On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Glandular cells:
High
Protein profiling Multiplex tissuei
A summary of the protein localization in the current human tissue based on multiplex immunohistochemistry profiling in selected tissues is shown for genes where this analysis has been performed.
Cytoplasmic, membranous and nuclear staining in serous, mucus acini and small ducts.
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.
Scroll down to view mRNA expression data in more detail.
Antibody localization in the annotated cell types/states/structures of the current human tissue is reported as main/additional locations, percent overlap between the antibody and cell type/state/structure-specific markers, and, when applicable also subcellular localization. The scores are based on multiplex immunohistochemistry profiling in selected tissues.
Main locations are characterized by a high overlap between the antibody and the cell type/state-specific marker combined with strong antibody signal intensity,
while additional locations are characterized by lower overlap and weaker antibody signal intensity.
The antibody of interest is reported in green, while cell types/states/structures are reported in various other colors, and DAPI (marks nucleus) is reported in blue. Colors can be toggled on and off by clicking on the name of the cell type/state of interest, “Antibody” or “DAPI”. To toggle between the different tissue samples, click on the miniature images at the right bottom corner of the main image. The miniature images appear upon hovering the mouse over that area.
- Antibody HPA041650
Main location
Serous acini Mucus acini Small ducts
Antibody overlap
>75%
Location
Nuclear Plasma membrane
Antibody overlap
>75%
Location
Cytoplasm Nuclear Plasma membrane
No antibody overlap
No antibody overlap
Antibody overlap
75%-51%
Location
Cytoplasm Nuclear
SALIVARY GLAND - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.
Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)
Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts
Antibody HPA041650
Glandular cells
High
SALIVARY GLAND - PROTEINTALKS DB MS
Median intensity
6017
Sample
Intensity
Salivary gland_01
6016
Salivary gland_02
11607
Salivary gland_03
2064
Salivary gland_04
5578
Salivary gland_05
8799
SALIVARY GLAND - MANN MS
Median intensity
12306440
Replicate
Intensity
Salivary gland_01
12161737
Salivary gland_02
12306440
Salivary gland_03
18037805
SALIVARY GLAND - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
26.2
Female, age 68
Salivary gland sample 216 nTPM: 19.4
Cell types%
Glandular cells:
