GENERAL INFORMATIONi
Gene namei CTNNB1
Synonyms armadillo, beta-catenin, CTNNB
Gene descriptioni Catenin beta 1
Protein classi Cancer-related genes
Disease related genes
Human disease related genes
Plasma proteins
Predicted locationi Intracellular
Protein evidence Evidence at protein level (all genes)
GENE INFORMATIONi
Chromosome 3
Cytoband p22.1
Chromosome location (bp) 41194741 - 41260096
Number of transcriptsi 43
Ensembl ENSG00000168036 (version 103.38)
Entrez gene 1499
HGNC HGNC:2514
UniProt P35222 (UniProt - Evidence at protein level)
neXtProt NX_P35222
Antibodypedia CTNNB1 antibodies


PROTEIN STRUCTUREi

Predicted


Description: Structure prediction from Alphafold project. Structure version 2

# Chains: 1      # Clinical variants: 28      # Population variants: 240

Experimental


Description: Crystal Structure of Beta-Catenin Armadillo Repeat Region and Its C-Terminal domain (X-ray)

# Chains: 1      # Clinical variants: 0      # Population variants: 0

Antigens:

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On

Variants:

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Clinical
Population

Color scheme:

Confidence
Residue index
Chain name

Autorotate:

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On


PROTEIN BROWSERi
«
CTNNB1-201
CTNNB1-202
CTNNB1-203
CTNNB1-204
CTNNB1-205
CTNNB1-206
CTNNB1-207
CTNNB1-208
CTNNB1-209
CTNNB1-210
CTNNB1-216
CTNNB1-217
CTNNB1-218
CTNNB1-219
CTNNB1-220
CTNNB1-221
CTNNB1-222
CTNNB1-223
CTNNB1-225
CTNNB1-226
CTNNB1-228
CTNNB1-229
CTNNB1-230
CTNNB1-233
CTNNB1-234
CTNNB1-235
CTNNB1-236
CTNNB1-237
CTNNB1-238
CTNNB1-239
CTNNB1-241
CTNNB1-242
CTNNB1-244
CTNNB1-245
CTNNB1-246
CTNNB1-248
CTNNB1-249
CTNNB1-250
CTNNB1-251
CTNNB1-252
CTNNB1-254
CTNNB1-255
CTNNB1-256
»


