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BETA
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  • AQP4
EVOLUTIONARY PONS Show tissue menu
BRAIN74 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

66.214
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:445.7 nTPM
FANTOM5:641.4 Scaled Tags Per Million
Macaque:619.9 nTPM
Mouse:108.4 nTPM
Rat:347.3 nTPM
Pig:700.4 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity.

, antibody CAB005079
Pons mean intensity 66.214
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 25.077
Parabrachial nucleus 66.214
Principle sensory trigeminal nucleus 37.887
Locus coeruleus 39.258
Pontine nucleus 34.922
Vestibular nucleus 28.961
Pontine reticular nucleus, oral 19.950
Lateral lemniscus 15.124
Superior paraolivary nucleus 16.565

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

445.7
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 302.4
2301 Female, age 85, both hemispheres 371.3
2090 Male, age 80, both hemispheres 332.3
1984 Male, age 76, both hemispheres 310.8
2188 Female, age 91, both hemispheres 195.3
Dorsal cochlear nucleus
nTPM: 392.7
2370 Male, age 61, both hemispheres 588.1
2058 Male, age 76, both hemispheres 394.7
2378 Male, age 80, both hemispheres 358.5
2802 Male, age 74, right hemisphere 329.0
2187 Female, age 91, both hemispheres 293.3
Dorsal tegmental nucleus
nTPM: 400.3
1936 Male, age 76, left hemisphere 473.0
2083 Male, age 80, both hemispheres 441.1
2326 Male, age 74, both hemispheres 400.7
2358 Male, age 61, both hemispheres 286.4
Dorsolateral tegmental area
nTPM: 445.7
2360 Male, age 74, both hemispheres 772.9
2751 Female, age 85, both hemispheres 444.4
2654 Male, age 80, both hemispheres 427.5
2141 Male, age 76, both hemispheres 352.5
2337 Male, age 61, both hemispheres 231.0
Kolliker-Fuse nucleus
nTPM: 416.1
2315 Male, age 76, right hemisphere 800.6
2163 Male, age 80, both hemispheres 309.7
2793 Female, age 91, left hemisphere 137.9
Lateral lemniscal nuclei
nTPM: 217.1
2746 Female, age 85, left hemisphere 300.3
2169 Male, age 76, both hemispheres 266.8
2036 Male, age 80, both hemispheres 237.8
2453 Male, age 74, right hemisphere 152.5
2320 Female, age 91, left hemisphere 128.3
Lateral parabrachial nucleus
nTPM: 401.8
2139 Female, age 85, right hemisphere 576.5
2792 Male, age 76, both hemispheres 483.5
2013 Male, age 80, both hemispheres 369.7
2790 Male, age 61, both hemispheres 177.5
Lateral vestibular nucleus
nTPM: 374.8
2311 Male, age 80, both hemispheres 384.5
2184 Male, age 76, both hemispheres 365.1
Locus coeruleus
nTPM: 384.7
2317 Female, age 72, unknown 552.0
2788 Male, age 74, unknown 482.3
2014 Male, age 55, unknown 407.6
2123 Female, age 91, both hemispheres 394.7
1980 Male, age 76, both hemispheres 381.3
2162 Male, age 80, both hemispheres 288.1
2720 Male, age 74, both hemispheres 187.0
Medial parabrachial nucleus
nTPM: 322.6
2463 Female, age 85, right hemisphere 391.6
2786 Male, age 76, both hemispheres 349.1
2156 Male, age 61, both hemispheres 329.5
2170 Female, age 91, both hemispheres 306.5
2854 Male, age 80, both hemispheres 236.5
Medial periolivary nuclei
nTPM: 311.9
2791 Male, age 74, right hemisphere 637.7
2063 Male, age 76, both hemispheres 320.1
2171 Female, age 85, both hemispheres 275.0
2081 Male, age 80, both hemispheres 181.5
2458 Female, age 91, both hemispheres 145.4
Motor facial nucleus
nTPM: 256.6
2365 Male, age 74, right hemisphere 396.2
2062 Male, age 76, both hemispheres 357.0
2126 Male, age 61, both hemispheres 272.1
2795 Female, age 91, both hemispheres 255.2
2697 Female, age 85, both hemispheres 157.3
2327 Male, age 80, both hemispheres 101.7
Motor trigeminal nucleus
nTPM: 237.8
2309 Male, age 76, both hemispheres 377.8
2335 Male, age 61, both hemispheres 353.7
2079 Male, age 80, both hemispheres 178.4
2321 Female, age 91, both hemispheres 154.5
2560 Male, age 74, both hemispheres 124.8
Nuclei of the trapezoid body
nTPM: 244.3
1983 Male, age 76, both hemispheres 331.8
2735 Female, age 85, both hemispheres 284.3
2368 Female, age 91, both hemispheres 234.7
2159 Male, age 61, both hemispheres 201.1
2166 Male, age 80, both hemispheres 169.4
Nucleus raphe magnus
nTPM: 230.4
2455 Male, age 74, both hemispheres 439.9
2051 Male, age 76, both hemispheres 302.9
2160 Male, age 61, both hemispheres 211.6
2328 Male, age 80, both hemispheres 177.0
2172 Female, age 85, both hemispheres 128.1
