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BETA
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  • MPC1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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Brain proteome
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:172.2 nTPM
HPA Brain:92.5 nTPM
GTEx:172.2 nTPM
FANTOM5:259.7 Scaled Tags Per Million
Macaque:61.6 nTPM
Mouse:126.9 nTPM
Pig:203.0 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 140
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 250
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

92.5
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 66.2
1870 Female, age 42, unknown 91.4
2019 Male, age 18, unknown 89.6
1830 Male, age 51, unknown 73.7
1833 Male, age 53, unknown 70.6
2411 Female, age 72, unknown 69.1
2586 Male, age 75, left hemisphere 65.7
2828 Female, age 72, unknown 57.0
1827 Male, age 72, unknown 54.7
2219 Male, age 76, both hemispheres 46.0
2666 Male, age 74, left hemisphere 43.9
Dorsal raphe nucleus
nTPM: 67.1
1828 Male, age 53, unknown 84.1
2750 Male, age 76, both hemispheres 69.2
2016 Female, age 72, unknown 68.1
2298 Female, age 72, unknown 57.5
2047 Male, age 72, unknown 56.5
Inferior colliculus
nTPM: 70.7
1890 Male, age 53, unknown 83.2
2097 Female, age 72, unknown 73.1
1848 Female, age 42, unknown 72.3
2849 Male, age 72, unknown 54.1
Median raphe nucleus
nTPM: 51.3
2220 Male, age 76, midline 51.3
Periaquaductal grey, anterior
nTPM: 53.9
1947 Male, age 18, unknown 58.7
2502 Female, age 75, unknown 58.3
1795 Male, age 51, unknown 44.8
Periaquaductal grey, dorsal
nTPM: 53.7
2850 Male, age 76, both hemispheres 61.2
2464 Female, age 72, unknown 56.4
1831 Male, age 72, unknown 50.8
1840 Male, age 53, unknown 46.4
Periaquaductal grey, lateral
nTPM: 55.5
2272 Male, age 74, both hemispheres 57.1
2140 Male, age 76, both hemispheres 56.0
2053 Male, age 18, unknown 53.5
Pretectal area
nTPM: 62.9
2007 Male, age 72, unknown 78.0
1817 Female, age 42, unknown 75.0
2273 Male, age 74, both hemispheres 68.6
2224 Female, age 72, unknown 66.5
2667 Female, age 75, unknown 63.8
1815 Male, age 53, unknown 62.3
2316 Male, age 76, right hemisphere 59.0
2407 Male, age 75, both hemispheres 58.2
1944 Female, age 72, unknown 54.4
1816 Male, age 51, unknown 53.0
2825 Male, age 18, unknown 52.7
Red nucleus
nTPM: 92.5
1821 Female, age 72, unknown 131.0
2823 Male, age 76, right hemisphere 115.9
1865 Male, age 51, unknown 110.6
1954 Female, age 42, unknown 103.3
1904 Male, age 53, unknown 98.8
2769 Male, age 72, unknown 96.1
2227 Male, age 72, unknown 94.2
2503 Female, age 72, unknown 89.4
2785 Male, age 18, unknown 81.5
2725 Female, age 75, unknown 73.1
2588 Male, age 74, left hemisphere 63.1
2584 Male, age 75, left hemisphere 52.7
Substantia nigra
nTPM: 65.8
1889 Female, age 72, unknown 83.8
2241 Male, age 72, unknown 74.8
1851 Male, age 51, unknown 72.4
2699 Male, age 18, unknown 69.3
2409 Female, age 72, unknown 66.3
1916 Female, age 42, unknown 65.3
1941 Male, age 53, unknown 62.4
2583 Male, age 75, right hemisphere 61.6
2590 Female, age 75, unknown 61.1
2665 Male, age 74, both hemispheres 41.5
Superior colliculus
nTPM: 64.1
2587 Male, age 74, left hemisphere 75.3
1913 Female, age 42, unknown 74.6
2668 Female, age 75, unknown 74.4
1995 Male, age 72, unknown 73.5
1895 Male, age 76, right hemisphere 70.2
1839 Male, age 51, unknown 59.8
2664 Male, age 75, both hemispheres 58.6
2087 Female, age 72, unknown 52.9
2261 Male, age 18, unknown 52.6
1796 Male, age 53, unknown 49.3
Ventral tegmental area
nTPM: 62.3
2410 Female, age 72, unknown 75.7
2223 Female, age 72, unknown 73.8
1915 Female, age 42, unknown 61.1
1942 Male, age 51, unknown 58.2
2218 Male, age 76, both hemispheres 53.2
2021 Male, age 53, unknown 52.0

