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BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:5.7 nTPM
HPA Brain:62.2 nTPM
GTEx:5.7 nTPM
FANTOM5:33.2 Scaled Tags Per Million
Macaque:51.5 nTPM
Mouse:34.5 nTPM
Rat:22.9 nTPM
Pig:27.3 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 710
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 430
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

62.2
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 45.9
2586 Male, age 75, left hemisphere 67.3
1827 Male, age 72, unknown 55.4
2019 Male, age 18, unknown 50.8
2666 Male, age 74, left hemisphere 49.9
2828 Female, age 72, unknown 46.4
2219 Male, age 76, both hemispheres 41.3
1833 Male, age 53, unknown 39.3
1830 Male, age 51, unknown 38.4
1870 Female, age 42, unknown 36.5
2411 Female, age 72, unknown 34.0
Dorsal raphe nucleus
nTPM: 35.4
2298 Female, age 72, unknown 36.2
2750 Male, age 76, both hemispheres 36.0
2047 Male, age 72, unknown 35.7
1828 Male, age 53, unknown 34.6
2016 Female, age 72, unknown 34.3
Inferior colliculus
nTPM: 54.3
1848 Female, age 42, unknown 56.9
2849 Male, age 72, unknown 56.8
2097 Female, age 72, unknown 53.7
1890 Male, age 53, unknown 50.0
Median raphe nucleus
nTPM: 36.9
2220 Male, age 76, midline 36.9
Periaquaductal grey, anterior
nTPM: 55.6
2502 Female, age 75, unknown 57.7
1947 Male, age 18, unknown 56.5
1795 Male, age 51, unknown 52.4
Periaquaductal grey, dorsal
nTPM: 48.4
1831 Male, age 72, unknown 54.1
1840 Male, age 53, unknown 52.3
2850 Male, age 76, both hemispheres 43.9
2464 Female, age 72, unknown 43.5
Periaquaductal grey, lateral
nTPM: 45.8
2053 Male, age 18, unknown 50.9
2140 Male, age 76, both hemispheres 47.5
2272 Male, age 74, both hemispheres 38.9
Pretectal area
nTPM: 62.2
1816 Male, age 51, unknown 99.1
1944 Female, age 72, unknown 87.7
1817 Female, age 42, unknown 76.0
2007 Male, age 72, unknown 73.5
1815 Male, age 53, unknown 66.5
2667 Female, age 75, unknown 54.7
2407 Male, age 75, both hemispheres 53.6
2316 Male, age 76, right hemisphere 48.6
2825 Male, age 18, unknown 45.7
2273 Male, age 74, both hemispheres 41.6
2224 Female, age 72, unknown 37.5
Red nucleus
nTPM: 44.0
2584 Male, age 75, left hemisphere 54.6
2785 Male, age 18, unknown 53.0
2588 Male, age 74, left hemisphere 49.8
2823 Male, age 76, right hemisphere 49.3
2725 Female, age 75, unknown 47.0
2503 Female, age 72, unknown 43.0
1954 Female, age 42, unknown 40.9
1865 Male, age 51, unknown 40.2
1904 Male, age 53, unknown 39.1
1821 Female, age 72, unknown 38.0
2227 Male, age 72, unknown 37.3
2769 Male, age 72, unknown 35.2
Substantia nigra
nTPM: 43.2
1889 Female, age 72, unknown 60.7
1941 Male, age 53, unknown 54.3
2665 Male, age 74, both hemispheres 53.8
2583 Male, age 75, right hemisphere 48.8
2590 Female, age 75, unknown 48.8
2409 Female, age 72, unknown 35.1
1916 Female, age 42, unknown 34.4
1851 Male, age 51, unknown 34.0
2241 Male, age 72, unknown 33.7
2699 Male, age 18, unknown 28.3
Superior colliculus
nTPM: 57.2
2087 Female, age 72, unknown 76.3
2261 Male, age 18, unknown 69.3
2664 Male, age 75, both hemispheres 59.7
1796 Male, age 53, unknown 57.4
1995 Male, age 72, unknown 56.1
1895 Male, age 76, right hemisphere 54.8
1913 Female, age 42, unknown 52.1
1839 Male, age 51, unknown 50.5
2587 Male, age 74, left hemisphere 49.1
2668 Female, age 75, unknown 47.2
Ventral tegmental area
nTPM: 36.5
2218 Male, age 76, both hemispheres 41.0
1942 Male, age 51, unknown 40.3
2410 Female, age 72, unknown 38.2
2223 Female, age 72, unknown 34.4
1915 Female, age 42, unknown 32.7
2021 Male, age 53, unknown 32.1

