Fibroblast
c-6 T cell
c-7 Limbal stem cell
c-8 Retinal blood vessel endoth...
c-9 Epithelial cell of lacrimal...
c-10 Corneal keratocyte
c-11 B cell
c-12 Retinal pigment epithelial ...
c-13 Corneal epithelial cell
c-14 Limbal stromal cell
c-15 Melanocyte
c-16 Retinal bipolar neuron
c-17 Dendritic cell
c-18 Plasma cell
c-19 Lacrimal gland functional u...
c-20 Macrophage
c-21 Erythroid lineage cell
c-22 Radial glial cell
c-23 Ocular surface cell
c-24 Cd8-positive, alpha-beta t ...
c-25 Endothelial cell
c-26 Retina horizontal cell
c-27 Ciliary body
c-28 Cd4-positive, alpha-beta t ...
c-29 Mast cell
c-30 Adipocyte
c-31 Retinal ganglion cell
CELL TYPE MARKERSi

The heatmap in this section shows expression of the currently selected gene (on top) and well-known cell type markers in the different single cell type clusters of this tissue. The panel on the left shows which cell type each marker is associated with. Color-coding is based on cell type groups, each consisting of cell types with functional features in common.

Hover the mouse-pointer over the individual data points (squares) to see nTPM level and Z-score. Clicking on a gene name redirects to the corresponding gene page.

Z-score is when you normalize a variable such that the standard deviation is 1 and the mean is 0. Thus, all the genes are easier to compare, as they have the same center and distribution.

SINGLE CELL TYPE - EYE
SINGLE CELL TYPE - RETINA
TABULA SAPIENS
Max-norm
Z-score
Fraction of highest expression (≥1 nTPM)
log2(nTPM+1) z-score
Max-norm
Z-score
Fraction of highest expression (≥1 nTPM)
log2(nTPM+1) z-score
Max-norm
Z-score
Fraction of highest expression (≥1 nTPM)
log2(nTPM+1) z-score
 

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