The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Strong nuclear and cytoplasmic staining was displayed in glial cells in CNS, peripheral nerves and a subset of immune cells and adipocytes. Moderate cytoplasmic and membranous positivity was observed in several normal tissues including glandular cells in the gastrointestinal tract, gall bladder, prostate and epididymis and in urothelial cells. Most remaining tissues were weakly stained or negative.
Moderate to strong nuclear and cytoplasmic positivity was observed in most cells in CNS, subsets of immune cells in several tissues and in adipocytes. Strong staining was displayed in neuropil in CNS, as well as in peripheral nerves and ganglion cells. Other normal cells were weakly stained or negative.
Strong nuclear staining was observed in glial cells, subset of neuronal cells and in peripheral nerves. A subset of immune cells showed moderate to strong cytoplasmic and nuclear positivity. Most remaining normal tissues were in general negative.