2459 Female, age 91, both hemispheres 122.7
Paramedian reticular nucleus
nTPM: 349.1
2057 Male, age 80, both hemispheres 417.0
2052 Male, age 76, both hemispheres 378.3
2313 Male, age 61, both hemispheres 347.8
2050 Female, age 85, both hemispheres 253.5
Pedunculopontine tegmental nucleus
nTPM: 384.6
1921 Female, age 85, both hemispheres 443.0
2334 Male, age 80, both hemispheres 410.5
2338 Male, age 61, both hemispheres 300.2
Pontine nuclei
nTPM: 192.6
1863 Male, age 55, unknown 306.7
1968 Male, age 76, left hemisphere 251.9
2115 Male, age 80, left hemisphere 197.5
2787 Female, age 85, both hemispheres 195.8
2109 Female, age 72, unknown 188.3
2319 Female, age 91, both hemispheres 163.3
2727 Male, age 61, right hemisphere 162.4
2454 Male, age 74, left hemisphere 74.8
Pontine raphe nucleus
nTPM: 299.0
2853 Male, age 76, midline 342.8
2122 Female, age 85, midline 255.3
Posteroventral cochlear nucleus
nTPM: 335.6
2371 Male, age 61, both hemispheres 560.6
2752 Female, age 85, both hemispheres 359.1
2070 Male, age 76, both hemispheres 296.9
2341 Male, age 80, both hemispheres 281.7
2135 Female, age 91, both hemispheres 179.7
Principal sensory trigeminal nucleus
nTPM: 232.1
2324 Male, age 76, both hemispheres 416.1
2158 Male, age 61, both hemispheres 206.1
2008 Male, age 80, left hemisphere 186.9
2367 Female, age 91, left hemisphere 119.4
Reticular pontine nucleus, caudal
nTPM: 180.3
2092 Male, age 76, both hemispheres 377.2
2457 Female, age 91, both hemispheres 123.9
2559 Male, age 74, both hemispheres 110.5
2332 Male, age 80, right hemisphere 109.6
Reticular pontine nucleus, oral
nTPM: 272.3
1939 Male, age 80, both hemispheres 468.3
2167 Male, age 76, both hemispheres 353.0
2012 Female, age 85, both hemispheres 341.1
2366 Female, age 91, both hemispheres 128.3
2361 Male, age 74, both hemispheres 70.8
Reticulotegmental nucleus
nTPM: 263.5
2325 Male, age 76, both hemispheres 333.2
2333 Male, age 80, both hemispheres 299.2
2322 Female, age 91, both hemispheres 246.3
2452 Male, age 74, both hemispheres 175.5
Spinal trigeminal nucleus, oral
nTPM: 278.5
2737 Female, age 85, both hemispheres 341.0
1978 Male, age 76, both hemispheres 305.5
2164 Male, age 80, both hemispheres 189.1
Subcoeruleus area
nTPM: 317.9
2369 Female, age 85, left hemisphere 442.7
1958 Male, age 80, both hemispheres 348.1
2323 Female, age 91, left hemisphere 298.8
2451 Male, age 74, both hemispheres 261.2
2089 Male, age 76, left hemisphere 238.4
Superior olive
nTPM: 282.2
2364 Male, age 74, right hemisphere 646.2
2020 Male, age 76, both hemispheres 275.1
1875 Female, age 85, both hemispheres 202.1
2561 Female, age 91, both hemispheres 147.5
2329 Male, age 80, right hemisphere 140.1
Ventral periolivary nuclei
nTPM: 250.9
2130 Female, age 85, both hemispheres 319.9
2023 Male, age 76, both hemispheres 291.2
2165 Male, age 80, both hemispheres 237.8
2794 Female, age 91, left hemisphere 154.5
Ventrolateral tegmental area, A5 NE cell group
nTPM: 270.1
2359 Male, age 61, both hemispheres 390.6
2840 Female, age 85, both hemispheres 297.0
1959 Male, age 76, both hemispheres 290.1
2449 Male, age 74, both hemispheres 241.4
2456 Female, age 91, both hemispheres 201.4
2161 Male, age 80, both hemispheres 200.1

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

641.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 641.4
FF:10165-103B3 76 years, female 731.7
FF:10182-103D2 60 years, female 551.2
Pons
Scaled Tags Per Million: 470.9
FF:10033-101E6 18-54 years, mixed 470.9

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

619.9
Macaque sample Sample description nTPM
Pons
nTPM: 619.9
Samples: 2

Max nTPM: 705.4
Min nTPM: 534.4
Sample A 534.4
Sample B 705.4

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

700.4
Pig sample Sample description nTPM
Pons
nTPM: 700.4
Samples: 3

Max nTPM: 784.9
Min nTPM: 655.9
Sample A Female 660.4
Sample B Female 655.9
Sample C Male 784.9

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

108.4
Mouse sample Sample description nTPM
Pons
nTPM: 108.4
Samples: 4

Max nTPM: 117.7
Min nTPM: 99.9
Sample A 103.5
Sample B 99.9
Sample C 112.5
Sample D 117.7

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

347.3
Rat sample Sample description nTPM
Pons
nTPM: 347.3
Samples: 4

Max nTPM: 373.7
Min nTPM: 329.7
Sample A 329.7
Sample A 373.7
Sample A 338.6
Sample A 347.3

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