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

5.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 5.7
Samples: 183

Max nTPM: 17.3
Min nTPM: 3.0
Std nTPM: 1.8
Median nTPM: 5.3
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 17.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 13.4
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 12.6
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 11.1
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 10.4
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 10.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 9.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 9.1
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 8.9
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 8.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 8.9
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 8.8
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 8.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 8.6
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 8.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 8.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 8.2
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 8.1
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 7.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 7.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 7.6
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 7.4
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 7.4
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 7.4
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 7.3
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 7.3
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 7.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 7.2
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 7.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 7.1
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 7.0
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 7.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 7.0
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 7.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 6.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 6.8
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 6.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 6.6
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 6.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 6.6
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 6.4
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 6.4
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 6.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 6.4
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 6.4
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 6.3
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 6.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 6.3
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 6.3
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 6.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 6.3
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 6.2
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 6.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 6.1
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 6.1
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 6.0
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 6.0
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 6.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 6.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 6.0
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 6.0
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 5.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 5.9
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 5.9
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 5.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 5.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 5.7
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 5.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 5.7
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 5.6
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 5.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 5.6
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 5.6
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 5.5
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 5.5
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 5.5
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 5.4
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 5.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 5.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 5.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 5.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 5.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 5.4
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 5.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 5.4
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 5.4
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 5.4
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 5.4
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 5.3
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 5.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 5.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 5.3
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 5.3
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 5.3
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 5.3
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 5.3
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 5.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 5.3
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 5.3
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 5.2
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 5.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 5.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 5.2
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 5.2
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 5.2
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 5.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 5.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 5.1
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 5.0
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 5.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 5.0
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 5.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 5.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 5.0
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 5.0
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 5.0
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 5.0
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 5.0
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 5.0
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 5.0
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 4.9
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 4.9
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 4.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 4.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 4.8
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 4.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 4.7
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 4.7
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 4.7
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 4.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 4.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 4.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 4.6
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 4.6
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 4.6
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 4.5
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 4.5
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 4.5
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 4.5
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 4.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 4.5
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 4.5
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 4.4
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 4.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 4.4
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 4.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 4.4
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 4.4
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 4.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 4.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 4.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 4.3
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 4.3
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 4.2
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 4.2
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 4.2
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 4.2
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 4.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 4.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 4.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 4.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 4.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 4.1
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 4.1
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 4.1
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 4.1
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 4.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 3.9
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 3.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 3.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 3.9
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 3.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 3.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 3.5
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 3.4
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 3.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 3.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 3.4
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 3.3
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 3.1
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 3.0
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 3.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

33.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 33.2
FF:10158-103A5 76 years, female 33.2

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

51.5
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 26.0
Samples: 1

Max nTPM: 26.0
Min nTPM: 26.0
Sample A 26.0
Midbrain
nTPM: 36.0
Samples: 1

Max nTPM: 36.0
Min nTPM: 36.0
Sample A 36.0
Superior colliculi
nTPM: 51.5
Samples: 1

Max nTPM: 51.5
Min nTPM: 51.5
Sample A 51.5

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

27.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 14.9
Samples: 3

Max nTPM: 15.4
Min nTPM: 14.5
Sample A Female 14.9
Sample B Female 14.5
Sample C Male 15.4
Midbrain
nTPM: 27.3
Samples: 3

Max nTPM: 43.0
Min nTPM: 13.6
Sample B Female 13.6
Sample C Male 43.0
Sample D Male 25.3
Periaqueductal gray
nTPM: 13.8
Samples: 3

Max nTPM: 14.3
Min nTPM: 12.8
Sample B Female 14.3
Sample C Male 14.3
Sample D Male 12.8
Superior colliculi
nTPM: 22.6
Samples: 4

Max nTPM: 28.8
Min nTPM: 18.1
Sample A Female 18.1
Sample B Female 18.4
Sample C Male 28.8
Sample D Male 25.0

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

34.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 34.5
Samples: 4

Max nTPM: 36.6
Min nTPM: 30.9
Sample A 30.9
Sample B 33.9
Sample C 36.6
Sample D 36.6

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

22.9
Rat sample Sample description nTPM
Midbrain
nTPM: 22.9
Samples: 4

Max nTPM: 25.0
Min nTPM: 22.0
Sample A 25.0
Sample A 22.0
Sample A 22.2
Sample A 22.4

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