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BETA
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  • LRRC4B
EVOLUTIONARY PONS Show tissue menu
BRAIN43 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES6
Select an organ to show its tissues
AMYGDALA BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CORPUS CALLOSUM DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX HIPPOCAMPAL FORMATION
HYPOTHALAMUS INSULAR CORTEX MEDULLA OBLONGATA MIDBRAIN MOTOR AND PREFRONTAL CORTEX MOTOR CORTEX OCCIPITAL CORTEX OLFACTORY BULB PERIAQUEDUCTAL GRAY PONS PREFRONTAL CORTEX PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA
SEPTUM SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:153.2 nTPM
FANTOM5:58.3 Scaled Tags Per Million
Mouse:120.7 nTPM
Rat:154.9 nTPM
Pig:79.8 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - Annotated protein expression
Pending normal tissue analysis

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

153.2
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 117.6
2301 Female, age 85, both hemispheres 132.4
2188 Female, age 91, both hemispheres 114.6
2090 Male, age 80, both hemispheres 114.0
1984 Male, age 76, both hemispheres 109.3
Dorsal cochlear nucleus
nTPM: 124.5
2802 Male, age 74, right hemisphere 138.0
2187 Female, age 91, both hemispheres 131.5
2370 Male, age 61, both hemispheres 121.4
2058 Male, age 76, both hemispheres 120.2
2378 Male, age 80, both hemispheres 111.4
Dorsal tegmental nucleus
nTPM: 125.4
2083 Male, age 80, both hemispheres 150.5
2326 Male, age 74, both hemispheres 132.0
1936 Male, age 76, left hemisphere 118.0
2358 Male, age 61, both hemispheres 101.2
Dorsolateral tegmental area
nTPM: 119.4
2654 Male, age 80, both hemispheres 145.0
2751 Female, age 85, both hemispheres 134.3
2141 Male, age 76, both hemispheres 122.2
2360 Male, age 74, both hemispheres 106.3
2337 Male, age 61, both hemispheres 89.2
Kolliker-Fuse nucleus
nTPM: 124.7
2163 Male, age 80, both hemispheres 152.5
2793 Female, age 91, left hemisphere 135.6
2315 Male, age 76, right hemisphere 86.0
Lateral lemniscal nuclei
nTPM: 132.4
2320 Female, age 91, left hemisphere 144.0
2453 Male, age 74, right hemisphere 139.7
2169 Male, age 76, both hemispheres 133.8
2746 Female, age 85, left hemisphere 126.7
2036 Male, age 80, both hemispheres 117.7
Lateral parabrachial nucleus
nTPM: 105.2
2139 Female, age 85, right hemisphere 118.3
2790 Male, age 61, both hemispheres 105.7
2013 Male, age 80, both hemispheres 105.5
2792 Male, age 76, both hemispheres 91.1
Lateral vestibular nucleus
nTPM: 153.2
2184 Male, age 76, both hemispheres 166.3
2311 Male, age 80, both hemispheres 140.1
Locus coeruleus
nTPM: 140.2
2317 Female, age 72, unknown 160.6
2162 Male, age 80, both hemispheres 158.8
1980 Male, age 76, both hemispheres 143.5
2014 Male, age 55, unknown 142.5
2720 Male, age 74, both hemispheres 138.1
2123 Female, age 91, both hemispheres 134.7
2788 Male, age 74, unknown 103.0
Medial parabrachial nucleus
nTPM: 135.0
2156 Male, age 61, both hemispheres 147.4
2463 Female, age 85, right hemisphere 143.0
2170 Female, age 91, both hemispheres 138.9
2786 Male, age 76, both hemispheres 134.5
2854 Male, age 80, both hemispheres 111.1
Medial periolivary nuclei
nTPM: 124.9
2063 Male, age 76, both hemispheres 145.1
2171 Female, age 85, both hemispheres 133.3
2458 Female, age 91, both hemispheres 126.3
2081 Male, age 80, both hemispheres 110.5
2791 Male, age 74, right hemisphere 109.5
Motor facial nucleus
nTPM: 127.3
2062 Male, age 76, both hemispheres 144.4
2795 Female, age 91, both hemispheres 144.0
2327 Male, age 80, both hemispheres 122.4
2126 Male, age 61, both hemispheres 121.6
2697 Female, age 85, both hemispheres 116.0
2365 Male, age 74, right hemisphere 115.1
Motor trigeminal nucleus
nTPM: 134.5
2335 Male, age 61, both hemispheres 150.6
2560 Male, age 74, both hemispheres 140.4
2309 Male, age 76, both hemispheres 134.7
2321 Female, age 91, both hemispheres 132.8
2079 Male, age 80, both hemispheres 113.8
Nuclei of the trapezoid body
nTPM: 132.2
2368 Female, age 91, both hemispheres 144.3
2735 Female, age 85, both hemispheres 140.4
1983 Male, age 76, both hemispheres 133.9
2159 Male, age 61, both hemispheres 121.7
2166 Male, age 80, both hemispheres 120.6
Nucleus raphe magnus
nTPM: 128.5
2459 Female, age 91, both hemispheres 142.8
