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BETA
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EVOLUTIONARY PONS Show tissue menu
BRAIN74 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:1284.5 nTPM
FANTOM5:1320.3 Scaled Tags Per Million
Macaque:590.3 nTPM
Mouse:549.4 nTPM
Rat:2852.8 nTPM
Pig:1675.2 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1284.5
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 1284.5
2301 Female, age 85, both hemispheres 1995.4
2188 Female, age 91, both hemispheres 1433.6
2090 Male, age 80, both hemispheres 1228.2
1984 Male, age 76, both hemispheres 480.8
Dorsal cochlear nucleus
nTPM: 780.1
2187 Female, age 91, both hemispheres 1023.7
2378 Male, age 80, both hemispheres 816.4
2802 Male, age 74, right hemisphere 778.7
2370 Male, age 61, both hemispheres 673.4
2058 Male, age 76, both hemispheres 608.3
Dorsal tegmental nucleus
nTPM: 746.0
2083 Male, age 80, both hemispheres 923.9
2326 Male, age 74, both hemispheres 776.8
1936 Male, age 76, left hemisphere 707.7
2358 Male, age 61, both hemispheres 575.7
Dorsolateral tegmental area
nTPM: 777.7
2751 Female, age 85, both hemispheres 1050.9
2337 Male, age 61, both hemispheres 982.2
2654 Male, age 80, both hemispheres 948.0
2360 Male, age 74, both hemispheres 505.1
2141 Male, age 76, both hemispheres 402.3
Kolliker-Fuse nucleus
nTPM: 927.6
2793 Female, age 91, left hemisphere 1456.9
2163 Male, age 80, both hemispheres 819.2
2315 Male, age 76, right hemisphere 506.5
Lateral lemniscal nuclei
nTPM: 816.5
2320 Female, age 91, left hemisphere 1222.2
2169 Male, age 76, both hemispheres 760.5
2036 Male, age 80, both hemispheres 752.0
2746 Female, age 85, left hemisphere 691.4
2453 Male, age 74, right hemisphere 656.3
Lateral parabrachial nucleus
nTPM: 937.7
2792 Male, age 76, both hemispheres 1469.9
2013 Male, age 80, both hemispheres 963.3
2790 Male, age 61, both hemispheres 718.0
2139 Female, age 85, right hemisphere 599.4
Lateral vestibular nucleus
nTPM: 951.9
2311 Male, age 80, both hemispheres 1139.7
2184 Male, age 76, both hemispheres 764.0
Locus coeruleus
nTPM: 381.0
2720 Male, age 74, both hemispheres 609.2
2162 Male, age 80, both hemispheres 557.9
2317 Female, age 72, unknown 375.6
2123 Female, age 91, both hemispheres 306.6
2788 Male, age 74, unknown 305.8
2014 Male, age 55, unknown 297.6
1980 Male, age 76, both hemispheres 214.0
Medial parabrachial nucleus
nTPM: 914.6
2170 Female, age 91, both hemispheres 1106.9
2463 Female, age 85, right hemisphere 918.9
2854 Male, age 80, both hemispheres 895.0
2786 Male, age 76, both hemispheres 862.0
2156 Male, age 61, both hemispheres 790.0
Medial periolivary nuclei
nTPM: 787.7
2458 Female, age 91, both hemispheres 1163.3
2081 Male, age 80, both hemispheres 901.8
2063 Male, age 76, both hemispheres 657.0
2791 Male, age 74, right hemisphere 612.4
2171 Female, age 85, both hemispheres 604.1
Motor facial nucleus
nTPM: 920.7
2697 Female, age 85, both hemispheres 1430.6
2126 Male, age 61, both hemispheres 1079.1
2795 Female, age 91, both hemispheres 929.5
2327 Male, age 80, both hemispheres 811.5
2365 Male, age 74, right hemisphere 734.9
2062 Male, age 76, both hemispheres 538.4
Motor trigeminal nucleus
nTPM: 994.9
2321 Female, age 91, both hemispheres 1373.2
2309 Male, age 76, both hemispheres 1046.6
2335 Male, age 61, both hemispheres 938.6
2560 Male, age 74, both hemispheres 837.0
2079 Male, age 80, both hemispheres 779.1
Nuclei of the trapezoid body
nTPM: 792.0
2166 Male, age 80, both hemispheres 1217.6
2368 Female, age 91, both hemispheres 962.0
2159 Male, age 61, both hemispheres 707.3
1983 Male, age 76, both hemispheres 622.7
2735 Female, age 85, both hemispheres 450.7
Nucleus raphe magnus
nTPM: 654.5
2328 Male, age 80, both hemispheres 967.4
2459 Female, age 91, both hemispheres 924.2
2051 Male, age 76, both hemispheres 683.4
2455 Male, age 74, both hemispheres 661.3
2172 Female, age 85, both hemispheres 373.8
2160 Male, age 61, both hemispheres 317.0
Paramedian reticular nucleus
nTPM: 819.3
2052 Male, age 76, both hemispheres 1030.0
2057 Male, age 80, both hemispheres 808.7
2313 Male, age 61, both hemispheres 724.8
2050 Female, age 85, both hemispheres 713.8
