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BETA
  • SUMMARY

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  • BRAIN

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  • EVOLUTION

  • CD300H
EVOLUTIONARY MIDBRAIN Show tissue menu
BRAIN65 EYE3 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER2 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM8 BREAST & FEMALE REPRODUCTIVE SYSTEM9 MUSCLE & VASCULAR TISSUE10 CONNECTIVE & SOFT TISSUE14 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS CAUDATE NUCLEUS CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FUSIFORM GYRUS
GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL CORTEX SEPTUM
SOMATOSENSORY CORTEX SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD WHITE MATTER
CORNEA LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS PENIS PROSTATE SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE OVARY PLACENTA UTERUS VAGINA
AORTA HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:0.2 nTPM
FANTOM5:0.0 Scaled Tags Per Million
Macaque:0.6 nTPM
Pig:2.0 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 0.0
1870 Female, age 42, unknown 0.2
1830 Male, age 51, unknown 0.1
2828 Female, age 72, unknown 0.1
1827 Male, age 72, unknown 0.0
1833 Male, age 53, unknown 0.0
2019 Male, age 18, unknown 0.0
2219 Male, age 76, both hemispheres 0.0
2411 Female, age 72, unknown 0.0
2586 Male, age 75, left hemisphere 0.0
2666 Male, age 74, left hemisphere 0.0
Dorsal raphe nucleus
nTPM: 0.0
1828 Male, age 53, unknown 0.1
2016 Female, age 72, unknown 0.0
2047 Male, age 72, unknown 0.0
2298 Female, age 72, unknown 0.0
2750 Male, age 76, both hemispheres 0.0
Inferior colliculus
nTPM: 0.0
1848 Female, age 42, unknown 0.1
1890 Male, age 53, unknown 0.0
2097 Female, age 72, unknown 0.0
2849 Male, age 72, unknown 0.0
Median raphe nucleus
nTPM: 0.0
2220 Male, age 76, midline 0.0
Periaquaductal grey, anterior
nTPM: 0.2
2502 Female, age 75, unknown 0.3
1947 Male, age 18, unknown 0.2
1795 Male, age 51, unknown 0.1
Periaquaductal grey, dorsal
nTPM: 0.1
1831 Male, age 72, unknown 0.2
1840 Male, age 53, unknown 0.1
2464 Female, age 72, unknown 0.1
2850 Male, age 76, both hemispheres 0.0
Periaquaductal grey, lateral
nTPM: 0.0
2140 Male, age 76, both hemispheres 0.1
2053 Male, age 18, unknown 0.0
2272 Male, age 74, both hemispheres 0.0
Pretectal area
nTPM: 0.2
2407 Male, age 75, both hemispheres 0.8
1944 Female, age 72, unknown 0.3
2316 Male, age 76, right hemisphere 0.3
2667 Female, age 75, unknown 0.2
1816 Male, age 51, unknown 0.1
1817 Female, age 42, unknown 0.1
1815 Male, age 53, unknown 0.0
2007 Male, age 72, unknown 0.0
2224 Female, age 72, unknown 0.0
2273 Male, age 74, both hemispheres 0.0
2825 Male, age 18, unknown 0.0
Red nucleus
nTPM: 0.1
1821 Female, age 72, unknown 0.2
2227 Male, age 72, unknown 0.2
1865 Male, age 51, unknown 0.1
1954 Female, age 42, unknown 0.1
2503 Female, age 72, unknown 0.1
2725 Female, age 75, unknown 0.1
1904 Male, age 53, unknown 0.0
2584 Male, age 75, left hemisphere 0.0
2588 Male, age 74, left hemisphere 0.0
2769 Male, age 72, unknown 0.0
2785 Male, age 18, unknown 0.0
2823 Male, age 76, right hemisphere 0.0
Substantia nigra
nTPM: 0.1
2665 Male, age 74, both hemispheres 0.4
1851 Male, age 51, unknown 0.1
1916 Female, age 42, unknown 0.1
1889 Female, age 72, unknown 0.0
1941 Male, age 53, unknown 0.0
2241 Male, age 72, unknown 0.0
2409 Female, age 72, unknown 0.0
2583 Male, age 75, right hemisphere 0.0
2590 Female, age 75, unknown 0.0
2699 Male, age 18, unknown 0.0
Superior colliculus
nTPM: 0.1
1796 Male, age 53, unknown 0.3
2664 Male, age 75, both hemispheres 0.3
1995 Male, age 72, unknown 0.2
1839 Male, age 51, unknown 0.1
1913 Female, age 42, unknown 0.1
2087 Female, age 72, unknown 0.1
1895 Male, age 76, right hemisphere 0.0
2261 Male, age 18, unknown 0.0
2587 Male, age 74, left hemisphere 0.0
2668 Female, age 75, unknown 0.0
Ventral tegmental area
nTPM: 0.0
1915 Female, age 42, unknown 0.1
1942 Male, age 51, unknown 0.1
2223 Female, age 72, unknown 0.1
2021 Male, age 53, unknown 0.0
2218 Male, age 76, both hemispheres 0.0
2410 Female, age 72, unknown 0.0

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

0
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 0.0
FF:10158-103A5 76 years, female 0.0

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

0.6
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 0.6
Samples: 1

Max nTPM: 0.6
Min nTPM: 0.6
Sample A 0.6
Midbrain
nTPM: 0.5
Samples: 1

Max nTPM: 0.5
Min nTPM: 0.5
Sample A 0.5
Superior colliculi
nTPM: 0.5
Samples: 1

Max nTPM: 0.5
Min nTPM: 0.5
Sample A 0.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 1.4
Samples: 3

Max nTPM: 2.0
Min nTPM: 0.7
Sample A Female 0.7
Sample B Female 2.0
Sample C Male 1.5
Midbrain
nTPM: 1.9
Samples: 3

Max nTPM: 2.3
Min nTPM: 1.5
Sample B Female 2.3
Sample C Male 1.5
Sample D Male 1.8
Periaqueductal gray
nTPM: 2.0
Samples: 3

Max nTPM: 2.2
Min nTPM: 1.8
Sample B Female 1.8
Sample C Male 1.9
Sample D Male 2.2
Superior colliculi
nTPM: 1.3
Samples: 4

Max nTPM: 1.7
Min nTPM: 0.9
Sample A Female 0.9
Sample B Female 1.7
Sample C Male 1.3
Sample D Male 1.3

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