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BETA
  • SUMMARY

  • TISSUE

  • BRAIN

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  • H2AC19
EVOLUTIONARY CEREBRAL CORTEX Show tissue menu
BRAIN73 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE11 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX FUSIFORM GYRUS
GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX MOTOR CORTEX
OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM SOMATOSENSORY CORTEX
SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
Protein evolution
Brain
Evolutionary methods
CEREBRAL CORTEX - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:6.6 nTPM
HPA:6.6 nTPM
HPA Brain:157.4 nTPM
HPA PFC Brain:23.6 nTPM
FANTOM5:7.5 Scaled Tags Per Million
Macaque:13.6 nTPM
Mouse:41.2 nTPM
Rat:39.3 nTPM
Pig:88.0 nTPM

CEREBRAL CORTEX - Annotated protein expression
Pending normal tissue analysis

CEREBRAL CORTEX - PROTEINTALKS DB MS
Median intensity 149863
Sample Intensity
Cerebral cortex_01
182870
Cerebral cortex_02
172284
Cerebral cortex_03
146075
Cerebral cortex_04
204662
Cerebral cortex_05
305026
Cerebral cortex_06
322700
Cerebral cortex_07
193693
Cerebral cortex_08
187998
Cerebral cortex_09
839842
Cerebral cortex_10
126926
Cerebral cortex_11
222922
Cerebral cortex_12
87174
Cerebral cortex_13
120505
Cerebral cortex_14
333945
Cerebral cortex_15
197407
Cerebral cortex_16
371437
Cerebral cortex_17
152349
Cerebral cortex_18
124243
Cerebral cortex_19
109776
Cerebral cortex_20
177888
Cerebral cortex_21
331178
Cerebral cortex_22
211828
Cerebral cortex_23
305370
Cerebral cortex_24
80477
Cerebral cortex_25
80573
Cerebral cortex_26
92506
Cerebral cortex_27
96325
Cerebral cortex_28
139159
Cerebral cortex_29
202053
Cerebral cortex_30
103940
Cerebral cortex_31
72986
Cerebral cortex_32
92024
Cerebral cortex_33
283625
Cerebral cortex_34
58281
Cerebral cortex_35
147376
Cerebral cortex_36
73508
Cerebral cortex_37
84082
Cerebral cortex_38
107494

CEREBRAL CORTEX - MANN MS
Median intensity ND
Replicate Intensity

CEREBRAL CORTEX - HPA RNA-seqi

The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.

Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.

Average nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

6.6
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 9.6
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 3.4
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

overview
Male, age 70
Cerebral cortex sample 106
nTPM: 6.9
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65


