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BETA
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EVOLUTIONARY PONS Show tissue menu
BRAIN74 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:93.8 nTPM
FANTOM5:83.5 Scaled Tags Per Million
Macaque:57.8 nTPM
Mouse:53.8 nTPM
Rat:64.5 nTPM
Pig:73.3 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

93.8
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 89.2
2301 Female, age 85, both hemispheres 96.3
1984 Male, age 76, both hemispheres 93.3
2090 Male, age 80, both hemispheres 85.1
2188 Female, age 91, both hemispheres 82.4
Dorsal cochlear nucleus
nTPM: 89.8
2802 Male, age 74, right hemisphere 104.7
2370 Male, age 61, both hemispheres 93.4
2378 Male, age 80, both hemispheres 85.9
2187 Female, age 91, both hemispheres 82.9
2058 Male, age 76, both hemispheres 82.1
Dorsal tegmental nucleus
nTPM: 91.0
2358 Male, age 61, both hemispheres 113.6
2083 Male, age 80, both hemispheres 94.9
2326 Male, age 74, both hemispheres 78.7
1936 Male, age 76, left hemisphere 76.8
Dorsolateral tegmental area
nTPM: 90.1
2337 Male, age 61, both hemispheres 113.7
2141 Male, age 76, both hemispheres 92.1
2654 Male, age 80, both hemispheres 90.0
2360 Male, age 74, both hemispheres 78.6
2751 Female, age 85, both hemispheres 75.9
Kolliker-Fuse nucleus
nTPM: 87.1
2793 Female, age 91, left hemisphere 98.1
2163 Male, age 80, both hemispheres 88.0
2315 Male, age 76, right hemisphere 75.1
Lateral lemniscal nuclei
nTPM: 88.5
2320 Female, age 91, left hemisphere 96.4
2036 Male, age 80, both hemispheres 90.3
2169 Male, age 76, both hemispheres 88.0
2746 Female, age 85, left hemisphere 87.5
2453 Male, age 74, right hemisphere 80.5
Lateral parabrachial nucleus
nTPM: 88.0
2790 Male, age 61, both hemispheres 104.0
2139 Female, age 85, right hemisphere 89.5
2013 Male, age 80, both hemispheres 82.9
2792 Male, age 76, both hemispheres 75.6
Lateral vestibular nucleus
nTPM: 89.7
2184 Male, age 76, both hemispheres 93.0
2311 Male, age 80, both hemispheres 86.5
Locus coeruleus
nTPM: 93.7
2720 Male, age 74, both hemispheres 111.1
2123 Female, age 91, both hemispheres 101.9
2317 Female, age 72, unknown 97.7
1980 Male, age 76, both hemispheres 92.7
2014 Male, age 55, unknown 92.4
2162 Male, age 80, both hemispheres 88.8
2788 Male, age 74, unknown 71.1
Medial parabrachial nucleus
nTPM: 89.1
2156 Male, age 61, both hemispheres 97.9
2463 Female, age 85, right hemisphere 87.9
2786 Male, age 76, both hemispheres 87.2
2170 Female, age 91, both hemispheres 86.5
2854 Male, age 80, both hemispheres 86.1
Medial periolivary nuclei
nTPM: 81.6
2063 Male, age 76, both hemispheres 87.5
2458 Female, age 91, both hemispheres 83.6
2081 Male, age 80, both hemispheres 82.3
2171 Female, age 85, both hemispheres 81.6
2791 Male, age 74, right hemisphere 73.0
Motor facial nucleus
nTPM: 91.1
2795 Female, age 91, both hemispheres 103.2
2062 Male, age 76, both hemispheres 95.3
2327 Male, age 80, both hemispheres 94.8
2126 Male, age 61, both hemispheres 90.4
2697 Female, age 85, both hemispheres 87.4
2365 Male, age 74, right hemisphere 75.5
Motor trigeminal nucleus
nTPM: 92.1
2321 Female, age 91, both hemispheres 108.4
2560 Male, age 74, both hemispheres 99.7
2335 Male, age 61, both hemispheres 90.2
2079 Male, age 80, both hemispheres 82.4
2309 Male, age 76, both hemispheres 79.6
Nuclei of the trapezoid body
nTPM: 85.2
1983 Male, age 76, both hemispheres 94.7
2368 Female, age 91, both hemispheres 88.6
2166 Male, age 80, both hemispheres 85.7
2735 Female, age 85, both hemispheres 82.8
2159 Male, age 61, both hemispheres 74.0
Nucleus raphe magnus
nTPM: 85.7
2328 Male, age 80, both hemispheres 98.7
2051 Male, age 76, both hemispheres 87.1
2172 Female, age 85, both hemispheres 87.1
2459 Female, age 91, both hemispheres 85.1
2160 Male, age 61, both hemispheres 78.4
2455 Male, age 74, both hemispheres 77.7
Paramedian reticular nucleus
nTPM: 75.5
2313 Male, age 61, both hemispheres 90.6
2057 Male, age 80, both hemispheres 76.2
2050 Female, age 85, both hemispheres 75.9
2052 Male, age 76, both hemispheres 59.5