45
Ductal cells:
25
Adipocytes:
5
Other cell types:
25
Male, age 60
Salivary gland sample 217 nTPM: 29.4
Cell types%
Glandular cells:
55
Ductal cells:
20
Adipocytes:
5
Endothelial cells:
5
Other cell types:
15
Female, age 21
Salivary gland sample 218 nTPM: 29.7
Cell types%
Glandular cells:
55
Ductal cells:
15
Adipocytes:
5
Endothelial cells:
5
Other cell types:
20
SALIVARY GLAND - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
17.2
GTEx sample id
Sample description
nTPM
Minor Salivary Gland Average nTPM: 17.2
Samples: 181
Max nTPM: 47.3
Min nTPM: 2.0
Std nTPM: 8.0
Median nTPM: 15.9
GTEX-1A3MV-1726-SM-72D68
30-39 years, male
47.3
GTEX-13VXT-1726-SM-5IFF5
20-29 years, female
44.1
GTEX-1HCU7-0126-SM-C1YR3
50-59 years, male
38.2
GTEX-13OVL-2926-SM-5IFG3
50-59 years, male
36.3
GTEX-1LSNL-2626-SM-EV7AT
50-59 years, male
34.8
GTEX-13NYB-2426-SM-5IFF4
40-49 years, male
34.2
GTEX-ZLWG-2026-SM-DO11F
50-59 years, female
34.2
GTEX-1HFI6-2826-SM-GA91I
40-49 years, male
33.7
GTEX-11NV4-1926-SM-5N9D4
60-69 years, male
33.1
GTEX-X3Y1-1926-SM-4PQZO
40-49 years, male
31.5
GTEX-1RAZA-0626-SM-EAZ4H
20-29 years, male
31.1
GTEX-14PJN-1726-SM-69LO7
30-39 years, male
30.7
GTEX-1KD4Q-2526-SM-CXZKL
40-49 years, male
30.2
GTEX-ZLFU-2226-SM-EXUS7
40-49 years, male
30.2
GTEX-1RQED-2926-SM-HPAFT
60-69 years, male
29.9
GTEX-1IOXB-2826-SM-AHZ32
50-59 years, male
29.7
GTEX-1S5ZU-0926-SM-HPAEX
20-29 years, female
28.8
GTEX-YJ8A-1826-SM-GNTAB
20-29 years, male
28.4
GTEX-ZP4G-1926-SM-57WDZ
20-29 years, female
28.4
GTEX-13JVG-2926-SM-5J2N9
60-69 years, male
28.3
GTEX-15RJE-2726-SM-6LPJ1
40-49 years, male
28.3
GTEX-1KD5A-2226-SM-EV79U
50-59 years, male
28.0
GTEX-ZQUD-2126-SM-51MSY
30-39 years, male
28.0
GTEX-1C4CL-2026-SM-731EB
30-39 years, male
27.4
GTEX-15SHV-2226-SM-6M464
60-69 years, male
27.1
GTEX-1AMEY-1126-SM-72D79
30-39 years, female
26.5
GTEX-1LVA9-2526-SM-EVR5H
50-59 years, male
26.4
GTEX-1POEN-2226-SM-DPRXV
30-39 years, female
26.1
GTEX-1S5VW-1026-SM-HK797
60-69 years, male
26.1
GTEX-1B8KZ-1726-SM-73KV7
50-59 years, male
25.9
GTEX-1GZ2Q-2526-SM-9KNVW
40-49 years, male
25.5
GTEX-14B4R-1426-SM-5Q5CG
30-39 years, male
25.1
GTEX-1B8SF-1826-SM-731DJ
60-69 years, male
25.1
GTEX-Y111-2626-SM-4TT24
50-59 years, male
24.8
GTEX-12WSN-2226-SM-5DUXT
40-49 years, male
24.3
GTEX-ZF29-2126-SM-DNZYX
60-69 years, female
24.0
GTEX-1LBAC-0626-SM-D3L9T
20-29 years, male
23.6
GTEX-14E1K-2626-SM-664OJ
50-59 years, male
22.8
GTEX-11P82-0926-SM-5986X
20-29 years, male
22.7
GTEX-1I6K6-0626-SM-ARU7J
30-39 years, male
22.3
GTEX-1LVAM-0626-SM-HPAFZ
50-59 years, female
22.0
GTEX-1MCQQ-2226-SM-DLHC4
