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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
Not detected
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
6.3
nTPM
HPA:
6.3
nTPM
GTEx:
4.4
nTPM
FANTOM5:
17.3
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA029957
Cholangiocytes
Not detected
Hepatocytes
Not detected
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
6.3
Female, age 60
Liver sample 21 nTPM: 5.9
Male, age 54
Liver sample 23 nTPM: 3.9
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 11.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 6.7
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 10.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 5.1
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 6.7
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 4.5
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 5.3
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 3.1
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
4.4
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 4.4
Samples: 226
Max nTPM: 18.4
Min nTPM: 0.4
Std nTPM: 2.9
Median nTPM: 3.6
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
18.4
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
15.0
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
14.0
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
13.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
13.1
GTEX-13112-1426-SM-5EGH8
50-59 years, male
12.3
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
12.0
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
11.5
GTEX-11GSP-0626-SM-5986T
60-69 years, female
11.3
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
11.2
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
10.6
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
10.5
GTEX-144GL-1426-SM-79OMA
50-59 years, male
10.0
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
9.7
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
9.7
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
9.6
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
9.4
GTEX-14E7W-1526-SM-6871X
70-79 years, male
9.2
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
8.8
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
8.8
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
8.7
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
8.6
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
8.1
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
8.1
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
8.0
GTEX-1399T-0826-SM-5IFES
60-69 years, male
7.9
GTEX-14JG1-1626-SM-664NH
40-49 years, male
7.9
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
7.8
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
7.7
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
7.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
7.4
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
7.3
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
7.2
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
7.1
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
7.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
7.1
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
7.0
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
6.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
6.9
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
6.7
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
6.7
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
6.6
GTEX-RN64-1826-SM-48FDV
50-59 years, male
6.6
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
6.5
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
6.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
6.4
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
6.4
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
6.3
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
6.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
6.2
GTEX-YECK-1926-SM-4W21H
60-69 years, male
6.1
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
6.1
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
6.1
GTEX-18A7A-1526-SM-72D69
50-59 years, female
6.0
GTEX-RU72-1426-SM-46MUF
50-59 years, female
6.0
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
6.0
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
5.9
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
5.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
5.7
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
5.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
5.6
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
5.6
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
5.5
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
5.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
5.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
5.4
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
5.4
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
5.3
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
5.3
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
5.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
5.2
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
5.1
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
5.1
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
5.1
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
5.1
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
5.1
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
5.0
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
4.9
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
4.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
4.8
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
4.7
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
4.7
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
4.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
4.6
GTEX-X261-1726-SM-4PQYT
50-59 years, male
4.6
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
4.6
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
4.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
4.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
4.5
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
4.4
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
4.4
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
4.4
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
4.3
GTEX-12696-0826-SM-5EGGE
60-69 years, male
4.2
GTEX-17HHE-0126-SM-79398
50-59 years, male
4.2
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
4.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
4.1
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
4.0
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
4.0
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
4.0
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
3.9
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
3.9
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
3.9
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
3.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
3.8
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
3.8
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
3.8
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
3.8
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
3.8
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
3.7
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
3.7
GTEX-R53T-0326-SM-48FEC
50-59 years, female
3.7
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
3.7
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
3.6
GTEX-QESD-2026-SM-447BI
20-29 years, male
3.6
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
3.6
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
3.5
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
3.5
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
3.5
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
3.5
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
3.4
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
3.4
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
3.4
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
3.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
3.3
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
3.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
3.2
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
3.2
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
3.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
3.1
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
3.1
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
3.1
GTEX-S33H-1626-SM-4AD68
30-39 years, male
3.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
3.1
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
3.0
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
3.0
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
3.0
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
3.0
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
3.0
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
2.9
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
2.9
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
2.9
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
2.9
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
2.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
2.8
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
2.8
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
2.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
2.8
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
2.8
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
2.7
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
2.7
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
2.7
GTEX-18A66-2026-SM-7189C
60-69 years, male
2.7
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
2.7
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
2.7
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
2.7
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
2.7
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
2.7
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
2.7
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
2.6
GTEX-17F96-1226-SM-79OK2
70-79 years, male
2.6
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
2.6
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
2.6
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
2.6
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
2.6
GTEX-1B932-1426-SM-793AN
40-49 years, female
2.5
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
2.5
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
2.5
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
2.5
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
2.5
GTEX-14PHX-0526-SM-664NW
50-59 years, male
2.4
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
2.4
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
2.4
GTEX-Q734-0326-SM-48U15
40-49 years, female
2.4
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
2.3
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
2.3
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
2.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
2.2
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
2.2
GTEX-QEL4-1226-SM-447A4
50-59 years, male
2.2
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
2.2
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
2.1
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
2.0
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
2.0
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
2.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
1.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
1.9
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
1.9
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
1.8
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
1.8
GTEX-P78B-1326-SM-3P611
40-49 years, female
1.8
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
1.8
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
1.8
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
1.7
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
1.7
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
1.7
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
1.7
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
1.7
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
1.6
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
1.6
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
1.6
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
1.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
1.6
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
1.6
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
1.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
1.6
GTEX-14XAO-0226-SM-68728
60-69 years, female
1.5
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
1.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
1.5
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
1.4
GTEX-S32W-1926-SM-4AD63
50-59 years, female
1.4
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
1.3
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
1.3
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
1.3
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
1.2
GTEX-14PJO-1726-SM-68719
60-69 years, male
1.2
GTEX-O5YV-0726-SM-EV798
60-69 years, female
1.1
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
1.0
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
1.0
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
1.0
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
0.9
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
0.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
0.6
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
0.6
GTEX-13113-1326-SM-5GCOI
60-69 years, female
0.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
0.4
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
The Human Protein Atlas project is funded