Pedunculopontine tegmental nucleus
nTPM: 740.6
2338 Male, age 61, both hemispheres 852.9
2334 Male, age 80, both hemispheres 820.5
1921 Female, age 85, both hemispheres 548.4
Pontine nuclei
nTPM: 801.1
2319 Female, age 91, both hemispheres 1265.9
2454 Male, age 74, left hemisphere 1054.3
2109 Female, age 72, unknown 925.6
1968 Male, age 76, left hemisphere 894.8
2115 Male, age 80, left hemisphere 860.6
1863 Male, age 55, unknown 669.8
2787 Female, age 85, both hemispheres 433.4
2727 Male, age 61, right hemisphere 304.2
Pontine raphe nucleus
nTPM: 522.6
2122 Female, age 85, midline 559.5
2853 Male, age 76, midline 485.7
Posteroventral cochlear nucleus
nTPM: 1138.9
2135 Female, age 91, both hemispheres 1611.5
2341 Male, age 80, both hemispheres 1338.6
2371 Male, age 61, both hemispheres 1079.0
2070 Male, age 76, both hemispheres 1038.3
2752 Female, age 85, both hemispheres 627.1
Principal sensory trigeminal nucleus
nTPM: 799.8
2367 Female, age 91, left hemisphere 1202.3
2324 Male, age 76, both hemispheres 834.2
2008 Male, age 80, left hemisphere 602.2
2158 Male, age 61, both hemispheres 560.3
Reticular pontine nucleus, caudal
nTPM: 922.2
2457 Female, age 91, both hemispheres 1045.1
2559 Male, age 74, both hemispheres 990.5
2092 Male, age 76, both hemispheres 933.9
2332 Male, age 80, right hemisphere 719.2
Reticular pontine nucleus, oral
nTPM: 924.9
2366 Female, age 91, both hemispheres 1415.7
2167 Male, age 76, both hemispheres 915.7
1939 Male, age 80, both hemispheres 830.8
2012 Female, age 85, both hemispheres 789.9
2361 Male, age 74, both hemispheres 672.4
Reticulotegmental nucleus
nTPM: 775.6
2322 Female, age 91, both hemispheres 880.2
2452 Male, age 74, both hemispheres 822.8
2333 Male, age 80, both hemispheres 818.6
2325 Male, age 76, both hemispheres 580.8
Spinal trigeminal nucleus, oral
nTPM: 715.4
2164 Male, age 80, both hemispheres 913.7
1978 Male, age 76, both hemispheres 720.1
2737 Female, age 85, both hemispheres 512.6
Subcoeruleus area
nTPM: 819.3
2369 Female, age 85, left hemisphere 1234.5
2089 Male, age 76, left hemisphere 808.3
1958 Male, age 80, both hemispheres 763.4
2451 Male, age 74, both hemispheres 739.1
2323 Female, age 91, left hemisphere 551.0
Superior olive
nTPM: 959.3
2020 Male, age 76, both hemispheres 1197.0
2561 Female, age 91, both hemispheres 1176.2
2329 Male, age 80, right hemisphere 1080.1
1875 Female, age 85, both hemispheres 677.7
2364 Male, age 74, right hemisphere 665.5
Ventral periolivary nuclei
nTPM: 946.7
2023 Male, age 76, both hemispheres 1304.2
2794 Female, age 91, left hemisphere 955.5
2165 Male, age 80, both hemispheres 837.9
2130 Female, age 85, both hemispheres 689.1
Ventrolateral tegmental area, A5 NE cell group
nTPM: 874.3
2456 Female, age 91, both hemispheres 1095.9
2359 Male, age 61, both hemispheres 1078.5
1959 Male, age 76, both hemispheres 843.1
2161 Male, age 80, both hemispheres 819.6
2840 Female, age 85, both hemispheres 784.7
2449 Male, age 74, both hemispheres 624.0

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1320.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 1019.6
FF:10182-103D2 60 years, female 1152.4
FF:10165-103B3 76 years, female 886.7
Pons
Scaled Tags Per Million: 1320.3
FF:10033-101E6 18-54 years, mixed 1320.3

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

590.3
Macaque sample Sample description nTPM
Pons
nTPM: 590.3
Samples: 2

Max nTPM: 663.0
Min nTPM: 517.6
Sample A 663.0
Sample B 517.6

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1675.2
Pig sample Sample description nTPM
Pons
nTPM: 1675.2
Samples: 3

Max nTPM: 2175.1
Min nTPM: 1357.0
Sample A Female 1357.0
Sample B Female 1493.5
Sample C Male 2175.1

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

549.4
Mouse sample Sample description nTPM
Pons
nTPM: 549.4
Samples: 4

Max nTPM: 689.3
Min nTPM: 455.9
Sample A 689.3
Sample B 472.0
Sample C 580.5
Sample D 455.9

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2852.8
Rat sample Sample description nTPM
Pons
nTPM: 2852.8
Samples: 4

Max nTPM: 3079.1
Min nTPM: 2683.7
Sample A 3079.1
Sample A 2683.7
Sample A 2762.9
Sample A 2885.5

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