CEREBRAL CORTEX - HPA Brain Stereo-seq

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

157.4
Sample id Sample description nTPM
Angular gyrus
nTPM: 94.8
2265 Female, age 91, left hemisphere 131.1
1790 Male, age 76, right hemisphere 111.1
2103 Male, age 75, left hemisphere 97.9
2722 Male, age 61, left hemisphere 96.2
1866 Male, age 76, both hemispheres 87.8
2602 Female, age 94, right hemisphere 86.6
2260 Female, age 72, left hemisphere 77.4
2221 Female, age 67, right hemisphere 70.0
Angular gyrus (white matter)
nTPM: 128.8
1920 Male, age 76, both hemispheres 128.8
Anterior cingulate cortex, supragenual-dorsal
nTPM: 101.3
2478 Female, age 67, right hemisphere 128.5
2547 Male, age 74, left hemisphere 102.3
2472 Male, age 75, left hemisphere 98.3
2342 Female, age 94, right hemisphere 90.7
1896 Female, age 85, right hemisphere 86.9
Anterior cingulate cortex, supragenual-ventral
nTPM: 89.0
2538 Male, age 75, left hemisphere 98.3
1755 Female, age 94, right hemisphere 96.5
2479 Female, age 67, right hemisphere 88.5
1950 Female, age 85, right hemisphere 87.6
1761 Male, age 74, left hemisphere 74.0
Anterior insular cortex, dorsal
nTPM: 122.8
2235 Female, age 91, right hemisphere 240.3
2001 Male, age 76, right hemisphere 92.4
2670 Male, age 75, left hemisphere 80.3
2506 Female, age 94, right hemisphere 78.1
Anterior insular cortex, ventral
nTPM: 85.0
2507 Female, age 94, left hemisphere 96.8
1852 Male, age 76, left hemisphere 91.5
2596 Male, age 75, left hemisphere 90.9
2262 Female, age 67, right hemisphere 81.2
1925 Female, age 91, left hemisphere 78.0
2757 Male, age 61, right hemisphere 71.6
Area parastriata, inferior
nTPM: 100.8
2234 Male, age 75, left hemisphere 131.8
2509 Female, age 94, left hemisphere 125.8
1789 Male, age 76, right hemisphere 101.1
2421 Female, age 91, left hemisphere 94.8
2268 Male, age 61, right hemisphere 85.6
1760 Female, age 67, left hemisphere 84.0
1758 Female, age 72, right hemisphere 82.8
Area parastriata, parietal
nTPM: 105.3
2420 Male, age 75, left hemisphere 121.6
2233 Male, age 61, right hemisphere 115.6
2236 Female, age 91, left hemisphere 109.2
2680 Female, age 94, right hemisphere 93.4
1785 Male, age 76, right hemisphere 86.6
Area parastriata, superior
nTPM: 116.3
2435 Male, age 61, left hemisphere 188.7
2604 Female, age 94, right hemisphere 120.6
2684 Female, age 67, left hemisphere 107.2
1773 Female, age 91, left hemisphere 106.7
2419 Male, age 75, right hemisphere 90.6
2881 Male, age 76, left hemisphere 83.9
Area parastriata, temporal
nTPM: 94.1
1804 Male, age 76, right hemisphere 109.2
2267 Male, age 61, right hemisphere 100.8
2681 Female, age 94, right hemisphere 87.5
2424 Female, age 67, left hemisphere 87.1
2471 Male, age 75, left hemisphere 85.7
Area striata
nTPM: 123.7
2002 Female, age 91, right hemisphere 251.2
1884 Male, age 76, left hemisphere 144.5
2427 Female, age 91, left hemisphere 101.5
2679 Female, age 94, right hemisphere 96.7
1753 Female, age 72, right hemisphere 85.8
2417 Male, age 61, right hemisphere 62.2
Area striata (white matter)
nTPM: 123.3
2258 Female, age 91, left hemisphere 123.3
Claustrum
nTPM: 97.1
2292 Female, age 85, both hemispheres 120.7
2568 Male, age 61, both hemispheres 107.7
2392 Female, age 94, both hemispheres 102.2
1956 Male, age 74, unknown 99.7
2196 Female, age 79, unknown 99.1
2198 Male, age 80, both hemispheres 99.1
2491 Male, age 75, both hemispheres 91.4
2284 Female, age 91, both hemispheres 84.9
2645 Female, age 72, unknown 69.1
Corpus callosum, genu (white matter)
nTPM: 145.4
1934 Male, age 61, right hemisphere 166.4
1887 Male, age 76, left hemisphere 165.8
2771 Male, age 75, left hemisphere 151.2
1849 Female, age 91, right hemisphere 142.8
1885 Female, age 94, left hemisphere 140.2
1886 Female, age 67, right hemisphere 105.8
Corpus callosum, splenium (white matter)
nTPM: 129.0
2847 Female, age 67, right hemisphere 173.1
2104 Male, age 75, left hemisphere 122.7
2238 Female, age 94, right hemisphere 121.1