PROTEIN INFORMATIONi
Splice variant UniProt Protein class Gene ontology Length & mass Signal peptide
(predicted)		 Transmembrane regions
(predicted)
CTNNB1-201
ENSP00000344456
ENST00000349496
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-202
ENSP00000379486
ENST00000396183
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-203
ENSP00000379488
ENST00000396185
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-204
ENSP00000385604
ENST00000405570
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-205
ENSP00000400508
ENST00000426215
C9IZ65 [Direct mapping]
Catenin beta-1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0007155 [cell adhesion]
GO:0045296 [cadherin binding]
Show all
 59 aa
6.5 kDa 		No 0
CTNNB1-206
ENSP00000412219
ENST00000431914
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-207
ENSP00000387455
ENST00000433400
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-208
ENSP00000401599
ENST00000441708
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-209
ENSP00000409302
ENST00000450969
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-210
ENSP00000411226
ENST00000453024
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-216
ENSP00000495244
ENST00000642248
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-217
ENSP00000495076
ENST00000642315
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-218
ENSP00000495719
ENST00000642426
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-219
ENSP00000496295
ENST00000642836
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-220
ENSP00000496020
ENST00000642886
A0A2R8Y750 [Direct mapping]
Catenin beta-1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 744 aa
81.4 kDa 		No 0
CTNNB1-221
ENSP00000494422
ENST00000642986
A0A2R8Y5C3 [Direct mapping]
Catenin beta-1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 737 aa
80.7 kDa 		No 0
CTNNB1-222
ENSP00000496385
ENST00000642992
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-223
ENSP00000495450
ENST00000643031
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-225
ENSP00000494677
ENST00000643297
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-226
ENSP00000494411
ENST00000643541
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-228
ENSP00000494053
ENST00000643977
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-229
ENSP00000493610
ENST00000643992
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-230
ENSP00000496649
ENST00000644138
A0A2R8Y804 [Direct mapping]
Catenin beta-1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 702 aa
77.2 kDa 		No 0
CTNNB1-233
ENSP00000494780
ENST00000644524
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-234
ENSP00000495794
ENST00000644678
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-235
ENSP00000495992
ENST00000644867
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-236
ENSP00000496511
ENST00000644873
A0A2R8Y7Z0 [Direct mapping]
Catenin beta-1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 780 aa
85.4 kDa 		No 0
CTNNB1-237
ENSP00000496584
ENST00000644906
A0A2R8Y815 [Direct mapping]
Catenin beta-1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 186 aa
20.4 kDa 		No 0
CTNNB1-238
ENSP00000496180
ENST00000645210
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-239
ENSP00000494654
ENST00000645276
A0A2R8Y5A3 [Direct mapping]
Catenin beta-1
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000122 [negative regulation of transcription by RNA polymerase II]
GO:0000578 [embryonic axis specification]
GO:0000791 [euchromatin]
GO:0000904 [cell morphogenesis involved in differentiation]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001501 [skeletal system development]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001570 [vasculogenesis]
GO:0001658 [branching involved in ureteric bud morphogenesis]
GO:0001701 [in utero embryonic development]
GO:0001702 [gastrulation with mouth forming second]
GO:0001706 [endoderm formation]
GO:0001708 [cell fate specification]
GO:0001709 [cell fate determination]
GO:0001711 [endodermal cell fate commitment]
GO:0001764 [neuron migration]
GO:0001822 [kidney development]
GO:0001840 [neural plate development]
GO:0001894 [tissue homeostasis]
GO:0001944 [vasculature development]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0002053 [positive regulation of mesenchymal cell proliferation]
GO:0002089 [lens morphogenesis in camera-type eye]
GO:0003266 [regulation of secondary heart field cardioblast proliferation]
GO:0003338 [metanephros morphogenesis]
GO:0003340 [negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005829 [cytosol]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005916 [fascia adherens]
GO:0005923 [bicellular tight junction]
GO:0006357 [regulation of transcription by RNA polymerase II]