Pedunculopontine tegmental nucleus
nTPM: 82.6
1921 Female, age 85, both hemispheres 84.2
2338 Male, age 61, both hemispheres 82.0
2334 Male, age 80, both hemispheres 81.5
Pontine nuclei
nTPM: 88.5
2787 Female, age 85, both hemispheres 104.5
2115 Male, age 80, left hemisphere 103.5
1968 Male, age 76, left hemisphere 95.9
1863 Male, age 55, unknown 87.5
2319 Female, age 91, both hemispheres 87.4
2109 Female, age 72, unknown 83.9
2727 Male, age 61, right hemisphere 77.8
2454 Male, age 74, left hemisphere 67.4
Pontine raphe nucleus
nTPM: 93.8
2853 Male, age 76, midline 100.7
2122 Female, age 85, midline 86.9
Posteroventral cochlear nucleus
nTPM: 83.1
2371 Male, age 61, both hemispheres 96.5
2341 Male, age 80, both hemispheres 86.0
2135 Female, age 91, both hemispheres 78.8
2070 Male, age 76, both hemispheres 77.9
2752 Female, age 85, both hemispheres 76.5
Principal sensory trigeminal nucleus
nTPM: 86.0
2324 Male, age 76, both hemispheres 89.9
2158 Male, age 61, both hemispheres 86.9
2367 Female, age 91, left hemisphere 86.6
2008 Male, age 80, left hemisphere 80.8
Reticular pontine nucleus, caudal
nTPM: 87.0
2332 Male, age 80, right hemisphere 93.8
2559 Male, age 74, both hemispheres 86.5
2092 Male, age 76, both hemispheres 84.3
2457 Female, age 91, both hemispheres 83.4
Reticular pontine nucleus, oral
nTPM: 82.6
2167 Male, age 76, both hemispheres 87.4
2366 Female, age 91, both hemispheres 84.3
1939 Male, age 80, both hemispheres 83.8
2361 Male, age 74, both hemispheres 82.7
2012 Female, age 85, both hemispheres 75.0
Reticulotegmental nucleus
nTPM: 92.2
2452 Male, age 74, both hemispheres 94.7
2333 Male, age 80, both hemispheres 92.5
2325 Male, age 76, both hemispheres 91.7
2322 Female, age 91, both hemispheres 89.9
Spinal trigeminal nucleus, oral
nTPM: 91.8
2164 Male, age 80, both hemispheres 97.7
2737 Female, age 85, both hemispheres 90.1
1978 Male, age 76, both hemispheres 87.4
Subcoeruleus area
nTPM: 84.6
2451 Male, age 74, both hemispheres 92.7
2089 Male, age 76, left hemisphere 87.2
2323 Female, age 91, left hemisphere 85.1
1958 Male, age 80, both hemispheres 82.4
2369 Female, age 85, left hemisphere 75.5
Superior olive
nTPM: 88.4
2561 Female, age 91, both hemispheres 107.5
2329 Male, age 80, right hemisphere 97.1
2020 Male, age 76, both hemispheres 85.9
1875 Female, age 85, both hemispheres 81.3
2364 Male, age 74, right hemisphere 70.1
Ventral periolivary nuclei
nTPM: 88.4
2130 Female, age 85, both hemispheres 104.6
2794 Female, age 91, left hemisphere 89.3
2165 Male, age 80, both hemispheres 85.1
2023 Male, age 76, both hemispheres 74.7
Ventrolateral tegmental area, A5 NE cell group
nTPM: 86.2
2456 Female, age 91, both hemispheres 97.2
2161 Male, age 80, both hemispheres 91.0
2359 Male, age 61, both hemispheres 84.2
2840 Female, age 85, both hemispheres 83.6
1959 Male, age 76, both hemispheres 81.5
2449 Male, age 74, both hemispheres 79.6

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

83.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 83.5
FF:10182-103D2 60 years, female 88.0
FF:10165-103B3 76 years, female 79.0
Pons
Scaled Tags Per Million: 53.5
FF:10033-101E6 18-54 years, mixed 53.5

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

57.8
Macaque sample Sample description nTPM
Pons
nTPM: 57.8
Samples: 2

Max nTPM: 63.7
Min nTPM: 51.8
Sample A 51.8
Sample B 63.7

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

73.3
Pig sample Sample description nTPM
Pons
nTPM: 73.3
Samples: 3

Max nTPM: 96.8
Min nTPM: 59.6
Sample A Female 96.8
Sample B Female 63.5
Sample C Male 59.6

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

53.8
Mouse sample Sample description nTPM
Pons
nTPM: 53.8
Samples: 4

Max nTPM: 60.4
Min nTPM: 48.1
Sample A 48.1
Sample B 60.4
Sample C 49.1
Sample D 57.6

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

64.5
Rat sample Sample description nTPM
Pons
nTPM: 64.5
Samples: 4

Max nTPM: 70.7
Min nTPM: 60.7
Sample A 60.7
Sample A 60.9
Sample A 65.7
Sample A 70.7

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