1946 Male, age 76, left hemisphere 98.9
Frontal eye field
nTPM: 89.4
2543 Male, age 74, left hemisphere 109.1
2761 Female, age 94, left hemisphere 83.6
2441 Male, age 75, left hemisphere 83.0
2147 Male, age 61, left hemisphere 81.9
Frontal operculum
nTPM: 113.0
2348 Male, age 75, left hemisphere 131.6
2030 Male, age 61, right hemisphere 118.5
2781 Female, age 85, right hemisphere 88.9
Fusiform gyrus
nTPM: 108.3
2074 Female, age 91, left hemisphere 169.9
2784 Female, age 85, left hemisphere 130.3
2431 Male, age 75, right hemisphere 102.6
1807 Male, age 76, left hemisphere 99.7
2112 Male, age 80, both hemispheres 96.5
2617 Female, age 94, left hemisphere 93.4
2433 Female, age 72, left hemisphere 65.9
Inferior frontal gyrus, opercular
nTPM: 83.9
2874 Female, age 85, right hemisphere 97.9
2875 Female, age 67, left hemisphere 93.2
2868 Male, age 75, right hemisphere 89.7
2869 Male, age 74, left hemisphere 89.0
2866 Male, age 61, right hemisphere 87.1
2871 Female, age 94, left hemisphere 84.4
2872 Female, age 94, right hemisphere 76.5
2867 Male, age 75, left hemisphere 76.0
2873 Female, age 85, left hemisphere 72.9
2865 Male, age 61, left hemisphere 72.2
Inferior parietal lobule
nTPM: 90.4
2606 Female, age 67, right hemisphere 132.1
2876 Male, age 76, right hemisphere 80.1
2599 Female, age 94, left hemisphere 78.2
2418 Male, age 75, left hemisphere 71.3
Inferior temporal gyrus
nTPM: 99.0
1965 Female, age 91, left hemisphere 114.8
1970 Female, age 85, right hemisphere 108.7
1808 Male, age 76, left hemisphere 99.8
1880 Male, age 80, right hemisphere 90.6
2430 Male, age 75, right hemisphere 90.0
2689 Female, age 94, right hemisphere 89.9
Intraparietal deep sulcus
nTPM: 101.4
2600 Female, age 94, right hemisphere 124.3
2102 Female, age 91, left hemisphere 116.9
2607 Female, age 67, right hemisphere 113.6
2669 Male, age 75, left hemisphere 99.4
2230 Male, age 61, right hemisphere 81.0
2798 Male, age 76, left hemisphere 73.2
Lingual gyrus
nTPM: 98.4
2073 Female, age 85, left hemisphere 120.1
1893 Male, age 76, left hemisphere 114.2
2618 Female, age 94, left hemisphere 100.3
2688 Male, age 75, right hemisphere 81.7
2838 Male, age 80, right hemisphere 75.6
Middle cingulate cortex
nTPM: 84.4
2640 Female, age 94, right hemisphere 98.0
2633 Male, age 74, left hemisphere 89.7
2539 Male, age 75, left hemisphere 82.3
2028 Female, age 85, left hemisphere 82.0
2357 Female, age 67, right hemisphere 69.9
Middle temporal gyrus
nTPM: 98.0
2611 Male, age 75, right hemisphere 106.0
2616 Female, age 94, left hemisphere 102.0
2034 Female, age 91, right hemisphere 95.9
1799 Male, age 76, left hemisphere 94.9
1819 Male, age 80, right hemisphere 91.4
Occipital cortex
nTPM: 79.8
2677 Female, age 67, right hemisphere 93.3
1842 Male, age 76, right hemisphere 84.1
2470 Male, age 75, right hemisphere 81.0
2608 Female, age 67, both hemispheres 74.1
2426 Male, age 75, midline 66.7
Occipital cortex (white matter)
nTPM: 93.6
2259 Male, age 75, midline 108.0
2257 Female, age 67, both hemispheres 79.2
Olfactory area
nTPM: 92.9
1805 Female, age 85, right hemisphere 122.5
2440 Male, age 75, left hemisphere 102.3
2352 Female, age 94, right hemisphere 87.2
2222 Female, age 67, right hemisphere 83.6
2756 Female, age 67, right hemisphere 82.5
2542 Male, age 74, left hemisphere 79.1
Olfactory tubercle
nTPM: 92.2
1846 Male, age 80, right hemisphere 109.2
2487 Female, age 94, left hemisphere 97.5
2856 Male, age 75, right hemisphere 87.0
1998 Female, age 91, both hemispheres 75.0
Orbitofrontal gyrus, anterior
nTPM: 93.2
2864 Female, age 67, left hemisphere 117.7
2862 Female, age 85, left hemisphere 95.1
2863 Female, age 85, right hemisphere 66.9
Paracentral lobule, anterior
nTPM: 79.8
1926 Male, age 61, left hemisphere 87.7
1776 Female, age 85, right hemisphere 85.4
1754 Male, age 75, left hemisphere 84.9
2638 Female, age 94, right hemisphere 79.5
2340 Female, age 67, right hemisphere 71.2