GO:0007155 [cell adhesion]
GO:0007160 [cell-matrix adhesion]
GO:0007268 [chemical synaptic transmission]
GO:0007398 [ectoderm development]
GO:0007403 [glial cell fate determination]
GO:0007507 [heart development]
GO:0008134 [transcription factor binding]
GO:0008283 [cell population proliferation]
GO:0008284 [positive regulation of cell population proliferation]
GO:0009948 [anterior/posterior axis specification]
GO:0009950 [dorsal/ventral axis specification]
GO:0009953 [dorsal/ventral pattern formation]
GO:0009954 [proximal/distal pattern formation]
GO:0009987 [cellular process]
GO:0010468 [regulation of gene expression]
GO:0010628 [positive regulation of gene expression]
GO:0010629 [negative regulation of gene expression]
GO:0014704 [intercalated disc]
GO:0016020 [membrane]
GO:0016323 [basolateral plasma membrane]
GO:0016327 [apicolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016331 [morphogenesis of embryonic epithelium]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0016600 [flotillin complex]
GO:0019899 [enzyme binding]
GO:0019901 [protein kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0021819 [layer formation in cerebral cortex]
GO:0022009 [central nervous system vasculogenesis]
GO:0022405 [hair cycle process]
GO:0030018 [Z disc]
GO:0030027 [lamellipodium]
GO:0030054 [cell junction]
GO:0030097 [hemopoiesis]
GO:0030154 [cell differentiation]
GO:0030182 [neuron differentiation]
GO:0030217 [T cell differentiation]
GO:0030316 [osteoclast differentiation]
GO:0030324 [lung development]
GO:0030539 [male genitalia development]
GO:0030856 [regulation of epithelial cell differentiation]
GO:0030858 [positive regulation of epithelial cell differentiation]
GO:0030877 [beta-catenin destruction complex]
GO:0030900 [forebrain development]
GO:0030901 [midbrain development]
GO:0030902 [hindbrain development]
GO:0031016 [pancreas development]
GO:0031069 [hair follicle morphogenesis]
GO:0031253 [cell projection membrane]
GO:0031528 [microvillus membrane]
GO:0031641 [regulation of myelination]
GO:0032212 [positive regulation of telomere maintenance via telomerase]
GO:0032331 [negative regulation of chondrocyte differentiation]
GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter]
GO:0033077 [T cell differentiation in thymus]
GO:0034332 [adherens junction organization]
GO:0034613 [cellular protein localization]
GO:0034750 [Scrib-APC-beta-catenin complex]
GO:0035050 [embryonic heart tube development]
GO:0035112 [genitalia morphogenesis]
GO:0035115 [embryonic forelimb morphogenesis]
GO:0035116 [embryonic hindlimb morphogenesis]
GO:0035257 [nuclear hormone receptor binding]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0036520 [astrocyte-dopaminergic neuron signaling]
GO:0042127 [regulation of cell population proliferation]
GO:0042129 [regulation of T cell proliferation]
GO:0042475 [odontogenesis of dentin-containing tooth]
GO:0042733 [embryonic digit morphogenesis]
GO:0042734 [presynaptic membrane]
GO:0042981 [regulation of apoptotic process]
GO:0043123 [positive regulation of I-kappaB kinase/NF-kappaB signaling]
GO:0043296 [apical junction complex]
GO:0043410 [positive regulation of MAPK cascade]
GO:0043588 [skin development]
GO:0044093 [positive regulation of molecular function]
GO:0044338 [canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation]
GO:0045177 [apical part of cell]
GO:0045202 [synapse]
GO:0045211 [postsynaptic membrane]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045453 [bone resorption]
GO:0045595 [regulation of cell differentiation]
GO:0045596 [negative regulation of cell differentiation]
GO:0045603 [positive regulation of endothelial cell differentiation]
GO:0045667 [regulation of osteoblast differentiation]
GO:0045669 [positive regulation of osteoblast differentiation]
GO:0045670 [regulation of osteoclast differentiation]
GO:0045671 [negative regulation of osteoclast differentiation]
GO:0045743 [positive regulation of fibroblast growth factor receptor signaling pathway]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0048469 [cell maturation]
GO:0048489 [synaptic vesicle transport]
GO:0048513 [animal organ development]
GO:0048538 [thymus development]
GO:0048568 [embryonic organ development]
GO:0048599 [oocyte development]
GO:0048617 [embryonic foregut morphogenesis]
GO:0048643 [positive regulation of skeletal muscle tissue development]
GO:0048715 [negative regulation of oligodendrocyte differentiation]
GO:0050768 [negative regulation of neurogenesis]
GO:0050808 [synapse organization]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051145 [smooth muscle cell differentiation]
GO:0051884 [regulation of timing of anagen]
GO:0051973 [positive regulation of telomerase activity]
GO:0060066 [oviduct development]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060173 [limb development]
