DEFB109B
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BETA
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  • EVOLUTION

  • DEFB109B
EVOLUTIONARY MIDBRAIN Show tissue menu
BRAIN20 EYE4 ENDOCRINE TISSUES4 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM10 BREAST & FEMALE REPRODUCTIVE SYSTEM8 MUSCLE & VASCULAR TISSUE11 CONNECTIVE & SOFT TISSUE6 SKIN4 BONE MARROW & LYMPHOID TISSUES6
Select an organ to show its tissues
AMYGDALA CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS ENTORHINAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA MIDBRAIN
MOTOR AND PREFRONTAL CORTEX OLFACTORY BULB PONS RETROSPLENIAL AND CINGULATE CORTEX SEPTUM SOMATOSENSORY CORTEX SPINAL CORD THALAMUS VENTRAL FOREBRAIN VISUAL CORTEX
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS
BREAST CERVIX ENDOMETRIUM FALLOPIAN TUBE OVARY PLACENTA UTERUS VAGINA
AORTA DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ADIPOSE TISSUE BROWN ADIPOSE TISSUE EAR CANAL EAR CARTILAGE SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:36.2 nTPM
Mouse:0.0 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

36.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 32.7
1833 Male, age 53, unknown 39.4
1830 Male, age 51, unknown 39.0
2411 Female, age 72, unknown 36.6
2219 Male, age 76, both hemispheres 36.0
1827 Male, age 72, unknown 32.6
2828 Female, age 72, unknown 30.7
2019 Male, age 18, unknown 29.4
1870 Female, age 42, unknown 29.2
2586 Male, age 75, left hemisphere 27.4
2666 Male, age 74, left hemisphere 27.1
Dorsal raphe nucleus
nTPM: 31.1
2016 Female, age 72, unknown 36.4
2047 Male, age 72, unknown 34.9
2750 Male, age 76, both hemispheres 34.8
1828 Male, age 53, unknown 27.9
2298 Female, age 72, unknown 21.5
Inferior colliculus
nTPM: 35.2
2849 Male, age 72, unknown 37.9
1848 Female, age 42, unknown 37.4
1890 Male, age 53, unknown 34.3
2097 Female, age 72, unknown 31.2
Median raphe nucleus
nTPM: 24.9
2220 Male, age 76, midline 24.9
Periaquaductal grey, anterior
nTPM: 25.7
1947 Male, age 18, unknown 33.7
1795 Male, age 51, unknown 22.3
2502 Female, age 75, unknown 21.1
Periaquaductal grey, dorsal
nTPM: 36.2
2464 Female, age 72, unknown 40.6
1831 Male, age 72, unknown 37.4
1840 Male, age 53, unknown 35.3
2850 Male, age 76, both hemispheres 31.5
Periaquaductal grey, lateral
nTPM: 28.7
2053 Male, age 18, unknown 30.4
2272 Male, age 74, both hemispheres 28.1
2140 Male, age 76, both hemispheres 27.6
Pretectal area
nTPM: 29.2
2407 Male, age 75, both hemispheres 37.1
2825 Male, age 18, unknown 33.3
2667 Female, age 75, unknown 32.8
2316 Male, age 76, right hemisphere 31.5
2273 Male, age 74, both hemispheres 31.2
2224 Female, age 72, unknown 31.0
1944 Female, age 72, unknown 29.6
1815 Male, age 53, unknown 26.8
2007 Male, age 72, unknown 23.4
1816 Male, age 51, unknown 22.6
1817 Female, age 42, unknown 22.2
Red nucleus
nTPM: 35.4
2823 Male, age 76, right hemisphere 49.3
1904 Male, age 53, unknown 43.5
1954 Female, age 42, unknown 42.3
2503 Female, age 72, unknown 39.8
2588 Male, age 74, left hemisphere 38.2
1865 Male, age 51, unknown 37.2
1821 Female, age 72, unknown 31.8
2725 Female, age 75, unknown 31.5
2584 Male, age 75, left hemisphere 30.1
2785 Male, age 18, unknown 28.4
2227 Male, age 72, unknown 26.7
2769 Male, age 72, unknown 26.6
Substantia nigra
nTPM: 32.4
2241 Male, age 72, unknown 56.1
2590 Female, age 75, unknown 38.1
2409 Female, age 72, unknown 34.4
2583 Male, age 75, right hemisphere 33.5
1941 Male, age 53, unknown 30.6
2699 Male, age 18, unknown 29.8
2665 Male, age 74, both hemispheres 28.7
1851 Male, age 51, unknown 25.3
1889 Female, age 72, unknown 25.1
1916 Female, age 42, unknown 21.9
Superior colliculus
nTPM: 30.2
1895 Male, age 76, right hemisphere 50.2
1839 Male, age 51, unknown 33.7
2587 Male, age 74, left hemisphere 30.4
2664 Male, age 75, both hemispheres 29.2
2087 Female, age 72, unknown 28.2
2668 Female, age 75, unknown 28.0
1913 Female, age 42, unknown 26.9
1995 Male, age 72, unknown 26.8
2261 Male, age 18, unknown 25.7
1796 Male, age 53, unknown 23.4
Ventral tegmental area
nTPM: 29.8
1942 Male, age 51, unknown 35.9
2021 Male, age 53, unknown 31.1
2410 Female, age 72, unknown 29.7
2223 Female, age 72, unknown 29.6
1915 Female, age 42, unknown 26.4
2218 Male, age 76, both hemispheres 25.9

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.0
Mouse sample Sample description nTPM
Midbrain
nTPM: 0.0
Samples: 4

Max nTPM: 0.0
Min nTPM: 0.0
Sample A 0.0
Sample B 0.0
Sample C 0.0
Sample D 0.0

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