2474 Male, age 74, left hemisphere 70.1
Paracentral lobule, posterior
nTPM: 81.7
2551 Female, age 94, right hemisphere 102.9
1775 Female, age 85, right hemisphere 92.1
2446 Male, age 75, left hemisphere 78.1
1764 Male, age 74, right hemisphere 72.0
2345 Male, age 61, left hemisphere 63.6
Parahippocampal cortex (white matter)
nTPM: 113.2
2157 Female, age 91, both hemispheres 113.2
Parietal operculum
nTPM: 99.9
2719 Male, age 75, left hemisphere 133.1
1763 Male, age 74, left hemisphere 96.4
2552 Female, age 94, right hemisphere 93.8
2356 Female, age 67, right hemisphere 76.1
Parieto-insular cortex
nTPM: 84.6
2508 Female, age 94, right hemisphere 107.7
2671 Male, age 75, left hemisphere 87.9
2232 Male, age 61, right hemisphere 83.1
1976 Female, age 91, right hemisphere 78.9
2831 Male, age 76, right hemisphere 65.4
Parieto-occipital transitional area
nTPM: 95.4
2468 Male, age 75, left hemisphere 112.9
1784 Male, age 76, right hemisphere 98.6
2683 Female, age 67, left hemisphere 93.4
2270 Male, age 61, right hemisphere 88.6
2674 Female, age 94, right hemisphere 83.4
Parieto-temporal junction (white matter)
nTPM: 133.5
2774 Male, age 61, right hemisphere 175.4
1999 Female, age 67, right hemisphere 160.2
2121 Male, age 76, left hemisphere 125.0
2469 Male, age 75, right hemisphere 122.1
2770 Female, age 91, right hemisphere 117.2
1935 Female, age 94, right hemisphere 101.1
Piriform cortex
nTPM: 128.9
2153 Female, age 85, left hemisphere 129.4
2347 Male, age 75, right hemisphere 128.4
Postcentral gyrus
nTPM: 60.8
2533 Male, age 75, right hemisphere 60.8
Postcentral gyrus, dorsal
nTPM: 88.0
2350 Male, age 75, left hemisphere 97.3
2477 Female, age 94, right hemisphere 96.7
1836 Female, age 85, right hemisphere 95.3
2544 Male, age 74, left hemisphere 91.3
2151 Male, age 61, left hemisphere 81.4
2339 Female, age 67, right hemisphere 65.9
Postcentral gyrus, middle
nTPM: 79.9
2248 Male, age 61, left hemisphere 92.8
2146 Female, age 67, right hemisphere 83.5
1897 Female, age 85, right hemisphere 80.6
2444 Male, age 75, left hemisphere 71.5
2545 Male, age 74, left hemisphere 70.8
Postcentral gyrus, ventral
nTPM: 88.0
2836 Female, age 94, right hemisphere 91.6
2445 Male, age 75, left hemisphere 86.3
2024 Female, age 85, right hemisphere 86.2
Posterior cingulate cortex
nTPM: 88.5
2473 Male, age 75, left hemisphere 91.7
2553 Female, age 94, right hemisphere 89.0
1759 Male, age 74, right hemisphere 84.8
Posterior cingulate cortex, dorsal
nTPM: 93.1
2556 Female, age 67, right hemisphere 118.2
2343 Male, age 61, left hemisphere 112.6
2641 Female, age 94, right hemisphere 89.8
2540 Male, age 75, right hemisphere 88.9
2076 Female, age 85, right hemisphere 76.9
2634 Male, age 74, left hemisphere 71.9
Posterior cingulate cortex, ventral
nTPM: 92.8
2448 Female, age 67, right hemisphere 109.2
2541 Male, age 75, right hemisphere 102.5
1994 Female, age 85, right hemisphere 97.2
2635 Male, age 74, left hemisphere 89.4
1762 Female, age 94, right hemisphere 84.7
2346 Male, age 61, left hemisphere 73.7
Posterior insular cortex
nTPM: 84.1
2597 Male, age 75, left hemisphere 95.9
2511 Female, age 67, right hemisphere 90.0
2832 Female, age 91, right hemisphere 88.3
2603 Female, age 94, left hemisphere 81.3
1823 Male, age 76, right hemisphere 74.8
2231 Male, age 61, left hemisphere 74.6
Precentral gyrus
nTPM: 75.1
2557 Male, age 75, right hemisphere 75.1
Precentral gyrus, dorsal
nTPM: 81.7
2476 Female, age 94, right hemisphere 89.2
2354 Female, age 67, right hemisphere 83.8
2442 Male, age 75, left hemisphere 77.7
1756 Male, age 74, left hemisphere 76.2
Precentral gyrus, middle
nTPM: 85.0
2475 Male, age 74, right hemisphere 113.4
2549 Female, age 94, right hemisphere 86.1
2443 Male, age 75, left hemisphere 75.8
1909 Male, age 61, left hemisphere 75.1
1969 Female, age 67, right hemisphere 74.5
Precentral gyrus, ventral
nTPM: 81.0
2550 Female, age 94, right hemisphere 105.8
2630 Male, age 75, left hemisphere 77.4
