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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS HIPPOCAMPAL FORMATION HYPOTHALAMUS MEDULLA OBLONGATA
MIDBRAIN OLFACTORY BULB PITUITARY GLAND PONS RETINA SPINAL CORD THALAMUS WHITE MATTER
Brain proteome
Midbrain
MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.

Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.

If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.

The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.

Scroll down to view mRNA expression data in more detail.
Consensus:40.8 nTPM
HPA Brain:49.1 nTPM
GTEx:40.8 nTPM
FANTOM5:94.8 Scaled Tags Per Million
Pig:68.9 nTPM
Mouse:266.6 nTPM
Allen mouse:19.6 Expression energy

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

49.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 43.2
2019 Male, age 18, unknown 56.5
2586 Male, age 75, left hemisphere 52.4
1833 Male, age 53, unknown 46.1
1830 Male, age 51, unknown 44.5
1870 Female, age 42, unknown 41.6
2411 Female, age 72, unknown 41.5
2666 Male, age 74, left hemisphere 38.7
2219 Male, age 76, both hemispheres 37.9
2828 Female, age 72, unknown 37.4
1827 Male, age 72, unknown 35.6
Dorsal raphe nucleus
nTPM: 32.7
2750 Male, age 76, both hemispheres 36.9
1828 Male, age 53, unknown 34.8
2016 Female, age 72, unknown 31.3
2298 Female, age 72, unknown 30.9
2047 Male, age 72, unknown 29.8
Inferior colliculus
nTPM: 38.8
2097 Female, age 72, unknown 40.6
1848 Female, age 42, unknown 38.7
1890 Male, age 53, unknown 38.0
2849 Male, age 72, unknown 37.8
Median raphe nucleus
nTPM: 30.1
2220 Male, age 76, midline 30.1
Periaquaductal grey, anterior
nTPM: 33.9
2502 Female, age 75, unknown 38.5
1947 Male, age 18, unknown 34.0
1795 Male, age 51, unknown 29.3
Periaquaductal grey, dorsal
nTPM: 29.9
2464 Female, age 72, unknown 38.0
1831 Male, age 72, unknown 28.8
1840 Male, age 53, unknown 28.1
2850 Male, age 76, both hemispheres 24.5
Periaquaductal grey, lateral
nTPM: 28.6
2272 Male, age 74, both hemispheres 32.5
2053 Male, age 18, unknown 30.1
2140 Male, age 76, both hemispheres 23.1
Pretectal area
nTPM: 38.0
1817 Female, age 42, unknown 50.3
2007 Male, age 72, unknown 48.7
1815 Male, age 53, unknown 45.4
1944 Female, age 72, unknown 42.5
1816 Male, age 51, unknown 40.3
2407 Male, age 75, both hemispheres 38.0
2667 Female, age 75, unknown 34.2
2316 Male, age 76, right hemisphere 31.6
2825 Male, age 18, unknown 30.7
2273 Male, age 74, both hemispheres 29.2
2224 Female, age 72, unknown 27.1
Red nucleus
nTPM: 49.1
1865 Male, age 51, unknown 55.0
1904 Male, age 53, unknown 54.2
2785 Male, age 18, unknown 53.8
1954 Female, age 42, unknown 53.3
1821 Female, age 72, unknown 51.3
2503 Female, age 72, unknown 50.1
2725 Female, age 75, unknown 49.5
2769 Male, age 72, unknown 47.4
2588 Male, age 74, left hemisphere 46.8
2227 Male, age 72, unknown 46.7
2584 Male, age 75, left hemisphere 42.6
2823 Male, age 76, right hemisphere 38.7
Substantia nigra
nTPM: 43.7
2241 Male, age 72, unknown 49.4
2409 Female, age 72, unknown 48.8
2583 Male, age 75, right hemisphere 48.4
1851 Male, age 51, unknown 46.8
1889 Female, age 72, unknown 45.0
1916 Female, age 42, unknown 43.3
2665 Male, age 74, both hemispheres 42.0
1941 Male, age 53, unknown 39.2
2699 Male, age 18, unknown 37.3
2590 Female, age 75, unknown 36.7
Superior colliculus
nTPM: 40.2
2664 Male, age 75, both hemispheres 46.2
2668 Female, age 75, unknown 44.8
2087 Female, age 72, unknown 43.0
1913 Female, age 42, unknown 42.3
1995 Male, age 72, unknown 40.0
1839 Male, age 51, unknown 38.1
2587 Male, age 74, left hemisphere 38.0
1895 Male, age 76, right hemisphere 37.5
2261 Male, age 18, unknown 36.4
1796 Male, age 53, unknown 36.2
Ventral tegmental area
nTPM: 37.6
2410 Female, age 72, unknown 49.0
1915 Female, age 42, unknown 38.3
2223 Female, age 72, unknown 37.7
2218 Male, age 76, both hemispheres 36.3
1942 Male, age 51, unknown 33.0
2021 Male, age 53, unknown 31.4