60-69 years, male
22.0
GTEX-1QP9N-2026-SM-DPRZT
30-39 years, male
22.0
GTEX-ZT9W-2126-SM-51MSF
50-59 years, male
21.4
GTEX-WYVS-2026-SM-4RGNS
40-49 years, female
21.3
GTEX-11EQ9-2026-SM-5P9JI
30-39 years, male
21.2
GTEX-12WSM-1826-SM-5BC64
60-69 years, male
21.2
GTEX-1IKJJ-2826-SM-GA8ZM
60-69 years, male
21.2
GTEX-13G51-2426-SM-5LZY8
60-69 years, male
21.0
GTEX-1C64N-2926-SM-79OLM
50-59 years, male
20.9
GTEX-1H4P4-2026-SM-9WPNV
50-59 years, male
20.8
GTEX-111FC-2926-SM-5GZY7
60-69 years, male
20.6
GTEX-1IY9M-2926-SM-A96TH
60-69 years, male
20.5
GTEX-1NHNU-2226-SM-GRR2I
50-59 years, male
20.0
GTEX-1S82P-0726-SM-EVR4O
60-69 years, female
20.0
GTEX-XGQ4-2626-SM-4AT6B
50-59 years, male
20.0
GTEX-12WSL-2126-SM-5GCNG
50-59 years, male
19.9
GTEX-11WQK-2926-SM-5EQKT
50-59 years, male
19.6
GTEX-17MFQ-1626-SM-7938Z
20-29 years, male
19.5
GTEX-1IDJC-1626-SM-AHZ2R
50-59 years, male
19.3
GTEX-1MCC2-2226-SM-EV7AJ
30-39 years, female
19.3
GTEX-1RNSC-2926-SM-EV79L
60-69 years, male
19.3
GTEX-1HSEH-1826-SM-A96SA
60-69 years, male
19.1
GTEX-WOFM-2126-SM-4M9R4
20-29 years, male
19.1
GTEX-1C64O-0626-SM-7DHL1
60-69 years, male
18.8
GTEX-Z9EW-1426-SM-HPAG9
40-49 years, male
18.2
GTEX-1LC47-2426-SM-DHXKK
60-69 years, male
18.1
GTEX-1R9PM-1726-SM-E76T2
20-29 years, male
18.1
GTEX-1R9K4-0526-SM-E76P1
60-69 years, male
17.9
GTEX-13QJC-2326-SM-5Q5CD
60-69 years, female
17.5
GTEX-Y5LM-1826-SM-4VDT9
40-49 years, female
17.5
GTEX-12BJ1-2226-SM-5BC6G
60-69 years, male
17.3
GTEX-1192X-2926-SM-5N9BA
50-59 years, male
17.1
GTEX-1H1CY-2326-SM-9OSXW
60-69 years, female
17.1
GTEX-1IE54-0826-SM-AHZ2Z
40-49 years, female
17.1
GTEX-X261-2426-SM-4PQZU
50-59 years, male
17.1
GTEX-X5EB-1726-SM-4E3J7
40-49 years, male
17.0
GTEX-1B97J-2126-SM-79OL6
50-59 years, female
16.8
GTEX-178AV-1426-SM-6LLID
40-49 years, male
16.6
GTEX-1HSMQ-0926-SM-A96SI
50-59 years, male
16.6
GTEX-1KANC-1326-SM-CYPT8
50-59 years, female
16.6
GTEX-ZE7O-2926-SM-51MSG
50-59 years, female
16.6
GTEX-1LKK1-2926-SM-EVR4Z
50-59 years, female
16.5
GTEX-18QFQ-0626-SM-718AW
30-39 years, male
16.2
GTEX-1PDJ9-2126-SM-HPAFH
20-29 years, male
16.2
GTEX-13OVK-1826-SM-6PALE
40-49 years, male
16.1
GTEX-1C6VR-0726-SM-7P8OV
60-69 years, male
16.1
GTEX-1EH9U-2926-SM-7DHLX
60-69 years, male
16.0
GTEX-1HSGN-0626-SM-A9G2E
40-49 years, female
16.0
GTEX-1IDJD-2526-SM-C1YSA
30-39 years, male
16.0
GTEX-15SDE-1226-SM-HAV36
50-59 years, female
15.9
GTEX-1ICLY-0626-SM-GA915
50-59 years, male
15.9
GTEX-1314G-2026-SM-5LZUM
30-39 years, male
15.8
GTEX-18A7B-2826-SM-7KFTK
70-79 years, male
15.8
GTEX-W5X1-2426-SM-HPAGA
40-49 years, female
15.7
GTEX-ZG7Y-2426-SM-DO11H