2678 Male, age 74, left hemisphere 75.3
2662 Female, age 67, right hemisphere 65.5
Precuneus
nTPM: 99.2
1780 Female, age 91, right hemisphere 119.7
2467 Male, age 75, right hemisphere 116.0
1782 Male, age 76, right hemisphere 95.2
2510 Female, age 67, right hemisphere 94.9
2594 Male, age 61, left hemisphere 86.1
2673 Female, age 94, right hemisphere 83.1
Premotor cortex, dorsal
nTPM: 90.4
2554 Female, age 67, right hemisphere 113.2
2536 Male, age 75, left hemisphere 100.0
2027 Male, age 61, left hemisphere 86.0
2631 Male, age 74, left hemisphere 78.3
1878 Female, age 85, right hemisphere 74.7
Premotor cortex, ventral
nTPM: 75.7
2349 Male, age 75, left hemisphere 97.1
2637 Female, age 94, right hemisphere 82.2
1881 Female, age 85, right hemisphere 75.4
1779 Male, age 61, left hemisphere 67.7
1757 Male, age 74, left hemisphere 65.9
1777 Female, age 67, left hemisphere 65.6
Retrosplenial cortex
nTPM: 118.8
1914 Male, age 76, right hemisphere 177.3
2675 Female, age 94, left hemisphere 90.5
1951 Male, age 61, right hemisphere 88.5
Somatomor cortex, precentral gyrus (white matter)
nTPM: 93.3
2439 Male, age 75, right hemisphere 93.3
Somatosensory cortex, postcentral gyrus, ventral (white matter)
nTPM: 80.6
2623 Male, age 75, right hemisphere 80.6
Subcentral gyrus, S2
nTPM: 92.7
2555 Female, age 67, right hemisphere 128.9
1964 Female, age 85, right hemisphere 99.9
2072 Male, age 61, left hemisphere 88.6
2351 Male, age 75, left hemisphere 86.0
2762 Male, age 74, left hemisphere 77.0
2839 Female, age 94, right hemisphere 75.9
Superior parietal lobule
nTPM: 97.7
2605 Female, age 67, right hemisphere 127.6
1800 Male, age 76, right hemisphere 102.4
2672 Female, age 94, right hemisphere 89.3
1992 Female, age 91, right hemisphere 85.2
2229 Male, age 61, right hemisphere 83.9
Superior temporal gyrus
nTPM: 95.8
1844 Female, age 91, left hemisphere 119.6
2025 Male, age 80, right hemisphere 112.3
2615 Female, age 94, left hemisphere 86.1
1843 Male, age 76, left hemisphere 80.5
2687 Male, age 75, right hemisphere 80.5
Supplementary motor cortex
nTPM: 78.1
2548 Female, age 94, right hemisphere 95.0
1993 Male, age 61, left hemisphere 78.9
2537 Male, age 75, left hemisphere 75.9
2632 Male, age 74, left hemisphere 62.7
Supramarginal gyrus
nTPM: 96.6
1798 Male, age 76, right hemisphere 107.3
2513 Female, age 72, left hemisphere 96.0
2601 Female, age 94, left hemisphere 96.0
1991 Female, age 91, right hemisphere 95.2
2415 Male, age 61, left hemisphere 88.2
Temporal pole
nTPM: 107.7
2518 Male, age 75, right hemisphere 119.9
1832 Female, age 91, left hemisphere 119.7
1826 Male, age 76, right hemisphere 107.6
2612 Female, age 94, left hemisphere 101.7
1853 Female, age 85, right hemisphere 89.8
Temporal white matter
nTPM: 157.4
1801 Male, age 76, left hemisphere 188.7
2524 Female, age 85, left hemisphere 183.7
2523 Female, age 94, left hemisphere 172.1
2736 Female, age 91, right hemisphere 137.7
2254 Male, age 75, right hemisphere 104.7
Temporo-insular cortex, parainsular gyrus
nTPM: 110.5
2264 Female, age 91, right hemisphere 164.9
2598 Male, age 75, left hemisphere 107.6
1802 Male, age 76, left hemisphere 107.2
2416 Male, age 61, right hemisphere 98.2
2512 Female, age 67, right hemisphere 94.8
2676 Female, age 94, right hemisphere 90.2
Temporo-occipital transitional zone
nTPM: 103.7
2251 Female, age 85, right hemisphere 132.9
1793 Male, age 80, right hemisphere 104.4
1900 Male, age 76, left hemisphere 73.8
Transversal temporal gyrus, anterior
nTPM: 93.2
2610 Male, age 75, right hemisphere 111.3
1910 Male, age 80, right hemisphere 101.4
1809 Male, age 76, right hemisphere 86.0
1888 Female, age 91, left hemisphere 85.8
2522 Female, age 94, left hemisphere 81.7
Transversal temporal gyrus, posterior
nTPM: 97.7
1967 Female, age 91, right hemisphere 153.3
2520 Male, age 75, right hemisphere 96.3
2614 Female, age 94, left hemisphere 89.6
1922 Male, age 76, left hemisphere 79.3
2833 Male, age 80, right hemisphere 70.0