GO:0060439 [trachea morphogenesis]
GO:0060440 [trachea formation]
GO:0060441 [epithelial tube branching involved in lung morphogenesis]
GO:0060479 [lung cell differentiation]
GO:0060484 [lung-associated mesenchyme development]
GO:0060492 [lung induction]
GO:0060742 [epithelial cell differentiation involved in prostate gland development]
GO:0060769 [positive regulation of epithelial cell proliferation involved in prostate gland development]
GO:0060789 [hair follicle placode formation]
GO:0060916 [mesenchymal cell proliferation involved in lung development]
GO:0061047 [positive regulation of branching involved in lung morphogenesis]
GO:0061198 [fungiform papilla formation]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0061550 [cranial ganglion development]
GO:0070491 [repressing transcription factor binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0072033 [renal vesicle formation]
GO:0072053 [renal inner medulla development]
GO:0072054 [renal outer medulla development]
GO:0072079 [nephron tubule formation]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0097091 [synaptic vesicle clustering]
GO:0097718 [disordered domain specific binding]
GO:0098609 [cell-cell adhesion]
GO:0098685 [Schaffer collateral - CA1 synapse]
GO:0098831 [presynaptic active zone cytoplasmic component]
GO:0099092 [postsynaptic density, intracellular component]
GO:1901215 [negative regulation of neuron death]
GO:1903204 [negative regulation of oxidative stress-induced neuron death]
GO:1904501 [positive regulation of chromatin-mediated maintenance of transcription]
GO:1904793 [regulation of euchromatin binding]
GO:1904796 [regulation of core promoter binding]
GO:1904798 [positive regulation of core promoter binding]
GO:1904888 [cranial skeletal system development]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1990403 [embryonic brain development]
GO:1990791 [dorsal root ganglion development]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000017 [positive regulation of determination of dorsal identity]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
GO:2000179 [positive regulation of neural precursor cell proliferation]
GO:2001234 [negative regulation of apoptotic signaling pathway]
Show all
 783 aa
85.7 kDa 		No 0
CTNNB1-241
ENSP00000495360
ENST00000645320
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-242
ENSP00000494467
ENST00000645493
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-244
ENSP00000495286
ENST00000645900
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-245
ENSP00000495287
ENST00000645927
A0A2R8Y6G0 [Direct mapping]
Catenin beta-1
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 367 aa
40.1 kDa 		No 0
CTNNB1-246
ENSP00000494845
ENST00000645982
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Mapped to neXtProt
   neXtProt - Evidence at protein level
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000209 [protein polyubiquitination]
GO:0000791 [euchromatin]
GO:0000922 [spindle pole]
GO:0001085 [RNA polymerase II transcription factor binding]
GO:0001102 [RNA polymerase II activating transcription factor binding]
GO:0001569 [branching involved in blood vessel morphogenesis]
GO:0001837 [epithelial to mesenchymal transition]
GO:0002052 [positive regulation of neuroblast proliferation]
GO:0003682 [chromatin binding]
GO:0003713 [transcription coactivator activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005667 [transcription regulator complex]
GO:0005737 [cytoplasm]
GO:0005813 [centrosome]
GO:0005815 [microtubule organizing center]
GO:0005829 [cytosol]
GO:0005856 [cytoskeleton]
GO:0005886 [plasma membrane]
GO:0005911 [cell-cell junction]
GO:0005912 [adherens junction]
GO:0005925 [focal adhesion]
GO:0005938 [cell cortex]
GO:0007155 [cell adhesion]
GO:0007223 [Wnt signaling pathway, calcium modulating pathway]
GO:0007399 [nervous system development]
GO:0008013 [beta-catenin binding]
GO:0008022 [protein C-terminus binding]
GO:0008134 [transcription factor binding]
GO:0008285 [negative regulation of cell population proliferation]
GO:0010718 [positive regulation of epithelial to mesenchymal transition]
GO:0010909 [positive regulation of heparan sulfate proteoglycan biosynthetic process]
GO:0016020 [membrane]
GO:0016032 [viral process]
GO:0016055 [Wnt signaling pathway]
GO:0016323 [basolateral plasma membrane]
GO:0016328 [lateral plasma membrane]
GO:0016342 [catenin complex]
GO:0016525 [negative regulation of angiogenesis]
GO:0019827 [stem cell population maintenance]
GO:0019899 [enzyme binding]
GO:0019900 [kinase binding]
GO:0019903 [protein phosphatase binding]
GO:0030054 [cell junction]
GO:0030331 [estrogen receptor binding]
GO:0030877 [beta-catenin destruction complex]
