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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
ANTIBODIES
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VALIDATION
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:129.5 nTPM
HPA Brain:66.1 nTPM
GTEx:129.5 nTPM
FANTOM5:72.5 Scaled Tags Per Million
Pig:36.4 nTPM
Mouse:173.9 nTPM
Allen mouse:2.0 Expression energy

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

66.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 51.0
2019 Male, age 18, unknown 75.5
2411 Female, age 72, unknown 58.8
1827 Male, age 72, unknown 55.8
2219 Male, age 76, both hemispheres 53.6
1870 Female, age 42, unknown 50.8
2828 Female, age 72, unknown 48.9
2586 Male, age 75, left hemisphere 48.3
1833 Male, age 53, unknown 42.8
1830 Male, age 51, unknown 40.9
2666 Male, age 74, left hemisphere 34.2
Dorsal raphe nucleus
nTPM: 64.0
2298 Female, age 72, unknown 92.8
1828 Male, age 53, unknown 63.4
2750 Male, age 76, both hemispheres 59.0
2047 Male, age 72, unknown 58.5
2016 Female, age 72, unknown 46.5
Inferior colliculus
nTPM: 55.3
2097 Female, age 72, unknown 67.3
1890 Male, age 53, unknown 61.6
1848 Female, age 42, unknown 52.1
2849 Male, age 72, unknown 40.1
Median raphe nucleus
nTPM: 59.0
2220 Male, age 76, midline 59.0
Periaquaductal grey, anterior
nTPM: 57.8
1795 Male, age 51, unknown 61.9
1947 Male, age 18, unknown 56.5
2502 Female, age 75, unknown 54.9
Periaquaductal grey, dorsal
nTPM: 45.1
1840 Male, age 53, unknown 49.5
2850 Male, age 76, both hemispheres 44.2
2464 Female, age 72, unknown 43.9
1831 Male, age 72, unknown 42.7
Periaquaductal grey, lateral
nTPM: 50.6
2272 Male, age 74, both hemispheres 62.8
2140 Male, age 76, both hemispheres 46.1
2053 Male, age 18, unknown 42.8
Pretectal area
nTPM: 66.1
2007 Male, age 72, unknown 85.9
1816 Male, age 51, unknown 81.9
1817 Female, age 42, unknown 78.0
1944 Female, age 72, unknown 74.3
2273 Male, age 74, both hemispheres 70.0
2667 Female, age 75, unknown 66.2
2224 Female, age 72, unknown 66.0
1815 Male, age 53, unknown 59.5
2316 Male, age 76, right hemisphere 51.1
2407 Male, age 75, both hemispheres 49.3
2825 Male, age 18, unknown 44.2
Red nucleus
nTPM: 54.4
2725 Female, age 75, unknown 69.6
1821 Female, age 72, unknown 67.9
2785 Male, age 18, unknown 66.7
2227 Male, age 72, unknown 55.5
2769 Male, age 72, unknown 54.3
2823 Male, age 76, right hemisphere 53.7
1865 Male, age 51, unknown 52.2
2503 Female, age 72, unknown 52.0
1904 Male, age 53, unknown 50.6
1954 Female, age 42, unknown 49.7
2588 Male, age 74, left hemisphere 42.8
2584 Male, age 75, left hemisphere 38.2
Substantia nigra
nTPM: 64.1
1916 Female, age 42, unknown 79.8
2241 Male, age 72, unknown 79.1
1889 Female, age 72, unknown 77.9
1851 Male, age 51, unknown 75.1
1941 Male, age 53, unknown 72.5
2409 Female, age 72, unknown 55.2
2665 Male, age 74, both hemispheres 53.7
2583 Male, age 75, right hemisphere 52.1
2590 Female, age 75, unknown 47.8
2699 Male, age 18, unknown 47.4
Superior colliculus
nTPM: 53.6
2087 Female, age 72, unknown 70.6
2261 Male, age 18, unknown 63.9
1895 Male, age 76, right hemisphere 63.1
1796 Male, age 53, unknown 60.9
2587 Male, age 74, left hemisphere 54.6
2668 Female, age 75, unknown 54.5
1839 Male, age 51, unknown 46.8
1913 Female, age 42, unknown 46.6
1995 Male, age 72, unknown 40.6
2664 Male, age 75, both hemispheres 34.3
Ventral tegmental area
nTPM: 58.6
1915 Female, age 42, unknown 68.4
2218 Male, age 76, both hemispheres 67.7
2410 Female, age 72, unknown 66.8
2223 Female, age 72, unknown 53.4
1942 Male, age 51, unknown 49.8
2021 Male, age 53, unknown 45.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