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

172.2
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 172.2
Samples: 183

Max nTPM: 335.8
Min nTPM: 83.7
Std nTPM: 45.8
Median nTPM: 167.9
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 335.8
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 318.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 277.8
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 273.0
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 271.2
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 266.3
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 259.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 259.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 254.9
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 250.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 250.0
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 248.2
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 246.9
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 245.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 244.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 238.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 236.1
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 235.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 233.4
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 231.0
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 230.2
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 230.0
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 229.8
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 227.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 226.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 226.2
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 224.3
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 222.9
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 222.7
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 220.3
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 218.9
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 216.9
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 215.1
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 212.6
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 212.6
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 211.9
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 211.7
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 209.4
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 205.8
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 205.5
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 204.8
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 204.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 204.2
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 202.9
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 201.7
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 200.1
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 199.1
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 198.8
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 197.7
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 197.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 197.0
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 195.1
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 194.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 194.2
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 194.2
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 193.8
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 193.2
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 187.9
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 187.9
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 187.8
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 187.3
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 186.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 185.6
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 185.1
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 184.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 183.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 183.9
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 183.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 183.0
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 182.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 182.7
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 181.7
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 181.5
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 181.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 178.1
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 177.9
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 177.7
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 175.3
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 174.3
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 174.3
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 174.1
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 173.8
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 173.3
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 172.6
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 171.8
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 171.3
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 170.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 168.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 168.5
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 168.4
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 168.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 167.9
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 167.6
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 166.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 165.9
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 163.7
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 163.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 163.2
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 162.8
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 162.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 162.5
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 162.5
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 162.3
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 161.5
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 160.0
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 159.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 159.7
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 159.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 159.4
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 157.4
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 155.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 154.6
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 151.9
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 150.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 149.8
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 149.7
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 149.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 149.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 148.8
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 148.7
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 147.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 146.5
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 145.6
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 145.1
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 144.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 144.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 143.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 142.7
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 142.6
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 142.4
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 142.2
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 142.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 142.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 141.6
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 140.8
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 140.5
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 139.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 139.3
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 139.1
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 138.7
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 138.1
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 136.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 136.4
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 135.6
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 134.6
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 134.4
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 134.3
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 131.3
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 129.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 128.5
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 128.1
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 127.5
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 125.7
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 125.4
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 125.0
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 124.3
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 124.3
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 123.8
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 123.5
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 123.3
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 123.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 123.3
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 121.3
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 120.9
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 119.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 116.2
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 115.6
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 115.6
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 113.9
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 113.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 112.9
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 111.3
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 110.4
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 110.1
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 106.1
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 101.0
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 100.4
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 96.2
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 96.2
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 89.0
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 86.3
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 85.2
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 83.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

259.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 259.7
FF:10158-103A5 76 years, female 259.7

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

61.6
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 51.1
Samples: 1

Max nTPM: 51.1
Min nTPM: 51.1
Sample A 51.1
Midbrain
nTPM: 45.5
Samples: 1

Max nTPM: 45.5
Min nTPM: 45.5
Sample A 45.5
Superior colliculi
nTPM: 61.6
Samples: 1

Max nTPM: 61.6
Min nTPM: 61.6
Sample A 61.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

203.0
Pig sample Sample description nTPM
Substantia nigra
nTPM: 179.6
Samples: 3

Max nTPM: 235.3
Min nTPM: 139.4
Sample A Female 235.3
Sample B Female 164.2
Sample C Male 139.4
Midbrain
nTPM: 157.8
Samples: 3

Max nTPM: 180.4
Min nTPM: 134.7
Sample B Female 180.4
Sample C Male 158.2
Sample D Male 134.7
Periaqueductal gray
nTPM: 132.4
Samples: 3

Max nTPM: 143.5
Min nTPM: 123.3
Sample B Female 143.5
Sample C Male 123.3
Sample D Male 130.5
Superior colliculi
nTPM: 203.0
Samples: 4

Max nTPM: 243.3
Min nTPM: 178.3
Sample A Female 243.3
Sample B Female 188.6
Sample C Male 201.8
Sample D Male 178.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

126.9
Mouse sample Sample description nTPM
Midbrain
nTPM: 126.9
Samples: 4

Max nTPM: 133.6
Min nTPM: 119.9
Sample A 133.6
Sample B 125.9
Sample C 119.9
Sample D 128.2

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