GO:0030997 [regulation of centriole-centriole cohesion]
GO:0032355 [response to estradiol]
GO:0032481 [positive regulation of type I interferon production]
GO:0032991 [protein-containing complex]
GO:0032993 [protein-DNA complex]
GO:0033234 [negative regulation of protein sumoylation]
GO:0034333 [adherens junction assembly]
GO:0034394 [protein localization to cell surface]
GO:0035257 [nuclear hormone receptor binding]
GO:0035315 [hair cell differentiation]
GO:0035635 [entry of bacterium into host cell]
GO:0035995 [detection of muscle stretch]
GO:0036023 [embryonic skeletal limb joint morphogenesis]
GO:0042493 [response to drug]
GO:0042995 [cell projection]
GO:0043065 [positive regulation of apoptotic process]
GO:0043066 [negative regulation of apoptotic process]
GO:0043161 [proteasome-mediated ubiquitin-dependent protein catabolic process]
GO:0043525 [positive regulation of neuron apoptotic process]
GO:0044325 [ion channel binding]
GO:0044334 [canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition]
GO:0044336 [canonical Wnt signaling pathway involved in negative regulation of apoptotic process]
GO:0045202 [synapse]
GO:0045294 [alpha-catenin binding]
GO:0045296 [cadherin binding]
GO:0045765 [regulation of angiogenesis]
GO:0045892 [negative regulation of transcription, DNA-templated]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription by RNA polymerase II]
GO:0045976 [negative regulation of mitotic cell cycle, embryonic]
GO:0046332 [SMAD binding]
GO:0048145 [regulation of fibroblast proliferation]
GO:0048471 [perinuclear region of cytoplasm]
GO:0048660 [regulation of smooth muscle cell proliferation]
GO:0050767 [regulation of neurogenesis]
GO:0051091 [positive regulation of DNA-binding transcription factor activity]
GO:0051149 [positive regulation of muscle cell differentiation]
GO:0051571 [positive regulation of histone H3-K4 methylation]
GO:0060070 [canonical Wnt signaling pathway]
GO:0060828 [regulation of canonical Wnt signaling pathway]
GO:0061154 [endothelial tube morphogenesis]
GO:0061324 [canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation]
GO:0061549 [sympathetic ganglion development]
GO:0070062 [extracellular exosome]
GO:0070369 [beta-catenin-TCF7L2 complex]
GO:0070411 [I-SMAD binding]
GO:0070602 [regulation of centromeric sister chromatid cohesion]
GO:0071363 [cellular response to growth factor stimulus]
GO:0071681 [cellular response to indole-3-methanol]
GO:0071944 [cell periphery]
GO:0072182 [regulation of nephron tubule epithelial cell differentiation]
GO:0090279 [regulation of calcium ion import]
GO:0098609 [cell-cell adhesion]
GO:1904798 [positive regulation of core promoter binding]
GO:1904837 [beta-catenin-TCF complex assembly]
GO:1904886 [beta-catenin destruction complex disassembly]
GO:1904948 [midbrain dopaminergic neuron differentiation]
GO:1904954 [canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation]
GO:1990138 [neuron projection extension]
GO:1990907 [beta-catenin-TCF complex]
GO:1990909 [Wnt signalosome]
GO:2000008 [regulation of protein localization to cell surface]
GO:2000144 [positive regulation of DNA-templated transcription, initiation]
Show all
 781 aa
85.5 kDa 		No 0
CTNNB1-248
ENSP00000495426
ENST00000646116
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-249
ENSP00000495161
ENST00000646174
B4DGU4 [Direct mapping]
Catenin beta-1; cDNA FLJ57878, highly similar to Beta-catenin
Show all
Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Cancer-related genes
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Human disease related genes
   Cancers
   Cancers of the digestive system
   Cancers of the breast and female genital organs
   Cancers of the urinary system
   Cancers of eye, brain, and central nervous system
   Cancers of endocrine organs
   Skin diseases
   Skin and soft tissue diseases
   Other diseases
   Mental and behavioural disorders
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005515 [protein binding]
GO:0005886 [plasma membrane]
GO:0005912 [adherens junction]
GO:0007155 [cell adhesion]
GO:0030054 [cell junction]
GO:0045296 [cadherin binding]
Show all
 774 aa
84.8 kDa 		No 0
CTNNB1-250
ENSP00000494914
ENST00000646369
P35222 [Direct mapping]
Catenin beta-1
A0A024R2Q3 [Target identity:100%; Query identity:100%]
Catenin (Cadherin-associated protein), beta 1, 88kDa, isoform CRA_a
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Predicted intracellular proteins
   Intracellular proteins predicted by MDM and MDSEC
Plasma proteins
Cancer-related genes
   Candidate cancer biomarkers
   Mutated cancer genes
   Mutational cancer driver genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Other Mutations
   COSMIC Missense Mutations
   COSMIC Translocations
Disease related genes
Human disease related genes
&n