50-59 years, male
15.6
GTEX-1OJC4-3126-SM-EXOJK
50-59 years, female
15.5
GTEX-1GMR2-2026-SM-7MKHK
50-59 years, male
15.4
GTEX-1339X-2326-SM-5HL5B
40-49 years, male
15.3
GTEX-11P81-2026-SM-5P9GT
30-39 years, female
15.2
GTEX-18D9U-2226-SM-7KFTN
40-49 years, male
15.2
GTEX-WHSB-2326-SM-4M1XK
50-59 years, male
15.0
GTEX-1IDJV-2326-SM-GA8ZL
60-69 years, male
14.9
GTEX-11ZTS-3026-SM-5EQM7
60-69 years, female
14.5
GTEX-14PJ3-1526-SM-664O9
50-59 years, male
14.3
GTEX-1445S-2926-SM-5O993
60-69 years, male
14.2
GTEX-1I4MK-1326-SM-B2LWT
50-59 years, female
14.1
GTEX-1LVAO-2626-SM-EVR4S
60-69 years, male
14.1
GTEX-WFJO-2026-SM-4LVM3
30-39 years, male
14.1
GTEX-1I1HK-2526-SM-A96SM
60-69 years, male
14.0
GTEX-YB5K-1726-SM-5IFIZ
40-49 years, female
13.9
GTEX-131XH-2626-SM-5GCNP
50-59 years, male
13.7
GTEX-1QEPI-0626-SM-E76QE
60-69 years, female
13.7
GTEX-1J8QM-1826-SM-A96TA
60-69 years, female
13.6
GTEX-1MGNQ-1926-SM-DTX8L
40-49 years, male
13.5
GTEX-14PN4-2526-SM-686ZG
50-59 years, male
13.4
GTEX-1GN1W-2526-SM-9JGHX
50-59 years, female
13.4
GTEX-1GN1V-2926-SM-9JGI3
60-69 years, male
13.3
GTEX-1J8EW-2826-SM-A96T9
60-69 years, female
12.8
GTEX-1GPI7-0326-SM-7MKH6
20-29 years, male
12.7
GTEX-WH7G-2126-SM-4M1XU
40-49 years, male
12.7
GTEX-YF7O-2226-SM-5CVN8
50-59 years, male
12.6
GTEX-1JN1M-2426-SM-ARU93
60-69 years, female
12.4
GTEX-ZA64-1726-SM-5CVMF
20-29 years, male
12.4
GTEX-1GF9X-0226-SM-7P8SM
40-49 years, female
12.3
GTEX-1PIEJ-0626-SM-DTX99
20-29 years, female
12.1
GTEX-1GTWX-2526-SM-9JGHG
60-69 years, male
11.9
GTEX-1HFI7-2426-SM-B2LXV
50-59 years, female
11.8
GTEX-1LH75-2726-SM-HL11E
50-59 years, female
11.8
GTEX-13QBU-2126-SM-5KLZN
40-49 years, female
11.6
GTEX-18A67-0626-SM-7KFSL
50-59 years, male
11.6
GTEX-1HSMP-1926-SM-GA8Z5
70-79 years, male
11.5
GTEX-11TUW-2426-SM-5EQKB
60-69 years, male
11.4
GTEX-13O21-1926-SM-5MR39
50-59 years, male
11.4
GTEX-1O97I-2826-SM-HPAEO
60-69 years, male
11.4
GTEX-1JKYR-0726-SM-AHZ3K
20-29 years, male
11.3
GTEX-1QMI2-0426-SM-EWRND
60-69 years, male
11.3
GTEX-Y5V6-2226-SM-4VDTC
60-69 years, male
11.3
GTEX-1AYD5-2726-SM-7MXVG
50-59 years, male
11.0
GTEX-1P4AB-2926-SM-EXOJR
50-59 years, male
11.0
GTEX-13113-1526-SM-5EGHV
60-69 years, female
10.9
GTEX-1CB4I-2526-SM-7MKG1
50-59 years, male
10.9
GTEX-XMK1-2626-SM-4B65R
40-49 years, male
10.6
GTEX-ZPU1-2326-SM-57WEP
40-49 years, male
10.6
GTEX-1OJC3-1026-SM-E6CQK
20-29 years, male
10.5
GTEX-15CHC-1226-SM-686ZH
60-69 years, female
10.4
GTEX-1QCLZ-2526-SM-EXUST
60-69 years, female
10.2
GTEX-WY7C-1426-SM-4OND1
50-59 years, male
9.9
GTEX-X15G-2126-SM-4PQZR
50-59 years, female
9.9