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

23.6
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 22.6
1510 Male, age 61, left hemisphere 37.3
1517 Female, age 67, left hemisphere 36.7
1512 Male, age 75, left hemisphere 28.7
1511 Male, age 61, right hemisphere 25.8
1514 Male, age 74, right hemisphere 21.0
1515 Female, age 94, right hemisphere 20.3
1516 Female, age 85, left hemisphere 16.6
1518 Female, age 67, right hemisphere 16.1
1513 Male, age 74, left hemisphere 0.7
Anterior cingulate gyrus, pregenual-ventral
nTPM: 14.1
1520 Male, age 75, right hemisphere 26.6
1519 Male, age 61, left hemisphere 26.2
1521 Male, age 74, left hemisphere 16.9
1522 Male, age 74, right hemisphere 0.9
1523 Female, age 67, left hemisphere 0.0
Anterior cingulate gyrus, subgenual
nTPM: 23.6
1524 Male, age 61, left hemisphere 35.4
1526 Male, age 75, right hemisphere 33.0
1527 Male, age 74, left hemisphere 30.5
1525 Male, age 75, left hemisphere 28.9
1528 Male, age 74, right hemisphere 28.1
1529 Female, age 85, left hemisphere 9.4
1530 Female, age 67, right hemisphere 0.3
Dorsolateral prefrontal cortex
nTPM: 8.3
1450 Female, age 67, right hemisphere 18.5
1448 Female, age 94, right hemisphere 10.1
1449 Female, age 85, right hemisphere 8.5
1446 Male, age 74, right hemisphere 7.4
1445 Male, age 75, right hemisphere 4.8
1447 Female, age 94, left hemisphere 4.8
1444 Male, age 75, left hemisphere 3.7
Dorsomedial prefrontal cortex
nTPM: 8.8
1439 Male, age 61, left hemisphere 15.4
1440 Male, age 61, right hemisphere 10.9
1442 Male, age 75, right hemisphere 10.4
1441 Male, age 75, left hemisphere 6.8
1443 Female, age 67, right hemisphere 0.3
Frontomarginal cortex
nTPM: 6.0
1469 Female, age 94, left hemisphere 12.9
1471 Female, age 85, left hemisphere 10.2
1470 Female, age 94, right hemisphere 10.1
1468 Male, age 74, left hemisphere 7.1
1466 Male, age 61, right hemisphere 5.7
1465 Male, age 61, left hemisphere 5.3
1467 Male, age 75, right hemisphere 2.7
1472 Female, age 67, left hemisphere 0.3
1473 Female, age 67, right hemisphere 0.0
Frontopolar cortex
nTPM: 7.0
1458 Male, age 61, left hemisphere 12.5
1461 Male, age 75, right hemisphere 8.9
1462 Female, age 94, left hemisphere 8.1
1459 Male, age 61, right hemisphere 7.3
1460 Male, age 75, left hemisphere 7.0
1463 Female, age 67, left hemisphere 5.1
1464 Female, age 67, right hemisphere 0.1
Gyrus rectus
nTPM: 5.3
1478 Female, age 94, left hemisphere 22.2
1479 Female, age 94, right hemisphere 11.3
1480 Female, age 85, left hemisphere 4.2
1475 Male, age 61, right hemisphere 4.0
1477 Male, age 75, right hemisphere 0.2
1476 Male, age 75, left hemisphere 0.1
1474 Male, age 61, left hemisphere 0.0
1481 Female, age 67, left hemisphere 0.0
Inferior frontal gyrus, orbital
nTPM: 19.5
1505 Male, age 74, right hemisphere 44.0
1501 Male, age 61, right hemisphere 37.3
1500 Male, age 61, left hemisphere 28.7
1503 Male, age 75, right hemisphere 27.9
1506 Female, age 94, left hemisphere 23.7
1508 Female, age 85, right hemisphere 19.5
1504 Male, age 74, left hemisphere 12.2
1509 Female, age 67, right hemisphere 0.7
1502 Male, age 75, left hemisphere 0.2
1507 Female, age 85, left hemisphere 0.2
Inferior frontal gyrus, triangular
nTPM: 20.8
1542 Male, age 61, left hemisphere 29.2
1544 Male, age 75, right hemisphere 28.2
1549 Female, age 67, left hemisphere 24.6
1547 Female, age 85, left hemisphere 23.7
1546 Female, age 94, right hemisphere 19.6
1543 Male, age 61, right hemisphere 18.0
1545 Male, age 74, right hemisphere 16.0
1548 Female, age 85, right hemisphere 7.3
Orbitofrontal gyrus, lateral
nTPM: 16.2
1497 Female, age 85, left hemisphere 27.0
1495 Female, age 94, left hemisphere 25.0
1496 Female, age 94, right hemisphere 21.9
1493 Male, age 61, right hemisphere 19.4
1499 Female, age 67, right hemisphere 10.8
1498 Female, age 85, right hemisphere 8.9
1494 Male, age 75, left hemisphere 0.4
Orbitofrontal gyrus, medial
nTPM: 4.5
1482 Male, age 61, left hemisphere 9.7
1491 Female, age 67, left hemisphere 6.2
1489 Female, age 85, left hemisphere 5.8
1488 Female, age 94, right hemisphere 5.7
1487 Female, age 94, left hemisphere 5.1
1490 Female, age 85, right hemisphere 5.0
1483 Male, age 75, left hemisphere 4.6
1484 Male, age 75, right hemisphere 4.3
1492 Female, age 67, right hemisphere 2.8
1485 Male, age 74, left hemisphere 0.0
1486 Male, age 74, right hemisphere 0.0
Orbitofrontal gyrus, posterior
nTPM: 17.2
1537 Female, age 94, right hemisphere 28.8
1535 Male, age 74, left hemisphere 25.7
1536 Female, age 94, left hemisphere 22.8
1538 Female, age 85, left hemisphere 21.8
1531 Male, age 61, left hemisphere 20.3
1539 Female, age 85, right hemisphere 19.2
1532 Male, age 61, right hemisphere 18.4
1534 Male, age 75, right hemisphere 16.7
1533 Male, age 75, left hemisphere 15.0
1541 Female, age 67, right hemisphere 0.5
1540 Female, age 67, left hemisphere 0.4
Subcallosal gyrus
nTPM: 7.2
1557 Female, age 94, right hemisphere 15.5
1556 Female, age 94, left hemisphere 13.7
1553 Male, age 75, right hemisphere 11.7
1550 Male, age 61, left hemisphere 10.6
1555 Male, age 74, right hemisphere 8.0
1551 Male, age 61, right hemisphere 7.0
1552 Male, age 75, left hemisphere 6.7
1554 Male, age 74, left hemisphere 6.3
1559 Female, age 85, right hemisphere 3.9
1561 Female, age 67, right hemisphere 3.3
1560 Female, age 67, left hemisphere 0.1
1558 Female, age 85, left hemisphere 0.0
Superior frontal gyrus
nTPM: 5.1
1563 Male, age 61, right hemisphere 17.6
1562 Male, age 61, left hemisphere 11.6
1567 Female, age 94, left hemisphere 7.5
1564 Male, age 75, left hemisphere 7.1
1568 Female, age 94, right hemisphere 4.6
1569 Female, age 85, left hemisphere 2.5
1566 Male, age 74, right hemisphere 0.3
1565 Male, age 75, right hemisphere 0.1
1570 Female, age 85, right hemisphere 0.1
1571 Female, age 67, right hemisphere 0.1
Temporal cortex
nTPM: 7.6
1593 Male, age 74, right hemisphere 15.4
1595 Female, age 94, right hemisphere 14.2
1594 Female, age 94, left hemisphere 9.7
1596 Female, age 85, right hemisphere 5.3
1590 Male, age 61, right hemisphere 4.9
1592 Male, age 74, left hemisphere 3.6
1591 Male, age 75, right hemisphere 0.1
Ventrolateral prefrontal cortex
nTPM: 2.8
1454 Female, age 94, left hemisphere 8.6
1451 Male, age 75, right hemisphere 6.5
1453 Male, age 74, right hemisphere 3.6
1456 Female, age 67, left hemisphere 0.7
1457 Female, age 67, right hemisphere 0.2
1452 Male, age 74, left hemisphere 0.1
1455 Female, age 85, right hemisphere 0.1
Ventromedial prefrontal cortex
nTPM: 8.9
1435 Female, age 94, right hemisphere 14.6
1432 Male, age 61, left hemisphere 13.7
1433 Male, age 61, right hemisphere 11.1
1434 Male, age 75, right hemisphere 8.2
1438 Female, age 67, left hemisphere 8.2
1436 Female, age 85, left hemisphere 3.6
1437 Female, age 85, right hemisphere 3.2