129.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 129.5
Samples: 139

Max nTPM: 318.7
Min nTPM: 55.7
Std nTPM: 44.4
Median nTPM: 120.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 318.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 257.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 255.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 248.8
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 236.6
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 235.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 234.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 218.3
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 212.0
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 206.0
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 205.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 202.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 199.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 192.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 186.1
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 184.9
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 183.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 175.1
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 173.6
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 170.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 168.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 168.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 164.5
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 163.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 163.2
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 162.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 161.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 160.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 159.0
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 158.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 157.0
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 156.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 155.3
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 154.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 152.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 152.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 151.4
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 149.0
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 146.6
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 141.7
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 138.4
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 137.9
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 137.9
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 137.0
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 136.6
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 135.8
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 135.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 134.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 133.7
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 133.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 132.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 132.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 131.7
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 131.2
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 129.6
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 129.5
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 129.2
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 127.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 127.3
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 126.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 125.9
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 125.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 125.5
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 124.6
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 122.5
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 122.2
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 121.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 120.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 120.4
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 120.1
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 119.8
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 118.2
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 116.4
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 112.7
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 112.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 111.9
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 111.6
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 110.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 110.2
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 109.5
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 109.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 109.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 107.8
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 107.7
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 106.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 106.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 106.4
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 106.2
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 105.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 105.7
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 104.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 104.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 104.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 104.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 104.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 104.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 103.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 103.3
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 102.5
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 101.9
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 101.7
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 101.5
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 100.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 99.2
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 98.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 98.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 98.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 96.8
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 96.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 96.1
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 95.8
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 94.8
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 94.6
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 94.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 94.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 93.9
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 92.6
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 92.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 92.2
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 89.9
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 88.4
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 88.0
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 86.6
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 85.2
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 84.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 83.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 82.8
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 82.4
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 81.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 80.7
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 80.7
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 80.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 78.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 78.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 73.2
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 72.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 71.8
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 67.1
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 55.7
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

72.5
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 72.5
FF:10158-103A5 76 years, female 72.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

36.4
Pig sample Sample description nTPM
Substantia nigra
nTPM: 27.5
Samples: 4

Max nTPM: 39.1
Min nTPM: 19.6
Sample A Female 39.1
Sample B Female 21.2
Sample C Male 30.2
Sample D Male 19.6
Midbrain
nTPM: 31.4
Samples: 4

Max nTPM: 39.7
Min nTPM: 26.7
Sample A Female 28.2
Sample B Female 26.7
Sample C Male 39.7
Sample D Male 30.8
Periaqueductal gray
nTPM: 24.5
Samples: 3

Max nTPM: 27.9
Min nTPM: 22.3
Sample B Female 23.2
Sample C Male 27.9
Sample D Male 22.3
Superior colliculi
nTPM: 36.4
Samples: 4

Max nTPM: 46.1
Min nTPM: 27.2
Sample A Female 41.9
Sample B Female 27.2
Sample C Male 46.1
Sample D Male 30.4

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

173.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 173.9
Samples: 4

Max nTPM: 185.8
Min nTPM: 164.2
Sample A Male 175.7
Sample B Male 185.8
Sample C Female 169.9
Sample D Female 164.2

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

2.0
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 2.0
69174341 Antisense, RP_050329_02_B11, Mouse strain C57BL/6J (56 days, male) 2.0

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