2172 Female, age 85, both hemispheres 136.3
2455 Male, age 74, both hemispheres 135.0
2328 Male, age 80, both hemispheres 127.2
2051 Male, age 76, both hemispheres 126.4
2160 Male, age 61, both hemispheres 103.4
Paramedian reticular nucleus
nTPM: 122.0
2057 Male, age 80, both hemispheres 150.4
2313 Male, age 61, both hemispheres 150.0
2050 Female, age 85, both hemispheres 110.1
2052 Male, age 76, both hemispheres 77.4
Pedunculopontine tegmental nucleus
nTPM: 115.5
1921 Female, age 85, both hemispheres 132.3
2334 Male, age 80, both hemispheres 130.7
2338 Male, age 61, both hemispheres 83.7
Pontine nuclei
nTPM: 128.6
1968 Male, age 76, left hemisphere 155.4
2787 Female, age 85, both hemispheres 154.8
1863 Male, age 55, unknown 130.0
2109 Female, age 72, unknown 126.2
2319 Female, age 91, both hemispheres 125.0
2454 Male, age 74, left hemisphere 124.5
2115 Male, age 80, left hemisphere 121.8
2727 Male, age 61, right hemisphere 91.3
Pontine raphe nucleus
nTPM: 130.2
2853 Male, age 76, midline 130.8
2122 Female, age 85, midline 129.6
Posteroventral cochlear nucleus
nTPM: 111.8
2752 Female, age 85, both hemispheres 142.8
2070 Male, age 76, both hemispheres 122.0
2371 Male, age 61, both hemispheres 103.5
2135 Female, age 91, both hemispheres 102.6
2341 Male, age 80, both hemispheres 88.0
Principal sensory trigeminal nucleus
nTPM: 123.0
2324 Male, age 76, both hemispheres 154.3
2367 Female, age 91, left hemisphere 123.0
2158 Male, age 61, both hemispheres 110.3
2008 Male, age 80, left hemisphere 104.5
Reticular pontine nucleus, caudal
nTPM: 134.9
2457 Female, age 91, both hemispheres 141.2
2332 Male, age 80, right hemisphere 139.2
2559 Male, age 74, both hemispheres 135.3
2092 Male, age 76, both hemispheres 123.8
Reticular pontine nucleus, oral
nTPM: 131.4
2361 Male, age 74, both hemispheres 148.7
2167 Male, age 76, both hemispheres 138.3
2366 Female, age 91, both hemispheres 127.1
1939 Male, age 80, both hemispheres 126.0
2012 Female, age 85, both hemispheres 117.0
Reticulotegmental nucleus
nTPM: 139.5
2452 Male, age 74, both hemispheres 155.9
2322 Female, age 91, both hemispheres 146.5
2325 Male, age 76, both hemispheres 128.1
2333 Male, age 80, both hemispheres 127.7
Spinal trigeminal nucleus, oral
nTPM: 140.3
2164 Male, age 80, both hemispheres 151.8
1978 Male, age 76, both hemispheres 140.2
2737 Female, age 85, both hemispheres 128.9
Subcoeruleus area
nTPM: 137.2
2451 Male, age 74, both hemispheres 161.0
2323 Female, age 91, left hemisphere 151.1
2089 Male, age 76, left hemisphere 132.3
2369 Female, age 85, left hemisphere 129.0
1958 Male, age 80, both hemispheres 112.6
Superior olive
nTPM: 121.1
2561 Female, age 91, both hemispheres 138.8
2329 Male, age 80, right hemisphere 125.5
2020 Male, age 76, both hemispheres 124.1
2364 Male, age 74, right hemisphere 113.3
1875 Female, age 85, both hemispheres 103.6
Ventral periolivary nuclei
nTPM: 120.6
2130 Female, age 85, both hemispheres 129.7
2165 Male, age 80, both hemispheres 123.6
2794 Female, age 91, left hemisphere 116.1
2023 Male, age 76, both hemispheres 112.8
Ventrolateral tegmental area, A5 NE cell group
nTPM: 125.0
2456 Female, age 91, both hemispheres 145.2
2449 Male, age 74, both hemispheres 137.6
1959 Male, age 76, both hemispheres 122.5
2840 Female, age 85, both hemispheres 117.5
2161 Male, age 80, both hemispheres 115.4
2359 Male, age 61, both hemispheres 111.7

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

58.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 58.3
FF:10182-103D2 60 years, female 76.7
FF:10165-103B3 76 years, female 39.8
Pons
Scaled Tags Per Million: 30.9
FF:10033-101E6 18-54 years, mixed 30.9

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

79.8
Pig sample Sample description nTPM
Pons
nTPM: 79.8
Samples: 3

Max nTPM: 102.2
Min nTPM: 68.4
Sample A Female 102.2
Sample B Female 68.4
Sample C Male 68.9

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

120.7
Mouse sample Sample description nTPM
Pons
nTPM: 120.8
Samples: 4

Max nTPM: 125.4
Min nTPM: 113.0
Sample A 124.4
Sample B 125.4
Sample C 120.2
Sample D 113.0

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

154.9
Rat sample Sample description nTPM
Pons
nTPM: 154.9
Samples: 4

Max nTPM: 165.6
Min nTPM: 145.3
Sample A 165.6
Sample A 152.4
Sample A 145.3
Sample A 156.2

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