CEREBRAL CORTEX - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

7.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 3.3
FF:10163-103B1 76 years, female 3.3
Postcentral gyrus
Scaled Tags Per Million: 4.3
FF:10032-101E5 44-52 years, mixed 4.3
Frontal lobe
Scaled Tags Per Million: 4.0
FF:10040-101F4 32-61 years, mixed 4.0
Insula
Scaled Tags Per Million: 4.1
FF:10039-101F3 20-68 years, mixed 4.1
Medial frontal gyrus
Scaled Tags Per Million: 4.5
FF:10150-102I6 76 years, female 4.5
Medial temporal gyrus
Scaled Tags Per Million: 2.8
FF:10156-103A3 76 years, female 3.5
FF:10183-103D3 60 years, female 2.1
Occipital lobe
Scaled Tags Per Million: 2.3
FF:10076-102A4 27 years, male 2.3
Occipital pole
Scaled Tags Per Million: 7.5
FF:10036-101E9 22-68 years, mixed 7.5
Paracentral gyrus
Scaled Tags Per Million: 4.7
FF:10035-101E8 22-69 years, mixed 4.7
Parietal lobe
Scaled Tags Per Million: 4.0
FF:10171-103B9 60 years, female 6.1
FF:10034-101E7 35-89 years, mixed 3.2
FF:10157-103A4 76 years, female 2.8
Temporal lobe
Scaled Tags Per Million: 4.9
FF:10031-101E4 32-61 years, mixed 4.9

CEREBRAL CORTEX - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

13.6
Macaque sample Sample description nTPM
Angular gyrus
nTPM: 12.4
Samples: 1

Max nTPM: 12.4
Min nTPM: 12.4
Sample A 12.4
Claustrum
nTPM: 13.6
Samples: 1

Max nTPM: 13.6
Min nTPM: 13.6
Sample B 13.6
Fusiform gyrus
nTPM: 9.3
Samples: 2

Max nTPM: 16.6
Min nTPM: 1.9
Sample A 1.9
Sample B 16.6
Inferior temporal gyrus
nTPM: 9.2
Samples: 2

Max nTPM: 11.3
Min nTPM: 7.1
Sample A 7.1
Sample B 11.3
Middle temporal gyrus
nTPM: 11.1
Samples: 2

Max nTPM: 11.8
Min nTPM: 10.4
Sample A 11.8
Sample B 10.4
Postcentral gyrus
nTPM: 13.3
Samples: 2

Max nTPM: 20.3
Min nTPM: 6.3
Sample A 6.3
Sample B 20.3
Posterior cingulate cortex
nTPM: 7.6
Samples: 2

