Some proteins are expressed periodically during a specific stage of the cell cycle or as a response to various stimuli. As a result, at any given time some cells express the protein of interest and some do not. In the Cell Atlas we denote these images as single-cell variation (SCV). An example of a protein with such variations is CCNB1.
CCNB1, shown here in U-251 MG cells, is essential for cellular proliferation. The abundance of CCNB1 oscillates across the cell cycle, and peaks during G2/M phase. CCNB1 is expressed in the cytoplasm during interphase and translocate to the nucleus during G2/M transition...Read more
January 23, 2019 - January 24, 2019
Dr. Cecilia Lindskog, Director Tissue Atlas, will give a presentation on "The Human Protein Atlas - Mapping Through Transcriptomics and Proteomics" at the Festival of Genomics held at the Business Design Centre in London. The talk is at 13:00 on Thursday, January 24.Programme
February 24, 2019 - February 26, 2019
Dr. Emma Lundberg, will give a presentation on "Dissecting spatiotemporal variations of the human proteome" at the Cell Symposium "Single Cells: Technology to Biology" held at the A* STAR Genome Institute of Singapore. She will present on Monday February 25, at 16:15.Programme