GTEX-1I6K7-0926-SM-A96SV
40-49 years, male
9.8
GTEX-XV7Q-2426-SM-4BRV8
40-49 years, female
9.7
GTEX-17KNJ-2726-SM-7KFRE
50-59 years, male
9.6
GTEX-13OVI-2326-SM-5KM47
60-69 years, female
9.4
GTEX-1JN6P-2526-SM-CNNPX
60-69 years, male
9.3
GTEX-145ME-1626-SM-5RQI3
40-49 years, female
9.2
GTEX-146FR-1226-SM-5MR78
60-69 years, female
9.2
GTEX-1HR9M-2526-SM-A9G3J
60-69 years, male
9.2
GTEX-11EMC-2526-SM-5PNVU
60-69 years, female
9.1
GTEX-1HGF4-2326-SM-GA91Q
60-69 years, male
9.1
GTEX-1PPH8-1526-SM-E6CQO
20-29 years, male
9.1
GTEX-1B932-0626-SM-731EM
40-49 years, female
8.8
GTEX-11ZTT-2226-SM-5CVLP
60-69 years, female
8.5
GTEX-1QP28-2026-SM-F2I3M
50-59 years, female
8.5
GTEX-15EU6-2626-SM-7KUN4
50-59 years, male
8.4
GTEX-1S83E-0626-SM-E9TKC
40-49 years, male
8.4
GTEX-ZXG5-2826-SM-5NQ8T
60-69 years, male
7.9
GTEX-1NSGN-0626-SM-E9J35
50-59 years, male
7.8
GTEX-1AX8Z-0626-SM-731EH
60-69 years, male
7.4
GTEX-13CF2-2426-SM-5LZYL
60-69 years, male
7.2
GTEX-1117F-3026-SM-5GZYU
60-69 years, female
7.1
GTEX-1J1R8-1826-SM-AHZ3B
40-49 years, male
7.0
GTEX-1R9K5-0626-SM-DPRZB
50-59 years, male
6.8
GTEX-ZC5H-2726-SM-5KLZW
40-49 years, female
6.8
GTEX-1AX9K-2126-SM-72D7K
50-59 years, male
6.5
GTEX-ZAB5-2326-SM-5IJFR
50-59 years, male
6.5
GTEX-13111-2326-SM-5LZUQ
50-59 years, male
5.7
GTEX-131XF-2826-SM-5EGKH
60-69 years, male
5.7
GTEX-Y3I4-1926-SM-4TT8L
50-59 years, male
5.1
GTEX-1R9PO-2626-SM-E6CPU
60-69 years, female
4.5
GTEX-14JIY-3026-SM-6EU1R
60-69 years, male
3.2
GTEX-13NYC-2626-SM-5K7VN
60-69 years, male
2.0
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SALIVARY GLAND - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
72.9
Macaque sample
Sample description
nTPM
Salivary gland nTPM: 72.9
Samples: 3
Max nTPM: 84.0
Min nTPM: 67.2
Sample C
67.2
Sample D
67.6
Sample E
84.0
SALIVARY GLAND - Pig RNA-seqi
RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
91.7
Pig sample
Sample description
nTPM
Salivary gland nTPM: 91.7
Samples: 4
Max nTPM: 172.7
Min nTPM: 42.6
Sample A
Female
42.6
Sample B
Female
91.1
Sample C
Male
172.7
Sample D
Male
60.5
SALIVARY GLAND - Mouse RNA-seqi
RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
18.3
Mouse sample
Sample description
nTPM
Salivary gland nTPM: 18.3
Samples: 4
Max nTPM: 27.0
Min nTPM: 12.6
Sample D
15.7
Sample A
12.6
Sample B
17.7
Sample C
27.0
SALIVARY GLAND - Rat RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
45.9
Rat sample
Sample description
nTPM
Salivary gland nTPM: 45.9
Samples: 4
Max nTPM: 55.1
Min nTPM: 35.8
Sample A
43.8
Sample A
35.8
Sample A
55.1
Sample A
49.0
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