Max nTPM: 10.2
Min nTPM: 4.9
Sample A 4.9
Sample B 10.2
Precentral gyrus
nTPM: 13.1
Samples: 3

Max nTPM: 17.0
Min nTPM: 9.0
Sample A 9.0
Sample B 13.4
Sample C 17.0
Superior parietal lobule
nTPM: 8.2
Samples: 2

Max nTPM: 10.8
Min nTPM: 5.5
Sample A 5.5
Sample B 10.8
Superior temporal gyrus
nTPM: 9.7
Samples: 2

Max nTPM: 12.6
Min nTPM: 6.8
Sample A 6.8
Sample B 12.6
Supramarginal gyrus
nTPM: 9.3
Samples: 2

Max nTPM: 11.5
Min nTPM: 7.0
Sample A 7.0
Sample B 11.5
Gyrus rectus
nTPM: 9.6
Samples: 2

Max nTPM: 11.2
Min nTPM: 8.0
Sample A 8.0
Sample B 11.2
Insular cortex
nTPM: 12.0
Samples: 2

Max nTPM: 16.8
Min nTPM: 7.2
Sample A 7.2
Sample B 16.8
Superior frontal gyrus
nTPM: 11.7
Samples: 2

Max nTPM: 16.7
Min nTPM: 6.7
Sample A 6.7
Sample B 16.7

CEREBRAL CORTEX - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

88.0
Pig sample Sample description nTPM
Occipital cortex
nTPM: 85.9
Samples: 4

Max nTPM: 96.4
Min nTPM: 76.1
Sample A Female 91.2
Sample B Female 76.1
Sample C Male 96.4
Sample D Male 79.7
Retrosplenial cortex
nTPM: 62.1
Samples: 4

Max nTPM: 69.5
Min nTPM: 54.0
Sample A Female 69.5
Sample B Female 54.0
Sample C Male 67.6
Sample D Male 57.4
Cingulate cortex
nTPM: 69.3
Samples: 4

Max nTPM: 95.1
Min nTPM: 48.5
Sample A Female 95.1
Sample B Female 53.4
Sample C Male 80.2
Sample D Male 48.5
Insular cortex
nTPM: 55.3
Samples: 4

Max nTPM: 76.2
Min nTPM: 43.1
Sample A Female 76.2
Sample B Female 45.3
Sample C Male 56.5
Sample D Male 43.1
Motor cortex
nTPM: 70.4
Samples: 4

Max nTPM: 83.7
Min nTPM: 55.3
Sample A Female 78.9
Sample B Female 63.8
Sample C Male 83.7
Sample D Male 55.3
Prefrontal cortex
nTPM: 65.1
Samples: 4

Max nTPM: 73.1
Min nTPM: 57.0
Sample A Female 73.1
Sample B Female 65.6
Sample C Male 64.8
Sample D Male 57.0
Somatosensory cortex
nTPM: 87.9
Samples: 3

Max nTPM: 92.9
Min nTPM: 85.4
Sample B Female 85.4
Sample C Male 85.5
Sample D Male 92.9
Temporal cortex
nTPM: 71.3
Samples: 3

Max nTPM: 88.3
Min nTPM: 56.8
Sample A Female 88.3
Sample B Female 56.8
Sample D Male 68.7

CEREBRAL CORTEX - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

41.2
Mouse sample Sample description nTPM
Motor and prefrontal cortex
nTPM: 41.2
Samples: 4

Max nTPM: 47.2
Min nTPM: 31.4
Sample A 47.2
Sample B 40.4
Sample C 45.7
Sample D 31.4
Retrosplenial and cingulate cortex
nTPM: 41.1
Samples: 3

Max nTPM: 43.9
Min nTPM: 38.2
Sample A 41.1
Sample B 43.9
Sample C 38.2
Somatosensory cortex
nTPM: 40.0
Samples: 4

Max nTPM: 44.1
Min nTPM: 34.8
Sample A 43.9
Sample B 34.8
Sample C 44.1
Sample D 37.2
Visual cortex
nTPM: 40.2
Samples: 4

Max nTPM: 42.2
Min nTPM: 38.9
Sample A 42.2
Sample B 40.0
Sample C 38.9
Sample D 39.6

CEREBRAL CORTEX - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

39.3
Rat sample Sample description nTPM
Occipital cortex
nTPM: 39.4
Samples: 4

Max nTPM: 41.3
Min nTPM: 37.2
Sample A 37.2
Sample A 39.4
Sample A 41.3
Sample A 39.6
Retrosplenial and cingulate cortex
nTPM: 34.6
Samples: 4

Max nTPM: 37.7
Min nTPM: 31.8
Sample A 31.8
Sample A 34.6
Sample B 37.7
Sample A 34.1
Somatosensory cortex
nTPM: 33.2
Samples: 4

Max nTPM: 35.9
Min nTPM: 30.9
Sample A 35.2
Sample A 30.9
Sample A 35.9
Sample A 30.9

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