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

40.8
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 40.8
Samples: 139

Max nTPM: 67.7
Min nTPM: 25.8
Std nTPM: 7.5
Median nTPM: 39.3
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 67.7
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 67.5
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 62.1
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 61.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 56.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 54.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 54.1
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 54.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 53.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 53.1
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 53.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 52.8
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 52.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 51.8
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 50.3
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 49.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 49.1
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 48.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 48.6
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 48.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 48.4
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 48.3
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 47.8
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 47.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 47.6
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 47.6
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 47.6
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 47.5
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 46.9
GTEX-1IKOH-0011-R2a-SM-CMKHO 60-69 years, female 46.9
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 46.9
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 46.8
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 46.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 46.2
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 45.1
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 44.6
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 44.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 44.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 43.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 43.6
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 43.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 43.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 42.9
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 42.9
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 42.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 42.6
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 42.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 42.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 42.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 42.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 41.9
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 41.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 41.4
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 41.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 41.2
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 40.8
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 40.5
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 40.3
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 40.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 40.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 40.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 39.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 39.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 39.6
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 39.5
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 39.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 39.5
GTEX-N7MT-0011-R2a-SM-2I3GI 60-69 years, female 39.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 39.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 39.3
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 39.1
GTEX-18464-0011-R2a-SM-731AL 50-59 years, male 39.0
GTEX-T5JC-0011-R2A-SM-32PLZ 20-29 years, male 39.0
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 38.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 38.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 38.8
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 38.8
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 38.8
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 38.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 38.6
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 38.6
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 38.6
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 38.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 38.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 38.4
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 38.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 38.3
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 38.1
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 38.0
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 38.0
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 37.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 37.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 37.6
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 37.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 37.0
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 36.9
GTEX-P44G-0011-R2A-SM-2XCD2 30-39 years, male 36.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 36.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 36.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 36.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 36.5
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 36.5
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 36.2
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 36.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 35.8
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 35.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 35.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 35.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 35.3
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 35.1
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 35.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 34.9
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 34.8
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 34.7
GTEX-NL4W-0011-R2a-SM-2I5GV 50-59 years, male 34.6
GTEX-OXRO-0011-R2A-SM-3NB1W 60-69 years, female 34.5
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 34.5
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 34.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 34.0
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 33.7
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 33.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 33.1
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 32.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 32.9
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 32.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 32.2
GTEX-N7MS-0011-R2a-SM-2HML6 60-69 years, male 31.8
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 31.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 31.6
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 31.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 31.2
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 30.8
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 30.5
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 29.7
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 29.4
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 28.8
GTEX-PWO3-0011-R2A-SM-2S1OX 60-69 years, female 27.9
GTEX-NPJ8-0011-R2a-SM-2TC6M 40-49 years, male 26.6
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 25.8
Show allShow less

MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

94.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 94.8
FF:10158-103A5 76 years, female 94.8

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

68.9
Pig sample Sample description nTPM
Substantia nigra
nTPM: 51.6
Samples: 4

Max nTPM: 57.3
Min nTPM: 44.5
Sample A Female 56.6
Sample B Female 48.0
Sample C Male 44.5
Sample D Male 57.3
Midbrain
nTPM: 65.5
Samples: 4

Max nTPM: 85.8
Min nTPM: 49.6
Sample A Female 60.5
Sample B Female 66.1
Sample C Male 85.8
Sample D Male 49.6
Periaqueductal gray
nTPM: 47.7
Samples: 3

Max nTPM: 62.0
Min nTPM: 39.2
Sample B Female 62.0
Sample C Male 41.8
Sample D Male 39.2
Superior colliculi
nTPM: 68.9
Samples: 4

Max nTPM: 86.9
Min nTPM: 59.4
Sample A Female 66.7
Sample B Female 59.4
Sample C Male 86.9
Sample D Male 62.6

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM .

Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

266.6
Mouse sample Sample description nTPM
Midbrain
nTPM: 266.6
Samples: 4

Max nTPM: 279.6
Min nTPM: 248.3
Sample A Male 248.3
Sample B Male 265.7
Sample C Female 272.8
Sample D Female 279.6

MIDBRAIN - Allen Mouse ISHi

In situ hybridization (ISH) data generated by the Allen brain atlas from mouse brain is reported as expression energy. For more details about a particular experiment, click on the corresponding Allen experiment ID.

Max subtype Expression energyi

Max subtype Expression energy is the value for the subtype with the largest average Expression energy across the subtype samples.

19.6
Allen experiment id Experiment description Expression energy
Midbrain
Expression energy: 19.6
356858 Antisense, RP_040617_01_H08, Mouse strain C57BL/6J (56 days, male) 19.6
68192994 Antisense, RP_040617_01_H08, Mouse strain C57BL/6J (56 days, male) 18.1

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